CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP026649	Bacillus coagulans strain R11 chromosome, complete genome	12 crisprs	cas14j,cas5,cas8c,cas7,DinG,casR,cas3,DEDDh,csa3,cas2,cas1,cas4	2	15	13	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP026649_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026649_2

302848-302985

Orphan

Consensus_repeat	Method
GTCTTTTAAAGGCCTTCAAAAAGACAAAAAGGA	PILER-CR

2 spacers

The CRISPR arrays of CP026649_2

>merge|CP026649|2|302848-302985|PILER-CR
GTCTTTTACAGGCTTTCAAAAAGACAAAAAGGGATCAGGCCAGAGCTCAAAATGTCCCCTAGAAGCCGTCAAAAAGACAAAAAGGAATGGGATCCGCCCCCAAATGTCTTTTTAAGACGTTTAAAAAGACAAAAAGGA

>CP026649|2|1|302848-302985|PILER-CR
GTCTTTTACAGGCTTTCAAAAAGACAAAAAGGGATCAGGCCAGAGCTCAAA	ATGTCCCCTAGAA
GCCGTCAAAAAGACAAAAAGGAATGGGATCCGCCCCCAAATGTCTTTTTAA	GACGTTTAAAAAGACAAAA
AGGA

Protein	Signature genes	Signature genes Name	Protein_function
CP026649.1\|AVD54939.1\|299858_300917_+\|phosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|270703
CP026649.1\|AVD54933.1\|293150_294170_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|132912
CP026649.1\|AVD54949.1\|311838_312369_+\|YbaK/EbsC-family-protein	unknown	unknown	gnl\|CDD\|239825
CP026649.1\|AVD54934.1\|294357_295602_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173844
CP026649.1\|AVD54945.1\|309287_310046_+\|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl\|CDD\|381169
CP026649.1\|AVD54948.1\|311079_311706_+\|siroheme-synthase	unknown	unknown	gnl\|CDD\|180667
CP026649.1\|AVD54941.1\|305762_307166_-\|pectate-lyase	unknown	unknown	gnl\|CDD\|378931
CP026649.1\|AVD54935.1\|295579_296353_+\|gluconate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|181295
CP026649.1\|AVD54931.1\|291936_292140_-\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD54950.1\|313977_315081_-\|glycerol-dehydrogenase	unknown	unknown	gnl\|CDD\|181843
CP026649.1\|AVD54947.1\|310835_311060_+\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD54938.1\|299411_299816_+\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
CP026649.1\|AVD54936.1\|298121_298685_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380061
CP026649.1\|AVD54942.1\|307335_307641_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274982
CP026649.1\|AVD54943.1\|308162_308888_+\|phosphoadenylyl-sulfate-reductase	unknown	unknown	gnl\|CDD\|129526
CP026649.1\|AVD54932.1\|292232_292952_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237084
CP026649.1\|AVD54944.1\|309111_309291_+\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD54946.1\|310052_310793_+\|sirohydrochlorin-chelatase	unknown	unknown	gnl\|CDD\|225049
CP026649.1\|AVD54940.1\|301300_302719_+\|NAD-dependent-succinate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143421
CP026649.1\|AVD54937.1\|298837_299026_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP026649.1\|AVD54939.1\|299858_300917_+\|phosphotransferase-family-protein	gnl\|CDD\|270703	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins. This subfamily is composed of the N-terminal domains of vertebrate ACAD10 and ACAD11, and similar uncharacterized bacterial and eukaryotic proteins. ACADs are a family of flavoproteins that are involved in the beta-oxidation of fatty acyl-CoA derivatives. ACAD deficiency can cause metabolic disorders including muscle fatigue, hypoglycemia, and hepatic lipidosis. There are at least 11 distinct ACADs, some of which show distinct substrate specificities to either straight-chain or branched-chain fatty acids. ACAD10 is widely expressed in human tissues and highly expressed in liver, kidney, pancreas, and spleen. ACAD10 and ACAD11 are both significantly expressed in human brain tissues. They contain a long N-terminal domain with similarity to phosphotransferases with a Protein Kinase fold, which is absent in other ACADs. They may exhibit multiple functions in acyl-CoA oxidation pathways. ACAD11 utilizes substrates with carbon chain lengths of 20 to 26, with optimal activity towards C22CoA. ACAD10 may be associated with an increased risk in type II diabetes. The ACAD10/11-like subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	1.15639e-89
CP026649.1\|AVD54933.1\|293150_294170_+\|STAS-domain-containing-protein	gnl\|CDD\|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	4.16707e-36
CP026649.1\|AVD54934.1\|294357_295602_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|173844	cd01155, ACAD_FadE2, Acyl-CoA dehydrogenases similar to fadE2. FadE2-like Acyl-CoA dehydrogenase (ACAD). Acyl-CoA dehydrogenases (ACAD) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACAD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. ACAD's are generally homotetramers and have an active site glutamate at a conserved position.	0
CP026649.1\|AVD54945.1\|309287_310046_+\|uroporphyrinogen-III-C-methyltransferase	gnl\|CDD\|381169	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT). SUMT is an enzyme of the cobalamin and siroheme biosynthetic pathway. It catalyzes the first of three steps leading to the formation of siroheme from uroporphyrinogen III; it transfers two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the intermediate formation of precorrin-1. Precorrin-2 is also a precursor for the biosynthesis of vitamin B12, coenzyme F430, siroheme and heme d1. This family includes proteins in which the SUMT domain is fused to other functional domains, such as to a uroporphyrinogen-III synthase domain to form bifunctional uroporphyrinogen-III methylase/uroporphyrinogen-III synthase, or to a dual function dehydrogenase-chelatase domain, as in the case of the multifunctional S-adenosyl-L-methionine (SAM)-dependent bismethyltransferase/dehydrogenase/ferrochelatase CysG, which catalyzes all three steps that transform uroporphyrinogen III into siroheme.	2.05131e-132
CP026649.1\|AVD54948.1\|311079_311706_+\|siroheme-synthase	gnl\|CDD\|180667	PRK06718, PRK06718, NAD(P)-binding protein.	8.97864e-78
CP026649.1\|AVD54941.1\|305762_307166_-\|pectate-lyase	gnl\|CDD\|378931	pfam12708, Pectate_lyase_3, Pectate lyase superfamily protein. This family of proteins possesses a beta helical structure like Pectate lyase. This family is most closely related to glycosyl hydrolase family 28.	1.03555e-14
CP026649.1\|AVD54935.1\|295579_296353_+\|gluconate-5-dehydrogenase	gnl\|CDD\|181295	PRK08213, PRK08213, gluconate 5-dehydrogenase; Provisional.	1.68568e-146
CP026649.1\|AVD54950.1\|313977_315081_-\|glycerol-dehydrogenase	gnl\|CDD\|181843	PRK09423, gldA, glycerol dehydrogenase; Provisional.	0
CP026649.1\|AVD54938.1\|299411_299816_+\|acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	2.27689e-30
CP026649.1\|AVD54936.1\|298121_298685_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|380061	pfam17932, TetR_C_24, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in family members such as HTH-type transcriptional repressor KstR2 as well as fatty acid metabolism regulator proteins. In Mycobacterium smegmatis, KstR2 is involved in involved in cholesterol catabolism, while YsiA in Bacillus subtilis is involved in fatty acid degradation.	2.82839e-38
CP026649.1\|AVD54942.1\|307335_307641_+\|hypothetical-protein	gnl\|CDD\|274982	TIGR04104, hypothetical_protein, cxxc_20_cxxc protein. This small, uncommon, poorly conserved protein is found primarily in the Firmicutes. It features are pair of CxxC motifs separated by about 20 amino acids, followed by a highly hydrophobic region of about 45 amino acids. It has no conserved gene neighborhood, and its function is unknown.	2.23646e-13
CP026649.1\|AVD54943.1\|308162_308888_+\|phosphoadenylyl-sulfate-reductase	gnl\|CDD\|129526	TIGR00434, Phosphoadenosine_phosphosulfate_reductase, phosophoadenylyl-sulfate reductase (thioredoxin). This enzyme, involved in the assimilation of inorganic sulfate, is designated cysH in Bacteria and MET16 in Saccharomyces cerevisiae. Synonyms include phosphoadenosine phosphosulfate reductase, PAPS reductase, and PAPS reductase, thioredoxin-dependent. In a reaction requiring reduced thioredoxin and NADPH, it converts 3(prime)-phosphoadenylylsulfate (PAPS) to sulfite and adenosine 3(prime),5(prime) diphosphate (PAP). A related family of plant enzymes, scoring below the trusted cutoff, differs in having a thioredoxin-like C-terminal domain, not requiring thioredoxin, and in having a preference for 5(prime)-adenylylsulfate (APS) over PAPS. [Central intermediary metabolism, Sulfur metabolism].	4.68406e-110
CP026649.1\|AVD54932.1\|292232_292952_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	7.3524e-139
CP026649.1\|AVD54949.1\|311838_312369_+\|YbaK/EbsC-family-protein	gnl\|CDD\|239825	cd04333, ProX_deacylase, This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens ProX Ala-tRNA(Pro) deacylase and also the cis-acting prolyl-tRNA synthetase-editing domain (ProRS-INS). While ProX and ProRS-INS hydrolyze misacylated Ala-tRNA(Pro), the E. coli YbaK hydrolyzes misacylated Cys-tRNA(Pro). A few CD members are N-terminal, YbaK-ProX-like domains of an uncharacterized protein with a C-terminal, predicted Fe-S protein domain.	1.43622e-74
CP026649.1\|AVD54946.1\|310052_310793_+\|sirohydrochlorin-chelatase	gnl\|CDD\|225049	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism].	5.92006e-35
CP026649.1\|AVD54940.1\|301300_302719_+\|NAD-dependent-succinate-semialdehyde-dehydrogenase	gnl\|CDD\|143421	cd07103, ALDH_F5_SSADH_GabD, Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like. Succinate-semialdehyde dehydrogenase, mitochondrial (SSADH, GabD, EC=1.2.1.24) catalyzes the NAD+-dependent oxidation of succinate semialdehyde (SSA) to succinate. This group includes the human aldehyde dehydrogenase family 5 member A1 (ALDH5A1) which is a mitochondrial homotetramer that converts SSA to succinate in the last step of 4-aminobutyric acid (GABA) catabolism. This CD also includes the Arabidopsis SSADH gene product ALDH5F1. Mutations in this gene result in the accumulation of H2O2, suggesting a role in plant defense against the environmental stress of elevated reactive oxygen species.	0

>CP026649.1|AVD54940.1|301300_302719_+|NAD-dependent-succinate-semialdehyde-dehydrogenase
MEDYLMYLNGEWTGEGLPKIKVDNPASGEVIATIPKGGEKEARLAVDAAHTAFPAWAALSAYERSAYLRTWFELIRENENELARTMTIEQGKPLKEALGEMRYANGFIEWFAEEGKRVYGETIPASTTNKRLFVHKQPVGVVAAITPWNFPAAMITRKVAPALAAGCTVVIKPAKQTPLTALKLAELAAKAGIPKGVINVITGSAKEIGDTWLADERVRKLTFTGSTEIGKELMRGSADTVKKVSLELGGHAPVIITKHADLDKAVEGTVAAKFRNAGQTCVCSNRIYVQEEVYEAFTKKFTEKVKALRVGDGLAEGTDIGPLIDRNAVEKVEHHVKDAVEKGATVETGGSAKDGLFFEPTVISNVTDDMICMNEETFGPLAPVTKFTDIDEAIRRANDSIYGLAAYVFTENISEGIQIAEGLEYGIVGLNDGLPSTPQAPFGGFKQSGLGREGGRYGIEEFLEVKYISLGL
>CP026649.1|AVD54939.1|299858_300917_+|phosphotransferase-family-protein
MHSDTIPVRKGEELDLTRLQEYLQKKFPQMPNVPLGIAQFSAGRSNLTYQLKAGSWEAVLRRPPLGPVAPKAHDMGREFRVLKALRPFFTPAPEVLLFEEDPSVIGAPFFLMERKHGIVLDTAFPPGVEPTKETCRRISGIMVDRLVELHAIPYEKTELLSMSKPDGFLERQVNGWIERYLRAKTDEIPEAEPLIHYLRDHIPPQQGAAVIHYDYKLNNAMFNEDFSEMTGLFDWEMATIGDPLADLGAALSYWTEKDDPDLIKNGLGEPSVTTLDGFMTRREFVEAYAKKSGRDVSNIDYYLIFGYFKLAGICQQIYYRYKRGQTQDQRFAHFGNVVRSLIRHAVEVAERV
>CP026649.1|AVD54938.1|299411_299816_+|acyl-CoA-thioesterase
MHELKLRTRFCETDAIGHINNTSYFIYLEDARLKFFESIGASVEIKDFNIILASVKCDFVSQAFYNEELTIRTGVAKLGNTSCELAHEILDAETGRLIARGKAVVVFFDFDKQQSRPIPDDIRGILEKHLQTAM
>CP026649.1|AVD54937.1|298837_299026_+|hypothetical-protein
MCITYSFRNEFVLSELHGMKKRITLSQLTENGLVKRRDCSSGSIMARTWKVQHPTAFAMSLY
>CP026649.1|AVD54936.1|298121_298685_+|TetR/AcrR-family-transcriptional-regulator
MKAKITEHSIRLFEQKGFTETSIQDIVDSIGATKGTFYYYFSSKEQLLMDIHMDYITKLLEKQKAILSENASCKAKLHALVLMLLESIKTEKAKALIFFREIKNLSGEKLELILQKREAFRLGVEKLIREGIEIGEFAEHLDANLTSFAILGMVNWSYQWFNPEGRKSAAEVAELFMDIVLHGIEKA
>CP026649.1|AVD54935.1|295579_296353_+|gluconate-5-dehydrogenase
MNVLELFSLKGKTAIVTGGGRGLGEQIARAFAEVGADVVLCSRKKAACEEAAARIESLGVKTLVMECDITNRAQVDEVVAETVKQFGKIDILVNNSGATWGAPAEDMPIEAWEKVISTNVTGTFHMSQAAGKVMIKQGRGKIINIASIAGLGGVDPRIMDTIGYNTSKGAVITFTKDLAAKWGRYGINVNAIAPGFFPTKMAKVIIERGKNPILEATPLGRFGNDQDLKGAAVFLASQASDYVTGDVLLVDGGMHVL
>CP026649.1|AVD54934.1|294357_295602_+|acyl-CoA-dehydrogenase
MDFDYSPKVKALISKLERFMEENVYPGEKIFEEQLNAQETRWAAVPPIMEELKAKAKQEGLWNLFLPDNEYGAGLSNLEYAPLCEIMGRSIIAPEVFNCNAPDTGNMEVLARYGSDEQKEKWLKPLLNGEIRSCFSMTEPDTASSDATNISCSIVRDGDEYIVNGRKWWSSGAGDPRCKIAIVMGKTNPDAPRHEQQSMILVPLDTPGVKIERMLPVFGYDDAPHGHAEITYENVRVPAENIIWGEGKGFAIAQGRLGPGRIHHCMRLIGAAERALELLCKRIQNRAPFGKPLAEQGVIRQWVAESRIEIEQARLLTLKAAYRMDTVGNKVARKEIAMIKAVAPRMALAVIDRTIQAFGGAGVSDDFPLARLWANARTLRLADGPDEVHLDQIARLEIKPYQERGSADERVRTV
>CP026649.1|AVD54933.1|293150_294170_+|STAS-domain-containing-protein
MSEHPNIHVGGLQFEWELEKGRFIFEGEDAVLFWIPTAMRDLFTTIEEISGEEASNVVFETAGFRQGLLVANYFNRIKDFDVKKASELITTTYASAGWGRAVMKDMNFDQKTLTIELKDSWEHKINVAQGKKTGSNFLPAHYAGIFTGLFHTNIWYKVVRYQIEGHDSTIIEYFPSDITVSHNIHQLARKKEAEQIIQLEALVEDKTRELKELIKQLSSPIIPILDGIVVVPLIGKYDDERAEELVEKTLKNLPQYKAKYLVLDLTALDVEDDPHSIQFIENIGKASSLIGTQTILVGISPSMSMTISSSGLDFSQFDCFQTLQHSIHYALGQLGRKIL
>CP026649.1|AVD54932.1|292232_292952_+|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MGRKWNNIKDKKAARDANTSRIYAKFGREIYVAAKQGVPDPVANSALKMVLERAKTYSVPKAIIDRAIEKAKGGADENYDELRYEGFGPGGSMIIVDTLTNNVNRTASEVRAAFGKNGGNMGVSGSVAYMFDKTAVFGIEGKTADEVLELLLEADIDVRDVFEEDGAVIVYAEPDQFHAVQEAFENAGITEFTVAELTMLPQNEVTLPDEDREKFEKLIDVLEDLEDVQQIYHNVNLDD
>CP026649.1|AVD54931.1|291936_292140_-|hypothetical-protein
MKKHPGWIAGIHDVPIFSSFSPVSRMIFPQFCHFSLVFGKWLVFQIRFPLIFGSALFPQAISISPVS
>CP026649.1|AVD54941.1|305762_307166_-|pectate-lyase
MIHLDKHHDPWTNGILLRQLSRRTVQPGTLIRENEALFQQYCQPEFHKPFSLSRLLLNRRYPVEPYKTLADQNGLVYPEWKTILDQAYSRLLAVASRTVNVADYGAVGDGKTDCTAAFQKALGNGRVKVIVPNGVFLVKGLKLPSWTCLCGSGKGVTIIKLHPHAPKKTRLIQNAHFHRGNHHISVEGLTLDWNVERLGQEERTAAGNNRSSCLTFAHVTFGWVKNVEAVGAGLHGFDVSSARYHYLGDGFLAPGRSRYIWLDGLTASGFGDDGITTHHSDYCFISNSFCYNPSGRAHKKGFSNSNGIEIDDGSRHVWLCNNASSGCFGGVEIKAHHNASAASHVHLYGHLSVRDNRSFNFRHIGHHKGKDADSKSANHIVAANLVSVAPVFTDLYEGSTPRSLVVSAYRNVVINGLTALGDPDYDFKGNPVVAIQYRAKNVILKNVEISGFQNAKRIRGKDKCVLL
>CP026649.1|AVD54942.1|307335_307641_+|hypothetical-protein
MSLPKCLNCNHQFKWIYIFKRLWKFDQTMECPNCTAKLYPSMKFRNKVGYLSLLCLFVSFGLMILGIPKVAFITLIVIIWVCLILTMPYVYSFDNKERPLW
>CP026649.1|AVD54943.1|308162_308888_+|phosphoadenylyl-sulfate-reductase
MEQTRLTYEQFTSDPFAAFVPEDETKGALEILQWAYGTYGKSVVYACSFGAEGMVLIDLISKVREDADIVFLDTDLHFPQTYELIEKVKKKYPALNIQMKKPSLTLDEQAAQYGSALWKRDPDQCCYIRKIKPLEETLQGAAAWISGLRREQSPTRAKTNFVNKDERFHSIKICPLIHWTWDDVWNYIRSNNLPYNELHDQGYPSIGCFPCTRAVGNSDSRAGRWAGFNKTECGLHTVQKK
>CP026649.1|AVD54944.1|309111_309291_+|hypothetical-protein
MELADKLGTNAELDPFSKLSGKSSQLFQVPACSQSRLGLFKCSHQPKQRVRLSLKQVKK
>CP026649.1|AVD54945.1|309287_310046_+|uroporphyrinogen-III-C-methyltransferase
MRKVYLVGAGPGDPELITVKGLRLIREADVILYDRLVNPDLLKEARPDAELVYCGKKPDAHTMTQDMINHLLVKFANQGKTVVRLKGGDPFIFGRGGEEAEVLVQKHIPFEIVPGITAGSAVPAYAGIPLTHRGLSTSVAFIAGVTKKGEDLDAYWSKYAGIDTLCIYMGVKNLPLICAQLIKHGKSPDMPAALIRWGTTEKQETAVSTLGNLSEKAAGLRNPSLLIIGEVVKLREELKWFEQLSAAPACTG
>CP026649.1|AVD54946.1|310052_310793_+|sirohydrochlorin-chelatase
MKQGVLYVSHGSRVPETAREATATIRQAMAQVDADLQEICYLEIAEPDIAAGIDALVRGGAGRIAVVPVLLLSAGHYYEDIPRAIREAKQRYPHIVFTYGRPLGVGDRIIEILAENILETGMPPGAWILLVGRGSRNPETLCDFAKIAAGLRAQLGTEQIKTAYLAVLEPRFDDALKELTATGHPVVVAPYLWFTGVLVRSLEKKVGMLQREGYDIRLARYLGCHPDMADALAVRAKEALGAEDFI
>CP026649.1|AVD54947.1|310835_311060_+|hypothetical-protein
MCTPDFLGRCSLKGAGVQRSLRVPALFWVRCSLKNARGPAFSIARAGTYPIPAFQETLEWEHAKQGERRAFCNG
>CP026649.1|AVD54948.1|311079_311706_+|siroheme-synthase
MVWVPVMVDLDGKQAVVIGGGKVAARRFRLLQEAGAYVTVVSPHLNDELQAMAQQRAFIWKQKTFEPEDIRQADVVIAATNDPETNSRIVAHAPAKALVNDAGHAGNGNLAFPAFFQKGRLSISVSTAGASPKLASKIANELSEHYDTNYAQYVDFLYECRQLLKRPQFSPSERSEWLEKLLGEAYRKPEKQQETLSFFHSRIQGTAR
>CP026649.1|AVD54949.1|311838_312369_+|YbaK/EbsC-family-protein
MSLEDVKAYFKQWDREEDVLVLSSSSATVELAAEALNTEPERIAKTLAFRGTGEEEALLVVTAGDAKIDNKKFRQTFGGKARMLSPEETLEHTGHAVGGVCPFGLKKDLPVYMDVSLKRFTTVFPACGSGNSAIELTCEELYTYGKAEKWVDVCKGWKTVEDYQQVAGTGVLSDPQ
>CP026649.1|AVD54950.1|313977_315081_-|glycerol-dehydrogenase
MKIPVKSVTSPKKFIVGNGLLANLYAYIKDLGDNAYVICDEFILGRAKEEAGKSVREGGGKATFEQFNYQTTQEEVDRNRRLAREAGANVIVGIGGGKTLDTAKATAYYEKLPVVIFPTIASTDAPCTALAVLYKEDGAFDRYLFLPSNPDVVLADTEILAAAPVRFFAAGIGDALATYFEARACYAANGDNLVLMKPSLTGLAIARTCYETILENGVKAVEAVKNKVPTRAVQDTIEATIYLSGVGAESGGLAAAHAIHNGMTAVPALHRAQHGEKVTFGLLAQLVLENAPKEELETVIRFIKAVGLPLTLKDLGVEEFVEAEWRKVAEDACADDDTMGNEPFPVTPEDVYNAIVAANAIAEKYHD

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Crispr_ID: CP026649_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026649_3

430615-430959

Orphan

Consensus_repeat	Method
TTTGTCCTTTTGACAGGTTCAAAAGGACATTTC	CRT

6 spacers

The CRISPR arrays of CP026649_3

>merge|CP026649|3|430615-430959|CRT
TTTGTCCTTTTGACAGGTTCAAAGGGACATTTCATTCCCGGATGCGGCATGTTTTGTCCTTTTGACAGGTTCAAAAGGACATTTCGGGCCCGGATGCAGCTCGTTTTGTCTTTTTGACGGCTTCAAAAGGACATTTCGGGCCCGGATGCAACTCCTTTTGTCCTTTTGACAGGTTCAAAAGGACATTTCGTTACCTGATGCAGCTCGTTTTGTCTTTTTGACGGCTTCAAAAGGACATTTTGGGCCCGGATGCAATTCCTTTTGTCCTTTTGACAGGTTCAAAAGGACATTTCATTCCCGGATGCGGCACGTTTTGTCCTTTTGACAGGTTCAAAAGGACATTTC

>CP026649|3|1|430615-430959|CRT
TTTGTCCTTTTGACAGGTTCAAAGGGACATTTC	ATTCCCGGATGCGGCATGT
TTTGTCCTTTTGACAGGTTCAAAAGGACATTTC	GGGCCCGGATGCAGCTCGT
TTTGTCTTTTTGACGGCTTCAAAAGGACATTTC	GGGCCCGGATGCAACTCCT
TTTGTCCTTTTGACAGGTTCAAAAGGACATTTC	GTTACCTGATGCAGCTCGT
TTTGTCTTTTTGACGGCTTCAAAAGGACATTTT	GGGCCCGGATGCAATTCCT
TTTGTCCTTTTGACAGGTTCAAAAGGACATTTC	ATTCCCGGATGCGGCACGT
TTTGTCCTTTTGACAGGTTCAAAAGGACATTTC

Protein	Signature genes	Signature genes Name	Protein_function
CP026649.1\|AVD55034.1\|425807_426281_+\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD55038.1\|434584_434770_+\|twin-arginine-translocase-TatA/TatE-family-subunit	unknown	unknown	gnl\|CDD\|237837
CP026649.1\|AVD55030.1\|422072_422777_-\|iron-sulfur-cluster-repair-di-iron-protein	unknown	unknown	gnl\|CDD\|274701
CP026649.1\|AVD55039.1\|434804_435074_+\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD55037.1\|433573_434410_-\|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl\|CDD\|234712
CP026649.1\|AVD55036.1\|431578_433399_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|372624
CP026649.1\|AVD55045.1\|439465_440173_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
CP026649.1\|AVD55029.1\|421572_422019_+\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD57787.1\|427482_428505_+\|phosphohydrolase	unknown	unknown	gnl\|CDD\|225116
CP026649.1\|AVD55031.1\|423129_423666_-\|polyisoprenoid-binding-protein	unknown	unknown	gnl\|CDD\|225228
CP026649.1\|AVD55032.1\|423732_423954_-\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD55033.1\|424545_425664_-\|NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
CP026649.1\|AVD57788.1\|429012_430395_+\|glycine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235240
CP026649.1\|AVD55035.1\|426229_427153_-\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD55028.1\|418725_419406_+\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
CP026649.1\|AVD55040.1\|435159_436185_+\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
CP026649.1\|AVD55041.1\|436497_437226_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
CP026649.1\|AVD55043.1\|437905_438721_+\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270407
CP026649.1\|AVD55042.1\|437283_437598_+\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD55044.1\|438786_439440_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836

Protein	Function_ID	Function_description	E-value
CP026649.1\|AVD55038.1\|434584_434770_+\|twin-arginine-translocase-TatA/TatE-family-subunit	gnl\|CDD\|237837	PRK14861, tatA, twin arginine translocase protein A; Provisional.	4.34295e-21
CP026649.1\|AVD55037.1\|433573_434410_-\|undecaprenyl-diphosphate-phosphatase	gnl\|CDD\|234712	PRK00281, PRK00281, undecaprenyl-diphosphate phosphatase.	6.44932e-106
CP026649.1\|AVD55044.1\|438786_439440_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.17854e-68
CP026649.1\|AVD55045.1\|439465_440173_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	4.22326e-69
CP026649.1\|AVD55030.1\|422072_422777_-\|iron-sulfur-cluster-repair-di-iron-protein	gnl\|CDD\|274701	TIGR03652, FeS_repair_RIC, iron-sulfur cluster repair di-iron protein. Members of this protein family, designated variously as YftE, NorA, DrnN, and NipC, are di-iron proteins involved in the repair of iron-sulfur clusters. Previously assigned names reflect pleiotropic effects of damage from NO or other oxidative stress when this protein is mutated. The suggested name now is RIC, for Repair of Iron Centers. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	4.44798e-94
CP026649.1\|AVD57787.1\|427482_428505_+\|phosphohydrolase	gnl\|CDD\|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	6.57407e-55
CP026649.1\|AVD55031.1\|423129_423666_-\|polyisoprenoid-binding-protein	gnl\|CDD\|225228	COG2353, COG2353, Uncharacterized conserved protein [Function unknown].	6.33719e-62
CP026649.1\|AVD55033.1\|424545_425664_-\|NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
CP026649.1\|AVD55036.1\|431578_433399_+\|amino-acid-permease	gnl\|CDD\|372624	pfam13520, AA_permease_2, Amino acid permease.	7.11674e-32
CP026649.1\|AVD57788.1\|429012_430395_+\|glycine--tRNA-ligase	gnl\|CDD\|235240	PRK04173, PRK04173, glycyl-tRNA synthetase; Provisional.	0
CP026649.1\|AVD55041.1\|436497_437226_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	5.70829e-167
CP026649.1\|AVD55028.1\|418725_419406_+\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	4.65303e-44
CP026649.1\|AVD55040.1\|435159_436185_+\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	1.99787e-41
CP026649.1\|AVD55043.1\|437905_438721_+\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270407	cd13689, PBP2_BsGlnH, Substrate binding domain of ABC glutamine transporter from Bacillus subtilis; the type 2 periplasmic-bindig protein fold. This group includes periplasmic glutamine-binding domain GlnP from Bacillus subtilis and its related proteins. The GlnP domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.70304e-93

>CP026649.1|AVD57788.1|429012_430395_+|glycine--tRNA-ligase
MSVTMDQIVSHAKHRGFIFPGSEIYGGLANTWDYGPLGVEFKNNVKKAWWKKFIQESPYNVGLDAAILMNPRTWEASGHLGNFNDPMIDCKHCKARHRADKLIENALHEKGIDMIVDGLPFEKMEALIKEHDIACPDCGSKDWTGIRQFNLMFKTYQGVTEDSTNELYLRPETAQGIFVNFKNVQRTMRKKLPFGIAQIGKSFRNEITPGNFIFRTREFEQMELEFFCRPGEELKWFDYWKQYAREFLLNLGMREENLRLRDHEKEELSHYSNATTDFEYNFPFGWGELWGIASRTDYDLKRHMEYSGEDFTYLDQETNERFVPYCIEPSLGADRVALAFLIDSYAEETLEDGTSRTVMHLHPALAPYKAAVLPLSKKLSDEARDIFADLSKTFMVDFDETGSIGKRYRRQDEIGTPFCITYDFDSRDDHMVTVRDRDTMEQTRVPITELKAFLEEKIEF
>CP026649.1|AVD57787.1|427482_428505_+|phosphohydrolase
MVFQKGEKLEEDLYSNSGVLLLRKGTFLTERLAAILNKYEVLRDPELDGRRIATDVPGIFHDLLYENIYHEMEELQRIIQVKTTLCDAEVESMEKNFRKLYKEVFTTRTSILELMEHFSADEYLFKHCIHVGLIAANIGKILKLDPEKQSLLAQMGLFHDIGKFTIDPQILNKPGRLTDEEFALIKKHPEAGYRLLEKTSLDPMILKGTLMHHERLDGSGYPDGRKTIPFLVRILSVADTFDAICSNRAYRRRQPVFFAIDELMADADAGRLDREIVLPFANFLMENYRKQPITLRNGVKGSIIRIHPLHPNQPVLKVEGYPVLNLMEQKLTLFQIANPY
>CP026649.1|AVD55035.1|426229_427153_-|hypothetical-protein
MLDIQFFQLPAALSVSENRPLPRNFRDKRASALLYLDSRIYFSFPVTLPVSEKDCSHAFSATNEYHLCFAWISVSISVFRRTSEYRLLFWCGFPVLESILSGQTSGFAWLLDIQFFQLPTALSVSENRPLPRNFRDKRASALLYLDSRIYFSFPVTLPVSEKDCSHAFSATNEYHLCFAWISVSISVFRRTSEYRLLFWCGFPVLESILSGQTSGFAWLLDIQFFQLPAALSVSENRPLPRNFRDKWASALLGFPYLFQLSSRTSCFGKRLLPSNFTQQMGIGFVWIPFLFQLSAALSCFRKWMTSA
>CP026649.1|AVD55034.1|425807_426281_+|hypothetical-protein
MSDVLLLLQMVAKRLSILSLITAVLLLLSHLWLYAVFAFIIMGGLICVDRIISEKGNSRAAENRRYYTLIVVTDEDWYEEEHVPFLEMDHVSLELHYQYEDIRRINPLIQLQAFPGFVLVETDDTKRIEESLQNPALVTGNYAEVIHFLKQESAAES
>CP026649.1|AVD55033.1|424545_425664_-|NADH-dependent-flavin-oxidoreductase
MSKYDKLFEPITFKSGVRAENRIVMAPMTHYSSNDDGTISDAELRYYAERAKGPGMVVTACANVTENGKAFTGQPGAHTDEMVESMKKLAQTIQQNGAKAVVQIHHGGRECPAELVPGGDVVSASETDSSDGSVHARALTGEETAEIVKAFGEATRRVIEAGFDGVEIHGANGYLIQQFFSPYTNWREDEWGGSLEKRLAFPLAVVDAVKKTVAEYADRPFLVGYRLSPEEPYEPGITMDDTFALLDALMEKELDYVHISLQHFWSKARRGGEPGRPRMEQIVEHVAGRVPLIGVGSLHTGDEVLKAMETDVPLIALGRELVMEPHWVEKIKAGQEDAIQTALRKDDRERLVIPEPLWKMIISTPGWFPFAE
>CP026649.1|AVD55032.1|423732_423954_-|hypothetical-protein
MTRIAAGFQHAAFARLTACPNWFPQTPLTMQDSAWCKNHYTAKESAKSTINMQDVAYLLIQKPNPFKKRVRFS
>CP026649.1|AVD55031.1|423129_423666_-|polyisoprenoid-binding-protein
MTKTKWAVDYAHSTIDFTVKHMMISKVKGSFQNFEAEIEADPQDLTDAKVSFIVDARSIHTKNDDRDNHLRSADFLDVEQYPNITFVSKSVTKAGDNDYNVTGDLTIHGVTKEETFKVTFEGISKNPMSGAETAGFSAEGTVKRSNYGLTWNAALETGGVLVGDEIKFTVELEASKAE
>CP026649.1|AVD55030.1|422072_422777_-|iron-sulfur-cluster-repair-di-iron-protein
MERFTTSQTVGEIVTLFPKAADLFKANRIDFCCGGNVSVKEAAEKRNLSADELLDAICNLYGQYAGKGTEQNWNEAGYTEIVNYIQATHHAFLREELPNLSPYVTKVMRVHGGNHPHLIEVHELFNQLKAELLEHTEKEDTEQFPAIRAYENLPTAANLKAATAGLTDLETEHAAVGEILHRLREITNDYTLPEGACRTFQLVYHRLENFENDTFQHIHLENNILFKRLLEEAV
>CP026649.1|AVD55029.1|421572_422019_+|hypothetical-protein
MVPGASKRQKRAGIRANCPFGGLKKTKESRTRGKLSFWRSQKDKRKPDPGQIVLLKVSKRQKRAGIRTNCPFEGLKKTKESWNPGKLSFWRFQKDKRKPDPGQIVLLGGSKRQKRAGIRANCSFGGLKTTKEERTRNELSFPGARKEK
>CP026649.1|AVD55028.1|418725_419406_+|Crp/Fnr-family-transcriptional-regulator
MENLRKMPLFKGLGDADLAVIADISVKKHAEKDAHIFFQGDPQEAVYFIESGEVKIYRTDANGKEQVVTLLRDGDMFPHVGFFRKISYPANAMAVVDTNLVAIRITDFENVLLNNPQLTMTLYGVMSDEILDLQDRLEAQILNNAYEQVVKLFLRLTRTHGVQEKDGFVLVKTPLNNSDLANMIGVTRETVSRTIRQLKEKNLILPQEKGTYLIHQEKLTEELLGV
>CP026649.1|AVD55036.1|431578_433399_+|amino-acid-permease
MFTTIKRLLIGRPLRSNELEGQKLTKLKALAILSSDALSSVAYGPEQVLIVLATVGTLAFWYSIPITVGILILLAALILSYRQVIYSYPQGGGAYLVSKENLGVTPGLLAGGSLLVDYILTVAVSVSAGTDAITSAFQSLHPYSVQIAVFLVLIITILNLRGLTESANVLAYPVYLFVFALIVIIVVGLFKTVTGQVPQNLHPHIGTPVAGISLFLLLKAFSSGCSALTGVEAISNAIPNFRDPAPRNAARTLAMMGIILASLLAGISFLAYWLGIAPKETETVVSQMAHRALGNGVLYYFVQATTALILVLAANTGFSAFPQLAFNLARDKFMPRMFTIRGDRLGYSNGIIFLGAASMILIVAFQGNTERLIPLYAVGVFIPFTLAQCGMIVKWVTQRPRGWAGKMSVNFVGAIITFSVLAILFITKFMQVWPVLIFLPIVMFIFRKVNRHYEAVGEQLRIKGVFQEEIHSNVIIVPVAGITTVVERTINYAKSLSDQVIAVYVAFDHEDEKRMEEKWKEWDCGVRLVTLHSSYRSIVQPLAKFLEIIQRKAKENKYQVMVLIPQFIPKKRWQNILHNQSALLIRMRPLWEKDVVVATMPYHFKK
>CP026649.1|AVD55037.1|433573_434410_-|undecaprenyl-diphosphate-phosphatase
MHLWNLFVAAILGLVEGLTEFAPVSSTGHMIIVDDLILKSNHLYGTEAANVFKVVIQLGSIMAMVVVFWDRFLNLLGLKKNITREQMYGERLRLTHVITGLVPAAVLGFLFEDYIDAHLFSVNTVLVALVVGAILMIVADLTRPRRPKTETVDQITYRQAFVVGLFQCLALWPGFSRSGSTISGGVLLGMSHRAAADFTFIMAVPIMFGASFLSLVKHWGAVTPETIPFFITGFISAFIFALIAIKFFLALINKVKLVPFAIYRILLAIVLLLLIWNR
>CP026649.1|AVD55038.1|434584_434770_+|twin-arginine-translocase-TatA/TatE-family-subunit
MPGNLSFGEVLIILVVALLIFGPSKLPQLGRAAGQTLREFKKGVRDAIDEEEKPQVKKSKS
>CP026649.1|AVD55039.1|434804_435074_+|hypothetical-protein
MHAPRHFPNAFHGKTPKDDRPDTFTGRKCSRNALSPGTDSIFLIVIDFDAKNLSSFYIAAGTEGSPWADSSVWFISFYGRKKFYTSLAG
>CP026649.1|AVD55040.1|435159_436185_+|AI-2E-family-transporter
MEDRLFSLFQKRGVRRVLIFVLITLILYFLRSMMDLMLLTFIFSYLVNRLQKIVTRWFPIKRRLAVLIVYILILGGLILGVIKYFPILVNEITQLVMQISDFYTKPQHNEVLNYIVKNIQEKKIVDYAQKGVSILFDYFTSISKVSIQVFMAIILSLFFLLEKERIIRFTKQFKKSKLAAFYDEIEYFGVKFVGTFGKVIEAQFIIAVVNSVLTTIGLWILGFPQLFGLAILIFALGLIPVAGVFISLIPLCIIAYSIGGGMKVLYVLILIVIVHAVEAYVLNPQLMSSKTNMPVFYTFLILIFCEHFFGLWGLILGIPIVMFFLDVLEVTGQSTEPKKKT
>CP026649.1|AVD55041.1|436497_437226_+|amino-acid-ABC-transporter-ATP-binding-protein
MISFRHVNKYYGDFHVLKDINLEVKEGEVVVVIGPSGSGKSTMLRCINRLEDITDGELFVRNMKVNDKKTDINDLRKNIGMVFQHFNLYPHRTVLQNITLAPIKVLGQSKEEAEKKAMHYLERVGIPDKANAYPSQLSGGQQQRVAIARGLAMEPDIMLFDEPTSALDPEMIGEVLDVMKALAKDGMTMVVVTHEMGFAREVADRVLFMDQGRIIEDNTPEDFFKNPREERARTFLNRVLNH
>CP026649.1|AVD55042.1|437283_437598_+|hypothetical-protein
MEANDRGYWVHACRPSIAGKPATNGGQTSCITPGQDAKNRVQTIRGYQVHTWRHQSPESRLRWRPNTLHHARAGCQKSEANDPRLSGARMAASLPESRFLVAAK
>CP026649.1|AVD55043.1|437905_438721_+|amino-acid-ABC-transporter-substrate-binding-protein
MGKVKKWLAAGLVFILAAALVAGCGKSKSTGGSGSASDDPIKKIEDRGKLVVGVKYDTYLFGYKDPKTGNVEGFDVDIAKAISKKIFGDKVKVELKEVTSKTRIPMLQNGDVDMVVATMTISPDRKKVVDFSDVYFDAGQSLLVKKGSKIKSVKDLTKGTKVLTVKGATSGDNVRKAAPDTTVLEYENYQEAFTALKSGKGDALTTDNSILYGMAAQDSNYQVVGGTFTKEPYGIAMKKGNTKLVKAVNKALKELKDSGEYDKIKNKWIKE
>CP026649.1|AVD55044.1|438786_439440_+|amino-acid-ABC-transporter-permease
MLDFSILTDNIDLYMKGFVNTIKISIIGLVASFILGNLIAVFRLAPVKLLNFIGAVYVEVIRNIPLILTGFFFYNGLSYFHINLSGFIAGTIALSIYTAAFIAEAVRAGIQSVDKGQLEAARSTGLTYTQAMRYVVLPQAIKIVIPPIGNQFLNLVKNSSILGVFAGLDLMYYADLIHEKTWITFDTYIFVGMFYLILTIPLSLLVNYLERRLARSS
>CP026649.1|AVD55045.1|439465_440173_+|amino-acid-ABC-transporter-permease
MDFAGAYSSGNLAYLLKGFAVTLEVAFVAIVLSFLIGCILGILRYAKIPILSPIVALVVEITRNLPLILIIFFTYFALPEVGMKMSVTAAAISALTVFESAMIAEIVRGGLNAIPKGQIEAARSSGLKYIQTLWYIILPQALKKMIPPLVSQFISLLKDTSLAIIIALPELLHNAKGIYNGEGGSKYIIPILLMAAFMYFVVNYLLSILARRLEKRLDPDRSAAKQLVNTTENLL

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Crispr_ID: CP026649_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026649_4

574894-575854

TypeI

Consensus_repeat	Method
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	CRISPRCasFinder
GTCACACTCCTCGTGAGTGTGTGAATTGAAATN	CRT

14 spacers

cas7,cas8c,cas5

The CRISPR arrays of CP026649_4

>merge|CP026649|4|574894-575854|CRISPRCasFinder,CRT
GTCACACTCCTCGTGAGTGTGTGAATTGAAATCTTCATGTATCCCGGCACGATATAATAATCATCGTGTCACACTCCTCGTGAGTGTGTGAATTGAAATTCGATAGCCTTTAACGTGATAAAATCGTTTTTCAGCGTCACACTCCTCGTGAGTGTGTGAATTGAAATACAGAACTTTATTGTGAGGTGAAGGCCGGTGGCGTCACACTCCTCGTGAGTGTGTGAATTGAAATCAATAAGTTGATGATCGGGATCACAACGGCCGGCGTCACACTCTCGTGAGTGTGTGAATTGAAATATCACAAATGCTTCTCTCTCGCGCGGAGACAGCCGTCACACTCCTCGTGAGTGTGTGAATTGAAATCGGGGTTGGGACAGGCGGCCGGTCCGTTACACTTAGTCACACTCCTCGTGAGTGTGTGAATTGAAATGCAGCCATTAGGCGCTGTGCTTTCACGGTATTTGGTCACACTCCTCGTGAGTGTGTGAATTGAAATATAAAAGTTACGTATGGTATCGTCAATCTACATCGTCACACTCCTCGTGAGTGTGTGAATTGAAATCCGTTAACGTTGACGACTTTGACGCCTTTTATCAGTCACACTCCTCGTGAGTGTGTGAATTGAAATCAGCCGTTCGTATATTTTCCGGCAGACCACGCCATGTCACACTCCTCGTGAGTGTGTGAATTGAAATGAAAGTTGTCGGGTCTGCAAAGCTGATGCCGATAGTCACACTCCTCGTGAGTGTGTGAATTGAAATAGTATCTCCAATATAACATGAAACGAAGTCAGAAAGTCACACTCCTCGTGAGTGTGTGAATTGAAATCCGATTTTAGGCCCCGCTCCGACAACGTATAGTGCGTCACACTCCTCGTGAGTGTGGGGATTGAAATCAAACGGGTTATCGGTAAAATGGCTGACGGCGGCGTCACACTCCTCATGAGTGTAGAAATTGAAAA

>CP026649|4|2|574894-575854|CRISPRCasFinder
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	CTTCATGTATCCCGGCACGATATAATAATCATCGT
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	TCGATAGCCTTTAACGTGATAAAATCGTTTTTCAGC
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	ACAGAACTTTATTGTGAGGTGAAGGCCGGTGGC
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	CAATAAGTTGATGATCGGGATCACAACGGCCGG
CGTCACACTCTCGTGAGTGTGTGAATTGAAAT	ATCACAAATGCTTCTCTCTCGCGCGGAGACAGCC
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	CGGGGTTGGGACAGGCGGCCGGTCCGTTACACTTA
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	GCAGCCATTAGGCGCTGTGCTTTCACGGTATTTG
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	ATAAAAGTTACGTATGGTATCGTCAATCTACATC
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	CCGTTAACGTTGACGACTTTGACGCCTTTTATCA
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	CAGCCGTTCGTATATTTTCCGGCAGACCACGCCAT
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	GAAAGTTGTCGGGTCTGCAAAGCTGATGCCGATA
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	AGTATCTCCAATATAACATGAAACGAAGTCAGAAA
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	CCGATTTTAGGCCCCGCTCCGACAACGTATAGTGC
GTCACACTCCTCGTGAGTGTGGGGATTGAAAT	CAAACGGGTTATCGGTAAAATGGCTGACGGCGGC
GTCACACTCCTCATGAGTGTAGAAATTGAAAA

>CP026649|4|2|574894-575854|CRT
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	CTTCATGTATCCCGGCACGATATAATAATCATCGT
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	TCGATAGCCTTTAACGTGATAAAATCGTTTTTCAGC
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	ACAGAACTTTATTGTGAGGTGAAGGCCGGTGGC
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	CAATAAGTTGATGATCGGGATCACAACGGCCGGC
GTCACACTCTCGTGAGTGTGTGAATTGAAATA	TCACAAATGCTTCTCTCTCGCGCGGAGACAGCC
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	CGGGGTTGGGACAGGCGGCCGGTCCGTTACACTTA
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	GCAGCCATTAGGCGCTGTGCTTTCACGGTATTTG
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	ATAAAAGTTACGTATGGTATCGTCAATCTACATC
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	CCGTTAACGTTGACGACTTTGACGCCTTTTATCA
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	CAGCCGTTCGTATATTTTCCGGCAGACCACGCCAT
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	GAAAGTTGTCGGGTCTGCAAAGCTGATGCCGATA
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	AGTATCTCCAATATAACATGAAACGAAGTCAGAAA
GTCACACTCCTCGTGAGTGTGTGAATTGAAAT	CCGATTTTAGGCCCCGCTCCGACAACGTATAGTGC
GTCACACTCCTCGTGAGTGTGGGGATTGAAAT	CAAACGGGTTATCGGTAAAATGGCTGACGGCGGC
GTCACACTCCTCATGAGTGTAGAAATTGAAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP026649.1\|AVD55142.1\|576182_576701_-\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD55136.1\|566840_568172_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|225212
CP026649.1\|AVD55134.1\|564457_565441_-\|2-nitropropane-dioxygenase	unknown	unknown	gnl\|CDD\|240081
CP026649.1\|AVD55141.1\|573596_574520_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|377458
CP026649.1\|AVD55149.1\|587066_588278_-\|butyryl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173847
CP026649.1\|AVD57797.1\|586500_586824_+\|DUF3870-domain-containing-protein	unknown	unknown	gnl\|CDD\|372419
CP026649.1\|AVD55133.1\|562710_564288_+\|hydantoinase-subunit-beta	unknown	unknown	gnl\|CDD\|223223
CP026649.1\|AVD55144.1\|579180_581397_-\|peptidase	unknown	unknown	gnl\|CDD\|375438
CP026649.1\|AVD55146.1\|583355_583721_+\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD55147.1\|583849_584767_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381318
CP026649.1\|AVD55143.1\|577392_579048_+\|amino-acid:proton-symporter	unknown	unknown	gnl\|CDD\|223605
CP026649.1\|AVD55135.1\|565443_565800_-\|cysteine-methyltransferase	unknown	unknown	gnl\|CDD\|377256
CP026649.1\|AVD55138.1\|568392_568608_+\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD55148.1\|585898_586126_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273806
CP026649.1\|AVD55140.1\|571916_573593_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|378245
CP026649.1\|AVD55139.1\|571268_571916_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09651_cas5_CAS-I-C	gnl\|CDD\|187782
CP026649.1\|AVD55145.1\|581874_582843_+\|LytR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224235
CP026649.1\|AVD55137.1\|568187_568400_+\|DUF3006-domain-containing-protein	unknown	unknown	gnl\|CDD\|378598
CP026649.1\|AVD57796.1\|584963_585902_+\|transposase	unknown	unknown	gnl\|CDD\|273806
CP026649.1\|AVD55132.1\|561616_562711_+\|DUF917-domain-containing-protein	unknown	unknown	gnl\|CDD\|377590

Protein	Function_ID	Function_description	E-value
CP026649.1\|AVD55136.1\|566840_568172_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	2.62121e-81
CP026649.1\|AVD55134.1\|564457_565441_-\|2-nitropropane-dioxygenase	gnl\|CDD\|240081	cd04730, NPD_like, 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase family that reduce a range of alternative electron acceptors. Most use FAD/FMN as a cofactor and NAD(P)H as electron donor. Some contain 4Fe-4S cluster to transfer electron from FAD to FMN.	3.85955e-97
CP026649.1\|AVD55141.1\|573596_574520_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	5.24635e-125
CP026649.1\|AVD55149.1\|587066_588278_-\|butyryl-CoA-dehydrogenase	gnl\|CDD\|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	1.16473e-162
CP026649.1\|AVD57797.1\|586500_586824_+\|DUF3870-domain-containing-protein	gnl\|CDD\|372419	pfam12986, DUF3870, Domain of unknown function (DUF3870). A family based on the C-terminal domain of 3KOG which shows structural similarity to pore-forming proteins, suggesting it may have a lytic function.	7.31509e-39
CP026649.1\|AVD55133.1\|562710_564288_+\|hydantoinase-subunit-beta	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	4.26122e-95
CP026649.1\|AVD55144.1\|579180_581397_-\|peptidase	gnl\|CDD\|375438	pfam17936, Big_6, Bacterial Ig domain. This domain is found in a wide variety of extracellular bacterial proteins often in multiple tandem copies.	4.3433e-12
CP026649.1\|AVD55147.1\|583849_584767_-\|aldo/keto-reductase	gnl\|CDD\|381318	cd19092, AKR_BsYcsN_EcYdhF-like, Bacillus subtilis YcsN, Escherichia coli YdhF and similar proteins. Bacillus subtilis YcsN and Escherichia coli YdhF are prototypes of this family. They are uncharacterized aldo/keto reductase family oxidoreductases.	3.79414e-145
CP026649.1\|AVD55140.1\|571916_573593_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	6.86893e-119
CP026649.1\|AVD55135.1\|565443_565800_-\|cysteine-methyltransferase	gnl\|CDD\|377256	pfam04237, YjbR, YjbR. YjbR has a CyaY-like fold.	8.61755e-27
CP026649.1\|AVD55148.1\|585898_586126_+\|hypothetical-protein	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	0.00643442
CP026649.1\|AVD55143.1\|577392_579048_+\|amino-acid:proton-symporter	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	6.75615e-60
CP026649.1\|AVD55139.1\|571268_571916_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	3.04765e-79
CP026649.1\|AVD55145.1\|581874_582843_+\|LytR-family-transcriptional-regulator	gnl\|CDD\|224235	COG1316, LytR, Transcriptional regulator [Transcription].	8.4844e-44
CP026649.1\|AVD55137.1\|568187_568400_+\|DUF3006-domain-containing-protein	gnl\|CDD\|378598	pfam11213, DUF3006, Protein of unknown function (DUF3006). This family of proteins has no known function.	2.18383e-20
CP026649.1\|AVD57796.1\|584963_585902_+\|transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	2.11792e-11
CP026649.1\|AVD55132.1\|561616_562711_+\|DUF917-domain-containing-protein	gnl\|CDD\|377590	pfam06032, DUF917, Protein of unknown function (DUF917). This family consists of hypothetical bacterial and archaeal proteins of unknown function.	0

>CP026649.1|AVD55141.1|573596_574520_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MNINSIIDPNKRYDFVLVFDVTDGNPNGDPDAGNLPRIDPETMQGIVTDVAIKRKIRDYIYLTRGHLEGFDIYVKHRGILTKEQKKAYEQLEKQENDDSPKTVKDARQWMCEHYFDTRMFGAVMSTKKFNAGQVRGAVQLTFARSVDPIFPAESSITRVALTNADDIKSGKATDEEARTGQMGRKAYVPYGLYIAYGFYTPSFAVQTGVREEDLKGLWESLINMWDLDHSASRGRMACRGLYVFSHESYLGNAPSNQLFEKIEIHRIDQHKVARSYKDYAVVFDEKMPEGVTLHKIANSFKDAKVVN
>CP026649.1|AVD55140.1|571916_573593_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MYMRRLVEFAEQHANDLPPVGYARRSYQWFVVITHDDRFEFIQADRGEQRVIPNRSRASGVSPILLTDKAEYVFKLPKNPANAKRAAECHLAYMKLLKECCEATRNELVQKIVQILERQDWQIPDGMKSTDVILFRTEAGDFPHEDNKVKKFWEDFLIKNSSKEENDSVCFICGCSAPAVKRHTIEFSVGKERTKLISANESAYLSYGLENSEIAPTCFECEQKYGQALSYLLRKYANKKQHGGPHMMEIGNVTYVYWARQNDPETTSMFTFLSDPDPVAVRRILSSPFKRAENHGSLDRICILALSANKARMVVRDYAEPPVWKVKNQIRQFFYAQQIVGAPKPASIYLLAACMYRDGRKEMQKEDVQDWMNWAIYGKRLSGRIIAKMVKRIQARGGMAWIHAAAIKSWLISQKKEEWTVDLDQARVTPAYLCGRLFAVLEAVQYEAVKGNETIASRFYAAASSTPRTIFGLLMRNSKWHLSKISKENKGYEVRYQQRIQLITGQLKEFPAVLDLQGQAEFALGYYHERQDIYKKKENMSADAANVSDFNNTVVEGE
>CP026649.1|AVD55139.1|571268_571916_+|type-I-C-CRISPR-associated-protein-Cas5
MGKIFRLKVWGEYALFTRVEAKVERVSYPVMTPSAARGILTGIFWKPEFKWRIKSIHVLKPIQYYSILRNEVASIVPSNIVTSKRDYFTDDDRQLRHSIMLRDVAYIITAEMHLMNPTMENKRKYASMFLRRVAKGQCFYRPYLGTRECSLHFSLPEDDDQAIPDTMDIGPMLFDLKYPADPGQKNARAIPYFFNAKLDRGILHVPEYLYKEVDG
>CP026649.1|AVD55138.1|568392_568608_+|hypothetical-protein
MSRQQGGRIYRDADWAYSYIQIGFVLPNFYNKEVHGNLCVPLRGIIALYHIFKNKIKMEGEYRCFEIFNHL
>CP026649.1|AVD55137.1|568187_568400_+|DUF3006-domain-containing-protein
MKYIVDRIEGEFAVCEKDDRTTVDIRLSELPSGVQAGDVIIVEDGIPRIDRQLTKERKAQIKKLADELFE
>CP026649.1|AVD55136.1|566840_568172_+|MBL-fold-metallo-hydrolase
MKINRTGAWFLLLFFMLFCSGCGQTQPANSQPAKEKQVQQVSTEKSESKADSKTVNKTDSHHKSTASLPKGKLKVYFFDVGQGDSILIQTPKGENVLIDGGNNDKGDDVVRYLRQLHVSQLDDVIATHPDADHIGGLDTVLENLKVKNVYAPRVVNTTRTYEDFLLAVKNSRLKIKQAKANVDLGLQGASMKFAAPVKDYHEEMNDWSAVAKLSYGEKGTFLFTGDAPFRSEEDMIATHQDLSSQVLKVGHHGSKTATSQAFLDAVKPKYAIISVAKVNSYGLPSDEVINRLKANHIQIFRTDEMKTILAVTDGHSIEFQPVPSLTPNHLSSEAGNATASGKAVPPAKQPSQRTTSNGTLQAKVDDQTPQQYGKINLMVTGLTGAAYQATFHYKSKDTVYQGTAGTPLPVRISRAAPGYEVRIDIKAVVKGKTYTTHTSFTPQ
>CP026649.1|AVD55135.1|565443_565800_-|cysteine-methyltransferase
MKTREDAIHYCLKLENTYEDYPFKDKNWTLMRHKKNKKVFAWIFERNGHIWINVKGENGWLDFYRRKYHAVVPAYHLNKEHWNSVILDGTVPEEEICDMIRQSYHLTKKKGIQSNRSR
>CP026649.1|AVD55134.1|564457_565441_-|2-nitropropane-dioxygenase
MRTRITEILKIKYPIIQGGLAYLGYAELAAAVSNAGGLGQITAATLRTPEKLRNAIHKVRKLTGKPFGVNFAIARYNGRYEELLEVAIEEKVPAISISGGNPQPVFERIKGENIRTLVLVAGTRQAQKAEQLGADAVIAVGQEGGGHLGRDDIGGMVLIPRVADEVSVPVIAGGGIGDGRGLLAALALGAEGIQMGTRFIATKECIHAHEKYQQTIVHAKETDTVVIKRTLGAPGRVLKNRFALNIMEREQEGASYEGLKEMISGSANCNYIYDGNEEKGYAWAGQVVGLIHTIPTVQELFDEMMHTAEKGLSRLDHIMKEQTHRSS
>CP026649.1|AVD55133.1|562710_564288_+|hydantoinase-subunit-beta
MGVYRVGIDVGGTHTDAVLLDEKNAVIAETKSPTTEDVATGIYHAMHKIISDANVPRDQIQYAMLGTTHCTNAIVERKRLNNIAVVRIGAPATLAVKPLIGVPEDLREALGKHVYLVRGGHEFDGREITALDTDHLFQIAREMEGKVDSIAITSVFSPVSQGHEHRASEIFREVLGDGVAISLSSEIGSVGLLERENATILNAAVVNVAKTAAEGFIQALKNEGIKAHVFFGQNDGTLMSVDYAVKYPIFTVACGPTNSLRGASYLSQLSDAIVVDVGGTTSDAGVLVNSFPRESSLAVEIGGARTNFRMPDLISIGLGGGTIVRIRDSGEFTIGPDSVGYRLPEKGLVFGGDTLTTTDVAVALGKVELGDPEKVAHLDKKVMQQVYGRMVEMVEEAIDKMKTSAAPVPVILVGGGSVLLPDSLKGASRVIRPEHSGVANAIGSAIAQVSGQIEKIYVLDEIGREQALESAKSQAKQEAIKAGADPGSLVIVDIEDVPLAYLPGNATRIRVKAAGELGRMPVASI
>CP026649.1|AVD55132.1|561616_562711_+|DUF917-domain-containing-protein
MRKIGIQEIEDIAVGAALLGTGGGGDPYIGKLMAIQAIEEYGEVTLLDAEEVPDDALVVPSSMMGAPTVMLEKAPSGEEAFVAFQKLETYLGDKIYATFPIEAGGVNSMLPFALAAKLGLPVVDADGMGRAFPELQMVTFYLDGIAATPAVLADEKGNTVVLSTIDNVWTERIARAATVQMGGSAMTAMYAMKGRNLKESGVRNILKLEETIGKTIRKAKENNANPIREVVKSVKGFPLFSGKVKDINRKTESGFARGTATFEGMHENKGETLTLRFQNEHLLARTEERLLCMTPDLIAVLDAETGLPITTEGIRYGARCVVIGIPCHPKWRTEKGLATVGPKYFGYDADYVPVEELAKEGVRS
>CP026649.1|AVD55142.1|576182_576701_-|hypothetical-protein
MQITVAEARLLKNAVSKKLHDLIQERNQIAYVEFEKGEKYTPHARTFQEVGTEIHQVRNHYRAVTKALAASNLRTTIEWKGEKISIVEALELVKQLRAEAEMLQEFGNSQQVERIARGAFDANVVYKKALFDPPAVKKQAEKTEKEANRLSILIDKANFNAAVDLDFVEEYQ
>CP026649.1|AVD55143.1|577392_579048_+|amino-acid:proton-symporter
MNKMHRKLGTFALTMTGLGSIIGSGWLFGAWKAATIAGPAAIFAWVIGMVVILFIALSYSELGAMFPVAGGMVKYTQYSHGSFVGFLAAWANWIAIVSVIPSEAMASVQYMSSWHWSWAHSLAHNGMLTPKGLGLASLLLLIYFFLNYWAVSLFARVNSLITIFKIIIPGLTIFALLIVGFHGSNFTYGQAFAPYGWSSVLTAVATSGIVFAFNGFQSPINMAGEARKPGRSIPIAVVGSVLIATVIYVLLQIAFIGGVSPSVLAHGWNHLNFNSPFADLAIALNINWLVIVLYLDAFVSPSGTGTTYTATTARMLYGMEKNGYLPRFIGKLHPVYGIPRPAMFVNLVICFIFLFVFKGWGSLAEVISVATLISYITGPVTVMALRKTAGYLYRPLQVKGMQIIAPCGFIFASLTLYWARWPLTGEVFLIIMIGLPIYFYYQAKRKWQSFSKNFKSGIWMVAYLIVMMGISYFGSEKFGGLNMIPYGWDMVLIAFVSLGFYIWAVKSGYETPDLLEAAKLNKALKEHDMGVDDDENGNGKRNPAYSTDWPH
>CP026649.1|AVD55144.1|579180_581397_-|peptidase
MKVIKKTIYLVLAIALILPALVLQTGHASASTTQTLNFNTTVTNTISNKNAEQVYKITLPSAGTVKVNLNSYIEAVILDLTDENGKSVWGYSRDIYDGSASTPKQWSDQADLEAGIYYIKISQSSDYTGKYDLKVGFNTAGNNETEPNNGTSQAQPITLNTQKINGFLSLNDDTDCYKFILKQAGTIDVHVDSNIYDASLDLLDESGNDVWGIDEDIYGGSSQTPKQWSKSVDLEAGTYYIKISNSSGYTGKYNLYVNYTPAGNNEVEPNNGTSQAQELSNGQKVTGFLSWSDDTDVYKVNLPKAGNLKISLDSSIDWAYVDLIDANGNNIWDEESVYDGTKETPKQWMKDADLEAGTYYIKIHSPETGTYHLSTWFTAAGNNESEPNNGTTQAQQISLNTQKITGFLSESDHTDCYKFTLPKAVKVTMNVDSSMKGVDLHLTNSKGTALWDDYIYDGSIETPKQWNKSESLPAGTYYLKISSDYNTGKYVLSVNAPLYPSAPSINTVSTNSTSVSGKTDANCTVYVKAGSKTYKGKSNNKGDYKVSIPKQKAGTKIYVYATNTYGKSGTKVTTVGSPAATPSVNTVSNKSTFVSGKTSKSSTVHVKIGSKTYKGKSNSKGDYKVSIPKQKAGTKIYVYATNTYGKSGTKSVTVVDRIAPSTPSVNTVSHTSRYITGKTEAYATVTAYTGSKKIGSAKADKHGSYKIKISPKKKGTAVKVKATDKSGNSSGYRTVKVK
>CP026649.1|AVD55145.1|581874_582843_+|LytR-family-transcriptional-regulator
MKKLRIFLSILLAVVVLGGGVAYFAYQKLQPENHFKNVPTVSKTGNNPGSQGTTTPKMKENVFNVLLLGSDERKGQKVGHSDSIILLHVDLNKHKYNMASIPRDTRVYLDGYGYTKLTSVQYIKQATGGTTAGIKAAVNSISQLTGVPVNYYVETNYEGLQSMVDALGTIDVDVPFDVKLTHPWYPENKGRIIAQGTQTLDGEMVTELVHERYSLKNVDYDRQLLQAKVLIGIAKTALQPKNLTKLPKLVDKSSDFVIATNMSKTDIASLGLLVKNLNTDKQVTYYQLKGTSKSMYDDILKNNNSEIVLDQTALKKTMKHFE
>CP026649.1|AVD55146.1|583355_583721_+|hypothetical-protein
MATILYAVFIAIALYVLNGMAFMKLAQKAGRGDIAWMAWVPVCNVIQQLLLIKKSGWWVLILLVPVVNFIFIIIWQVKLLQAFGKHGAYVLLYIFIPIVYQILWIVWAFSDETEYVEREAV
>CP026649.1|AVD55147.1|583849_584767_-|aldo/keto-reductase
MNHINLGKSGILGSEVALGCMRMNALSEKEAQTMIETAVEHGINFFDHADIYGKGESEKIFANALKNSSIKREDIILQSKCGIGDKMYDFSKSHILQAVDGILERLQTDYLDILLLHRPDPLMEPEEVAEAFSELQDAGKVRQFGVSNFHPYQVELVQKFASQKLIVNQLQFSIAHTGMIDFGMHVNMKDERSINHDGGILEYSRLHDITIQAWSPFQYGFFEGVFIDDPKFPELNEKLGQLAQAQGVSKEAVATAWILRHPAKIQVIAGTMNPERLKKVTEASKVSLTRRDWYDIYFAAGNDLP
>CP026649.1|AVD57796.1|584963_585902_+|transposase
MELVMEKQAGYNVHDRLFKELIQNFFKEFMEAFFPDVSADLDYRRVRFLSQEQFTDFPGGEQKRVDILAETKVKGKDTVILIHVEPQSYYQKLFPERLFRYYMMISLRHRKPVLPIAVFSYEEKTETPDTYTFAFHNIEILRFHYLSIHLIKKNWRDYIRSNNPVAAALLSKMGYTKKERVQVKLEFLRMLARMELDPAKMRMLYGFFDFYLKLNEKEEAEVMENIKMLDPDEAEQVLKLPNSYFDRGYRKGKEEGREEGREEGREEGEEKLKRFIANLLKNQVDLKIIAQASGLSEEEILKIKRQIEGGKH
>CP026649.1|AVD55148.1|585898_586126_+|hypothetical-protein
MSPVCDEAEQVLKLPNSYFDRGYRKGKKEGREELLQTIPTAIKMLQEGMDLQFIVEKTGLSRPEVEKIKQQLEHS
>CP026649.1|AVD57797.1|586500_586824_+|DUF3870-domain-containing-protein
MQTAFIAGHAKLPSGMAAQNIYDTLTITAEIEMKYGVILDVSCTLATEHGRQFISHLLRGYSLNDGIEEPLKQLQEFYLGKASNALISAFKDLYRQYHLILKTKQGE
>CP026649.1|AVD55149.1|587066_588278_-|butyryl-CoA-dehydrogenase
MHFELTEEQELLKKTVRNFVDKEIMPNIREWDENHHFETSLLKKLADLGLMGVCIPEKYGGSGMDYNALAIVCEELERGDTAFRTAVSVHTGLNSLTLLQWGTEAQKQKYLVPQAKGEKIGAFGLTEPDAGSDVAGIGTTAEKDGDFYILNGQKTWISLCDVADHFLVFAYTDKAKKHHGISAFIVERTLPGFSSKAIKGKLGIRAGNTGELFFDNVRVPKENLLGEEGEGFKIAMSALDNGRFTVAAGACGLIQACLEASVKYCHERKTFGREIGKHQLVQQMIAKMEAGYQMSRLLVFRAGELKNQGKRNTRETSLAKWQACDFANEAANDAVQIHGAYGYSSEYPVERYLRNSKAPVIYEGTREIHTVMQAEYVLGYRTDKPLNKMLPAWPFDERDAEES

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Crispr_ID: CP026649_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026649_5

624195-624286

Orphan

Consensus_repeat	Method
TTCCTTTTCTGGTGTGGGCCGTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026649_5

>merge|CP026649|5|624195-624286|CRISPRCasFinder
TTCCTTTTCTGGTGTGGGCCGTTTTTTGTCGTTTTTGAGTCATATAGCGGCCGACTTTGCCCCGCAGCCTTCCTTTTCTGGTGTGGGCCGTA

>CP026649|5|3|624195-624286|CRISPRCasFinder
TTCCTTTTCTGGTGTGGGCCGTT	TTTTGTCGTTTTTGAGTCATATAGCGGCCGACTTTGCCCCGCAGCC
TTCCTTTTCTGGTGTGGGCCGTA

Protein	Signature genes	Signature genes Name	Protein_function
CP026649.1\|AVD55185.1\|632300_633893_-\|L-aspartate-oxidase	unknown	unknown	gnl\|CDD\|236147
CP026649.1\|AVD55180.1\|624436_625915_-\|carboxylesterase	unknown	unknown	gnl\|CDD\|225181
CP026649.1\|AVD55171.1\|616489_617635_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|130254
CP026649.1\|AVD55181.1\|626065_627643_+\|magnesium-chelatase	unknown	unknown	gnl\|CDD\|223679
CP026649.1\|AVD55174.1\|619226_620057_-\|short-chain-dehydrogenase/reductase-SDR	unknown	unknown	gnl\|CDD\|235935
CP026649.1\|AVD55178.1\|621935_622751_+\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|379207
CP026649.1\|AVD55182.1\|629057_630140_-\|alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|341451
CP026649.1\|AVD55186.1\|633976_635122_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|179511
CP026649.1\|AVD55172.1\|617832_618378_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224427
CP026649.1\|AVD55177.1\|621059_621632_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380348
CP026649.1\|AVD55170.1\|615824_616478_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224095
CP026649.1\|AVD57801.1\|635779_636307_+\|NYN-domain-containing-protein	unknown	unknown	gnl\|CDD\|350235
CP026649.1\|AVD55184.1\|631480_632332_-\|nicotinate-nucleotide-diphosphorylase-(carboxylating)	unknown	unknown	gnl\|CDD\|181221
CP026649.1\|AVD57800.1\|627587_628562_+\|transposase	unknown	unknown	gnl\|CDD\|227751
CP026649.1\|AVD55187.1\|636986_637775_+\|formate/nitrite-transporter	unknown	unknown	gnl\|CDD\|376497
CP026649.1\|AVD55179.1\|623374_624091_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293807
CP026649.1\|AVD55175.1\|620023_620629_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235935
CP026649.1\|AVD55173.1\|618392_618953_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100047
CP026649.1\|AVD55183.1\|630386_631484_-\|quinolinate-synthase-NadA	unknown	unknown	gnl\|CDD\|236489
CP026649.1\|AVD55176.1\|620615_620909_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP026649.1\|AVD55185.1\|632300_633893_-\|L-aspartate-oxidase	gnl\|CDD\|236147	PRK08071, PRK08071, L-aspartate oxidase; Provisional.	0
CP026649.1\|AVD55180.1\|624436_625915_-\|carboxylesterase	gnl\|CDD\|225181	COG2272, PnbA, Carboxylesterase type B [Lipid metabolism].	1.47965e-163
CP026649.1\|AVD55171.1\|616489_617635_-\|CBS-domain-containing-protein	gnl\|CDD\|130254	TIGR01186, Choline_transport_ATP-binding_protein_OpuBA, glycine betaine/L-proline transport ATP binding subunit. This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines].	2.3489e-173
CP026649.1\|AVD55184.1\|631480_632332_-\|nicotinate-nucleotide-diphosphorylase-(carboxylating)	gnl\|CDD\|181221	PRK08072, PRK08072, carboxylating nicotinate-nucleotide diphosphorylase.	2.42543e-158
CP026649.1\|AVD55174.1\|619226_620057_-\|short-chain-dehydrogenase/reductase-SDR	gnl\|CDD\|235935	PRK07109, PRK07109, short chain dehydrogenase; Provisional.	9.56495e-114
CP026649.1\|AVD55178.1\|621935_622751_+\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|379207	pfam13472, Lipase_GDSL_2, GDSL-like Lipase/Acylhydrolase family. This family of presumed lipases and related enzymes are similar to pfam00657.	4.28273e-19
CP026649.1\|AVD55182.1\|629057_630140_-\|alcohol-dehydrogenase	gnl\|CDD\|341451	cd08172, GlyDH-like, Glycerol_dehydrogenase-like. This family contains glycerol dehydrogenase (GlyDH)-like proteins that have yet to be characterized, but show sequence homology with glycerol dehydrogenase. Glycerol dehydrogenases (GlyDH) is a key enzyme in the glycerol dissimilation pathway. In anaerobic conditions, many microorganisms utilize glycerol as a source of carbon through coupled oxidative and reductive pathways. One of the pathways involves the oxidation of glycerol to dihydroxyacetone with the reduction of NAD+ to NADH catalyzed by glycerol dehydrogenases. Dihydroxyacetone is then phosphorylated by dihydroxyacetone kinase and enters the glycolytic pathway for further degradation. The activity of GlyDH is zinc-dependent; the zinc ion plays a role in stabilizing an alkoxide intermediate at the active site.	0
CP026649.1\|AVD55186.1\|633976_635122_+\|cysteine-desulfurase	gnl\|CDD\|179511	PRK02948, PRK02948, IscS subfamily cysteine desulfurase.	6.13531e-143
CP026649.1\|AVD55172.1\|617832_618378_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|224427	COG1510, COG1510, Predicted transcriptional regulators [Transcription].	6.36582e-49
CP026649.1\|AVD55177.1\|621059_621632_-\|cupin-domain-containing-protein	gnl\|CDD\|380348	cd02219, cupin_YjlB-like, Bacillus subtilis YjlB and related proteins, cupin domain. This family includes bacterial and fungal proteins homologous to YjlB, a Bacillus subtilis protein of unknown function with a cupin beta barrel fold. The active site of members of the cupin superfamily is generally located at the center of a conserved barrel and usually includes a metal ion. The different functional classes in this superfamily include single domain bacterial isomerases and epimerases involved in the modification of cell wall carbohydrates, two-domain bicupins such as the desiccation-tolerant seed storage globulins, and multidomain nuclear transcription factors involved in legume root nodulation.	2.08757e-74
CP026649.1\|AVD55170.1\|615824_616478_-\|ABC-transporter-permease	gnl\|CDD\|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	4.70388e-83
CP026649.1\|AVD57801.1\|635779_636307_+\|NYN-domain-containing-protein	gnl\|CDD\|350235	cd10911, PIN_LabA, PIN domain of Synechococcus elongatus LabA (low-amplitude and bright) and related proteins. This subfamily contains Synechococcus elongatus PCC 7942 LabA which participates in cyanobacterial circadian timing, it is required for negative feedback regulation of the autokinase/autophosphatase KaiC, a central component of the circadian clock system, and appears to be necessary for KaiC-dependent repression of gene expression. This subfamily belongs to the LabA-like domain family which includes the N-terminal domain of limkain b1, a human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes. Also included in the LabA-like domain family are human ZNF451, uncharacterized Bacillus subtilis YqxD, uncharacterized Escherichia coli YaiI, and the N-terminal domain of a well-conserved group of mainly bacterial proteins with no defined function, which contain a C-terminal LabA_like_C domain. Curiously Pseudomonas putida S16 NicB , which is described as a putative NADH-dependent hydroxylase involved in the microbial degradation of nicotine also falls into the LabA-like family. The PIN (PilT N terminus) domain belongs to a large nuclease superfamily. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	7.10375e-28
CP026649.1\|AVD57800.1\|627587_628562_+\|transposase	gnl\|CDD\|227751	COG5464, COG5464, Uncharacterized conserved protein [Function unknown].	5.53097e-09
CP026649.1\|AVD55187.1\|636986_637775_+\|formate/nitrite-transporter	gnl\|CDD\|376497	pfam01226, Form_Nir_trans, Formate/nitrite transporter.	2.01791e-82
CP026649.1\|AVD55179.1\|623374_624091_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293807	cd07721, yflN-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis yflN; MBL-fold metallo hydrolase domain. This subgroup includes the uncharacterized Bacillus subtilis yflN protein. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	8.06463e-76
CP026649.1\|AVD55175.1\|620023_620629_-\|hypothetical-protein	gnl\|CDD\|235935	PRK07109, PRK07109, short chain dehydrogenase; Provisional.	2.03338e-21
CP026649.1\|AVD55173.1\|618392_618953_+\|acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	2.16615e-104
CP026649.1\|AVD55183.1\|630386_631484_-\|quinolinate-synthase-NadA	gnl\|CDD\|236489	PRK09375, PRK09375, quinolinate synthase NadA.	2.7516e-154
CP026649.1\|AVD55181.1\|626065_627643_+\|magnesium-chelatase	gnl\|CDD\|223679	COG0606, COG0606, Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones].	8.17556e-166

>CP026649.1|AVD55179.1|623374_624091_+|MBL-fold-metallo-hydrolase
MKKIAEGVAMLEINLNHFIIHPTLIWDEQKAVLVDAGMPGSLDLIRAEMEKAGVPFEKLYAVILTHQDMDHIGSVPEILAESGHSITVYAHGLDKPYIEGERLLIKADPEKIDPARWESMPEEMKQMYLNPPKAKVDKVIGDGEVLPFGGGIEVIFTPGHTPGHCCLYLKKSKTLIAADAMVADNGKLHGPRQQVTPDMGTAMASLKKLLDFDIESVICYHGGLCHENVNEQIRKLAE
>CP026649.1|AVD55178.1|621935_622751_+|SGNH/GDSL-hydrolase-family-protein
MGKKGWLVVLLFFITAGVLGTGNWYYQANTGKTIEKAQQQYKKDLAKEKKRSLEAKAAKESAAKQIYEKHKGKELVYLPVGSSLTAGDFATKKSKTYAALLAARIHQGLGYKVKTINGYGKSGAGLKEHGADSLPHIIFNHPDLVTIEFGTFDLNRNAKNTYVSAGQFKKDLEHFVDEIRKSTGKKTKIILLTTWNSGQLSFTYDRAIEEVGKAKGVPVANIESVWLNRSDTHGQKGEKAATGKSDGWLANDKGHKEIANTVYKKAYGLLK
>CP026649.1|AVD55177.1|621059_621632_-|cupin-domain-containing-protein
MKRLLPFMSASDGKDAGGTAANDNVSAFYFEENGGIPNNPFLPVLIYHGVFKGRTDEIEKVFQKNNWGNNWVWTIFPYHHFHSNSHEVIAVRSGHAKVQLGGPQGKIFTISEGDCVLMPAGTGHKRIESGGGFAVTGGYPGGQDYDTQMRADETLRENIRKTGMPETDPVFGKNGPLFSYWTPEPGGKAG
>CP026649.1|AVD55176.1|620615_620909_-|hypothetical-protein
MKEILEQVKEKLENAYNHPNSADLDACIRQLQDARQQYGDKGTMIEDAITAIEQAKHSIPEHRHAGTDSAAGAFGQAYNALEHAIESFSGTENNDPF
>CP026649.1|AVD55175.1|620023_620629_-|hypothetical-protein
MIHFKRQIFKNNIVLHSNLGFSKVFLLFHPCSANRATILAKEANTLQMISAIAVSAISPMHPLKKKPNRAFPAFSIPEPPISKSCCCKNNRNQGIDILRNTAKKLQGGHTLDQSYVQQGNGSMDASMEKPLSLKKLADQVIVITGASSGIGLATARMAAARGARLVLAARNEHALKILANELKNNGSSAIWCGRMSATKKM
>CP026649.1|AVD55174.1|619226_620057_-|short-chain-dehydrogenase/reductase-SDR
MRADVGHEEDVKHIAATAIKTFGGFDTWVNNAGVSIFGEAMDVSIEDMKRMYDTNFWGAVYGTRLAVQHYKSRGVPGAVINIGSLFGDRGTVIQSTYASSKFALHGFTESIRMELEKEHAPVSITLVHPGRIDTPYNEQACSYLKKQPAHYMSMIYPPQAVAEAILFAAEHPKRDMYVGSQAKMVAVLGRFLPRFMDKLMELTMYRTQHSDRPSKSKADSALYHPGYGLHERGTNKGWMRRNSYYVKMSKYPLASAAIAAFVGAALWAAVSPRQKD
>CP026649.1|AVD55173.1|618392_618953_+|acetyltransferase
MSTEKEKMIAGKLYNAGDPELAQARLNARRLVRTFNETDETDLETRTALLKKLFGSTGERLFIESDFRCDYGFNIHVGENFYANFDCVILDGGPVEIGKNCMLAPGVHIYTATHPLDAKTRVSGLELTKPVKIGDNVWIGGRAVINPGVTIGNNAVIASGAVVVKDVPDNAVVGGNPARIIKMAES
>CP026649.1|AVD55172.1|617832_618378_+|MarR-family-transcriptional-regulator
MEEKTLDKVVQAKEQYIEKIADHIRAFGIPPTVGRVLGIIYMNHRPMTLDELSQATGMSKTRMSQVVREMVDMNIAEKVFEKGVRKDLYNVGLDFYDTFVAIFTSNLQKIIHRNKFFEKKFARELAELKANEELPPEMEKQLNNFLNELGNLAEYYDWLSRLVDFFESGKIFEYVPKKKQG
>CP026649.1|AVD55171.1|616489_617635_-|CBS-domain-containing-protein
MLKFDHVSKIYKGGKRAVDDLNLEFESGRFIVFIGPSGCGKTTTMKMINRLIEPTEGTIYINGKNIKNTDPVKLRREIGYVIQQIGLFPHMTIQQNISLVPRLLKWPEEKQRERAKELLQLVDMPEEFLDRYPHELSGGQQQRIGVLRALAADQPLILMDEPFGALDPITRDSLQDELKKLQKELGKTIVFVTHDMDEAIKLADQIVIMRDGKLVQTGTPDEILREPANEFVETFIGKERLLQARPNIQTVEQIMSPKAVTVTVDKTLTEAIQIMKERRVDSLLVVDSRKVLLGYIDVEIIDRNRRKPVLVKDMVETNLIAVEKDTLVRDTVRKILKRGIKYVPVVDHEHRLVGIVTRASLVDIVYDSIWGEEEAVSEIIS
>CP026649.1|AVD55170.1|615824_616478_-|ABC-transporter-permease
MEAFMQFMEANWSELLFKTWQHFYISITAVILGIVVAVPLGIWLTKYRRAAHIVMGIAGVIQTFPSLAILAFFIPIFGIGKLPAIAALFFYSVLPILRNTYTSVKGIDPKLVEAGRGMGMTGWERVIHLELPLAIPVIMAGVRLSTVYLIGWATLASFIGAGGLGDYIFSGLNLYQPEMIAAGAVPVTILALIVDYLFGKLETIATPKGIRKQKQAA
>CP026649.1|AVD55180.1|624436_625915_-|carboxylesterase
MKTAIVETVFGKARGYEEKGVQIWKGIPYAKPPIGPLRFRPPELPEPWAGVKDCTQFGPIAWQPPVELMDFLGNPAENMDEDCLNLNIWTPGADGERRPVMVWIHGGAFANGAGSAPSYDGSAFAKNGDVVVVTINYRLGALGFLYLGEMGGEKYEASGNCGILDQIAALKWVKENIAAFGGDPDCVTIFGESAGAMSVAALLSSPAASGLFHKAILESGAANFTATPERAAKNTRRILEALGLEKKDVAKLAEVPAKNLAEAVNSLPFMSLLPVTDGIVLPEHPERALENAAKDIPVLIGTNKDEYRLFTVFDPVWKRQDPKEMQDVFQKTFAKYWDALSAKITDPSAFTQELYDRIMTYFVFTGPALKLADTRAQTGEKVWMYQFDWESPVYNGTLKACHALEIPFVWHTLEQPGTENLTGNAPGRHALADRMHQAWIAFAQNGDPNCSLLPEWPPYNTRQRPAMIFGQDCRVEKDPHQAERALWGGLGE
>CP026649.1|AVD55181.1|626065_627643_+|magnesium-chelatase
MATIISSIGLKGIEGYCVHAEVQMMLGCGSGITIVGLPDASVKESKERIRGACSSIGCMLFQSKTIVNLSPADERKNSPALDLPIAIGLMAENHFFHARIPDHTAFLGALSLDGSVQAVAGMLPYVMAARGLGMKRLYLPASAELPFSQMDGMDIIFVQHLKDVLDSLSGKKLPPVRKKRQLQPDEYSFEADFSMILGHRHVKKVLEIAAAGSHNVLMYGPPGSGKSMLAEAFPSILPPLSETSSFEVAGLYQLANVKRGFHRKPPFRAPHHASSAVSLVGGGSRPHPGEISLAHHGVLFLDEMAEFPKRTLDMLRQPLENGKVTISRAASTVTYPARFIMLAAMNLCPCGYLGSPHAYCTCTPKQIQAYQNRISGPLLDRFDIFLPVGTVPLLEESGKINETSEQIRTRVTEARKRQYERYGAEVCNGTVPNEIFLQKNPLANSSSLMLRQWASKENFSSRAQMKILRLARTISDLQGSRELSEDALWQALQMKRNHLFGKRKVDAYATYNGRKSGVFAARPLV
>CP026649.1|AVD57800.1|627587_628562_+|transposase
MQLIMEEKAEYLPHDRLFKELIQTFFADFMEAFFPEVARWMDFSDVEFLQQDLFTDITAGEQRRIDILAKLKLKGEDTVVLIHVEPQSYYQMEFPERMFIYYSRIYEKYRLPVLPIAVFSYNKRRETPSLFTVRIRNFESIRFRYMSIHLIRKNWKEYIRSNNPVAAALLSKMGYTKKEKVQVKVEFLRMMARMELDPARMALIYGFFDSYFKLTDKEDELVMSSIKNLDPQEADQILRLPNSFYDKGYKKGKEEGKEEGKEEGKEEGLKEGLKEGERRAALRIAKRMLEENQDLASIAKYTGLAEEELKKLKQSGATRLRCDQ
>CP026649.1|AVD55182.1|629057_630140_-|alcohol-dehydrogenase
MRLSQVIRSGPNQYICEEDAAKYLEEKLKEFKYPVVITGVKSFKAFQKFASIPQNWPVLRYDHTASEKNMAKLAEQAGRADVIVGIGGGKVLDTAKGTAELLNCEVVLVPTLAGTCAGYTPLSAVYHEDGSFSHVAYYKRSAYLTLIDLRILLNAPAEYLLGGIGDSLAKWYEAEGITRSMKHLPVMVELGLRSAKAIYEGILRDSEQALHDRNEGKITDAFRNIVEIIIGAAGTVGGFAGEYGRMAGAHAIHNGLTFLPETHSILHGSKVAYGILVQLAATGDINEVKKLLPLYQKLGFPYNLDTLHVTENHGAAIEKVAAYAAKPEESFRLLGSFTKAQIAKAMETIEQLTAEKADIK
>CP026649.1|AVD55183.1|630386_631484_-|quinolinate-synthase-NadA
MSLLKTLQLTALPEKYQSLAQEEMENRVWDIKKEMGAKLFLPCHHYQREEVYQFADAAGDSLQLAQISAKNRNAKYIVFCGVHFMAETADILTSAEQTVILPDMRAGCSMADMADIHQTERAWDMLQSLFGDTMLPLTYVNSTAAIKAFVGRNGGATVTSSNAKKMVKWAFTQKERVFFLPDQHLGRNTAFDLGVELADMAVWDPIRNELIYEGALENVKVILWKGHCSVHEHFTIKNIEFVRAKYPDMQIIVHPECAHEVVALSDFSGSTKYIIDTIENAPAGSAWAIGTEMNLVQRLIKNHPDKKIISLNPVMCPCLTMNRINLPHLLWSLENIIEGKETNVIKVEENTARDAVLALERMLKL
>CP026649.1|AVD55184.1|631480_632332_-|nicotinate-nucleotide-diphosphorylase-(carboxylating)
MNKLQLQSMLKHFFMEDIGEGDINTEYIFSPDQPGKLTFIAKQNGIFCGKDVIEEGFRILDGTVRPRIFPRDGARIEKGAAIAEIRGPIVSLLSGERVILNLIQRMSGIATTTNAAVRETEGTHAKICDTRKTTPGLRMLEKYAVKAGGGFNHRRGLYDCVMLKDNHIAFAGSITKAVETVKASIGHTVKIEVEIETKDHLLEAVRAGADIIMFDNRTPEEICEWLPLVPPHIATEASGGITMENIRSYAETGVDWISLGFLTHSYQILDISAIVENTKEVAL
>CP026649.1|AVD55185.1|632300_633893_-|L-aspartate-oxidase
MKEKICILGSGIAALQLAVHLDSRYDVTIITKSQTKTSNSYKAQGGIAAVLSPEDRFEFHVKDTIRAGCRHHNEKEVEKLVKEGAAVVEELVKSGLPADRRPDGGLDLGLEGAHTVHRILHCGGDATGKFVIQHLLGQLGKSVRIIEHELAFELMVSAETGRVTGVKTKTADGNIRHYFSDHTVIATGGLGSLYPFTSNHPEIIGDGIAMAYRAGAELADMEFVQFHPTLLYAEGRAKGLVSEAVRGEGAVLVDENGSPVMAGVHPLKDLAPRHVVAHQIHQTIHSGKKVFLDIRKIKNFEKRFPTISRICRESGIDIHSGLLPIVPGSHFFMGGIVVDTYGRTTVNGLYAIGEAAASGVHGANRLASNSLLEGLVFGKRLAAFLNALEPEAAGGETAEIARPPLNPEIARRLDTVTLKKKMMENAGVIRSETGLRHLLQWLQARGADTFSAFSLGHLAKEEMEKVFMFTNSLLITQSALCRKESRGAHIRADYPDESSGWQGVHLIHAKNKGLITRRGLYEQAPTSIHA
>CP026649.1|AVD55186.1|633976_635122_+|cysteine-desulfurase
MFYFDYAATTKMSERARETFMEAAESFYGNSESLHDIGTDARAVLEKSRGLISGYLGVPAEGLYFTSGGTEGNLLAIVSLAMGASGRGKHIISSMAEHASVHSALGFLERLGFEVTRLPFTEKGTVDLKKLEAAIRPDTVLVSVQHINQEIGTIQPIEEISLMVRRRGILFHSDCVQSFGKADVARMIPYVDSITLSSHKIHGPKGVGAVYIHPSCVIAPVFPYLSHEKGFRGGTVNVPGIAGFAAAAEEILIESERDWEYRTALKEASGGTVVFIEGERAMQLPSIVGGMIPGVQGQLVLLECNKAGFAISTGSACQEHHEGGSKAVEAMGYAEEAMDQFFRISFGRHTTKKEILSLGETLKKIAAAHSAGTAMQDLFAR
>CP026649.1|AVD57801.1|635779_636307_+|NYN-domain-containing-protein
MVFIDGNNFEAALTALYGSQQRVDYLKLAEYVAARRDGMLQRIYYYTAVGNLDKAKAAATKSFIDHLNKKIPKCIAKLGYLSVVGTDASGNPIFTEKGTDVNIAVDLVSLAFHNGYDEAILFSADTDYEAAIKMARSLGKNVVAGVVDQQKAGYMKDLCDEYITLKKEDFNQCMR
>CP026649.1|AVD55187.1|636986_637775_+|formate/nitrite-transporter
MDLSPKEIADVAIEKGIAKANSSFLSMVVLGFLGGAFIAIGYLAYIRVTGTMPESWGSFDTFMGAAVFPTGLILILVGGGELVTGNMMAVSMACFDKKINILQLIWNWLWITIFNLIGALFVAYFFGHFIGLTEGDFLEKTVHTAEMKTSAPFWQAFVSGIGCNWLVSMAVWLCYGAKTFAGKILGIWFPIMAFVLIGFQHVVANMFIIPAAIFAGHLSWMLFLKNIIAVFLGNAAGAVVFVSMLYFIAYKKEGVQKTDTAL

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Crispr_ID: CP026649_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026649_6

975900-976178

Orphan

Consensus_repeat	Method
GATGAAAGACANNNNAAAG	CRT

5 spacers

The CRISPR arrays of CP026649_6

>merge|CP026649|6|975900-976178|CRT
GATGAAAGACATTTTAAAGGGTGGCGGGCGCCTATTTGTCCTTCACCGGTTTGATGAAAGACAAAACAAAGCGCGACTGCTTGCCATTTGTCCCTCATCGATGCGATGAAAGACAAAACAAGGTATGACGGGTATCGATTTGTCCTTCATCACCCCGATGAAAGACATTTTATAAGATGGCTGCCAGTATTCTGTCCTTCACCGGCATAATGAAAGACAAAACAAAGCGCAGCTGCCAGCCATTTGTCCTTCATCTGCCCGGTGAAAGACAAATCAAAG

>CP026649|6|3|975900-976178|CRT
GATGAAAGACATTTTAAAG	GGTGGCGGGCGCCTATTTGTCCTTCACCGGTTT
GATGAAAGACAAAACAAAG	CGCGACTGCTTGCCATTTGTCCCTCATCGATGC
GATGAAAGACAAAACAAGG	TATGACGGGTATCGATTTGTCCTTCATCACCCC
GATGAAAGACATTTTATAA	GATGGCTGCCAGTATTCTGTCCTTCACCGGCAT
AATGAAAGACAAAACAAAG	CGCAGCTGCCAGCCATTTGTCCTTCATCTGCCC
GGTGAAAGACAAATCAAAG

Protein	Signature genes	Signature genes Name	Protein_function
CP026649.1\|AVD55461.1\|984605_984812_-\|small-acid-soluble-spore-protein	unknown	unknown	gnl\|CDD\|365990
CP026649.1\|AVD55450.1\|972956_974468_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
CP026649.1\|AVD55448.1\|971691_972345_+\|pyrophosphatase-PpaX	unknown	unknown	gnl\|CDD\|237336
CP026649.1\|AVD55451.1\|974650_975598_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
CP026649.1\|AVD55458.1\|981492_982419_+\|transposase	unknown	unknown	gnl\|CDD\|273806
CP026649.1\|AVD55443.1\|963848_967445_-\|CDP-glycerol--glycerophosphate-glycerophosphotransferase	unknown	unknown	gnl\|CDD\|367953
CP026649.1\|AVD55454.1\|977769_978750_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
CP026649.1\|AVD55456.1\|979894_980164_+\|HPr-family-phosphocarrier-protein	unknown	unknown	gnl\|CDD\|172320
CP026649.1\|AVD55446.1\|969763_970717_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
CP026649.1\|AVD55447.1\|970780_971596_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
CP026649.1\|AVD55460.1\|983161_984550_+\|class-II-fumarate-hydratase	unknown	unknown	gnl\|CDD\|234779
CP026649.1\|AVD55442.1\|962912_963719_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224596
CP026649.1\|AVD55459.1\|982415_982691_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273806
CP026649.1\|AVD55445.1\|969008_969359_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224861
CP026649.1\|AVD55455.1\|978830_979784_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
CP026649.1\|AVD55444.1\|967744_968890_+\|DUF4097-domain-containing-protein	unknown	unknown	gnl\|CDD\|226123
CP026649.1\|AVD55457.1\|980250_980835_-\|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
CP026649.1\|AVD55449.1\|972341_972857_+\|acyltransferase	unknown	unknown	gnl\|CDD\|100053
CP026649.1\|AVD55453.1\|976882_977773_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|235450
CP026649.1\|AVD55452.1\|976387_976846_+\|8-oxo-dGTP-diphosphatase	unknown	unknown	gnl\|CDD\|239519

Protein	Function_ID	Function_description	E-value
CP026649.1\|AVD55461.1\|984605_984812_-\|small-acid-soluble-spore-protein	gnl\|CDD\|365990	pfam00269, SASP, Small, acid-soluble spore proteins, alpha/beta type.	7.24679e-25
CP026649.1\|AVD55450.1\|972956_974468_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.14343e-12
CP026649.1\|AVD55448.1\|971691_972345_+\|pyrophosphatase-PpaX	gnl\|CDD\|237336	PRK13288, PRK13288, pyrophosphatase PpaX; Provisional.	1.00107e-127
CP026649.1\|AVD55451.1\|974650_975598_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	1.82804e-153
CP026649.1\|AVD55458.1\|981492_982419_+\|transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	1.10565e-12
CP026649.1\|AVD55443.1\|963848_967445_-\|CDP-glycerol--glycerophosphate-glycerophosphotransferase	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	2.29605e-92
CP026649.1\|AVD55454.1\|977769_978750_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	2.26937e-159
CP026649.1\|AVD55456.1\|979894_980164_+\|HPr-family-phosphocarrier-protein	gnl\|CDD\|172320	PRK13782, PRK13782, HPr family phosphocarrier protein.	9.16542e-41
CP026649.1\|AVD55446.1\|969763_970717_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	3.35102e-174
CP026649.1\|AVD55447.1\|970780_971596_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	6.82454e-137
CP026649.1\|AVD55460.1\|983161_984550_+\|class-II-fumarate-hydratase	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
CP026649.1\|AVD55442.1\|962912_963719_+\|ABC-transporter-permease	gnl\|CDD\|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	4.20986e-51
CP026649.1\|AVD55459.1\|982415_982691_+\|hypothetical-protein	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	0.000711784
CP026649.1\|AVD55445.1\|969008_969359_+\|hypothetical-protein	gnl\|CDD\|224861	COG1950, COG1950, Predicted membrane protein [Function unknown].	6.83396e-21
CP026649.1\|AVD55455.1\|978830_979784_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	8.58946e-147
CP026649.1\|AVD55444.1\|967744_968890_+\|DUF4097-domain-containing-protein	gnl\|CDD\|226123	COG3595, COG3595, Uncharacterized conserved protein [Function unknown].	1.5029e-25
CP026649.1\|AVD55457.1\|980250_980835_-\|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	8.2757e-150
CP026649.1\|AVD55449.1\|972341_972857_+\|acyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	5.96808e-31
CP026649.1\|AVD55453.1\|976882_977773_+\|RNase-adapter-RapZ	gnl\|CDD\|235450	PRK05416, PRK05416, RNase adapter RapZ.	5.66519e-176
CP026649.1\|AVD55452.1\|976387_976846_+\|8-oxo-dGTP-diphosphatase	gnl\|CDD\|239519	cd03427, MTH1, MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the incorporation of such oxygen radicals during replication. This is an important step in the repair mechanism in genomic and mitochondrial DNA. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for activity, and contain the Nudix motif, a highly conserved 23-residue block (GX5EX7REUXEEXGU, where U = I, L or V), that functions as a metal binding and catalytic site. MTH1 is predominantly localized in the cytoplasm and mitochondria. Structurally, this enzyme adopts a similar fold to MutT despite low sequence similarity outside the conserved nudix motif. The most distinctive structural difference between MutT and MTH1 is the presence of a beta-hairpin, which is absent in MutT. This results in a much deeper and narrower substrate binding pocket. Mechanistically, MTH1 contains dual specificity for nucleotides that contain 2-OH-adenine bases and those that contain 8-oxo-guanine bases.	8.94661e-41

>CP026649.1|AVD55451.1|974650_975598_+|thioredoxin-disulfide-reductase
MSEEQIYDVIIIGAGPAGMTAAVYASRSDLKTLMIERGVPGGQMVNTEEVENYPGYESILGPELSNKMFEHAKKFGAEYAYGDIKGIEIDGDYKIVKAGAKAYKALAVIIATGAQYKKLGVKGENELGGRGVSYCAVCDGAFFKGKDLVVVGGGDSAVEEGNYLTRFANKVTIVHRRDQLRAQKILQDRAFKNEKIDFIWNHTVKEIHEENGKVGAVTLVSTVDGSEKPFKTDGVFIYIGMVPLTKPFENLGITNEAGYILTNEEMETKIPGIFAAGDVREKTLRQIVTATGDGSIAAQNAQHYVEEVKEAMKAG
>CP026649.1|AVD55450.1|972956_974468_+|tetratricopeptide-repeat-protein
MSKDSKLRQEHDNVLSFVPTGEYYFNKGVQAYDRHDIKKALKYMQRAAQLDPYDPVIACQLAIIYTHCEAFRKAIDIFRHILAKLDPGMVECHYFIANNYADLGFFNEALYHARKYLELDPFGEYREEAEELIYVLDLEEEDETGAISYEQDELMARQEEARRYLEAGHFDTALSELHKLIKKYPDFWSAYNNMALACFYLGQTEKAVEVLMDLLEKNPGNLHALCNLAVFYYHKRDDEKLEQILRGLEKVRPVLLDHQYKLGATFAIVGRYEEAYLWLNRLKKVGFDGDASFYYWLSRAAYHTNRQQAAEAAWEQLVELNPEKKGCEPWNREMEKKMNEKNVQFILDRLNSTELPERFFGIFMIGLSSNRSDIVSHPDFKPLDDFTLTEKIYLAHVLESDIRESFDPDEVFVRGHNIACILHSHYGPMFPGYTNLMLAWFSIFLTGLKRGERFQNESGFAAAIDYLWHHQKGDKVSQQAIAREYRISVSTLRKYANRIKSLL
>CP026649.1|AVD55449.1|972341_972857_+|acyltransferase
MRNTKRYPVKGSNALWQIYKTVSFWKVFKNVLVIEIARFLPFLRFKNQMYRTFLHMQVGDRTAFAYKALVDILFPEMITVGKNCVIGYHTTILAHEYLIDEYRIGEVVIGDDVMIGANTTILPGVTIGDRAVVAAGSVVHKDVPAGAFACGNPLQIRQKSSEKKDPEQTKR
>CP026649.1|AVD55448.1|971691_972345_+|pyrophosphatase-PpaX
MKNRITTLLFDFDGTLIDTNELIIQSFLYTLNAYYPGRYSREDVLIFNGPPLIDTFLSIDPERAEEMTAKYRTYNIQQHDALVKEFPGVYDTIKMLKEHRFKLGIVSTKMKDTIKKGLKLAKLDPFFDVIVALDDVKKAKPDPEPVQKALRLLGSKPEEAMMIGDNYHDIEAGKNAGTFSAGVAWSAKGRAFLEQYNPDFMLETMTDLAEIVGVHVK
>CP026649.1|AVD55447.1|970780_971596_+|prolipoprotein-diacylglyceryl-transferase
MDSNITPLNPIAFHLGGFSVHWYGIIIGCGILLGLALAMREADRLSVDQNIIADLCIWAIPVSIICARIYYVLFEWKYYAQHTSEIIKIWNGGIAIHGALIGAVVTAILFTRAKGVSFWKIADIVAPSLILGQAIGRWGNFMNQEAHGRAVSRAFLENLHLPDWIINQMYINGTYYQPTFLYESLWDLAGFIFLLLLRRRAAMHRGEIFLTYLIWYSIGRFFIEGLRTDSLMLTAHIRMAQVVSFILIVCALILWFYRRKTGLSAKRYDEE
>CP026649.1|AVD55446.1|969763_970717_+|HPr-kinase/phosphorylase
MAKVRVADMIKHFNLELISGEEGIHRPITTSDISRPGLEMTGFFDYYPADRIQLLGMTEITFSKRLSPEERKSRMDNLCSDITPGIVISRNLEVPDELIEASEEKSIPVMRTPMKTTRFSSRLTNYLEYKLAPATAIHGVLVDVYGVGVLITGKSGVGKSETALELVKRGHRLVADDCVEIVQEEEGSLIGHAPELIEHLLEIRGLGIINVMTLFGAGAVRSHKKITLIANLELWDEHKQYDRLGLDEEKVKILDTEITKMTVPVRPGRNLAIIIEVAAMNYRLKNMGVNAARQFTAKLANVIEEHEQGTEEEKNEP
>CP026649.1|AVD55445.1|969008_969359_+|hypothetical-protein
MIMRWLLGILINAALFIALSGYFHGFYVENIGAAVMSSLVLSILNILVRPILILLTLPITILTLGIFLLVINAITLVLTDELMGASFEIDSFGMAFFVAIIMAIVNLILQETVFRK
>CP026649.1|AVD55444.1|967744_968890_+|DUF4097-domain-containing-protein
MENKRKRILDMVKDGKLSTDEALTLLEALDREEAGQIAAKEDPAENGEQATNGGSGEAGSTTGQKKFRDADRNFNETKEKLFDLVGGALKKIKDFDLQLGQSAEVSHVFQQSLPETDTIELDIANGHLTFKQWDQEDVRIECQAKVYRTNDREDARSFLLNNSTFSVEGGRLVFSTQSKWMKVDTAVYVPASRYRKITLSTFNGNVQVKDIQADQLKVKTLHGKVLVEHADLETAEVETGNGTVDFDGNTIGQVEVQTMNGDIRWNGACRRSDFEAFNGNITVKMAPGADSLHSKTVSGNIEMTIPENISVHGEGKSNFGNFAIDLQGMEKYEERKEMIQKVARFSRKGTTEPALYIFADAKTGSITINEQTPDEEESPEA
>CP026649.1|AVD55443.1|963848_967445_-|CDP-glycerol--glycerophosphate-glycerophosphotransferase
MNKKVLKRRLKFIGAPIIQYLIKDNHQRANQYAKFYDQLRIKPNTILYESRDGKSMTDSPYAIFKYMVDNPAYQHYNHIWSIQDFQSLQPVIDKYKKYPNVKFVQRNSREYLKELASCAYLINNSTFQSFYAPKKGQVYINTWHGTPLKSMGFDIPGNPAQSQNVLRNFLSADYLLSPNEHTTKMYLDSYKLEGLYDGKIIEEGYPRIDLTFHTNPNTVKKALKDAGLTVDFNKKNLLYAPTWKGKSVSKANNDVMQIISDMDRVEKEAGNEYNVFVKVHPFLYPQAAKYPELQSRLVPDYMDTNELLAATDLLITDYSSIFFDYLVTGKPILFYTWDYDVYSEERGQYLKNEDLPGPLLFSVEQLIEAIHNIETVSQKYASNYQNLRSRFTNHEDGKVTERIVQYIFDQASLPLHIVNAVPVKKERILIYPGGMRNNGITSSFLNLMNNIDFEKYDVSCFTGAPRSKEVLNNIYKINKNVRMIFKPGVPLYRVFEVYRDKFTHNRGIQGNLGKKIFPERAYVREHTRLFGNSHFDYIIDFSGYSYYWAKYLVVADAKRKICFMHNDLLSDSEREINGKHPHRINLRGLFTLYYRFDKLVSVSKGTMEVNRKNLSRYANDDQFDYVLNSINPDRILYAEEEKSDEPKITKFKARALLSNVNDYPVWRVLPSIEGATQVSLSNEMANAEVLITAKSTVKHALYYRFHYEGKEIGWIHEKAVALLPDSVVTSEKVDKLAKIVKTRGNAIWSKPFKLPGTRKISLSSDFKNCIVAVDQAVQTQHSTYYRFSVKKEAIGWIDKRALGFYSSCTIEPNTGIFSKLKIFVLRKLIQTLNYSKREFLNHLDGRTRRLVDLRKPKYYKVAGSVNEPIWNKPYPNHKAKMVEEALNYKDAIVTVKKLAKTKQGVYALIYLKNNKIGWIHTSALSPLKRSTVVSDIEVLKIARILPDEKNAVIWSKPYGMEGAEKAGLPDMLKGDATFTIDREVTTPSGTYGRILQADGPEIGWINMRNVFVERAYGYEVNGQYVPEPDSSHYNFVNMGRLSPEKAQANLISAFADFHKNHPKSKLYILGQGPLKAELQALILELGVSDSVFLMGQLDNPFPFMKKCDCFVLSSHYEGQPMVLLEALTLGMKIVATDIVANRTVLEDGKYGLLVEDSINGLKSGLEAMITHQHPEFEKFHYQAYNKAAMETFYRCLHE
>CP026649.1|AVD55442.1|962912_963719_+|ABC-transporter-permease
MKSAITVLKEQFNSFYLIIRLSLYEVRSENRNNYLGILWEVINPMIQLAIYWFVFGFGLRGGHPRPGYIPWLFAGSSIWFFISPAVLQGSRSIYSRIRMVAKMNFPLSAIPSYVIMSKFYQHLLLLAIVIIILQFQGYPVSVYYLELPYYLVCTFVFTFSLSLITSTLATIVRDVQNIVQAIMRMMIYILPVLWDPSARLHGPIELILKLNPYYYIVEGYRSALLGNMGWYLVEHLHYTIYFWAVTLIVFMIGSALHIKFRNSFVDFL
>CP026649.1|AVD55452.1|976387_976846_+|8-oxo-dGTP-diphosphatase
MQRITNCVFIKDGQVLLLQKPRRNWWVAPGGKMEQGETVREAVIREYREETGIYLKHPDLKGVFTIVIKDGDKPVSEWMMFTFVATDGDGKNFEQSAEGILQWHAIDEMKNLPMAAGDTHILEYMVHGSGIIYGQFTYTPDFELLSYRLDPS
>CP026649.1|AVD55453.1|976882_977773_+|RNase-adapter-RapZ
MGLEGNQMQFVIITGMSGAGKTVAIQSLEDLGFFCVDNLPPTLLPKFLELMKDASNKMNKVALVMDLRGREFFDDLFRALDELDKSSWVTPTILFLDADDSVLVRRYKETRRSHPLSPDGTPLEGIQQERKILEELKGRAQLILNTSNLKPRELREKIVLEFSANRQSVFTVNVLSFGFKNGIPIDCDLVFDVRFLPNPFYIEHMRPKTGLDEEVYTYVLKWNETQKFLEKLTDLLAFMLPHYKREGKSQLVIGIGCTGGQHRSVALAEYIGHFFEKDYHTTISHRDIKRKEERKP
>CP026649.1|AVD55454.1|977769_978750_+|YvcK-family-protein
MRHPKIVLIGGGTGLPVLLRGLKKYPVEISAIVTVADDGGSSGRIRNEMDIPSPGDIRNVLAALSDVEPLLEKMFQHRFETGDELSGHSLGNLIIAALTSITGDFVHAVKELSKVLNVRGQVLPSANQSVVLHAEMEDGSIVSGESKIPCAGKKIKRVFLTPEVIQPLPETLTAIQEADLIVIGPGSLYTSILPNLMVPGLGEAVCQAHAKKVYVCNLMTQAGETNHYTAADHVQAILNHMGSACIDTILVNDEDVPEPVMSRYREELAQPVVYDVKRLMGLGLEVVSGNILTYKGGVIRHDTEKVAEILYDILKKQQWLSRSSAR
>CP026649.1|AVD55455.1|978830_979784_+|DNA-binding-protein-WhiA
MSFASEIKKELTNLAVKDCCVRSELSALIRMNGSLSFSNKVLVVNVQTENAAIARRIYVLVKRLYDVPVELLVRKKMRLKKNNVYIVRLKARAKEILEDLHILGEHFTFTRNISPELLKKKCCKRSYLRGAFLAGGSVNNPETSSYHLEISSQYKEHNDALCRLMNGFHLNSKTLERKKGYITYLKEAEKITEFLNIIGAHHALLRFEDVRIVRDMRNSVNRLVNCETANLNKTIGAALRQVENIRYIEETVGLDALPEKLREIAVLRVNHQDVTLKELGEMVSGGHISKSGINHRLRKIDEIAEKLRANGPANKNS
>CP026649.1|AVD55456.1|979894_980164_+|HPr-family-phosphocarrier-protein
MIEKQLEVKLKSGLQARPAAQFVQEATRFSSEIFLEKEGRKVNAKSIMGLMTLAAGHGETVTLSVDGSDEEEAFEHLANYIEGKEKLPS
>CP026649.1|AVD55457.1|980250_980835_-|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVSNSIVSQLLFLEAENPEKDIYLYINSPGGSVTAGLAIYDTMQIIKPDVQTICVGMAASMGSVLLTAGTKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKHILYTRAKLNKILSDHTGQPIEVIERDTDRDNFMSAEKAKEYGLIDHIMTKKN
>CP026649.1|AVD55458.1|981492_982419_+|transposase
MELVMEKHAGYHVHDRLFKELIQNFFQVFMEAFFPDVSADLDYRRVRFLSQEQFTDFPGGEQKRVDILAETKVKGKDTVILIHVEPQSYYEKSFPERMFRYYMMINLRHRKPVLPIAVFSYEEKTETPDTYTFAFHNIEILRFHYLSIHLMKQNWRNYIRSDNPVAAALLSKMGYTEKERVQVKLEFLRMLARMELDPAKMRLLYGFFDYYLKLNEKEEAEVMENIKMLDPDEAEQVLKLPNSYFDRGYKKGKEEGREEGREEGEERLRRFIVNLLKNQVDVKVIAQASGLSEDEIMKIKRQIEGEKP
>CP026649.1|AVD55459.1|982415_982691_+|hypothetical-protein
MNPSYDEAEQVLKLPNSYFDRGYKKGIEIGVEKGREEGREEERKELLQTIPIAIKMLLAGTELQLIVEKTGLSQTEVEKIKQQLETKQDKY
>CP026649.1|AVD55460.1|983161_984550_+|class-II-fumarate-hydratase
MEYRIEKDTLGEMKVPRDKYWGAQTQRSKENFPIGGEKMPMEVIRAFAHLKKAAAVSNNRLGKLSDAKMKAIVQACEEVLDGKFDEHFPLVVWQTGSGTQSNMNVNEVVARRANEILSGENSAEHVHPNDDVNMSQSSNDTFPTAMHIAAYHELQTRLLPPLEQLKETLLEKEKAYMKIIKIGRTHLQDATPLTLGQEISGWRAMLEKSERMIKESAKHILNLAIGGTAVGTGINADPTFGDKVAEELEKQTGYPFVSSDNKFHALTSHDEIVHVHGALKGLAADLMKMANDVRWLASGPRSGIGEITIPANEPGSSIMPGKVNPTQCEALTMVAVQVFGNDAAIGFAASQGNFELNVFKPVIIYNFLQSVHLLGDAMKSFDERCVRGIEPNVETIQENVNRSLMLVTALNPHIGYEKAAQIAKLAFKEGTTLKEAAIKTGYVTEEQYEEWIVPEKMVNLNH
>CP026649.1|AVD55461.1|984605_984812_-|small-acid-soluble-spore-protein
MANNSNSNQLLVSGAEQALDQMKYEIAQEFGVNLGADTTSRANGSVGGEITKRLVQMAEQQLGGTFHS

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Crispr_ID: CP026649_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026649_7

1003692-1003784

Orphan

Consensus_repeat	Method
ACACGGTGGTGAAACGCACAAGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026649_7

>merge|CP026649|7|1003692-1003784|CRISPRCasFinder
ACACGGTGGTGAAACGCACAAGCAGTAAACCAGTTTGTCCTGGCCGTAGTCGTCTTTTTCCTAATTTCAACACGGCGGTGAAACGCACAAGCA

>CP026649|7|4|1003692-1003784|CRISPRCasFinder
ACACGGTGGTGAAACGCACAAGCA	GTAAACCAGTTTGTCCTGGCCGTAGTCGTCTTTTTCCTAATTTCA
ACACGGCGGTGAAACGCACAAGCA

Protein	Signature genes	Signature genes Name	Protein_function
CP026649.1\|AVD55479.1\|1004951_1005146_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|290852
CP026649.1\|AVD55471.1\|995478_996261_+\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|236073
CP026649.1\|AVD55470.1\|994469_995336_+\|HAD-family-phosphatase	unknown	unknown	gnl\|CDD\|319818
CP026649.1\|AVD55472.1\|996265_996451_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379480
CP026649.1\|AVD55482.1\|1007008_1007338_+\|DUF1878-domain-containing-protein	unknown	unknown	gnl\|CDD\|370213
CP026649.1\|AVD55477.1\|1000671_1003659_+\|nucleoside-triphosphate-hydrolase	unknown	unknown	gnl\|CDD\|227061
CP026649.1\|AVD55476.1\|999403_1000675_+\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|277319
CP026649.1\|AVD55485.1\|1008790_1008979_+\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD55469.1\|994004_994352_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237467
CP026649.1\|AVD55475.1\|998427_999282_+\|TIGR03943-family-protein	unknown	unknown	gnl\|CDD\|226214
CP026649.1\|AVD55474.1\|997485_998415_+\|permease	unknown	unknown	gnl\|CDD\|223773
CP026649.1\|AVD55473.1\|996511_997291_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|163429
CP026649.1\|AVD57815.1\|1009780_1010194_-\|HIT-family-protein	unknown	unknown	gnl\|CDD\|223611
CP026649.1\|AVD55483.1\|1007352_1007919_-\|HTH-type-transcriptional-regulator-Hpr	unknown	unknown	gnl\|CDD\|237501
CP026649.1\|AVD55478.1\|1003870_1004815_+\|3'-5'-exoribonuclease-YhaM	unknown	unknown	gnl\|CDD\|237394
CP026649.1\|AVD55468.1\|992677_993811_+\|DUF445-domain-containing-protein	unknown	unknown	gnl\|CDD\|226834
CP026649.1\|AVD55480.1\|1005194_1006067_-\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|101162
CP026649.1\|AVD55486.1\|1009023_1009548_-\|tryptophan-transporter	unknown	unknown	gnl\|CDD\|293704
CP026649.1\|AVD55481.1\|1006366_1006459_+\|YjcZ-family-sporulation-protein	unknown	unknown	unknown
CP026649.1\|AVD55484.1\|1008063_1008426_-\|YtxH-domain-containing-protein	unknown	unknown	gnl\|CDD\|227313

Protein	Function_ID	Function_description	E-value
CP026649.1\|AVD55479.1\|1004951_1005146_+\|hypothetical-protein	gnl\|CDD\|290852	pfam14147, Spore_YhaL, Sporulation protein YhaL. This family of proteins is involved in sporulation. In B. subtilis its expression is regulated by the early mother-cell-specific transcription factor sigma-E.	1.6484e-19
CP026649.1\|AVD55471.1\|995478_996261_+\|enoyl-CoA-hydratase	gnl\|CDD\|236073	PRK07659, PRK07659, enoyl-CoA hydratase; Provisional.	9.93735e-121
CP026649.1\|AVD55470.1\|994469_995336_+\|HAD-family-phosphatase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.54784e-63
CP026649.1\|AVD55472.1\|996265_996451_+\|hypothetical-protein	gnl\|CDD\|379480	pfam14120, YhzD, YhzD-like protein. The YhzD-like protein family includes the B. subtilis YhzD protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length. There is a conserved GKL sequence motif.	1.39029e-29
CP026649.1\|AVD55482.1\|1007008_1007338_+\|DUF1878-domain-containing-protein	gnl\|CDD\|370213	pfam08963, DUF1878, Protein of unknown function (DUF1878). This domain is found in a set of hypothetical bacterial proteins.	5.90444e-46
CP026649.1\|AVD55477.1\|1000671_1003659_+\|nucleoside-triphosphate-hydrolase	gnl\|CDD\|227061	COG4717, COG4717, Uncharacterized conserved protein [Function unknown].	2.80716e-117
CP026649.1\|AVD55476.1\|999403_1000675_+\|metallophosphoesterase	gnl\|CDD\|277319	cd00840, MPP_Mre11_N, Mre11 nuclease, N-terminal metallophosphatase domain. Mre11 (also known as SbcD in Escherichia coli) is a subunit of the MRX protein complex. This complex includes: Mre11, Rad50, and Xrs2/Nbs1, and plays a vital role in several nuclear processes including DNA double-strand break repair, telomere length maintenance, cell cycle checkpoint control, and meiotic recombination, in eukaryotes. During double-strand break repair, the MRX complex is required to hold the two ends of a broken chromosome together. In vitro studies show that Mre11 has 3'-5' exonuclease activity on dsDNA templates and endonuclease activity on dsDNA and ssDNA templates. In addition to the N-terminal phosphatase domain, the eukaryotic MRE11 members of this family have a C-terminal DNA binding domain (not included in this alignment model). MRE11-like proteins are found in prokaryotes and archaea was well as in eukaryotes. Mre11 belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	3.97125e-56
CP026649.1\|AVD55469.1\|994004_994352_+\|hypothetical-protein	gnl\|CDD\|237467	PRK13676, PRK13676, YlbF/YmcA family competence regulator.	3.73763e-31
CP026649.1\|AVD55475.1\|998427_999282_+\|TIGR03943-family-protein	gnl\|CDD\|226214	COG3689, COG3689, Predicted membrane protein [Function unknown].	1.80849e-83
CP026649.1\|AVD55474.1\|997485_998415_+\|permease	gnl\|CDD\|223773	COG0701, COG0701, Predicted permeases [General function prediction only].	2.43598e-70
CP026649.1\|AVD55473.1\|996511_997291_-\|hypothetical-protein	gnl\|CDD\|163429	TIGR03717, R_switched_YjbE, integral membrane protein, YjbE family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family commonly are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains protein YjbE from Bacillus subtilis. A transport function is proposed.	2.28041e-70
CP026649.1\|AVD57815.1\|1009780_1010194_-\|HIT-family-protein	gnl\|CDD\|223611	COG0537, Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only].	2.07848e-57
CP026649.1\|AVD55483.1\|1007352_1007919_-\|HTH-type-transcriptional-regulator-Hpr	gnl\|CDD\|237501	PRK13777, PRK13777, HTH-type transcriptional regulator Hpr.	8.52725e-105
CP026649.1\|AVD55478.1\|1003870_1004815_+\|3'-5'-exoribonuclease-YhaM	gnl\|CDD\|237394	PRK13480, PRK13480, 3'-5' exoribonuclease YhaM; Provisional.	0
CP026649.1\|AVD55468.1\|992677_993811_+\|DUF445-domain-containing-protein	gnl\|CDD\|226834	COG4399, COG4399, Uncharacterized protein conserved in bacteria [Function unknown].	7.07983e-91
CP026649.1\|AVD55480.1\|1005194_1006067_-\|peptidylprolyl-isomerase	gnl\|CDD\|101162	PRK03002, prsA, peptidylprolyl isomerase PrsA.	1.80708e-65
CP026649.1\|AVD55486.1\|1009023_1009548_-\|tryptophan-transporter	gnl\|CDD\|293704	pfam17099, TrpP, Tryptophan transporter TrpP. TrpP is a bacterial transmembrane protein that is probably involved in tryptophan uptake. Its expression is regulated by tryptophan-activated RNA-binding regulatory protein (TRAP).	1.80694e-38
CP026649.1\|AVD55484.1\|1008063_1008426_-\|YtxH-domain-containing-protein	gnl\|CDD\|227313	COG4980, GvpP, Gas vesicle protein [General function prediction only].	1.23288e-13

>CP026649.1|AVD55477.1|1000671_1003659_+|nucleoside-triphosphate-hydrolase
MKIREVHIYGSGRLVDFHMENLSDLQVIYGENEAGKSTFMAFIEAVLFGFPSRQQNGQHYEPKFSPVYGGRLVLETEKDGKITVERIKGRAAGEVSVTFADGRTGGEEVLAQVLNGLNRQMFQSIYSFNLQSLQEIRKLTGDDFSRYLFAAGTIGTDALLSAERELEKEMEARFKPNGRKPVLNVQLRKLQAMEKELNHLKAENGRYGEWKARLATIEAAQEEAEAELEALRGTVQQYEHLTSLWPLYAERKHIKLQLAEIGPVRFPADGIRRLDALMSEWRASTGRLSAVKKQKQVLVEKMEGEQPDPLFVRHEGEIKKLLDDWPQYRGWQAEAERLQSEREILDSQISELSGMLHLTASQVEKVPQLDLSIAAKERLSTLIKAYDHHRSRNDALQAQLEDLRARMNAVEQQCALLEKELVSEEAFRDLSAKRQEKEKKSLLEADIRRGKQQLSRLKKMADEARKPPVLFFGLALLFLMAGVWSLLTGQYLFLGVFVLGAIVSGYHALKGKRNPFEEEIRALEQELEEEEKELRNWKDGDTDWHEYERQKQLRENWKQLILKLEEGEQNGRQMQNRKQRLEAEERQLLAEISHFRQTLQLGDGFRPGQLPDAFQLLTDLSGKLRERSRIEKKLAQLSASQSAFAERMENLWSRLHVNWPLRQEGILLLQQACAEQQERKIRLQEWEKKCAELEEQLQLLESEAEATDKEIKKLFALAGAANEEDFRKAGSLFQQYEKLTGQLEIIDLRISREDLERLERIEDVSIFEQEKQKLEEKIAEKANALRSMRKEAAEIRFELDRLEKGGTFTEKLHEYYSALSDFREEAFEWARFATAKRLLSGMMKRLRETRFPQVLNKAEAYLQSLTNGSYVSLHMGGEDGRFYVKRRDDVLFAANELSQATAEQLYIALRFSLAEALGGEFPSPVVIDDGFVNFDIYRTEKMARLLDQVSESRQVLLFTCQQPMLRFFKGHEVKTLGAIHGQELTGSGNISRIQP
>CP026649.1|AVD55476.1|999403_1000675_+|metallophosphoesterase
MEKCRLFFYERGMALKRIRFVHAADLHLDSPFAGLRKLPPALFERVKESTFRAFKNLCDLTIEKEADFLLICGDLYDGEDRSLKAQVRLKKQFERLQEAGISVFVLHGNHDHLSGSWTKLDMPANVRIFSERVEAKSFTAKNGSKVHVYGFSYPKRHVLENKTDEYRKTGDADFHIGMLHGYLEGGTKMHHPYAPFALQDLLEKGMDYWALGHIHKQQILHTHPYIIYPGNIQGRNRKETGPKGCMVTEMDPLGTHTAFYETADILWEKRTVSVKGANDFNRLYTVCRNALEEERKEAQGVFLQLDIKDPDLLDDEALGKVKNGELMEVLQEGEEADRNFVWVHRITLPENVLISARDDGFILQEMKKTLAQLEETAVDEAVSPLYSHMVAGRYLDLDGDEKQRLLLEAEAAVFEKLKGRGKR
>CP026649.1|AVD55475.1|998427_999282_+|TIGR03943-family-protein
MLRFIVLFGFAYFFMKLHATGDISKYINMKYAYLSFSMIFAMGFLCLYQLVKWVRAGNEAHDHHHAAHHGHSHETDENTWYKKMFTYGMILIPVVTGIFLPVATLNSTVVKAKGFHFSMIDNDKDQYANHQILRPNSSLYYDKDQYTEMESSDLKKYSKLQSIVLDDDHYFHGLETIYNYPGNFIGKKVAIKGFVYRTDDIKANQLFVLRFGIIHCIADAGVYGMLVDFPDNMANVKENTWIEVEGKLDTTYYTPFKENIPYLKVTSYHKSSEPKDPYVYRQYN
>CP026649.1|AVD55474.1|997485_998415_+|permease
MSVIEKGVRYAVMGQSLLQMNTIFISIIIEALPFIVLGVFISAVIQMFVTEEMIAKVMPKNRFLSIAFGTGMGALFPACECGIVPITERLVRKNVPLSAAIAFMLTGPIINPVVIFSTFVAFGDSWKMALLRCGLAIFTAVLTAIAISYFFSENQLREFVEAKLHHHGHDHEAHDKPNFLQKITGTIDHAIDEFFSVGKFLVFGGLISAAMQTFFRTSTLLSLGQTKMAAILIMMLLAFIMSICSEADAFIASSFNGMFGTSAILAFLVFGAMVDIKNLLMMMHSFKRKFVFSMIGLIIVFVFTGAFLI
>CP026649.1|AVD55473.1|996511_997291_-|hypothetical-protein
MKQLPVSIFDFGLVVSAGAFVALLKIIMIDIILSGDNAVVIAMATRKLQREQQNKAIFWGTAGAVILRILLAMAIVALLKIPYVNVIGGLLLLWIAYKVLGGGDENVHVKAKNGLLVSIGTIIMADAIMSLDNVVALAGASNGHIGMIALGVAISIPVMIFGSKMIVKAMNRYSWIAYVGSGILAWTAAEMLFKDEQILKWLNISHGPVTYTIGGILTVLVLFLGWLSNRRAAVKQVKQVKRDIKKDVKQDVQQRVHIH
>CP026649.1|AVD55472.1|996265_996451_+|hypothetical-protein
MRDYKLTAFEPTGEKILDEGFEAQDDTEAKKKGEALLKEKGVDEKTHRCVSPEGKLILFHR
>CP026649.1|AVD55471.1|995478_996261_+|enoyl-CoA-hydratase
MISTYETIKVEEKDGAAYLYFNRPDAMNALNLEMIKELADTLKAIAMKDDIHILVLSGNGKAFSAGGDIKAMLAMEEEKGFTSFMNQINEAVSILVGMPKLTIAAINGAAAGLGLSLALACDTIISDLDSKIAMNFIGIGLVPDGGGHYLLQRRIGQEKAKKVIWEGKVMSAEEAAETGIIDEAVPDLALAVDQKITEWQKKPVLAMIKTKKIYTELNRPDFNKSLELEKHAQWKMRQTKDHKEGIRAFVEKRAPQFKGE
>CP026649.1|AVD55470.1|994469_995336_+|HAD-family-phosphatase
MIYKMLALNIEGTLLQDNGRLGKTTKEAIEYAGAKGIAVTLITSKNFASAHRIAKWLKLHSSLITHQGAYIASELDKPIFVRRISEEATRDLVRLLEGFHAQIRLVSERFTLSNRVKHPNKLMGKVIYQTSNPFSYAEQYVDDLSAKLEQTPLSPPKIEVIFSDGEDIQAAKKAITNMFHEVDCIFCGNGKLDIVPAGISKLRGLLYVCDRMNIRREEVVVIGSGLDDLPLVEWAGLGVAMGNAHPAVKNASDWVTRSNNENGVSYMVKEHFRKQQPIDFLKKMKLLK
>CP026649.1|AVD55469.1|994004_994352_+|hypothetical-protein
MPSHLNEYARMLEKGIRESHEFAALKQAYENVRSNGQARALFDRFRQLQLNLQDKQMQGLPVTEEDEKQAQAAMQAVQSNPAIMQLIGAEQRLSDLLSEINQVLMRPVEDLYAGK
>CP026649.1|AVD55468.1|992677_993811_+|DUF445-domain-containing-protein
MHAFLEILFMTVVGAVIGGFTNYLAIKMLFRPYEAIYIKNWRLPFTPGLIPKRREEIAKQLGEMVVRHLVTPESIEKKLLSPGFRKETARWMTDTFLKWLEMSWTAPQMARFFKVDLSAERVQTGIKAFIRTRYGQAKQHIAPQTLEALLPEAVIKKAEEKIPVLADLIIARISEYISSPAGRTKIEGMISHFLDDRGMIGAMVKRFIGNTSIADKIQPEIIRALQEPGMKATMAEMLEREWNGLKAKQAGELLPDLPDEEISGWLEKNVLSLLPVERFLDTPVQAFVARYRNKIEEEWIPVLAEKALHLISENVHLIIRKLQVADLVRQEVESFPIERLESLILGITAREFSMITYLGALLGGLIGIVQGVIVLLV
>CP026649.1|AVD55478.1|1003870_1004815_+|3'-5'-exoribonuclease-YhaM
MAKGLLYYEVGEQFDAFLLIKHATKGIASNGKPFLTLILQDRTGDIEAKLWDATEQDEQTYKPETIVKVTGDILNYRGRLQLKIRQIHPAQPGDGVRISDFIETAPLSQEEMMGKITQYIFDMKNPNIQRLTRHLLKKYQKRFLVYPAATKNHHEFVSGLAYHVVSMLDLAKAIAGLYPSLDRDLLYAGVILHDLGKVQELSGPISTTYTAEGNLLGHISIMVTEIAKAAEELGIHGEEVMVLEHMVISHHGKAEWGSAKPPMIKEAEILHYIDNIDAKMNMLDRALRNVKPGEFSDRIYALDNRSFYKPTFHQ
>CP026649.1|AVD55479.1|1004951_1005146_+|hypothetical-protein
MDFPIWIYFVVAGIVICAFMAVKTAREEHEQEQEWIEKEGEVFIERMHKEKELRSGEAEKAHEA
>CP026649.1|AVD55480.1|1005194_1006067_-|peptidylprolyl-isomerase
MKKWVLSLVLAGSMFGLAACGNSGNSAVVKTNAGNVTKDELYNAMKDKYGSTVLQQLTIEKVLSKKYTVKKSEIDKQVNDTKKQLGSSFNTALQQYGYASEKDFRNSVKVGLLEQKAAEATIHPTEKQLKNYYNNDIKPKIKARHILVSSKSKAEDIKKQLDKGADFATLAKKYSTDTATASKGGDLGWFGAGEMDSDFENAAYKLKVNEISGPVKTSYGYHIIQLTGEKQKKPYSEMKKDVVKQYKESKVTTEKIQSVLKKELKAADIKVKDEDLKTTFDTLLGTSSSK
>CP026649.1|AVD55481.1|1006366_1006459_+|YjcZ-family-sporulation-protein
MSGGAAYGGGFALLVVLFILLIIIGASWAW
>CP026649.1|AVD55482.1|1007008_1007338_+|DUF1878-domain-containing-protein
MESIEQKLERLEFYQTLLLKMIGTSQYPFFRLIMEKQLSKQDIEQFYALCDRLSDELKEQKADKFVYFYPLFQKFKESLHEKLQPAEVIAACLQQGLYPDLMKALKRNL
>CP026649.1|AVD55483.1|1007352_1007919_-|HTH-type-transcriptional-regulator-Hpr
MTEQILTTNEYLLFCKRVTQLSKALWKTIEKDWQQWIKPFDLNINEHHILWIAYHLKGASISDVAKFGVMHVSTAFNFSKKLEERGLLEFSKKENDKRNTYIQLTNKGREIFLKSLEAFNPKKSTVVQGTMPLYDLYGKFPDMMELAAIVRQIYGQDFMDIVENSIFNGELDDVIETELLGKPSLNRF
>CP026649.1|AVD55484.1|1008063_1008426_-|YtxH-domain-containing-protein
MNKSSLFYGLLVGATAGAVSVLFTTPASGKRIREAIKNNSGDFIESVKRIAENVKDLKASVEDFSTEGKKVATNVMEEIQHCIEEWQKSIEPNKDALQNEIKEIRKTIENMEQQMEKKSS
>CP026649.1|AVD55485.1|1008790_1008979_+|hypothetical-protein
MGRVAFCFLMAGVVLFAAMVRHMLLYQKRRIYPPRKIIRKRIAFFGTAGMVFLLLAALFHLF
>CP026649.1|AVD55486.1|1009023_1009548_-|tryptophan-transporter
MKTKSLVSLALLVGIGTVLHTVIPGFVFGMKPDMMLTMMFIGIILFREKKYVLLLGVLTGIISGLTTSFPGGFFPNIIDKCITSFAFYGLLLASGKLAKKLPALIVFTAIGTLISGIIFLGSAFFIAGLPGPFAILFGTVVLPATVLNAVAMFILFPIISTVAKRTNAAHSMQA
>CP026649.1|AVD57815.1|1009780_1010194_-|HIT-family-protein
MCIFCKIINGEIPSAKVYENEHVYAFLDISQVTKGHTLIVPKIHKENVYELTPEIARNFFESVPVVANALKAAFQPVGLNVLNNNGEIAGQSVFHYHMHLIPRYGKGDGFGAVWKTHEKDYSQEDLQQIAAEISKKI

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Crispr_ID: CP026649_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026649_8

2251286-2251875

Orphan

Consensus_repeat	Method
CGCTTCCTTAACNTAGAC	CRT

11 spacers

The CRISPR arrays of CP026649_8

>merge|CP026649|8|2251286-2251875|CRT
CGTTTCCTTAACTTAGAGGTCCTCTATGTGAAGGAAGAGCCTCGTTTTTGCTTGCTTCCTTAACGTAGACGCGCTCTACGTGAAGATAGACCGTCTTTTTTCCGCGCTTCCTTAACATAGACACGCTCTATGTTAAGGAACAACCTCAATTTCCTTCGCTTCCTTAACGTAGACGCACTCTATGTGAAGATAGACCGACTTTTTTCCGCGCTTCCTTAACATAGACACGCTCTATGTTAAGGAACAACTTCAATTTCCTTCGCTTCCTTAACGTAGACGCACTCTATGTGAAGATAGACCGACTTTTTTCCGCGCTTCCTTAACATAGACACGCTCTATGTTAAGGAACAACTTCAATTTCCTTCGCTTCCTTAACATAGACGCGCTCTATGTAAAGAAAGGACTCATTTTTTCCACGCTTTCTTAACGTAGACGGGCTCTAGGTTAAAGAAGAGGACCATTTTCCTTCGCTTCCTTAACATAGACGCGCCCTATGTGAAGAAAGGCTGCCTTTTTTCCACGCTTCCTTAACGTAGACGCACTCTATGTGAAGAAAGACCCTCAATTTCCCCCGCTTCCTTTACGTAGAC

>CP026649|8|4|2251286-2251875|CRT
CGTTTCCTTAACTTAGAG	GTCCTCTATGTGAAGGAAGAGCCTCGTTTTTGCT
TGCTTCCTTAACGTAGAC	GCGCTCTACGTGAAGATAGACCGTCTTTTTTCCG
CGCTTCCTTAACATAGAC	ACGCTCTATGTTAAGGAACAACCTCAATTTCCTT
CGCTTCCTTAACGTAGAC	GCACTCTATGTGAAGATAGACCGACTTTTTTCCG
CGCTTCCTTAACATAGAC	ACGCTCTATGTTAAGGAACAACTTCAATTTCCTT
CGCTTCCTTAACGTAGAC	GCACTCTATGTGAAGATAGACCGACTTTTTTCCG
CGCTTCCTTAACATAGAC	ACGCTCTATGTTAAGGAACAACTTCAATTTCCTT
CGCTTCCTTAACATAGAC	GCGCTCTATGTAAAGAAAGGACTCATTTTTTCCA
CGCTTTCTTAACGTAGAC	GGGCTCTAGGTTAAAGAAGAGGACCATTTTCCTT
CGCTTCCTTAACATAGAC	GCGCCCTATGTGAAGAAAGGCTGCCTTTTTTCCA
CGCTTCCTTAACGTAGAC	GCACTCTATGTGAAGAAAGACCCTCAATTTCCCC
CGCTTCCTTTACGTAGAC

Protein	Signature genes	Signature genes Name	Protein_function
CP026649.1\|AVD56697.1\|2259239_2259437_-\|50S-ribosomal-protein-L35	unknown	unknown	gnl\|CDD\|234676
CP026649.1\|AVD56694.1\|2256565_2257978_-\|O-antigen-ligase-domain-containing-protein	unknown	unknown	gnl\|CDD\|377422
CP026649.1\|AVD56686.1\|2248558_2248894_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367559
CP026649.1\|AVD56685.1\|2247870_2248566_-\|DUF1129-domain-containing-protein	unknown	unknown	gnl\|CDD\|368981
CP026649.1\|AVD56681.1\|2239638_2240064_-\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD56693.1\|2255647_2256139_-\|lactoylglutathione-lyase-family-protein	unknown	unknown	gnl\|CDD\|132684
CP026649.1\|AVD56691.1\|2253167_2254496_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|214599
CP026649.1\|AVD56683.1\|2243940_2244834_-\|DUF4405-domain-containing-protein	unknown	unknown	gnl\|CDD\|379580
CP026649.1\|AVD56695.1\|2258069_2258522_-\|dUTP-diphosphatase	unknown	unknown	gnl\|CDD\|234802
CP026649.1\|AVD56692.1\|2254646_2255633_-\|zinc-binding-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|176232
CP026649.1\|AVD56684.1\|2245341_2245680_+\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|225209
CP026649.1\|AVD56680.1\|2239399_2239612_+\|small-acid-soluble-spore-protein-SspI	unknown	unknown	gnl\|CDD\|179513
CP026649.1\|AVD56690.1\|2252364_2252919_+\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223508
CP026649.1\|AVD56688.1\|2249502_2250168_+\|7-cyano-7-deazaguanine-synthase-QueC	unknown	unknown	gnl\|CDD\|182967
CP026649.1\|AVD57861.1\|2259460_2260006_-\|translation-initiation-factor-IF-3	unknown	unknown	gnl\|CDD\|234582
CP026649.1\|AVD56698.1\|2260568_2261822_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
CP026649.1\|AVD56682.1\|2240065_2241427_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|379252
CP026649.1\|AVD56696.1\|2258852_2259206_-\|50S-ribosomal-protein-L20	unknown	unknown	gnl\|CDD\|179959
CP026649.1\|AVD56689.1\|2250216_2251149_+\|2-dehydropantoate-2-reductase	unknown	unknown	gnl\|CDD\|273247
CP026649.1\|AVD56687.1\|2249019_2249217_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP026649.1\|AVD56697.1\|2259239_2259437_-\|50S-ribosomal-protein-L35	gnl\|CDD\|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	2.27585e-22
CP026649.1\|AVD56694.1\|2256565_2257978_-\|O-antigen-ligase-domain-containing-protein	gnl\|CDD\|377422	pfam04932, Wzy_C, O-Antigen ligase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. This family includes O-antigen ligases such as E. coli RfaL.	4.73113e-08
CP026649.1\|AVD56686.1\|2248558_2248894_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|367559	pfam03551, PadR, Transcriptional regulator PadR-like family. Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.	5.50707e-24
CP026649.1\|AVD56692.1\|2254646_2255633_-\|zinc-binding-alcohol-dehydrogenase	gnl\|CDD\|176232	cd08271, MDR5, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	2.29525e-139
CP026649.1\|AVD56693.1\|2255647_2256139_-\|lactoylglutathione-lyase-family-protein	gnl\|CDD\|132684	TIGR03645, glyox_marine, lactoylglutathione lyase family protein. Members of this protein family share homology with lactoylglutathione lyase (glyoxalase I) and are found mainly in marine members of the gammaproteobacteria, including CPS_0532 from Colwellia psychrerythraea 34H. This family excludes a well-separated, more narrowly distributed paralogous family, exemplified by CPS_3492 from C. psychrerythraea. The function is of this protein family is unknown.	2.56858e-109
CP026649.1\|AVD56691.1\|2253167_2254496_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	4.80999e-46
CP026649.1\|AVD56683.1\|2243940_2244834_-\|DUF4405-domain-containing-protein	gnl\|CDD\|379580	pfam14358, DUF4405, Domain of unknown function (DUF4405). This presumed domain is functionally uncharacterized. This domain family is found in bacteria and archaea, and is approximately 50 amino acids in length. There are two conserved histidines that may be functionally important. This family is N-terminally truncated compared to other members of the clan.	5.74338e-10
CP026649.1\|AVD56695.1\|2258069_2258522_-\|dUTP-diphosphatase	gnl\|CDD\|234802	PRK00601, dut, dUTP diphosphatase.	5.25932e-72
CP026649.1\|AVD56684.1\|2245341_2245680_+\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	1.99476e-19
CP026649.1\|AVD56680.1\|2239399_2239612_+\|small-acid-soluble-spore-protein-SspI	gnl\|CDD\|179513	PRK02955, PRK02955, small acid-soluble spore protein SspI; Provisional.	6.54482e-32
CP026649.1\|AVD56685.1\|2247870_2248566_-\|DUF1129-domain-containing-protein	gnl\|CDD\|368981	pfam06570, DUF1129, Protein of unknown function (DUF1129). This family consists of several hypothetical bacterial proteins of unknown function.	8.95977e-13
CP026649.1\|AVD56688.1\|2249502_2250168_+\|7-cyano-7-deazaguanine-synthase-QueC	gnl\|CDD\|182967	PRK11106, PRK11106, queuosine biosynthesis protein QueC; Provisional.	8.66111e-125
CP026649.1\|AVD57861.1\|2259460_2260006_-\|translation-initiation-factor-IF-3	gnl\|CDD\|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	8.1251e-97
CP026649.1\|AVD56698.1\|2260568_2261822_-\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.13207e-51
CP026649.1\|AVD56682.1\|2240065_2241427_-\|IS4-family-transposase	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.31725e-16
CP026649.1\|AVD56696.1\|2258852_2259206_-\|50S-ribosomal-protein-L20	gnl\|CDD\|179959	PRK05185, rplT, 50S ribosomal protein L20; Provisional.	1.90481e-69
CP026649.1\|AVD56689.1\|2250216_2251149_+\|2-dehydropantoate-2-reductase	gnl\|CDD\|273247	TIGR00745, Putative_2-dehydropantoate_2-reductase, 2-dehydropantoate 2-reductase. This model describes enzymes that perform as 2-dehydropantoate 2-reductase, one of four enzymes required for the de novo biosynthesis of pantothenate (vitamin B5) from Asp and 2-oxoisovalerate. Although few members of the seed alignment are characterized experimentally, nearly all from complete genomes are found in a genome-wide (but not local) context of all three other pantothenate-biosynthetic enzymes (TIGR00222, TIGR00018, TIGR00223). The gene encoding this enzyme is designated apbA in Salmonella typhimurium and panE in Escherichia coli; this protein functions as a monomer and functions in the alternative pyrimidine biosynthetic, or APB, pathway, used to synthesize the pyrimidine moiety of thiamine. Note, synthesis of the pyrimidine moiety of thiamine occurs either via the first five steps in de novo purine biosynthesis, which uses the pur gene products, or through the APB pathway. Note that this family includes both NADH and NADPH-dependent enzymes, and enzymes with broad specificity, such as a D-mandelate dehydrogease that is also a 2-dehydropantoate 2-reductase. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A].	1.02358e-55
CP026649.1\|AVD56690.1\|2252364_2252919_+\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|223508	COG0431, COG0431, Predicted flavoprotein [General function prediction only].	1.02316e-43

>CP026649.1|AVD56689.1|2250216_2251149_+|2-dehydropantoate-2-reductase
MAEIKTVSIIGLGALGILFGHHLSKKMPAKNLRIIADQQRIERYEREGVYCNGEKCHFHYVTPEETVEPADLVLFTVKFNGLDEAVEAVKQHVGPDTVILSALNGISSEEIIGRTYGMDKMLYCVAQGMDAVKTGNQLTYAHMGMLCFGEKEPGLFSDKMKKVARFFEQTDLPYEADTEMMKRLWGKFMLNVGVNQTVAVYKSNYGEIQKDGPAREMMIAAMREVEALSEKEGFPLTEEDLRYWLKVVGNLSPAGKPSMAQDVEAKRYSEVGLFSGTVIKLGKKYGVQVPVNEELNRRIREIESTYTAVH
>CP026649.1|AVD56688.1|2249502_2250168_+|7-cyano-7-deazaguanine-synthase-QueC
MKKEKAVVVFSGGQDSTTCLFWAKKKFQEVEAVTFDYGQRHRLEIECAKNIAEELGVKQHILDMQLLNQLAPNALTRESITVKAGADGELPNTFVPGRNLLFLSFAGVLASQIGARHIVTGVCETDFSGYPDCRDIFIKSLNVTLNLSMDQQFVIHTPLMWRNKAETWALADELGAFDFVREKTLTCYNGIIADGCGECPACKLRKRGLEQYLAIRNGQSE
>CP026649.1|AVD56687.1|2249019_2249217_-|hypothetical-protein
MKRYVQLFFMFAVTVLIVMGIQKGLSTLNVLNLENFWANYVVFLILAYMILSFFLHYFSKRKKQS
>CP026649.1|AVD56686.1|2248558_2248894_-|PadR-family-transcriptional-regulator
MSIRSQLLKGILDGCVLAVIEKEPVYGYILSKKLQQLGLQEISEGTLYPVLLRLQKNGWIHGEMQPSDSGPSRKYYELTEKGKSALDEITAEWQRIAAPVNLLLKGRSEDA
>CP026649.1|AVD56685.1|2247870_2248566_-|DUF1129-domain-containing-protein
MLSVKQLIEENNRKRQELAPENKKFYNDMLDYLRLQTVLSEQQTEEVLMELLDHLLEGQKENKTAAQMFGGDPKAFADEIIRQLPKENKRNMVSFTIRIMILLLGIDLVINGITAFVVERFFSRPLPPFYPVPAALNFFIAGLYVIFAIWYIFRILKKSLFKEKTKKVQILTFLKIDAVIFVFLGGVILLDKFMPKIGPSFSYPWWLPLVLGVVSLGVYYSWEKAAKSRGI
>CP026649.1|AVD56684.1|2245341_2245680_+|antibiotic-biosynthesis-monooxygenase
MFVQLRRMTVAKGHADQVIERFSKPGIIEQQEGFVDIKIMQKKQGRGEEEVIVMITWESETHWKQWEKSDVHIAGHRANRGKSKPDYMLNMELGMYEVKAVKKAAGKAEISE
>CP026649.1|AVD56683.1|2243940_2244834_-|DUF4405-domain-containing-protein
MCRGGAEDEKNYAKFAIDLFMAIMFVLFFNKNVLGGLAYHEIAGLVFGVVFLTHVCLNLNWVKNVTLKMFDKRLPWKARGSYALNLLLLISMCFIIISGIIISRVVFPNINLGNEGWFKTTHISVSFLVLILVGVHVGLHWHWVVNVFKRMVHFKAKNKWAGYVAKVAATLILVFSSCEIIQTGFLNRMASAASIFGGSTGNSEMEGHHDFNGKSGQKSDFTNGQRLDFTNGQKPAFANEKKPDFADGDRRGGGDHDGGSANVLTVLLTYTGIMSAFVVLTYYLRKLTVRKKRRKTA
>CP026649.1|AVD56682.1|2240065_2241427_-|IS4-family-transposase
MIDQNCQYNQLPKELDSVFSELEMKKHLRHAGIKKSFGFSCSYLFQLVFCLIFQHKNWFSLLESKKADQFPAKDAVYRFLNQSTFNWRQFLLLLSTFTIRKVERLTDKSRPKVFIVDDSSFYRNRSQKVELLARCFDHASLKMRFYKGFRMLTLGWSDGYTFMPIDFSLLSSKKAQINGISEQIDKRTCGYKRRKNALQSEPEQIPSMLKRALASGINASYVLMDSWFTLPPLVKAIVEQGLDVIGMVKETKQRYNVDGKLVSLKQLYRLAQPLQSKKGILRSIRTVMANGTPVKVIFVQNRNKKSEWLALLSTDCTLSEQEIVRIYGMRWDIEVFFKTTKSLLKLEKELQSRSYDGLISHTTIVFARFIVLSWQNRCNTDQRTIGRLFYELCDEVNELDWAVALQQLIELLQDALKQTNKRFKKLIQSQLEQWISGLPSYIKAYLPISLCES
>CP026649.1|AVD56681.1|2239638_2240064_-|hypothetical-protein
MKEKDFVAFLTEAGRYDKTAEKCTVCGIILPSFSDYLLRGPAGALGTKYNVLSYSEQGLTVIPINNITGNMLPDESAFIPGEKITSMKTVPKLTYHRLYVGTSDGTAVFRLNKVLIGYGWHKRNLPSFIATVNGLEEPVHI
>CP026649.1|AVD56680.1|2239399_2239612_+|small-acid-soluble-spore-protein-SspI
MDLDLRKAVIHNVKEDTQDQLKDTIVDAIQRGEEKMLPGLGVLFEVIWNHADTQEQKMMLETLEQGLSQA
>CP026649.1|AVD56690.1|2252364_2252919_+|NAD(P)H-dependent-oxidoreductase
MTKVGILLGSLRKASFSRKLAENVANLFPEGYETEFVEIGNLPLYNQDFDDHNQVPAEYTTFRNTVKGLDAVLFVTPEYNRSIPAVLKNAIDVGSRPYGQSIWDGKPAAIISQSPGNLSGFGANHHLRQSLVCLNMPILQQPEAYIGNVTALFDENGKIVNEGTVRFLQSFTDAFVDLIKKYKG
>CP026649.1|AVD56691.1|2253167_2254496_+|methyl-accepting-chemotaxis-protein
MLKNVKKISFKIIMLSVLNSVIVIAINIGASVYGNIGKGNSGTGNHVPPAGIAIIPTNVLIGLFISLIIGIILSYILGRVISKPILQTAELAEQTAALDLREENGSFDKIQSFQDETGKLARALRQTRISLREVAKRLKEFSSKVATHTDTLSKRTEESFQSINQVASSIDEFAQGNSQLSETVHDINKTLNEVINLIETITQEAANGAEHAAASLDAVKEGQNTIDHQFKKIDQNIEITATANESITELSGMIDQVQAFVNVITSIAEQTNLLALNASIEASRAGDAGRGFAVVAGEIRKLAEGSSKAAREIKDLIATTTKKSNAAVENISKANAFIHEQKDAFHKTEAAFHQIQHTYSNIVGSFQHTAEGIETINEKSKQISKRIQEITSTVENFAASSEEMSASGQEQRAFTEIISQSAKELQELAGKLDAEMNKFKVS
>CP026649.1|AVD56692.1|2254646_2255633_-|zinc-binding-alcohol-dehydrogenase
MKGWLIGKPASIDDLTWGEVPDPRAGEGQLVVKVMSTALNPVDYQLIESGNPNWVYPHITGVDLAGEVVEVGPDTSGFKTGDRVACHTDLNRKGAFAQFAAIDANAAAKIPDGVSYDEAVAVLCAGMTAYQAVVQKLNHTDKQTILIHAGAGGVGGFAIQLAKELGLKVFTTASAANHEWVKSLGADTAIDYHTEDVTKRIMEETDGEGVDLILNTVSSAEATEDLKRLTFSGQLAYIAGAPDLSGIKPFTLAPSIHEVALGAAHASGSVRAKQNLAYMAGELMQRVKKGTLNAMVNQVLPREELPAGLKTLKGRHVRGKIIVRMHEA
>CP026649.1|AVD56693.1|2255647_2256139_-|lactoylglutathione-lyase-family-protein
MTYPRSFSHIGLSVPNLDKAVQFYTEVMGWYVIMEPSEIKEDDSAIGIMCKDVFGSGWGSFRIAHLAMGDGTGVEMFEFKNNETPDNNFEYWKTGIFHYAVQDPDVEGLVEKIKAHGGKQRMPIREYYPGKKPYRMVYCEDPFGNLVEIYSHSYELTYSEGAY
>CP026649.1|AVD56694.1|2256565_2257978_-|O-antigen-ligase-domain-containing-protein
MNSLIHFIKEHAFELAAVLCFALPPVGLFIMLVFSLSELYRHIKNKRLFSSSPVSFFFLCLLVATTGAAVQMGEPLLLAESLRILFYWGIFLKIMGSGTRGRFKQFRWIVIGCGLYGIFIGWLPKMLSDDPVLAFLTGTELFGFKHYNRLIGSTYNPNFTMFLLLVGISFLFVEMLKDAGKKDWKNMSWKCIPLFFLSKGVFDTGSRAGFISMICIYFIFFFRWNKWIFGGGLLFLALGAGKLAAVIPRVHSIEGSLTGREKIWYHSYKIFETHFLFGTTPLGFGKVYASLFHKNIYHAHDIFIGFFVEYGAIGGIAFLAVLVMGMFKLGRLFFIKRNYRYLNIFLLSLPVIVLTGFLDEPVFSPQIGMLAVVLLSYWEWYSKRMFQPHVAFLNRLNVKRNVLKRQLPKPELQSISRAITGEIKAIESVVHETAEPFEICKKEVRNNRGKPDEKTPDKELSDKTPDKENE
>CP026649.1|AVD56695.1|2258069_2258522_-|dUTP-diphosphatase
MDDVLKVKLLHPDAQLPQRANPGDAGLDLYSIEEKNIAPGEAELIRTGIAIELPRRTEAQVRPRSGLALKHRVTVLNSPGTIDEGYRGEIKVILINFGKTPFKVEKGMRIAQMIIAPVMSVTVSVTEQLAESERGEGGFGSTGIAKINEK
>CP026649.1|AVD56696.1|2258852_2259206_-|50S-ribosomal-protein-L20
MPRVKGGTVTRRRRKKVLKLAKGYYGSKHTLFKVANQQVMKSYMYAYRDRRQKKRDFRKLWITRINAAARINGLSYSRLMHGLKQAGIEVNRKMLADLAVNDAQAFAELANKAKAAL
>CP026649.1|AVD56697.1|2259239_2259437_-|50S-ribosomal-protein-L35
MPKMKTHRGSAKRFKKTGSGSLKRSHAYRSHLFANKVTKQKRQLRKSTLVSESDMKRIRQMLDNL
>CP026649.1|AVD57861.1|2259460_2260006_-|translation-initiation-factor-IF-3
MKLSWRWLIISKDMMVNEGIRAREVRLIGQNGEQMGVKSRNEALEIAARANLDLVLVAPNAKPPVARIMDYGKYRFEMQKKDREARKKQKIINVKEVRLSPTIEEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKDIGQRVLDRFAEACAEVATVESKPKMDGRSMFLVLAPKTEKK
>CP026649.1|AVD56698.1|2260568_2261822_-|MFS-transporter
MDLFRNRHFNALFFGRLFTNIGDSVYYIAMMWMVLKLGGNSTVYTGFAGFLFSMTEVLSLFYGPVLDKINAKKLLVTASFLQAGLLLFLVVLSKSGIMNVWLLLLSIPVLSFLSELTYPLESVLLPKAVEKKDLVKANSLMSIAYKGSDFFFNGIAGFILAAFSMSMVLGMNSLLFILSSILFLFLKVQVKRSKQTGSVREEWQAYKRDFKEGLSFVKQPFILQLLIPLLFLNFFFAIVMVVLPSFANTAGEGASSYGIMTAALGLGALAGAAGADKISRIFPFGKILAAGFLLSGLSWLFMILLSNVSIWYVYTLMFISELSIGAINVLFSAIFQQLPDEQMLGRVNTINVSLLSLAMPAGSLIGGVMAKITSVQLTMSFFGIGLFVLALFYMGSGRMRKLPKVVEIDHTYVKLSR

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Crispr_ID: CP026649_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026649_9

2398925-2399005

Orphan

Consensus_repeat	Method
CTTTGCGAGATCCAATTCGCAAATGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026649_9

>merge|CP026649|9|2398925-2399005|CRISPRCasFinder
CTTTGCGAGATCCAATTCGCAAATGGGGGCGTTTTTCCCAAAACCCGTTCGTTCGCTTTGCAAGATCCAATTCGCAAATGG

>CP026649|9|5|2398925-2399005|CRISPRCasFinder
CTTTGCGAGATCCAATTCGCAAATGG	GGGCGTTTTTCCCAAAACCCGTTCGTTCG
CTTTGCAAGATCCAATTCGCAAATGG

Protein	Signature genes	Signature genes Name	Protein_function
CP026649.1\|AVD56807.1\|2386091_2387186_-\|DUF2600-domain-containing-protein	unknown	unknown	gnl\|CDD\|378492
CP026649.1\|AVD56808.1\|2387196_2388003_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|225176
CP026649.1\|AVD56826.1\|2409285_2409444_+\|DUF1540-domain-containing-protein	unknown	unknown	gnl\|CDD\|377869
CP026649.1\|AVD56814.1\|2395462_2396515_-\|DUF2584-domain-containing-protein	unknown	unknown	gnl\|CDD\|224423
CP026649.1\|AVD56811.1\|2391176_2392388_-\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
CP026649.1\|AVD56819.1\|2404898_2405705_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
CP026649.1\|AVD56809.1\|2388161_2388677_+\|gamma-carbonic-anhydrase-family-protein	unknown	unknown	gnl\|CDD\|100051
CP026649.1\|AVD56821.1\|2406869_2407118_+\|DUF1836-domain-containing-protein	unknown	unknown	unknown
CP026649.1\|AVD56812.1\|2392852_2394442_+\|phosphoenolpyruvate-carboxykinase-(ATP)	unknown	unknown	gnl\|CDD\|376517
CP026649.1\|AVD56816.1\|2397281_2398817_+\|gluconokinase	unknown	unknown	gnl\|CDD\|130381
CP026649.1\|AVD56818.1\|2404141_2404912_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213260
CP026649.1\|AVD56813.1\|2394592_2394982_-\|DNA-mismatch-repair-protein-MutT	unknown	unknown	gnl\|CDD\|240040
CP026649.1\|AVD56824.1\|2408084_2408213_+\|DUF4021-domain-containing-protein	unknown	unknown	unknown
CP026649.1\|AVD56817.1\|2400737_2402153_-\|ISLre2-family-transposase	unknown	unknown	gnl\|CDD\|284250
CP026649.1\|AVD56825.1\|2408332_2409223_+\|adhesin	unknown	unknown	gnl\|CDD\|238499
CP026649.1\|AVD56820.1\|2406236_2406701_-\|nucleoside-triphosphatase-YtkD	unknown	unknown	gnl\|CDD\|131752
CP026649.1\|AVD56815.1\|2396521_2397064_-\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
CP026649.1\|AVD56822.1\|2407190_2407640_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
CP026649.1\|AVD56823.1\|2407756_2407993_+\|membrane-protein-insertion-efficiency-factor-YidD	unknown	unknown	gnl\|CDD\|178815
CP026649.1\|AVD56810.1\|2389047_2390946_-\|asparagine-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|223444

Protein	Function_ID	Function_description	E-value
CP026649.1\|AVD56807.1\|2386091_2387186_-\|DUF2600-domain-containing-protein	gnl\|CDD\|378492	pfam10776, DUF2600, Protein of unknown function (DUF2600). This is a bacterial family of proteins. Some members in the family are annotated as YtpB however currently no function is known.	0
CP026649.1\|AVD56808.1\|2387196_2388003_-\|alpha/beta-hydrolase	gnl\|CDD\|225176	COG2267, PldB, Lysophospholipase [Lipid metabolism].	3.67526e-69
CP026649.1\|AVD56826.1\|2409285_2409444_+\|DUF1540-domain-containing-protein	gnl\|CDD\|377869	pfam07561, DUF1540, Domain of Unknown Function (DUF1540). This family has four conserved cysteines, which is suggestive of a metal binding function.	8.61231e-10
CP026649.1\|AVD56814.1\|2395462_2396515_-\|DUF2584-domain-containing-protein	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	2.41543e-50
CP026649.1\|AVD56811.1\|2391176_2392388_-\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
CP026649.1\|AVD56819.1\|2404898_2405705_+\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	2.21467e-66
CP026649.1\|AVD56809.1\|2388161_2388677_+\|gamma-carbonic-anhydrase-family-protein	gnl\|CDD\|100051	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism, involving the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed by the regeneration of the active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. They are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionary distinct groups - alpha, beta and gamma carbonic anhydrases - which show no significant sequence identity or structural similarity. Gamma CAs are trimeric enzymes with left-handed parallel beta helix (LbH) structural domain.	2.55616e-77
CP026649.1\|AVD56812.1\|2392852_2394442_+\|phosphoenolpyruvate-carboxykinase-(ATP)	gnl\|CDD\|376517	pfam01293, PEPCK_ATP, Phosphoenolpyruvate carboxykinase.	0
CP026649.1\|AVD56816.1\|2397281_2398817_+\|gluconokinase	gnl\|CDD\|130381	TIGR01314, gntK_FGGY, gluconate kinase, FGGY type. Gluconate is derived from glucose in two steps. This model describes one form of gluconate kinase, belonging to the FGGY family of carbohydrate kinases. Gluconate kinase phosphoryates gluconate for entry into the Entner-Douderoff pathway. [Energy metabolism, Sugars].	0
CP026649.1\|AVD56818.1\|2404141_2404912_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213260	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters. NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	5.17567e-113
CP026649.1\|AVD56813.1\|2394592_2394982_-\|DNA-mismatch-repair-protein-MutT	gnl\|CDD\|240040	cd04684, Nudix_Hydrolase_25, Contains a crystal structure of the Nudix hydrolase from Enterococcus faecalis, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	1.40989e-06
CP026649.1\|AVD56825.1\|2408332_2409223_+\|adhesin	gnl\|CDD\|238499	cd01017, AdcA, Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).	1.94198e-97
CP026649.1\|AVD56817.1\|2400737_2402153_-\|ISLre2-family-transposase	gnl\|CDD\|284250	pfam06782, UPF0236, Uncharacterized protein family (UPF0236).	7.12188e-48
CP026649.1\|AVD56820.1\|2406236_2406701_-\|nucleoside-triphosphatase-YtkD	gnl\|CDD\|131752	TIGR02705, conserved_hypothetical_protein, nucleoside triphosphatase YtkD. The functional assignment to the proteins of this family is contentious, with papers disagreeing in both interpretation and enzyme assay results. This protein belongs to the nudix family and shares some sequence identity with E. coli MutT but appears not to be functionally interchangeable with it. [DNA metabolism, DNA replication, recombination, and repair].	1.95958e-54
CP026649.1\|AVD56815.1\|2396521_2397064_-\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	2.28697e-28
CP026649.1\|AVD56822.1\|2407190_2407640_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	2.37612e-59
CP026649.1\|AVD56823.1\|2407756_2407993_+\|membrane-protein-insertion-efficiency-factor-YidD	gnl\|CDD\|178815	PRK00041, PRK00041, hypothetical protein; Validated.	2.01477e-41
CP026649.1\|AVD56810.1\|2389047_2390946_-\|asparagine-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|223444	COG0367, AsnB, Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism].	0

>CP026649.1|AVD56816.1|2397281_2398817_+|gluconokinase
MTYYLGVDIGTTTTKSVLFGEKGKVISMHHAGYPLYSPSPQVAEQNPDEIFRAVIDSMKTAIVKSDIDPSEIKLVSFSSAMHSLIAVDKDGKPLTNCITWADARAAKWAKKIKDEWHGQDIYRRTGTPIHPMSPLSKITWLRHEEQELFKKTFKFIGIKEYIFYRFFGQYVVDYSLASATGLFNLHDLDWDKEALHVAGITADKLSKPVPTTFSLTGLAPEYAVETGIPQDTPFVAGASDGVLSNLGVNAIDPGVVAITIGTSGAIRTVTDKPVTDPKGRIFCYALTENHWVVGGPVNNGGMTFRWVRDELAAAEVETAKRLGIDPYEVLTKIAARVAPGSDGLIFHPYLAGERAPIWNADARGSFFGLGLHHKREHMVRAVLEGVIYNLYTVMLALQEMIGIPKKIQATGGFARSDLWRQMLADIFNQEVVVPESFESSCLGAIVLGMYALDEIDDFSVVSDWIGATHTHRPIPENTAVYEEILPIYIRISRLLEGEYTNIAAFQRKWVK
>CP026649.1|AVD56815.1|2396521_2397064_-|flavodoxin-family-protein
MTIAVIYGSSRPRGNTEMLTERAVEGMHVERFYLKDAHILPIEDKRHTDSGFSKVEDDYSILIQHIFMCDTIIFATPIYWYGMSGLMKNFIDRWSQTLRDPQFPDFKKRMAEKKIYVIAVGGDMPRVKGLPLIQQFAYIFDFLGMRFDGYILGEGNKPGDIVQDKEAIFAADQLNEALKR
>CP026649.1|AVD56814.1|2395462_2396515_-|DUF2584-domain-containing-protein
MKTVIEKQLFPSPNPHVRMYLVTYWSDGLKVKGLLAEPDDGRVYDGFLYLRGGIKSVGMVRPARIGEFASEGFIVFAPFYRGNWGGEGDEDFGGDDMHDAYFGFDVLMEHERVSGRVHVFGFSRGGIMALGTAEARPAASIVTWGGVSDVALCYAERVDLRKMMKRVIGGTPDKYPERYRVRTPLYKLGQIGCPVLVIHGEKDQNVSVEHAIRLEHGLKQLGKSVETWYFPELGHHFPPPVNRRVVHAASVWMKRHSAHDTIEATTEVSRMGMPMELDTMLVTNGKEERIEQNLFLLKQPGYCVYPLDTPVEIRKKKEHGPSGSAVIRKLEWENNTTIVHYELVSLNTPN
>CP026649.1|AVD56813.1|2394592_2394982_-|DNA-mismatch-repair-protein-MutT
METDYKKACGAYAVIFDAKKEKVGVVPSGSGYRLPGGEISRGESELACLMRTVGAELEIAGFLGKAAQETGARSMDEGLFYLGKWEQPRKGSHNLEWLNLHEAVEKMAGAHHQWAVQEGISAVQTSTWF
>CP026649.1|AVD56812.1|2392852_2394442_+|phosphoenolpyruvate-carboxykinase-(ATP)
MKMDLIGASDDLKFLLSGENVRMQLSVPQLMEKIIERKEAVLTTEGAISAATGKYTGRSPKDKFIVVDSESKDRVDWGKINQPVSPGVFNRLYEKMVRHLKGKDEIFVFKGFAGADPKSRLPIQTVNEFAWHNLFAHQLFIRPDAEELYQHDAQFTILSAPLFKADPALDGTHSEAFIMISLERRIILIGGTEYAGEMKKSIFSIMNYLLPQKGILPMHCSANTGKNGDTALFFGLSGTGKTTLSADPERALIGDDEHGWSDSGVFNIEGGCYAKCIGLTEEKEPQIYQAIRFGTVLENVVVDPVSRKPQYDNNALTENTRAAYPIENIGNIARSGMAGHPSTIIFLTADASGVLPPISRLTKEQAMYHFLSGYTSKLAGTERGVTRPEAVFSTCFGAPFLPLEPAVYAEMLGEKVDRHNVQVFLVNTGWTGGPYGTGSRMKLSDTRAMVRAAINGKLKDTETRQDDIFGLHIPVHIEGVSDDVLYPADTWTDKQAYREKAFELAARFKENFRQFSVPDDIEKLGGPLI
>CP026649.1|AVD56811.1|2391176_2392388_-|methionine-adenosyltransferase
MLKGRHLFTSESVTEGHPDKICDQISDAILDAILEKDPNARVACETSVTTGLVLVTGEISTNTYVDIPKVVRKTIKEIGYTRAKYGFDAETCAVLTSIDEQSEDIARGVNQALEAREGGMSDEEIEAIGAGDQGLMFGFACNETEELMPLPISLAHKLARRLAELRKQEVIPYLRPDAKTQVTVEYDENNQPARIDTIVISTQHDPDTSAGQIQEDMKKYVIEPVVPAHLLDADTKYLINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARYVAKNIVAAGLAEKCEVQLAYAIGVAKPVSISIDTFGTGKVPEKVLIEAVEAHFDLRPAGIIKMLDLRRPIYRQIAAYGHFGRDDLDVPWEKTDKAGALNEFARNHIGK
>CP026649.1|AVD56810.1|2389047_2390946_-|asparagine-synthase-(glutamine-hydrolyzing)
MCGFIGCVHDHPVTLSDEDRQQFKQMNHMIEHRGPDDEGFYEDEHIQFGFRRLSIIDIEAGHQPLTYENERYWIIFNGEIYNYVELREELLKEGMTFETNSDTEVILAMYSRYGEKAIGRLRGMFGFAIWDKQEQTLCGARDPFGIKPFFYYEDGDKMYFGSEKKSILLAMEKPELNYDAVQYYLTYQFVPEPFTMTKDIRKLEPGHYFVKKIGKPMEIKRYWKASFHPVHKSEDEFIQEVRDVMIDSVKVHMRSDVPVGAFLSGGIDSSITASIAKQFHPGIKTFSVGFERDGYSEIDVAKETAEKLGVENISYVITPEEYMKELPKIIWHMDDPLADPACVPLYFVAREARKYVTVVLSGEGADELFGGYNIYREPQSLEVFDKIPAAGKSILKALAKVLPEGVKGKSFIERGVTPMEDRYIGNAKMYTEEEKRDLLLTYNNSLDYRDITKPLYNETKGYDPVNRMQYIDIHTWMRGDILLKADRMTMAHSLELRVPFLDKEVFRVASQIPASLKTSHNTTKYVLRKAAEGIVPEHVLNRKKLGFPVPIRHWLKDEMHDWAAEIIKTSPTDDIINKQYVLKLLEDHCAGKLDYSRKIWTVLIFMLWHAVYMEDKYDFQKGAQGRLAGASL
>CP026649.1|AVD56809.1|2388161_2388677_+|gamma-carbonic-anhydrase-family-protein
MIYAYNGKTPLIAPTAYIADNVTVTGDVEIGDESGIWFGTVIRGDVAPVKIGQKVNVQDNCVLHESPQTPLILEDEVTVGHQVILHSCHVRTKALIGMGSIILDGAEIGEGAFIGAGSLVTPGKKIPPHTLAFGRPAKVIRELTEKDIQDMRRIVREYAEKAQYYKNSVGR
>CP026649.1|AVD56808.1|2387196_2388003_-|alpha/beta-hydrolase
MWKWEADENPKAVIVIVHGAMEHHRRYSWLIEMWRSSGYHVVMGDLPGHGMTSRAKRGHIDSFDEYTTEIKEWVTAAYQFDLPIFLLGHSMGGLAVIRLLEQEHLKIAGVILSSPCLGLVQYPSKLLGLLSIGLNRIAPGLRFNSPLTVQMATRNKDIQMQAVNDSLMLTKVSVRWYRELLAAMRQAQMDTVRLPDVPFLVMQAGNDKIVDKGAVVNWFNQTSVSEKLYKEWPKCYHEIFNEPEREDVFLYAKNFVENRLRTLGYILE
>CP026649.1|AVD56807.1|2386091_2387186_-|DUF2600-domain-containing-protein
MTIPSYPISLMAQVYRRVMPAVHRELHYWREKARQIPNDELKTQALASIQHKTFHCEGGSILGLLAMEERTAAFRFIVAYQTISDYLDNLCDRSTSLDPVDFRALHESMSDALTVGAPLKNYYRYRLDQDDGGYLHELVRTCQVVLSRIPQYKAIQPYLLELCRYYSDLQVHKHVRVEERVPRLKEWFLRYKPDFPDMEWYEFSACSGSTLGIFCLVSYALRDDFRPEYATIIRDGYFPYIQGLHILLDYFIDQDEDKKGGDLNFCFYYPSEEELFKRLKHFLQEADKHTARLPNEKFHKLINRGLLAVYLSDEKVKKQRSVQKLSRKMIKFAGSISLFFYFNGKMYRAIKNMIPASLAKTIVK
>CP026649.1|AVD56817.1|2400737_2402153_-|ISLre2-family-transposase
MDIISIIAGLLKDTKSLIEFEEQLKLLMQKAFTQWVGEIFEELDKTIKQEKLEEGWVYCRSDNRNIQFLFGSVTFKRSLMHDKRGNSHYPLDEWLGLVPHQRYSPLVELKVAELASENTYREVADILKEWTAVSLSHTTVGNMVKHVGKTQAEADKALVEELEIAVSLPEGKKVDYLFSEADGVFVRGLKKKQSMEVHHAILYEGWETNGKRVSLRQPTVIMTTEDIQTFWDEVQATAANTYSLEKTHVITNSDGGAGYTAERFQTAFSQSEFPVLNQLDTYHVAQAIIRTFGGGKSEIKEQIRKAIRTHDLDQFTLYLDTHESTLTDKKALKKIKEFRSYILKNWDRIFDWRDRVKNVPEGARGLGAMESNQRHISFRMKKRGMHWSELGAEAMVKIKQGILNGTLREAYLKHRSRSERKQRNLKQFIRMSQLLKQPVRPSVGVKHGSVALHSSSSSAMGHLSKILELSF
>CP026649.1|AVD56818.1|2404141_2404912_+|ABC-transporter-ATP-binding-protein
MHFLTVQNVNHTYFTAKQATKALENISFQMEEGEFVSLLGPSGCGKTTLLSILAGLLQPTAGIVQIDGKLPGSRQSSIGYMLQQDYLFPWKTIEENIMIGLKLEKRLNPESRKHALGLLQTIGLAGTEKQYPRQLSGGMRQRAALVRTLAVDPKILLLDEPFSALDFQTKLKLEDLVFDTLKQFHKTAVLVTHDIGEAIAMSDRILLLASKPGRLYKIFDVPTELRRLRPFEARSQKIYSELFNDIWKELESLENS
>CP026649.1|AVD56819.1|2404898_2405705_+|ABC-transporter-permease
MKTAENTALRHEDYLAAMRKEKRRVRFFQLFILIVFFCLWEVASRLHWIDPLIFSSPSKVWALLVAKLEDGSLYVHLGITVFETVMGFILGTVLGAALAAVLWWSPFLSKILDPYLVVLNAMPKVALGPILIVSMGPGFSSIVAMGVIISVIVTTIVIYTAFRDVDPNYTKVLHSFGASRLQVFREAIFPASIPVIISTLKVNVGLAWVGVIVGEYLVSSKGLGYMIIYGFQVFNFTLVMLSMILIAIVATIMYQLVGWLEKKLVKDR
>CP026649.1|AVD56820.1|2406236_2406701_-|nucleoside-triphosphatase-YtkD
MYRFTDLNGNPVTFIFEKNAFPIEPQHVLVLARYRGNWLLTRHPKRGLEFPGGKREAGETVREAAERELYEETGGIPENLQYIGEYCVDDQVRGPFVKAVFYADIGRLETKHDYLETDGPVLVEGDLVEKLQSSSFSFLMKDGVVETALRHVEK
>CP026649.1|AVD56821.1|2406869_2407118_+|DUF1836-domain-containing-protein
MRLVDELFELYRDRLTGDEEDLDAISAAVVENYNRKDLLGIVREMSTAELEHFIGLYILETLKDKFSDYAGFDAYPTTKYLQ
>CP026649.1|AVD56822.1|2407190_2407640_-|DNA-starvation/stationary-phase-protection-protein
MAENEQLMEILNKQVANWTVLYTKLHNYHWYVKGPNFLSLHAKFEELYNLANDYLDELAERLLALNGNPVATLKGSLELSSVQEASGNESTEEMVQATANDFAMIAKELEEAIGLANRIGDDATADMFINIQETLDKNIWMLNAFLGRR
>CP026649.1|AVD56823.1|2407756_2407993_+|membrane-protein-insertion-efficiency-factor-YidD
MLKFIFIKLIRFYQLAISPLFPPSCRFQPTCSNYGLEAVKRFGALRGGYLAIRRILKCHPFHAGGYDPVPDQWPVKKH
>CP026649.1|AVD56824.1|2408084_2408213_+|DUF4021-domain-containing-protein
MFFMEEKKEQQKKSGDFGADPDEQAINGDYGMLETEEEDKKD
>CP026649.1|AVD56825.1|2408332_2409223_+|adhesin
MKKLFPVLLAFTMLFVTACANKQESKQDHKISVYTTVYPLEYVTQQIGGKYVSVKTIYPPGTDEHTYEPSQKDILKLADSDFFFYIGLGLEGFANKAKQVLEGQNVKMMALGDRLPVPDKTSTKADPHVWLDPIYVKQMAGMITTQLSKKMPKQKTYFKKNYAQLAKKLDQVNAAYKQAVEKSDNKELVVSHAAYGYWVKRYGIKQIPIAGLSTSDEPSQKQLENIIQKVKQDHISYIVFEKNVPSKIAEVVQQETNTKAVYIHHLGVRTNAEIKAHKDYFTLMDDNLKALEKALQ
>CP026649.1|AVD56826.1|2409285_2409444_+|DUF1540-domain-containing-protein
MAKDVLCEVRNCVFWEEGNLCSAEEIYIVSHTGTQAENQRETDCKTFESMFS

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Crispr_ID: CP026649_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026649_10

2419374-2419474

Orphan

Consensus_repeat	Method
GCGGGTGATGGGAATCGAACCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026649_10

>merge|CP026649|10|2419374-2419474|CRISPRCasFinder
GCGGGTGATGGGAATCGAACCCACGACAACAGCTTGGAAGGCTGTGGTTTTACCACTAAACTACACCCGCAGCAAAGGGCGGATGATGGGAATCGAACCCA

>CP026649|10|6|2419374-2419474|CRISPRCasFinder
GCGGGTGATGGGAATCGAACCCA	CGACAACAGCTTGGAAGGCTGTGGTTTTACCACTAAACTACACCCGCAGCAAAGG
GCGGATGATGGGAATCGAACCCA

Protein	Signature genes	Signature genes Name	Protein_function
CP026649.1\|AVD56837.1\|2432046_2432292_-\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD56840.1\|2434165_2435290_-\|DUF1646-domain-containing-protein	unknown	unknown	gnl\|CDD\|285138
CP026649.1\|AVD56827.1\|2409814_2410918_-\|o-succinylbenzoate-synthase	unknown	unknown	gnl\|CDD\|239433
CP026649.1\|AVD56831.1\|2417951_2418875_+\|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	unknown	unknown	gnl\|CDD\|235695
CP026649.1\|AVD56836.1\|2431864_2432044_-\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD56838.1\|2432344_2433250_-\|EamA/RhaT-family-transporter	unknown	unknown	gnl\|CDD\|223769
CP026649.1\|AVD56830.1\|2414604_2416350_-\|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase	unknown	unknown	gnl\|CDD\|236020
CP026649.1\|AVD56824.1\|2408084_2408213_+\|DUF4021-domain-containing-protein	unknown	unknown	unknown
CP026649.1\|AVD56839.1\|2433340_2434030_+\|MgtC/SapB-family-protein	unknown	unknown	gnl\|CDD\|224204
CP026649.1\|AVD56834.1\|2428725_2429376_-\|bacteriocin-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|188353
CP026649.1\|AVD56829.1\|2413804_2414608_-\|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase	unknown	unknown	gnl\|CDD\|274729
CP026649.1\|AVD56833.1\|2427234_2428398_+\|glycosyltransferase-family-1-protein	unknown	unknown	gnl\|CDD\|340831
CP026649.1\|AVD56835.1\|2429377_2431567_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273736
CP026649.1\|AVD56828.1\|2412945_2413764_-\|1,4-dihydroxy-2-naphthoyl-CoA-synthase	unknown	unknown	gnl\|CDD\|180958
CP026649.1\|AVD56825.1\|2408332_2409223_+\|adhesin	unknown	unknown	gnl\|CDD\|238499
CP026649.1\|AVD56823.1\|2407756_2407993_+\|membrane-protein-insertion-efficiency-factor-YidD	unknown	unknown	gnl\|CDD\|178815
CP026649.1\|AVD56826.1\|2409285_2409444_+\|DUF1540-domain-containing-protein	unknown	unknown	gnl\|CDD\|377869
CP026649.1\|AVD57866.1\|2416351_2417686_-\|isochorismate-synthase	unknown	unknown	gnl\|CDD\|224091
CP026649.1\|AVD56841.1\|2435799_2436186_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
CP026649.1\|AVD56832.1\|2426759_2426945_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP026649.1\|AVD56841.1\|2435799_2436186_-\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	1.05771e-06
CP026649.1\|AVD56840.1\|2434165_2435290_-\|DUF1646-domain-containing-protein	gnl\|CDD\|285138	pfam07854, DUF1646, Protein of unknown function (DUF1646). Some of the members of this family are hypothetical bacterial and archaeal proteins, but others are annotated as being cation transporters expressed by the archaebacterium Methanosarcina mazei.	1.567e-108
CP026649.1\|AVD56827.1\|2409814_2410918_-\|o-succinylbenzoate-synthase	gnl\|CDD\|239433	cd03317, NAAAR, N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building blocks for antibiotics, herbicides, and drugs. NAAAR is a member of the enolase superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.	0
CP026649.1\|AVD56831.1\|2417951_2418875_+\|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	4.94633e-126
CP026649.1\|AVD56830.1\|2414604_2416350_-\|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase	gnl\|CDD\|236020	PRK07449, PRK07449, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; Validated.	0
CP026649.1\|AVD56839.1\|2433340_2434030_+\|MgtC/SapB-family-protein	gnl\|CDD\|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	1.46137e-50
CP026649.1\|AVD56834.1\|2428725_2429376_-\|bacteriocin-ABC-transporter-ATP-binding-protein	gnl\|CDD\|188353	TIGR03608, L_ocin_972_ABC, putative bacteriocin export ABC transporter, lactococcin 972 group. A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate].	1.40778e-87
CP026649.1\|AVD56829.1\|2413804_2414608_-\|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase	gnl\|CDD\|274729	TIGR03695, menH_SHCHC, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase. This protein catalyzes the formation of SHCHC, or (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate, by elmination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Note that SHCHC synthase activity previously was attributed to MenD, which in fact is SEPHCHC synthase. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	8.56654e-120
CP026649.1\|AVD56833.1\|2427234_2428398_+\|glycosyltransferase-family-1-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	2.65403e-14
CP026649.1\|AVD56835.1\|2429377_2431567_-\|hypothetical-protein	gnl\|CDD\|273736	TIGR01654, unnamed_protein_product, bacteriocin-associated integral membrane (putative immunity) protein. This model represents a family of integral membrane proteins, most of which are about 650 residues in size and predicted to span the membrane seven times. Nearly half of the members of this family are found in association with a member of the lactococcin 972 family of bacteriocins (TIGR01653). Others may be associated with uncharacterized proteins that may also act as bacteriocins. Although this protein is suggested to be an immunity protein, and the bacteriocin is suggested to be exported by a Sec-dependent process, the role of this protein is unclear. [Cellular processes, Toxin production and resistance].	6.0006e-44
CP026649.1\|AVD56828.1\|2412945_2413764_-\|1,4-dihydroxy-2-naphthoyl-CoA-synthase	gnl\|CDD\|180958	PRK07396, PRK07396, dihydroxynaphthoic acid synthetase; Validated.	0
CP026649.1\|AVD56825.1\|2408332_2409223_+\|adhesin	gnl\|CDD\|238499	cd01017, AdcA, Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).	1.94198e-97
CP026649.1\|AVD56823.1\|2407756_2407993_+\|membrane-protein-insertion-efficiency-factor-YidD	gnl\|CDD\|178815	PRK00041, PRK00041, hypothetical protein; Validated.	2.01477e-41
CP026649.1\|AVD56838.1\|2432344_2433250_-\|EamA/RhaT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	4.0558e-13
CP026649.1\|AVD57866.1\|2416351_2417686_-\|isochorismate-synthase	gnl\|CDD\|224091	COG1169, MenF, Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	9.13781e-137
CP026649.1\|AVD56826.1\|2409285_2409444_+\|DUF1540-domain-containing-protein	gnl\|CDD\|377869	pfam07561, DUF1540, Domain of Unknown Function (DUF1540). This family has four conserved cysteines, which is suggestive of a metal binding function.	8.61231e-10

>CP026649.1|AVD56831.1|2417951_2418875_+|1,4-dihydroxy-2-naphthoate-polyprenyltransferase
MNAQSSPAIGPDKGWRIWWQLTRPHTLTAGFVPVILGTVLALGIARINLLLFAAMLVATLLIQAATNMFNEYYDYKRGLDTEHSVGIGGAIVRNGIKPKTVLHLAFAFFGAAMLIGVYICSQSSWWIAVIGTVCMLVAYLYTAGPFPISSTPLGELISGFFMGVIIILISFFIQTKTITWPIVFISIPIMILIGAIMLSNNIRDLDGDKANGRKTIAILLGRKGAILLLAAMFALSYLWMAGLVLFGVVTPWVLLVFVSTPKPVRAIKGFIGKSEPLQMLPAMKATAQTNTIFGVLLSISFLIDHFI
>CP026649.1|AVD57866.1|2416351_2417686_-|isochorismate-synthase
MKEKTAPALKLVSKVIKCRTAPDPLRLFTAGAAHFYGSRFFWQDADRETVFVGFGCVWSCTVTASDGFAQMEDEWRNLKGAGEVYSGTGETGTGPVLFGGFAFDGTVAKQEWKTFGQGIFRVPQILFTFKKDAVFLTVNGCGGTESVQEAEETARTLLNGSTAFLPALPLLKAVKEIGSDEWKKSVATAVEFIREGRMDKVVLARKLELAFDGVASPDAVLAALSAQQHDSYLFVLEEGSESFIGASPERLVKKTGRHILSTCLAGSIKRGRNEAEDLELGKALLSDQKNLSEHGFVVSMIRQVLEPFCNGLNVPDEPVLMRMRDIQHLYTPVTGTVKDKDTTLFQLVKALHPTPALGGIPRQPAMEAIRLLEKMDRGLYGAPIGWVDYRGSGEFCVGIRSGLLKEDRASLYAGCGVVKESEPEEEYKETSVKFTPMLRALGGK
>CP026649.1|AVD56830.1|2414604_2416350_-|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase
MEHQEIMTTYLAAFIRQLSAMGIRYAVVSPGSRSTPIAMLLAEHPDFQIYMDIDERSAAFFALGLAKEKRKPVVLLCTSGTAAANYYPAVAEANISRVPLIVLTADRPHELRNVGAPQAIDQIRLYGTHVKWFEEMPLPEAEEEVLQFVRQTAARAVVTALQQPAGPVHLNFPLREPLVPVLKPSPFAGEVPVPAIENFSGTLRLSEETVEIVAKEIREKDRGLIICGPIDIPGFAEAVVALSEKTGYPVLADPLSQLRSGRHGKERIIENYDSLLKDPKWAGRLAPNVVIRFGAMPVSKPLTLLLKKVKTAAHYIVDGGNGWRDPVKRGTTVVYSDEIDFCKKLSNIIVMNPVSEWFTMWEKLNQQARQIVTASLEVEKTFDEGKTVTELAAALPDGSTLFVGNSMPIRDVDTFFQATDKKIRILANRGANGIDGVVSSATGVSAGCGKAFLLIGDLSFFHDLNGLLMTKMHKLNLCVILINNNGGGIFSFLPQADEPEKFEQLFGTPTDLAFEYAVKMYGGSYIQPQNWDQFRAALSEYKGGLQVIEVRTNRAKNVETHRKIWSQVSREMERYFQGEQQ
>CP026649.1|AVD56829.1|2413804_2414608_-|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase
MRINGLEYHVETAGDGEPLLLLHGFTGNGNTWNDTVSILRDEFRCIVVDIIGHGKTEKPDDPGRYDITKAAADLRAVLLALGIRRASVLGYSMGGRLALTFAVQYPQMVDKLVLESASPGLKTEAERLARRERDEQLAERILTGGMEAFVSHWENLPLFASQKQLPAEVQRKIRKQRLENDPSGLANSLRGMGTGAQPSWWERLSELHFPVLLAAGEWDAKFCRIAGEMEERLPHAKKIIFSHAGHAIHVEDPKKFGTMVKGFLKNC
>CP026649.1|AVD56828.1|2412945_2413764_-|1,4-dihydroxy-2-naphthoyl-CoA-synthase
MAVEWKTEHEYEDILYESYNGIAKITINRPHVRNAFRPETVTEMYDAFSRARDDANIGVIILTGMGEKAFCSGGDQKVRGNGGYVGSDNIPRLNVLDLQHLIRVIPKPVIAMVAGYAIGGGHVLHVVCDLTIAADNAIFGQTGPKVGSFDGGYGAGYLARIVGHKKAREIWYLCRQYNAQEALEMGLVNAVVPYEKLEEETIKWAEEILEKSPMAIRFLKAAFNADTDGLAGLQQFAGDATLLYYTTDEAKEGRDAFKEKRKPDFGQFPRFP
>CP026649.1|AVD56827.1|2409814_2410918_-|o-succinylbenzoate-synthase
MIGIEKVTLSVIKMPLKSPFENALEKVTEREAILLEVTDNDGVTGFGEAVAFSTPWYTEETVQTCFHMLKDVLVPLLREKPVAHPKEVSGRFQSVRRNHMAKAAIETAIWDLYAKKKQKPLWQLIGGARDHVDAGVAVGSHDTAEALRQIAAFVDEGYKRVKVKIKPGHDEAFIREIRHAFPDLALMADANSAYTLADAPRLKRLDRYGLLMIEQPLAADDIVEHAALQKQLETPVCLDESIVTYHDAESALRLGSFRVLNIKIGRVGGLYPAIQLHDLCASRGIPVWCGGMIEFGVSRAFNLALASLPGFTIPGDISSSSRFWEKDIIEPEITVENGQIRLPDRPGTGFEIDRAYVEKIRTYTETI
>CP026649.1|AVD56826.1|2409285_2409444_+|DUF1540-domain-containing-protein
MAKDVLCEVRNCVFWEEGNLCSAEEIYIVSHTGTQAENQRETDCKTFESMFS
>CP026649.1|AVD56825.1|2408332_2409223_+|adhesin
MKKLFPVLLAFTMLFVTACANKQESKQDHKISVYTTVYPLEYVTQQIGGKYVSVKTIYPPGTDEHTYEPSQKDILKLADSDFFFYIGLGLEGFANKAKQVLEGQNVKMMALGDRLPVPDKTSTKADPHVWLDPIYVKQMAGMITTQLSKKMPKQKTYFKKNYAQLAKKLDQVNAAYKQAVEKSDNKELVVSHAAYGYWVKRYGIKQIPIAGLSTSDEPSQKQLENIIQKVKQDHISYIVFEKNVPSKIAEVVQQETNTKAVYIHHLGVRTNAEIKAHKDYFTLMDDNLKALEKALQ
>CP026649.1|AVD56824.1|2408084_2408213_+|DUF4021-domain-containing-protein
MFFMEEKKEQQKKSGDFGADPDEQAINGDYGMLETEEEDKKD
>CP026649.1|AVD56823.1|2407756_2407993_+|membrane-protein-insertion-efficiency-factor-YidD
MLKFIFIKLIRFYQLAISPLFPPSCRFQPTCSNYGLEAVKRFGALRGGYLAIRRILKCHPFHAGGYDPVPDQWPVKKH
>CP026649.1|AVD56832.1|2426759_2426945_-|hypothetical-protein
MDWELLYQRACMENDIKTLKYGFSMDKISTQEKAVKTRKVCIHGHFIVCLNSVNTKQNELD
>CP026649.1|AVD56833.1|2427234_2428398_+|glycosyltransferase-family-1-protein
MKPIATPFPPVSMGDIHVYDDIIQYFNFKQVKQALPHRPKSITFVTTGIIPYDGGQTTMLHLGTELSKLGFQVYYLSYFSQPRKAMEINAEFNYAGYQGTCLDVSALKTHQSDIWIGTLWESVYVFKDKPGYKMYFVQDYEPYFYPFGDRYYLAKKTYELGLHMVSLGPWCAEMIEKECRVQSPLDVIRFPVDMEQYPFHPRNFLDYKKKKEFRIAVYTKWDSPRRAPISIQIVLNNFLKLCQKHGYQLDIVYFGTDQSAQFINGKNLGQLTKKELHELYLKSDFGIAPSMTNFSLVPYEMMSSGLPVIDFYEGTGRSFMPENCALFCHLDEQSLFQTFQNAISHPGHIAETVKNAQAHLNTVTWKETIKDFINVINAIQSKNRIVS
>CP026649.1|AVD56834.1|2428725_2429376_-|bacteriocin-ABC-transporter-ATP-binding-protein
MVICEMQNIYKSFGDKIVFENFNILINQGDFLCIAGNSGTGKSTLLNMMGLLERPDSGTINVFGKQNVKPNSHTAQKLLRHKIGFLFQNFALIDDKSVNYNLDLACVDKKRWDKNSKTQLLEKLQLDVSLNKKVYHLSGGEQQRLALARLIMKDCDFILADEPTGSLDQTNRNTVLDILSQLNHNGKTIVIVSHDPFVMERCQRVVNLNSPSKAEA
>CP026649.1|AVD56835.1|2429377_2431567_-|hypothetical-protein
MKRFLTIFSFIMFITLALSNYYSYQAESYQKLVDPSGDYTYNFEIPEDVVNANPQRLTLLKKAAKKNKVNIIRTVSYYDDKKEKTYTKAYLFLSTDTRLFDKMKIVNGRGLTIKDMMNPDRFISTDKTASKDQVGVIKNFGGKNSYSIHVLDNITANYKYSGLYKLEAASEEQYNKFIHDYVSYVNKAIGKNYFRPEMYTNITRSTKTEINNAMDTKMIAIFFVAIMILTFLFYLIARTKEISVMRLNGYTIKSISSKIFIQFFTKVFLASSLILIPWMFLIKDNNFGFVKKVYITNFIIYVILIVVLISLCFLYAKNIRIASSIKGKKPIGIIAILNGIFKVVVSIMILIMAVNLLTNLTQINQKQNSLHHWSEFHNYGVFYPVKTGNDSDVIREGKYPLDIPAYKLYSYLNQKFHAIYIDSDLYTEDSLKLNARHNIIKYIEVNPNYLNKYPILDTEGNKIVINEENEHTVILVPEQYKKKEDFNLDYFTSVREEMYKLHRDFYHQADKAKSTKIDFIYMKSGQKIFSMNPDVMPNNNNNIVDPIIQVMTEGNALVPDIHYTSSGNQTLFIKLINSDSERTYKQLLPKLQEFKLDDNLPYLVKSNEVILSEINDLHSEAKTIGYILLFMFLILTILLLQNIYLQFERNKFEFFLKKAFGHTFVEKYKKVLLLLLLTDILEFIGGIFLIDSNFFNIFIVKVLIELGLVILIIIYFERKNTVQVLKEGV
>CP026649.1|AVD56836.1|2431864_2432044_-|hypothetical-protein
MSKKNQVFLVILLILSMTGFIIIMILDPVPPWLKAYNFLMVIAWGVWIYRTGKEKGHYW
>CP026649.1|AVD56837.1|2432046_2432292_-|hypothetical-protein
MHPMIKEKNKPQESFVYKNIIPCRVLGLQPIHLQQRTAVLGMTCATLAGECKGEGSSHKEKNPRGRYQASLEFQLSWKRDD
>CP026649.1|AVD56838.1|2432344_2433250_-|EamA/RhaT-family-transporter
MNPYIALIAGVLAVTSSAILVKYSTADAGVIAFYRLFFTTIIMLPIFLAARKKAKMRMLKKDLLFSISSGALLAFHFILWFESLNLTSVASSTVLVTLQPVFAFAGSYFIFREPLSLKAIVCAAFSIFGSILISWGDFFISGKALYGDVLALISCLFVTAYMMIGQYVRKRADVVPYTFVVYLASTVVLFFYVLFAGEAFYPYSARNWICFLLLAVLPTLAGHSVFSWVVKWISASVVSVAILFEPVGAAILAYLLFGEKISWFQAVGGIIILLSIAYFLARDHAEHRRAVRLNEKSEPAR
>CP026649.1|AVD56839.1|2433340_2434030_+|MgtC/SapB-family-protein
MVFGDLEILYKLGITAVLGLIIGLERELKRKPLGLKTSLVISIISCLLTIVSIQSAYLFNHAHSVQITMDPLRLAAQIVSGIGFLGAGVILKKDNDTITGLTTAAMIWGASGIGIAVGAGFYMEAIAGVVLIIISVEIIPYLMGKAVQTKLRNKDLIIKVIVRNRDAIPCVLDAIEKQQITIENIRIKDLKDQTHLVDLKARASYKHTTVDVYRHISGMDEVAAAEVES
>CP026649.1|AVD56840.1|2434165_2435290_-|DUF1646-domain-containing-protein
MSRGGRLFCFPKKMKGSGLMVMGLTVILLLVLCLPFTKIVERNLEAFLFVMGVAACIVSRSFSWHLVQEALLHPLNITIAVLAMGLLFRWFEKPIEKGIRRISHAMPFRLFIALFVIILGLLSSVITAIVAAIILVAVIRFLRFDRKTEVRLVVLACFAIGLGAVLTPIGEPLSTIVVSKLDADFFYLLRLTGTSVIPAVIVFGVLAALIVKPGQYSSAMETAAGKEPGMATTEDGGLKAETASESYKEIVIRSFKIYLFVMALTLLGAGFEPFIEAYLLDLSPRVLYWINMVSAVLDNATLAAAEISPAMNDKAIQDILMGLLISGGMLVPGNIPNIIAAGKLKISSLEYARFAFPLGLAAMVVYFVIILFLV
>CP026649.1|AVD56841.1|2435799_2436186_-|MFS-transporter
MNRIQRIKNTYYAFNILYNMGIMVFGGTLYLYMKSIHDSYADINLFLSIFWIVGFITEIPSSVIADTFGRKKTLISSCVIRSIGLFLLFFDWGNMVFLILSAIFTLLGESLRSGTVDSWMIDSIREEE

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Crispr_ID: CP026649_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026649_11

2761380-2761471

Orphan

Consensus_repeat	Method
CAAATAATTACCTGTTTAAGAAGAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026649_11

>merge|CP026649|11|2761380-2761471|CRISPRCasFinder
CAAATAATTACCTGTTTAAGAAGAACTTACGCTAGTGGGAATGGCAATATCTGCATACTTTTGGCACAAATAATTACCTGTTTAAGAAAAAC

>CP026649|11|7|2761380-2761471|CRISPRCasFinder
CAAATAATTACCTGTTTAAGAAGAAC	TTACGCTAGTGGGAATGGCAATATCTGCATACTTTTGGCA
CAAATAATTACCTGTTTAAGAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP026649.1\|AVD57093.1\|2752707_2752974_-\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD57102.1\|2761973_2762765_-\|tryptophan-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|237285
CP026649.1\|AVD57109.1\|2769587_2770769_-\|cell-division-protein-FtsX	unknown	unknown	gnl\|CDD\|182528
CP026649.1\|AVD57103.1\|2762757_2763033_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223211
CP026649.1\|AVD57107.1\|2766642_2767242_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|235552
CP026649.1\|AVD57091.1\|2750915_2751554_-\|ABC-2-transporter-permease	unknown	unknown	gnl\|CDD\|379133
CP026649.1\|AVD57110.1\|2770765_2771449_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
CP026649.1\|AVD57097.1\|2757307_2757580_-\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD57099.1\|2760361_2761177_-\|recombination-regulator-RecX	unknown	unknown	gnl\|CDD\|237619
CP026649.1\|AVD57105.1\|2764208_2765633_-\|bifunctional-indole-3-glycerol-phosphate-synthase/phosphoribosylanthranilate-isomerase	unknown	unknown	gnl\|CDD\|236509
CP026649.1\|AVD57104.1\|2763025_2764231_-\|tryptophan-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|235288
CP026649.1\|AVD57094.1\|2753709_2753868_-\|small,-acid-soluble-spore-protein-K	unknown	unknown	gnl\|CDD\|285399
CP026649.1\|AVD57092.1\|2751531_2752407_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
CP026649.1\|AVD57095.1\|2753954_2754935_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224899
CP026649.1\|AVD57096.1\|2755113_2756232_+\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|224115
CP026649.1\|AVD57090.1\|2750572_2750881_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|290824
CP026649.1\|AVD57106.1\|2765633_2766659_-\|anthranilate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234682
CP026649.1\|AVD57098.1\|2760063_2760381_-\|DUF1811-domain-containing-protein	unknown	unknown	gnl\|CDD\|378063
CP026649.1\|AVD57101.1\|2761532_2761715_+\|YfhD-family-protein	unknown	unknown	gnl\|CDD\|372930
CP026649.1\|AVD57108.1\|2767222_2768605_-\|anthranilate-synthase-component-I	unknown	unknown	gnl\|CDD\|237431

Protein	Function_ID	Function_description	E-value
CP026649.1\|AVD57107.1\|2766642_2767242_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|235552	PRK05670, PRK05670, anthranilate synthase component II; Provisional.	7.6178e-120
CP026649.1\|AVD57109.1\|2769587_2770769_-\|cell-division-protein-FtsX	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	3.00621e-44
CP026649.1\|AVD57103.1\|2762757_2763033_-\|hypothetical-protein	gnl\|CDD\|223211	COG0133, TrpB, Tryptophan synthase beta chain [Amino acid transport and metabolism].	0.00368434
CP026649.1\|AVD57091.1\|2750915_2751554_-\|ABC-2-transporter-permease	gnl\|CDD\|379133	pfam13346, ABC2_membrane_5, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	3.8143e-14
CP026649.1\|AVD57095.1\|2753954_2754935_-\|metal-dependent-hydrolase	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	2.963e-38
CP026649.1\|AVD57110.1\|2770765_2771449_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.00169e-102
CP026649.1\|AVD57102.1\|2761973_2762765_-\|tryptophan-synthase-subunit-alpha	gnl\|CDD\|237285	PRK13111, trpA, tryptophan synthase subunit alpha; Provisional.	2.89155e-111
CP026649.1\|AVD57099.1\|2760361_2761177_-\|recombination-regulator-RecX	gnl\|CDD\|237619	PRK14135, recX, recombination regulator RecX; Provisional.	3.50701e-115
CP026649.1\|AVD57105.1\|2764208_2765633_-\|bifunctional-indole-3-glycerol-phosphate-synthase/phosphoribosylanthranilate-isomerase	gnl\|CDD\|236509	PRK09427, PRK09427, bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF.	3.77092e-134
CP026649.1\|AVD57104.1\|2763025_2764231_-\|tryptophan-synthase-subunit-beta	gnl\|CDD\|235288	PRK04346, PRK04346, tryptophan synthase subunit beta; Validated.	0
CP026649.1\|AVD57094.1\|2753709_2753868_-\|small,-acid-soluble-spore-protein-K	gnl\|CDD\|285399	pfam08176, SspK, Small acid-soluble spore protein K family. This family consists of the small acid-soluble spore proteins (SASP) belonging to the K type (sspK). The sspK are unique to the spores of Bacillus subtilis and are expressed only in the forespore compartment of sporulating cells of this organism. The sspK gene is monocistronic and transcription is primarily by the RNA polymerase with the forespore-specific sigma factor, sigma-G. Mutation deleting sspK results in loss of SspK from the spore but had no discernible effect on sporulation, spore properties or spore germination.	6.9293e-19
CP026649.1\|AVD57092.1\|2751531_2752407_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	5.19647e-69
CP026649.1\|AVD57096.1\|2755113_2756232_+\|A/G-specific-adenine-glycosylase	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	9.39498e-155
CP026649.1\|AVD57090.1\|2750572_2750881_-\|hypothetical-protein	gnl\|CDD\|290824	pfam14118, YfzA, YfzA-like protein. The YfzA-like protein family includes the B. subtilis YfzA protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 100 amino acids in length.	0.000255557
CP026649.1\|AVD57106.1\|2765633_2766659_-\|anthranilate-phosphoribosyltransferase	gnl\|CDD\|234682	PRK00188, trpD, anthranilate phosphoribosyltransferase; Provisional.	1.74848e-172
CP026649.1\|AVD57098.1\|2760063_2760381_-\|DUF1811-domain-containing-protein	gnl\|CDD\|378063	pfam08838, DUF1811, Protein of unknown function (DUF1811). This is a bacterial family of uncharacterized proteins. Some of the proteins are annotated as being transcriptional regulators. The structure of one of the proteins in this family has revealed a beta-barrel like structure with helix-turn-helix like motif.	4.50683e-59
CP026649.1\|AVD57101.1\|2761532_2761715_+\|YfhD-family-protein	gnl\|CDD\|372930	pfam14151, YfhD, YfhD-like protein. The YfhD-like protein family includes the B. subtilis YfhD protein, which is functionally uncharacterized. Its expression is regulated by the sporulation-specific sigma factor sigma-F. This family of proteins is found in bacteria. Proteins in this family are approximately 50 amino acids in length. There is a single completely conserved residue E that may be functionally important.	3.32724e-18
CP026649.1\|AVD57108.1\|2767222_2768605_-\|anthranilate-synthase-component-I	gnl\|CDD\|237431	PRK13570, PRK13570, anthranilate synthase component I; Provisional.	0

>CP026649.1|AVD57099.1|2760361_2761177_-|recombination-regulator-RecX
MPVITKISVQKNNKERYNIFLDGQYRFSVDEEVLARYQLLKGKELDELDIEAILAEDDIRKGVNTAIHFLSYRMRSEKEVRDDLIKKEFAPEVIRSVISKLYELQYLDDAEFAASFVRTQMNTTHKGPVVIRRELQQKGIAPELVKKALEIFDADQQVEHALALAEKLSRQHARLSEKLLKQKVEQGLVVKGYPPEVISAAMAALHIEKDEEAEWEALLQHAEKAKRKYGRLSGYAYRQKMKQFLYRKGFPVDLIDRYLREEEDGDGKKIQ
>CP026649.1|AVD57098.1|2760063_2760381_-|DUF1811-domain-containing-protein
MEKRYSEMSEYELKQEIAQLTEKARKAEQLGIVNEFAVLERKIAMAKSYLLDPASFQKGEIYEIEGDPGVYFKIDYIDGVFAWGYRVSGGKPIEALPISMLKQVD
>CP026649.1|AVD57097.1|2757307_2757580_-|hypothetical-protein
MPVEMSFTRVQKDKRVHDAGRNVFFIGAQKDKRVHDAGRNVFYRGLKGQKGACGRLKCLLQRFKRTKGCMWPVEMSFTEVQKDKRVHVAG
>CP026649.1|AVD57096.1|2755113_2756232_+|A/G-specific-adenine-glycosylase
MKNLPIDDFDIKSFQDDLISWFEREQRKLPWREDRDPYKIWVSEIMLQQTRVDTVIPYFRRFMEKFPTIEALADASEDEVLKAWEGLGYYSRVRNLHAAVKEVEEHYGGTVPDTPEEVSKLKGVGPYTAGAILSIAYGLPEPAVDGNVMRVLARILSIWEDIAKPSARKVFEEVVRKLISRENPSFFNQALMELGALVCTPKSPSCLLCPVREHCRAFREGTIDELPVKSKGKKQKQIRLQAAVLEDEDGRILIHKRPDKGLLANMWEFVQVEESTVLPARQVLKDYLGDVFKIEAALETEHFTEIRHVFTHLIWDIRVYHGKILNQVQETNELKCVPPDEIETFAFPVPHQKIWKAFREQAKSEKVKDIKG
>CP026649.1|AVD57095.1|2753954_2754935_-|metal-dependent-hydrolase
MDTGTHVVMGFALGGLATLDPVVAQDAVHFHSVLIATVLGSQAPDIDTLLKFKNNAVYIRNHRGITHSVPAVLLWPLAITAVLSIFFPGTDALHLWLWSFLAVFLHVFVDIFNAYGTQALRPFSYKWVALGVINTFDPFIFTIHVIGIAAWLFGAQPGPTFLAMYIFIFLYYIARFAARHDVKKAVLARIPDAENIIISPTVRFHQWKIAVRTKDAYYVASAFKSAVTILDKFKRLPVPENEIIEAAKQDKNLSAFLSFSPVYNWQVKELDNGWEVRFTDLRYRKNGHYPFVAVVKLNEDLEITGSYTGWIFNKKKLKKKLDVVPR
>CP026649.1|AVD57094.1|2753709_2753868_-|small,-acid-soluble-spore-protein-K
MRNKEKGFPYHHDNVYEGKPRAKAEYASKRADGTTNTHPQERMHASGRRGES
>CP026649.1|AVD57093.1|2752707_2752974_-|hypothetical-protein
MNLLSVLLLIIFIGLYFTNSIDYLATINLWISFILCLLLTGIPLIVSVIRFLYLKNFYVLIIGIIALLGVLFVLFMFLTPESGIPPIL
>CP026649.1|AVD57092.1|2751531_2752407_-|ABC-transporter-ATP-binding-protein
MEYALEIEGLCKSFSKSRFALKNISFSVPYGSITGFIGENGAGKTSTMGAILQTLHIDSGSIKIFGERIAEAKKEINNHIGVVYDAMNFSGNLDVIKLSKVFRYLYHNWDNQEYFNYIELFSLPKKQKINSFSRGMAMKLSIAVALSHGARLLILDEATSGLDPVGREDVLEALLKFVRDQKGAILLSSHITSDIEKVADTLVFIKKGEIVLKTSKNDLLNNYAIIQCKEHELNDLRLNGIIAYKNQTDYVDVLVSNKNELPAKFHKKNFSIDDITLLLMKGENYERTHFK
>CP026649.1|AVD57091.1|2750915_2751554_-|ABC-2-transporter-permease
MKGLILNNLYSIDKSVKFSLLISTAAIIPLIISGNPTALKIAVLLPFLIIPMNAFEVLKQDSMSGWNKFEITLPLKKSKIIQSKFITFLLLVFTSLLLTFALFYCASIFISPTVMDDFFNIGLRGMGMMFCAASLVYPLTYIFGIEKSDMITMGSIGFAFVMFFFISFLMKVFIGEMKGAEEIFSLSFLLVSIFLFILSYATSVIIYRKKEF
>CP026649.1|AVD57090.1|2750572_2750881_-|hypothetical-protein
MAKAVKNGHANAAKKRYGWYIHLLIFVLAQLVFFIFDNVSASKNIFNLNDYGKWSVSAISPIYDWLQIYKSPQFNLIFVIWGAILIIDGLIRMLPKRHSYSQ
>CP026649.1|AVD57101.1|2761532_2761715_+|YfhD-family-protein
MGRGHQHKTRDKNKATLPQVPKNMKIDGKDIEYSRELADGEDLEAQARSDAAAKRAKNSR
>CP026649.1|AVD57102.1|2761973_2762765_-|tryptophan-synthase-subunit-alpha
MGKQKLEAQFETVLARGDQAFVPYIMAGDGGMEETEKRLAFLEACGATAIELGIPFSDPVADGPVIQAAGLRAFKAGTTMKKVLDHLKAHPRQVPIILMTYFNPVFAYGLEKFAADCANAGVDGLIIPDLPIEEEEEIAGELAKCGLALIRLAAITSPKDRLEEIASRSDGFLYAVTVTGTTGTRTNFHDNIEDYLDFLSSISRVPVLAGFGVSSPEQVRRLTRYCSGVVAGSKIIELFQHGETEKIRALVESAKQQAAPNQL
>CP026649.1|AVD57103.1|2762757_2763033_-|hypothetical-protein
MGEISALESTHGTSFALQSAKTIAASLLERRDKDGGAVSRLFGIGNIPALESIHGSSFALKPAKMVAASLLERRDKDEGAVSRLFGGENNG
>CP026649.1|AVD57104.1|2763025_2764231_-|tryptophan-synthase-subunit-beta
MQTYKLPDTNGRFGTFGGRFVPETLMPAVKELEQAYHEAMNDPAFHAELEKLLKQYVGRETPLYFAENLTKLGGGPKIFLKREDLNHTGAHKINNTVGQALLTLRMGKKKVVAETGAGQHGVATATVCALLGLECMIFMGEEDIRRQKLNVFRMELLGAKVKSVAQGSGTLKDAVNEALRYWVAHVEDTHYIMGSAVGPHPFPQIVRDFQSVIGKETKKQIVEQTGKLPDAVVACVGGGSNSIGMFYPFVEDKSVKLFGVEAGGAGLGTGKHAASLSDGKLGVLHGMKTYLLQNDDGQIQEAYSVSAGLDYPGVGPEHSYLKETGRVTYTSVNDEEALDAFRLLSRTEGIIPALESAHAISFALKLAKTMGKDETIAVCLSGRGDKDVEAVSHLLGGENNG
>CP026649.1|AVD57105.1|2764208_2765633_-|bifunctional-indole-3-glycerol-phosphate-synthase/phosphoribosylanthranilate-isomerase
MAFLEKILAEKEKEVARIKAAGKAFAPNARKAPSLYETFMHAEKTSIIAEIKRASPSKGDIRTGVDPIRQALAYEKAGAGAISVLTDEAFFKGSVEDLKAVSDAVRLPVLCKDFIIDEIQIDRAKAYGASVILLIAAALSPERLRQLYDYARGAGLEVLLEVHNEAELETAVETGARIIGINNRNLKTFDVDLGVAKKLAPKISNPDVLVISESGIRTRKDVVRAEHAGAKGILVGETLMRANDPETAIKRLTGLPEKRKVKVCGIRTLEAARAAVSAGADMIGFVFAESKRKITPEKAAQIAEALPDSIEKVGVFVNESPEKMAEIAERAGLDYLQLHGDETAEDVAQIPYPVIKAFPVRTDADLEAIHDYRCDLVLLDSAGGKYRGGNGKAFDWELAKALSDERAVVLAGGLTPENVEAAILSARPHIVDVSSGVETNGEKDPDKIKTFVQAARKAFQKLEERDDNANIQTA
>CP026649.1|AVD57106.1|2765633_2766659_-|anthranilate-phosphoribosyltransferase
MKPYLEKILAQEGLTFEEMREASRALFSDEVTEGEMGAFLAVLKSKGETAEEIAGLVEVIREKAVPVPCSVPGLMDNCGTGGDGSHSFNISSTSAFVLAASGVKVAKHGNRSVSSQTGSADVLEKLGISLSFPAEEIEGLLREIGIVFLFAPNVHPALGKMMKIRKDLRIPTIFNLIGPLTNPMNLETQLLGLYRRDMLRTMAEVLGRLGRKRALVVNGAGYLDEASLSGENHFALLDGGKITTFTLTPEQVGLPYYPLEAIHGGDAQKNSDILLSVLKGEKGAYRDTVLFNAGLALFAAGRAETVKEGIQIAEQAIESGAALEKLHALIEASRKLTQEAI
>CP026649.1|AVD57107.1|2766642_2767242_-|type-1-glutamine-amidotransferase
MILLLDNYDSFTYNLYQYFCELGEEVKVFRNDRITVDEIRRLKPEAIVLSPGPGVPENAGISIETVKTFYRQIPLLGVCLGHQAIAAAFGAGITKAKEIKHGKTSLVRHDGKGIFSGLPDPVEVMRYHSLVMDRTKIPEVLEVVAESLDDGEIMAIQHQSAPCFGVQFHPESIGTETGKQMLENFLREIRKDEKVETVS
>CP026649.1|AVD57108.1|2767222_2768605_-|anthranilate-synthase-component-I
MQYKMVKLNGDVLTPIMIFKRLKGKCKFLFESSLPNDSNGRFSFIGADPVKAFIGRDDELEVIDRMTGRREIKKGKPLDLVKDLLPRLGIQLPFPFYGGAVGYIGYDAIRQYEEIGHTPEDETGIPDLHLMLYQNIAVYDHKSQTVYLVSTGEDGEAIEKNLAAMEKAIRQQTSAEPFVDYGPVDFAPAIQKQAFMKMVETAKQHIENGDIFQVVLSQRMKGTLSHDPFYFYRKLRKANPSPYMFYLDFGGYVILGASPESLIKTKGRVVYTNPIAGTRPRAKVPEEDERLENELLHDEKELAEHKMLVDLSRNDLGRVCEPGSIRVQKYMEVERFQHVMHIVSEIRGKLRDGFSGIDALISCLPAGTVSGAPKIRAMQIINSLETLKRGMYAGAVGYINLNGDIDFALAIRSLLIKDNTAYLQSGAGIVYDSDPEKEYEETLNKARSILEVQTHDFIAR
>CP026649.1|AVD57109.1|2769587_2770769_-|cell-division-protein-FtsX
MRAAELFFTAIRSLLANRRRSILTMLGIVIGIASVITIISLGKGVEKATLKNLQASNSGKQSTVVEYYADDLNAAESGFNESDLSLLNSAGASFGLAEAHIINDDNGTVDVQASLNGSEQNVTVKLLKRSSSEQEISAGHNISQNNITFADPVALISKKLAASIYIQPNRALDTAVIVNGISYHVIGVFENADDFHDIMIPKKVYKKSNISNVGNKLKLVFNRGENVSKQTKKIVSLLNKQGSHHLQGSYEHIEMGQILKGIGSVINSLTYFISAIAGISLFIAGIGVMNMMYISVSERTREIGIRLAIGATPKNILFQFLLEAVLLTGIGGLIGFGIGGGLAWLISLFLPFRAVIGVGSFLLAFCVSTFVGILFGILPAKNAANKNLIDILR
>CP026649.1|AVD57110.1|2770765_2771449_-|ABC-transporter-ATP-binding-protein
MIRLERLNKYYQQGDEKIHVLKDISLEINQGEFVAIMGPSGSGKSTLINIIGFLDNQFEGEYLFKRNSVIGKSSKDYAKLRNQNVGFVFQNFKLIANLTVAENVGLPLLYAGYRRKDIGERVNNVLQSVHLKGIAKKLPSQLSGGQQQRVAIARALISKPSFLLADEPTGALDRHTSQEILKLFLDLNQKLRSTIIMVTHDYQVASQSQRMIQIMDGRIESDRSVSK

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Crispr_ID: CP026649_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026649_12

2905353-2908949

TypeI

I-C

Consensus_repeat	Method
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CRT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	PILER-CR
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CRISPRCasFinder

54 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of CP026649_12

>merge|CP026649|12|2905353-2908949|CRT,PILER-CR,CRISPRCasFinder
GTTTGCTCATCAAGTCTTCATTAGGGAGCGACTTGATGATCCCAGGGATCGCAAATACAGCAAACGATTTCAATCCACGCCCCCATGTAGGGAGCGACGACTCGTCCGCGTTCAGTGCAAATTCGGTAACTTATTTCAATCCACGCCCCCATGTAGGGAGCGACTGTTTTTTCGGTCCAAGTTTAACCGGAATCCAATATTTCAATCCACGCCCCCATGTAGGGAGCGACGGCATAAAACGCGCCTATGTGCCGGACGGCATCATTTCAATCCACGCCCCCATGTAGGGAGCGACCCGTGTTAGCTTTCGTTGGCGAGTCAAAAAGGGGATTTCAATCCACGCCCCCATGTAGGGAGCGACCTCAGGGACCACAAGGACAACAGGGGCCTGCCGGATTTCAATCCACGCCCCCATGTAGGGAGCGACGGGATATTAACGGAAATATCGTTGATTTGGCGCTGATTTCAATCCACGCCCCCATGTAGGGAGCGACAACAGGCCTTGCGTTTGAAATACCAGCAGGATATGATTTCAATCCACGCCCCCATGTAGGGAGCGACCGTTTTTCCGGCCAACAAAAACCAAACCTTCACGATTTCAATCCACGCCCCCATGTAGGGAGCGACTTTTCAGCCGGTCATGGAGCAGACCGGAGATTTCAATTTCAATCCACGCCCCCATGTAGGGAGCGACATAAAACCGTCGCGTCCTTCAATTGTTTCACGCATTTCAATCCACGCCCCCATGTAGGGAGCGACACGATGGCATTTCCACGCTGTCGAATACACTGCTATTTCAATCCACGCCCCCATGTAGGGAGCGACTGGACAGACAATCGCAGAAATGCGGGCAAAAATCAGATTTCAATCCACGCCCCCATGTAGGGAGCGACAGCTGTCATTTGTTGATGTTGCTACGATAAATAAATTTCAATCCACGCCCCCATGTAGGGAGCGACCAAAGCTGTTCAGGCAAATCACCCGGATTTTTTATTTCAATCCACGCCCCCATGTAGGGAGCGACCCATAGCGAGCTTGTGGTATCCAGCTATGATGCAATTTCAATCCACGCCCCCATGTAGGGAGCGACTGCAGTTGCTGCATATATCGCTAAGTACGACATCATTTCAATCCACGCCCCCATGTAGGGAGCGACTTACCTTTTCATGTAGCGACCCGAAGGGCTACGGCATTTCAATCCACGCCCCCATGTAGGGAGCGACAGACGACCAGGGCAAAATATGGGCCGATACGCTCATTTCAATCCACGCCCCCATGTAGGGAGCGACGTCATACATGATATTGTGATAATTATCACCATTATTTCAATCCACGCCCCCATGTAGGGAGCGACGGCGCTGAACTACAACAAGCGTGACATCCTTGTCATTTCAATCCACGCCCCCATGTAGGGAGCGACCGCTTTGCCGCCAGAATATTCTCTTTGCTAGCTGATTTCAATCCACGCCCCCATGTAGGGAGCGACGCAAGGACGAATACCTGGCAGCAGCTGGGGACATGATTTCAATCCACGCCCCCATGTAGGGAGCGACTTTTGCGGAATTTCACCGCCTATGCGATAGTCGTTATTTCAATCCACGCCCCCATGTAGGGAGCGACTTTCATTATCCCAGTTAGGTGATTTATCTCCTCTATTTCAATCCACGCCCCCATGTAGGGAGCGACACCATGTGGTTAAAAGTTCCGGATAGGGTTGCTCGAATTTCAATCCACGCCCCCATGTAGGGAGCGACACGGCGGCCGTGAGTATCTCGTGGACGATGATGCATTTCAATCCACGCCCCCATGTAGGGAGCGACGGGGATATTTTGTGTTTGTTCTTCAACTACTGATTTCAATCCACGCCCCCATGTAGGGAGCGACCTCGCATTCGTGCATTACTTTCTTAAAATGTTCATTTCAATCCACGCCCCCATGTAGGGAGCGACATCAACGAATTATGGACGGCAACCAAGCGCGGTATTTCAATCCACGCCCCCATGTAGGGAGCGACGTCAAATCCATTAAAAATGTTCCCATGACCTGGATTTCAATCCACGCCCCCATGTAGGGAGCGACGGAGCGGCCTGGCGAGCTAAAACGATATTTTACGATTTCAATCCACGCCCCCATGTAGGGAGCGACAAGTGATTGATTTTGTGGATGAGCTGGGCGAATCATTTCAATCCACGCCCCCATGTAGGGAGCGACTTCAGCCGGTCATGGAGCAGACCGGAGATTTCAATTTCAATCCACGCCCCCATGTAGGGAGCGACTTGGCTCGATCAGCTTACAAATCAATTTAGCGCAATTTCAATCCACGCCCCCATGTAGGGAGCGACACGGCGGCCGGGAGTATTTGATAGATGATGACGCATTTCAATCCACGCCCCCATGTAGGGAGCGACCCAAGCCGTCCGATAAACAGTTCGATATACAAACATTTCAATCCACGCCCCCATGTAGGGAGCGACCCAGGGTAAAGACGAAGTGACGTCCACCCTGGATATTTCAATCCACGCCCCCATGTAGGGAGCGACGCGAATTGACCGTGGCTGATCTGGATGATCTGGATTTCAATCCACGCCCCCATGTAGGGAGCGACGTAAAATGCCAGATCGCCCGATTATATCACTTGAGATTTCAATCCACGCCCCCATGTAGGGAGCGACGCGATCGAACGGTAAGACATATGCGGTGTTGCTTATTTCAATCCACGCCCCCATGTAGGGAGCGACTTCTTAGAAATGGTGTATATATTAAATCAAAATAATTTCAATCCACGCCCCCATGTAGGGAGCGACTTACCCAAGATTTCCTGCTGCTCTTTTGCAGATTTATTTCAATCCACGCCCCCATGTAGGGAGCGACTATTGTTTGCTATTATCCGTCACATCTACTAATTATTTCAATCCACGCCCCCATGTAGGGAGCGACTTAGTCCGTATCCAGCCGTCACCTTATTCGCGACATTTCAATCCACGCCCCCATGTAGGGAGCGACACAACGCCATTTTTGCGGTTGTTCCGCTTCCCATATTTCAATCCACGCCCCCATGTAGGGAGCGACTAGAGTCCGCGCTTAGCACGGCATCAACAGCGGCGATTTCAATCCACGCCCCCATGTAGGGAGCGACTAAATCGTTACCAAGATCATTGATACTATCACGATTTCAATCCACGCCCCCATGTAGGGAGCGACGTTGATTTAGCTGCAGTATCCAGACTTAAGCCGATTTCAATCCACGCCCCCATGTAGGGAGCGACGTCAACTTGCCGATGCAATTGGCGTTAGTCCAGGTATTTCAATCCACGCCCCCATGTAGGGAGCGACTTCTACAGAAGAAGTTGTCCTCGTAGCTTCTCCAATTTCAATCCACGCCCCCATGTAGGGAGCGACTTGTGCTTTTAGTGATTCGTTTTCATCACGAACAATTTCAATCCACGCCCCCATGTAGGGAGCGACACAGCACCTGTAATTTCATTTAAAGCTTCTTCTGATTTCAATCCACGCCCCCATGTAGGGAGCGACTTGGTATTCGCCGTAACCTTTAGGGTCGCTACATATTTCAATCCACGCCCCCATGTAGGGAGCGAC

>CP026649|12|5|2905353-2908949|CRT
GTTTGCTCATCAAGTCTTCATTAGGGAGCGAC	TTGATGATCCCAGGGATCGCAAATACAGCAAACG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GACTCGTCCGCGTTCAGTGCAAATTCGGTAACTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TGTTTTTTCGGTCCAAGTTTAACCGGAATCCAAT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGCATAAAACGCGCCTATGTGCCGGACGGCATC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CCGTGTTAGCTTTCGTTGGCGAGTCAAAAAGGGG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CTCAGGGACCACAAGGACAACAGGGGCCTGCCGG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGGATATTAACGGAAATATCGTTGATTTGGCGCTG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	AACAGGCCTTGCGTTTGAAATACCAGCAGGATATG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CGTTTTTCCGGCCAACAAAAACCAAACCTTCACG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTTTCAGCCGGTCATGGAGCAGACCGGAGATTTCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ATAAAACCGTCGCGTCCTTCAATTGTTTCACGC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACGATGGCATTTCCACGCTGTCGAATACACTGCT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TGGACAGACAATCGCAGAAATGCGGGCAAAAATCAG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	AGCTGTCATTTGTTGATGTTGCTACGATAAATAA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CAAAGCTGTTCAGGCAAATCACCCGGATTTTTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CCATAGCGAGCTTGTGGTATCCAGCTATGATGCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TGCAGTTGCTGCATATATCGCTAAGTACGACATC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTACCTTTTCATGTAGCGACCCGAAGGGCTACGGC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	AGACGACCAGGGCAAAATATGGGCCGATACGCTC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTCATACATGATATTGTGATAATTATCACCATT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGCGCTGAACTACAACAAGCGTGACATCCTTGTC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CGCTTTGCCGCCAGAATATTCTCTTTGCTAGCTG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GCAAGGACGAATACCTGGCAGCAGCTGGGGACATG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTTTGCGGAATTTCACCGCCTATGCGATAGTCGTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTTCATTATCCCAGTTAGGTGATTTATCTCCTCT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACCATGTGGTTAAAAGTTCCGGATAGGGTTGCTCGA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACGGCGGCCGTGAGTATCTCGTGGACGATGATGC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGGGATATTTTGTGTTTGTTCTTCAACTACTG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CTCGCATTCGTGCATTACTTTCTTAAAATGTTC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ATCAACGAATTATGGACGGCAACCAAGCGCGGT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTCAAATCCATTAAAAATGTTCCCATGACCTGG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGAGCGGCCTGGCGAGCTAAAACGATATTTTACG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	AAGTGATTGATTTTGTGGATGAGCTGGGCGAATC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTCAGCCGGTCATGGAGCAGACCGGAGATTTCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTGGCTCGATCAGCTTACAAATCAATTTAGCGCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACGGCGGCCGGGAGTATTTGATAGATGATGACGC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CCAAGCCGTCCGATAAACAGTTCGATATACAAAC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CCAGGGTAAAGACGAAGTGACGTCCACCCTGGAT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GCGAATTGACCGTGGCTGATCTGGATGATCTGG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTAAAATGCCAGATCGCCCGATTATATCACTTGAG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GCGATCGAACGGTAAGACATATGCGGTGTTGCTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTCTTAGAAATGGTGTATATATTAAATCAAAATA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTACCCAAGATTTCCTGCTGCTCTTTTGCAGATTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TATTGTTTGCTATTATCCGTCACATCTACTAATT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTAGTCCGTATCCAGCCGTCACCTTATTCGCGAC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACAACGCCATTTTTGCGGTTGTTCCGCTTCCCAT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TAGAGTCCGCGCTTAGCACGGCATCAACAGCGGCG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TAAATCGTTACCAAGATCATTGATACTATCACG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTTGATTTAGCTGCAGTATCCAGACTTAAGCCG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTCAACTTGCCGATGCAATTGGCGTTAGTCCAGGT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTCTACAGAAGAAGTTGTCCTCGTAGCTTCTCCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTGTGCTTTTAGTGATTCGTTTTCATCACGAACA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACAGCACCTGTAATTTCATTTAAAGCTTCTTCTG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTGGTATTCGCCGTAACCTTTAGGGTCGCTACAT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC

>CP026649|12|2|2905419-2908949|PILER-CR
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GACTCGTCCGCGTTCAGTGCAAATTCGGTAACTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TGTTTTTTCGGTCCAAGTTTAACCGGAATCCAAT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGCATAAAACGCGCCTATGTGCCGGACGGCATC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CCGTGTTAGCTTTCGTTGGCGAGTCAAAAAGGGG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CTCAGGGACCACAAGGACAACAGGGGCCTGCCGG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGGATATTAACGGAAATATCGTTGATTTGGCGCTG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	AACAGGCCTTGCGTTTGAAATACCAGCAGGATATG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CGTTTTTCCGGCCAACAAAAACCAAACCTTCACG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTTTCAGCCGGTCATGGAGCAGACCGGAGATTTCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ATAAAACCGTCGCGTCCTTCAATTGTTTCACGC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACGATGGCATTTCCACGCTGTCGAATACACTGCT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TGGACAGACAATCGCAGAAATGCGGGCAAAAATCAG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	AGCTGTCATTTGTTGATGTTGCTACGATAAATAA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CAAAGCTGTTCAGGCAAATCACCCGGATTTTTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CCATAGCGAGCTTGTGGTATCCAGCTATGATGCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TGCAGTTGCTGCATATATCGCTAAGTACGACATC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTACCTTTTCATGTAGCGACCCGAAGGGCTACGGC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	AGACGACCAGGGCAAAATATGGGCCGATACGCTC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTCATACATGATATTGTGATAATTATCACCATT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGCGCTGAACTACAACAAGCGTGACATCCTTGTC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CGCTTTGCCGCCAGAATATTCTCTTTGCTAGCTG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GCAAGGACGAATACCTGGCAGCAGCTGGGGACATG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTTTGCGGAATTTCACCGCCTATGCGATAGTCGTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTTCATTATCCCAGTTAGGTGATTTATCTCCTCT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACCATGTGGTTAAAAGTTCCGGATAGGGTTGCTCGA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACGGCGGCCGTGAGTATCTCGTGGACGATGATGC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGGGATATTTTGTGTTTGTTCTTCAACTACTG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CTCGCATTCGTGCATTACTTTCTTAAAATGTTC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ATCAACGAATTATGGACGGCAACCAAGCGCGGT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTCAAATCCATTAAAAATGTTCCCATGACCTGG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGAGCGGCCTGGCGAGCTAAAACGATATTTTACG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	AAGTGATTGATTTTGTGGATGAGCTGGGCGAATC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTCAGCCGGTCATGGAGCAGACCGGAGATTTCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTGGCTCGATCAGCTTACAAATCAATTTAGCGCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACGGCGGCCGGGAGTATTTGATAGATGATGACGC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CCAAGCCGTCCGATAAACAGTTCGATATACAAAC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CCAGGGTAAAGACGAAGTGACGTCCACCCTGGAT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GCGAATTGACCGTGGCTGATCTGGATGATCTGG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTAAAATGCCAGATCGCCCGATTATATCACTTGAG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GCGATCGAACGGTAAGACATATGCGGTGTTGCTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTCTTAGAAATGGTGTATATATTAAATCAAAATA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTACCCAAGATTTCCTGCTGCTCTTTTGCAGATTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TATTGTTTGCTATTATCCGTCACATCTACTAATT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTAGTCCGTATCCAGCCGTCACCTTATTCGCGAC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACAACGCCATTTTTGCGGTTGTTCCGCTTCCCAT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TAGAGTCCGCGCTTAGCACGGCATCAACAGCGGCG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TAAATCGTTACCAAGATCATTGATACTATCACG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTTGATTTAGCTGCAGTATCCAGACTTAAGCCG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTCAACTTGCCGATGCAATTGGCGTTAGTCCAGGT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTCTACAGAAGAAGTTGTCCTCGTAGCTTCTCCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTGTGCTTTTAGTGATTCGTTTTCATCACGAACA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACAGCACCTGTAATTTCATTTAAAGCTTCTTCTG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTGGTATTCGCCGTAACCTTTAGGGTCGCTACAT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC

>CP026649|12|8|2905419-2908949|CRISPRCasFinder
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GACTCGTCCGCGTTCAGTGCAAATTCGGTAACTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TGTTTTTTCGGTCCAAGTTTAACCGGAATCCAAT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGCATAAAACGCGCCTATGTGCCGGACGGCATC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CCGTGTTAGCTTTCGTTGGCGAGTCAAAAAGGGG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CTCAGGGACCACAAGGACAACAGGGGCCTGCCGG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGGATATTAACGGAAATATCGTTGATTTGGCGCTG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	AACAGGCCTTGCGTTTGAAATACCAGCAGGATATG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CGTTTTTCCGGCCAACAAAAACCAAACCTTCACG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTTTCAGCCGGTCATGGAGCAGACCGGAGATTTCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ATAAAACCGTCGCGTCCTTCAATTGTTTCACGC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACGATGGCATTTCCACGCTGTCGAATACACTGCT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TGGACAGACAATCGCAGAAATGCGGGCAAAAATCAG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	AGCTGTCATTTGTTGATGTTGCTACGATAAATAA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CAAAGCTGTTCAGGCAAATCACCCGGATTTTTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CCATAGCGAGCTTGTGGTATCCAGCTATGATGCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TGCAGTTGCTGCATATATCGCTAAGTACGACATC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTACCTTTTCATGTAGCGACCCGAAGGGCTACGGC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	AGACGACCAGGGCAAAATATGGGCCGATACGCTC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTCATACATGATATTGTGATAATTATCACCATT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGCGCTGAACTACAACAAGCGTGACATCCTTGTC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CGCTTTGCCGCCAGAATATTCTCTTTGCTAGCTG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GCAAGGACGAATACCTGGCAGCAGCTGGGGACATG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTTTGCGGAATTTCACCGCCTATGCGATAGTCGTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTTCATTATCCCAGTTAGGTGATTTATCTCCTCT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACCATGTGGTTAAAAGTTCCGGATAGGGTTGCTCGA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACGGCGGCCGTGAGTATCTCGTGGACGATGATGC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGGGATATTTTGTGTTTGTTCTTCAACTACTG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CTCGCATTCGTGCATTACTTTCTTAAAATGTTC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ATCAACGAATTATGGACGGCAACCAAGCGCGGT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTCAAATCCATTAAAAATGTTCCCATGACCTGG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GGAGCGGCCTGGCGAGCTAAAACGATATTTTACG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	AAGTGATTGATTTTGTGGATGAGCTGGGCGAATC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTCAGCCGGTCATGGAGCAGACCGGAGATTTCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTGGCTCGATCAGCTTACAAATCAATTTAGCGCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACGGCGGCCGGGAGTATTTGATAGATGATGACGC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CCAAGCCGTCCGATAAACAGTTCGATATACAAAC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	CCAGGGTAAAGACGAAGTGACGTCCACCCTGGAT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GCGAATTGACCGTGGCTGATCTGGATGATCTGG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTAAAATGCCAGATCGCCCGATTATATCACTTGAG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GCGATCGAACGGTAAGACATATGCGGTGTTGCTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTCTTAGAAATGGTGTATATATTAAATCAAAATA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTACCCAAGATTTCCTGCTGCTCTTTTGCAGATTT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TATTGTTTGCTATTATCCGTCACATCTACTAATT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTAGTCCGTATCCAGCCGTCACCTTATTCGCGAC
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACAACGCCATTTTTGCGGTTGTTCCGCTTCCCAT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TAGAGTCCGCGCTTAGCACGGCATCAACAGCGGCG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TAAATCGTTACCAAGATCATTGATACTATCACG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTTGATTTAGCTGCAGTATCCAGACTTAAGCCG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	GTCAACTTGCCGATGCAATTGGCGTTAGTCCAGGT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTCTACAGAAGAAGTTGTCCTCGTAGCTTCTCCA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTGTGCTTTTAGTGATTCGTTTTCATCACGAACA
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	ACAGCACCTGTAATTTCATTTAAAGCTTCTTCTG
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC	TTGGTATTCGCCGTAACCTTTAGGGTCGCTACAT
ATTTCAATCCACGCCCCCATGTAGGGAGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
CP026649.1\|AVD57208.1\|2890194_2890884_-\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|119407
CP026649.1\|AVD57220.1\|2911092_2911953_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|187820
CP026649.1\|AVD57213.1\|2899860_2901006_-\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|236506
CP026649.1\|AVD57217.1\|2909117_2909408_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
CP026649.1\|AVD57214.1\|2901382_2902684_-\|glutamate:protein-symporter	unknown	unknown	gnl\|CDD\|183075
CP026649.1\|AVD57222.1\|2913857_2914577_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
CP026649.1\|AVD57219.1\|2910446_2911103_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
CP026649.1\|AVD57211.1\|2895134_2895557_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224531
CP026649.1\|AVD57225.1\|2917671_2920911_-\|helicase-SNF2	unknown	unknown	gnl\|CDD\|377999
CP026649.1\|AVD57218.1\|2909418_2910450_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
CP026649.1\|AVD57210.1\|2894501_2895110_+\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD57223.1\|2914774_2917201_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
CP026649.1\|AVD57887.1\|2898147_2899062_-\|DUF1002-domain-containing-protein	unknown	unknown	gnl\|CDD\|377628
CP026649.1\|AVD57209.1\|2892438_2893974_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225107
CP026649.1\|AVD57224.1\|2917335_2917527_-\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD57216.1\|2904735_2905155_+\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP026649.1\|AVD57226.1\|2921288_2922704_-\|ISLre2-family-transposase	unknown	unknown	gnl\|CDD\|284250
CP026649.1\|AVD57215.1\|2903343_2903967_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366010
CP026649.1\|AVD57221.1\|2911976_2913857_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
CP026649.1\|AVD57212.1\|2896308_2897622_+\|IS1380-like-element-ISBco1-family-transposase	unknown	unknown	gnl\|CDD\|379340

Protein	Function_ID	Function_description	E-value
CP026649.1\|AVD57208.1\|2890194_2890884_-\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	5.08453e-67
CP026649.1\|AVD57220.1\|2911092_2911953_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	2.89273e-134
CP026649.1\|AVD57213.1\|2899860_2901006_-\|metallophosphoesterase	gnl\|CDD\|236506	PRK09420, cpdB, bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase.	5.10782e-155
CP026649.1\|AVD57217.1\|2909117_2909408_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.60661e-36
CP026649.1\|AVD57214.1\|2901382_2902684_-\|glutamate:protein-symporter	gnl\|CDD\|183075	PRK11283, gltP, glutamate/aspartate:proton symporter; Provisional.	0
CP026649.1\|AVD57222.1\|2913857_2914577_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	6.65501e-99
CP026649.1\|AVD57219.1\|2910446_2911103_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	4.39067e-31
CP026649.1\|AVD57211.1\|2895134_2895557_+\|hypothetical-protein	gnl\|CDD\|224531	COG1615, COG1615, Uncharacterized conserved protein [Function unknown].	0.00321078
CP026649.1\|AVD57225.1\|2917671_2920911_-\|helicase-SNF2	gnl\|CDD\|377999	pfam08455, SNF2_assoc, Bacterial SNF2 helicase associated. This domain is found in bacterial proteins of the SWF/SNF/SWI helicase family to the N-terminus of the SNF2 family N-terminal domain (pfam00176) and together with the Helicase conserved C-terminal domain (pfam00271). The function of the domain is not clear.	2.38933e-102
CP026649.1\|AVD57218.1\|2909418_2910450_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
CP026649.1\|AVD57887.1\|2898147_2899062_-\|DUF1002-domain-containing-protein	gnl\|CDD\|377628	pfam06207, DUF1002, Protein of unknown function (DUF1002). This protein family has no known function. Its members are about 300 amino acids in length. It has so far been detected in Firmicute bacteria and some archaebacteria.	2.16753e-81
CP026649.1\|AVD57223.1\|2914774_2917201_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.27482e-82
CP026649.1\|AVD57209.1\|2892438_2893974_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.12044e-19
CP026649.1\|AVD57216.1\|2904735_2905155_+\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	9.77728e-16
CP026649.1\|AVD57226.1\|2921288_2922704_-\|ISLre2-family-transposase	gnl\|CDD\|284250	pfam06782, UPF0236, Uncharacterized protein family (UPF0236).	1.51899e-46
CP026649.1\|AVD57215.1\|2903343_2903967_+\|histidine-phosphatase-family-protein	gnl\|CDD\|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	3.01398e-69
CP026649.1\|AVD57221.1\|2911976_2913857_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	5.54126e-178
CP026649.1\|AVD57212.1\|2896308_2897622_+\|IS1380-like-element-ISBco1-family-transposase	gnl\|CDD\|379340	pfam13701, DDE_Tnp_1_4, Transposase DDE domain group 1. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	0

>CP026649.1|AVD57216.1|2904735_2905155_+|XRE-family-transcriptional-regulator
MADHGNENMENVKEIFAARLKKVRTAQGYSQPELAKKVGVSDRNISNYETGYSFPSIKVLYRISQVLKVSIDYLLGLTNHAGLKTNEAVSNPEKKLLETLSHEPDLYQMMLKDPEKMANRIYQTWNFIRELDNEDDRNT
>CP026649.1|AVD57215.1|2903343_2903967_+|histidine-phosphatase-family-protein
MTLFYFVRHGQTEWNADRNRYCGRSDIGLSQTGVRQAELAAGFLKDIPFNAVYASTLGRAARTAEILVEGRNLKIYQDPRLVETDFGAWEGERQEDFSVKYADNWEAWLKDPGATHAGYTGETAVQVYQRVRACIDELVEKHPEETVLVVAHSMAIRFFVAGTLEVPFKNYRMIPQDNTGITIYKETPENAGFLAINLNTHLSSIKS
>CP026649.1|AVD57214.1|2901382_2902684_-|glutamate:protein-symporter
MKRVSLAWQIFIGLILGIAIGGIFHGNDTVAHILQPFGDFFLRLIKMIVIPIVVSSLIVGVAGAGDMKQVGKLGLKALIYFEIVTTIAIVVGLLAGNLFHPGTGVDMGSLAKTSISSYVETTKETQHNGIVDTILSIVPTNLFESLSQGNMLPIIFFSVMFGIGVAAIGEKGKPVLRFCQGVSEAMFYVTNLVMKVAPIGVFGLIGVTVTQFGLKSLIPLSKLVFTVYGTIIFFVVVVLGLIAWLFRVNIFNLFKILKDELILAYSTASSEAVLPRLMEKMEKFGCPKSITTLVIPTGYSFNLDGSTLYQSLAALFIAQMYGIHMSIGAQISLVLVLMVTSKGIAGVPGVSFVVLLATLGTVGIPLEGLAFIAGIDRILDMARTACNVVGNTLATIIVSKWEGKYDKEKAEAYLAEISGGGHDSKDHKYVTES
>CP026649.1|AVD57213.1|2899860_2901006_-|metallophosphoesterase
MGKKMLLWAAVLSLALFPRTEHADAAFWFQSKRATVDLRLLETSDLHGYMLNYDYAARTEAETYGLALTASLIAAERKAAKNTMLFDDGDLLEGNEMAAYVARRPLKKGEIHPFIRVMNHLNYDAATVGNHDFHYGLDFLKQTINGAKFPFVNANIYYNFEKNDTDDQNFFKPYVILDKKVEDRSGHHHHLKIGVIGFVTPSVIEWEKPSLGGKVKAKDILHTAAWFVPRMKAEGADLIIALAHCGVDPAAKQPFYTGDAVYLLSEVKGIDAILFGHQHRVFPSEFFAGVPGVDIRKGTINGVPAVMPGKWGSHLGVISLTLEKKGEKWEMTQAQSEAKPVYAIHNQQAKSIVRPDPDIVRMTAELQKNVLGSKFTLYSRN
>CP026649.1|AVD57887.1|2898147_2899062_-|DUF1002-domain-containing-protein
MLKRLGWSWFIAMIALGFTMNGVAKASGDNSTVIDEKYGKPIVATGAALSASQKAEVEKELGVDDANNVEEITVTGDDLVHYIPDGNRNSNMYSSAKITRTDSGGIQVNIVTPENITEVTADMYKNALLTAGIKNAEVEVASPLKVTGHSALVGIYKAYDNSDKSGDKLNSDRTEVASQELSVATDLAKKEGLSNDQVTQLLTEIKQEIANQHPATKEDIEKIVDDKLKDLNINLSDSDRKLLYDLFDQMRKLNINFGSVKSELSSLSDKLSDKINKAAGDKGFWQSVKDFFQNIFDAIRGLFQ
>CP026649.1|AVD57212.1|2896308_2897622_+|IS1380-like-element-ISBco1-family-transposase
MVTLTQKTLDFNHKIKMSNDGGSLSSDTGEFLFREFDEKIGFSKTLVKYLRLNDSRKYYLHSNENLLRQKVYQLIAGYAEDDAADQLTHDPVFKEIIETPTLASQPSLSRFYTRFDKDSIEQLNLANQEMLDKIHCFRQSKELFIDLDSTHSDTYGDQESSSYNTHYGTMGFHPLVAFDGATGDFLKAQLRPGNVYTSNGVVEFIRPLIKHYNEMFPETTLFLRGDSGFAVPGLYDLCEEESVLYIIRLKSNSQLQSLAKEYHPSSAPLDVSKTETYYEETIYQAKSWSKPRRVIIQSVRPAGELFFTHSFFVTNFELAFPQDIVRAYQKRGTMENYIKEAKNGFYFDHMNSHAFLVNEVKMMLTLLAYNLTNWLRTLCFPEGQKTMQIDTIRTRLIKAASKVVKSGRSLYFKLSSSFVYQNFFWDVLNRIQKLQLE
>CP026649.1|AVD57211.1|2895134_2895557_+|hypothetical-protein
MGKFHMFRMKFRNWRRSRPFWGATFTLLSGMIILYVPVQLLEIAAAPGSMVSIGLIFGGLIFLIGRMGYFFPKFNMVFGILAIFLSVLSIMGAMGGFFIGTLLGIIGGSLSVSWRVIRQEEVPAGVGPMEEIAAGSAEER
>CP026649.1|AVD57210.1|2894501_2895110_+|hypothetical-protein
MNEGALVLQGQGRTSKKWFFTALLSGHIFLGGLLAVLGINGVAVAATVGGIGKFNVSFKQMQGTGFKLYGSLYGDPSKGEDHVKPVFVNEIDKVTIQDLVISKDVKIPVLGDYQVKITAGDGNTPVHLNGLIQKAALVQGDAVFTNMNISENYVTSDDPQAASKAFTQGADTLTIKNGSLDTHYLFQKVANLPNLKVQFVKK
>CP026649.1|AVD57209.1|2892438_2893974_-|helix-turn-helix-transcriptional-regulator
MSLSLNAHMDMVMKHGVDLLRSHQQQIIAECTGILQYLRETHKGSADDFEFAFNCFVAFFRSGQQSVETLIDDIRLQWVKEFHRPPEPHVLIFILTLIENSVHKAIKESTTRSFHLHPSVQYLFSKICEEMLLISKQETFQMDSFCEQLTKSEQLRIEWIARVSHVDGGYRLKKVIGMEENAIDSGLFERTDPSWFWLSEALLKRTPRRKPDERRNVFPVPWKNETLIFCMSDQDVSATIPFLTYAMHLLQMEEERNGKVYAGDQWKDAVILFNEWIMRSQDLNEAIQNIAFGYAQYLPFERCALFRYSQSDAAGFGLFGYHFNNTAIRNIKETIDRFPSISKILLGKGQQVNMVQHFQPLYIPKASEEFPMQYVKEFELESVVVAPIYVPSEGVLIGGAILDQGPGKFFEVDSSTFTALLKFGQSAGELLAKFLKANQWDEKQPELVQLSAREIHILQLLADGASTTEAAEMLHLSEYTVRDYVSSLMKRLHARNRTEAAVKAMRLGLIH
>CP026649.1|AVD57208.1|2890194_2890884_-|LysM-peptidoglycan-binding-domain-containing-protein
MFKLFLDPGHGGKDPGAEGNGLEEKDITLEIAKQIQDILTNHYQNVSVKMSRTTDKFVSLEERTDAANSWGATFFLSIHINSGNGTGFESYIYPKSGSATATYQKTIHQEVVKLNDLKDRGRKTADFHVLRESIMPALLTENGFIDTASDAKKMKKNSWIEEVAQGHVNGLAKAFELKKKSGATYHKVVKGDTVYALSKEYGSTIKEIKKWNNLDDDYTIRVGERLRVK
>CP026649.1|AVD57217.1|2909117_2909408_-|CRISPR-associated-endonuclease-Cas2
MLVVITYDVSTLTGAGQKRLRKVAKVCQNYGQRVQNSVFECFVDATQFASLKIELSNIIDPDEDSLRFYQLGNNYKNKVMHIGAKPSLDLEDPLIF
>CP026649.1|AVD57218.1|2909418_2910450_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFITQPEVYLSLDGDNIVLLKEKEQLGRLPLHNLESVVAFGYTGASPALMGYCAERNISLIFFTMNGRFLARVIGKSRGNVVLRKKQYRISDDEIASVQIARNFIIGKIYNQKWILERMTRDYPLRIDVTQFKDVSRFLSAIIKQVRLCDSLETLRGLEGQAAINYNKLFDQMILQQKDDFFFHHRSRRPPLDNVNAMLSFAYTLLANDTASALEGVGLDAYVGFMHQDRPGRVSLALDLMEELRGVYADRFVLSLINTKVINKDDFLKKENGTVIMTDEARKKFLKAWQNKKQEKITHPFLGEKISWGLVPHAQALLLARFLRGDLDEYPPFLWK
>CP026649.1|AVD57219.1|2910446_2911103_-|CRISPR-associated-protein-Cas4
MAFDEDEYLMLSGIQHFQFCKRQWALIHIEQAWEENVRTVEGQNIHQKTDSPFIREKRGSKLIVRAMPIKSNELKLTGICDVVEFVKDKNGVEIYGNEGKYIPYPVEYKRGKPKKNDSDILQLVAQAMCLEEMLLCEVNKGYIFYNEIKRRIEIPITLDEKNKVRKIAAEMQDYYQRRYTPKVKTGPFCNQCSLQNICLPNIIRKRAVSSYIEGKINE
>CP026649.1|AVD57220.1|2911092_2911953_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSALDHKIDFAVVLSVTKANPNGDPLNGNRPRQNYDGYGEISDVAIKRKIRNRLQDMGESIFVQSNDRKNDSYNSLKERADANPELNKIFKSKDGSGETFAAIACQEWIDVRSFGQVFAFKGSGNKGVSVGVRGPVSIHTATSVSPIDITSMQITKSVNSEPGKDRGSDTMGMKHRVDFGVYVLYGSINPQLAEKTGFSNEDAEKIKQALVTLFENDASSARPEGSMEVKKVYWWEHQSKLGQYSSAKVHRSLAVTPLVDNPKTFEDYEITLNELSGLKVDVIDGI
>CP026649.1|AVD57221.1|2911976_2913857_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLLNLYETYQANEEQVGKIEKKRNDQEYTLLPVSHTTQTAHLEVQVTEDGNFYYAEVINDKKDAVTLIPCTEESSSRAGKKIAPYPLHDKLIYVAGDFVAYGGKIEEPFSYYIQQLGEWANSPFSNAKVQSIYAYLKKKQLIHDLVEAGILFLDNNGQLIDKWDSKYGDKPPLYSTVTGSVESAFVRFTVYSPEKILTKVWKDPEMYESFIKFYNQHLSDRDLCYVTGEFLPSTERHANKIRNSGDKAKLISANDSSGFTYRGRFTESKQVASISYKASQKAHNALKWLINKQGKIIDNRVFLVWENGGNEVPSVTEDSYDITSLDPFANGNNPKIAFTNQEFAREFSKAMDGYKSNLSTEASINILVLDSATTGRMAVLYYRNLNKEIYFENLVKWHTTCAWLHRYRKNEDNQPILFFGAPATKDIAFAAYGPNASDKVVKGLMERMLPCIVEGRRIPTDIVRSALRRASNPVALEKWEWEKILSIACALINKEEGYNLALDKENNNRDYLFGRLLAIADVFERNALDSGENRATNAIRYMNAFSQHPARTWGTIQASLQPYQVRLGKKGTYYAMLIDEVASKLKYEDFNDRPLSGKFLLGFYSQRYDLYQKKETNTVGQTKE
>CP026649.1|AVD57222.1|2913857_2914577_-|type-I-C-CRISPR-associated-protein-Cas5
MRNSIEFEVYGKYALFTDPLTKMGGEKLSYQIPTYQALKGIVESIYWKPTILMIIDDLRVMNPIKMESKGVRPIEYNGGNTLANYTYLRDVRYKVRAHFIFNPHRPDLAFDRNEHKHHNILKRSLKAGGRRDIFLGARECQGYVEPCVFEEGEGYYDQTEEVYFGTMVHGINYPDETGRNEMEVRLWNPVMKNGVIHFIRPDECKLVRRVAEMEMKAFTKDNVESADVLLKELERGGEL
>CP026649.1|AVD57223.1|2914774_2917201_-|CRISPR-associated-helicase/endonuclease-Cas3
MEYIAHIRESDKKVQTVEEHLLAAKELAETYGEKIGVKHITGLAALLHDLGKYTSAFRNYVLEAVNNPDHPPKRGSVDHSTAGGKLLFKMFHSGKASPHKALLAEIVGNAIISHHSYLQDFISPEMDLKYLNRVDSKEIDEFETAKENFFEKVMSPTRFSSYVNQAEIELKNFIMKDASKTLTHKMMFLTKYIFSALIDADRTNTRLFEENKPEKEQFSVSKLFNQYYEKLLLTLDSYKENSSANARINRLRSEMSEQCDAFAEKPSGIYTLSIPTGGGKTFASLRYALKHAQLYNKKRIIYIVPFTTIIEQNAEEVRKVLQDDVNILEHHSNVVEDADENDEQQDGIMSVQQRLKLAKDNWDVPIIFTTMVQFLNVFYAKGSRNIRRLHNMSEAVLIFDEVQKVPVPCISLFNEALNFLKTYCHSSILLCTATQPALNYVEHQLQVSPNPEIIRGLDNVIDAFKRVEIVDRATDETFNTEKLANFIEKRMTEVSSVLVILNTKGVVKKLYEHLNSNDNNINIFHLSTSMCAAHRNQILEEVRHCLDAGKKVICVSTQLIEAGVDVSFECVIRSLAGLDSIAQAAGRCNRHGEKETGFVYVINHEEENLSRLPEIKKGKETSKRIFIDLKNTPSIYNGNVLSIQAMEKYFKEFYTAFDANLDYNVPSLQKNMVEMLTTDPNNYSYVRAYCSNTKKKYPLFLSSSFYTAAEKFRVIDDKTTSVIVPFGKGNDVIAELSSNATIEDLSKLMKKAQQYTINLYSQELGKLERNGGIISLFDGKILALKEGAYDHEFGLNVENDSELDFLSI
>CP026649.1|AVD57224.1|2917335_2917527_-|hypothetical-protein
MLQVSRLREAFADALNKVFAAFSKDASGLPIARLSLPREMAGCIKENLRIPGWSFPSLVATDM
>CP026649.1|AVD57225.1|2917671_2920911_-|helicase-SNF2
MVDYLLFEEDVEMMYSPAIFHRGMSYYMQGRVKKLIFNKDSTWTAIVKGSKTYYVTIYYDEEFGEFSNVCTCPAHEQYGECKHEVAAMLAIANGEEEAAEPNIGDVSETHQHMKTLQLMNIFSGLQQSMMETKHNAARKPLRLEYFLKATNVSGFGSDHFLTIEIKIGPGRTYVVRDIKDFLGNVSRGNPHAFTKNFIYDPDEHAFEEEDKEIVEMLLYMLSTQQLYEASMDRWYRFALERELVIPPFIARPLIKKLANRKCKFKYERYAADSIVLHQEEELPLSFRLDGNSQGGPGFLLQLKSLRDLLLFEQYGLAFYKGGFYELSTDQLALLTALEDFYKKSGDEVEIQQEQMSPFLSNVLPGLKRIGKVKLTKDIKGKIVQPKLQTKIFMDNEDEKITLRIEHHYGSRVIDPFMDEETPDDDKILLRDVEKEQKIMTMIEQSPLKYNGKQLYLENDEEALYEFIFTILPQLEEEAEVYIAGAIKSYFQTSHYTPLTSVDMDTSGNFLEVNFDMDGIDEEEIRNVLRSVIEKKRYYRLPDGAFVSLESDEFEHIGQLLGELHVSKKELEDTRLKVPVYRGLQVEELMKTRDKYAVKFGKAFRKLVQQLKNPEDTDFELPKGLEAKMRDYQVTGFQWFKSLAFYRLGGILADDMGLGKTLQSISYMLSEKEANPDIKPFLVVAPASLIYNWKSEIKKFAPGLSSMVIAGTPSERKAFFKAGELPDVLITSYPTLRQDIEEYEKIEFDTLILDEAQAIKNYATKTAAAVRNVQAGRRFALSGTPIENSIDELWSIFQAVLPGFFPPLPEFRKMEQEKISRMVRPFILRRVKKDVLKELPDKIETNHLSELTKPQKELYLAYLDRIRHETAQTLAEGDFNRNRIKILAGLTRLRQLCCHPSLFVENYRGDSGKLEQLVELAHTAIENGKRLLIFSQFSSMLQMIRTRLSDEGIDSFYLDGQTPSRERVEMADRFNSGEKNVFLISLKAGGTGLNLTGADTVVLYDLWWNPAVEEQAAGRAHRIGQKNVVQVIRLIARGTIEEKIYELQQKKKELIEQVIQPGETMLNSLNEEEIKELLGM
>CP026649.1|AVD57226.1|2921288_2922704_-|ISLre2-family-transposase
MDIISIIAGLLKDTKSLIEFEEQLKLLMQKAFTQWVGEIFEELDKTIKQEKLEEGWVYCRSDNRNIQFLFGSVTFKRSLMHDKRGNSHYPLDEWLGLVPHQRYSPLVELKVAELASENTYREVADILKEWTAVSLSHTTVGNMVKHVGKTQAEADKALVEELEIAVSLPEGKKVDYLFSEADGVFVRGLKKKQSMEVHHAILYEGWQTNGKRVSLRQPTVIMTTEAIQTFWDEVQATAANTYSLEKAHVITNSDGGAGYTAERFQTAFSQSEFPVLNQLDTYHVAQAIIRTFGGGKSEIKEQIRKAIRTHDLDQFTLYLDTHESTLTDKKALKKIKEFRSYILKNWDRIFDWRDRVKNVPEGARGLGAMESNQRHISFRMKKRGMHWSELGAEAMVKIKQGILNGTLREAYLKHRSRSERKQRNLKQSIRMSQLLKQPVRPSVGVKHGSVALHSSSSSAMGHLSKILELSF

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Crispr_ID: CP026649_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026649_13

3575886-3575976

Orphan

Consensus_repeat	Method
CCATATAATAAAAAAGCACTCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026649_13

>merge|CP026649|13|3575886-3575976|CRISPRCasFinder
CCATATAATAAAAAAGCACTCGATGGGCTACATAGCTTGAACAGGCACGAAATCGGGGGTTAGGTGAACCATATAATAAAAAAGCACTACG

>CP026649|13|9|3575886-3575976|CRISPRCasFinder
CCATATAATAAAAAAGCACTCGA	TGGGCTACATAGCTTGAACAGGCACGAAATCGGGGGTTAGGTGAA
CCATATAATAAAAAAGCACTACG

Protein	Signature genes	Signature genes Name	Protein_function
CP026649.1\|AVD57752.1\|3583964_3584252_-\|30S-ribosomal-protein-S6	unknown	unknown	gnl\|CDD\|179034
CP026649.1\|AVD57740.1\|3570165_3570960_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224156
CP026649.1\|AVD57741.1\|3570976_3573028_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369363
CP026649.1\|AVD57747.1\|3579577_3580021_-\|50S-ribosomal-protein-L9	unknown	unknown	gnl\|CDD\|234659
CP026649.1\|AVD57737.1\|3566181_3566448_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368835
CP026649.1\|AVD57751.1\|3583408_3583903_-\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|168659
CP026649.1\|AVD57735.1\|3565468_3565801_+\|DUF1048-domain-containing-protein	unknown	unknown	gnl\|CDD\|368835
CP026649.1\|AVD57736.1\|3565834_3566185_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227154
CP026649.1\|AVD57744.1\|3576287_3576542_-\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD57734.1\|3565128_3565485_+\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
CP026649.1\|AVD57746.1\|3578002_3579358_-\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|180232
CP026649.1\|AVD57739.1\|3568685_3569948_-\|serine-protease	unknown	unknown	gnl\|CDD\|273938
CP026649.1\|AVD57742.1\|3573024_3574845_-\|cell-wall-metabolism-sensor-histidine-kinase-WalK	unknown	unknown	gnl\|CDD\|380161
CP026649.1\|AVD57738.1\|3568328_3568526_+\|hypothetical-protein	unknown	unknown	unknown
CP026649.1\|AVD57749.1\|3582026_3582974_-\|DUF2232-domain-containing-protein	unknown	unknown	gnl\|CDD\|370773
CP026649.1\|AVD57743.1\|3574849_3575560_-\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|223816
CP026649.1\|AVD57753.1\|3584505_3584976_-\|6,7-dimethyl-8-ribityllumazine-synthase	unknown	unknown	gnl\|CDD\|234606
CP026649.1\|AVD57750.1\|3583124_3583364_-\|30S-ribosomal-protein-S18	unknown	unknown	gnl\|CDD\|178997
CP026649.1\|AVD57748.1\|3580017_3581991_-\|DHH-family-phosphoesterase	unknown	unknown	gnl\|CDD\|226404
CP026649.1\|AVD57745.1\|3576538_3577828_-\|adenylosuccinate-synthase	unknown	unknown	gnl\|CDD\|234904

Protein	Function_ID	Function_description	E-value
CP026649.1\|AVD57752.1\|3583964_3584252_-\|30S-ribosomal-protein-S6	gnl\|CDD\|179034	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed.	1.01619e-40
CP026649.1\|AVD57740.1\|3570165_3570960_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224156	COG1235, PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only].	2.41913e-71
CP026649.1\|AVD57741.1\|3570976_3573028_-\|hypothetical-protein	gnl\|CDD\|369363	pfam07435, YycH, YycH protein. This family contains the bacterial protein YycH which is approximately 450 residues long. YycH plays a role in signal transduction and is found immediately downstream of the essential histidine kinase YycG. YycG forms a two component system together with its cognate response regulator YycF. PhoA fusion studies have shown that YycH is transported across the cytoplasmic protein. It is postulated that YycH functions as an antagonist to YycG. The molecule is made up of three domains, and has a novel three-dimensional structure. The N-terminal domain features a calcium binding site and the central domain contains two conserved loop regions.	2.97115e-76
CP026649.1\|AVD57749.1\|3582026_3582974_-\|DUF2232-domain-containing-protein	gnl\|CDD\|370773	pfam09991, DUF2232, Predicted membrane protein (DUF2232). This family of bacterial proteins are multi-pass membrane proteins with up to 10 (2 x 4/5) transmembrane regions. The exact function of this potential pore molecule is not known, but in many instances it is associated with ABC-transporter-like domains, implying that it is part of a secretion system that uses energy.	9.96902e-43
CP026649.1\|AVD57737.1\|3566181_3566448_+\|hypothetical-protein	gnl\|CDD\|368835	pfam06304, DUF1048, Protein of unknown function (DUF1048). This family consists of several hypothetical bacterial proteins of unknown function.	1.50146e-37
CP026649.1\|AVD57751.1\|3583408_3583903_-\|single-stranded-DNA-binding-protein	gnl\|CDD\|168659	PRK06751, PRK06751, single-stranded DNA-binding protein; Provisional.	9.81725e-74
CP026649.1\|AVD57735.1\|3565468_3565801_+\|DUF1048-domain-containing-protein	gnl\|CDD\|368835	pfam06304, DUF1048, Protein of unknown function (DUF1048). This family consists of several hypothetical bacterial proteins of unknown function.	5.88503e-38
CP026649.1\|AVD57736.1\|3565834_3566185_+\|hypothetical-protein	gnl\|CDD\|227154	COG4817, COG4817, DNA-binding ferritin-like protein (Dps family) [General function prediction only].	2.81219e-41
CP026649.1\|AVD57747.1\|3579577_3580021_-\|50S-ribosomal-protein-L9	gnl\|CDD\|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	9.80627e-66
CP026649.1\|AVD57734.1\|3565128_3565485_+\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	4.26915e-26
CP026649.1\|AVD57746.1\|3578002_3579358_-\|replicative-DNA-helicase	gnl\|CDD\|180232	PRK05748, PRK05748, replicative DNA helicase; Provisional.	0
CP026649.1\|AVD57739.1\|3568685_3569948_-\|serine-protease	gnl\|CDD\|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	3.70913e-90
CP026649.1\|AVD57742.1\|3573024_3574845_-\|cell-wall-metabolism-sensor-histidine-kinase-WalK	gnl\|CDD\|380161	NF033092, HK_WalK, cell wall metabolism sensor histidine kinase WalK. This model describes WalK as found in Staphylococcus aureus (sp\|Q2G2U4.1\|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.	0
CP026649.1\|AVD57743.1\|3574849_3575560_-\|DNA-binding-response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.68549e-100
CP026649.1\|AVD57753.1\|3584505_3584976_-\|6,7-dimethyl-8-ribityllumazine-synthase	gnl\|CDD\|234606	PRK00061, ribH, 6,7-dimethyl-8-ribityllumazine synthase; Provisional.	6.10782e-87
CP026649.1\|AVD57750.1\|3583124_3583364_-\|30S-ribosomal-protein-S18	gnl\|CDD\|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	6.9465e-42
CP026649.1\|AVD57748.1\|3580017_3581991_-\|DHH-family-phosphoesterase	gnl\|CDD\|226404	COG3887, COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms].	0
CP026649.1\|AVD57745.1\|3576538_3577828_-\|adenylosuccinate-synthase	gnl\|CDD\|234904	PRK01117, PRK01117, adenylosuccinate synthetase; Provisional.	0

>CP026649.1|AVD57743.1|3574849_3575560_-|DNA-binding-response-regulator
MDKKILVVDDEKPIADILQFNLTKEGYTVYCAYDGEEALEKVEEVQPDLIVLDIMLPKRDGMEVCREVRKKYNMPIIMVTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHQQTPAAPGEEEESNEIAIGSLVIHPDAYVVSKRGETIELTHREFELLHYLAKHIGQVMTREHLLETVWGYDYYGDVRTVDVTVRRLREKVEDNPSHPEWIVTRRGVGYYLRNPEQE
>CP026649.1|AVD57742.1|3573024_3574845_-|cell-wall-metabolism-sensor-histidine-kinase-WalK
MNKVKFFQSIHFKFVLIYILLIVVAMEIIGVYFINKLENQLETNFKKSIYDQVNVLEYSIEDLLTKKQNQAADITLKVRKVLGDFKSTDVSEIRLIDAHSGVILGTSSNDQSIVGQKTTEDIVKSVRVTGQPEDQIYLDKQTGDRMWVLASPIKANGELIGIIYLVSKIETVYRQVQAINQIFMTGTVIAVLVTALLGIITARTISKPLSEIRKQAMAMARGNFARKVKVIGNDEIGQLAYSFNHMTKKLQEAQASTEGERRKLDSILTHMTDGVIATDRRGRIILINEPAAEMLDVSRETVLSQPLISVLKIENEHKFDDLLTEQDSVILDFSTEEEPYILRANFSVIQNEAGFVSGLITVLHDVTEQEKIDMERREFVANVSHELRTPLTTMRSYLEALTDGAWKDEKIAPQFLGVTQNETERMIRLVNDLLKLSKMDSKDEHLNKEWVNFVEFFHHVIDRFEMAKQQNVTFKRKLPNTEIFVEIDEDKMTQVLYNIISNALKYSPEGGQITFKLRELNEKIEVSISDQGVGIPKENVKKIFERFYRVDKARSRKLGGTGLGLAIAKEMVEMHGGSIWASSKEGKGTTIYFTLPYEPAQEDEWL
>CP026649.1|AVD57741.1|3570976_3573028_-|hypothetical-protein
MSLEKAKTIILTLLVLLSLLLTWLIWNNQPNYDLLNLKDLDNIAIAKEKKVPGIILPDKILYHENDGTTGTVHDGEISRVMNLLRTWTFDMSSSRLLQKKDLYNLMYGKNRIELDFPAPVPFSVYQSVLNFANKKVPDADFDHIVIELNKGTKNLNHVYFISTASNKVYEASTDQKSIQVFISKLNDNKSLYKPYTAFALSGPRRIYLPAGNPVVNQYKYATTDIEIDKFKKALFADPNFVKKVAGEYTNGISLLRTDESNKVLTFVNPGEDIGYSSDPNHLLTRAIDFINQHSGWTDQYQYFEINERENEVTFRLFKDGYPVFNDDGMAEIREYLGRSEIYKYVRPYFNLSLNLPLKPAAVKLPPAQDVIAGLQTNPSVQMNKVRDIAVGYRLQKDSDDILSLQPAWYYCEDGIWKMAGGMKMDWSKTKTIFILVFLVLDIYLSCQLYFKHVKNQYEVIGSPTAEQSLKAANITFVNLPKGKAKRPYISAEEKVFTAKDLKKLKNQQAEIVNGYQLSSAFDKPVKLGTKIKTDQLEAVIQENMLYGSRYKLWNYDKDLNQAVFYETYNGKMIFNNKNAKLTVYLNDQNEIISYDQTYLTNIKIYREEEETLSAVKAVEALYKKGTLKPNSKVTKAELGYYTRVPELQVLVPTWHFTVKHGNETEQLFINAFEGQVNEMENAQ
>CP026649.1|AVD57740.1|3570165_3570960_-|MBL-fold-metallo-hydrolase
MGMQFSVLASGSTGNAIYVETEQHAFLVDAGLSGRQMEQLFGQIGRNIADLSGILVTHEHSDHIKGIGVLARKYKLPIYANDKTWSAMEGMIGEIPTDLKFSFGMESVQSFGSLEIESFGVSHDAVQPMFYIFHEGGKKLVIITDTGYVSDRMKGTISNADIFVFESNHDVEMLRMGRYPWSVKQRILSDVGHVSNEDAALAMSEVIGDRTKRIYLAHLSKDNNMKDLARMAVSQTLQEQGLAVGETFSLYDTDPKIPTALTAV
>CP026649.1|AVD57739.1|3568685_3569948_-|serine-protease
MGYYDDQDGQRRGKENRRSGGKFGYFLSGLIGVIVGALVVALLFPNIFGKTNSDSSAVDSNSVANTSTSTAKTTKTVSLKVTTDITKAVEKTEKAVVGVSNIQKQSIWSDDMFGQDSKSSSSSSQEAGSGSGIIYKKAGDKAYVVTNYHVIEGANALEVTLSNGKKLSAKLVGGDKYTDLAVLQIDGSNVTTVAQFGDSDALKLGESVIAIGNPLGEEFAGSVTEGIVSGLNRTVPVDIDEDGTEDWQEEVIQTDAAINPGNSGGALINISGQVVGINSMKISNESVEGIGFSIPINSAKPVIHQLETKGKITRPAMGVGIVNVSDISAYQQQETLKLPTNVTTGVVIGSVENGSPAGKVGLKEFDVIYKLDNQKIDNTVELRKYLYEHKQPGDKVKVSVYRNGQPKTFTLTLGTASGSN
>CP026649.1|AVD57738.1|3568328_3568526_+|hypothetical-protein
MPCFKYFSFNFPTVTIEIFTTYTHLTHKLLTRVIHISTETIHILCGNNRSIQDIFHHFSLFTACL
>CP026649.1|AVD57737.1|3566181_3566448_+|hypothetical-protein
MNIKNIIEGKKEWRAHVARVKALPQDYQIVYKEIQKYLFKVGVVEVNESIGLLSEILNFFEESAAAGKGVLEVTGPDVAAFCDALIEG
>CP026649.1|AVD57736.1|3565834_3566185_+|hypothetical-protein
MNFFEKITGSDMTKAIKSFEARAKVLPAEYQTAWNEIKSNLWVYGNFTGRNLMPILDNALELLEVASADKQSIEEVLEDDIKGFCAALVGEGAKTYRDKWREQLNRNAARKLGGLK
>CP026649.1|AVD57735.1|3565468_3565801_+|DUF1048-domain-containing-protein
MSILDKIFGDFNEKKAWREMEKRAKALPEDYYNAYKAMQKYLWNTGGVMDWQETKFVFTHIIELLEEAAANGKRVKEVTGDDVAAFCDDLAIDAKSWIDKQRQKLNDAIK
>CP026649.1|AVD57734.1|3565128_3565485_+|PadR-family-transcriptional-regulator
MENITEMLKGVLEGCVLEIISRGETYGYEITQRLRKLGFTDVVEGTVYTITMRLEKKNLVNVEKKPSTMGPPRKFYTLNEAGQEQLEIFWRKWEFISSKMNELKKFNQKEKPSNEHFG
>CP026649.1|AVD57744.1|3576287_3576542_-|hypothetical-protein
MTENPDESDLGCRKNGSGTTSKRKPMKKHHRVRLLKAIFIPECPLERKKRRDPIKGVSRRFYIVLKWVMIFHLLRRPCLKMNIC
>CP026649.1|AVD57745.1|3576538_3577828_-|adenylosuccinate-synthase
MSSVVVVGTQWGDEGKGKITDFLSENAEVVSRYQGGNNAGHTIRFNGETYKLHLIPSGIFYKDKICVIGNGVVVDPKALVEELDYLNGRGISTENLRISNRAHVILPYHIKLDGAEEERKGSNKIGTTKKGIGPAYMDKAARTGIRIADLLDYEEFKEKLTRNLEEKNRLFEKIYETEGFTLEEILEPYYEYGQRFKQYVCDTSVVLNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSSNPIAGGVTIGSGVGPSKINHVVGIAKAYTTRVGDGPFPTELLDETGDRIRETGHEYGTTTGRARRVGWFDSVVVRHARRVSGLTDLSVNLLDVLTGIETLKICVAYRYKGKVLEAFPASLKVLAECEPVYEELPGWTEDITGCRSLDELPDNARHYLERISQLTGVPLSMFSVGPDRLQTIVVQSVWRV
>CP026649.1|AVD57746.1|3578002_3579358_-|replicative-DNA-helicase
MNELQDRIPPQNIEAEQAVLGAIFLEPSAFITASEILTAEDFYRNAHQKIFQVFAKLNDAGKAVDLVTVAEELSATRQLEDAGGLSYLSELAASVPTAANIAYYAGIVAEKALLRRLIRTATHIAQEGYTREDDVDELLDEAERSIMEVAQRKNAGDFKHIKDVLVSTYDNIEMLHNRKGDVTGIPTGFYELDRMTAGFQRNDLIIVAARPSVGKTAFALNIAQNVGTKTEENVAIFSLEMGAEQLVMRMLCAEGNIDAQRLRTGALTDEDWRKLTMAMGSLSNSGIYIDDTPGVRVTEIRSKCRRLKQEHGLGMVVIDYLQLIQGSARSRENRQQEVSEISRSLKALARELEVPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYREDYYEQDTENKNIIEIIIAKQRNGPVGTVQLAFIKEYNKFVNLERRFDDAPVPA
>CP026649.1|AVD57747.1|3579577_3580021_-|50S-ribosomal-protein-L9
MKVIFLKDVKGKGKKGDIKNVADGYAHNYLFKNGAAIEATPANLKSMEAQKRKEEKLAQEELEEAKKLKEKLENITVEIKAKSGQDGRLFGSVTSKQISEQLKKSFQIQVDKRKIELPDAIRTLGYTKVPVRLHHNVTAVLNVHVSE
>CP026649.1|AVD57748.1|3580017_3581991_-|DHH-family-phosphoesterase
MPSYYNKRFMRYPLYGLIAVSLILLGIIFFYHWWITAAGIVVLGALSYCAFYVEQRSSEEIERYISNLSYRVKRVGEEALMEMPIGIMLYNEDYIIEWTNPFMASCFNEDTLVGRSLYDVAEVLVPLIKQEMHSETISLNERKYRVVLKLEERLLYFFDITEQAEVEQLYEDERTVIAIIYLDNYDEVTQGMDDQSVSSLNSLVTSILNKWTMEFGLFFKRISSDKFIAVFNERILHELEDNKFSILDEVREATAKQNVALTLSIGVGAGVPSLPELGELAQSSLDIALGRGGDQVAIRQANGKVKFYGGKTNPVEKRTRVRARVISHALRELMMERDKVMIMGHKFPDMDAIGAAVGIRKVAEINQKDGYIILNPSETDTSVKRLLGEIKQYPDLYARFITPDEALEMATDDTLLVVVDTHKPSFVIDERIVRRIENVVVIDHHRRGEDFIKNPLLVYMEPYASSTSELVTELMEYQPKNGKINMLEATALLAGIIVDTKSFTLRTGSRTFDAASYLRAQGADTVLVQKFLKEDLRSYIQRAKLVETVKFPLNGIAVAKGKNDTIYSPVLMAQAADTILMMNGVDASFVIGRRSENEVGISARSLGSVNVQIIMETLDGGGHLSNAATQMKNITVDEAEEKLIQVIEEYMEGSQQS
>CP026649.1|AVD57749.1|3582026_3582974_-|DUF2232-domain-containing-protein
MRVKKTRMLTEGAMLAAVFGVMLLVALHVPVIRIIVLVFLPLPFILFCAKYSLRSILVFCLVCLLVSAIMGTVMAIPMAVFFVCIGFVMGYAIQRKKSKLFIYIATSLTFLAITIIGLFATLKFFHLNIIAENLKIMQQSIEQSKALVNSLGESQAYEDRFAQMADVASQMYSVYLPSLLLLSAFIAVFVLISVNFPIAKRFGVPVPSFQPFREMRLPGNILWYFILAMVANLLMHGDTGSFFAKAVLNLMLIFQILILLQGYAFISFVSHEKKWPKGLLAFAVILSIIFSPLLYLVMIFGIMDLGFDFRRMIQK
>CP026649.1|AVD57750.1|3583124_3583364_-|30S-ribosomal-protein-S18
MAGGRRGGRKRRKVCYFTANHITHIDYKDVDLLKKFISERGKILPRRVTGTSAKYQRKLTTAIKRARQMALLPYVAEDK
>CP026649.1|AVD57751.1|3583408_3583903_-|single-stranded-DNA-binding-protein
MLNRVVLVGRLTKDPDLRYTPSGVAVATFTLAVNRTFTNQQGEREADFINCVVWRKQAENVANYLKKGSLAGVDGRIQTRNYEAQDGRRVYVTEVVADSVQFLEPRSANQERGSSQNYGNNQGSAFPGYNQNQNQYQRNDSKPDEDPFSNDGQPIDISDDDLPF
>CP026649.1|AVD57752.1|3583964_3584252_-|30S-ribosomal-protein-S6
MRKYEIMYIIRPNIEDEAKKALVERFDNVLNNQGAEIIESKEWGKRRLAYEIQDFRDGYYHIINVNAEPVAVQEFDRLAKINGDIIRHIVVREEE
>CP026649.1|AVD57753.1|3584505_3584976_-|6,7-dimethyl-8-ribityllumazine-synthase
MGQIFEGNLVGTGLKIGMVAARFNEFITTRLVSGAKDALLRHGVKEEAIDLAWVPGAFEIPLAAKKMAETDKYDAVLALGAVIRGATPHFEYVSAEAAKGVAHASLSTETPVIFGILTTDTIEQAIERAGTKAGNKGWDAAVSAIEMANVIRKIEA

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP026649_3	3.2\|430700\|19\|CP026649\|CRT	430700-430718	19	CP026649.1	91248-91266	2	0.895
CP026649_3	3.6\|430908\|19\|CP026649\|CRT	430908-430926	19	CP026649.1	1944137-1944155	2	0.895

1. spacer 3.2|430700|19|CP026649|CRT matches to position: 91248-91266, mismatch: 2, identity: 0.895

gggcccggatgcagctcgt	CRISPR spacer
ggacccggatgcagcttgt	Protospacer
**.*************.**

2. spacer 3.6|430908|19|CP026649|CRT matches to position: 1944137-1944155, mismatch: 2, identity: 0.895

attcccggatgcggcacgt	CRISPR spacer
attcccggatgccgaacgt	Protospacer
************ * ****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP026649_12	12.24\|2906906\|35\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2906906-2906940	35	NZ_CP035407	Bacillus subtilis strain SRCM103612 plasmid unnamed1	34087-34121	1	0.971
CP026649_12	12.24\|2906906\|35\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2906906-2906940	35	MT366947	Bacillus phage Hyb2phi3Ts-SPbeta, complete genome	116835-116869	1	0.971
CP026649_12	12.24\|2906906\|35\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2906906-2906940	35	KY030782	Bacillus phage phi3T, complete genome	116504-116538	1	0.971
CP026649_12	12.24\|2906906\|35\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2906906-2906940	35	NC_001884	Bacillus phage SPBc2, complete genome	125867-125901	1	0.971
CP026649_12	12.24\|2906906\|35\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2906906-2906940	35	AF020713	Bacteriophage SPBc2 complete genome	125867-125901	1	0.971
CP026649_12	12.24\|2906906\|35\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2906906-2906940	35	MT366946	Bacillus phage Hyb1phi3Ts-SPbeta, complete genome	118684-118718	1	0.971
CP026649_12	12.24\|2906906\|35\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2906906-2906940	35	MT366948	Bacillus phage Hyb3phi3Ts-SPbeta, complete genome	115582-115616	1	0.971
CP026649_12	12.24\|2906906\|35\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2906906-2906940	35	MT366945	Bacillus phage phi3Ts, complete genome	115969-116003	1	0.971
CP026649_12	12.31\|2907367\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2907367-2907399	33	GQ478087	Enterococcus phage phiFL3B, complete genome	32991-33023	2	0.939
CP026649_12	12.31\|2907367\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2907367-2907399	33	NC_013648	Enterococcus phage phiFL3A, complete genome	32292-32324	2	0.939
CP026649_6	6.4\|976075\|33\|CP026649\|CRT	976075-976107	33	NC_012520	Rhodococcus opacus B4 plasmid pROB01, complete sequence	239385-239417	6	0.818
CP026649_10	10.1\|2419397\|55\|CP026649\|CRISPRCasFinder	2419397-2419451	55	NZ_LR134399	Listeria monocytogenes strain NCTC7974 plasmid 2, complete sequence	57355-57409	6	0.891
CP026649_10	10.1\|2419397\|55\|CP026649\|CRISPRCasFinder	2419397-2419451	55	NZ_CP015440	Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_2, complete sequence	64784-64838	7	0.873
CP026649_12	12.52\|2908752\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2908752-2908785	34	MG788324	Lactobacillus phage PM411, complete genome	27603-27636	7	0.794
CP026649_6	6.5\|976127\|33\|CP026649\|CRT	976127-976159	33	NZ_CP032692	Rhizobium sp. CCGE532 plasmid pRCCGE532b, complete sequence	4611-4643	8	0.758
CP026649_10	10.1\|2419397\|55\|CP026649\|CRISPRCasFinder	2419397-2419451	55	NZ_CP015439	Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_1, complete sequence	255881-255935	8	0.855
CP026649_12	12.35\|2907629\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2907629-2907662	34	AP014353	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S39-C37, * SEQUENCING IN PROGRESS *	26205-26238	8	0.765
CP026649_10	10.1\|2419397\|55\|CP026649\|CRISPRCasFinder	2419397-2419451	55	NZ_CP024037	Bacillus aryabhattai strain K13 plasmid unnamed2	10428-10482	9	0.836
CP026649_10	10.1\|2419397\|55\|CP026649\|CRISPRCasFinder	2419397-2419451	55	NZ_CP026740	Bacillus megaterium strain YC4-R4 plasmid unnamed4	70775-70829	9	0.836
CP026649_10	10.1\|2419397\|55\|CP026649\|CRISPRCasFinder	2419397-2419451	55	NZ_CP010587	Bacillus megaterium Q3 plasmid p1, complete sequence	832-886	9	0.836
CP026649_10	10.1\|2419397\|55\|CP026649\|CRISPRCasFinder	2419397-2419451	55	NZ_CP023319	Bacillus megaterium strain A plasmid p2, complete sequence	75819-75873	9	0.836
CP026649_10	10.1\|2419397\|55\|CP026649\|CRISPRCasFinder	2419397-2419451	55	NC_017139	Bacillus megaterium WSH-002 plasmid WSH-002_p1, complete sequence	1329-1383	9	0.836
CP026649_10	10.1\|2419397\|55\|CP026649\|CRISPRCasFinder	2419397-2419451	55	NC_020451	Vibrio coralliilyticus strain ATCC BAA-450 plasmid, complete sequence	1971-2025	9	0.836
CP026649_12	12.6\|2905714\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905714-2905747	34	NC_014792	Enterobacteria phage vB_EcoM-VR7, complete genome	108180-108213	9	0.735
CP026649_12	12.6\|2905714\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905714-2905747	34	KP007359	Enterobacteria phage vB_EcoM_VR5, complete genome	108026-108059	9	0.735
CP026649_12	12.9\|2905914\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905914-2905947	34	NZ_CP025980	Escherichia marmotae strain HT073016 plasmid pEM148, complete sequence	85025-85058	9	0.735
CP026649_12	12.28\|2907173\|32\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2907173-2907204	32	JX238501	Bacillus phage phiAGATE, complete genome	112994-113025	9	0.719
CP026649_12	12.53\|2908818\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2908818-2908851	34	NC_029057	Vibrio phage qdvp001, partial genome	73144-73177	9	0.735
CP026649_12	12.53\|2908818\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2908818-2908851	34	AP013545	Uncultured phage_MedDCM-OCT-S46-C10 DNA, complete genome, group G8, isolate: uvMED-CGR-U-MedDCM-OCT-S46-C10	31001-31034	9	0.735
CP026649_10	10.1\|2419397\|55\|CP026649\|CRISPRCasFinder	2419397-2419451	55	NC_048753	Lactobacillus phage 3-521, complete genome	13549-13603	10	0.818
CP026649_12	12.4\|2905583\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905583-2905615	33	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	456028-456060	10	0.697
CP026649_12	12.4\|2905583\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905583-2905615	33	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	634797-634829	10	0.697
CP026649_12	12.4\|2905583\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905583-2905615	33	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	456044-456076	10	0.697
CP026649_12	12.4\|2905583\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905583-2905615	33	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	455800-455832	10	0.697
CP026649_12	12.4\|2905583\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905583-2905615	33	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	455796-455828	10	0.697
CP026649_12	12.4\|2905583\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905583-2905615	33	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	431458-431490	10	0.697
CP026649_12	12.4\|2905583\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905583-2905615	33	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	408639-408671	10	0.697
CP026649_12	12.4\|2905583\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905583-2905615	33	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1664627-1664659	10	0.697
CP026649_12	12.4\|2905583\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905583-2905615	33	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1664660-1664692	10	0.697
CP026649_12	12.4\|2905583\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905583-2905615	33	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1546541-1546573	10	0.697
CP026649_12	12.4\|2905583\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905583-2905615	33	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1418050-1418082	10	0.697
CP026649_12	12.4\|2905583\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905583-2905615	33	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1664625-1664657	10	0.697
CP026649_12	12.4\|2905583\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2905583-2905615	33	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1530018-1530050	10	0.697
CP026649_12	12.34\|2907564\|33\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2907564-2907596	33	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1794917-1794949	10	0.697
CP026649_12	12.46\|2908356\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2908356-2908389	34	MN694676	Marine virus AFVG_250M673, complete genome	30208-30241	10	0.706
CP026649_12	12.53\|2908818\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2908818-2908851	34	MH299806	Listeria phage LP-KV022, complete genome	42920-42953	10	0.706
CP026649_12	12.53\|2908818\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2908818-2908851	34	JB137888	Sequence 7 from Patent WO2012159774	9940-9973	10	0.706
CP026649_12	12.53\|2908818\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2908818-2908851	34	MN114083	Listeria phage LP-013, complete genome	37958-37991	10	0.706
CP026649_12	12.53\|2908818\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2908818-2908851	34	NC_021785	Listeria phage LP-110, complete genome	638-671	10	0.706
CP026649_12	12.53\|2908818\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2908818-2908851	34	KJ094024	Listeria phage LP-032 contig 1, partial genome	5703-5736	10	0.706
CP026649_12	12.53\|2908818\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2908818-2908851	34	NC_021787	Listeria phage LP-037, complete genome	60324-60357	10	0.706
CP026649_12	12.53\|2908818\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2908818-2908851	34	MN904502	Listeria phage LP-018, complete genome	37411-37444	10	0.706
CP026649_12	12.53\|2908818\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2908818-2908851	34	KJ094020	Listeria phage LP-026, complete genome	20419-20452	10	0.706
CP026649_10	10.1\|2419397\|55\|CP026649\|CRISPRCasFinder	2419397-2419451	55	NZ_CP033045	Bacillus foraminis strain Bac44 plasmid unnamed, complete sequence	483785-483839	11	0.8
CP026649_12	12.38\|2907827\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2907827-2907860	34	NZ_CP028971	Aminobacter sp. MSH1 plasmid pUSP3, complete sequence	55170-55203	11	0.676
CP026649_12	12.46\|2908356\|34\|CP026649\|CRT,PILER-CR,CRISPRCasFinder	2908356-2908389	34	KC821606	Cellulophaga phage phi12:2, complete genome	2518-2551	11	0.676

1. spacer 12.24|2906906|35|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP035407 (Bacillus subtilis strain SRCM103612 plasmid unnamed1) position: , mismatch: 1, identity: 0.971

ttttgcggaatttcaccgcctatgcgatagtcgtt	CRISPR spacer
ttttgcggaatttcgccgcctatgcgatagtcgtt	Protospacer
**************.********************

2. spacer 12.24|2906906|35|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to MT366947 (Bacillus phage Hyb2phi3Ts-SPbeta, complete genome) position: , mismatch: 1, identity: 0.971

ttttgcggaatttcaccgcctatgcgatagtcgtt	CRISPR spacer
ttttgcggaatttcgccgcctatgcgatagtcgtt	Protospacer
**************.********************

3. spacer 12.24|2906906|35|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to KY030782 (Bacillus phage phi3T, complete genome) position: , mismatch: 1, identity: 0.971

ttttgcggaatttcaccgcctatgcgatagtcgtt	CRISPR spacer
ttttgcggaatttcgccgcctatgcgatagtcgtt	Protospacer
**************.********************

4. spacer 12.24|2906906|35|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NC_001884 (Bacillus phage SPBc2, complete genome) position: , mismatch: 1, identity: 0.971

ttttgcggaatttcaccgcctatgcgatagtcgtt	CRISPR spacer
ttttgcggaatttcgccgcctatgcgatagtcgtt	Protospacer
**************.********************

5. spacer 12.24|2906906|35|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to AF020713 (Bacteriophage SPBc2 complete genome) position: , mismatch: 1, identity: 0.971

ttttgcggaatttcaccgcctatgcgatagtcgtt	CRISPR spacer
ttttgcggaatttcgccgcctatgcgatagtcgtt	Protospacer
**************.********************

6. spacer 12.24|2906906|35|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to MT366946 (Bacillus phage Hyb1phi3Ts-SPbeta, complete genome) position: , mismatch: 1, identity: 0.971

ttttgcggaatttcaccgcctatgcgatagtcgtt	CRISPR spacer
ttttgcggaatttcgccgcctatgcgatagtcgtt	Protospacer
**************.********************

7. spacer 12.24|2906906|35|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to MT366948 (Bacillus phage Hyb3phi3Ts-SPbeta, complete genome) position: , mismatch: 1, identity: 0.971

ttttgcggaatttcaccgcctatgcgatagtcgtt	CRISPR spacer
ttttgcggaatttcgccgcctatgcgatagtcgtt	Protospacer
**************.********************

8. spacer 12.24|2906906|35|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to MT366945 (Bacillus phage phi3Ts, complete genome) position: , mismatch: 1, identity: 0.971

ttttgcggaatttcaccgcctatgcgatagtcgtt	CRISPR spacer
ttttgcggaatttcgccgcctatgcgatagtcgtt	Protospacer
**************.********************

9. spacer 12.31|2907367|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to GQ478087 (Enterococcus phage phiFL3B, complete genome) position: , mismatch: 2, identity: 0.939

gtcaaatccattaaaaatgttcccatgacctgg	CRISPR spacer
gtcaaatccattaaaaatatttccatgacctgg	Protospacer
******************.**.***********

10. spacer 12.31|2907367|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NC_013648 (Enterococcus phage phiFL3A, complete genome) position: , mismatch: 2, identity: 0.939

gtcaaatccattaaaaatgttcccatgacctgg	CRISPR spacer
gtcaaatccattaaaaatatttccatgacctgg	Protospacer
******************.**.***********

11. spacer 6.4|976075|33|CP026649|CRT matches to NC_012520 (Rhodococcus opacus B4 plasmid pROB01, complete sequence) position: , mismatch: 6, identity: 0.818

gatggctgccagtattctgtccttca-ccggcat	CRISPR spacer
tgcggctgccagtagtcagtccttcacccggca-	Protospacer
 ..*********** ** ******** ******

12. spacer 10.1|2419397|55|CP026649|CRISPRCasFinder matches to NZ_LR134399 (Listeria monocytogenes strain NCTC7974 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.891

cgacaacagcttggaaggctgtggttttaccactaaactacacccgcagcaaagg	CRISPR spacer
cgacaacagcttggaaggctgtagttttaccactaaactacacccgcatagtaag	Protospacer
**********************.*************************  . *.*

13. spacer 10.1|2419397|55|CP026649|CRISPRCasFinder matches to NZ_CP015440 (Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_2, complete sequence) position: , mismatch: 7, identity: 0.873

cgacaacagcttggaaggctgtggttttaccactaaactacacccgcagcaaagg	CRISPR spacer
cgacatcagcttggaaggctgaggttttaccactaaactacacccgcataataat	Protospacer
***** *************** **************************  * *.

14. spacer 12.52|2908752|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to MG788324 (Lactobacillus phage PM411, complete genome) position: , mismatch: 7, identity: 0.794

ttgtgcttttagtgattcgttttcatcacgaaca-	CRISPR spacer
ttgtgctttttgtgattctttttc-caaggaactt	Protospacer
********** ******* ***** . * ****

15. spacer 6.5|976127|33|CP026649|CRT matches to NZ_CP032692 (Rhizobium sp. CCGE532 plasmid pRCCGE532b, complete sequence) position: , mismatch: 8, identity: 0.758

cgcagctgccagccatttgtccttcatctgccc	CRISPR spacer
gcccgctgccagccatttgtcgatcatccgtcg	Protospacer
  * *****************  *****.*.*

16. spacer 10.1|2419397|55|CP026649|CRISPRCasFinder matches to NZ_CP015439 (Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_1, complete sequence) position: , mismatch: 8, identity: 0.855

cgacaacagcttggaaggctgtggttttaccactaaactacacccgcagcaaagg	CRISPR spacer
cgacatcagcttggaaggctgaggttttaccactaaactacacccgcatattata	Protospacer
***** *************** **************************    * .

17. spacer 12.35|2907629|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to AP014353 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S39-C37, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.765

ttggctcgatcagcttacaaatcaatttagcgca	CRISPR spacer
gcgactcgatcatcttgcaaatcaattttacgaa	Protospacer
 .*.******** ***.*********** .** *

18. spacer 10.1|2419397|55|CP026649|CRISPRCasFinder matches to NZ_CP024037 (Bacillus aryabhattai strain K13 plasmid unnamed2) position: , mismatch: 9, identity: 0.836

cgacaacagcttggaaggctgtggttttaccactaaactacacccgcagcaaagg	CRISPR spacer
cgacatcagcttggaaggctgaggttttaccactaaactacacccgcatatttta	Protospacer
***** *************** **************************      .

19. spacer 10.1|2419397|55|CP026649|CRISPRCasFinder matches to NZ_CP026740 (Bacillus megaterium strain YC4-R4 plasmid unnamed4) position: , mismatch: 9, identity: 0.836

cgacaacagcttggaaggctgtggttttaccactaaactacacccgcagcaaagg	CRISPR spacer
cgacatcagcttggaaggctgaggttttaccactaaactacacccgcatatttta	Protospacer
***** *************** **************************      .

20. spacer 10.1|2419397|55|CP026649|CRISPRCasFinder matches to NZ_CP010587 (Bacillus megaterium Q3 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.836

cgacaacagcttggaaggctgtggttttaccactaaactacacccgcagcaaagg	CRISPR spacer
cgacatcagcttggaaggctgaggttttaccactaaactacacccgcatatttta	Protospacer
***** *************** **************************      .

21. spacer 10.1|2419397|55|CP026649|CRISPRCasFinder matches to NZ_CP023319 (Bacillus megaterium strain A plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.836

cgacaacagcttggaaggctgtggttttaccactaaactacacccgcagcaaagg	CRISPR spacer
cgacatcagcttggaaggctgaggttttaccactaaactacacccgcatatttta	Protospacer
***** *************** **************************      .

22. spacer 10.1|2419397|55|CP026649|CRISPRCasFinder matches to NC_017139 (Bacillus megaterium WSH-002 plasmid WSH-002_p1, complete sequence) position: , mismatch: 9, identity: 0.836

cgacaacagcttggaaggctgtggttttaccactaaactacacccgcagcaaagg	CRISPR spacer
cgacatcagcttggaaggctgaggttttaccactaaactacacccgcatatttta	Protospacer
***** *************** **************************      .

23. spacer 10.1|2419397|55|CP026649|CRISPRCasFinder matches to NC_020451 (Vibrio coralliilyticus strain ATCC BAA-450 plasmid, complete sequence) position: , mismatch: 9, identity: 0.836

cgacaacagcttggaaggctgtggttttaccactaaactacacccgcagcaaagg	CRISPR spacer
catcatcagcttggaaggctgaggttttaccactaaactacacccgcattttagt	Protospacer
*. ** *************** ************************** .  **

24. spacer 12.6|2905714|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NC_014792 (Enterobacteria phage vB_EcoM-VR7, complete genome) position: , mismatch: 9, identity: 0.735

ctcagggaccacaaggacaacaggggcctgccgg	CRISPR spacer
ttcagggaccacaaggactacaaggagacccggg	Protospacer
.***************** ***.**.  . * **

25. spacer 12.6|2905714|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to KP007359 (Enterobacteria phage vB_EcoM_VR5, complete genome) position: , mismatch: 9, identity: 0.735

ctcagggaccacaaggacaacaggggcctgccgg	CRISPR spacer
ttcagggaccacaaggactacaaggagacccggg	Protospacer
.***************** ***.**.  . * **

26. spacer 12.9|2905914|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP025980 (Escherichia marmotae strain HT073016 plasmid pEM148, complete sequence) position: , mismatch: 9, identity: 0.735

cgtttttccggccaacaaaaaccaaaccttcacg	CRISPR spacer
acactttccggtcaacaaaaacaaaaccttggcc	Protospacer
   .*******.********** ******* .*

27. spacer 12.28|2907173|32|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to JX238501 (Bacillus phage phiAGATE, complete genome) position: , mismatch: 9, identity: 0.719

ggggatattttgtgtttgttcttcaactactg	CRISPR spacer
tttaacattttgtgtcttttcttcaactacaa	Protospacer
   .*.*********.* ************ .

28. spacer 12.53|2908818|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NC_029057 (Vibrio phage qdvp001, partial genome) position: , mismatch: 9, identity: 0.735

acagcacctgtaatttcatttaaagcttcttctg	CRISPR spacer
ccttcttcaataagtttatttaaagcttcttctg	Protospacer
 *  * .* .*** **.*****************

29. spacer 12.53|2908818|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to AP013545 (Uncultured phage_MedDCM-OCT-S46-C10 DNA, complete genome, group G8, isolate: uvMED-CGR-U-MedDCM-OCT-S46-C10) position: , mismatch: 9, identity: 0.735

acagcacctgtaatttcatttaaagcttcttctg	CRISPR spacer
tgtgaagctttaatttcatttaaatcttcttgtc	Protospacer
   * * ** ************** ****** *

30. spacer 10.1|2419397|55|CP026649|CRISPRCasFinder matches to NC_048753 (Lactobacillus phage 3-521, complete genome) position: , mismatch: 10, identity: 0.818

cgacaacagcttggaaggctgtggttttaccactaaactacacccgcagcaaagg	CRISPR spacer
catctacagcttggaaggctgtggttttaccactaaactatacccgcgtgaacta	Protospacer
*. * ***********************************.******.  **  .

31. spacer 12.4|2905583|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ggcataaaacgcgcctatgtgccggacggcatc	CRISPR spacer
ttccagccgcgcgcctatgtgccgggcagcatc	Protospacer
  *  .  .****************.*.*****

32. spacer 12.4|2905583|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 10, identity: 0.697

ggcataaaacgcgcctatgtgccggacggcatc	CRISPR spacer
ttccagccgcgcgcctatgtgccgggcagcatc	Protospacer
  *  .  .****************.*.*****

33. spacer 12.4|2905583|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ggcataaaacgcgcctatgtgccggacggcatc	CRISPR spacer
ttccagccgcgcgcctatgtgccgggcagcatc	Protospacer
  *  .  .****************.*.*****

34. spacer 12.4|2905583|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.697

ggcataaaacgcgcctatgtgccggacggcatc	CRISPR spacer
ttccagccgcgcgcctatgtgccgggcagcatc	Protospacer
  *  .  .****************.*.*****

35. spacer 12.4|2905583|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ggcataaaacgcgcctatgtgccggacggcatc	CRISPR spacer
ttccagccgcgcgcctatgtgccgggcagcatc	Protospacer
  *  .  .****************.*.*****

36. spacer 12.4|2905583|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ggcataaaacgcgcctatgtgccggacggcatc	CRISPR spacer
ttccagccgcgcgcctatgtgccgggcagcatc	Protospacer
  *  .  .****************.*.*****

37. spacer 12.4|2905583|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ggcataaaacgcgcctatgtgccggacggcatc	CRISPR spacer
ttccagccgcgcgcctatgtgccgggcagcatc	Protospacer
  *  .  .****************.*.*****

38. spacer 12.4|2905583|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ggcataaaacgcgcctatgtgccggacggcatc	CRISPR spacer
ttccagccgcgcgcctatgtgccgggcagcatc	Protospacer
  *  .  .****************.*.*****

39. spacer 12.4|2905583|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ggcataaaacgcgcctatgtgccggacggcatc	CRISPR spacer
ttccagccgcgcgcctatgtgccgggcagcatc	Protospacer
  *  .  .****************.*.*****

40. spacer 12.4|2905583|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ggcataaaacgcgcctatgtgccggacggcatc	CRISPR spacer
ttccagccgcgcgcctatgtgccgggcagcatc	Protospacer
  *  .  .****************.*.*****

41. spacer 12.4|2905583|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ggcataaaacgcgcctatgtgccggacggcatc	CRISPR spacer
ttccagccgcgcgcctatgtgccgggcagcatc	Protospacer
  *  .  .****************.*.*****

42. spacer 12.4|2905583|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ggcataaaacgcgcctatgtgccggacggcatc	CRISPR spacer
ttccagccgcgcgcctatgtgccgggcagcatc	Protospacer
  *  .  .****************.*.*****

43. spacer 12.4|2905583|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.697

ggcataaaacgcgcctatgtgccggacggcatc	CRISPR spacer
ttccagccgcgcgcctatgtgccgggcagcatc	Protospacer
  *  .  .****************.*.*****

44. spacer 12.34|2907564|33|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 10, identity: 0.697

ttcagccggtcatggagcagaccggagatttca	CRISPR spacer
gtcagccggtcatgcagcagatcggccagcgtc	Protospacer
 ************* ******.***  * . .

45. spacer 12.46|2908356|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to MN694676 (Marine virus AFVG_250M673, complete genome) position: , mismatch: 10, identity: 0.706

acaacg----ccatttttgcggttgttccgcttcccat	CRISPR spacer
----cgctgaccattttggcggttgttccgtttcatcg	Protospacer
    **    ******* ************.*** .

46. spacer 12.53|2908818|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to MH299806 (Listeria phage LP-KV022, complete genome) position: , mismatch: 10, identity: 0.706

acagcacctgtaatttcatttaaagcttcttctg	CRISPR spacer
tctagtcgtgtaatttcctctaaagcttcttcac	Protospacer
 * .  * ********* *.************

47. spacer 12.53|2908818|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to JB137888 (Sequence 7 from Patent WO2012159774) position: , mismatch: 10, identity: 0.706

acagcacctgtaatttcatttaaagcttcttctg	CRISPR spacer
tctagtcgtgtaatttcctctaaagcttcttcac	Protospacer
 * .  * ********* *.************

48. spacer 12.53|2908818|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to MN114083 (Listeria phage LP-013, complete genome) position: , mismatch: 10, identity: 0.706

acagcacctgtaatttcatttaaagcttcttctg	CRISPR spacer
tctagtcgtgtaatttcctctaaagcttcttcac	Protospacer
 * .  * ********* *.************

49. spacer 12.53|2908818|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NC_021785 (Listeria phage LP-110, complete genome) position: , mismatch: 10, identity: 0.706

acagcacctgtaatttcatttaaagcttcttctg	CRISPR spacer
tctagtcgtgtaatttcctctaaagcttcttcac	Protospacer
 * .  * ********* *.************

50. spacer 12.53|2908818|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to KJ094024 (Listeria phage LP-032 contig 1, partial genome) position: , mismatch: 10, identity: 0.706

acagcacctgtaatttcatttaaagcttcttctg	CRISPR spacer
tctagtcgtgtaatttcctctaaagcttcttcac	Protospacer
 * .  * ********* *.************

51. spacer 12.53|2908818|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NC_021787 (Listeria phage LP-037, complete genome) position: , mismatch: 10, identity: 0.706

acagcacctgtaatttcatttaaagcttcttctg	CRISPR spacer
tctagtcgtgtaatttcctctaaagcttcttcac	Protospacer
 * .  * ********* *.************

52. spacer 12.53|2908818|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to MN904502 (Listeria phage LP-018, complete genome) position: , mismatch: 10, identity: 0.706

acagcacctgtaatttcatttaaagcttcttctg	CRISPR spacer
tctagtcgtgtaatttcctctaaagcttcttcac	Protospacer
 * .  * ********* *.************

53. spacer 12.53|2908818|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to KJ094020 (Listeria phage LP-026, complete genome) position: , mismatch: 10, identity: 0.706

acagcacctgtaatttcatttaaagcttcttctg	CRISPR spacer
tctagtcgtgtaatttcctctaaagcttcttcac	Protospacer
 * .  * ********* *.************

54. spacer 10.1|2419397|55|CP026649|CRISPRCasFinder matches to NZ_CP033045 (Bacillus foraminis strain Bac44 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.8

cgacaacagcttggaaggctgtggttttaccactaaactacacccgcagcaaagg	CRISPR spacer
catcatcagcttggaaggctgaggttttaccactaaactacacccgcatggttaa	Protospacer
*. ** *************** **************************  .  ..

55. spacer 12.38|2907827|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP028971 (Aminobacter sp. MSH1 plasmid pUSP3, complete sequence) position: , mismatch: 11, identity: 0.676

--------ccagggtaaagacgaagtgacgtccaccctggat	CRISPR spacer
cattctgttc--------gacgaagtgacgtccgccctcgat	Protospacer
        .*        ***************.**** ***

56. spacer 12.46|2908356|34|CP026649|CRT,PILER-CR,CRISPRCasFinder matches to KC821606 (Cellulophaga phage phi12:2, complete genome) position: , mismatch: 11, identity: 0.676

acaacgccatttttgcggttgttccgcttcccat	CRISPR spacer
atccgcttccttttgtgcttgttccgcttcccat	Protospacer
*.    .. .*****.* ****************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

271013 : 339096

Bacillus_phage(30.0%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVD54911.1\|271013_272189_-\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	3.6e-84	42.6
AVD54912.1\|273245_275480_+	ribonucleoside-diphosphate reductase subunit alpha	A0A0Y0AS84	Bacillus_phage	1.0e-260	61.0
AVD54913.1\|275464_275947_+	flavodoxin	A0A060AL80	Listeria_phage	6.2e-14	36.9
AVD54914.1\|275891_276935_+	ribonucleotide-diphosphate reductase subunit beta	A0A059T7I4	Listeria_phage	5.8e-110	56.9
AVD54915.1\|277257_277872_-	hypothetical protein	NA	NA	NA	NA
AVD54916.1\|277868_278954_-	glycosyl transferase family 2	NA	NA	NA	NA
AVD54917.1\|279222_280152_+\|transposase	transposase	NA	NA	NA	NA
AVD54918.1\|280153_280390_+	hypothetical protein	NA	NA	NA	NA
AVD54919.1\|280386_280650_+	hypothetical protein	NA	NA	NA	NA
AVD54920.1\|280782_281280_+	thioesterase	NA	NA	NA	NA
AVD54921.1\|281336_282353_+	EamA family transporter	NA	NA	NA	NA
AVD57779.1\|282366_282681_-	QacE family quaternary ammonium compound efflux SMR transporter	NA	NA	NA	NA
AVD57780.1\|282680_283022_-	QacE family quaternary ammonium compound efflux SMR transporter	NA	NA	NA	NA
AVD54922.1\|283115_283898_-	hypothetical protein	NA	NA	NA	NA
AVD54923.1\|284037_285063_-	iron ABC transporter permease	NA	NA	NA	NA
AVD54924.1\|285062_286109_-	iron ABC transporter permease	NA	NA	NA	NA
AVD54925.1\|286265_287228_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AVD54926.1\|287250_287475_+	hypothetical protein	NA	NA	NA	NA
AVD54927.1\|287556_288372_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.2e-17	28.2
AVD54928.1\|288409_289441_+	thioredoxin reductase	G3MA85	Bacillus_virus	2.9e-21	26.6
AVD54929.1\|289580_290219_-	hypothetical protein	NA	NA	NA	NA
AVD57781.1\|290647_291268_+	membrane-spanning protein	NA	NA	NA	NA
AVD54930.1\|291260_291848_+	hypothetical protein	NA	NA	NA	NA
AVD54931.1\|291936_292140_-	hypothetical protein	NA	NA	NA	NA
AVD54932.1\|292232_292952_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
AVD54933.1\|293150_294170_+	STAS domain-containing protein	NA	NA	NA	NA
AVD54934.1\|294357_295602_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
AVD54935.1\|295579_296353_+	gluconate 5-dehydrogenase	NA	NA	NA	NA
AVD54936.1\|298121_298685_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AVD54937.1\|298837_299026_+	hypothetical protein	NA	NA	NA	NA
AVD54938.1\|299411_299816_+	acyl-CoA thioesterase	NA	NA	NA	NA
AVD54939.1\|299858_300917_+	phosphotransferase family protein	NA	NA	NA	NA
AVD54940.1\|301300_302719_+	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
AVD54941.1\|305762_307166_-	pectate lyase	D6R401	Bacillus_phage	1.3e-99	47.8
AVD54942.1\|307335_307641_+	hypothetical protein	NA	NA	NA	NA
AVD54943.1\|308162_308888_+	phosphoadenylyl-sulfate reductase	M4W6M9	Bacillus_phage	5.3e-09	24.5
AVD54944.1\|309111_309291_+	hypothetical protein	NA	NA	NA	NA
AVD54945.1\|309287_310046_+	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
AVD54946.1\|310052_310793_+	sirohydrochlorin chelatase	NA	NA	NA	NA
AVD54947.1\|310835_311060_+	hypothetical protein	NA	NA	NA	NA
AVD54948.1\|311079_311706_+	siroheme synthase	NA	NA	NA	NA
AVD54949.1\|311838_312369_+	YbaK/EbsC family protein	NA	NA	NA	NA
AVD54950.1\|313977_315081_-	glycerol dehydrogenase	NA	NA	NA	NA
AVD54951.1\|315313_316906_+	AMP-dependent synthetase	A0A2H4PQM9	Staphylococcus_phage	1.3e-44	27.5
AVD57782.1\|317553_318594_+	GGDEF domain-containing protein	NA	NA	NA	NA
AVD54952.1\|318885_319110_-	hypothetical protein	NA	NA	NA	NA
AVD54953.1\|319232_320162_-	EamA family transporter	NA	NA	NA	NA
AVD54954.1\|320383_321277_+	NERD nuclease	NA	NA	NA	NA
AVD54955.1\|321994_322936_-	cation transporter	NA	NA	NA	NA
AVD54956.1\|323232_325068_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	Q84421	Paramecium_bursaria_Chlorella_virus	4.9e-104	38.1
AVD57783.1\|326812_327754_+	mevalonate kinase	NA	NA	NA	NA
AVD54957.1\|327801_328038_-	hypothetical protein	NA	NA	NA	NA
AVD54958.1\|328096_329077_+	diphosphomevalonate decarboxylase	NA	NA	NA	NA
AVD54959.1\|329073_329307_-	hypothetical protein	NA	NA	NA	NA
AVD54960.1\|330669_331314_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
AVD54961.1\|331675_333070_-\|transposase	IS4 family transposase	NA	NA	NA	NA
AVD54962.1\|333241_334270_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
AVD54963.1\|334326_334896_+	dihydrofolate reductase	NA	NA	NA	NA
AVD54964.1\|335486_336797_+\|transposase	transposase	NA	NA	NA	NA
AVD54965.1\|337758_339096_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_2

974650 : 980835

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVD55451.1\|974650_975598_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	7.0e-86	52.8
AVD55452.1\|976387_976846_+	8-oxo-dGTP diphosphatase	K4F7D9	Cronobacter_phage	6.9e-07	33.3
AVD55453.1\|976882_977773_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	4.3e-05	29.8
AVD55454.1\|977769_978750_+	YvcK family protein	A1IMD5	Streptococcus_phage	1.2e-67	44.6
AVD55455.1\|978830_979784_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	9.2e-54	39.1
AVD55456.1\|979894_980164_+	HPr family phosphocarrier protein	NA	NA	NA	NA
AVD55457.1\|980250_980835_-	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.3e-53	56.0

DBSCAN-SWA_3

1583529 : 1591960

Ostreococcus_lucimarinus_virus(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVD56024.1\|1583529_1585200_-	AarF/ABC1/UbiB kinase family protein	A0A0P0CRP3	Ostreococcus_lucimarinus_virus	9.2e-49	34.5
AVD56025.1\|1585265_1585562_-	hypothetical protein	NA	NA	NA	NA
AVD56026.1\|1585658_1586189_-	peptide-methionine (S)-S-oxide reductase	NA	NA	NA	NA
AVD56027.1\|1586436_1586688_+	hypothetical protein	NA	NA	NA	NA
AVD56028.1\|1586836_1587040_-	cold-shock protein	Q9AZD3	Lactococcus_phage	5.9e-19	66.2
AVD56029.1\|1587212_1588262_-\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	2.0e-25	27.8
AVD56030.1\|1588577_1589225_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	8.5e-59	53.0
AVD56031.1\|1589387_1590611_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	3.7e-79	46.5
AVD56032.1\|1591021_1591960_+	NAD(P)/FAD-dependent oxidoreductase	G3MA85	Bacillus_virus	1.4e-30	34.3

DBSCAN-SWA_4

1770313 : 1834964

Bacillus_phage(26.67%)

protease,terminase,capsid,tRNA,integrase,transposase,tail,portal,holin,head

attL 1772306:1772365|attR 1808184:1808282

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVD56198.1\|1770313_1770967_-	resolvase	D7RWL2	Brochothrix_phage	3.2e-05	25.3
AVD56199.1\|1770963_1771302_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
AVD56200.1\|1771508_1772129_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	2.5e-15	62.3
1772306:1772365	attL	NA	NA	NA	NA
AVD56201.1\|1772578_1773295_+	hypothetical protein	NA	NA	NA	NA
AVD56202.1\|1773399_1774239_-	LysM peptidoglycan-binding domain-containing protein	Q5ILA1	Bacillus_phage	4.8e-14	29.8
AVD57844.1\|1774293_1774527_-\|holin	phage holin	M4ZR48	Bacillus_phage	3.9e-22	67.5
AVD57845.1\|1774544_1774802_-	hypothetical protein	NA	NA	NA	NA
AVD56203.1\|1774935_1775190_-	hypothetical protein	A0A2H4J8H2	uncultured_Caudovirales_phage	5.5e-06	41.5
AVD56204.1\|1775430_1775721_-	hypothetical protein	NA	NA	NA	NA
AVD56205.1\|1775736_1776465_-	hypothetical protein	A0A2P0ZL22	Lactobacillus_phage	4.8e-34	38.2
AVD56206.1\|1776474_1777944_-	hypothetical protein	A0A0U4JVA9	Exiguobacterium_phage	4.5e-15	43.4
AVD56207.1\|1777943_1779350_-	hypothetical protein	Q9T1A5	Listeria_phage	2.9e-72	41.1
AVD56208.1\|1779358_1780183_-	hypothetical protein	A8ATA8	Listeria_phage	4.7e-30	34.3
AVD56209.1\|1780191_1784385_-	hypothetical protein	A0A059T5F4	Listeria_phage	1.2e-89	33.0
AVD56210.1\|1784666_1784993_-	hypothetical protein	NA	NA	NA	NA
AVD56211.1\|1785046_1785655_-\|tail	phage tail protein	NA	NA	NA	NA
AVD56212.1\|1785667_1786054_-	hypothetical protein	NA	NA	NA	NA
AVD56213.1\|1786050_1786485_-\|head,tail	head-tail adaptor protein	A0A1B1P9Z7	Enterococcus_phage	4.9e-10	33.3
AVD56214.1\|1786481_1786814_-\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
AVD56215.1\|1786816_1787098_-\|head,tail	phage gp6-like head-tail connector protein	A6M953	Geobacillus_virus	5.9e-25	60.9
AVD56216.1\|1787111_1788275_-\|capsid	phage major capsid protein	A0A0A7S154	Clostridium_phage	3.9e-78	43.4
AVD56217.1\|1788274_1788994_-\|protease	Clp protease ClpP	A0A2I7SCY8	Paenibacillus_phage	2.8e-55	53.6
AVD56218.1\|1788980_1790267_-\|portal	phage portal protein	Q0SPK2	Clostridium_phage	5.7e-131	54.3
AVD56219.1\|1790285_1791854_-\|terminase	terminase large subunit	A0A2I7SBY8	Paenibacillus_phage	7.6e-247	74.7
AVD56220.1\|1791843_1792380_-	hypothetical protein	A0A2I7SBY3	Paenibacillus_phage	1.9e-16	34.3
AVD56221.1\|1792487_1792859_-	HNH endonuclease	A0A1U7Q1S7	Geobacillus_virus	1.9e-31	52.3
AVD56222.1\|1792864_1793083_-	hypothetical protein	NA	NA	NA	NA
AVD56223.1\|1793406_1793706_-	hypothetical protein	NA	NA	NA	NA
AVD56224.1\|1793867_1794410_-\|integrase	site-specific integrase	D2XR58	Bacillus_phage	8.7e-57	60.6
AVD56225.1\|1794406_1794862_-	ArpU family transcriptional regulator	S6AVV9	Thermus_phage	1.5e-38	54.9
AVD56226.1\|1794964_1795651_-	hypothetical protein	A0A2P1JTZ2	Anoxybacillus_phage	4.8e-36	39.1
AVD56227.1\|1795713_1795953_-	hypothetical protein	NA	NA	NA	NA
AVD56228.1\|1795970_1796171_-	hypothetical protein	NA	NA	NA	NA
AVD56229.1\|1796176_1796479_-	hypothetical protein	NA	NA	NA	NA
AVD56230.1\|1796493_1796808_-	hypothetical protein	NA	NA	NA	NA
AVD56231.1\|1796944_1797133_-	hypothetical protein	NA	NA	NA	NA
AVD56232.1\|1797265_1797475_-\|terminase	terminase	NA	NA	NA	NA
AVD56233.1\|1797736_1798732_-	replication protein	A0A0U4JX08	Bacillus_phage	1.3e-37	59.8
AVD56234.1\|1798744_1799044_-	hypothetical protein	NA	NA	NA	NA
AVD56235.1\|1799272_1799464_-	hypothetical protein	NA	NA	NA	NA
AVD56236.1\|1799550_1799832_-	hypothetical protein	NA	NA	NA	NA
AVD57846.1\|1799844_1800114_-	group-specific protein	A0A1B1P7U4	Bacillus_phage	3.5e-27	62.8
AVD56237.1\|1800138_1800660_-	XRE family transcriptional regulator	NA	NA	NA	NA
AVD56238.1\|1800948_1801176_-	XRE family transcriptional regulator	NA	NA	NA	NA
AVD56239.1\|1801321_1801741_+	XRE family transcriptional regulator	A0A1B1P888	Bacillus_phage	3.0e-09	51.7
AVD56240.1\|1801869_1802787_+	NAD-dependent DNA ligase	NA	NA	NA	NA
AVD56241.1\|1802816_1803779_+	hypothetical protein	A0A0A8WJ41	Clostridium_phage	1.9e-30	39.2
AVD56242.1\|1803924_1805439_+	hypothetical protein	NA	NA	NA	NA
AVD56243.1\|1805469_1806333_+	DNA methyltransferase	M4SNK2	Cyanophage	1.0e-06	24.5
AVD56244.1\|1806431_1806941_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
AVD56245.1\|1806977_1808117_+\|integrase	site-specific integrase	A0A0S2SXP1	Bacillus_phage	2.0e-71	71.9
AVD56246.1\|1808225_1809563_-	type I glutamate--ammonia ligase	NA	NA	NA	NA
1808184:1808282	attR	NA	NA	NA	NA
AVD56247.1\|1809632_1810022_-	MerR family transcriptional regulator	NA	NA	NA	NA
AVD56248.1\|1810114_1813714_-	dynamin	NA	NA	NA	NA
AVD56249.1\|1813879_1814083_+	methionine aminopeptidase	NA	NA	NA	NA
AVD56250.1\|1815092_1816406_-	purine permease	NA	NA	NA	NA
AVD56251.1\|1816402_1816990_-	xanthine phosphoribosyltransferase	NA	NA	NA	NA
AVD56252.1\|1817318_1817522_+	hypothetical protein	NA	NA	NA	NA
AVD56253.1\|1817536_1819057_-	carboxypeptidase M32	NA	NA	NA	NA
AVD56254.1\|1819138_1820284_-	RNA methyltransferase	NA	NA	NA	NA
AVD56255.1\|1821013_1821316_-	cell division regulator GpsB	NA	NA	NA	NA
AVD56256.1\|1821396_1821948_-	DUF1273 domain-containing protein	NA	NA	NA	NA
AVD56257.1\|1822017_1822269_-	hypothetical protein	NA	NA	NA	NA
AVD56258.1\|1822607_1823906_-	hypothetical protein	NA	NA	NA	NA
AVD56259.1\|1823886_1826187_-	DUF1998 domain-containing protein	A0A1B1IUF6	uncultured_Mediterranean_phage	1.5e-09	32.5
AVD56260.1\|1826336_1826780_+	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
AVD56261.1\|1827410_1827773_-	DUF1798 domain-containing protein	NA	NA	NA	NA
AVD56262.1\|1827840_1828080_-	hypothetical protein	NA	NA	NA	NA
AVD56263.1\|1828108_1828345_-\|transposase	transposase	NA	NA	NA	NA
AVD56264.1\|1828636_1829242_+	Holliday junction resolvase RecU	NA	NA	NA	NA
AVD56265.1\|1829334_1832070_+	penicillin-binding protein	NA	NA	NA	NA
AVD56266.1\|1832157_1832817_-	endonuclease III	NA	NA	NA	NA
AVD56267.1\|1832864_1833560_-	DnaD domain protein	A0A0N7AE27	Bacillus_phage	2.3e-25	48.7
AVD57847.1\|1833671_1834964_-\|tRNA	asparagine--tRNA ligase	M1PB22	Moumouvirus	2.7e-56	30.8

DBSCAN-SWA_5

1843167 : 1886769

Bacillus_phage(22.22%)

tRNA,protease,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVD56275.1\|1843167_1844370_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	1.7e-41	46.6
AVD56276.1\|1844323_1845508_-	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
AVD56277.1\|1845504_1846212_-	bacillithiol biosynthesis deacetylase BshB1	NA	NA	NA	NA
AVD56278.1\|1846230_1847031_-	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
AVD56279.1\|1847037_1847382_-	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
AVD56280.1\|1847533_1848397_+	YitT family protein	M1Q1P6	Streptococcus_phage	4.7e-73	44.8
AVD56281.1\|1848423_1848906_-	QueT transporter family protein	NA	NA	NA	NA
AVD56282.1\|1849059_1849746_-\|protease	Zn-dependent protease	NA	NA	NA	NA
AVD56283.1\|1849809_1850601_-	sporulation protein YpjB	NA	NA	NA	NA
AVD56284.1\|1850715_1851312_-	DUF1405 domain-containing protein	NA	NA	NA	NA
AVD56285.1\|1851399_1852164_-	cytochrome C oxidase Cbb3	NA	NA	NA	NA
AVD56286.1\|1852202_1852877_-	cytochrome b/b6	NA	NA	NA	NA
AVD56287.1\|1852887_1853400_-	menaquinol-cytochrome C reductase	NA	NA	NA	NA
AVD56288.1\|1853562_1854024_-	DUF2487 domain-containing protein	NA	NA	NA	NA
AVD56289.1\|1854069_1854615_-	hypothetical protein	G3MAV7	Bacillus_virus	7.6e-45	53.6
AVD56290.1\|1854750_1856016_-	tetratricopeptide repeat protein	NA	NA	NA	NA
AVD56291.1\|1856237_1856516_+	hypothetical protein	NA	NA	NA	NA
AVD56292.1\|1856474_1857758_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
AVD56293.1\|1857773_1858874_-	prephenate dehydrogenase	NA	NA	NA	NA
AVD56294.1\|1858937_1860032_-	histidinol-phosphate transaminase	A0A0H3TLT9	Faustovirus	2.5e-26	27.9
AVD56295.1\|1860123_1860486_-	chorismate mutase	NA	NA	NA	NA
AVD56296.1\|1860482_1861565_-	3-dehydroquinate synthase	NA	NA	NA	NA
AVD56297.1\|1861565_1862735_-	chorismate synthase	A0A291AU41	Pandoravirus	4.6e-47	38.0
AVD56298.1\|1862817_1863606_-	chemotaxis protein CheR	NA	NA	NA	NA
AVD56299.1\|1863709_1864156_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.7e-26	42.7
AVD56300.1\|1864307_1865270_-	heptaprenyl diphosphate synthase component II	A0A1V0SE37	Indivirus	6.1e-05	23.0
AVD56301.1\|1865288_1865993_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
AVD56302.1\|1865995_1866805_-	heptaprenyl diphosphate synthase	NA	NA	NA	NA
AVD56303.1\|1866901_1867132_-	trp RNA-binding attenuation protein MtrB	NA	NA	NA	NA
AVD56304.1\|1867175_1867379_-	hypothetical protein	NA	NA	NA	NA
AVD56305.1\|1867385_1867658_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	2.0e-30	77.8
AVD56306.1\|1867947_1869426_-	stage IV sporulation protein A	NA	NA	NA	NA
AVD56307.1\|1869669_1870389_-	hypothetical protein	NA	NA	NA	NA
AVD56308.1\|1870407_1870614_-	DUF2768 domain-containing protein	NA	NA	NA	NA
AVD56309.1\|1870853_1871894_-	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
AVD56310.1\|1871914_1873225_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
AVD56311.1\|1873313_1873910_-	hypothetical protein	NA	NA	NA	NA
AVD56312.1\|1874010_1874139_+	YpzI family protein	NA	NA	NA	NA
AVD56313.1\|1874233_1875370_-	30S ribosomal protein S1	NA	NA	NA	NA
AVD56314.1\|1875482_1876187_-	(d)CMP kinase	NA	NA	NA	NA
AVD56315.1\|1876308_1876953_-	pilus assembly protein PilZ	NA	NA	NA	NA
AVD56316.1\|1877074_1878424_-	germination protein YpeB	NA	NA	NA	NA
AVD56317.1\|1878439_1879234_-	spore cortex-lytic enzyme	A0A0E3XAL9	Bacillus_phage	8.3e-24	46.8
AVD56318.1\|1879345_1880026_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
AVD57848.1\|1880133_1881117_-	YpdA family putative bacillithiol disulfide reductase	NA	NA	NA	NA
AVD56319.1\|1881274_1882552_-	Glu/Leu/Phe/Val dehydrogenase	NA	NA	NA	NA
AVD56320.1\|1882649_1883195_-	NDP-hexose 2,3-dehydratase	NA	NA	NA	NA
AVD56321.1\|1883254_1884034_-	metallophosphoesterase	NA	NA	NA	NA
AVD56322.1\|1884210_1884438_+\|coat	spore coat associated protein CotJA	NA	NA	NA	NA
AVD56323.1\|1884434_1884695_+\|coat	spore coat protein CotJB	NA	NA	NA	NA
AVD56324.1\|1884718_1885288_+\|coat	spore coat protein CotJC	NA	NA	NA	NA
AVD56325.1\|1885352_1885799_-	DUF2663 domain-containing protein	NA	NA	NA	NA
AVD56326.1\|1885926_1886166_-	hypothetical protein	NA	NA	NA	NA
AVD56327.1\|1886190_1886769_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_6

2138600 : 2198257

Moraxella_phage(25.0%)

tRNA,transposase,protease,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVD56582.1\|2138600_2139629_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
AVD56583.1\|2139664_2139871_-	DUF2905 domain-containing protein	NA	NA	NA	NA
AVD56584.1\|2139867_2140866_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	2.1e-08	25.6
AVD56585.1\|2140882_2141485_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
AVD56586.1\|2141501_2141681_-	hypothetical protein	NA	NA	NA	NA
AVD56587.1\|2141765_2141981_-	hypothetical protein	NA	NA	NA	NA
AVD56588.1\|2141983_2142703_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
AVD56589.1\|2142815_2143784_-	aminoglycoside phosphotransferase family protein	NA	NA	NA	NA
AVD56590.1\|2143783_2145055_-\|coat	spore coat protein	S6BFI4	Thermus_phage	6.2e-05	55.6
AVD56591.1\|2145241_2145799_+	transcription repressor NadR	NA	NA	NA	NA
AVD56592.1\|2145925_2146771_-	prephenate dehydratase	NA	NA	NA	NA
AVD56593.1\|2146796_2147249_-	ACT domain-containing protein	NA	NA	NA	NA
AVD56594.1\|2147297_2148590_-	GTPase ObgE	NA	NA	NA	NA
AVD56595.1\|2148624_2149161_-	sporulation protein	NA	NA	NA	NA
AVD57859.1\|2149366_2149660_-	50S ribosomal protein L27	NA	NA	NA	NA
AVD56596.1\|2149669_2149999_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
AVD56597.1\|2150011_2150320_-	50S ribosomal protein L21	NA	NA	NA	NA
AVD56598.1\|2150462_2151941_-	ribonuclease E/G	NA	NA	NA	NA
AVD56599.1\|2151992_2152859_-	stage IV sporulation protein FB	NA	NA	NA	NA
AVD56600.1\|2152851_2153604_-	M23 family peptidase	NA	NA	NA	NA
AVD56601.1\|2153730_2154540_-	septum site-determining protein MinD	NA	NA	NA	NA
AVD56602.1\|2154532_2155225_-	septum site-determining protein MinC	NA	NA	NA	NA
AVD56603.1\|2155449_2155968_-	rod shape-determining protein MreD	NA	NA	NA	NA
AVD56604.1\|2155967_2156834_-	rod shape-determining protein MreC	NA	NA	NA	NA
AVD56605.1\|2156940_2157957_-	rod shape-determining protein	NA	NA	NA	NA
AVD56606.1\|2158130_2158814_-	hypothetical protein	NA	NA	NA	NA
AVD56607.1\|2158798_2158993_-	hypothetical protein	NA	NA	NA	NA
AVD56608.1\|2159225_2160449_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	1.1e-78	46.2
AVD56609.1\|2160791_2161775_-	hypothetical protein	NA	NA	NA	NA
AVD56610.1\|2161893_2162655_-	prepilin peptidase	NA	NA	NA	NA
AVD56611.1\|2162760_2163465_-	pilus assembly protein PilO	NA	NA	NA	NA
AVD56612.1\|2163461_2164340_-	fimbrial protein	NA	NA	NA	NA
AVD56613.1\|2164340_2165339_-	pilus assembly protein PilM	NA	NA	NA	NA
AVD56614.1\|2165441_2165876_-	pilus assembly protein	NA	NA	NA	NA
AVD56615.1\|2165958_2167164_-	type II secretion system F family protein	NA	NA	NA	NA
AVD56616.1\|2167150_2168203_-	type IV pili twitching motility protein PilT	NA	NA	NA	NA
AVD56617.1\|2168212_2169874_-	type II secretion system protein GspE	NA	NA	NA	NA
AVD56618.1\|2169919_2171374_-	hypothetical protein	NA	NA	NA	NA
AVD56619.1\|2171390_2172119_-	photosystem reaction center subunit H	NA	NA	NA	NA
AVD56620.1\|2172145_2173918_-	hypothetical protein	NA	NA	NA	NA
AVD57860.1\|2174045_2175707_-	hypothetical protein	NA	NA	NA	NA
AVD56621.1\|2175706_2176216_-	pilin	NA	NA	NA	NA
AVD56622.1\|2176212_2176632_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
AVD56623.1\|2176750_2178073_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
AVD56624.1\|2178135_2180781_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	3.4e-162	43.7
AVD56625.1\|2181207_2181399_+	hypothetical protein	NA	NA	NA	NA
AVD56626.1\|2181415_2182600_-\|coat	spore coat protein YsxE	NA	NA	NA	NA
AVD56627.1\|2182630_2184448_-	stage VI sporulation protein D	NA	NA	NA	NA
AVD56628.1\|2184833_2186123_-	glutamate-1-semialdehyde-2,1-aminomutase	A0A1V0SKB7	Klosneuvirus	4.4e-06	27.6
AVD56629.1\|2186138_2187116_-	porphobilinogen synthase	NA	NA	NA	NA
AVD56630.1\|2187148_2187367_+	hypothetical protein	NA	NA	NA	NA
AVD56631.1\|2187352_2188141_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
AVD56632.1\|2188137_2189070_-	hydroxymethylbilane synthase	NA	NA	NA	NA
AVD56633.1\|2189082_2189907_-	cytochrome C assembly protein	NA	NA	NA	NA
AVD56634.1\|2189922_2191254_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
AVD56635.1\|2191439_2191934_+	hypothetical protein	NA	NA	NA	NA
AVD56636.1\|2192110_2192695_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
AVD56637.1\|2192691_2195016_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	4.8e-181	44.5
AVD56638.1\|2195059_2196697_-\|protease	ATP-dependent protease LonB	A0A0R6PGP8	Moraxella_phage	2.9e-15	36.4
AVD56639.1\|2196988_2198257_-\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	5.4e-150	67.4

DBSCAN-SWA_7

2400737 : 2472934

Staphylococcus_phage(23.08%)

transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVD56817.1\|2400737_2402153_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
AVD56818.1\|2404141_2404912_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.3e-37	38.4
AVD56819.1\|2404898_2405705_+	ABC transporter permease	NA	NA	NA	NA
AVD56820.1\|2406236_2406701_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.4e-25	37.7
AVD56821.1\|2406869_2407118_+	DUF1836 domain-containing protein	NA	NA	NA	NA
AVD56822.1\|2407190_2407640_-	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	1.5e-38	52.4
AVD56823.1\|2407756_2407993_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.1e-19	63.8
AVD56824.1\|2408084_2408213_+	DUF4021 domain-containing protein	NA	NA	NA	NA
AVD56825.1\|2408332_2409223_+	adhesin	NA	NA	NA	NA
AVD56826.1\|2409285_2409444_+	DUF1540 domain-containing protein	NA	NA	NA	NA
AVD56827.1\|2409814_2410918_-	o-succinylbenzoate synthase	NA	NA	NA	NA
AVD56828.1\|2412945_2413764_-	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
AVD56829.1\|2413804_2414608_-	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
AVD56830.1\|2414604_2416350_-	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
AVD57866.1\|2416351_2417686_-	isochorismate synthase	NA	NA	NA	NA
AVD56831.1\|2417951_2418875_+	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
AVD56832.1\|2426759_2426945_-	hypothetical protein	NA	NA	NA	NA
AVD56833.1\|2427234_2428398_+	glycosyltransferase family 1 protein	NA	NA	NA	NA
AVD56834.1\|2428725_2429376_-\|bacteriocin	bacteriocin ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-20	30.7
AVD56835.1\|2429377_2431567_-	hypothetical protein	NA	NA	NA	NA
AVD56836.1\|2431864_2432044_-	hypothetical protein	NA	NA	NA	NA
AVD56837.1\|2432046_2432292_-	hypothetical protein	NA	NA	NA	NA
AVD56838.1\|2432344_2433250_-	EamA/RhaT family transporter	NA	NA	NA	NA
AVD56839.1\|2433340_2434030_+	MgtC/SapB family protein	G3MA03	Bacillus_virus	3.0e-14	35.7
AVD56840.1\|2434165_2435290_-	DUF1646 domain-containing protein	NA	NA	NA	NA
AVD56841.1\|2435799_2436186_-	MFS transporter	NA	NA	NA	NA
AVD56842.1\|2436489_2438901_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	4.8e-115	38.0
AVD56843.1\|2438994_2439201_-	copper resistance protein CopZ	NA	NA	NA	NA
AVD56844.1\|2439215_2439560_-	CsoR family transcriptional regulator	NA	NA	NA	NA
AVD56845.1\|2439839_2441255_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
AVD56846.1\|2442048_2442495_+	XRE family transcriptional regulator	A0A0A7RUJ5	Clostridium_phage	3.4e-06	51.8
AVD56847.1\|2442770_2444075_+\|transposase	IS1380-like element ISBco2 family transposase	NA	NA	NA	NA
AVD56848.1\|2444229_2444502_+	cytosolic protein	NA	NA	NA	NA
AVD56849.1\|2444602_2445013_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
AVD56850.1\|2445119_2445539_+	alkylhydroperoxidase	NA	NA	NA	NA
AVD56851.1\|2445566_2445749_+	hypothetical protein	NA	NA	NA	NA
AVD56852.1\|2445819_2447007_+	amidohydrolase	NA	NA	NA	NA
AVD56853.1\|2447067_2447262_+	DUF3311 domain-containing protein	NA	NA	NA	NA
AVD56854.1\|2447258_2448728_+	sodium:solute symporter	NA	NA	NA	NA
AVD56855.1\|2449399_2449618_-	hypothetical protein	NA	NA	NA	NA
AVD56856.1\|2449834_2450272_+	hypothetical protein	NA	NA	NA	NA
AVD56857.1\|2450302_2451700_+	sensor histidine kinase	W8CYF6	Bacillus_phage	9.8e-36	34.8
AVD56858.1\|2451674_2452349_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	3.8e-38	35.6
AVD56859.1\|2452420_2452975_-	DUF1541 domain-containing protein	NA	NA	NA	NA
AVD56860.1\|2453155_2453767_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
AVD56861.1\|2453780_2454434_-	hypothetical protein	NA	NA	NA	NA
AVD56862.1\|2454430_2455366_-	polysaccharide deacetylase	A0A1V0SLN0	Klosneuvirus	3.7e-07	25.7
AVD56863.1\|2458943_2459240_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	4.2e-13	39.6
AVD56864.1\|2459321_2459582_-	metal-sensitive transcriptional regulator	NA	NA	NA	NA
AVD56865.1\|2460163_2460952_+	endonuclease	A0A1P8CWK6	Bacillus_phage	1.4e-60	65.2
AVD56866.1\|2461054_2461564_-	PTS glucose transporter subunit IIA	NA	NA	NA	NA
AVD56867.1\|2461921_2463337_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
AVD56868.1\|2463792_2465394_-	ATPase	NA	NA	NA	NA
AVD56869.1\|2465411_2466818_-	sugar porter family MFS transporter	NA	NA	NA	NA
AVD56870.1\|2467302_2468001_+	L-ribulose-5-phosphate 4-epimerase AraD	NA	NA	NA	NA
AVD57867.1\|2468032_2469457_+	L-arabinose isomerase	NA	NA	NA	NA
AVD56871.1\|2469629_2470769_-	GntR family transcriptional regulator	NA	NA	NA	NA
AVD56872.1\|2471623_2472934_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_8

2642917 : 2695497

Planktothrix_phage(20.0%)

tRNA,transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVD57015.1\|2642917_2644141_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	3.7e-79	46.5
AVD57016.1\|2644507_2646403_-	protein prkA	A0MN77	Thermus_phage	1.1e-103	37.3
AVD57017.1\|2646578_2646764_+	hypothetical protein	NA	NA	NA	NA
AVD57018.1\|2646802_2647039_+	hypothetical protein	NA	NA	NA	NA
AVD57019.1\|2647056_2647530_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
AVD57020.1\|2647565_2648447_-	hypothetical protein	NA	NA	NA	NA
AVD57021.1\|2648766_2649897_-\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
AVD57022.1\|2650272_2650896_+	hypothetical protein	NA	NA	NA	NA
AVD57023.1\|2650966_2651248_+	hypothetical protein	NA	NA	NA	NA
AVD57024.1\|2651224_2652154_-	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
AVD57025.1\|2652326_2652791_+	rubrerythrin family protein	NA	NA	NA	NA
AVD57026.1\|2652799_2653657_-	proline iminopeptidase	A0A2K9KZN8	Tupanvirus	1.9e-05	30.9
AVD57027.1\|2653807_2654605_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
AVD57028.1\|2654591_2655284_+	amino acid ABC transporter permease	NA	NA	NA	NA
AVD57029.1\|2655296_2656034_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-31	39.6
AVD57030.1\|2656096_2656933_-	formate/nitrite transporter family protein	NA	NA	NA	NA
AVD57031.1\|2657292_2658453_-	L-threonine dehydrogenase	NA	NA	NA	NA
AVD57032.1\|2658831_2661096_+	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	6.6e-183	45.2
AVD57033.1\|2661185_2661923_+	pyruvate formate lyase-activating protein	NA	NA	NA	NA
AVD57034.1\|2662183_2662741_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
AVD57035.1\|2662759_2663293_-	hypothetical protein	NA	NA	NA	NA
AVD57036.1\|2663411_2664392_-	ABC transporter permease	NA	NA	NA	NA
AVD57037.1\|2664388_2665300_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.5e-37	38.4
AVD57038.1\|2665296_2666100_-	GDSL family lipase	NA	NA	NA	NA
AVD57039.1\|2666534_2666765_-	hypothetical protein	NA	NA	NA	NA
AVD57040.1\|2667027_2668713_+\|transposase	IS4 family transposase	NA	NA	NA	NA
AVD57041.1\|2669354_2670335_+	hypothetical protein	NA	NA	NA	NA
AVD57042.1\|2670741_2671779_-	hypothetical protein	NA	NA	NA	NA
AVD57043.1\|2672210_2672909_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	3.1e-30	33.0
AVD57044.1\|2674445_2675078_-	hypothetical protein	NA	NA	NA	NA
AVD57045.1\|2675370_2675898_+	folate family ECF transporter S component	NA	NA	NA	NA
AVD57046.1\|2677760_2678483_+	GntR family transcriptional regulator	NA	NA	NA	NA
AVD57047.1\|2678615_2680127_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.2e-76	40.2
AVD57874.1\|2680152_2681280_+	FAD-binding oxidoreductase	NA	NA	NA	NA
AVD57048.1\|2681652_2681844_+	hypothetical protein	NA	NA	NA	NA
AVD57049.1\|2681833_2682439_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	1.5e-09	30.3
AVD57050.1\|2682454_2683975_-\|transposase	IS5-like element ISBco3 family transposase	NA	NA	NA	NA
AVD57051.1\|2684247_2684904_+	hypothetical protein	NA	NA	NA	NA
AVD57052.1\|2686710_2687175_-	MarR family transcriptional regulator	NA	NA	NA	NA
AVD57053.1\|2687320_2688754_+\|transposase	transposase	NA	NA	NA	NA
AVD57054.1\|2689130_2689946_-	cytochrome c oxidase assembly protein	NA	NA	NA	NA
AVD57875.1\|2689954_2690437_-	DUF2243 domain-containing protein	NA	NA	NA	NA
AVD57055.1\|2690790_2691429_-\|bacteriocin	bacteriocin ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.8e-24	38.1
AVD57056.1\|2691435_2693682_-	DUF1430 domain-containing protein	NA	NA	NA	NA
AVD57057.1\|2693790_2693925_-	hypothetical protein	NA	NA	NA	NA
AVD57058.1\|2694186_2695497_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_9

2957254 : 3110455

112

Streptococcus_phage(17.24%)

transposase,integrase

attL 3043523:3043541|attR 3110142:3110160

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVD57257.1\|2957254_2958478_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	1.1e-78	46.2
AVD57258.1\|2958926_2959112_-	type Z 30S ribosomal protein S14	NA	NA	NA	NA
AVD57259.1\|2959402_2959633_-	hypothetical protein	NA	NA	NA	NA
AVD57260.1\|2959951_2960515_-	pyridine nucleotide-disulfide oxidoreductase	NA	NA	NA	NA
AVD57261.1\|2960685_2961144_-	hypothetical protein	NA	NA	NA	NA
AVD57262.1\|2961246_2961693_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AVD57263.1\|2961841_2963359_-	carboxylase	NA	NA	NA	NA
AVD57264.1\|2963363_2964143_-	enoyl-CoA hydratase	NA	NA	NA	NA
AVD57265.1\|2964349_2964727_-	hypothetical protein	NA	NA	NA	NA
AVD57266.1\|2964737_2965646_-	hydroxymethylglutaryl-CoA lyase	A0A1V0SKU2	Klosneuvirus	3.5e-34	36.3
AVD57267.1\|2965672_2965882_-	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit	NA	NA	NA	NA
AVD57268.1\|2966176_2967532_-	biotin carboxylase	NA	NA	NA	NA
AVD57269.1\|2967753_2968896_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
AVD57270.1\|2969146_2971102_-	acetyl-coenzyme A synthetase	A0A2H4PQU7	Staphylococcus_phage	9.7e-82	39.4
AVD57271.1\|2971757_2973308_-	AMP-dependent synthetase	A0A2H4PQM9	Staphylococcus_phage	8.3e-28	28.5
AVD57272.1\|2973844_2975212_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
AVD57273.1\|2975930_2977142_-	ornithine--oxo-acid transaminase	A0A1V0SKB7	Klosneuvirus	2.0e-29	28.3
AVD57274.1\|2977304_2978651_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
AVD57890.1\|2978746_2980210_-	restriction endonuclease	NA	NA	NA	NA
AVD57275.1\|2980227_2981658_-	SAM-dependent methyltransferase	A0A220A2U4	Liberibacter_phage	1.0e-27	23.4
AVD57276.1\|2981795_2981975_-	hypothetical protein	NA	NA	NA	NA
AVD57277.1\|2982152_2985359_-	type I restriction-modification system endonuclease	Q5YA94	Bacillus_phage	3.2e-05	26.7
AVD57278.1\|2985408_2985645_-	hypothetical protein	NA	NA	NA	NA
AVD57279.1\|2985940_2987422_+	gamma-aminobutyrate permease	NA	NA	NA	NA
AVD57280.1\|2988601_2989255_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AVD57281.1\|2989268_2990492_-	ABC transporter	NA	NA	NA	NA
AVD57891.1\|2990488_2990593_-	histidine kinase	NA	NA	NA	NA
AVD57282.1\|2990791_2991517_-	glycosyl transferase family 2	A0A2H4PQG7	Staphylococcus_phage	2.3e-28	36.0
AVD57283.1\|2991744_2992161_+	hypothetical protein	NA	NA	NA	NA
AVD57284.1\|2992173_2992476_+	hypothetical protein	NA	NA	NA	NA
AVD57285.1\|2992493_2992763_+	hypothetical protein	NA	NA	NA	NA
AVD57286.1\|2998851_2999745_+	fructose bisphosphate aldolase	A0A0K0KVJ8	Prochlorococcus_phage	2.4e-11	29.0
AVD57287.1\|3000539_3001847_-\|transposase	IS1182-like element ISBco4 family transposase	NA	NA	NA	NA
AVD57288.1\|3001966_3003382_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
AVD57289.1\|3003891_3005385_+	histidine ammonia-lyase	A0A1V0S940	Catovirus	6.9e-104	42.3
AVD57290.1\|3005493_3006285_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.1e-39	42.2
AVD57892.1\|3006304_3007084_-	ABC transporter permease	G3M9Y4	Bacillus_virus	8.1e-32	33.1
AVD57291.1\|3007182_3008457_-	imidazolonepropionase	NA	NA	NA	NA
AVD57893.1\|3008475_3010440_-	urocanate hydratase	NA	NA	NA	NA
AVD57292.1\|3010524_3011538_-	aliphatic sulfonate ABC transporter substrate-binding protein	G3M9Z0	Bacillus_virus	5.4e-20	27.1
AVD57293.1\|3011570_3012539_-	C-terminal binding protein	A0A1B1IVB5	uncultured_Mediterranean_phage	1.5e-14	26.5
AVD57294.1\|3012570_3012978_-	DUF126 domain-containing protein	NA	NA	NA	NA
AVD57295.1\|3012977_3014180_-	DUF521 domain-containing protein	NA	NA	NA	NA
AVD57296.1\|3014195_3015548_-	S-adenosylhomocysteine deaminase	NA	NA	NA	NA
AVD57297.1\|3016846_3017758_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
AVD57298.1\|3019194_3020139_-	ribose ABC transporter permease	NA	NA	NA	NA
AVD57299.1\|3020680_3021991_+\|transposase	transposase	NA	NA	NA	NA
AVD57300.1\|3022337_3024023_-\|transposase	IS4 family transposase	NA	NA	NA	NA
AVD57301.1\|3025309_3026380_-	5-methylcytosine-specific restriction endonuclease system specificity protein McrC	NA	NA	NA	NA
AVD57302.1\|3026366_3028781_-	restriction endonuclease	K4I1H4	Acidithiobacillus_phage	2.4e-18	27.6
AVD57303.1\|3028828_3031912_-	deoxyribonuclease HsdR	A0A220A398	Liberibacter_phage	1.0e-24	23.3
AVD57304.1\|3031927_3033187_-	restriction endonuclease subunit S	NA	NA	NA	NA
AVD57305.1\|3033186_3035751_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.9e-110	45.4
AVD57306.1\|3036075_3036378_-	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
AVD57307.1\|3036693_3036891_-	hypothetical protein	NA	NA	NA	NA
AVD57308.1\|3037043_3037688_-	lysine transporter LysE	NA	NA	NA	NA
AVD57309.1\|3038072_3038546_+	glutathione peroxidase	NA	NA	NA	NA
AVD57310.1\|3038713_3039202_-	PTS glucose transporter subunit IIA	NA	NA	NA	NA
AVD57894.1\|3039754_3040546_-	maltose-6'-phosphate glucosidase	NA	NA	NA	NA
AVD57311.1\|3040722_3042138_+\|transposase	ISLre2-like element ISBco6 family transposase	NA	NA	NA	NA
AVD57312.1\|3042525_3043830_+\|transposase	IS1380-like element ISBco2 family transposase	NA	NA	NA	NA
3043523:3043541	attL	NA	NA	NA	NA
AVD57313.1\|3044052_3045042_+	LD-carboxypeptidase	NA	NA	NA	NA
AVD57314.1\|3045624_3047088_-\|transposase	transposase	NA	NA	NA	NA
AVD57315.1\|3047987_3049244_-	glutamate:protein symporter	NA	NA	NA	NA
AVD57316.1\|3050399_3050963_-	YqcI/YcgG family protein	NA	NA	NA	NA
AVD57317.1\|3051288_3051864_-\|integrase	site-specific integrase	A0A1B0T6D2	Bacillus_phage	2.9e-26	39.3
AVD57318.1\|3052052_3054188_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	0.0e+00	84.7
AVD57319.1\|3054180_3054549_-	transcriptional regulator	E4ZFI8	Streptococcus_phage	2.6e-49	77.0
AVD57320.1\|3056045_3057509_-\|transposase	transposase	NA	NA	NA	NA
AVD57895.1\|3058072_3058969_+	LysR family transcriptional regulator	NA	NA	NA	NA
AVD57321.1\|3059608_3060085_-	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0A8WJI9	Clostridium_phage	1.3e-37	50.3
AVD57322.1\|3060081_3061953_-	anaerobic ribonucleoside triphosphate reductase	A0A2R2ZH54	Clostridioides_phage	1.4e-157	45.7
AVD57323.1\|3062675_3063755_-	hypothetical protein	NA	NA	NA	NA
AVD57324.1\|3063892_3064942_-	butanediol dehydrogenase	NA	NA	NA	NA
AVD57325.1\|3065390_3066416_+	hypothetical protein	NA	NA	NA	NA
AVD57326.1\|3066655_3067801_-	glycerate kinase	W6LM47	Streptococcus_phage	9.4e-45	38.2
AVD57327.1\|3067813_3069109_-	gluconate:proton symporter	NA	NA	NA	NA
AVD57328.1\|3069966_3070887_-	ribose ABC transporter substrate-binding protein RbsB	NA	NA	NA	NA
AVD57329.1\|3070902_3071847_-	ribose ABC transporter permease	NA	NA	NA	NA
AVD57330.1\|3071830_3073330_-	sugar ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.1e-11	24.8
AVD57331.1\|3073376_3073772_-	D-ribose pyranase	NA	NA	NA	NA
AVD57332.1\|3073768_3074650_-	ribokinase	NA	NA	NA	NA
AVD57333.1\|3074652_3075630_-	LacI family transcriptional regulator	NA	NA	NA	NA
AVD57334.1\|3076638_3077532_-\|transposase	transposase	NA	NA	NA	NA
AVD57335.1\|3077748_3078237_-	general stress protein	NA	NA	NA	NA
AVD57336.1\|3078435_3078699_-	hypothetical protein	NA	NA	NA	NA
AVD57337.1\|3078700_3079654_-\|transposase	transposase	NA	NA	NA	NA
AVD57338.1\|3080033_3080648_-	DUF1775 domain-containing protein	NA	NA	NA	NA
AVD57339.1\|3080816_3082463_-	copper resistance protein CopC	NA	NA	NA	NA
AVD57340.1\|3082874_3083798_-	ribokinase	NA	NA	NA	NA
AVD57341.1\|3083851_3084571_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
AVD57342.1\|3084775_3085771_-	LacI family transcriptional regulator	C6ZCU4	Enterobacteria_phage	3.3e-30	33.3
AVD57896.1\|3086270_3087722_+	PTS galactitol transporter subunit IIC	NA	NA	NA	NA
AVD57343.1\|3087970_3088300_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
AVD57344.1\|3088754_3090185_-	sensor histidine kinase	NA	NA	NA	NA
AVD57345.1\|3090208_3091408_-	beta-ketoacyl synthase	NA	NA	NA	NA
AVD57346.1\|3091743_3091944_+	cold-shock protein	Q9AZD3	Lactococcus_phage	9.0e-20	69.7
AVD57347.1\|3092126_3093542_-	GntR family transcriptional regulator	NA	NA	NA	NA
AVD57348.1\|3093781_3094615_+	EamA family transporter	NA	NA	NA	NA
AVD57349.1\|3094733_3095993_+	MFS transporter	NA	NA	NA	NA
AVD57350.1\|3096194_3096497_+	hypothetical protein	NA	NA	NA	NA
AVD57351.1\|3096479_3097418_-	EamA-like transporter family protein	NA	NA	NA	NA
AVD57352.1\|3098037_3099798_+	beta-N-acetylhexosaminidase	NA	NA	NA	NA
AVD57353.1\|3099813_3101469_+	serine hydrolase	NA	NA	NA	NA
AVD57354.1\|3101483_3102746_+	DUF1343 domain-containing protein	NA	NA	NA	NA
AVD57355.1\|3102973_3103336_+	hypothetical protein	NA	NA	NA	NA
AVD57356.1\|3103325_3103739_+	hypothetical protein	NA	NA	NA	NA
AVD57357.1\|3103791_3105654_-	multidrug ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.2e-66	33.1
AVD57358.1\|3105628_3107383_-	ABC transporter	W8CYL7	Bacillus_phage	7.9e-51	31.1
AVD57359.1\|3107424_3107883_-	MarR family transcriptional regulator	NA	NA	NA	NA
AVD57360.1\|3108271_3108850_-	phosphoglycolate phosphatase	NA	NA	NA	NA
AVD57361.1\|3109141_3110455_+\|transposase	IS1380-like element ISBco1 family transposase	A0A1X9I6F6	Streptococcus_phage	7.1e-113	48.8
3110142:3110160	attR	NA	NA	NA	NA

DBSCAN-SWA_10

3166784 : 3208992

Catovirus(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVD57408.1\|3166784_3168470_+\|transposase	IS4 family transposase	NA	NA	NA	NA
AVD57409.1\|3168618_3169239_+	bifunctional 2-keto-4-hydroxyglutarate aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase	NA	NA	NA	NA
AVD57410.1\|3169509_3170073_-	ECF transporter S component	NA	NA	NA	NA
AVD57411.1\|3170084_3170840_-	DUF4430 domain-containing protein	NA	NA	NA	NA
AVD57412.1\|3170846_3172355_-	terpene cyclase	NA	NA	NA	NA
AVD57413.1\|3172805_3174116_+\|transposase	transposase	NA	NA	NA	NA
AVD57414.1\|3174436_3176314_+	molecular chaperone HtpG	A0A1V0SAD6	Catovirus	8.6e-96	34.9
AVD57415.1\|3176879_3177290_-	TIGR01741 family protein	NA	NA	NA	NA
AVD57416.1\|3177781_3178831_+\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	1.5e-25	27.8
AVD57417.1\|3179159_3179765_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
AVD57418.1\|3179806_3180928_-	FAD-binding oxidoreductase	NA	NA	NA	NA
AVD57419.1\|3181846_3182869_-	alcohol dehydrogenase AdhP	A0A2K9L339	Tupanvirus	4.8e-24	23.9
AVD57420.1\|3184760_3184970_+	hypothetical protein	NA	NA	NA	NA
AVD57421.1\|3188425_3189199_+	3-oxoacyl-ACP reductase	NA	NA	NA	NA
AVD57422.1\|3189720_3190551_+	DUF1835 domain-containing protein	NA	NA	NA	NA
AVD57423.1\|3190821_3191526_-	DUF2961 domain-containing protein	NA	NA	NA	NA
AVD57424.1\|3191608_3193294_+\|transposase	IS4 family transposase	NA	NA	NA	NA
AVD57899.1\|3193405_3193804_-	DUF2961 domain-containing protein	NA	NA	NA	NA
AVD57425.1\|3193941_3195546_-	hypothetical protein	NA	NA	NA	NA
AVD57426.1\|3195526_3196201_-	hypothetical protein	NA	NA	NA	NA
AVD57427.1\|3196223_3197045_-	PTS mannose transporter subunit IID	NA	NA	NA	NA
AVD57428.1\|3197041_3197842_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
AVD57429.1\|3197854_3198346_-	PTS mannose/fructose/sorbose transporter subunit IIB	NA	NA	NA	NA
AVD57430.1\|3198357_3198798_-	PTS fructose transporter subunit IIA	NA	NA	NA	NA
AVD57431.1\|3201742_3203104_+\|transposase	IS4 family transposase	NA	NA	NA	NA
AVD57432.1\|3203264_3203489_-	hypothetical protein	NA	NA	NA	NA
AVD57433.1\|3203744_3203948_+	hypothetical protein	NA	NA	NA	NA
AVD57434.1\|3203962_3204499_+	cysteine hydrolase	NA	NA	NA	NA
AVD57435.1\|3204683_3205190_+	RNA-binding protein	NA	NA	NA	NA
AVD57436.1\|3205411_3206434_-	hypothetical protein	NA	NA	NA	NA
AVD57437.1\|3207768_3208992_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	3.7e-79	46.5

DBSCAN-SWA_11

3236915 : 3245230

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVD57457.1\|3236915_3237509_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.4e-29	40.3
AVD57458.1\|3237501_3238545_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	2.9e-61	45.6
AVD57459.1\|3238564_3239989_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	6.0e-49	33.7
AVD57460.1\|3239973_3242223_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.7e-168	44.2
AVD57461.1\|3242206_3242890_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AVD57462.1\|3242886_3243141_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AVD57463.1\|3243133_3243844_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D7SS43	Cyanophage	7.4e-48	42.8
AVD57464.1\|3243934_3245230_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	6.5e-18	33.5

DBSCAN-SWA_12

3428015 : 3490215

Bacillus_phage(20.0%)

tRNA,transposase,protease,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVD57629.1\|3428015_3429326_-\|transposase	transposase	NA	NA	NA	NA
AVD57630.1\|3429553_3430834_-	transcription termination factor Rho	NA	NA	NA	NA
AVD57631.1\|3431270_3432236_-	fructose-bisphosphatase class II	NA	NA	NA	NA
AVD57632.1\|3432345_3433632_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
AVD57633.1\|3433811_3434459_-	fructose-6-phosphate aldolase	A0A1D7SX77	Cyanophage	4.1e-53	52.6
AVD57634.1\|3434759_3435617_-	fructose-1,6-bisphosphate aldolase, class II	NA	NA	NA	NA
AVD57635.1\|3435828_3436194_-	response regulator	W8CYM9	Bacillus_phage	3.9e-13	37.1
AVD57636.1\|3436388_3437534_-	hypothetical protein	NA	NA	NA	NA
AVD57637.1\|3437546_3438380_-	hypothetical protein	NA	NA	NA	NA
AVD57638.1\|3438376_3439066_-	ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	4.2e-08	24.2
AVD57639.1\|3439058_3439463_-	GntR family transcriptional regulator	NA	NA	NA	NA
AVD57640.1\|3439733_3441335_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.0e-150	51.4
AVD57641.1\|3441565_3442150_-	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
AVD57642.1\|3442265_3442472_-	hypothetical protein	NA	NA	NA	NA
AVD57643.1\|3442903_3444319_-\|transposase	ISLre2-like element ISBco6 family transposase	NA	NA	NA	NA
AVD57644.1\|3444993_3445674_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.1e-28	33.5
AVD57645.1\|3449621_3451307_+\|transposase	IS4 family transposase	NA	NA	NA	NA
AVD57646.1\|3452304_3455559_-	methylmalonyl-CoA mutase	NA	NA	NA	NA
AVD57647.1\|3455644_3456280_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AVD57648.1\|3456299_3457442_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
AVD57649.1\|3457475_3458612_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
AVD57650.1\|3458653_3459832_-	acetyl-CoA C-acyltransferase	NA	NA	NA	NA
AVD57651.1\|3460559_3462704_-	4Fe-4S dicluster domain-containing protein	NA	NA	NA	NA
AVD57652.1\|3462915_3464115_+	cardiolipin synthase	NA	NA	NA	NA
AVD57653.1\|3464393_3466064_-\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
AVD57654.1\|3466060_3466501_-	DUF1934 domain-containing protein	NA	NA	NA	NA
AVD57655.1\|3466656_3467529_-	agmatinase	NA	NA	NA	NA
AVD57907.1\|3467709_3469761_+	penicillin-binding protein	NA	NA	NA	NA
AVD57656.1\|3469863_3470376_-	hypothetical protein	NA	NA	NA	NA
AVD57657.1\|3470406_3471069_-\|protease	site-2 protease family protein	NA	NA	NA	NA
AVD57908.1\|3471184_3471400_+	4-oxalocrotonate tautomerase	NA	NA	NA	NA
AVD57658.1\|3471414_3471933_-	hypothetical protein	NA	NA	NA	NA
AVD57659.1\|3471950_3473267_-	HD domain-containing protein	E3T4P8	Cafeteria_roenbergensis_virus	6.6e-26	27.7
AVD57660.1\|3473695_3474406_+	RsfA family transcriptional regulator	A0A1D6X8E5	Bacillus_phage	4.1e-06	50.0
AVD57661.1\|3477719_3478691_-	phosphate acetyltransferase	NA	NA	NA	NA
AVD57662.1\|3478860_3479616_+	heme-dependent peroxidase	NA	NA	NA	NA
AVD57663.1\|3480264_3480636_-	DUF423 domain-containing protein	NA	NA	NA	NA
AVD57664.1\|3480807_3481065_-	hypothetical protein	NA	NA	NA	NA
AVD57665.1\|3481515_3482202_-	uracil-DNA glycosylase	S4VZ65	Pandoravirus	5.8e-50	45.5
AVD57666.1\|3482349_3482697_+	general stress protein	NA	NA	NA	NA
AVD57667.1\|3482821_3483094_-	XRE family transcriptional regulator	NA	NA	NA	NA
AVD57668.1\|3483573_3483801_+\|bacteriocin	circular bacteriocin, circularin A/uberolysin family	NA	NA	NA	NA
AVD57669.1\|3483875_3485501_+	hypothetical protein	NA	NA	NA	NA
AVD57670.1\|3485546_3486065_+	stage II sporulation protein M	NA	NA	NA	NA
AVD57671.1\|3486061_3486748_+	ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	3.3e-13	28.8
AVD57672.1\|3486984_3487224_-	hypothetical protein	NA	NA	NA	NA
AVD57673.1\|3487303_3487948_-	ABC-2 transporter permease	NA	NA	NA	NA
AVD57909.1\|3487953_3488715_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.6e-16	29.5
AVD57674.1\|3488694_3490215_+\|transposase	IS5-like element ISBco3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_13

3583408 : 3591471

Staphylococcus_phage(66.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVD57751.1\|3583408_3583903_-	single-stranded DNA-binding protein	A8ATZ7	Listeria_phage	2.8e-54	67.7
AVD57752.1\|3583964_3584252_-	30S ribosomal protein S6	NA	NA	NA	NA
AVD57753.1\|3584505_3584976_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	2.2e-40	55.9
AVD57754.1\|3584988_3586182_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	7.1e-112	54.1
AVD57755.1\|3586199_3586847_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	8.8e-40	44.8
AVD57913.1\|3586827_3588048_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	2.4e-54	37.0
AVD57756.1\|3588270_3589371_-	redox-regulated ATPase YchF	NA	NA	NA	NA
AVD57757.1\|3589531_3589732_-	DUF951 domain-containing protein	NA	NA	NA	NA
AVD57758.1\|3589721_3590633_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
AVD57759.1\|3590847_3591471_+\|protease	spore protease YyaC	G3M9W0	Bacillus_virus	3.6e-22	38.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP026649

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection