CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP014151	Clostridium botulinum strain BrDura chromosome, complete genome	4 crisprs	DEDDh,csa3,DinG,WYL,cas3	0	9	6	0
CP014152	Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence	0 crisprs	cas14j,cas5,cas7b,cas8b1,cas6,c2c10_CAS-V-U3,c2c4_V-U1,cas14k,RT	0	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP014151_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP014151_1

1154293-1154580

Orphan

III-B

Consensus_repeat	Method
GATGAACATTAACATGAGATGTATTTAAATT	CRISPRCasFinder

4 spacers

The CRISPR arrays of CP014151_1

>merge|CP014151|1|1154293-1154580|CRISPRCasFinder
GATGAACATTAACATGAGATGTATTTAAATTTTGCTCACTTACTTTACTAATAATGTCATTATAGATGAACATTAACATGAGATGTATTTAAATTAATCAAGATTTAACCATTCTTTAGCTTCTCGTAGTTGAACATTAACATAGGATGTATTTAAATTTGGAAAGCTTACTAGATTTCTTACCTATATCGGGTTGAACAATAACATGAGATGCATTTAAATAAGTTAATTCTTTTGAATTTAATATCATCTGTTACACTGAACAATAACATAAGATGTATTATTAAA

>CP014151|1|1|1154293-1154580|CRISPRCasFinder
GATGAACATTAACATGAGATGTATTTAAATT	TTGCTCACTTACTTTACTAATAATGTCATTATA
GATGAACATTAACATGAGATGTATTTAAATT	AATCAAGATTTAACCATTCTTTAGCTTCTCGTA
GTTGAACATTAACATAGGATGTATTTAAATT	TGGAAAGCTTACTAGATTTCTTACCTATATCGG
GTTGAACAATAACATGAGATGCATTTAAATA	AGTTAATTCTTTTGAATTTAATATCATCTGTTAC
ACTGAACAATAACATAAGATGTATTATTAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP014151.1\|AUN17090.1\|1163835_1164138_-\|hypothetical-protein	unknown	unknown	unknown
CP014151.1\|AUN17094.1\|1168191_1168737_-\|phosphodiesterase	unknown	unknown	gnl\|CDD\|181869
CP014151.1\|AUN17088.1\|1159069_1161238_+\|phage-infection-protein	unknown	unknown	gnl\|CDD\|224428
CP014151.1\|AUN17092.1\|1165366_1167496_+\|DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|273594
CP014151.1\|AUN17076.1\|1144196_1145957_-\|dihydroxyacetone-kinase	unknown	unknown	gnl\|CDD\|237723
CP014151.1\|AUN17085.1\|1152662_1153517_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP014151.1\|AUN17079.1\|1149101_1149566_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|182099
CP014151.1\|AUN17095.1\|1169373_1169757_+\|two-component-system-response-regulator	unknown	unknown	gnl\|CDD\|381110
CP014151.1\|AUN17083.1\|1151346_1152192_+\|glyoxal-reductase	unknown	unknown	gnl\|CDD\|381383
CP014151.1\|AUN17086.1\|1155192_1156161_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223862
CP014151.1\|AUN17077.1\|1145967_1147098_-\|glycerol-dehydrogenase	unknown	unknown	gnl\|CDD\|181843
CP014151.1\|AUN17082.1\|1151025_1151229_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378906
CP014151.1\|AUN17080.1\|1149772_1150216_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
CP014151.1\|AUN17089.1\|1161263_1163423_+\|phage-infection-protein	unknown	unknown	gnl\|CDD\|224428
CP014151.1\|AUN17081.1\|1150368_1150962_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377771
CP014151.1\|AUN17078.1\|1147618_1148656_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|378400
CP014151.1\|AUN17084.1\|1152293_1152617_+\|competence-protein-TfoX	unknown	unknown	gnl\|CDD\|225612
CP014151.1\|AUN17093.1\|1167667_1168099_+\|ferritin	unknown	unknown	gnl\|CDD\|153105
CP014151.1\|AUN17087.1\|1157165_1158173_-\|adenosine-deaminase	unknown	unknown	gnl\|CDD\|236480
CP014151.1\|AUN17091.1\|1164343_1165099_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379379

Protein	Function_ID	Function_description	E-value
CP014151.1\|AUN17094.1\|1168191_1168737_-\|phosphodiesterase	gnl\|CDD\|181869	PRK09453, PRK09453, phosphodiesterase; Provisional.	1.38921e-108
CP014151.1\|AUN17088.1\|1159069_1161238_+\|phage-infection-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	1.6776e-122
CP014151.1\|AUN17092.1\|1165366_1167496_+\|DNA-helicase-RecQ	gnl\|CDD\|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
CP014151.1\|AUN17076.1\|1144196_1145957_-\|dihydroxyacetone-kinase	gnl\|CDD\|237723	PRK14479, PRK14479, dihydroxyacetone kinase; Provisional.	0
CP014151.1\|AUN17085.1\|1152662_1153517_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.80647e-09
CP014151.1\|AUN17079.1\|1149101_1149566_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|182099	PRK09831, PRK09831, GNAT family N-acetyltransferase.	2.45922e-21
CP014151.1\|AUN17095.1\|1169373_1169757_+\|two-component-system-response-regulator	gnl\|CDD\|381110	cd17562, REC_CheY4-like, phosphoacceptor receiver (REC) domain of chemotaxis response regulator CheY4 and similar CheY family proteins. CheY family chemotaxis response regulators (RRs) comprise about 17% of bacterial RRs and almost half of all RRs in archaea. This subfamily contains Vibrio cholerae CheY4 and similar CheY family RRs. CheY proteins control bacterial motility and participate in signaling phosphorelays and in protein-protein interactions. CheY RRs contain only the REC domain with no output/effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.52388e-22
CP014151.1\|AUN17083.1\|1151346_1152192_+\|glyoxal-reductase	gnl\|CDD\|381383	cd19157, AKR_AKR5G1-3, AKR5G family of aldo-keto reductase (AKR). Bacillus subtilis glyoxal reductase (GR), uncharacterized oxidoreductase YtbE, and Bacillus aryabhattai aldo-keto reductase are founding members of aldo-keto reductase family 5 member G1-3 (AKR5G1-3), respectively. GR (YvgN, EC 1.1.1.283), also called methylglyoxal reductase, reduces glyoxal and methylglyoxal (2-oxopropanal). It is not involved in vitamin B6 biosynthesis.	1.696e-168
CP014151.1\|AUN17086.1\|1155192_1156161_+\|hypothetical-protein	gnl\|CDD\|223862	COG0791, Spr, Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane].	3.45285e-36
CP014151.1\|AUN17077.1\|1145967_1147098_-\|glycerol-dehydrogenase	gnl\|CDD\|181843	PRK09423, gldA, glycerol dehydrogenase; Provisional.	0
CP014151.1\|AUN17082.1\|1151025_1151229_+\|hypothetical-protein	gnl\|CDD\|378906	pfam12663, DUF3788, Protein of unknown function (DUF3788). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 137 and 149 amino acids in length. This family may be distantly related to RelE proteins.	5.43041e-10
CP014151.1\|AUN17080.1\|1149772_1150216_+\|N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.60499e-09
CP014151.1\|AUN17089.1\|1161263_1163423_+\|phage-infection-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	7.81335e-115
CP014151.1\|AUN17081.1\|1150368_1150962_+\|hypothetical-protein	gnl\|CDD\|377771	pfam07081, DUF1349, Protein of unknown function (DUF1349). This family consists of several hypothetical bacterial proteins but contains one sequence from Saccharomyces cerevisiae. Members of this family are typically around 200 residues in length. The function of this family is unknown.	6.9018e-80
CP014151.1\|AUN17078.1\|1147618_1148656_-\|transcriptional-regulator	gnl\|CDD\|378400	pfam10114, PocR, Sensory domain found in PocR. PocR, a ligand binding domain, has a novel variant of the PAS-like Fold. Evidence suggests that it binds small hydrocarbon derivatives such as 1,3-propanediol. In (Natural history of sensor domains in bacterial signaling systems by Aravind L, LM Iyer, Anantharaman V, from 'Sensory Mechanisms in Bacteria: Molecular Aspects of Signal Recognition.' Caister Academic Press. 2010) - see (http://de.scribd.com/doc/28576661/Bacterial-Signaling-Chapter).	2.75842e-57
CP014151.1\|AUN17084.1\|1152293_1152617_+\|competence-protein-TfoX	gnl\|CDD\|225612	COG3070, TfoX, Regulator of competence-specific genes [Transcription].	1.90727e-17
CP014151.1\|AUN17093.1\|1167667_1168099_+\|ferritin	gnl\|CDD\|153105	cd01046, Rubrerythrin_like, rubrerythrin-like, diiron-binding domain. Rubrerythrin-like domain, similar to rubrerythrin, a nonheme iron binding domain found in many air-sensitive bacteria and archaea, and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system. The rubrerythrin protein has two domains, a binuclear metal center located within a four-helix bundle of the rubrerythrin domain, and a rubredoxin domain. The Rubrerythrin-like domains in this CD are singular domains (no C-terminus rubredoxin domain) and are phylogenetically distinct from rubrerythrin domains of rubrerythrin-rubredoxin proteins.	2.70117e-55
CP014151.1\|AUN17087.1\|1157165_1158173_-\|adenosine-deaminase	gnl\|CDD\|236480	PRK09358, PRK09358, adenosine deaminase; Provisional.	3.56959e-149
CP014151.1\|AUN17091.1\|1164343_1165099_+\|hypothetical-protein	gnl\|CDD\|379379	pfam13803, DUF4184, Domain of unknown function (DUF4184). This domain of unknown function contains several highly conserved histidines.	2.26267e-81

>CP014151.1|AUN17085.1|1152662_1153517_+|GNAT-family-N-acetyltransferase
MFIYDTLENIGIETLHETFLNAFSDYQVKMDLPLFKFQHMLQRRGYVPKVSIGAFNDDILVGFVLNGVRNWDGKLTAYDTGTGIIEAYRKQGITSNMLLNVRRLFQQMGVEQYLLEVIQSNTSALQLYKKQGFKILRDFECFHLDKNKYNPITTYKVEHVDMINSNDWRELTEFWDFAPSWQNSIDSINAVSDSFIYSIVRFDDNIVGYGVIDKKTGDIPQIAVNKNYRCKGIARSILTDLIKNTESYNINVINVDGRSKSMKDFLLKLGFECGVSQYEMILKL
>CP014151.1|AUN17084.1|1152293_1152617_+|competence-protein-TfoX
MASNIEFVEYVCDQISGAGDITYKKMFGDYGVYCNEKIIGLICDNQFFLKITKAGKDLLHEAIEAPAYKGAKPSFLIESLDNREYLAKIVSATYKELPMPKPKKTKK
>CP014151.1|AUN17083.1|1151346_1152192_+|glyoxal-reductase
MQDIKSYTILNNGVKMPWLGFGTYKVENGDTVIQSVKEALKIGYGHIDTASYYGNEEGVGTAIKESRIPREDIFLVSKVWNSEQGYDKTLKSFEDSIKKLGTDYLDLYLIHWPQPLSKETWKALEKLYKEGRVKAIGVSNFLVDHLKWLLEDAEIMPMVNQVEFHPQLIQKDLIEFCSKNNIQLEAWSPLMRGKVFEIQLLQDIARKYGKTISQIVLRWDLQMGVVTIPKSINPSRIKENADIFDFEISKEDMDKIQQLDKGLRVGSDPNKVYPCQSISNK
>CP014151.1|AUN17082.1|1151025_1151229_+|hypothetical-protein
MYGKKEIEQFESRRDEFSDYMKGIFNETKHYHDGKWLLIRIQNDKYINELIEMIKIKKKSKKNILHK
>CP014151.1|AUN17081.1|1150368_1150962_+|hypothetical-protein
MFRFNTKEAKWFFEPKNYLIKEDKVEIITEPNTDFWQRTYYGFRNDNAHVLYVTTDEKYFSFTVRTDFNSTALFDQCGLAIYQNSENWAKACIEFHDNNTSWLGSVVTNHGYSDWATMDIGSSVKSMWYRLSRRGSDYCFENSFDGVNFKQMRIFHLFEGAKEINFGLLACSPSKNSFKATFTEMKITDCLWEEHKA
>CP014151.1|AUN17080.1|1149772_1150216_+|N-acetyltransferase
MEIKIIKDNKRSFLDLLLLADEQESMIDKYLNRGEMFALYDGDLKSICVVTNEEEGIYEIKNLATYEKYQGQGYGSRLIKFIFEYYKDNCKTMLVGTGDSPLTIPFYKHCGFKVSHRIKNFFTDNYDHPIYESGIQLIDMVYLKKHF
>CP014151.1|AUN17079.1|1149101_1149566_+|GNAT-family-N-acetyltransferase
MNIRMYQSEDCREIVELFYNTVHSINSRDYNNAQLDVWASKEIDIDSWDKSFSQHYSIVAEESDIIIGFGDLDATGYLDTLYVHKDYQGIGVATTIANELENYAQENHISIVTTNASITAKSFFKRQGYEVVKEQFIERNGQFLKNFIMKKILG
>CP014151.1|AUN17078.1|1147618_1148656_-|transcriptional-regulator
MIKENLNLDKVIDFKKWIKLQESLALVTKAAIIIVDYKGNPVTEHSRCNRFCKAVRSNPNLVKYCQKCDSRGGLEAVRLNKPYIYLCHYNIVDIAIPIIIDGKYIGAIMAGQIKLSDNKDSDFLEQIVITPKNSMARHALEEFKEYYDEIPVLSLKEVQEIANMLFSLCNYLVEEALNKNLISEIYQKTVTPKSEIDLNILTGYTMKNIENAKKEMSNVLLDSYVKENLSSDSLDVSVSNTLKPAIEYIYNHKSENITAKKLAEVCHISPSYFSRLFSKETGKSFSSFISNLKIDWAKSLLEETDMHINEISDELGFNETGYFIKIFKKYEGVTPFVYRKYCKKN
>CP014151.1|AUN17077.1|1145967_1147098_-|glycerol-dehydrogenase
MRKAFICPTKYVQGEDEILNLGYFVKSFGESALLIAHKDDIERVKDKLDSTAKKFGITFVESAFCGECSREEVARLQEIAKNNKCACTIGLGGGKAIDTAKCVAKGNSLIIVPTIAATDAPTSHSAVLYTPDGAFDDYAYFWQSPTVILIDTTVIANAPTRFLVSGMGDALSTYFEARATSNSFSNVNAGLPCGVREGLCAPAKGTNTALTLAKACYKTLLEDGVKAKIASDCNLVTQALENIIETNILLSGLGFESAGLAAAHAIHDGLTILEGTHKYFHGEKVAFGTIAQLVLENAPKEEIDEVINFCLEIGLPVCLEDIGVDSITDEELMEVAKKSCIEEESIHSMPFKVTPEAVAAAIITADTLGKKYKSNK
>CP014151.1|AUN17076.1|1144196_1145957_-|dihydroxyacetone-kinase
MKKIINRPETVVMEMCNGIAMAHPELEFVRKYKVMKKKNINKNKVSLISGGGSGHEPAHAGFIGKGMLDAAVCGDIFASPSQIQVYKAIKATASEKGTLLIIKNYSGDIMNFKNAAHLASEDGIKVDYVKVDDDIAVEDSLYTVGRRGVAGTVLVHKIAGAAAELGFSLEKVKSIAEKAVSNVRSLGFAFSSCTVPAKRTPTFQLAEDEMEFGVGIHGEPGIVREKVATADELAKKIVDSILKDMKIDGSNNEEVALLINGFGATPLQELYLFNNSVTAELAKKNIKINRTFVGNYMTSIDMEGASVSIMKLDDELKELLSKESDTPAFKVSGPVESIEYISLEDNNDIENEVSFDLETCDCHSEIKDKKITLDNMIYIIDKMSEVIIANEVHFCELDSHAGDGDFGMSVAKGFKQLKREWKHLLKEDNMNIGKFLNECSLVIMEHCGGASGPIWGSAFRAAGKQVGDKKELSVSDFAEMMQAAVKGIQSTGERSFGRGAVVGDKTLIDALVPCADLWSESANNNTSIHEAFQKGAAAAVKGAKMTEEIVARMGRAGTVGERSIGYPDAGAYGLGVIFTEISNSLK
>CP014151.1|AUN17086.1|1155192_1156161_+|hypothetical-protein
MKKKTTILSIFLAVFMALAMNVGQVKAAATGQDIVNYAKQFQGVPYVWGGTSPSGFDCSGFVQYVYRNAAGIELPRDTYGQITKGTPVSQSNLQPGDLVFPHTGHVGIYVGNGQIIHSPQTGDVVKISPIWKFYAARRIINKPQSYINIDGGGTLACNGTSGMNLIIRDYSSDVVRAFGWVDSDPSCSWAFDVTPPNSNYTKLYKGTNKVINLRNNGSPFTPGGNYKLTVKGYDKNGKVVCERSINLKVPNGIANSSAKPIFPGSYTVTAQTVAREYPRSNGAVTGNLKKGQEVGVFAEYGNWYLVARGTPQWVEKQYLTNK
>CP014151.1|AUN17087.1|1157165_1158173_-|adenosine-deaminase
MNFKKLPKIELHCHLDGSLRVDTILDIAKKDNIPLPSYNKKELINYVSIMDDCNSLDEYLNKFFIPNKVMQTKENLKRIAFELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLEGIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGSKFIGKGVVAIDLCAGEESHFPGKYIEVLKLAKECGYRITIHAGEAGVGENVLEAITLLNAERIGHGIYIKNCAEAYKLVKEKNIPLEVCPTSNLHTKAFQSYETHPFMDFLKVGIKVTINTDNMTVSNTTITKELEMLNKFCGLSIEDYKILYLNAVEASFASPETKEILKSYANEITA
>CP014151.1|AUN17088.1|1159069_1161238_+|phage-infection-protein
MNRFKNIIKVYKRDIKSLNKNFIAIIIILGVCVLPSLYAWVNIKACWDPYENTSTVPIAVINNDKGTDFGGKELNVGNEMVKKLKSNDKIGWKFTNKKEADMGVIDGTYYASIEIPKDFSADIVSVLSDNPKHPEIIYKVDTKENPVAAKITGMAKNTLINEITTTFITTVNKTVFSSINEIGRNLEKNKNEIIKLKESIISMNRNMDLILAGLESVNTNSKNLNEYLSVVRTTFPEITKGLENINSKSSNTNETINQTNNIFNNSLNNINVILKQAISTNNRVQSVLDNLIVLNNESSNNEANSSIANLIMDIDSANKNIDSMIEFLEKINNTKPNTEVSKFIVSLNNVKGALNEEKQKLIKIQEIASNSSKVNENSINELKRNISNTNKQIESVMNVFNSNTRQELSTIINNFKNSIQDASKLIKAGNGLNTQIENLLATSTKGADLSAKLSKELIDKLTEYKGIIGQLSKKLELVSNDDLIQIISVLQNNPMLMSQTAAYPFNIKEEAVYTIPNYGSAMTPVYSVLALWVGTLILVSLLKTEVVDFEGSENITIRQKYFGKMLTFITLAAMQGFIVAVGNKAILGVYTVSFPLMLAFSVVSSIVFAIITYTLVAIFGKFGNAIAIVFMILQLAGSGGTYPIQVDPLIFRILQPFFPFTYSIGGFREAIGGPLVSSVILDFIMLILMGGIFVLIGFFLKSPLHHKISKFDEDFKASGISE
>CP014151.1|AUN17089.1|1161263_1163423_+|phage-infection-protein
MKKVFRIFSRDLKNIVKHPAAIIVVLGLCFIPSLYAWINIEACWDPYANTGNLPIAIVNKDEGMMVRGKYTNVGNGIIESLKGNKKMGWVFVDEWQANYGLNEGKYYALIEIPSNFTSGLASLKTTDPQKPNIIYRVNEKSNAIATKITNAAKGSLAKEIQTNFVYTVNKEAFKLLNNTGGQLEKNKSKILGIKSTLELGNKSIGEVKNIIDDASKDSESLKQYFNDTKDKLPLITDQINNLQKATEASKNLVNETERDLNGIAKNINNDMIYRESTNSKINSILTNLKEYNNVSNNSEMIKLVDEASKLCDSINSNIDGTIKSLEIVNILKPNKIIEELINSLKNLQEKVNGEKNKLTELKNKISTSNNNKQNINQVVESILLLNDEINKNMRNTSNIFYNQTTMIIENTAKGLNNRLDTANDILDTTKLVIPQLKALGDFGVGTSDAALKDGKKINNKLAEFKKTINKLEEKTSSLTEDNLDKIINLTQKNPEQMASFISSPINIKEEEIYNTGIFGVGLTPFYTVLAIWVGVLLMSSLISVEAEEFEGEKKLTHLQVYFGKLLLFLSIAIIQGVIVTLGDVFILGIKPASMGLLMVFTIVTAITFTFIIYTLVSIFGNLGKAIAVVIMVFQIAGAGGIYPIQTNPKIFGVLQPLWPFTYAIAGFREAIAGPVRAAVIKNLGALFIFSIGSLLLVVLKKPLHKVTEYMNDKFIETGL
>CP014151.1|AUN17090.1|1163835_1164138_-|hypothetical-protein
MEKKPSVKSSANLLAIVSLIMSIIVILPILNWFFKITPWQKLEGLPLFFGLLISPFGFLLGILSIKIQSNKLGKIGVIINTLLFLLPFIYMTLGVLIFGP
>CP014151.1|AUN17091.1|1164343_1165099_+|hypothetical-protein
MPFTFSHPAIVLPLEKKWNKYFSFTALILGSMSPDFEYFIRFKPMAIIGHGLIGFFLYNLPLCFILAYLFHKIIKKPLIAHMPKPIDSWYYNTALKPWRINSLTQVLVFSYSAIIGMITHILWDSFTHKGGKFVILFEGLRKNIEILNYDIPVYKTLQHGSTLLGVIFIILYIYSKRNKHINWKRINRIPAINNKEKVSYFTTIFCTGLIVLFVYIFLLNVSFSIKNVGSFVITFINGLFIGTIITSIKCR
>CP014151.1|AUN17092.1|1165366_1167496_+|DNA-helicase-RecQ
MLESAKDLLKKHFGYNEFRKAQEKVIESIIKKEDTVAIMPTGAGKSICYQIPALIFEGVTVVISPLISLMKDQVDSLKEVGIEATYINSSLNNLEIEERIFNAREGLYKLIYIAPERLESDSFVRSLNNLNIALVAVDEAHCVSQWGHDFRPSYTKISNFIRKLSKRPIVTAFTATATETVRRDILNSLELQNPKVFVTGFDRENLSFSVIKGEDKEKFIFGYLESNIGKVGIIYTSTRKEAESLYNKIKKKGYKVGVYHAGLNDEERKKTQEDFSFDNIEIIVATNAFGMGIDKSNVRFVIHHNIPKNMEAYYQEAGRAGRDGEESECILLFSPNDIRLQKYFIDESFLSLERKNNEYNKLRAMVDYCYTSKCLRSYILEYFGEDALEEKCNNCSTCNDNREEKDITLEAQKIFSCVYRMNERFGVNMVADVLRGSKNKKLLSLDLDGVSTYGIMEEFTQKDIVALMNKLIADDYMVTTDDKFPVVRLRPKSYDVLKGKETVSIKVSKIEKKVKADNELFEILKQLRKTISQEESVPPFMIFPDATLKELSEYMPTKEEDLLKIKGIGERKAKVYGERFIEAITEYMNEKGIDINNMDNYESTKSSKESKIKTHVLSYNLYKEGKTIKEIAEERNLKAITIQEHLFKCLSEGMEVDLDNFIKKDYEKLILDTIKKVGGTKLKPVKDELPPEVDYMCIKSVWYKYKDII
>CP014151.1|AUN17093.1|1167667_1168099_+|ferritin
MDELDIINENQLGIAANNEKIKTDLEGQFRAETGEVGLYIAMARVAQRQGFPEIAEVLKVIATEEAEHAARYAELNGKVSDCTKENLQKMLQGEIGSNKMKKSLAVKAKEENIDEVHDFIDEASRDEARHAKMLKGLLDRYFG
>CP014151.1|AUN17094.1|1168191_1168737_-|phosphodiesterase
MKLFFMSDIHGSAYYLEKALHIFEEEKADYLIILGDELYHGARNPLPKGYDPKKVTEILNSYKDKIIAVRGNCESEVDQMVLNYPIMSDYSIVLYNGKRLFLTHGHIFNKDNMPNISDGDALIYGHTHIPLAEKTNNIFVINPGSITFPKENTPHCYGILSDNLFKIKTLEGNTFKEISLI
>CP014151.1|AUN17095.1|1169373_1169757_+|two-component-system-response-regulator
MSSSQKNILVIDDSASIRSFVRNILEKANYKVYEACDGEEGIEVYKKCGNIDLVMTDIYMPKKSGLEVVVELQNKYKGTQIIVFSDGGKENFTNDSGVCEALGAAYFIRKDLIKDKLLDLVNIIFSK

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Crispr_ID: CP014151_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP014151_2

2321629-2321921

Orphan

III-B

Consensus_repeat	Method
ATTTAAATACATCTTATGTTACTGTTCAAC	CRISPRCasFinder
ATTTAAATACATCCTATGTTAAGGTTCAAC	CRT
CATTTAAATACATCCTATGTTAAGGTTCAAC	PILER-CR

4 spacers

The CRISPR arrays of CP014151_2

>merge|CP014151|2|2321629-2321921|CRISPRCasFinder,CRT,PILER-CR
GCTTAAATACATCCTATGTTAAGGTTCAACACTTTTAAATTATAATAAGAATCAAAAGTTATACTGTCATTTAAATACATCCTATGTTAAGGTTCAACGCCTATATAGGTACTTAAATCTTTTAATATAATCATTTAAATACATCCTATGTTAAGGTTCAACACATCCAACAAATGATAAGGTAATTTCATATCCACATTTAAATACATCCTATGTTAAGGTTCAACCTGCTAAACTCTTACAAAACACATGACGTAAATTAATTTAAATACATCCTATGTTAAGGTTCAACC

>CP014151|2|2|2321629-2321921|CRISPRCasFinder
GCTTAAATACATCCTATGTTAAGGTTCAAC	ACTTTTAAATTATAATAAGAATCAAAAGTTATACTGTC
ATTTAAATACATCCTATGTTAAGGTTCAAC	GCCTATATAGGTACTTAAATCTTTTAATATAATC
ATTTAAATACATCCTATGTTAAGGTTCAAC	ACATCCAACAAATGATAAGGTAATTTCATATCCAC
ATTTAAATACATCCTATGTTAAGGTTCAAC	CTGCTAAACTCTTACAAAACACATGACGTAAATTA
ATTTAAATACATCCTATGTTAAGGTTCAACC

>CP014151|2|1|2321629-2321920|CRT
GCTTAAATACATCCTATGTTAAGGTTCAAC	ACTTTTAAATTATAATAAGAATCAAAAGTTATACTGTC
ATTTAAATACATCCTATGTTAAGGTTCAAC	GCCTATATAGGTACTTAAATCTTTTAATATAATC
ATTTAAATACATCCTATGTTAAGGTTCAAC	ACATCCAACAAATGATAAGGTAATTTCATATCCAC
ATTTAAATACATCCTATGTTAAGGTTCAAC	CTGCTAAACTCTTACAAAACACATGACGTAAATTA
ATTTAAATACATCCTATGTTAAGGTTCAAC

>CP014151|2|1|2321696-2321855|PILER-CR
CATTTAAATACATCCTATGTTAAGGTTCAAC	GCCTATATAGGTACTTAAATCTTTTAATATAAT
CATTTAAATACATCCTATGTTAAGGTTCAAC	ACATCCAACAAATGATAAGGTAATTTCATATCCA
CATTTAAATACATCCTATGTTAAGGTTCAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP014151.1\|AUN18089.1\|2327480_2328221_-\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
CP014151.1\|AUN18080.1\|2317272_2318637_-\|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|236502
CP014151.1\|AUN18079.1\|2314967_2317061_-\|sugar-transporter	unknown	unknown	gnl\|CDD\|226234
CP014151.1\|AUN18087.1\|2325371_2325641_+\|peptidase-M24	unknown	unknown	gnl\|CDD\|238518
CP014151.1\|AUN18086.1\|2324433_2325048_-\|galactoside-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
CP014151.1\|AUN18088.1\|2325971_2327378_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340904
CP014151.1\|AUN18093.1\|2332144_2332942_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133378
CP014151.1\|AUN18084.1\|2320410_2321145_-\|transpeptidase-transglycosylase	unknown	unknown	gnl\|CDD\|236545
CP014151.1\|AUN18091.1\|2329418_2329940_+\|DUF4825-domain-containing-protein	unknown	unknown	gnl\|CDD\|379767
CP014151.1\|AUN18077.1\|2312734_2313502_-\|multidrug-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
CP014151.1\|AUN18092.1\|2330050_2332048_-\|2-enoate-reductase	unknown	unknown	gnl\|CDD\|239241
CP014151.1\|AUN18082.1\|2318962_2319400_-\|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|238129
CP014151.1\|AUN18083.1\|2319423_2320140_-\|transaldolase	unknown	unknown	gnl\|CDD\|183481
CP014151.1\|AUN18094.1\|2333758_2334679_-\|phenazine-biosynthesis-protein-PhzF	unknown	unknown	gnl\|CDD\|223461
CP014151.1\|AUN18075.1\|2309049_2310189_-\|3-dehydroquinate-synthase	unknown	unknown	gnl\|CDD\|341476
CP014151.1\|AUN18081.1\|2318649_2318934_-\|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|99905
CP014151.1\|AUN18076.1\|2310753_2312754_-\|ABC-transporter	unknown	unknown	gnl\|CDD\|376899
CP014151.1\|AUN18085.1\|2323320_2323494_+\|hypothetical-protein	unknown	unknown	unknown
CP014151.1\|AUN18078.1\|2314288_2314642_-\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|379915
CP014151.1\|AUN18090.1\|2328227_2329118_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117

Protein	Function_ID	Function_description	E-value
CP014151.1\|AUN18089.1\|2327480_2328221_-\|SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.0402e-11
CP014151.1\|AUN18080.1\|2317272_2318637_-\|PTS-ascorbate-transporter-subunit-IIC	gnl\|CDD\|236502	PRK09410, ulaA, PTS system ascorbate-specific transporter subunit IIC; Reviewed.	0
CP014151.1\|AUN18079.1\|2314967_2317061_-\|sugar-transporter	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.88775e-59
CP014151.1\|AUN18087.1\|2325371_2325641_+\|peptidase-M24	gnl\|CDD\|238518	cd01085, APP, X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	3.88283e-09
CP014151.1\|AUN18086.1\|2324433_2325048_-\|galactoside-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	1.28102e-96
CP014151.1\|AUN18088.1\|2325971_2327378_+\|MFS-transporter	gnl\|CDD\|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.39716e-119
CP014151.1\|AUN18093.1\|2332144_2332942_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	5.44368e-15
CP014151.1\|AUN18084.1\|2320410_2321145_-\|transpeptidase-transglycosylase	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	3.70682e-11
CP014151.1\|AUN18091.1\|2329418_2329940_+\|DUF4825-domain-containing-protein	gnl\|CDD\|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	2.45556e-24
CP014151.1\|AUN18077.1\|2312734_2313502_-\|multidrug-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.08756e-103
CP014151.1\|AUN18092.1\|2330050_2332048_-\|2-enoate-reductase	gnl\|CDD\|239241	cd02931, ER_like_FMN, Enoate reductase (ER)-like FMN-binding domain. Enoate reductase catalyzes the NADH-dependent reduction of carbon-carbon double bonds of several molecules, including nonactivated 2-enoates, alpha,beta-unsaturated aldehydes, cyclic ketones, and methylketones. ERs are similar to 2,4-dienoyl-CoA reductase from E. coli and to the old yellow enzyme from Saccharomyces cerevisiae.	0
CP014151.1\|AUN18082.1\|2318962_2319400_-\|PTS-maltose-transporter-subunit-IIBC	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	4.79769e-38
CP014151.1\|AUN18083.1\|2319423_2320140_-\|transaldolase	gnl\|CDD\|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	6.47741e-157
CP014151.1\|AUN18094.1\|2333758_2334679_-\|phenazine-biosynthesis-protein-PhzF	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	1.47974e-90
CP014151.1\|AUN18075.1\|2309049_2310189_-\|3-dehydroquinate-synthase	gnl\|CDD\|341476	cd08197, DOIS, 2-deoxy-scyllo-inosose synthase (DOIS) catalyzes carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose. 2-deoxy-scyllo-inosose synthase (DOIS) catalyzes carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose through a multistep reaction in the biosynthesis of aminoglycoside antibiotics. 2-deoxystreptamine (DOS)-containing aminoglycoside antibiotics includes neomycin, kanamycin, gentamicin, and ribostamycin. They are important antibacterial agents. DOIS is a homolog of the dehydroquinate synthase which catalyzes the cyclization of 3-deoxy-D-arabino-heputulosonate-7-phosphate to dehydroquinate (DHQ) in the shikimate pathway.	4.38741e-154
CP014151.1\|AUN18081.1\|2318649_2318934_-\|PTS-maltose-transporter-subunit-IIBC	gnl\|CDD\|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	2.52704e-28
CP014151.1\|AUN18076.1\|2310753_2312754_-\|ABC-transporter	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	0.000772087
CP014151.1\|AUN18078.1\|2314288_2314642_-\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|379915	pfam17032, zinc_ribbon_15, zinc-ribbon family. This zinc-ribbon region is found on a set of largely microsporidia-specific proteins.	0.000151797
CP014151.1\|AUN18090.1\|2328227_2329118_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.5893e-25

>CP014151.1|AUN18084.1|2320410_2321145_-|transpeptidase-transglycosylase
MDKFRNMKKSHVALLVVIYMVLMGSFPRFTGWITIFSAIAVGGYFLKNKKDLKELTTKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKLMAEKAKQEQEIKQEEQKKIEEKKLVEEQKRIQEEESKKKAAEEKRKQEDEAKKKAVEEQKKQEELKRKQEEENKIKAENEQAQAAFAQSTGKGNSNDQSNESENVDTNQNYTVYKTRTGSKYHSSGCRYLRKSCYETTVSQARNEGLTPCSVCTP
>CP014151.1|AUN18083.1|2319423_2320140_-|transaldolase
MKYNDLKIKIFADGADLNGMLDAYNKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVEALKSGVDSIVSVFAGRIADTGEDPVTIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>CP014151.1|AUN18082.1|2318962_2319400_-|PTS-maltose-transporter-subunit-IIBC
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPVNFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>CP014151.1|AUN18081.1|2318649_2318934_-|PTS-maltose-transporter-subunit-IIBC
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEELKK
>CP014151.1|AUN18080.1|2317272_2318637_-|PTS-ascorbate-transporter-subunit-IIC
MLGLLQFLRDVLKQPALLMGIMALVGLVALKKPGHKVLTGTLKPILGYLMLGAGADFIVANLEPLGGMIQTGFNITGVVPNNEAIVAVAQKVLGVETMSILVVGLLINLVIARFTKYKYVFLTGHHSFFMACLLSAVLGTSGMKGTELILFGGFLLGAWSAISPAIGQKYTLKVTDGDEIAMGHFGSLAYYVSAWVGSKVGKPEESTENIEIPEKWGFLRDTTISTAITMMVFYIVAAVAAGPEYVSKLSDGMSPILFAIMSSLKFAVGVTIVYNGVRMILGDLIPAFQGIATKIIPDAIPAVDCAVFFPYAPTAVIIGFVSSFIGGIIGMVLLGVAGGVLIIPGLVPHFFCGSTAGIFGNATGGKKGAVIGSFVNGLLITFAPALLLPVLSTLGFKNTTFGDFDFGVLGIIIGKTSNLAGKTGIIIIAMLMLLALIVPNFIKTKSKALNNIEE
>CP014151.1|AUN18079.1|2314967_2317061_-|sugar-transporter
MLNKRCSNILQMIVNNEKPITIKEISKKVNKSPRTVRYDLDKIDDYLTEIEFPKLERKSNLGISLDLKDEEIKKLFKIIGKINNYDYVLSQKERVFYIIYELLNKSEFVTINMLSDRMMVSRSTIINDLIEVKKWLLENKITLESSKGQGIKILGRERDLRRAAVKLFFQSMDSINFFNVTTLKLFNDIDIDFIRNTIKIAEEQMETSFSDDAFNNLVIHIAIAIKRIELSKDIIMDSEELKNLRKTAEYAIASGIAKMLEDRFKISIPEDEIGYITIHILGSNTSTLENIVKDDWIYLHLIVFKLIENVENITGINFSKDNKLFDSLAQHIRPAIYRLKHDIKVKNPLIEEIKEKYSYIFESIEEGVKFIEEDIGDSVNQEEIGYLTLHFMASIERSKNKKHRKPNVLIVCATGIGTSKFISNKLKSIFDINIIDTISSHTMEKVLKYNKNIDLIVTTIPLKVKGIKCIEVNTFLTEKNISELGLYFAKFIRDNSEECNSSCKYEERDKVQEILNIIKENCTIHDYYKLRNKLALYLNIKDPTLTEDPKPSLKELLKPDFIKLNEEAEDWEDAVRKSGEILMNNGCVKESYIDAMVNTVKNMGPYIVIAPGIAMPHAAPEDGVLKTGISMLTLKDPISFGNSEHDPVSVIISICSIDRVNHMKALKELMSIMDQEDFLSKVKSMKTPSEIDPILYS
>CP014151.1|AUN18078.1|2314288_2314642_-|zinc-ribbon-domain-containing-protein
MIIWGWGKVTKKIIGAVFERTCNYCNTDEVWNLCVVRTWFTLFFIPIIPYKKQYCIACPKCWSYIELTQEEFEKIKIDITSSSNNINEKAVTDNIKYAGKTETQINYLKQMEEYANK
>CP014151.1|AUN18077.1|2312734_2313502_-|multidrug-ABC-transporter-ATP-binding-protein
MQNILSVEKIEKYYGNKDNVTKAIDNISFKVDEGEFVGIMGPSGSGKTTLLNCISTIDNVTTGKIMINNNDITRLKSKSLDKFRQNELGFIFQDFNLLDTLTAYENIALALTIQGEKTSKIDGKVKSVAKYLEIEKVLEKYPYQMSGGQKQRVASARAIVTNPSLILADEPTGALDSKSARLLLERFEKLNKELKTTILMVTHDAFAASYAHRILFIKDGKIFNELVRGKDTRKEFFNKIIEVTSLLGGDDNNVF
>CP014151.1|AUN18076.1|2310753_2312754_-|ABC-transporter
MIIMYSKIALKNIKKSYKDYTIYFLTLILAVCIFYSFNSIDSQKALTDIKSSGGSYVSKLMDFMSAVSVFVSIILGSLILYANNFLIKKRKKELGIYMILGMGKRKISKILVRETSIVGVISLIAGLIIGIGVSQGLSVLTLKLFEVSINEYRFAVSTRAIGKTILYFGIMFLLVMIFNAFVISKYKIIDLLTSGRKNENIKFKNTFIYLLSFLLCVVLLGFAYRSILKIGLDLREPMFKLSIAFVIIGTVLFFFSLAGVILYVVNKNKKIYFKGLNMFVIKQINSKVNTNFLSMSLICLMLFITILVLSTGISFKNGLEEGLKRQAPFDASITISNNSKKDNLEDVLDKINFKRSKNEKYATCNEYFSGIKLGSLLSITDKYYKDAEVSFVKISDYNKMLKLRGKKEINLNKNEILIMSSDNNLVKQINKKIKSSKKFNIKGKEYLVKNNEIIDENLATDAFGNNVFTIIISDEFLYDYNKIANSTLNVMYSDKNREENNKKYNEIYKNYLDGKYKSLNISYIGAFSKDDIYSGRRGGTTTVLFVAIYLGLVFLITSMAVLALQQLSEASDSIERYKALKKIGANSKMIDKTIFLQTLIYFTLPMILALIHSVIGIKVINDGISPFTKIDISFSALITALIFSVVYAGYFYTTYIGYKNIVESNI
>CP014151.1|AUN18075.1|2309049_2310189_-|3-dehydroquinate-synthase
MYMNLAQKINDDYYHPEVKLETNLLESSPIYLGCNIWRESLLGKMMDLNTDKFFLITDDVVYNLFGKELLEYMNRKVSVKLIKLPSGEKHKNIKVFNDLMEDLFDNNVTKSSILISLGGGVVGNITGLAAALAFRGIRFFHIPTTFMSQTDSILSRKQGINSFYGKNMIGSYYTPLFNFIDTSFLTFDSERFIRGSFVETVKNGFIYDADFLNKLKSVIKNDFNINQEGIFNLVKMSIESKLPIMKADPTEKGLAMILEYGHTIGHAIEKLSYGKLSHGESVSIGMMVAARVSEKLGYLSKQDVKEHLDILSALKTPTKIPSNIKISDIINRIKLDNKKDMNGIRFVVLESIGKCINTDGSYMIKVPFNIINEAIEETC
>CP014151.1|AUN18085.1|2323320_2323494_+|hypothetical-protein
MVLDMLELTIKSFVVIYIVKLILKHNLFISKLVIKIKFLGIHIELNGKEKKHPSDQE
>CP014151.1|AUN18086.1|2324433_2325048_-|galactoside-O-acetyltransferase
MNQKDRMLAGLPYKAWLDGLPEERMANKKKIYEYNHCFPDEHEKIHKLIRDILGKAGADVHIEAPFYCDYGKNIQVGDNFFANYNCIILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGIHIGNNVVIGSGSVVIKDIPDNVIAIGNPCKVIREITEEDRKYYYKNYEFDVDDYKE
>CP014151.1|AUN18087.1|2325371_2325641_+|peptidase-M24
MHLFINENKLNDEIKSNLKENGALFIHPYNKIYKEVITEISSSNKLDAFPAEQGRFIRPSFEPISSFGEHATIVTCILLMENSFIVVTV
>CP014151.1|AUN18088.1|2325971_2327378_+|MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVVADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSTESVSIKSTEKAKARPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGGFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>CP014151.1|AUN18089.1|2327480_2328221_-|SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPHAPGDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFESSIEKFSPEEKYDYIFITSGSFSLFLDEDSAFNVLVKIKEALAPKGKFVFAAETTANIIPDREEYLENCHVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGGNLLGKEEMDFRIKLYDFGELDKLILKAGFKRRHVFSDFNRRESIDKNTETFLYECYI
>CP014151.1|AUN18090.1|2328227_2329118_-|AraC-family-transcriptional-regulator
MNYRKDIENCIEYIEEHIRESLTVNQITKEIGYSIYHFCRVFSFLKGMPLMEYVGRRKLSLSTIDLLEGQKIIDVALKWGFETPSSFARAFRKEFGCSPTQYIKKMKAYYKSKGILTVGNFMIDPYIIKKEAFKVAGYGIKTNVADSKYTKDVASFWSNYTGENLESKLYKILSPLKHGEVGLCIPCSDSGDITYLLGVVVEDFSKVTSDMITVEVSKAQYAVFTTNPVNTVDSKDQREFAKIIKQSWKYIFDEWFKNNDYEYDEEKLDFEFYDERCHLRPDTVMDIYVPIKKLER
>CP014151.1|AUN18091.1|2329418_2329940_+|DUF4825-domain-containing-protein
MKNKFKILVPLVLILSLNLIGCGVNSERKSKENVKNSSKVETYDLIKYKGAYVGDNSSVGSIIKNLPANEYSAGFSLQTTKEPYEIIVNYKTNENLGEENYNKFWKDKKVEELLEKNAVVLLYLIPNAEIIKFNVENIGEESYKYDRKNLEQKYENLKNLFKDNDSLNKFLNN
>CP014151.1|AUN18092.1|2330050_2332048_-|2-enoate-reductase
MKDKYKVLYDPIKIGKLEIKNRYVLAPMGPGGMCNADGSFNERGIEFYVERAKGGTGLIMTGVTMVENNIEKCALPSMPCPTINPLNFITTGNELTERVHAYGAKIFLQLSAGFGRVSIPSIVGKVAVAPSKIPHRFLPGVTCRELTTEEVKEYVKAFGESAEIAKKAGFDGVEIHAVHEGYLLDQFAISFFNHRTDEYGGSLENRLRFACEVVQEIKKRCGQDFPVSLRYSIKSFIKDWCKGGLPDEEFEEKGRDIPEGIEAAKILVAAGYDALNGDVGSYDSWYWSHPPMYQKKGLYLPYNEILKKVVDVPIITAGRMEDPELSSDAILSGKTDMIALGRPLLADAEIPNKIFEDKYDKVRPCLSCQEGCMGRLQNFATVSCAVNPACGREKEYGLKKAEQIKKVLVVGGGVAGMEAARVAAIRGHKVTLIEKNGYLGGNIVPGGVPDFKDDDRALVKWYEGILKDLGVEIKLNVDASKENIKGFGADEVLLATGSSPRTLNIEGADNVYSAEDVLMERKNVGEKVIIIGGGLVGCETALWLKQQGKEVTIVEMQNDILQVGGPLCHANHDMLIDLIKFNKIDVKTSSYISKKTDKGLVLNTNGQESIINADSAVVAIGYLSQKDLYNEVRFDIPNARLIGDANKVQNIMYAIWSAYEVAKNI
>CP014151.1|AUN18093.1|2332144_2332942_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEKRETMYQLEALKRAQYYMNLADAIEEHLVSIRRIEELLNKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHAKEIKSTSCIHTIVMADEDFTQQPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>CP014151.1|AUN18094.1|2333758_2334679_-|phenazine-biosynthesis-protein-PhzF
MRKFEYTLVDVFTNQVFGGNQLAVFKDAEKLSNEEMQSIARELNFSETTFVTDIGPNHKKLRIFTPKTELPMAGHPTIGTAFVLADEGAVETREGINKLIFEEGVGEIAVSIHVEGGRIKSIEMEQPMPVFGKVFGDIRTAAELLSIDIADIDTTSPIQTVSTGVPFLYIPLKSLDVISKIKLRLDTWEKFFSVSEDTKHIFAFTRETLHAGSTIHSRMFAPAMGIVEDPATGGASGPLGAYLVEHGLVAHGYDGKYMIINEQGIEMGRPSFINITVSKTYNNFSEIKIGGTCVKFGSGLIELPTL

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Crispr_ID: CP014151_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP014151_3

2322174-2322923

Orphan

III-B

Consensus_repeat	Method
ATTTAAATACATCTTATGTTACTGTTCAAC	CRISPRCasFinder
ATTTAAATACATCTTATGTTACTGTTCAAC	CRT
ATTTAAATACATCTTATGTTACTGTTCAAC	PILER-CR

11 spacers

The CRISPR arrays of CP014151_3

>merge|CP014151|3|2322174-2322923|CRISPRCasFinder,CRT,PILER-CR
GCTTAAATACATCTCATGTTATTGTTCAACCTAAAGCACTTATGGCCGCTTGTTTCATTTCTTCATTTAAATACATCTTATGTTACTATTCAACATTCCATTCAAGATAGCCACATTCTCAAGCGGTTATAAATTTAAATACATCTTATGTTACTGTTCAACGATTTGTAAGAGATTATACTCTGAATTAGTTATAATTTAAATACATCTTATGTTACTGTTCAACTAACATATGACATAATAGATTATTACACATCAAGTAATTTAAATACATCTTATGTTACTGTTCAACTGTTTTAGTAAGTGGCCAAACAGGTTGTGGAAAAACATTTAAATACATCTTATGTTACTGTTCAACAAATTGAGATGTTAGAAATACAAGATTTATTAAGCTATTTAAATACATCTTATGTTACTGTTCAACGCAGTAGGAATGAATATAGGTTTCTATCATTTTAATTTAAATACATCTTATGTTACTGTTCAACCTAATAAAGTGGCGACTGGATTTATGAAAATGTAATTTAAATACATCTTATGTTACTGTTCAACAACTTATACGACCTAAAAGAGTCATCACTTTGAGTAATTTAAATACATCTTATGTTACTGTTCAACGAATATGCAAATAGAACATTTAAGGTCAATGTAGCATTTAAATACATCTTATGTTACTGTTCAACTGGGAACATTAATGCTGCACAAATAGCAATGGGGCTATTTAAATACATCTTATGTTACTGTTCAACC

>CP014151|3|3|2322174-2322923|CRISPRCasFinder
GCTTAAATACATCTCATGTTATTGTTCAAC	CTAAAGCACTTATGGCCGCTTGTTTCATTTCTTC
ATTTAAATACATCTTATGTTACTATTCAAC	ATTCCATTCAAGATAGCCACATTCTCAAGCGGTTATAA
ATTTAAATACATCTTATGTTACTGTTCAAC	GATTTGTAAGAGATTATACTCTGAATTAGTTATA
ATTTAAATACATCTTATGTTACTGTTCAAC	TAACATATGACATAATAGATTATTACACATCAAGTA
ATTTAAATACATCTTATGTTACTGTTCAAC	TGTTTTAGTAAGTGGCCAAACAGGTTGTGGAAAAAC
ATTTAAATACATCTTATGTTACTGTTCAAC	AAATTGAGATGTTAGAAATACAAGATTTATTAAGCT
ATTTAAATACATCTTATGTTACTGTTCAAC	GCAGTAGGAATGAATATAGGTTTCTATCATTTTA
ATTTAAATACATCTTATGTTACTGTTCAAC	CTAATAAAGTGGCGACTGGATTTATGAAAATGTA
ATTTAAATACATCTTATGTTACTGTTCAAC	AACTTATACGACCTAAAAGAGTCATCACTTTGAGTA
ATTTAAATACATCTTATGTTACTGTTCAAC	GAATATGCAAATAGAACATTTAAGGTCAATGTAGC
ATTTAAATACATCTTATGTTACTGTTCAAC	TGGGAACATTAATGCTGCACAAATAGCAATGGGGCT
ATTTAAATACATCTTATGTTACTGTTCAACC

>CP014151|3|2|2322174-2322922|CRT
GCTTAAATACATCTCATGTTATTGTTCAAC	CTAAAGCACTTATGGCCGCTTGTTTCATTTCTTC
ATTTAAATACATCTTATGTTACTATTCAAC	ATTCCATTCAAGATAGCCACATTCTCAAGCGGTTATAA
ATTTAAATACATCTTATGTTACTGTTCAAC	GATTTGTAAGAGATTATACTCTGAATTAGTTATA
ATTTAAATACATCTTATGTTACTGTTCAAC	TAACATATGACATAATAGATTATTACACATCAAGTA
ATTTAAATACATCTTATGTTACTGTTCAAC	TGTTTTAGTAAGTGGCCAAACAGGTTGTGGAAAAAC
ATTTAAATACATCTTATGTTACTGTTCAAC	AAATTGAGATGTTAGAAATACAAGATTTATTAAGCT
ATTTAAATACATCTTATGTTACTGTTCAAC	GCAGTAGGAATGAATATAGGTTTCTATCATTTTA
ATTTAAATACATCTTATGTTACTGTTCAAC	CTAATAAAGTGGCGACTGGATTTATGAAAATGTA
ATTTAAATACATCTTATGTTACTGTTCAAC	AACTTATACGACCTAAAAGAGTCATCACTTTGAGTA
ATTTAAATACATCTTATGTTACTGTTCAAC	GAATATGCAAATAGAACATTTAAGGTCAATGTAGC
ATTTAAATACATCTTATGTTACTGTTCAAC	TGGGAACATTAATGCTGCACAAATAGCAATGGGGCT
ATTTAAATACATCTTATGTTACTGTTCAAC

>CP014151|3|2|2322238-2322922|PILER-CR
ATTTAAATACATCTTATGTTACTATTCAAC	ATTCCATTCAAGATAGCCACATTCTCAAGCGGTTATAA
ATTTAAATACATCTTATGTTACTGTTCAAC	GATTTGTAAGAGATTATACTCTGAATTAGTTATA
ATTTAAATACATCTTATGTTACTGTTCAAC	TAACATATGACATAATAGATTATTACACATCAAGTA
ATTTAAATACATCTTATGTTACTGTTCAAC	TGTTTTAGTAAGTGGCCAAACAGGTTGTGGAAAAAC
ATTTAAATACATCTTATGTTACTGTTCAAC	AAATTGAGATGTTAGAAATACAAGATTTATTAAGCT
ATTTAAATACATCTTATGTTACTGTTCAAC	GCAGTAGGAATGAATATAGGTTTCTATCATTTTA
ATTTAAATACATCTTATGTTACTGTTCAAC	CTAATAAAGTGGCGACTGGATTTATGAAAATGTA
ATTTAAATACATCTTATGTTACTGTTCAAC	AACTTATACGACCTAAAAGAGTCATCACTTTGAGTA
ATTTAAATACATCTTATGTTACTGTTCAAC	GAATATGCAAATAGAACATTTAAGGTCAATGTAGC
ATTTAAATACATCTTATGTTACTGTTCAAC	TGGGAACATTAATGCTGCACAAATAGCAATGGGGCT
ATTTAAATACATCTTATGTTACTGTTCAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP014151.1\|AUN18089.1\|2327480_2328221_-\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
CP014151.1\|AUN18080.1\|2317272_2318637_-\|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|236502
CP014151.1\|AUN18079.1\|2314967_2317061_-\|sugar-transporter	unknown	unknown	gnl\|CDD\|226234
CP014151.1\|AUN18087.1\|2325371_2325641_+\|peptidase-M24	unknown	unknown	gnl\|CDD\|238518
CP014151.1\|AUN18086.1\|2324433_2325048_-\|galactoside-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
CP014151.1\|AUN18088.1\|2325971_2327378_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340904
CP014151.1\|AUN18093.1\|2332144_2332942_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133378
CP014151.1\|AUN18084.1\|2320410_2321145_-\|transpeptidase-transglycosylase	unknown	unknown	gnl\|CDD\|236545
CP014151.1\|AUN18091.1\|2329418_2329940_+\|DUF4825-domain-containing-protein	unknown	unknown	gnl\|CDD\|379767
CP014151.1\|AUN18077.1\|2312734_2313502_-\|multidrug-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
CP014151.1\|AUN18092.1\|2330050_2332048_-\|2-enoate-reductase	unknown	unknown	gnl\|CDD\|239241
CP014151.1\|AUN18082.1\|2318962_2319400_-\|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|238129
CP014151.1\|AUN18083.1\|2319423_2320140_-\|transaldolase	unknown	unknown	gnl\|CDD\|183481
CP014151.1\|AUN18094.1\|2333758_2334679_-\|phenazine-biosynthesis-protein-PhzF	unknown	unknown	gnl\|CDD\|223461
CP014151.1\|AUN18075.1\|2309049_2310189_-\|3-dehydroquinate-synthase	unknown	unknown	gnl\|CDD\|341476
CP014151.1\|AUN18081.1\|2318649_2318934_-\|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|99905
CP014151.1\|AUN18076.1\|2310753_2312754_-\|ABC-transporter	unknown	unknown	gnl\|CDD\|376899
CP014151.1\|AUN18085.1\|2323320_2323494_+\|hypothetical-protein	unknown	unknown	unknown
CP014151.1\|AUN18078.1\|2314288_2314642_-\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|379915
CP014151.1\|AUN18090.1\|2328227_2329118_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117

Protein	Function_ID	Function_description	E-value
CP014151.1\|AUN18089.1\|2327480_2328221_-\|SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.0402e-11
CP014151.1\|AUN18080.1\|2317272_2318637_-\|PTS-ascorbate-transporter-subunit-IIC	gnl\|CDD\|236502	PRK09410, ulaA, PTS system ascorbate-specific transporter subunit IIC; Reviewed.	0
CP014151.1\|AUN18079.1\|2314967_2317061_-\|sugar-transporter	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.88775e-59
CP014151.1\|AUN18087.1\|2325371_2325641_+\|peptidase-M24	gnl\|CDD\|238518	cd01085, APP, X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	3.88283e-09
CP014151.1\|AUN18086.1\|2324433_2325048_-\|galactoside-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	1.28102e-96
CP014151.1\|AUN18088.1\|2325971_2327378_+\|MFS-transporter	gnl\|CDD\|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.39716e-119
CP014151.1\|AUN18093.1\|2332144_2332942_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	5.44368e-15
CP014151.1\|AUN18084.1\|2320410_2321145_-\|transpeptidase-transglycosylase	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	3.70682e-11
CP014151.1\|AUN18091.1\|2329418_2329940_+\|DUF4825-domain-containing-protein	gnl\|CDD\|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	2.45556e-24
CP014151.1\|AUN18077.1\|2312734_2313502_-\|multidrug-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.08756e-103
CP014151.1\|AUN18092.1\|2330050_2332048_-\|2-enoate-reductase	gnl\|CDD\|239241	cd02931, ER_like_FMN, Enoate reductase (ER)-like FMN-binding domain. Enoate reductase catalyzes the NADH-dependent reduction of carbon-carbon double bonds of several molecules, including nonactivated 2-enoates, alpha,beta-unsaturated aldehydes, cyclic ketones, and methylketones. ERs are similar to 2,4-dienoyl-CoA reductase from E. coli and to the old yellow enzyme from Saccharomyces cerevisiae.	0
CP014151.1\|AUN18082.1\|2318962_2319400_-\|PTS-maltose-transporter-subunit-IIBC	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	4.79769e-38
CP014151.1\|AUN18083.1\|2319423_2320140_-\|transaldolase	gnl\|CDD\|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	6.47741e-157
CP014151.1\|AUN18094.1\|2333758_2334679_-\|phenazine-biosynthesis-protein-PhzF	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	1.47974e-90
CP014151.1\|AUN18075.1\|2309049_2310189_-\|3-dehydroquinate-synthase	gnl\|CDD\|341476	cd08197, DOIS, 2-deoxy-scyllo-inosose synthase (DOIS) catalyzes carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose. 2-deoxy-scyllo-inosose synthase (DOIS) catalyzes carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose through a multistep reaction in the biosynthesis of aminoglycoside antibiotics. 2-deoxystreptamine (DOS)-containing aminoglycoside antibiotics includes neomycin, kanamycin, gentamicin, and ribostamycin. They are important antibacterial agents. DOIS is a homolog of the dehydroquinate synthase which catalyzes the cyclization of 3-deoxy-D-arabino-heputulosonate-7-phosphate to dehydroquinate (DHQ) in the shikimate pathway.	4.38741e-154
CP014151.1\|AUN18081.1\|2318649_2318934_-\|PTS-maltose-transporter-subunit-IIBC	gnl\|CDD\|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	2.52704e-28
CP014151.1\|AUN18076.1\|2310753_2312754_-\|ABC-transporter	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	0.000772087
CP014151.1\|AUN18078.1\|2314288_2314642_-\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|379915	pfam17032, zinc_ribbon_15, zinc-ribbon family. This zinc-ribbon region is found on a set of largely microsporidia-specific proteins.	0.000151797
CP014151.1\|AUN18090.1\|2328227_2329118_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.5893e-25

>CP014151.1|AUN18084.1|2320410_2321145_-|transpeptidase-transglycosylase
MDKFRNMKKSHVALLVVIYMVLMGSFPRFTGWITIFSAIAVGGYFLKNKKDLKELTTKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKLMAEKAKQEQEIKQEEQKKIEEKKLVEEQKRIQEEESKKKAAEEKRKQEDEAKKKAVEEQKKQEELKRKQEEENKIKAENEQAQAAFAQSTGKGNSNDQSNESENVDTNQNYTVYKTRTGSKYHSSGCRYLRKSCYETTVSQARNEGLTPCSVCTP
>CP014151.1|AUN18083.1|2319423_2320140_-|transaldolase
MKYNDLKIKIFADGADLNGMLDAYNKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVEALKSGVDSIVSVFAGRIADTGEDPVTIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>CP014151.1|AUN18082.1|2318962_2319400_-|PTS-maltose-transporter-subunit-IIBC
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPVNFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>CP014151.1|AUN18081.1|2318649_2318934_-|PTS-maltose-transporter-subunit-IIBC
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEELKK
>CP014151.1|AUN18080.1|2317272_2318637_-|PTS-ascorbate-transporter-subunit-IIC
MLGLLQFLRDVLKQPALLMGIMALVGLVALKKPGHKVLTGTLKPILGYLMLGAGADFIVANLEPLGGMIQTGFNITGVVPNNEAIVAVAQKVLGVETMSILVVGLLINLVIARFTKYKYVFLTGHHSFFMACLLSAVLGTSGMKGTELILFGGFLLGAWSAISPAIGQKYTLKVTDGDEIAMGHFGSLAYYVSAWVGSKVGKPEESTENIEIPEKWGFLRDTTISTAITMMVFYIVAAVAAGPEYVSKLSDGMSPILFAIMSSLKFAVGVTIVYNGVRMILGDLIPAFQGIATKIIPDAIPAVDCAVFFPYAPTAVIIGFVSSFIGGIIGMVLLGVAGGVLIIPGLVPHFFCGSTAGIFGNATGGKKGAVIGSFVNGLLITFAPALLLPVLSTLGFKNTTFGDFDFGVLGIIIGKTSNLAGKTGIIIIAMLMLLALIVPNFIKTKSKALNNIEE
>CP014151.1|AUN18079.1|2314967_2317061_-|sugar-transporter
MLNKRCSNILQMIVNNEKPITIKEISKKVNKSPRTVRYDLDKIDDYLTEIEFPKLERKSNLGISLDLKDEEIKKLFKIIGKINNYDYVLSQKERVFYIIYELLNKSEFVTINMLSDRMMVSRSTIINDLIEVKKWLLENKITLESSKGQGIKILGRERDLRRAAVKLFFQSMDSINFFNVTTLKLFNDIDIDFIRNTIKIAEEQMETSFSDDAFNNLVIHIAIAIKRIELSKDIIMDSEELKNLRKTAEYAIASGIAKMLEDRFKISIPEDEIGYITIHILGSNTSTLENIVKDDWIYLHLIVFKLIENVENITGINFSKDNKLFDSLAQHIRPAIYRLKHDIKVKNPLIEEIKEKYSYIFESIEEGVKFIEEDIGDSVNQEEIGYLTLHFMASIERSKNKKHRKPNVLIVCATGIGTSKFISNKLKSIFDINIIDTISSHTMEKVLKYNKNIDLIVTTIPLKVKGIKCIEVNTFLTEKNISELGLYFAKFIRDNSEECNSSCKYEERDKVQEILNIIKENCTIHDYYKLRNKLALYLNIKDPTLTEDPKPSLKELLKPDFIKLNEEAEDWEDAVRKSGEILMNNGCVKESYIDAMVNTVKNMGPYIVIAPGIAMPHAAPEDGVLKTGISMLTLKDPISFGNSEHDPVSVIISICSIDRVNHMKALKELMSIMDQEDFLSKVKSMKTPSEIDPILYS
>CP014151.1|AUN18078.1|2314288_2314642_-|zinc-ribbon-domain-containing-protein
MIIWGWGKVTKKIIGAVFERTCNYCNTDEVWNLCVVRTWFTLFFIPIIPYKKQYCIACPKCWSYIELTQEEFEKIKIDITSSSNNINEKAVTDNIKYAGKTETQINYLKQMEEYANK
>CP014151.1|AUN18077.1|2312734_2313502_-|multidrug-ABC-transporter-ATP-binding-protein
MQNILSVEKIEKYYGNKDNVTKAIDNISFKVDEGEFVGIMGPSGSGKTTLLNCISTIDNVTTGKIMINNNDITRLKSKSLDKFRQNELGFIFQDFNLLDTLTAYENIALALTIQGEKTSKIDGKVKSVAKYLEIEKVLEKYPYQMSGGQKQRVASARAIVTNPSLILADEPTGALDSKSARLLLERFEKLNKELKTTILMVTHDAFAASYAHRILFIKDGKIFNELVRGKDTRKEFFNKIIEVTSLLGGDDNNVF
>CP014151.1|AUN18076.1|2310753_2312754_-|ABC-transporter
MIIMYSKIALKNIKKSYKDYTIYFLTLILAVCIFYSFNSIDSQKALTDIKSSGGSYVSKLMDFMSAVSVFVSIILGSLILYANNFLIKKRKKELGIYMILGMGKRKISKILVRETSIVGVISLIAGLIIGIGVSQGLSVLTLKLFEVSINEYRFAVSTRAIGKTILYFGIMFLLVMIFNAFVISKYKIIDLLTSGRKNENIKFKNTFIYLLSFLLCVVLLGFAYRSILKIGLDLREPMFKLSIAFVIIGTVLFFFSLAGVILYVVNKNKKIYFKGLNMFVIKQINSKVNTNFLSMSLICLMLFITILVLSTGISFKNGLEEGLKRQAPFDASITISNNSKKDNLEDVLDKINFKRSKNEKYATCNEYFSGIKLGSLLSITDKYYKDAEVSFVKISDYNKMLKLRGKKEINLNKNEILIMSSDNNLVKQINKKIKSSKKFNIKGKEYLVKNNEIIDENLATDAFGNNVFTIIISDEFLYDYNKIANSTLNVMYSDKNREENNKKYNEIYKNYLDGKYKSLNISYIGAFSKDDIYSGRRGGTTTVLFVAIYLGLVFLITSMAVLALQQLSEASDSIERYKALKKIGANSKMIDKTIFLQTLIYFTLPMILALIHSVIGIKVINDGISPFTKIDISFSALITALIFSVVYAGYFYTTYIGYKNIVESNI
>CP014151.1|AUN18075.1|2309049_2310189_-|3-dehydroquinate-synthase
MYMNLAQKINDDYYHPEVKLETNLLESSPIYLGCNIWRESLLGKMMDLNTDKFFLITDDVVYNLFGKELLEYMNRKVSVKLIKLPSGEKHKNIKVFNDLMEDLFDNNVTKSSILISLGGGVVGNITGLAAALAFRGIRFFHIPTTFMSQTDSILSRKQGINSFYGKNMIGSYYTPLFNFIDTSFLTFDSERFIRGSFVETVKNGFIYDADFLNKLKSVIKNDFNINQEGIFNLVKMSIESKLPIMKADPTEKGLAMILEYGHTIGHAIEKLSYGKLSHGESVSIGMMVAARVSEKLGYLSKQDVKEHLDILSALKTPTKIPSNIKISDIINRIKLDNKKDMNGIRFVVLESIGKCINTDGSYMIKVPFNIINEAIEETC
>CP014151.1|AUN18085.1|2323320_2323494_+|hypothetical-protein
MVLDMLELTIKSFVVIYIVKLILKHNLFISKLVIKIKFLGIHIELNGKEKKHPSDQE
>CP014151.1|AUN18086.1|2324433_2325048_-|galactoside-O-acetyltransferase
MNQKDRMLAGLPYKAWLDGLPEERMANKKKIYEYNHCFPDEHEKIHKLIRDILGKAGADVHIEAPFYCDYGKNIQVGDNFFANYNCIILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGIHIGNNVVIGSGSVVIKDIPDNVIAIGNPCKVIREITEEDRKYYYKNYEFDVDDYKE
>CP014151.1|AUN18087.1|2325371_2325641_+|peptidase-M24
MHLFINENKLNDEIKSNLKENGALFIHPYNKIYKEVITEISSSNKLDAFPAEQGRFIRPSFEPISSFGEHATIVTCILLMENSFIVVTV
>CP014151.1|AUN18088.1|2325971_2327378_+|MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVVADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSTESVSIKSTEKAKARPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGGFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>CP014151.1|AUN18089.1|2327480_2328221_-|SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPHAPGDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFESSIEKFSPEEKYDYIFITSGSFSLFLDEDSAFNVLVKIKEALAPKGKFVFAAETTANIIPDREEYLENCHVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGGNLLGKEEMDFRIKLYDFGELDKLILKAGFKRRHVFSDFNRRESIDKNTETFLYECYI
>CP014151.1|AUN18090.1|2328227_2329118_-|AraC-family-transcriptional-regulator
MNYRKDIENCIEYIEEHIRESLTVNQITKEIGYSIYHFCRVFSFLKGMPLMEYVGRRKLSLSTIDLLEGQKIIDVALKWGFETPSSFARAFRKEFGCSPTQYIKKMKAYYKSKGILTVGNFMIDPYIIKKEAFKVAGYGIKTNVADSKYTKDVASFWSNYTGENLESKLYKILSPLKHGEVGLCIPCSDSGDITYLLGVVVEDFSKVTSDMITVEVSKAQYAVFTTNPVNTVDSKDQREFAKIIKQSWKYIFDEWFKNNDYEYDEEKLDFEFYDERCHLRPDTVMDIYVPIKKLER
>CP014151.1|AUN18091.1|2329418_2329940_+|DUF4825-domain-containing-protein
MKNKFKILVPLVLILSLNLIGCGVNSERKSKENVKNSSKVETYDLIKYKGAYVGDNSSVGSIIKNLPANEYSAGFSLQTTKEPYEIIVNYKTNENLGEENYNKFWKDKKVEELLEKNAVVLLYLIPNAEIIKFNVENIGEESYKYDRKNLEQKYENLKNLFKDNDSLNKFLNN
>CP014151.1|AUN18092.1|2330050_2332048_-|2-enoate-reductase
MKDKYKVLYDPIKIGKLEIKNRYVLAPMGPGGMCNADGSFNERGIEFYVERAKGGTGLIMTGVTMVENNIEKCALPSMPCPTINPLNFITTGNELTERVHAYGAKIFLQLSAGFGRVSIPSIVGKVAVAPSKIPHRFLPGVTCRELTTEEVKEYVKAFGESAEIAKKAGFDGVEIHAVHEGYLLDQFAISFFNHRTDEYGGSLENRLRFACEVVQEIKKRCGQDFPVSLRYSIKSFIKDWCKGGLPDEEFEEKGRDIPEGIEAAKILVAAGYDALNGDVGSYDSWYWSHPPMYQKKGLYLPYNEILKKVVDVPIITAGRMEDPELSSDAILSGKTDMIALGRPLLADAEIPNKIFEDKYDKVRPCLSCQEGCMGRLQNFATVSCAVNPACGREKEYGLKKAEQIKKVLVVGGGVAGMEAARVAAIRGHKVTLIEKNGYLGGNIVPGGVPDFKDDDRALVKWYEGILKDLGVEIKLNVDASKENIKGFGADEVLLATGSSPRTLNIEGADNVYSAEDVLMERKNVGEKVIIIGGGLVGCETALWLKQQGKEVTIVEMQNDILQVGGPLCHANHDMLIDLIKFNKIDVKTSSYISKKTDKGLVLNTNGQESIINADSAVVAIGYLSQKDLYNEVRFDIPNARLIGDANKVQNIMYAIWSAYEVAKNI
>CP014151.1|AUN18093.1|2332144_2332942_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEKRETMYQLEALKRAQYYMNLADAIEEHLVSIRRIEELLNKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHAKEIKSTSCIHTIVMADEDFTQQPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>CP014151.1|AUN18094.1|2333758_2334679_-|phenazine-biosynthesis-protein-PhzF
MRKFEYTLVDVFTNQVFGGNQLAVFKDAEKLSNEEMQSIARELNFSETTFVTDIGPNHKKLRIFTPKTELPMAGHPTIGTAFVLADEGAVETREGINKLIFEEGVGEIAVSIHVEGGRIKSIEMEQPMPVFGKVFGDIRTAAELLSIDIADIDTTSPIQTVSTGVPFLYIPLKSLDVISKIKLRLDTWEKFFSVSEDTKHIFAFTRETLHAGSTIHSRMFAPAMGIVEDPATGGASGPLGAYLVEHGLVAHGYDGKYMIINEQGIEMGRPSFINITVSKTYNNFSEIKIGGTCVKFGSGLIELPTL

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Crispr_ID: CP014151_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP014151_4

2323834-2323930

Orphan

III-B

Consensus_repeat	Method
ATTTAAATACATCTTATGTTACTGTTCAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP014151_4

>merge|CP014151|4|2323834-2323930|CRISPRCasFinder
TTTTCAGTACATCTCATGTTAATGTTCAATGAAATAAAGGACAGGCTAGGAATATCTACAAACGCAGATTTAAATACATCTCATGTTAATGTTCAAT

>CP014151|4|4|2323834-2323930|CRISPRCasFinder
TTTTCAGTACATCTCATGTTAATGTTCAAT	GAAATAAAGGACAGGCTAGGAATATCTACAAACGCAG
ATTTAAATACATCTCATGTTAATGTTCAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP014151.1\|AUN18089.1\|2327480_2328221_-\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
CP014151.1\|AUN18080.1\|2317272_2318637_-\|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|236502
CP014151.1\|AUN18079.1\|2314967_2317061_-\|sugar-transporter	unknown	unknown	gnl\|CDD\|226234
CP014151.1\|AUN18095.1\|2335002_2336496_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224089
CP014151.1\|AUN18087.1\|2325371_2325641_+\|peptidase-M24	unknown	unknown	gnl\|CDD\|238518
CP014151.1\|AUN18086.1\|2324433_2325048_-\|galactoside-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
CP014151.1\|AUN18088.1\|2325971_2327378_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340904
CP014151.1\|AUN18093.1\|2332144_2332942_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133378
CP014151.1\|AUN18084.1\|2320410_2321145_-\|transpeptidase-transglycosylase	unknown	unknown	gnl\|CDD\|236545
CP014151.1\|AUN18091.1\|2329418_2329940_+\|DUF4825-domain-containing-protein	unknown	unknown	gnl\|CDD\|379767
CP014151.1\|AUN18077.1\|2312734_2313502_-\|multidrug-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
CP014151.1\|AUN18092.1\|2330050_2332048_-\|2-enoate-reductase	unknown	unknown	gnl\|CDD\|239241
CP014151.1\|AUN18082.1\|2318962_2319400_-\|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|238129
CP014151.1\|AUN18083.1\|2319423_2320140_-\|transaldolase	unknown	unknown	gnl\|CDD\|183481
CP014151.1\|AUN18094.1\|2333758_2334679_-\|phenazine-biosynthesis-protein-PhzF	unknown	unknown	gnl\|CDD\|223461
CP014151.1\|AUN18081.1\|2318649_2318934_-\|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|99905
CP014151.1\|AUN18076.1\|2310753_2312754_-\|ABC-transporter	unknown	unknown	gnl\|CDD\|376899
CP014151.1\|AUN18085.1\|2323320_2323494_+\|hypothetical-protein	unknown	unknown	unknown
CP014151.1\|AUN18078.1\|2314288_2314642_-\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|379915
CP014151.1\|AUN18090.1\|2328227_2329118_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117

Protein	Function_ID	Function_description	E-value
CP014151.1\|AUN18089.1\|2327480_2328221_-\|SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.0402e-11
CP014151.1\|AUN18080.1\|2317272_2318637_-\|PTS-ascorbate-transporter-subunit-IIC	gnl\|CDD\|236502	PRK09410, ulaA, PTS system ascorbate-specific transporter subunit IIC; Reviewed.	0
CP014151.1\|AUN18079.1\|2314967_2317061_-\|sugar-transporter	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.88775e-59
CP014151.1\|AUN18095.1\|2335002_2336496_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	4.11607e-120
CP014151.1\|AUN18087.1\|2325371_2325641_+\|peptidase-M24	gnl\|CDD\|238518	cd01085, APP, X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	3.88283e-09
CP014151.1\|AUN18088.1\|2325971_2327378_+\|MFS-transporter	gnl\|CDD\|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.39716e-119
CP014151.1\|AUN18093.1\|2332144_2332942_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	5.44368e-15
CP014151.1\|AUN18086.1\|2324433_2325048_-\|galactoside-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	1.28102e-96
CP014151.1\|AUN18091.1\|2329418_2329940_+\|DUF4825-domain-containing-protein	gnl\|CDD\|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	2.45556e-24
CP014151.1\|AUN18077.1\|2312734_2313502_-\|multidrug-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.08756e-103
CP014151.1\|AUN18092.1\|2330050_2332048_-\|2-enoate-reductase	gnl\|CDD\|239241	cd02931, ER_like_FMN, Enoate reductase (ER)-like FMN-binding domain. Enoate reductase catalyzes the NADH-dependent reduction of carbon-carbon double bonds of several molecules, including nonactivated 2-enoates, alpha,beta-unsaturated aldehydes, cyclic ketones, and methylketones. ERs are similar to 2,4-dienoyl-CoA reductase from E. coli and to the old yellow enzyme from Saccharomyces cerevisiae.	0
CP014151.1\|AUN18082.1\|2318962_2319400_-\|PTS-maltose-transporter-subunit-IIBC	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	4.79769e-38
CP014151.1\|AUN18083.1\|2319423_2320140_-\|transaldolase	gnl\|CDD\|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	6.47741e-157
CP014151.1\|AUN18094.1\|2333758_2334679_-\|phenazine-biosynthesis-protein-PhzF	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	1.47974e-90
CP014151.1\|AUN18081.1\|2318649_2318934_-\|PTS-maltose-transporter-subunit-IIBC	gnl\|CDD\|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	2.52704e-28
CP014151.1\|AUN18076.1\|2310753_2312754_-\|ABC-transporter	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	0.000772087
CP014151.1\|AUN18084.1\|2320410_2321145_-\|transpeptidase-transglycosylase	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	3.70682e-11
CP014151.1\|AUN18078.1\|2314288_2314642_-\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|379915	pfam17032, zinc_ribbon_15, zinc-ribbon family. This zinc-ribbon region is found on a set of largely microsporidia-specific proteins.	0.000151797
CP014151.1\|AUN18090.1\|2328227_2329118_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.5893e-25

>CP014151.1|AUN18085.1|2323320_2323494_+|hypothetical-protein
MVLDMLELTIKSFVVIYIVKLILKHNLFISKLVIKIKFLGIHIELNGKEKKHPSDQE
>CP014151.1|AUN18084.1|2320410_2321145_-|transpeptidase-transglycosylase
MDKFRNMKKSHVALLVVIYMVLMGSFPRFTGWITIFSAIAVGGYFLKNKKDLKELTTKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKLMAEKAKQEQEIKQEEQKKIEEKKLVEEQKRIQEEESKKKAAEEKRKQEDEAKKKAVEEQKKQEELKRKQEEENKIKAENEQAQAAFAQSTGKGNSNDQSNESENVDTNQNYTVYKTRTGSKYHSSGCRYLRKSCYETTVSQARNEGLTPCSVCTP
>CP014151.1|AUN18083.1|2319423_2320140_-|transaldolase
MKYNDLKIKIFADGADLNGMLDAYNKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVEALKSGVDSIVSVFAGRIADTGEDPVTIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>CP014151.1|AUN18082.1|2318962_2319400_-|PTS-maltose-transporter-subunit-IIBC
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPVNFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>CP014151.1|AUN18081.1|2318649_2318934_-|PTS-maltose-transporter-subunit-IIBC
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEELKK
>CP014151.1|AUN18080.1|2317272_2318637_-|PTS-ascorbate-transporter-subunit-IIC
MLGLLQFLRDVLKQPALLMGIMALVGLVALKKPGHKVLTGTLKPILGYLMLGAGADFIVANLEPLGGMIQTGFNITGVVPNNEAIVAVAQKVLGVETMSILVVGLLINLVIARFTKYKYVFLTGHHSFFMACLLSAVLGTSGMKGTELILFGGFLLGAWSAISPAIGQKYTLKVTDGDEIAMGHFGSLAYYVSAWVGSKVGKPEESTENIEIPEKWGFLRDTTISTAITMMVFYIVAAVAAGPEYVSKLSDGMSPILFAIMSSLKFAVGVTIVYNGVRMILGDLIPAFQGIATKIIPDAIPAVDCAVFFPYAPTAVIIGFVSSFIGGIIGMVLLGVAGGVLIIPGLVPHFFCGSTAGIFGNATGGKKGAVIGSFVNGLLITFAPALLLPVLSTLGFKNTTFGDFDFGVLGIIIGKTSNLAGKTGIIIIAMLMLLALIVPNFIKTKSKALNNIEE
>CP014151.1|AUN18079.1|2314967_2317061_-|sugar-transporter
MLNKRCSNILQMIVNNEKPITIKEISKKVNKSPRTVRYDLDKIDDYLTEIEFPKLERKSNLGISLDLKDEEIKKLFKIIGKINNYDYVLSQKERVFYIIYELLNKSEFVTINMLSDRMMVSRSTIINDLIEVKKWLLENKITLESSKGQGIKILGRERDLRRAAVKLFFQSMDSINFFNVTTLKLFNDIDIDFIRNTIKIAEEQMETSFSDDAFNNLVIHIAIAIKRIELSKDIIMDSEELKNLRKTAEYAIASGIAKMLEDRFKISIPEDEIGYITIHILGSNTSTLENIVKDDWIYLHLIVFKLIENVENITGINFSKDNKLFDSLAQHIRPAIYRLKHDIKVKNPLIEEIKEKYSYIFESIEEGVKFIEEDIGDSVNQEEIGYLTLHFMASIERSKNKKHRKPNVLIVCATGIGTSKFISNKLKSIFDINIIDTISSHTMEKVLKYNKNIDLIVTTIPLKVKGIKCIEVNTFLTEKNISELGLYFAKFIRDNSEECNSSCKYEERDKVQEILNIIKENCTIHDYYKLRNKLALYLNIKDPTLTEDPKPSLKELLKPDFIKLNEEAEDWEDAVRKSGEILMNNGCVKESYIDAMVNTVKNMGPYIVIAPGIAMPHAAPEDGVLKTGISMLTLKDPISFGNSEHDPVSVIISICSIDRVNHMKALKELMSIMDQEDFLSKVKSMKTPSEIDPILYS
>CP014151.1|AUN18078.1|2314288_2314642_-|zinc-ribbon-domain-containing-protein
MIIWGWGKVTKKIIGAVFERTCNYCNTDEVWNLCVVRTWFTLFFIPIIPYKKQYCIACPKCWSYIELTQEEFEKIKIDITSSSNNINEKAVTDNIKYAGKTETQINYLKQMEEYANK
>CP014151.1|AUN18077.1|2312734_2313502_-|multidrug-ABC-transporter-ATP-binding-protein
MQNILSVEKIEKYYGNKDNVTKAIDNISFKVDEGEFVGIMGPSGSGKTTLLNCISTIDNVTTGKIMINNNDITRLKSKSLDKFRQNELGFIFQDFNLLDTLTAYENIALALTIQGEKTSKIDGKVKSVAKYLEIEKVLEKYPYQMSGGQKQRVASARAIVTNPSLILADEPTGALDSKSARLLLERFEKLNKELKTTILMVTHDAFAASYAHRILFIKDGKIFNELVRGKDTRKEFFNKIIEVTSLLGGDDNNVF
>CP014151.1|AUN18076.1|2310753_2312754_-|ABC-transporter
MIIMYSKIALKNIKKSYKDYTIYFLTLILAVCIFYSFNSIDSQKALTDIKSSGGSYVSKLMDFMSAVSVFVSIILGSLILYANNFLIKKRKKELGIYMILGMGKRKISKILVRETSIVGVISLIAGLIIGIGVSQGLSVLTLKLFEVSINEYRFAVSTRAIGKTILYFGIMFLLVMIFNAFVISKYKIIDLLTSGRKNENIKFKNTFIYLLSFLLCVVLLGFAYRSILKIGLDLREPMFKLSIAFVIIGTVLFFFSLAGVILYVVNKNKKIYFKGLNMFVIKQINSKVNTNFLSMSLICLMLFITILVLSTGISFKNGLEEGLKRQAPFDASITISNNSKKDNLEDVLDKINFKRSKNEKYATCNEYFSGIKLGSLLSITDKYYKDAEVSFVKISDYNKMLKLRGKKEINLNKNEILIMSSDNNLVKQINKKIKSSKKFNIKGKEYLVKNNEIIDENLATDAFGNNVFTIIISDEFLYDYNKIANSTLNVMYSDKNREENNKKYNEIYKNYLDGKYKSLNISYIGAFSKDDIYSGRRGGTTTVLFVAIYLGLVFLITSMAVLALQQLSEASDSIERYKALKKIGANSKMIDKTIFLQTLIYFTLPMILALIHSVIGIKVINDGISPFTKIDISFSALITALIFSVVYAGYFYTTYIGYKNIVESNI
>CP014151.1|AUN18086.1|2324433_2325048_-|galactoside-O-acetyltransferase
MNQKDRMLAGLPYKAWLDGLPEERMANKKKIYEYNHCFPDEHEKIHKLIRDILGKAGADVHIEAPFYCDYGKNIQVGDNFFANYNCIILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGIHIGNNVVIGSGSVVIKDIPDNVIAIGNPCKVIREITEEDRKYYYKNYEFDVDDYKE
>CP014151.1|AUN18087.1|2325371_2325641_+|peptidase-M24
MHLFINENKLNDEIKSNLKENGALFIHPYNKIYKEVITEISSSNKLDAFPAEQGRFIRPSFEPISSFGEHATIVTCILLMENSFIVVTV
>CP014151.1|AUN18088.1|2325971_2327378_+|MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVVADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSTESVSIKSTEKAKARPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGGFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>CP014151.1|AUN18089.1|2327480_2328221_-|SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPHAPGDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFESSIEKFSPEEKYDYIFITSGSFSLFLDEDSAFNVLVKIKEALAPKGKFVFAAETTANIIPDREEYLENCHVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGGNLLGKEEMDFRIKLYDFGELDKLILKAGFKRRHVFSDFNRRESIDKNTETFLYECYI
>CP014151.1|AUN18090.1|2328227_2329118_-|AraC-family-transcriptional-regulator
MNYRKDIENCIEYIEEHIRESLTVNQITKEIGYSIYHFCRVFSFLKGMPLMEYVGRRKLSLSTIDLLEGQKIIDVALKWGFETPSSFARAFRKEFGCSPTQYIKKMKAYYKSKGILTVGNFMIDPYIIKKEAFKVAGYGIKTNVADSKYTKDVASFWSNYTGENLESKLYKILSPLKHGEVGLCIPCSDSGDITYLLGVVVEDFSKVTSDMITVEVSKAQYAVFTTNPVNTVDSKDQREFAKIIKQSWKYIFDEWFKNNDYEYDEEKLDFEFYDERCHLRPDTVMDIYVPIKKLER
>CP014151.1|AUN18091.1|2329418_2329940_+|DUF4825-domain-containing-protein
MKNKFKILVPLVLILSLNLIGCGVNSERKSKENVKNSSKVETYDLIKYKGAYVGDNSSVGSIIKNLPANEYSAGFSLQTTKEPYEIIVNYKTNENLGEENYNKFWKDKKVEELLEKNAVVLLYLIPNAEIIKFNVENIGEESYKYDRKNLEQKYENLKNLFKDNDSLNKFLNN
>CP014151.1|AUN18092.1|2330050_2332048_-|2-enoate-reductase
MKDKYKVLYDPIKIGKLEIKNRYVLAPMGPGGMCNADGSFNERGIEFYVERAKGGTGLIMTGVTMVENNIEKCALPSMPCPTINPLNFITTGNELTERVHAYGAKIFLQLSAGFGRVSIPSIVGKVAVAPSKIPHRFLPGVTCRELTTEEVKEYVKAFGESAEIAKKAGFDGVEIHAVHEGYLLDQFAISFFNHRTDEYGGSLENRLRFACEVVQEIKKRCGQDFPVSLRYSIKSFIKDWCKGGLPDEEFEEKGRDIPEGIEAAKILVAAGYDALNGDVGSYDSWYWSHPPMYQKKGLYLPYNEILKKVVDVPIITAGRMEDPELSSDAILSGKTDMIALGRPLLADAEIPNKIFEDKYDKVRPCLSCQEGCMGRLQNFATVSCAVNPACGREKEYGLKKAEQIKKVLVVGGGVAGMEAARVAAIRGHKVTLIEKNGYLGGNIVPGGVPDFKDDDRALVKWYEGILKDLGVEIKLNVDASKENIKGFGADEVLLATGSSPRTLNIEGADNVYSAEDVLMERKNVGEKVIIIGGGLVGCETALWLKQQGKEVTIVEMQNDILQVGGPLCHANHDMLIDLIKFNKIDVKTSSYISKKTDKGLVLNTNGQESIINADSAVVAIGYLSQKDLYNEVRFDIPNARLIGDANKVQNIMYAIWSAYEVAKNI
>CP014151.1|AUN18093.1|2332144_2332942_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEKRETMYQLEALKRAQYYMNLADAIEEHLVSIRRIEELLNKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHAKEIKSTSCIHTIVMADEDFTQQPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>CP014151.1|AUN18094.1|2333758_2334679_-|phenazine-biosynthesis-protein-PhzF
MRKFEYTLVDVFTNQVFGGNQLAVFKDAEKLSNEEMQSIARELNFSETTFVTDIGPNHKKLRIFTPKTELPMAGHPTIGTAFVLADEGAVETREGINKLIFEEGVGEIAVSIHVEGGRIKSIEMEQPMPVFGKVFGDIRTAAELLSIDIADIDTTSPIQTVSTGVPFLYIPLKSLDVISKIKLRLDTWEKFFSVSEDTKHIFAFTRETLHAGSTIHSRMFAPAMGIVEDPATGGASGPLGAYLVEHGLVAHGYDGKYMIINEQGIEMGRPSFINITVSKTYNNFSEIKIGGTCVKFGSGLIELPTL
>CP014151.1|AUN18095.1|2335002_2336496_+|GntR-family-transcriptional-regulator
MNIKIDKNSLITITQQLAHYFSDRIMSGFIKAGQKLPSIRSLAKELGISPMTIIKAYNNLEQNGLVTTIQGKGTYVNERNSTVKSNNITEKDSFQWQMSVPDYLSRSQFRYNPNLSYSNDYYNLSVASLNHKLLPTKTILKDSLGLIQNDIKLLSQYPPAQGDYEFRNIMSQYLRLKEIATSPENILVTSGSQQGISLIASTFIGPGDIVVMETPTYPGAIDLFKCRGAVILTVPVDSEGMRTDILMNLCDKHSPKLIYTIPNFHNPTGYSMSSKRKAELLDIARYNDILIVEDDPWNEISYKREKIKSIKSMDTDGHVVYIKSLSKILGPSYRLAVIISESSILSRLIAAKANHDLGTSVLIQKTIINFIQSNKITYYIESLNKQLVKRRDKVISLLKSHAPSGMKWAIPEGGINIWITLPKNFNVEKLLSYSITTKNISFLPGTICYPNEVEFNNLRICFTYLDEEFIEDTIIELCNLIKLLYTTKNITAYRPII

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP014151_3	3.3\|2322336\|34\|CP014151\|CRISPRCasFinder,CRT,PILER-CR	2322336-2322369	34	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	26508-26541	0	1.0
CP014151_3	3.4\|2322400\|36\|CP014151\|CRISPRCasFinder,CRT,PILER-CR	2322400-2322435	36	NZ_CP014218	Clostridium botulinum strain B515 plasmid pRSJ21_3, complete sequence	50868-50903	0	1.0
CP014151_3	3.9\|2322726\|36\|CP014151\|CRISPRCasFinder,CRT,PILER-CR	2322726-2322761	36	NZ_CP013682	Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence	113908-113943	2	0.944
CP014151_3	3.9\|2322726\|36\|CP014151\|CRISPRCasFinder,CRT,PILER-CR	2322726-2322761	36	NZ_CP013295	Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence	124624-124659	2	0.944
CP014151_3	3.11\|2322857\|36\|CP014151\|CRISPRCasFinder,CRT,PILER-CR	2322857-2322892	36	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	110543-110578	2	0.944
CP014151_3	3.11\|2322857\|36\|CP014151\|CRISPRCasFinder,CRT,PILER-CR	2322857-2322892	36	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	155980-156015	2	0.944
CP014151_2	2.1\|2321659\|38\|CP014151\|CRISPRCasFinder,CRT	2321659-2321696	38	KX229736	Campylobacter phage PC5, complete genome	59595-59632	7	0.816
CP014151_2	2.5\|2321727\|33\|CP014151\|PILER-CR	2321727-2321759	33	NC_010632	Nostoc punctiforme PCC 73102 plasmid pNPUN02, complete sequence	182908-182940	8	0.758
CP014151_1	1.1\|1154324\|33\|CP014151\|CRISPRCasFinder	1154324-1154356	33	NZ_MF706324	Staphylococcus aureus strain 4185 plasmid pRJ101, complete sequence	5283-5315	9	0.727
CP014151_1	1.2\|1154388\|33\|CP014151\|CRISPRCasFinder	1154388-1154420	33	JQ768459	Pseudomonas phage Lu11, complete genome	105953-105985	9	0.727
CP014151_2	2.2\|2321727\|34\|CP014151\|CRISPRCasFinder,CRT	2321727-2321760	34	NC_010632	Nostoc punctiforme PCC 73102 plasmid pNPUN02, complete sequence	182907-182940	9	0.735
CP014151_3	3.4\|2322400\|36\|CP014151\|CRISPRCasFinder,CRT,PILER-CR	2322400-2322435	36	NZ_CP014173	Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence	1-26	10	0.722

1. spacer 3.3|2322336|34|CP014151|CRISPRCasFinder,CRT,PILER-CR matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 0, identity: 1.0

gatttgtaagagattatactctgaattagttata	CRISPR spacer
gatttgtaagagattatactctgaattagttata	Protospacer
**********************************

2. spacer 3.4|2322400|36|CP014151|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014218 (Clostridium botulinum strain B515 plasmid pRSJ21_3, complete sequence) position: , mismatch: 0, identity: 1.0

taacatatgacataatagattattacacatcaagta	CRISPR spacer
taacatatgacataatagattattacacatcaagta	Protospacer
************************************

3. spacer 3.9|2322726|36|CP014151|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013682 (Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence) position: , mismatch: 2, identity: 0.944

aacttatacgacctaaaagagtcatcactttgagta	CRISPR spacer
aacttatacgacctaaaagagttattactttgagta	Protospacer
**********************.**.**********

4. spacer 3.9|2322726|36|CP014151|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013295 (Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence) position: , mismatch: 2, identity: 0.944

aacttatacgacctaaaagagtcatcactttgagta	CRISPR spacer
aacttatacgacctaaaagagttattactttgagta	Protospacer
**********************.**.**********

5. spacer 3.11|2322857|36|CP014151|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 2, identity: 0.944

tgggaacattaatgctgcacaaatagcaatggggct	CRISPR spacer
tggaaacattaatgctgcacaaatagcaatgggact	Protospacer
***.*****************************.**

6. spacer 3.11|2322857|36|CP014151|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 2, identity: 0.944

tgggaacattaatgctgcacaaatagcaatggggct	CRISPR spacer
tggaaacattaatgctgcacaaatagcaatgggact	Protospacer
***.*****************************.**

7. spacer 2.1|2321659|38|CP014151|CRISPRCasFinder,CRT matches to KX229736 (Campylobacter phage PC5, complete genome) position: , mismatch: 7, identity: 0.816

acttttaaattataataagaatcaaaagtta-tactgtc	CRISPR spacer
tcttttatattataataagaatcaaatgttagtatcat-	Protospacer
 ****** ****************** **** **...*

8. spacer 2.5|2321727|33|CP014151|PILER-CR matches to NC_010632 (Nostoc punctiforme PCC 73102 plasmid pNPUN02, complete sequence) position: , mismatch: 8, identity: 0.758

gcctatataggtacttaaatcttttaatataat	CRISPR spacer
ttaaaaataggtacttaattcttttaaaatagt	Protospacer
 .  * ************ ******** ***.*

9. spacer 1.1|1154324|33|CP014151|CRISPRCasFinder matches to NZ_MF706324 (Staphylococcus aureus strain 4185 plasmid pRJ101, complete sequence) position: , mismatch: 9, identity: 0.727

ttgctcacttactttactaataatgtcattata	CRISPR spacer
tttgaatgttaatttactaataatatcattatt	Protospacer
**      *** ************.*******

10. spacer 1.2|1154388|33|CP014151|CRISPRCasFinder matches to JQ768459 (Pseudomonas phage Lu11, complete genome) position: , mismatch: 9, identity: 0.727

aatcaagatttaaccattctttagcttctcgta	CRISPR spacer
catcaagattcaacgattctttagccatgtgca	Protospacer
 *********.*** **********. . .*.*

11. spacer 2.2|2321727|34|CP014151|CRISPRCasFinder,CRT matches to NC_010632 (Nostoc punctiforme PCC 73102 plasmid pNPUN02, complete sequence) position: , mismatch: 9, identity: 0.735

gcctatataggtacttaaatcttttaatataatc	CRISPR spacer
ttaaaaataggtacttaattcttttaaaatagtt	Protospacer
 .  * ************ ******** ***.*.

12. spacer 3.4|2322400|36|CP014151|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014173 (Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence) position: , mismatch: 10, identity: 0.722

taacatatgacataatagattattacacatcaagta	CRISPR spacer
taacatatgacataatagattattac----------	Protospacer
**************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

22448 : 56377

Paenibacillus_phage(17.39%)

terminase,head,tail,capsid,portal,integrase,tRNA

attL 35922:35981|attR 50361:53754

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN16100.1\|22448_23729_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	5.0e-95	52.7
AUN16101.1\|24976_26140_-\|integrase	site-specific integrase	A0A2I7SCV1	Paenibacillus_phage	1.9e-29	27.8
AUN16102.1\|26222_26786_-	hypothetical protein	NA	NA	NA	NA
AUN16103.1\|26922_27123_+	hypothetical protein	NA	NA	NA	NA
AUN16104.1\|27237_27426_+	hypothetical protein	NA	NA	NA	NA
AUN16105.1\|27558_28236_+	hypothetical protein	NA	NA	NA	NA
AUN16106.1\|28239_28524_+	hypothetical protein	NA	NA	NA	NA
AUN16107.1\|28516_29857_+	hypothetical protein	Q8SDW1	Staphylococcus_phage	4.7e-27	27.8
AUN16108.1\|30010_30322_+	hypothetical protein	NA	NA	NA	NA
AUN16109.1\|30337_30532_+	hypothetical protein	NA	NA	NA	NA
AUN16110.1\|30655_31465_+	hypothetical protein	NA	NA	NA	NA
AUN16111.1\|31663_32872_+\|portal	portal protein	A0A1L2BY94	Clostridium_phage	9.0e-62	37.2
AUN16112.1\|32858_33419_+	peptidase U35	A0A1Q1PVX3	Staphylococcus_phage	7.9e-13	29.8
AUN16113.1\|33422_34658_+\|capsid	phage capsid protein	A0A1L2BY91	Clostridium_phage	1.4e-17	24.2
AUN16114.1\|34715_34976_+	DNA packaging protein	A0A2H4J6E5	uncultured_Caudovirales_phage	6.7e-07	33.3
AUN16115.1\|34979_35363_+	hypothetical protein	NA	NA	NA	NA
AUN16116.1\|35378_35921_+\|integrase	integrase	A0A1B1P746	Bacillus_phage	9.9e-37	47.5
35922:35981	attL	NA	NA	NA	NA
AUN16117.1\|36094_36400_+	HNH endonuclease	R9TNN2	Paenibacillus_phage	9.0e-19	48.9
AUN16118.1\|36494_36833_+	hypothetical protein	A0A290GJQ7	Caldibacillus_phage	1.4e-17	43.5
AUN16119.1\|36834_38484_+\|terminase	terminase	A0A290GJW3	Caldibacillus_phage	7.2e-163	52.1
AUN16120.1\|38528_38858_+\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
AUN16121.1\|38868_39126_+	hypothetical protein	NA	NA	NA	NA
AUN16122.1\|39416_40580_-\|integrase	site-specific integrase	A0A2I7SCV1	Paenibacillus_phage	1.9e-29	27.8
AUN16123.1\|40662_41226_-	hypothetical protein	NA	NA	NA	NA
AUN16124.1\|41362_41563_+	hypothetical protein	NA	NA	NA	NA
AUN16125.1\|41676_41865_+	hypothetical protein	NA	NA	NA	NA
AUN16126.1\|41997_42675_+	hypothetical protein	NA	NA	NA	NA
AUN16127.1\|42678_42963_+	hypothetical protein	NA	NA	NA	NA
AUN16128.1\|42955_44296_+	hypothetical protein	Q8SDW1	Staphylococcus_phage	4.7e-27	27.8
AUN16129.1\|44449_44761_+	hypothetical protein	NA	NA	NA	NA
AUN16130.1\|44776_44971_+	hypothetical protein	NA	NA	NA	NA
AUN16131.1\|45094_45904_+	hypothetical protein	NA	NA	NA	NA
AUN16132.1\|46102_47311_+\|portal	portal protein	A0A1L2BY94	Clostridium_phage	9.0e-62	37.2
AUN16133.1\|47297_47858_+	peptidase U35	A0A1Q1PVX3	Staphylococcus_phage	7.9e-13	29.8
AUN16134.1\|47861_49097_+\|capsid	phage capsid protein	A0A1L2BY91	Clostridium_phage	1.4e-17	24.2
AUN16135.1\|49154_49415_+	DNA packaging protein	A0A2H4J6E5	uncultured_Caudovirales_phage	6.7e-07	33.3
AUN16136.1\|49418_49802_+	hypothetical protein	NA	NA	NA	NA
AUN16137.1\|49817_50360_+\|integrase	integrase	A0A1B1P746	Bacillus_phage	9.9e-37	47.5
AUN16138.1\|50533_50839_+	HNH endonuclease	R9TNN2	Paenibacillus_phage	9.0e-19	48.9
AUN16139.1\|50933_51272_+	hypothetical protein	A0A290GJQ7	Caldibacillus_phage	1.4e-17	43.5
AUN16140.1\|51273_52923_+\|terminase	terminase	A0A290GJW3	Caldibacillus_phage	7.2e-163	52.1
AUN16141.1\|52967_53297_+\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
AUN16142.1\|53307_53565_+	hypothetical protein	NA	NA	NA	NA
AUN16143.1\|53788_54676_-	phosphatidylserine decarboxylase	A0A2K9L6Z6	Tupanvirus	5.5e-16	29.5
50361:53754	attR	NA	NA	NA	NA
AUN16144.1\|54778_56377_-	protein kinase	A0A0P0CRP3	Ostreococcus_lucimarinus_virus	2.1e-42	29.1

DBSCAN-SWA_2

1752095 : 1759150

uncultured_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN17609.1\|1752095_1753040_-	decarboxylase	A0A1B0RXM1	Streptococcus_phage	3.2e-14	31.1
AUN17610.1\|1753654_1754650_+	2-hydroxyglutaryl-CoA dehydratase	NA	NA	NA	NA
AUN17611.1\|1754766_1755528_+	2-hydroxyglutaryl-CoA dehydratase	NA	NA	NA	NA
AUN17612.1\|1755545_1755977_+	6-carboxytetrahydropterin synthase QueD	A0A1U9WRB3	Streptococcus_virus	1.8e-12	33.1
AUN17613.1\|1755978_1756644_+	7-carboxy-7-deazaguanine synthase QueE	S4TZT1	uncultured_phage	6.5e-38	44.6
AUN17614.1\|1756647_1757238_+	GTP cyclohydrolase I FolE	S4U0J3	uncultured_phage	9.8e-46	54.5
AUN17615.1\|1757421_1758081_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	3.0e-59	51.2
AUN17616.1\|1758193_1759150_+	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	7.7e-16	33.5

DBSCAN-SWA_3

2441972 : 2490381

uncultured_Caudovirales_phage(35.42%)

terminase,tail,capsid,portal,integrase

attL 2437651:2437672|attR 2476975:2476996

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2437651:2437672	attL	NA	NA	NA	NA
AUN19628.1\|2441972_2442434_-	hypothetical protein	A0A0N9SGM1	Paenibacillus_phage	5.1e-26	41.9
AUN18191.1\|2442765_2443788_-	hypothetical protein	Q0SPG7	Clostridium_phage	4.5e-38	42.5
AUN18192.1\|2443822_2444239_-	hypothetical protein	D2XPZ9	Bacillus_virus	6.3e-23	42.2
AUN18193.1\|2444406_2444601_-	hypothetical protein	NA	NA	NA	NA
AUN18194.1\|2444766_2444973_-	hypothetical protein	NA	NA	NA	NA
AUN18195.1\|2445239_2445536_-	hypothetical protein	J9QEB9	Clostridium_phage	1.3e-14	46.5
AUN18196.1\|2445551_2446718_-\|tail	phage tail protein	A0A0A7RTQ0	Clostridium_phage	3.0e-62	55.8
AUN18197.1\|2446720_2447356_-	hypothetical protein	A0A2H4J1P4	uncultured_Caudovirales_phage	5.0e-72	65.6
AUN18198.1\|2447352_2448483_-	hypothetical protein	A0A2H4J7K8	uncultured_Caudovirales_phage	5.9e-124	63.6
AUN18199.1\|2448488_2448941_-	hypothetical protein	A0A2H4J4Q8	uncultured_Caudovirales_phage	1.6e-64	76.3
AUN18200.1\|2448933_2449266_-	hypothetical protein	A0A2H4J746	uncultured_Caudovirales_phage	1.3e-34	68.9
AUN18201.1\|2449249_2450218_-	XkdQ	A0A2H4J063	uncultured_Caudovirales_phage	9.5e-115	65.3
AUN19629.1\|2450217_2450871_-\|portal	phage portal protein	A0A2H4J045	uncultured_Caudovirales_phage	2.2e-59	68.3
AUN18202.1\|2450937_2451450_-	hypothetical protein	A0A2H4J333	uncultured_Caudovirales_phage	1.2e-28	56.0
AUN18203.1\|2451503_2454482_-\|tail	phage tail tape measure protein	A0A2H4J055	uncultured_Caudovirales_phage	1.0e-215	51.2
AUN18204.1\|2454482_2454629_-	hypothetical protein	NA	NA	NA	NA
AUN18205.1\|2454664_2455099_-	hypothetical protein	A0A2H4J883	uncultured_Caudovirales_phage	1.1e-54	74.8
AUN18206.1\|2455122_2455533_-\|portal	phage portal protein	A0A2H4J032	uncultured_Caudovirales_phage	8.8e-62	86.5
AUN18207.1\|2455545_2456952_-\|tail	phage tail sheath protein	A0A2H4J1N7	uncultured_Caudovirales_phage	1.1e-225	80.3
AUN18208.1\|2456951_2457143_-	hypothetical protein	A0A2H4J7J8	uncultured_Caudovirales_phage	5.2e-17	72.6
AUN18209.1\|2457153_2457975_-	hypothetical protein	A0A2H4J4Q0	uncultured_Caudovirales_phage	7.1e-119	74.0
AUN18210.1\|2457977_2458385_-	hypothetical protein	A0A2H4J736	uncultured_Caudovirales_phage	2.4e-51	70.1
AUN18211.1\|2458386_2458773_-	hypothetical protein	A0A2H4J057	uncultured_Caudovirales_phage	1.9e-42	65.4
AUN18212.1\|2458773_2459094_-	hypothetical protein	A0A2H4J040	uncultured_Caudovirales_phage	3.9e-25	57.4
AUN18213.1\|2459096_2459288_-	hypothetical protein	NA	NA	NA	NA
AUN18214.1\|2459344_2460397_-\|capsid	phage capsid protein	D9ZND6	Clostridium_phage	1.8e-87	50.6
AUN18215.1\|2460410_2460803_-	hypothetical protein	NA	NA	NA	NA
AUN18216.1\|2460823_2461438_-\|capsid	phage capsid protein	A0A0A7RW68	Clostridium_phage	3.8e-24	35.8
AUN18217.1\|2461653_2463312_-	exonuclease SbcC	A0A2H4J048	uncultured_Caudovirales_phage	1.0e-193	64.7
AUN18218.1\|2463311_2464838_-	hypothetical protein	D9ZNC8	Clostridium_phage	7.9e-140	53.1
AUN18219.1\|2464837_2466193_-\|terminase	terminase	A0A2P1JTW5	Anoxybacillus_phage	2.4e-156	64.5
AUN18220.1\|2466192_2466900_-	hypothetical protein	A0A0A8WFS6	Clostridium_phage	7.1e-51	51.1
AUN18221.1\|2466995_2467235_-	peptidase	NA	NA	NA	NA
AUN18222.1\|2467350_2467569_-	hypothetical protein	A0A0A7RTM8	Clostridium_phage	1.9e-10	57.1
AUN19630.1\|2467660_2468665_-	hypothetical protein	A0A0K2FHC7	Achromobacter_phage	1.1e-07	41.7
AUN18223.1\|2469309_2469747_-	hypothetical protein	NA	NA	NA	NA
AUN18224.1\|2469757_2469991_-	hypothetical protein	NA	NA	NA	NA
AUN18225.1\|2469992_2470397_-	hypothetical protein	A0A0E3Y4X1	Fusobacterium_phage	3.5e-10	36.8
AUN18226.1\|2470674_2470902_-	hypothetical protein	NA	NA	NA	NA
AUN18227.1\|2470922_2471750_-	DNA methylase	A7YGL3	Campylobacter_phage	8.6e-32	35.4
AUN19631.1\|2471764_2471980_-	hypothetical protein	NA	NA	NA	NA
AUN18228.1\|2471996_2472992_-\|integrase	integrase	B9UDL9	Salmonella_phage	4.9e-05	24.5
AUN18229.1\|2473708_2474098_-	hypothetical protein	NA	NA	NA	NA
AUN18230.1\|2474231_2474414_-	hypothetical protein	NA	NA	NA	NA
AUN18231.1\|2474474_2474780_-	hypothetical protein	NA	NA	NA	NA
AUN18232.1\|2474997_2475186_-	hypothetical protein	NA	NA	NA	NA
AUN18233.1\|2475231_2475405_-	hypothetical protein	NA	NA	NA	NA
AUN18234.1\|2475456_2475675_-	hypothetical protein	NA	NA	NA	NA
AUN18235.1\|2475698_2476046_-	hypothetical protein	A0A0A7RTL9	Clostridium_phage	1.4e-28	57.0
AUN18236.1\|2476048_2476453_-	hypothetical protein	D0R7I5	Paenibacillus_phage	4.8e-12	42.1
AUN18237.1\|2476603_2476969_-	hypothetical protein	A0A0A7RVR5	Clostridium_phage	3.8e-24	46.2
AUN18238.1\|2477045_2477759_-	hypothetical protein	A0A0A7RWW3	Clostridium_phage	5.1e-73	62.3
2476975:2476996	attR	NA	NA	NA	NA
AUN18239.1\|2477785_2478178_-	replication terminator protein	A0A0A7RUF3	Clostridium_phage	2.6e-34	58.5
AUN19632.1\|2478275_2478617_-	nucleotide pyrophosphohydrolase	R4T830	Halovirus	5.0e-10	55.4
AUN18240.1\|2478655_2478895_-	AbrB family transcriptional regulator	A0A0K2CZ86	Paenibacillus_phage	1.7e-20	60.3
AUN18241.1\|2478897_2479218_-	hypothetical protein	NA	NA	NA	NA
AUN18242.1\|2479219_2480098_-	hypothetical protein	NA	NA	NA	NA
AUN19633.1\|2480109_2480343_-	hypothetical protein	A0A0A7RTQ4	Clostridium_phage	2.4e-11	41.0
AUN19634.1\|2480365_2481169_-	DNA replication protein	A0A2K9V3L7	Faecalibacterium_phage	1.6e-35	35.1
AUN18243.1\|2481128_2482001_-	replication protein	Q7Y4K5	Streptococcus_phage	4.5e-39	40.8
AUN19635.1\|2482023_2482323_-	hypothetical protein	NA	NA	NA	NA
AUN18244.1\|2482608_2482755_-	hypothetical protein	NA	NA	NA	NA
AUN18245.1\|2482757_2483618_-	hypothetical protein	E5DV80	Deep-sea_thermophilic_phage	3.1e-56	47.1
AUN18246.1\|2483629_2484115_-	hypothetical protein	A0A059T5F1	Listeria_phage	2.4e-26	44.7
AUN18247.1\|2484803_2485013_-	hypothetical protein	NA	NA	NA	NA
AUN18248.1\|2485024_2485813_-	oxidoreductase	A0A0E3T9K5	Staphylococcus_phage	2.4e-87	64.1
AUN18249.1\|2485866_2486088_-	transcriptional regulator	NA	NA	NA	NA
AUN18250.1\|2486220_2486679_+	transcriptional regulator	S6C481	Thermus_phage	2.2e-05	31.1
AUN18251.1\|2486725_2487160_+	hypothetical protein	D6R412	Bacillus_phage	4.8e-26	47.1
AUN18252.1\|2488758_2490381_+	resolvase	A0A1L2BY67	Clostridium_phage	3.5e-93	37.2

DBSCAN-SWA_4

3021618 : 3031052

Synechococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN18727.1\|3021618_3023118_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.2e-69	46.9
AUN18728.1\|3023331_3023949_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.6e-25	40.6
AUN18729.1\|3024076_3025072_-	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	9.9e-67	43.7
AUN18730.1\|3025132_3026581_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.5e-58	35.1
AUN18731.1\|3026672_3027377_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	2.3e-41	41.7
AUN18732.1\|3027376_3027856_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.2e-27	49.4
AUN18733.1\|3028481_3031052_-	selenium-dependent xanthine dehydrogenase	A0A0P0IVM8	Acinetobacter_phage	1.3e-09	32.4

DBSCAN-SWA_5

3168438 : 3200367

Clostridium_phage(74.07%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN18859.1\|3168438_3171066_-	DNA polymerase I	F8WQ35	Bacillus_phage	1.9e-64	35.6
AUN18860.1\|3171083_3172208_-	chorismate synthase	A0A291AU41	Pandoravirus	2.9e-30	28.5
AUN18861.1\|3172606_3173386_-	N-acetylmuramoyl-L-alanine amidase	A0A2H4J8A3	uncultured_Caudovirales_phage	1.2e-88	63.4
AUN18862.1\|3173532_3173727_-	hypothetical protein	NA	NA	NA	NA
AUN18863.1\|3173745_3174000_-	hypothetical protein	A0A0A7RTX0	Clostridium_phage	4.8e-26	70.9
AUN19654.1\|3174155_3174965_-	hypothetical protein	A0A0A7RU33	Clostridium_phage	5.3e-26	34.7
AUN18864.1\|3175060_3176404_-	cell adhesion protein	A0A0A7RU33	Clostridium_phage	1.6e-14	37.9
AUN18865.1\|3176417_3177197_-	hypothetical protein	NA	NA	NA	NA
AUN18866.1\|3178106_3179192_-	signal peptidase II	A0A0A7RU66	Clostridium_phage	5.1e-141	69.8
AUN18867.1\|3179203_3180202_-	hypothetical protein	A0A0A7RW91	Clostridium_phage	1.1e-142	73.5
AUN18868.1\|3180213_3180489_-	hypothetical protein	A0A223LE82	Bacillus_phage	5.1e-05	38.8
AUN18869.1\|3180491_3182513_-	hypothetical protein	A0A0A7RU09	Clostridium_phage	3.2e-56	48.1
AUN18870.1\|3182524_3184033_-	hypothetical protein	A0A0A7RU28	Clostridium_phage	3.6e-92	37.5
AUN18871.1\|3184055_3185033_-	hypothetical protein	A0A0A7RU61	Clostridium_phage	9.3e-110	59.9
AUN18872.1\|3185034_3186384_-	hypothetical protein	A0A0A7RW86	Clostridium_phage	2.1e-75	74.6
AUN18873.1\|3186398_3186740_-	hypothetical protein	A0A0A7S0S4	Clostridium_phage	1.6e-16	55.7
AUN18874.1\|3186752_3187838_-	hypothetical protein	NA	NA	NA	NA
AUN18875.1\|3187824_3188259_-	hypothetical protein	NA	NA	NA	NA
AUN18876.1\|3188271_3189675_-	hypothetical protein	A0A0A7RU22	Clostridium_phage	6.9e-05	42.4
AUN19655.1\|3189838_3190006_-	hypothetical protein	A0A0A7RW80	Clostridium_phage	1.9e-15	70.4
AUN18877.1\|3190040_3190457_-	esterase	A0A0A7S0S0	Clostridium_phage	9.0e-46	71.2
AUN18878.1\|3190471_3191359_-	hypothetical protein	A0A0A7RTZ9	Clostridium_phage	2.6e-119	74.7
AUN18879.1\|3191363_3191783_-	hypothetical protein	A0A0A7RU17	Clostridium_phage	1.8e-57	72.7
AUN18880.1\|3191788_3192136_-	hypothetical protein	A0A0A7RU51	Clostridium_phage	1.9e-33	60.7
AUN18881.1\|3192140_3192506_-	hypothetical protein	A0A0A7RW73	Clostridium_phage	5.0e-32	56.2
AUN18882.1\|3192505_3192790_-	hypothetical protein	A0A0A7S0R4	Clostridium_phage	1.0e-24	60.2
AUN18883.1\|3193475_3193997_-	hypothetical protein	A0A0A7RVS1	Clostridium_phage	1.1e-35	50.0
AUN18884.1\|3194109_3194430_-	hypothetical protein	NA	NA	NA	NA
AUN18885.1\|3194486_3195335_-	DNA replication protein	A0A2K9V3L7	Faecalibacterium_phage	4.0e-32	34.8
AUN18886.1\|3195276_3196182_-	hypothetical protein	A8ASN4	Listeria_phage	9.4e-40	39.5
AUN18887.1\|3196275_3196488_-	transcriptional regulator	NA	NA	NA	NA
AUN18888.1\|3196549_3196759_-	transcriptional regulator	NA	NA	NA	NA
AUN18889.1\|3196950_3197361_+	transcriptional regulator	A0A0A7RUJ5	Clostridium_phage	1.0e-09	56.2
AUN18890.1\|3197662_3197812_+	hypothetical protein	NA	NA	NA	NA
AUN18891.1\|3198879_3200367_+	membrane-bound O-acyltransferase family protein	A0A125RNP0	Pseudomonas_phage	4.3e-66	38.3

DBSCAN-SWA_6

3332817 : 3394398

Clostridium_phage(59.46%)

terminase,bacteriocin,head,tail,capsid,portal,integrase,protease,tRNA

attL 3334171:3334188|attR 3397534:3397551

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN19007.1\|3332817_3335463_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	2.8e-177	43.3
3334171:3334188	attL	NA	NA	NA	NA
AUN19008.1\|3335483_3335990_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AUN19009.1\|3336631_3336919_-	hypothetical protein	NA	NA	NA	NA
AUN19010.1\|3336887_3337271_-	hypothetical protein	NA	NA	NA	NA
AUN19011.1\|3337348_3338461_-\|bacteriocin	bacteriocin ABC transporter	NA	NA	NA	NA
AUN19012.1\|3338447_3338945_-	hypothetical protein	NA	NA	NA	NA
AUN19013.1\|3338931_3341214_-	ABC transporter permease	W8CYL7	Bacillus_phage	5.7e-41	27.9
AUN19014.1\|3341628_3342657_+	nitrate ABC transporter substrate-binding protein	NA	NA	NA	NA
AUN19015.1\|3342662_3342845_-	hypothetical protein	NA	NA	NA	NA
AUN19016.1\|3343006_3347299_-	2-hydroxyglutaryl-CoA dehydratase	NA	NA	NA	NA
AUN19017.1\|3347620_3348382_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.0e-31	39.5
AUN19018.1\|3348378_3349182_+	sulfonate ABC transporter permease	NA	NA	NA	NA
AUN19019.1\|3349325_3349673_+	hypothetical protein	NA	NA	NA	NA
AUN19020.1\|3349795_3350971_-	transglutaminase	NA	NA	NA	NA
AUN19021.1\|3350995_3351931_-	recombination regulator RecX	NA	NA	NA	NA
AUN19022.1\|3351952_3353182_-	peptidase M16	G3MBJ8	Bacillus_virus	3.4e-32	28.5
AUN19023.1\|3353402_3353906_+	transporter	E7DN70	Pneumococcus_phage	1.7e-14	40.8
AUN19024.1\|3354103_3354682_+	flavin reductase	NA	NA	NA	NA
AUN19025.1\|3355078_3355315_+	transcriptional regulator	A0A0A7RUG5	Clostridium_phage	1.8e-22	67.9
AUN19026.1\|3355386_3355665_+	transcriptional regulator	A0A0A7S0F1	Clostridium_phage	6.0e-38	89.1
AUN19027.1\|3355699_3356287_-	hypothetical protein	A0A0A7RUM7	Clostridium_phage	2.1e-08	30.4
AUN19028.1\|3356409_3356655_-	hypothetical protein	NA	NA	NA	NA
AUN19029.1\|3356639_3356831_-	hypothetical protein	A0A0A7RTH9	Clostridium_phage	3.5e-13	70.9
AUN19030.1\|3357578_3358340_-	N-acetylmuramoyl-L-alanine amidase	I1TJX3	Clostridium_phage	9.0e-52	56.0
AUN19657.1\|3358379_3358574_-	hypothetical protein	NA	NA	NA	NA
AUN19031.1\|3358590_3358845_-	hypothetical protein	A0A0A7RTX0	Clostridium_phage	1.1e-25	69.6
AUN19032.1\|3358952_3359873_-	hypothetical protein	NA	NA	NA	NA
AUN19033.1\|3359891_3360542_-	hypothetical protein	NA	NA	NA	NA
AUN19034.1\|3360534_3361023_-	hypothetical protein	NA	NA	NA	NA
AUN19035.1\|3361373_3361631_-	hypothetical protein	NA	NA	NA	NA
AUN19036.1\|3361649_3361802_-	hypothetical protein	NA	NA	NA	NA
AUN19037.1\|3361958_3362426_-	hypothetical protein	NA	NA	NA	NA
AUN19038.1\|3362737_3363037_-	hypothetical protein	B6SBV1	Clostridium_virus	3.5e-15	50.0
AUN19039.1\|3363047_3364292_-	hypothetical protein	E2ELJ8	Clostridium_phage	1.3e-71	52.3
AUN19040.1\|3364296_3365373_-	hypothetical protein	E2ELJ7	Clostridium_phage	1.1e-124	60.7
AUN19041.1\|3365376_3366243_-\|tail	phage tail protein	E2ELJ6	Clostridium_phage	1.5e-95	61.2
AUN19042.1\|3366256_3371380_-\|tail	phage tail tape measure protein	E2ELJ5	Clostridium_phage	1.4e-15	63.2
AUN19043.1\|3371420_3371600_-	hypothetical protein	NA	NA	NA	NA
AUN19044.1\|3371861_3372143_-	hypothetical protein	E2ELJ2	Clostridium_phage	6.5e-16	48.4
AUN19045.1\|3372172_3372751_-	hypothetical protein	NA	NA	NA	NA
AUN19046.1\|3372750_3373095_-	hypothetical protein	E2ELJ0	Clostridium_phage	3.7e-21	46.9
AUN19047.1\|3373176_3373563_-	hypothetical protein	E2ELI9	Clostridium_phage	8.7e-27	50.0
AUN19048.1\|3373555_3373915_-\|head,tail	head-tail adaptor protein	A0A2I7SC03	Paenibacillus_phage	9.3e-07	35.7
AUN19049.1\|3373865_3374165_-	hypothetical protein	A0A1B1P751	Bacillus_phage	3.8e-06	38.6
AUN19050.1\|3374174_3375320_-\|capsid	phage capsid protein	E2ELI5	Clostridium_phage	2.1e-124	58.6
AUN19051.1\|3375319_3376063_-\|protease	Clp protease	Q8W605	Listeria_phage	8.2e-50	46.7
AUN19052.1\|3376067_3377201_-\|portal	phage portal protein	E2ELI3	Clostridium_phage	6.2e-89	42.6
AUN19053.1\|3377225_3378872_-\|terminase	terminase	E2ELI2	Clostridium_phage	4.2e-147	48.6
AUN19054.1\|3378855_3379350_-	RNA polymerase subunit sigma-70	A0A1B1P762	Bacillus_phage	7.5e-15	41.9
AUN19055.1\|3379521_3379830_-	HNH endonuclease	A0A1S7FZ53	Listeria_phage	1.2e-18	48.5
AUN19056.1\|3379841_3380261_-	non-transporter ABC protein	NA	NA	NA	NA
AUN19057.1\|3380262_3380622_-	hypothetical protein	NA	NA	NA	NA
AUN19058.1\|3380831_3381023_-	hypothetical protein	NA	NA	NA	NA
AUN19059.1\|3381050_3381359_-	transglycosylase	NA	NA	NA	NA
AUN19060.1\|3381514_3382060_-\|integrase	site-specific integrase	E2ELN7	Clostridium_phage	9.6e-56	60.1
AUN19658.1\|3382060_3382276_-	hypothetical protein	NA	NA	NA	NA
AUN19061.1\|3382460_3382889_-	hypothetical protein	NA	NA	NA	NA
AUN19062.1\|3383044_3383335_-	hypothetical protein	NA	NA	NA	NA
AUN19063.1\|3383327_3383480_-	hypothetical protein	A0A0A7RTX2	Clostridium_phage	9.6e-06	50.0
AUN19064.1\|3383491_3384487_-\|integrase	integrase	B9UDL9	Salmonella_phage	2.8e-05	25.5
AUN19065.1\|3384850_3385900_-	nucleoid-associated bacterial protein	J9QE81	Clostridium_phage	1.7e-37	29.3
AUN19066.1\|3385937_3386165_-	hypothetical protein	NA	NA	NA	NA
AUN19067.1\|3386206_3386389_-	hypothetical protein	NA	NA	NA	NA
AUN19068.1\|3386450_3386636_-	hypothetical protein	NA	NA	NA	NA
AUN19069.1\|3386704_3386887_-	hypothetical protein	NA	NA	NA	NA
AUN19070.1\|3386928_3387384_-	hypothetical protein	R9TMG2	Paenibacillus_phage	4.5e-06	54.3
AUN19071.1\|3387795_3388116_-	hypothetical protein	NA	NA	NA	NA
AUN19072.1\|3388155_3388452_-	hypothetical protein	NA	NA	NA	NA
AUN19073.1\|3388468_3389230_-	MerR family transcriptional regulator	M9Q1J4	Clostridium_phage	8.7e-55	48.2
AUN19074.1\|3389171_3390014_-	hypothetical protein	A0A0A7S128	Clostridium_phage	1.1e-53	71.6
AUN19075.1\|3390083_3390305_-	hypothetical protein	NA	NA	NA	NA
AUN19076.1\|3390553_3390901_+	hypothetical protein	NA	NA	NA	NA
AUN19077.1\|3391034_3391796_-	hypothetical protein	A0A288WG93	Bacillus_phage	7.4e-54	46.3
AUN19078.1\|3392025_3392238_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AUN19079.1\|3392454_3392835_+	hypothetical protein	A0A139ZPI6	Marinitoga_camini_virus	3.7e-06	47.5
AUN19080.1\|3392859_3394398_+	hypothetical protein	A0A1L2BY67	Clostridium_phage	5.3e-83	38.8
3397534:3397551	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP014152

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1603 : 10460

Bathycoccus_sp._RCC1105_virus(16.67%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN19669.1\|1603_3328_+	cell division protein FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	1.1e-86	39.6
AUN19670.1\|3609_4416_-	hypothetical protein	A0A172WZB4	Catopsilia_pomona_nucleopolyhedrovirus	1.9e-07	23.9
AUN19671.1\|4761_5319_+\|protease	spore protease YyaC	G3M9W0	Bacillus_virus	2.9e-23	45.9
AUN19672.1\|5373_5718_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	6.8e-15	40.6
AUN19673.1\|5742_7185_+\|transposase	transposase	A0A0H3UZK2	Geobacillus_virus	1.3e-147	56.7
AUN19674.1\|7568_8024_+	hypothetical protein	NA	NA	NA	NA
AUN19675.1\|8123_8912_+	hypothetical protein	NA	NA	NA	NA
AUN19676.1\|9132_9348_+	30S ribosomal protein S23	NA	NA	NA	NA
AUN19677.1\|9409_9640_+	glutamate racemase	NA	NA	NA	NA
AUN19678.1\|9670_9853_+	hypothetical protein	NA	NA	NA	NA
AUN19899.1\|9923_10460_+	hypothetical protein	L0LC12	Bacillus_phage	5.1e-09	33.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP014151

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP014152

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection