CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
CP026475	Escherichia coli strain KBN10P04869 plasmid pKBN10P04869B, complete sequence	0 crisprs	cas14j	0	0	2
CP026473	Escherichia coli strain KBN10P04869 chromosome, complete genome	9 crisprs	RT,csa3,PD-DExK,cas3,cas7,cas5,cas6e,cas1,cas2,DEDDh,c2c9_V-U4,DinG	1	21	8
CP026476	Escherichia coli strain KBN10P04869 plasmid pKBN10P04869C, complete sequence	0 crisprs	NA	0	0	1
CP026474	Escherichia coli strain KBN10P04869 plasmid pKBN10P04869A, complete sequence	0 crisprs	NA	0	0	2

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

839 : 32261

Escherichia_phage(65.52%)

tail,plate

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUY31548.1\|839_2858_-	DNA adenine methylase	Q1MVI4	Enterobacteria_phage	0.0e+00	95.2
AUY31549.1\|2854_3760_-	Recombination-associated protein RdgC	A0A077SK17	Escherichia_phage	1.6e-159	99.7
AUY31550.1\|3752_4037_-	hypothetical protein	Q71TA2	Escherichia_phage	3.5e-49	100.0
AUY31551.1\|4499_5288_+	hypothetical protein	A0A1B0V830	Salmonella_phage	7.3e-121	99.6
AUY31552.1\|5327_5750_+	hypothetical protein	A0A1B0VCB0	Salmonella_phage	2.7e-58	100.0
AUY31553.1\|5927_6320_+	hypothetical protein	A0A077SLJ1	Escherichia_phage	2.0e-71	99.2
AUY31554.1\|6637_7498_+	Replication protein RepA	Q71TL8	Escherichia_phage	4.7e-158	100.0
AUY31555.1\|7410_7983_-	hypothetical protein	NA	NA	NA	NA
AUY31556.1\|8055_9252_+	Chromosome partitioning protein ParA	A0A077SL49	Escherichia_phage	1.1e-224	99.7
AUY31557.1\|9268_10270_+	Chromosome partitioning protein ParB	Q38420	Escherichia_phage	1.7e-178	100.0
AUY31558.1\|10495_12202_+	hypothetical protein	Q1MVJ5	Enterobacteria_phage	6.3e-311	94.2
AUY31559.1\|12262_13852_+	hypothetical protein	Q71TB2	Escherichia_phage	2.4e-304	99.2
AUY31560.1\|13861_14677_+	hypothetical protein	Q1MVJ7	Enterobacteria_phage	1.1e-111	98.5
AUY31561.1\|15305_15815_+\|plate	Baseplate protein	Q1MVJ9	Enterobacteria_phage	1.3e-91	100.0
AUY31562.1\|15956_16583_+	hypothetical protein	A0A1B0VBK8	Salmonella_phage	4.0e-114	99.5
AUY31563.1\|16918_18088_-	Transposase	A0A077SLN2	Escherichia_phage	2.4e-205	99.5
AUY31564.1\|18245_19055_-	Replication protein repL	Q1MVK3	Enterobacteria_phage	3.3e-145	98.9
AUY31565.1\|19120_19921_-	host killing protein	Q1MVK4	Enterobacteria_phage	3.5e-147	99.2
AUY31566.1\|20085_21129_-	antirepressor	Q71TN2	Escherichia_phage	1.9e-185	97.7
AUY31567.1\|21125_21347_-	Cell division protein	Q38557	Escherichia_phage	8.1e-38	97.3
AUY31568.1\|21926_22244_+	hypothetical protein	Q71TC5	Escherichia_phage	2.9e-28	100.0
AUY31569.1\|22251_23031_+	hypothetical protein	Q71TC6	Escherichia_phage	2.7e-144	96.1
AUY31570.1\|23240_23807_+	hypothetical protein	Q71TN7	Escherichia_phage	9.5e-99	98.4
AUY31571.1\|23817_24429_+\|tail	Major tail tube protein	Q71TN8	Escherichia_phage	2.9e-109	99.5
AUY31572.1\|24443_25325_+	phage morphogenetic protein PmgB	A0A1B0VBL3	Salmonella_phage	1.8e-173	99.3
AUY31573.1\|25406_29126_+	Transglycosylase	Q71TP0	Escherichia_phage	0.0e+00	87.9
AUY31574.1\|29125_29482_+	hypothetical protein	Q71TP1	Escherichia_phage	1.0e-61	100.0
AUY31575.1\|29478_30912_+	bleomycin hydrolase	Q71TP2	Escherichia_phage	3.4e-270	99.4
AUY31576.1\|30911_31748_+	Tail tube protein	A0A077SLH5	Escherichia_phage	1.5e-153	99.6
AUY31577.1\|31826_32261_+	Tail fiber protein R	Q71TD4	Escherichia_phage	3.7e-74	98.6

DBSCAN-SWA_2

36661 : 103982

Escherichia_phage(59.65%)

tail,lysis,plate,head,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUY31579.1\|36661_36943_+	LydC	Q71TD9	Escherichia_phage	8.7e-45	97.8
AUY31580.1\|37010_37340_+	Holin	Q37876	Escherichia_phage	1.3e-52	100.0
AUY31581.1\|37336_37780_+\|lysis	lysis protein	A0A077SK09	Escherichia_phage	1.3e-82	100.0
AUY31582.1\|37766_38369_+	OdaE	Q1MVM6	Enterobacteria_phage	1.6e-99	99.5
AUY31583.1\|38370_40290_+	phage protein DarA	A0A1B0V7H1	Salmonella_phage	0.0e+00	98.6
AUY31584.1\|40286_40652_+	DdrA	Q1MVM8	Enterobacteria_phage	1.5e-44	96.7
AUY31585.1\|40664_43652_+	Putative ddrB	A0A1B0VFX4	Salmonella_phage	0.0e+00	99.3
AUY31586.1\|43641_43959_+	Repressor	Q1MVN0	Enterobacteria_phage	1.9e-43	86.7
AUY31587.1\|43989_44778_-	hypothetical protein	Q71TF1	Escherichia_phage	2.4e-140	95.0
AUY31588.1\|44784_45462_-	hypothetical protein	A0A1B0VBT1	Salmonella_phage	7.9e-124	96.9
AUY31589.1\|45968_46790_+	hypothetical protein	NA	NA	NA	NA
AUY31590.1\|47328_52092_-	hypothetical protein	NA	NA	NA	NA
AUY31591.1\|52579_54613_-	Integrase	NA	NA	NA	NA
AUY31592.1\|54629_56168_-	hypothetical protein	NA	NA	NA	NA
AUY31593.1\|56154_57423_-	Integrase	NA	NA	NA	NA
AUY31594.1\|57560_58049_-	Single-stranded DNA-binding protein	A0A1B0VAF5	Salmonella_phage	5.5e-87	98.8
AUY31595.1\|58131_58776_+	Lysozyme	A0A1B0V7G8	Salmonella_phage	4.4e-124	99.1
AUY31596.1\|59067_60087_-\|head	head processing protein	Q71TR6	Escherichia_phage	1.2e-184	99.7
AUY31597.1\|60079_61789_-	hypothetical protein	Q71TR7	Escherichia_phage	0.0e+00	99.5
AUY31598.1\|61865_68633_+	helicase	Q1MVN7	Enterobacteria_phage	0.0e+00	98.4
AUY31599.1\|68666_69107_+	hypothetical protein	A0A077SLF0	Escherichia_phage	1.7e-79	100.0
AUY31600.1\|69103_69352_+	hypothetical protein	Q71TG0	Escherichia_phage	1.8e-41	100.0
AUY31601.1\|69393_70698_-	hypothetical protein	Q38324	Lactococcus_phage	1.2e-06	30.4
AUY31602.1\|70754_71396_-	hypothetical protein	A0A077SK30	Escherichia_phage	8.2e-115	99.1
AUY31603.1\|71583_72144_-	Recombination enhancement function protein	Q5QBN4	Enterobacteria_phage	4.2e-99	97.8
AUY31604.1\|72753_73785_-	recombinase	A0A077SLE7	Escherichia_phage	1.9e-193	99.1
AUY31605.1\|73792_74014_-	hypothetical protein	A0A077SLI9	Escherichia_phage	3.4e-36	100.0
AUY31606.1\|74617_74827_+	hypothetical protein	Q5XLQ8	Enterobacteria_phage	4.8e-32	100.0
AUY31607.1\|74937_75789_+	hypothetical protein	A0A077SLM8	Escherichia_phage	6.1e-158	99.6
AUY31608.1\|75813_77298_-\|terminase	Large terminase protein	Q71T61	Escherichia_phage	1.5e-292	100.0
AUY31609.1\|77297_78491_-	Terminase A protein	Q5QBP3	Enterobacteria_phage	7.2e-181	88.7
AUY31610.1\|78576_79029_-	Late promoter-activating protein	Q71T63	Escherichia_phage	3.0e-79	100.0
AUY31611.1\|79117_80161_-	hypothetical protein	Q1MVE3	Enterobacteria_phage	1.8e-207	99.7
AUY31612.1\|80372_80753_-	death-on-curing family protein	Q71T66	Escherichia_phage	1.9e-63	100.0
AUY31613.1\|80752_80974_-	prevent-host-death family protein	A0A222YXU1	Escherichia_phage	6.7e-32	100.0
AUY31614.1\|81046_81436_-	DNA repair protein	Q1MVE7	Enterobacteria_phage	8.3e-70	100.0
AUY31615.1\|81610_82195_+	hypothetical protein	Q1MVE8	Enterobacteria_phage	2.8e-109	97.9
AUY31616.1\|83403_83541_+	hypothetical protein	NA	NA	NA	NA
AUY31617.1\|83616_83979_-	PmgV	A0A1B0VBR1	Salmonella_phage	9.8e-57	100.0
AUY31618.1\|83975_84908_-	hypothetical protein	A0A1B0VDS6	Salmonella_phage	4.5e-178	97.7
AUY31619.1\|84889_85264_-	hypothetical protein	A0A077SL57	Escherichia_phage	4.9e-67	96.8
AUY31620.1\|85270_85564_-	hypothetical protein	A0A077SK23	Escherichia_phage	3.1e-45	92.8
AUY31621.1\|86058_86943_-	phage protein	Q1MVF7	Enterobacteria_phage	6.9e-120	97.7
AUY31622.1\|87990_88488_-	hypothetical protein	A0A2D1GLY5	Escherichia_phage	2.4e-45	61.1
AUY31623.1\|88484_88724_-	hypothetical protein	S5MQM0	Escherichia_phage	2.0e-34	92.4
AUY31624.1\|88716_88920_-	hypothetical protein	A0A2R2Z313	Escherichia_phage	6.8e-31	94.0
AUY31625.1\|89003_89732_-	hypothetical protein	Q71T76	Escherichia_phage	2.4e-139	98.7
AUY31626.1\|89926_90433_-	Putative kinase-phosphatase	A0A1B0VAK0	Salmonella_phage	4.8e-94	100.0
AUY31627.1\|90505_91768_-	hypothetical protein	A0A1B0V7L1	Salmonella_phage	5.4e-235	100.0
AUY31628.1\|91769_91988_-	hypothetical protein	Q71TI9	Escherichia_phage	3.4e-36	100.0
AUY31629.1\|92069_92771_-	hypothetical protein	Q1MVG6	Enterobacteria_phage	4.2e-144	100.0
AUY31630.1\|92767_93445_-	Serine/threonine-protein phosphatase	A0A077SLQ6	Escherichia_phage	7.6e-135	100.0
AUY31631.1\|93441_94068_-	PmgP	Q71T82	Escherichia_phage	6.1e-123	100.0
AUY31632.1\|94791_95370_-	norphogenetic protein	Q71T85	Escherichia_phage	7.4e-107	99.0
AUY31633.1\|95372_95618_-	hypothetical protein	Q71T86	Escherichia_phage	6.2e-39	98.8
AUY31634.1\|96151_97369_+\|tail	Phage tail protein	A0A077SL53	Escherichia_phage	1.1e-224	100.0
AUY31635.1\|97372_98101_+\|tail	Phage tail protein	A0A077SK19	Escherichia_phage	9.3e-139	100.0
AUY31636.1\|98087_98873_+\|plate	Baseplate protein	Q71T90	Escherichia_phage	4.6e-144	99.6
AUY31637.1\|98874_99891_+\|tail	putative tail length determination protein	A0A077SLQ1	Escherichia_phage	3.5e-192	100.0
AUY31638.1\|99883_100516_+\|plate	Baseplate protein	Q71TK2	Escherichia_phage	6.9e-90	100.0
AUY31639.1\|100562_101561_-	hypothetical protein	Q71TK3	Escherichia_phage	3.8e-191	97.0
AUY31640.1\|101560_102925_-	DNA helicase	A0A1B0VG30	Salmonella_phage	1.1e-252	99.8
AUY31641.1\|103556_103982_-	tellurite/colicin resistance protein	Q71TK7	Escherichia_phage	1.8e-70	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP026473

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CRISPR-Cas detection and classification

Crispr_ID: CP026473_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026473_1

635714-635853

Orphan

Consensus_repeat	Method
TTTGTATCGTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026473_1

>merge|CP026473|1|635714-635853|CRISPRCasFinder
TTTGTATCGTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCAACAGCAGTCGGATGCGGCGTAAACACCTTATCTGACCTACGTTTTGTGTCGTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCA

>CP026473|1|1|635714-635853|CRISPRCasFinder
TTTGTATCGTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCA	ACAGCAGTCGGATGCGGCGTAAACACCTTATCTGACCTACGT
TTTGTGTCGTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCA

Protein	Signature genes	Signature genes Name	Protein_function
CP026473.1\|AUY27808.1\|632491_632803_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|178979
CP026473.1\|AUY27805.1\|630279_631275_-\|Protease	unknown	unknown	gnl\|CDD\|223896
CP026473.1\|AUY27803.1\|626817_628062_+\|Tryptophan-specific-transport-protein	unknown	unknown	gnl\|CDD\|182492
CP026473.1\|AUY27806.1\|631483_632008_+\|SCP-2-sterol-transfer-family-protein	unknown	unknown	gnl\|CDD\|225696
CP026473.1\|AUY27818.1\|640418_641510_-\|Fimbrial-protein	unknown	unknown	gnl\|CDD\|366088
CP026473.1\|AUY27815.1\|637061_637457_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|129354
CP026473.1\|AUY27811.1\|633913_634549_+\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187560
CP026473.1\|AUY27822.1\|645798_646590_-\|PTS-system-mannose/fructose/sorbose-family-IID-component	unknown	unknown	gnl\|CDD\|182115
CP026473.1\|AUY27819.1\|641520_643893_-\|Putative-outer-membrane-usher-protein-psac	unknown	unknown	gnl\|CDD\|225729
CP026473.1\|AUY27809.1\|632844_633288_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235127
CP026473.1\|AUY27804.1\|629392_630271_-\|Peptidase-U32-family-protein	unknown	unknown	gnl\|CDD\|237968
CP026473.1\|AUY27812.1\|634621_635662_+\|Membrane-protein	unknown	unknown	gnl\|CDD\|223773
CP026473.1\|AUY27813.1\|635866_636442_-\|Putative-phospholipid-binding-domain-protein	unknown	unknown	gnl\|CDD\|182907
CP026473.1\|AUY27814.1\|636451_637042_-\|DnaA-initiator-associating-protein-DiaA	unknown	unknown	gnl\|CDD\|182811
CP026473.1\|AUY27810.1\|633267_633786_-\|protease-I	unknown	unknown	gnl\|CDD\|153228
CP026473.1\|AUY27821.1\|645042_645744_-\|Glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|182064
CP026473.1\|AUY27820.1\|644022_644238_-\|hypothetical-protein	unknown	unknown	unknown
CP026473.1\|AUY27817.1\|639515_640376_+\|Ribosomal-RNA-small-subunit-methyltransferase-I	unknown	unknown	gnl\|CDD\|184956
CP026473.1\|AUY27807.1\|632001_632505_+\|Putative-N-acetyltransferase-YhbS	unknown	unknown	gnl\|CDD\|225695
CP026473.1\|AUY27816.1\|637414_639451_-\|Penicillin-binding-protein-activator-LpoA	unknown	unknown	gnl\|CDD\|225649

Protein	Function_ID	Function_description	E-value
CP026473.1\|AUY27808.1\|632491_632803_-\|hypothetical-protein	gnl\|CDD\|178979	PRK00329, PRK00329, GIY-YIG nuclease superfamily protein; Validated.	8.18979e-46
CP026473.1\|AUY27805.1\|630279_631275_-\|Protease	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	4.87234e-118
CP026473.1\|AUY27803.1\|626817_628062_+\|Tryptophan-specific-transport-protein	gnl\|CDD\|182492	PRK10483, PRK10483, tryptophan permease; Provisional.	0
CP026473.1\|AUY27806.1\|631483_632008_+\|SCP-2-sterol-transfer-family-protein	gnl\|CDD\|225696	COG3154, COG3154, Putative lipid carrier protein [Lipid metabolism].	8.79126e-85
CP026473.1\|AUY27818.1\|640418_641510_-\|Fimbrial-protein	gnl\|CDD\|366088	pfam00419, Fimbrial, Fimbrial protein.	3.34626e-21
CP026473.1\|AUY27815.1\|637061_637457_-\|hypothetical-protein	gnl\|CDD\|129354	TIGR00252, UPF0102_protein_HI_1656, TIGR00252 family protein. the scores for Mycobacterium tuberculosis and Treponema pallidum are low considering the alignment [Hypothetical proteins, Conserved].	3.92681e-63
CP026473.1\|AUY27811.1\|633913_634549_+\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187560	cd05250, CC3_like_SDR_a, CC3(TIP30)-like, atypical (a) SDRs. Atypical SDRs in this subgroup include CC3 (also known as TIP30) which is implicated in tumor suppression. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine rich NAD(P)-binding motif that resembles the extended SDRs, and have an active site triad of the SDRs (YXXXK and upstream Ser), although the upstream Asn of the usual SDR active site is substituted with Asp. For CC3, the Tyr of the triad is displaced compared to the usual SDRs and the protein is monomeric, both these observations suggest that the usual SDR catalytic activity is not present. NADP appears to serve an important role as a ligand, and may be important in the interaction with other macromolecules. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.89133e-65
CP026473.1\|AUY27822.1\|645798_646590_-\|PTS-system-mannose/fructose/sorbose-family-IID-component	gnl\|CDD\|182115	PRK09855, PRK09855, PTS N-acetylgalactosamine transporter subunit IID.	5.05026e-179
CP026473.1\|AUY27819.1\|641520_643893_-\|Putative-outer-membrane-usher-protein-psac	gnl\|CDD\|225729	COG3188, FimD, P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion].	0
CP026473.1\|AUY27809.1\|632844_633288_+\|hypothetical-protein	gnl\|CDD\|235127	PRK03467, PRK03467, hypothetical protein; Provisional.	2.19601e-100
CP026473.1\|AUY27804.1\|629392_630271_-\|Peptidase-U32-family-protein	gnl\|CDD\|237968	PRK15447, PRK15447, putative protease; Provisional.	0
CP026473.1\|AUY27812.1\|634621_635662_+\|Membrane-protein	gnl\|CDD\|223773	COG0701, COG0701, Predicted permeases [General function prediction only].	4.11883e-63
CP026473.1\|AUY27813.1\|635866_636442_-\|Putative-phospholipid-binding-domain-protein	gnl\|CDD\|182907	PRK11023, PRK11023, divisome-associated lipoprotein YraP.	1.97056e-117
CP026473.1\|AUY27814.1\|636451_637042_-\|DnaA-initiator-associating-protein-DiaA	gnl\|CDD\|182811	PRK10886, PRK10886, DnaA initiator-associating protein DiaA; Provisional.	5.61903e-143
CP026473.1\|AUY27810.1\|633267_633786_-\|protease-I	gnl\|CDD\|153228	cd03134, GATase1_PfpI_like, A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. This group includes proteins similar to PfpI from P. furiosus. and PH1704 from Pyrococcus horikoshii. These enzymes are ATP-independent intracellular proteases and may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. For PH1704, it is believed that this Cys together with a different His in one monomer and Glu (from an adjacent monomer) forms a different catalytic triad from the typical GATase1domain. PfpI is homooligomeric. Protease activity is only found for oligomeric forms of PH1704.	6.06977e-86
CP026473.1\|AUY27821.1\|645042_645744_-\|Glucosamine-6-phosphate-deaminase	gnl\|CDD\|182064	PRK09762, PRK09762, galactosamine-6-phosphate isomerase; Provisional.	2.71242e-147
CP026473.1\|AUY27817.1\|639515_640376_+\|Ribosomal-RNA-small-subunit-methyltransferase-I	gnl\|CDD\|184956	PRK14994, PRK14994, SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional.	0
CP026473.1\|AUY27807.1\|632001_632505_+\|Putative-N-acetyltransferase-YhbS	gnl\|CDD\|225695	COG3153, COG3153, Predicted acetyltransferase [General function prediction only].	1.31299e-64
CP026473.1\|AUY27816.1\|637414_639451_-\|Penicillin-binding-protein-activator-LpoA	gnl\|CDD\|225649	COG3107, LppC, Putative lipoprotein [General function prediction only].	6.33924e-141

>CP026473.1|AUY27812.1|634621_635662_+|Membrane-protein
MTGQSSSQAATPIQWWKPALFFLVVIAGLWYVKWEPYYGKAFTAAETHSIGKSILAQADANPWQAALDYAMIYFLAVWKAAVLGVILGSLIQVLIPRDWLLRTLGQSRFRGTLLGTLFSLPGMMCTCCAAPVAAGMRRQQVSMGGALAFWMGNPVLNPATLVFMGFVLSWGFAAIRLVAGLVMVLLIATLVQKWVRETPQTQAPVEIDIPEAQGGFFSRWGRALWTLFWSTIPVYILAVLVLGAARVWLFPHADGTVDNSLMWVVAMAVAGCLFVIPTAAEIPIVQTMMLAGMGTAPALALLMTLPAVSLPSLIMLRKAFPAKALWLTGAMVAVSGVIVGGLALLF
>CP026473.1|AUY27811.1|633913_634549_+|NAD-dependent-epimerase/dehydratase-family-protein
MSQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMPGVFNPHDPQLTDALAQVTDPIDIVFCCLGTTRREAGSKEAFIHADYTLVVDTALTGRRLGAQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNETLFAPLFRLLPGNWKSIDARDVARVMLAESMRPEHEGVTILSSSELRKRAE
>CP026473.1|AUY27810.1|633267_633786_-|protease-I
MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLLGA
>CP026473.1|AUY27809.1|632844_633288_+|hypothetical-protein
METLIAISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFYILTEEKTRHAQMSGPQAAVAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARKAYNRRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRDSGTEQA
>CP026473.1|AUY27808.1|632491_632803_-|hypothetical-protein
MQTMTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKGELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVAEGAGFAELLSSLQTPEIKSD
>CP026473.1|AUY27807.1|632001_632505_+|Putative-N-acetyltransferase-YhbS
MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDGFLTLGLVATDDEGQVIGYVAFSPVDVQGEDLQWVGMAPLAVDEKYRGQGLARQLVYEGLDSLNEFGYAAVVTLGDPALYSRFGFELAAHHDLRCRWPGTESAFQVHRLADDALNGVTGLVEYHEHFNRF
>CP026473.1|AUY27806.1|631483_632008_+|SCP-2-sterol-transfer-family-protein
MLDKLRSRIVHLGPSLLSVPVKLTPFALKRQVLEQVLSWQFRQALDDGELEFLEGRWLSIHVRDIDLQWFTSVVNGKLVVSQNAQADVSFSADASDLLMIAARKQDPDTLFFQRRLVIEGDTELGLYVKNLMDAIELEQMPKALRMMLLQLADFVEAGMKNAPETKQTSVGEPC
>CP026473.1|AUY27805.1|630279_631275_-|Protease
MELLCPAGNLPALKAAIENGADAVYIGLKDDTNARHFAGLNFTEKKLQEAVSFVHQHRRKLHIAINTFAHPDGYARWQRAVDMAAQLGADALILADLAMLEYAAERYPHIERHVSVQASATNEEAINFYHRHFDVARVVLPRVLSIHQVKQLARVTPVPLEVFAFGSLCIMSEGRCYLSSYLTGESPNTVGACSPARFVRWQQTPQGLESRLNEVLIDRYQDGENAGYPTLCKGRYLVDGERYHALEEPTSLNTLELLPELMAANIASVKIEGRQRSPAYVSQVAKVWRQAIDRCKADPQNFVPQSAWMETLGSMSEGTQTTLGAYHRKWQ
>CP026473.1|AUY27804.1|629392_630271_-|Peptidase-U32-family-protein
MKYSLGPVLWYWPKETLEEFYQQAATSSADVIYLGEAVCSKRRATKVGDWLEMAKSLAGSGKQIVLSTLALVQASSELGELKRYVENGEFLIEASDLGVVNMCAERKLPFVAGHALNCYNAVTLKILLKQGMMRWCMPVELSRDWLVNLLNQCDELGIRNQFEVEVLSYGHLPLAYSARCFTARSEDRPKDECETCCIKYPNGRNVLSQENQQVFVLNGIQTMSGYVYNLGNELASMQGLVDVVRLSPQGTDTFAMLDAFRANENGAAPLPLTANSDCNGYWRRLAGLELQA
>CP026473.1|AUY27803.1|626817_628062_+|Tryptophan-specific-transport-protein
MATLTTTQTSPSLLGGVVIIGGTIIGAGMFSLPVVMSGAWFFWSMAALIFTWFCMLHSGLMILEANLNYRIGSSFDTITKDLLGKGWNVVNGISIAFVLYILTYAYISASGSILHHTFAEMSLNVPARAAGFGFALLVAFVVWLSTKAVSRMTAIVLGAKVITFFLTFGSLLGHVQPATLFNVAESNASYAPYLLMTLPFCLASFGYHGNVPSLMKYYGKDPKTIVKCLVYGTLMALALYTIWLLATMGNIPRPEFIGIAEKGGNIDVLVQALSGVLNSRSLDLLLVVFSNFAVASSFLGVTLGLFDYLADLFGFDDSALGRLKTALLTFAPPVVGGLLFPNGFLYAIGYAGLAATIWAAIVPALLARASRKRFGSPKFRVWGGKPMITLILVFGVGNALVHILSSFNLLPVYQ
>CP026473.1|AUY27813.1|635866_636442_-|Putative-phospholipid-binding-domain-protein
MKALSPIAVLISALLLQGCVAAAVVGTAAVGTKAATDPRSVGTQVDDGTLEVRVNSALSKDEQIKKEARINVTAYQGKVLLVGQSPNAELSARAKQIAMGVDGANEVYNEIRQGQPIGLGEASNDTWITTKVRSQLLTSDLVKSSNVKVTTENGEVFLMGLVTEREAKAAADIASRVSGVKRVTTAFTFIK
>CP026473.1|AUY27814.1|636451_637042_-|DnaA-initiator-associating-protein-DiaA
MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDD
>CP026473.1|AUY27815.1|637061_637457_-|hypothetical-protein
MATVPTRSGSPRQLTTKQTGDAWEAQARRWLEGKGLRFIAANVNERGGEIDLIMREGRTTVFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGSFDTVDCRFDVVAFTGNEVEWIKDAFNDHS
>CP026473.1|AUY27816.1|637414_639451_-|Penicillin-binding-protein-activator-LpoA
MVPSTFSRLKAARCLPVVLAALIFAGCGTHTPDQSTAYMQGTAQADSAFYLQQMQQSSDDTRINWQLLAIRALVKEGKTGQAVELFNQLPQELNDSQRREKTLLAVEIKLAQKDFAGAQNLLAKITPADLEQNQQARYWQAKIDASQGRPSIDLLRALIAQEPLLGAKEKQQNIDATWQALSSMTQEQANTLVINADENILQGWLDLQRVWFDNRNDPDMMKAGIADWQKRYPNNPGAKMLPTQLVNVKAFKPASTNKIALLLPLNGQAAVFGRTIQQGFEAAKNIGTQPVAAQVAAAPAADVAEQPQPQTVDGVASPAQASVSDLTGEQPAAQPVPVSAPATSTAAVSAPANPSAELKIYDTSSQPLSQILSQVQQDGASIVVGPLLKNNVEELLKSNTPLNVLALNQPENIENRVNICYFALSPEDEARDAARHIRDQGKQAPLVLIPRSSLGDRVANAFAQEWQKLGGGTVLQQKFGSTSELRAGVNGGSGIALTGSPITPRATTDSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGEIAFIKPMIAMRNGSQSGATLYASSRSAQGTAGPDFRLEMEGLQYSEIPMLAGGNLPLMQQALSAVNNDYSLARMYAMGVDAWSLANHFSQMRQVQGFEINGNTGSLTANPDCVINRKLSWLQYQQGQVVPAS
>CP026473.1|AUY27817.1|639515_640376_+|Ribosomal-RNA-small-subunit-methyltransferase-I
MKQHQSADNSQGQLYIVPTPIGNLADITQRALEVLQAVDLIAAEDTRHTGLLLQHFGINARLFALHDHNEQQKAETLLAKLQEGQNIALVSDAGTPLINDPGYHLVRTCREAGIRVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIEAEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGAPVGELLAWVKEDENRRKGEMVLIVEGHKAQEEDLPADALRTLALLQAELPLKKAAALAAEIHGVKKNALYKYALEQQG
>CP026473.1|AUY27818.1|640418_641510_-|Fimbrial-protein
MKRAPLITGLLLISTSCAYASSGGCGADSTSGATNYSSVVDDVTVNQTDNVTGREFTSATLSSTNWQYACSCSAGKAVKLVYMVSPVLTTTGHQAGYYKLNDSLDIKTTLKANDIPGLVTDQTVSVNTRFTQIKSNTVYSAATQTGVCQGDTSRYGPVNIGANTTFTLYVTKPFLGSMTIPKTDIAVIKGAWVDGMGSPSTGDFHDLVKLSIQGNLTAPQSCKINQGDVIKVNFGFINGQKFTTRNAMPDGFTPVDFDITYDCGDTSKIKNSLQMRIDGTTGVVDQYNLVARRRSSDNAPDVGIRIENLGGGVANIPFQNGILPVDPSGHGTVNMRAWPVNLVGGELETGKFQGTATITVIVR
>CP026473.1|AUY27819.1|641520_643893_-|Putative-outer-membrane-usher-protein-psac
MLETTKSGMQTTDLSRFSKKYAQLPGTYQVDIWLNKKKVSQKKITFTANAEQLLQPQFTVEQLRELGIKVDEIPALAEKDDDSVINSLEQIIPGTAAEFDFNHQRLNLSIPQIALYRDARGYVSPSRWDDGIPTLFTNYSFTGSDNRYRQGNRSQRQYLNMQNGANFGPWRLRNYSTWTRNDQTSSWNTISSYLQRDIKALKSQLLLGESATSGSIFSSYTFTGVQLASDDNMLPNSQRGFAPTVRGIANSSAIVTIRQNGYVIYQSNVPAGAFEINDLYPSSNSGDLEVTIEESDGTQRRFIQPYSSLPMMQRPGHLKYSATAGRYRADANSDSKEPEFAEATAIYGLNNTFTLYSGLLGSEDYYALGIGIGGTLGALGALSMDINRADTQFDNQHSFHGYQWRTQYIKDIPETNTNIAVSYYRYTNDGYFSFDEANTRNWDYNSRQKSEIQFNISQTIFDGVSLYASGSQQDYWGNNEKNRNISVGVSGQQWGIGYSLNYQYSRYTDQNNDRALSLNLSIPLERWLPRSRVSYQMTSQKDRPTQHEMRLDGSLLDDGRLSYSLEQSLDDDNNHNSSVNASYRSPYGTFSAGYSYGNDSSQYNYGVTGGVVIHPHGVTLSQYLGNAFALIDANGASGVRIQNYPGIATDPFGYAVVPYLTTYQENRLSVDTTQLPDNVDLEQTTQFVVPNRGAMVAARFNANIGYRVLVTVSDRNGKPLPFGALASNDETGQQSIVDEGGILYLSGISSKSQSWTVRWGNQADQQCQFAFSTPDSEPTTSVLQGTAQCH
>CP026473.1|AUY27820.1|644022_644238_-|hypothetical-protein
MAENRVEANAHNAGGCPASNAIHGHINDFLVRTGLRSGVSELQLPCFTAVRAEIALMSGGAFAVTHHPVSS
>CP026473.1|AUY27821.1|645042_645744_-|Glucosamine-6-phosphate-deaminase
MQTLQQVENYTALSERASEYLLAVIRSKPDAVICLATGATPLLTYHYLVEKIHQQQVDVSQLTFVKLDEWVDLPLTMPGTCETFLQQHIVQPLGLREDQLISFRSEEINETECERVTNLIARKGGLDLCVLGLGKNGHLGLNEPGESLQPACHISQLDARTQQHEMLKTAGRPVTRGITLGLKDILNAREVLLLVTGEGKQDATERFLTAKVSTAIPASFLWLHSNFICLINT
>CP026473.1|AUY27822.1|645798_646590_-|PTS-system-mannose/fructose/sorbose-family-IID-component
MGSEISKKDITRLGFRSSLLQASFNYERMQAGGFTWAMLPILKKIYKDDKPGLSAAMKDNLEFINTHPNLVGFLMGLLISMEEKGENRDTIKGLKVALFGPIAGIGDAIFWFTLLPIMAGICSSFASQGNLLGPILFFAVYLLIFFLRVGWTHVGYSVGVKAIDKVRENSQMIARSATILGITVIGGLIASYVHINVVTSFAIDSTHSVALQQDFFDKVFPNILPMAYTLLMYYFLRVKKAHPVLLIGVTFVLSIVCSAFGIL

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Crispr_ID: CP026473_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026473_2

677160-677277

Orphan

Consensus_repeat	Method
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026473_2

>merge|CP026473|2|677160-677277|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGGGTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGATGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

>CP026473|2|2|677160-677277|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	GTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGA
TGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

Protein	Signature genes	Signature genes Name	Protein_function
CP026473.1\|AUY27850.1\|676362_677139_+\|Putative-inner-membrane-protein	unknown	unknown	gnl\|CDD\|226206
CP026473.1\|AUY27845.1\|669355_670687_+\|Threonine/serine-transporter-TdcC	unknown	unknown	gnl\|CDD\|184191
CP026473.1\|AUY27843.1\|667307_668246_+\|HTH-type-transcriptional-regulator-TdcA	unknown	unknown	gnl\|CDD\|182391
CP026473.1\|AUY27841.1\|664770_665958_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182043
CP026473.1\|AUY27853.1\|678343_679240_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176122
CP026473.1\|AUY27855.1\|679888_680254_-\|Inner-membrane-protein-YhaH	unknown	unknown	gnl\|CDD\|225694
CP026473.1\|AUY27860.1\|682876_683182_-\|membrane-protein	unknown	unknown	gnl\|CDD\|226941
CP026473.1\|AUY27858.1\|682180_682480_-\|Inner-membrane-protein-YqjK	unknown	unknown	gnl\|CDD\|372871
CP026473.1\|AUY27847.1\|671954_674249_+\|PFL-like-enzyme-TdcE	unknown	unknown	gnl\|CDD\|153087
CP026473.1\|AUY27844.1\|668344_669334_+\|Threonine-dehydratase	unknown	unknown	gnl\|CDD\|236317
CP026473.1\|AUY27842.1\|665979_666519_-\|hypothetical-protein	unknown	unknown	unknown
CP026473.1\|AUY27849.1\|674723_676088_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|185000
CP026473.1\|AUY27848.1\|674262_674652_+\|Protein-tdcF	unknown	unknown	gnl\|CDD\|105214
CP026473.1\|AUY27854.1\|679290_679647_-\|Inner-membrane-protein-YhaI	unknown	unknown	gnl\|CDD\|225694
CP026473.1\|AUY27846.1\|670712_671921_+\|Propionate-kinase	unknown	unknown	gnl\|CDD\|183484
CP026473.1\|AUY27859.1\|682469_682874_-\|Inner-membrane-protein-YqjE	unknown	unknown	gnl\|CDD\|227681
CP026473.1\|AUY27857.1\|681602_682085_-\|Inner-membrane-protein-YqjF	unknown	unknown	gnl\|CDD\|225168
CP026473.1\|AUY27856.1\|680546_681533_-\|S-transferase	unknown	unknown	gnl\|CDD\|223512
CP026473.1\|AUY27851.1\|677350_677515_-\|hypothetical-protein	unknown	unknown	unknown
CP026473.1\|AUY27852.1\|677537_678239_-\|Pirin	unknown	unknown	gnl\|CDD\|224655

Protein	Function_ID	Function_description	E-value
CP026473.1\|AUY27850.1\|676362_677139_+\|Putative-inner-membrane-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	2.21711e-119
CP026473.1\|AUY27845.1\|669355_670687_+\|Threonine/serine-transporter-TdcC	gnl\|CDD\|184191	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional.	0
CP026473.1\|AUY27843.1\|667307_668246_+\|HTH-type-transcriptional-regulator-TdcA	gnl\|CDD\|182391	PRK10341, PRK10341, transcriptional regulator TdcA.	0
CP026473.1\|AUY27841.1\|664770_665958_-\|hypothetical-protein	gnl\|CDD\|182043	PRK09716, PRK09716, YhaC family protein.	0
CP026473.1\|AUY27853.1\|678343_679240_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176122	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold. HupR, a member of the LysR family, activates hupA transcription under low-iron conditions in the presence of hemin. The expression of many iron-uptake genes, such as hupA, is regulated at the transcriptional level by iron and an iron-binding repressor protein called Fur (ferric uptake regulation). Under iron-abundant conditions with heme, the active Fur repressor protein represses transcription of the iron-uptake gene hupA, and prevents transcriptional activation via HupR. Under low-iron conditions with heme, the Fur repressor is inactive and transcription of the hupA is allowed. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.2986e-51
CP026473.1\|AUY27855.1\|679888_680254_-\|Inner-membrane-protein-YhaH	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	3.68376e-42
CP026473.1\|AUY27860.1\|682876_683182_-\|membrane-protein	gnl\|CDD\|226941	COG4575, ElaB, Uncharacterized conserved protein [Function unknown].	1.46625e-41
CP026473.1\|AUY27847.1\|671954_674249_+\|PFL-like-enzyme-TdcE	gnl\|CDD\|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
CP026473.1\|AUY27844.1\|668344_669334_+\|Threonine-dehydratase	gnl\|CDD\|236317	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB.	0
CP026473.1\|AUY27856.1\|680546_681533_-\|S-transferase	gnl\|CDD\|223512	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	0
CP026473.1\|AUY27849.1\|674723_676088_+\|L-serine-ammonia-lyase	gnl\|CDD\|185000	PRK15040, PRK15040, L-serine ammonia-lyase.	0
CP026473.1\|AUY27848.1\|674262_674652_+\|Protein-tdcF	gnl\|CDD\|105214	PRK11401, PRK11401, enamine/imine deaminase.	1.34001e-81
CP026473.1\|AUY27854.1\|679290_679647_-\|Inner-membrane-protein-YhaI	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	1.64644e-35
CP026473.1\|AUY27846.1\|670712_671921_+\|Propionate-kinase	gnl\|CDD\|183484	PRK12379, PRK12379, propionate kinase.	0
CP026473.1\|AUY27859.1\|682469_682874_-\|Inner-membrane-protein-YqjE	gnl\|CDD\|227681	COG5393, COG5393, Predicted membrane protein [Function unknown].	2.73939e-60
CP026473.1\|AUY27857.1\|681602_682085_-\|Inner-membrane-protein-YqjF	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	1.8476e-29
CP026473.1\|AUY27858.1\|682180_682480_-\|Inner-membrane-protein-YqjK	gnl\|CDD\|372871	pfam13997, YqjK, YqjK-like protein. The YqjK-like protein family includes the E. coli YqjK protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 100 amino acids in length. There is a single completely conserved residue R that may be functionally important.	6.11451e-20
CP026473.1\|AUY27852.1\|677537_678239_-\|Pirin	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	1.02982e-67

>CP026473.1|AUY27850.1|676362_677139_+|Putative-inner-membrane-protein
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
>CP026473.1|AUY27849.1|674723_676088_+|L-serine-ammonia-lyase
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLSHDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
>CP026473.1|AUY27848.1|674262_674652_+|Protein-tdcF
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATYPTRSYVQVARLPKDVKLEIEAIAVRSA
>CP026473.1|AUY27847.1|671954_674249_+|PFL-like-enzyme-TdcE
MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGDESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIVGLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPDMLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDLEATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNGGAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSGDPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYAAQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYAINGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDKYSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDGEYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNTPDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKEDPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGYAVRFNALTREQQQDVISRTFTQAL
>CP026473.1|AUY27846.1|670712_671921_+|Propionate-kinase
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
>CP026473.1|AUY27845.1|669355_670687_+|Threonine/serine-transporter-TdcC
MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
>CP026473.1|AUY27844.1|668344_669334_+|Threonine-dehydratase
MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA
>CP026473.1|AUY27843.1|667307_668246_+|HTH-type-transcriptional-regulator-TdcA
MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFGFPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKLQDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNGISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAVWSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG
>CP026473.1|AUY27842.1|665979_666519_-|hypothetical-protein
MKGFPIAHIFHPSIPPMHAVVNNHNRNIDYWTVKRKFAEIVSTNDVNKIYSISNELRRVLSAITALNFYQGDVPSVMIRIQPENMSPFIIDISTGEHDDYIIQTLDVGTFAPFGEQCTCSAVNKKELECIKETISKYCAKFTRKEAILTPPAHFNKTSITSDCWQILFFSPDHFNNDFY
>CP026473.1|AUY27841.1|664770_665958_-|hypothetical-protein
MFPVSSIGNDISSDLVRRKMNDLPESPIVNNLEALAPGIEKLKQTSIQMVTLLNALQPGGKCIITGDFQKELAYLQNVILYNDSSLRMDFFGYNALIIQRSDNTCELTINEPLKNQEISTGNINVNFPLKDIYNEIRRLNVVFSCGTGGIVDLSSLDLRNIDLELYDFTDKHMANAILNPFKLDDTDFTNANMFQVNFVSSKQNTTISWDYLLKITPVLTSISDMYSEEKIKLVESCLNELGDITEEQLKIMRFAIIESIPRATLTDQLENELTKEIYKNSSKINNYLNRIKLPEMKGFSSEKIDYYIDIIIKDYESVKENAYLIDPKINYNTDLNIEDSSSEEFLSDNTLEKDENSPDNCFEVVKYNTYEAYNSENLYFTREEYTYDYDLLNAI
>CP026473.1|AUY27851.1|677350_677515_-|hypothetical-protein
MSKKSAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAETRLAEDEATA
>CP026473.1|AUY27852.1|677537_678239_-|Pirin
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQQLIASPEGTMGSLQLRQQVWLHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV
>CP026473.1|AUY27853.1|678343_679240_+|LysR-family-transcriptional-regulator
MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIVTEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSSEINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLDKQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWRRDSMGEAKSWCLREIPKLFSGK
>CP026473.1|AUY27854.1|679290_679647_-|Inner-membrane-protein-YhaI
MQWYLAVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLILGLEFPFLSLIYLAATIIPVIALCVRRLHDTDRSGAWALLYLVPIIGWLVLFVFACLEGNSGSNRYGNDPKFGSN
>CP026473.1|AUY27855.1|679888_680254_-|Inner-membrane-protein-YhaH
MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKMLGWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFNCQAGTPGENRFGPDPKLEP
>CP026473.1|AUY27856.1|680546_681533_-|S-transferase
MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTGTGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQQAYDEAVAKVFESLARLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISNYLNLYGFLRDIYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG
>CP026473.1|AUY27857.1|681602_682085_-|Inner-membrane-protein-YqjF
MILSIDSNDANTAPLHKKTISSLSGAVESMMKKLEDVGVLVARILMPILFITAGWGKITGYAGTQQYMEAMGVPGFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKNLTISGGFLLLAITGPGAYSIDRLLNKKW
>CP026473.1|AUY27858.1|682180_682480_-|Inner-membrane-protein-YqjK
MSSKVERERRKAQLLSQIQQQRLDLSASRREWLEATGAYDRRWNMLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG
>CP026473.1|AUY27859.1|682469_682874_-|Inner-membrane-protein-YqjE
MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEKANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIWTLRKSRKSTLLRHTRHELANDRQLLEEESREQ
>CP026473.1|AUY27860.1|682876_683182_-|membrane-protein
MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAEQALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR

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Crispr_ID: CP026473_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026473_3

1050609-1051125

Unclear

I-E

Consensus_repeat	Method
GAGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

8 spacers

The CRISPR arrays of CP026473_3

>merge|CP026473|3|1050609-1051125|PILER-CR,CRISPRCasFinder,CRT
GAGTTCCCCGCGCCAGCGGGGATAAACCGTCCACGCTGTAACGGCCATCATTAAGTTTAGTGAGTTCCCCGCGCCAGCGGGGATAAACCGGCTGATGGTCTGGGAGTGTCCATCGGGCAACTGAGTTCCCCGCGCCAGCGGGGATAAACCGGAAGTAGGCCTGACAGTGATTGAACGCATACTGAGTTCCCCGCGCCAGCGGGGATAAACCGAGTTGGGGCGGCGCAATAACGAGACGATACGCGAGTTCCCCGCGCCAGCGGGGATAAACCGGGGAGTGGCACTTCTGGGGTAGCGGCGGCCCTGAGTTCCCCGCGCCAGCGGGGATAAACCGTCAACGCGCTCAGACGTTGCGTGAGTGAACCAGAGTTCCCCGCGCCAGCGGGGATAAACCGAAATATCCAGGGCTGGGCTGGAGGCAGACGGCGAGTTCCCCGCGCCAGCGGGGATAAACCGCCCGGAATGCATTCTGAAGGTTTGCTGTATATGAGTTCCCCGCGCCAGCGGGGATAAACCA

>CP026473|3|1|1050609-1051125|PILER-CR
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCCACGCTGTAACGGCCATCATTAAGTTTAGT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GCTGATGGTCTGGGAGTGTCCATCGGGCAACT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GAAGTAGGCCTGACAGTGATTGAACGCATACT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AGTTGGGGCGGCGCAATAACGAGACGATACGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGGAGTGGCACTTCTGGGGTAGCGGCGGCCCT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCAACGCGCTCAGACGTTGCGTGAGTGAACCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AAATATCCAGGGCTGGGCTGGAGGCAGACGGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGGAATGCATTCTGAAGGTTTGCTGTATAT
GAGTTCCCCGCGCCAGCGGGGATAAACCA

>CP026473|3|3|1050609-1051125|CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCCACGCTGTAACGGCCATCATTAAGTTTAGT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GCTGATGGTCTGGGAGTGTCCATCGGGCAACT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GAAGTAGGCCTGACAGTGATTGAACGCATACT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AGTTGGGGCGGCGCAATAACGAGACGATACGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGGAGTGGCACTTCTGGGGTAGCGGCGGCCCT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCAACGCGCTCAGACGTTGCGTGAGTGAACCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AAATATCCAGGGCTGGGCTGGAGGCAGACGGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGGAATGCATTCTGAAGGTTTGCTGTATAT
GAGTTCCCCGCGCCAGCGGGGATAAACCA

>CP026473|3|1|1050609-1051125|CRT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCCACGCTGTAACGGCCATCATTAAGTTTAGT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GCTGATGGTCTGGGAGTGTCCATCGGGCAACT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GAAGTAGGCCTGACAGTGATTGAACGCATACT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AGTTGGGGCGGCGCAATAACGAGACGATACGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGGAGTGGCACTTCTGGGGTAGCGGCGGCCCT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCAACGCGCTCAGACGTTGCGTGAGTGAACCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AAATATCCAGGGCTGGGCTGGAGGCAGACGGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGGAATGCATTCTGAAGGTTTGCTGTATAT
GAGTTCCCCGCGCCAGCGGGGATAAACCA

Protein	Signature genes	Signature genes Name	Protein_function
CP026473.1\|AUY28185.1\|1055718_1057173_+\|FAD-linked-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
CP026473.1\|AUY28178.1\|1047074_1048373_+\|Enolase	unknown	unknown	gnl\|CDD\|234617
CP026473.1\|AUY28179.1\|1048432_1049305_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224429
CP026473.1\|AUY28184.1\|1054863_1055649_+\|Oxidoreductase	unknown	unknown	gnl\|CDD\|187605
CP026473.1\|AUY28175.1\|1043924_1044260_+\|mRNA-interferase-MazF	unknown	unknown	gnl\|CDD\|182138
CP026473.1\|AUY28182.1\|1051762_1053241_-\|Kinase	unknown	unknown	gnl\|CDD\|212662
CP026473.1\|AUY28177.1\|1045349_1046987_+\|CTP-synthase	unknown	unknown	gnl\|CDD\|235437
CP026473.1\|AUY28180.1\|1049597_1050269_+\|7-carboxy-7-deazaguanine-synthase	unknown	unknown	gnl\|CDD\|275126
CP026473.1\|AUY28189.1\|1060365_1060941_-\|Glycerol-3-phosphate-responsive-antiterminator-family-protein	unknown	unknown	gnl\|CDD\|224865
CP026473.1\|AUY28186.1\|1057194_1058604_+\|Major-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|340929
CP026473.1\|AUY28188.1\|1059357_1060218_+\|Flavoprotein	unknown	unknown	gnl\|CDD\|224936
CP026473.1\|AUY28172.1\|1040015_1041317_+\|23S-rRNA-(uracil1939-C5)-methyltransferase	unknown	unknown	gnl\|CDD\|237291
CP026473.1\|AUY28190.1\|1060957_1061218_-\|Ferredoxin	unknown	unknown	gnl\|CDD\|225289
CP026473.1\|AUY28183.1\|1053267_1054545_-\|Transporter	unknown	unknown	gnl\|CDD\|349949
CP026473.1\|AUY28187.1\|1058581_1059361_+\|Electron-transfer-flavoprotein	unknown	unknown	gnl\|CDD\|224997
CP026473.1\|AUY28174.1\|1043676_1043925_+\|Antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
CP026473.1\|AUY28191.1\|1061208_1062480_-\|FAD-binding-domain-protein	unknown	unknown	gnl\|CDD\|182194
CP026473.1\|AUY28176.1\|1044330_1045122_+\|nucleoside-triphosphate-diphosphatase	unknown	unknown	gnl\|CDD\|236569
CP026473.1\|AUY28171.1\|1037202_1039959_-\|Signal-transduction-histidine-protein-kinase-BarA	unknown	unknown	gnl\|CDD\|236848
CP026473.1\|AUY28173.1\|1041364_1043599_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797

Protein	Function_ID	Function_description	E-value
CP026473.1\|AUY28185.1\|1055718_1057173_+\|FAD-linked-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.25325e-82
CP026473.1\|AUY28178.1\|1047074_1048373_+\|Enolase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
CP026473.1\|AUY28179.1\|1048432_1049305_-\|hypothetical-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	4.46208e-100
CP026473.1\|AUY28184.1\|1054863_1055649_+\|Oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.14687e-138
CP026473.1\|AUY28175.1\|1043924_1044260_+\|mRNA-interferase-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.17475e-74
CP026473.1\|AUY28182.1\|1051762_1053241_-\|Kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	9.76816e-108
CP026473.1\|AUY28177.1\|1045349_1046987_+\|CTP-synthase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
CP026473.1\|AUY28180.1\|1049597_1050269_+\|7-carboxy-7-deazaguanine-synthase	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.23739e-155
CP026473.1\|AUY28189.1\|1060365_1060941_-\|Glycerol-3-phosphate-responsive-antiterminator-family-protein	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
CP026473.1\|AUY28186.1\|1057194_1058604_+\|Major-facilitator-family-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.50431e-51
CP026473.1\|AUY28188.1\|1059357_1060218_+\|Flavoprotein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	1.47186e-88
CP026473.1\|AUY28172.1\|1040015_1041317_+\|23S-rRNA-(uracil1939-C5)-methyltransferase	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
CP026473.1\|AUY28190.1\|1060957_1061218_-\|Ferredoxin	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	3.6328e-41
CP026473.1\|AUY28183.1\|1053267_1054545_-\|Transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	5.26475e-29
CP026473.1\|AUY28187.1\|1058581_1059361_+\|Electron-transfer-flavoprotein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	7.46503e-62
CP026473.1\|AUY28174.1\|1043676_1043925_+\|Antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
CP026473.1\|AUY28191.1\|1061208_1062480_-\|FAD-binding-domain-protein	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	2.82789e-125
CP026473.1\|AUY28176.1\|1044330_1045122_+\|nucleoside-triphosphate-diphosphatase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
CP026473.1\|AUY28171.1\|1037202_1039959_-\|Signal-transduction-histidine-protein-kinase-BarA	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	0
CP026473.1\|AUY28173.1\|1041364_1043599_+\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0

>CP026473.1|AUY28180.1|1049597_1050269_+|7-carboxy-7-deazaguanine-synthase
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVISRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>CP026473.1|AUY28179.1|1048432_1049305_-|hypothetical-protein
MRYFILMFTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKELTHKLESIFNNTQVQIAVLIVPTTKDETIEQYATRVFDNWRLGDAKRNDGILIIVAWSDRTVRIKVGYGLEEKVTDALAGDIIRSNMIPAFKQQKLAQGLELAINALNNQLTSQHQYPTNPSESESASSSDHYYFAIFWVFAVMFFPFWFFHQCSNFCRACKSGVCISAIYLLDLFLFSDKIFSIAVFSFFFTFTIFMVFTCLCVLQKRASGRSYHSDNSGSAGGSDSGGFSGGGGSSGGGGASGRW
>CP026473.1|AUY28178.1|1047074_1048373_+|Enolase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>CP026473.1|AUY28177.1|1045349_1046987_+|CTP-synthase
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>CP026473.1|AUY28176.1|1044330_1045122_+|nucleoside-triphosphate-diphosphatase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>CP026473.1|AUY28175.1|1043924_1044260_+|mRNA-interferase-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>CP026473.1|AUY28174.1|1043676_1043925_+|Antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>CP026473.1|AUY28173.1|1041364_1043599_+|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>CP026473.1|AUY28172.1|1040015_1041317_+|23S-rRNA-(uracil1939-C5)-methyltransferase
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHDVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILAPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>CP026473.1|AUY28171.1|1037202_1039959_-|Signal-transduction-histidine-protein-kinase-BarA
MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFHLDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYIALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYSPTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPEVNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRNGTKEEDLEPELLELLDEMDNVAREASKILG
>CP026473.1|AUY28182.1|1051762_1053241_-|Kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDAKAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNYFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFMPVESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNADSIQSWSNA
>CP026473.1|AUY28183.1|1053267_1054545_-|Transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSTSLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSIIGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALGMVIVFIFLLFQKIRTADSAPAMASSK
>CP026473.1|AUY28184.1|1054863_1055649_+|Oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAASCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>CP026473.1|AUY28185.1|1055718_1057173_+|FAD-linked-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>CP026473.1|AUY28186.1|1057194_1058604_+|Major-facilitator-family-transporter
MTGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>CP026473.1|AUY28187.1|1058581_1059361_+|Electron-transfer-flavoprotein
MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRTEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWRDYLRQRMQP
>CP026473.1|AUY28188.1|1059357_1060218_+|Flavoprotein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGAAKNATLPSGMQQLIIVPGALPDWLVSTEDLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ
>CP026473.1|AUY28189.1|1060365_1060941_-|Glycerol-3-phosphate-responsive-antiterminator-family-protein
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>CP026473.1|AUY28190.1|1060957_1061218_-|Ferredoxin
MSVARNLWRVADAPHIVPADSVERQTAERLISACPAGLFSLTPEGDLRIDYRSCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>CP026473.1|AUY28191.1|1061208_1062480_-|FAD-binding-domain-protein
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERCITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLFWHHLRRHGLWHLAGDVIRSLRCL

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Crispr_ID: CP026473_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026473_4

1073510-1074088

Unclear

I-E

Consensus_repeat	Method
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

9 spacers

cas2,cas1,cas6e,cas5,cas7,cas3

The CRISPR arrays of CP026473_4

>merge|CP026473|4|1073510-1074088|CRISPRCasFinder,PILER-CR,CRT
TGTGTTCCCCGCGCCAGCGGGGATAAACCGTTGCCCGCGCAATTCCGGGAGCATCCGCAATTGTGTTCCCCGCGCCAGCGGGGATAAACCGACGGACAAAATATATATTGATTTGCGAATTATGTGTTCCCCGCGCCAGCGGGGATAAACCGGTAAAGAAACTGCCGACAAATCCCTGTTCGTTGTGTTCCCCGCGCCAGCGGGGATAAACCGCCCGTCACCGACGCGCAGTGGCGCTACCGTGAGTGTTCCCCGCGCCAGCGGGGATAAACCGGGATCTAACGCGCTGTAAAAATTCCGTGCTTTGTGTTCCCCGCGCCAGCGGGGATAAACCATGCGGATTACCGGCAAAACATGGGAGCAAACCGTGTTCCCCGCGCCAGCGGGGATAAACCGCCGAACGGCTGGCGAAGCAGGTGGCTGGCGTAGTGTTCCCCGCGCCAGCGGGGATAAACCGGTTTACCGCCCCGCAGAGGCGCTGGCAGATCCGTGTTCCCCGCGCCAGCGGGGATAAACCGGGATGACCTGTCGCTAAAACTCGCCGCGTACAGTGTTCCCCGCGCCAGCGGGGATAAACCG

>CP026473|4|4|1073510-1074088|CRISPRCasFinder
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGCCCGCGCAATTCCGGGAGCATCCGCAAT
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGACAAAATATATATTGATTTGCGAATTA
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	GTAAAGAAACTGCCGACAAATCCCTGTTCGT
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGTCACCGACGCGCAGTGGCGCTACCGTG
AGTGTTCCCCGCGCCAGCGGGGATAAACCG	GGATCTAACGCGCTGTAAAAATTCCGTGCTT
TGTGTTCCCCGCGCCAGCGGGGATAAACCA	TGCGGATTACCGGCAAAACATGGGAGCAAAC
CGTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGAACGGCTGGCGAAGCAGGTGGCTGGCGT
AGTGTTCCCCGCGCCAGCGGGGATAAACCG	GTTTACCGCCCCGCAGAGGCGCTGGCAGATC
CGTGTTCCCCGCGCCAGCGGGGATAAACCG	GGATGACCTGTCGCTAAAACTCGCCGCGTAC
AGTGTTCCCCGCGCCAGCGGGGATAAACCG

>CP026473|4|2|1073511-1074088|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGCCCGCGCAATTCCGGGAGCATCCGCAATT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGACAAAATATATATTGATTTGCGAATTAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTAAAGAAACTGCCGACAAATCCCTGTTCGTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGTCACCGACGCGCAGTGGCGCTACCGTGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGATCTAACGCGCTGTAAAAATTCCGTGCTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCA	TGCGGATTACCGGCAAAACATGGGAGCAAACC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGAACGGCTGGCGAAGCAGGTGGCTGGCGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTTTACCGCCCCGCAGAGGCGCTGGCAGATCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGATGACCTGTCGCTAAAACTCGCCGCGTACA
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>CP026473|4|2|1073511-1074088|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGCCCGCGCAATTCCGGGAGCATCCGCAATT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGACAAAATATATATTGATTTGCGAATTAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTAAAGAAACTGCCGACAAATCCCTGTTCGTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGTCACCGACGCGCAGTGGCGCTACCGTGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGATCTAACGCGCTGTAAAAATTCCGTGCTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCA	TGCGGATTACCGGCAAAACATGGGAGCAAACC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGAACGGCTGGCGAAGCAGGTGGCTGGCGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTTTACCGCCCCGCAGAGGCGCTGGCAGATCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGATGACCTGTCGCTAAAACTCGCCGCGTACA
GTGTTCCCCGCGCCAGCGGGGATAAACCG

Protein	Signature genes	Signature genes Name	Protein_function
CP026473.1\|AUY28195.1\|1068168_1069956_+\|CRISPR-associated-endonuclease-Cas3-HD	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
CP026473.1\|AUY28199.1\|1072200_1073124_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
CP026473.1\|AUY28198.1\|1071553_1072204_+\|CRISPR-associated-protein-Cas6	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
CP026473.1\|AUY28206.1\|1078967_1079279_+\|Cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
CP026473.1\|AUY28193.1\|1065037_1066750_+\|Sulfite-reductase-[NADPH]-hemoprotein-beta-component	unknown	unknown	gnl\|CDD\|237402
CP026473.1\|AUY28203.1\|1076368_1077796_+\|Sulfate-adenylyltransferase-subunit-1	unknown	unknown	gnl\|CDD\|235349
CP026473.1\|AUY28209.1\|1080483_1081533_+\|tRNA-pseudouridine-synthase-D	unknown	unknown	gnl\|CDD\|234884
CP026473.1\|AUY28207.1\|1079297_1080008_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
CP026473.1\|AUY28200.1\|1073120_1073414_+\|SsRNA-endonuclease	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
CP026473.1\|AUY28204.1\|1077795_1078401_+\|Adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
CP026473.1\|AUY28192.1\|1063238_1065038_+\|Sulfite-reductase-[NADPH]-flavoprotein-alpha-component	unknown	unknown	gnl\|CDD\|182862
CP026473.1\|AUY28208.1\|1080007_1080487_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
CP026473.1\|AUY28202.1\|1075458_1076367_+\|Sulfate-adenylyltransferase-subunit-2	unknown	unknown	gnl\|CDD\|235375
CP026473.1\|AUY28196.1\|1069900_1070815_+\|CRISPR-associated-protein-cas7/cse4/casc,-subtype-I-e	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|187777
CP026473.1\|AUY28194.1\|1066823_1067558_+\|Phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
CP026473.1\|AUY28201.1\|1074169_1075207_-\|Alkaline-phosphatase	unknown	unknown	gnl\|CDD\|182299
CP026473.1\|AUY28205.1\|1078450_1078774_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371891
CP026473.1\|AUY28191.1\|1061208_1062480_-\|FAD-binding-domain-protein	unknown	unknown	gnl\|CDD\|182194
CP026473.1\|AUY28210.1\|1081513_1082275_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
CP026473.1\|AUY28197.1\|1070825_1071572_+\|Crispr-associated-protein-cas5	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776

Protein	Function_ID	Function_description	E-value
CP026473.1\|AUY28195.1\|1068168_1069956_+\|CRISPR-associated-endonuclease-Cas3-HD	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.2897e-101
CP026473.1\|AUY28199.1\|1072200_1073124_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	6.67486e-158
CP026473.1\|AUY28198.1\|1071553_1072204_+\|CRISPR-associated-protein-Cas6	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	1.0289e-91
CP026473.1\|AUY28206.1\|1078967_1079279_+\|Cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
CP026473.1\|AUY28193.1\|1065037_1066750_+\|Sulfite-reductase-[NADPH]-hemoprotein-beta-component	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
CP026473.1\|AUY28203.1\|1076368_1077796_+\|Sulfate-adenylyltransferase-subunit-1	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
CP026473.1\|AUY28209.1\|1080483_1081533_+\|tRNA-pseudouridine-synthase-D	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
CP026473.1\|AUY28207.1\|1079297_1080008_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
CP026473.1\|AUY28200.1\|1073120_1073414_+\|SsRNA-endonuclease	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
CP026473.1\|AUY28204.1\|1077795_1078401_+\|Adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
CP026473.1\|AUY28192.1\|1063238_1065038_+\|Sulfite-reductase-[NADPH]-flavoprotein-alpha-component	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
CP026473.1\|AUY28208.1\|1080007_1080487_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	3.39469e-104
CP026473.1\|AUY28202.1\|1075458_1076367_+\|Sulfate-adenylyltransferase-subunit-2	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
CP026473.1\|AUY28196.1\|1069900_1070815_+\|CRISPR-associated-protein-cas7/cse4/casc,-subtype-I-e	gnl\|CDD\|187777	cd09646, Cas7_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cse4/CasC family.	8.81908e-119
CP026473.1\|AUY28194.1\|1066823_1067558_+\|Phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.33579e-136
CP026473.1\|AUY28201.1\|1074169_1075207_-\|Alkaline-phosphatase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
CP026473.1\|AUY28205.1\|1078450_1078774_+\|hypothetical-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
CP026473.1\|AUY28191.1\|1061208_1062480_-\|FAD-binding-domain-protein	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	2.82789e-125
CP026473.1\|AUY28210.1\|1081513_1082275_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	5.52694e-150
CP026473.1\|AUY28197.1\|1070825_1071572_+\|Crispr-associated-protein-cas5	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	5.83917e-49

>CP026473.1|AUY28200.1|1073120_1073414_+|SsRNA-endonuclease
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>CP026473.1|AUY28199.1|1072200_1073124_+|CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRGG
>CP026473.1|AUY28198.1|1071553_1072204_+|CRISPR-associated-protein-Cas6
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESDTFTIECRSFAPELRTGQQLCFNLRANPTICKSGKRHDLLMEAKRQVRGQAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEA
>CP026473.1|AUY28197.1|1070825_1071572_+|Crispr-associated-protein-cas5
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTIQMPKEVRKARYFSRREELSDPDLLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNACDALCNAYQQYQDHFHKLKVSLPKLQDECWWEGEHDGLVASKILRRRDVPLNRQQWLFGERTINQGPWLSKEEPCTSQE
>CP026473.1|AUY28196.1|1069900_1070815_+|CRISPR-associated-protein-cas7/cse4/casc,-subtype-I-e
MTLLRFIVSYLAGHIGIRSGRIAREAATILIEKGIEEKKAIEWAAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKSEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWAMAEKGTEQPRSLAAAFYEPINGTRQLEVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>CP026473.1|AUY28195.1|1068168_1069956_+|CRISPR-associated-endonuclease-Cas3-HD
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKEGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGRPPDRMDELDNFLPEDKAAARDFLLAIKALFPRIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAQAMDIKHYWQKALVQAQNALTVFPPKAETAPFTGINTLFPFIENPTPLQQKVLDLDISQPGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGAEGQQEAPLLGKDDYPWLTHVTKTDVHSHRVATRKEVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIKVYRQLLGGPYWYS
>CP026473.1|AUY28194.1|1066823_1067558_+|Phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMLEEETRFFGLKRECGLHEG
>CP026473.1|AUY28193.1|1065037_1066750_+|Sulfite-reductase-[NADPH]-hemoprotein-beta-component
MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD
>CP026473.1|AUY28192.1|1063238_1065038_+|Sulfite-reductase-[NADPH]-flavoprotein-alpha-component
MTTQVPPSALLPLNPEQLVRLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKDGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
>CP026473.1|AUY28191.1|1061208_1062480_-|FAD-binding-domain-protein
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERCITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLFWHHLRRHGLWHLAGDVIRSLRCL
>CP026473.1|AUY28201.1|1074169_1075207_-|Alkaline-phosphatase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>CP026473.1|AUY28202.1|1075458_1076367_+|Sulfate-adenylyltransferase-subunit-2
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>CP026473.1|AUY28203.1|1076368_1077796_+|Sulfate-adenylyltransferase-subunit-1
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEKTFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMAWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>CP026473.1|AUY28204.1|1077795_1078401_+|Adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>CP026473.1|AUY28205.1|1078450_1078774_+|hypothetical-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>CP026473.1|AUY28206.1|1078967_1079279_+|Cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>CP026473.1|AUY28207.1|1079297_1080008_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>CP026473.1|AUY28208.1|1080007_1080487_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYERGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>CP026473.1|AUY28209.1|1080483_1081533_+|tRNA-pseudouridine-synthase-D
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>CP026473.1|AUY28210.1|1081513_1082275_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVICSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Crispr_ID: CP026473_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026473_5

1579258-1579375

Orphan

Consensus_repeat	Method
CCGAGCCGTAGGCCGGATAAGGCGTTCACGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026473_5

>merge|CP026473|5|1579258-1579375|CRISPRCasFinder
CCGAGCCGTAGGCCGGATAAGGCGTTCACGCTGCATCCGGCACCCGGAGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAACCGAGCCGTAGGCCGGATAAGGCGTTTACGC

>CP026473|5|5|1579258-1579375|CRISPRCasFinder
CCGAGCCGTAGGCCGGATAAGGCGTTCACGC	TGCATCCGGCACCCGGAGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAA
CCGAGCCGTAGGCCGGATAAGGCGTTTACGC

Protein	Signature genes	Signature genes Name	Protein_function
CP026473.1\|AUY28630.1\|1578030_1579161_-\|ribonucleoside-diphosphate-reductase-beta-chain	unknown	unknown	gnl\|CDD\|181647
CP026473.1\|AUY28632.1\|1582375_1586128_+\|Outer-membrane-autotransporter-barrel-domain-protein	unknown	unknown	gnl\|CDD\|182059
CP026473.1\|AUY28623.1\|1568530_1569790_-\|glycerol-3-phosphate-dehydrogenase-subunit-B	unknown	unknown	gnl\|CDD\|225617
CP026473.1\|AUY28625.1\|1571680_1573039_+\|Glycerol-3-phosphate-transporter	unknown	unknown	gnl\|CDD\|236889
CP026473.1\|AUY28636.1\|1591585_1592209_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225774
CP026473.1\|AUY28631.1\|1579394_1581680_-\|ribonucleoside-diphosphate-reductase-alpha-chain	unknown	unknown	gnl\|CDD\|181649
CP026473.1\|AUY28621.1\|1566251_1567151_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182167
CP026473.1\|AUY28639.1\|1598401_1599178_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227021
CP026473.1\|AUY28633.1\|1586255_1586978_-\|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase	unknown	unknown	gnl\|CDD\|235350
CP026473.1\|AUY28628.1\|1577072_1577723_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182136
CP026473.1\|AUY28640.1\|1599251_1600436_-\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|180261
CP026473.1\|AUY28634.1\|1587124_1589752_+\|DNA-gyrase-subunit-A	unknown	unknown	gnl\|CDD\|235502
CP026473.1\|AUY28624.1\|1569779_1571408_-\|glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|236847
CP026473.1\|AUY28622.1\|1567343_1568534_-\|glycerol-3-phosphate-dehydrogenase-subunit-C	unknown	unknown	gnl\|CDD\|132422
CP026473.1\|AUY28637.1\|1592352_1596747_+\|Alpha-2-macroglobulin-family-protein	unknown	unknown	gnl\|CDD\|225248
CP026473.1\|AUY28626.1\|1573043_1574120_+\|Glycerophosphoryl-diester-phosphodiesterase-GlpQ	unknown	unknown	gnl\|CDD\|236859
CP026473.1\|AUY28635.1\|1589900_1591589_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227030
CP026473.1\|AUY28627.1\|1576651_1576858_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182050
CP026473.1\|AUY28629.1\|1577776_1578031_-\|2Fe-2S-iron-sulfur-cluster-binding-domain	unknown	unknown	gnl\|CDD\|182668
CP026473.1\|AUY28638.1\|1596747_1598397_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227732

Protein	Function_ID	Function_description	E-value
CP026473.1\|AUY28630.1\|1578030_1579161_-\|ribonucleoside-diphosphate-reductase-beta-chain	gnl\|CDD\|181647	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed.	0
CP026473.1\|AUY28632.1\|1582375_1586128_+\|Outer-membrane-autotransporter-barrel-domain-protein	gnl\|CDD\|182059	PRK09752, PRK09752, AIDA-I family autotransporter YfaL.	0
CP026473.1\|AUY28623.1\|1568530_1569790_-\|glycerol-3-phosphate-dehydrogenase-subunit-B	gnl\|CDD\|225617	COG3075, GlpB, Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism].	0
CP026473.1\|AUY28625.1\|1571680_1573039_+\|Glycerol-3-phosphate-transporter	gnl\|CDD\|236889	PRK11273, glpT, glycerol-3-phosphate transporter.	0
CP026473.1\|AUY28636.1\|1591585_1592209_+\|hypothetical-protein	gnl\|CDD\|225774	COG3234, COG3234, Uncharacterized protein conserved in bacteria [Function unknown].	7.99004e-141
CP026473.1\|AUY28631.1\|1579394_1581680_-\|ribonucleoside-diphosphate-reductase-alpha-chain	gnl\|CDD\|181649	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha.	0
CP026473.1\|AUY28621.1\|1566251_1567151_-\|hypothetical-protein	gnl\|CDD\|182167	PRK09956, PRK09956, ISNCY family transposase.	0
CP026473.1\|AUY28639.1\|1598401_1599178_+\|hypothetical-protein	gnl\|CDD\|227021	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown].	1.0163e-152
CP026473.1\|AUY28633.1\|1586255_1586978_-\|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase	gnl\|CDD\|235350	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG.	9.80223e-171
CP026473.1\|AUY28628.1\|1577072_1577723_+\|hypothetical-protein	gnl\|CDD\|182136	PRK09902, PRK09902, lipopolysaccharide kinase InaA.	1.43283e-158
CP026473.1\|AUY28640.1\|1599251_1600436_-\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
CP026473.1\|AUY28634.1\|1587124_1589752_+\|DNA-gyrase-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
CP026473.1\|AUY28624.1\|1569779_1571408_-\|glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|236847	PRK11101, glpA, anaerobic glycerol-3-phosphate dehydrogenase subunit A.	0
CP026473.1\|AUY28622.1\|1567343_1568534_-\|glycerol-3-phosphate-dehydrogenase-subunit-C	gnl\|CDD\|132422	TIGR03379, glycerol3P_GlpC, glycerol-3-phosphate dehydrogenase, anaerobic, C subunit. Members of this protein family are the membrane-anchoring, non-catalytic C subunit, product of the glpC gene, of a three-subunit, FAD-dependent, anaerobic glycerol-3-phosphate dehydrogenase. GlpC lasks classical hydrophobic transmembrane helices; Cole, et al suggest interaction with the membrane may involve amphipathic helices. GlcC has conserved Cys-containing motifs suggestive of iron-sulfur binding. This complex is found mostly in Escherichia coli and closely related species. [Energy metabolism, Anaerobic].	0
CP026473.1\|AUY28637.1\|1592352_1596747_+\|Alpha-2-macroglobulin-family-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
CP026473.1\|AUY28626.1\|1573043_1574120_+\|Glycerophosphoryl-diester-phosphodiesterase-GlpQ	gnl\|CDD\|236859	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional.	0
CP026473.1\|AUY28635.1\|1589900_1591589_+\|hypothetical-protein	gnl\|CDD\|227030	COG4685, COG4685, Uncharacterized protein conserved in bacteria [Function unknown].	0
CP026473.1\|AUY28627.1\|1576651_1576858_-\|hypothetical-protein	gnl\|CDD\|182050	PRK09729, PRK09729, hypothetical protein; Provisional.	2.02381e-36
CP026473.1\|AUY28629.1\|1577776_1578031_-\|2Fe-2S-iron-sulfur-cluster-binding-domain	gnl\|CDD\|182668	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein.	2.72138e-53
CP026473.1\|AUY28638.1\|1596747_1598397_+\|hypothetical-protein	gnl\|CDD\|227732	COG5445, COG5445, Predicted secreted protein [Function unknown].	2.06112e-125

>CP026473.1|AUY28630.1|1578030_1579161_-|ribonucleoside-diphosphate-reductase-beta-chain
MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVSDNVQVAPQEVEVSSYLVGQIDSEVDTDDLSNFQL
>CP026473.1|AUY28629.1|1577776_1578031_-|2Fe-2S-iron-sulfur-cluster-binding-domain
MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM
>CP026473.1|AUY28628.1|1577072_1577723_+|hypothetical-protein
MAVSAKYDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAQHAVSPYSDEVRQAMLKAVALAFKKMHSINRQHGCCYVRHIYVKTEGKAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM
>CP026473.1|AUY28627.1|1576651_1576858_-|hypothetical-protein
MNFIRQGLGIALQPELTLKSIAGELCSVPLEPTFYRQISLLAKEKPVEGSPLFLLQTCTEQLVVSGKI
>CP026473.1|AUY28626.1|1573043_1574120_+|Glycerophosphoryl-diester-phosphodiesterase-GlpQ
MKLKLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLPEHTLPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRYYAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNHSTGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRIKNELEPKMGMDLNLVQLIAYTDWNETQQKQPDGSWVNYSYDWMFKPGAMKQVAEYADGIGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTTDVNQLYDVLYNKAGVNGLFTDFPDKAVKFLNKE
>CP026473.1|AUY28625.1|1571680_1573039_+|Glycerol-3-phosphate-transporter
MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSVWNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQKRNGG
>CP026473.1|AUY28624.1|1569779_1571408_-|glycerol-3-phosphate-dehydrogenase
MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQDPAEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL
>CP026473.1|AUY28623.1|1568530_1569790_-|glycerol-3-phosphate-dehydrogenase-subunit-B
MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVADIHSGLESLRQQAPAHPYSLLGPQRVLDLACQAQALIAESGAQLQGSVELAHQRITPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELDLSVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVMNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
>CP026473.1|AUY28622.1|1567343_1568534_-|glycerol-3-phosphate-dehydrogenase-subunit-C
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYKDQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTAKARKQAITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGLELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA
>CP026473.1|AUY28621.1|1566251_1567151_-|hypothetical-protein
MTESTTSSPHDAVFKTFMFTPETARDFLEIHLPEPLRKLCNLQTLRLEPTSFIEKSLRAYYSDVLWSVETSDGDGYIYCVIEHQSSAEKNMAFRLMRYATAAMQRHLDKGYDRVPLVVPLLFYHGETSPYPYSLNWLDEFDDPQLARQLYTEAFPLVDITIVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVKGFTNDSQLQTLFNYLLQCGDTSRFTRFIEEIAKRSPLQKERLMTIAERLRQEGHQIGWQEGMHEQAIKIALRMLEQGFEREIVLATTQLTDADIPNCH
>CP026473.1|AUY28631.1|1579394_1581680_-|ribonucleoside-diphosphate-reductase-alpha-chain
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
>CP026473.1|AUY28632.1|1582375_1586128_+|Outer-membrane-autotransporter-barrel-domain-protein
MRIIFLRKEYLSLLPSMIASLFSANGVAAVTDSCQGYDVKASCQASRQSLSGITQDWSIADGQWLVFSDMTNNASGGAVFLQQGAEFSLLPENETGMTLFANNTVTGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNAMFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIVNNTAFTNNTAEGYGGAIYTNSVTAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDQYQNQAELNVGSTQQTFVHALTGFQNGTLNIDAGGNVTVNQGSFAGIIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDDGAVLSLEGDAADLTALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQVSLANNNSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITSDVDTRSDAAGHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADILPYASSLWVGDGATFVTGADQDIQSIDAISSGTIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNTSGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKMVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPDPDPTPDPDPTPDPDPTPDPEPTPAYQPVLNAKVGGYLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGTDGEWMLGIVGGYSDNQGDSRSNMTGTRADNQNHGYAVGLTSSWFQHGNQKQGAWLDSWLQYAWFSNDVSEQEDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDGSTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW
>CP026473.1|AUY28633.1|1586255_1586978_-|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase
MNAEKSPENHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEKHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNSFKLGPGVDVNYMLHTQNK
>CP026473.1|AUY28634.1|1587124_1589752_+|DNA-gyrase-subunit-A
MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDLAVYNTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE
>CP026473.1|AUY28635.1|1589900_1591589_+|hypothetical-protein
MSGEKKAKGWRFYGLVGFGAIALLSAGVWALQYAGSGPEKTLSPLVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIEGSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPLLFAATSDSQLSKTEISSIKINSETVPVYQLRYNGNNALMFATYQDKMLVFSSTDMLFKDDQQDTEATAIAGDLLSGKKRWQASFGLEERTAEKTPVRQRIVVSARWLGFGYQRLMPSFAGVRFEMGNDGWHSFVALNDESASVDASFDFTPVWNSMPAGASFCVAVPYSHGIAEEMLSHISQENDKLNGALDGAAGLCWYEDSKLQTPLFVGQFDGTAEQAQLPGKLFTQNIGAHESKAPEGVLPVSQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLAMQNKTLLFSLDDTLVNNALQTLNKTRPAMVDVIPTDGIVPLYINPQGIAKLLRNETLTSLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL
>CP026473.1|AUY28636.1|1591585_1592209_+|hypothetical-protein
MRHGLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQGPSPRWYQQDCAGLVRFAANETLKVHDSKWLKSNGLSSQYLPPEMTLTPEQRQLAQNWNQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYHTGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR
>CP026473.1|AUY28637.1|1592352_1596747_+|Alpha-2-macroglobulin-family-protein
MRLEAPGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKNLHRIVVQPQYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQALPELQLGNAIIKPSRYVQNNQFSPLKKYPLVEQFRYPLWQAKPFEPQQGVKLEGASSNFISPQPGNIYIPLGQQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGNELLVWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTDRPLYRAGDRVDVKVMGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTVDVTLDARNGGQGSFRLPENAVAGGYELRLAYRNQVYSSSFRVANYIKPHFEIGLALAKKEFKTGEAVSGKLQLLYPDGEPVKNARVQLSLRAQQLSMVGNDLRYAGRFPVSLEGSETVSDASGHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESSKQVPVTYEWLRLEDRTSHSGELPSGGKSFTVNFAKPGNYNLTLRDKDGLILAGLSHAVSGKGSTAHTGTVDIVADKTLYQPGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQNAGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTSSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSEKNLYMKWSMPTVYRVGDKPAAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQNIQQSGLLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGDNALMLPEQASNIRLQSSETPQEIFRNNLDALVDEPWGGVINTGSRLIPLSLAWRSLADHQSAAANDIRQMIQVNRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQAIGVTQQPEYWQHMLDSYAEQADNMPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTEDFSEEDTRDINDSLILDTPESPLADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQAAAILSGLTAEQSTIERALAMNWLAKYMATMPPVVLPAPAGAWAKHKLTGGGEYWRWVGQGVPDILSFGDELSPQNVQVRWREPAKTAQQSNIPVTVERQLYRLITGEEEMSFTLQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAAKQQGQLLEIARNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYMRSYAPAQQSVAAGSEWTRMQVK
>CP026473.1|AUY28638.1|1596747_1598397_+|hypothetical-protein
MNWRRIVWLLALVTLPTLAEEPPLQLALRGAQHDQLYKLSSSGVTNVSTLPDTLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRDTALVRSCGLYFAPQRLHIGADVWGQYWQQRQAPAWLASLTTLKPETSVTVKSLLDSLATLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTDGTPLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKITAEKSTTAVKPGVLNGRYRVTFTNGNHITFVSHGETTLLSEKGKLKLQSHLDREEYVARVLDREAKSTPPEAAKAMTVAIRTFLQQNANREGDCLTIPDSSATQRVSASPATTGARTMAAWTQDLIYAGDPVHYHGSRATEGTLSWRQATAQAGQGERYDQILAFAYPDNSLSRWGAPRSTCQLLPKAKAWLAKKMPQWRRILQAETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRNFFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD
>CP026473.1|AUY28639.1|1598401_1599178_+|hypothetical-protein
MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPVEGEDASFSQSINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRIESDGSFARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGTGTIRARLRLVLSWDTDNTDLDLHVVTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPVHGRYQVYINYYGGRSETELTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW
>CP026473.1|AUY28640.1|1599251_1600436_-|acetyl-CoA-C-acetyltransferase
MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKANSTAEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKTLGFDPEKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIERLN

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Crispr_ID: CP026473_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026473_6

2266208-2266331

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026473_6

>merge|CP026473|6|2266208-2266331|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>CP026473|6|6|2266208-2266331|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
CP026473.1\|AUY29235.1\|2273903_2274929_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739
CP026473.1\|AUY29238.1\|2277506_2278322_-\|Endopeptidase	unknown	unknown	gnl\|CDD\|366353
CP026473.1\|AUY29226.1\|2263261_2264026_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182159
CP026473.1\|AUY29236.1\|2275482_2276652_+\|Inner-membrane-transport-protein-ydhP	unknown	unknown	gnl\|CDD\|225371
CP026473.1\|AUY29228.1\|2265767_2266073_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182975
CP026473.1\|AUY29222.1\|2258942_2261045_+\|Aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629
CP026473.1\|AUY29231.1\|2269530_2270172_+\|Riboflavin-synthase-alpha-subunit	unknown	unknown	gnl\|CDD\|183846
CP026473.1\|AUY29221.1\|2258295_2258922_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182135
CP026473.1\|AUY29237.1\|2276797_2277379_-\|Superoxide-dismutase	unknown	unknown	gnl\|CDD\|182534
CP026473.1\|AUY29227.1\|2264037_2265642_-\|FAD/NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|182134
CP026473.1\|AUY29219.1\|2255115_2255352_-\|Major-outer-membrane-lipoprotein	unknown	unknown	gnl\|CDD\|185294
CP026473.1\|AUY29223.1\|2261057_2261696_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182160
CP026473.1\|AUY29234.1\|2272974_2273907_+\|HTH-type-transcriptional-regulator-YdhB	unknown	unknown	gnl\|CDD\|182948
CP026473.1\|AUY29229.1\|2266645_2267902_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|137602
CP026473.1\|AUY29224.1\|2261759_2262428_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274451
CP026473.1\|AUY29233.1\|2271650_2272862_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
CP026473.1\|AUY29232.1\|2270211_2271360_-\|Cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
CP026473.1\|AUY29230.1\|2267942_2269316_-\|Multidrug-resistance-efflux-pump-MdtK	unknown	unknown	gnl\|CDD\|234981
CP026473.1\|AUY29225.1\|2262424_2263210_+\|Thiosulfate-reductase-cytochrome-B-subunit	unknown	unknown	gnl\|CDD\|184968
CP026473.1\|AUY29220.1\|2257630_2257840_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182359

Protein	Function_ID	Function_description	E-value
CP026473.1\|AUY29235.1\|2273903_2274929_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
CP026473.1\|AUY29238.1\|2277506_2278322_-\|Endopeptidase	gnl\|CDD\|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	7.77757e-47
CP026473.1\|AUY29226.1\|2263261_2264026_+\|hypothetical-protein	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	9.5135e-164
CP026473.1\|AUY29236.1\|2275482_2276652_+\|Inner-membrane-transport-protein-ydhP	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.92383e-98
CP026473.1\|AUY29228.1\|2265767_2266073_-\|hypothetical-protein	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	1.12003e-64
CP026473.1\|AUY29222.1\|2258942_2261045_+\|Aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0
CP026473.1\|AUY29231.1\|2269530_2270172_+\|Riboflavin-synthase-alpha-subunit	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.8868e-122
CP026473.1\|AUY29221.1\|2258295_2258922_+\|hypothetical-protein	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	6.99609e-140
CP026473.1\|AUY29237.1\|2276797_2277379_-\|Superoxide-dismutase	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	3.77321e-138
CP026473.1\|AUY29227.1\|2264037_2265642_-\|FAD/NAD(P)-binding-domain-containing-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
CP026473.1\|AUY29219.1\|2255115_2255352_-\|Major-outer-membrane-lipoprotein	gnl\|CDD\|185294	PRK15396, PRK15396, major outer membrane lipoprotein.	2.83509e-37
CP026473.1\|AUY29223.1\|2261057_2261696_+\|hypothetical-protein	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	1.93584e-120
CP026473.1\|AUY29234.1\|2272974_2273907_+\|HTH-type-transcriptional-regulator-YdhB	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
CP026473.1\|AUY29229.1\|2266645_2267902_+\|hypothetical-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
CP026473.1\|AUY29224.1\|2261759_2262428_+\|hypothetical-protein	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	2.09652e-76
CP026473.1\|AUY29233.1\|2271650_2272862_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
CP026473.1\|AUY29232.1\|2270211_2271360_-\|Cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
CP026473.1\|AUY29230.1\|2267942_2269316_-\|Multidrug-resistance-efflux-pump-MdtK	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
CP026473.1\|AUY29225.1\|2262424_2263210_+\|Thiosulfate-reductase-cytochrome-B-subunit	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	5.33298e-163
CP026473.1\|AUY29220.1\|2257630_2257840_+\|hypothetical-protein	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34

>CP026473.1|AUY29228.1|2265767_2266073_-|hypothetical-protein
MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA
>CP026473.1|AUY29227.1|2264037_2265642_-|FAD/NAD(P)-binding-domain-containing-protein
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPINCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLVVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFNRDNASEKLNITLMSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYEMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>CP026473.1|AUY29226.1|2263261_2264026_+|hypothetical-protein
MYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGEIPFCSQFARSDDHARIGCCEDNARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRIANTGMRVRVCTLGERCHVASNGDLAQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRAGVRYRLNEQHQFVEC
>CP026473.1|AUY29225.1|2262424_2263210_+|Thiosulfate-reductase-cytochrome-B-subunit
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSVTDYGEKIYLYCKAVRLWHWSNALLFVLLLASGLINHFALVGATAVKSLVAVHEVCGFLLLACWLGFVLINAVGGNGHHYRIRRQGWLERAAKQTRFYLFGIMQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>CP026473.1|AUY29224.1|2261759_2262428_+|hypothetical-protein
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQQNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>CP026473.1|AUY29223.1|2261057_2261696_+|hypothetical-protein
MNHRDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSAAGQLVARAVFLSPPYSVAEEELSVLLESIKQNGDYADIACMTGSQDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>CP026473.1|AUY29222.1|2258942_2261045_+|Aldehyde-ferredoxin-oxidoreductase
MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKELFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIHWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPV
>CP026473.1|AUY29221.1|2258295_2258922_+|hypothetical-protein
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>CP026473.1|AUY29220.1|2257630_2257840_+|hypothetical-protein
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>CP026473.1|AUY29219.1|2255115_2255352_-|Major-outer-membrane-lipoprotein
MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQLSNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK
>CP026473.1|AUY29229.1|2266645_2267902_+|hypothetical-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDQGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDGVTFIVGNINLNGGKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITDASRQTLCNALKLQPDEDGIGATLQPA
>CP026473.1|AUY29230.1|2267942_2269316_-|Multidrug-resistance-efflux-pump-MdtK
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSVIILQRASR
>CP026473.1|AUY29231.1|2269530_2270172_+|Riboflavin-synthase-alpha-subunit
MFTGIVQGTVKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA
>CP026473.1|AUY29232.1|2270211_2271360_-|Cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIASARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>CP026473.1|AUY29233.1|2271650_2272862_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQVIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNHGNAEVAHSESH
>CP026473.1|AUY29234.1|2272974_2273907_+|HTH-type-transcriptional-regulator-YdhB
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRVVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVVLELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>CP026473.1|AUY29235.1|2273903_2274929_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>CP026473.1|AUY29236.1|2275482_2276652_+|Inner-membrane-transport-protein-ydhP
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>CP026473.1|AUY29237.1|2276797_2277379_-|Superoxide-dismutase
MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA
>CP026473.1|AUY29238.1|2277506_2278322_-|Endopeptidase
MARINRISITLCALLFTTLPLTPMAHASKQARESSATTHITKKADKKKSTATTKKTQKTAKKAASKSTTKSKTASSVKKSSITASKNAKTRSKHAVNKTASASFTEKCTKRKGYKSHCVKVKNAASGTLADAHKAKVQKATKVAMNKLMQQIGKPYRWGGSSPRTGFDCSGLVYYAYKDLVKIRIPRTANEMYHLRDAAPIERSELKNGDLVFFRTQGRGTADHVGVYVGNGKFIQSPRTGQEIQITSLSEDYWQRHYVGARRVMTPKTLR

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Crispr_ID: CP026473_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026473_9

3292194-3292338

Orphan

Consensus_repeat	Method
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026473_9

>merge|CP026473|9|3292194-3292338|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGCTGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTCGTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

>CP026473|9|8|3292194-3292338|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	TGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTC
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

Protein	Signature genes	Signature genes Name	Protein_function
CP026473.1\|AUY30146.1\|3287222_3287405_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|284449
CP026473.1\|AUY30154.1\|3296314_3297367_-\|PrpF-family-protein	unknown	unknown	gnl\|CDD\|380230
CP026473.1\|AUY30159.1\|3301574_3302264_-\|Molybdate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|181841
CP026473.1\|AUY30148.1\|3287645_3287861_+\|hypothetical-protein	unknown	unknown	unknown
CP026473.1\|AUY30153.1\|3294805_3296239_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|279307
CP026473.1\|AUY30150.1\|3289236_3289404_+\|hypothetical-protein	unknown	unknown	unknown
CP026473.1\|AUY30149.1\|3288391_3288541_-\|hypothetical-protein	unknown	unknown	unknown
CP026473.1\|AUY30145.1\|3286545_3287226_+\|Exonuclease	unknown	unknown	gnl\|CDD\|378216
CP026473.1\|AUY30155.1\|3297550_3298504_+\|putative-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176131
CP026473.1\|AUY30143.1\|3285461_3285758_+\|Host-nuclease-inhibitor-protein-Gam	unknown	unknown	gnl\|CDD\|368728
CP026473.1\|AUY30160.1\|3302263_3303037_-\|Molybdate-transporter	unknown	unknown	gnl\|CDD\|182641
CP026473.1\|AUY30158.1\|3300513_3301572_-\|Molybdenum-import-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|182993
CP026473.1\|AUY30152.1\|3292361_3294623_-\|aconitate-hydratase	unknown	unknown	gnl\|CDD\|183125
CP026473.1\|AUY30151.1\|3290844_3292128_+\|pectinesterase	unknown	unknown	gnl\|CDD\|236709
CP026473.1\|AUY30157.1\|3299694_3300513_+\|Cof-like-hydrolase	unknown	unknown	gnl\|CDD\|182523
CP026473.1\|AUY30147.1\|3287377_3287569_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369224
CP026473.1\|AUY30144.1\|3285763_3286549_+\|phage-recombination-protein-Bet	unknown	unknown	gnl\|CDD\|273871
CP026473.1\|AUY30142.1\|3285179_3285386_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236900
CP026473.1\|AUY30161.1\|3303203_3303353_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371231
CP026473.1\|AUY30156.1\|3298544_3299540_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|182912

Protein	Function_ID	Function_description	E-value
CP026473.1\|AUY30146.1\|3287222_3287405_+\|hypothetical-protein	gnl\|CDD\|284449	pfam07026, DUF1317, Protein of unknown function (DUF1317). This family consists of several hypothetical bacterial and phage proteins of around 60 residues in length. The function of this family is unknown.	8.0633e-35
CP026473.1\|AUY30159.1\|3301574_3302264_-\|Molybdate-ABC-transporter-permease	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	2.41762e-146
CP026473.1\|AUY30153.1\|3294805_3296239_-\|hypothetical-protein	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	0
CP026473.1\|AUY30147.1\|3287377_3287569_+\|hypothetical-protein	gnl\|CDD\|369224	pfam07131, DUF1382, Protein of unknown function (DUF1382). This family consists of several hypothetical Escherichia coli and bacteriophage lambda-like proteins of around 60 residues in length. The function of this family is unknown. Structural modelling suggests this domain may bind nucleic acids.	8.16312e-23
CP026473.1\|AUY30145.1\|3286545_3287226_+\|Exonuclease	gnl\|CDD\|378216	pfam09588, YqaJ, YqaJ-like viral recombinase domain. This protein family is found in many different bacterial species but is of viral origin. The protein forms an oligomer and functions as a processive alkaline exonuclease that digests linear double-stranded DNA in a Mg(2+)-dependent reaction, It has a preference for 5'-phosphorylated DNA ends. It thus forms part of the two-component SynExo viral recombinase functional unit.	2.98824e-27
CP026473.1\|AUY30155.1\|3297550_3298504_+\|putative-DNA-binding-transcriptional-regulator	gnl\|CDD\|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.09679e-82
CP026473.1\|AUY30143.1\|3285461_3285758_+\|Host-nuclease-inhibitor-protein-Gam	gnl\|CDD\|368728	pfam06064, Gam, Host-nuclease inhibitor protein Gam. The Gam protein inhibits RecBCD nuclease and is found in both bacteria and bacteriophage.	8.40476e-53
CP026473.1\|AUY30160.1\|3302263_3303037_-\|Molybdate-transporter	gnl\|CDD\|182641	PRK10677, modA, molybdate transporter periplasmic protein; Provisional.	0
CP026473.1\|AUY30158.1\|3300513_3301572_-\|Molybdenum-import-ATP-binding-protein-ModC	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0
CP026473.1\|AUY30152.1\|3292361_3294623_-\|aconitate-hydratase	gnl\|CDD\|183125	PRK11413, PRK11413, putative hydratase; Provisional.	0
CP026473.1\|AUY30151.1\|3290844_3292128_+\|pectinesterase	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
CP026473.1\|AUY30157.1\|3299694_3300513_+\|Cof-like-hydrolase	gnl\|CDD\|182523	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional.	0
CP026473.1\|AUY30142.1\|3285179_3285386_+\|hypothetical-protein	gnl\|CDD\|236900	PRK11354, kil, FtsZ inhibitor protein; Reviewed.	6.0586e-14
CP026473.1\|AUY30144.1\|3285763_3286549_+\|phage-recombination-protein-Bet	gnl\|CDD\|273871	TIGR01913, Uncharacterized_protein_UU154, phage recombination protein Bet. This model represents the phage recombination protein Bet from a number of phage, including phage lambda. All members of this family are found in phage genomes or in putative prophage regions of bacterial genomes. [Mobile and extrachromosomal element functions, Prophage functions].	1.45393e-64
CP026473.1\|AUY30154.1\|3296314_3297367_-\|PrpF-family-protein	gnl\|CDD\|380230	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase.	0
CP026473.1\|AUY30161.1\|3303203_3303353_-\|hypothetical-protein	gnl\|CDD\|371231	pfam10766, AcrZ, Multidrug efflux pump-associated protein AcrZ. AcrZ is associated with the AcrA-TolC multidrug efflux pump, it may enhance the ability of the pump to recognize and export certain substrates.	1.04381e-17
CP026473.1\|AUY30156.1\|3298544_3299540_-\|6-phosphogluconolactonase	gnl\|CDD\|182912	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional.	0

>CP026473.1|AUY30151.1|3290844_3292128_+|pectinesterase
MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK
>CP026473.1|AUY30150.1|3289236_3289404_+|hypothetical-protein
MHFRVTGEWNGEPFNRVIEAENISDCYDHWMLWAQIAHADVTNIRIEELKEHQAA
>CP026473.1|AUY30149.1|3288391_3288541_-|hypothetical-protein
MDDPDLHENIRICYPYGNYEYDNIIYVEKKINILGAVVTYAQTARDDTE
>CP026473.1|AUY30148.1|3287645_3287861_+|hypothetical-protein
MTPQQENALRSIARQANSEIKKARQQFPDKNVDDICRSVLKKHRETVTLMGFTPTHLSLAIGMLNGVFKER
>CP026473.1|AUY30147.1|3287377_3287569_+|hypothetical-protein
MHKASPVELRTSIEMAHSLAQIGVRFVPIPVETDEEFHTLAAFLSQKLEMMVAKAEADERDQV
>CP026473.1|AUY30146.1|3287222_3287405_+|hypothetical-protein
MTHPHDNIRVGAITFVYSVTKRGWVFPGLSVIRNPLKAQRLAEEINNKRGAVCTKHLPLS
>CP026473.1|AUY30145.1|3286545_3287226_+|Exonuclease
MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSSVNITESPIIYRDENMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKDAWYFANYDPRMKREGLHYVVVERDEKYMASFDEMVPEFIEKMDEALAEIGFVFGEQWR
>CP026473.1|AUY30144.1|3285763_3286549_+|phage-recombination-protein-Bet
MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQFIALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWSRIINENQQFDGMDFEQDNESCTCRIYRKDRNHPICVTEWMDECRREPFKTREGREITGPWQSHPKRMLRHKAMIQCARLAFGFAGIYDKDEAERIVENTAYTAERQPERDITPVNDETMQEINTLLIALDKTWDDDLLPLCSQIFRRDIRASSELTQAEAVKALGFLKQKATEQKVAA
>CP026473.1|AUY30143.1|3285461_3285758_+|Host-nuclease-inhibitor-protein-Gam
MNAYYIQDRLEAQSWARHYQQIAREEKEAELADDMEKGLPQHLFESLCIDHLQRHGASKKAITRAFDDDVEFQERMAEHIRYMVETIAHHQVDIDSEV
>CP026473.1|AUY30142.1|3285179_3285386_+|hypothetical-protein
MVHQHYGTQTVNRGAVMPGMLVKHKDGTWTASANLRGRLYLHRGIERTYTRDLLVEVFLDGRGNGLNH
>CP026473.1|AUY30152.1|3292361_3294623_-|aconitate-hydratase
MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAQKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYKIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAQKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMGSLTAEEREIIKAGSLINFNKNRQM
>CP026473.1|AUY30153.1|3294805_3296239_-|hypothetical-protein
MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIVGLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAAFVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSVAVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISWGGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLGVFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGIIGLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAMLPVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGAVLTILTFLVHITLGVWWWNMLIGWNML
>CP026473.1|AUY30154.1|3296314_3297367_-|PrpF-family-protein
MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIGGGNPLTSKVAIISRSSDLRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGAFAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVALTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRASVIRTTRKIFSGEVYLP
>CP026473.1|AUY30155.1|3297550_3298504_+|putative-DNA-binding-transcriptional-regulator
MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDWFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
>CP026473.1|AUY30156.1|3298544_3299540_-|6-phosphogluconolactonase
MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYSIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
>CP026473.1|AUY30157.1|3299694_3300513_+|Cof-like-hydrolase
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
>CP026473.1|AUY30158.1|3300513_3301572_-|Molybdenum-import-ATP-binding-protein-ModC
MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAISGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMSKSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLDIPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWGSSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELAIKPGLWLYAQIKSVSITA
>CP026473.1|AUY30159.1|3301574_3302264_-|Molybdate-ABC-transporter-permease
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>CP026473.1|AUY30160.1|3302263_3303037_-|Molybdate-transporter
MARKWLNLFAGAALSFAVAGNALADEGKITVFAAASLTNAMQDIATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTATRQTLLGNSLVVVAPKASEQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKLGAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVAIFPEDSHKKVEYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTTK
>CP026473.1|AUY30161.1|3303203_3303353_-|hypothetical-protein
MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH

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Crispr_ID: CP026473_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026473_10

3788191-3788344

Orphan

Consensus_repeat	Method
CGCCTTATCCGGCCTACCGATCCAGCACAGGTTTGTAGGCATGATAAGACGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026473_10

>merge|CP026473|10|3788191-3788344|CRISPRCasFinder
CGCCTTATCCGGCCTACCGATCCAGCACAGGTTTGTAGGCATGATAAGACGCGTCAGCGTCGCATCAGGCATCTGCGCATAACCGCCGGATGCGGCGTAAACGCCTTATCCGGCCTACCGATCCGGCACAGGTTTGTAGGCATGATAAGACGCG

>CP026473|10|9|3788191-3788344|CRISPRCasFinder
CGCCTTATCCGGCCTACCGATCCAGCACAGGTTTGTAGGCATGATAAGACGCG	TCAGCGTCGCATCAGGCATCTGCGCATAACCGCCGGATGCGGCGTAAA
CGCCTTATCCGGCCTACCGATCCGGCACAGGTTTGTAGGCATGATAAGACGCG

Protein	Signature genes	Signature genes Name	Protein_function
CP026473.1\|AUY30576.1\|3797921_3798371_-\|hypothetical-protein	unknown	unknown	unknown
CP026473.1\|AUY30563.1\|3783138_3783396_-\|Peptide-chain-release-factor-like-protein	unknown	unknown	gnl\|CDD\|181271
CP026473.1\|AUY30564.1\|3783438_3783705_-\|release-factor-H-coupled-RctB-family-protein	unknown	unknown	gnl\|CDD\|181972
CP026473.1\|AUY30565.1\|3784011_3784389_-\|Acetyltransferase-family-protein	unknown	unknown	gnl\|CDD\|182099
CP026473.1\|AUY30569.1\|3790096_3790837_+\|transpepdiase	unknown	unknown	gnl\|CDD\|225577
CP026473.1\|AUY30560.1\|3779569_3780814_-\|Esterase-FrsA	unknown	unknown	gnl\|CDD\|235337
CP026473.1\|AUY30570.1\|3790807_3791575_-\|class-II-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|372525
CP026473.1\|AUY30558.1\|3778016_3779072_+\|Outer-membrane-pore-protein-E	unknown	unknown	gnl\|CDD\|182275
CP026473.1\|AUY30568.1\|3789046_3789805_-\|Lipoprotein-YafL	unknown	unknown	gnl\|CDD\|223862
CP026473.1\|AUY30571.1\|3791780_3792359_-\|D-sedoheptulose-7-phosphate-isomerase	unknown	unknown	gnl\|CDD\|179012
CP026473.1\|AUY30572.1\|3792598_3795043_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|236528
CP026473.1\|AUY30574.1\|3795712_3796483_+\|YafV-protein	unknown	unknown	gnl\|CDD\|182461
CP026473.1\|AUY30573.1\|3795085_3795559_-\|vertebrate-lysozyme-inhibitor	unknown	unknown	gnl\|CDD\|182187
CP026473.1\|AUY30566.1\|3784460_3785516_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
CP026473.1\|AUY30577.1\|3801350_3803273_+\|Type-VI-secretion-protein-IcmF	unknown	unknown	gnl\|CDD\|226054
CP026473.1\|AUY30562.1\|3781624_3783082_+\|Aminoacyl-histidine-dipeptidase	unknown	unknown	gnl\|CDD\|184986
CP026473.1\|AUY30575.1\|3796524_3797568_-\|Transposase,-IS4-family	unknown	unknown	gnl\|CDD\|227720
CP026473.1\|AUY30567.1\|3786316_3788056_+\|Flagellar-biosynthesis-protein-FlhA	unknown	unknown	gnl\|CDD\|224217
CP026473.1\|AUY30559.1\|3779110_3779512_-\|Sigma-factor-binding-protein-Crl	unknown	unknown	gnl\|CDD\|182882
CP026473.1\|AUY30561.1\|3780905_3781364_-\|Xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|236395

Protein	Function_ID	Function_description	E-value
CP026473.1\|AUY30563.1\|3783138_3783396_-\|Peptide-chain-release-factor-like-protein	gnl\|CDD\|181271	PRK08179, prfH, peptide chain release factor-like protein; Reviewed.	5.8209e-24
CP026473.1\|AUY30564.1\|3783438_3783705_-\|release-factor-H-coupled-RctB-family-protein	gnl\|CDD\|181972	PRK09588, PRK09588, hypothetical protein; Reviewed.	1.93527e-42
CP026473.1\|AUY30565.1\|3784011_3784389_-\|Acetyltransferase-family-protein	gnl\|CDD\|182099	PRK09831, PRK09831, GNAT family N-acetyltransferase.	1.02165e-85
CP026473.1\|AUY30569.1\|3790096_3790837_+\|transpepdiase	gnl\|CDD\|225577	COG3034, COG3034, Uncharacterized protein conserved in bacteria [Function unknown].	1.07529e-116
CP026473.1\|AUY30560.1\|3779569_3780814_-\|Esterase-FrsA	gnl\|CDD\|235337	PRK05077, frsA, esterase FrsA.	0
CP026473.1\|AUY30570.1\|3790807_3791575_-\|class-II-glutamine-amidotransferase	gnl\|CDD\|372525	pfam13230, GATase_4, Glutamine amidotransferases class-II. This family captures members that are not found in pfam00310.	8.29603e-146
CP026473.1\|AUY30558.1\|3778016_3779072_+\|Outer-membrane-pore-protein-E	gnl\|CDD\|182275	PRK10159, PRK10159, phosphoporin PhoE.	0
CP026473.1\|AUY30568.1\|3789046_3789805_-\|Lipoprotein-YafL	gnl\|CDD\|223862	COG0791, Spr, Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane].	3.3314e-41
CP026473.1\|AUY30571.1\|3791780_3792359_-\|D-sedoheptulose-7-phosphate-isomerase	gnl\|CDD\|179012	PRK00414, gmhA, D-sedoheptulose 7-phosphate isomerase.	1.61173e-142
CP026473.1\|AUY30572.1\|3792598_3795043_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|236528	PRK09463, fadE, acyl-CoA dehydrogenase; Reviewed.	0
CP026473.1\|AUY30574.1\|3795712_3796483_+\|YafV-protein	gnl\|CDD\|182461	PRK10438, PRK10438, C-N hydrolase family amidase; Provisional.	0
CP026473.1\|AUY30573.1\|3795085_3795559_-\|vertebrate-lysozyme-inhibitor	gnl\|CDD\|182187	PRK09993, PRK09993, C-lysozyme inhibitor; Provisional.	9.39999e-93
CP026473.1\|AUY30566.1\|3784460_3785516_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
CP026473.1\|AUY30577.1\|3801350_3803273_+\|Type-VI-secretion-protein-IcmF	gnl\|CDD\|226054	COG3523, IcmF, Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and vesicular transport].	0
CP026473.1\|AUY30562.1\|3781624_3783082_+\|Aminoacyl-histidine-dipeptidase	gnl\|CDD\|184986	PRK15026, PRK15026, aminoacyl-histidine dipeptidase; Provisional.	0
CP026473.1\|AUY30575.1\|3796524_3797568_-\|Transposase,-IS4-family	gnl\|CDD\|227720	COG5433, COG5433, Transposase [DNA replication, recombination, and repair].	1.18125e-32
CP026473.1\|AUY30567.1\|3786316_3788056_+\|Flagellar-biosynthesis-protein-FlhA	gnl\|CDD\|224217	COG1298, FlhA, Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion].	0
CP026473.1\|AUY30559.1\|3779110_3779512_-\|Sigma-factor-binding-protein-Crl	gnl\|CDD\|182882	PRK10984, PRK10984, sigma factor-binding protein Crl.	1.11584e-87
CP026473.1\|AUY30561.1\|3780905_3781364_-\|Xanthine-phosphoribosyltransferase	gnl\|CDD\|236395	PRK09177, PRK09177, xanthine-guanine phosphoribosyltransferase; Validated.	5.05624e-113

>CP026473.1|AUY30567.1|3786316_3788056_+|Flagellar-biosynthesis-protein-FlhA
MLSRSDLLTLLTINFIVVTKGAERISEVSARFTLDAMPGKQMAIDADLNAGLINQAQAQTRRKDVASEADFYGAMDGASKFVRGDAIAGMMILAINLIGGVCIGIFKYNLSADAAFQQYVLMTIGDGLVAQIPSLLLSTAAAIIVTRISDNGDITHDVRHQLLASPSVLYTATGIMFVLAVVPGMPHLPFLLFSALLGFTGWRMSKRPQAAEAEEKSLETLTRTITETSEQQVSWETIPLIEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQVISDGNGVLLPEIRIRENFRLKPSQYAIFINGIKADEADIPADKLMALPSSETYGEIDGVLGNDPAYGMPVTWIQPAQKAKALNMGYQVIDSASVIATHVNKIVRSYIPDLFSYDDITQLHNRLSSMAPRLAEDLSAALNYSQLLKVYRALLTEGVSLRDIVTIATVLVASSAVTKDHILLAADVRLALRRSITHPFVRKQELTVYTLNNELENLLTNVVNQAQQGGKVMLDSVPVDPNMLNQFQSTMPQVKEQMKAAGKDPVLLVPPQLRPLLARYARLFAPGLHVLSYNEVPDELELKIMGALM
>CP026473.1|AUY30566.1|3784460_3785516_-|DNA-polymerase-IV
MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFNELHLTASAGVAPVKFLAKIASDMNKPNGQFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVILLKRFGKFGRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGLHVTLLDPQMERQLVLGL
>CP026473.1|AUY30565.1|3784011_3784389_-|Acetyltransferase-family-protein
MMTASQHYSPQQIAAWAQIDESRWKEKLAKSQVRVAVINAQPVGFISRIERHIDMLFVDPEYTRRGVASALLKPLIKSESELTVDASITAKPFFERYGFQIVKQQHVECRGAWFTNFYMRYKPQH
>CP026473.1|AUY30564.1|3783438_3783705_-|release-factor-H-coupled-RctB-family-protein
MEWYMGKYIRPLSDAVFTIASDDLWIESLAIQQLHTTANLPNMQRVVGMPDLHPGRGYPIGAAFFSVGRFYPARRRGNGAGNRNGPLL
>CP026473.1|AUY30563.1|3783138_3783396_-|Peptide-chain-release-factor-like-protein
MGIKRKLVRHYSVDLSESVSVSSWAQKLVSGHANKRLARLLIAWKLEQQQQENSAALKSQRRMFHHQIERGNPRRTFTGMAFIEG
>CP026473.1|AUY30562.1|3781624_3783082_+|Aminoacyl-histidine-dipeptidase
MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKGFHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDGEWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWLQADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGGEIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDALKSLVNTYQDILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRNSDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEAKGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIGPTITGPHSPDEQVHIKSVGHYWTLLTELLKEIPAK
>CP026473.1|AUY30561.1|3780905_3781364_-|Xanthine-phosphoribosyltransferase
MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDNYVVDIPQDTWIEQPWDMGVVFVPPISGR
>CP026473.1|AUY30560.1|3779569_3780814_-|Esterase-FrsA
MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTIPHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEAAQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDDALRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDKGLQEITGWIEKRLC
>CP026473.1|AUY30559.1|3779110_3779512_-|Sigma-factor-binding-protein-Crl
MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNVKPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLREFHEKLRELLTTLNLKLEPADDFRDEPVKLTA
>CP026473.1|AUY30558.1|3778016_3779072_+|Outer-membrane-pore-protein-E
MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYMSDNDSKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGLKYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFFGVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQNLQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQFDFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNKLNINNDDIVAVGMTYQF
>CP026473.1|AUY30568.1|3789046_3789805_-|Lipoprotein-YafL
MSFMSSFLLGRFLHPGVFSLCVLLPLFASATTSHISFSYAARQRMQNRARLLKQYQTHLKKQASYIVEGNAESRRALRQHNREQIKQHPEWFPAPLKASDRRWQALAENNHFLSSDHLHNITEVAIHRLEQQLGKPYVWGGTRPDQGFDCSGLVFYAYNKILEAKLPRTANEMYHYHRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDGQFIESPRTGENIRVSRLAEPFWQDHFLGARRILTEETIL
>CP026473.1|AUY30569.1|3790096_3790837_+|transpepdiase
MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPVYIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQLKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTGALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVNGRYVVSKPLSHEVVQPQLASNYTLPEAK
>CP026473.1|AUY30570.1|3790807_3791575_-|class-II-glutamine-amidotransferase
MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGKGCRTFKDPQPSFNSPIAKLVQDYPIKSCSVVAHIRQANRGEVALENTHPFTRELWGRNWTYAHNGQLTGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMAAVFKYIASLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTTPNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGERVV
>CP026473.1|AUY30571.1|3791780_3792359_-|D-sedoheptulose-7-phosphate-isomerase
MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVK
>CP026473.1|AUY30572.1|3792598_3795043_+|acyl-CoA-dehydrogenase
MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWSAWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDLFQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLKEHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGTDEQKNHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWNKRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVPFQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALATGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAIVKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMIFGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSSTPTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAVLKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRHYLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQRICKELGKNLPFTRLDELAHNALAKGLIDKDEAAILVKAEESRLCSINVDDFDPEELATKPVKLPEKVRKVEAA
>CP026473.1|AUY30573.1|3795085_3795559_-|vertebrate-lysozyme-inhibitor
MGRISSGGMMFKAITTVAALVIATSAMAQDDLTISSLAKGETTKAAFNQMVQGHKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEKSNQMTGLFSTIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK
>CP026473.1|AUY30574.1|3795712_3796483_+|YafV-protein
MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMFTSGFAMEAAASSLAQNDVVNWMTAKAQQCNALIAGSVALQTESGSVNRFLLVEPGGTVHFYDKRHLFRMADEHLHYKAGNARVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAIYVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIATADAHQATRIDAELSMVALREYREKFPAWQDADEFRLR
>CP026473.1|AUY30575.1|3796524_3797568_-|Transposase,-IS4-family
MTIFAVISGAESWEDIEDFGETHLDFLKQYGDFENGIPVHDTIARVVSCISPAKFHECFINWMRDCHSSDDKDVIAIDGKTLRHSYDKSRRRGAIHVISAFSTMHSLVIGQIRTDEKSNEITAIPELLNMLDIKGKIITTDAMGCQKDIAEKIQKQGGDYLFAVKGNQGRLNKAFEEKFPLKELNNPEHDSYAMSEKSHGREEIRLHIVCDVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKEPEMTVRYYISSADLTAEKFATAIRNHWHVENKLHWRLDVVMNEDDCKIRRGNAAELFSGIRHIAINILTNDKVFKAGLRRKMRKAAMDRNYLASVLAESGLS
>CP026473.1|AUY30576.1|3797921_3798371_-|hypothetical-protein
MMKYLMVLLSLFSGSVLGMGRVNELCGIDSVKTIEIINLPSYVTTLVPLSKEGLNEIYRYKVVVNEISDLYAGKIIDLLQMKYFRKEKYNNIRWGVSIISKGNNKCEIYFDAFGECGSVNGINVCFEKNEMIGWIKKEIPLLSQKIGGL
>CP026473.1|AUY30577.1|3801350_3803273_+|Type-VI-secretion-protein-IcmF
MLPSACSFFTTRFRPPSPSVYLPSLFNGLVKAMNAAPPESEEKLAVLRVMRMLEDKSGRNNQVVKQYMAKRWSEKFHGQRDIQAQLMSHLDYALAHTDWHAERQAGDGDAISRWTPYDKPVVSAQKELSKLPVYQRVYQSLKTRALGVLPADLNLRDQVGPTFDQVFTSADDNKLVVPQFLTRYGLQSYFVKQRDELVELTAMDSWVLNLTRSVKYSDADRAEIQRQLTEQYISDYTATWRAGMDNLNIRNFESIGQLTGALEQVISGDQPLQRALTVLRDNTQPGVFSEKLSAKEREEALAEPDYQLLTRLGHEFAPENSTLAVQKDKESTMQAVYQQLTELHRYLLAIQNAPVPGKSALKAVQLRLDQNSSDPIFATRQMAKTLPAPLNRWVGRLTDQAWHVVMVEAVHYMEVDWRDSVVKPFNEQLANNYPFNPRSAQDASLDAFERFFKPDGILDTFYQQNLKLFIDNDLSLEDGDNNVIIREDIIAQLETAQKIRDIFFSKQNGLGASFAVETVSLSGNKRRSVLNLDGQLVDYSQGRNYTAHLVWPNNMREGNESKLTLIGTSGNAPRSISFSGPWAQFRLFGAGQLTGVQDGNFTVRFSVDGGAMTYRVHTDTEDNPFSGGLFSQFGLSDTLY

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Crispr_ID: CP026473_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026473_11

4001637-4001769

Orphan

Consensus_repeat	Method
ATCACCAATATTGAAAA	PILER-CR

2 spacers

The CRISPR arrays of CP026473_11

>merge|CP026473|11|4001637-4001769|PILER-CR
ATCACCAATATTGAAAATGTCACACGCAGATAAATCCAACTTTCAATATTGTTAAGTTCCTCACCAATATTGAAAACATGGCGTAGCAAAAAGAAATTTTCAATATTGCTTTATGGATCACCAATATTGAAAG

>CP026473|11|4|4001637-4001769|PILER-CR
ATCACCAATATTGAAAA	TGTCACACGCAGATAAATCCAACTTTCAATATTGTTAAGTTC
CTCACCAATATTGAAAA	CATGGCGTAGCAAAAAGAAATTTTCAATATTGCTTTATGG
ATCACCAATATTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
CP026473.1\|AUY30735.1\|3992341_3992719_+\|Protein-ApaG	unknown	unknown	gnl\|CDD\|180098
CP026473.1\|AUY30746.1\|4003564_4004707_+\|Crotonobetainyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|179566
CP026473.1\|AUY30752.1\|4009718_4009937_+\|hypothetical-protein	unknown	unknown	unknown
CP026473.1\|AUY30736.1\|3992725_3993568_+\|Bis(5'-nucleosyl)-tetraphosphatase	unknown	unknown	gnl\|CDD\|273208
CP026473.1\|AUY30747.1\|4004835_4006053_+\|L-carnitine-CoA-transferase	unknown	unknown	gnl\|CDD\|179589
CP026473.1\|AUY30749.1\|4007788_4008574_+\|Carnitinyl-CoA-dehydratase	unknown	unknown	gnl\|CDD\|179599
CP026473.1\|AUY30738.1\|3994316_3996179_-\|Glutathione-regulated-potassium-efflux-system-protein-KefC	unknown	unknown	gnl\|CDD\|235131
CP026473.1\|AUY30753.1\|4009944_4013166_-\|Carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|235393
CP026473.1\|AUY30745.1\|4002019_4003534_+\|L-carnitine/gamma-butyrobetaine-antiporter	unknown	unknown	gnl\|CDD\|179568
CP026473.1\|AUY30741.1\|3998198_3998486_-\|Ferredoxin-like-protein-FixX	unknown	unknown	gnl\|CDD\|185346
CP026473.1\|AUY30751.1\|4009288_4009684_-\|Transcriptional-activatory-protein-CaiF	unknown	unknown	gnl\|CDD\|183154
CP026473.1\|AUY30754.1\|4013183_4014332_-\|Carbamoyl-phosphate-synthase-small-chain	unknown	unknown	gnl\|CDD\|237139
CP026473.1\|AUY30740.1\|3996809_3998141_-\|Putative-metabolite-transport-protein-yaaU	unknown	unknown	gnl\|CDD\|340874
CP026473.1\|AUY30742.1\|3998482_3999769_-\|Protein-fixC	unknown	unknown	gnl\|CDD\|182273
CP026473.1\|AUY30739.1\|3996171_3996702_-\|Glutathione-regulated-potassium-efflux-system-ancillary-protein-KefF	unknown	unknown	gnl\|CDD\|234852
CP026473.1\|AUY30744.1\|4000775_4001546_-\|Protein-FixA	unknown	unknown	gnl\|CDD\|179569
CP026473.1\|AUY30737.1\|3993645_3994236_-\|Dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714
CP026473.1\|AUY30750.1\|4008579_4009170_+\|Carnitine-operon-protein-CaiE	unknown	unknown	gnl\|CDD\|184189
CP026473.1\|AUY30748.1\|4006126_4007680_+\|putative-crotonobetaine/carnitine-CoA-ligase	unknown	unknown	gnl\|CDD\|181195
CP026473.1\|AUY30743.1\|3999819_4000761_-\|Protein-FixB	unknown	unknown	gnl\|CDD\|235120

Protein	Function_ID	Function_description	E-value
CP026473.1\|AUY30735.1\|3992341_3992719_+\|Protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	3.63315e-76
CP026473.1\|AUY30746.1\|4003564_4004707_+\|Crotonobetainyl-CoA-dehydrogenase	gnl\|CDD\|179566	PRK03354, PRK03354, crotonobetainyl-CoA dehydrogenase; Validated.	0
CP026473.1\|AUY30736.1\|3992725_3993568_+\|Bis(5'-nucleosyl)-tetraphosphatase	gnl\|CDD\|273208	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical). Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a regulatory metabolite of stress conditions. It is hydrolyzed to two ADP by this enzyme. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase. [Cellular processes, Adaptations to atypical conditions].	0
CP026473.1\|AUY30747.1\|4004835_4006053_+\|L-carnitine-CoA-transferase	gnl\|CDD\|179589	PRK03525, PRK03525, L-carnitine CoA-transferase.	0
CP026473.1\|AUY30749.1\|4007788_4008574_+\|Carnitinyl-CoA-dehydratase	gnl\|CDD\|179599	PRK03580, PRK03580, crotonobetainyl-CoA hydratase.	1.51953e-178
CP026473.1\|AUY30738.1\|3994316_3996179_-\|Glutathione-regulated-potassium-efflux-system-protein-KefC	gnl\|CDD\|235131	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional.	0
CP026473.1\|AUY30753.1\|4009944_4013166_-\|Carbamoyl-phosphate-synthase-large-subunit	gnl\|CDD\|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
CP026473.1\|AUY30745.1\|4002019_4003534_+\|L-carnitine/gamma-butyrobetaine-antiporter	gnl\|CDD\|179568	PRK03356, PRK03356, L-carnitine/gamma-butyrobetaine antiport BCCT transporter.	0
CP026473.1\|AUY30741.1\|3998198_3998486_-\|Ferredoxin-like-protein-FixX	gnl\|CDD\|185346	PRK15449, PRK15449, ferredoxin-like protein FixX; Provisional.	2.23442e-69
CP026473.1\|AUY30751.1\|4009288_4009684_-\|Transcriptional-activatory-protein-CaiF	gnl\|CDD\|183154	PRK11476, PRK11476, carnitine metabolism transcriptional regulator CaiF.	1.42176e-74
CP026473.1\|AUY30754.1\|4013183_4014332_-\|Carbamoyl-phosphate-synthase-small-chain	gnl\|CDD\|237139	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit.	0
CP026473.1\|AUY30740.1\|3996809_3998141_-\|Putative-metabolite-transport-protein-yaaU	gnl\|CDD\|340874	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily. This family is composed of metazoan synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters including those that transport inorganic phosphate (Pht), aromatic compounds (PcaK and related proteins), proline/betaine (ProP), alpha-ketoglutarate (KgtP), citrate (CitA), shikimate (ShiA), and cis,cis-muconate (MucK), among others. SV2 is a transporter-like protein that serves as the receptor for botulinum neurotoxin A (BoNT/A), one of seven neurotoxins produced by the bacterium Clostridium botulinum. BoNT/A blocks neurotransmitter release by cleaving synaptosome-associated protein of 25 kD (SNAP-25) within presynaptic nerve terminals. Also included in this family is synaptic vesicle 2 (SV2)-related protein (SVOP) and similar proteins. SVOP is a transporter-like nucleotide binding protein that localizes to neurotransmitter-containing vesicles. The SV2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.4298e-59
CP026473.1\|AUY30742.1\|3998482_3999769_-\|Protein-fixC	gnl\|CDD\|182273	PRK10157, PRK10157, putative oxidoreductase FixC; Provisional.	0
CP026473.1\|AUY30739.1\|3996171_3996702_-\|Glutathione-regulated-potassium-efflux-system-ancillary-protein-KefF	gnl\|CDD\|234852	PRK00871, PRK00871, glutathione-regulated potassium-efflux system oxidoreductase KefF.	2.99389e-133
CP026473.1\|AUY30744.1\|4000775_4001546_-\|Protein-FixA	gnl\|CDD\|179569	PRK03359, PRK03359, putative electron transfer flavoprotein FixA; Reviewed.	6.8619e-170
CP026473.1\|AUY30737.1\|3993645_3994236_-\|Dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.12644e-127
CP026473.1\|AUY30750.1\|4008579_4009170_+\|Carnitine-operon-protein-CaiE	gnl\|CDD\|184189	PRK13627, PRK13627, carnitine operon protein CaiE; Provisional.	4.44962e-142
CP026473.1\|AUY30748.1\|4006126_4007680_+\|putative-crotonobetaine/carnitine-CoA-ligase	gnl\|CDD\|181195	PRK08008, caiC, putative crotonobetaine/carnitine-CoA ligase; Validated.	0
CP026473.1\|AUY30743.1\|3999819_4000761_-\|Protein-FixB	gnl\|CDD\|235120	PRK03363, fixB, electron transfer flavoprotein subunit alpha/FixB family protein.	0

>CP026473.1|AUY30744.1|4000775_4001546_-|Protein-FixA
MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAWSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
>CP026473.1|AUY30743.1|3999819_4000761_-|Protein-FixB
MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGAQAIQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR
>CP026473.1|AUY30742.1|3998482_3999769_-|Protein-fixC
MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNVTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRSYSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILADGVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTDGLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEYSAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSAMKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFTIDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL
>CP026473.1|AUY30741.1|3998198_3998486_-|Ferredoxin-like-protein-FixX
MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQVLELLVKACPAGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG
>CP026473.1|AUY30740.1|3996809_3998141_-|Putative-metabolite-transport-protein-yaaU
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADLVGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG
>CP026473.1|AUY30739.1|3996171_3996702_-|Glutathione-regulated-potassium-efflux-system-ancillary-protein-KefF
MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQEAHHG
>CP026473.1|AUY30738.1|3994316_3996179_-|Glutathione-regulated-potassium-efflux-system-protein-KefC
MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGCGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREADEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS
>CP026473.1|AUY30737.1|3993645_3994236_-|Dihydrofolate-reductase
MDSPAEYKIFLNIILAPVDDGLRFTYSGDNFFYREISMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
>CP026473.1|AUY30736.1|3992725_3993568_+|Bis(5'-nucleosyl)-tetraphosphatase
MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDLGEAAAS
>CP026473.1|AUY30735.1|3992341_3992719_+|Protein-ApaG
MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH
>CP026473.1|AUY30745.1|4002019_4003534_+|L-carnitine/gamma-butyrobetaine-antiporter
MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD
>CP026473.1|AUY30746.1|4003564_4004707_+|Crotonobetainyl-CoA-dehydrogenase
MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQVLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
>CP026473.1|AUY30747.1|4004835_4006053_+|L-carnitine-CoA-transferase
MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKARETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLSTPEIPEGTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED
>CP026473.1|AUY30748.1|4006126_4007680_+|putative-crotonobetaine/carnitine-CoA-ligase
MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELNQEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESAWILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQPATLCYAPPLLTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYLTVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPMMIRTLMVQPPSANDRQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRAGFCYEAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYCDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKIIRKNLK
>CP026473.1|AUY30749.1|4007788_4008574_+|Carnitinyl-CoA-dehydratase
MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDDPQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVMTGRRMGAEEALRWGIVNRVVNQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMPVEEAYRYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR
>CP026473.1|AUY30750.1|4008579_4009170_+|Carnitine-operon-protein-CaiE
MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCIMHGYCNTDTIVGENGHIGHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFIKAGFRGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQDLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR
>CP026473.1|AUY30751.1|4009288_4009684_-|Transcriptional-activatory-protein-CaiF
MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNTLTYILSEVTEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSREKLVGVRKTPRIPAVPLTELNREQKWQMMLSKSMRR
>CP026473.1|AUY30752.1|4009718_4009937_+|hypothetical-protein
MTRFEAIKQGHIKIVDISIVCNFTVDKCELNPAYVIKNIDSPKDLLNGQKKRSSSENRITYSIKLADEKYPP
>CP026473.1|AUY30753.1|4009944_4013166_-|Carbamoyl-phosphate-synthase-large-subunit
MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAADVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNAEFLRQLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAVERLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPAYTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKATGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIRRSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK
>CP026473.1|AUY30754.1|4013183_4014332_-|Carbamoyl-phosphate-synthase-small-chain
MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILTDPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYLKRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAKEVTTAEAYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTIVPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLALASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIEQYRKTAK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP026473_8	8.2\|3280862\|26\|CP026473\|PILER-CR	3280862-3280887	26	CP026473.1	2781073-2781098	0	1.0

1. spacer 8.2|3280862|26|CP026473|PILER-CR matches to position: 2781073-2781098, mismatch: 0, identity: 1.0

atttacctctttcaggtaaactttat	CRISPR spacer
atttacctctttcaggtaaactttat	Protospacer
**************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP026473_7	7.1\|2987378\|40\|CP026473\|CRISPRCasFinder	2987378-2987417	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	0	1.0
CP026473_8	8.1\|3280815\|25\|CP026473\|PILER-CR	3280815-3280839	25	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	44572-44596	0	1.0
CP026473_8	8.2\|3280862\|26\|CP026473\|PILER-CR	3280862-3280887	26	NC_049946	Escherichia virus Lambda_4A7 genome assembly, chromosome: 1	37604-37629	0	1.0
CP026473_8	8.2\|3280862\|26\|CP026473\|PILER-CR	3280862-3280887	26	LR595861	Escherichia virus Lambda_4C10 genome assembly, chromosome: 1	37887-37912	0	1.0
CP026473_11	11.1\|4001654\|42\|CP026473\|PILER-CR	4001654-4001695	42	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	141085-141126	0	1.0
CP026473_8	8.2\|3280862\|26\|CP026473\|PILER-CR	3280862-3280887	26	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	44524-44549	1	0.962
CP026473_11	11.2\|4001713\|40\|CP026473\|PILER-CR	4001713-4001752	40	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	141028-141067	1	0.975
CP026473_6	6.1\|2266251\|38\|CP026473\|CRISPRCasFinder	2266251-2266288	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
CP026473_8	8.1\|3280815\|25\|CP026473\|PILER-CR	3280815-3280839	25	NC_049946	Escherichia virus Lambda_4A7 genome assembly, chromosome: 1	37652-37676	2	0.92
CP026473_8	8.1\|3280815\|25\|CP026473\|PILER-CR	3280815-3280839	25	LR595861	Escherichia virus Lambda_4C10 genome assembly, chromosome: 1	37935-37959	2	0.92
CP026473_10	10.1\|3788244\|48\|CP026473\|CRISPRCasFinder	3788244-3788291	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4089-4136	3	0.938
CP026473_10	10.1\|3788244\|48\|CP026473\|CRISPRCasFinder	3788244-3788291	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4088-4135	3	0.938
CP026473_10	10.1\|3788244\|48\|CP026473\|CRISPRCasFinder	3788244-3788291	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4088-4135	3	0.938
CP026473_10	10.1\|3788244\|48\|CP026473\|CRISPRCasFinder	3788244-3788291	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4088-4135	3	0.938
CP026473_8	8.2\|3280862\|26\|CP026473\|PILER-CR	3280862-3280887	26	NZ_CP015341	Lactobacillus brevis strain 100D8 plasmid unnamed3, complete sequence	35661-35686	4	0.846
CP026473_1	1.1\|635763\|42\|CP026473\|CRISPRCasFinder	635763-635804	42	NZ_CP010208	Escherichia coli strain M11 plasmid B, complete sequence	30214-30255	7	0.833
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NZ_MG299151	Shigella sonnei strain SH287-2 plasmid pSH287-2, complete sequence	51276-51307	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NZ_KY471628	Shigella sonnei strain SH15sh99 plasmid pSH15sh99, complete sequence	45716-45747	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NZ_MG299131	Shigella sonnei strain SH271-2 plasmid pSH271-2, complete sequence	51276-51307	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NZ_KY471629	Shigella sonnei strain SH15sh105 plasmid pSH15sh104, complete sequence	45716-45747	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NZ_MG299133	Shigella sonnei strain SH272-2 plasmid pSH272-2, complete sequence	51276-51307	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NZ_MG299128	Shigella sonnei strain SH262-2 plasmid pSH262-2, complete sequence	51276-51307	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NZ_MG299147	Shigella sonnei strain SH284-2 plasmid pSH284-2, complete sequence	51276-51307	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NC_018995	Escherichia coli plasmid pHUSEC41-1, complete sequence	29015-29046	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NZ_CP053235	Escherichia coli strain SCU-106 plasmid pSCU-106-1, complete sequence	78292-78323	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NZ_CP005999	Escherichia coli B7A plasmid pEB1, complete sequence	39563-39594	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	KU932021	Escherichia coli plasmid pEC3I, complete sequence	51902-51933	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NZ_CP024154	Escherichia coli strain 14EC033 plasmid p14EC033g, complete sequence	18560-18591	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NC_011754	Escherichia coli ED1a plasmid pECOED, complete sequence	49240-49271	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NZ_CP015141	Escherichia coli strain Ecol_732 plasmid pEC732_3, complete sequence	81434-81465	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NZ_LR213460	Shigella sonnei strain AUSMDU00008333 isolate AUSMDU00008333 plasmid 3	28916-28947	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NZ_MH287044	Escherichia coli strain 5.1-R1 plasmid pCERC6, complete sequence	36182-36213	7	0.781
CP026473_3	3.7\|1051004\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1051004-1051035	32	NZ_MH618673	Escherichia coli strain 838B plasmid p838B-R, complete sequence	32230-32261	7	0.781
CP026473_4	4.1\|1073540\|31\|CP026473\|CRISPRCasFinder	1073540-1073570	31	NC_007336	Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence	62682-62712	7	0.774
CP026473_4	4.1\|1073540\|31\|CP026473\|CRISPRCasFinder	1073540-1073570	31	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	1222106-1222136	7	0.774
CP026473_4	4.1\|1073540\|31\|CP026473\|CRISPRCasFinder	1073540-1073570	31	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	2467672-2467702	7	0.774
CP026473_4	4.4\|1073723\|31\|CP026473\|CRISPRCasFinder	1073723-1073753	31	NZ_CP034185	Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence	17977-18007	7	0.774
CP026473_4	4.7\|1073906\|31\|CP026473\|CRISPRCasFinder	1073906-1073936	31	NC_007336	Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence	530641-530671	7	0.774
CP026473_1	1.1\|635763\|42\|CP026473\|CRISPRCasFinder	635763-635804	42	NZ_CP048307	Escherichia coli strain 9 plasmid p009_C, complete sequence	24899-24940	8	0.81
CP026473_3	3.6\|1050943\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1050943-1050974	32	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	1417960-1417991	8	0.75
CP026473_4	4.4\|1073723\|31\|CP026473\|CRISPRCasFinder	1073723-1073753	31	NZ_CP017753	Cupriavidus sp. USMAHM13 plasmid unnamed1, complete sequence	97498-97528	8	0.742
CP026473_4	4.7\|1073906\|31\|CP026473\|CRISPRCasFinder	1073906-1073936	31	NZ_CP036297	Planctomycetes bacterium Pla86 plasmid pPla86_1, complete sequence	14953-14983	8	0.742
CP026473_4	4.7\|1073906\|31\|CP026473\|CRISPRCasFinder	1073906-1073936	31	NZ_CP036288	Planctomycetes bacterium Pla133 plasmid pPla133_1, complete sequence	14983-15013	8	0.742
CP026473_4	4.7\|1073906\|31\|CP026473\|CRISPRCasFinder	1073906-1073936	31	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	3454-3484	8	0.742
CP026473_4	4.7\|1073906\|31\|CP026473\|CRISPRCasFinder	1073906-1073936	31	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	148992-149022	8	0.742
CP026473_4	4.10\|1073540\|32\|CP026473\|PILER-CR,CRT	1073540-1073571	32	NC_007336	Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence	62682-62713	8	0.75
CP026473_4	4.10\|1073540\|32\|CP026473\|PILER-CR,CRT	1073540-1073571	32	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	1222106-1222137	8	0.75
CP026473_4	4.10\|1073540\|32\|CP026473\|PILER-CR,CRT	1073540-1073571	32	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	2467671-2467702	8	0.75
CP026473_4	4.10\|1073540\|32\|CP026473\|PILER-CR,CRT	1073540-1073571	32	NC_008759	Polaromonas naphthalenivorans CJ2 plasmid pPNAP03, complete sequence	12670-12701	8	0.75
CP026473_4	4.13\|1073723\|32\|CP026473\|PILER-CR,CRT	1073723-1073754	32	NZ_CP034185	Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence	17977-18008	8	0.75
CP026473_4	4.13\|1073723\|32\|CP026473\|PILER-CR,CRT	1073723-1073754	32	NZ_CP017753	Cupriavidus sp. USMAHM13 plasmid unnamed1, complete sequence	97497-97528	8	0.75
CP026473_4	4.16\|1073906\|32\|CP026473\|PILER-CR,CRT	1073906-1073937	32	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	148991-149022	8	0.75
CP026473_4	4.16\|1073906\|32\|CP026473\|PILER-CR,CRT	1073906-1073937	32	NC_007336	Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence	530640-530671	8	0.75
CP026473_4	4.17\|1073967\|32\|CP026473\|PILER-CR,CRT	1073967-1073998	32	NZ_CP006991	Rhizobium sp. IE4771 plasmid pRetIE4771e, complete sequence	532343-532374	8	0.75
CP026473_1	1.1\|635763\|42\|CP026473\|CRISPRCasFinder	635763-635804	42	NZ_CP048307	Escherichia coli strain 9 plasmid p009_C, complete sequence	24786-24827	9	0.786
CP026473_4	4.1\|1073540\|31\|CP026473\|CRISPRCasFinder	1073540-1073570	31	NC_011987	Agrobacterium radiobacter K84 plasmid pAtK84c, complete sequence	86182-86212	9	0.71
CP026473_4	4.2\|1073601\|31\|CP026473\|CRISPRCasFinder	1073601-1073631	31	CP011075	Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence	244686-244716	9	0.71
CP026473_4	4.2\|1073601\|31\|CP026473\|CRISPRCasFinder	1073601-1073631	31	GU075905	Prochlorococcus phage P-HM2, complete genome	78536-78566	9	0.71
CP026473_4	4.4\|1073723\|31\|CP026473\|CRISPRCasFinder	1073723-1073753	31	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	405875-405905	9	0.71
CP026473_4	4.4\|1073723\|31\|CP026473\|CRISPRCasFinder	1073723-1073753	31	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2248363-2248393	9	0.71
CP026473_4	4.8\|1073967\|31\|CP026473\|CRISPRCasFinder	1073967-1073997	31	NZ_CP040723	Rhodococcus pyridinivorans strain YF3 plasmid unnamed4, complete sequence	35740-35770	9	0.71
CP026473_4	4.13\|1073723\|32\|CP026473\|PILER-CR,CRT	1073723-1073754	32	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	405875-405906	9	0.719
CP026473_4	4.16\|1073906\|32\|CP026473\|PILER-CR,CRT	1073906-1073937	32	NZ_CP036297	Planctomycetes bacterium Pla86 plasmid pPla86_1, complete sequence	14953-14984	9	0.719
CP026473_4	4.16\|1073906\|32\|CP026473\|PILER-CR,CRT	1073906-1073937	32	NZ_CP036288	Planctomycetes bacterium Pla133 plasmid pPla133_1, complete sequence	14983-15014	9	0.719
CP026473_4	4.16\|1073906\|32\|CP026473\|PILER-CR,CRT	1073906-1073937	32	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	3454-3485	9	0.719
CP026473_4	4.17\|1073967\|32\|CP026473\|PILER-CR,CRT	1073967-1073998	32	NZ_CP040723	Rhodococcus pyridinivorans strain YF3 plasmid unnamed4, complete sequence	35740-35771	9	0.719
CP026473_3	3.1\|1050638\|32\|CP026473\|PILER-CR,CRISPRCasFinder,CRT	1050638-1050669	32	NZ_CP030933	Enterococcus gilvus strain CR1 plasmid pCR1A, complete sequence	51062-51093	10	0.688
CP026473_4	4.10\|1073540\|32\|CP026473\|PILER-CR,CRT	1073540-1073571	32	NC_011987	Agrobacterium radiobacter K84 plasmid pAtK84c, complete sequence	86181-86212	10	0.688
CP026473_4	4.11\|1073601\|32\|CP026473\|PILER-CR,CRT	1073601-1073632	32	CP011075	Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence	244686-244717	10	0.688
CP026473_4	4.11\|1073601\|32\|CP026473\|PILER-CR,CRT	1073601-1073632	32	GU075905	Prochlorococcus phage P-HM2, complete genome	78536-78567	10	0.688
CP026473_4	4.13\|1073723\|32\|CP026473\|PILER-CR,CRT	1073723-1073754	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2248362-2248393	10	0.688

1. spacer 7.1|2987378|40|CP026473|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 0, identity: 1.0

gcgctgcgggtcattcttgaaattacccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
****************************************

2. spacer 8.1|3280815|25|CP026473|PILER-CR matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 0, identity: 1.0

gtgcctttacctgatttgggtaaac	CRISPR spacer
gtgcctttacctgatttgggtaaac	Protospacer
*************************

3. spacer 8.2|3280862|26|CP026473|PILER-CR matches to NC_049946 (Escherichia virus Lambda_4A7 genome assembly, chromosome: 1) position: , mismatch: 0, identity: 1.0

atttacctctttcaggtaaactttat	CRISPR spacer
atttacctctttcaggtaaactttat	Protospacer
**************************

4. spacer 8.2|3280862|26|CP026473|PILER-CR matches to LR595861 (Escherichia virus Lambda_4C10 genome assembly, chromosome: 1) position: , mismatch: 0, identity: 1.0

atttacctctttcaggtaaactttat	CRISPR spacer
atttacctctttcaggtaaactttat	Protospacer
**************************

5. spacer 11.1|4001654|42|CP026473|PILER-CR matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 0, identity: 1.0

tgtcacacgcagataaatccaactttcaatattgttaagttc	CRISPR spacer
tgtcacacgcagataaatccaactttcaatattgttaagttc	Protospacer
******************************************

6. spacer 8.2|3280862|26|CP026473|PILER-CR matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 1, identity: 0.962

atttacctctttcaggtaaactttat	CRISPR spacer
atttacctctttaaggtaaactttat	Protospacer
************ *************

7. spacer 11.2|4001713|40|CP026473|PILER-CR matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 1, identity: 0.975

catggcgtagcaaaaagaaattttcaatattgctttatgg	CRISPR spacer
catggcgtagaaaaaagaaattttcaatattgctttatgg	Protospacer
********** *****************************

8. spacer 6.1|2266251|38|CP026473|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cggacgcaggatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
*.*******.****************************

9. spacer 8.1|3280815|25|CP026473|PILER-CR matches to NC_049946 (Escherichia virus Lambda_4A7 genome assembly, chromosome: 1) position: , mismatch: 2, identity: 0.92

gtgcctttacctgatttgggtaaac	CRISPR spacer
acgcctttacctgatttgggtaaac	Protospacer
..***********************

10. spacer 8.1|3280815|25|CP026473|PILER-CR matches to LR595861 (Escherichia virus Lambda_4C10 genome assembly, chromosome: 1) position: , mismatch: 2, identity: 0.92

gtgcctttacctgatttgggtaaac	CRISPR spacer
acgcctttacctgatttgggtaaac	Protospacer
..***********************

11. spacer 10.1|3788244|48|CP026473|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 3, identity: 0.938

tcagcgtcgcatcaggcatctgcgcataaccgccggatgcggcgtaaa	CRISPR spacer
ccagcgtcgcatcaggcatctgcgcataactgccggatgcggcataaa	Protospacer
.*****************************.************.****

12. spacer 10.1|3788244|48|CP026473|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 3, identity: 0.938

tcagcgtcgcatcaggcatctgcgcataaccgccggatgcggcgtaaa	CRISPR spacer
ccagcgtcgcatcaggcatctgcgcataactgccggatgcggcataaa	Protospacer
.*****************************.************.****

13. spacer 10.1|3788244|48|CP026473|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 3, identity: 0.938

tcagcgtcgcatcaggcatctgcgcataaccgccggatgcggcgtaaa	CRISPR spacer
ccagcgtcgcatcaggcatctgcgcataactgccggatgcggcataaa	Protospacer
.*****************************.************.****

14. spacer 10.1|3788244|48|CP026473|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 3, identity: 0.938

tcagcgtcgcatcaggcatctgcgcataaccgccggatgcggcgtaaa	CRISPR spacer
ccagcgtcgcatcaggcatctgcgcataactgccggatgcggcataaa	Protospacer
.*****************************.************.****

15. spacer 8.2|3280862|26|CP026473|PILER-CR matches to NZ_CP015341 (Lactobacillus brevis strain 100D8 plasmid unnamed3, complete sequence) position: , mismatch: 4, identity: 0.846

atttacctctttcaggtaaactttat	CRISPR spacer
aggtatctcattcaggtaaactttat	Protospacer
*  **.*** ****************

16. spacer 1.1|635763|42|CP026473|CRISPRCasFinder matches to NZ_CP010208 (Escherichia coli strain M11 plasmid B, complete sequence) position: , mismatch: 7, identity: 0.833

acagcagtcggatgcggcgtaaacaccttatctgacctacgt	CRISPR spacer
acaaatgccggatgcggcgtaaacgccttatctggcctacgc	Protospacer
***.  *.****************.*********.******.

17. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MG299151 (Shigella sonnei strain SH287-2 plasmid pSH287-2, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

18. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY471628 (Shigella sonnei strain SH15sh99 plasmid pSH15sh99, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

19. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MG299131 (Shigella sonnei strain SH271-2 plasmid pSH271-2, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

20. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY471629 (Shigella sonnei strain SH15sh105 plasmid pSH15sh104, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

21. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MG299133 (Shigella sonnei strain SH272-2 plasmid pSH272-2, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

22. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MG299128 (Shigella sonnei strain SH262-2 plasmid pSH262-2, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

23. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MG299147 (Shigella sonnei strain SH284-2 plasmid pSH284-2, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

24. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NC_018995 (Escherichia coli plasmid pHUSEC41-1, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

25. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053235 (Escherichia coli strain SCU-106 plasmid pSCU-106-1, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

26. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP005999 (Escherichia coli B7A plasmid pEB1, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

27. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to KU932021 (Escherichia coli plasmid pEC3I, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

28. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024154 (Escherichia coli strain 14EC033 plasmid p14EC033g, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

29. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NC_011754 (Escherichia coli ED1a plasmid pECOED, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

30. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015141 (Escherichia coli strain Ecol_732 plasmid pEC732_3, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

31. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR213460 (Shigella sonnei strain AUSMDU00008333 isolate AUSMDU00008333 plasmid 3) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

32. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MH287044 (Escherichia coli strain 5.1-R1 plasmid pCERC6, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

33. spacer 3.7|1051004|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MH618673 (Escherichia coli strain 838B plasmid p838B-R, complete sequence) position: , mismatch: 7, identity: 0.781

aaatatccagggctgggctggaggcagacggc--	CRISPR spacer
cgttatccagggctgagctgcaggcag--ggcca	Protospacer
 . ************.**** ******  ***

34. spacer 4.1|1073540|31|CP026473|CRISPRCasFinder matches to NC_007336 (Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.774

ttgcccgcgcaattccgggagcatccgcaat	CRISPR spacer
tccctatcgcaatgccggcagcatccgcaat	Protospacer
*. *.  ****** **** ************

35. spacer 4.1|1073540|31|CP026473|CRISPRCasFinder matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.774

ttgcccgcgcaattccgggagcatccgcaat	CRISPR spacer
ttgcgcgcgcaattccgtgagcagcgccatc	Protospacer
**** ************ ***** *  ** .

36. spacer 4.1|1073540|31|CP026473|CRISPRCasFinder matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

ttgcccgcgcaattccgggagcatccgcaat	CRISPR spacer
ttgcgcgcgcaattccgtgagcagcgccatc	Protospacer
**** ************ ***** *  ** .

37. spacer 4.4|1073723|31|CP026473|CRISPRCasFinder matches to NZ_CP034185 (Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

cccgtcaccgacgcgcagtggcgctaccgtg	CRISPR spacer
agcgtcaccgacgcgcagggccgctaccaac	Protospacer
  **************** * *******.

38. spacer 4.7|1073906|31|CP026473|CRISPRCasFinder matches to NC_007336 (Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.774

ccgaacggctggcgaagcaggtggctggcgt	CRISPR spacer
ccgaacaggtggcgaagcaggtgatgggcca	Protospacer
******.* **************.. ***

39. spacer 1.1|635763|42|CP026473|CRISPRCasFinder matches to NZ_CP048307 (Escherichia coli strain 9 plasmid p009_C, complete sequence) position: , mismatch: 8, identity: 0.81

acagcagtcggatgcggcgtaaacaccttatctgacctacgt	CRISPR spacer
attgatgtcggatgcggcgtaaacgccttatccgacctacaa	Protospacer
*. *  ******************.*******.*******.

40. spacer 3.6|1050943|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

tcaacgcgctcagacgttgcgtgagtgaacca	CRISPR spacer
acaacgcggtcggacgttgcgtgattaccccg	Protospacer
 ******* **.************ *.  **.

41. spacer 4.4|1073723|31|CP026473|CRISPRCasFinder matches to NZ_CP017753 (Cupriavidus sp. USMAHM13 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

cccgtcaccgacgcgcagtggcgctaccgtg	CRISPR spacer
gacgtcaccgacgcgcagtcgcgcttcttca	Protospacer
  ***************** ***** *. ..

42. spacer 4.7|1073906|31|CP026473|CRISPRCasFinder matches to NZ_CP036297 (Planctomycetes bacterium Pla86 plasmid pPla86_1, complete sequence) position: , mismatch: 8, identity: 0.742

ccgaacggctggcgaagcaggtggctggcgt	CRISPR spacer
agcggcagctggcgatgcaggtggcttgcgt	Protospacer
   ..*.******** ********** ****

43. spacer 4.7|1073906|31|CP026473|CRISPRCasFinder matches to NZ_CP036288 (Planctomycetes bacterium Pla133 plasmid pPla133_1, complete sequence) position: , mismatch: 8, identity: 0.742

ccgaacggctggcgaagcaggtggctggcgt	CRISPR spacer
agcggcagctggcgatgcaggtggcttgcgt	Protospacer
   ..*.******** ********** ****

44. spacer 4.7|1073906|31|CP026473|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 8, identity: 0.742

ccgaacggctggcgaagcaggtggctggcgt	CRISPR spacer
ttgcgcagctggcgcagcaggtggctgccga	Protospacer
..* .*.******* ************ **

45. spacer 4.7|1073906|31|CP026473|CRISPRCasFinder matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

ccgaacggctggcgaagcaggtggctggcgt	CRISPR spacer
gggtacggctggcgaaggaggcggctgcgga	Protospacer
  * ************* ***.*****  *

46. spacer 4.10|1073540|32|CP026473|PILER-CR,CRT matches to NC_007336 (Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.75

ttgcccgcgcaattccgggagcatccgcaatt	CRISPR spacer
tccctatcgcaatgccggcagcatccgcaatc	Protospacer
*. *.  ****** **** ************.

47. spacer 4.10|1073540|32|CP026473|PILER-CR,CRT matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.75

ttgcccgcgcaattccgggagcatccgcaatt	CRISPR spacer
ttgcgcgcgcaattccgtgagcagcgccatca	Protospacer
**** ************ ***** *  ** .

48. spacer 4.10|1073540|32|CP026473|PILER-CR,CRT matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

ttgcccgcgcaattccgggagcatccgcaatt	CRISPR spacer
ttgcgcgcgcaattccgtgagcagcgccatca	Protospacer
**** ************ ***** *  ** .

49. spacer 4.10|1073540|32|CP026473|PILER-CR,CRT matches to NC_008759 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP03, complete sequence) position: , mismatch: 8, identity: 0.75

ttgcccgcg-----caattccgggagcatccgcaatt	CRISPR spacer
-----cgtgaaactcatttccgggagcatccgcattt	Protospacer
     **.*     ** ***************** **

50. spacer 4.13|1073723|32|CP026473|PILER-CR,CRT matches to NZ_CP034185 (Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

cccgtcaccgacgcgcagtggcgctaccgtga	CRISPR spacer
agcgtcaccgacgcgcagggccgctaccaact	Protospacer
  **************** * *******.

51. spacer 4.13|1073723|32|CP026473|PILER-CR,CRT matches to NZ_CP017753 (Cupriavidus sp. USMAHM13 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

cccgtcaccgacgcgcagtggcgctaccgtga	CRISPR spacer
gacgtcaccgacgcgcagtcgcgcttcttcaa	Protospacer
  ***************** ***** *. ..*

52. spacer 4.16|1073906|32|CP026473|PILER-CR,CRT matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ccgaacggctggcgaagcaggtggctggcgta	CRISPR spacer
gggtacggctggcgaaggaggcggctgcggaa	Protospacer
  * ************* ***.*****  * *

53. spacer 4.16|1073906|32|CP026473|PILER-CR,CRT matches to NC_007336 (Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.75

ccgaacggctggcgaagcaggtggctggcgta	CRISPR spacer
ccgaacaggtggcgaagcaggtgatgggccag	Protospacer
******.* **************.. ***  .

54. spacer 4.17|1073967|32|CP026473|PILER-CR,CRT matches to NZ_CP006991 (Rhizobium sp. IE4771 plasmid pRetIE4771e, complete sequence) position: , mismatch: 8, identity: 0.75

gtttaccgccccgcagaggcgctggcagatcc	CRISPR spacer
catcatcctcccgcagatgcgctggccgatcc	Protospacer
  *.*.* .******** ******** *****

55. spacer 1.1|635763|42|CP026473|CRISPRCasFinder matches to NZ_CP048307 (Escherichia coli strain 9 plasmid p009_C, complete sequence) position: , mismatch: 9, identity: 0.786

acagcagtcggatgcggcgtaaacaccttatctgacctacgt	CRISPR spacer
gttgatgtcggatgcggcgtaaacgccttatccgacctacaa	Protospacer
.. *  ******************.*******.*******.

56. spacer 4.1|1073540|31|CP026473|CRISPRCasFinder matches to NC_011987 (Agrobacterium radiobacter K84 plasmid pAtK84c, complete sequence) position: , mismatch: 9, identity: 0.71

ttgcccgcgcaattccgggagcatccgcaat	CRISPR spacer
gctaccgcgcaattcgaggagcatccgctgg	Protospacer
 .  *********** .*********** .

57. spacer 4.2|1073601|31|CP026473|CRISPRCasFinder matches to CP011075 (Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

acggacaaaatatatattgatttgcgaatta	CRISPR spacer
tgaggcaaaatatagattgatttccgaaaat	Protospacer
  .*.********* ******** ****

58. spacer 4.2|1073601|31|CP026473|CRISPRCasFinder matches to GU075905 (Prochlorococcus phage P-HM2, complete genome) position: , mismatch: 9, identity: 0.71

acggacaaaatatatattgatttgcgaatta	CRISPR spacer
acggaaaaattatatattgattttacttctg	Protospacer
***** *** *************     .*.

59. spacer 4.4|1073723|31|CP026473|CRISPRCasFinder matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

cccgtcaccgacgcgcagtggcgctaccgtg	CRISPR spacer
gacgtcactgacgcgcagtcgcgcttcttca	Protospacer
  ******.********** ***** *. ..

60. spacer 4.4|1073723|31|CP026473|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.71

cccgtcaccgacgcgcagtggcgctaccgtg	CRISPR spacer
gacatcaccgacgcccagtggcgcgacgtcc	Protospacer
  *.********** ********* **  .

61. spacer 4.8|1073967|31|CP026473|CRISPRCasFinder matches to NZ_CP040723 (Rhodococcus pyridinivorans strain YF3 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.71

gtttaccgccccgcagaggcgctggcagatc	CRISPR spacer
cgagaccgcctcgccgaggcgctggcagcga	Protospacer
    ******.*** *************

62. spacer 4.13|1073723|32|CP026473|PILER-CR,CRT matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cccgtcaccgacgcgcagtggcgctaccgtga	CRISPR spacer
gacgtcactgacgcgcagtcgcgcttcttcaa	Protospacer
  ******.********** ***** *. ..*

63. spacer 4.16|1073906|32|CP026473|PILER-CR,CRT matches to NZ_CP036297 (Planctomycetes bacterium Pla86 plasmid pPla86_1, complete sequence) position: , mismatch: 9, identity: 0.719

ccgaacggctggcgaagcaggtggctggcgta	CRISPR spacer
agcggcagctggcgatgcaggtggcttgcgtg	Protospacer
   ..*.******** ********** ****.

64. spacer 4.16|1073906|32|CP026473|PILER-CR,CRT matches to NZ_CP036288 (Planctomycetes bacterium Pla133 plasmid pPla133_1, complete sequence) position: , mismatch: 9, identity: 0.719

ccgaacggctggcgaagcaggtggctggcgta	CRISPR spacer
agcggcagctggcgatgcaggtggcttgcgtg	Protospacer
   ..*.******** ********** ****.

65. spacer 4.16|1073906|32|CP026473|PILER-CR,CRT matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 9, identity: 0.719

ccgaacggctggcgaagcaggtggctggcgta	CRISPR spacer
ttgcgcagctggcgcagcaggtggctgccgag	Protospacer
..* .*.******* ************ ** .

66. spacer 4.17|1073967|32|CP026473|PILER-CR,CRT matches to NZ_CP040723 (Rhodococcus pyridinivorans strain YF3 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.719

gtttaccgccccgcagaggcgctggcagatcc	CRISPR spacer
cgagaccgcctcgccgaggcgctggcagcgac	Protospacer
    ******.*** *************   *

67. spacer 3.1|1050638|32|CP026473|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030933 (Enterococcus gilvus strain CR1 plasmid pCR1A, complete sequence) position: , mismatch: 10, identity: 0.688

tccacgctgtaacggccatcattaagtttagt	CRISPR spacer
ccgctgctgtgacgcccatcattaagttactc	Protospacer
.*  .*****.*** *************   .

68. spacer 4.10|1073540|32|CP026473|PILER-CR,CRT matches to NC_011987 (Agrobacterium radiobacter K84 plasmid pAtK84c, complete sequence) position: , mismatch: 10, identity: 0.688

ttgcccgcgcaattccgggagcatccgcaatt	CRISPR spacer
gctaccgcgcaattcgaggagcatccgctggg	Protospacer
 .  *********** .*********** .

69. spacer 4.11|1073601|32|CP026473|PILER-CR,CRT matches to CP011075 (Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

acggacaaaatatatattgatttgcgaattat	CRISPR spacer
tgaggcaaaatatagattgatttccgaaaata	Protospacer
  .*.********* ******** ****

70. spacer 4.11|1073601|32|CP026473|PILER-CR,CRT matches to GU075905 (Prochlorococcus phage P-HM2, complete genome) position: , mismatch: 10, identity: 0.688

acggacaaaatatatattgatttgcgaattat	CRISPR spacer
acggaaaaattatatattgattttacttctgg	Protospacer
***** *** *************     .*.

71. spacer 4.13|1073723|32|CP026473|PILER-CR,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 10, identity: 0.688

cccgtcaccgacgcgcagtggcgctaccgtga	CRISPR spacer
gacatcaccgacgcccagtggcgcgacgtccc	Protospacer
  *.********** ********* **  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1707570 : 1717012

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUY28730.1\|1707570_1708497_+	osmoprotectant transport system ATP-binding protein	G3M9Y6	Bacillus_virus	1.7e-23	30.8
AUY28731.1\|1708501_1709233_+	osmoprotectant transport system permease protein	NA	NA	NA	NA
AUY28732.1\|1709380_1710112_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	9.7e-112	99.5
AUY28733.1\|1710333_1712019_+	Histidine kinase	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
AUY28734.1\|1712015_1712735_+	Transcriptional regulatory protein YehT	NA	NA	NA	NA
AUY28735.1\|1712781_1713252_+	hypothetical protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
AUY28736.1\|1713292_1713754_-	hypothetical protein	Q9EYF5	Enterobacteria_phage	1.9e-76	100.0
AUY28737.1\|1713878_1715879_-	SWIM zinc finger family protein	Q9EYF6	Enterobacteria_phage	0.0e+00	96.3
AUY28738.1\|1715875_1717012_-	hypothetical protein	Q9EYF7	Enterobacteria_phage	3.2e-162	97.4

DBSCAN-SWA_2

1817369 : 1825889

Acanthocystis_turfacea_Chlorella_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUY28821.1\|1817369_1818488_+	GDP-mannose 4,6-dehydratase	M1HVG7	Acanthocystis_turfacea_Chlorella_virus	8.7e-136	65.5
AUY28822.1\|1818491_1819457_+	GDP-L-fucose synthase	M1HWW2	Paramecium_bursaria_Chlorella_virus	4.9e-87	50.8
AUY28823.1\|1819459_1819921_+	GDP-mannose mannosyl hydrolase	NA	NA	NA	NA
AUY28824.1\|1819926_1821333_+	bifunctional Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	1.6e-49	29.5
AUY28825.1\|1821332_1822079_+	glycosyl transferase	A0A1V0SAH6	Catovirus	1.6e-08	39.3
AUY28826.1\|1822084_1823509_+	phosphomannomutase	NA	NA	NA	NA
AUY28827.1\|1823606_1823882_+	Insertion element IS1 protein	Q71TE9	Escherichia_phage	3.1e-47	100.0
AUY28828.1\|1824482_1825889_+	6-phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	1.4e-37	28.3

DBSCAN-SWA_3

1843455 : 1852769

Enterobacteria_phage(76.92%)

integrase,transposase,terminase

attL 1841635:1841648|attR 1851256:1851269

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1841635:1841648	attL	NA	NA	NA	NA
AUY28847.1\|1843455_1844352_+\|integrase	Phage integrase family protein	A0A0P0ZDN8	Stx2-converting_phage	1.9e-173	99.7
AUY28848.1\|1844332_1844524_-	AlpA family transcriptional regulator	A0A0P0ZBL0	Stx2-converting_phage	1.7e-31	100.0
AUY28849.1\|1844628_1844808_-	Eag protein	K7PL40	Enterobacteria_phage	7.3e-29	98.3
AUY28850.1\|1844820_1845402_+	Serine/threonine-protein phosphatase	K7P721	Enterobacteria_phage	7.7e-112	99.0
AUY28851.1\|1845398_1846022_+	Antitermination Q	K7PM87	Enterobacteria_phage	2.0e-113	99.0
AUY28852.1\|1846455_1846779_+	Holin	G5DA93	Enterobacteria_phage	1.3e-52	100.0
AUY28853.1\|1846762_1847239_+	Lysozyme	K7PKV2	Enterobacteria_phage	1.7e-88	100.0
AUY28854.1\|1847235_1847673_+	Phage endopeptidase	K7P710	Enterobacteria_phage	1.4e-68	95.9
AUY28855.1\|1847709_1847985_+	hypothetical protein	K7P6G5	Enterobacteria_phage	2.7e-46	100.0
AUY28856.1\|1848268_1848637_+	hypothetical protein	K7PH35	Enterobacteria_phage	1.5e-60	97.6
AUY28857.1\|1848740_1848983_+	hypothetical protein	A5VW77	Enterobacteria_phage	1.3e-36	100.0
AUY28858.1\|1848985_1849426_+\|terminase	Phage terminase small subunit	C7U0V7	Enterobacteria_phage	1.7e-79	99.3
AUY28859.1\|1851746_1852769_+\|transposase	transposase	A0A2L1IVA1	Escherichia_phage	1.0e-199	99.1
1851256:1851269	attR	NA	NA	NA	NA

DBSCAN-SWA_4

2352051 : 2366154

Escherichia_phage(22.22%)

integrase

attL 2349755:2349768|attR 2362120:2362133

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2349755:2349768	attL	NA	NA	NA	NA
AUY29303.1\|2352051_2354478_-	Anaerobic dimethyl sulfoxide reductase chain A	A0A077SK27	Escherichia_phage	7.7e-214	49.0
AUY29304.1\|2354676_2354982_-	hypothetical protein	NA	NA	NA	NA
AUY29305.1\|2355053_2355800_+	lipoprotein	NA	NA	NA	NA
AUY29306.1\|2355802_2356363_-	diamine N-acetyltransferase	NA	NA	NA	NA
AUY29307.1\|2356397_2356739_-	hypothetical protein	NA	NA	NA	NA
AUY29308.1\|2356873_2357200_+	hypothetical protein	A0A218MNG8	uncultured_virus	9.9e-24	55.6
AUY29309.1\|2357405_2358620_+	mannonate dehydratase	Q6A202	Oenococcus_phage	1.4e-46	29.0
AUY29310.1\|2358631_2359651_+	mannonate dehydratase	E3SJ82	Synechococcus_phage	4.3e-17	26.2
AUY29311.1\|2359838_2361119_-\|integrase	Phage integrase family protein	B6DZ48	Enterobacteria_phage	6.6e-156	62.3
AUY29312.1\|2361153_2361390_-	DNA-binding protein	S4TND0	Salmonella_phage	6.1e-15	50.7
AUY29313.1\|2361477_2363949_-	Exonuclease VIII	K7PLW7	Enterobacteria_phage	6.1e-57	59.8
2362120:2362133	attR	NA	NA	NA	NA
AUY29314.1\|2364042_2364234_-	hypothetical protein	NA	NA	NA	NA
AUY29315.1\|2364725_2365691_+	hypothetical protein	U5P0A0	Shigella_phage	9.7e-59	63.9
AUY29316.1\|2365731_2366154_+	hypothetical protein	A0A0U2QQN3	Escherichia_phage	2.0e-61	85.6

DBSCAN-SWA_5

2777237 : 2788015

Enterobacteria_phage(36.36%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUY29681.1\|2777237_2779193_-	5-methylcytosine-specific restriction enzyme B	K4I1H4	Acidithiobacillus_phage	7.5e-26	28.6
AUY29682.1\|2780982_2781471_-	Phage replication protein O family protein	A0A0M5M7Y1	Salmonella_phage	2.6e-36	50.0
AUY29683.1\|2781557_2782097_-	hypothetical protein	M9NZI6	Enterobacteria_phage	7.5e-61	65.6
AUY29684.1\|2782285_2782591_+	hypothetical protein	A0A0N7KZJ3	Stx2-converting_phage	2.3e-43	100.0
AUY29685.1\|2782587_2783268_+	Exonuclease	A0A0P0ZCD4	Stx2-converting_phage	5.1e-131	98.7
AUY29686.1\|2783264_2783423_+	hypothetical protein	M1FJ61	Enterobacteria_phage	6.4e-21	88.5
AUY29687.1\|2783419_2784484_+	DGQHR domain protein	T1SBJ4	Salmonella_phage	1.7e-133	64.8
AUY29688.1\|2784637_2784856_+	hypothetical protein	M1FQT7	Enterobacteria_phage	3.2e-34	94.4
AUY29689.1\|2784903_2785143_+	hypothetical protein	M1FPC8	Enterobacteria_phage	3.9e-38	94.9
AUY29690.1\|2785282_2785519_+	Excisionase	NA	NA	NA	NA
AUY29691.1\|2785508_2786651_+	Integrase	O21929	Phage_21	8.1e-206	99.7
AUY29692.1\|2786764_2788015_-	isocitrate dehydrogenase	Q77Z09	Phage_21	3.8e-23	100.0

DBSCAN-SWA_6

3175154 : 3183924

Salmonella_phage(88.89%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUY30025.1\|3175154_3175520_-	hypothetical protein	A0A1S6L006	Salmonella_phage	2.9e-24	95.2
AUY30026.1\|3175501_3177895_-	Bacteriophage replication A family protein	E5G6L9	Salmonella_phage	0.0e+00	93.7
AUY30027.1\|3177891_3178749_-	DNA adenine methylase	E5G6L8	Salmonella_phage	9.5e-159	95.8
AUY30028.1\|3178745_3178973_-	hypothetical protein	E5G6L7	Salmonella_phage	7.8e-36	98.7
AUY30029.1\|3178972_3179206_-	hypothetical protein	E5G6L6	Salmonella_phage	1.9e-32	97.4
AUY30030.1\|3179273_3179615_-	hypothetical protein	E5G6L5	Salmonella_phage	1.7e-55	98.2
AUY30031.1\|3179637_3179862_-	hypothetical protein	NA	NA	NA	NA
AUY30032.1\|3180036_3180546_-	Phage regulatory protein CII	E5G6L3	Salmonella_phage	1.3e-86	98.2
AUY30033.1\|3180578_3180800_-	Putative phage regulatory protein	NA	NA	NA	NA
AUY30034.1\|3180888_3181824_+	Bacteriophage CI repressor helix-turn-helix domain protein	A0A1S6KZZ7	Salmonella_phage	1.8e-30	39.4
AUY30035.1\|3181835_3182780_+	hypothetical protein	NA	NA	NA	NA
AUY30036.1\|3182871_3183924_+	Phage intergrase	A0A218M4I3	Erwinia_phage	1.4e-106	57.0

DBSCAN-SWA_7

3266076 : 3289404

Enterobacteria_phage(50.0%)

lysis

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUY30111.1\|3266076_3267408_+	Diguanylate cyclase domain protein	A0A127AWB9	Bacillus_phage	1.4e-20	37.1
AUY30112.1\|3267819_3268476_+	Methyltransferase domain protein	NA	NA	NA	NA
AUY30113.1\|3269366_3269927_-	Terminase small subunit	A0A0K2FIG2	Enterobacteria_phage	4.9e-87	98.8
AUY30114.1\|3270605_3271016_+	hypothetical protein	C6ZCX4	Enterobacteria_phage	1.3e-52	76.3
AUY30115.1\|3271061_3271226_+	hypothetical protein	NA	NA	NA	NA
AUY30116.1\|3271367_3271520_-	hypothetical protein	K7PKL2	Enterobacteria_phage	3.1e-20	96.0
AUY30117.1\|3271507_3271987_-	prophage endopeptidase	A0A2D1GLQ7	Escherichia_phage	1.6e-75	96.8
AUY30118.1\|3271971_3272469_-	Lysozyme	A0A1B5FP97	Escherichia_phage	1.6e-89	97.0
AUY30119.1\|3272468_3272684_-\|lysis	Phage lysis protein	A5LH82	Enterobacteria_phage	1.2e-33	98.6
AUY30120.1\|3272871_3273459_-	hypothetical protein	NA	NA	NA	NA
AUY30121.1\|3273467_3273602_-	araC-type regulatory protein	NA	NA	NA	NA
AUY30122.1\|3273755_3273917_-	hypothetical protein	NA	NA	NA	NA
AUY30123.1\|3273953_3274913_-	hypothetical protein	NA	NA	NA	NA
AUY30124.1\|3275105_3275630_+	apolipoprotein D and lipocalin family protein	A0A1W6JNX6	Morganella_phage	1.1e-48	54.1
AUY30125.1\|3275785_3276163_-	Antitermination protein Q-like protein	Q777W5	Enterobacteria_phage	7.3e-55	84.2
AUY30126.1\|3276248_3276386_-	Phage protein	K7PHH3	Enterobacteria_phage	9.2e-08	68.3
AUY30127.1\|3276385_3276748_-	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	1.5e-60	97.4
AUY30128.1\|3276744_3277035_-	hypothetical protein	K7PGZ6	Enterobacteria_phage	4.8e-46	91.7
AUY30129.1\|3277027_3277198_-	hypothetical protein	K7P7K0	Enterobacteria_phage	2.4e-13	69.8
AUY30130.1\|3277197_3277653_-	Putative DNA base-flipping protein	I6PD71	Cronobacter_phage	5.9e-59	66.2
AUY30131.1\|3277843_3278296_-	hypothetical protein	NA	NA	NA	NA
AUY30132.1\|3278292_3278853_-	hypothetical protein	NA	NA	NA	NA
AUY30133.1\|3279109_3279301_+	hypothetical protein	NA	NA	NA	NA
AUY30134.1\|3279337_3279631_-	Protein ren	A0A0N6WES4	Escherichia_phage	1.1e-42	95.7
AUY30135.1\|3279627_3280329_-	Replication P family protein	K7P6G2	Enterobacteria_phage	3.8e-129	99.6
AUY30136.1\|3280325_3281330_-	Phage replication protein O domain	A0A0M5M7Y1	Salmonella_phage	1.6e-109	63.4
AUY30137.1\|3281341_3281881_-	hypothetical protein	M9NZI6	Enterobacteria_phage	2.0e-61	66.1
AUY30138.1\|3281950_3282181_-	Antirepressor	A0A2H4FNF3	Salmonella_phage	1.5e-21	68.0
AUY30139.1\|3282219_3282975_+	hypothetical protein	Q76H56	Enterobacteria_phage	1.4e-92	75.0
AUY30140.1\|3283097_3283847_+	hypothetical protein	NA	NA	NA	NA
AUY30141.1\|3283843_3284671_+	hypothetical protein	NA	NA	NA	NA
AUY30142.1\|3285179_3285386_+	hypothetical protein	K7P6H3	Enterobacteria_phage	3.2e-28	85.3
AUY30143.1\|3285461_3285758_+	Host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	1.6e-49	100.0
AUY30144.1\|3285763_3286549_+	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
AUY30145.1\|3286545_3287226_+	Exonuclease	A0A0P0ZCD4	Stx2-converting_phage	3.0e-131	98.7
AUY30146.1\|3287222_3287405_+	hypothetical protein	A0A0N7CHV0	Escherichia_phage	2.2e-28	98.3
AUY30147.1\|3287377_3287569_+	hypothetical protein	A0A0P0ZC67	Stx2-converting_phage	2.8e-26	98.4
AUY30148.1\|3287645_3287861_+	hypothetical protein	A0A1I9LJM7	Stx_converting_phage	1.0e-32	100.0
AUY30149.1\|3288391_3288541_-	hypothetical protein	NA	NA	NA	NA
AUY30150.1\|3289236_3289404_+	hypothetical protein	A5VWB7	Enterobacteria_phage	2.9e-27	98.2

DBSCAN-SWA_8

4534062 : 4618632

Escherichia_virus(20.0%)

tRNA,protease,tail,lysis

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUY31198.1\|4534062_4535163_+\|tRNA	tRNA/tmRNA (uracil-C(5))-methyltransferase	NA	NA	NA	NA
AUY31199.1\|4535202_4535562_-	hypothetical protein	NA	NA	NA	NA
AUY31200.1\|4535561_4536266_-	DNA-binding transcriptional regulator	NA	NA	NA	NA
AUY31201.1\|4536542_4537943_+	Soluble pyridine nucleotide transhydrogenase	NA	NA	NA	NA
AUY31202.1\|4537925_4538843_-	R family transcriptional regulator	NA	NA	NA	NA
AUY31203.1\|4539094_4540378_-	MFS transporter	NA	NA	NA	NA
AUY31204.1\|4540444_4541659_-	mannonate dehydratase	Q6A202	Oenococcus_phage	5.9e-45	28.6
AUY31205.1\|4542155_4543529_-	Argininosuccinate lyase	NA	NA	NA	NA
AUY31206.1\|4543589_4544366_-	Acetylglutamate kinase	NA	NA	NA	NA
AUY31207.1\|4544373_4545378_-	N-acetyl-gamma-glutamyl-phosphate reductase	NA	NA	NA	NA
AUY31208.1\|4545531_4546683_+	Acetylornithine deacetylase	NA	NA	NA	NA
AUY31209.1\|4547034_4549686_+	Phosphoenolpyruvate carboxylase	NA	NA	NA	NA
AUY31210.1\|4549868_4551602_+	Phosphoethanolamine transferase CptA	NA	NA	NA	NA
AUY31211.1\|4551750_4552602_+	HTH-type transcriptional regulator	NA	NA	NA	NA
AUY31212.1\|4552588_4552930_-	PTS system, fructose-specific IIB-like component	NA	NA	NA	NA
AUY31213.1\|4552931_4553810_-	pyruvate formate lyase activating enzyme	NA	NA	NA	NA
AUY31214.1\|4553775_4556073_-	formate C-acetyltransferase	A0A1S6UAD4	Serratia_phage	4.6e-06	48.1
AUY31215.1\|4556123_4556444_-	PTS system, fructose-specific IIB-like component	NA	NA	NA	NA
AUY31216.1\|4556458_4557538_-	PTS system fructose-like transporter subunit EIIC	NA	NA	NA	NA
AUY31217.1\|4557846_4560348_+	PTS fructose transporter subunit IIA	A0A1V0SGR7	Hokovirus	1.0e-11	26.9
AUY31218.1\|4560359_4561022_+	Fructose-6-phosphate aldolase	A0A0E3F0E2	Synechococcus_phage	5.5e-29	34.6
AUY31219.1\|4561032_4562136_+	Glycerol dehydrogenase	NA	NA	NA	NA
AUY31220.1\|4562410_4563028_+	Putative amidase domain protein	NA	NA	NA	NA
AUY31221.1\|4563054_4563960_-	hypothetical protein	NA	NA	NA	NA
AUY31222.1\|4564053_4566234_-	Catalase-peroxidase	NA	NA	NA	NA
AUY31223.1\|4566562_4567453_-	5,10-methylenetetrahydrofolate reductase	NA	NA	NA	NA
AUY31224.1\|4567801_4570234_-	Bifunctional aspartokinase/homoserine dehydrogenase 2	NA	NA	NA	NA
AUY31225.1\|4570236_4571397_-	Cystathionine gamma-synthase	NA	NA	NA	NA
AUY31226.1\|4572174_4572783_+	hypothetical protein	NA	NA	NA	NA
AUY31227.1\|4572927_4573200_+	Insertion element iso-IS1N protein insA	A0A0U2RK18	Escherichia_phage	1.8e-34	81.0
AUY31228.1\|4573770_4574064_-	Insertion element IS1 8 protein insB	U5P0U6	Shigella_phage	7.2e-42	87.9
AUY31229.1\|4574789_4578962_-	Protein rhsC	A0A2H4JFP5	uncultured_Caudovirales_phage	4.7e-25	32.5
AUY31230.1\|4579121_4579334_-	50S ribosomal protein L31	NA	NA	NA	NA
AUY31231.1\|4579536_4581735_+	Primosome assembly protein PriA	NA	NA	NA	NA
AUY31232.1\|4581890_4582916_+	HTH-type transcriptional repressor CytR	NA	NA	NA	NA
AUY31233.1\|4584059_4584590_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
AUY31234.1\|4584599_4585931_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A191ZC11	Erwinia_phage	1.7e-45	29.9
AUY31235.1\|4585997_4586924_+	1,4-dihydroxy-2-naphthoate octaprenyltransferase	NA	NA	NA	NA
AUY31236.1\|4587016_4587502_+	Regulator of ribonuclease activity A	NA	NA	NA	NA
AUY31237.1\|4587586_4587826_-	Cell division protein ZapB	NA	NA	NA	NA
AUY31238.1\|4588257_4589103_+	Glycerol uptake facilitator protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	4.4e-15	28.0
AUY31239.1\|4589125_4590634_+	Glycerol kinase	NA	NA	NA	NA
AUY31240.1\|4590637_4591777_+	Fructose-1,6-bisphosphatase	NA	NA	NA	NA
AUY31241.1\|4591873_4592620_+	Ferredoxin--NADP reductase	NA	NA	NA	NA
AUY31242.1\|4592624_4593053_-	Universal stress protein D	NA	NA	NA	NA
AUY31243.1\|4593079_4593379_-	hypothetical protein	NA	NA	NA	NA
AUY31244.1\|4593590_4594031_-	hypothetical protein	NA	NA	NA	NA
AUY31245.1\|4594131_4594731_+	hypothetical protein	NA	NA	NA	NA
AUY31246.1\|4594838_4595606_+	Triosephosphate isomerase	NA	NA	NA	NA
AUY31247.1\|4595660_4596416_-	CDP-diacylglycerol pyrophosphatase	NA	NA	NA	NA
AUY31248.1\|4596522_4597512_-	Periplasmic sulfate-binding protein	NA	NA	NA	NA
AUY31249.1\|4597831_4598794_-	ATP-dependent 6-phosphofructokinase isozyme 1	NA	NA	NA	NA
AUY31250.1\|4598974_4599877_-	Ferrous-iron efflux pump FieF	NA	NA	NA	NA
AUY31251.1\|4601579_4602479_-	hypothetical protein	Q7Y4D2	Escherichia_virus	4.0e-168	99.7
AUY31252.1\|4602694_4603222_-	Tail fiber assembly protein GpG	A0A0C4UR05	Shigella_phage	5.1e-86	88.6
AUY31253.1\|4603223_4604225_-\|tail	Phage tail fiber protein	A0A0C4UQV0	Shigella_phage	1.2e-176	91.7
AUY31254.1\|4604748_4605534_+	Putative phage protein	NA	NA	NA	NA
AUY31255.1\|4605605_4606058_-\|tail	Putative tail protein	A0A0F7LBV9	Escherichia_phage	5.3e-76	98.7
AUY31256.1\|4606050_4606518_-\|tail	Phage tail completion protein GpR	Q7Y4E0	Escherichia_virus	1.9e-81	98.7
AUY31257.1\|4606480_4606639_-\|lysis	Phage lysis protein LysC	M1RZ27	Escherichia_phage	2.6e-22	100.0
AUY31258.1\|4606625_4607051_-\|lysis	Phage lysis timing protein LysB	Q858W0	Yersinia_virus	5.5e-67	98.6
AUY31259.1\|4607038_4607440_-\|lysis	Phage lysis protein LysA	Q858W1	Yersinia_virus	5.1e-54	90.2
AUY31260.1\|4608753_4609827_+	hypothetical protein	Q7Y4B3	Escherichia_virus	1.2e-203	100.0
AUY31261.1\|4609831_4610857_+	hypothetical protein	Q7Y4B4	Escherichia_virus	3.3e-198	100.0
AUY31262.1\|4610853_4611792_-	Cytosine-specific methyltransferase	Q7Y4B5	Escherichia_virus	3.1e-187	100.0
AUY31263.1\|4612034_4612241_-	Phage protein	Q2P9X3	Enterobacteria_phage	2.4e-31	97.0
AUY31264.1\|4612240_4612693_-	ASCH domain protein	Q2P9X4	Enterobacteria_phage	1.4e-79	96.7
AUY31265.1\|4612692_4613226_-	hypothetical protein	Q7Y4B8	Escherichia_virus	2.0e-69	92.8
AUY31266.1\|4613289_4613790_-	hypothetical protein	M1SV55	Escherichia_phage	2.6e-92	100.0
AUY31267.1\|4613786_4613984_-	hypothetical protein	S4TNZ7	Salmonella_phage	1.8e-28	96.9
AUY31268.1\|4613959_4614232_-	hypothetical protein	Q1JS44	Enterobacteria_phage	1.5e-46	100.0
AUY31269.1\|4614384_4614678_+	Repressor	Q1JS45	Enterobacteria_phage	1.0e-48	100.0
AUY31270.1\|4614747_4615728_+	Integrase	U5N0A8	Enterobacteria_phage	2.3e-185	99.7
AUY31271.1\|4615913_4616414_-	Periplasmic protein CpxP	NA	NA	NA	NA
AUY31272.1\|4616563_4617262_+	two-component system, OmpR family, response regulator CpxR	Q6XM27	Feldmannia_irregularis_virus	5.3e-06	30.3
AUY31273.1\|4617258_4618632_+	two-component system, OmpR family, sensor histidine kinase CpxA	W8CYF6	Bacillus_phage	3.8e-16	25.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP026474

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2056 : 52577

Escherichia_phage(38.1%)

integrase,transposase,protease

attL 43977:44036|attR 54471:55786

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUY31458.1\|2056_2710_+\|protease	CAAX protease family protein	NA	NA	NA	NA
AUY31459.1\|2802_3060_+	Antitoxin PemI	NA	NA	NA	NA
AUY31460.1\|3061_3394_+	hypothetical protein	NA	NA	NA	NA
AUY31461.1\|5938_6643_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AUY31462.1\|6741_7341_+	fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5	NA	NA	NA	NA
AUY31463.1\|7426_8302_+	OXA-1 family class D beta-lactamase	NA	NA	NA	NA
AUY31464.1\|8439_8988_+	type B-3 chloramphenicol O-acetyltransferase CatB3	A0A1V0SJ47	Klosneuvirus	2.0e-08	38.0
AUY31465.1\|8933_9638_-\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AUY31466.1\|9684_11700_-\|transposase	transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	100.0
AUY31467.1\|12338_13214_-	class A extended-spectrum beta-lactamase	A0A1B0VBP7	Salmonella_phage	1.1e-125	82.4
AUY31468.1\|13595_14300_-	TnpA IS26 (1)	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AUY31469.1\|14884_15745_+	beta-lactamase class A TEM	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
AUY31470.1\|15855_18363_-\|transposase	transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	70.8
AUY31471.1\|18365_18926_-\|transposase	transposase	A0A1B0V7I5	Salmonella_phage	4.0e-49	86.2
AUY31472.1\|19498_20140_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
AUY31473.1\|20355_21027_-	hypothetical protein	NA	NA	NA	NA
AUY31474.1\|22559_23411_+	Replication protein C	NA	NA	NA	NA
AUY31475.1\|23718_24534_+	sulfonamide-resistant dihydropteroate synthase Sul2	A0A0B5J4J5	Pandoravirus	3.5e-09	27.6
AUY31476.1\|24594_25398_+	APH(3'') family aminoglycoside O-phosphotransferase	NA	NA	NA	NA
AUY31477.1\|25397_26234_+	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
AUY31478.1\|26294_26999_-\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AUY31479.1\|27138_27903_+\|transposase	IS6100 transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
AUY31480.1\|28395_28980_-	macrolide 2'-phosphotransferase I repressor A	NA	NA	NA	NA
AUY31481.1\|28979_30218_-	MFS transporter	NA	NA	NA	NA
AUY31482.1\|30214_31129_-	Mph(A) family macrolide 2'-phosphotransferase	NA	NA	NA	NA
AUY31483.1\|31250_31955_-\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AUY31484.1\|31991_33119_-	hypothetical protein	NA	NA	NA	NA
AUY31485.1\|33169_33397_-	hypothetical protein	NA	NA	NA	NA
AUY31486.1\|34093_34636_-	hypothetical protein	NA	NA	NA	NA
AUY31487.1\|34648_35509_-	aminoglycoside 3-N-acetyltransferase VI AAC(3)-Iia	NA	NA	NA	NA
AUY31488.1\|35651_36620_+\|transposase	transposase	A4KWT9	Enterobacteria_phage	2.5e-187	100.0
AUY31489.1\|36723_37590_+\|transposase	TnpA transposase of IS10	A4KWT9	Enterobacteria_phage	1.3e-163	100.0
AUY31490.1\|38765_39626_+	beta-lactamase class A TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
AUY31491.1\|39775_40201_+\|transposase	IS91 family transposase	NA	NA	NA	NA
AUY31492.1\|40212_40917_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AUY31493.1\|41318_42332_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
AUY31494.1\|43093_43882_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5	NA	NA	NA	NA
43977:44036	attL	NA	NA	NA	NA
AUY31495.1\|44428_45268_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
AUY31496.1\|45672_47214_+\|transposase	IS91 family transposase	NA	NA	NA	NA
AUY31497.1\|47526_48558_+	twin-arginine translocation (TAT) pathway signal sequence domain protein	NA	NA	NA	NA
AUY31498.1\|48568_49207_-	phosphoribosylanthranilate isomerase	NA	NA	NA	NA
AUY31499.1\|49211_49472_-	bleomycin resistance protein	NA	NA	NA	NA
AUY31500.1\|49580_50393_-	subclass B1 metallo-beta-lactamase NDM-5	NA	NA	NA	NA
AUY31501.1\|50951_51656_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AUY31502.1\|51689_52577_-\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	9.2e-56	42.2
54471:55786	attR	NA	NA	NA	NA

DBSCAN-SWA_2

62148 : 75184

Escherichia_phage(36.36%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUY31509.1\|62148_62514_+	Transposase	Q76S41	Shigella_phage	9.6e-60	100.0
AUY31510.1\|62471_63377_+	Transposase	Q9ZXG3	Shigella_phage	3.3e-178	99.7
AUY31511.1\|63843_64101_-	hypothetical protein	NA	NA	NA	NA
AUY31512.1\|64619_65360_+	Site-specific recombinase	I3WFA4	Macacine_betaherpesvirus	2.0e-24	57.6
AUY31513.1\|65644_66622_-	Protein RepA	J9Q7H0	Salmonella_phage	1.4e-100	59.2
AUY31514.1\|67754_68114_-	PdcB	A0A077SLM1	Escherichia_phage	5.0e-45	98.9
AUY31515.1\|68141_68321_-	PdcA protein	Q71TH5	Escherichia_phage	3.5e-23	96.6
AUY31516.1\|68325_68706_-	prevent-host-death family protein	A0A077SK56	Escherichia_phage	1.1e-63	100.0
AUY31517.1\|68705_68927_-	Antitoxin phd	A0A222YXU1	Escherichia_phage	6.7e-32	100.0
AUY31518.1\|69109_70666_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	7.1e-104	42.5
AUY31519.1\|70662_71946_+	type I restriction-modification system subunit S	F2Y1N5	Organic_Lake_phycodnavirus	2.2e-10	26.5
AUY31520.1\|72067_75184_+	type I restriction-modification system subunit R	A0A220A398	Liberibacter_phage	2.9e-27	24.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. CP026476

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

25786 : 43996

Escherichia_phage(33.33%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUY31676.1\|25786_26608_+\|protease	metalloprotease	NA	NA	NA	NA
AUY31677.1\|26717_26972_+	hypothetical protein	NA	NA	NA	NA
AUY31678.1\|26989_27265_+	hypothetical protein	NA	NA	NA	NA
AUY31679.1\|27261_27540_+	hypothetical protein	NA	NA	NA	NA
AUY31680.1\|27536_27683_+	hypothetical protein	NA	NA	NA	NA
AUY31681.1\|29725_29923_+	ArsR family transcriptional regulator	NA	NA	NA	NA
AUY31682.1\|29969_30674_+\|transposase	transposase	A0A077SL39	Escherichia_phage	3.1e-139	99.6
AUY31683.1\|31020_31188_+	hypothetical protein	NA	NA	NA	NA
AUY31684.1\|31194_31386_-\|transposase	IS2 transposase	Q76S41	Shigella_phage	5.4e-14	72.2
AUY31685.1\|31753_32410_+	quinolone resistance pentapeptide repeat protein QnrS1	NA	NA	NA	NA
AUY31686.1\|32728_33343_-	resolvase TniR	A0A0A7NPV4	Enterobacteria_phage	8.1e-35	47.4
AUY31687.1\|33504_33762_+\|transposase	transposase	NA	NA	NA	NA
AUY31688.1\|33822_34368_+	hypothetical protein	NA	NA	NA	NA
AUY31689.1\|34504_35077_+\|transposase	transposase	M9Q1K0	Clostridium_phage	3.4e-19	39.4
AUY31690.1\|35113_36505_+	hypothetical protein	NA	NA	NA	NA
AUY31691.1\|36468_37434_-	replication protein A	NA	NA	NA	NA
AUY31692.1\|38368_39166_-	carbapenem-hydrolyzing class D beta-lactamase OXA-181	NA	NA	NA	NA
AUY31693.1\|39786_42645_-	Transposase	A0A125RQ78	Bacillus_phage	5.2e-52	24.7
AUY31694.1\|43291_43996_+\|transposase	transposase IS26	A0A077SL39	Escherichia_phage	3.1e-139	99.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage