CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
CP027158	Klebsiella pneumoniae strain AR_0361 plasmid unnamed2, complete sequence	0 crisprs	NA	2
CP027162	Klebsiella pneumoniae strain AR_0361 plasmid unnamed3	0 crisprs	RT	1
CP027164	Klebsiella pneumoniae strain AR_0361 plasmid unnamed4	0 crisprs	NA	1
CP027157	Klebsiella pneumoniae strain AR_0361 plasmid unnamed6	0 crisprs	NA	0
CP027161	Klebsiella pneumoniae strain AR_0361 plasmid unnamed1, complete sequence	0 crisprs	RT,c2c9_V-U4,csa3,cas3	3
CP027163	Klebsiella pneumoniae strain AR_0361 plasmid unnamed5	0 crisprs	NA	0
CP027160	Klebsiella pneumoniae strain AR_0361 chromosome, complete genome	2 crisprs	DEDDh,WYL,DinG,RT,cas3,csa3	8
CP027159	Klebsiella pneumoniae strain AR_0361 plasmid unnamed7	0 crisprs	NA	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2 : 8788

Enterobacteria_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVK29869.1\|2_434_+	protein UmuD	A0A1W6JNS2	Morganella_phage	1.0e-28	52.5
AVK29870.1\|433_1705_+	IMS HHH motif family protein	F1C5A5	Cronobacter_phage	3.6e-154	63.7
AVK29815.1\|2105_3002_+	replication protein RepA	Q71TL8	Escherichia_phage	3.3e-69	53.8
AVK29789.1\|3386_4529_+	plasmid partition protein A	Q1MVJ3	Enterobacteria_phage	7.6e-196	90.0
AVK29797.1\|4525_5500_+	parB	Q1MVJ4	Enterobacteria_phage	1.4e-105	62.3
AVK29805.1\|6760_8788_+	hsdM N-terminal domain protein	A0A220A2U5	Liberibacter_phage	2.1e-26	26.6

DBSCAN-SWA_2

13363 : 48926

Escherichia_phage(33.33%)

holin,integrase,transposase

attL 6570:6584|attR 56344:56358

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
6570:6584	attL	NA	NA	NA	NA
AVK29866.1\|13363_14632_+\|transposase	helix-turn-helix domain of transposase ISL3 family protein	Q6V7R1	Burkholderia_virus	5.2e-60	34.7
AVK29775.1\|16438_17221_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	4.6e-51	90.2
AVK29756.1\|17220_17553_-	hypothetical protein	NA	NA	NA	NA
AVK29834.1\|17559_17958_-	hypothetical protein	NA	NA	NA	NA
AVK29771.1\|17983_18229_-	hypothetical protein	NA	NA	NA	NA
AVK29861.1\|18340_18613_-	hypothetical protein	NA	NA	NA	NA
AVK29793.1\|18694_18946_-	hypothetical protein	NA	NA	NA	NA
AVK29776.1\|19135_19570_-	hypothetical protein	NA	NA	NA	NA
AVK29798.1\|19553_19784_+	antidote-toxin recognition MazE family protein	NA	NA	NA	NA
AVK29831.1\|19795_20197_+	PIN domain protein	NA	NA	NA	NA
AVK29766.1\|20291_20981_+	AAA domain protein	NA	NA	NA	NA
AVK29792.1\|21334_21712_+\|transposase	putative transposase	Q71TF0	Escherichia_phage	1.9e-63	93.6
AVK29800.1\|21873_22296_+	merC mercury resistance family protein	NA	NA	NA	NA
AVK29770.1\|22392_24042_+	mercuric reductase	A0A2K5B2C5	Erysipelothrix_phage	8.5e-39	27.6
AVK29845.1\|24059_24422_+	mercuric resistance transcriptional repressor protein MerD	NA	NA	NA	NA
AVK29783.1\|24418_24655_+	merE family protein	NA	NA	NA	NA
AVK29868.1\|24651_25359_+	EAL domain protein	NA	NA	NA	NA
AVK29796.1\|25826_26702_+\|integrase	integrase core domain protein	NA	NA	NA	NA
AVK29822.1\|26748_27159_+\|transposase	transposase IS66 family protein	A0A077SL39	Escherichia_phage	1.9e-72	100.0
AVK29816.1\|27269_28130_-	beta-lactamase TEM	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
AVK29802.1\|29873_30578_-\|transposase	transposase IS66 family protein	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AVK29808.1\|30650_33548_+	hypothetical protein	A0A1B0V7H9	Salmonella_phage	2.7e-181	37.7
AVK29855.1\|33636_34257_+	resolvase, N terminal domain protein	A0A219Y912	Aeromonas_phage	2.0e-09	31.5
AVK29841.1\|34646_34766_+	putative membrane protein	NA	NA	NA	NA
AVK29762.1\|35055_35190_-	hypothetical protein	NA	NA	NA	NA
AVK29767.1\|35422_35782_-	hypothetical protein	A0A218MND9	uncultured_virus	3.6e-19	62.0
AVK29826.1\|35953_36175_-\|transposase	putative transposase	A0A1V0E8E1	Vibrio_phage	2.4e-13	64.3
AVK29787.1\|36285_37470_+	DDE_Tnp_1-associated family protein	NA	NA	NA	NA
AVK29779.1\|37746_39066_+	hypothetical protein	Q9MBP7	Staphylococcus_prophage	1.9e-12	24.2
AVK29780.1\|39315_40197_-	carbapenem-hydrolyzing beta-lactamase Sme-1	A0A1B0VBP7	Salmonella_phage	2.2e-73	52.2
AVK29807.1\|40484_41264_-	phoH-like family protein	A0A2L1IVB6	Escherichia_phage	2.5e-89	61.8
AVK29790.1\|41260_42286_-\|integrase	integrase core domain protein	A0A2L1IVA1	Escherichia_phage	1.4e-87	50.3
AVK29804.1\|42392_45422_-	hypothetical protein	NA	NA	NA	NA
AVK29760.1\|45531_47247_+\|integrase	phage integrase family protein	NA	NA	NA	NA
AVK29812.1\|48429_48738_+\|holin	choline kinase N terminus family domain protein	NA	NA	NA	NA
AVK29835.1\|48764_48926_+\|transposase	putative transposase	NA	NA	NA	NA
56344:56358	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP027162

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

6028 : 25717

Escherichia_phage(28.57%)

transposase,integrase

attL 5737:5796|attR 29882:30110

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
5737:5796	attL	NA	NA	NA	NA
AVK35114.1\|6028_6733_+\|transposase	transposase IS66 family protein	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AVK35115.1\|7988_8816_+	initiator Replication family protein	A0A222YYK1	Escherichia_phage	1.5e-23	31.1
AVK35116.1\|8992_9262_-	LWamide neuropeptides domain protein	NA	NA	NA	NA
AVK35117.1\|9676_10882_+	plasmid partition protein A	A0A077SL49	Escherichia_phage	2.4e-163	69.6
AVK35118.1\|10881_11856_+	parB	Q38420	Escherichia_phage	5.0e-87	54.1
AVK35119.1\|11937_13209_-	IMS HHH motif family protein	F1C5A5	Cronobacter_phage	5.4e-150	63.7
AVK35120.1\|13208_13640_-	protein UmuD	A0A1W6JNS2	Morganella_phage	1.6e-29	53.3
AVK35121.1\|14048_15533_+	reverse transcriptase family protein	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
AVK35122.1\|15878_16382_+\|transposase	putative transposase	U5P0U6	Shigella_phage	2.6e-84	89.8
AVK35123.1\|16510_16717_-	hypothetical protein	NA	NA	NA	NA
AVK35124.1\|16742_17744_-	hypothetical protein	NA	NA	NA	NA
AVK35125.1\|18147_19071_+\|transposase	transposase DDE domain protein	Q1MVF0	Enterobacteria_phage	1.8e-171	96.4
AVK35126.1\|19210_19345_-	putative stbA	NA	NA	NA	NA
AVK35127.1\|20178_20448_+\|transposase	transposase DDE domain protein	A0A1B0VFY5	Salmonella_phage	1.5e-38	98.7
AVK35128.1\|20444_23411_-	hypothetical protein	A0A1B0V7H9	Salmonella_phage	0.0e+00	100.0
AVK35129.1\|23414_23975_-	resolvase, N terminal domain protein	A0A1B0V7I5	Salmonella_phage	1.1e-59	100.0
AVK35130.1\|23963_24131_+	hypothetical protein	A0A1B0V7I9	Salmonella_phage	2.3e-24	98.2
AVK35131.1\|24150_24351_-	hypothetical protein	NA	NA	NA	NA
AVK35132.1\|24703_25717_-\|integrase	integron integrase family protein	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
29882:30110	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP027161

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

15391 : 56398

Macacine_betaherpesvirus(14.29%)

holin,transposase,integrase

attL 22433:22449|attR 53494:53510

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVK34946.1\|15391_16471_+\|integrase	integrase core domain protein	NA	NA	NA	NA
AVK34917.1\|17078_17255_-	hypothetical protein	NA	NA	NA	NA
AVK35098.1\|17401_18130_-	psiA family protein	NA	NA	NA	NA
AVK35105.1\|18126_18558_-	plasmid SOS inhibition family protein	NA	NA	NA	NA
AVK34971.1\|18624_20577_-	parB-like nuclease domain protein	G8DH78	Emiliania_huxleyi_virus	8.6e-22	26.0
AVK34999.1\|20730_20979_-	hypothetical protein	NA	NA	NA	NA
AVK34989.1\|21027_21483_-	single-stranded DNA-binding family protein	A0A0A0P1Q9	Enterobacteria_phage	2.5e-33	71.4
AVK35018.1\|22345_22909_-	methyltransferase small domain protein	A8HNV9	Thalassomonas_phage	1.3e-18	34.1
22433:22449	attL	NA	NA	NA	NA
AVK34985.1\|22956_24312_-	hypothetical protein	NA	NA	NA	NA
AVK34929.1\|24685_24913_-	hypothetical protein	NA	NA	NA	NA
AVK35019.1\|24876_25014_+	hypothetical protein	NA	NA	NA	NA
AVK34932.1\|25694_25997_-	putative membrane protein	NA	NA	NA	NA
AVK35000.1\|26046_26301_-	hot	H9C187	Pectobacterium_phage	1.2e-11	50.0
AVK35094.1\|26537_26963_-	antirestriction family protein	NA	NA	NA	NA
AVK35088.1\|27947_29432_-	reverse transcriptase family protein	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
AVK34968.1\|30017_30263_+	peptidase S24-like family protein	A0A1W6JNS2	Morganella_phage	1.8e-14	50.6
AVK35046.1\|30262_31534_+	IMS HHH motif family protein	F1C5A5	Cronobacter_phage	5.6e-155	63.7
AVK35031.1\|31672_31828_+	antitoxin, type II toxin-antitoxin system family protein	NA	NA	NA	NA
AVK35095.1\|31850_32708_-\|transposase	transposase, IS605 OrfB family	A0A1B0VCD8	Salmonella_phage	1.0e-128	80.9
AVK35023.1\|32704_32989_-\|transposase	putative transposase family protein	A0A1W6JP07	Morganella_phage	1.0e-40	86.8
AVK35096.1\|33523_34486_-	hypothetical protein	NA	NA	NA	NA
AVK35055.1\|34485_35457_-	protein SopB	I3WF22	Macacine_betaherpesvirus	4.1e-150	86.6
AVK35037.1\|35456_36575_-	cobQ/CobB/MinD/ParA nucleotide binding domain protein	A0A2I6B2X3	Macacine_betaherpesvirus	1.7e-216	98.4
AVK35044.1\|37644_38385_+	repFIB replication protein A	J9Q7H0	Salmonella_phage	1.4e-60	56.0
AVK35083.1\|39101_39842_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	5.4e-25	58.6
AVK34957.1\|40976_41933_+	diguanylate cyclase domain protein	G3MA91	Bacillus_virus	1.8e-12	30.6
AVK34967.1\|42335_43259_+\|transposase	transposase DDE domain protein	Q9MCT5	Escherichia_phage	2.1e-175	98.4
AVK35063.1\|45408_46245_+	EAL domain protein	NA	NA	NA	NA
AVK35100.1\|47227_48505_-	hypothetical protein	NA	NA	NA	NA
AVK34935.1\|48567_50571_-\|holin	transporter, betaine/carnitine/choline transporter family protein	A0A2I7QNT1	Vibrio_phage	9.7e-21	25.9
AVK34993.1\|50716_51220_-\|transposase	putative transposase	U5P0U6	Shigella_phage	1.6e-84	93.2
AVK35036.1\|51604_52486_-	HTH-like domain protein	Q9ZXG3	Shigella_phage	1.2e-100	63.2
AVK34981.1\|52443_52812_-\|transposase	transposase family protein	Q76S41	Shigella_phage	1.3e-43	75.4
AVK34974.1\|53009_53387_+\|transposase	putative transposase	Q71TF0	Escherichia_phage	1.3e-62	92.8
AVK35071.1\|53540_53945_+\|transposase	transposase family protein	NA	NA	NA	NA
53494:53510	attR	NA	NA	NA	NA
AVK35048.1\|54240_54672_-	silver-binding protein SilE	NA	NA	NA	NA
AVK34953.1\|54922_56398_-	heavy metal sensor kinase family protein	W8CYF6	Bacillus_phage	1.0e-27	30.1

DBSCAN-SWA_2

75994 : 115079

Escherichia_phage(33.33%)

integrase,transposase

attL 70412:70428|attR 110977:110993

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
70412:70428	attL	NA	NA	NA	NA
AVK35040.1\|75994_76309_-\|transposase	transposase family protein	NA	NA	NA	NA
AVK35106.1\|76799_77615_-\|transposase	helix-turn-helix domain of transposase ISL3 family protein	A9YX10	Burkholderia_phage	1.7e-11	25.9
AVK35053.1\|77730_78186_+	major intrinsic family protein	NA	NA	NA	NA
AVK34991.1\|78235_78733_-	acetyltransferase family protein	NA	NA	NA	NA
AVK34960.1\|79064_79391_+	helix-turn-helix domain protein	NA	NA	NA	NA
AVK35009.1\|79642_80101_+	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	6.6e-66	79.5
AVK34980.1\|80139_80655_+	RNA polymerase sigma factor, sigma-70 family protein	NA	NA	NA	NA
AVK34939.1\|80730_81093_+	arsenical resistance operon trans-acting repressor ArsD family protein	NA	NA	NA	NA
AVK34988.1\|81117_82452_+	arsenical pump-driving ATPase	NA	NA	NA	NA
AVK34978.1\|82481_82868_+	anion-transporting ATPase family protein	NA	NA	NA	NA
AVK34987.1\|82989_83526_+	acetyltransferase domain protein	NA	NA	NA	NA
AVK35072.1\|83558_83984_-	arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	2.3e-52	72.9
AVK34931.1\|83996_85286_-	arsenite/antimonite efflux pump membrane family protein	A0A2H4J144	uncultured_Caudovirales_phage	1.9e-171	74.0
AVK35008.1\|85333_87085_-	arsenical pump-driving ATPase	NA	NA	NA	NA
AVK34964.1\|87102_87465_-	arsenical resistance operon trans-acting repressor ArsD	NA	NA	NA	NA
AVK35012.1\|87514_87865_-	bacterial regulatory, arsR family protein	A0A2H4J145	uncultured_Caudovirales_phage	1.4e-23	50.9
AVK35027.1\|88222_88492_+	hypothetical protein	NA	NA	NA	NA
AVK34990.1\|88536_89055_+	putative ydeA	NA	NA	NA	NA
AVK35043.1\|89085_89580_+	hypothetical protein	NA	NA	NA	NA
AVK35004.1\|90025_90229_+	hemolysin expression-modulating protein Hha	NA	NA	NA	NA
AVK35042.1\|90610_90865_+	putative yaeB	NA	NA	NA	NA
AVK34973.1\|91976_93335_+\|integrase	integrase core domain protein	NA	NA	NA	NA
AVK34983.1\|93835_94447_-\|integrase	integrase core domain protein	A0A2I6AZV9	Macacine_betaherpesvirus	4.0e-42	45.9
AVK34927.1\|94557_94863_-\|transposase	putative transposase	NA	NA	NA	NA
AVK34998.1\|95177_96140_-	peptidase M48 family protein	NA	NA	NA	NA
AVK34992.1\|96126_96561_-	phosphate-starvation-inducible E family protein	NA	NA	NA	NA
AVK35103.1\|97113_97311_-	hypothetical protein	NA	NA	NA	NA
AVK34958.1\|97310_100106_-	AAA domain protein	K4FB40	Cronobacter_phage	5.2e-129	41.0
AVK35101.1\|100220_100790_-	hsp20/alpha crystallin family protein	NA	NA	NA	NA
AVK35061.1\|100808_100946_+	hypothetical protein	NA	NA	NA	NA
AVK35011.1\|102078_102207_-	hypothetical protein	NA	NA	NA	NA
AVK34965.1\|102330_102834_+\|transposase	putative transposase	U5P0U6	Shigella_phage	1.8e-88	92.2
AVK34994.1\|103092_104073_+	hypothetical protein	Q38213	Escherichia_phage	8.9e-185	99.1
AVK35025.1\|104538_105174_-	hypothetical protein	Q38213	Escherichia_phage	1.2e-33	52.8
AVK35054.1\|105281_106151_-	lysR substrate binding domain protein	NA	NA	NA	NA
AVK34969.1\|106144_107155_-	phosphonate dehydrogenase	A0A1V0SBV6	Catovirus	1.4e-15	25.1
AVK34979.1\|107163_107991_-	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
AVK35092.1\|107999_108809_-	phosphate/phosphite/phosphonate ABC transporter, periplasmic binding family protein	NA	NA	NA	NA
AVK35093.1\|108859_109420_-	ABC transporter family protein	G9BWD6	Planktothrix_phage	1.6e-13	38.4
AVK35045.1\|110028_110349_+	hypothetical protein	Q38213	Escherichia_phage	3.2e-27	52.9
AVK34976.1\|110542_111247_-\|transposase	transposase IS66 family protein	A0A077SL39	Escherichia_phage	1.8e-139	100.0
110977:110993	attR	NA	NA	NA	NA
AVK34919.1\|111397_112213_+	phosphotransferase enzyme family protein	A0A193DTG4	Autographa_californica_nuclear_polyhedrosis_virus	6.1e-163	100.0
AVK34923.1\|112402_113008_-\|transposase	transposase IS66 family protein	A0A077SL39	Escherichia_phage	6.4e-117	99.5
AVK34934.1\|113118_114384_-\|transposase	tn3 transposase DDE domain protein	A0A1B0V7H9	Salmonella_phage	5.4e-142	67.1
AVK34959.1\|114374_115079_+\|transposase	transposase IS66 family protein	A0A077SL39	Escherichia_phage	1.2e-138	99.6

DBSCAN-SWA_3

118417 : 180028

Escherichia_phage(21.74%)

integrase,bacteriocin,transposase

attL 145027:145044|attR 183163:183180

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVK35078.1\|118417_119182_-\|transposase	transposase IS66 family protein	A0A077SL39	Escherichia_phage	4.3e-86	65.7
AVK34928.1\|119408_119714_-	winged helix DNA-binding domain protein	NA	NA	NA	NA
AVK34947.1\|119724_120930_-	chromate transporter, chromate ion transporter family protein	NA	NA	NA	NA
AVK35081.1\|121416_122256_-	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
AVK35032.1\|122760_123552_-	nucleotidyltransferase domain protein	NA	NA	NA	NA
AVK35007.1\|124601_125615_+\|integrase	integron integrase family protein	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
AVK34977.1\|125967_126168_+	hypothetical protein	NA	NA	NA	NA
AVK35010.1\|126293_126854_+	resolvase, N terminal domain protein	A0A1B0V7I5	Salmonella_phage	4.0e-49	86.2
AVK34945.1\|126856_129823_+	hypothetical protein	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.6
AVK35024.1\|129889_130267_+	acetyltransferase family protein	NA	NA	NA	NA
AVK35022.1\|130467_131127_-	chloramphenicol acetyltransferase	G3CFL0	Escherichia_phage	8.4e-131	100.0
AVK34922.1\|131599_132103_+\|transposase	putative transposase	Q71TF0	Escherichia_phage	1.5e-95	100.0
AVK34961.1\|132334_133723_+	4Fe-4S single cluster domain protein	S5VT21	Leptospira_phage	6.3e-51	29.0
AVK35039.1\|133715_134828_+	4Fe-4S single cluster domain protein	S5WIP3	Leptospira_phage	1.5e-47	33.8
AVK34975.1\|136390_136738_+\|transposase	putative transposase	A0A0P0ZDM8	Stx2-converting_phage	2.0e-59	95.7
AVK35070.1\|136787_137762_+\|transposase	transposase IS66 family protein	A0A0P0ZBS5	Stx2-converting_phage	2.7e-149	91.8
AVK34944.1\|137806_138325_+\|transposase	putative transposase	A0A0P0ZEB3	Stx2-converting_phage	1.7e-86	90.1
AVK34930.1\|138392_138740_+\|transposase	putative transposase	A0A0P0ZEB3	Stx2-converting_phage	2.6e-62	98.3
AVK35033.1\|140560_142294_-	nickel import ATP-binding protein NikE	G9BWD6	Planktothrix_phage	6.9e-15	29.6
AVK35047.1\|142301_143231_-	acetamidase/Formamidase family protein	A0A1V0S8X7	Catovirus	9.4e-11	22.7
AVK35049.1\|143293_144898_-	bacterial extracellular solute-binding, 5 Middle family protein	NA	NA	NA	NA
AVK35073.1\|144910_145831_-	binding-protein-dependent transport system inner membrane component family protein	NA	NA	NA	NA
145027:145044	attL	NA	NA	NA	NA
AVK34984.1\|145830_146679_-	N-terminal TM domain of oligopeptide transport permease C family protein	NA	NA	NA	NA
AVK35086.1\|146675_147269_-	response regulator	NA	NA	NA	NA
AVK35058.1\|147265_148393_-	periplasmic binding family protein	NA	NA	NA	NA
AVK35069.1\|148677_148845_-\|integrase	putative integrase catalytic region	NA	NA	NA	NA
AVK35090.1\|149103_149472_+	putative tnpA	U5N3F9	Enterobacteria_phage	2.4e-58	89.9
AVK34954.1\|149947_150469_+	putative RNA polymerase sigma factor FecI	NA	NA	NA	NA
AVK35017.1\|150465_151419_+	fecR family protein	NA	NA	NA	NA
AVK35021.1\|151504_153829_+	fe(3+) dicitrate transport protein FecA	NA	NA	NA	NA
AVK35015.1\|153873_154776_+	periplasmic binding family protein	NA	NA	NA	NA
AVK34926.1\|154772_155771_+	ABC 3 transport family protein	NA	NA	NA	NA
AVK34972.1\|155767_156724_+	fe(3+) dicitrate transport system permease protein FecD	NA	NA	NA	NA
AVK34936.1\|156724_157492_+	ABC transporter family protein	G3M9Y6	Bacillus_virus	9.8e-14	25.2
AVK34995.1\|157590_157884_+\|transposase	putative transposase	A0A0P0ZDM8	Stx2-converting_phage	2.7e-49	96.9
AVK35013.1\|157931_158051_-	hypothetical protein	NA	NA	NA	NA
AVK34925.1\|158835_159846_-	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
AVK34970.1\|159868_160084_-	hypothetical protein	NA	NA	NA	NA
AVK34950.1\|160306_161389_+	periplasmic binding and sugar binding domain of LacI family protein	C6ZCU4	Enterobacteria_phage	6.8e-186	96.4
AVK34996.1\|161516_164585_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	96.7
AVK35001.1\|164666_165890_+	lactose permease	NA	NA	NA	NA
AVK35060.1\|166026_166638_+\|transposase	transposase DDE domain protein	Q9MCT5	Escherichia_phage	3.5e-99	99.4
AVK35059.1\|166741_166951_+\|transposase	transposase family protein	Q9MCT5	Escherichia_phage	4.1e-31	98.6
AVK35068.1\|167595_169905_+	tellurite resistance TerB family protein	NA	NA	NA	NA
AVK34966.1\|169908_171225_+	hypothetical protein	NA	NA	NA	NA
AVK34963.1\|171221_173417_+	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
AVK35076.1\|174863_175721_-	incFII family plasmid replication initiator RepA	NA	NA	NA	NA
AVK35066.1\|176606_177086_-	endonuclease	A0A1B2LRT6	Wolbachia_phage	9.8e-20	35.2
AVK35082.1\|177706_180028_-\|bacteriocin	DNase/tRNase domain of colicin-like bacteriocin family protein	NA	NA	NA	NA
183163:183180	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. CP027164

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

54 : 5446

Escherichia_phage(83.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVK35149.1\|54_915_+	beta-lactamase SHV-2	A0A077SL40	Escherichia_phage	2.2e-155	99.3
AVK35150.1\|935_1697_-	HTH domain protein	A0A077SK06	Escherichia_phage	1.9e-134	100.0
AVK35151.1\|1958_2861_+	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain protein	A0A077SLF7	Escherichia_phage	2.6e-159	99.7
AVK35152.1\|2872_3505_+	hypothetical protein	A0A077SLJ7	Escherichia_phage	8.5e-96	98.9
AVK35153.1\|3501_4083_+	hypothetical protein	A0A077SLJ7	Escherichia_phage	8.3e-82	98.2
AVK35154.1\|4069_5446_-\|transposase	tn3 transposase DDE domain protein	A0A125RQ78	Bacillus_phage	7.3e-44	30.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. CP027160

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP027160_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP027160_1

720594-720671

Orphan

Consensus_repeat	Method
AAGGCGTCAGCCGCCGCCCGGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP027160_1

>merge|CP027160|1|720594-720671|CRISPRCasFinder
AAGGCGTCAGCCGCCGCCCGGCAAAATAACCGCGCAATAGCACCGTAGGCCGGGCAAGGCGTCAGCCGCCGCCCGGCA

>CP027160|1|1|720594-720671|CRISPRCasFinder
AAGGCGTCAGCCGCCGCCCGGCA	AAATAACCGCGCAATAGCACCGTAGGCCGGGC
AAGGCGTCAGCCGCCGCCCGGCA

Protein	Signature genes	Signature genes Name	Protein_function
CP027160.1\|AVK30380.1\|710712_711996_-\|putative-acyl-CoA-thioester-hydrolase-YbhC	unknown	unknown	gnl\|CDD\|236709
CP027160.1\|AVK33128.1\|725799_726522_+\|dethiobiotin-synthase	unknown	unknown	gnl\|CDD\|234625
CP027160.1\|AVK32577.1\|713466_714423_+\|formimidoylglutamase	unknown	unknown	gnl\|CDD\|234974
CP027160.1\|AVK34620.1\|720823_721300_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182339
CP027160.1\|AVK32903.1\|725051_725807_+\|ubiE/COQ5-methyltransferase-family-protein	unknown	unknown	gnl\|CDD\|182340
CP027160.1\|AVK30201.1\|731267_731939_-\|transcriptional-regulatory-protein-BasR	unknown	unknown	gnl\|CDD\|182612
CP027160.1\|AVK30623.1\|727272_727485_-\|hypothetical-protein	unknown	unknown	unknown
CP027160.1\|AVK31438.1\|730166_731264_-\|sensor-protein-BasS	unknown	unknown	gnl\|CDD\|236751
CP027160.1\|AVK34873.1\|715352_717041_+\|urocanate-hydratase	unknown	unknown	gnl\|CDD\|235448
CP027160.1\|AVK33552.1\|721370_722603_-\|adenosylmethionine-8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|181189
CP027160.1\|AVK31459.1\|723910_725068_+\|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl\|CDD\|235655
CP027160.1\|AVK33123.1\|708570_709077_+\|hypothetical-protein	unknown	unknown	unknown
CP027160.1\|AVK34509.1\|710031_710439_+\|cation-transporting-ATPase,-family-protein	unknown	unknown	gnl\|CDD\|319775
CP027160.1\|AVK32610.1\|722897_723914_+\|biotin-synthase	unknown	unknown	gnl\|CDD\|185063
CP027160.1\|AVK33433.1\|718662_720045_+\|amino-acid-permease-family-protein	unknown	unknown	gnl\|CDD\|182566
CP027160.1\|AVK32088.1\|717037_718564_+\|histidine-ammonia-lyase	unknown	unknown	gnl\|CDD\|236484
CP027160.1\|AVK31420.1\|727896_729918_+\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
CP027160.1\|AVK32750.1\|714484_715210_+\|histidine-utilization-repressor	unknown	unknown	gnl\|CDD\|184961
CP027160.1\|AVK31252.1\|712252_713470_+\|imidazolonepropionase	unknown	unknown	gnl\|CDD\|236478
CP027160.1\|AVK32373.1\|709093_710017_-\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|225813

Protein	Function_ID	Function_description	E-value
CP027160.1\|AVK30380.1\|710712_711996_-\|putative-acyl-CoA-thioester-hydrolase-YbhC	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
CP027160.1\|AVK33128.1\|725799_726522_+\|dethiobiotin-synthase	gnl\|CDD\|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	4.52132e-105
CP027160.1\|AVK32577.1\|713466_714423_+\|formimidoylglutamase	gnl\|CDD\|234974	PRK01722, PRK01722, formimidoylglutamase; Provisional.	8.10638e-178
CP027160.1\|AVK34620.1\|720823_721300_-\|hypothetical-protein	gnl\|CDD\|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	7.58373e-117
CP027160.1\|AVK32903.1\|725051_725807_+\|ubiE/COQ5-methyltransferase-family-protein	gnl\|CDD\|182340	PRK10258, PRK10258, biotin biosynthesis protein BioC; Provisional.	1.7976e-160
CP027160.1\|AVK30201.1\|731267_731939_-\|transcriptional-regulatory-protein-BasR	gnl\|CDD\|182612	PRK10643, PRK10643, two-component system response regulator PmrA.	2.78247e-146
CP027160.1\|AVK31438.1\|730166_731264_-\|sensor-protein-BasS	gnl\|CDD\|236751	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB.	0
CP027160.1\|AVK34873.1\|715352_717041_+\|urocanate-hydratase	gnl\|CDD\|235448	PRK05414, PRK05414, urocanate hydratase; Provisional.	0
CP027160.1\|AVK33552.1\|721370_722603_-\|adenosylmethionine-8-amino-7-oxononanoate-transaminase	gnl\|CDD\|181189	PRK07986, PRK07986, adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated.	0
CP027160.1\|AVK31459.1\|723910_725068_+\|8-amino-7-oxononanoate-synthase	gnl\|CDD\|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	0
CP027160.1\|AVK34509.1\|710031_710439_+\|cation-transporting-ATPase,-family-protein	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	2.27037e-48
CP027160.1\|AVK32610.1\|722897_723914_+\|biotin-synthase	gnl\|CDD\|185063	PRK15108, PRK15108, biotin synthase; Provisional.	0
CP027160.1\|AVK33433.1\|718662_720045_+\|amino-acid-permease-family-protein	gnl\|CDD\|182566	PRK10580, proY, putative proline-specific permease; Provisional.	0
CP027160.1\|AVK32088.1\|717037_718564_+\|histidine-ammonia-lyase	gnl\|CDD\|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0
CP027160.1\|AVK31420.1\|727896_729918_+\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP027160.1\|AVK32750.1\|714484_715210_+\|histidine-utilization-repressor	gnl\|CDD\|184961	PRK14999, PRK14999, histidine utilization repressor; Provisional.	3.37417e-172
CP027160.1\|AVK31252.1\|712252_713470_+\|imidazolonepropionase	gnl\|CDD\|236478	PRK09356, PRK09356, imidazolonepropionase; Validated.	0
CP027160.1\|AVK32373.1\|709093_710017_-\|acyltransferase-family-protein	gnl\|CDD\|225813	COG3274, COG3274, Predicted O-acyltransferase [General function prediction only].	6.63632e-09

>CP027160.1|AVK33433.1|718662_720045_+|amino-acid-permease-family-protein
MQQQHKPHLLRGLNARHIRFIALGSAIGTGLFYGSASAIKAAGPAVLLAYLIGGAAVFIVMRALGEMAVRNPVSGSFGSYARQYLGPLAGFITGWTYTFEMVIVALADVTAFGIYMGLWYPDVPRWIWILSIIFFIGAMNLCNVRVFGEMEFWLSLVKVVAIIAMMLAGAGIIFFGFGHSFPATGLENLWSHGGFAPNGWQGVIASLGIVMFAFGGVEIIGVTAAEAKDPKKVIPQAINTIPLRIILFYVCTLAVLMAIFPWNSFGEQGSPFVLIFDGLGIPAAATILNIIVISASISAINSDIFGAGRMMYGMSKEGLAPKSFQRIASNGVPWMTVVVMGGALLAAVVLNYLIPEQVFVLIASLAAFATVWVWLMILLSHFAMRRGLSAEERSQIAFPIPFWPVAPLLTLLFMGLVIAVLGMFAETRMALIAGLVWLGLLTVVWYARVRKTALQVATEQ
>CP027160.1|AVK32088.1|717037_718564_+|histidine-ammonia-lyase
MKSLTLIPGQLSLSQLRDVYSHPVNITLDSGAFAAIDESVACVNAILAEGRTAYGINTGFGLLAQTRISTEDLENLQRSLVLSHAAGVGEPLDDDLTRLIMVLKINSLSRGFSGIRLSVIQALIGLVNAGVTPWIPAKGSVGASGDLAPLAHMSLTLLGEGKARVRGGEWLPATEALRQVGLEPITLAAKEGLALLNGTQASTAFALRGLFEAEDLFASAVVCGALTTEAALGSRRPFDARIHEVRGQRGQIDAAALYRHLLTDDSAISQSHHNCSKVQDPYSLRCQPQVMGACLTQIRQAAEVLLAEANAVSDNPLVFAAENDVISGGNFHAEPVAMAADNIALAIAEIGSLSERRIALMMDSHMSQLPPFLVKNGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGRRLWAMAENTRGVLAVEWLAAAQGLDMREGLTTSPLLEEARHLLRERVPHYTQDRYFAPDIDNAIALLAARHLTRLLPAVLH
>CP027160.1|AVK34873.1|715352_717041_+|urocanate-hydratase
MSQSKYRQLDVRAPRGTTLTAKSWLTEAPLRMLMNNLDPDVAENPHELVVYGGIGRAARNWECYDAIVKALKNLESDETLLVQSGKPVGVFKTHENSPRVLIANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYQGSLKGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLRTRYVDEQATSLDDALARIKKYTAEGRAISIALCGNAAEIVPELVKRGVRPDMVTDQTSAHDPLHGYLPKGWSWEEYQQKAESDPQGTILAAKRSMADHVQAMLAFHEMGVPTFDYGNNIRQMAQEVGVSNAFDFPGFVPAYIRPLFCRGIGPFRWVALSGDPQDIYKTDAKVKEIIKDDQHLHHWLDMARERISFQGLPARICWVGLEWRQKLGLAFNEMVRSGEVSAPIVIGRDHLDSGSVASPNRETEAMRDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDEAAARIARVLHNDPATGVMRHADAGYEIAIECAAEQGLNLPMVAATQGNAK
>CP027160.1|AVK32750.1|714484_715210_+|histidine-utilization-repressor
MFAQQPRSAPAPFYEKVKQAISEKIHSGVWRPHDRIPSEAELVAQFGFSRMTINRALRELTDEGLLVRLQGVGTFVAEPKGQSALFEVRSIAAEIVARHHQHRCEVLLLEETRADHIQATALSVPEGTRIFHSLMVHYENEVPVQIEDRCVNAAVVPDYLHQDYTATTPHDYLSLIAPLTEGEHIVEAVQATAEECALLHIHAHDPCLLIRRRTWSTTHIVSHARLLFPGSRYRLQGRFGS
>CP027160.1|AVK32577.1|713466_714423_+|formimidoylglutamase
MMLWQATPASLWQGRDDSAEAPNALRLFQTIVRAERFAPQEMPGDIALLGFACDEGVRRNKGRTGAADGPATLRRALANMASHQGHDRCVDMGTISVDGEQLEAAHQALREAVADCQRVGKRTLVLGGGHETAFGHGAGVLDAFPGEKVGIINLDAHLDLRFADCASSGTPFRQLALECDAQQRGFHYTCIGVSRAANTQALWDEAARRQVAIVEDLEVLTAFETRVLPELERNIAQFDRLYLTIDLDVLPAREMPAVSAPAALGVPLATLLRIVEPLCRNGKLQAVDLVEFNPLFDIDGQGARAAARLAWQIAHWWR
>CP027160.1|AVK31252.1|712252_713470_+|imidazolonepropionase
MTEATSELVIWRNGRLATLNPDHAQPYGLLERHALLVRDGRIAAIVAEDDVPSGRSIDLEGRLVTPGLIDCHTHLVFGGSRAQEWEQRLNGVSYQTISASGGGINSTVRATRDSSEAELLALAQPRLERLLREGVTTLEIKSGYGLDLPNERKMLRVARQLADHNGVELSATLLSAHATPPEYQGDADGYITLVCETILPTLWQEGLFESVDVFCENVGFSPQQTERVFQAAQALGIPVKGHVEQLSSLGGAQLVSRYHGLSADHIEYLTEEGVAAMRESGTVAALLPGAFYFLNETRKPPVELLRKYQVPMAVATDFNPGTSPFASLHLAMNMACVKFGLTPEEAWAGVTRHAARALGRQASHGQLAPGFVANFAIWDAEHPVEMVYEPGRSPLWHRVVQGELQ
>CP027160.1|AVK30380.1|710712_711996_-|putative-acyl-CoA-thioester-hydrolase-YbhC
MNTYSVSRLALALAFGVTLSACSSTPADQQPSTQTAPGTTARPILNAEEAKNFTPAAYFQSLAPNAAAWTPSAISLPAQPDFIVGPAGTQGVTHTTIQAAVDAAIARHSNRRLYIAIMPGEYPGTVYVPAAPGALTLYGTGDKPIDVKISEAIDSEMDRNTWRRLVNPGGKYMPGKPAWYMFDSCQSKSAATIGVMCSAVFWSQNNGLQLQNLTIANNLGDSVDAGTHQAVALRSDGDQVQINKVNILGRQNTFFVTNSGVQNRLQDNRQTRTLVTNSYIEGDVDIVSGRGAVVFDNTDFRVVNSRTQKEAYVFAPATLKSVTYGFLATNSRFTASGDNVAQLGRALDVDGNSNGQVVIRDSAINEGFNIAQPWAAAVGSGRPFSGNTGSADDKGNLQRNLNDNGFNRMWEYNNRGVGSTVVAEPKQ
>CP027160.1|AVK34509.1|710031_710439_+|cation-transporting-ATPase,-family-protein
MDGFAIWRVAFVGSMIAVSAFILEAWLQPRGYSPEFIRTVLLQTLVTAQWFYMLNCRVSDGFSLTKGLLANKGIWIVSGVLLVLQLLIIYAPFMQMLFGTTGLPFRYWVITFIIGFAMFLIVELEKPLTRKWRSA
>CP027160.1|AVK32373.1|709093_710017_-|acyltransferase-family-protein
MTAVTFFTIYNTWDRFDYDYHWILGLLTFISTIATPLFFVVAGYLDAQTRHDANWQIGKIKSVVIVFLFWVTVYYVWEPYQRGYLIQPWFIFALIVIYTFHPLIAWLSQRRGLFFAVLLTLLCCSYGYDLLSVIYPDRHLFSLPPQYRLWTWLLFYLTGQLFNDPKVAEWIRNPQVIKGSIIALPFVYLFTWFYERHFFFALFKADRNAFILTGSQIYILIVLLVIAANAVQFKKNREWKEAVLATVSKAMTGVYILHYSVFHLLVMLIPVHSLATKLGVIALTFVLSVLISLAALSSTLLRKVITL
>CP027160.1|AVK33123.1|708570_709077_+|hypothetical-protein
MRGKSVMLLAGLASLAQANELNLYSVNTGSYVYHLTNNHGQYTENFENHFFSVERKFSADSKYSLLLGTMNNSFNDRCLALGVRRDWYHSGSGWTFKGVYGYTGEFFFDAFEHCGDHGSYKDFKDATGIGFSPYIYHAIQYNFTDYFAVESGIIIPSVFVISIQWSFR
>CP027160.1|AVK34620.1|720823_721300_-|hypothetical-protein
MKLISHDLQDGGKLPNRHVFNGMGYDGDNISPHLMWDDVPAGTKSFVVTCYDPDAPTGSGWWHWVVANLPADTRVLPQGAGSGQAELPEEAVQTRTDFGKAGYGGAAPPKGETHRYIFTVHALDVEKIEVDAEASGAMVGFNVHFHSLASASITALFS
>CP027160.1|AVK33552.1|721370_722603_-|adenosylmethionine-8-amino-7-oxononanoate-transaminase
MTSPLPVYPVVSAHGCELSLAGGEQLVDGMSSWWAAIHGYNHPRLNAALKGQIDQMSHVMFGGITHPPAVALCRQLVAMTPASLECVFLADSGSVAVEVAMKMALQYWQAKGEPRRRFLTFRNGYHGDTFGAMSVCDPQNSMHSLWQGYLPDNLFAPAPQSRFDGEWDEMDMVPFARLMAAHRHEIAAVILEPIVQGAGGMRMYHPEWLKRVRKMCDREGILLIADEIATGFGRTGKLFACEHAGITADILCLGKALTGGTMTLSAAITTRTVAETISNGEAGCFMHGPTFMGNPLACAVAGESLRLLESGEWQPQVTAIEAQLQAELAPARGSALVADVRVLGAIGVVETRRPVNMAALQRFFVEQGVWIRPFGRLIYLMPPYIITPEQLTRLTRAVNQAVQDETFFSE
>CP027160.1|AVK32610.1|722897_723914_+|biotin-synthase
MSQVTELFNKPLIDLLFEAQQIHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSARYKTGLEAERLMEVEQVLESARQAKNAGSTRFCMGAAWKNPNDRDMPYLEQMVKGVKALGLESCMTLGTLTDSQAQRLAEAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLDKVRDAGIKVCSGGIVGLGESVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAIARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGINPQQTAVLEGDNEQQQRLEQALLTPDTEEYYNAAAL
>CP027160.1|AVK31459.1|723910_725068_+|8-amino-7-oxononanoate-synthase
MSWQQRIDRALDERRAAEAFRRRLPVTHGAGRWLEREGERWLNFSSNDYLGLSQHPAIIAAWQQGATRYGVGAGGSGHVSGYSEAHRALEEALVDWLGYPRALLFISGFAANQALIAALVEKDDRIVADRLSHASLLEAASLSPAQLRRFTHNDPQQLAQLLAKPLAGEQLAVTEGIFSMDGDSAPLAAIHAATQAAGAVLLVDDAHGVGVVGDEGRGSCAAQAVRPELLVVTFGKAFGVSGAAVLCDEAMADYLLQFARHLIYSTAMPPAQAVALSAALGIIRSDEGRQRRDILAARIRQFREGMGKVSLGLTDSVSAIQPLIVGDNARALNLACRLRDAGCWATAIRPPTVPVGSARLRLTLTAAHHAEDINRLLEVLHGHSE
>CP027160.1|AVK32903.1|725051_725807_+|ubiE/COQ5-methyltransferase-family-protein
MATVNKQAVAAAFGRAASGYTQHDELQRRCADLLLRQLARRDFAQVLDAGCGPGSMSRYWREAGSVVTALDLSAGMLAQAQRNDAAQHYLLGDIEALPLPDACVDLAWSNLAVQWCDDLRAAIGELYRVARPGGRVAFSTLLADSLPELNQAWQAIDDRPHANRFLSEAAVRAALSGLRATGEVHQISLPFADALSAMRSLKGIGATHLHQGRTAAPLGRGKLRELQLAWPQRQGICPLTYSLFTGVIERD
>CP027160.1|AVK33128.1|725799_726522_+|dethiobiotin-synthase
MTKRFFVTGTDTEVGKTIASSALLQAANLLGFHTAGYKPVASGSELTGDGLRNEDALALQRHSRVALRYDQVNPYTFAEPTSPHIISADEGRPIAAARLSSGLRELEGLADWVLVEGAGGWFTPLSDSLTFADWAQAEQLPVILVVGVKLGCINHAMLTAQAVRQAGLPLAGWIANDVQPPGKRHAEYLATLKNRLAAPFLGEIPWLADIAQRDDLGQYLDLRALDPALSTAPAAAHPAP
>CP027160.1|AVK30623.1|727272_727485_-|hypothetical-protein
MDNCPQPKTTAARRLSPFAVNRVAKNFYRTIFDNYPLKAARFLLLFAPPFSVGHRKSAAPALTRPDGIGV
>CP027160.1|AVK31420.1|727896_729918_+|excinuclease-ABC-subunit-B
MSKSFVLHSAFRPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKALLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMLIDQRAILRRLAELQYTRNDQAFQRGTFRVRGEVIDVFPAESDDIALRIELFDEEVERLSLFDPLTGHVEGTVPRYTIYPKTHYVTPRERIVQAMEEIKLELAERRKVLLANNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVIDESHVTVPQIGGMYRGDRARKETLVEYGFRLPSALDNRPMKFEEFEALAPQTIYVSATPGAYELDKSGGEVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRLRTAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQRYNEEHGIVPQGLNKKVVDILQLGQGLAKTKAKGRGKAKAVEPAGLSAVDMTPKALQQKIHELEGQMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
>CP027160.1|AVK31438.1|730166_731264_-|sensor-protein-BasS
MALFATETWTMRHRLLLTIGAILVVCQLISVFWLWHESKEQIQLLVASAIEGHNNQKHVEHEVREAVASLLVPSLLIVGLALYISMLAVRKITRPLSRLQSELENRTPDNLTPIVLSESVPEVTAVTTALNQLVSRLNLTLDRERLFTADVAHELRTPLAGLRLHLELLAKVHGMGVDPLIQRLDQMTTSISQLLQLARVGQSFSAGSYQQVLLLDDVVKPLQDELEAMLAQRQQRLLLTDIENEAVVSGDATLIGVILRNLVENAHRYSPEGSTIRVSVKAGLMPVMAVEDEGPGIDEAKSGELSKAFVRMDSRYGGIGLGLSIVTRIAQLHDAQFFLHNRQPGPGVRAWVLFPQRGGQNVSTH
>CP027160.1|AVK30201.1|731267_731939_-|transcriptional-regulatory-protein-BasR
MKILVIEDDALLLQGLILAMQSEGYVCDGVSTAHEAALSLASNHYSLIVLDLGLPDEDGLHFLSRMRREKMTQPVLILTARDTLEDRISGLDTGADDYLVKPFALEELNARIRALLRRHNNQGDNEISVGNLRLNVTRRLVWLGETALDLTPKEYALLSRLMMKAGSPVHREILYNDIYSWDNEPATNTLEVHIHNLREKIGKSRIRTVRGFGYMLANNIDTE

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Crispr_ID: CP027160_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP027160_2

5094391-5094476

Orphan

Consensus_repeat	Method
AATAAAAACCATAAAAACCACAGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP027160_2

>merge|CP027160|2|5094391-5094476|CRISPRCasFinder
AATAAAAACCATAAAAACCACAGTCATAAATCAGAGATATATCACTCCCGGGCAGTTCAGCGAATAAAAACCATAAAAACCATAGT

>CP027160|2|2|5094391-5094476|CRISPRCasFinder
AATAAAAACCATAAAAACCACAGT	CATAAATCAGAGATATATCACTCCCGGGCAGTTCAGCG
AATAAAAACCATAAAAACCATAGT

Protein	Signature genes	Signature genes Name	Protein_function
CP027160.1\|AVK32361.1\|5097403_5100247_-\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
CP027160.1\|AVK31538.1\|5084096_5084945_-\|bis(5'-nucleosyl)-tetraphosphatase	unknown	unknown	gnl\|CDD\|273208
CP027160.1\|AVK33836.1\|5086147_5087137_-\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
CP027160.1\|AVK34427.1\|5085329_5086151_-\|dimethyladenosine-transferase	unknown	unknown	gnl\|CDD\|234708
CP027160.1\|AVK29969.1\|5107267_5107438_-\|hypothetical-protein	unknown	unknown	unknown
CP027160.1\|AVK33284.1\|5088483_5090832_-\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
CP027160.1\|AVK31759.1\|5094573_5095938_+\|citrate/malate-transporter	unknown	unknown	gnl\|CDD\|377030
CP027160.1\|AVK33577.1\|5091935_5092634_-\|transcriptional-regulator-family-protein	unknown	unknown	gnl\|CDD\|226931
CP027160.1\|AVK32023.1\|5100497_5102855_-\|DNA-polymerase-family-B,-exonuclease-domain-protein	unknown	unknown	gnl\|CDD\|235595
CP027160.1\|AVK33132.1\|5103030_5103726_-\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
CP027160.1\|AVK34758.1\|5105376_5107086_-\|L-ribulokinase	unknown	unknown	gnl\|CDD\|235221
CP027160.1\|AVK32736.1\|5092623_5094249_-\|sensor-histidine-kinase-CitA	unknown	unknown	gnl\|CDD\|225827
CP027160.1\|AVK33180.1\|5096731_5097391_-\|pseudouridine-synthase,-RluA-family-protein	unknown	unknown	gnl\|CDD\|236659
CP027160.1\|AVK31316.1\|5083361_5083841_+\|dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714
CP027160.1\|AVK32612.1\|5103863_5105366_-\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
CP027160.1\|AVK30093.1\|5096117_5096657_+\|holo-ACP-synthase-CitX	unknown	unknown	gnl\|CDD\|163145
CP027160.1\|AVK33920.1\|5107423_5108269_+\|arabinose-operon-regulatory-protein	unknown	unknown	gnl\|CDD\|236717
CP027160.1\|AVK33300.1\|5091075_5091903_+\|dnaJ-like-protein-DjlA	unknown	unknown	gnl\|CDD\|236512
CP027160.1\|AVK34617.1\|5084949_5085309_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|180098
CP027160.1\|AVK34802.1\|5087142_5088429_-\|chaperone-SurA	unknown	unknown	gnl\|CDD\|236758

Protein	Function_ID	Function_description	E-value
CP027160.1\|AVK32361.1\|5097403_5100247_-\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
CP027160.1\|AVK31538.1\|5084096_5084945_-\|bis(5'-nucleosyl)-tetraphosphatase	gnl\|CDD\|273208	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical). Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a regulatory metabolite of stress conditions. It is hydrolyzed to two ADP by this enzyme. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase. [Cellular processes, Adaptations to atypical conditions].	0
CP027160.1\|AVK33836.1\|5086147_5087137_-\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
CP027160.1\|AVK34427.1\|5085329_5086151_-\|dimethyladenosine-transferase	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	3.65731e-147
CP027160.1\|AVK33284.1\|5088483_5090832_-\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
CP027160.1\|AVK31759.1\|5094573_5095938_+\|citrate/malate-transporter	gnl\|CDD\|377030	pfam03390, 2HCT, 2-hydroxycarboxylate transporter family. The 2-hydroxycarboxylate transporter family is a family of secondary transporters found exclusively in the bacterial kingdom. They function in the metabolism of the di- and tricarboxylates malate and citrate, mostly in fermentative pathways involving decarboxylation of malate or oxaloacetate.	4.87969e-169
CP027160.1\|AVK33577.1\|5091935_5092634_-\|transcriptional-regulator-family-protein	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	5.03078e-66
CP027160.1\|AVK32023.1\|5100497_5102855_-\|DNA-polymerase-family-B,-exonuclease-domain-protein	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
CP027160.1\|AVK33132.1\|5103030_5103726_-\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	0
CP027160.1\|AVK34758.1\|5105376_5107086_-\|L-ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
CP027160.1\|AVK32736.1\|5092623_5094249_-\|sensor-histidine-kinase-CitA	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	6.55037e-173
CP027160.1\|AVK33180.1\|5096731_5097391_-\|pseudouridine-synthase,-RluA-family-protein	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	2.4454e-161
CP027160.1\|AVK31316.1\|5083361_5083841_+\|dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.71656e-127
CP027160.1\|AVK32612.1\|5103863_5105366_-\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
CP027160.1\|AVK30093.1\|5096117_5096657_+\|holo-ACP-synthase-CitX	gnl\|CDD\|163145	TIGR03124, citrate_citX, holo-ACP synthase CitX. Members of this protein family are the CitX protein, or CitX domain of the CitXG bifunctional protein, of the citrate lyase system. CitX transfers the prosthetic group 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA to the citrate lyase gamma chain, an acyl carrier protein. This enzyme may be designated holo-ACP synthase, holo-citrate lyase synthase, or apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. In a few genera, including Haemophilus, this protein occurs as a fusion protein with CitG (2.7.8.25), an enzyme involved in prosthetic group biosynthesis. This CitX family is easily separated from the holo-ACP synthases of other enzyme systems. [Energy metabolism, Fermentation, Protein fate, Protein modification and repair].	5.54697e-86
CP027160.1\|AVK33920.1\|5107423_5108269_+\|arabinose-operon-regulatory-protein	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
CP027160.1\|AVK33300.1\|5091075_5091903_+\|dnaJ-like-protein-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	2.63694e-164
CP027160.1\|AVK34617.1\|5084949_5085309_-\|hypothetical-protein	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	8.5198e-73
CP027160.1\|AVK34802.1\|5087142_5088429_-\|chaperone-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0

>CP027160.1|AVK32736.1|5092623_5094249_-|sensor-histidine-kinase-CitA
MKLSFQYKLFISLVAFFSVLFIALGIYYYFDASRQLYQEMSARAKIQAEEIALMPNLRQQVSRHDPQAIQAFMQQIAAHSDASFIVIGDRQGVHLFHSVHPEWVGTRLVGGDNQAVLEGKSITTIRKGGLGVSLRSKTPIVDDAGRVIGIVSVGYLTSYLDSITLTKVINIFIAAVLLLIALFIFSWYFTRSIKKQIFSLEPREIGLLVRQQKAMMESIFEGVIVIDRQRRIEVINHAARSLLGLSQPARQLRGQSIDSVISPQPFFASGDMLERDTHDELCRFNQLTVLASRVRIMLENTLQGWVITFRDRNEINALTAQLSQVKRYVDNLRIMRHEQLNRMTTLSGLLHMGHYDEAIRYIQAQSEHAQELLDFISSHFHSPTLCGLLLGKATRAREKGVALSFDPACRIDRPLPSLMESELISIIGNLLDNAIEATQRAELPHEPVEVLIQLNARELIIEVADRGVGIRPDIRERIFERGVTTKTRGDHGIGLYLIEHYVTQAGGTIEVADNAPRGTIFTLFIPADAHACPQPEAHDAS
>CP027160.1|AVK33577.1|5091935_5092634_-|transcriptional-regulator-family-protein
MHHDLVDVLIIEDESELARLHAELVQKHPRLRLAGMAASLAQARQLLHATPPQLVLLDNYLPDGKGVTLMTDPALATSQCSVIFITAASDMETCSQAIRNGAFDYILKPVSWKRLSQSLERFIQFYDQQREWKIVDQQNVDSLYQLQAKNYRVDSGSKGIEEKTLALVQGLFSDREAHCFSVDEVVSAAGLSKTTARRYLEHGVETGFLEVEMLYGKIGHPRRLYRRAKVKS
>CP027160.1|AVK33300.1|5091075_5091903_+|dnaJ-like-protein-DjlA
MQYLGKVIGVAVALLMGGGFWGVVLGFLVGHMFDRARSRRLNLFANQQERQSLFFSTTFEVMGHLTKSKGRVTEADIHVANVLMDRMNLHGASRTAAQQAFRDGKADNYPLREKMRQLRSVCFGRFDLIRMFLEIQLQAAFADGELHPNEREVLFVIADELGISRAQFDQFLRMMQGGAQFGGGSQQRSYGQHGGNAGWQQAQRGPTLEDACNVLGVKPTDDAATVKRAYRKLMNEHHPDKLVAKGLPPEMMEMAKQKAQEIQKAWELIKEQRGF
>CP027160.1|AVK33284.1|5088483_5090832_-|LPS-assembly-protein-LptD
MKKRIPSLLATMIASALYSQQGLAADLATQCMLGVPSYDRPLVEGRPGDLPVTINADHAKGNYPDNAVFTGNVDINQGNSRLRADEVQLHQQQAAGQAQPVRTVDALGNVHYDDNQVILKGPKAWSNLNTKDTNVWQGDYQMVGRQGRGTADLMKQRGENRYTILENGSFTSCLPGSDTWSVVGSEVIHDREEQVAEIWNARFKLGSVPIFYSPYLQLPVGDKRRSGFLIPNAKYSTKNGVEFSLPYYWNIAPNFDATITPHYMNKRGGVMWENEFRYLTQLGSGLTEFDYLPSDKVYEDDHSSDSNSRRWLFYWNHSGVIDQVWRLNADYTKVSDPDYFNDFSSKYGSSTDGYATQKFSAGYVNQNFDATVSTKQFQVFDRESSNSYSAEPQLDVNYYQNDVGPFDTHLYGQVAHFVNSNNNMPEATRVHFEPTINLPLSNGWGSLNTEAKLLATHYQQSNLDKYNAANGTDYKESVSRVMPQFKVDGKMVFERDLQEGFTQTLEPRVQYLYVPYRDQSEIGNYDSTLLQSDYTGLFRDRTYSGLDRIASANQVTTGLTSRVYDAAAVERFNISVGQIYYFTESRTGDDNINWENNDTTGSLVWAGDTYWRIADEWGLRGGIQYDTRLDNVATGNGTIEYRRDENRLVQLNYRYASPEYIQATLPSYSTAAQYKQGISQVGMTASWPIVDRWSVVGAYYYDTNTRKAANQMLGVQYNSCCYAIRLGYERKVNGWNSNDNGGESKYDNTFGINIELRGLSSNYGLGTQQMLRSNILPYQSSL
>CP027160.1|AVK34802.1|5087142_5088429_-|chaperone-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAGQAGQQLPDDATLRHQILERLIMDQIVLQMGQKMGVKISDDQLDQAIANIAKQNNMTLDQMRSRLAYEGINYNTYRNQIRKEMLISEVRNNEVRRRITVLPQEVEALAKQIGDQNDASTELNLSHILIPLPENPTSDEVAAAQEQANSIVEQARNGANFGKLAITYSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGGTQNISVTEVHARHILLKPSPIMNDAQAQAKLEQIAAEIKSGKITFAQAAKTYSEDPGSANQGGDLGWATPDIFDPAFRDALMRLNKGQTSGPVHSSFGWHLIELLDSRQVDRTDAAQKDRAYRMLMNRKFSEEAATWMQEQRASAYVKILSN
>CP027160.1|AVK33836.1|5086147_5087137_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MPETRKVVITPGEPAGIGPDLVVQLAQRDWPVELVICADGALLTDRAKRLGLPLSLLPYDPAQPPVPQRAGTLTLLNVPLNVPAEPGVLNVQNGAYVVETLARACDGCLSGEFAALVTGPVHKGNINDAGIAFTGHTEFFEERAKASKVVMMLATEELRVALVTTHLPLKAISEAITPELLREIITILDHDLRTKFGIAQPHVLVCGLNPHAGEGGHMGTEEIDTIIPVLEEMRAKGMNLSGPLPADTLFQPKYLDHADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGQGKADVGSFITALNLAIKMIVNTQ
>CP027160.1|AVK34427.1|5085329_5086151_-|dimethyladenosine-transferase
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHSTMPYPVKEIRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTELGIDPAMRAENISVAQYCLMANWLSDNLPTKES
>CP027160.1|AVK34617.1|5084949_5085309_-|hypothetical-protein
MCVQVQSVYIESQSSPEEERYVFAYTVTIRNLGRSQVQLLGRYWLITNGHGRETEVQGEGVVGEQPHIPAGGEYQYTSGAVIETPLGTMQGHYEMIDIDGAPFRIEIPVFRLAVPTLIH
>CP027160.1|AVK31538.1|5084096_5084945_-|bis(5'-nucleosyl)-tetraphosphatase
MSTYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLKPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMPNHWSNELSGLARLRFISNAFTRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGIYALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS
>CP027160.1|AVK31316.1|5083361_5083841_+|dihydrofolate-reductase
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR
>CP027160.1|AVK31759.1|5094573_5095938_+|citrate/malate-transporter
MSTTDNAFSATLEPIDTPKTTLKQRWWHIMDNWKVGIVPLPLFLLAGGLIALDCLGGKLPSDIVVMVATLAFFGFACGEFGKRLPVLGKLGAAAICATFIPSALVHYGLLPDVVIESTTKFYKSTNILYLYICCIIVGSIMSMNRTTLIQGFLKIFFPMLCGEVVGMLVGIGVGTLLGMEPFQVFFFIVLPIMAGGVGEGAIPLSMGYAALMHMEQGVALGRVLPMVMLGSLTAIVISGCLNQLGKRFPHLTGEGQLMPNRSHETRSLSESEGVSGKTDVGTLASGALLAVLLYMMGMLGHKLIGLPAPVGMLFLAVLLKLANVVSPRLQEGSQMVYKFFRTAVTYPILFAVGVAITPWQELVNAFTLTNLLVIVSTVSALVATGFLVGKKIGMHPIDVAIVSCCQSGQGGTGDVAILTAGNRMSLMPFAQIATRIGGAINVSLGLLFLSHYLA
>CP027160.1|AVK30093.1|5096117_5096657_+|holo-ACP-synthase-CitX
MSVDTPAQAGVSIDALLAAKEQRAARQADWLAHYQQPVISLTLVTPGAVKDSIRYRNMMGVALQACDQLLWKHRWQTLDRQVLWLPTGPEALWCVAHPASEIKAMCSTLEQSHPLGRLWDIDVICPQNGLVGRQSLGESQRRCLLCDEPAHACARSRRHDTDLVVARVEQMIDAWFARD
>CP027160.1|AVK33180.1|5096731_5097391_-|pseudouridine-synthase,-RluA-family-protein
MAMENYNPPQDPWLVILYQDEHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDFPQAESVHRLDMATSGVIVVALNKAAERELKRQFREREPKKQYVARVWGHPQPAEGLVDLPLICDWPNRPKQKVCYETGKAAQTEYEVLEYAEDNTARVRLKPITGRSHQLRVHMLALGHPILGDRFYATPEALAMAPRLLLHAETLTITHPAYGNAMTFRAPIDF
>CP027160.1|AVK32361.1|5097403_5100247_-|RNA-polymerase-associated-protein-RapA
MVALDARMVTLLFPAIGENRLYSRNDSPITRVMFNPGDTITSHEGWQLHVDKVNEENGLLSYTGTRLDTQEANVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPWSGLRGQRTSLIPHQLHIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIVVPETLQHQWLVEMLRRFNLRFSLFDDERYAEAQHDAYNPFETEQLVICSLDFVRRSKQRLEHLCDAEWDLMVVDEAHHLVWSEEAPSREYQAIEQLAERVPGILLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQQNYRPVADAVALLLAGNKLSDSELNTLGDLIGEQDIEPLLQAANSDREDAQAARQELISMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIRLPLPTQYQTAIKVSGIMGARKTAEERARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTVYDSVHDELINYLAAPESIDGFDDLIKSCRQQHDALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTSLIAFSMNLFDIVGINQDDRGENLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLLELIYVVEAQAPKQLQLNRFLPATPVRMLLDKNGNNLAAQVEFESFNRQLSAVNRHTGSKLVNAVQQDVHAILQQGEAQIAKAAQGLIDAARNEADEKLTAELSRLEALKAVNPNIRDDELAGIESNRQQVMDALAQAGWRLDALRLIVVTHQ
>CP027160.1|AVK32023.1|5100497_5102855_-|DNA-polymerase-family-B,-exonuclease-domain-protein
MTQPRAGFLLTRHWRDTPQGTELSFWLATDDGPLQVTLPPQESVAFIPEAQRAQAERLLQGEKGLRFAPLALKDFHRQPIVGLYCRAHRQLMRLEKMLRDSGVTVYEGDIRPPERYLMERFITAPVWVEGETRGSQLVNARMKPNPDYRPPLKWVSLDIETSRHGELYCIGLEGCGQRVVYMLGPEPETPPDVDFELVFIASRPLLLEKLNAWFAEHDPDVLIGWNVVQFDLRVLQKHAERYRIPLRLGRGNSELEWREHGFKNGVFFAQANGRLIIDGIDALKSAFWNFSSFSLEAVARELLGEGKAIDNPWDRMDEIDRRFHEDKPALAIYNLQDCELVTRIFHKTEIMPFLLERATVNGLPADRHGGSVAAFSHLYFPRMHRLGYVAPNLGDVPPQASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLIEGLAQPDDQHSIEGFLGARFSRDKHCLPGIVSQIWHGRDEAKRQHNKPLSQALKIIMNAFYGVLGTSACRFFDPRLASSITMRGHAIMRQTKALIEAKGYDVIYGDTDSTFVWLKRPHSEAQAAEIGRELVSHVNAWWAQELSKSQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGMIQEGDAQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNQPYQDYVRETIARLMNGELDEQLVYRKRLRRPLAEYQRNVPPHVRAARLADEHNLKLGRAQQYQQRGTIKYVWTTSGPEPVDYQQSPLDYDHYLTKQLQPVAEGILPFVNDDFATIVTGQLGLF
>CP027160.1|AVK33132.1|5103030_5103726_-|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDREKGVFVIKPSGVDYRVMTADDMVVVSLESGEVVEGNKKPSSDTPTHRLLYQAFPTLGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGPVPCTRLMTDAEINGDYEWETGNVIVETFRQQGIDPAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEIAYMGIFCRQLAPQLPAMQQTLLDKHYLRKHGAKAYYGQ
>CP027160.1|AVK32612.1|5103863_5105366_-|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPEALRQVTKHAEHVVNSLNAEAKLPCKLVLKPLGTTPDEITHICRDANYDDKCAGLVVWLHTFSPAKMWINGLTILNKPLLQFHTQYNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHSVVTGHWQDKEAHQRIGGWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDISALVDEYESSYRLTPAAQVHGEKRQNVLDAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFDNGNDLVLGSHMLEVCPTIATVEKPILDVQPLGIGGKADPARLIFNTQTGPAIVASLIDLGDRFRLLVNTIETVPTPHDLPKLPVANALWKAQPDLRTASEAWIIAGGAHHTVFSHALNLDDMRQFAELHDIELTVIDNDTRLPSFKDALRWNEVYYGSKR
>CP027160.1|AVK34758.1|5105376_5107086_-|L-ribulokinase
MAIAIGLDFGSDSVRALAVECASGAELATSVEWYPRWREGQYCDGANNRFRHHPRDYIESMEAALKSVLASLSAEQRADVVGIGVDSTGSTPAPVDAEGNVLALREEFADNPNAMFVLWKDHTAVEEAEAITRLCHQPGKEDYSRYIGGIYSSEWFWAKILHVTREDSAVAQAAASWVELCDWVPALLSGTTRPQDLRRGRCSAGHKSLWHESWGGLPPASFFDELDPIINQHLAWPLFTDTWTADVPVGTLSAEWAQRLGLSQSVAISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKESVGERTVKGICGQVDGSVVPHFIGMEAGQSAFGDIYAWFGRILGWPLEQLAQQQPALREQIKASQKQLLPALTEAWANNPSLEHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLIAATAFGARAIMECFTEQGIPVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAGVYDDIPAAQQRMASQVETTLQPRPAQAQRFEQLYQRYQQWSVSAEQHYLPSAAKAEKAPQSKAALTH
>CP027160.1|AVK29969.1|5107267_5107438_-|hypothetical-protein
MRFGHTRGSPRRYQWHQLSIFIILSLSALSRLRRRWEFGEKPAQQAKKAPAACIPP
>CP027160.1|AVK33920.1|5107423_5108269_+|arabinose-operon-regulatory-protein
MAETQNDPLLPGYSFNAHLVTGLTPIEAQGYLDFFIDRPLGMKGYILNLTIRGEGVINNHGEQFVCRPGDMLLFPPGEIHHYGRHPDASEWYHQWVYFRPRAYWHEWLNWPTIFAQTGFFRPDEQWQARFGELFGQIVDAGQGAGRYSELLAINLLEQLLLRRMEAINESLHPPLDNRVREACQYISDHLADSHFDIASVAQHVCLSPSRLSHLFRQQLGVSVLGWREDQRISQAKLLLSTTRMPIATVGRNVGFEDQLYFSRVFKKCTGASPSEFRAGCE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

151707 : 163361

Enterobacteria_phage(70.0%)

capsid,integrase

attL 139841:139855|attR 162898:162912

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
139841:139855	attL	NA	NA	NA	NA
AVK34233.1\|151707_154041_-	putative P4-specific DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	82.2
AVK34647.1\|154052_154373_-	putative dNA replication protein	NA	NA	NA	NA
AVK30892.1\|154369_154549_-	hypothetical protein	NA	NA	NA	NA
AVK34321.1\|154593_154788_-	putative phage immunity repressor protein	Q7M2A7	Enterobacteria_phage	3.2e-22	85.5
AVK31805.1\|155147_155414_-	prophage CP4-57 regulatory family protein	Q7M299	Enterobacteria_phage	2.6e-30	71.6
AVK34166.1\|155518_155656_+	hypothetical protein	NA	NA	NA	NA
AVK33926.1\|155955_156693_+\|capsid	putative glyco3, capsid size determination protein Sid	Q7M2A2	Enterobacteria_phage	9.0e-73	60.7
AVK33096.1\|156689_156935_+	ogr/Delta-like zinc finger family protein	Q7M294	Enterobacteria_phage	1.9e-19	58.0
AVK32338.1\|156952_157519_+	polarity suppression protein	Q7M2A1	Enterobacteria_phage	1.5e-59	64.3
AVK33330.1\|158087_158513_-	hypothetical protein	NA	NA	NA	NA
AVK32467.1\|158512_159445_-	cobQ/CobB/MinD/ParA nucleotide binding domain protein	Q8JL10	Natrialba_phage	1.5e-08	25.3
AVK33948.1\|159450_160641_-\|integrase	phage integrase family protein	Q7M297	Enterobacteria_phage	6.4e-145	62.7
AVK31968.1\|160993_162247_-	gamma-glutamyl phosphate reductase	A0A1X9I5D4	Streptococcus_phage	8.9e-89	44.9
AVK34342.1\|162257_163361_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.8e-62	40.5
162898:162912	attR	NA	NA	NA	NA

DBSCAN-SWA_2

814167 : 851503

Salmonella_phage(87.5%)

head,plate,integrase,capsid,tail,lysis,portal,terminase

attL 814075:814093|attR 851575:851593

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
814075:814093	attL	NA	NA	NA	NA
AVK33978.1\|814167_815148_-\|integrase	phage integrase family protein	A0A218M4I3	Erwinia_phage	1.4e-97	57.2
AVK29971.1\|815638_817123_+	reverse transcriptase family protein	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
AVK31160.1\|817221_818166_-	hypothetical protein	NA	NA	NA	NA
AVK33737.1\|818177_819113_-	bacteriophage CI repressor helix-turn-helix domain protein	A0A1S6KZZ7	Salmonella_phage	1.8e-30	39.9
AVK34015.1\|819276_819429_-	hypothetical protein	NA	NA	NA	NA
AVK33557.1\|819455_819965_+	phage regulatory CII family protein	E5G6L3	Salmonella_phage	5.8e-87	98.8
AVK31771.1\|819972_820173_+	protein fil	E5G6L4	Salmonella_phage	1.6e-32	97.0
AVK33472.1\|820247_820364_-	hypothetical protein	NA	NA	NA	NA
AVK34901.1\|820337_820478_+	putative fels-2 prophage protein	E5G6L5	Salmonella_phage	3.5e-18	100.0
AVK30653.1\|820545_820779_+	hypothetical protein	E5G6L6	Salmonella_phage	4.1e-32	96.1
AVK32862.1\|820778_821006_+	phage/conjugal plasmid C-4 type zinc finger, TraR family protein	E5G6L7	Salmonella_phage	6.0e-36	98.7
AVK34186.1\|821002_821860_+	DNA adenine methylase family protein	E5G6L8	Salmonella_phage	2.0e-156	95.4
AVK34031.1\|821856_824271_+	bacteriophage replication protein A	E5G6L9	Salmonella_phage	0.0e+00	97.5
AVK33148.1\|824424_824613_+	putative levan regulatory protein	E5G6M0	Salmonella_phage	5.5e-27	98.4
AVK33515.1\|824623_824857_+	dinI-like family protein	E5G6M1	Salmonella_phage	4.7e-36	100.0
AVK33613.1\|825460_825649_+	putative fels-2 prophage protein	NA	NA	NA	NA
AVK34288.1\|825924_827667_+	AIPR family protein	NA	NA	NA	NA
AVK32559.1\|827728_828754_-\|portal	phage portal protein, PBSX family	A0A1S6KZW5	Salmonella_phage	7.6e-171	86.7
AVK31722.1\|828753_830520_-	sigma-70, region 4 family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	99.0
AVK30530.1\|830662_831496_+\|capsid	phage capsid scaffolding (GPO) serine peptidase family protein	A0A1S6KZW9	Salmonella_phage	6.3e-123	88.8
AVK31631.1\|831512_832571_+\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	1.1e-180	93.1
AVK33750.1\|832574_833225_+\|terminase	phage small terminase subunit	E5G6M7	Salmonella_phage	8.7e-112	96.3
AVK30166.1\|833320_833785_+\|head	phage head completion family protein	A0A1S6KZW8	Salmonella_phage	8.4e-77	89.0
AVK33922.1\|833784_833988_+	phage Tail Protein X family protein	A0A1S6KZY4	Salmonella_phage	1.3e-29	88.1
AVK33061.1\|833991_834207_+	putative membrane protein	E5G6N0	Salmonella_phage	3.6e-30	90.1
AVK32593.1\|834187_834697_+	phage lysozyme family protein	E5G6N1	Salmonella_phage	2.1e-81	83.4
AVK30780.1\|834701_835085_+	putative membrane protein	A0A1S6KZZ2	Salmonella_phage	2.1e-17	42.0
AVK31562.1\|835081_835510_+\|lysis	phage lysis regulatory, LysB family protein	A0A1S6KZX8	Salmonella_phage	9.6e-51	77.9
AVK29990.1\|835496_835643_+	hypothetical protein	A0A1S6KZX6	Salmonella_phage	6.0e-13	76.1
AVK33440.1\|835605_836037_+\|tail	P2 phage tail completion R family protein	A0A1S6KZY0	Salmonella_phage	9.9e-64	82.5
AVK31998.1\|836071_836476_+	phage virion morphogenesis protein	E5G6N4	Salmonella_phage	4.3e-45	72.0
AVK32606.1\|836472_836982_-	hypothetical protein	NA	NA	NA	NA
AVK30931.1\|836980_837145_+	hypothetical protein	NA	NA	NA	NA
AVK32052.1\|837259_837832_+\|plate	phage baseplate assembly V family protein	E5G6N6	Salmonella_phage	4.7e-77	72.3
AVK32579.1\|837846_838191_+	lysozyme family protein	A0A1S6KZZ4	Salmonella_phage	3.7e-45	83.9
AVK31669.1\|838177_839086_+\|plate	baseplate J-like family protein	E5G6N8	Salmonella_phage	7.6e-106	66.9
AVK34082.1\|839078_839678_+\|tail	phage tail protein I	A0A1S6L000	Salmonella_phage	1.3e-58	60.5
AVK34734.1\|839667_842631_+	hypothetical protein	A0A2H4N7A3	Pectobacterium_phage	1.2e-06	50.9
AVK31236.1\|842634_843366_+	concanavalin A-like lectin/glucanases superfamily protein	NA	NA	NA	NA
AVK33693.1\|843404_843566_+	hypothetical protein	NA	NA	NA	NA
AVK31664.1\|843595_844672_+\|tail	phage tail-collar fiber family protein	Q37842	Escherichia_phage	1.2e-25	44.8
AVK31659.1\|844810_845983_+\|tail	phage tail sheath family protein	A0A1S6KZY7	Salmonella_phage	1.9e-210	93.3
AVK30916.1\|845992_846508_+\|tail	phage major tail tube protein	E5G6P8	Salmonella_phage	1.3e-81	85.4
AVK33189.1\|846560_846860_+	mu-like prophage FluMu gp41 family protein	E5G6P9	Salmonella_phage	3.7e-33	79.0
AVK34743.1\|846874_846994_+	phage P2 GpE family protein	E5G6Q0	Salmonella_phage	2.2e-13	87.2
AVK32930.1\|846986_849614_+\|tail	phage tail tape measure protein, TP901 family, core region	E5FFG5	Burkholderia_phage	5.6e-117	42.0
AVK30390.1\|849610_850096_+	phage P2 GpU family protein	E5G6Q2	Salmonella_phage	7.2e-63	75.6
AVK32443.1\|850092_851193_+	phage late control D family protein	A0A1S6KZZ5	Salmonella_phage	4.9e-176	87.4
AVK31823.1\|851347_851503_+	ogr/Delta-like zinc finger family protein	E5G6Q4	Salmonella_phage	3.8e-10	65.3
851575:851593	attR	NA	NA	NA	NA

DBSCAN-SWA_3

885919 : 895383

Dickeya_phage(16.67%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVK31194.1\|885919_887035_+	macrolide-specific efflux protein MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7
AVK31204.1\|887031_888972_+	macrolide export ATP-binding/permease protein MacB	G9BWD6	Planktothrix_phage	1.9e-37	40.5
AVK32057.1\|889048_889270_-	cold shock domain protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
AVK32501.1\|889595_889913_+\|protease	ATP-dependent Clp protease adaptor ClpS family protein	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
AVK30759.1\|889943_892223_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.6e-165	42.0
AVK30258.1\|892343_892562_-	translation initiation factor IF-1	NA	NA	NA	NA
AVK32885.1\|892915_893617_-\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
AVK32833.1\|893661_895383_-	thiol reductant ABC exporter, CydC subunit	A0A2R8FG22	Brazilian_cedratvirus	1.5e-14	34.3

DBSCAN-SWA_4

1544304 : 1555191

Escherichia_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVK33247.1\|1544304_1544898_-	class II Aldolase and Adducin N-terminal domain protein	A0A077SK32	Escherichia_phage	9.6e-110	100.0
AVK33936.1\|1544917_1546183_-	hypothetical protein	A0A077SLJ7	Escherichia_phage	6.6e-233	99.5
AVK32479.1\|1546194_1547097_-	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain protein	A0A077SLF7	Escherichia_phage	7.7e-159	99.3
AVK30739.1\|1547357_1548119_+	HTH domain protein	A0A077SK06	Escherichia_phage	1.9e-134	100.0
AVK31297.1\|1548139_1549000_-	beta-lactamase SHV-1	A0A077SL40	Escherichia_phage	2.2e-155	99.3
AVK32561.1\|1549318_1549558_+	hypothetical protein	A0A077SK33	Escherichia_phage	6.3e-36	97.5
AVK33008.1\|1549644_1550733_+	recF/RecN/SMC N terminal domain protein	A0A077SLJ9	Escherichia_phage	8.0e-211	100.0
AVK31750.1\|1550763_1552029_-	lactose permease	NA	NA	NA	NA
AVK30080.1\|1552083_1555191_-	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	59.6

DBSCAN-SWA_5

2554473 : 2561359

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVK30104.1\|2554473_2555952_+	signal transduction histidine-protein kinase BaeS	W8CYF6	Bacillus_phage	1.1e-29	28.3
AVK33947.1\|2555948_2556671_+	transcriptional regulatory, C terminal family protein	W8CYM9	Bacillus_phage	6.4e-31	33.2
AVK34585.1\|2556989_2558351_+	peptidase U32 family protein	Q6DW11	Phage_TP	2.5e-206	94.5
AVK31780.1\|2558596_2559490_+	lipid kinase YegS	A0A1V0SBJ0	Catovirus	6.1e-15	29.8
AVK32733.1\|2559490_2559622_-	hypothetical protein	NA	NA	NA	NA
AVK30747.1\|2559732_2560506_-	ABC transporter family protein	G9BWD6	Planktothrix_phage	1.5e-25	36.3
AVK30180.1\|2560516_2561359_-	ABC transporter family protein	G9BWD6	Planktothrix_phage	5.5e-10	27.5

DBSCAN-SWA_6

3735619 : 3780004

uncultured_Caudovirales_phage(66.67%)

head,capsid,tail,protease,portal,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVK33624.1\|3735619_3736987_+\|protease	periplasmic pH-dependent serine endoprotease DegQ	A0A1B1IT49	uncultured_Mediterranean_phage	6.0e-22	25.3
AVK30724.1\|3737074_3738133_+	periplasmic serine peptidase DegS	NA	NA	NA	NA
AVK30349.1\|3738269_3739208_-	malate dehydrogenase, NAD-dependent	NA	NA	NA	NA
AVK31938.1\|3739622_3740093_+	arginine repressor	NA	NA	NA	NA
AVK33193.1\|3740468_3740732_+	hypothetical protein	NA	NA	NA	NA
AVK34747.1\|3740980_3741097_+	hypothetical protein	NA	NA	NA	NA
AVK34822.1\|3741147_3741423_-	hypothetical protein	NA	NA	NA	NA
AVK31957.1\|3741502_3743470_-	p-hydroxybenzoic acid efflux pump subunit AaeB	NA	NA	NA	NA
AVK33080.1\|3743475_3744366_-	efflux transporter, RND family, MFP subunit	NA	NA	NA	NA
AVK30314.1\|3744415_3744619_-	hypothetical protein	NA	NA	NA	NA
AVK33387.1\|3744750_3745680_+	lysR substrate binding domain protein	NA	NA	NA	NA
AVK32266.1\|3745715_3747161_-	modulator of DNA gyrase family protein	NA	NA	NA	NA
AVK34366.1\|3747249_3751014_-	asmA-like C-terminal region family protein	NA	NA	NA	NA
AVK33760.1\|3751084_3752554_-	ribonuclease, Rne/Rng family domain protein	NA	NA	NA	NA
AVK30586.1\|3752556_3753138_-	septum formation protein Maf	NA	NA	NA	NA
AVK34108.1\|3753145_3753634_-	rod shape-determining protein MreD	NA	NA	NA	NA
AVK32505.1\|3753633_3754626_-	rod shape-determining protein MreC	NA	NA	NA	NA
AVK31086.1\|3754696_3755740_-	rod shape-determining protein MreB	F2Y0P3	Organic_Lake_phycodnavirus	6.7e-05	22.3
AVK33617.1\|3756045_3757986_-	RNase E specificity factor CsrD	NA	NA	NA	NA
AVK34773.1\|3758065_3758257_-	hypothetical protein	NA	NA	NA	NA
AVK34670.1\|3758485_3759487_+	sulfoxide reductase catalytic subunit YedY	NA	NA	NA	NA
AVK34066.1\|3759486_3760095_+	ferric reductase like transmembrane component family protein	NA	NA	NA	NA
AVK31499.1\|3760318_3760771_+	3-dehydroquinate dehydratase, type II	NA	NA	NA	NA
AVK33542.1\|3760793_3761261_+	acetyl-CoA carboxylase, biotin carboxyl carrier protein	NA	NA	NA	NA
AVK34240.1\|3761271_3762621_+	acetyl-CoA carboxylase, biotin carboxylase subunit	NA	NA	NA	NA
AVK34264.1\|3762731_3762974_+	hypothetical protein	NA	NA	NA	NA
AVK34004.1\|3762963_3764415_+	sodium/pantothenate symporter	NA	NA	NA	NA
AVK30954.1\|3764426_3765308_+	ribosomal protein L11 methyltransferase	NA	NA	NA	NA
AVK30369.1\|3765785_3766631_+	TIM-barrel, nifR3 family protein	NA	NA	NA	NA
AVK33974.1\|3766655_3766952_+	bacterial regulatory, Fis family protein	NA	NA	NA	NA
AVK30738.1\|3767105_3767297_-	hypothetical protein	NA	NA	NA	NA
AVK34079.1\|3767299_3768961_-	phage Terminase family protein	A0A2H4JB64	uncultured_Caudovirales_phage	0.0e+00	98.0
AVK32357.1\|3768944_3769301_-\|terminase	phage terminase, small subunit, P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	5.5e-60	99.2
AVK33882.1\|3769431_3769584_-	hypothetical protein	A0A2H4JCY9	uncultured_Caudovirales_phage	2.4e-17	88.0
AVK31040.1\|3769576_3769969_-	HNH endonuclease family protein	A0A2H4JAS8	uncultured_Caudovirales_phage	1.4e-64	90.0
AVK32206.1\|3770019_3770136_-	putative hNH endonuclease	A0A2H4JD08	uncultured_Caudovirales_phage	1.4e-12	89.5
AVK33028.1\|3770315_3770471_-\|head,tail	phage head-tail joining family protein	A0A1P8DTK6	Proteus_phage	7.2e-09	54.0
AVK31660.1\|3770647_3771889_-\|portal	phage portal protein, HK97 family	A0A2H4JFJ9	uncultured_Caudovirales_phage	1.0e-230	96.5
AVK30590.1\|3771890_3772451_-\|head,protease	phage prohead protease, HK97 family	A0A2H4JB68	uncultured_Caudovirales_phage	1.2e-98	95.7
AVK33982.1\|3772502_3773669_-\|capsid	phage major capsid protein, HK97 family	A0A2H4JED2	uncultured_Caudovirales_phage	9.8e-207	95.9
AVK31213.1\|3773932_3774445_+	hypothetical protein	NA	NA	NA	NA
AVK30710.1\|3774493_3774829_-	hypothetical protein	NA	NA	NA	NA
AVK33229.1\|3775171_3777301_-	hypothetical protein	A0A1W6JPG0	Morganella_phage	3.4e-205	62.4
AVK34197.1\|3777306_3777672_-	hypothetical protein	NA	NA	NA	NA
AVK29970.1\|3777668_3778025_-	hypothetical protein	A0A2H4JCX7	uncultured_Caudovirales_phage	2.3e-50	81.4
AVK33709.1\|3778033_3778348_-	hypothetical protein	NA	NA	NA	NA
AVK30236.1\|3778340_3778529_-	hypothetical protein	NA	NA	NA	NA
AVK32936.1\|3778521_3778701_-	hypothetical protein	A0A2H4JGW3	uncultured_Caudovirales_phage	2.6e-26	94.9
AVK32121.1\|3779242_3780004_-	phage antirepressor KilAC domain protein	Q8HA02	Enterobacteria_phage	6.1e-40	51.5

DBSCAN-SWA_7

4671831 : 4676918

Escherichia_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVK32532.1\|4671831_4672788_+	plasmid segregation protein ParM	A0A222YXF2	Escherichia_phage	1.3e-143	78.0
AVK33140.1\|4672797_4673169_+	plasmid stability family protein	A0A222YWJ6	Escherichia_phage	2.8e-22	53.7
AVK30824.1\|4673334_4674120_-	DDE domain protein	A0A2I6AZV9	Macacine_betaherpesvirus	3.3e-73	67.7
AVK31946.1\|4674176_4674698_-\|transposase	transposase family protein	A0A1B1P776	Bacillus_phage	1.3e-14	33.5
AVK33479.1\|4674866_4675172_-	chaperone modulatory protein CbpM	NA	NA	NA	NA
AVK33375.1\|4675171_4676089_-	curved DNA-binding protein	A0A1V0SCV5	Indivirus	2.8e-07	42.2
AVK31403.1\|4676164_4676278_+	hypothetical protein	NA	NA	NA	NA
AVK30122.1\|4676234_4676918_-	integral membrane, YjbE family protein	W8EBD0	Pseudomonas_phage	5.1e-30	42.2

DBSCAN-SWA_8

4872056 : 4879738

Enterobacteria_phage(85.71%)

integrase,capsid,transposase

attL 4865658:4865672|attR 4886607:4886621

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4865658:4865672	attL	NA	NA	NA	NA
AVK33745.1\|4872056_4872623_-	polarity suppression protein	Q7M2A1	Enterobacteria_phage	9.7e-59	63.8
AVK31479.1\|4872640_4872886_-	ogr/Delta-like zinc finger family protein	Q7M294	Enterobacteria_phage	5.5e-19	56.8
AVK34838.1\|4872882_4873620_-\|capsid	putative glyco3, capsid size determination protein Sid	Q7M2A2	Enterobacteria_phage	1.1e-70	59.4
AVK31693.1\|4874180_4874447_+	prophage CP4-57 regulatory family protein	Q7M299	Enterobacteria_phage	2.0e-30	71.6
AVK31944.1\|4874797_4874992_+	putative phage immunity repressor protein	Q7M2A7	Enterobacteria_phage	7.2e-22	85.5
AVK33724.1\|4874988_4875216_+	hypothetical protein	NA	NA	NA	NA
AVK31380.1\|4875263_4875533_+	DNA replication protein, phage-associated	NA	NA	NA	NA
AVK31754.1\|4875547_4877881_+	zinc-binding domain of primase-helicase family protein	Q7M2A8	Enterobacteria_phage	0.0e+00	83.9
AVK33924.1\|4877913_4878030_+	hypothetical protein	NA	NA	NA	NA
AVK31699.1\|4878626_4878893_+\|transposase	transposase family protein	NA	NA	NA	NA
AVK34687.1\|4878970_4879126_-	hypothetical protein	NA	NA	NA	NA
AVK34349.1\|4879258_4879738_+\|integrase	integrase core domain protein	A0A0N9SIX5	Staphylococcus_phage	1.6e-06	29.7
4886607:4886621	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage