CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP026227	Aeromonas sp. ASNIH7 plasmid pKPC-1ac6, complete sequence	0 crisprs	NA	0	0	3	0
CP026226	Aeromonas sp. ASNIH7 chromosome, complete genome	7 crisprs	DinG,c2c9_V-U4,cas14j,csa3,PD-DExK,WYL,TnsE_C,cas3,DEDDh,cas14i	0	0	15	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 13591

Escherichia_phage(33.33%)

integrase,transposase

attL 3229:3251|attR 26444:26466

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV19268.1\|1871_2609_-	cell wall hydrolase	NA	NA	NA	NA
AUV19269.1\|2619_3114_-	conjugal transfer protein TraL	NA	NA	NA	NA
3229:3251	attL	NA	NA	NA	NA
AUV19270.1\|3298_3688_+	hypothetical protein	NA	NA	NA	NA
AUV19271.1\|3707_3968_+	hypothetical protein	NA	NA	NA	NA
AUV19272.1\|3960_4356_+	XRE family transcriptional regulator	NA	NA	NA	NA
AUV19273.1\|4420_4990_-	recombinase family protein	E5FFF9	Burkholderia_phage	1.4e-41	51.6
AUV19274.1\|5278_6292_-\|integrase	integrase/recombinase	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.8
AUV19311.1\|6643_7198_+	aminoglycoside N-acetyltransferase AAC(6')-Ib4	NA	NA	NA	NA
AUV19275.1\|7285_7900_+	lysine transporter LysE	NA	NA	NA	NA
AUV19276.1\|8021_8366_+	elongation factor Tu	NA	NA	NA	NA
AUV19277.1\|8952_10272_+\|transposase	IS1182 family transposase ISKpn6	Q9MBP7	Staphylococcus_prophage	1.9e-12	24.2
AUV19278.1\|10521_11403_-	carbapenem-hydrolyzing class A beta-lactamase KPC-2	A0A1B0VBP7	Salmonella_phage	2.2e-73	52.2
AUV19279.1\|11789_12569_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	2.5e-89	61.8
AUV19280.1\|12565_13591_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.4e-87	50.3
26444:26466	attR	NA	NA	NA	NA

DBSCAN-SWA_2

21296 : 30984

Rhodobacter_phage(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV19285.1\|21296_23012_-\|transposase	transposase	M4T586	Rhodobacter_phage	2.2e-05	25.3
AUV19286.1\|23683_23980_+	addiction module antidote protein, HigA family	NA	NA	NA	NA
AUV19287.1\|24152_25532_+	replication protein	D2XQ07	Bacillus_virus	3.5e-09	23.0
AUV19288.1\|25591_25789_+	hypothetical protein	NA	NA	NA	NA
AUV19289.1\|26126_26405_+	hypothetical protein	NA	NA	NA	NA
AUV19290.1\|26515_26941_+	antirestriction protein	A0A2D0W8Z5	Bordetella_virus	8.1e-18	38.1
AUV19291.1\|27269_27566_+	transcriptional repressor protein KorC	NA	NA	NA	NA
AUV19292.1\|27570_28638_+	TraN	A0A0R6PHM5	Moraxella_phage	1.4e-34	35.7
AUV19293.1\|28767_29835_+	hypothetical protein	NA	NA	NA	NA
AUV19294.1\|29888_30227_+	transcriptional regulator	NA	NA	NA	NA
AUV19295.1\|30231_30984_+	ParA family protein	Q8JL10	Natrialba_phage	1.3e-10	30.6

DBSCAN-SWA_3

37046 : 39995

Idiomarinaceae_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV19299.1\|37046_39995_-	hypothetical protein	A0A088F8A2	Idiomarinaceae_phage	1.2e-19	31.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP026226

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CRISPR-Cas detection and classification

Crispr_ID: CP026226_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026226_1

345240-345362

Orphan

Consensus_repeat	Method
ATGCCTTAGCCGTTGAACTGACTGCCAATCTGTTTGTTGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026226_1

>merge|CP026226|1|345240-345362|CRISPRCasFinder
ATGCCTTAGCCGTTGAACTGACTGCCAATCTGTTTGTTGATGCCCATCTTGTTCATCTCAATCACCCTTGTTGCACCAACATGCCTTAGCCGTTGAACTGACTGCCAATCTGCTTGTTGATGC

>CP026226|1|1|345240-345362|CRISPRCasFinder
ATGCCTTAGCCGTTGAACTGACTGCCAATCTGTTTGTTGATGC	CCATCTTGTTCATCTCAATCACCCTTGTTGCACCAAC
ATGCCTTAGCCGTTGAACTGACTGCCAATCTGCTTGTTGATGC

Protein	Signature genes	Signature genes Name	Protein_function
CP026226.1\|AUV15454.1\|338427_339837_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|129983
CP026226.1\|AUV18979.1\|342381_342918_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237174
CP026226.1\|AUV15464.1\|354167_355481_+\|isocitrate-lyase	unknown	unknown	gnl\|CDD\|237893
CP026226.1\|AUV18978.1\|340975_342180_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|181829
CP026226.1\|AUV15455.1\|339846_340749_-\|homocysteine-S-methyltransferase-family-protein	unknown	unknown	gnl\|CDD\|376828
CP026226.1\|AUV15465.1\|355906_356650_-\|DnaA-inactivator-Hda	unknown	unknown	gnl\|CDD\|181224
CP026226.1\|AUV15452.1\|336572_337316_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
CP026226.1\|AUV15458.1\|345393_346212_-\|phosphate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|184582
CP026226.1\|AUV15459.1\|346316_347966_-\|phosphate-ABC-transporter,-permease-protein-PstA	unknown	unknown	gnl\|CDD\|227318
CP026226.1\|AUV15461.1\|350389_350938_-\|tRNA-adenosine(34)-deaminase-TadA	unknown	unknown	gnl\|CDD\|182786
CP026226.1\|AUV15453.1\|337484_338360_+\|sterol-desaturase-family-protein	unknown	unknown	gnl\|CDD\|225546
CP026226.1\|AUV15462.1\|351434_351659_-\|hypothetical-protein	unknown	unknown	unknown
CP026226.1\|AUV18977.1\|334587_335439_+\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270347
CP026226.1\|AUV15457.1\|344503_345214_-\|phosphate-transport-system-regulatory-protein-PhoU	unknown	unknown	gnl\|CDD\|182974
CP026226.1\|AUV15460.1\|347983_350221_-\|phosphate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226956
CP026226.1\|AUV15456.1\|342942_344262_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
CP026226.1\|AUV15451.1\|335511_336483_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
CP026226.1\|AUV15463.1\|352490_354098_+\|malate-synthase-A	unknown	unknown	gnl\|CDD\|236432
CP026226.1\|AUV15466.1\|356710_357739_-\|DUF2066-domain-containing-protein	unknown	unknown	gnl\|CDD\|378267
CP026226.1\|AUV15467.1\|357880_358507_-\|uracil-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234653

Protein	Function_ID	Function_description	E-value
CP026226.1\|AUV15454.1\|338427_339837_-\|amino-acid-permease	gnl\|CDD\|129983	TIGR00905, Arginine/ornithine_antiporter, transporter, basic amino acid/polyamine antiporter (APA) family. This family includes several families of antiporters that, rather commonly, are encoded next to decarboxylases that convert one of the antiporter substrates into the other. This arrangement allows a cycle that can remove proteins from the cytoplasm and thereby protect against acidic conditions. [Transport and binding proteins, Amino acids, peptides and amines].	1.62756e-158
CP026226.1\|AUV18979.1\|342381_342918_-\|hypothetical-protein	gnl\|CDD\|237174	PRK12696, flgH, flagellar basal body L-ring protein; Reviewed.	0.00270877
CP026226.1\|AUV15464.1\|354167_355481_+\|isocitrate-lyase	gnl\|CDD\|237893	PRK15063, PRK15063, isocitrate lyase; Provisional.	0
CP026226.1\|AUV18978.1\|340975_342180_+\|IS3-family-transposase	gnl\|CDD\|181829	PRK09409, PRK09409, IS2 transposase TnpB; Reviewed.	1.24633e-143
CP026226.1\|AUV15455.1\|339846_340749_-\|homocysteine-S-methyltransferase-family-protein	gnl\|CDD\|376828	pfam02574, S-methyl_trans, Homocysteine S-methyltransferase. This is a family of related homocysteine S-methyltransferases enzymes: 5-methyltetrahydrofolate--homocysteine S-methyltransferases also known EC:2.1.1.13; Betaine--homocysteine S-methyltransferase (vitamin B12 dependent), EC:2.1.1.5; and Homocysteine S-methyltransferase, EC:2.1.1.10,.	3.84363e-74
CP026226.1\|AUV15465.1\|355906_356650_-\|DnaA-inactivator-Hda	gnl\|CDD\|181224	PRK08084, PRK08084, DnaA inactivator Hda.	1.64583e-111
CP026226.1\|AUV15452.1\|336572_337316_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	4.38282e-156
CP026226.1\|AUV15458.1\|345393_346212_-\|phosphate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|184582	PRK14236, PRK14236, phosphate transporter ATP-binding protein; Provisional.	0
CP026226.1\|AUV15459.1\|346316_347966_-\|phosphate-ABC-transporter,-permease-protein-PstA	gnl\|CDD\|227318	COG4985, COG4985, ABC-type phosphate transport system, auxiliary component [Inorganic ion transport and metabolism].	3.87477e-93
CP026226.1\|AUV15461.1\|350389_350938_-\|tRNA-adenosine(34)-deaminase-TadA	gnl\|CDD\|182786	PRK10860, PRK10860, tRNA-specific adenosine deaminase; Provisional.	2.39326e-86
CP026226.1\|AUV15453.1\|337484_338360_+\|sterol-desaturase-family-protein	gnl\|CDD\|225546	COG3000, ERG3, Sterol desaturase [Lipid metabolism].	3.50865e-36
CP026226.1\|AUV15466.1\|356710_357739_-\|DUF2066-domain-containing-protein	gnl\|CDD\|378267	pfam09839, DUF2066, Uncharacterized protein conserved in bacteria (DUF2066). This domain, found in various prokaryotic proteins, has no known function.	1.22986e-64
CP026226.1\|AUV18977.1\|334587_335439_+\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270347	cd13629, PBP2_Dsm1740, Amino acid-binding domain of the type 2 periplasmic binding fold superfamily. This subfamily includes the periplasmic binding protein type II (BPBII). This domain is found in solute binding proteins that serve as initial receptors in the ABC transport, signal transduction and channel gating. The PBPII proteins share the same architecture as periplasmic binding proteins type I (PBPI), but have a different topology. They are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBPII proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the family includes ionotropic glutamate receptors and unorthodox sensor proteins involved in signal transduction.	3.54941e-133
CP026226.1\|AUV15457.1\|344503_345214_-\|phosphate-transport-system-regulatory-protein-PhoU	gnl\|CDD\|182974	PRK11115, PRK11115, phosphate signaling complex protein PhoU.	1.72056e-161
CP026226.1\|AUV15460.1\|347983_350221_-\|phosphate-ABC-transporter-permease	gnl\|CDD\|226956	COG4590, COG4590, ABC-type uncharacterized transport system, permease component [General function prediction only].	0
CP026226.1\|AUV15456.1\|342942_344262_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	6.99105e-135
CP026226.1\|AUV15451.1\|335511_336483_+\|ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.10291e-89
CP026226.1\|AUV15463.1\|352490_354098_+\|malate-synthase-A	gnl\|CDD\|236432	PRK09255, PRK09255, malate synthase; Validated.	0
CP026226.1\|AUV15467.1\|357880_358507_-\|uracil-phosphoribosyltransferase	gnl\|CDD\|234653	PRK00129, upp, uracil phosphoribosyltransferase; Reviewed.	3.08223e-134

>CP026226.1|AUV15457.1|344503_345214_-|phosphate-transport-system-regulatory-protein-PhoU
MDNMNLNKHISGQFNAELESVRNQVLVMGGLVEKQLTDAIAAIHGQDLDAARKIVANDHKVNAMEVAIDEECTRIIAKRQPTASDLRLVMAIIKTITDLERIGDVADKIARMLTDNANKPQPPLVSLENMGRRTIKMLHDVLDAFARMDLDAALAVYKEDDKVDREYESIIRELMTYMMEDPRTIPQVLNVLWAARAIERVGDRCQHICEYIVYYVKGKDVRHTKADDLSDLLGKG
>CP026226.1|AUV15456.1|342942_344262_-|HlyC/CorC-family-transporter
MSFADSLFFLMLLVAGSVFFSLSEISLAASRKIKLQVMADEGNRHAEKVLALQAQPGNFFTVVQIGLNTVAILGGILGESALNPAIRELIAGFYQGPWLGQISSAASFVFVTGMFILIADLMPKRLAMTMPERIAVVVVRPMMLCVTLLMPLVWLFNGMANGLFRLMRISMVRNDEITSDDIYAVMDAGAEAGVIQREEHQLIENVFELQSLGVTSAMTARESLIYFTLQEGEESIKAKIAEHPHNKFLVCDHNLDSIKGFVDAKELLIRVIGGQSIDLNSGSLVQNVIIIPDTLNLYEAMEYFKNHRGDFAVVMNEYALVVGIVTMNDLMSTVMGEWATHVVEEQIVQRDENSWLVDGVTPISDVMRAFDIEEFPENQNYETIAGFIMYMLRKIPKRTDSVKYAGYKFEVVDIDSYKIDQLLVTRVEPASNEKPAQES
>CP026226.1|AUV18979.1|342381_342918_-|hypothetical-protein
MKTHSRALACVALALALGACSQSAPRKPVTPAKPVTPEPAVVVPQQDPDAVVQSAVAEPSPVFDEEYHGPDQGSLESVTALFARGYIESAMRETMLAAVHSDYPLLGMRDVRLTDPVAKFLTSAQARTTAHDYLYAGVQRRLGRPLSPAQWEQIWQGYPHQGRVSDWVKQTKRVLAGR
>CP026226.1|AUV18978.1|340975_342180_+|IS3-family-transposase
MVEVLTGAERRRRRTPQEKIAIVQQTFEPGMTVSHVARLHDVNANQLFKWRKQFQEGSLTAITAGEDVVPASELAAAIKQIRELQRLLGKKTMENEILKEAVEYGRGKKMDCACALVAGGRRLSAVSQALNVSRAQLSVRVHRKPGWQDGRHHRQRDDAALLGRIMEAMAELPSYGYRRVWALLRRQSEATEQPVVNAKRVYRVMREHGLLLERKPAAPLAQQAHKGRVAVKESNRRWCSDGFEFRCDNGEKLRVTFAMDCCDREALDWAASTGGYDSDTVQDVMLRSVERRFGDSLPASPVEWLTDNGSAYRAHETRAFAREIGLEPRTTAVRSPQSNGIAESFVKTMKRDYIEMMPKPDSRTAVGNLAIAFEHYNEHHPHSALGYRSPREFLRSRVSQP
>CP026226.1|AUV15455.1|339846_340749_-|homocysteine-S-methyltransferase-family-protein
MDKQDLWVLDGGMGRELARRGAPFRQPEWSALALMEAPETVREVHQAYATSGARVITTNSYALVPFHIGEARFAAQGEALAALAGQLARDVADEQGGAVKVAGSLPPLFGSYRADLYQAERVSELATPLIRALSPHVDLWLAETMSLIAEPLALKALLPQDSKPFWVSFTLEDEAPGCEPTLRSGERVADAVTALASAGVDAILFNCCQPEVIEGALKVAVAALQVQGRTDVRLGAYANAFPPQPKEATANDGLDEIRGDLGPLDYLGWAERWRRAGANLIGGCCGIGPEHIEALASRLR
>CP026226.1|AUV15454.1|338427_339837_-|amino-acid-permease
MKESKIGLWSLTALVFSSMVGAGIFSLPQNMADVAGARAVLIGWAVTGVGILALAMSFLYLSRLKPELDGGIYSYARAGFGELVGFFSAWGYWLCASIGVVGYLVIAFAALGSFVDTPERVWFGEGNTLAAFIGESCILWAVHLLVARGVQQAALFNLVATLAKSLPLLLFILFACYWFDPVTFAADQEGSTLAVPVSEQVRNTMLITLWVFTGIEGAAVLSARARNKRDVGTATVLGVVLALLLYVLISVLALGILSRPELAALPNPSMAGLMAQMTGSWGKLLISAGLIVSVLASYVSWTLFSAEVPFSAARHGAFPAIFRRENRNGTPIASLWLTSLTVQGCLLLVWLLGKGYTNLLLISTSMILVPYLLIGLFLLKLVFSGKGGQGRGLMRVVALVSSGYGFWLLYAAGVEYLLLSLLLYGPGLLLFLYSRRQLGAEQRLSGRERLLAGVTLLSLIPAVWSFVHV
>CP026226.1|AUV15453.1|337484_338360_+|sterol-desaturase-family-protein
MLTSNWSNRMAHMDVQLLLLYLSPLFLVFIGWEMLYLRKHGTAYPTAGYQWKDLFANATLALMHQGGDALAAIAIAYLYDTLWGWRLFDIELNLWSLLLLFLLQDLCYWLFHFASHHVRWLWASHVVHHSSERLNLSTAFRQSLMYPVSGMWLFWIPMILIGFPPEAVVATVLLSLGFQFFVHTQVVGKLGKLEWIFNTPSHHRVHHASNARYIDRNFAGVLIIWDRLFGTFVEEDLGEPCRFGITKPIHSFNPLTLTFHEWRDMLQEARGLPWRQKLAVLFGKPAGPTSG
>CP026226.1|AUV15452.1|336572_337316_+|amino-acid-ABC-transporter-ATP-binding-protein
MRAATDPIIKATGVEKFYGTEVHALKNVSTQVAEGEVVVIVGPSGSGKSTFLRTLNQLETINDGNIVVDGISLTEPGDVNKLREEVGMVFQSFNLFPHLTVLDNITLAPQKVRGLSRQEAEERAKALLLKVGLSNKAQSYPSQLSGGQQQRVAIARALAMQPRIMLFDEPTSALDPEMVGEVLDVMKGLAREGMTMVVVTHEMGFAREVADRVLFMESGELLVDEKPADFFDNPPSPRLRQFLSQVL
>CP026226.1|AUV15451.1|335511_336483_+|ABC-transporter-permease
MINPKLTRQMEKQPNQLLWHGIFLLLVLAAIFGIYKAVQAVDYTWRWERIPQYIAYQAEQKHYAEFDGTVVADKGQLFLQDDLDPSRRQAIAPKGSQLAEGDTVFLGDTLDVQLSWTAGPIAWGAWVTVKLSLVAGIFAILLGTLAGLARLSPNPALRNLAVTYVELIRGTPLLVQIFIVYFFIGTVLNLDRFTAGVAALAVFTGAYVAEIVRAGISSIHKGQMEAGRSLGMTSAQTMRYVILPQAFKRVLPPLAGQFINLIKDSSLVSVISITDLTKAGREVVSSTFSPFEVWFTVALLYLVLTGTLSFLVRRLEVKYARSN
>CP026226.1|AUV18977.1|334587_335439_+|amino-acid-ABC-transporter-substrate-binding-protein
MPWSRTGAGSRPTTFTTETSFMIKKLILSTLLLCGLANAAPTSTLDAVLERGVLRVGFDAGYQPFEMTNKQGQYIGFDVDLAKMVAKEMGVKVEFVNTAWDGIIPALLTDKFDVIMGGMTVTPQRNLRVNFADPYIVVGQTIVLRKDKAGEIKSFQDLNDPKYKIAVKLGTTGEQAVKRMIPKATLLQFETQDDAKLEVINGKVDAFVYDLPYNAIFASQNQGAVVHLDKPFTFEPLAWAIRKGDQDTLNWFNNYLRQIKGDGSYDRLYKKWFESTAWLNQLK
>CP026226.1|AUV15458.1|345393_346212_-|phosphate-ABC-transporter-ATP-binding-protein
MINVTPSSAPHTATDLLNLTPEQTALEVKDLNLYYGNKQALFNVNMKIPKGQVTAFIGPSGCGKSTLLRCINRMNDLVEICRIEGEIQLHGHNIYDKSVDVSALRRQVGMVFQRPNPFPKSIYENVVYGLRLQGINDRRTLDEAAERSLRGAALWEEVKDRLHDNAFGLSGGQQQRLVIARAIAIEPEVLLLDEPTSALDPISTLTIEELINELKSQFTVVIVTHNMQQAARVSDQTAFMYMGELIEYSNTNTIFTTPAKKKTEDYITGRYG
>CP026226.1|AUV15459.1|346316_347966_-|phosphate-ABC-transporter,-permease-protein-PstA
MGKWFKSGAPWIWMTGGAVSLSLVAVLGLLLLIGWRGLVYFWPHPIYEWQLQDASGNKSVLIGEINDRELVPVERLRAAGQALEGEDREEITRYLVKTGNREFVDLDFRWVLETDIKSRTQPAELAMVERATNGNFYGYITSVKEDGQELTTDLHPALQRVLARANGLSSQANDLQKGAIGSINYQLERLRLKERKAELDDKLTDQLKAELASERQALNDRYQVLEKELFSLRTQADRDSITVKDMRGELVTMPMSRVLDVVWPNDMSLMAKVGHWFHQIGKFVSDDPREANTEGGVFPAIFGTVFMVILMAIIVTPLGVVAAVYLHEYAGKNSLTKIIRIAVINLAGVPSIVYGVFGLGFFVYTLGGSIDRLFYPEALPSPTFGSPGVIWSALTLAILTLPVVIVSTEEGLARIPSTIRQGSLALGATQAETLWRIVLPMASPAIMTGLILAIARAAGEVAPLMLVGVVKLAPTLPMDGNFPYLHVERKFMHLGFHIYDVGFQSPNVEAARPLVYATSFLLVTVIVGLNLTAIGIRNHLREKFRSLEH
>CP026226.1|AUV15460.1|347983_350221_-|phosphate-ABC-transporter-permease
MSSESLNLVMAGSRKRRIKDKLAKYGVTTGGALVLVALLLIFFYLLYVVKPIFNGASMESTASFTLPIKGKTAWLGVEEQNEIGYRFSDLGKVKFFAVQPDGKIKTGQVIGEAQVNGEITAVAPPAPGQKLIAYGFADGKAQVVQPYFKISYPNDVRVIEPSLQYPFGETPVVIDPQGKALTRMVFEATKDKMATAAVTEDGRGVLMVMSGEENFLSGEIEWSNQTYTIPSLPRHVDQMLLTPNLRLLFVREGNRLSVYDIHNLSDISLRNVMEINAPNASVTQVALLSGASSLLVGNDNGVISQWFEVAKDGKRQFTQIRDFKGDAPVVLLTPEHFRKGFISAGSDGTINFFHATGEAKLLGEKIDGGNLAAVAISPRHNLLLTQQGDDFKVFDVENDHPEVTWSALWQQVWYEGYPEPQYVWQSTSASNDFEAKLSLVPLVFGTLKASFYAMVFAVPLGVAGAIYTAYFMSAGLRKYVKPTVEIMAALPTVILGFLAGLWLAPIIEGALPGVILLLILLPMGMLLTALVWNYLPERGRTWLPEGWHAILLIPVLLFIGWGAFALSPIIENAFMHGDSRIWLTHDMGIKFDQRNSLVVGIAMGFAVIPTIFSIAEDAVFSVPKHLTQGSLALGATPWQTLSRVVILTASPGIFSAVMMGLGRAVGETMIVLMATGNTPIMDFSMFQGLRTLAANIAVEMPESEVGSSHYRVLFLAAFVLFVFTFLFNTLAEFVRQRLREKYSSL
>CP026226.1|AUV15461.1|350389_350938_-|tRNA-adenosine(34)-deaminase-TadA
MKPSEVAAQISQREEDERWMRHAMALAARAEGIGEIPVGAVLVLGDKIVAEGWNRSISEHDACAHAEVMALREAGKQLENYRLLDTTLYVTLEPCCMCAGALIHSRVKRVVYGARDLKTGAAGSVFDILLDPRHNHQVALTGEVLADACSAQLSDFFKRRRAEKKAARLAAKEALPHDDTGA
>CP026226.1|AUV15462.1|351434_351659_-|hypothetical-protein
MDACLIDCKPVGDSITLVSTSLFLWPAEKLRILAALYESFKWFCIKFMLIKSGDPMNGGGERKKRQASGVQAKK
>CP026226.1|AUV15463.1|352490_354098_+|malate-synthase-A
MSAPAQTISSTRLRIQGEMLPDYAQILTPDAVALVSELVERFAPQRNELLKQRVARQARIDGGELPDFLPETAHIRDGDWTIRGIPADLQDRRVEITGPVERKMVINALNANVKVFMADFEDSLAPAWNKVIEGQINLRDAVNGTIAYQSPEGKAYTLNPNPAVLICRVRGLHLPEKHVTFDGAPIPGGLFDFALYFLHNHKALLAKGSGPYFYVPKLQSHLEGRWWSEVFAWTEDKFGLPRGTIKATVLIETLPAVFEMDELLYQMKDHIVALNCGRWDYIFSYIKTLKNHSDRVLPDRQVVTMDKPFLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDAAVNEQVFAKVHADKQREADNGHDGTWVAHPGLADTAMAVFNATIPAGAQNQIGVLREQDAPITAADLLAPCEGDRTEAGMRTNIRVALQYLEAWINGNGCVPIYGLMEDAATAEISRTSIWQWIRHGKTLSNGQAVTKALFRQMLAEEQEVVRGEVGEARWQSGRFAEASALMDEITCADTLIDFLTLPGYERL
>CP026226.1|AUV15464.1|354167_355481_+|isocitrate-lyase
MALTREQQIQAIEKDWAENPRWKGIKRGYSAEDVVNLRGSLQPAHTLAQRGADKLWELIHGGAKKGYVNCLGALTGGQAVQQAKAGIEAIYLSGWQVAADNNLSSTMYPDQSLYPANSVPSVVERINNSFARADQIQWANKVGPEDKGFIDYFLPIVADAEAGFGGVLNAFELMKGMIEAGAAGVHFEDQLASVKKCGHMGGKVLVPTQEAVQKLVAARLAADVCGTTTLVIARTDANAADLLTTDADPYDAGFLTGERTSEGFYKVQAGIEQAISRGLAYAPYADMVWCETAKPDLDEARKFAEAIKAQYPDKILAYNCSPSFNWKKNLDDATIARFQQELSDMGYKYQFITLAGIHNMWFHMYELAYQYARGEGMKHYVEMVQQPEFAAAERGYTFVAHQQEVGTGYFDKVTTVIQGGQSSVTALTGSTEEDQFH
>CP026226.1|AUV15465.1|355906_356650_-|DnaA-inactivator-Hda
MIHLPANITVKAQRVKQPAQLSLAVQLPDDETFVSFYPGNNAHLITALKNAAIGQGSPFLYFWGAKGSGRSHLLHATCAEVNARDAAAAYLSLDQFEQLDPSMLDALESLPLVCLDSLEAIAGNALWERALFDFYNRWKEKGEGTLIVTGCSAPRKLGLQLPDLASRLDWGVSFHLDELDDEGKLSALQLRAELRGFKLPIDVGRFLLNRLSRDMRTLLATLNRLDNASFRAKRKLTIPFVKEILEL
>CP026226.1|AUV15466.1|356710_357739_-|DUF2066-domain-containing-protein
MLKRLATLLCCCLPLVVSAAQVTDLYQGKAPTSGDMTAAQSQALGYVLVKVTGKRDILTQPDVVKALAAPADYVQQYSYQDIGSVKFLKADFNVAKVNALVGQSKFALLGPVRPQVAIWLVVDEGERRILPDQSGDGWSEALRAQTQAMGLPVSLPLMDLDDNMAVNATDVWGRFADPVLKASQRYGAEMVVLGKLSPEGEAWSIDWGLYGTKPGAQAGELTELTKGSGSGTQAEVAKGFADALAGWLVQQYGTRLSGVASSQTLVVEGLSDIDGMIQIQKLLQGMASVTKVAIGKLEGDKVTFNLSLQGDKAELVRGLQLESRLHQVEDNESGLRYQWSQP
>CP026226.1|AUV15467.1|357880_358507_-|uracil-phosphoribosyltransferase
MKVVEVKHPLVKHKIGLMREGDISTKRFRELAKEVGSLLTYEATSDFETEKVTIDGWNGPVEVDQIKGKKVTVVPILRAGLGMMDGVLEHMPSARVSVVGIYRDEETLQPVPYFEKIVSNIEERLALVIDPMLATGGSMIATIDLLKKKGCQSIKVLVLVAAPEGIKALEAAHPDVELFCASIDQGLNEKGYIVPGLGDAGDKIFGTK

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Crispr_ID: CP026226_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026226_2

1385250-1385397

Orphan

Consensus_repeat	Method
GACAGGGGAAAACGACGATCAGTTACCATTCTCTGCCCTCTGGCCACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026226_2

>merge|CP026226|2|1385250-1385397|CRISPRCasFinder
GACAGGGGAAAACGACGATCAGTTACCATTCTCTGCCCTCTGGCCACCAGCACCGATCAGGAACTGGCGGCGTCGAATAGTGCCGTCATCCTCCGTGATAGACAGGGGAAAACGACGATCAGTTACCATTCTCTGCCCTCTGACCACC

>CP026226|2|2|1385250-1385397|CRISPRCasFinder
GACAGGGGAAAACGACGATCAGTTACCATTCTCTGCCCTCTGGCCACC	AGCACCGATCAGGAACTGGCGGCGTCGAATAGTGCCGTCATCCTCCGTGATA
GACAGGGGAAAACGACGATCAGTTACCATTCTCTGCCCTCTGACCACC

Protein	Signature genes	Signature genes Name	Protein_function
CP026226.1\|AUV16309.1\|1395109_1396735_+\|phosphoenolpyruvate-carboxykinase-(ATP)	unknown	unknown	gnl\|CDD\|236471
CP026226.1\|AUV16292.1\|1376472_1377141_+\|GMP/IMP-nucleotidase	unknown	unknown	gnl\|CDD\|237882
CP026226.1\|AUV16308.1\|1394072_1394960_+\|Hsp33-family-molecular-chaperone-HslO	unknown	unknown	gnl\|CDD\|234643
CP026226.1\|AUV16301.1\|1386053_1386398_-\|type-II-secretion-system-protein-GspI	unknown	unknown	gnl\|CDD\|376798
CP026226.1\|AUV16306.1\|1390431_1392486_-\|type-II-secretion-system-protein-GspD	unknown	unknown	gnl\|CDD\|274175
CP026226.1\|AUV19047.1\|1392507_1393434_-\|type-II-secretion-system-protein-GspC	unknown	unknown	gnl\|CDD\|273770
CP026226.1\|AUV16297.1\|1382367_1382859_-\|type-II-secretion-system-protein-M	unknown	unknown	gnl\|CDD\|377391
CP026226.1\|AUV16303.1\|1387083_1387515_-\|type-II-secretion-system-protein-GspG	unknown	unknown	gnl\|CDD\|130771
CP026226.1\|AUV16302.1\|1386472_1387036_-\|type-II-secretion-system-protein-GspH	unknown	unknown	gnl\|CDD\|130769
CP026226.1\|AUV16305.1\|1388926_1390432_-\|type-II-secretion-system-protein-GspE	unknown	unknown	gnl\|CDD\|131585
CP026226.1\|AUV16294.1\|1378443_1379349_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
CP026226.1\|AUV16304.1\|1387704_1388925_-\|type-II-secretion-system-protein-GspF	unknown	unknown	gnl\|CDD\|273980
CP026226.1\|AUV16307.1\|1393572_1393971_+\|heat-shock-protein	unknown	unknown	gnl\|CDD\|182397
CP026226.1\|AUV16299.1\|1384152_1385178_-\|type-II-secretion-protein-K	unknown	unknown	gnl\|CDD\|377165
CP026226.1\|AUV19045.1\|1375716_1376277_-\|ADP-compounds-hydrolase-NudE	unknown	unknown	gnl\|CDD\|183303
CP026226.1\|AUV19046.1\|1379343_1380609_-\|tyrosine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235645
CP026226.1\|AUV16295.1\|1380754_1381564_+\|LuxR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197715
CP026226.1\|AUV16293.1\|1377220_1378327_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|239201
CP026226.1\|AUV16298.1\|1382855_1384040_-\|type-II-secretion-system-protein-GspL	unknown	unknown	gnl\|CDD\|273768
CP026226.1\|AUV16296.1\|1381612_1382371_-\|type-II-secretion-protein-N	unknown	unknown	gnl\|CDD\|376490

Protein	Function_ID	Function_description	E-value
CP026226.1\|AUV16309.1\|1395109_1396735_+\|phosphoenolpyruvate-carboxykinase-(ATP)	gnl\|CDD\|236471	PRK09344, PRK09344, phosphoenolpyruvate carboxykinase.	0
CP026226.1\|AUV16292.1\|1376472_1377141_+\|GMP/IMP-nucleotidase	gnl\|CDD\|237882	PRK14988, PRK14988, GMP/IMP nucleotidase; Provisional.	1.7315e-94
CP026226.1\|AUV16308.1\|1394072_1394960_+\|Hsp33-family-molecular-chaperone-HslO	gnl\|CDD\|234643	PRK00114, hslO, Hsp33 family molecular chaperone HslO.	1.88069e-135
CP026226.1\|AUV16301.1\|1386053_1386398_-\|type-II-secretion-system-protein-GspI	gnl\|CDD\|376798	pfam02501, T2SSI, Type II secretion system (T2SS), protein I. The Type II secretion system, also called Secretion-dependent pathway (SDP), is responsible for the transport of proteins across the outer membrane first exported to the periplasm by the Sec or Tat translocon in Gram-negative (diderm) bacteria. As members of the T2SJ family, members of the T2SI family are pseudopilins containing prepilin signal sequences.	8.9401e-29
CP026226.1\|AUV16306.1\|1390431_1392486_-\|type-II-secretion-system-protein-GspD	gnl\|CDD\|274175	TIGR02517, Putative_type_II_secretion_system_protein_D, type II secretion system protein D. In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking].	0
CP026226.1\|AUV19047.1\|1392507_1393434_-\|type-II-secretion-system-protein-GspC	gnl\|CDD\|273770	TIGR01713, Type_II_secretion_system_protein_C, type II secretion system protein C. This model represents GspC, protein C of the main terminal branch of the general secretion pathway, also called type II secretion. This system transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking].	5.25001e-66
CP026226.1\|AUV16297.1\|1382367_1382859_-\|type-II-secretion-system-protein-M	gnl\|CDD\|377391	pfam04612, T2SSM, Type II secretion system (T2SS), protein M. This family of membrane proteins consists of Type II secretion system protein M sequences from several Gram-negative (diderm) bacteria. The precise function of these proteins is unknown, though in Vibrio cholerae, the T2SM (EpsM) protein interacts with the T2SL (EpsL) protein, and also forms homodimers.	1.8417e-47
CP026226.1\|AUV16303.1\|1387083_1387515_-\|type-II-secretion-system-protein-GspG	gnl\|CDD\|130771	TIGR01710, Type_II_secretion_system_protein_G, type II secretion system protein G. This model represents GspG, protein G of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	1.80096e-63
CP026226.1\|AUV16302.1\|1386472_1387036_-\|type-II-secretion-system-protein-GspH	gnl\|CDD\|130769	TIGR01708, Type_II_secretion_system_protein_H, type II secretion system protein H. This model represents GspH, protein H of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	4.76858e-38
CP026226.1\|AUV16305.1\|1388926_1390432_-\|type-II-secretion-system-protein-GspE	gnl\|CDD\|131585	TIGR02533, Type_II_secretion_system_protein_E, type II secretion system protein E. This family describes GspE, the E protein of the type II secretion system, also called the main terminal branch of the general secretion pathway. This model separates GspE from the PilB protein of type IV pilin biosynthesis. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
CP026226.1\|AUV16294.1\|1378443_1379349_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.41286e-52
CP026226.1\|AUV16304.1\|1387704_1388925_-\|type-II-secretion-system-protein-GspF	gnl\|CDD\|273980	TIGR02120, Putative_general_secretion_pathway_protein_F, type II secretion system protein F. This membrane protein is a component of the terminal branch complex of the general secretion pathway (GSP), also known as the"Type II" secretion pathway. The GSP transports proteins (generally virulence-associated cell wall hydrolases) across the outer membrase of the bacterial cell. Transport across the inner membrane is often, but not exclusively handled by the Sec system. This model was constructed from the broader subfamily model, pfam00482 which includes components of pilin complexes (PilC) as well as other related genes. GspF is nearly always gene clustered with other GSP subunits. Some genes from Xylella and Xanthomonas strains score below the trusted cutoff due to excessive divergence from the family such that a sequence from Deinococcus which does not appear to be GspF scores higher. [Protein fate, Protein and peptide secretion and trafficking].	0
CP026226.1\|AUV16307.1\|1393572_1393971_+\|heat-shock-protein	gnl\|CDD\|182397	PRK10348, PRK10348, ribosome-associated heat shock protein Hsp15; Provisional.	3.96597e-43
CP026226.1\|AUV16299.1\|1384152_1385178_-\|type-II-secretion-protein-K	gnl\|CDD\|377165	pfam03934, T2SSK, Type II secretion system (T2SS), protein K. Members of this family are involved in the Type II protein secretion system. The T2SK family includes proteins such as ExeK, PulK, OutX and XcpX.	6.19337e-99
CP026226.1\|AUV19045.1\|1375716_1376277_-\|ADP-compounds-hydrolase-NudE	gnl\|CDD\|183303	PRK11762, nudE, adenosine nucleotide hydrolase NudE; Provisional.	2.60908e-122
CP026226.1\|AUV19046.1\|1379343_1380609_-\|tyrosine--tRNA-ligase	gnl\|CDD\|235645	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated.	0
CP026226.1\|AUV16295.1\|1380754_1381564_+\|LuxR-family-transcriptional-regulator	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	4.85124e-17
CP026226.1\|AUV16293.1\|1377220_1378327_-\|oxidoreductase	gnl\|CDD\|239201	cd02803, OYE_like_FMN_family, Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	1.18822e-97
CP026226.1\|AUV16298.1\|1382855_1384040_-\|type-II-secretion-system-protein-GspL	gnl\|CDD\|273768	TIGR01709, Type_II_secretion_system_protein_L, type II secretion system protein L. This model represents GspL, protein L of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking].	6.68592e-85
CP026226.1\|AUV16296.1\|1381612_1382371_-\|type-II-secretion-protein-N	gnl\|CDD\|376490	pfam01203, T2SSN, Type II secretion system (T2SS), protein N. Members of the T2SN family are involved in the Type II protein secretion system. The precise function of these proteins is unknown.	2.54658e-53

>CP026226.1|AUV16299.1|1384152_1385178_-|type-II-secretion-protein-K
MAIKRGRGRSRTTLGRQGGMALLVVLLILAVMVIVASNMSGRLQLELRRTANLTLGKQAWWYAMSAEALVIKVLNQDFKDDPDRVSLGQNWAREDGVFPVEDGTLSGRVRDLQSCFNLNSLSVPLKEGENGDDLEAQPYQFKVFRALLAQLEVDDYEAVQLTDAIRDWTDKDTQLVSSNGAEDAYYEGLNPPYLVANQRMLGTDELRAVRGVSASLYARLAPYVCTLPNDKLVVNINTIRPEQAALLVGLYQGKIGLDDAKRVLTSRPKKGWKNKQEMTEQLQVQPGAITGLDGALDIKSSFFEARLLAEVGETRARLETVFQRGKDNKLVMLRRLSGGAE
>CP026226.1|AUV16298.1|1382855_1384040_-|type-II-secretion-system-protein-GspL
MSESLVIRLGTNAQQPVHWLVWSAQEQEIIASGILASAHALGELQERAGGRPVVTLVPGSDLIFRRVNLPGKYSRQSAAALPYLLEEQIASDVDDLHLVVLGHQGREVDLMAVDKGKMHSWLGWLEQAGLKTLHLLPDVLALPLAADGWSALQLGEEWLVRQGPRQGIVAEESLLAMLLAAQTEPVTLHCHTPIPAMAAGNWQGADPELPMLLLAKGALTCQANLLQGPYRPQTEYARYWLQWRKVAVLAGVLLLVALVQRGVHLHQLAEQDKALKAEIRQVYTRIFPGETRIVNVRSQMTQHLQQLGQAPQDGVLLLLTELAPVFAEVPGLKPEVLRFDAARGELRLQVTAPGFTEIERFRELAGKRFEVQQGEVRSTEGKVEGALVLKGRSS
>CP026226.1|AUV16297.1|1382367_1382859_-|type-II-secretion-system-protein-M
MMDKLQSWWRGISAREQRLVAVGGSVLLIGLFYWAIWQPVANRIAERERQVVNQQQTLAWLKEKGQEVLAMQGGQGRQIDTGGTLDGVVNRTAFNQKIKIARLQPQGQELQVWIDTVPFDDLLIWLATLSDQYGVQVQIIELAREGLAPGLVKVRRLQLSRSQ
>CP026226.1|AUV16296.1|1381612_1382371_-|type-II-secretion-protein-N
MKRKIVIASLFLLAYLGFLLAQLPASLVVRHLPLPPNLVRLEGVSGTLWSGQAARVQYASESLTQLRWDLDGWSLLRLAPEVSVRFGERSGLNGQGILGWNGAAFGRDITLNAPAPWVLERVPMRPPFPLTAAGQLQLKIDQFAQGSPWCDNLYGDLHWYDAQADTPAGKLALGDPEITLTCLDSRLVAEIKQGSEAVQVLGKLELQANRQYLFQGTLKPGPELPDQMKQGLPFLGQPDGQGRFPLRYQGRI
>CP026226.1|AUV16295.1|1380754_1381564_+|LuxR-family-transcriptional-regulator
MPPSPATDTLSLTAAVDALHGSGFPAALVRLIQQQVAFDCALLLGVGQRPVYLYDNLHHQRALLFDRYLTRHFSQDPFMQALEQGLGAGVWTLAQVSRGRLDPEYRHHFYQATGWQEEVGLILPVRGGLTLMLFLGRLDKRSSLSRDELVRLEALFPLVHSLCRQHWREETPRLARSPARSDGTDLKGAVEQAIASVGGDQLTRRERQVAGLLLQGLDTEAIAGALGIGSGTVKNHRKHLYAKLNLHSRAELFSFFLNHLITAPAGAPP
>CP026226.1|AUV19046.1|1379343_1380609_-|tyrosine--tRNA-ligase
MTNPHLLDELTQRGLVAQNSDPVALADHLATPRTVYCGFDPTAGSLHIGHLVPLLMLRRFQLAGHTPVALVGGATGLIGDPSFKASERTLNSAETVQGWVASLSAQISALLPASDGLEAPLLVNNADWMGQMSALDFLRDIGKHFSVNAMLARESVRQRLARPDQGISFTEFSYALLQSQDFAVLNQRLGCTLQIGGNDQWGNITSGMDLTRRLHQAQVYGMTLPLITKADGTKFGKTEGGAIWLDPALTSPYAFYQFWLGTADEDVYRFLRYYSFMPLAEIETLEAEDAKRQGRKLAQQVLADELTELVHGKGALAAAQRISESLFSGEVARLGESDLAQLAQDGMPSSPIKGETDLVTLLVECGLANSKRIARELLAAGAVSVNGAIRRDEPLTADDRLFGRYLLLRRGKKQYHLVIRS
>CP026226.1|AUV16294.1|1378443_1379349_+|LysR-family-transcriptional-regulator
MSHHKLDTLYLMRLLVAIVRCGSFAAAAAQLGITPSKASKDLRHLEQSLGSVLLSRTTRRVQLTDAGELAYRQADQMIALHEQLLDGLQRRRSALCGELRITAPDLWGEVVLTPVLLRFRADHPEVRIIADFSNTPADLLRDNLHVAFRSTELGTQPYLARPIAVDDLVLCASADYLDRHPPLTTPQDLHQHSLITRSQEYGRHERWPLLAQGREIPLEVAGELAFSSKKAVHQGMRQGLGIARLPRYLVAAELAEGVVREVLPDYRPKGAYFYALYTQRRAESALVGHFLDYVIEALTPS
>CP026226.1|AUV16293.1|1377220_1378327_-|oxidoreductase
MNKTLGDSFHFERAGLRLKNRAVLAPLTHNMSGAGGDPGQAELDWLARCARGGFGLLIAAATQVQPGGRCWAGQPALMTDAQQQAFTALADSARQAGALAVVQLHHGGMRALPELNDGAPVGPCALAPGGRYPLGVKGLSEAEILTLIDAFVSAAERAHGAGLHGIELHAAHHFLLCNFLNPLHNLRTDRWGGSLANRARILVEIVRGIRARLPRGFLVGVRLSPESYAHIQGIELAHQLAVARLLADEGIDYLHFSMGDSFKAVAGDPDGGALLEAVRVGLAGRVPLMVAGKISDADSAERALAGGADLVAVGTAALGNPDWMERVSRGLPLHAAPFTAAHLTEVGFTPSALDYLASMGVLAPRDAA
>CP026226.1|AUV16292.1|1376472_1377141_+|GMP/IMP-nucleotidase
MSTPLPWHQIDTVLLDMDGTLIDLHFDSHLWQTLVPARYAERLGLPLAEAKAQIDTHYHAVNGTLDWYCVDYWTRTLGLDIRALKQEILEKIQWRPNVIPFLAALKAAGKQVVLFTNAHPASLSVKDARLGLAQHLDLMVSTHELGWSKESQHCWQALAERLAFDPARTLFVDDSERILAASAEFGIAHQLGIRHPDSQMPPLTFQHFPALDDYADLLPLGA
>CP026226.1|AUV19045.1|1375716_1376277_-|ADP-compounds-hydrolase-NudE
MAHDKSKPEILKAEIVAESRLFKVESLHLKFSNGEERVYERMRGGNRGAVMVVPLFDAHTLLLVREYAAGTHSYELGFPKGLIDPGENAFEAGNRELMEEAGFGASSLTLLKQVSLAPGYFSSRMDILLARDLYPEQRVGDEPEPLEVIPWPLNRIDELLARPDFTESRSISALLLASKWLAEQGN
>CP026226.1|AUV16301.1|1386053_1386398_-|type-II-secretion-system-protein-GspI
MTLLEVMVALAVFAIAGLAVMKTASEHLAGLNYLEQKTLATWVVENQLVQQKLEGKWPGDSWVEGDEEMAGQTWYWRYRGVATADSNFRALDMEVRTAPKADSPVAMIRTYLSR
>CP026226.1|AUV16302.1|1386472_1387036_-|type-II-secretion-system-protein-GspH
MKVASWARHQAGFTLLEVLLVAMLMGLVATAVTLSMGGARGDRELDKQARRFMATLQQAQEYSVMDGRLLGLRVEENGWQFMSRDPKDRKWRALTGDRLLGPVTLPEGMTLAVELEGFNWRTASDERQEQGRDERERTPQILVFPGGELSPFVLTLSQQDEDLHYLRTVRGDEFGRLSLLQDEEEEE
>CP026226.1|AUV16303.1|1387083_1387515_-|type-II-secretion-system-protein-GspG
MQKRRQSGFTLLEVMVVIVILGILASLVVPNLMGNKEKADQQKAVSDIVALENALDMYKLDNNRYPTTEQGLDALVNKPTASPEPRSYREGGYIKRLPQDPWGNQYQLLSPGQFGKIDIFSMGMDGEAGTDDDIGNWNLKDFQ
>CP026226.1|AUV16304.1|1387704_1388925_-|type-II-secretion-system-protein-GspF
MAAFEYKALDGKGRNKSGVLEGDSARQVRQLLREQGLTPLEVNETTEKAKREANRFVLFRRGASTSELALITRQLATLVGAGLTIEEALKAVAEQCEKAHLRSLVATVRSKVVEGYSLADSLGAFPHVFDQLFRSMVAAGEKSGHLEKVLNRLADYTEQRQHMRTKLLQAMIYPIVLTLVAVGVISILLTAVVPKVVAQFEHMGQQLPGTTRFLIGTSELLQHYGLWFLLLLGIGGLIWRWWLTDDKRRRRWHQVILRLPVIGRVSRGLNTARFARTLSILNASAVPLLEGMKIAGEVLSNDYARMRIGEATERVREGTSLRKSLDETRIFPPMMLHMIASGEQSGELDSMLERAADNQDREFETQVNIALGVFEPMLVVSMAGVVLFIVMSILQPILELNNMVNL
>CP026226.1|AUV16305.1|1388926_1390432_-|type-II-secretion-system-protein-GspE
MAAYQLDGSELPAPLPELPFAFARNFGAILTERQGAPVLLCRQGISPQTLLEVRRVAGCAFAVEQLGNDEFETLLMAHYQRDSSEARQLMEDLGNEMDFFALAEELPQSEDLLDADDDAPIIRLINAMLSEAIKEEASDIHIETFERALVIRFRIDGVLREILRPHRKLASLLVSRIKVMSRMDIAEKRVPQDGRISLRIGGRAVDVRVSTMPSSYGERVVLRLLDKNNVRLELKQLGMTLANRNIISELIRKPHGIILVTGPTGSGKSTTLYAALSEINSRDRNILTVEDPIEYDLEGVGQTQVNSKVDMTFARGLRAILRQDPDVVMVGEIRDLETAQIAVQASLTGHLVMSTLHTNTAIGAITRMRDMGIEPFLLSSSLLAVLAQRLVRTLCPDCRAPHPVTEQERVAMGIELAPDQQIWRPVGCEQCNHTGYRGRTGIHELVVVDEAVREAIHSASGELAIERLIRGHTPSIRRDGIDKVLKGQTSLEEVLRVTRED
>CP026226.1|AUV16306.1|1390431_1392486_-|type-II-secretion-system-protein-GspD
MTNKGKGWRLATMAAALMMAGSAWATEYSASFKNADIEEFINTVGKNLNKTIIIEPSVRGKINVRSYDLLNEDQYYQFFLSVLDVYGFAVVPMNNGVLKVVRSKDAKTSAIPVVDDTNPGVGDEMVTRVVPVRNVSVRELAPLLRQLNDNAGGGNVVHYEPSNVLLITGRAAVVNRLVEVVRRVDKAGDQDMDVIKLKFASAGEMVRLVTNLNKDGSNQGANASLLLSPKVVADERTNSVVISGEPKARARIIQMVRQLDRDLQSQGNTRVFYLKYGKAKDLVDVLKGVSSSIAADKKGGAAATATGGASIGGGQLAISADETTNALVITAQPDVMAELEQVIAKLDIRRAQVLVEAIIVEISDGDGMNLGVQWANTNGGGTQFTDTGLPIGSLAIAAKDYKDNGNTDGLSSLAGSFSGMAAGFYHGDWAALVTALSTNSKNDILSTPSIVTMDNKEASFNVGQEVPVQSGSQSSTTSDQVFNTIERKTVGTKLVVTPQINEGDSVLLNIEQEVSSVAQKQATGTANLGPTFDTRTVKNAVLVKSGETVVLGGLMDEQTQEQISKVPLLGDIPVLGYLFRSSKTSTAKRNLMVFIRPTILRDANVYSGVSSNKYTLFRAEQLSRAAEEGYATSPARQVLPAYGQDVMMSPEVQQQIQRMQAQQQATATGVRAQVQEQPFVQSKP
>CP026226.1|AUV19047.1|1392507_1393434_-|type-II-secretion-system-protein-GspC
MPYTIANRLGCQTILRKMTLPFRDDLLTSLLARCKAMPLSRFSQPLFWLLLLLLAQQCAVLTWRLYELAQPAPLTPWQPSVTSVQGSGGDRLDLGNLSRLSLFGKALQPQADKAAETVAADAPKTQLNAQLNGVLASSDPAKSIAIIAHNGTQNSYGIGDYIDGTQARIRQVFADRVIIARDGRDETLMLDGEEYGKPLPKPARQEGLSSVRSELLGNPGKITDYLNISPVRVDGRMTGYRLNPGRNPELFNQLGLVANDLAVSINGLDLRDNAQAMQAMQQVAGATEMTVTVERQGQLYDVYVGLSE
>CP026226.1|AUV16307.1|1393572_1393971_+|heat-shock-protein
MSNPAQSSTQVRLDKWLWAARFYKTRSLARDQIDGGKVHYNGQRTKPGKAVEVGALVRFWQGQDEREVRVLEVSEQRKSAPLAQQLYEETEASLKKRAENSEARRFNSQFAPSPERRPDKQERRQLIRVKQS
>CP026226.1|AUV16308.1|1394072_1394960_+|Hsp33-family-molecular-chaperone-HslO
MMSNQDLLYRYLFEEYEVRGELVQLDRTYRHIIDAQNYPVQVQHLLGELLVATSLLTATLKFEGSITVQLQGDGPVRLAVINGDNNQQLRGVARYEGELPTDGKLQSLIGNGHLVITITPDQGERYQGIIALEADTLAACLEHYFAQSEQLATRLWIRTGHHEGEPRAAGILLQELPAQSEDHSEDFDHLVQLTTTIKDEELFGLDAEEILYRLYHQDKVRVFDPQAIEFRCTCSRARCEGALLQIDKEEAVSMVQELGKIDMHCDYCGAHYEFDGIDIETLFSRAPGNDANQLH
>CP026226.1|AUV16309.1|1395109_1396735_+|phosphoenolpyruvate-carboxykinase-(ATP)
MTIVVEPTLAQQLKLDQYGIKNSQEIVRNPSYEQLFAEETRSDLEGFERGVVTELGAVNVNTGIFTGRSPKDKYIVKDATTQDTVWWSDQGKNDNKAITPEVWSHLKGLVTKQLSGKRLFVVDGFCGANPDTRLAVRIITEVAWQAHFVKNMFIRPSEEELKTFKPDFVVMNGAKCTNPNWKEQGLNSENFVAFNMTEKMQLIGGTWYGGEMKKGMFSMMNYFLPLRGIASMHCSANVGKDGDVAIFFGLSGTGKTTLSTDPKRQLIGDDEHGWDDHGVFNFEGGCYAKTIKLSEEAEPDIYHAIRRDALLENVTVAADGTIDFDDGSRTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVAKLTKEQTKYHFLSGFTAKLAGTERGITEPTPTFSSCFGAAFLSLHPTKYGQELVKRMEAAGAEAYLVNTGWNGTGKRISIKDTRGIIDAILDGSIEKAPTKVLPVFNLEVPTELPGVNPAILDPRDTYADQAEWDAKAADLAGRFIKNFERFTDNDEGKRLVAAGPQL

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Crispr_ID: CP026226_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026226_3

1387630-1387731

Orphan

Consensus_repeat	Method
CCTCACAGATTCACCATATTGTTGAGCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026226_3

>merge|CP026226|3|1387630-1387731|CRISPRCasFinder
CCTCACAGATTCACCATATTGTTGAGCTCGAGCGAGTTGACCGCGGGATCGACCGATGTCACACGCACGCCAGCCTCACAGATTCACCATGTTGTTGAGCTC

>CP026226|3|3|1387630-1387731|CRISPRCasFinder
CCTCACAGATTCACCATATTGTTGAGCTC	GAGCGAGTTGACCGCGGGATCGACCGATGTCACACGCACGCCAG
CCTCACAGATTCACCATGTTGTTGAGCTC

Protein	Signature genes	Signature genes Name	Protein_function
CP026226.1\|AUV16312.1\|1399547_1400000_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP026226.1\|AUV16313.1\|1400131_1400602_+\|glycine-zipper-2TM-domain-containing-protein	unknown	unknown	gnl\|CDD\|225675
CP026226.1\|AUV16309.1\|1395109_1396735_+\|phosphoenolpyruvate-carboxykinase-(ATP)	unknown	unknown	gnl\|CDD\|236471
CP026226.1\|AUV16308.1\|1394072_1394960_+\|Hsp33-family-molecular-chaperone-HslO	unknown	unknown	gnl\|CDD\|234643
CP026226.1\|AUV16301.1\|1386053_1386398_-\|type-II-secretion-system-protein-GspI	unknown	unknown	gnl\|CDD\|376798
CP026226.1\|AUV16311.1\|1397607_1399410_+\|X-Pro-aminopeptidase	unknown	unknown	gnl\|CDD\|238518
CP026226.1\|AUV19047.1\|1392507_1393434_-\|type-II-secretion-system-protein-GspC	unknown	unknown	gnl\|CDD\|273770
CP026226.1\|AUV16297.1\|1382367_1382859_-\|type-II-secretion-system-protein-M	unknown	unknown	gnl\|CDD\|377391
CP026226.1\|AUV16303.1\|1387083_1387515_-\|type-II-secretion-system-protein-GspG	unknown	unknown	gnl\|CDD\|130771
CP026226.1\|AUV16306.1\|1390431_1392486_-\|type-II-secretion-system-protein-GspD	unknown	unknown	gnl\|CDD\|274175
CP026226.1\|AUV16298.1\|1382855_1384040_-\|type-II-secretion-system-protein-GspL	unknown	unknown	gnl\|CDD\|273768
CP026226.1\|AUV16310.1\|1396908_1397574_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
CP026226.1\|AUV16307.1\|1393572_1393971_+\|heat-shock-protein	unknown	unknown	gnl\|CDD\|182397
CP026226.1\|AUV16300.1\|1385367_1386009_-\|type-II-secretion-system-protein-GspJ	unknown	unknown	gnl\|CDD\|130772
CP026226.1\|AUV16299.1\|1384152_1385178_-\|type-II-secretion-protein-K	unknown	unknown	gnl\|CDD\|377165
CP026226.1\|AUV19046.1\|1379343_1380609_-\|tyrosine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235645
CP026226.1\|AUV16295.1\|1380754_1381564_+\|LuxR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197715
CP026226.1\|AUV16305.1\|1388926_1390432_-\|type-II-secretion-system-protein-GspE	unknown	unknown	gnl\|CDD\|131585
CP026226.1\|AUV16302.1\|1386472_1387036_-\|type-II-secretion-system-protein-GspH	unknown	unknown	gnl\|CDD\|130769
CP026226.1\|AUV16296.1\|1381612_1382371_-\|type-II-secretion-protein-N	unknown	unknown	gnl\|CDD\|376490

Protein	Function_ID	Function_description	E-value
CP026226.1\|AUV16312.1\|1399547_1400000_+\|N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.8093e-14
CP026226.1\|AUV16313.1\|1400131_1400602_+\|glycine-zipper-2TM-domain-containing-protein	gnl\|CDD\|225675	COG3133, SlyB, Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane].	3.0401e-48
CP026226.1\|AUV16309.1\|1395109_1396735_+\|phosphoenolpyruvate-carboxykinase-(ATP)	gnl\|CDD\|236471	PRK09344, PRK09344, phosphoenolpyruvate carboxykinase.	0
CP026226.1\|AUV16308.1\|1394072_1394960_+\|Hsp33-family-molecular-chaperone-HslO	gnl\|CDD\|234643	PRK00114, hslO, Hsp33 family molecular chaperone HslO.	1.88069e-135
CP026226.1\|AUV16301.1\|1386053_1386398_-\|type-II-secretion-system-protein-GspI	gnl\|CDD\|376798	pfam02501, T2SSI, Type II secretion system (T2SS), protein I. The Type II secretion system, also called Secretion-dependent pathway (SDP), is responsible for the transport of proteins across the outer membrane first exported to the periplasm by the Sec or Tat translocon in Gram-negative (diderm) bacteria. As members of the T2SJ family, members of the T2SI family are pseudopilins containing prepilin signal sequences.	8.9401e-29
CP026226.1\|AUV16311.1\|1397607_1399410_+\|X-Pro-aminopeptidase	gnl\|CDD\|238518	cd01085, APP, X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	4.60457e-124
CP026226.1\|AUV19047.1\|1392507_1393434_-\|type-II-secretion-system-protein-GspC	gnl\|CDD\|273770	TIGR01713, Type_II_secretion_system_protein_C, type II secretion system protein C. This model represents GspC, protein C of the main terminal branch of the general secretion pathway, also called type II secretion. This system transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking].	5.25001e-66
CP026226.1\|AUV16297.1\|1382367_1382859_-\|type-II-secretion-system-protein-M	gnl\|CDD\|377391	pfam04612, T2SSM, Type II secretion system (T2SS), protein M. This family of membrane proteins consists of Type II secretion system protein M sequences from several Gram-negative (diderm) bacteria. The precise function of these proteins is unknown, though in Vibrio cholerae, the T2SM (EpsM) protein interacts with the T2SL (EpsL) protein, and also forms homodimers.	1.8417e-47
CP026226.1\|AUV16303.1\|1387083_1387515_-\|type-II-secretion-system-protein-GspG	gnl\|CDD\|130771	TIGR01710, Type_II_secretion_system_protein_G, type II secretion system protein G. This model represents GspG, protein G of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	1.80096e-63
CP026226.1\|AUV16306.1\|1390431_1392486_-\|type-II-secretion-system-protein-GspD	gnl\|CDD\|274175	TIGR02517, Putative_type_II_secretion_system_protein_D, type II secretion system protein D. In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking].	0
CP026226.1\|AUV16298.1\|1382855_1384040_-\|type-II-secretion-system-protein-GspL	gnl\|CDD\|273768	TIGR01709, Type_II_secretion_system_protein_L, type II secretion system protein L. This model represents GspL, protein L of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking].	6.68592e-85
CP026226.1\|AUV16310.1\|1396908_1397574_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.86922e-44
CP026226.1\|AUV16307.1\|1393572_1393971_+\|heat-shock-protein	gnl\|CDD\|182397	PRK10348, PRK10348, ribosome-associated heat shock protein Hsp15; Provisional.	3.96597e-43
CP026226.1\|AUV16300.1\|1385367_1386009_-\|type-II-secretion-system-protein-GspJ	gnl\|CDD\|130772	TIGR01711, Type_II_secretion_system_protein_J, type II secretion system protein J. This model represents GspJ, one of two proteins highly conserved at their N-termini and described by pfam02501 but easily separable phylogenetically. The other is GspI. Both GspI and GspJ are proteins of the type II secretion pathway, or main terminal branch of the general secretion pathway. This pathway carries proteins across the outer membrane. Note that proteins of type II secretion are cryptic in E. coli K-12 - present but not yet demonstrated to act on any target.	3.03784e-107
CP026226.1\|AUV16299.1\|1384152_1385178_-\|type-II-secretion-protein-K	gnl\|CDD\|377165	pfam03934, T2SSK, Type II secretion system (T2SS), protein K. Members of this family are involved in the Type II protein secretion system. The T2SK family includes proteins such as ExeK, PulK, OutX and XcpX.	6.19337e-99
CP026226.1\|AUV19046.1\|1379343_1380609_-\|tyrosine--tRNA-ligase	gnl\|CDD\|235645	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated.	0
CP026226.1\|AUV16295.1\|1380754_1381564_+\|LuxR-family-transcriptional-regulator	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	4.85124e-17
CP026226.1\|AUV16305.1\|1388926_1390432_-\|type-II-secretion-system-protein-GspE	gnl\|CDD\|131585	TIGR02533, Type_II_secretion_system_protein_E, type II secretion system protein E. This family describes GspE, the E protein of the type II secretion system, also called the main terminal branch of the general secretion pathway. This model separates GspE from the PilB protein of type IV pilin biosynthesis. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
CP026226.1\|AUV16302.1\|1386472_1387036_-\|type-II-secretion-system-protein-GspH	gnl\|CDD\|130769	TIGR01708, Type_II_secretion_system_protein_H, type II secretion system protein H. This model represents GspH, protein H of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	4.76858e-38
CP026226.1\|AUV16296.1\|1381612_1382371_-\|type-II-secretion-protein-N	gnl\|CDD\|376490	pfam01203, T2SSN, Type II secretion system (T2SS), protein N. Members of the T2SN family are involved in the Type II protein secretion system. The precise function of these proteins is unknown.	2.54658e-53

>CP026226.1|AUV16303.1|1387083_1387515_-|type-II-secretion-system-protein-GspG
MQKRRQSGFTLLEVMVVIVILGILASLVVPNLMGNKEKADQQKAVSDIVALENALDMYKLDNNRYPTTEQGLDALVNKPTASPEPRSYREGGYIKRLPQDPWGNQYQLLSPGQFGKIDIFSMGMDGEAGTDDDIGNWNLKDFQ
>CP026226.1|AUV16302.1|1386472_1387036_-|type-II-secretion-system-protein-GspH
MKVASWARHQAGFTLLEVLLVAMLMGLVATAVTLSMGGARGDRELDKQARRFMATLQQAQEYSVMDGRLLGLRVEENGWQFMSRDPKDRKWRALTGDRLLGPVTLPEGMTLAVELEGFNWRTASDERQEQGRDERERTPQILVFPGGELSPFVLTLSQQDEDLHYLRTVRGDEFGRLSLLQDEEEEE
>CP026226.1|AUV16301.1|1386053_1386398_-|type-II-secretion-system-protein-GspI
MTLLEVMVALAVFAIAGLAVMKTASEHLAGLNYLEQKTLATWVVENQLVQQKLEGKWPGDSWVEGDEEMAGQTWYWRYRGVATADSNFRALDMEVRTAPKADSPVAMIRTYLSR
>CP026226.1|AUV16300.1|1385367_1386009_-|type-II-secretion-system-protein-GspJ
MIQSNTRPSHHRGFTLLEMLVAIAIFATLSLGAYQVLQGVLTSDEVAKRKEARLSELQLAFSLLERDITQMVPRSGRIDGENNKVLLAASRFGQQSDDWGMAFIRGGWLNPDGILPRSGLQRVGWRLKGQTLERLSYLYPDPAIGTEPRIQPVLTGVTALRLYFYDKGQWKEEWTQRDLLPYGLAVELELEDYGTIRRQFLIGAGGQRAENGN
>CP026226.1|AUV16299.1|1384152_1385178_-|type-II-secretion-protein-K
MAIKRGRGRSRTTLGRQGGMALLVVLLILAVMVIVASNMSGRLQLELRRTANLTLGKQAWWYAMSAEALVIKVLNQDFKDDPDRVSLGQNWAREDGVFPVEDGTLSGRVRDLQSCFNLNSLSVPLKEGENGDDLEAQPYQFKVFRALLAQLEVDDYEAVQLTDAIRDWTDKDTQLVSSNGAEDAYYEGLNPPYLVANQRMLGTDELRAVRGVSASLYARLAPYVCTLPNDKLVVNINTIRPEQAALLVGLYQGKIGLDDAKRVLTSRPKKGWKNKQEMTEQLQVQPGAITGLDGALDIKSSFFEARLLAEVGETRARLETVFQRGKDNKLVMLRRLSGGAE
>CP026226.1|AUV16298.1|1382855_1384040_-|type-II-secretion-system-protein-GspL
MSESLVIRLGTNAQQPVHWLVWSAQEQEIIASGILASAHALGELQERAGGRPVVTLVPGSDLIFRRVNLPGKYSRQSAAALPYLLEEQIASDVDDLHLVVLGHQGREVDLMAVDKGKMHSWLGWLEQAGLKTLHLLPDVLALPLAADGWSALQLGEEWLVRQGPRQGIVAEESLLAMLLAAQTEPVTLHCHTPIPAMAAGNWQGADPELPMLLLAKGALTCQANLLQGPYRPQTEYARYWLQWRKVAVLAGVLLLVALVQRGVHLHQLAEQDKALKAEIRQVYTRIFPGETRIVNVRSQMTQHLQQLGQAPQDGVLLLLTELAPVFAEVPGLKPEVLRFDAARGELRLQVTAPGFTEIERFRELAGKRFEVQQGEVRSTEGKVEGALVLKGRSS
>CP026226.1|AUV16297.1|1382367_1382859_-|type-II-secretion-system-protein-M
MMDKLQSWWRGISAREQRLVAVGGSVLLIGLFYWAIWQPVANRIAERERQVVNQQQTLAWLKEKGQEVLAMQGGQGRQIDTGGTLDGVVNRTAFNQKIKIARLQPQGQELQVWIDTVPFDDLLIWLATLSDQYGVQVQIIELAREGLAPGLVKVRRLQLSRSQ
>CP026226.1|AUV16296.1|1381612_1382371_-|type-II-secretion-protein-N
MKRKIVIASLFLLAYLGFLLAQLPASLVVRHLPLPPNLVRLEGVSGTLWSGQAARVQYASESLTQLRWDLDGWSLLRLAPEVSVRFGERSGLNGQGILGWNGAAFGRDITLNAPAPWVLERVPMRPPFPLTAAGQLQLKIDQFAQGSPWCDNLYGDLHWYDAQADTPAGKLALGDPEITLTCLDSRLVAEIKQGSEAVQVLGKLELQANRQYLFQGTLKPGPELPDQMKQGLPFLGQPDGQGRFPLRYQGRI
>CP026226.1|AUV16295.1|1380754_1381564_+|LuxR-family-transcriptional-regulator
MPPSPATDTLSLTAAVDALHGSGFPAALVRLIQQQVAFDCALLLGVGQRPVYLYDNLHHQRALLFDRYLTRHFSQDPFMQALEQGLGAGVWTLAQVSRGRLDPEYRHHFYQATGWQEEVGLILPVRGGLTLMLFLGRLDKRSSLSRDELVRLEALFPLVHSLCRQHWREETPRLARSPARSDGTDLKGAVEQAIASVGGDQLTRRERQVAGLLLQGLDTEAIAGALGIGSGTVKNHRKHLYAKLNLHSRAELFSFFLNHLITAPAGAPP
>CP026226.1|AUV19046.1|1379343_1380609_-|tyrosine--tRNA-ligase
MTNPHLLDELTQRGLVAQNSDPVALADHLATPRTVYCGFDPTAGSLHIGHLVPLLMLRRFQLAGHTPVALVGGATGLIGDPSFKASERTLNSAETVQGWVASLSAQISALLPASDGLEAPLLVNNADWMGQMSALDFLRDIGKHFSVNAMLARESVRQRLARPDQGISFTEFSYALLQSQDFAVLNQRLGCTLQIGGNDQWGNITSGMDLTRRLHQAQVYGMTLPLITKADGTKFGKTEGGAIWLDPALTSPYAFYQFWLGTADEDVYRFLRYYSFMPLAEIETLEAEDAKRQGRKLAQQVLADELTELVHGKGALAAAQRISESLFSGEVARLGESDLAQLAQDGMPSSPIKGETDLVTLLVECGLANSKRIARELLAAGAVSVNGAIRRDEPLTADDRLFGRYLLLRRGKKQYHLVIRS
>CP026226.1|AUV16305.1|1388926_1390432_-|type-II-secretion-system-protein-GspE
MAAYQLDGSELPAPLPELPFAFARNFGAILTERQGAPVLLCRQGISPQTLLEVRRVAGCAFAVEQLGNDEFETLLMAHYQRDSSEARQLMEDLGNEMDFFALAEELPQSEDLLDADDDAPIIRLINAMLSEAIKEEASDIHIETFERALVIRFRIDGVLREILRPHRKLASLLVSRIKVMSRMDIAEKRVPQDGRISLRIGGRAVDVRVSTMPSSYGERVVLRLLDKNNVRLELKQLGMTLANRNIISELIRKPHGIILVTGPTGSGKSTTLYAALSEINSRDRNILTVEDPIEYDLEGVGQTQVNSKVDMTFARGLRAILRQDPDVVMVGEIRDLETAQIAVQASLTGHLVMSTLHTNTAIGAITRMRDMGIEPFLLSSSLLAVLAQRLVRTLCPDCRAPHPVTEQERVAMGIELAPDQQIWRPVGCEQCNHTGYRGRTGIHELVVVDEAVREAIHSASGELAIERLIRGHTPSIRRDGIDKVLKGQTSLEEVLRVTRED
>CP026226.1|AUV16306.1|1390431_1392486_-|type-II-secretion-system-protein-GspD
MTNKGKGWRLATMAAALMMAGSAWATEYSASFKNADIEEFINTVGKNLNKTIIIEPSVRGKINVRSYDLLNEDQYYQFFLSVLDVYGFAVVPMNNGVLKVVRSKDAKTSAIPVVDDTNPGVGDEMVTRVVPVRNVSVRELAPLLRQLNDNAGGGNVVHYEPSNVLLITGRAAVVNRLVEVVRRVDKAGDQDMDVIKLKFASAGEMVRLVTNLNKDGSNQGANASLLLSPKVVADERTNSVVISGEPKARARIIQMVRQLDRDLQSQGNTRVFYLKYGKAKDLVDVLKGVSSSIAADKKGGAAATATGGASIGGGQLAISADETTNALVITAQPDVMAELEQVIAKLDIRRAQVLVEAIIVEISDGDGMNLGVQWANTNGGGTQFTDTGLPIGSLAIAAKDYKDNGNTDGLSSLAGSFSGMAAGFYHGDWAALVTALSTNSKNDILSTPSIVTMDNKEASFNVGQEVPVQSGSQSSTTSDQVFNTIERKTVGTKLVVTPQINEGDSVLLNIEQEVSSVAQKQATGTANLGPTFDTRTVKNAVLVKSGETVVLGGLMDEQTQEQISKVPLLGDIPVLGYLFRSSKTSTAKRNLMVFIRPTILRDANVYSGVSSNKYTLFRAEQLSRAAEEGYATSPARQVLPAYGQDVMMSPEVQQQIQRMQAQQQATATGVRAQVQEQPFVQSKP
>CP026226.1|AUV19047.1|1392507_1393434_-|type-II-secretion-system-protein-GspC
MPYTIANRLGCQTILRKMTLPFRDDLLTSLLARCKAMPLSRFSQPLFWLLLLLLAQQCAVLTWRLYELAQPAPLTPWQPSVTSVQGSGGDRLDLGNLSRLSLFGKALQPQADKAAETVAADAPKTQLNAQLNGVLASSDPAKSIAIIAHNGTQNSYGIGDYIDGTQARIRQVFADRVIIARDGRDETLMLDGEEYGKPLPKPARQEGLSSVRSELLGNPGKITDYLNISPVRVDGRMTGYRLNPGRNPELFNQLGLVANDLAVSINGLDLRDNAQAMQAMQQVAGATEMTVTVERQGQLYDVYVGLSE
>CP026226.1|AUV16307.1|1393572_1393971_+|heat-shock-protein
MSNPAQSSTQVRLDKWLWAARFYKTRSLARDQIDGGKVHYNGQRTKPGKAVEVGALVRFWQGQDEREVRVLEVSEQRKSAPLAQQLYEETEASLKKRAENSEARRFNSQFAPSPERRPDKQERRQLIRVKQS
>CP026226.1|AUV16308.1|1394072_1394960_+|Hsp33-family-molecular-chaperone-HslO
MMSNQDLLYRYLFEEYEVRGELVQLDRTYRHIIDAQNYPVQVQHLLGELLVATSLLTATLKFEGSITVQLQGDGPVRLAVINGDNNQQLRGVARYEGELPTDGKLQSLIGNGHLVITITPDQGERYQGIIALEADTLAACLEHYFAQSEQLATRLWIRTGHHEGEPRAAGILLQELPAQSEDHSEDFDHLVQLTTTIKDEELFGLDAEEILYRLYHQDKVRVFDPQAIEFRCTCSRARCEGALLQIDKEEAVSMVQELGKIDMHCDYCGAHYEFDGIDIETLFSRAPGNDANQLH
>CP026226.1|AUV16309.1|1395109_1396735_+|phosphoenolpyruvate-carboxykinase-(ATP)
MTIVVEPTLAQQLKLDQYGIKNSQEIVRNPSYEQLFAEETRSDLEGFERGVVTELGAVNVNTGIFTGRSPKDKYIVKDATTQDTVWWSDQGKNDNKAITPEVWSHLKGLVTKQLSGKRLFVVDGFCGANPDTRLAVRIITEVAWQAHFVKNMFIRPSEEELKTFKPDFVVMNGAKCTNPNWKEQGLNSENFVAFNMTEKMQLIGGTWYGGEMKKGMFSMMNYFLPLRGIASMHCSANVGKDGDVAIFFGLSGTGKTTLSTDPKRQLIGDDEHGWDDHGVFNFEGGCYAKTIKLSEEAEPDIYHAIRRDALLENVTVAADGTIDFDDGSRTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVAKLTKEQTKYHFLSGFTAKLAGTERGITEPTPTFSSCFGAAFLSLHPTKYGQELVKRMEAAGAEAYLVNTGWNGTGKRISIKDTRGIIDAILDGSIEKAPTKVLPVFNLEVPTELPGVNPAILDPRDTYADQAEWDAKAADLAGRFIKNFERFTDNDEGKRLVAAGPQL
>CP026226.1|AUV16310.1|1396908_1397574_+|GntR-family-transcriptional-regulator
MTPPYKTRTQMVMENLRGRILRGEFAAGAPLRQDAIAKELAVSRIPVREALMQLEAQGLVKFEAHRGAVVTMLDASAIEELFYLRALLEADTLFHAVDLMTEETFAQAQAILAQFDLALESGTQIEHWAELNHRFHATLYQAANRPQALELIAQINLSCDRYVRFELLFAQGGVDKAEREHARLLELCRARRKHEAVVLLKQHIEAAGQSIRQILASGHHQ
>CP026226.1|AUV16311.1|1397607_1399410_+|X-Pro-aminopeptidase
MNHFEIIETRVAQVRATLATLELDAFIVPHDDEHLGEYIPAYAERLDWITGFNGSAGLAIIMAHRAALFIDGRYTVQARMQAPAELFEFLHLNEDPHVQWLAEQLPSGSRVGFDARLHSLAWYQNAKAVLTERGIELVRIDENPIDLHWSDRPAPTKSPVILYSEELAGQSSQAKREMLASDLRKRGLDAVLLTQAEPINWLLNLRGRDVERLPVVLGFAVLYANTTMDFFVDTDKIDCFAFSQHVGQDVSVYPIDKLGDVLQRIGEDQQKVLADPNTANAWTQLVMEEAGAILVAGQDPTMLPKACKNPVELAGMRAAHLRDGVAVTRFLAWLDRLIASGEFDGVDEGTLADQLEAFRHEQEHYVEPSFDTISALGPNAAMCHYRHTNGTPRAFGQDSIYLVDSGAQYLDGTTDITRTVKVGEVTDEHRAMFTRVLQGHIALDQARFPRGTAGIQLDVLARMPLWQAGYNYDHGTGHGVGHFLSVHEGPQRIAPKGSLVALQPGMVLSNEPGYYREDAFGIRCENLVVVTEQEARGELTMLGFERLTYVPFDIRLIDRSLLSPAEFRWINEYHAEVYRRLSPLLEGEDLAWLEQATSLL
>CP026226.1|AUV16312.1|1399547_1400000_+|N-acetyltransferase
MHSSPVLRLATHTDMHAIWQIDADVFGEDVYPGFFFRQAMDLWPELLVVAEREGRLLGYALGGLGQDRSQGWLLSLAVRPEARGFGLAEQMILQVEQGLLKLEVERVRLTVDPANPAQRLYFRLGYQQLAEERGYFGPGEDRLLLEKALT
>CP026226.1|AUV16313.1|1400131_1400602_+|glycine-zipper-2TM-domain-containing-protein
MFKRIALVTLLAATTAITGCANSDVYSGDVYTKDRAKQVQTVSYGTILSTRPVKIQADENSLIGTIGGAVVGGLLGSTIGGGRGSDIAAAGGAIAGAAAGKAAGDKLNQVDGVELEIKKENGESIVVVQKASPTFVPGARVRMTQGNGTINVAVVN

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Crispr_ID: CP026226_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026226_4

1720183-1720277

Orphan

Consensus_repeat	Method
CTGTTCCTGATGTTTGAACACGGATAAGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026226_4

>merge|CP026226|4|1720183-1720277|CRISPRCasFinder
CTGTTCCTGATGTTTGAACACGGATAAGGCTGCCAGCACTCACCCCAGTGCTGTTCGTGGTTTATCTGTTCCGGATGTTTGAACACGGATAAGGC

>CP026226|4|4|1720183-1720277|CRISPRCasFinder
CTGTTCCTGATGTTTGAACACGGATAAGGC	TGCCAGCACTCACCCCAGTGCTGTTCGTGGTTTAT
CTGTTCCGGATGTTTGAACACGGATAAGGC

Protein	Signature genes	Signature genes Name	Protein_function
CP026226.1\|AUV16590.1\|1721936_1723640_-\|urocanate-hydratase	unknown	unknown	gnl\|CDD\|235448
CP026226.1\|AUV16594.1\|1726723_1727383_-\|carbonate-dehydratase	unknown	unknown	gnl\|CDD\|238448
CP026226.1\|AUV16580.1\|1705786_1707499_-\|type-II/IV-secretion-system-protein	unknown	unknown	gnl\|CDD\|225363
CP026226.1\|AUV16587.1\|1714987_1716907_-\|RNase-E-specificity-factor-CsrD	unknown	unknown	gnl\|CDD\|236833
CP026226.1\|AUV16582.1\|1709747_1711424_-\|pilus-(MSHA-type)-biogenesis-protein-MshL	unknown	unknown	gnl\|CDD\|274176
CP026226.1\|AUV16595.1\|1727510_1728365_-\|RNA-polymerase-sigma-factor-RpoH	unknown	unknown	gnl\|CDD\|235838
CP026226.1\|AUV19066.1\|1711494_1711797_-\|MSHA-biogenesis-protein-MshK	unknown	unknown	unknown
CP026226.1\|AUV16591.1\|1723685_1724624_-\|formimidoylglutamase	unknown	unknown	gnl\|CDD\|237500
CP026226.1\|AUV16592.1\|1724616_1725921_-\|imidazolonepropionase	unknown	unknown	gnl\|CDD\|236478
CP026226.1\|AUV16581.1\|1707573_1708710_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274350
CP026226.1\|AUV16583.1\|1711852_1712500_-\|MSHA-biogenesis-protein-MshJ	unknown	unknown	gnl\|CDD\|377391
CP026226.1\|AUV19067.1\|1717424_1718960_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
CP026226.1\|AUV16596.1\|1728817_1729771_-\|cell-division-protein-FtsX	unknown	unknown	gnl\|CDD\|182910
CP026226.1\|AUV16597.1\|1729770_1730439_-\|cell-division-ATP-binding-protein-FtsE	unknown	unknown	gnl\|CDD\|225438
CP026226.1\|AUV16585.1\|1713092_1713956_-\|MSHA-biogenesis-protein-MshI	unknown	unknown	unknown
CP026226.1\|AUV16584.1\|1712499_1713093_-\|MSHA-biogenesis-protein-MshI	unknown	unknown	gnl\|CDD\|377469
CP026226.1\|AUV16593.1\|1726008_1726713_-\|histidine-utilization-repressor	unknown	unknown	gnl\|CDD\|188194
CP026226.1\|AUV16598.1\|1730661_1732404_-\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
CP026226.1\|AUV16586.1\|1714025_1714991_+\|1-aminocyclopropane-1-carboxylate-deaminase	unknown	unknown	gnl\|CDD\|225313
CP026226.1\|AUV16589.1\|1720402_1721935_-\|histidine-ammonia-lyase	unknown	unknown	gnl\|CDD\|236484

Protein	Function_ID	Function_description	E-value
CP026226.1\|AUV16590.1\|1721936_1723640_-\|urocanate-hydratase	gnl\|CDD\|235448	PRK05414, PRK05414, urocanate hydratase; Provisional.	0
CP026226.1\|AUV16594.1\|1726723_1727383_-\|carbonate-dehydratase	gnl\|CDD\|238448	cd00883, beta_CA_cladeA, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.	1.48009e-121
CP026226.1\|AUV16580.1\|1705786_1707499_-\|type-II/IV-secretion-system-protein	gnl\|CDD\|225363	COG2804, PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion].	0
CP026226.1\|AUV16587.1\|1714987_1716907_-\|RNase-E-specificity-factor-CsrD	gnl\|CDD\|236833	PRK11059, PRK11059, regulatory protein CsrD; Provisional.	0
CP026226.1\|AUV16582.1\|1709747_1711424_-\|pilus-(MSHA-type)-biogenesis-protein-MshL	gnl\|CDD\|274176	TIGR02519, related_to_type_II_protein_secretion_protein, pilus (MSHA type) biogenesis protein MshL. Members of this family are predicted secretins, that is, outer membrane pore proteins associated with delivery of proteins from periplasm to the outside of the cell. Related families include GspD of type II secretion (TIGR02517), the YscC/HrcC family from type III secretion (TIGR02516), and the PilQ secretin of type IV pilus formation (TIGR02515). Members of this family are found in gene clusters associated with MSHA (mannose-sensitive hemagglutinin) and related pili, and appear to be the secretin of this pilus system. [Cell envelope, Surface structures].	1.80524e-86
CP026226.1\|AUV16595.1\|1727510_1728365_-\|RNA-polymerase-sigma-factor-RpoH	gnl\|CDD\|235838	PRK06596, PRK06596, RNA polymerase factor sigma-32; Reviewed.	0
CP026226.1\|AUV16589.1\|1720402_1721935_-\|histidine-ammonia-lyase	gnl\|CDD\|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0
CP026226.1\|AUV16591.1\|1723685_1724624_-\|formimidoylglutamase	gnl\|CDD\|237500	PRK13776, PRK13776, formimidoylglutamase; Provisional.	0
CP026226.1\|AUV16592.1\|1724616_1725921_-\|imidazolonepropionase	gnl\|CDD\|236478	PRK09356, PRK09356, imidazolonepropionase; Validated.	0
CP026226.1\|AUV16581.1\|1707573_1708710_-\|hypothetical-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	9.32906e-10
CP026226.1\|AUV16583.1\|1711852_1712500_-\|MSHA-biogenesis-protein-MshJ	gnl\|CDD\|377391	pfam04612, T2SSM, Type II secretion system (T2SS), protein M. This family of membrane proteins consists of Type II secretion system protein M sequences from several Gram-negative (diderm) bacteria. The precise function of these proteins is unknown, though in Vibrio cholerae, the T2SM (EpsM) protein interacts with the T2SL (EpsL) protein, and also forms homodimers.	0.000126015
CP026226.1\|AUV19067.1\|1717424_1718960_+\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.84959e-82
CP026226.1\|AUV16596.1\|1728817_1729771_-\|cell-division-protein-FtsX	gnl\|CDD\|182910	PRK11026, ftsX, cell division ABC transporter subunit FtsX; Provisional.	2.90595e-77
CP026226.1\|AUV16584.1\|1712499_1713093_-\|MSHA-biogenesis-protein-MshI	gnl\|CDD\|377469	pfam05137, PilN, Fimbrial assembly protein (PilN).	0.000879713
CP026226.1\|AUV16593.1\|1726008_1726713_-\|histidine-utilization-repressor	gnl\|CDD\|188194	TIGR02018, Histidine_utilization_repressor, histidine utilization repressor, proteobacterial. This model represents a proteobacterial histidine utilization repressor. It is usually found clustered with the enzymes HutUHIG so that it can regulate its own expression as well. A number of species have several paralogs and may fine-tune the regulation according to levels of degradation intermediates such as urocanate. This family belongs to the larger GntR family of transcriptional regulators. [Energy metabolism, Amino acids and amines, Regulatory functions, DNA interactions].	6.36068e-96
CP026226.1\|AUV16598.1\|1730661_1732404_-\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	0
CP026226.1\|AUV16586.1\|1714025_1714991_+\|1-aminocyclopropane-1-carboxylate-deaminase	gnl\|CDD\|225313	COG2515, Acd, 1-aminocyclopropane-1-carboxylate deaminase [Amino acid transport and metabolism].	3.91492e-54
CP026226.1\|AUV16597.1\|1729770_1730439_-\|cell-division-ATP-binding-protein-FtsE	gnl\|CDD\|225438	COG2884, FtsE, Predicted ATPase involved in cell division [Cell division and chromosome partitioning].	3.18206e-123

>CP026226.1|AUV19067.1|1717424_1718960_+|EAL-domain-containing-protein
MSARSPLWIPLALFCVPPLLMLLLTPLLSDKLAHHLLQTKERALLDYQQERNLLLDHDVPAQLAHFAFDCGPTDMALLRSPQYYNRHIRLAGLQLANGSGCSTLGPALPQLADAGMPVSPDFHLSSTAPMFDTERETLVYARRNGNLAYWVLDSSWSHELLRTPCNDCFYLEFNHKHPAQFGLFFPRGNKHIREEANPMRLLSFDPQHQVEQTLWAGEALKRYARSQIHRDGLWSAGALGALLAALYWSLRNYRRSLKGLLQRGLARREFIPFYQPIVDSRNRRVVGFEALLRWQRGRDLVSPGTFIAYAEEQGLILPMTDQLLERILADLPVLAPHQWVSVNLVAGHIEQPRLRTQLQRHGWPSPARLTFELTERDPIKHIQGAMAEIAALQERGYHFKLDDFGTGYGGFAYLQRLGIRQIKIDKMFVDTIGTDDLKRSVLDATIAFGLKSGMEMIAEGVETQEQVDYLHRHGVHLIQGYVYAKPMPLSKLKIWLMAWQEGETTSPSDPH
>CP026226.1|AUV16587.1|1714987_1716907_-|RNase-E-specificity-factor-CsrD
MKLTTQLVSFITLCVISAMAMVMLGGVFSFRQMGMELQQNRVDSLVEIIDKQLGVTDDQQALARWLPSLLRASHVVELEIRQDKQRVYWFRDVQQQTDESLLIAYSEAIPNQAGMRADFKLDRPFKEFEYSMKAMFGISLGIFIVVFGLWYSIRWLRQQLRGAELLAERAQLILDGKLTKLAHDPAEEWPVSASQALTHLLTELADARKERSRFDNFIRSNAFVDKTTGIGNRLFFDNRLESAIMEASVISGGVLLIELAGLEELDPELSGRPSQELLMEASATIAAFVRKHSGALQARYAGQVFAVLLPNMSESEMVDGASQLLKSLQRLHWPEAVNADTAVYLGAVCYQAQDSLLKVQEEAELALKSARLQGHSGWFLFEKSLNEEASSKGTVRWRTLISRRIEEQGIDFYVQPVQQERDQVVLQQELLIRLHDEQGRELQAGVFMPMAEKAGLLLPLDRLVVARALRLLRQRPASSCPISLSLCAQNLLTREFQRELFFELFQLPRSTNEGLILQLSESQVTRHYEALKRPLRAMRMLGCRLAIDHAGQDVVSTQYIKEFEIHFLKLHPSLVREIHLRQVNQMAVRSLVGGCANTQARVIAVGVESGDEWKMLRHLGVHAGQGPWFADPEPLNLPD
>CP026226.1|AUV16586.1|1714025_1714991_+|1-aminocyclopropane-1-carboxylate-deaminase
MTNDASTATLAPTGDDPMAPLQLPSPLHRIRHPLLAAHDVTLWCKRDDLIHPTLSGNKWRKLKYHLQQAQMLGKGHILSFGGAYSNHIHALAAAGLRLGVRTTGIIRGEGDTVSNPTLKAAKGWGMDLVFVDRQDYRRRQDPEWLARFEDDDTLLVPEGGSSPLAIPGVAELVDEVPFSPDLWVLPCASGGTLAGLIAGKRAQEQILAIAVLKGADFITGEVCRLHPAAATTPGWRIALDHHDGGYARFSPALWQWVQAFSAETGLPLEPIYSGKAMWGLFRELAAGRIARGSKIIFIHTGGLQGLAGLEEQGRLSPRPGR
>CP026226.1|AUV16585.1|1713092_1713956_-|MSHA-biogenesis-protein-MshI
MKSLFRRSPSSHQVGILLASDRILLACVDPVPVFASQPVNGPHDWSKALAELFSRYGLAKSKVRVALAASLYQQIQIDKPAVPDAEMAGALPWAIKDFVNEPVLQLAMDYVDLPTPPAGRPRINVVCMPKSRVQQVADAVNGAATLEAIVSDELAMTALYEADQMVRMLLWQPRGQELQLLVFHRGGLCFSRQLRGFASLTGSHEPDADQLDALALEIQRSIDYLAGHLKLPEPGQLQLAIASSAMGVLVRHLEQTFGFPVSAMANKAVLAGVEYLSAYGAALGRSD
>CP026226.1|AUV16584.1|1712499_1713093_-|MSHA-biogenesis-protein-MshI
MKHHINLYGAEFRPRRLWASLPQMALVWGGVLVLLLGATLFYGWQQQGLDRELAGVRAQLDVQRGEARRLDAELARHLANADLQRQLADKREELGAKQALMQQLGHLSLQKSQGYAGVMADLARLRDPRLSLQRIEISDGRINLAGVAERSQDVPAWVNRFRQTPSLAGKQFGELTLSRDKEGQLAFQLSGIARETP
>CP026226.1|AUV16583.1|1711852_1712500_-|MSHA-biogenesis-protein-MshJ
MDMKAQWQGWAQQIAALSLRERILILLTGVVLLGAMGIYGWLDDADTRLGQDRQALAAAQRDLEILTLENQGKQARLGRDPDAQVREQLASVETTLRQMDAELLAQTVDLIPAHEMPAVLEALLSRSANLHMLALTSLKPEPLMAGEQKVNLFRHGIRLQLEGGYFDVYQYLKALEALPRHFYWKGFDYRVVEHPKAAVAMEIYTLSTSKEFIRG
>CP026226.1|AUV19066.1|1711494_1711797_-|MSHA-biogenesis-protein-MshK
MALWGSLLALQAQAEVLQDPTLPLAGSGSAASVAKEAGLPRLQSVILGSGPALAVLDGQSYRVGQQVNGFRLVGISADSVVLEKAGKRQTLTLFGSKIRM
>CP026226.1|AUV16582.1|1709747_1711424_-|pilus-(MSHA-type)-biogenesis-protein-MshL
MKKHPFCLLPLALAVAGCTTYRHPEPVQAKDALKQAMSEQSPTAPLTSLPPSVQSELLQLNRPQQPMTIPEKRMRIAAHDVDAVEFFGSLFKGSRYSVAVHPGVAGVISVELKDVTLQEALATVGDMYGFDVQRKGNVFHVYPAGLRTETIPVNYLMMARRGLSRTSVSTGGVTANDNNNGNNNNFDNGLNNSGNNNSQGNTASGDNNTNSNGTRIETDSNNDYWTDLRDSLQTLIGTGEGRAVITSPQAGLVTVRAYPKELKAVREFLDQSGEHLKRQVVLEARILEVSLNEGYEQGVDWSGLSASWDGGKGITGGGSLMDSPIASTPNQIFRALGGGAGFTISDGNFNVAVSLLKTQGDVNTLSSPRVTATNNQKAVIKVGTDEYFVTNASTTTTTSGTSAPIVTPNVELTPFFSGIALDVTPQIDEQGKVLLHIHPSVIDTEEQSKTINVGTADPLVLPLAKSSIRESDTVVQANNGDIIVIGGLMKTDRQEIVSKVPLLGDIPWVGEAFTNRRESNRKVELVILLKPTVVEKDTWQKELQRSSELLDKWYPPKG
>CP026226.1|AUV16581.1|1707573_1708710_-|hypothetical-protein
MSVINQMLKDLDRRQQEAEGAAVYVAPVRQQGWWMLVLTLLCTLALGILGWRTWIFWQQSQRASLPAAQVEAPRTAPAVAPSAPLAVVATTQAVSSAAPMAKVPTASAESTAARVAPSAAEQAPADEAVLADEGNPQEALGDETIPSDEELQPDLYAELAAEQGAEEAPAPAAPRKPGILKIETVELSDAELATLAERKATTAMAKGRMQEAQDGYYEVLAHDPHNQGAREQLAGLLYGAGRLTEAAQVLEEGLRLDPAQADLRLLLARVAISGGDRQKALDWLTGYQPDIASNLDYYATWAGLAQELGQPVQASEMYVRLLRQQPDQGRWWLGLGVAEDGQGHRQRALDAYRNAQLHGNLGEASTQWLEQRIGQLTH
>CP026226.1|AUV16580.1|1705786_1707499_-|type-II/IV-secretion-system-protein
MAQPRLKMRLGDLLVQEQIISDDQLQLALQQQRQTGRKLGTTLIDLGFISEVQLLTFLARQLDVPFFDLNNLTIDVSAVTLLPEVQARRYRALAVNLSDDKVTVVMSDPADLSALDAIAALLSPRELVLAVAREGQLLEYFDRLYRRTREIENFAVQLHEEHQETGFELGAGSLNAATDEGEATVAKLLRSLFEDAVQVGASDIHIEPDEKVLRIRQRIDGVLHENILSEVRIAQALVLRLKLVAGLDISEKRLPQDGRFNMKVRGRDVDVRMSTMPVQYGESVVMRLLDQSSGILSLAETGMPPAILTRFRRQLKRPHGMILVTGPTGSGKTTTLYGALSELNQASHKIITVEDPVEYRLPRISQVQVNPKIGLTFSQVLRSTLRQDPDILLVGEMRDNETVEIGLRGAITGHLVLTTLHTNDAVTSALRLIDMGAPGYLVASALRAVVAQRLVRRVCEHCACETAPDEGQATWLSVLSGEAPGQHRYRKGRGCQSCNFTGYAGRIGVYELLELDQPMMDALRRNDAEGFARAARAHEHYRPLALTALDYAREGITSVDEVLRLAEDLG
>CP026226.1|AUV16589.1|1720402_1721935_-|histidine-ammonia-lyase
MFELNLQPGKLCLATLRRVSREPVHVSLDPAALAGIHASAAVVTKVIEQNRVVYGINTGFGLLANTRIPVEQLDELQRSIVLSHAAGIGEYMDDATVRLMMVLKVNSLARGFSGIRLTVLEALMTLINAEVYPVVPKKGSVGASGDLAPLAHMSCLLIGEGKARHKGELIDAATALKIAGLEPIALAPKEGLALLNGTQASTAFALEGLFHAEDLYAGAITIGAMSVEAALGSRRPFDARIHEVRGQRGQIDAAACYRHLLVDGSEIGMSHHNCEKVQDPYSLRCQPQVMGACLTQIRQAAEVLVCEANAVSDNPLVFAEDEEIISGGNFHAEPVAFAADNLALAIAEIGSLSERRMALLIDSRMSGLPAFLVNNGGVNSGFMIAQVTSAALASENKTLAHPASVDSLPTSANQEDHVSMATFAGRRLADMAENTRGILAVELLAAAQGLDFRAPLRSTELIELAKGRLREEVSFYDKDRYFAPDIEAAAALLGRASYNDLIPAGTLPSL
>CP026226.1|AUV16590.1|1721936_1723640_-|urocanate-hydratase
MSVQHQDPRHDPSRVIRAPHGTQLTAKSWLTEAPLRMLMNNLDPDVAEHPQSLVVYGGIGRAARNWACYDKIVEVLTRLEDDQTLLVQSGKPVGVFQTHKDAPRVLIANSNLVPHWANWEHFNELDKKGLMMYGQMTAGSWIYIGTQGIVQGTYETFFAVANQHFNGEPKGRWILTGGLGGMGGAQPLAATMAGFSMIAVECDETRIDFRLRTRYVDKKAHSLDEALAMIEEAKRSGTAVSVGLLGNAADVFAELVARGITPDVVTDQTSAHDPVHGYLPQGWSVAQWRDLQKSAPDEVNVAARRSMARQVEAMLTLQSRGAATLDYGNNIRQMALEEGVKNAFDFPGFVPAYIRPLFCEGIGPFRWVALSGDPEDIYKTDQKVKELIPDDPHLHNWLDMARERIAFQGLPARICWVGVKDRVRLGLAFNEMVKNGELKAPVVIGRDHLDSGSVASPNRETESMMDGSDAVSDWPLLNALLNTAGGATWVSLHHGGGVGMGFSQHSGVVIVCDGTDDAAKRVGRVLRNDPATGVMRHADAGYEIAINCAHEAKLDLPMIDATGKGVK
>CP026226.1|AUV16591.1|1723685_1724624_-|formimidoylglutamase
MDKFNGIDMSVWQGRQDPEDGELALRWHDRVQPWQGSREPGVVLLGFACDEGVRRNKGRVGAAGAPLAVRKLLANTAWHLGAPVYDGGDLACEDGDLDAAHGRLAERVASALDQGHFPLVLGGGHEVAFGSWSGLNRHLGGEGRVGIINFDAHFDLRMKQEQASSGTPFFQIAEQCAAQGTPFHYACLGVAETANTAALFARAEALGVWHVLDEAMTPTELPALLGGLDAFIARCDHLYLTIDLDVLPAAVMPGVSAPAARGVELAVIEPLIAHIRASGKLRLADLAEYNPNLDQDNRSARVAARLVHQLTK
>CP026226.1|AUV16592.1|1724616_1725921_-|imidazolonepropionase
MNLILSFFSEIGYKSLYIHLEVGMNMELLNCERVWLNVTPATLRPDLADYGLLEPHALGVRDGKIHALVPMQDLKGPYAASWQDMKGKLVTPGLIDCHTHLIFAGSRAEEFELRQKGVPYAEIARKGGGIISTVRATRAASEERLYELALPRIKSLIREGVTTVEIKSGYGLTLEDELKMLRVARRLGETQPIRVKTTLLAAHAVPPEYRDDPDSWVETICQEIIPAAAEAGLADAVDVFCEHIGFSLAQTEQVYLAADQYNLAVKGHMDQLSNLGGSTLAAHFGALSVDHLEYLDQDGILALAHRGVVATLLPTAFYFLKETKLPPIAALRKAGVPMAVSSDINPGTAPIVSLRMAMNMACTLFGLTPVEAMAGVTRHAARALGEQERLGQLKVGMLADFLVWNCGHPAEISYLIGVDQLVSRVVNGEETLHG
>CP026226.1|AUV16593.1|1726008_1726713_-|histidine-utilization-repressor
MAPALYLQIKQHILDGIRERHYQAGDRIPTEAALCEQFAVSRMTVNKALRELVAEGWLVRTAGSGSFVADRRTESPLLAIRNIADEIAERGSEYSARVIRLQRQAADEKVAVRLGLRVGAPTFHSLIVHQADGEPLQLEERFVDAERLPGYGEQDFTQQTPNSYLMEICPLSEMEHVVEAVLPSAGEAGLLQVRVDTPCLLLHRRTWSDGFLVSYARLLSPGSRYKLSSKTRLA
>CP026226.1|AUV16594.1|1726723_1727383_-|carbonate-dehydratase
MKLLNDLFTNNREWAERIKAEDPNFFATLSAQQAPEYLWIGCSDSRVPANQLMGLLPGDVFVHRNVANLVVHTDFNCLSVLQYAVEVLKVKHIIVCGHYGCGGVKAAMQNQELGLIDNWLRNIKDVYFKYGEQLEAIEDEHERFDYLCELNVAEQVANVCHTTIIQNAWRKGQELAVHGWIYGIKDGLLHDLDLCISGPDQIPDVYRAWPDMRPPHRRR
>CP026226.1|AUV16595.1|1727510_1728365_-|RNA-polymerase-sigma-factor-RpoH
MGTSLQRTMALIPQGSLEGYIQAVNSIPVLSAEEERELAMRLQQDGDLEAARQLVMSHLRFVVHVAKSYSGYGLPQADLVQEGNIGLMKAVKRFDPSVGVRLVSFAVHWIKAEIHEYVLRNWRMVKVATTKAQRKLFFNLRKSKKRLGWLNHEEVQAVAADLGVSAADVTEMEARMSNYDQAFDLVGDDEDEGGFAPVHYLEDKSSDLAANIENDNWDSHATRRLSAAMATLDERSQHIIRARWLDDESKTTLQELADTYGVSAERVRQLEKNALKKLKDAMDA
>CP026226.1|AUV16596.1|1728817_1729771_-|cell-division-protein-FtsX
MAIVRHKQPPLRRLMMYGVDHVRQAFASLGELWRNPLASLMTLAVLGVSLALPSCFHVLLKNAEVVEGSWQTSSQISLYLRKDLPEQSILDMKQRILLYPEVESVTYMNRDEALREFREISGFGDALDYLDSNPLPPVLSVIPDPRWQNPEGAAELLAKLENEPGIEQGKLDLQWLTRLQGIMNLLRHTITGIAVLLLSAVLLIVGNTLRLNILNQRSEIEVLKLVGATDAFIHRPFLYTGIWFGVIGGMLAWWLTEVMVIWSEGVVKELAGLYNSNFRLVGMGAFDGFNLILLGALLGLIASWFSVHRHIRDIEPS
>CP026226.1|AUV16597.1|1729770_1730439_-|cell-division-ATP-binding-protein-FtsE
MIRFDKVSKVYSGGHQALQKVSFHLRKGEMAFLTGHSGAGKSTLLKLISVMERPTDGRVFFHGDDVSHIQRSQIPYVRRQIGMIFQDHRLLMDRTVFDNVALPLVIDGYSHGDINKRVAAALDKVGLLGKERYQPRMLSGGEQQRVGIARAIVNKPPLLLADEPTGNLDPQLSMDIMRLFEEFNRFGVSVLIATHDLGLIARMRYRTLTLKAGRMYSSGEDR
>CP026226.1|AUV16598.1|1730661_1732404_-|signal-recognition-particle-docking-protein-FtsY
MAKGLFSWLGFGRKKEEAEAVPSQAPDATPAVVESEAAAVPAPVADVAPADAPAAKPEALLSGPDEGPLVVEEPEGELEPVIVNEALISTEAQVADEAIVAAEARALEEARIATEARAAEEDCIAAEARAAEEARIAAEARAAEEARVAAEARAAEEARIAAEARAAEEARIAAEARAAEEARIAAEARAAEEARLAAEARAAEEARIAAEARAAEEARVAAEAQAAEEARVAKEAQRAEDLRLVAAMEAEAAALAALPLAAKVDDDTQEKPQREGFFARLKRSLVRTRENIGSGFFGLFSGKKIDDDLFEELETQLLTADLGVDTTTRIIEGLVQHADRKQLKDAEALYGLLKQDMGEMLAKVEQPLVIDTSKKPYVILMVGVNGVGKTTTIGKLAKQFQAEGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIYDAIEAARSRGADVLIADTAGRLQNKSNLMEELKKVVRVMKKLDDAAPHEIMLTLDAGTGQNALSQAKLFSEAVGLTGITLTKLDGTAKGGVIFAVADKFQIPIRYIGVGEGIDDLRPFVANDFIEALFSREE

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Crispr_ID: CP026226_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026226_5

2735368-2735471

Orphan

Consensus_repeat	Method
ATGAGTGATGCTATCGAGCTCAGTCTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026226_5

>merge|CP026226|5|2735368-2735471|CRISPRCasFinder
ATGAGTGATGCTATCGAGCTCAGTCTGTTGGATGAAGTAGAGCGCCAACCAGCTCCCGAACCGAAAGAGAAAATCACATGAGTGATGCCATCGAGCTCAGTCTG

>CP026226|5|5|2735368-2735471|CRISPRCasFinder
ATGAGTGATGCTATCGAGCTCAGTCTG	TTGGATGAAGTAGAGCGCCAACCAGCTCCCGAACCGAAAGAGAAAATCAC
ATGAGTGATGCCATCGAGCTCAGTCTG

Protein	Signature genes	Signature genes Name	Protein_function
CP026226.1\|AUV17351.1\|2726936_2727383_+\|DUF1249-domain-containing-protein	unknown	unknown	gnl\|CDD\|182921
CP026226.1\|AUV17363.1\|2746503_2747856_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|225174
CP026226.1\|AUV17366.1\|2749353_2750142_+\|TatD-family-deoxyribonuclease	unknown	unknown	gnl\|CDD\|238635
CP026226.1\|AUV17361.1\|2743943_2744312_-\|glyoxalase	unknown	unknown	gnl\|CDD\|319944
CP026226.1\|AUV19131.1\|2730054_2730306_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377931
CP026226.1\|AUV17352.1\|2727410_2728229_+\|3',5'-cyclic-AMP-phosphodiesterase	unknown	unknown	gnl\|CDD\|182997
CP026226.1\|AUV17354.1\|2728828_2729452_+\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|240029
CP026226.1\|AUV17362.1\|2744845_2746273_+\|ammonia-channel-protein	unknown	unknown	gnl\|CDD\|182630
CP026226.1\|AUV19132.1\|2741935_2743140_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|181829
CP026226.1\|AUV17364.1\|2747965_2748478_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP026226.1\|AUV17356.1\|2730298_2731165_+\|HlyD-family-secretion-protein	unknown	unknown	gnl\|CDD\|224482
CP026226.1\|AUV17357.1\|2731166_2733170_+\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|377393
CP026226.1\|AUV17365.1\|2748698_2749313_-\|prepilin-type-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|225076
CP026226.1\|AUV17358.1\|2733283_2735194_+\|DNA-topoisomerase-IV-subunit-B	unknown	unknown	gnl\|CDD\|235501
CP026226.1\|AUV17355.1\|2729488_2729893_+\|GFA-family-protein	unknown	unknown	gnl\|CDD\|226314
CP026226.1\|AUV17353.1\|2728238_2728826_+\|esterase-YqiA	unknown	unknown	gnl\|CDD\|182945
CP026226.1\|AUV17360.1\|2738765_2740379_-\|IS1634-like-element-ISAs25-family-transposase	unknown	unknown	gnl\|CDD\|227708
CP026226.1\|AUV17350.1\|2726126_2726837_+\|ADP-ribose-diphosphatase	unknown	unknown	gnl\|CDD\|182682
CP026226.1\|AUV17368.1\|2751753_2751924_+\|XapX-domain-containing-protein	unknown	unknown	gnl\|CDD\|274620
CP026226.1\|AUV17367.1\|2750355_2751630_+\|NupC/NupG-family-nucleoside-CNT-transporter	unknown	unknown	gnl\|CDD\|224883

Protein	Function_ID	Function_description	E-value
CP026226.1\|AUV17351.1\|2726936_2727383_+\|DUF1249-domain-containing-protein	gnl\|CDD\|182921	PRK11039, PRK11039, DUF1249 family protein.	9.98514e-59
CP026226.1\|AUV17363.1\|2746503_2747856_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	3.23132e-153
CP026226.1\|AUV17366.1\|2749353_2750142_+\|TatD-family-deoxyribonuclease	gnl\|CDD\|238635	cd01310, TatD_DNAse, TatD like proteins; E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity.	1.108e-90
CP026226.1\|AUV17361.1\|2743943_2744312_-\|glyoxalase	gnl\|CDD\|319944	cd08356, VOC_CChe_VCA0619_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. uncharacterized subfamily of vicinal oxygen chelate (VOC) family contains Vibrio cholerae VCA0619 and similar proteins. The VOC superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	3.3038e-64
CP026226.1\|AUV19131.1\|2730054_2730306_+\|hypothetical-protein	gnl\|CDD\|377931	pfam07869, DUF1656, Protein of unknown function (DUF1656). This family contains bacterial proteins, many of which are hypothetical. Some proteins in this family are putative membrane proteins.	5.36921e-06
CP026226.1\|AUV17352.1\|2727410_2728229_+\|3',5'-cyclic-AMP-phosphodiesterase	gnl\|CDD\|182997	PRK11148, PRK11148, cyclic 3',5'-adenosine monophosphate phosphodiesterase; Provisional.	3.80519e-142
CP026226.1\|AUV17354.1\|2728828_2729452_+\|NUDIX-domain-containing-protein	gnl\|CDD\|240029	cd04672, Nudix_Hydrolase_14, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	1.16821e-62
CP026226.1\|AUV17362.1\|2744845_2746273_+\|ammonia-channel-protein	gnl\|CDD\|182630	PRK10666, PRK10666, ammonium transporter AmtB.	4.80007e-178
CP026226.1\|AUV19132.1\|2741935_2743140_+\|IS3-family-transposase	gnl\|CDD\|181829	PRK09409, PRK09409, IS2 transposase TnpB; Reviewed.	5.96666e-143
CP026226.1\|AUV17364.1\|2747965_2748478_+\|N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.06133e-14
CP026226.1\|AUV17356.1\|2730298_2731165_+\|HlyD-family-secretion-protein	gnl\|CDD\|224482	COG1566, EmrA, Multidrug resistance efflux pump [Defense mechanisms].	4.16717e-84
CP026226.1\|AUV17357.1\|2731166_2733170_+\|FUSC-family-protein	gnl\|CDD\|377393	pfam04632, FUSC, Fusaric acid resistance protein family. This family includes a conserved region found in two proteins associated with fusaric acid resistance, FusC from Burkholderia cepacia and fdt-2 from Klebsiella oxytoca. These proteins are likely to be membrane transporter proteins.	2.68382e-164
CP026226.1\|AUV17365.1\|2748698_2749313_-\|prepilin-type-cleavage/methylation-domain-containing-protein	gnl\|CDD\|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	6.15397e-08
CP026226.1\|AUV17358.1\|2733283_2735194_+\|DNA-topoisomerase-IV-subunit-B	gnl\|CDD\|235501	PRK05559, PRK05559, DNA topoisomerase IV subunit B; Reviewed.	0
CP026226.1\|AUV17355.1\|2729488_2729893_+\|GFA-family-protein	gnl\|CDD\|226314	COG3791, COG3791, Uncharacterized conserved protein [Function unknown].	3.03322e-22
CP026226.1\|AUV17353.1\|2728238_2728826_+\|esterase-YqiA	gnl\|CDD\|182945	PRK11071, PRK11071, esterase YqiA; Provisional.	2.49084e-89
CP026226.1\|AUV17360.1\|2738765_2740379_-\|IS1634-like-element-ISAs25-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	2.95346e-57
CP026226.1\|AUV17350.1\|2726126_2726837_+\|ADP-ribose-diphosphatase	gnl\|CDD\|182682	PRK10729, nudF, ADP-ribose pyrophosphatase NudF; Provisional.	5.64534e-115
CP026226.1\|AUV17368.1\|2751753_2751924_+\|XapX-domain-containing-protein	gnl\|CDD\|274620	TIGR03510, conserved_hypothetical_protein, XapX domain. This model describes an uncharacterized small, hydrophobic protein of about 50 amino acids, found between the xapB and xapR genes of the E. coli xanthosine utilization system, and homologous regions in other small proteins, such as the N-terminal region of DUF1427 (pfam07235). We name this domain XapX, as it comprises the full length of the protein encoded between the genes for the well-studied XapB and XapR proteins. [Unknown function, General].	1.71552e-10
CP026226.1\|AUV17367.1\|2750355_2751630_+\|NupC/NupG-family-nucleoside-CNT-transporter	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	0

>CP026226.1|AUV17358.1|2733283_2735194_+|DNA-topoisomerase-IV-subunit-B
MSTQYNADAIEVLNGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHARNLEVILHEDQSLEVIDDGRGMPVDIHPEEGVSGVELILCKLHAGGKFSNKNYQFSGGLHGVGISVVNALSDRVEVTVRRDGQVYDIAFERGDKVSDLTITGTCGRRNTGTRVRFWPEARYFDSPRFSVSKLEHLLKAKAVLCPGLTIKFLDKNTGIKLEWCYEDGLKDYLIDAVKQFTCLPEQPFVGSFSSEQSAVDWALCWLPEGGECLAESYVNLIPTALGGTHVNGLRQGLLDAMREFCEFRNLLPRGVKLTPEDIWDRCAYILSIKMQDPQFAGQTKERLSSRQSSAFVSGVVKDAFSLYLNSNTELAEQLAELCISSAQRRMRAAKTVVRKKITQGPALPGKLTDCGCADPMQGELFLVEGDSAGGSAKQARDREFQAIMPLRGKILNTWEVEAGQVLASQEVHDISVAIGLDPDSDDLSGLRYGKVCILADADSDGLHIATLLCALFVKHFRTLVEKGHVYVAMPPLYRIDIGKEVFYALDEDEKNGVLQRVEAEKKKGKVMVTRFKGLGEMNPKQLRETTMDPNTRRLVQLTMGAEGGAEGEDGDETLQLMDMLLAKKRAGDRREWLEEKGNLAII
>CP026226.1|AUV17357.1|2731166_2733170_+|FUSC-family-protein
MIPSLWRQTPWGKANGGQWRYALRNALAMCLSLWLAFVLQLDSPYWAMTSAAVVSFPTVGGVISKSLGRVVGSLIGAMAAVMITGLGIGDPWLFSLLIALWLGGCTYISNHHQNNVSYGFALAGYTAAIIAFSCVNLTDPQHIFDIAQARVSEVIVGILCGGLMMMILPSFSDGETLLDSLGKSQTRLLEHAQLLWLGETGADVRTAHEGVIGQILTLNVLRIQAVWSHHRLRRHNQLLNYLLHRQLRMVSLISGLRRMLQHWPEDAVDPAPMLAAVLRELGQGGCDKLRIARLMAPFVARSGDDYRCQAFWLRLRHFCWSYLECQRWLERLARHDGQEWPAPPRHSSLTSHTDGLEAAYNGGRTFLCVMLGCTFWIHSQWDAGAAALTLLAICCVLYSATPAPAKGAQTMLKAIVLLSFICFGVKFGLMIRIDDFWIFCALLFPALITLQLLKLQRPQGAALWGQLIVLLGSFLAITNPPSYDYLAFVNSSLAQALGVMSAGLAFQLLRPSSDRRKSRRLMHRLRRDFVDQLAPAPHQSEGEFESRVYHAVSQLSQSQDQGARLWVLRWGVVLLNCSHIVWQLRLWRSRDPALYLVRDGCLRCLKGILTEGGVQHETLGRTLAELDRISQGLGEHADPAARALAGLVWRLHCSLSQLVQALPGEPA
>CP026226.1|AUV17356.1|2730298_2731165_+|HlyD-family-secretion-protein
MAKSPLATLKYFSTLLVFALALVSLWWLWNDYMQGPWTRDGKVRAELVSITPQVSGKIVRIGVKDNQLVKAGDLLFTLDPEPYRIALDNASAALAKARSDLDKAEHEANRRQSLSRTVISAEAVDESRLNAQAMKAAYEVAQANLEQARWSLARTEVHAASDGYITNLQARVGNYATAGVPLVALIDTHSFYVQGYFEETKLRHIAPGKPAEVVLYSGDRVLRGEVESIGRAIHDQSLEGSEGLLLDVKPNVPWVRLAQRVPVRIRLLAIPPDLVLIAGTTCTITIGD
>CP026226.1|AUV19131.1|2730054_2730306_+|hypothetical-protein
MSSLPTGGTPVTTASALPDLILGASLYFPPLFKAVLLGLLGWLPLHHLLRDWLYGGEVWHPLLMDLSLFILAVSGALWILLHG
>CP026226.1|AUV17355.1|2729488_2729893_+|GFA-family-protein
MITRIGNTPIQKKHKASCHCGAVVLELTLPDGVVDPRRCDCSFCRRRGAIVASVPLSGIRILQGEAALRCYQFNTRTAKHYFCSVCGIYTHHQRRSNPAEYGYNLACLEGVNPFDLGEVPTRDGVHHPADTVTD
>CP026226.1|AUV17354.1|2728828_2729452_+|NUDIX-domain-containing-protein
MQPPLAAFLEQVLATAQAGLTYSRDPFDIARFEALRAATVTLIASQSELAPDAIGDWIALDSGYPTPKLDVRAFIQNDAGHVLLVQERSDGCWTLPGGWCDVGDSPAGAVVREVSEETGLACRAVQLLALFDKLKHPHPPQLPHAHKAFFLCEVTGGALLTDTDETKGAGYFPIDALPELSRHRVVASQLRTLHDHLSQGRGDTLFD
>CP026226.1|AUV17353.1|2728238_2728826_+|esterase-YqiA
MKPVLLYLHGFNSSPGSAKAQQMAAWVAENRPDIEVVIPAQPNTPAAAWAAIEQAIADLKARHGSALRLGAVGSSLGGFMATRVSERYGCRAALINPAVRPHELLCDYLGPQTNPYSGERYELLPGHMDELRALAVPVTAPERLWVLQQQEDEVLDYRKALDEYRFARLSLECGGDHAFTGFERYPAQIVRFLGL
>CP026226.1|AUV17352.1|2727410_2728229_+|3',5'-cyclic-AMP-phosphodiesterase
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQANEHPFDLILATGDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQVILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNADDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDGFALDESGPGWRYLTLHPDGRVASQVWRLPLGQFVPDPNATGY
>CP026226.1|AUV17351.1|2726936_2727383_+|DUF1249-domain-containing-protein
MSLVQSPMKRYVPDLMSLQRTCEVNYMALMKLLPPGGSVGAERRYQVGNGLQFQLTVTEESRFTSQVILAQHNPELPSYLQARIEIRLYHDVRMAEVCAAQQISMLQPRYDYPNQKMHHRDEKEQVNLFLADWLRFCLKHGTSLINIL
>CP026226.1|AUV17350.1|2726126_2726837_+|ADP-ribose-diphosphatase
MNVHSCPRILWSNQAKSSWQESRMSQQALPQTCHYSSDDVKIIEKSAGYNGFFKVNVYRLQHRLFAGGWNAPIVRELFERGHAAALLPYDPVRDEIVLVEQFRIGAMETSATPWLLELVAGIIDEGETAEAVVRREAVEEAGIEVGRCEHAISYLVSPGGSTERIEVFVGEVDSSQAKGIHGLAEEGEDIRVHVVSREQAYAWLKEGRIDNAASVIALQWLALNHGELRARWLAGR
>CP026226.1|AUV17360.1|2738765_2740379_-|IS1634-like-element-ISAs25-family-transposase
MAAPAISIRNLDHLGLVAALCQELGIARMIDALLPKTPPFKVSHGEALVAMIVNGLGFHSSTLHMFPQFFANKPVERLIGPGICADDLNDDVLGRCLDALFEADVSALYQVMAAQVVERLGLKSTAVHLDITSFHVDGAYDCADGDLVGKLQLVRGYSRDHRPELNQVILELICENQAGLPVYMQALSGNSNDTKAFAQTVRRHLSSLKAAQECRYLVGDAALYCADTLQLLAQQQQLFVTRVPVTLNEAKQAVATIGAQPLTALGNGYHGRWQHANYAGVAQRWLLVRSEQASHREQQTLAKNLLKDSTRELKAFAKLCARRFACEADAQAELSCFTASLMLLQLDAEVVGEPVYTGRGRPKRGEEPIGHQFQITGLAATSLACVEEAHNQTGVFILATNDHSDTLTMAELLATYKAQQNVERGFRFLKSPEFLTSSLYLKKPERIEALLMVMTCSLMIYAALEHRIRQGLVEQNRSVADMKKKPTQQPTARWIFLRFGGIHEYRLGEAPPQVTELTGDQQIILEVLGERYRQIYS
>CP026226.1|AUV19132.1|2741935_2743140_+|IS3-family-transposase
MVEVLTGAERRRRRTPQEKISIVQQTFEPGMTVSHVARLHDVNANQLFKWRKQFQEGSLTAITAGEDVVPASELAAAIKQIRELQRLLGKKTMENEILKEAVEYGRGKKMDCACALVAGGRRLSAVSQALNVSRAQLSVRVHRKPDWQDGRHHRQRDDAVLLGRIMEAMAELPSYGYRRVWALLRRQSEATRQPVVNAKRVYRVMRDHDLLLERKPAAPLTQRAHKGRVAVKESNRRWCSDGFEFRCDNGEKLRVTFAMDCCDRETLDWAASTGGYDSDTVQDVMLRSVERRFGDSLPASPVEWLTDNGAAYRAHETRAFAREIGLEPRTTAVRSPQSNGIAESFVKTMKRDYIEMMPKPDSRTAVGNLAIAFEHYNEHHPHSALGYRSPREFLRSRVSQP
>CP026226.1|AUV17361.1|2743943_2744312_-|glyoxalase
MPNLNVTEIKAFVPARDFTLSKQFYQDLGFTLASGGDGVAYFHLGNASFLLQDGNPPGLAEQLMMHLLVEDVAAWQEQVATSQLARRYGVRVTELVTQPWRMKEFCLYDPSGVLWRIAQNID
>CP026226.1|AUV17362.1|2744845_2746273_+|ammonia-channel-protein
MFKRLVMTGLLALAATMAAPGWAEEVAAQADVVQAAATVTINKGDNTWLMVAAALVILMSVPGLALFYGGLVRAKNMLSVLMQVFTLFCLITVLWVVYGYSLAFTEGGAFYGSFDKVLLMGVTPDSIAATFSKGVGISEFIYVVFQGAFAAITCGLIVGGFAERMKFSAVLLFAVIWFTFAYIPMAHMVWYWAGPDAYTDAAAAEAAGATAGYLFQHGALDFAGGTVVHINAAVAGLVGAFMVGKRVGYGRDPMTPHSLTMTMIGAALLWFGWFGFNAGSSLEANGTAALAFANTWIAPAAAALSWTFAEWAMKGRPSLLGAVSGAVAGLVAITPAAGFVGVGGALIIGLLSGVAGLWGVHGLKRLLGADDSLDVFGLHGVCGILGAVLTGVFASPDLGGTGVWDYVTNQVAEGYSILAQVKIQVIGVGVTVVWTALVSAVAYKLVDLLIGLRVKEDAEREGLDVTSHGEKAYSH
>CP026226.1|AUV17363.1|2746503_2747856_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MPLVGHQHQIDILELTDKGDGKGRLFDRPLFVEGLLPGEQALVELTEVKPNYLHGKLVELTQPSADRVADFCPNTECGGCQVRPLAYPAQLKLKQSLVQSALEQVGLGDAVVNPILGMETPFAYRNKAQYAVRGCDAGAEIGFYRKHSHDLITADDCAVQDSLHVELNARVRNWMREHDIAAYDEVAHTGCVRNLMTRKGFKSGELMVVLVTLSEELPFEAELLAALQDLPITTLVQNINEARTNRILGDNNRVLLGSGVIRDKIHELEFEISPLSFFQNNPSQTDVLYSKALEYCELTGNETVFDIYCGIGTISLFLAGKAAKVVGIESVESAISDARRNAALNGIEQTEFHVGKAEQLMPALHAEGVSADVVVMDPPRKGCDKAVLQTLVAMAPRRLVYVSCNPQTLARDLAWLVKQGFVLDEVQPVDMFPHSMHVEAVARLSLPAKA
>CP026226.1|AUV17364.1|2747965_2748478_+|N-acetyltransferase
MMIRMAGVEDAAVLDRFFGQLDRETRFMLYEAGERPSDIEGQRRRLEAMAAAPNQAMWLLELAGEVQGFAALLGGGLARNRHCALVVMGLRSGARGQGWGERLLRTLIATARDLGIHRLELGVMTHNEVAHALYRKCGFVEEGVRRQAYRLDEGYVDEISMGLLLPLDRP
>CP026226.1|AUV17365.1|2748698_2749313_-|prepilin-type-cleavage/methylation-domain-containing-protein
MPTHVSRGFTLIELVLVIIVLGILAVTALPRFINIQDDGLKSSVSATAGSFASAARLAHAGWAVKVKGEPLALYNFSGMGRQDLDINSHGWPVGTKEDQGGQGPDTVFPGGDSDQISVSSRNDCESLFGALLDTDLTVADELHQDSDSDYISRLIPADAQADGALRHDNCRYTLRSSVGRFPAYPDGLSFDYNSVTGAVTRQFQ
>CP026226.1|AUV17366.1|2749353_2750142_+|TatD-family-deoxyribonuclease
MELIDTHCHLDFPVFDADREALLTRWRQLGVGEYIIPAVGEENWGRVVALAGRHDDIRYGLGIHPWYVGKQPRDALTRLETLLASRPRGLVAVGECGLDLRSHVPQEGQVEMFEAQVRLAMAHALPLIVHSVRANDTVAKILRRFTPPQGGVIHAFSGSLHQAEVFWQLGFRLGIGGVISYERANKTREAIRQMPLEALLLETDAPDMPLQGQQGEVNTPASLPTIARLLAQLRQQPLEDVISVLHDSTRRLFPPGNHEINI
>CP026226.1|AUV17367.1|2750355_2751630_+|NupC/NupG-family-nucleoside-CNT-transporter
MNLIMGLVGMATLILIAVLFSSNRKAIKIRTVGGAFAIQAGLGAFVLYVPVGRDILVGVSDAVSSVIGYGQNGIEFLFGGLVGNKMFEVFGGGGFVFAFRVLPVIIFFSSLIAVLYYLGIMQWVIKLLGGGLQKVLGTSRTESLSATANIFVGQTEAPLVVRPFISKMTDSELFAVMCGGLASVAGSVLAGYASMGVKMEYLIAASFMAAPGGLLFAKLLVPETETPSYDENTAEGELDDKPANVIDAAAAGASAGLQLALNVGAMLLAFIGLIAMINGIFSGVGGWFGYPQLSLELLLGWLFSPLAFLIGVPWSEAVVAGSFIGQKLVVNEFVAYLNFAPYLKDEVLINGVAMSEHTKAIISFALCGFANLSSVAILLGGLGSMAPNRRGTIAKFGLKAVLAGSLSNLMSATIAGFFLALSGM
>CP026226.1|AUV17368.1|2751753_2751924_+|XapX-domain-containing-protein
MNEVLLAMAAGFIVGVLFSFLKLPIPAPPVLSGVMGIVGVYLGGIAYSWILTRFFS

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Crispr_ID: CP026226_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026226_6

2999524-2999629

Orphan

Consensus_repeat	Method
CCCTTCTCCCCTTGCGGGAGCCATGGTTGTTTCTGGGGGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026226_6

>merge|CP026226|6|2999524-2999629|CRISPRCasFinder
CCCTTCTCCCCTTGCGGGAGCCATGGTTGTTTCTGGGGGAGGTCGCACGCCGCTTGGTTGTTTGTTCCCTTCTCCCCTTGCGGGAGCCATGGCTGTTTCTGGGGGA

>CP026226|6|6|2999524-2999629|CRISPRCasFinder
CCCTTCTCCCCTTGCGGGAGCCATGGTTGTTTCTGGGGGA	GGTCGCACGCCGCTTGGTTGTTTGTT
CCCTTCTCCCCTTGCGGGAGCCATGGCTGTTTCTGGGGGA

Protein	Signature genes	Signature genes Name	Protein_function
CP026226.1\|AUV17575.1\|3005672_3006713_-\|IS481-family-transposase	unknown	unknown	gnl\|CDD\|366234
CP026226.1\|AUV17568.1\|2997671_2998793_-\|alkene-reductase	unknown	unknown	gnl\|CDD\|239243
CP026226.1\|AUV17569.1\|2998876_2999443_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
CP026226.1\|AUV17561.1\|2986811_2988425_+\|DUF3763-domain-containing-protein	unknown	unknown	gnl\|CDD\|184118
CP026226.1\|AUV17570.1\|2999719_3000097_-\|endonuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|238509
CP026226.1\|AUV17578.1\|3009972_3010578_-\|transporter	unknown	unknown	gnl\|CDD\|224199
CP026226.1\|AUV17574.1\|3004684_3005536_-\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|238038
CP026226.1\|AUV17563.1\|2991185_2993048_+\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
CP026226.1\|AUV17576.1\|3008670_3009066_-\|hypothetical-protein	unknown	unknown	unknown
CP026226.1\|AUV17562.1\|2989985_2990990_-\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
CP026226.1\|AUV17572.1\|3001531_3002629_+\|agmatine-deiminase	unknown	unknown	gnl\|CDD\|184135
CP026226.1\|AUV17566.1\|2996093_2996555_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|100048
CP026226.1\|AUV17564.1\|2995050_2995389_+\|steroid-delta-isomerase	unknown	unknown	gnl\|CDD\|226913
CP026226.1\|AUV17565.1\|2995462_2995912_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP026226.1\|AUV17579.1\|3010594_3011422_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
CP026226.1\|AUV17573.1\|3002765_3004469_+\|amidase	unknown	unknown	gnl\|CDD\|180626
CP026226.1\|AUV17577.1\|3009300_3009810_-\|hypothetical-protein	unknown	unknown	unknown
CP026226.1\|AUV19151.1\|2993292_2994882_+\|peptide-chain-release-factor-3	unknown	unknown	gnl\|CDD\|179105
CP026226.1\|AUV17567.1\|2996551_2997478_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
CP026226.1\|AUV17571.1\|3000473_3001385_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109

Protein	Function_ID	Function_description	E-value
CP026226.1\|AUV17575.1\|3005672_3006713_-\|IS481-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	4.39564e-19
CP026226.1\|AUV17568.1\|2997671_2998793_-\|alkene-reductase	gnl\|CDD\|239243	cd02933, OYE_like_FMN, Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Members of OYE family include 12-oxophytodienoate reductase, pentaerythritol tetranitrate reductase, morphinone reductase, and related enzymes.	5.17263e-171
CP026226.1\|AUV17569.1\|2998876_2999443_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.75744e-08
CP026226.1\|AUV17561.1\|2986811_2988425_+\|DUF3763-domain-containing-protein	gnl\|CDD\|184118	PRK13531, PRK13531, regulatory ATPase RavA; Provisional.	0
CP026226.1\|AUV17570.1\|2999719_3000097_-\|endonuclease-domain-containing-protein	gnl\|CDD\|238509	cd01038, Endonuclease_DUF559, Domain of unknown function, appears to be related to a diverse group of endonucleases.	3.62523e-42
CP026226.1\|AUV17578.1\|3009972_3010578_-\|transporter	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	3.02266e-11
CP026226.1\|AUV17574.1\|3004684_3005536_-\|HNH-endonuclease	gnl\|CDD\|238038	cd00085, HNHc, HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.	1.25855e-07
CP026226.1\|AUV17563.1\|2991185_2993048_+\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	8.44032e-57
CP026226.1\|AUV17562.1\|2989985_2990990_-\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.04617e-48
CP026226.1\|AUV17572.1\|3001531_3002629_+\|agmatine-deiminase	gnl\|CDD\|184135	PRK13551, PRK13551, agmatine deiminase; Provisional.	0
CP026226.1\|AUV17566.1\|2996093_2996555_-\|N-acetyltransferase	gnl\|CDD\|100048	cd03358, LbH_WxcM_N_like, WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization and transacetylation reactions of keto-hexoses. It contains an N-terminal LbH domain responsible for the transacetylation function and a C-terminal isomerase domain. The LbH domain contains imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X), typical of enzymes with acyltransferase activity.	1.38434e-45
CP026226.1\|AUV17564.1\|2995050_2995389_+\|steroid-delta-isomerase	gnl\|CDD\|226913	COG4538, COG4538, Uncharacterized conserved protein [Function unknown].	6.63592e-22
CP026226.1\|AUV17565.1\|2995462_2995912_+\|N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.2917e-11
CP026226.1\|AUV17579.1\|3010594_3011422_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	3.11411e-26
CP026226.1\|AUV17573.1\|3002765_3004469_+\|amidase	gnl\|CDD\|180626	PRK06565, PRK06565, amidase; Validated.	0
CP026226.1\|AUV19151.1\|2993292_2994882_+\|peptide-chain-release-factor-3	gnl\|CDD\|179105	PRK00741, prfC, peptide chain release factor 3; Provisional.	0
CP026226.1\|AUV17567.1\|2996551_2997478_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	6.83839e-20
CP026226.1\|AUV17571.1\|3000473_3001385_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	8.18753e-55

>CP026226.1|AUV17569.1|2998876_2999443_+|TetR/AcrR-family-transcriptional-regulator
MRSAEYDRDAVLRNAMEAFRAKGYAKTTMQELVAATGLHPGSLYAAFGNKRGLLLAAVDHYVAEKGALRRRCLAQPSPLAGLHAYLEQVVDDALQGSCLLTRTLMELAEQDEELHLRFKAIYGELEQDLAGQLALAKAKGELAKEGDIPTLTAFLQVHIQGLVTFAQCHPDRPLLAGVVARMMSALRA
>CP026226.1|AUV17568.1|2997671_2998793_-|alkene-reductase
MLAQKILAHKPKNVLNARSRITPSGQTIMNTLFQPYRLNDTLTLANRFMMAPLTRCMAGPGLVPTEQMAAYYGRRADIGLIISEATIIRPDGQGYPNTPGLYSAEQIAGWKKVTSAVHANGGKIFAQLWHVGRLSHPFFHHAEVLAPSAVAHEGTVPRMRELVYQVPRALTGSEIAQLVEDYAQAAANAIEAGFDGVEIHGANGYLIDQFLHHASNLRTDNYGGSPENMSRFALEVVDAIAARIGGDRTGLRLSPGAYVHLEGDARDRAVFDHLLAELNQRTLAYLHLGIFDDSLTFDYLDGRASDYLRARYDGHLVGVGNYSAETALEAIEADRFDLVAIGRPLIANPDYFAKVKQGDALVPYADTMLAELV
>CP026226.1|AUV17567.1|2996551_2997478_-|MarR-family-transcriptional-regulator
MDPRPLRALSRELVRELGMLSQQCGSLALSPLEAHLLIELENGPATNQQLAERLRIDKSNASRPLARLAERELIAWQPHPSDGRSKEASLTEPGKAQLEELHRQMDETMAGALAQLSPAECEQIWEGMRLYRSALSRARRQQGFVIRPITPADNPRIAAVVRAVSAEYGLTADKGYGVADPNLDFLHETYQGERSRYWVIEGPDGAILGGGGIAPLAGAADVCELQKMYFLPALRGLGLGRRLVLQALAEARALGYQRCYLETTAVLREATALYESLGFEHLPGPLGCTGHDACEICMVLALDGKEGR
>CP026226.1|AUV17566.1|2996093_2996555_-|N-acetyltransferase
MSEPTRLSVGIRDVSFGERVKLVEPVNLYGCTLADDVFVGPFVEIQSNVSIGRATRIQSHSFICEHVTIGERCFIGHGVMFANDLFQSGAPDPDPASWGRTHIGDGVSIGSNATILPVRICQGAVIGAGAVVTRDITVPGTYAGNPARLLRTF
>CP026226.1|AUV17565.1|2995462_2995912_+|N-acetyltransferase
MQIFKATLAHIEETSRLFDAYRQFYGQAPDSDEATRFIGERLQGADSVIFLARNEAGECAGFVQLYPAFSSVAMKRMWYLNDLYVVESARQQGVARALLKRVASFARETDALTVKLATAVSNQPAKLLYESEGYQKVIAFDHYTQRVGA
>CP026226.1|AUV17564.1|2995050_2995389_+|steroid-delta-isomerase
MSVTQPVEAQFAAYNAHDLDAFVACFAPDFKGYRMPTETPSTVGKGALRAFYAQHRFNNPLLKAELLSRTVMGNKVFDHELIHGLSPEPIESVAVFEVKEGLIQTAWFYFPS
>CP026226.1|AUV19151.1|2993292_2994882_+|peptide-chain-release-factor-3
MMSAEFLSEVSKRRTFAIISHPDAGKTTITEKVLLFGQAIQRAGTVKGRGSGQHAKSDWMEMEKQRGISITTSVMQFPYADCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDREVRDPMEVMDEVERELNIMCAPITWPIGCGKSFKGVYHLYKDETYLYQSGQGHTIQEKRVVKGLNNPELDAAIGDDLAAQLRGELELVQGASPEFDHDAFIAGEMTPVFFGTALGNFGVDHMLDGLTDWAPAPMPRKAESREVVATEEKFSGFVFKIQANMDPKHRDRIAFMRIVSGTYSKGMKMRHVRIGKDVNISDAVTFMAGDREQAVEACAGDIIGLHNHGTIQIGDTFTQGEDLKFTGIPNFAPELFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVFRPLISNDLIVGAVGVLQFDVVVSRLKSEYNVEAIYEAVNVATARWVEGSDVKKFEEFKRKNEVNLALDGGDNLTYIAPTMVNLRLAQERHPDVHFRQTREH
>CP026226.1|AUV17563.1|2991185_2993048_+|GGDEF-domain-containing-protein
MKILMGGGLLLGVALAQATPLAGYELQLALQRLEESTMPVQVFRERVAALTAEQAHYPPEVQGRLARLQCWAQPSERDEEFRRAVAFAEQGLAQARARKDRVTEVGLLACRGYHRQLLGNMAGAGEDYDAALTLARRLGDERQRADILSLRGEMYSYQGELAEGLMDLIDAHQRYEALGLEAKGREVLANIANAYRRMGLYERAESYFKELEHDYRQLGVEEYLVDIHSQQGLLYIDTEEYDKALPLMAEAERYYLGSNQEGVLAWSRIELATILQKQGKPDQAMTKLDQAAASLHQGEGADSVTLGHWHLVMAEVLEALNRPGEALRHLDEAEPIFTREQNLRFLARVHETRARVLERQGHIQSALTSLKTYVETRQALELRLREQRSLQMRFEFDLARKELENQTLRSQQQLQAEKLKQLQERRYWQYLVVALLLVVMGTLVVHQRGRTRKMQRLAMTDELTGIHNRRQIQAKGRKWFTQAREEGKPLCVLLLDVDHFKKVNDQLGHHVGDRVLTAVAQCIEEQLRSLDRVGRNGGEEFLVLLPDTLLGEAVEVAERIRLAVACLEIEGVPADHPIHISIGCAQYKPEDDNLGELVRRADEAMYQAKLAGRNRVMTAR
>CP026226.1|AUV17562.1|2989985_2990990_-|GGDEF-domain-containing-protein
MTYEELREAYDRLLLENERLKRIADDAREKLDAAMDGTGLCIWQNHVPTGKLIIFNRRWGSMLGYQPKELSAHFDVWRAHLHPEDREQVLQAFFDHLEGKSPFYQAMHRMIGKDGKTTWVLDRGRVVERDDQGNPVRVMGTHIDITHEKEYEQQLAQLAHRDPLTGLFNRTALHRHFPGEYQAICFIDLDDFKLVNDNLGHRAGDELLVSLAQRLRHCCAEEVRLGRIGGDEFVLLLPWACDDPRTSHLARQCIDAIATPFELPNGDASVGLSMGIAAIRPQDDFGAALARADQAMYRVKRSGKRGFYIAQPSGQPLLDQEQVNERGLYHRPTL
>CP026226.1|AUV17561.1|2986811_2988425_+|DUF3763-domain-containing-protein
MPPLAQNTVRATPIHERLPRLLSALGEGLYERQDALRLGLLAALSGESVFLLGPPGIAKSLIARRLKLAFQDARHFEYLMTRFSTPEEVFGPLSIQALKEDGKYLRLTSGYLPEAEVVFLDEIWKAGPAILNTLLTAINERQFRNGDSQHPIPMRLLVTASNELPAPDSGLEALYDRMLVRVWMDRVQEKSNFQAMLASDGQSHQNLTPSVQIRGEEYDAWQDAIEQVRLPDACFELIYQLRQQLDSLLGHGCYVSDRRWKKAVRLIKASAFFNGRDEVAPLDLLLFKDCLWHDEASRTALLEMIGEFSRLYGYQQLALTRELLSLREQFKQLQGAVALRIGCKAVKRKQWFGRRARGTELPLANARPFGKLVHFQLLTPAPLDGSDPERLTGTLTFDRTLLSHWHPTGEALVGWPLGNPKEGHYELVLDEQLRLHVLDIQRQPVPLMLVERTPIPEVVMAPWLSALDDLTGQVNRVLQNLKGQRNLFDRHQPHLFVGDHWLRQVEDSFFVLSRDLERLGAELQQWRDRLPLLDAQG
>CP026226.1|AUV17570.1|2999719_3000097_-|endonuclease-domain-containing-protein
MAISNRVKQLWIGTKRTHPFAKRMRREATLAEQKLWLQLRDRRLAGVKFRRQMPIGPYIVDFISLEQRLIIEVDGSQHNEPAGRQHDGARTAYLNQQGFRVIRVWNNDVLSRMEAVLKLLLLSLR
>CP026226.1|AUV17571.1|3000473_3001385_-|LysR-family-transcriptional-regulator
MKLHQLDLNLLLAFDALMTQGSVTRAAESLFISQPAMSHSLGRLRAFLGDPLLVRTPQGMLPTPRAQRLHLGVQQALRLLEQQLWEEDEFAPRQSKRRFVLCTTDYVECVLIPPLIQRLRKLAPGVTIEIRILRDTLPEAELASGEIDLVLGFDEYMQVPGYLGKETWLTEPLAGLVRATLELEEERITLDQLIEMPHVFHSPLGTSEASLDRYLQSLGHSRTISVNSQSYMSAAAIVSQSDHLLVLPSMVAELLASHWPLKSLPLPDDVPDYHLNCVWHPVHAQQPALTWLKALMKDLVNPG
>CP026226.1|AUV17572.1|3001531_3002629_+|agmatine-deiminase
MSIKTMNTTPAADGFTMPAEWAHQQAVWMIWPFRPDNWREAGRFAQATFAKVADAIGGATPVFMGVPAQFMEQARGIMPAHVTLVEMASDDCWARDTGPTIVTNAAGECRGVDWGFNAWGGHKGGLYYPWNQDEEVAARMLEQHGMGRYDAPLILEGGSIHVDGEGTCLTTAECLLNENRNPHLTKEQIEAHLRDYLGVTSFIWLDEGVYMDETDGHIDNMCCFVRPGEVALHWTDDETDPQYARSLAALQVLEAAVDAKGRKLKVWKLPQPGPLYCTEEESAGVESGSGVPREAEGRLAGSYVNFLITNDRIVYPLLDAATDGEAQRILEEIFPEHKVVGVPAREILLGGGNIHCITQQIPSGK
>CP026226.1|AUV17573.1|3002765_3004469_+|amidase
MIEVTEVSIVELRAALESGRTTAVELVEAYQARIAAYDGPETPTRLNAVVVPNPDALKEAQASDARRARGETLGPLDGIPYTAKDSYLVKGLTAASGSPAFKDLVAQRDAFTVERLRAAGAICLGKTNMPPMANGGMQRGVYGRAESPYNADYLTAPFASGSSNGAGTATAASFAAFGLAEETWSSGRGPASNNGLCAYTPSRGVISVRGNWPLTPTMDVVVPYARTMADLLEVLDVVVADDADTRGDLWRMQPWVKLPKASEVRPASYLELAAKPDALKGKRLGVPRMFINKDELAGTSDNPGIGGPTGQRIHTRETVIALWEDARKALEAAGAEVIEVDFPLVSNCEGDRPGAPTVFNRGIVSPEFLNDELWELSGWAFDDFLRANGDPKLNKLADVDGPKIFPHDPGTLPNREGDLAAGMDEYVNMAKRGIKRFDEIPTVPDGLRGLEKTRKLDLEDWMDGLKLDAVLFPTVADVAPADADVNPASADIAWSNGIWVANGNLAIRHLGVPTVTVPMGVMADIGMPVGLTFAGRAYDDNNLLRVASAFESTGSKRMVPPRTPPLG
>CP026226.1|AUV17574.1|3004684_3005536_-|HNH-endonuclease
MLNVKYYETYYFCNVISNILMEQDSYLRDLHNFHGDGNILNMLQPFRKHSVFHDFLEFVIDDVTWDNTYDIDLEERQQLIKNNAHLPIINKHLKWDILPIELALTFHGLEYESFSSFLHERDKKFTTCDKDDIYDYLLELRLNGNFEQLIEHTSKEVFHVLFQNRVLMLVFNTMMANALEREHTVESKSDDLIRKNGKLKRKNIPSWVRKAVYFRDRGRCVLCNKDLSGTLNLDNVANYDHIVPLSNFGFNDISNMQLLCKECNQNDKHGGDATTSSFYHSWY
>CP026226.1|AUV17575.1|3005672_3006713_-|IS481-family-transposase
MTTNEKVARRKLSLLELAKELNNVSKACKLIGYSRQQFYEIRRNYQTYGAEGLLDKLPGCKGAHPNRVAPEIEQAILDYSLTRPTHGPLRVAQELALQGINVSAGGVRGVWQRHDLLSKHDRLLRLEKTHREQTIELNDEQIRLLERFSPEFRERQIEVHYTGELVAVDTFFVGALKGVGKVYLQTVLDCYSRHAWGRLYTSKLPVTSVHVLNETVLPFFEAHEARVYTILSDNGREFCGRPDHHPYELFLQLEGIEHRTTKVRRPQSNGFIERLHRTLLDEHFRIKGRTIWYESVEQMQTDLDSYLDHYNTQRPHQGRMMEGQTPYSMFKKGLKLIPKEVRTKVA
>CP026226.1|AUV17576.1|3008670_3009066_-|hypothetical-protein
MSFDKKHGEFIFNVQEHLVTCELIGPFNEEGMLAWIAQIKTVVNSLDGKRFCALVDHRQHQGVVLSALPHLQDIYGWLAQKNLVAIASLYSAKVLHHIALSCLSLTHPGHIQAFNDPQEAIAWLDAQYQAQ
>CP026226.1|AUV17577.1|3009300_3009810_-|hypothetical-protein
MDRYYKHLAISGLISFGGLALVLLLQTIPLMSNIMTAIFFAGSVGAVINNYYRLARLHDSGAIAHISQPRVIVTQFYVSLLFSGILGFIAYGLFASSLLQGDLFPKFKHMEHPYVSLQTLLTLASPATNLDAAKAVIWAFIAGFSERFVPNAIDALTKAVPPSGQDTPG
>CP026226.1|AUV17578.1|3009972_3010578_-|transporter
MIELLAYAIGIMYTPGPVNLIGLNAGLGGRTRASLGFFLGVGLAMFVLLLLFGWAGTRLVREDTLIYVSLVGCLYITYLAIKIASDSGELGANEAPTRPLGVRSGFVIQLLNPKAMIATLPITSIQFPAAQIHGWSLLPWSLLLGLLAAGAPGSYSMAGSLIGRHLQHPRWFRYFNLLMAALLLYSAMALAYQHVYLPLAG
>CP026226.1|AUV17579.1|3010594_3011422_-|AraC-family-transcriptional-regulator
MAQDNQFIFAHSQHLASLTALRVNMTEFRYDRHAHEEYSFGVTLAGRQNFFCHGGAHSSPAGSVIQFNPGDVHDGHAGDNASLDYTMLYIPPHELTPLFADAAGERAMGTYRLLKPLVRDEALSACILELAQAVRGQADSIEQEFALYRLATRVMQQAGRFEPNGRVSRIDRLLLQARDFIHAHFQQDISLADISAAANISKYHFLRLFRQQLGITPHQYVINCRINAARRALAAGESAQDLVYRYGFTDLSHLNRRFKRIYGMTPTQYSASLIR

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Crispr_ID: CP026226_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026226_7

3157602-3157757

Orphan

Consensus_repeat	Method
GTCTCCGACATCTGCGTTGCCCTGGTCGATCCTCGCGTGCGGTTTGGAGAGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026226_7

>merge|CP026226|7|3157602-3157757|CRISPRCasFinder
GTCTCCGACATCTGCGTTGCCCTGGTCGATCCTCGCGTGCGGTTTGGAGAGTAATCATGAGCCTGAACTCTGTTGCCATGCCGATGCTGATGTCAGCCCATATCGTCTCCGACATCTGCGTTGCCCTGGTCGATCCTCGCGTGCGGTTTGGAGAGT

>CP026226|7|7|3157602-3157757|CRISPRCasFinder
GTCTCCGACATCTGCGTTGCCCTGGTCGATCCTCGCGTGCGGTTTGGAGAGT	AATCATGAGCCTGAACTCTGTTGCCATGCCGATGCTGATGTCAGCCCATATC
GTCTCCGACATCTGCGTTGCCCTGGTCGATCCTCGCGTGCGGTTTGGAGAGT

Protein	Signature genes	Signature genes Name	Protein_function
CP026226.1\|AUV17680.1\|3165872_3166340_+\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|236395
CP026226.1\|AUV17671.1\|3150508_3151036_-\|MotA/TolQ/ExbB-proton-channel-family-protein	unknown	unknown	gnl\|CDD\|376576
CP026226.1\|AUV19165.1\|3161862_3162864_+\|dipeptide-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|236898
CP026226.1\|AUV17679.1\|3165314_3165428_+\|hypothetical-protein	unknown	unknown	unknown
CP026226.1\|AUV19162.1\|3150034_3150442_-\|biopolymer-transporter-ExbD	unknown	unknown	gnl\|CDD\|376792
CP026226.1\|AUV17673.1\|3152416_3153181_-\|DUF3450-domain-containing-protein	unknown	unknown	gnl\|CDD\|378764
CP026226.1\|AUV17668.1\|3140302_3140587_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373549
CP026226.1\|AUV19163.1\|3157767_3158805_+\|peptide-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226690
CP026226.1\|AUV17676.1\|3158887_3160705_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173862
CP026226.1\|AUV17678.1\|3163493_3164945_-\|aminoacyl-histidine-dipeptidase	unknown	unknown	gnl\|CDD\|349885
CP026226.1\|AUV17669.1\|3148135_3149371_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
CP026226.1\|AUV17677.1\|3163109_3163229_-\|hypothetical-protein	unknown	unknown	unknown
CP026226.1\|AUV19164.1\|3160730_3161768_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
CP026226.1\|AUV17670.1\|3149382_3150018_-\|energy-transducer-TonB	unknown	unknown	gnl\|CDD\|367555
CP026226.1\|AUV19161.1\|3144789_3147795_+\|chitinase	unknown	unknown	gnl\|CDD\|225862
CP026226.1\|AUV17682.1\|3167845_3168238_+\|Crl-family-RNA-polymerase-assembly-factor	unknown	unknown	gnl\|CDD\|369355
CP026226.1\|AUV19160.1\|3142443_3143874_+\|IS4-family-transposase-ISAeme22	unknown	unknown	gnl\|CDD\|280446
CP026226.1\|AUV17672.1\|3151046_3152420_-\|MotA/TolQ/ExbB-proton-channel-family-protein	unknown	unknown	gnl\|CDD\|376576
CP026226.1\|AUV17674.1\|3153283_3155890_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|366183
CP026226.1\|AUV17681.1\|3166514_3167783_+\|esterase-FrsA	unknown	unknown	gnl\|CDD\|235337

Protein	Function_ID	Function_description	E-value
CP026226.1\|AUV17680.1\|3165872_3166340_+\|xanthine-phosphoribosyltransferase	gnl\|CDD\|236395	PRK09177, PRK09177, xanthine-guanine phosphoribosyltransferase; Validated.	2.0924e-101
CP026226.1\|AUV17671.1\|3150508_3151036_-\|MotA/TolQ/ExbB-proton-channel-family-protein	gnl\|CDD\|376576	pfam01618, MotA_ExbB, MotA/TolQ/ExbB proton channel family. This family groups together integral membrane proteins that appear to be involved translocation of proteins across a membrane. These proteins are probably proton channels. MotA is an essential component of the flageller motor that uses a proton gradient to generate rotational motion in the flageller. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane.	3.61882e-19
CP026226.1\|AUV19165.1\|3161862_3162864_+\|dipeptide-ABC-transporter-ATP-binding-protein	gnl\|CDD\|236898	PRK11308, dppF, dipeptide transporter ATP-binding subunit; Provisional.	2.39443e-152
CP026226.1\|AUV19162.1\|3150034_3150442_-\|biopolymer-transporter-ExbD	gnl\|CDD\|376792	pfam02472, ExbD, Biopolymer transport protein ExbD/TolR. This group of proteins are membrane bound transport proteins essential for ferric ion uptake in bacteria. The Pfam family consists of ExbD, and TolR which are involved in TonB-dependent transport of various receptor bound substrates including colicins.	1.89097e-30
CP026226.1\|AUV17673.1\|3152416_3153181_-\|DUF3450-domain-containing-protein	gnl\|CDD\|378764	pfam11932, DUF3450, Protein of unknown function (DUF3450). This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are about 260 amino acids in length.	3.94907e-94
CP026226.1\|AUV17668.1\|3140302_3140587_+\|hypothetical-protein	gnl\|CDD\|373549	pfam15090, DUF4553, Domain of unknown function (DUF4553). This family of proteins is functionally uncharacterized. This family of proteins is found in vertebrates. This family includes the human protein C10orf12.	0.00151632
CP026226.1\|AUV19163.1\|3157767_3158805_+\|peptide-ABC-transporter-permease	gnl\|CDD\|226690	COG4239, COG4239, ABC-type uncharacterized transport system, permease component [General function prediction only].	5.2045e-106
CP026226.1\|AUV17676.1\|3158887_3160705_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173862	cd08497, PBP2_NikA_DppA_OppA_like_14, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	7.42873e-170
CP026226.1\|AUV17678.1\|3163493_3164945_-\|aminoacyl-histidine-dipeptidase	gnl\|CDD\|349885	cd03890, M20_pepD, M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide. Peptidase M20 family, Peptidase D (PepD, Xaa-His dipeptidase; X-His dipeptidase; aminoacylhistidine dipeptidase; dipeptidase D; Beta-alanyl-histidine dipeptidase; pepD g.p. (Escherichia coli); EC 3.4.13.3) subfamily. PepD is a cytoplasmic enzyme family characterized by its unusual specificity for the dipeptides beta-alanyl-L-histidine (L-carnosine or beta-Ala-His) and gamma-aminobutyryl histidine (L-homocarnosine or gamma-amino-butyl-His). Homocarnosine has been suggested as a precursor for the neurotransmitter gamma-aminobutyric acid (GABA), acting as a GABA reservoir, and may mediate anti-seizure effects of GABAergic therapies. It has also been reported that glucose metabolism could be influenced by L-carnosine. PepD also includes a lid domain that forms a homodimer; however, the physiological function of this extra domain remains unclear.	0
CP026226.1\|AUV17669.1\|3148135_3149371_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	7.2152e-06
CP026226.1\|AUV19164.1\|3160730_3161768_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	0
CP026226.1\|AUV17670.1\|3149382_3150018_-\|energy-transducer-TonB	gnl\|CDD\|367555	pfam03544, TonB_C, Gram-negative bacterial TonB protein C-terminal. The TonB_C domain is the well-characterized C-terminal region of the TonB receptor molecule. This protein is bound to an inner membrane-bound protein ExbB via a globular domain and has a flexible middle region that is likely to help in positioning the C-terminal domain into the iron-transporter barrel in the outer membrane. TonB_C interacts with the N-terminal TonB box of the outer membrane transporter that binds the Fe3+-siderophore complex. The barrel of the transporter, consisting of 22 beta-sheets and an inside plug, binds the iron complex in the barrel entrance.	3.01144e-16
CP026226.1\|AUV19161.1\|3144789_3147795_+\|chitinase	gnl\|CDD\|225862	COG3325, ChiA, Chitinase [Carbohydrate transport and metabolism].	2.31337e-147
CP026226.1\|AUV17682.1\|3167845_3168238_+\|Crl-family-RNA-polymerase-assembly-factor	gnl\|CDD\|369355	pfam07417, Crl, Transcriptional regulator Crl. This family contains the bacterial transcriptional regulator Crl (approximately 130 residues long). This is a transcriptional regulator of the csgA curlin subunit gene for curli fibers that are found on the surface of certain bacteria.	1.07511e-60
CP026226.1\|AUV19160.1\|3142443_3143874_+\|IS4-family-transposase-ISAeme22	gnl\|CDD\|280446	pfam02281, Dimer_Tnp_Tn5, Transposase Tn5 dimerization domain. Transposons are mobile DNA sequences capable of replication and insertion into the chromosome. Typically transposons code for the transposase enzyme, which catalyzes insertion, found between terminal inverted repeats. Tn5 has a unique method of self- regulation in which a truncated version of the transposase enzyme acts as an inhibitor. The catalytic domain of the Tn5 transposon is found in pfam01609. This domain mediates dimerization in the known structure.	4.71231e-18
CP026226.1\|AUV17672.1\|3151046_3152420_-\|MotA/TolQ/ExbB-proton-channel-family-protein	gnl\|CDD\|376576	pfam01618, MotA_ExbB, MotA/TolQ/ExbB proton channel family. This family groups together integral membrane proteins that appear to be involved translocation of proteins across a membrane. These proteins are probably proton channels. MotA is an essential component of the flageller motor that uses a proton gradient to generate rotational motion in the flageller. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane.	9.18213e-32
CP026226.1\|AUV17674.1\|3153283_3155890_-\|TonB-dependent-receptor	gnl\|CDD\|366183	pfam00593, TonB_dep_Rec, TonB dependent receptor. This model now only covers the conserved part of the barrel structure.	1.52327e-32
CP026226.1\|AUV17681.1\|3166514_3167783_+\|esterase-FrsA	gnl\|CDD\|235337	PRK05077, frsA, esterase FrsA.	0

>CP026226.1|AUV17674.1|3153283_3155890_-|TonB-dependent-receptor
MLRKSRLSAAVAFALASAAVVATPVLAEEGQNVEKLQKIKVTGSRISRVDVEGSTPVVSVTKAKIEQSGQQTVADYLKQASYNSFGGVSPASGSSFQSQSTVGLRGLGSERTLVLLNGKRVAGSPTMGGTSINLNTIPMAAVERVEVNLDGGSAIYGSDAIGGVINVVLKEGYEGLDFQGRIGSPSEEGGDEKSGSIVAGVAGEKGSLMAVYEHDKKDVIYSRDRDYLAKQGNDSPSAYGRNVEGITGLDANGDPIWKYGPLAGATNADGSCKEPFVGFEGGCNFNYGQVAATTASRSRDTLYVNGRYHINDNVDFVPQIIGSRVESFGRFAPAAGAFTIDPANPKNAQFFADNGLDAAATQGLGEAAYAYYRFSNVGPRDNYVTDTTGSMNLGFEGTIATESVGDMQWNAGYMYSKTDNKENGTGYVLKSAAQQAIADGKFVGGEFDPQSTASMAADTSRRATMDFYQWYAGVQWDMGELPAGPVSWYAGAEYNDWVYADKYDAQSEAGNIIGSAGNSSGGVRDVTAAYIESLVPITEQIELNVAGRFDKYSDFGSAFSPKASLRYQPLDNLMLRTSWSRSFRAPSLSDLYSADSESADWAKDYVYCEANGISAADCPNRQYTTTRTSNEDLKEETADTWNFGVAYSPVDDLNLSLDYYTIKIEDVIQLNSLQSLIYDELNSGSSSSITRNSQGKIGSAIAPMVNLGTLETSGLDLKVDYTYDLNYATVRYDLGGTYILKYKEGLYAGGPVIDKIGQNGLPQMRFSSGVGVNVPQWWNMDTYLSANYIDSQSQDYIADTGEEVGHIASQTTWNLNVGVEAPWNGKIQVGVKNMFNVGPSLESDGFTYDDELYSIDGRIYYLDYSQKF
>CP026226.1|AUV17673.1|3152416_3153181_-|DUF3450-domain-containing-protein
MKKALLGSLISAALLTSFNLSAATAGQAVDAQAATDNASKVSQQKIDSYAESAESALAQYKAALRQVDSLRAYNEQVGKMVDSQSAELASMQKQIAQIDQTSTEVVPLMLKMIDSLEQFVSLDLPFQKVEREDRVAALTDLMNRADVTISEKYRKILEAYQIEEGFSRTIEAYKASLDKDGDEKTYEFLRVGRIALLYQSPDGNETGMWNKKTRQWEVLPQEYRSAVEQGLRIAKKQAPPALIKLPVQTAEKAS
>CP026226.1|AUV17672.1|3151046_3152420_-|MotA/TolQ/ExbB-proton-channel-family-protein
MKGIKLAIASLIAGATLVTLPVTAAEKPVDLNALLNQVKAASTSESQLNKEREARFLADKNEQGALLAKAKADLAAEVARGEKLKATFDANDKQLTELTETLRQRSGNMGEMFGVLRQFAGEFKGIFNASARRVEHPEQTALLTRLAESKELPSSDDLTAFWTTTLSRMVDGGKVSQIPATVVYGEGNQAQKTVTQIGEFNTVSEGKYLTFVPETGKFEQLSRQPENAVLEPVAKFEQGGGSVEPIFIDPSRGVILSLLVQSPTLKERIDQGGSVGYVILALGVIGTLLALFCGARLSLIGGAMRKQLKSEQIIKGNPIGEMLGAYQDHRGDNIEDLESKLDEIILRNVPKLEKGISLIKLIASVAPLLGLLGTVVGMIATFQAITLFGTGDPKLMAGGISEALVTTMQGLVVAVPMLFLYTIVQTQSRRLIQVLEEQSAGFVARYQERLHAAKAAA
>CP026226.1|AUV17671.1|3150508_3151036_-|MotA/TolQ/ExbB-proton-channel-family-protein
MWFWLIEEVESVRRFLGLGGDVLVALFFLTLMMWALLLERWFYFMAVYPQQVKQTKTAWLARTDHLSWSARQIRRELVSRVAMAVDKGMPVIKVLIALCPLMGLLGTVVGMVQVFDTLAITGTGSPRAMASGISKATVPTMAGMIAALSGLFFVSRLDHKAKLAVQKLEDNLKHG
>CP026226.1|AUV19162.1|3150034_3150442_-|biopolymer-transporter-ExbD
MRKRHSDSGADEAAIDLTPMLDIVFIMLIFFIVTTSFVKESGVEINRPSASTAETVKKGNIMVAVRENGQVWVDKRIVEVGAVRANIERLRAENPESAVVIQADSESRSGLVVQVMDQIRMAGVQNISIAADKSS
>CP026226.1|AUV17670.1|3149382_3150018_-|energy-transducer-TonB
MRYLISLAVSCVVVFFLFLGMNKLITPDHRELTEREDVTMTDFIRLKPQETLQEKQRELPKPPPPKRPPPPPEMEVASTDRPKMDSSPMDMPKLDIPVNIGGGNALGAYSTGGGGGGMGGNNGAIPMATFEPMMPRKAALAGLASGKVLVEFTVTERGTVSNIRIVKEEPRSYDLGKAARQTIAKWTFKPAMVDGKPQASRMQQEIEFATN
>CP026226.1|AUV17669.1|3148135_3149371_-|tetratricopeptide-repeat-protein
MKKLHTLILAPVAMAVLLSTAGWAAEQPALSDRAYRAVNKAQALITEKKYGEANAKLQEALSGAGERVYDKGVILQTLGFVAAQQEKYGQATKYFADAIATGGLPPPVAQQVRYNLAQLYMAEGNFKGSINTMKEWFANLGKDEKPTPHAYITLANAHVQLKQYREAIPAVDNAIKLSAGKAPESWYLLKMAAHYELKQYKPATEVLTALVDRYPEKKKYWTQLSAMHMQAGNDAKALAALEGAYNLGMLTEANELQRLANYLAFAGIPHRAARVMEKAMKEGQIESTAANYKTLANYWHQAKELDPAIDTLAKSYKLAPNAELQLKMARMMIQSKRYQDLVAFAAKPAANASGEQRADLKFLTGVAYFEQQKPKEALSAFTQAAQNGNVSGRASPWISFLKEQQGGAVTQ
>CP026226.1|AUV19161.1|3144789_3147795_+|chitinase
MLVALAAVPAWAQAAYPAYQAGTAYKAGDIVSNAGALYECKEFPYSGWCGASPYHYAPGVGTVWADAWKLYGGEVPPPSLVVAIGSPAVGASVSEGASVALAVTLSGPVTALARVEYLIDGTLVATATASPWSASWSAAGAGNHALKARALDKDGKVLSEADSSFKVAAVVAPEAPRVSIASPAAGARVTLGRALTVSGNVTDANDDVAKVELFVNGQKVGEDTSAPWQLSWTPQNKGLTGLKLVATDKTNLSGESAQVDVQVEEAALPPTGGNLSCDVRQIYRADGSECMGDDHGRRVIGYFTSWRTGKNGLPAYLVSDIPWDKITHINYAFAAVDEQSHTIKVDDAATKLTWNGVPGAEMDPEFAYQGHFNLLSKYKKQYPDVKTLISVGGWADTRGFYAATTKGDCSVNTAGINAFADSAVGFIRQYGFDGVDIDYEYPTSMKDAGNPNDFPLSNQCRGKLFANYEVLMKTLRNKLDSAGTEDGRKYMLTIASPASAYLLRGMENFQVTQYLDYVNLMTYDFHGAWNHFVGHNAALFDNKADPELSQWGVYTQAQFGGIGYLNSAWAAHYFRGALAAGKINIGVPYYTRGWQGVSGGTHGLGGKAALPSQSDCQPGTGGSTIPCGNGAVGIDNIWHDLDKNGKEIGGGAVPMWHAKNLEHAASLGITTLPSYGQAWGLDPNNPAHVMQGQYVRYYDDKAHAPWLWNEQKKVFLSTEDEESMGHKLDYIVKRGLGGVMFWEMAGDYDFDAAKNEYVMGSTLTSLAYEKFSKADKAALKQNDLPAPAAQLDIGVSLSGFKEGDSNYPINPTLKLTNKSTQTIPGGTRIEFLVPTSTSDTITDQSGMGLKVVESGGNQNSDGIANEKDFHKVALTLPVWKAWTPGTDVEVAMTYYLPAAGVPSGMRLIAGSQTIGLKSDFPALAEAVLGSSGGGDGGSGGTTCASQNVNPADYNAYPTWPRGDHANGNDRMTHNKRVWQANWWTSSEPKAGDGSWKLICSY
>CP026226.1|AUV19160.1|3142443_3143874_+|IS4-family-transposase-ISAeme22
MITSALHRAADWAKSVFSSAALGDPRRTTRLVNVAAQLAKCSGKSITISSEGCEAMQEGAYRFIRNPNVSAEAIRKAGAMQTVKLAQAFPELLAIEDTTSLSYRHQVAEELGKLGAIGDKSRGWWVHSVLLLEATTFRTVGLLHQEWWMRPDDPADADEKESGKWLAAAATSRLRMGSMMSNVIAVCDREADIHAYLQDKLTHKERFVVRSKHPRKDTGSGLYLYDHLKNQPELGGYQISIPQKGVVDKRGKRKNRPARKASLSLRSGRITLKQGNITLNAVLAEEINPPKGETPLKWLLLTSEPVESLAQALRVIDIYTHRWRIEEFHKAWKTGAGAERQRMEEPDNLERMVSILSFVAVRLLQLRESFTLPQALRAQGLLKEAEHVESQSAETVLTQDECQLLGYLDKGKRKRKEKAGSLQWAYMAIARLGGFMDSKRTGIASWGALWEGWEALQSKLDGFLAAKDLMAQGIKI
>CP026226.1|AUV17668.1|3140302_3140587_+|hypothetical-protein
MQPWPRRGLRDAILCRVAVGSFGNLRDTLSGPWSQHRVSPSAGCQPPGKGAEWGNKVFINPMMWPFAFVFQMAMAQKKPAIIAGFAPGIEDAAS
>CP026226.1|AUV19163.1|3157767_3158805_+|peptide-ABC-transporter-permease
MNPVTLKKLKRFKSIKRGYYSFVIFSVLVVISLLAELLVNSRALAVSYQGDLYFPTYGDVIPGQHFGLDYEYETNYRQLKSQFAKEGKGDWVLLPLVPWNPYEQDFKEEAYPPYAPSLAERHFLGTDTSGRDVLARLVYGFRIAIGFAFIALVASYVIGVSIGCMMGFLGGRFDLLMQRFIEIWSQVPFLYVIMILVSLAKPNFGLFVGINVLFGWMGITWYMRTLTYKERARDYVMAARAQGASTRRIIFNHILPNTLMMIVTLAPFAVVGNISTLTALDYLGFGLAPPTPSWGELLSQGINNLDAIWIVSSVVAAVSLVLIMVSFIGEAIREAFDPRKFTRYQ
>CP026226.1|AUV17676.1|3158887_3160705_+|ABC-transporter-substrate-binding-protein
MNNKIKWTGALFLLLNGSWVWAASLPADLTWETNDTDPVFASPKALPGGNLNLFVDSFPLTFRTVGPDSNGSFRSFILDNQMRLISFHPNTGNPIPALANAWAIAPDSQTVYFRLDPRAKWSDGKPVTADDYTFGYEMMRSKDIKGPWFNNYYTTEVVAVEKIDDHTILVKAGSRKAKLDLLNTTELWPQPKHYYKMGPNWVKQYNWAVVPTTGPYVMSDVKKGKSVTFSKQKEWWAKDDRYNQHRFNLDTIKVQVIRDHNIAFRHFLKGELDTFEMILPNWWHEKAVTPEYKQGYVQKVMAMTDTKQGGQGVHLNVANPKLADLNVRLGIQHAFNIDKMIETVLHGDYDRATTFGSGFGAFTDIALPERAYDIAKAREYFAKGGYGKQGPDGILQNDRGERLTLALTYTSQEHSKRLTVLKEEAKKAGLDLELNLVDGATGFKVMLEKKHEAAWLGWGGGGLYPQYWESFHSDNANKPQTNNLFNVADKELDSLIDAYNVEFDMDKRAALSHQIQQRIYDLAIFVPGVQLNYVRASSWRYVMLPEVPATRNTPDLLYWPMDGYPHSSGGLLWIDPKVKEETQKAKSDGKALAPITLIDKTYAHH
>CP026226.1|AUV19164.1|3160730_3161768_+|ABC-transporter-ATP-binding-protein
MPNTQATAPGTRDHEGQSLSPILEVRDLEVEFAVDDGKIKVLDGVSFQVAPGKTLGIVGESGCGKSVTSLAIMGLLPRPHGQVVGGSIRFQGEELLNLPPEQMYKVRGNRISMIFQEPMTALNPVQTVGDQLMEVFRLHRPDYSKAQRRDAAIAMLKKVGIPEPAQRFAAYPHNLSGGMRQRVMIAMALACEPALLICDEPTTALDVTIQAQILDLMKELQAQTGMAIIFITHDLGVVAELCDEVVVMYAGRAVERADIYELFDHPRHPYTHGLMASIPRLEDVPKSLLKTIKGQVPALHEMPAGCRFSNRCPHATPLCVETIPVTEQLSERHGVACHHWKEVSL
>CP026226.1|AUV19165.1|3161862_3162864_+|dipeptide-ABC-transporter-ATP-binding-protein
MTSLLSVSNLKQHFKMGGGFLRKQYTVYAVDGISFDLRQGETLGLVGESGCGKSTLGRSLLKLFEPSAGSITFEGRDITHLSPKEMRSLRQEMQIVFQDPAESLNSRHTVGQILEEPFIIHGKGNAEQRRTWVQELLEKVGLPGSAVDRYPHEFSGGQRQRIGIARAIALKPKLLVCDEAVSALDVSVQSQIVNLLLNLQREMNLAIIFIAHDLSVVKHISDRIAVMYLGRIVELAEAQALYLAPRHPYTQALISAIPVPDPRRRSQRILLTGDVPSPISPPSGCHFHQRCPHATDLCRTRSPALEACGGQGHQVACHFPLTVQEAVPLGKAI
>CP026226.1|AUV17677.1|3163109_3163229_-|hypothetical-protein
MFENLAVLFHLKGATSKKGAEEKDTYAPATRNYYFRYGA
>CP026226.1|AUV17678.1|3163493_3164945_-|aminoacyl-histidine-dipeptidase
MAQLSSLSPKLIWQFFEQICSIPHPSKHEAQLSAWIVAWAQGEGLAVKQDAVGNIIIKKPATPGMENRKAVVLQAHIDMVPQANADTQHDFTTDPIDAYIDGEWVTARGTTLGADNGMGMAGCLAVLADKTIKHGPLEVLLTTDEETGMTGAFGLEAGWLEGEILLNTDSEEDGEVYMGCAGGVDANIRFPLELVAATEGEGFELQVKGLRGGHSGVDIHRGRGNANKLLVRLLKAAEPLGVRLGDLSGGTLRNAIPREARASLLVPAASVADFKALVDRYAGIYQSELAATEANLTVLLTAREKPAQLMSESLQSRLLDALMACPNGVMRMSDAIPGVTETSTNLGVIKTLEGEVYVQCLIRSLIDSGRENIEQMTRSLFTLAGASCEFTGAYPGWAPNVDSPVMALVRNSYQTLFGEMPNVMVIHAGLECGLFKSAYPDWDMVSFGPTIRGAHAPGEKVHIPAVERFWHLLVHVLEHIPAK
>CP026226.1|AUV17679.1|3165314_3165428_+|hypothetical-protein
MLSNQEFMMSGSNSTYWFAQSLYTQGFNYPNPYATRR
>CP026226.1|AUV17680.1|3165872_3166340_+|xanthine-phosphoribosyltransferase
MPKKFYVSWDNLQREARRLARRQLPVSQWKGIIAVSRGGLVPAALMARELGIRNVETLCISSYDHDNQRELAVVKAATTAGDGEGWLVVDDLVDTGGTAKAIRELYPRAKFITIFAKPMGEPLVDDFEVAIPQDTWIEQPWDMALEFAKPICDEA
>CP026226.1|AUV17681.1|3166514_3167783_+|esterase-FrsA
MEPNDDTNLTEKLFTRVKKVLETSEVSNSSPVDEQDSALSDSFIDGALSPRWYRLLRRPTWAWQGADPVEVEQTLAHIAMGQGERSHERYLDTIKGYVPGNWVYEWSQLAGRYFNTGRTLLGEGDRAAALKSLLKAVRYYSIASYPHLKHDELADQAQLLGNMAYREAGRLFKVPLKELQVPFRGKTIQGYLHLPTTEKPVPLVIVSGGIDSLQVDFLNFYFKCLEPHGIGMLSLDMPGTGYAEHWPLVQDTSRLHQAVLNYLSEVAWVDHQRIAMVGFRLAGNVAARLAFVEPFKLRTVVCIGAGINQVFTNQEMFARCPRMMRDGLANRLGADAAQWDLLRTKCQVFSLKTQGLLGSRTSVPILSIGHKKDFICPEQDVRALAAASRNGKAVVFDKQPLLEVYDEALKETVDWLKKHLCT
>CP026226.1|AUV17682.1|3167845_3168238_+|Crl-family-RNA-polymerase-assembly-factor
MSERVTYKRLLRQFAAIGPYLREDLCEEGRYRFDCLSVCVSAKPAPDKREFWGWWLVLEQADHSFSYHYQTGFYNADGEWIDKALPKKHQAEVERTLQHFYKLISGKLTQLECTLSPAKQVTAELSVTAA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

70400 : 78055

Mycoplasma_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV15266.1\|70400_71684_-	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	3.3e-30	37.4
AUV15267.1\|71680_72982_-	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	2.9e-34	41.9
AUV15268.1\|73139_73478_-	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
AUV15269.1\|73479_75327_-	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	2.2e-104	42.0
AUV15270.1\|76063_76387_-	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	1.2e-21	43.9
AUV15271.1\|76402_76786_-	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	2.8e-54	79.0
AUV15272.1\|76840_78055_-	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	3.0e-33	30.3

DBSCAN-SWA_2

340975 : 445305

Enterobacteria_phage(20.83%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV18978.1\|340975_342179_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	1.2e-114	70.5
AUV18979.1\|342381_342918_-	hypothetical protein	NA	NA	NA	NA
AUV15456.1\|342942_344262_-	HlyC/CorC family transporter	NA	NA	NA	NA
AUV15457.1\|344503_345214_-	phosphate transport system regulatory protein PhoU	NA	NA	NA	NA
AUV15458.1\|345393_346212_-	phosphate ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	2.8e-14	27.8
AUV15459.1\|346316_347966_-	phosphate ABC transporter, permease protein PstA	NA	NA	NA	NA
AUV15460.1\|347983_350221_-	phosphate ABC transporter permease	NA	NA	NA	NA
AUV15461.1\|350389_350938_-\|tRNA	tRNA adenosine(34) deaminase TadA	NA	NA	NA	NA
AUV15462.1\|351434_351659_-	hypothetical protein	NA	NA	NA	NA
AUV15463.1\|352490_354098_+	malate synthase A	NA	NA	NA	NA
AUV15464.1\|354167_355481_+	isocitrate lyase	NA	NA	NA	NA
AUV15465.1\|355906_356650_-	DnaA inactivator Hda	NA	NA	NA	NA
AUV15466.1\|356710_357739_-	DUF2066 domain-containing protein	NA	NA	NA	NA
AUV15467.1\|357880_358507_-	uracil phosphoribosyltransferase	NA	NA	NA	NA
AUV15468.1\|358682_359720_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.2e-76	47.1
AUV18980.1\|359740_360388_+	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	6.8e-24	37.8
AUV15469.1\|360502_361264_-	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
AUV15470.1\|361371_362706_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
AUV18981.1\|363915_365334_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
AUV15471.1\|365573_366413_-	DUF2726 domain-containing protein	NA	NA	NA	NA
AUV15472.1\|366671_367184_+	ACT domain-containing protein	NA	NA	NA	NA
AUV15473.1\|367260_369330_+	polyphosphate kinase 1	NA	NA	NA	NA
AUV15474.1\|369319_370810_+	exopolyphosphatase	NA	NA	NA	NA
AUV15475.1\|371086_372313_-\|transposase	transposase	O80301	Enterobacteria_phage	7.7e-154	78.6
AUV15476.1\|372370_372775_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	6.7e-30	54.8
AUV15477.1\|372694_374011_-	magnesium transporter	NA	NA	NA	NA
AUV15478.1\|374356_375496_-\|transposase	transposase	A0A077SLN2	Escherichia_phage	7.2e-146	68.7
AUV15479.1\|375893_376844_+\|transposase	IS1595-like element ISKpn3 family transposase	NA	NA	NA	NA
AUV15480.1\|377258_378467_-	flagellar hook-associated protein 3	NA	NA	NA	NA
AUV15481.1\|378470_380468_-	flagellar hook-associated protein FlgK	NA	NA	NA	NA
AUV15482.1\|380471_381572_-	flagellar assembly peptidoglycan hydrolase FlgJ	A0A0A7RU71	Clostridium_phage	4.4e-15	36.5
AUV15483.1\|381618_382716_-	flagellar basal body P-ring protein FlgI	NA	NA	NA	NA
AUV15484.1\|382776_383448_-	flagellar basal body L-ring protein FlgH	NA	NA	NA	NA
AUV15485.1\|383464_384253_-	flagellar basal-body rod protein FlgG	NA	NA	NA	NA
AUV15486.1\|384267_385014_-	flagellar basal-body rod protein FlgF	NA	NA	NA	NA
AUV15487.1\|385160_386507_-	flagellar hook protein FlgE	NA	NA	NA	NA
AUV15488.1\|387338_387758_-	flagellar basal body rod protein FlgC	NA	NA	NA	NA
AUV15489.1\|387754_388156_-	flagellar basal body rod protein FlgB	NA	NA	NA	NA
AUV15490.1\|388217_389042_-	chemotaxis protein CheR	NA	NA	NA	NA
AUV15491.1\|389059_389971_-	chemotaxis protein CheV	Q56AR1	Bacillus_thuringiensis_phage	1.3e-36	32.8
AUV15492.1\|390130_390814_+	flagella basal body P-ring formation protein FlgA	NA	NA	NA	NA
AUV15493.1\|390908_391229_+	flagellar biosynthesis anti-sigma factor FlgM	NA	NA	NA	NA
AUV18982.1\|391228_391642_+	flagellar protein FlgN	NA	NA	NA	NA
AUV15494.1\|391685_392228_-	phosphodiesterase	NA	NA	NA	NA
AUV15495.1\|392291_393518_-\|transposase	transposase	O80301	Enterobacteria_phage	7.7e-154	78.6
AUV15496.1\|393575_393980_+\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	6.7e-30	54.8
AUV15497.1\|394033_395674_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
AUV15498.1\|395963_396866_+	EamA/RhaT family transporter	NA	NA	NA	NA
AUV15499.1\|396967_397660_-	16S rRNA pseudouridine(516) synthase RsuA	NA	NA	NA	NA
AUV15500.1\|397832_399023_+	HD domain-containing protein	NA	NA	NA	NA
AUV15501.1\|399232_400459_-\|transposase	transposase	O80301	Enterobacteria_phage	7.7e-154	78.6
AUV15502.1\|400516_400921_+\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	6.7e-30	54.8
AUV15503.1\|401184_402078_+	EamA family transporter	NA	NA	NA	NA
AUV15504.1\|402168_404019_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AUV15505.1\|404087_404381_+	hypothetical protein	NA	NA	NA	NA
AUV15506.1\|404306_405320_-\|transposase	IS110 family transposase ISAeca3	NA	NA	NA	NA
AUV15507.1\|405448_405841_-	DUF2750 domain-containing protein	NA	NA	NA	NA
AUV15508.1\|405935_406484_-	hypothetical protein	NA	NA	NA	NA
AUV15509.1\|406730_406979_+	TIGR02647 family protein	NA	NA	NA	NA
AUV15510.1\|406965_407277_-	hypothetical protein	NA	NA	NA	NA
AUV15511.1\|407354_407564_-	cold-shock protein	A0A1W6JNX5	Morganella_phage	2.8e-16	61.4
AUV15512.1\|407770_408871_-	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
AUV15513.1\|408965_409952_-	alpha-ketoacid dehydrogenase subunit beta	A0A0K0KW14	Prochlorococcus_phage	3.0e-07	28.8
AUV15514.1\|409948_411037_-	pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha	NA	NA	NA	NA
AUV15515.1\|411308_412328_-	succinylglutamate desuccinylase	NA	NA	NA	NA
AUV15516.1\|412597_412807_-	DUF1127 domain-containing protein	NA	NA	NA	NA
AUV15517.1\|413337_414231_+	DNA replication protein	NA	NA	NA	NA
AUV15518.1\|414312_418149_-	ATP-dependent helicase	A0A160DHD3	Gordonia_phage	1.7e-45	29.4
AUV15519.1\|418367_419021_-	DUF480 domain-containing protein	NA	NA	NA	NA
AUV15520.1\|419284_421003_-	ligase	NA	NA	NA	NA
AUV18983.1\|421090_423142_-	YjbH domain-containing protein	NA	NA	NA	NA
AUV15521.1\|423171_423927_-	hypothetical protein	NA	NA	NA	NA
AUV18984.1\|423923_424613_-	YjbF family lipoprotein	NA	NA	NA	NA
AUV15522.1\|424664_424892_-	hypothetical protein	NA	NA	NA	NA
AUV15523.1\|425042_427220_-	tyrosine-protein kinase	NA	NA	NA	NA
AUV15524.1\|427275_427704_-	protein tyrosine phosphatase	NA	NA	NA	NA
AUV15525.1\|427767_428883_-	polysaccharide export protein Wza	NA	NA	NA	NA
AUV15526.1\|428942_429974_-\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
AUV15527.1\|430477_431599_-	glycosyl transferase	NA	NA	NA	NA
AUV15528.1\|431667_432753_-	glycosyl transferase	NA	NA	NA	NA
AUV15529.1\|432759_433563_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
AUV15530.1\|433559_434495_-	rhamnosyl transferase	NA	NA	NA	NA
AUV15531.1\|434467_434785_-	hypothetical protein	Q9AYY5	Salmonella_phage	5.1e-17	45.6
AUV15532.1\|434769_435684_-	hypothetical protein	Q9AYY5	Salmonella_phage	8.3e-36	35.3
AUV15533.1\|435760_436999_-	hypothetical protein	NA	NA	NA	NA
AUV18985.1\|436995_437553_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	5.1e-52	57.5
AUV15534.1\|437614_438493_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.1e-104	63.1
AUV15535.1\|438607_439495_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	8.1e-28	34.7
AUV15536.1\|439494_440580_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.6e-97	51.2
AUV15537.1\|441436_442858_+\|transposase	IS66 family transposase ISKpn15	NA	NA	NA	NA
AUV15538.1\|442840_443158_-	hypothetical protein	NA	NA	NA	NA
AUV15539.1\|443419_444337_-\|transposase	IS5/IS1182 family transposase	A0A1V0E8E1	Vibrio_phage	4.1e-99	58.6
AUV15540.1\|444366_445305_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	8.3e-39	35.6

DBSCAN-SWA_3

456324 : 463714

Enterobacteria_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV15545.1\|456324_457641_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.4e-14	28.1
AUV15546.1\|457630_458449_-	ABC transporter permease	NA	NA	NA	NA
AUV18987.1\|458532_459075_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.1e-54	60.9
AUV15547.1\|459136_460015_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.1e-104	63.1
AUV15548.1\|460129_461017_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	8.1e-28	34.7
AUV15549.1\|461016_462102_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	3.5e-97	50.6
AUV15550.1\|463006_463714_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	1.9e-27	34.1

DBSCAN-SWA_4

483255 : 543700

Acinetobacter_phage(22.22%)

integrase,transposase

attL 477940:477957|attR 484717:484734

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
477940:477957	attL	NA	NA	NA	NA
AUV15564.1\|483255_484560_-\|integrase	integrase	A0A077KET4	Ralstonia_phage	2.1e-16	25.3
AUV15565.1\|484686_484914_+	hypothetical protein	NA	NA	NA	NA
484717:484734	attR	NA	NA	NA	NA
AUV15566.1\|485002_485998_-	sulfate ABC transporter substrate-binding protein	NA	NA	NA	NA
AUV15567.1\|486327_487743_-	multidrug transporter	NA	NA	NA	NA
AUV15568.1\|492236_492872_+	TetR family transcriptional regulator	NA	NA	NA	NA
AUV18990.1\|493043_493526_+	methyltransferase domain-containing protein	NA	NA	NA	NA
AUV15569.1\|493694_494870_+	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
AUV15570.1\|494933_495797_-	acyl-CoA thioesterase II	NA	NA	NA	NA
AUV15571.1\|495978_496350_-	endonuclease domain-containing protein	NA	NA	NA	NA
AUV15572.1\|496563_497487_-	23S rRNA pseudouridine(2605) synthase RluB	NA	NA	NA	NA
AUV15573.1\|497479_498172_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.7e-20	36.3
AUV15574.1\|498213_499116_-	segregation/condensation protein A	NA	NA	NA	NA
AUV15575.1\|499087_499708_-	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
AUV15576.1\|499832_500714_-	PHP domain-containing protein	NA	NA	NA	NA
AUV15577.1\|501138_502773_+	anthranilate synthase component 1	NA	NA	NA	NA
AUV15578.1\|502765_503365_+	type 1 glutamine amidotransferase	A0A0P0IKJ1	Acinetobacter_phage	3.5e-27	36.3
AUV15579.1\|503375_504389_+	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	3.4e-54	38.7
AUV18991.1\|504508_505894_+	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase	NA	NA	NA	NA
AUV15580.1\|505970_507164_+	tryptophan synthase subunit beta	NA	NA	NA	NA
AUV15581.1\|507160_507967_+	tryptophan synthase subunit alpha	NA	NA	NA	NA
AUV15582.1\|508356_509307_-\|transposase	IS1595-like element ISKpn3 family transposase	NA	NA	NA	NA
AUV15583.1\|509401_510931_-	flagellin	NA	NA	NA	NA
AUV15584.1\|511244_511541_+	XRE family transcriptional regulator	NA	NA	NA	NA
AUV15585.1\|511524_512841_+	phosphatidylinositol kinase	NA	NA	NA	NA
AUV15586.1\|512939_513182_+	DUF3297 domain-containing protein	NA	NA	NA	NA
AUV15587.1\|513178_513358_-	hypothetical protein	NA	NA	NA	NA
AUV15588.1\|513454_513889_-	hypothetical protein	NA	NA	NA	NA
AUV15589.1\|513899_514388_-	hypothetical protein	NA	NA	NA	NA
AUV15590.1\|514488_515382_+	LysR family transcriptional regulator	NA	NA	NA	NA
AUV15591.1\|515532_516636_+	YdcF family protein	NA	NA	NA	NA
AUV15592.1\|516924_517899_+	taurine ABC transporter substrate-binding protein	NA	NA	NA	NA
AUV15593.1\|517915_518683_+	taurine transporter ATP-binding subunit	G9BWD6	Planktothrix_phage	1.2e-22	36.4
AUV15594.1\|518679_519510_+	taurine transporter subunit	NA	NA	NA	NA
AUV15595.1\|519589_520441_+	taurine dioxygenase	NA	NA	NA	NA
AUV15596.1\|520582_521920_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
AUV15597.1\|522024_522393_-	DUF1428 domain-containing protein	NA	NA	NA	NA
AUV15598.1\|522476_523838_-	MFS transporter	NA	NA	NA	NA
AUV15599.1\|524002_524896_-	protoheme IX farnesyltransferase	NA	NA	NA	NA
AUV15600.1\|524904_525234_-	cytochrome o ubiquinol oxidase subunit IV	NA	NA	NA	NA
AUV15601.1\|525234_525930_-	cytochrome o ubiquinol oxidase subunit III	NA	NA	NA	NA
AUV15602.1\|525850_527827_-	cytochrome o ubiquinol oxidase subunit I	NA	NA	NA	NA
AUV15603.1\|527830_528919_-	cytochrome o ubiquinol oxidase subunit II	NA	NA	NA	NA
AUV15604.1\|529842_530751_+	LysR family transcriptional regulator	NA	NA	NA	NA
AUV18992.1\|530841_531156_-	DUF3634 domain-containing protein	NA	NA	NA	NA
AUV15605.1\|531266_532253_-	nucleoside hydrolase	NA	NA	NA	NA
AUV15606.1\|532287_533514_-\|transposase	transposase	O80301	Enterobacteria_phage	7.7e-154	78.6
AUV15607.1\|533571_533976_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	3.3e-29	54.0
AUV15608.1\|534167_534467_-	DUF3861 domain-containing protein	NA	NA	NA	NA
AUV15609.1\|534548_534971_+	MarR family transcriptional regulator	NA	NA	NA	NA
AUV15610.1\|535100_535670_+	hypothetical protein	NA	NA	NA	NA
AUV15611.1\|535666_535870_-	hypothetical protein	NA	NA	NA	NA
AUV15612.1\|536051_536492_-	azurin	NA	NA	NA	NA
AUV15613.1\|536791_537835_+	FAD:protein FMN transferase ApbE	NA	NA	NA	NA
AUV15614.1\|537876_538302_-	Hsp20/alpha crystallin family protein	A0A1B2LRT2	Wolbachia_phage	1.0e-12	40.0
AUV15615.1\|538572_540219_+	hypothetical protein	NA	NA	NA	NA
AUV15616.1\|540279_541242_+	potassium transporter Kef	NA	NA	NA	NA
AUV15617.1\|541494_542301_+	exodeoxyribonuclease III	A0A0N9QXX6	Chrysochromulina_ericina_virus	2.8e-11	26.4
AUV15618.1\|542362_543700_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

1274238 : 1284207

uncultured_Mediterranean_phage(25.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV16208.1\|1274238_1276104_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-34	32.6
AUV16209.1\|1276317_1278105_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.2e-73	41.1
AUV16210.1\|1278194_1278638_-	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	1.3e-26	47.9
AUV16211.1\|1278653_1278869_-	30S ribosomal protein S21	NA	NA	NA	NA
AUV16212.1\|1279048_1280062_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	2.0e-107	58.0
AUV16213.1\|1280135_1281119_-	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	3.8e-34	33.7
AUV16214.1\|1281165_1282236_-	LysM peptidoglycan-binding domain-containing protein	I2E8W3	Clostridium_phage	1.7e-11	34.9
AUV19033.1\|1282245_1282821_-	DedA family protein	NA	NA	NA	NA
AUV16215.1\|1282823_1283441_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	5.3e-34	45.4
AUV16216.1\|1283445_1284207_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	4.8e-69	52.6

DBSCAN-SWA_6

1486625 : 1504412

Liberibacter_phage(25.0%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV16386.1\|1486625_1487393_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AUV16387.1\|1488253_1489867_+\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
AUV16388.1\|1490295_1491327_-\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
AUV16389.1\|1492101_1494090_+	SAM-dependent DNA methyltransferase	A0A220A2U5	Liberibacter_phage	7.4e-29	25.8
AUV16390.1\|1495063_1496080_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.9e-186	99.4
AUV19057.1\|1496117_1496243_-	sugar kinase	Q6QLL3	Human_immunodeficiency_virus	5.1e-13	100.0
AUV16391.1\|1496179_1496686_+	hypothetical protein	NA	NA	NA	NA
AUV16392.1\|1496701_1497733_-\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
AUV16393.1\|1497860_1498361_+	DUF1643 domain-containing protein	A0A142F2K6	Mycobacterium_phage	2.0e-31	50.0
AUV16394.1\|1498389_1501569_+	type I restriction endonuclease subunit R	NA	NA	NA	NA
AUV16395.1\|1501565_1501850_+	hypothetical protein	NA	NA	NA	NA
AUV16396.1\|1501849_1502074_+	hypothetical protein	NA	NA	NA	NA
AUV19058.1\|1502180_1503191_+	hypothetical protein	NA	NA	NA	NA
AUV16397.1\|1503090_1503357_-	hypothetical protein	NA	NA	NA	NA
AUV16398.1\|1503380_1504412_+\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_7

1507566 : 1565691

Klosneuvirus(20.0%)

integrase,transposase,protease,tRNA

attL 1520684:1520700|attR 1525519:1525535

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV16401.1\|1507566_1508508_+\|transposase	IS481 family transposase	E9P643	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	4.0e-65	41.9
AUV16402.1\|1508619_1510302_+\|transposase	transposase	NA	NA	NA	NA
AUV16403.1\|1510304_1511213_+\|transposase	transposase	NA	NA	NA	NA
AUV16404.1\|1511209_1512427_+\|transposase	transposase	NA	NA	NA	NA
AUV16405.1\|1512487_1513102_+	recombinase family protein	A0A0C4UR34	Shigella_phage	1.3e-37	51.9
AUV16406.1\|1513154_1513391_-	mercury resistance protein	NA	NA	NA	NA
AUV16407.1\|1513387_1513753_-	mercuric resistance transcriptional repressor protein MerD	NA	NA	NA	NA
AUV16408.1\|1513769_1515416_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-39	28.3
AUV16409.1\|1515412_1515658_-	hypothetical protein	NA	NA	NA	NA
AUV16410.1\|1515660_1515936_-	mercuric transporter periplasmic component	NA	NA	NA	NA
AUV16411.1\|1515951_1516302_-	mercuric ion transporter MerT	NA	NA	NA	NA
AUV16412.1\|1516373_1516808_+	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
AUV16413.1\|1516835_1517162_-	hypothetical protein	NA	NA	NA	NA
AUV16414.1\|1517180_1517360_+	hypothetical protein	NA	NA	NA	NA
AUV16415.1\|1517289_1518129_-	sulfonamide-resistant dihydropteroate synthase Sul1	NA	NA	NA	NA
AUV16416.1\|1518122_1518470_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
AUV19059.1\|1518633_1519425_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA1	NA	NA	NA	NA
AUV16417.1\|1519570_1520584_+\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
AUV16418.1\|1520522_1520795_+\|transposase	transposase	NA	NA	NA	NA
1520684:1520700	attL	NA	NA	NA	NA
AUV16419.1\|1521085_1522111_-	hypothetical protein	NA	NA	NA	NA
AUV16420.1\|1522209_1523229_-\|integrase	site-specific integrase	K7PHM9	Enterobacterial_phage	4.1e-15	25.2
AUV16421.1\|1523447_1524083_+	RDD family protein	NA	NA	NA	NA
AUV16422.1\|1524227_1525298_-	LPS export ABC transporter permease LptG	NA	NA	NA	NA
AUV19060.1\|1525323_1526430_-	LPS export ABC transporter permease LptF	NA	NA	NA	NA
1525519:1525535	attR	NA	NA	NA	NA
AUV16423.1\|1526608_1528120_+	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	1.4e-48	37.6
AUV16424.1\|1528289_1528745_+	DNA polymerase III subunit chi	NA	NA	NA	NA
AUV16425.1\|1528747_1531663_+\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	1.9e-137	36.0
AUV16426.1\|1531870_1533163_+	HlyC/CorC family transporter	NA	NA	NA	NA
AUV16427.1\|1533181_1533847_+	DedA family protein	NA	NA	NA	NA
AUV16428.1\|1533983_1534811_+	D-alanyl-D-alanine endopeptidase	NA	NA	NA	NA
AUV16429.1\|1536007_1536196_-	carbon storage regulator	A0A2I7RT00	Vibrio_phage	5.0e-12	66.7
AUV16430.1\|1536289_1537537_-	aspartate kinase	NA	NA	NA	NA
AUV16431.1\|1537553_1540178_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.8e-75	37.5
AUV16432.1\|1540457_1540964_-	RecX family transcriptional regulator	NA	NA	NA	NA
AUV16433.1\|1541005_1542070_-	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	1.2e-115	64.4
AUV19061.1\|1542150_1542642_-	damage-inducible protein CinA	B5TK85	Pseudomonas_phage	9.0e-29	49.0
AUV16434.1\|1542841_1543249_+	hypothetical protein	NA	NA	NA	NA
AUV16435.1\|1543512_1546083_+	DNA mismatch repair protein MutS	A0A1V0SJ67	Klosneuvirus	2.2e-33	24.9
AUV16436.1\|1546153_1547752_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	1.2e-26	25.7
AUV16437.1\|1547761_1548289_-	hypothetical protein	NA	NA	NA	NA
AUV16438.1\|1548452_1548932_+	MarR family transcriptional regulator	NA	NA	NA	NA
AUV16439.1\|1550655_1551366_-	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
AUV16440.1\|1551489_1551861_+	dihydroneopterin aldolase	NA	NA	NA	NA
AUV16441.1\|1551860_1552370_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
AUV16442.1\|1552487_1552970_+	DNA-binding protein	NA	NA	NA	NA
AUV16443.1\|1554428_1555547_-	GTP-binding protein	NA	NA	NA	NA
AUV16444.1\|1555627_1557034_-	FAD-binding protein	NA	NA	NA	NA
AUV16445.1\|1557149_1557767_-	amino acid transporter	NA	NA	NA	NA
AUV16446.1\|1557843_1558761_+	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	1.4e-14	25.3
AUV16447.1\|1558757_1560329_-	diguanylate phosphodiesterase	NA	NA	NA	NA
AUV16448.1\|1560560_1563158_-	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	NA	NA	NA	NA
AUV16449.1\|1563387_1565691_-\|protease	serine protease	A0A2H4T2U1	Tomelloso_virus	2.3e-05	23.6

DBSCAN-SWA_8

1889760 : 1968483

Bacillus_phage(18.75%)

transposase,integrase,tRNA

attL 1950283:1950299|attR 1961770:1961786

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV16745.1\|1889760_1890147_-\|tRNA	tRNA-binding protein	NA	NA	NA	NA
AUV16746.1\|1890161_1891607_-	amino acid permease	NA	NA	NA	NA
AUV16747.1\|1891708_1892164_-	beta-galactosidase subunit beta	NA	NA	NA	NA
AUV16748.1\|1892160_1895247_-	beta-galactosidase subunit alpha	L0N6M2	Herpes_simplex_virus	1.0e-157	34.7
AUV16749.1\|1895568_1896534_-	transcriptional regulator EbgR	C6ZCU4	Enterobacteria_phage	1.6e-16	25.2
AUV19074.1\|1902671_1903211_+	gamma carbonic anhydrase family protein	NA	NA	NA	NA
AUV16750.1\|1903291_1906045_-	DNA polymerase I	A0A218MKQ4	uncultured_virus	1.4e-73	33.0
AUV16751.1\|1906446_1907097_+	isoprenoid biosynthesis protein ElbB	NA	NA	NA	NA
AUV16752.1\|1907169_1907601_-	cell division protein ZapB	NA	NA	NA	NA
AUV16753.1\|1907600_1908881_-	hypothetical protein	NA	NA	NA	NA
AUV16754.1\|1908902_1909682_-	serine O-acetyltransferase	NA	NA	NA	NA
AUV16755.1\|1909690_1910602_-	divalent metal cation transporter FieF	NA	NA	NA	NA
AUV16756.1\|1910689_1911382_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	1.7e-33	38.4
AUV16757.1\|1911378_1912734_+	HAMP domain-containing protein	W8CYF6	Bacillus_phage	1.3e-16	26.0
AUV16758.1\|1912804_1913269_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
AUV19075.1\|1913300_1914671_-	MATE family efflux transporter	NA	NA	NA	NA
AUV16759.1\|1914685_1915312_-	SCO family protein	NA	NA	NA	NA
AUV16760.1\|1915502_1915793_-	hypothetical protein	NA	NA	NA	NA
AUV16761.1\|1916143_1916770_-	repressor LexA	A0A1W6JNS2	Morganella_phage	6.4e-11	35.7
AUV16762.1\|1916974_1919398_+	glycerol-3-phosphate 1-O-acyltransferase	NA	NA	NA	NA
AUV16763.1\|1919515_1920853_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
AUV16764.1\|1920903_1921767_-	4-hydroxybenzoate octaprenyltransferase	NA	NA	NA	NA
AUV16765.1\|1921763_1922315_-	chorismate lyase	NA	NA	NA	NA
AUV16766.1\|1922460_1922892_+	flagellar basal body-associated protein FliL	NA	NA	NA	NA
AUV16767.1\|1922948_1923119_+	hypothetical protein	NA	NA	NA	NA
AUV19076.1\|1923176_1923521_-	DUF2799 domain-containing protein	NA	NA	NA	NA
AUV16768.1\|1923683_1923806_-	hypothetical protein	NA	NA	NA	NA
AUV16769.1\|1924072_1925095_-	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	3.3e-25	27.7
AUV16770.1\|1925347_1925791_+	PTS mannitol transporter subunit IIA	NA	NA	NA	NA
AUV16771.1\|1925787_1926111_+	PTS ascorbate transporter subunit IIB	NA	NA	NA	NA
AUV16772.1\|1926170_1927427_+	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
AUV16773.1\|1927642_1928692_+	glycosyltransferase family 9 protein	NA	NA	NA	NA
AUV16774.1\|1928713_1929409_-	mannosyltransferase	NA	NA	NA	NA
AUV16775.1\|1929405_1930137_-	hypothetical protein	A0A1D8KPY1	Synechococcus_phage	7.2e-14	30.4
AUV16776.1\|1930117_1930708_-	hypothetical protein	NA	NA	NA	NA
AUV16777.1\|1930710_1931439_-	hypothetical protein	NA	NA	NA	NA
AUV16778.1\|1933273_1934233_-	ADP-L-glycero-D-mannoheptose-6-epimerase	A0A2K9L0I7	Tupanvirus	4.1e-17	26.3
AUV16779.1\|1934387_1935032_+	TetR family transcriptional regulator	NA	NA	NA	NA
AUV16780.1\|1935215_1936406_+	glycine C-acetyltransferase	V5LQ39	Emiliania_huxleyi_virus	2.2e-36	27.2
AUV16781.1\|1936495_1937521_+	L-threonine 3-dehydrogenase	R9TPW0	Vibrio_phage	4.7e-19	82.7
AUV19077.1\|1937783_1938194_+	cytochrome c5 family protein	NA	NA	NA	NA
AUV16782.1\|1938278_1940582_+	GGDEF-domain containing protein	G3MA91	Bacillus_virus	2.4e-23	34.9
AUV16783.1\|1940568_1942581_-	DNA helicase Rep	A7KV33	Bacillus_phage	1.9e-120	39.3
AUV16784.1\|1942733_1943954_+	cysteine desulfurase	Q2XUY6	environmental_halophage	3.9e-97	45.4
AUV16785.1\|1943904_1944402_+	SufE protein	NA	NA	NA	NA
AUV16786.1\|1944423_1945260_-\|tRNA	tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA	S4VW33	Pandoravirus	1.8e-16	34.4
AUV16787.1\|1945688_1946294_+	hypothetical protein	NA	NA	NA	NA
AUV16788.1\|1946286_1948521_+	hypothetical protein	NA	NA	NA	NA
AUV16789.1\|1948505_1951868_+\|integrase	site-specific integrase	NA	NA	NA	NA
1950283:1950299	attL	NA	NA	NA	NA
AUV16790.1\|1952300_1953167_-	HDIG domain-containing protein	NA	NA	NA	NA
AUV16791.1\|1953163_1954342_-\|integrase	site-specific integrase	R9TMP3	Vibrio_phage	6.8e-22	23.9
AUV16792.1\|1954351_1954564_-	hypothetical protein	NA	NA	NA	NA
AUV16793.1\|1954709_1954952_+	XRE family transcriptional regulator	NA	NA	NA	NA
AUV16794.1\|1956210_1957347_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
AUV16795.1\|1959182_1960268_+	DNA sulfur modification protein DndB	NA	NA	NA	NA
AUV16796.1\|1965272_1966304_-\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
1961770:1961786	attR	NA	NA	NA	NA
AUV16797.1\|1967532_1968483_-\|transposase	IS1595-like element ISAeca5 family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

1972264 : 2050150

Acidithiobacillus_phage(40.0%)

integrase,transposase

attL 1982241:1982300|attR 1998979:2000420

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV16801.1\|1972264_1973539_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
AUV16802.1\|1973663_1974419_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	3.4e-59	51.5
AUV16803.1\|1974433_1975975_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	3.2e-128	47.2
AUV16804.1\|1979040_1979475_-	transporter	NA	NA	NA	NA
AUV16805.1\|1979663_1981277_-\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
AUV16806.1\|1981471_1981834_-	hypothetical protein	NA	NA	NA	NA
1982241:1982300	attL	NA	NA	NA	NA
AUV16807.1\|1982520_1983657_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
AUV19078.1\|1984069_1984687_-\|integrase	integrase	K4K327	Caulobacter_virus	5.9e-09	28.0
AUV19079.1\|1985550_1986754_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	7.7e-114	70.1
AUV16808.1\|1986888_1989276_+	hypothetical protein	NA	NA	NA	NA
AUV16809.1\|1989278_1989566_-	hypothetical protein	NA	NA	NA	NA
AUV16810.1\|1990037_1991459_-\|transposase	IS66 family transposase ISKpn15	NA	NA	NA	NA
AUV16811.1\|1993416_1994976_-	hypothetical protein	NA	NA	NA	NA
AUV16812.1\|1994972_1995584_-	hypothetical protein	NA	NA	NA	NA
AUV16813.1\|1995812_1996778_-	hypothetical protein	NA	NA	NA	NA
AUV19080.1\|1996894_1998325_-\|transposase	IS4 family transposase ISAeme22	NA	NA	NA	NA
AUV16814.1\|1999258_2000395_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
AUV16815.1\|2000411_2000591_-	hypothetical protein	NA	NA	NA	NA
1998979:2000420	attR	NA	NA	NA	NA
AUV16816.1\|2000618_2001569_-\|transposase	IS1595 family transposase	NA	NA	NA	NA
AUV16817.1\|2001842_2002982_-	AraC family transcriptional regulator	NA	NA	NA	NA
AUV16818.1\|2002972_2004298_-	HAMP domain-containing protein	NA	NA	NA	NA
AUV16819.1\|2004287_2004953_-	DNA-binding response regulator	NA	NA	NA	NA
AUV16820.1\|2005120_2006437_+	ferric reductase	NA	NA	NA	NA
AUV16821.1\|2006513_2006894_+	PepSY domain-containing protein	NA	NA	NA	NA
AUV16822.1\|2006948_2007422_+	DUF2271 domain-containing protein	NA	NA	NA	NA
AUV16823.1\|2007444_2009661_+	nitric oxide synthase	NA	NA	NA	NA
AUV16824.1\|2009736_2010489_+	hypothetical protein	NA	NA	NA	NA
AUV16825.1\|2011201_2012476_+\|transposase	IS4 family transposase	NA	NA	NA	NA
AUV16826.1\|2013380_2014136_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.4e-52	45.0
AUV16827.1\|2014158_2015724_-\|transposase	IS21 family transposase ISAs27	K4I413	Acidithiobacillus_phage	2.9e-121	45.8
AUV16828.1\|2017837_2018638_+	heme ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	2.3e-13	26.7
AUV16829.1\|2018887_2019496_-	YitT family protein	NA	NA	NA	NA
AUV16830.1\|2019540_2019762_+	hypothetical protein	NA	NA	NA	NA
AUV19081.1\|2019799_2021161_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	3.3e-81	38.0
AUV16831.1\|2021157_2022156_+	NAD-dependent epimerase	A0A1V0SKV4	Klosneuvirus	5.7e-30	30.8
AUV16832.1\|2022239_2023928_-	glycosyltransferase family 39 protein	NA	NA	NA	NA
AUV16833.1\|2023917_2024283_-	hypothetical protein	NA	NA	NA	NA
AUV16834.1\|2026259_2027015_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	3.4e-59	51.5
AUV19082.1\|2028254_2029459_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	7.7e-114	70.1
AUV16835.1\|2031126_2031474_+	DNA sulfur modification protein DndE	NA	NA	NA	NA
AUV16836.1\|2032137_2033169_+\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
AUV16837.1\|2033634_2034408_-	hypothetical protein	A0A1B0V7H9	Salmonella_phage	5.4e-36	100.0
AUV16838.1\|2034716_2036294_+	chemotaxis protein	A0A1B0V854	Salmonella_phage	8.0e-95	97.8
AUV16839.1\|2036478_2037495_+\|transposase	IS5/IS1182 family transposase	Q38213	Escherichia_phage	1.4e-185	98.8
AUV16840.1\|2037601_2038876_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
AUV16841.1\|2039360_2040392_+\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
AUV16842.1\|2040416_2045519_-	DNA phosphorothioation-dependent restriction protein DptH	NA	NA	NA	NA
AUV16843.1\|2045499_2046828_-	DNA phosphorothioation-dependent restriction protein DptG	NA	NA	NA	NA
AUV16844.1\|2046830_2048417_-	DNA phosphorothioation-dependent restriction protein DptF	NA	NA	NA	NA
AUV16845.1\|2048608_2050150_+\|transposase	IS21-like element ISAs29 family transposase	K4I413	Acidithiobacillus_phage	4.4e-130	47.6

DBSCAN-SWA_10

2295190 : 2351923

Acidithiobacillus_phage(22.22%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV19104.1\|2295190_2295379_+\|holin	holin	NA	NA	NA	NA
AUV17021.1\|2295494_2296331_-	mechanosensitive ion channel protein	NA	NA	NA	NA
AUV17022.1\|2296837_2297434_-	nucleoid occlusion factor SlmA	NA	NA	NA	NA
AUV17023.1\|2297504_2297963_-	dUTP diphosphatase	Q2NP83	Xanthomonas_phage	1.4e-52	64.0
AUV17024.1\|2298039_2299242_-	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	6.4e-44	34.0
AUV17025.1\|2299389_2300064_+	JAB domain-containing protein	NA	NA	NA	NA
AUV17026.1\|2300200_2300437_+	50S ribosomal protein L28	NA	NA	NA	NA
AUV17027.1\|2300448_2300616_+	50S ribosomal protein L33	NA	NA	NA	NA
AUV17028.1\|2300706_2301162_+	hypothetical protein	NA	NA	NA	NA
AUV17029.1\|2301176_2301989_+	bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase	A0A127AWE5	Bacillus_phage	6.1e-22	30.0
AUV17030.1\|2302165_2303038_+	DUF535 domain-containing protein	NA	NA	NA	NA
AUV17031.1\|2303111_2303594_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	1.8e-29	46.8
AUV17032.1\|2303815_2304859_+	lipopolysaccharide heptosyltransferase family protein	NA	NA	NA	NA
AUV19105.1\|2305199_2305976_-	glycosyltransferase family 2 protein	A0A1C3NFH8	Phage_NCTB	2.2e-05	35.8
AUV17033.1\|2306315_2307413_+	lipopolysaccharide heptosyltransferase II	NA	NA	NA	NA
AUV17034.1\|2307414_2308683_+	3-deoxy-D-manno-octulosonic acid transferase	NA	NA	NA	NA
AUV17035.1\|2308794_2309673_+	EamA/RhaT family transporter	NA	NA	NA	NA
AUV17036.1\|2309856_2310720_-	YicC family protein	NA	NA	NA	NA
AUV17037.1\|2310809_2311583_+	ribonuclease PH	NA	NA	NA	NA
AUV17038.1\|2311924_2312578_+	orotate phosphoribosyltransferase	NA	NA	NA	NA
AUV17039.1\|2312757_2315187_+	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.7e-107	36.7
AUV17040.1\|2315183_2315573_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
AUV19106.1\|2315765_2316881_+	GGDEF domain-containing protein	NA	NA	NA	NA
AUV17041.1\|2316911_2317175_+	DUF1040 domain-containing protein	NA	NA	NA	NA
AUV17042.1\|2317372_2318821_+	cytochrome c oxidase accessory protein CcoG	NA	NA	NA	NA
AUV17043.1\|2318895_2319885_+	serine/threonine protein kinase	NA	NA	NA	NA
AUV17044.1\|2320094_2320703_+	thiol:disulfide interchange protein DsbA/DsbL	NA	NA	NA	NA
AUV17045.1\|2320777_2321956_-	nicotinate phosphoribosyltransferase	NA	NA	NA	NA
AUV17046.1\|2322057_2322693_-	nicotinamidase	NA	NA	NA	NA
AUV17047.1\|2322767_2323418_+	DNA mismatch repair protein MutT	NA	NA	NA	NA
AUV17048.1\|2323494_2323980_+	DUF523 domain-containing protein	NA	NA	NA	NA
AUV17049.1\|2323925_2324882_-	acyltransferase	NA	NA	NA	NA
AUV17050.1\|2324889_2325789_-	acyltransferase	NA	NA	NA	NA
AUV19107.1\|2326710_2327400_+\|transposase	heteromeric transposase endonuclease subunit TnsA	NA	NA	NA	NA
AUV17051.1\|2329317_2330208_+\|transposase	transposase	NA	NA	NA	NA
AUV17052.1\|2330165_2331299_+	hypothetical protein	NA	NA	NA	NA
AUV17053.1\|2331548_2331779_+	hypothetical protein	NA	NA	NA	NA
AUV17054.1\|2332051_2332726_+	hypothetical protein	NA	NA	NA	NA
AUV17055.1\|2332715_2332898_-	hypothetical protein	NA	NA	NA	NA
AUV17056.1\|2334985_2336527_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	5.8e-130	47.6
AUV17057.1\|2336540_2337296_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	4.4e-59	51.5
AUV17058.1\|2338087_2339944_-	hypothetical protein	NA	NA	NA	NA
AUV17059.1\|2339970_2341116_-	DNA (cytosine-5-)-methyltransferase	M1PSQ0	Streptococcus_phage	2.0e-42	32.7
AUV17060.1\|2342340_2343741_-	ATP-binding protein	NA	NA	NA	NA
AUV17061.1\|2344058_2344331_-	hypothetical protein	NA	NA	NA	NA
AUV17062.1\|2344423_2345845_+\|transposase	IS66 family transposase ISKpn15	NA	NA	NA	NA
AUV17063.1\|2346575_2348966_-	hypothetical protein	NA	NA	NA	NA
AUV17064.1\|2348962_2350753_-	hypothetical protein	NA	NA	NA	NA
AUV17065.1\|2350891_2351923_-\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_11

2547038 : 2611395

Bacillus_virus(16.67%)

integrase,transposase

attL 2596323:2596338|attR 2614426:2614441

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV17220.1\|2547038_2548376_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
AUV17221.1\|2548425_2549505_-	hypothetical protein	NA	NA	NA	NA
AUV17222.1\|2549520_2550915_-	phosphatidic acid phosphatase	NA	NA	NA	NA
AUV19114.1\|2551069_2551447_+	hypothetical protein	NA	NA	NA	NA
AUV17223.1\|2551527_2552934_-	hypothetical protein	NA	NA	NA	NA
AUV17224.1\|2553153_2553471_+	DUF1496 domain-containing protein	NA	NA	NA	NA
AUV17225.1\|2554490_2555939_-	catalase	A0A2K9L0T1	Tupanvirus	7.1e-98	47.3
AUV17226.1\|2556091_2556580_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AUV17227.1\|2556576_2557434_+	AraC family transcriptional regulator	NA	NA	NA	NA
AUV17228.1\|2557503_2558403_-	EamA/RhaT family transporter	NA	NA	NA	NA
AUV19115.1\|2558512_2558953_-	DUF2214 domain-containing protein	NA	NA	NA	NA
AUV17229.1\|2559063_2560668_+	sensor domain-containing diguanylate cyclase	G3MA91	Bacillus_virus	1.4e-09	26.9
AUV17230.1\|2560691_2561351_-	HAD-IB family hydrolase	NA	NA	NA	NA
AUV17231.1\|2561416_2562424_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.4e-29	34.3
AUV17232.1\|2562430_2563207_-	ABC transporter permease	NA	NA	NA	NA
AUV17233.1\|2563199_2564096_-	ABC transporter permease	NA	NA	NA	NA
AUV17234.1\|2564095_2564929_-	alkaline phosphatase family protein	NA	NA	NA	NA
AUV17235.1\|2564939_2565986_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
AUV19116.1\|2566184_2566982_+	UTRA domain-containing protein	NA	NA	NA	NA
AUV17236.1\|2567028_2567793_-	XRE family transcriptional regulator	NA	NA	NA	NA
AUV17237.1\|2568236_2569151_-	LysR family transcriptional regulator	NA	NA	NA	NA
AUV17238.1\|2569408_2569741_+	hypothetical protein	NA	NA	NA	NA
AUV19117.1\|2569771_2570458_+	pirin family protein	NA	NA	NA	NA
AUV17239.1\|2570541_2570934_+	DoxX family protein	NA	NA	NA	NA
AUV17240.1\|2571166_2574523_+	exodeoxyribonuclease V subunit gamma	NA	NA	NA	NA
AUV17241.1\|2574522_2578137_+	exodeoxyribonuclease V subunit beta	A7KV33	Bacillus_phage	1.8e-09	21.7
AUV17242.1\|2578145_2580200_+	exodeoxyribonuclease V subunit alpha	A0A1P8DII4	Virus_Rctr197k	1.1e-27	27.1
AUV17243.1\|2580202_2580757_+	hypothetical protein	NA	NA	NA	NA
AUV19118.1\|2580838_2581438_+	hypothetical protein	NA	NA	NA	NA
AUV17244.1\|2581606_2583220_-\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
AUV17245.1\|2583487_2583886_-	glyoxalase	NA	NA	NA	NA
AUV19119.1\|2583964_2584876_+	AraC family transcriptional regulator	NA	NA	NA	NA
AUV17246.1\|2584935_2586177_-	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	1.4e-57	37.0
AUV17247.1\|2586202_2586541_-	transcriptional regulator	NA	NA	NA	NA
AUV17248.1\|2586927_2587929_+	sensor domain-containing diguanylate cyclase	NA	NA	NA	NA
AUV17249.1\|2588058_2588472_+	hypothetical protein	NA	NA	NA	NA
AUV17250.1\|2588534_2590529_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	6.3e-28	47.7
AUV17251.1\|2591015_2591372_-	hypothetical protein	NA	NA	NA	NA
AUV19120.1\|2591571_2592294_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	5.2e-33	36.7
AUV17252.1\|2593863_2594076_-	cold-shock protein	A0A1W6JNX5	Morganella_phage	3.9e-21	73.5
AUV17253.1\|2594464_2594749_-	hypothetical protein	NA	NA	NA	NA
AUV19121.1\|2595044_2595167_+	hypothetical protein	NA	NA	NA	NA
2596323:2596338	attL	NA	NA	NA	NA
AUV17254.1\|2597530_2597839_-	XRE family transcriptional regulator	NA	NA	NA	NA
AUV17255.1\|2597937_2598408_+	hypothetical protein	NA	NA	NA	NA
AUV17256.1\|2598617_2598809_+	hypothetical protein	NA	NA	NA	NA
AUV17257.1\|2599016_2600033_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.9e-186	99.4
AUV19122.1\|2600070_2600199_-	sugar kinase	Q6QLL3	Human_immunodeficiency_virus	4.0e-13	97.2
AUV17258.1\|2600307_2601921_-\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
AUV17259.1\|2602067_2602703_-	tetracycline repressor protein class E	NA	NA	NA	NA
AUV17260.1\|2603816_2604848_+\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
AUV17261.1\|2605248_2605917_-	hypothetical protein	NA	NA	NA	NA
AUV17262.1\|2606454_2608617_-	AAA family ATPase	A0A2I2L5Q3	Orpheovirus	1.8e-20	26.2
AUV17263.1\|2608613_2609051_-	hypothetical protein	NA	NA	NA	NA
AUV17264.1\|2609050_2609530_-	hypothetical protein	NA	NA	NA	NA
AUV17265.1\|2609517_2611395_-\|integrase	integrase	NA	NA	NA	NA
2614426:2614441	attR	NA	NA	NA	NA

DBSCAN-SWA_12

3371790 : 3423731

Acinetobacter_phage(14.29%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV17858.1\|3371790_3372795_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
AUV17859.1\|3372914_3373130_+	hypothetical protein	NA	NA	NA	NA
AUV17860.1\|3373451_3374033_+	aminodeoxychorismate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	7.3e-70	62.5
AUV17861.1\|3374310_3375528_+	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	4.0e-25	27.1
AUV17862.1\|3375603_3376623_+	arginine N-succinyltransferase	NA	NA	NA	NA
AUV17863.1\|3376690_3378160_+	succinylglutamate-semialdehyde dehydrogenase	NA	NA	NA	NA
AUV17864.1\|3378229_3379027_+	DUF1338 domain-containing protein	NA	NA	NA	NA
AUV17865.1\|3379207_3379459_+	hypothetical protein	NA	NA	NA	NA
AUV17866.1\|3379498_3380125_-	beta-phosphoglucomutase family hydrolase	A0A1D8KPI1	Synechococcus_phage	9.2e-10	26.8
AUV19176.1\|3381756_3382113_-	DUF1622 domain-containing protein	NA	NA	NA	NA
AUV17867.1\|3382204_3383125_-	alpha/beta hydrolase	L7RDF8	Acanthamoeba_polyphaga_moumouvirus	1.3e-25	32.0
AUV17868.1\|3383212_3383545_-	ASCH domain-containing protein	NA	NA	NA	NA
AUV17869.1\|3383815_3385648_+	SLC13 family permease	NA	NA	NA	NA
AUV17870.1\|3387105_3388527_-\|transposase	IS66 family transposase ISKpn15	NA	NA	NA	NA
AUV17871.1\|3388960_3389248_-	hypothetical protein	NA	NA	NA	NA
AUV17872.1\|3389660_3390935_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
AUV17873.1\|3391970_3392183_+	AlpA family transcriptional regulator	NA	NA	NA	NA
AUV17874.1\|3392361_3393228_+	RepA	NA	NA	NA	NA
AUV17875.1\|3393688_3393919_-	XRE family transcriptional regulator	NA	NA	NA	NA
AUV19177.1\|3394336_3394828_+	hypothetical protein	NA	NA	NA	NA
AUV17876.1\|3394847_3395492_+	hypothetical protein	NA	NA	NA	NA
AUV17877.1\|3395451_3396006_+	molybdenum cofactor carrier	NA	NA	NA	NA
AUV17878.1\|3395992_3396277_+	hypothetical protein	NA	NA	NA	NA
AUV17879.1\|3396302_3396743_-	hypothetical protein	NA	NA	NA	NA
AUV17880.1\|3396864_3397422_-	recombinase family protein	A0A0C4UR34	Shigella_phage	3.3e-59	63.2
AUV17881.1\|3397415_3397787_-	hypothetical protein	NA	NA	NA	NA
AUV17882.1\|3397783_3398284_-\|transposase	transposase	NA	NA	NA	NA
AUV17883.1\|3398280_3398607_-	hypothetical protein	NA	NA	NA	NA
AUV17884.1\|3398861_3399218_-	cupin domain-containing protein	NA	NA	NA	NA
AUV17885.1\|3399454_3399841_-	DUF86 domain-containing protein	NA	NA	NA	NA
AUV17886.1\|3399837_3400128_-	nucleotidyltransferase	NA	NA	NA	NA
AUV17887.1\|3400262_3400838_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	5.6e-46	52.7
AUV17888.1\|3400964_3401393_-	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	NA	NA	NA	NA
AUV17889.1\|3401992_3402481_+	DUF417 domain-containing protein	NA	NA	NA	NA
AUV19178.1\|3402539_3402722_+	hypothetical protein	NA	NA	NA	NA
AUV17890.1\|3402957_3403533_+	MarR family transcriptional regulator	NA	NA	NA	NA
AUV17891.1\|3403929_3404955_-	oxidoreductase	NA	NA	NA	NA
AUV19179.1\|3404954_3405548_-	peptide-methionine (S)-S-oxide reductase	NA	NA	NA	NA
AUV17892.1\|3405550_3406783_-	OsmC family protein	NA	NA	NA	NA
AUV17893.1\|3406927_3407887_+	LysR family transcriptional regulator	NA	NA	NA	NA
AUV17894.1\|3408033_3408477_+	peptide-methionine (R)-S-oxide reductase	NA	NA	NA	NA
AUV17895.1\|3408478_3409018_+	peptide-methionine (S)-S-oxide reductase	NA	NA	NA	NA
AUV17896.1\|3409150_3409855_+	glutathione S-transferase	NA	NA	NA	NA
AUV17897.1\|3409851_3410820_+	magnesium and cobalt transport protein CorA	NA	NA	NA	NA
AUV17898.1\|3410911_3411484_+	hypothetical protein	NA	NA	NA	NA
AUV17899.1\|3411571_3412021_+	hypothetical protein	NA	NA	NA	NA
AUV17900.1\|3412127_3412529_+	hypothetical protein	NA	NA	NA	NA
AUV17901.1\|3412559_3413831_-	MFS transporter	NA	NA	NA	NA
AUV17902.1\|3413818_3414331_-	hypothetical protein	NA	NA	NA	NA
AUV17903.1\|3414334_3414805_-	thiol-disulfide isomerase	NA	NA	NA	NA
AUV19180.1\|3414956_3415247_-	DUF1330 domain-containing protein	NA	NA	NA	NA
AUV17904.1\|3415309_3415741_-	heme-binding protein	NA	NA	NA	NA
AUV17905.1\|3415814_3416825_-	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
AUV17906.1\|3417434_3418703_-\|transposase	IS4 family transposase ISApu1	NA	NA	NA	NA
AUV17907.1\|3419020_3419392_-	hypothetical protein	NA	NA	NA	NA
AUV17908.1\|3419548_3420823_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
AUV17909.1\|3420803_3423731_-\|transposase	Tn3-like element TnAs1 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	99.4

DBSCAN-SWA_13

3469988 : 3592570

Escherichia_phage(11.11%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV17949.1\|3469988_3470528_-\|protease	SprT family zinc-dependent metalloprotease	A0A060AI19	Cronobacter_phage	1.4e-06	29.5
AUV17950.1\|3470595_3471747_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-130	62.8
AUV17951.1\|3472087_3474079_+	transketolase	NA	NA	NA	NA
AUV19184.1\|3474258_3474774_+	hypothetical protein	NA	NA	NA	NA
AUV17952.1\|3474760_3475402_+	hypothetical protein	NA	NA	NA	NA
AUV17953.1\|3475465_3476731_-	reactive intermediate/imine deaminase	NA	NA	NA	NA
AUV19185.1\|3478041_3478341_+	hypothetical protein	NA	NA	NA	NA
AUV17954.1\|3478453_3479578_-	anhydro-N-acetylmuramic acid kinase	NA	NA	NA	NA
AUV17955.1\|3479642_3480953_-	peptidase M23	A0A1P8BKT8	Lactococcus_phage	5.0e-18	48.7
AUV17956.1\|3481067_3482267_+\|tRNA	tyrosine--tRNA ligase	NA	NA	NA	NA
AUV17957.1\|3482587_3483391_-	AraC family transcriptional regulator	NA	NA	NA	NA
AUV17958.1\|3483402_3483936_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
AUV17959.1\|3484113_3485370_-	adenylosuccinate synthetase	G5CQQ4	Megavirus	5.9e-48	31.8
AUV17960.1\|3485560_3486463_+	LysR family transcriptional regulator	NA	NA	NA	NA
AUV17961.1\|3486526_3487873_-	immunogenic protein	NA	NA	NA	NA
AUV17962.1\|3488021_3489161_-	aspartate aminotransferase	NA	NA	NA	NA
AUV17963.1\|3489325_3490498_+	MFS transporter	NA	NA	NA	NA
AUV17964.1\|3490569_3491454_-	LysR family transcriptional regulator	NA	NA	NA	NA
AUV17965.1\|3491543_3492299_-	YciK family oxidoreductase	NA	NA	NA	NA
AUV17966.1\|3492523_3493531_+\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	1.9e-17	28.1
AUV17967.1\|3493761_3495099_-	N-succinylarginine dihydrolase	NA	NA	NA	NA
AUV17968.1\|3495458_3498080_+	type I DNA topoisomerase	A0A1V0SB35	Catovirus	1.6e-87	34.5
AUV17969.1\|3498448_3498799_-	cysteine methyltransferase	NA	NA	NA	NA
AUV17970.1\|3498865_3500419_-	aerotaxis receptor Aer	A0A1B0V854	Salmonella_phage	1.6e-34	42.6
AUV17971.1\|3500611_3502468_-	beta-hexosaminidase	A0A076G5S5	Staphylococcus_phage	1.4e-08	23.2
AUV17972.1\|3502535_3503408_-	N-acetylglucosamine kinase	NA	NA	NA	NA
AUV17973.1\|3503512_3505240_-	chitobiase	NA	NA	NA	NA
AUV17974.1\|3505347_3506346_-	ABC transporter ATP-binding protein	F2Y1V6	Organic_Lake_phycodnavirus	3.1e-07	25.9
AUV17975.1\|3507375_3508281_-	ABC transporter permease	NA	NA	NA	NA
AUV17976.1\|3508282_3509266_-	ABC transporter permease	NA	NA	NA	NA
AUV17977.1\|3509383_3511066_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
AUV19186.1\|3511611_3512937_-	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
AUV17978.1\|3513338_3513548_+	hypothetical protein	NA	NA	NA	NA
AUV17979.1\|3516074_3516989_+	hypothetical protein	NA	NA	NA	NA
AUV17980.1\|3517090_3518122_+\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
AUV17981.1\|3518347_3519046_+	hypothetical protein	NA	NA	NA	NA
AUV17982.1\|3519554_3520682_+	DUF4172 domain-containing protein	D7RWK9	Brochothrix_phage	1.7e-06	25.7
AUV17983.1\|3520757_3521018_-	hypothetical protein	NA	NA	NA	NA
AUV17984.1\|3521079_3521490_-	transcriptional regulator	NA	NA	NA	NA
AUV17985.1\|3521841_3522141_-	hypothetical protein	NA	NA	NA	NA
AUV17986.1\|3522406_3523828_-\|transposase	IS66 family transposase ISKpn15	NA	NA	NA	NA
AUV17987.1\|3524267_3524591_+	hypothetical protein	NA	NA	NA	NA
AUV17988.1\|3524782_3525469_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	2.3e-30	34.5
AUV17989.1\|3525458_3526826_+\|tRNA	tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase	A0A1V0SGX0	Hokovirus	9.3e-07	23.9
AUV17990.1\|3529096_3530710_-\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
AUV17991.1\|3530897_3531431_-	hypothetical protein	NA	NA	NA	NA
AUV17992.1\|3531451_3532309_-	copper resistance protein B	NA	NA	NA	NA
AUV19187.1\|3532320_3534255_-	copper resistance system multicopper oxidase	NA	NA	NA	NA
AUV17993.1\|3534393_3534720_-	hypothetical protein	NA	NA	NA	NA
AUV17994.1\|3534964_3535858_+\|transposase	IS5/IS1182 family transposase	Q38213	Escherichia_phage	7.4e-154	86.2
AUV17995.1\|3536226_3537501_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
AUV17996.1\|3537899_3538352_+	hypothetical protein	NA	NA	NA	NA
AUV17997.1\|3539046_3540537_+	sodium-independent anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	2.0e-220	81.6
AUV17998.1\|3540556_3541402_+	universal stress protein UspA	A0A2H4J154	uncultured_Caudovirales_phage	1.9e-63	46.3
AUV19188.1\|3541547_3542751_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	1.2e-114	70.5
AUV17999.1\|3542952_3543708_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	3.4e-59	51.5
AUV18000.1\|3543722_3545264_-\|transposase	IS21-like element ISAs29 family transposase	K4I413	Acidithiobacillus_phage	4.4e-130	47.6
AUV18001.1\|3549557_3549740_-	hypothetical protein	NA	NA	NA	NA
AUV18002.1\|3552182_3552938_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.4e-52	45.0
AUV18003.1\|3555909_3556941_-\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
AUV19189.1\|3557633_3558155_-	hypothetical protein	NA	NA	NA	NA
AUV18004.1\|3558180_3561249_-	DEAD/DEAH box helicase	NA	NA	NA	NA
AUV18005.1\|3561245_3562568_-	hypothetical protein	NA	NA	NA	NA
AUV18006.1\|3562642_3564049_-	restriction endonuclease subunit S	NA	NA	NA	NA
AUV18007.1\|3564048_3566427_-	N-6 DNA methylase	NA	NA	NA	NA
AUV18008.1\|3566438_3568169_-	DUF262 domain-containing protein	NA	NA	NA	NA
AUV18009.1\|3568183_3569092_-	WYL domain-containing protein	NA	NA	NA	NA
AUV18010.1\|3569793_3570810_-\|transposase	IS5/IS1182 family transposase	Q38213	Escherichia_phage	7.8e-184	97.9
AUV18011.1\|3571306_3571480_-	virulence-associated protein MvpT	NA	NA	NA	NA
AUV18012.1\|3571529_3572447_+\|transposase	IS5/IS1182 family transposase	A0A1V0E8E1	Vibrio_phage	2.6e-98	58.2
AUV18013.1\|3572726_3573149_+	translesion error-prone DNA polymerase V subunit UmuD	A0A1W6JNS2	Morganella_phage	1.5e-35	55.9
AUV18014.1\|3573152_3574424_+	protein UmuC	F1C5A5	Cronobacter_phage	1.5e-128	54.9
AUV19190.1\|3575110_3576040_+	DNA-processing protein DprA	NA	NA	NA	NA
AUV18015.1\|3576036_3580713_+	RecQ family ATP-dependent DNA helicase	K7YHB4	Megavirus	2.1e-34	31.7
AUV19191.1\|3580709_3581195_+	hypothetical protein	NA	NA	NA	NA
AUV18016.1\|3582363_3582567_+	hypothetical protein	NA	NA	NA	NA
AUV18017.1\|3582683_3584315_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	3.9e-44	38.0
AUV18018.1\|3584611_3585880_-\|transposase	IS4-like element ISAeme4 family transposase	NA	NA	NA	NA
AUV18019.1\|3586074_3586785_-	hypothetical protein	NA	NA	NA	NA
AUV18020.1\|3586807_3588157_-	hypothetical protein	NA	NA	NA	NA
AUV18021.1\|3589472_3590489_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	1.4e-185	99.1
AUV18022.1\|3590526_3590745_-	hypothetical protein	Q6QLL3	Human_immunodeficiency_virus	1.5e-07	100.0
AUV18023.1\|3591482_3592570_-\|transposase	IS3-like element ISAs22 family transposase	NA	NA	NA	NA

DBSCAN-SWA_14

3669014 : 3695986

Escherichia_phage(25.0%)

integrase,transposase

attL 3658283:3658298|attR 3701700:3701715

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3658283:3658298	attL	NA	NA	NA	NA
AUV18096.1\|3669014_3670046_-\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
AUV18097.1\|3670300_3671317_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.9e-186	99.4
AUV18098.1\|3672503_3672791_+	hypothetical protein	NA	NA	NA	NA
AUV18099.1\|3672787_3673006_-	hypothetical protein	NA	NA	NA	NA
AUV18100.1\|3673116_3674256_+	DUF4172 domain-containing protein	D7RWK9	Brochothrix_phage	4.3e-05	29.8
AUV18101.1\|3674557_3674908_+	NIPSNAP family protein	NA	NA	NA	NA
AUV18102.1\|3675013_3675274_-	hypothetical protein	NA	NA	NA	NA
AUV18103.1\|3675335_3675743_-	transcriptional regulator	NA	NA	NA	NA
AUV18104.1\|3676096_3676396_-	hypothetical protein	NA	NA	NA	NA
AUV18105.1\|3676508_3676700_-	hypothetical protein	NA	NA	NA	NA
AUV19195.1\|3677177_3677621_+	DUF2384 domain-containing protein	NA	NA	NA	NA
AUV18106.1\|3678931_3680155_+	hypothetical protein	NA	NA	NA	NA
AUV18107.1\|3680173_3680986_+	macrocin-O-methyltransferase	A0A285PWA5	Cedratvirus	3.3e-36	42.8
AUV19196.1\|3680967_3682194_+	MFS transporter	NA	NA	NA	NA
AUV18108.1\|3682371_3683403_+\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
AUV18109.1\|3683498_3684323_-	hypothetical protein	NA	NA	NA	NA
AUV18110.1\|3684828_3687690_+	helicase IV	A0A2H4UW05	Bodo_saltans_virus	1.2e-11	25.1
AUV18111.1\|3688538_3689570_-\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
AUV18112.1\|3691546_3692968_+\|transposase	IS66 family transposase ISKpn15	NA	NA	NA	NA
AUV18113.1\|3694378_3695986_-\|integrase	site-specific integrase	NA	NA	NA	NA
3701700:3701715	attR	NA	NA	NA	NA

DBSCAN-SWA_15

3986304 : 4026561

Vibrio_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUV18342.1\|3986304_3987336_+\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
AUV18343.1\|3987563_3988709_+	dTDP-4-amino-4,6-dideoxygalactose transaminase	A0A0P0YLZ6	Yellowstone_lake_phycodnavirus	5.6e-13	27.4
AUV18344.1\|3988937_3989594_-	class I SAM-dependent methyltransferase	A0A2P0VPE2	Tetraselmis_virus	2.8e-09	28.7
AUV18345.1\|3989721_3990855_-	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine transaminase	A0A2K9L0G1	Tupanvirus	2.1e-28	32.1
AUV18346.1\|3990851_3991856_-	UDP-N-acetylglucosamine 4,6-dehydratase (inverting)	A0A1V0SAI8	Catovirus	5.7e-38	35.2
AUV18347.1\|3992012_3992870_-	cobalamin-binding protein	NA	NA	NA	NA
AUV19219.1\|3992862_3993762_-	cobalamin biosynthesis protein CobD	NA	NA	NA	NA
AUV18348.1\|3993821_3994514_-	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	NA	NA	NA	NA
AUV18349.1\|3994743_3995673_-	hypothetical protein	NA	NA	NA	NA
AUV18350.1\|3997047_3998274_+\|transposase	transposase	O80301	Enterobacteria_phage	1.0e-153	78.6
AUV18351.1\|3999469_3999877_-	lactoylglutathione lyase	NA	NA	NA	NA
AUV18352.1\|4000609_4001368_-	electron transport complex subunit RsxE	NA	NA	NA	NA
AUV18353.1\|4001384_4002017_-	electron transport complex subunit RsxG	NA	NA	NA	NA
AUV18354.1\|4002060_4003113_-	electron transport complex subunit RsxD	NA	NA	NA	NA
AUV18355.1\|4005744_4006311_-	electron transport complex subunit RsxB	NA	NA	NA	NA
AUV18356.1\|4006315_4006897_-	electron transport complex subunit RsxA	NA	NA	NA	NA
AUV18357.1\|4007048_4007309_-\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	7.1e-25	78.9
AUV18358.1\|4007290_4008349_-\|transposase	ISAs1 family transposase ISSba1	NA	NA	NA	NA
AUV18359.1\|4008311_4009328_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
AUV18360.1\|4009797_4010514_-	hypothetical protein	NA	NA	NA	NA
AUV18361.1\|4010582_4010921_-	hypothetical protein	NA	NA	NA	NA
AUV18362.1\|4011226_4012525_+	hypothetical protein	NA	NA	NA	NA
AUV18363.1\|4012521_4012890_+	hypothetical protein	B7SYE8	Stenotrophomonas_phage	4.7e-06	32.4
AUV18364.1\|4015734_4015959_+	hypothetical protein	NA	NA	NA	NA
AUV18365.1\|4016161_4017355_+	enoyl-[acyl-carrier-protein] reductase FabV	NA	NA	NA	NA
AUV18366.1\|4017517_4018993_+	C4-dicarboxylate ABC transporter	NA	NA	NA	NA
AUV18367.1\|4019058_4020273_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
AUV18368.1\|4020629_4020839_+	DUF1653 domain-containing protein	M5ABZ3	Bacillus_phage	1.2e-09	50.8
AUV18369.1\|4020898_4021156_-	GrxA family glutaredoxin	A0A2I7SAE2	Vibrio_phage	7.3e-22	59.0
AUV18370.1\|4022892_4024653_-	ATP-dependent helicase	M4Q3N1	Vibrio_phage	4.9e-93	41.7
AUV18371.1\|4024775_4025813_-	HlyD family secretion protein	NA	NA	NA	NA
AUV18372.1\|4025823_4026093_-	DUF3302 domain-containing protein	NA	NA	NA	NA
AUV18373.1\|4026156_4026561_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	6.7e-30	54.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP026227

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP026226

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection