CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP026648	Vibrio cholerae O1 biovar El Tor strain HC1037 chromosome II, complete sequence	0 crisprs	csa3,cas3	0	0	0	0
CP026647	Vibrio cholerae O1 biovar El Tor strain HC1037 chromosome I, complete sequence	0 crisprs	csa3,DEDDh,cas3,WYL,DinG,csx1,RT	0	0	6	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

92125 : 154224

Escherichia_phage(16.67%)

integrase,transposase

attL 152759:152772|attR 154475:154488

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVH50843.1\|92125_95104_+\|transposase	Tn3 family transposase	NA	NA	NA	NA
AVH50844.1\|95218_95410_+	hypothetical protein	A0A2I7RTF0	Vibrio_phage	1.8e-09	50.0
AVH50845.1\|95521_97015_+\|transposase	IS91 family transposase	NA	NA	NA	NA
AVH50846.1\|97045_97930_+	DUF3363 domain-containing protein	NA	NA	NA	NA
AVH50847.1\|98146_99361_+	chloramphenicol/florfenicol efflux MFS transporter FloR	S4TR35	Salmonella_phage	4.2e-19	28.7
AVH50848.1\|99388_99694_+	LysR family transcriptional regulator	NA	NA	NA	NA
AVH50849.1\|99805_100345_+\|transposase	IS91 family transposase	NA	NA	NA	NA
AVH50850.1\|100316_101153_-	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
AVH50851.1\|101152_101956_-	APH(3'') family aminoglycoside O-phosphotransferase	Q75ZG1	Hepacivirus	3.8e-24	34.3
AVH50852.1\|102016_102832_-	sulfonamide-resistant dihydropteroate synthase Sul2	NA	NA	NA	NA
AVH50853.1\|104646_105858_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	4.2e-51	51.4
AVH50854.1\|107444_108215_+	hypothetical protein	NA	NA	NA	NA
AVH50855.1\|108249_109065_+	abortive phage resistance protein	NA	NA	NA	NA
AVH50856.1\|109186_111337_+	phosphohydrolase	NA	NA	NA	NA
AVH50857.1\|111385_113206_+	conjugal transfer protein	NA	NA	NA	NA
AVH50858.1\|113215_113776_+	conjugative transfer protein	NA	NA	NA	NA
AVH50859.1\|113762_114398_+	DUF4400 domain-containing protein	NA	NA	NA	NA
AVH50860.1\|114424_115012_-	plasmid-related protein	NA	NA	NA	NA
AVH50861.1\|115025_115265_-	hypothetical protein	NA	NA	NA	NA
AVH50862.1\|115300_115582_+	type IV conjugative transfer system protein TraL	NA	NA	NA	NA
AVH50863.1\|115578_116205_+	pilus assembly protein	NA	NA	NA	NA
AVH53419.1\|116188_117085_+	hypothetical protein	NA	NA	NA	NA
AVH50864.1\|117087_118377_+	conjugal transfer protein TraB	NA	NA	NA	NA
AVH50865.1\|118373_119024_+	conjugal transfer protein TraV	NA	NA	NA	NA
AVH50866.1\|119020_119407_+	hypothetical protein	NA	NA	NA	NA
AVH53420.1\|119627_120419_+	hypothetical protein	NA	NA	NA	NA
AVH50867.1\|120411_121350_+	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
AVH50868.1\|121481_122174_+	DsbC family protein	NA	NA	NA	NA
AVH50869.1\|122173_124573_+	type IV secretion system protein TraC	NA	NA	NA	NA
AVH50870.1\|124565_124913_+	plasmid-related protein	NA	NA	NA	NA
AVH53421.1\|124989_125409_+	S26 family signal peptidase	NA	NA	NA	NA
AVH50871.1\|125419_126544_+	pilus assembly protein	NA	NA	NA	NA
AVH50872.1\|126527_127556_+	conjugal transfer protein TraU	NA	NA	NA	NA
AVH50873.1\|127558_131251_+	conjugal transfer protein TraN	NA	NA	NA	NA
AVH53422.1\|131341_132907_-	ATPase	NA	NA	NA	NA
AVH50874.1\|133037_133793_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	5.5e-33	36.9
AVH53423.1\|133782_135282_-\|transposase	IS21 family transposase	NA	NA	NA	NA
AVH50875.1\|135389_136406_-	hypothetical protein	NA	NA	NA	NA
AVH50876.1\|136636_137320_-	deoxyribonuclease I	NA	NA	NA	NA
AVH50877.1\|137428_138031_-	hypothetical protein	NA	NA	NA	NA
AVH50878.1\|138398_138725_+	plasmid-related protein	NA	NA	NA	NA
AVH50879.1\|138740_139160_+	single-stranded DNA-binding protein	A0A0R6PHK0	Moraxella_phage	1.9e-19	41.4
AVH50880.1\|139239_140058_+	phage recombination protein Bet	A0A0N7C1T0	Escherichia_phage	1.4e-53	53.5
AVH50881.1\|140343_141360_+	endonuclease	U6C712	Ralstonia_phage	5.3e-07	37.4
AVH50882.1\|141569_142529_+	CbbQ/NirQ/NorQ/GpvN family protein	L7TKP0	Rhizobium_phage	6.5e-31	35.0
AVH50883.1\|142528_143296_+	hypothetical protein	NA	NA	NA	NA
AVH50884.1\|143394_144348_+	DUF3150 domain-containing protein	NA	NA	NA	NA
AVH50885.1\|144409_144850_+	hypothetical protein	NA	NA	NA	NA
AVH50886.1\|144919_146575_+	VWA domain-containing protein	L7TNG1	Rhizobium_phage	4.9e-10	30.2
AVH50887.1\|146659_147157_+	DNA repair protein RadC	NA	NA	NA	NA
AVH50888.1\|147156_147498_+	plasmid-related protein	NA	NA	NA	NA
AVH50889.1\|147588_148662_+	DNA primase	NA	NA	NA	NA
AVH50890.1\|148751_149459_+	hypothetical protein	NA	NA	NA	NA
AVH50891.1\|149730_150135_+	glyoxalase	NA	NA	NA	NA
AVH50892.1\|150131_150833_-	AraC family transcriptional regulator	NA	NA	NA	NA
AVH53424.1\|150932_151229_-	DUF1801 domain-containing protein	NA	NA	NA	NA
AVH50893.1\|151365_151776_-	XRE family transcriptional regulator	NA	NA	NA	NA
AVH50894.1\|151973_152369_-	hypothetical protein	NA	NA	NA	NA
AVH50895.1\|152503_152977_-	trimethoprim-resistant dihydrofolate reductase DfrA1	A0A140HLG8	Bacillus_phage	1.6e-19	34.4
152759:152772	attL	NA	NA	NA	NA
AVH50896.1\|153264_154224_+\|integrase	integron integrase	R4TQT9	Mycobacterium_phage	7.0e-09	45.0
AVH50896.1\|153264_154224_+\|integrase	integron integrase	R4TQT9	Mycobacterium_phage	7.0e-09	45.0
154475:154488	attR	NA	NA	NA	NA

DBSCAN-SWA_2

262444 : 269637

Faustovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVH50986.1\|262444_263659_+	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	1.1e-32	30.5
AVH50987.1\|263695_264079_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	78.2
AVH50988.1\|264139_264463_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	3.0e-25	50.5
AVH50989.1\|264511_265027_+	co-chaperone protein HscB	NA	NA	NA	NA
AVH50990.1\|265050_266901_+	chaperone protein HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	5.3e-106	41.1
AVH50991.1\|266914_267253_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
AVH50992.1\|267301_267496_+	Fe-S assembly protein IscX	NA	NA	NA	NA
AVH50993.1\|267715_269005_+	peptidase B	Q6GYZ8	Mycoplasma_phage	1.7e-34	34.3
AVH50994.1\|269208_269637_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.0e-20	38.4

DBSCAN-SWA_3

1024987 : 1040277

Vibrio_phage(42.11%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVH51637.1\|1024987_1025362_-	cholera enterotoxin subunit B	B9V4E7	Vibrio_virus	1.0e-64	100.0
AVH51638.1\|1025358_1026135_-	enterotoxin	A0A142I6Y0	Vibrio_phage	1.3e-151	100.0
AVH51639.1\|1026240_1027440_-	Zona occludens toxin	A0A142I6Z1	Vibrio_phage	5.3e-240	100.0
AVH51640.1\|1027436_1027730_-	hypothetical protein	A0A0F6YNQ7	Vibrio_phage	3.7e-46	100.0
AVH51641.1\|1027726_1029010_-	hypothetical protein	A0A142I701	Vibrio_phage	9.1e-222	100.0
AVH51642.1\|1029020_1029269_-	colonization factor	A0A0N7F140	Vibrio_phage	8.8e-33	100.0
AVH51643.1\|1029404_1029785_-	hypothetical protein	A0A0N9HJ67	Vibrio_phage	4.0e-69	100.0
AVH51644.1\|1029762_1030842_-	replication initiation factor family protein	U5TQR3	Satellite_phage	2.2e-213	100.0
AVH51645.1\|1030967_1031306_+	transcriptional regulator	U5TNA1	Satellite_phage	7.3e-54	100.0
AVH51646.1\|1031646_1031799_+	lipoate--protein ligase	B1B6U1	Vibrio_virus	4.0e-20	100.0
AVH51647.1\|1031817_1032042_-	RstC protein	U5TMI6	Satellite_phage	1.1e-34	100.0
AVH51648.1\|1032135_1032510_-	hypothetical protein	B9V3G5	Vibrio_virus	1.2e-68	100.0
AVH51649.1\|1032487_1033567_-	replication initiation factor family protein	U5TQR3	Satellite_phage	2.2e-213	100.0
AVH51650.1\|1033692_1034031_+	transcriptional regulator	U5TNA1	Satellite_phage	7.3e-54	100.0
AVH51651.1\|1034371_1034524_+	lipoate--protein ligase	B1B6U1	Vibrio_virus	2.0e-19	98.0
AVH51652.1\|1034520_1035105_-	DNA-binding protein	E3U9I9	Vibrio_phage	6.4e-114	100.0
AVH51653.1\|1035097_1035265_-	helicase	E3U9J0	Vibrio_phage	2.3e-13	100.0
AVH51654.1\|1035342_1036035_-	XRE family transcriptional regulator	NA	NA	NA	NA
AVH51655.1\|1036164_1036449_-	hypothetical protein	NA	NA	NA	NA
AVH51656.1\|1036453_1038019_-	replication protein	A7BJY2	Enterobacteria_phage	3.9e-57	32.3
AVH51657.1\|1038180_1038747_+	XRE family transcriptional regulator	NA	NA	NA	NA
AVH51658.1\|1039055_1040277_+\|transposase	IS3-like element ISVch4 family transposase	Q716C2	Shigella_phage	1.5e-117	65.1

DBSCAN-SWA_4

1390952 : 1397852

Vibrio_phage(83.33%)

tail,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVH51955.1\|1390952_1391159_-	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	1.9e-09	51.9
AVH51956.1\|1391272_1391749_+	DNA repair protein RadC	NA	NA	NA	NA
AVH51957.1\|1391978_1392674_-	chemotaxis protein	A0A2I7S9D9	Vibrio_phage	1.2e-18	35.4
AVH51958.1\|1392670_1393848_-\|transposase	IS3-like element ISVch4 family transposase	Q716C2	Shigella_phage	1.5e-117	65.1
AVH51959.1\|1393890_1394931_-\|tail	phage tail tape measure protein	A0A2I7S9D9	Vibrio_phage	2.6e-126	72.5
AVH51960.1\|1395065_1395425_-	hypothetical protein	A0A2I7S9E0	Vibrio_phage	3.7e-40	67.8
AVH51961.1\|1395473_1395851_-	6-phospho-beta-glucosidase	NA	NA	NA	NA
AVH51962.1\|1395905_1396484_-	glyoxalase	NA	NA	NA	NA
AVH51963.1\|1396502_1396823_-	transcriptional regulator	NA	NA	NA	NA
AVH51964.1\|1396809_1397184_-	transcriptional regulator	NA	NA	NA	NA
AVH51965.1\|1397585_1397852_-	regulator of ribonuclease activity A	M1Q554	Vibrio_phage	1.4e-07	33.8

DBSCAN-SWA_5

1876678 : 1883295

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVH52405.1\|1876678_1877149_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	6.8e-34	48.7
AVH52406.1\|1877413_1878523_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.7e-64	39.8
AVH52407.1\|1878563_1879217_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-31	38.2
AVH52408.1\|1879221_1880325_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.3e-43	33.1
AVH52409.1\|1880350_1880800_-	transcriptional regulator NrdR	NA	NA	NA	NA
AVH52410.1\|1880899_1882153_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.0e-100	49.5
AVH52411.1\|1882161_1883295_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.4e-64	40.4

DBSCAN-SWA_6

2957091 : 2964354

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVH53361.1\|2957091_2957883_+	5'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	8.4e-69	51.6
AVH53362.1\|2957875_2958502_+	protein-L-isoaspartate O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.0e-36	52.1
AVH53363.1\|2958501_2959437_+	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	7.8e-05	34.7
AVH53364.1\|2959510_2960518_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.0e-35	34.2
AVH53365.1\|2960610_2963199_-	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	2.2e-33	23.0
AVH53366.1\|2963466_2964354_-	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	4.1e-56	41.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage