CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP020656	Staphylococcus aureus strain K5 chromosome, complete genome	8 crisprs	DEDDh,DinG,cas3,WYL,csa3	5	3	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP020656_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020656_2

700928-701012

Orphan

Consensus_repeat	Method
CTTTTCGTCAGCTTCTATGTTGGGGCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020656_2

>merge|CP020656|2|700928-701012|CRISPRCasFinder
CTTTTCGTCAGCTTCTATGTTGGGGCCCACCCCAACTTGCACATTATAGTAAGCTGACTTTTCGTCAGCTTCTGTGTTGGGGCCC

>CP020656|2|2|700928-701012|CRISPRCasFinder
CTTTTCGTCAGCTTCTATGTTGGGGCCC	ACCCCAACTTGCACATTATAGTAAGCTGA
CTTTTCGTCAGCTTCTGTGTTGGGGCCC

Protein	Signature genes	Signature genes Name	Protein_function
CP020656.1\|AUW98245.1\|707406_708093_-\|competence-protein-ComE	unknown	unknown	gnl\|CDD\|224472
CP020656.1\|AUW98240.1\|701151_702975_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
CP020656.1\|AUW98232.1\|691035_691212_-\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
CP020656.1\|AUW98238.1\|697729_698356_-\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|237622
CP020656.1\|AUW98249.1\|709779_710349_-\|nicotinate-nicotinamide-nucleotide-adenylyltransferase	unknown	unknown	gnl\|CDD\|273101
CP020656.1\|AUW98244.1\|706853_707315_-\|ComE-operon-protein-2	unknown	unknown	gnl\|CDD\|131622
CP020656.1\|AUX00186.1\|699465_700590_-\|coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
CP020656.1\|AUW98243.1\|704647_706795_-\|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl\|CDD\|225212
CP020656.1\|AUW98242.1\|703616_704591_-\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|235511
CP020656.1\|AUX00185.1\|690109_690793_-\|serine-protease	unknown	unknown	gnl\|CDD\|223961
CP020656.1\|AUW98236.1\|694553_695693_-\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|237656
CP020656.1\|AUW98247.1\|708851_709205_-\|ribosome-silencing-factor-RsfS	unknown	unknown	gnl\|CDD\|223870
CP020656.1\|AUW98246.1\|708132_708849_-\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
CP020656.1\|AUW98237.1\|695828_697661_-\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
CP020656.1\|AUW98234.1\|692857_693610_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|224303
CP020656.1\|AUW98235.1\|693611_694550_-\|ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|283886
CP020656.1\|AUW98239.1\|698387_699365_-\|HrcA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|273017
CP020656.1\|AUW98248.1\|709205_709790_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|224627
CP020656.1\|AUW98241.1\|703320_703572_+\|30S-ribosomal-protein-S20	unknown	unknown	gnl\|CDD\|178943
CP020656.1\|AUW98233.1\|691504_692851_-\|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	unknown	unknown	gnl\|CDD\|223694

Protein	Function_ID	Function_description	E-value
CP020656.1\|AUW98245.1\|707406_708093_-\|competence-protein-ComE	gnl\|CDD\|224472	COG1555, ComEA, DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair].	2.53337e-32
CP020656.1\|AUW98240.1\|701151_702975_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
CP020656.1\|AUW98232.1\|691035_691212_-\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	1.15423e-10
CP020656.1\|AUW98238.1\|697729_698356_-\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|237622	PRK14140, PRK14140, heat shock protein GrpE; Provisional.	3.74407e-81
CP020656.1\|AUW98249.1\|709779_710349_-\|nicotinate-nicotinamide-nucleotide-adenylyltransferase	gnl\|CDD\|273101	TIGR00482, Probable_nicotinate-nucleotide_adenylyltransferase, nicotinate (nicotinamide) nucleotide adenylyltransferase. This model represents the predominant bacterial/eukaryotic adenylyltransferase for nicotinamide-nucleotide, its deamido form nicotinate nucleotide, or both. The first activity, nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1), synthesizes NAD by the salvage pathway, while the second, nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) synthesizes the immediate precursor of NAD by the de novo pathway. In E. coli, NadD activity is biased toward the de novo pathway while salvage activity is channeled through the multifunctional NadR protein, but this division of labor may be exceptional. The given name of this model, nicotinate (nicotinamide) nucleotide adenylyltransferase, reflects the lack of absolute specificity with respect to substrate amidation state in most species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides].	1.98239e-76
CP020656.1\|AUW98244.1\|706853_707315_-\|ComE-operon-protein-2	gnl\|CDD\|131622	TIGR02571, putative_dCMP_deaminase, ComE operon protein 2. This protein is found in the ComE operon for "late competence" as characterized in B. subtilis. Proteins in this family contain homology to a cytidine/deoxycytidine deaminase domain family (pfam00383), and may carry out this activity.	4.81051e-102
CP020656.1\|AUX00186.1\|699465_700590_-\|coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
CP020656.1\|AUW98243.1\|704647_706795_-\|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl\|CDD\|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	1.36441e-90
CP020656.1\|AUW98242.1\|703616_704591_-\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|235511	PRK05574, holA, DNA polymerase III subunit delta; Reviewed.	4.1415e-104
CP020656.1\|AUX00185.1\|690109_690793_-\|serine-protease	gnl\|CDD\|223961	COG1030, NfeD, Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones].	8.78003e-63
CP020656.1\|AUW98236.1\|694553_695693_-\|molecular-chaperone-DnaJ	gnl\|CDD\|237656	PRK14280, PRK14280, molecular chaperone DnaJ.	0
CP020656.1\|AUW98247.1\|708851_709205_-\|ribosome-silencing-factor-RsfS	gnl\|CDD\|223870	COG0799, COG0799, Uncharacterized homolog of plant Iojap protein [Function unknown].	5.95861e-47
CP020656.1\|AUW98246.1\|708132_708849_-\|SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.00559e-15
CP020656.1\|AUW98237.1\|695828_697661_-\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
CP020656.1\|AUW98234.1\|692857_693610_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|224303	COG1385, COG1385, Uncharacterized protein conserved in bacteria [Function unknown].	1.35142e-90
CP020656.1\|AUW98235.1\|693611_694550_-\|ribosomal-protein-L11-methyltransferase	gnl\|CDD\|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	1.29315e-132
CP020656.1\|AUW98239.1\|698387_699365_-\|HrcA-family-transcriptional-regulator	gnl\|CDD\|273017	TIGR00331, Heat-inducible_transcription_repressor_HrcA, heat shock gene repressor HrcA. HrcA represses the class I heat shock operons groE and dnaK; overproduction prevents induction of these operons by heat shock while deletion allows constitutive expression even at low temperatures. In Bacillus subtilis, hrcA is the first gene of the dnaK operon and so is itself a heat shock gene. [Regulatory functions, DNA interactions].	2.05887e-119
CP020656.1\|AUW98248.1\|709205_709790_-\|HAD-family-hydrolase	gnl\|CDD\|224627	COG1713, COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism].	8.54529e-80
CP020656.1\|AUW98241.1\|703320_703572_+\|30S-ribosomal-protein-S20	gnl\|CDD\|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	2.90501e-17
CP020656.1\|AUW98233.1\|691504_692851_-\|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	gnl\|CDD\|223694	COG0621, MiaB, 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis].	0

>CP020656.1|AUX00186.1|699465_700590_-|coproporphyrinogen-III-oxidase
MTVQSAYIHIPFCVRICTYCDFNKYFIQNQPVDEYLDALITEMSTAKYRNLKTMYVGGGTPTALSINQLERLLKAIRDTFTITGEYTFEANPDELTKEKVQLLEKYGVNRISMGVQTFKPELLSVLGRTHNTEDIYTSVLNAKNAGIKSISLDLMYHLPKQTIEDFEQSLDLALDMDIQHISSYGLILEPKTQFYNMYRKGLLKLPNEDLGADMYQLLMSKIEQSPFHQYEISNFALDGHESEHNKVYWFNEEYYGFGAGASGYVDGVRYTNINPVNHYIKAINKESKAILVSNKPSLTERMEEEMFLGLRLNEGVSSSRFKKKFDQSIESVFGQTINNLKEKELIVEKNDAIALTKRGKVIGNEVFEAFLIND
>CP020656.1|AUW98239.1|698387_699365_-|HrcA-family-transcriptional-regulator
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW
>CP020656.1|AUW98238.1|697729_698356_-|nucleotide-exchange-factor-GrpE
MTNKDESVEKNTESTVEETNIKQNIDDSVEQAEESKGHLQDEAIEETSDENVIEEIDPKDQKINELQQLADENEEKYLRLYAEFENYKRRIQKENEINKTYQAQRVLTDILPAIDNIERALQIEGDDETFKSLQKGVQMVHESLINALKDNGLEVIKTEGEAFDPNIHQAVVQDDNPDFESGEITQELQKGYKLKDRVLRPSMVKVNQ
>CP020656.1|AUW98237.1|695828_697661_-|molecular-chaperone-DnaK
MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAESYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKDEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFEELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSKSQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDKNGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNEADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFKEVKDDDKK
>CP020656.1|AUW98236.1|694553_695693_-|molecular-chaperone-DnaJ
MAKRDYYEVLGISKDASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDDNKRASYDQFGHDGPQGFGGQGFNGSDFGGFSGFGGGGFEDIFSSFFGGGRQRDPNAPQKGDDLQYTMTLTFEEAVFGTTKEISIRKDVTCETCHGDGAKPGTSKKTCSYCNGAGHVAVEQNTILGRVRTEQVCPKCNGSGQEFEEACPTCHGKGTENKTVKLEVKVPEGVDNEQQIRLAGEGSPGVNGGPAGDLYVVFRVKPSETFKRDGDDIYYKLNVSFPQAALGDEIKIPTLNNEVMLTIPAGTQTGKQFRLKEKGIKNVHGYGYGDLYVDIKVVTPTKLTDRQKELMKEFAQLNGEEINEQPSNFKDRAKRFFKGE
>CP020656.1|AUW98235.1|693611_694550_-|ribosomal-protein-L11-methyltransferase
MNWTELSIIINHEAVELATNILENHGLNGVVIEDSDDLINQPEDKYGEIYALKKEDYPDKGVRLKAYFNEMTYDDKLRQQIKDELLNLDELDQHNIQFSEQIIAETDWENEWKNYFHPFRASKKFTIVPSWETYAKEADEELCIELDPGMAFGTGDHPTTSMCLKAIETYVLPQHSVIDVGTGSGILSIASHLIGVKRIKALDIDEMAVSVAKENFRRNHCETLIEAVPGNLLKDETEKFDIVIANILAHIIDEMIEDAYNTLNEGGYFITSGIIKEKYEGIQSHMERVGFKIISEQHDNGWVCLVGQKVSE
>CP020656.1|AUW98234.1|692857_693610_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MQRYFIDQNADVSQRFFITKKEDIHHITNVMRYDVGSKIILTFNDQTVYLCEIADITSDKIEVDLKEKQNINTELPVDVTICSGLIKADKYEWLLQKATELGASSFIAVSMERSIVKLNEAKVAKKIERWQKIIKEAAEQSYRLVIPSIQFESNLKLICDTIDNYDYILIAYEEEAKDGELSNFKQTLQQFKAQDKVLMIFGPEGGLSENEISLFSNTSTVVGLGPRILRAETAPLYALSTISYEKELMG
>CP020656.1|AUW98233.1|691504_692851_-|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB
MSTVAFHTLGCKVNHYETEAIWQLFKEANYERVDFEANADVFVINTCTVTNTGDKKSRQIIRRAIRQNPDAVICVTGCYAQTSSAEIMEIPGVDVVVGTQDRHKLLGYIDEFRKERQPINGVGNIMKNRKYEELDVPYFTDRTRASLKIQEGCNNFCTFCIIPWARGLMRSRDPEKVVEQATQLVNSGYKEIVLTGIHTGGYGQDLKDYNLAQLLRDLETINGLERIRISSIEASQLTDEVIDVLERSTKVVRHLHIPLQSGSDTVLKRMRRKYTMDRFSERLTKLHKALPDLAVTSDVIVGFPGETEAEFQETYDFIVKHKFSELHVFPYSPRIGTPAARMDDQIDEEIKNERVHKLITLSNQLGKLYASKFDQDVLEVIPEEQGDTEGTLVGYADNYMKVQFEGDESLIGQIVKVKITQANYPLNEGQAIKVVDFATNKSDREVLV
>CP020656.1|AUW98232.1|691035_691212_-|30S-ribosomal-protein-S21
MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
>CP020656.1|AUX00185.1|690109_690793_-|serine-protease
MTTILESTAGDTWVEQVSNIIVQPIFTLILTCLTFLGFVYQLYSKKINAAGIIATLSLLILFLGFLIQGNVNMHSILIFSIGVILVVIELFVVGAVIGIIGMILITISITTLGDNLLFMLANVIVALILTIVEWVILVKIFNRKIPFLDKVILKDSTNSESGYNSHDNRSHLVGKTAQTVTDLRPAGIIFCENERIDAVSDGNFILRNKTVKILEVEGTRVVVREVD
>CP020656.1|AUW98240.1|701151_702975_-|elongation-factor-4
MDNEQRLKRRENIRNFSIIAHIDHGKSTLADRILENTKSVETRDMQDQLLDSMDLERERGITIKLNAVRLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNELELMPVINKIDLPAAEPERVKQEIEDMIGLDQDDVVLASAKSNIGIEEILEKIVEVVPAPDGDPEAPLKALIFDSEYDPYRGVISSIRIVDGVVKAGDKIRMMATGKEFEVTEVGINTPKQLPVDELTVGDVGYIIASIKNVDDSRVGDTITLASRPASEPLQGYKKMNPMVYCGLFPIDNKNYNDLREALEKLQLNDASLEFEPESSQALGFGYRTGFLGMLHMEIIQERIEREFGIELIATAPSVIYQCILRDGSEVTVDNPAQMPDRDKIDKIFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVNIVYELPLAEVVFDFFDQLKSNTKGYASFDYEFIENKESNLVKMDILLNGDKVDALSFIVHRDFAYERGKALVEKLKTLIPRQQFEVPVQAAIGQKIVARTNIKSMGKNVLAKCYGGDISRKRKLLEKQKAGKAKMKAVGNVEIPQDAFLAVLKMDDE
>CP020656.1|AUW98241.1|703320_703572_+|30S-ribosomal-protein-S20
MANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAFSNNADNKNELVSLAVKLVDKAAQSNLIHSNKADRIKSQLMTANK
>CP020656.1|AUW98242.1|703616_704591_-|DNA-polymerase-III-subunit-delta
MSDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYETEIAPIVEETLTLPFFSDKKAILVKNAYIFTGEKAPKDMAHNVDQLIEFIEKYDGENLIVFEIYQNKLDERKKLTKTLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALDLFIELTGINFNIVSQEIEKLILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRKKEQAIHLVKDLITMKEEPIKLLALITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYRVKLALGQVRHYQLDELLNIVDACAETDYKLKSSYMDKQLILELFILSL
>CP020656.1|AUW98243.1|704647_706795_-|DNA-internalization-related-competence-protein-ComEC/Rec2
MLSTFLFILLLYIAYRKNKIVYAPTSLFLIIFSSWYLHYSQQAIFNYINYIERTSQFNERAQVIQIQRQDSDTYKGRLSLKNEIYPFFLTDKKNFDLKKIESRNCIVKGQFKVNENKFVTLKLQSIVVQSCLESNRSNLIEKHKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGITIIVLTLFAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQQLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYLVDLSFNFHDWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSILYEGGKNQNVLIDTGGKVIDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKGYSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLLKKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNLKVDSNSYGNASGL
>CP020656.1|AUW98244.1|706853_707315_-|ComE-operon-protein-2
MERIKWEEYFMAQSHLLALRSTCQRLSVGATIVKDNRIIAGGYNGSVAGEVHCIDEGCLIEDGHCIRTIHAEMNALLQCAKQGVSTEGATIYVTHFPCLNCTKSIIQAGIKRIYYAEDYHNHEYATKLLKQSGIEFKKIPFSPEYVAKYLTKG
>CP020656.1|AUW98245.1|707406_708093_-|competence-protein-ComE
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSKNKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKNGNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT
>CP020656.1|AUW98246.1|708132_708849_-|SAM-dependent-methyltransferase
MSQYAEMSLVYDQLTQDQPYEKWFEIVKNHCKDESKILDIGCGTGSLTVQLEALGNVTGMDLSVDMLTVAAQKSANVNWLEGDMTSFDLQQQFDIITIFCDSLNYLQDETAVIETFINVYHHLTDSGVFIFDVHTVYKMMTLFNNQSYIDDKGDIFLAWDAVQGDLPLSVYHDMTFFIRHEDETYSRFDESHFQRTFDEKTYLSWLAQVGFKHVETFTDFNIDEHNEDAERLFFIAKK
>CP020656.1|AUW98247.1|708851_709205_-|ribosome-silencing-factor-RsfS
MNSQELLAIAVDAIDNKKGEDTISLEMKGISDMTDYFVVTHGNNERQVQAIARAVKEVANEQNIEVKRMEGYNEARWILIDLADVVVHVFHKDERNYYNIEKLYQDAPLESYGQVAY
>CP020656.1|AUW98248.1|709205_709790_-|HAD-family-hydrolase
MNIEKAKRLAKEKLPEKRYNHSLRVSETAIKLAEIYDGDTSKVELAGVLHDFCKYDDLGKMYQIVRQYELGNDLLSYGSEILHGPVCAAIMEHEYGINDEEVLMAIKYHTTGRQQMTKTEKLIFIADYIEPGRTIPGVDDIRDMAYNQGSLDKTIYEISKRTVLFLIQKDITVYNKTIDCLNYYNYSDERIKDD
>CP020656.1|AUW98249.1|709779_710349_-|nicotinate-nicotinamide-nucleotide-adenylyltransferase
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHHDFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH

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Crispr_ID: CP020656_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020656_4

878811-878889

Orphan

Consensus_repeat	Method
TATTGTAAGCTGACTTTCCGCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020656_4

>merge|CP020656|4|878811-878889|CRISPRCasFinder
TATTGTAAGCTGACTTTCCGCCAGCCTCTGTGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTCCGCCA

>CP020656|4|4|878811-878889|CRISPRCasFinder
TATTGTAAGCTGACTTTCCGCCA	GCCTCTGTGTTGGGGCCCCGCCAACTTGCACAT
TATTGTAAGCTGACTTTCCGCCA

Protein	Signature genes	Signature genes Name	Protein_function
CP020656.1\|AUW98409.1\|885333_887739_+\|Na+/H+-antiporter-subunit-A	unknown	unknown	gnl\|CDD\|237155
CP020656.1\|AUX00192.1\|888171_888501_+\|Na(+)/H(+)-antiporter-subunit-C	unknown	unknown	gnl\|CDD\|181497
CP020656.1\|AUW98396.1\|871583_872108_-\|inactive-signal-peptidase-IA	unknown	unknown	gnl\|CDD\|274044
CP020656.1\|AUW98410.1\|887731_888160_+\|Na+/H+-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
CP020656.1\|AUW98399.1\|874694_875900_+\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
CP020656.1\|AUW98393.1\|863702_867356_-\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
CP020656.1\|AUW98402.1\|878556_878715_+\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUW98398.1\|873012_874344_-\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
CP020656.1\|AUW98401.1\|877510_878440_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
CP020656.1\|AUW98404.1\|880383_881574_-\|Ornithine-aminotransferase-2	unknown	unknown	gnl\|CDD\|179736
CP020656.1\|AUW98400.1\|875889_877269_+\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
CP020656.1\|AUW98407.1\|884162_884756_-\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|238908
CP020656.1\|AUW98403.1\|879030_880275_-\|NAD-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
CP020656.1\|AUW98395.1\|870992_871568_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
CP020656.1\|AUW98411.1\|888493_889990_+\|Na+/H+-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
CP020656.1\|AUW98394.1\|867356_870833_-\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736
CP020656.1\|AUW98408.1\|884819_885203_+\|kinase	unknown	unknown	gnl\|CDD\|378054
CP020656.1\|AUW98397.1\|872112_872688_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
CP020656.1\|AUW98406.1\|883370_883748_-\|general-stress-protein	unknown	unknown	gnl\|CDD\|224023
CP020656.1\|AUW98405.1\|881882_883010_-\|NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086

Protein	Function_ID	Function_description	E-value
CP020656.1\|AUW98409.1\|885333_887739_+\|Na+/H+-antiporter-subunit-A	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
CP020656.1\|AUX00192.1\|888171_888501_+\|Na(+)/H(+)-antiporter-subunit-C	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	3.20641e-61
CP020656.1\|AUW98396.1\|871583_872108_-\|inactive-signal-peptidase-IA	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.81012e-49
CP020656.1\|AUW98410.1\|887731_888160_+\|Na+/H+-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
CP020656.1\|AUW98399.1\|874694_875900_+\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
CP020656.1\|AUW98393.1\|863702_867356_-\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
CP020656.1\|AUW98406.1\|883370_883748_-\|general-stress-protein	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
CP020656.1\|AUW98398.1\|873012_874344_-\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
CP020656.1\|AUW98401.1\|877510_878440_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	5.11302e-151
CP020656.1\|AUW98404.1\|880383_881574_-\|Ornithine-aminotransferase-2	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
CP020656.1\|AUW98400.1\|875889_877269_+\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
CP020656.1\|AUW98407.1\|884162_884756_-\|peptidylprolyl-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
CP020656.1\|AUW98403.1\|879030_880275_-\|NAD-specific-glutamate-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
CP020656.1\|AUW98395.1\|870992_871568_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	3.45225e-53
CP020656.1\|AUW98411.1\|888493_889990_+\|Na+/H+-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
CP020656.1\|AUW98394.1\|867356_870833_-\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
CP020656.1\|AUW98408.1\|884819_885203_+\|kinase	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	8.96507e-53
CP020656.1\|AUW98397.1\|872112_872688_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.01759e-40
CP020656.1\|AUW98405.1\|881882_883010_-\|NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0

>CP020656.1|AUW98402.1|878556_878715_+|hypothetical-protein
MIFSQNLFRRPTPARLTRIEKSLLQAHFRSVNYCQYNFVEHRTLIYVPAWFN
>CP020656.1|AUW98401.1|877510_878440_+|glycerophosphodiester-phosphodiesterase
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>CP020656.1|AUW98400.1|875889_877269_+|argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFIILSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>CP020656.1|AUW98399.1|874694_875900_+|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>CP020656.1|AUW98398.1|873012_874344_-|glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEDNIAYQYATIRNILYAKGFTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>CP020656.1|AUW98397.1|872112_872688_-|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE
>CP020656.1|AUW98396.1|871583_872108_-|inactive-signal-peptidase-IA
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDHDNNQHDSRQFGLIDKKDIIGNISLRYYPFSKWTIQFKS
>CP020656.1|AUW98395.1|870992_871568_-|signal-peptidase-I
MKKELLEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTRGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>CP020656.1|AUW98394.1|867356_870833_-|helicase-exonuclease-AddAB-subunit-AddB
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRPEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDVLQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVFLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYIAMTRARQDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>CP020656.1|AUW98393.1|863702_867356_-|helicase-exonuclease-AddAB-subunit-AddA
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDIPYLTDHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYKAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDVAQVEDSSRPNVNISIIYFEDVSTETILDNNEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>CP020656.1|AUW98403.1|879030_880275_-|NAD-specific-glutamate-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>CP020656.1|AUW98404.1|880383_881574_-|Ornithine-aminotransferase-2
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>CP020656.1|AUW98405.1|881882_883010_-|NADH-dependent-flavin-oxidoreductase
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSNIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPVAVIEEVLKAKEAYGNKEFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIRKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>CP020656.1|AUW98406.1|883370_883748_-|general-stress-protein
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>CP020656.1|AUW98407.1|884162_884756_-|peptidylprolyl-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>CP020656.1|AUW98408.1|884819_885203_+|kinase
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHERKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>CP020656.1|AUW98409.1|885333_887739_+|Na+/H+-antiporter-subunit-A
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>CP020656.1|AUW98410.1|887731_888160_+|Na+/H+-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>CP020656.1|AUX00192.1|888171_888501_+|Na(+)/H(+)-antiporter-subunit-C
MIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>CP020656.1|AUW98411.1|888493_889990_+|Na+/H+-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGFYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK

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Crispr_ID: CP020656_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020656_5

1174671-1174764

Orphan

Consensus_repeat	Method
GGCTTTTATGCAGTTGCTGCACAAACAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020656_5

>merge|CP020656|5|1174671-1174764|CRISPRCasFinder
GGCTTTTATGCAGTTGCTGCACAAACAACTGTATTCCTTTACTCCCCTTGAGCTTTAGCGATTAGGGGCTCTTATGCAGTTGCTGCACAAACAA

>CP020656|5|5|1174671-1174764|CRISPRCasFinder
GGCTTTTATGCAGTTGCTGCACAAACAA	CTGTATTCCTTTACTCCCCTTGAGCTTTAGCGATTAGG
GGCTCTTATGCAGTTGCTGCACAAACAA

Protein	Signature genes	Signature genes Name	Protein_function
CP020656.1\|AUW98732.1\|1175784_1177446_-\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
CP020656.1\|AUW98723.1\|1165622_1165847_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378571
CP020656.1\|AUX00200.1\|1177442_1177826_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226896
CP020656.1\|AUW98730.1\|1171803_1172523_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
CP020656.1\|AUW98726.1\|1168542_1169331_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP020656.1\|AUX00199.1\|1173675_1174503_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563
CP020656.1\|AUW98727.1\|1169499_1170216_-\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUW98728.1\|1170377_1170884_-\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUW98725.1\|1167917_1168292_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
CP020656.1\|AUW98734.1\|1180192_1181488_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
CP020656.1\|AUW98731.1\|1174879_1175515_-\|endonuclease-III	unknown	unknown	gnl\|CDD\|225140
CP020656.1\|AUW98733.1\|1178134_1179145_-\|zinc-dependent-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|181842
CP020656.1\|AUX00198.1\|1172577_1173528_-\|enterobactin-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
CP020656.1\|AUW98737.1\|1182919_1183858_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|381309
CP020656.1\|AUW98736.1\|1182172_1182709_-\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223728
CP020656.1\|AUW98729.1\|1171019_1171820_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP020656.1\|AUW98724.1\|1166040_1166970_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225778
CP020656.1\|AUW98738.1\|1184127_1184754_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|335700
CP020656.1\|AUW98735.1\|1181527_1182004_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP020656.1\|AUX00201.1\|1179643_1180165_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378039

Protein	Function_ID	Function_description	E-value
CP020656.1\|AUW98732.1\|1175784_1177446_-\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
CP020656.1\|AUW98723.1\|1165622_1165847_+\|hypothetical-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	5.21775e-14
CP020656.1\|AUX00200.1\|1177442_1177826_-\|hypothetical-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	9.50091e-54
CP020656.1\|AUW98730.1\|1171803_1172523_-\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
CP020656.1\|AUX00199.1\|1173675_1174503_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	7.01611e-72
CP020656.1\|AUW98726.1\|1168542_1169331_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.55978e-34
CP020656.1\|AUW98731.1\|1174879_1175515_-\|endonuclease-III	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	9.55275e-93
CP020656.1\|AUW98735.1\|1181527_1182004_-\|N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
CP020656.1\|AUW98724.1\|1166040_1166970_+\|hypothetical-protein	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	6.82669e-36
CP020656.1\|AUW98734.1\|1180192_1181488_-\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.13106e-150
CP020656.1\|AUW98733.1\|1178134_1179145_-\|zinc-dependent-alcohol-dehydrogenase	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
CP020656.1\|AUX00198.1\|1172577_1173528_-\|enterobactin-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	5.19191e-48
CP020656.1\|AUW98737.1\|1182919_1183858_-\|oxidoreductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	1.82718e-167
CP020656.1\|AUW98736.1\|1182172_1182709_-\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
CP020656.1\|AUW98729.1\|1171019_1171820_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	4.57184e-26
CP020656.1\|AUW98725.1\|1167917_1168292_+\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
CP020656.1\|AUW98738.1\|1184127_1184754_-\|hypothetical-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	4.44435e-60
CP020656.1\|AUX00201.1\|1179643_1180165_-\|hypothetical-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98

>CP020656.1|AUX00199.1|1173675_1174503_-|ABC-transporter-substrate-binding-protein
MKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYAKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>CP020656.1|AUX00198.1|1172577_1173528_-|enterobactin-ABC-transporter-permease
MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVTGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>CP020656.1|AUW98730.1|1171803_1172523_-|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>CP020656.1|AUW98729.1|1171019_1171820_-|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLTLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTAAFINKHHNEKHV
>CP020656.1|AUW98728.1|1170377_1170884_-|hypothetical-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>CP020656.1|AUW98727.1|1169499_1170216_-|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>CP020656.1|AUW98726.1|1168542_1169331_-|alpha/beta-hydrolase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLKFLKSVS
>CP020656.1|AUW98725.1|1167917_1168292_+|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>CP020656.1|AUW98724.1|1166040_1166970_+|hypothetical-protein
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIILNIIINPKVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTLGLFGATIHDFNLIKAIGVLLLIIGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSIALLILTAIFNRSLKLKTSHLKFGKLKPIYFTSGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>CP020656.1|AUW98723.1|1165622_1165847_+|hypothetical-protein
MTKTLELSFKSSLDKPVKLQLPQLNNVVTEQVVRDSMNALVDLNIIKSNSGTITKVHSAQIIDKTTTVLFEDKK
>CP020656.1|AUW98731.1|1174879_1175515_-|endonuclease-III
MLGTDELYKLLYRHMGPQNWWPADNDIELMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>CP020656.1|AUW98732.1|1175784_1177446_-|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>CP020656.1|AUX00200.1|1177442_1177826_-|hypothetical-protein
MLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>CP020656.1|AUW98733.1|1178134_1179145_-|zinc-dependent-alcohol-dehydrogenase
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>CP020656.1|AUX00201.1|1179643_1180165_-|hypothetical-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>CP020656.1|AUW98734.1|1180192_1181488_-|HD-domain-containing-protein
MTNAFVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>CP020656.1|AUW98735.1|1181527_1182004_-|N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>CP020656.1|AUW98736.1|1182172_1182709_-|NAD(P)H-dependent-oxidoreductase
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>CP020656.1|AUW98737.1|1182919_1183858_-|oxidoreductase
MKQFVNLGKSDVEVLPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDDNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFIPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVIENIKAADIVLSDDEIQYIDELFPIED
>CP020656.1|AUW98738.1|1184127_1184754_-|hypothetical-protein
MLLCESKIINKNPKYRIIKYNDEYLMVDIISTWISLFFPFINWFIPKEYVKISREEFENLNIVKPAKKNVFWPVAGSSALLGVALRKYTHLLDIQLDKKLVIAICCITFIGILIFYVRLIKKSSLNIYNTKNKRSKIFLIPTLKNVCFTLFGYILFGGLTMLFLDALLSMSYQNIIVYFVWIAVIMGFFLVNIALIIDKNIHVILKNQ

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Crispr_ID: CP020656_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020656_6

2076786-2076876

Orphan

Consensus_repeat	Method
GGGCCCACACCCCAACTTGCATTGCCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020656_6

>merge|CP020656|6|2076786-2076876|CRISPRCasFinder
GGGCCCACACCCCAACTTGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTTTGTTGGGGCCCACACCCCAACTTGCATTGTCTGTAGAA

>CP020656|6|6|2076786-2076876|CRISPRCasFinder
GGGCCCACACCCCAACTTGCATTGCCTGTAGAA	TTTCTTTTCGAAATTCTCTTTGTTG
GGGCCCACACCCCAACTTGCATTGTCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP020656.1\|AUW99580.1\|2085018_2086758_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225814
CP020656.1\|AUW99582.1\|2087613_2088057_+\|antiholin-like-protein-LrgA	unknown	unknown	gnl\|CDD\|235222
CP020656.1\|AUW99583.1\|2088049_2088751_+\|antiholin-like-protein-LrgB	unknown	unknown	gnl\|CDD\|179810
CP020656.1\|AUW99566.1\|2067726_2068194_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
CP020656.1\|AUW99574.1\|2077297_2078467_+\|CDP-glycerol--glycerophosphate-glycerophosphotransferase	unknown	unknown	gnl\|CDD\|367953
CP020656.1\|AUX00241.1\|2067085_2067742_+\|transcription-antiterminator-BglG	unknown	unknown	gnl\|CDD\|334031
CP020656.1\|AUW99568.1\|2068721_2069981_+\|PTS-galactitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226298
CP020656.1\|AUW99575.1\|2078742_2079459_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|184017
CP020656.1\|AUW99569.1\|2069998_2071054_+\|sorbitol-dehydrogenase	unknown	unknown	gnl\|CDD\|176219
CP020656.1\|AUW99567.1\|2068216_2068495_+\|PTS-galactitol-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908
CP020656.1\|AUW99581.1\|2086760_2087501_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|184495
CP020656.1\|AUX00242.1\|2074705_2076247_+\|CDP-glycerol--poly(glycerophosphate)-glycerophosphotransferase	unknown	unknown	gnl\|CDD\|367953
CP020656.1\|AUW99579.1\|2084084_2084759_+\|iron-sulfur-cluster-repair-protein-ScdA	unknown	unknown	gnl\|CDD\|183940
CP020656.1\|AUW99578.1\|2082219_2083941_+\|glycosyl-transferase-family-2	unknown	unknown	gnl\|CDD\|376098
CP020656.1\|AUW99570.1\|2071055_2071202_+\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUW99571.1\|2071225_2072269_+\|galactitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|176198
CP020656.1\|AUW99572.1\|2072796_2073513_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|184017
CP020656.1\|AUW99577.1\|2080498_2082187_+\|CDP-glycerol--poly(glycerophosphate)-glycerophosphotransferase	unknown	unknown	gnl\|CDD\|367953
CP020656.1\|AUW99573.1\|2073505_2074531_+\|ribitol-5-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|176199
CP020656.1\|AUW99576.1\|2079451_2080477_+\|ribitol-5-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|176199

Protein	Function_ID	Function_description	E-value
CP020656.1\|AUW99580.1\|2085018_2086758_+\|sensor-histidine-kinase	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	0
CP020656.1\|AUW99582.1\|2087613_2088057_+\|antiholin-like-protein-LrgA	gnl\|CDD\|235222	PRK04125, PRK04125, antiholin-like protein LrgA.	8.44339e-64
CP020656.1\|AUW99583.1\|2088049_2088751_+\|antiholin-like-protein-LrgB	gnl\|CDD\|179810	PRK04288, PRK04288, antiholin-like protein LrgB; Provisional.	5.86643e-124
CP020656.1\|AUW99566.1\|2067726_2068194_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	1.75683e-37
CP020656.1\|AUW99574.1\|2077297_2078467_+\|CDP-glycerol--glycerophosphate-glycerophosphotransferase	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	1.25735e-161
CP020656.1\|AUX00241.1\|2067085_2067742_+\|transcription-antiterminator-BglG	gnl\|CDD\|334031	pfam00359, PTS_EIIA_2, Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.	3.62031e-24
CP020656.1\|AUW99568.1\|2068721_2069981_+\|PTS-galactitol-transporter-subunit-IIC	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	0
CP020656.1\|AUW99575.1\|2078742_2079459_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|184017	PRK13385, PRK13385, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Provisional.	2.28851e-105
CP020656.1\|AUW99569.1\|2069998_2071054_+\|sorbitol-dehydrogenase	gnl\|CDD\|176219	cd08258, Zn_ADH4, Alcohol dehydrogenases of the MDR family. This group shares the zinc coordination sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of an beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.42275e-146
CP020656.1\|AUW99567.1\|2068216_2068495_+\|PTS-galactitol-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	3.43648e-34
CP020656.1\|AUW99581.1\|2086760_2087501_+\|DNA-binding-response-regulator	gnl\|CDD\|184495	PRK14084, PRK14084, DNA-binding response regulator.	1.56134e-152
CP020656.1\|AUX00242.1\|2074705_2076247_+\|CDP-glycerol--poly(glycerophosphate)-glycerophosphotransferase	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	8.37895e-115
CP020656.1\|AUW99579.1\|2084084_2084759_+\|iron-sulfur-cluster-repair-protein-ScdA	gnl\|CDD\|183940	PRK13276, PRK13276, iron-sulfur cluster repair di-iron protein ScdA.	3.56125e-153
CP020656.1\|AUW99578.1\|2082219_2083941_+\|glycosyl-transferase-family-2	gnl\|CDD\|376098	pfam18674, TarS_C1, TarS beta-glycosyltransferase C-terminal domain 1. Beta-glycosyltransferase TarS is an enzyme responsible for the glycosylation of wall teichoic acid polymers of the S. aureus cell wall, a process that has been shown to be specifically responsible for methicillin resistance in MRSA. It contains a trimerization domain composed of tandem carbohydrate binding motifs.The two C-terminally localized regions composed of a series of beta-sheets participate in an extensive trimerization interface and they assume an immunoglobulin-like fold. It is suggested that both carbohydrate binding domains may be involved in polyRboP binding, however unlike pullulanase, the CBMs of TarS are involved in the formation of an extensive trimerization interface.	5.09942e-35
CP020656.1\|AUW99571.1\|2071225_2072269_+\|galactitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|176198	cd08236, sugar_DH, NAD(P)-dependent sugar dehydrogenases. This group contains proteins identified as sorbitol dehydrogenases and other sugar dehydrogenases of the medium-chain dehydrogenase/reductase family (MDR), which includes zinc-dependent alcohol dehydrogenase and related proteins. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Related proteins include threonine dehydrogenase, formaldehyde dehydrogenase, and butanediol dehydrogenase. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Horse liver alcohol dehydrogenase is a dimeric enzyme and each subunit has two domains. The NAD binding domain is in a Rossmann fold and the catalytic domain contains a zinc ion to which substrates bind. There is a cleft between the domains that closes upon formation of the ternary complex.	2.26749e-178
CP020656.1\|AUW99572.1\|2072796_2073513_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|184017	PRK13385, PRK13385, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Provisional.	4.88306e-125
CP020656.1\|AUW99577.1\|2080498_2082187_+\|CDP-glycerol--poly(glycerophosphate)-glycerophosphotransferase	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	4.42901e-119
CP020656.1\|AUW99573.1\|2073505_2074531_+\|ribitol-5-phosphate-dehydrogenase	gnl\|CDD\|176199	cd08237, ribitol-5-phosphate_DH, ribitol-5-phosphate dehydrogenase. NAD-linked ribitol-5-phosphate dehydrogenase, a member of the MDR/zinc-dependent alcohol dehydrogenase-like family, oxidizes the phosphate ester of ribitol-5-phosphate to xylulose-5-phosphate of the pentose phosphate pathway. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability.	2.19734e-179
CP020656.1\|AUW99576.1\|2079451_2080477_+\|ribitol-5-phosphate-dehydrogenase	gnl\|CDD\|176199	cd08237, ribitol-5-phosphate_DH, ribitol-5-phosphate dehydrogenase. NAD-linked ribitol-5-phosphate dehydrogenase, a member of the MDR/zinc-dependent alcohol dehydrogenase-like family, oxidizes the phosphate ester of ribitol-5-phosphate to xylulose-5-phosphate of the pentose phosphate pathway. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability.	0

>CP020656.1|AUX00242.1|2074705_2076247_+|CDP-glycerol--poly(glycerophosphate)-glycerophosphotransferase
MKIDGNTFLCRFNVAILDDGYYLPMDKYLFVYHDQLEYIGQLNPNIIDQAYAALNEEQIEEYNELTTQNGKANYVLANEAKVFRKGGVSQHTVYTITPEIASDVNEFVFDIEITLPQEKSGVIATSAHWLHKQGHKASFESRSFLFKAIFNITKLLHIKRSKTILFTSDSRPNLSGNFKYVYDELLRQKVDFDYDIQTVFKANITDRRKWRDKFRLPYLLGKADYIFVDDFHPLIYTVRFRPSQEIIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYVSSETDIPFYAEAFGIREENVVPTGVPRTDVLFDETYATQIKQEMEDELPIIKGKKVILFAPTFRGNGHGTAHYPFFKIDFERLARYCEKNNAVVLFKMHPFVKNRLNISREHRQYFIDVSDYREVNDILFVTDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPYESFVPGKIVQSFDALMDALDNEDYEVEKVVPFLDKHFKYQDGRSSERLVKDLFRR
>CP020656.1|AUW99573.1|2073505_2074531_+|ribitol-5-phosphate-dehydrogenase
MINQVYQLVAPRQFDVTYNNVDIYGNHVIVRPLYLSICAADQRYYTGRRDENVLRKKLPMSLVHEAVGEVVFDSKGVFEKGTKVVMVPNTPTEKHDVIAENYLPSSYFRSSGYDGFMQDYVVMAHDRIVLLPDDIDLSTISYTELVSVSYHAIQRFERKSIPLKTSFGIWGDGNLGYITAILLRKLYPEAKIYVFGKTDYKLSHFSFVDDIFTVNQIPADLKIDHAFECVGGKGSQVALQQIVEHISPEGSIALLGVSELPVEVNTRLVLEKGLTLIGSSRSGSKDFEQVVDLYRKYPDIVEKLALLKGHEINVCTMQDIVQAFEMDLSTSWGKTVLKWTI
>CP020656.1|AUW99572.1|2072796_2073513_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MIYAGILAGGIGSRMGNVPLPKQFLDIDNKPILIHTIEKFILVSEFNEIIIATPAQWISHTQDILKKYNITDQRVKVVAGGTDRNETIMNIIDYIRNVNGINNDDVIVTHDAVRPFLTQRIIKENIEVAEKYGAVDTVIEAIDTIVMSKDKQNIHSIAVRNEMYQGQTPQSFNIKLLQDSYRALSSAQKEILSDACKIIVESGHPVKLVRGELYNIKVTTPYDLKVANAIIQGDIADD
>CP020656.1|AUW99571.1|2071225_2072269_+|galactitol-1-phosphate-5-dehydrogenase
MKALKLYGVEDLRYEDNEKPVIESVNDVIVKVRATGICGSDTSRYKKMGPYIKGMPFGHEFSGVVDAIGSDVTHVNVGDKVTGCPAIPCYQCEYCLKGEYARCEKLFVIGSYEPGSFAEYVKLPAQNVLKVPDNVDYIEAAMVEPSAVVAHGFYKSNIQPGMTVAVMGCGSIGLLAIQWARIFGAAHIIAIDIDAHKLDIATSLGAHQTINSKEENLEKFIENHYANQIDLAIESSGAKVTIGQILTLPKKGGEVVLLGIPYDDIEIDRVHFEKILRNELTVCGSWNCLSSNFPGKEWTATLHYMKTKDINVKPIISHFLPLEKGPETFDKLVNKKERFDKVMFTIY
>CP020656.1|AUW99570.1|2071055_2071202_+|hypothetical-protein
MVESMLTFMLGPLRQITDFYMEHLLVSNSIVIAGYFATGIFKKKKVVN
>CP020656.1|AUW99569.1|2069998_2071054_+|sorbitol-dehydrogenase
MKALVKTREGHGNLELLDKEVATPLDDKVKIKVHYAGICGTDIHTYEGHYKVNFPVTLGHEFSGEIVEVGADVKDFKVGDRVTSETTFYVCNECEYCESKDYNLCNHRKGIGTQVDGAFTNYVIAREESLHHIPDEVSYQSAAMTEPLACAHHGVSKIQVNSGDVAVVMGPGPIGLLVAQVLKSKGATVVVTGLDNDKVRLDKAEALHMDYVVNLQQTDLKTYINGITDGYGADVVVECSGAVPAARQGLDILRKKGYYSQIGIFKDAEIPFDMEKVIQKEITVVGSRSQKPADWEPSLQLMADGLVNAEALVTKIYDISKWDEAYQHLKSGEGIKALLKPLDLDENEGEN
>CP020656.1|AUW99568.1|2068721_2069981_+|PTS-galactitol-transporter-subunit-IIC
MSYFTDFVRGFLDLGATVILPVVIFLLGLFFRQKIGAAFRSGLTIGVAFVGIFLVIDLLVKNLGPAAQAMVKNLGVSLNVIDVGWPATSSIAWASSVAAFIIPLGIIVNVVLLVTKVTKTMNVDIWNFWHYTFTAAMVYAVSGSIWQALLAAVIFQVICLKVADWTAPMMSEFFDLPGVSIATGSTISYAPGIYLVKLLQKVPGLNKLDADPETIQKRFGAFGESIFVGLILGLGIGVLAGYKPGDIINLGMSMAAVMVLMPRMVKILMEGLMPVSESARTWLNKRFGEREIYIGLDAAVALGHPAVISTALILVPITVLLAVILPGNQVLPFGDLATIPFVVAFIVGAARGNIIHSVIVGTIMIAISLYIATDVAPIFTDMAKGTNVQMPKGSSEISSIDQGGNIVNYLIFKLFSLFN
>CP020656.1|AUW99567.1|2068216_2068495_+|PTS-galactitol-transporter-subunit-IIB
MKQVLVACGAGIATSTVVNNAIEEMAKEHNIKVDIKQIKITEVGPYEDTADLLVTTAMTKKEYKFPVINARNFLTGIGIEETKQQILTELQK
>CP020656.1|AUW99566.1|2067726_2068194_+|PTS-sugar-transporter-subunit-IIA
MGQQLVHKENIMLNLSATDKESVLSQMSEVLFQNGFVKSTFKDAVIDREKEFATGLPTHLCSVAIPHTDVEHINHRTIGVAVLEKEVPFIEMGTLDQQTEVKIVFMLAMDKVDDQLKLLQQLMQIFQSEEKLEQILRTKDETILATLINDYLEYN
>CP020656.1|AUX00241.1|2067085_2067742_+|transcription-antiterminator-BglG
MKYINKESADIDKEINKLMALIERTTTVNDITELRDGLEDFIANYNSISTINGSIVTQNKTLDLADLIPARHVKRMHHVENIVEAIAKASDVLVANHFIDIKYIHEMQQVFDDSYMVIMQNIAIPHAYSEKHVHKTAMSMLILQEPIYMSDGTAIHIIVPIAAVDKVTHLRALLQLRDVAQDNDAIKRIIQSRKNSDVNEILKNYSNKEARENGWDSN
>CP020656.1|AUW99574.1|2077297_2078467_+|CDP-glycerol--glycerophosphate-glycerophosphotransferase
MIKTTIKKLIEHSIYTTFKLLSKLPNKNLIYFESFHGKQYSDNPKALYEYLTEHSDAQLIWGVKKGYEHIFQQHNVPYVTKFSMKWFLAMPRAKAWMINTRTPDWLYKSPRTTYLQTWHGTPLKKIGLDISNVKMLGTNTQNYQDGFKKESQRWDYLVSPNPYSTSIFQHAFHVSRDKILETGYPRNDKLSHKRNDTEYINGIKTRLNIPLDKKVIMYAPTWRDDEAIREGSYQFNVNFDIEALRQALDDDYVILLRMHYLVVTRIDEHDDFVKDVSDYEDISDLYLISDALVTDYSSVMFDFGVLKRPQIFYAYDLDKYGDELRGFYMDYKKELPGPIVENQTALIDALKQIDETTNEYIEARTVFYQKFCSLEDGHASQRICQTIFK
>CP020656.1|AUW99575.1|2078742_2079459_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MKYAGILAGGIGSRMGNVPLPKQFLDLDNKPILIHTLEKFILINDFEKIIIATPQQWMTHTKDTLRKFKISDERIEVIQGGSDRNDTIMNIVKHIESTNGINDDDVIVTHDAVRPFLTHRIIKENIQAALEYGAVDTVIDAIDTIVTSKDNQTIDAIPVRNEMYQGQTPQSFNINLLKESYAQLSDEQKSILSDACKIIVETNKPVRLVKGELYNIKVTTPYDLKVANAIIRGGIADD
>CP020656.1|AUW99576.1|2079451_2080477_+|ribitol-5-phosphate-dehydrogenase
MINQVYQLVAPRQFEVTYNNVDIYSDYVIVRPLYMSICAADQRYYTGSRDENVLSQKLPMSLIHEGVGEVVFDSKGVFNKGTKVVMVPNTPTEKDDVIAENYLKSSYFRSSGHDGFMQDFVLLNHDRAVPLPDDIDLSIISYTELVTVSLHAIRRFEKKSISNKNTFGIWGDGNLGYITAILLRKLYPESKIYVFGKTDYKLSHFSFVDDVFFINKIPEGLTFDHAFECVGGRGSQSAINQMIDYISPEGSIALLGVSEFPVEVNTRLVLEKGLTLIGSSRSGSKDFQDVVDLYIQYPDIVDKLALLKGQEFEIATINDLTEAFEADLSTSWGKTVLKWIM
>CP020656.1|AUW99577.1|2080498_2082187_+|CDP-glycerol--poly(glycerophosphate)-glycerophosphotransferase
MVKSKIYIDKIYWERVQLFVEGHSENLDLEDSNFVLRNLTETRTMKANDVKIDGNQFVCRFNVAILDNGYYLPEDKYLLVNEQELDYIAQLNPDVINDAYQNLKPEQEEEYNELETQNGKINFLLQTYLKEFRKGGISKKTVYTVTPEISSDVNEFVLDVVVTTPEVKSIYIVRKYKELRKYFRKQSFNTRQFIFKAIFNTTKFFHLKKGNTVLFTSDSRPTMSGNFEYIYNEMLRQNLDKKYDIHTVFKANITDRRGIIDKFRLPYLLGKADYIFVDDFHPLIYTVRFRRSQEVIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYVSSETDIPFYAEAFGIKEKNVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKVILFAPTFRGSGHGTAHYPFFKIDFERLARYCEKNNAVVLFKMHPFVKNRLNIADKHKQYFVDVSDFREVNDILFITDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPYESFVPGKIVQSFDALMDALDNEDYEGEKVIPFLDKHFKYQDGRSSERLVRNLFGS
>CP020656.1|AUW99578.1|2082219_2083941_+|glycosyl-transferase-family-2
MMKFSVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTALLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEDQPQWINALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGKLNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHSRNKKHTMYVPLSVNANKQYRFNIMLEDIKAYLPKEKIWDVFLEVQIGTEVFEVRVGNQRNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISMKLKGKNKIILTGLDRGYVFEEGMASVVLKDDMIMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTAHMTYSLK
>CP020656.1|AUW99579.1|2084084_2084759_+|iron-sulfur-cluster-repair-protein-ScdA
MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAASLEKKNVDLNELLQRLNDVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKETYDTFKNGMLEHMQKEDDVDFPKLIKYEQGEVVNDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
>CP020656.1|AUW99580.1|2085018_2086758_+|sensor-histidine-kinase
MLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
>CP020656.1|AUW99581.1|2086760_2087501_+|DNA-binding-response-regulator
MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNSASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPTYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
>CP020656.1|AUW99582.1|2087613_2088057_+|antiholin-like-protein-LrgA
MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
>CP020656.1|AUW99583.1|2088049_2088751_+|antiholin-like-protein-LrgB
MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF

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Crispr_ID: CP020656_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020656_7

2238050-2238183

Orphan

Consensus_repeat	Method
TATTGAAGAAGATACAA	PILER-CR

2 spacers

The CRISPR arrays of CP020656_7

>merge|CP020656|7|2238050-2238183|PILER-CR
TATTGAAGAAGATACAAACAAAGACAAACCTAATTATCAATTCGGTGGACACAACATTGTTGATTTTGAAGAAGATACACTTCCAAAAGTAAGCGGCCAAAATGAAGGTCAACAAACGATTGAAGAAGATACAA

>CP020656|7|1|2238050-2238183|PILER-CR
TATTGAAGAAGATACAA	ACAAAGACAAACCTAATTATCAATTCGGTGGACACAACATTGTTGA
TTTTGAAGAAGATACAC	TTCCAAAAGTAAGCGGCCAAAATGAAGGTCAACAAAC
GATTGAAGAAGATACAA

Protein	Signature genes	Signature genes Name	Protein_function
CP020656.1\|AUX00257.1\|2241698_2242727_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377230
CP020656.1\|AUW99721.1\|2233725_2235084_+\|gluconate-permease	unknown	unknown	gnl\|CDD\|129873
CP020656.1\|AUW99723.1\|2235466_2235568_+\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUW99720.1\|2232055_2233609_+\|gluconate-kinase	unknown	unknown	gnl\|CDD\|130381
CP020656.1\|AUW99719.1\|2231351_2232032_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
CP020656.1\|AUW99718.1\|2230433_2231198_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
CP020656.1\|AUW99724.1\|2238527_2240456_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223562
CP020656.1\|AUW99730.1\|2247231_2248191_+\|carbohydrate-kinase	unknown	unknown	gnl\|CDD\|238572
CP020656.1\|AUW99726.1\|2242786_2243011_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|223502
CP020656.1\|AUW99729.1\|2245750_2247235_+\|sucrose-6-phosphate-hydrolase	unknown	unknown	gnl\|CDD\|224536
CP020656.1\|AUW99732.1\|2249302_2250586_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|225519
CP020656.1\|AUW99717.1\|2229576_2230269_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|225232
CP020656.1\|AUW99715.1\|2226252_2226456_+\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUW99725.1\|2240708_2241344_+\|redox-sensing-transcriptional-repressor-Rex	unknown	unknown	gnl\|CDD\|225221
CP020656.1\|AUW99722.1\|2235115_2235418_+\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUW99727.1\|2243218_2244469_+\|ammonia-permease	unknown	unknown	gnl\|CDD\|223083
CP020656.1\|AUW99716.1\|2228929_2229346_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227213
CP020656.1\|AUW99728.1\|2244651_2245602_+\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380484
CP020656.1\|AUX00256.1\|2226967_2228791_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224208
CP020656.1\|AUW99731.1\|2248567_2249284_-\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|225818

Protein	Function_ID	Function_description	E-value
CP020656.1\|AUX00257.1\|2241698_2242727_+\|hypothetical-protein	gnl\|CDD\|377230	pfam04143, Sulf_transp, Sulphur transport. This is an integral membrane protein. It is predicted to have a function in the transport of sulphur-containing molecules. It contains several conserved glycines and an invariant cysteine that is probably an important functional residue.	6.61351e-117
CP020656.1\|AUW99721.1\|2233725_2235084_+\|gluconate-permease	gnl\|CDD\|129873	TIGR00791, Gluconate_permease, gluconate transporter. This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	2.53789e-168
CP020656.1\|AUW99720.1\|2232055_2233609_+\|gluconate-kinase	gnl\|CDD\|130381	TIGR01314, gntK_FGGY, gluconate kinase, FGGY type. Gluconate is derived from glucose in two steps. This model describes one form of gluconate kinase, belonging to the FGGY family of carbohydrate kinases. Gluconate kinase phosphoryates gluconate for entry into the Entner-Douderoff pathway. [Energy metabolism, Sugars].	0
CP020656.1\|AUW99719.1\|2231351_2232032_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.37112e-42
CP020656.1\|AUW99718.1\|2230433_2231198_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	2.57514e-33
CP020656.1\|AUW99724.1\|2238527_2240456_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
CP020656.1\|AUW99730.1\|2247231_2248191_+\|carbohydrate-kinase	gnl\|CDD\|238572	cd01167, bac_FRK, Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate. This is in contrast to FRKs [or ketohexokinases (KHKs)] from mammalia and halophilic archaebacteria, which phosphorylate fructose to fructose-1-phosphate.	5.97578e-118
CP020656.1\|AUW99726.1\|2242786_2243011_+\|oxidoreductase	gnl\|CDD\|223502	COG0425, SirA, Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones].	1.08825e-20
CP020656.1\|AUW99729.1\|2245750_2247235_+\|sucrose-6-phosphate-hydrolase	gnl\|CDD\|224536	COG1621, SacC, Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism].	0
CP020656.1\|AUW99732.1\|2249302_2250586_-\|ATP-binding-protein	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.49577e-44
CP020656.1\|AUW99717.1\|2229576_2230269_+\|GTP-pyrophosphokinase	gnl\|CDD\|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	5.59791e-85
CP020656.1\|AUW99725.1\|2240708_2241344_+\|redox-sensing-transcriptional-repressor-Rex	gnl\|CDD\|225221	COG2344, COG2344, AT-rich DNA-binding protein [General function prediction only].	2.11486e-113
CP020656.1\|AUW99727.1\|2243218_2244469_+\|ammonia-permease	gnl\|CDD\|223083	COG0004, AmtB, Ammonia permease [Inorganic ion transport and metabolism].	7.30274e-167
CP020656.1\|AUW99716.1\|2228929_2229346_+\|hypothetical-protein	gnl\|CDD\|227213	COG4876, COG4876, Uncharacterized protein conserved in bacteria [Function unknown].	9.39579e-63
CP020656.1\|AUW99728.1\|2244651_2245602_+\|LacI-family-transcriptional-regulator	gnl\|CDD\|380484	cd01542, PBP1_TreR-like, ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators. Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators. The ligand-binding domain of TreR is structurally homologous to the periplasmic sugar-binding domain of ABC-type transporters and both domains contain the type 1 periplasmic binding protein-like fold. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the type 1 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	1.06569e-85
CP020656.1\|AUX00256.1\|2226967_2228791_+\|hypothetical-protein	gnl\|CDD\|224208	COG1289, COG1289, Predicted membrane protein [Function unknown].	4.60097e-89
CP020656.1\|AUW99731.1\|2248567_2249284_-\|DNA-binding-response-regulator	gnl\|CDD\|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	2.92045e-55

>CP020656.1|AUW99723.1|2235466_2235568_+|hypothetical-protein
MLLKTEQYRLAFIKFKKLMNFAFKGRYYSEKQS
>CP020656.1|AUW99722.1|2235115_2235418_+|hypothetical-protein
MQYIALKHVYFYAENRLKYSKSERYKKYIGYFRVMKGVSRHVFVRIVQAIIMKRLVYCFKLDNDEFNLKNKYKKYKSCVTRVSDDLNTIYSYIPNNKIIN
>CP020656.1|AUW99721.1|2233725_2235084_+|gluconate-permease
MFNEIWPLISVVLGIVILLVLIIGFKLNTFISLIITSMITALMLGIPLTKIMETIEKGMGSTLGHIALIFGLGAILGKLLADGGGATRIADTLIQKFGQKHVQWAMLVAAFIVGIALFFEVGLVLLIPLVFTVAKRANVSVLKLGLPMVTALSVTHGFLPPHPGPVVIAKELKANVGDVLLYGMIIAIPVTLIAGPIFNKVAQKMIPSAYTREGDISALGAQKEFTDQEMPGFGMSLLTATLPVILMLVSTITQLVTGHDKPTNLFESIIYMIGTAGTAMLIAVLFAIVTMGLMRKRKMNHIMESVTNAIYPIGMMLLIIGGGGTFKQVLIDGGVGNTIAKMFEGTEMSPILLAWIVAAVLRIALGSATVAAISTTGIVLPLLQSSDVNVALVVLAIGAGSVILSHVNDAGFWMFKEYFGLTVKETFLTWSLLETIISVSGIIFILFISLFV
>CP020656.1|AUW99720.1|2232055_2233609_+|gluconate-kinase
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYVMRESKVNKDDIKFVSFSAQMHSLIAMDQKHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLVKIFWMKHEWQDVFQRTAKFADIKTYIFYHLFDTYIIDYSMASATGMFNLETLDWDVGALELLGISKEMLPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASDGVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAKRLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEVMNETPKMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPFEENVAVYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ
>CP020656.1|AUW99719.1|2231351_2232032_+|GntR-family-transcriptional-regulator
MMYGYPEKWLEGMITGEGIAAELRLGIVNGHIAEGTLLTENQMAKQFNVSRSPIRDAFKLLQQNQLIQLERMGAHVLPFGEQEKKEMYDLRLMLESFAFSRVKNQERLPIVKEMKKQLEMMKVAVKFEDAESFTKHDFEFHETLIKASNHQYLNSFWSHLKPVMMALVLTSMRQRMQQNPQDFERIHHNHQVFIDAVEQYDSQILKEAFHLNFDDVGKDIEGFWLN
>CP020656.1|AUW99718.1|2230433_2231198_+|MerR-family-transcriptional-regulator
MSNYSTGELAKLCNVTTRTIQYYDRKGILKPQGFTEGKRRVYTEQQRQTLELILLLKDLGCALSDIDMLLKGEGTLKTLNTLLTMKQQEINQQVKQQQAVLNKIKNVQYYVNEASTSPITHLKDIEHVMSKSAEMKSIRRNIWISAGIIGIIQYSSIISAILMKNKWPFLIALPFMICYGIGVTFYYQQKVAYLCPNCQHIFSPSLWAVIKAKHTATTRRFECPNCHETHYCIEVPKAHMSTEQLEISRIQHNN
>CP020656.1|AUW99717.1|2229576_2230269_+|GTP-pyrophosphokinase
MYVDRKPSLYLEDLRHDFKNSLSKFENGDEAFDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYKNKAETEKYRDLLKECATEITEVENKLQQIHSEITE
>CP020656.1|AUW99716.1|2228929_2229346_+|hypothetical-protein
MPFTMKGYPEKWKDFEVIKRQKAIEIANAMLKEGYLEKDVVPIAAKKAKDWYRALSKEEIKALEEENFVQFHTATMEKTEVDSEYATTDNEEHIQEQSNQDKSYFDSESIGNQSGGVRQREPLMDGPHPKVVESFKDV
>CP020656.1|AUX00256.1|2226967_2228791_+|hypothetical-protein
MIIPAIIGYLCGNFQFGLLVATGTLAHIYVFKGPSRSKLRTVIICNLAFAICMMLGTLTAKTPLVFGMTLLIVTVIPFYIFTALKIAGPSSTFFIVTFSLPINLPIAPEEALYRGFAILVGGILATMMVLITIVFSKNKAEEQAIQNDFKLISKLLHTYNDKSAFLQVAKTAVDNFKASDKLLITSTSSNDKLSRRFQKLLLLHTSAQGIYSELLELNAKQIRPLPDELIEMMDHIIAQLDNSEENVRYWRKEVTVTEEFQNLFNHILKIDEMVHANEARIAYEADMRKPLYSKRIYQNLTLDSIVFRNTLRYTAIMMIAIFIALMFDFEKAYWIPLSTHTILLGTSTIHAIERGMARGLGTILGVLVLSVILLFSIPTPVAVILMGIAALFTEALVGANYAIAVVFITIQVILMNGLASQNLTINIAFPRVIDVAMGIVIAIIGLFVLGQRTASALLPNVMAEVVRKEATLFHYLFSENQYKDDVYQKNTAMNLSVKLNNMTQVYNAANGELFSDKTLIQNYYPSLFALEEISFMLNRAMANEDRLTINEQLMGEYLATFENIAKHLELNTELEIKILPDLPQYNYIQSAMMNIQHNGFRERDKNV
>CP020656.1|AUW99715.1|2226252_2226456_+|hypothetical-protein
MKENLEKYIRSLPLIGLIISIFLIILYFLIYRVEGNFCVIILYCLLPLFVNTSLYILYVIIFRYFKK
>CP020656.1|AUW99724.1|2238527_2240456_-|ABC-transporter-ATP-binding-protein
MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQMTLNSNATVFEEMSKPFEHIKRMESLIKEETDWLSKHANDYDSDTYKTHMSRYESLSNQFEQLEGYQYESKIKTVLYGLNFSEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYDVALGDVKRYVGNYEEFIQQRDLYYQKRMQEYESQQAEIKRLETFVEKNITRASTSGMAKSRRKILEKMERIDKPMLDAKSANIQFGFDRNTGNDVMHVKNLEIGYQTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGDITFGANLQIGYYDQKQAEFKSSKTILDYVWDQYPLMNEKDIRAVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEGTILFVSHDRYFINQLANKVFDLTIDGGKMYLGDYQYYIEKVEEAEALKAHQEEQSVNVQAHKKSMEQSSYHNQKEQRREQRKLERQISECENEIETLETTILQIDEQLTQPEVYNNPQKANELAIQKQDSEQKLEHAMSKWEELQQKL
>CP020656.1|AUW99725.1|2240708_2241344_+|redox-sensing-transcriptional-repressor-Rex
MSDQVKIPRATLKRLPLYYRFVSSLKSKGIDRVNSKAISDALQIDSATIRRDFSYFGELGKKGYGYNIDSLLDFFKSELSESDMIKIAIVGVGNLGKALLTYNFSIHDDMTITEAFDVKEDVIGQKIGNVIVKDNDELITTLKKEEIDVVILTTPERVAQKVADELVQAGVKGILNFTPGRINTPSDVQVHQIDLGIELQSLLFFMKNYSE
>CP020656.1|AUX00257.1|2241698_2242727_+|hypothetical-protein
MQRTRFCLTGGFRDMYVQKNNKMFYALLIAITIQSIGLLILTATDILQIPAHSFPILGTIIGSFIFGIGIVLAGGCATGTWYRAGEGLIGSWIALVLYAVTAAITKTGILKPVMDKINQPTNVNSDMSQTTGIPFWGLVVILTIITIFLVVRTLNNKKVRVAVPKLKQRYTGIRYYLFEKRYHPFIAAIVIGLIALLAWPMSASTGRNDGLGITTPSANLVHFLITGETKFIDWGVFLVLGIFIGSYIAARGSREFKWRLPDKITIRNSAIGGICMGFGASVAGGCSIGNGLVETATMTWQGWIALASMIVGVWTMSHFIFVRPMKKVQQQSAKVKQQTQIV
>CP020656.1|AUW99726.1|2242786_2243011_+|oxidoreductase
MIHELGTVGMVCPFPLIEAQKKMATLQSGDELKIDFDCTQATEAIPNWAAENGYPVTNYEQIDNASWTITIQKV
>CP020656.1|AUW99727.1|2243218_2244469_+|ammonia-permease
MNLNDTIFMFLCTLLVWLMTPGLSLFYGGLVQSKNALNTVMQSMAAIVLVTFVWITVGFTISFGNGNLWFGNWEYTFLNHVGFATQEDISPHIPFALFMLFQMMFCTIAISILSGSIAEKMKFIPYLLFVVIWTALVYSPVAHWVWGGGWINKLGVLDFAGGTVVHITSGVSGLVLAIMIGKGNKHSESTPHNLIITLIGGIFVWIGWYGFNVGSAFTFDNIAMLAFTNTVISASAGAIGWLILEYIFKKTTSLLGLLLGALAGLVVITPAAGYVTYLSATIMALIGGICCYIVINYIKVKLKYHDALDAFGIHGVGGIIGAVLTAVFQSKKANPDIENGFIYTGDIHIILVQILCVTAVVIFSIVMTFIIAKVIKLITPLSVTEQETNIGLDKIVHGEHAYFEGELNRFNKHIRY
>CP020656.1|AUW99728.1|2244651_2245602_+|LacI-family-transcriptional-regulator
MKNISDIAKLAGVSKSTVSRFLNNGSVSKKTSEKLTRIIAEHDYQPNQFAQSLRARQTHLIGAIIPRMNSYAVDETIKGLAKQCQKYESQLILNYTGLNIEAEIQALETLARSKVDGIVLMATDITERHIEVINKMNVPIVIVGQQHEQLHSIVHDDYKAGQIIGEWIGQQGYQQVEVFSVSEKDIAVGIHRKRGLLDQLAKYQIKPNIHETNFTYVEAQKDVANVLENVEQVDAVVGATDTIALAAYKYYSDKKDVMKPHQIYGFGGDPMTQLVSPSIKTIHYNYFEAGQCAMEEIQQMLKKQDTPYSVTVDVNI
>CP020656.1|AUW99729.1|2245750_2247235_+|sucrose-6-phosphate-hydrolase
MTEWTREERYQRIEDVDTEYFKTLKQQVDQSKFRQQFHIQPETGLLNDPNGLIFYKGKYYVSHQWFPLGAVHGLKYWYNYTSDDLINFKAEGPILNPDTKYDSHGVYSGSAFEYNGHLYYMYTGNHRDNHWQRHASQMIARLKEDGSVEKFPKPVISQQPEGYTSHFRDPKVFKYDEKYYAIIGAQNNDQQGRLLLYNTEDIINWHYLGEINTELDDFGYMWECPDYFNVDNQDVILICPQGIEPKGDQFKNIYQSGYILGKFDIEKLTYEHENFVELDNGFDFYAPQTFLDEKGRRVLIGWMGLPEIEYPTDNEGWAHCLTIPRVLNVENGQLKQRPYPALEKLRHNKETALGYANKFTRKLHPYEGKQYELIIDILDNDATEVYFELRTSKTSSTLIAYNKRENKITLDRSDSGLLPTNVEGTTRSTILDTPLKQLQIFVDTSSIEIFCNDGERVLTSRIFPTEDALGIKTSTESGQVYLQFTKYDLKDEHK
>CP020656.1|AUW99730.1|2247231_2248191_+|carbohydrate-kinase
MRRLFSIGEALIDFIPNVTNANLKDVQTFTKQIGGAPCNVACTVQKLGQQAYMITQLGNDAFGDSIIETISSIGVDVSKVYRTNEANTALAFVSLTEAGERDFSFYRKPSADMLFEPSFVNDIDVNENDVVHFCSVDLVDSPMRDTHYQLITKTLNANGTVVFDPNVRLPLWDNAEDLRQTIHTFLPLAHIVKVSDEELEFITGIHDENEAIQSLFTGNVTVVIYTKGADGAAVYLKNGINHYHSGYKVKPVDTTGAGDAFIGAVISRILATDVLNLTQLFENEGEEILAFSNRVAAIVTTKYGAINSLPTLQEVEQAF
>CP020656.1|AUW99731.1|2248567_2249284_-|DNA-binding-response-regulator
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDPVGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIMFFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI
>CP020656.1|AUW99732.1|2249302_2250586_-|ATP-binding-protein
METINNLAMATFQLVILFTVAKFISFVKFNLRDYFIIVGIIIPTMFLYYFYGSRAVLIPTFSSIIFLFFKLKYYAIVTILVTMIIMYLSNFATVGLFLTLRKYTTDPAILLPLYILSFSSVSLLATYLVRISLKKFKKSYLSLNKTYMIIISFVLFATFAFFYIYSTNTSSNGDSLIPYALVFIGLIIFISVVILIMSLFTLKEMKYKRNQEEIETYYEYTLKIEAINNEMRKFRHDYVNILTTLSEYIREDDMIGLRAYFNKNIVPMKDNLQMNAIKLNGIENLKVREIKGLITAKILRAQEMNIPISIEIPDEVSSINLNMIDLSRSIGIILDNAIEASTEIDDPIIRVAFIESENSVTFIVMNKCADDIPRIHELFQESFSTKGEGRGLGLSTLKEIADNADNVLLDTIIENGFFIQKVEIINN

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Crispr_ID: CP020656_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020656_8

2260355-2260444

Orphan

Consensus_repeat	Method
TGATTGAGAAGTCAGTCGAAAAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020656_8

>merge|CP020656|8|2260355-2260444|CRISPRCasFinder
TGATTGAGAAGTCAGTCGAAAAACTATTGCAAAAGAAAAACGATTATGTATAATAAAGTTATAAATTGATTGAGAAGTCAGTCAAAAACG

>CP020656|8|7|2260355-2260444|CRISPRCasFinder
TGATTGAGAAGTCAGTCGAAAAAC	TATTGCAAAAGAAAAACGATTATGTATAATAAAGTTATAAAT
TGATTGAGAAGTCAGTCAAAAACG

Protein	Signature genes	Signature genes Name	Protein_function
CP020656.1\|AUW99751.1\|2262618_2264319_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227806
CP020656.1\|AUW99748.1\|2261136_2261346_+\|pathogenicity-island-protein	unknown	unknown	unknown
CP020656.1\|AUW99743.1\|2258427_2259600_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
CP020656.1\|AUW99738.1\|2253437_2254034_-\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
CP020656.1\|AUW99745.1\|2260460_2260679_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
CP020656.1\|AUW99735.1\|2251560_2251695_+\|delta-hemolysin	unknown	unknown	gnl\|CDD\|173213
CP020656.1\|AUW99737.1\|2253181_2253271_-\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUW99754.1\|2266183_2266525_+\|pathogenicity-island-protein	unknown	unknown	unknown
CP020656.1\|AUW99753.1\|2265025_2265667_+\|pathogenicity-island-protein	unknown	unknown	gnl\|CDD\|374630
CP020656.1\|AUW99744.1\|2259613_2260288_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
CP020656.1\|AUW99747.1\|2260997_2261144_+\|pathogenicity-island-protein	unknown	unknown	unknown
CP020656.1\|AUW99740.1\|2255464_2256208_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
CP020656.1\|AUW99746.1\|2260683_2261001_+\|excisionase	unknown	unknown	gnl\|CDD\|200128
CP020656.1\|AUW99752.1\|2264648_2265029_+\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUW99741.1\|2256382_2256667_+\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
CP020656.1\|AUW99736.1\|2252291_2253077_-\|carbon-nitrogen-hydrolase	unknown	unknown	gnl\|CDD\|143607
CP020656.1\|AUW99750.1\|2261735_2262605_+\|mobile-element-associated-protein	unknown	unknown	gnl\|CDD\|214926
CP020656.1\|AUW99739.1\|2254259_2255441_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368653
CP020656.1\|AUW99742.1\|2256742_2258359_+\|molecular-chaperone-GroEL	unknown	unknown	gnl\|CDD\|234573
CP020656.1\|AUW99749.1\|2261348_2261669_+\|pathogenicity-island-protein	unknown	unknown	gnl\|CDD\|369323

Protein	Function_ID	Function_description	E-value
CP020656.1\|AUW99751.1\|2262618_2264319_+\|hypothetical-protein	gnl\|CDD\|227806	COG5519, COG5519, Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair].	1.18395e-165
CP020656.1\|AUW99743.1\|2258427_2259600_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	4.71558e-47
CP020656.1\|AUW99738.1\|2253437_2254034_-\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	2.49787e-115
CP020656.1\|AUW99745.1\|2260460_2260679_+\|transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	9.85461e-11
CP020656.1\|AUW99735.1\|2251560_2251695_+\|delta-hemolysin	gnl\|CDD\|173213	PRK14752, PRK14752, delta-lysin family phenol-soluble modulin.	8.25732e-15
CP020656.1\|AUW99753.1\|2265025_2265667_+\|pathogenicity-island-protein	gnl\|CDD\|374630	pfam16560, SAPI, Putative mobile pathogenicity island. SAPI is a family of putative Gram-positive mobile pathogenicity island proteins. SAPIs are responsible for many superantigen-related diseases in humans as they carry two or more superantigens.	1.06227e-111
CP020656.1\|AUW99744.1\|2259613_2260288_-\|transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.58614e-10
CP020656.1\|AUW99740.1\|2255464_2256208_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.67124e-11
CP020656.1\|AUW99746.1\|2260683_2261001_+\|excisionase	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	1.26138e-17
CP020656.1\|AUW99741.1\|2256382_2256667_+\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	5.94304e-45
CP020656.1\|AUW99736.1\|2252291_2253077_-\|carbon-nitrogen-hydrolase	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	9.57254e-127
CP020656.1\|AUW99750.1\|2261735_2262605_+\|mobile-element-associated-protein	gnl\|CDD\|214926	smart00942, PriCT_1, Primase C terminal 1 (PriCT-1). This alpha helical domain is found at the C terminal of primases.	1.21323e-15
CP020656.1\|AUW99739.1\|2254259_2255441_+\|hypothetical-protein	gnl\|CDD\|368653	pfam05887, Trypan_PARP, Procyclic acidic repetitive protein (PARP). This family consists of several Trypanosoma brucei procyclic acidic repetitive protein (PARP) like sequences. The procyclic acidic repetitive protein (parp) genes of Trypanosoma brucei encode a small family of abundant surface proteins whose expression is restricted to the procyclic form of the parasite. They are found at two unlinked loci, parpA and parpB; transcription of both loci is developmentally regulated.	5.3385e-07
CP020656.1\|AUW99742.1\|2256742_2258359_+\|molecular-chaperone-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
CP020656.1\|AUW99749.1\|2261348_2261669_+\|pathogenicity-island-protein	gnl\|CDD\|369323	pfam07342, DUF1474, Protein of unknown function (DUF1474). This family consists of several bacterial proteins of around 100 residues in length. Members of this family seem to be found exclusively in Staphylococcus aureus. The function of this family is unknown.	1.63366e-18

>CP020656.1|AUW99744.1|2259613_2260288_-|transcriptional-regulator
MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRYDAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIENFDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSLSAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKSTTLHKEILQTDSRLSSDIFKEY
>CP020656.1|AUW99743.1|2258427_2259600_-|site-specific-integrase
MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHAEMVERQLRNGDYIAPSTSTFKQVADDWISQYANEVKVSSVRAREKAINHAIERFNNKPIQTINKHEYQRFVNDISAQYSKNYVDSIIASTNMIFKYAYDMKLIRIMPSEGIKRPKKKISVEELEDTEIHKKFLEKDELFQFLEVAKNHHSPQNSFEVFCTLAYTGMRAGELLALKWSDIDFENNTINITKTYYNPNNNKKQFQILTPKTESSIGKISVDPHVIKLLKNYKVDVQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTDITNKQISTHSFRHTHCALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSILMENVSKDLF
>CP020656.1|AUW99742.1|2256742_2258359_+|molecular-chaperone-GroEL
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>CP020656.1|AUW99741.1|2256382_2256667_+|co-chaperone-GroES
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>CP020656.1|AUW99740.1|2255464_2256208_-|CPBP-family-intramembrane-metalloprotease
MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVVSIVLTQIYGGQQVSPNTEKLIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGNRIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>CP020656.1|AUW99739.1|2254259_2255441_+|hypothetical-protein
MSYHWFKKMLLSTSILILSSSSLGLATHTVEAKDNLNGEKPTTNLNHNITSPSVNSEMNNNETGTPHESNQTGNEGTGSNSRDANPDSNNVKPDSNNQNPSTDSKPDPNNQNPSPNPKPDPDNPKPKPDPKPDPDKPKPNPDPKPDPDNPKPNPDPKPDPNKPNPNPSPDPDQHGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>CP020656.1|AUW99738.1|2253437_2254034_-|nitroreductase-family-protein
MTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSNEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK
>CP020656.1|AUW99737.1|2253181_2253271_-|hypothetical-protein
MLEPTPTCIVCRNWCSNFSMLGPHQLLSI
>CP020656.1|AUW99736.1|2252291_2253077_-|carbon-nitrogen-hydrolase
MKVQIYQLPIIFGDSSKNEAQITQWFEKNMNAEVDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNNQIFNTAFSVNKSGQLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESSDILTVDLNLNEVEQQRENIPVFKSIKLDLYK
>CP020656.1|AUW99735.1|2251560_2251695_+|delta-hemolysin
MSCLILRIFILIKEGVISMAQDIISTIGDLVKWIIDTVNKFTKK
>CP020656.1|AUW99745.1|2260460_2260679_+|transcriptional-regulator
MTILANTRKFKEAMFLKGFNLSDLSRETGVGISYLSQIINGKKIPSPKLAKKMAEVLQVEVNELFEFEVKEA
>CP020656.1|AUW99746.1|2260683_2261001_+|excisionase
MFNINIDEDEARELLEQAINARVDELAKEKYFMTYKELANYLNLSKPTIEELLINNGMKYYMVGSTYRFKKSDVDEFMEQLTAHMNIQNNDFKQVNIKKLLEARQ
>CP020656.1|AUW99747.1|2260997_2261144_+|pathogenicity-island-protein
MKIYLTYICLVSLLTILLLAISNMYVAFSVYAWLITLGCNLTGGLENE
>CP020656.1|AUW99748.1|2261136_2261346_+|pathogenicity-island-protein
MNNEQKEVIEHLVYQLELSVMNNLESYEHTEYVNGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE
>CP020656.1|AUW99749.1|2261348_2261669_+|pathogenicity-island-protein
MNWEIKDLMCDIEVIKQKINDVATKHAWFVEDRFVKNELETKREHINFSASYLEHRIQNEHTVELLQVYLKEFDELIQKFHEIEKASSDVSLATESDDAKKLKITE
>CP020656.1|AUW99750.1|2261735_2262605_+|mobile-element-associated-protein
MNEIKLEYDTHVSVVHYESLDSRSFKSFSKPEWSKLVNKLSVPIEANYKYARGVAVYGDIKDGANDHGETIKKHRNDVNVIYRDVIVLDYDEINDLKQLHEAISSVLSSVAWYWHTSFSHTTEQARIRLYIPLNERISADDYRKYTKVLANKIGHKVDEGSYQPSRCFALPVIQKGHIFIKRVNDCPIMNVDMLEQWSKEFEQSNASPNVIGYTRRDSEYWRELCFGTTEGNRNNALASLIGHLLRCHVNDYIVYSFALLWGQFACKPPMKEQEINATFQSILNKHYNN
>CP020656.1|AUW99751.1|2262618_2264319_+|hypothetical-protein
METGKSDVLDKIEKINKKDSALQEIIPKGYEIEHHQCGVALYQLIPSKKEGEPDKKVFITNTIPQITERFEDIESNEVSFNMLFYDNKTPVNIAVSAEEISDSRQLLKLVNKKLDVTSSTSTKLVDYINVSKRYNPPLNVKVATRLGHVKGYFIYPYQEVMKDSNIKLFSNDKGFQKLIDSFQSKGTLEGYSKKVFGQIKDLPMVMVMLYASLGSVLLREFGLQPFIVEISGSTSTGKTFTLNLVSSVWGTSDLITTWSSTQNSIESMASFLNSFPMFKDDTRNTHPKFVTSATYNFSSGESKSRSNINLTLNAKKEWRNILISTGESSIANMADEKAGVSARVVTLQDQPYPDNFDFTTLDKSFRENYGTLGLAFIKQYESKKDVYKNAFESYQRYFNQKGSNEIMQRLGRAFALLQVTGEVLNDIDGFEHDHFKIIEQTYDSMVKNNKTIDKPKQLLEELLQYLDANRNNIAGDGYSSVKNGDTKAIYKRDYLCILGQTVYDKLGHEMQTITGQWDKKGYLITSKDRIQKEVRFNSQKNRGYAIKDEIIKELGFDFSNSHNPYN
>CP020656.1|AUW99752.1|2264648_2265029_+|hypothetical-protein
MDKEQLKIYIYDYVKEYKEIPIYQLEDLFKEINHDYIGRTSITHDKDENVVFWSGWNKITMFALIELVKSEQLDLVYRGSFVMRYLLDGRVPNLPLAICYPEDGQQTDVLSWVPMVLRINKEEKIK
>CP020656.1|AUW99753.1|2265025_2265667_+|pathogenicity-island-protein
MNIETIVNEFETRAGTLLRYYTGLLEHSKVQPCCFKLYNDPFDMVYVVMNNKLFGHVYIKDCKVRKSFELASPKHTEGLIRSIEGHYVGYELHDGKQLSISDMMASQLFEDEYFMYGLQTYVESNNSDVFEYLENGFDTDTLEGIQSSNTDVIANIEMLYQLATGINEPARELAEGLKLVTEFVQDENATQEDYKALERKLNDLKASYYSLSK
>CP020656.1|AUW99754.1|2266183_2266525_+|pathogenicity-island-protein
MQSIAEKETYHLPTEHLQVFNVIKNTSNKYITKTKILNQLGYEYNSSNERWLRRVINSLVYDYGYPIGCSYKPSERGYYIITTEQEKKQAMRSIKKLADGSMKRYEALKRIEV

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Crispr_ID: CP020656_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020656_9

2335009-2335098

Orphan

Consensus_repeat	Method
AAAAGAAATTCTACAGGCAATGCAAGTTGGGG	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of CP020656_9

>merge|CP020656|9|2335009-2335098|CRISPRCasFinder
AAAAGAAATTCTACAGGCAATGCAAGTTGGGGTGTGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGGCAATGCAAGTTGGGG

>CP020656|9|8|2335009-2335098|CRISPRCasFinder
AAAAGAAATTCTACAGGCAATGCAAGTTGGGG	TGTGGGCCCCAACACAGAGAATTTCG
AAAAGAAATTCTACAGGCAATGCAAGTTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
CP020656.1\|AUW99822.1\|2336607_2337309_+\|transporter	unknown	unknown	gnl\|CDD\|227100
CP020656.1\|AUW99818.1\|2332792_2332903_+\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUW99816.1\|2330660_2331974_+\|UDP-N-acetylmuramate--alanine-ligase	unknown	unknown	gnl\|CDD\|223840
CP020656.1\|AUW99817.1\|2331975_2332707_+\|glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
CP020656.1\|AUW99814.1\|2329694_2329787_+\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUW99821.1\|2336206_2336593_+\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUW99825.1\|2339079_2340297_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224214
CP020656.1\|AUW99815.1\|2329868_2330369_-\|non-heme-ferritin	unknown	unknown	gnl\|CDD\|224445
CP020656.1\|AUW99820.1\|2335231_2335990_+\|methionine-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
CP020656.1\|AUW99826.1\|2340574_2340850_-\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUW99827.1\|2340856_2341321_-\|protein-tyrosine-phosphatase	unknown	unknown	gnl\|CDD\|319971
CP020656.1\|AUX00260.1\|2341467_2341668_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227177
CP020656.1\|AUW99824.1\|2338338_2338968_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|225107
CP020656.1\|AUW99811.1\|2327009_2327540_+\|permease	unknown	unknown	gnl\|CDD\|378690
CP020656.1\|AUX00259.1\|2332931_2333345_+\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUW99813.1\|2328924_2329479_-\|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
CP020656.1\|AUW99828.1\|2341670_2342927_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723
CP020656.1\|AUW99812.1\|2327786_2328857_+\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
CP020656.1\|AUW99819.1\|2333716_2334703_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226614
CP020656.1\|AUW99823.1\|2337305_2338349_+\|two-component-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951

Protein	Function_ID	Function_description	E-value
CP020656.1\|AUW99822.1\|2336607_2337309_+\|transporter	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
CP020656.1\|AUW99813.1\|2328924_2329479_-\|DNA-polymerase-III-subunit-epsilon	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	3.15947e-75
CP020656.1\|AUW99816.1\|2330660_2331974_+\|UDP-N-acetylmuramate--alanine-ligase	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	3.37755e-99
CP020656.1\|AUW99817.1\|2331975_2332707_+\|glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	3.33663e-121
CP020656.1\|AUW99825.1\|2339079_2340297_-\|hypothetical-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	2.45634e-85
CP020656.1\|AUW99820.1\|2335231_2335990_+\|methionine-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126
CP020656.1\|AUW99827.1\|2340856_2341321_-\|protein-tyrosine-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
CP020656.1\|AUX00260.1\|2341467_2341668_+\|hypothetical-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	9.24488e-25
CP020656.1\|AUW99824.1\|2338338_2338968_+\|DNA-binding-response-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.75115e-79
CP020656.1\|AUW99811.1\|2327009_2327540_+\|permease	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.92343e-11
CP020656.1\|AUW99815.1\|2329868_2330369_-\|non-heme-ferritin	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
CP020656.1\|AUW99828.1\|2341670_2342927_+\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
CP020656.1\|AUW99812.1\|2327786_2328857_+\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
CP020656.1\|AUW99819.1\|2333716_2334703_-\|hypothetical-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.20478e-76
CP020656.1\|AUW99823.1\|2337305_2338349_+\|two-component-sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72

>CP020656.1|AUW99819.1|2333716_2334703_-|hypothetical-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>CP020656.1|AUX00259.1|2332931_2333345_+|hypothetical-protein
MKPTKVILRDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEVKFEFALFDSDMDNLKHMDYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVAKSDFTKFINELASLH
>CP020656.1|AUW99818.1|2332792_2332903_+|hypothetical-protein
MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT
>CP020656.1|AUW99817.1|2331975_2332707_+|glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
>CP020656.1|AUW99816.1|2330660_2331974_+|UDP-N-acetylmuramate--alanine-ligase
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYSVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>CP020656.1|AUW99815.1|2329868_2330369_-|non-heme-ferritin
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>CP020656.1|AUW99814.1|2329694_2329787_+|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>CP020656.1|AUW99813.1|2328924_2329479_-|DNA-polymerase-III-subunit-epsilon
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYKNLTYVTNIYGKNLKDKG
>CP020656.1|AUW99812.1|2327786_2328857_+|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGLTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>CP020656.1|AUW99811.1|2327009_2327540_+|permease
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLFLLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ
>CP020656.1|AUW99820.1|2335231_2335990_+|methionine-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>CP020656.1|AUW99821.1|2336206_2336593_+|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>CP020656.1|AUW99822.1|2336607_2337309_+|transporter
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>CP020656.1|AUW99823.1|2337305_2338349_+|two-component-sensor-histidine-kinase
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>CP020656.1|AUW99824.1|2338338_2338968_+|DNA-binding-response-regulator
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>CP020656.1|AUW99825.1|2339079_2340297_-|hypothetical-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIVFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDNNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>CP020656.1|AUW99826.1|2340574_2340850_-|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>CP020656.1|AUW99827.1|2340856_2341321_-|protein-tyrosine-phosphatase
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>CP020656.1|AUX00260.1|2341467_2341668_+|hypothetical-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHD
>CP020656.1|AUW99828.1|2341670_2342927_+|aminopeptidase
MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHELKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAEKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF

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Crispr_ID: CP020656_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020656_10

2659024-2659113

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of CP020656_10

>merge|CP020656|10|2659024-2659113|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTCAACTTTAGTTGTTAGGGGCTTCT

>CP020656|10|9|2659024-2659113|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTT	ATGCAGTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTT
CAACTTTAGTTGTTAGGGGCTTCT

Protein	Signature genes	Signature genes Name	Protein_function
CP020656.1\|AUX00123.1\|2654156_2655095_-\|mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
CP020656.1\|AUX00119.1\|2650337_2650781_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
CP020656.1\|AUX00127.1\|2657915_2659007_+\|transcriptional-regulator	unknown	unknown	unknown
CP020656.1\|AUX00132.1\|2661048_2661906_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
CP020656.1\|AUX00121.1\|2651850_2653224_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
CP020656.1\|AUX00122.1\|2653895_2654126_-\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUX00129.1\|2659985_2660168_-\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUX00134.1\|2662987_2664793_-\|glutamine--fructose-6-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|234729
CP020656.1\|AUX00135.1\|2665473_2667012_+\|PTS-mannitol-transporter-subunit-IICBA	unknown	unknown	gnl\|CDD\|225123
CP020656.1\|AUX00136.1\|2667046_2669179_+\|PTS-lactose-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|226234
CP020656.1\|AUX00125.1\|2656347_2656668_+\|transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
CP020656.1\|AUX00131.1\|2660826_2660919_+\|erm-Leader-peptide	unknown	unknown	unknown
CP020656.1\|AUX00133.1\|2661973_2662756_-\|iron-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
CP020656.1\|AUX00130.1\|2660232_2660391_+\|integrase	unknown	unknown	unknown
CP020656.1\|AUX00118.1\|2649506_2650217_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
CP020656.1\|AUX00128.1\|2659448_2659553_-\|hypothetical-protein	unknown	unknown	unknown
CP020656.1\|AUX00124.1\|2655530_2656196_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|187554
CP020656.1\|AUX00137.1\|2669190_2669625_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014
CP020656.1\|AUX00126.1\|2656669_2657650_+\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
CP020656.1\|AUX00120.1\|2650980_2651394_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225556

Protein	Function_ID	Function_description	E-value
CP020656.1\|AUX00123.1\|2654156_2655095_-\|mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
CP020656.1\|AUX00119.1\|2650337_2650781_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
CP020656.1\|AUX00132.1\|2661048_2661906_-\|HAD-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	5.00207e-59
CP020656.1\|AUX00121.1\|2651850_2653224_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
CP020656.1\|AUX00135.1\|2665473_2667012_+\|PTS-mannitol-transporter-subunit-IICBA	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
CP020656.1\|AUX00136.1\|2667046_2669179_+\|PTS-lactose-transporter-subunit-IIB	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.17174e-68
CP020656.1\|AUX00125.1\|2656347_2656668_+\|transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
CP020656.1\|AUX00133.1\|2661973_2662756_-\|iron-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	8.27306e-106
CP020656.1\|AUX00120.1\|2650980_2651394_-\|hypothetical-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
CP020656.1\|AUX00118.1\|2649506_2650217_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
CP020656.1\|AUX00124.1\|2655530_2656196_-\|oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.27122e-47
CP020656.1\|AUX00137.1\|2669190_2669625_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
CP020656.1\|AUX00126.1\|2656669_2657650_+\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.20197e-108
CP020656.1\|AUX00134.1\|2662987_2664793_-\|glutamine--fructose-6-phosphate-aminotransferase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0

>CP020656.1|AUX00127.1|2657915_2659007_+|transcriptional-regulator
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKETTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>CP020656.1|AUX00126.1|2656669_2657650_+|cation-transporter
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHAH
>CP020656.1|AUX00125.1|2656347_2656668_+|transcriptional-regulator
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>CP020656.1|AUX00124.1|2655530_2656196_-|oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>CP020656.1|AUX00123.1|2654156_2655095_-|mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>CP020656.1|AUX00122.1|2653895_2654126_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>CP020656.1|AUX00121.1|2651850_2653224_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>CP020656.1|AUX00120.1|2650980_2651394_-|hypothetical-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>CP020656.1|AUX00119.1|2650337_2650781_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>CP020656.1|AUX00118.1|2649506_2650217_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>CP020656.1|AUX00128.1|2659448_2659553_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>CP020656.1|AUX00129.1|2659985_2660168_-|hypothetical-protein
MIIFRFKVNAFFPVKLCLMIRFCLESCCIFRRHLLITFHNIRSKFIMFKYISSKCIICTG
>CP020656.1|AUX00130.1|2660232_2660391_+|integrase
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>CP020656.1|AUX00131.1|2660826_2660919_+|erm-Leader-peptide
MTYGSIVAILCALFVIFFIPYMEKKDKKKK
>CP020656.1|AUX00132.1|2661048_2661906_-|HAD-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITTFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIEHFGIHQDETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>CP020656.1|AUX00133.1|2661973_2662756_-|iron-ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDEEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPMLAMIYVTHFIEEITSNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>CP020656.1|AUX00134.1|2662987_2664793_-|glutamine--fructose-6-phosphate-aminotransferase
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>CP020656.1|AUX00135.1|2665473_2667012_+|PTS-mannitol-transporter-subunit-IICBA
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGANQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDNPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>CP020656.1|AUX00136.1|2667046_2669179_+|PTS-lactose-transporter-subunit-IIB
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>CP020656.1|AUX00137.1|2669190_2669625_+|mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	435174-435204	0	1.0
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	523575-523605	0	1.0
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	1012448-1012478	0	1.0
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	1017882-1017912	0	1.0
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	1299069-1299099	0	1.0
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	1501962-1501992	0	1.0
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	1968206-1968236	0	1.0
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	1968264-1968294	0	1.0
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	2333596-2333626	0	1.0
CP020656_9	9.1\|2335041\|26\|CP020656\|CRISPRCasFinder	2335041-2335066	26	CP020656.1	1968249-1968274	0	1.0
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	3828-3858	1	0.968
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	733399-733429	1	0.968
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	733571-733601	1	0.968
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	1502020-1502050	1	0.968
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	1862334-1862364	1	0.968
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	2205879-2205909	1	0.968
CP020656_2	2.1\|700956\|29\|CP020656\|CRISPRCasFinder	700956-700984	29	CP020656.1	284477-284505	1	0.966
CP020656_2	2.1\|700956\|29\|CP020656\|CRISPRCasFinder	700956-700984	29	CP020656.1	1005310-1005338	1	0.966
CP020656_2	2.1\|700956\|29\|CP020656\|CRISPRCasFinder	700956-700984	29	CP020656.1	1012519-1012547	1	0.966
CP020656_2	2.1\|700956\|29\|CP020656\|CRISPRCasFinder	700956-700984	29	CP020656.1	2324320-2324348	1	0.966
CP020656_2	2.1\|700956\|29\|CP020656\|CRISPRCasFinder	700956-700984	29	CP020656.1	2334954-2334982	1	0.966
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	435168-435192	1	0.96
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	523587-523611	1	0.96
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	1012442-1012466	1	0.96
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	1017876-1017900	1	0.96
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	1299081-1299105	1	0.96
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	1501956-1501980	1	0.96
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	1502014-1502038	1	0.96
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	1862346-1862370	1	0.96
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	1968200-1968224	1	0.96
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	1968258-1968282	1	0.96
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	2333590-2333614	1	0.96
CP020656_9	9.1\|2335041\|26\|CP020656\|CRISPRCasFinder	2335041-2335066	26	CP020656.1	1502005-1502030	1	0.962
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	200712-200742	2	0.935
CP020656_1	1.1\|99841\|31\|CP020656\|CRISPRCasFinder	99841-99871	31	CP020656.1	200822-200852	2	0.935
CP020656_2	2.1\|700956\|29\|CP020656\|CRISPRCasFinder	700956-700984	29	CP020656.1	878795-878823	2	0.931
CP020656_4	4.1\|878834\|33\|CP020656\|CRISPRCasFinder	878834-878866	33	CP020656.1	2324277-2324309	2	0.939
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	3840-3864	2	0.92
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	200706-200730	2	0.92
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	200816-200840	2	0.92
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	439602-439626	2	0.92
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	733411-733435	2	0.92
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	733583-733607	2	0.92
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	823362-823386	2	0.92
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	2092038-2092062	2	0.92
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	2205873-2205897	2	0.92
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	CP020656.1	2685972-2685996	2	0.92

1. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 435174-435204, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgcctgtagaatttcttttcgaaattctct	Protospacer
*******************************

2. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 523575-523605, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgcctgtagaatttcttttcgaaattctct	Protospacer
*******************************

3. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 1012448-1012478, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgcctgtagaatttcttttcgaaattctct	Protospacer
*******************************

4. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 1017882-1017912, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgcctgtagaatttcttttcgaaattctct	Protospacer
*******************************

5. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 1299069-1299099, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgcctgtagaatttcttttcgaaattctct	Protospacer
*******************************

6. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 1501962-1501992, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgcctgtagaatttcttttcgaaattctct	Protospacer
*******************************

7. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 1968206-1968236, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgcctgtagaatttcttttcgaaattctct	Protospacer
*******************************

8. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 1968264-1968294, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgcctgtagaatttcttttcgaaattctct	Protospacer
*******************************

9. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 2333596-2333626, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgcctgtagaatttcttttcgaaattctct	Protospacer
*******************************

10. spacer 9.1|2335041|26|CP020656|CRISPRCasFinder matches to position: 1968249-1968274, mismatch: 0, identity: 1.0

tgtgggccccaacacagagaatttcg	CRISPR spacer
tgtgggccccaacacagagaatttcg	Protospacer
**************************

11. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 3828-3858, mismatch: 1, identity: 0.968

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgcctgtagaatttcttttagaaattctct	Protospacer
******************** **********

12. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 733399-733429, mismatch: 1, identity: 0.968

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgcctgtagaatttctttacgaaattctct	Protospacer
******************* ***********

13. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 733571-733601, mismatch: 1, identity: 0.968

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgcctgtagaatttctttacgaaattctct	Protospacer
******************* ***********

14. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 1502020-1502050, mismatch: 1, identity: 0.968

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgtctgtagaatttcttttcgaaattctct	Protospacer
***.***************************

15. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 1862334-1862364, mismatch: 1, identity: 0.968

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgcttgtagaatttcttttcgaaattctct	Protospacer
****.**************************

16. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 2205879-2205909, mismatch: 1, identity: 0.968

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgcctgtagaatttcatttcgaaattctct	Protospacer
**************** **************

17. spacer 2.1|700956|29|CP020656|CRISPRCasFinder matches to position: 284477-284505, mismatch: 1, identity: 0.966

accccaacttgcacattatagtaagctga	CRISPR spacer
accccaacttgcacattattgtaagctga	Protospacer
******************* *********

18. spacer 2.1|700956|29|CP020656|CRISPRCasFinder matches to position: 1005310-1005338, mismatch: 1, identity: 0.966

accccaacttgcacattatagtaagctga	CRISPR spacer
accccaacttgcacattattgtaagctga	Protospacer
******************* *********

19. spacer 2.1|700956|29|CP020656|CRISPRCasFinder matches to position: 1012519-1012547, mismatch: 1, identity: 0.966

accccaacttgcacattatagtaagctga	CRISPR spacer
accccaacttgcacattatcgtaagctga	Protospacer
******************* *********

20. spacer 2.1|700956|29|CP020656|CRISPRCasFinder matches to position: 2324320-2324348, mismatch: 1, identity: 0.966

accccaacttgcacattatagtaagctga	CRISPR spacer
accccaacttgcacattattgtaagctga	Protospacer
******************* *********

21. spacer 2.1|700956|29|CP020656|CRISPRCasFinder matches to position: 2334954-2334982, mismatch: 1, identity: 0.966

accccaacttgcacattatagtaagctga	CRISPR spacer
accccaacttgcacattattgtaagctga	Protospacer
******************* *********

22. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 435168-435192, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

23. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 523587-523611, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

24. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 1012442-1012466, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

25. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 1017876-1017900, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

26. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 1299081-1299105, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

27. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 1501956-1501980, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

28. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 1502014-1502038, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

29. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 1862346-1862370, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctatgttg	Protospacer
******************* *****

30. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 1968200-1968224, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

31. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 1968258-1968282, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

32. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 2333590-2333614, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

33. spacer 9.1|2335041|26|CP020656|CRISPRCasFinder matches to position: 1502005-1502030, mismatch: 1, identity: 0.962

tgtgggccccaacacagagaatttcg	CRISPR spacer
tgtggaccccaacacagagaatttcg	Protospacer
*****.********************

34. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 200712-200742, mismatch: 2, identity: 0.935

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgtctgtagaatttctttttgaaattctct	Protospacer
***.****************.**********

35. spacer 1.1|99841|31|CP020656|CRISPRCasFinder matches to position: 200822-200852, mismatch: 2, identity: 0.935

ttgcctgtagaatttcttttcgaaattctct	CRISPR spacer
ttgtctgtagaatttctttttgaaattctct	Protospacer
***.****************.**********

36. spacer 2.1|700956|29|CP020656|CRISPRCasFinder matches to position: 878795-878823, mismatch: 2, identity: 0.931

accccaacttgcacattatagtaagctga	CRISPR spacer
accccaacttgcacactattgtaagctga	Protospacer
***************.*** *********

37. spacer 4.1|878834|33|CP020656|CRISPRCasFinder matches to position: 2324277-2324309, mismatch: 2, identity: 0.939

gcctctgtgttggggccccgccaacttgcacat	CRISPR spacer
gcttctatgttggggccccgccaacttgcacat	Protospacer
**.***.**************************

38. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 3840-3864, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttagaaattctctgtgttg	Protospacer
******** ********** *****

39. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 200706-200730, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttctttttgaaattctctgtgttg	Protospacer
********.********** *****

40. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 200816-200840, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttctttttgaaattctctatgttg	Protospacer
********.********** *****

41. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 439602-439626, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttatcgaaattctctgtgttg	Protospacer
****** ************ *****

42. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 733411-733435, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttctttacgaaattctctgtgttg	Protospacer
******* *********** *****

43. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 733583-733607, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttctttacgaaattctctatgttg	Protospacer
******* *********** *****

44. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 823362-823386, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctccatgttg	Protospacer
******************. *****

45. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 2092038-2092062, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctttgtgttg	Protospacer
*****************.* *****

46. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 2205873-2205897, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcatttcgaaattctctgtgttg	Protospacer
**** ************** *****

47. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to position: 2685972-2685996, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttctttacgaaattctctatgttg	Protospacer
******* *********** *****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP020656_6	6.1\|2076819\|25\|CP020656\|CRISPRCasFinder	2076819-2076843	25	LC371242	Escherichia phage EcS1 DNA, complete sequence	15447-15471	2	0.92
CP020656_3	3.1\|821097\|27\|CP020656\|CRISPRCasFinder	821097-821123	27	KM359505	Prochlorococcus phage P-TIM68, complete genome	102710-102736	5	0.815
CP020656_11	11.1\|2671380\|34\|CP020656\|CRISPRCasFinder	2671380-2671413	34	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	23034-23067	8	0.765
CP020656_11	11.1\|2671380\|34\|CP020656\|CRISPRCasFinder	2671380-2671413	34	CP030544	Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence	7567-7600	8	0.765

1. spacer 6.1|2076819|25|CP020656|CRISPRCasFinder matches to LC371242 (Escherichia phage EcS1 DNA, complete sequence) position: , mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttctttacgaaattctttttgttg	Protospacer
******* *********.*******

2. spacer 3.1|821097|27|CP020656|CRISPRCasFinder matches to KM359505 (Prochlorococcus phage P-TIM68, complete genome) position: , mismatch: 5, identity: 0.815

gaatttcgaaaagaaattctacagacc	CRISPR spacer
ctatttccaaaagaaattatacagatc	Protospacer
  ***** ********** ******.*

3. spacer 11.1|2671380|34|CP020656|CRISPRCasFinder matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgcatatctttagctttatagcttttatatgct	Protospacer
******************** *.** .*  **

4. spacer 11.1|2671380|34|CP020656|CRISPRCasFinder matches to CP030544 (Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgaataactttagctttattgttataaacagta	Protospacer
*** *** ****************   *** * .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

29289 : 82395

Streptococcus_phage(28.57%)

protease,bacteriocin,holin,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUW97617.1\|29289_30279_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
AUW97618.1\|30573_30969_+	regulatory protein Spx	NA	NA	NA	NA
AUW97619.1\|31339_32059_+	adaptor protein MecA	NA	NA	NA	NA
AUW97620.1\|32179_33166_+	competence protein CoiA	NA	NA	NA	NA
AUW97621.1\|33213_35022_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	5.5e-47	24.5
AUW97622.1\|35481_36288_-	hypothetical protein	NA	NA	NA	NA
AUW97623.1\|36310_36676_-	globin	NA	NA	NA	NA
AUW97624.1\|36779_37373_-	adenylate cyclase	NA	NA	NA	NA
AUW97625.1\|37558_37906_+	hypothetical protein	NA	NA	NA	NA
AUW97626.1\|37922_38558_+	GTP pyrophosphokinase	NA	NA	NA	NA
AUW97627.1\|38574_39384_+	NAD(+) kinase	NA	NA	NA	NA
AUW97628.1\|39380_40235_+	RNA pseudouridine synthase	NA	NA	NA	NA
AUW97629.1\|40255_41641_+	magnesium transporter	NA	NA	NA	NA
AUW97630.1\|41650_43495_+	sodium:proton antiporter	NA	NA	NA	NA
AUW97631.1\|43772_44543_+	enoyl-ACP reductase	NA	NA	NA	NA
AUW97632.1\|44737_45823_-	AI-2E family transporter	NA	NA	NA	NA
AUW97633.1\|46164_47733_+	sodium:alanine symporter	NA	NA	NA	NA
AUW97634.1\|47877_48636_+	acetylesterase	NA	NA	NA	NA
AUW97635.1\|48829_49339_+	hypothetical protein	NA	NA	NA	NA
AUW97636.1\|49451_50660_-	MFS transporter	NA	NA	NA	NA
AUW97637.1\|50619_51795_-	diglucosyl diacylglycerol synthase	NA	NA	NA	NA
AUW97638.1\|52227_53712_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
AUW97639.1\|53692_53953_+	hypothetical protein	NA	NA	NA	NA
AUW97640.1\|53952_55515_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	1.7e-36	28.2
AUW97641.1\|55816_56620_+	hypothetical protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
AUW97642.1\|56838_59163_+\|protease	serine protease	W5SAB9	Pithovirus	1.6e-11	27.8
AUW97643.1\|59179_60538_+	Ktr system potassium uptake protein D	NA	NA	NA	NA
AUW97644.1\|60676_62188_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
AUW97645.1\|62674_63244_-	competence protein ComK	NA	NA	NA	NA
AUW97646.1\|63453_63672_+	IDEAL domain protein	NA	NA	NA	NA
AUW97647.1\|63752_64739_-	lipoate--protein ligase	NA	NA	NA	NA
AUW97648.1\|64937_65114_+	DUF2187 domain-containing protein	NA	NA	NA	NA
AUW97649.1\|65128_65731_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AUW97650.1\|66000_66108_+\|holin	putative holin-like toxin	NA	NA	NA	NA
AUW97651.1\|66646_66748_+	hypothetical protein	NA	NA	NA	NA
AUX00161.1\|66757_67030_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
AUW97652.1\|67073_69038_+	hypothetical protein	NA	NA	NA	NA
AUW97653.1\|69040_69361_+	hypothetical protein	NA	NA	NA	NA
AUW97654.1\|69357_69999_+\|bacteriocin	bacteriocin ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-19	33.0
AUW97655.1\|70086_70377_-	hypothetical protein	NA	NA	NA	NA
AUW97656.1\|70517_70655_+	poly(glycerol-phosphate) alpha-glucosyltransferase	NA	NA	NA	NA
AUW97657.1\|70743_71100_-	hypothetical protein	NA	NA	NA	NA
AUW97658.1\|72593_72725_-	hypothetical protein	NA	NA	NA	NA
AUW97659.1\|72788_73079_-	hypothetical protein	A0A060AN66	Enterococcus_phage	7.5e-07	38.0
AUW97660.1\|73168_73720_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AUW97661.1\|73771_74710_-	1,4-dihydroxy-2-naphthoate octaprenyltransferase	NA	NA	NA	NA
AUW97662.1\|74860_74965_+	hypothetical protein	NA	NA	NA	NA
AUW97663.1\|75041_76253_+	isochorismate synthase	NA	NA	NA	NA
AUW97664.1\|76239_77913_+	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase	NA	NA	NA	NA
AUW97665.1\|77899_78703_+	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
AUW97666.1\|78695_79517_+	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
AUW97667.1\|79754_80084_-	staphostatin B	NA	NA	NA	NA
AUW97668.1\|80121_81303_-	staphopain B	NA	NA	NA	NA
AUW97669.1\|81384_82395_-\|protease	serine protease	A0A2H4PQP7	Staphylococcus_phage	6.2e-16	32.3

DBSCAN-SWA_2

101424 : 109879

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUX00163.1\|101424_101889_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.5e-20	43.8
AUW97686.1\|101875_103000_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
AUW97687.1\|103003_103708_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
AUW97688.1\|103707_103971_+	phosphoribosylformylglycinamidine synthase	NA	NA	NA	NA
AUW97689.1\|103972_104644_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AUW97690.1\|104636_106826_+	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	1.3e-140	39.7
AUW97691.1\|106804_108289_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
AUW97692.1\|108281_109310_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
AUW97693.1\|109312_109879_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_3

343876 : 400170

Staphylococcus_phage(50.0%)

portal,integrase,terminase,holin,protease,head,tRNA,tail

attL 364033:364070|attR 398764:398801

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUW97915.1\|343876_345421_+\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
AUW97916.1\|345421_345787_+	hypothetical protein	NA	NA	NA	NA
AUW97917.1\|345813_346305_+	energy coupling factor transporter S component ThiW	NA	NA	NA	NA
AUW97918.1\|346607_349226_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	8.5e-41	23.7
AUW97919.1\|349238_351248_+	DNA mismatch repair protein MutL	A0A1B2LRQ5	Wolbachia_phage	2.8e-60	30.7
AUW97920.1\|351253_351796_+	glycerol-3-phosphate responsive antiterminator	NA	NA	NA	NA
AUW97921.1\|352270_353089_+	aquaporin	M1H4F4	Acanthocystis_turfacea_Chlorella_virus	2.4e-26	35.1
AUW97922.1\|353217_354714_+	glycerol kinase	NA	NA	NA	NA
AUW97923.1\|354871_356545_+	aerobic glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
AUW97924.1\|356694_357609_+	lysophospholipase	NA	NA	NA	NA
AUW97925.1\|357626_358562_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
AUW97926.1\|358576_358810_+	RNA-binding protein Hfq	NA	NA	NA	NA
AUW97927.1\|359031_359508_-	glutathione peroxidase	Q70H87	Fowlpox_virus	1.2e-22	38.0
AUW97928.1\|359619_360858_+	GTPase HflX	NA	NA	NA	NA
AUW97929.1\|360876_362115_+	hypothetical protein	NA	NA	NA	NA
AUW97930.1\|362357_362726_+	MerR family transcriptional regulator	NA	NA	NA	NA
AUW97931.1\|362744_364085_+	glutamine synthetase	NA	NA	NA	NA
364033:364070	attL	NA	NA	NA	NA
AUW97932.1\|364224_365352_-\|integrase	site-specific integrase	A0A0C5AN64	Paenibacillus_phage	6.2e-33	31.4
AUW97933.1\|365404_366100_-	hypothetical protein	A0A2H4J5B8	uncultured_Caudovirales_phage	3.6e-07	50.3
AUW97934.1\|366111_366495_-	hypothetical protein	NA	NA	NA	NA
AUW97935.1\|366641_367034_-	transcriptional regulator	A0A2I6PE55	Staphylococcus_phage	1.6e-28	53.6
AUW97936.1\|367201_367420_+	DUF739 domain-containing protein	A0A2I6PE94	Staphylococcus_phage	4.9e-19	62.5
AUW97937.1\|367446_367722_+	hypothetical protein	NA	NA	NA	NA
AUW97938.1\|368145_368352_-	hypothetical protein	A1BTY8	Staphylococcus_virus	3.3e-25	75.0
AUW97939.1\|368412_369096_+	phage repressor protein	A9CR56	Staphylococcus_phage	2.0e-106	85.2
AUW97940.1\|369194_369356_+	DUF1270 domain-containing protein	R4IH12	Staphylococcus_phage	1.1e-12	69.8
AUW97941.1\|369442_369760_+	hypothetical protein	W5RAK4	Staphylococcus_phage	1.6e-39	80.6
AUW97942.1\|369749_370016_+	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	3.0e-18	53.6
AUW97943.1\|370020_370557_+	hypothetical protein	A0A0H3U480	Staphylococcus_phage	1.7e-76	82.5
AUW97944.1\|370557_371337_+	chromosomal replication initiator DnaA	A0A1W6JPW0	Staphylococcus_phage	2.3e-127	88.0
AUX00175.1\|371417_371912_+	single-stranded DNA-binding protein	A7TWM8	Staphylococcus_phage	6.4e-83	94.0
AUW97945.1\|372826_373117_+	hypothetical protein	A0A223LIA9	Staphylococcus_phage	7.2e-18	58.1
AUW97946.1\|373131_373290_+	hypothetical protein	A0A0E3T9L7	Staphylococcus_phage	6.7e-18	90.4
AUW97947.1\|373295_373607_+	hypothetical protein	NA	NA	NA	NA
AUW97948.1\|373599_374130_+	nucleotide pyrophosphohydrolase	A0A1P8VVP1	Streptococcus_phage	2.3e-22	39.1
AUW97949.1\|374364_374829_+	hypothetical protein	C9E2P0	Enterococcus_phage	6.1e-19	42.4
AUW97950.1\|374829_375063_+	hypothetical protein	NA	NA	NA	NA
AUW97951.1\|375105_375594_+	RNA polymerase subunit sigma-70	R9TMH4	Paenibacillus_phage	8.7e-08	28.3
AUW97952.1\|375746_376175_+	HNH endonuclease	A1EAE0	Streptococcus_phage	1.1e-25	45.1
AUW97953.1\|376161_377436_+\|terminase	terminase	Q4ZE37	Staphylococcus_virus	3.2e-195	76.2
AUW97954.1\|377448_378897_+\|portal	phage portal protein	Q4ZE36	Staphylococcus_virus	3.7e-195	69.4
AUX00176.1\|379426_380416_+\|head	head morphogenesis protein	Q4ZE35	Staphylococcus_virus	3.8e-50	68.9
AUW97955.1\|380615_380744_+	hypothetical protein	NA	NA	NA	NA
AUW97956.1\|380710_381289_+	hypothetical protein	Q4ZE34	Staphylococcus_virus	1.9e-09	50.8
AUW97957.1\|382295_382769_+	hypothetical protein	A0A2H4J9T3	uncultured_Caudovirales_phage	9.7e-12	31.6
AUW97958.1\|382784_383111_+\|head,tail	phage head-tail adapter protein	Q4ZE31	Staphylococcus_virus	2.1e-26	56.4
AUW97959.1\|383110_383416_+	hypothetical protein	Q4ZE30	Staphylococcus_virus	6.4e-17	40.6
AUW97960.1\|383416_383767_+	hypothetical protein	H9A0N6	Staphylococcus_phage	9.3e-36	60.0
AUW97961.1\|383776_384172_+	hypothetical protein	H9A0N7	Staphylococcus_phage	1.9e-21	42.3
AUW97962.1\|384183_384783_+\|tail	phage major tail protein, TP901-1 family	H9A0N8	Staphylococcus_phage	7.4e-17	47.5
AUW97963.1\|384844_385189_+\|tail	phage tail protein	A0A1J0MFH0	Staphylococcus_phage	2.9e-34	58.9
AUX00177.1\|385239_385593_+	hypothetical protein	Q4ZE25	Staphylococcus_virus	1.7e-37	72.3
AUW97964.1\|385604_388775_+	hypothetical protein	Q4ZE24	Staphylococcus_virus	1.6e-94	54.5
AUW97965.1\|388789_389725_+\|tail	phage tail protein	A0A1J0MF79	Staphylococcus_phage	2.1e-98	55.9
AUW97966.1\|389733_391419_+	hypothetical protein	Q4ZE19	Staphylococcus_virus	1.4e-108	46.5
AUW97967.1\|391436_392450_+	SGNH/GDSL hydrolase family protein	A0A1J0MFI8	Staphylococcus_phage	6.5e-98	52.6
AUW97968.1\|393877_394267_+\|holin	holin	A0A1S6L1J2	Staphylococcus_phage	6.9e-16	38.2
AUW97969.1\|394331_395237_+	N-acetylmuramoyl-L-alanine amidase	A0A1W6JQL2	Staphylococcus_phage	1.0e-65	50.4
AUW97970.1\|395706_395904_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	3.7e-10	48.4
AUX00178.1\|396124_397060_+\|protease	CAAX protease	A0A059NT88	Lactococcus_phage	5.3e-70	44.0
AUW97971.1\|397507_397924_+	hypothetical protein	NA	NA	NA	NA
AUW97972.1\|398350_398575_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	1.6e-20	75.4
AUW97973.1\|398829_400170_+\|head	phage head morphogenesis protein	A0A1J0MF61	Staphylococcus_phage	5.3e-140	58.7
398764:398801	attR	NA	NA	NA	NA

DBSCAN-SWA_4

672514 : 680844

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUW98215.1\|672514_673300_-	zinc ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.0e-18	28.3
AUW98216.1\|673425_674316_-	endonuclease	A0A2H4UU70	Bodo_saltans_virus	3.4e-26	36.0
AUW98217.1\|674325_675672_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	1.1e-55	34.0
AUW98218.1\|675785_676886_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
AUW98219.1\|676888_677566_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
AUW98220.1\|677696_678803_-	RNA polymerase sigma factor SigA	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
AUW98221.1\|679026_680844_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.6e-54	36.0

DBSCAN-SWA_5

748673 : 757716

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUW98287.1\|748673_749192_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
AUW98288.1\|749213_751487_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.1e-63	29.1
AUW98289.1\|751689_753969_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.4e-31	36.6
AUW98290.1\|754243_754504_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
AUW98291.1\|754522_755662_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
AUW98292.1\|755684_756710_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
AUW98293.1\|756711_757716_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_6

948007 : 998961

Staphylococcus_phage(84.51%)

portal,integrase,terminase,holin,head,tail,capsid

attL 949150:949166|attR 992361:992377

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUW98483.1\|948007_948736_+	DUF5067 domain-containing protein	H9A0X8	Staphylococcus_phage	1.8e-17	36.8
949150:949166	attL	NA	NA	NA	NA
AUW98484.1\|949327_949528_-	hypothetical protein	A0A2H4PQS9	Staphylococcus_phage	3.5e-32	100.0
AUW98485.1\|949541_949748_-	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	9.9e-30	98.5
AUW98486.1\|949722_949878_-	hypothetical protein	NA	NA	NA	NA
AUW98487.1\|950276_951722_-	autolysin	Q08JW9	Staphylococcus_phage	5.7e-289	97.7
AUW98488.1\|951702_952140_-\|holin	phage holin	A7YGY0	Staphylococcus_virus	2.2e-71	97.2
AUW98489.1\|952195_954790_-\|tail	phage tail protein	Q4ZC48	Staphylococcus_virus	1.1e-271	57.0
AUW98490.1\|954802_956677_-	CHAP domain-containing protein	Q4ZBP7	Staphylococcus_phage	0.0e+00	97.8
AUW98491.1\|956813_957113_-	hypothetical protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
AUX00194.1\|957153_957327_-	XkdX family protein	A0A059T7K6	Staphylococcus_phage	1.3e-27	100.0
AUW98492.1\|957330_957708_-	hypothetical protein	Q8LTH7	Staphylococcus_phage	7.3e-55	100.0
AUW98493.1\|957707_959531_-	hypothetical protein	B1H3M3	Staphylococcus_phage	0.0e+00	99.8
AUW98494.1\|959530_961429_-	hypothetical protein	A0A0H3U448	Staphylococcus_phage	0.0e+00	95.1
AUW98495.1\|961441_963328_-	peptidase	A0A059T677	Staphylococcus_phage	0.0e+00	97.8
AUW98496.1\|963338_964280_-\|tail	phage tail protein	A0A059T7K5	Staphylococcus_phage	4.5e-178	98.1
AUW98497.1\|964294_967180_-\|terminase	terminase	M9NRJ5	Staphylococcus_phage	2.3e-310	92.2
AUW98498.1\|967183_967468_-	hypothetical protein	A0A059T626	Staphylococcus_phage	9.8e-44	96.8
AUW98499.1\|967512_968025_-	hypothetical protein	A0A059T5B1	Staphylococcus_phage	1.2e-92	99.4
AUW98500.1\|968091_968649_-\|tail	phage tail protein	A0A059T675	Staphylococcus_phage	4.1e-102	100.0
AUW98501.1\|968649_969075_-	hypothetical protein	Q4ZBQ9	Staphylococcus_phage	2.3e-73	98.6
AUW98502.1\|969087_969501_-	hypothetical protein	A0A0N9BAY5	Staphylococcus_phage	2.0e-74	98.5
AUW98503.1\|969487_969823_-\|head,tail	phage head-tail adapter protein	M9NUJ3	Staphylococcus_phage	1.3e-58	98.2
AUW98504.1\|969834_970185_-\|head,tail	phage head-tail adapter protein	A0A0H3U2R5	Staphylococcus_phage	3.2e-60	99.1
AUW98505.1\|970345_971260_-\|capsid	major capsid protein	A0A059T7K3	Staphylococcus_phage	1.3e-169	99.3
AUW98506.1\|971276_971861_-	hypothetical protein	M9NRJ1	Staphylococcus_phage	9.9e-75	99.5
AUW98507.1\|971964_972198_-	hypothetical protein	M9NUJ2	Staphylococcus_phage	2.5e-37	100.0
AUW98508.1\|972201_973152_-\|head	phage head morphogenesis protein	M9NST7	Staphylococcus_phage	2.3e-177	100.0
AUW98509.1\|973120_974545_-\|portal	phage portal protein	A0A0E3T9I6	Staphylococcus_phage	4.8e-272	100.0
AUW98510.1\|974541_975765_-\|terminase	terminase	A0A0N9BAX9	Staphylococcus_phage	7.5e-242	100.0
AUW98511.1\|975757_976252_-\|terminase	terminase	A0A059T7P8	Staphylococcus_phage	1.1e-74	99.4
AUW98512.1\|976582_977005_-	transcriptional regulator	A0A0F6N3E5	Staphylococcus_phage	2.7e-74	99.3
AUW98513.1\|977028_977175_-	hypothetical protein	B2ZYX7	Staphylococcus_phage	3.7e-15	97.9
AUW98514.1\|977175_977349_-	transcriptional regulator	A0A0H3U4U1	Staphylococcus_phage	1.9e-21	96.5
AUW98515.1\|977345_977741_-	hypothetical protein	M9QX07	Staphylococcus_phage	1.3e-62	94.7
AUW98516.1\|977724_977961_-	hypothetical protein	A0A2I6PEM4	Staphylococcus_phage	2.0e-34	94.9
AUW98517.1\|977953_978241_-	DUF1381 domain-containing protein	Q4ZAB6	Staphylococcus_virus	4.4e-44	96.8
AUW98518.1\|978277_978790_-	dUTP pyrophosphatase	Q4ZDG4	Staphylococcus_virus	2.8e-89	98.8
AUW98519.1\|978782_978977_-	hypothetical protein	M1SVE4	Staphylococcus_phage	1.3e-23	93.4
AUW98520.1\|978939_979194_-	hypothetical protein	A7TWH5	Staphylococcus_phage	6.1e-37	92.9
AUW98521.1\|979186_979576_-	acetyltransferase	I1W604	Staphylococcus_phage	1.4e-69	100.0
AUW98522.1\|979572_979944_-	hypothetical protein	I1W606	Staphylococcus_phage	1.6e-65	100.0
AUW98523.1\|979940_980135_-	hypothetical protein	A0A0E3XCV8	Staphylococcus_phage	2.5e-27	100.0
AUW98524.1\|980131_980536_-	hypothetical protein	A0A0E3T8H9	Staphylococcus_phage	6.0e-71	98.5
AUW98525.1\|980538_980745_-	hypothetical protein	A0A2I6PDB7	Staphylococcus_phage	1.3e-34	100.0
AUW98526.1\|980759_981008_-	hypothetical protein	A0A2I6PDB4	Staphylococcus_phage	2.1e-42	100.0
AUW98527.1\|981007_981262_-	hypothetical protein	A0A2K9VBW1	Staphylococcus_phage	1.6e-42	100.0
AUW98528.1\|981261_981879_-	hypothetical protein	A0A0H3U4U9	Staphylococcus_phage	1.2e-83	99.5
AUW98529.1\|981879_982065_-	hypothetical protein	A0A1X9H0T9	Staphylococcus_phage	6.0e-26	95.1
AUW98530.1\|982069_982474_-	hypothetical protein	A7TWN5	Staphylococcus_phage	7.1e-72	100.0
AUW98531.1\|982484_982706_-	hypothetical protein	A0A0H3U2V4	Staphylococcus_phage	2.2e-35	100.0
AUW98532.1\|982718_982877_-	hypothetical protein	A0A2I6PDX0	Staphylococcus_phage	5.8e-22	96.2
AUW98533.1\|982870_983644_-	DNA replication protein DnaC	A0A2I6PDA0	Staphylococcus_phage	2.7e-144	99.6
AUW98534.1\|983653_984457_-	replication protein	A0A2H4JCF5	uncultured_Caudovirales_phage	1.1e-121	100.0
AUW98535.1\|984428_985121_-	hypothetical protein	Q4ZAZ0	Staphylococcus_virus	2.0e-130	98.3
AUW98536.1\|985133_985685_-	single-stranded DNA-binding protein	Q4ZBM4	Staphylococcus_phage	3.4e-101	100.0
AUW98537.1\|985713_986502_-	chromosomal replication initiator DnaA	Q4ZBM5	Staphylococcus_phage	2.6e-142	100.0
AUW98538.1\|986494_986716_-	hypothetical protein	B2ZYV2	Staphylococcus_phage	3.2e-34	100.0
AUW98539.1\|986725_986986_-	hypothetical protein	A0A068A219	Staphylococcus_phage	8.9e-44	100.0
AUW98540.1\|986990_987293_-	hypothetical protein	A0A0F6N3N3	Staphylococcus_phage	1.2e-47	99.0
AUW98541.1\|987385_987547_-	DUF1270 domain-containing protein	C7F7L3	Staphylococcus_phage	1.9e-20	100.0
AUW98542.1\|987560_987770_-	hypothetical protein	A0A2H4PQR1	Staphylococcus_phage	9.7e-33	100.0
AUW98543.1\|987794_988496_-	phage repressor protein	W5R8M8	Staphylococcus_phage	5.1e-126	98.7
AUX00195.1\|988503_988797_+	hypothetical protein	Q4ZB03	Staphylococcus_virus	1.5e-39	97.6
AUW98544.1\|988966_989212_-	transcriptional regulator	I6T7P7	Staphylococcus_virus	1.3e-28	77.8
AUW98545.1\|989378_989693_+	transcriptional regulator	A0A1W6JP51	Staphylococcus_phage	6.4e-36	72.1
AUW98546.1\|989708_990170_+	toxin	A0A2H4IYT4	uncultured_Caudovirales_phage	4.9e-45	58.9
AUW98547.1\|990190_990682_+	hypothetical protein	M9NSS1	Staphylococcus_phage	3.7e-83	98.2
AUW98548.1\|990685_991189_+	hypothetical protein	A0A059T7N4	Staphylococcus_phage	1.5e-47	98.8
AUW98549.1\|991250_992300_+\|integrase	site-specific integrase	W5R968	Staphylococcus_phage	7.0e-196	99.1
AUW98550.1\|992811_993276_-	SsrA-binding protein	W5RAM5	Staphylococcus_phage	1.5e-81	100.0
992361:992377	attR	NA	NA	NA	NA
AUW98551.1\|993297_995670_-	ribonuclease R	Q0GXV6	Lactococcus_phage	1.3e-93	39.0
AUW98552.1\|995703_996444_-	carboxylesterase	NA	NA	NA	NA
AUW98553.1\|996559_996793_-	protein-export membrane protein SecG	NA	NA	NA	NA
AUW98554.1\|996859_997318_-	hypothetical protein	NA	NA	NA	NA
AUW98555.1\|997656_998961_-	enolase	W6LP63	Streptococcus_phage	6.7e-196	80.7

DBSCAN-SWA_7

1047183 : 1061044

uncultured_Caudovirales_phage(55.56%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUW98601.1\|1047183_1048140_-	iron ABC transporter permease	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
AUX00197.1\|1048126_1049098_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
AUW98602.1\|1049136_1049292_-	hypothetical protein	NA	NA	NA	NA
AUW98603.1\|1049512_1049617_-	hypothetical protein	NA	NA	NA	NA
AUW98604.1\|1049749_1050721_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
AUW98605.1\|1050838_1052944_-	ribonucleotide-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
AUW98606.1\|1052906_1053305_-	protein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
AUW98607.1\|1053454_1053721_-	ribonucleoside-diphosphate reductase	NA	NA	NA	NA
AUW98608.1\|1054105_1054972_+	EamA family transporter	NA	NA	NA	NA
AUW98609.1\|1054991_1055492_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
AUW98610.1\|1055521_1055767_+	hypothetical protein	NA	NA	NA	NA
AUW98611.1\|1055832_1057338_+	MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
AUW98612.1\|1057415_1057517_-	hypothetical protein	NA	NA	NA	NA
AUW98613.1\|1057607_1058525_+	lipid kinase	A0A1V0SBJ0	Catovirus	3.7e-07	22.0
AUW98614.1\|1058958_1059051_+	hypothetical protein	NA	NA	NA	NA
AUW98615.1\|1059148_1059691_-	5'(3')-deoxyribonucleotidase	NA	NA	NA	NA
AUW98616.1\|1059838_1059964_-	hypothetical protein	NA	NA	NA	NA
AUW98617.1\|1059985_1061044_-	histidinol-phosphate transaminase	A0A0H3TLT9	Faustovirus	1.1e-20	27.3

DBSCAN-SWA_8

1073016 : 1080835

Pandoravirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUW98627.1\|1073016_1074168_-	aminodeoxychorismate synthase component I	S4VNU7	Pandoravirus	1.2e-23	36.1
AUW98628.1\|1074151_1074745_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
AUW98629.1\|1075095_1075764_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
AUW98630.1\|1075765_1076185_+	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
AUW98631.1\|1076188_1076902_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
AUW98632.1\|1077000_1077585_+	hypothetical protein	NA	NA	NA	NA
AUW98633.1\|1077864_1078305_+	hypothetical protein	NA	NA	NA	NA
AUW98634.1\|1078645_1079119_+	DoxX family protein	NA	NA	NA	NA
AUW98635.1\|1079093_1079780_+	DNA-binding response regulator	NA	NA	NA	NA
AUW98636.1\|1079779_1080835_+	two-component sensor histidine kinase	A0A1V0SGX0	Hokovirus	1.6e-14	29.5

DBSCAN-SWA_9

2256382 : 2270204

Staphylococcus_phage(72.22%)

integrase,terminase,coat

attL 2258342:2258361|attR 2271125:2271144

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUW99741.1\|2256382_2256667_+	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
AUW99742.1\|2256742_2258359_+	molecular chaperone GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
2258342:2258361	attL	NA	NA	NA	NA
AUW99743.1\|2258427_2259600_-\|integrase	site-specific integrase	A0A1W6JQD3	Staphylococcus_phage	6.6e-219	97.7
AUW99744.1\|2259613_2260288_-	transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	1.6e-39	45.8
AUW99745.1\|2260460_2260679_+	transcriptional regulator	A0A2H4JB11	uncultured_Caudovirales_phage	1.3e-19	66.7
AUW99746.1\|2260683_2261001_+	excisionase	A0A1W6JQE0	Staphylococcus_phage	1.6e-50	97.1
AUW99747.1\|2260997_2261144_+	pathogenicity island protein	NA	NA	NA	NA
AUW99748.1\|2261136_2261346_+	pathogenicity island protein	Q4ZE76	Staphylococcus_phage	1.7e-29	94.2
AUW99749.1\|2261348_2261669_+	pathogenicity island protein	A0A1W6JQH0	Staphylococcus_phage	6.5e-20	58.2
AUW99750.1\|2261735_2262605_+	mobile element-associated protein	Q4ZE74	Staphylococcus_phage	1.5e-164	96.2
AUW99751.1\|2262618_2264319_+	hypothetical protein	Q4ZE73	Staphylococcus_phage	1.3e-308	95.2
AUW99752.1\|2264648_2265029_+	hypothetical protein	Q4ZE71	Staphylococcus_phage	3.2e-66	96.0
AUW99753.1\|2265025_2265667_+	pathogenicity island protein	Q4ZE67	Staphylococcus_phage	1.4e-109	92.0
AUW99754.1\|2266183_2266525_+	pathogenicity island protein	Q4ZE66	Staphylococcus_phage	1.1e-57	99.1
AUW99755.1\|2266555_2267209_+	hypothetical protein	Q4ZE82	Staphylococcus_phage	2.7e-113	98.2
AUW99756.1\|2267261_2267789_+\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	2.9e-89	97.7
AUX00258.1\|2267920_2268133_+	pathogenicity island family protein	Q4ZE86	Staphylococcus_phage	1.1e-31	98.6
AUW99757.1\|2268129_2268699_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.7e-100	97.4
AUW99758.1\|2268853_2269558_-	toxin	NA	NA	NA	NA
AUW99759.1\|2269967_2270204_+	DUF3102 domain-containing protein	A0A2H4JAH5	uncultured_Caudovirales_phage	8.7e-14	48.1
2271125:2271144	attR	NA	NA	NA	NA

DBSCAN-SWA_10

2418871 : 2453374

Staphylococcus_phage(90.62%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUW99898.1\|2418871_2419624_-	hypothetical protein	A0A097PAT7	Streptococcus_pyogenes_phage	4.4e-51	47.2
AUW99899.1\|2419650_2420421_-	exotoxin	A0EX09	Staphylococcus_phage	4.3e-25	33.5
AUW99900.1\|2420420_2421047_-	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	3.9e-93	93.8
AUW99901.1\|2421120_2422116_-	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	4.2e-73	97.2
AUW99902.1\|2422196_2422847_-	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	3.0e-56	99.1
AUX00262.1\|2423149_2423605_+	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	1.2e-78	98.6
AUW99903.1\|2423763_2425242_+	2-succinylbenzoate-CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.5e-289	100.0
AUW99904.1\|2425246_2426248_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	9.7e-187	98.2
AUW99905.1\|2426244_2426502_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	3.6e-45	98.8
AUW99906.1\|2426567_2427041_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.7e-83	98.1
AUX00263.1\|2427045_2427792_+	dipeptidyl aminopeptidase	A0A2H4PQM6	Staphylococcus_phage	2.2e-143	99.2
AUW99907.1\|2428169_2429762_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
AUW99908.1\|2430133_2431327_+	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
AUW99909.1\|2431451_2432360_+	hypothetical protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
AUW99910.1\|2432571_2433405_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	7.8e-158	99.3
AUW99911.1\|2433416_2433596_-	hypothetical protein	NA	NA	NA	NA
AUW99912.1\|2433787_2434141_-	camphor resistance protein CrcB	A0A2H4PQQ7	Staphylococcus_phage	2.6e-22	100.0
AUW99913.1\|2434137_2434503_-	camphor resistance protein CrcB	A0A2H4PQR0	Staphylococcus_phage	1.4e-58	99.2
AUW99914.1\|2434758_2435061_-	hypothetical protein	NA	NA	NA	NA
AUW99915.1\|2435320_2436034_+	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
AUW99916.1\|2436473_2437109_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AUW99917.1\|2437404_2437848_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
AUW99918.1\|2437834_2438278_-	competence protein ComK	NA	NA	NA	NA
AUW99919.1\|2438390_2438861_-	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
AUW99920.1\|2439059_2439284_+	hypothetical protein	NA	NA	NA	NA
AUW99921.1\|2439559_2440414_+	autolysin	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
AUW99922.1\|2440708_2441104_-	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	1.8e-72	99.2
AUW99923.1\|2441121_2442414_-	arsenical efflux pump membrane protein ArsB	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
AUW99924.1\|2442413_2442728_-	transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	9.8e-53	98.1
AUW99925.1\|2443250_2444753_+	pyridine nucleotide-disulfide oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
AUX00264.1\|2445245_2446277_+	riboflavin biosynthesis protein RibD	A0A2H4PQS8	Staphylococcus_phage	2.0e-195	98.8
AUW99926.1\|2446283_2446916_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	3.4e-113	100.0
AUW99927.1\|2446926_2448108_+	riboflavin biosynthesis protein RibBA	A0A2H4PQS2	Staphylococcus_phage	1.7e-227	100.0
AUW99928.1\|2448120_2448585_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.5e-70	100.0
AUW99929.1\|2448706_2449708_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	3.1e-185	100.0
AUX00265.1\|2449616_2449808_+	hypothetical protein	NA	NA	NA	NA
AUW99930.1\|2449819_2449939_+	hypothetical protein	NA	NA	NA	NA
AUW99931.1\|2449941_2450769_+	lysophospholipase	NA	NA	NA	NA
AUW99932.1\|2451339_2451741_+	MarR family transcriptional regulator	NA	NA	NA	NA
AUW99933.1\|2451860_2452424_-	16S rRNA (cytosine(1402)-N(4))-methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
AUW99934.1\|2452420_2453374_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP020656

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection