CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP025936	Vibrio cholerae strain A1552 chromosome 1, complete sequence	0 crisprs	DinG,csa3,DEDDh,cas3,WYL,csx1,RT	0	0	8	0
CP025937	Vibrio cholerae strain A1552 chromosome 2, complete sequence	0 crisprs	PD-DExK,csa3,cas3	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

275762 : 284380

Vibrio_phage(33.33%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUR68780.1\|275762_276939_+	DDE domain-containing protein	Q716C2	Shigella_phage	8.6e-118	65.1
AUR68781.1\|276975_278217_-	DUF4102 domain-containing protein	A0A1V0E8G8	Vibrio_phage	9.1e-110	47.3
AUR68782.1\|278602_280480_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.5e-34	32.9
AUR68783.1\|280578_282342_-	DNA primase	A0A1S5RG58	Helicobacter_phage	1.1e-44	30.7
AUR68784.1\|282431_282875_-	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	3.7e-29	49.3
AUR68785.1\|282904_283120_-	30S ribosomal protein S21	NA	NA	NA	NA
AUR68786.1\|283360_284380_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	2.6e-107	57.4

DBSCAN-SWA_2

290510 : 297767

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUR68797.1\|290510_291302_+	5'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	8.4e-69	51.6
AUR68798.1\|291294_291921_+	protein-L-isoaspartate O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.0e-36	52.1
AUR68799.1\|291920_292850_+	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	7.7e-05	34.7
AUR68800.1\|292923_293931_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.0e-35	34.2
AUR68801.1\|294023_296612_-	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	2.2e-33	23.0
AUR68802.1\|296879_297767_-	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	4.1e-56	41.1

DBSCAN-SWA_3

529390 : 536583

Faustovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUR68993.1\|529390_530605_+	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	1.1e-32	30.5
AUR68994.1\|530641_531025_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	78.2
AUR68995.1\|531085_531409_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	3.0e-25	50.5
AUR68996.1\|531457_531973_+	co-chaperone protein HscB	NA	NA	NA	NA
AUR68997.1\|531996_533847_+	chaperone protein HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	5.3e-106	41.1
AUR68998.1\|533860_534199_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
AUR68999.1\|534247_534442_+	Fe-S assembly protein IscX	NA	NA	NA	NA
AUR69000.1\|534661_535951_+	peptidase B	Q6GYZ8	Mycoplasma_phage	1.7e-34	34.3
AUR69001.1\|536154_536583_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.0e-20	38.4

DBSCAN-SWA_4

1275586 : 1308204

Vibrio_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUR69643.1\|1275586_1277749_-	lipid A ABC transporter ATP-binding protein/permease MsbA	W8CYL7	Bacillus_phage	5.0e-39	27.1
AUR69644.1\|1278106_1278466_+	peptide chain release factor 1	NA	NA	NA	NA
AUR69645.1\|1278491_1278953_+	toxin-activating lysine-acyltransferase RtxC	NA	NA	NA	NA
AUR69646.1\|1278937_1292614_+	multifunctional autoprocessing toxin RtxA	B3Y8K3	Vibrio_virus	8.4e-07	100.0
AUR69647.1\|1292981_1293206_-	RstC protein	U5TMI6	Satellite_phage	1.1e-34	100.0
AUR69648.1\|1293299_1293674_-	hypothetical protein	B9V3G5	Vibrio_virus	1.2e-68	100.0
AUR69649.1\|1293651_1294731_-	replication initiation factor family protein	U5TQR3	Satellite_phage	2.2e-213	100.0
AUR69650.1\|1294856_1295195_+	XRE family transcriptional regulator	U5TNA1	Satellite_phage	2.6e-51	96.4
AUR69651.1\|1295546_1295699_+	lipoate--protein ligase	B1B6U1	Vibrio_virus	4.0e-20	100.0
AUR69652.1\|1295807_1296182_-	enterotoxin	Q77DH7	Vibrio_virus	7.8e-65	100.0
AUR69653.1\|1296178_1296955_-	enterotoxin	A0A142I6Y0	Vibrio_phage	1.3e-151	100.0
AUR69654.1\|1297053_1298253_-	Zona occludens toxin	A0A142I6Z1	Vibrio_phage	5.3e-240	100.0
AUR69655.1\|1298249_1298543_-	hypothetical protein	A0A0F6YNQ7	Vibrio_phage	3.7e-46	100.0
AUR69656.1\|1298539_1299823_-	septation ring formation regulator EzrA	A0A142I701	Vibrio_phage	9.1e-222	100.0
AUR69657.1\|1299833_1300082_-	colonization factor	A0A0N7F140	Vibrio_phage	8.8e-33	100.0
AUR69658.1\|1300217_1300598_-	hypothetical protein	A0A0N9HJ67	Vibrio_phage	4.0e-69	100.0
AUR69659.1\|1300575_1301655_-	replication initiation factor family protein	U5TQR3	Satellite_phage	2.2e-213	100.0
AUR69660.1\|1301780_1302119_+	transcriptional regulator	U5TNA1	Satellite_phage	7.3e-54	100.0
AUR69661.1\|1302459_1302612_+	lipoate--protein ligase	B1B6U1	Vibrio_virus	2.0e-19	98.0
AUR69662.1\|1302608_1303193_-	DNA-binding protein	E3U9I9	Vibrio_phage	6.4e-114	100.0
AUR69663.1\|1303185_1303353_-	helicase	E3U9J0	Vibrio_phage	2.3e-13	100.0
AUR69664.1\|1303430_1304123_-	XRE family transcriptional regulator	NA	NA	NA	NA
AUR69665.1\|1304252_1304537_-	hypothetical protein	NA	NA	NA	NA
AUR69666.1\|1304541_1306110_-	replication protein	A7BJY2	Enterobacteria_phage	2.7e-58	32.3
AUR69667.1\|1306271_1306838_+	XRE family transcriptional regulator	NA	NA	NA	NA
AUR69668.1\|1307265_1307430_+	N-acetyl-gamma-glutamyl-phosphate reductase	NA	NA	NA	NA
AUR69669.1\|1307876_1308044_-	hypothetical protein	NA	NA	NA	NA
AUR69670.1\|1308036_1308204_-	helicase	E3U9J0	Vibrio_phage	2.3e-13	100.0

DBSCAN-SWA_5

1311997 : 1362203

Vibrio_phage(46.67%)

protease,transposase,tail,terminase,portal,capsid,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUR69675.1\|1311997_1313219_+\|transposase	IS3-like element ISVch4 family transposase	Q716C2	Shigella_phage	1.5e-117	65.1
AUR69676.1\|1313386_1313551_+	N-acetyl-gamma-glutamyl-phosphate reductase	NA	NA	NA	NA
AUR69677.1\|1314128_1314488_-	hypothetical protein	E3U9J1	Vibrio_phage	7.6e-09	100.0
AUR69678.1\|1314598_1314931_-	DUF3634 domain-containing protein	NA	NA	NA	NA
AUR69679.1\|1314935_1315445_-	macrodomain Ter protein MatP	NA	NA	NA	NA
AUR69680.1\|1315401_1317198_+\|protease	ATP-dependent protease LonB	NA	NA	NA	NA
AUR69681.1\|1317262_1317781_+	beta-hydroxydecanoyl-ACP dehydratase	NA	NA	NA	NA
AUR69682.1\|1317863_1318037_-	ribosome modulation factor	NA	NA	NA	NA
AUR69683.1\|1318204_1319899_-	DUF3466 domain-containing protein	NA	NA	NA	NA
AUR69684.1\|1319904_1321824_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	7.6e-55	29.7
AUR69685.1\|1321801_1322044_-	glutaredoxin family protein	NA	NA	NA	NA
AUR69686.1\|1322052_1324179_-	ribosomal RNA large subunit methyltransferase K/L	NA	NA	NA	NA
AUR69687.1\|1324638_1325181_-	cell division protein ZapC	NA	NA	NA	NA
AUR69688.1\|1325335_1326346_-	dihydroorotate dehydrogenase (quinone)	NA	NA	NA	NA
AUR69689.1\|1326419_1331261_-	NAD-glutamate dehydrogenase	NA	NA	NA	NA
AUR69690.1\|1331449_1331686_-	DUF2835 domain-containing protein	NA	NA	NA	NA
AUR69691.1\|1331719_1334344_-	aminopeptidase N	NA	NA	NA	NA
AUR71195.1\|1334416_1334653_-	MarR family transcriptional regulator	NA	NA	NA	NA
AUR69692.1\|1335601_1336114_+	hypothetical protein	NA	NA	NA	NA
AUR71196.1\|1336430_1337696_+	ATP-binding protein	NA	NA	NA	NA
AUR69693.1\|1337697_1338120_+	hypothetical protein	NA	NA	NA	NA
AUR69694.1\|1338183_1338549_-	peptidase M15	A0A2I7RAT1	Vibrio_phage	8.7e-37	60.3
AUR69695.1\|1338532_1339090_-	hypothetical protein	NA	NA	NA	NA
AUR69696.1\|1339089_1340097_-	radical SAM protein	NA	NA	NA	NA
AUR69697.1\|1340113_1340479_-	hypothetical protein	C8ZKF3	Pseudomonas_phage	1.8e-05	46.2
AUR69698.1\|1340479_1346422_-	fibronectin type III domain-containing protein	M4MHT9	Vibrio_phage	2.0e-98	30.9
AUR69699.1\|1346425_1346821_-	hypothetical protein	NA	NA	NA	NA
AUR69700.1\|1346823_1347363_-	hypothetical protein	M4MD40	Vibrio_phage	4.5e-21	35.1
AUR69701.1\|1347373_1347955_-	hypothetical protein	NA	NA	NA	NA
AUR69702.1\|1347956_1350269_-\|tail	phage tail tape measure protein	A0A1Q1PW43	Pseudoalteromonas_phage	4.4e-09	22.6
AUR69703.1\|1350285_1350576_-	hypothetical protein	NA	NA	NA	NA
AUR69704.1\|1350620_1350956_-	hypothetical protein	NA	NA	NA	NA
AUR69705.1\|1351008_1351479_-	hypothetical protein	NA	NA	NA	NA
AUR71197.1\|1351492_1351816_-	hypothetical protein	NA	NA	NA	NA
AUR69706.1\|1351863_1352475_-	hypothetical protein	NA	NA	NA	NA
AUR69707.1\|1352461_1352809_-	hypothetical protein	NA	NA	NA	NA
AUR69708.1\|1352820_1353372_-	hypothetical protein	A0A2I7QU98	Vibrio_phage	8.9e-09	28.0
AUR69709.1\|1353386_1354577_-\|capsid	phage major capsid protein	M4MA06	Vibrio_phage	1.3e-36	33.3
AUR69710.1\|1354675_1355524_-\|head,protease	HK97 family phage prohead protease	Q6JIM8	Burkholderia_virus	7.0e-29	39.1
AUR69711.1\|1355486_1356812_-\|portal	phage portal protein	M4MHV5	Vibrio_phage	1.2e-75	38.9
AUR69712.1\|1356821_1358582_-\|terminase	terminase large subunit	A0A0K1LKI4	Staphylococcus_phage	1.1e-81	35.9
AUR69713.1\|1358590_1358773_-	hypothetical protein	NA	NA	NA	NA
AUR69714.1\|1358772_1358988_-	hypothetical protein	NA	NA	NA	NA
AUR69715.1\|1359015_1359696_-	hypothetical protein	NA	NA	NA	NA
AUR71199.1\|1359692_1360136_-	hypothetical protein	NA	NA	NA	NA
AUR71198.1\|1360278_1360689_-\|terminase	phage terminase small subunit P27 family	A0A1W6JP17	Morganella_phage	5.8e-05	31.6
AUR69716.1\|1361159_1361348_-	hypothetical protein	NA	NA	NA	NA
AUR69717.1\|1361558_1362203_+	antirestriction protein	G0YPX7	Erwinia_phage	1.1e-10	33.5

DBSCAN-SWA_6

1366858 : 1374585

Diadromus_pulchellus_ascovirus(14.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUR69723.1\|1366858_1367446_-	deoxyguanosine kinase	F2NYY4	Diadromus_pulchellus_ascovirus	2.1e-08	33.1
AUR69724.1\|1367465_1367735_-	hypothetical protein	NA	NA	NA	NA
AUR69725.1\|1367731_1367929_-	hypothetical protein	NA	NA	NA	NA
AUR69726.1\|1367939_1368533_-	deoxynucleoside kinase	A0A249Y6S3	Cherax_quadricarinatus_iridovirus	3.7e-08	30.0
AUR69727.1\|1368665_1368923_-	hypothetical protein	NA	NA	NA	NA
AUR69728.1\|1368919_1369204_-	hypothetical protein	A0A142K9B6	Gordonia_phage	3.9e-08	51.9
AUR69729.1\|1369386_1370247_-	exonuclease	F1D0G7	Vibrio_phage	3.1e-56	43.0
AUR69730.1\|1370440_1370872_-	tellurite resistance protein	Q1MVI3	Enterobacteria_phage	2.1e-29	47.9
AUR69731.1\|1370896_1372951_-	DNA polymerase	A0A0F7DD46	Delftia_phage	7.1e-144	40.8
AUR69732.1\|1372950_1374585_-	DNA primase	L7TLT7	Rhizobium_phage	1.6e-122	49.0

DBSCAN-SWA_7

1712201 : 1719101

Vibrio_phage(83.33%)

tail,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUR70020.1\|1712201_1712408_-	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	1.9e-09	51.9
AUR70021.1\|1712521_1712998_+	DNA repair protein RadC	NA	NA	NA	NA
AUR70022.1\|1713227_1713923_-	chemotaxis protein	A0A2I7S9D9	Vibrio_phage	1.2e-18	35.4
AUR70023.1\|1713919_1715097_-\|transposase	IS3-like element ISVch4 family transposase	Q716C2	Shigella_phage	1.5e-117	65.1
AUR70024.1\|1715139_1716180_-\|tail	phage tail tape measure protein	A0A2I7S9D9	Vibrio_phage	2.6e-126	72.5
AUR70025.1\|1716314_1716674_-	hypothetical protein	A0A2I7S9E0	Vibrio_phage	3.7e-40	67.8
AUR70026.1\|1716722_1717100_-	6-phospho-beta-glucosidase	NA	NA	NA	NA
AUR70027.1\|1717154_1717733_-	glyoxalase	NA	NA	NA	NA
AUR70028.1\|1717751_1718072_-	transcriptional regulator	NA	NA	NA	NA
AUR70029.1\|1718058_1718433_-	transcriptional regulator	NA	NA	NA	NA
AUR70030.1\|1718834_1719101_-	regulator of ribonuclease activity A	M1Q554	Vibrio_phage	1.4e-07	33.8

DBSCAN-SWA_8

2199197 : 2205814

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUR70467.1\|2199197_2199668_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	6.8e-34	48.7
AUR70468.1\|2199932_2201042_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.7e-64	39.8
AUR70469.1\|2201082_2201736_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-31	38.2
AUR70470.1\|2201740_2202844_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.3e-43	33.1
AUR70471.1\|2202869_2203319_-	transcriptional regulator NrdR	NA	NA	NA	NA
AUR70472.1\|2203418_2204672_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.0e-100	49.5
AUR70473.1\|2204680_2205814_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.4e-64	40.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage