CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP027776	Clostridium botulinum strain Mfbjulcb5 chromosome, complete genome	1 crisprs	csa3,WYL,DEDDh,RT,cas3,DinG	0	2	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP027776_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP027776_2

2662736-2662906

Orphan

Consensus_repeat	Method
TTTTGTACTTTTTGTACATATAATTAAGGACTAT	PILER-CR

2 spacers

The CRISPR arrays of CP027776_2

>merge|CP027776|2|2662736-2662906|PILER-CR
ATATAATTAAGGACTATAGTTTTTTCCATTTATTATCAATAAACAAAAAAACACCTTATTTAAGGTGCTTTTGTACTTTTTGTACATATTTTTTATATTTAATTTGATTTTTGAAATAAATAAACTGTAAAAAGTATTTTTGTACTTTTTGTATATATAATTAAGTACTAT

>CP027776|2|1|2662736-2662906|PILER-CR
ATATAATTAAGGACTATAGTTTTTTCCATTTATT	ATCAATAAACAAAAAAACACCTTATTTAAGGTGCTTTTGTACTTTTTGTAC
ATATTTTTTATATTTAATTTGATTTTTGAAATAA	ATAAACTGTAAAAAGTATTTTTGTACTTTTTGTATATATAATTAAGTA
CTAT

Protein	Signature genes	Signature genes Name	Protein_function
CP027776.1\|AVP65071.1\|2668960_2669647_-\|VanZ-family-protein	unknown	unknown	gnl\|CDD\|377417
CP027776.1\|AVP65072.1\|2669791_2670868_-\|ABC-transporter-permease	unknown	unknown	unknown
CP027776.1\|AVP65058.1\|2652991_2654164_+\|potassium-transporter	unknown	unknown	gnl\|CDD\|366411
CP027776.1\|AVP65063.1\|2657626_2658916_-\|DUF5050-domain-containing-protein	unknown	unknown	gnl\|CDD\|379846
CP027776.1\|AVP65060.1\|2654789_2655026_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379655
CP027776.1\|AVP65057.1\|2652421_2652799_-\|hypothetical-protein	unknown	unknown	unknown
CP027776.1\|AVP65061.1\|2655045_2655939_+\|polysaccharide-deacetylase	unknown	unknown	gnl\|CDD\|200569
CP027776.1\|AVP65065.1\|2660289_2660706_-\|flavodoxin	unknown	unknown	gnl\|CDD\|235508
CP027776.1\|AVP65075.1\|2672300_2672816_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377417
CP027776.1\|AVP65069.1\|2667280_2667985_-\|aquaporin-family-protein	unknown	unknown	gnl\|CDD\|223653
CP027776.1\|AVP65073.1\|2670851_2671748_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
CP027776.1\|AVP65066.1\|2660972_2662394_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240548
CP027776.1\|AVP65068.1\|2665493_2666990_-\|glycerol-kinase	unknown	unknown	gnl\|CDD\|234594
CP027776.1\|AVP65074.1\|2671753_2672134_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639
CP027776.1\|AVP65076.1\|2673246_2674959_+\|hydroxylamine-reductase	unknown	unknown	gnl\|CDD\|235391
CP027776.1\|AVP65070.1\|2668526_2668847_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376657
CP027776.1\|AVP65059.1\|2654176_2654527_+\|hypothetical-protein	unknown	unknown	unknown
CP027776.1\|AVP65067.1\|2663032_2665099_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
CP027776.1\|AVP65064.1\|2658953_2659934_-\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|224012
CP027776.1\|AVP65062.1\|2655960_2657334_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240539

Protein	Function_ID	Function_description	E-value
CP027776.1\|AVP65071.1\|2668960_2669647_-\|VanZ-family-protein	gnl\|CDD\|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	2.37442e-18
CP027776.1\|AVP65074.1\|2671753_2672134_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	1.90652e-42
CP027776.1\|AVP65058.1\|2652991_2654164_+\|potassium-transporter	gnl\|CDD\|366411	pfam00999, Na_H_Exchanger, Sodium/hydrogen exchanger family. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.	1.80328e-21
CP027776.1\|AVP65063.1\|2657626_2658916_-\|DUF5050-domain-containing-protein	gnl\|CDD\|379846	pfam16472, DUF5050, Domain of unknown function (DUF5050).	2.96251e-40
CP027776.1\|AVP65060.1\|2654789_2655026_+\|hypothetical-protein	gnl\|CDD\|379655	pfam14584, DUF4446, Protein of unknown function (DUF4446). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 165 and 176 amino acids in length.	0.00542165
CP027776.1\|AVP65061.1\|2655045_2655939_+\|polysaccharide-deacetylase	gnl\|CDD\|200569	cd10944, CE4_SmPgdA_like, Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins. This family is represented by a putative polysaccharide deacetylase PgdA from the oral pathogen Streptococcus mutans (SmPgdA) and Bacillus subtilis YheN (BsYheN), which are members of the carbohydrate esterase 4 (CE4) superfamily. SmPgdA is an extracellular metal-dependent polysaccharide deacetylase with a typical CE4 fold, with metal bound to a His-His-Asp triad. It possesses de-N-acetylase activity toward a hexamer of chitooligosaccharide N-acetylglucosamine, but not shorter chitooligosaccharides or a synthetic peptidoglycan tetrasaccharide. SmPgdA plays a role in tuning cell surface properties and in interactions with (salivary) agglutinin, an essential component of the innate immune system, most likely through deacetylation of an as-yet-unidentified polysaccharide. SmPgdA shows significant homology to the catalytic domains of peptidoglycan deacetylases from Streptococcus pneumoniae (SpPgdA) and Listeria monocytogenes (LmPgdA), both of which are involved in the bacterial defense mechanism against human mucosal lysozyme. The Bacillus subtilis genome contains six polysaccharide deacetylase gene homologs: pdaA, pdaB (previously known as ybaN), yheN, yjeA, yxkH and ylxY. The biological function of BsYheN is still unknown. This family also includes many uncharacterized polysaccharide deacetylases mainly found in bacteria.	5.77933e-82
CP027776.1\|AVP65065.1\|2660289_2660706_-\|flavodoxin	gnl\|CDD\|235508	PRK05568, PRK05568, flavodoxin; Provisional.	2.73463e-67
CP027776.1\|AVP65075.1\|2672300_2672816_-\|hypothetical-protein	gnl\|CDD\|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	3.36239e-18
CP027776.1\|AVP65069.1\|2667280_2667985_-\|aquaporin-family-protein	gnl\|CDD\|223653	COG0580, GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism].	2.16719e-75
CP027776.1\|AVP65073.1\|2670851_2671748_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.06992e-72
CP027776.1\|AVP65066.1\|2660972_2662394_-\|MATE-family-efflux-transporter	gnl\|CDD\|240548	cd13143, MATE_MepA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.	6.71787e-101
CP027776.1\|AVP65068.1\|2665493_2666990_-\|glycerol-kinase	gnl\|CDD\|234594	PRK00047, glpK, glycerol kinase GlpK.	0
CP027776.1\|AVP65070.1\|2668526_2668847_+\|hypothetical-protein	gnl\|CDD\|376657	pfam01906, YbjQ_1, Putative heavy-metal-binding. From comparative structural analysis, this family is likely to be a heavy-metal binding domain. The domain oligomerizes as a pentamer. The domain is about 100 amino acids long and is found in prokaryotes.	8.49941e-46
CP027776.1\|AVP65076.1\|2673246_2674959_+\|hydroxylamine-reductase	gnl\|CDD\|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0
CP027776.1\|AVP65067.1\|2663032_2665099_-\|cupin-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.03083e-24
CP027776.1\|AVP65064.1\|2658953_2659934_-\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|224012	COG1087, GalE, UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane].	0
CP027776.1\|AVP65062.1\|2655960_2657334_-\|MATE-family-efflux-transporter	gnl\|CDD\|240539	cd13134, MATE_like_8, Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	3.20278e-130

>CP027776.1|AVP65066.1|2660972_2662394_-|MATE-family-efflux-transporter
MGIDYKLFSKEKVEKALLKFAVPAMISLLVMELYNMVDTFFVGLAIGPKAIGALTIAFPVQRLMSSLGMMIAVGASTAVARSLGKKDYDNLKSVILNAINITIVIMVVLTLIISIFKKDMITGLLGASQSIYPYAEKYISIVVLGGLFQALTLVICYIMTSLGYTNITLKATSVGAILNVIIDYFLVMHLNFGVAGAAIATVVSQTVALVYAIYKLNKVKKKIGLNLKLNFELKLDILKPILAVGFSTFIIEISDAVVAVILNNILSIYGGDKALIIVGVTTKISMFLFITVIGISSAMQPIAAFNYGAKDLVRVKEVVVKTIVAVTGATLILWAVMLIFANPIIGLFLKDTSLLVETVKAFRIIISLFPTIGIYYVSIYYYQSMGKARTSLILSVYRQMIIFIPLLFILVGKFNIMGAWIAYPISDLISAITGVIYVRVALKEKDKAIEAQQYEKERKEKAFKGRSVKVGGL
>CP027776.1|AVP65065.1|2660289_2660706_-|flavodoxin
MAKVNIIYWSGTGNTEKMAEAIKEGLASAEVKLLSVSDATTKDVEEAEVVVLGCPSMGDEVLEEGEMEPFVDSISNIVKGKKVALFGSYGWGDGQWMRDWEERMESYGAEIKAESLIHQGEPDDSTIEECKAFAQRLV
>CP027776.1|AVP65064.1|2658953_2659934_-|UDP-glucose-4-epimerase-GalE
MAVLVCGGAGYIGSHAVAGLIEKNEEVVIVDNLVTGHEQAICGGKFYKGDLRDKEFLNKVFVQNKIDEVIHFAAFSLVGESMEEPFKYYNNNVCGTLSLLETMKEHNVHKIVFSSTAATYGEPENIPILEENLTGPTNAYGETKLAVEKMLKWAEIAYNIKYVVLRYFNVAGAHESGNIGEAHKVESHLIPIILQVALGRREKIMIYGDDYNTKDGSCVRDYIHVMDLVEAHIIALEKLRRDNTSATYNLGNGEGFSVKEVIEICRKVTGHIIPSEIAARRSGDPAILIASSEKIMKELGWKPKKASLESIIHSAWNWHKSHPNGY
>CP027776.1|AVP65063.1|2657626_2658916_-|DUF5050-domain-containing-protein
MEDKFVDLNLKFNEEIDEKSIHSNILVVKDTRGNIVTSHIKVEQKNILNIKIKADEEYIDNEYMLEFKDCIYSKNGNAFKELDNIKFCLNKGKIENNGTRVVKEDNWIYYSGNEKIYTYMDYNPHGEIRKVNLDGSLNIKLCDDFASNIWINGQWVYYVNHKGGNEENCLYRIKKDGSSRERLTNTTIDSLVFSDNYIFYSEYISSSSKDNYKIYRIKKDGSNKIALSNVRGTNLIIQGPFLYYLNIEDNYSIYRIRVDGLDMKKINNYSSRNFMKIQDGWIYYINEELGNNLYRITLDGNYEERLNNDSCINAVMDNRRIYYGKDIDSEKTYLYRINIDGLERKKICEGDCSRAIVLTRDNIYFSGNSKEGIYKIRKEGGELCTITKDNVLGLDIVGHWIYYYKLNLEELSMKLHRINLYLNKKQEVL
>CP027776.1|AVP65062.1|2655960_2657334_-|MATE-family-efflux-transporter
MVNSKNLCKDLFNDKMFYSKLFKIALPVVIQNFIASSLNMVDTMMIGKVGEAEIAAVGIANQYFLLFSLFIIGFASGCSIFISQFWGKKDKKNIKKILGMGLIISTIIAILFTAMALIMPDKIILFYNKDSNVVSLGSDYLVIVSISYIFTAITFNYGIGLRCIEKATVPMLISMVALLVNTILNYTLIFGHFGFEAMGVKGAAIATLIARIIESVVTIIYVYHRKTVLAATPKEMISVDKEFFTKSIKTIIPVVLNEVCWGLGMTVYSAVYGRIGTKAIASVQICTTVQNLFMVISFGLANASTVMIGHEIGASKEENGKLYAKRFAILGVIAGLILGIIIALSANAILSIFSVSEEVIQDSLKILYITALVMVVRVFNITLIVGILRGGGDAKTPLLIEAFTMWCIGVPLALLGAFVLKLPVYWVVALSTAEELSKFVIGLKRLKSNKWIRNVTV
>CP027776.1|AVP65061.1|2655045_2655939_+|polysaccharide-deacetylase
MRNSRKNIYSKKRHHDLRNTVTICLLFFSIISTFITGGRLLKVKIQNNMLGKKITNMSSENKNIKNENIKLMSDIDKENETYKEKMKHIKIAYLTFDDGPSKNTKEILKILKENNVRATFFVNGHPGLEDLYKAIAKDGHVIANHTYSHDYRKVYMSPENFEKDIKKLDKYIEETVGQKPSHIIRYPGGSNNTVSHNYGGPGVMKQIIPYMNNLGYMHFDWNVDSTDASAFRQREDKIINSVLTESRGQHKAVILMHDTDPKTTTVQALPEVIKGLKEQGFIFDVITKDTPQISFTK
>CP027776.1|AVP65060.1|2654789_2655026_+|hypothetical-protein
MREKSQSKLILLLTVTVILFIFSFININRVNTYKNKNESLNNNLKILQTENQKLSSEKEQLDKKHKEIKNKVSTLKGV
>CP027776.1|AVP65059.1|2654176_2654527_+|hypothetical-protein
MYALVLILNDVKKLHSVNEIFYEENCGATNINSRGLGKILLENNLDVPVFAGLRKLIEGDVPYNKTIISVINSEEKKNIITKRIRNTLDIDNKSGIGFMFVLPVIECFGAKTDHYE
>CP027776.1|AVP65058.1|2652991_2654164_+|potassium-transporter
MNPFTGVGIALIVGVLFGKIMNRFKIPAVAGYIIAGLVLGVSGFNLENSVMIEKLSFIGDFALGIIAFNIGSELEVSVIKKLGKPIFIIAFFEAILAFVAVTIITLILGEKIYTALVLGAVASATAPAATVMVLKEMKAKGPLTTTLLGVVAVDDAICLMIYSVASSLAKVFIANKPINAYSIIVPPLAEIFFSLLAGFVLGAILIYILNKCSKDSEIQTLTLGTIIILTGLCIKFNLSSLLASMCLGITVANLSAHNDEVFATIENFASPIITAFFVLAGARLDIKMIPQIGILGVCYLVFRMIGKVSGASLGAKISKAPKTVQKYIGYGLFSQIGVAVGLAIIVSREFKGTGLDTKVLTILLATTIITEIIGPLSTKTAIIKAKEANI
>CP027776.1|AVP65057.1|2652421_2652799_-|hypothetical-protein
MRYILAQYILIIILIIAIGYFLYLIKNRSDDYLENYYGLSDIIINTDYEEEKNRENIKIILRAIASSVYYVEKNFKKEPNNIKENKALEKVEETLKEYKFKGKINEDTLRYLIRINCALMNELYK
>CP027776.1|AVP65067.1|2663032_2665099_-|cupin-domain-containing-protein
MPREFVEYTNDLPIKVSMQNIKKSPIHWHNAMEIIYVLEGSIKITIETESHRVNKQEIGIINPEEAHSIKSITNNNKVLIFQIDTSFFNKYYDIENMFFYTDFSAPEAQKHEKYDILRKYLSTMLCEIAQKGDNYEDVVEEILVDLLYHLINNFHYLIYDEEELKENEVQFERYDRIIKYIYSNYNNKISIQDIARLEFLSSHYLSNEMKNKVGYSFNDFVNLTRVEEAIKLLLDTDKTISEISEELGFSHTRYFNKHFKKHYKCTPMQYRKKYKVDEETYEKLKLYEKLKLKDAYEYLMHYLEDYPRFNYEGKIIKIHVDLSNDTEELDENWHDIINLGSAKEILKGNHVKLIKEFQKYVECEYAIIQNIFSKDMNVFSTEKDRFFNWYEIRQVFEFIYDLDLKPAILIDFHRYEVEFFLTLFKDFIDYFTDFFGDKEIKKWRFYLKNSLDENKKSLESFLKEYEDIEFINWDLDYKEVNNIYDTAYMVPYILNQYLNKKSNVIFLTTFDEIYGGEYINNELFYGGSGIINRQGIKKPSYYAYYLLSKLGNEVIEKGDGYIITKEDDDIQILVYSHSEELESLISLDDLYKRRGLKETAEKKFSINIAALPYNYKIVTYKIDEGKGSSYNNWLSMGKPKRIDEYERDLLIKSSVPNIKLGFAKKSPIYNIVSKIEGYGAFLFILQRV
>CP027776.1|AVP65068.1|2665493_2666990_-|glycerol-kinase
MEKYIMSLDQGTTSSRCIIFNKKGEVVSVAQKEFTQIYPKAGWVEHDPLEIWGKQAGVAGEALNIARISPEQIAGIGITNQRETTVVWNKRTGMPVYNAIVWQCRRTAGYCDELREKNIDKTIKEKTGLMLDAYFSGTKIKWILDNVEGARELAEKGDLLFGNIDTWLIWNMTKGKVHVTDYTNASRTMLFNIHELKWDEELLEIFDIPKSMLPEVKPSSCVYGETDEILFGVSIPISGDAGDQQAALFGQTCFNAGMAKNTYGTGCFLLMNTGEKAVDSKNGLLTTIAVGIDGKVEYALEGSVFIGGAVIQWLRDELRMIKTAQETEKYATAVEDNNGVYLVPAFVGIGAPYWDSYARGTILGLTRGAKKEHIIRAALESMAYQTHDVLKAMEEDSGIELKALKVDGGACQNNFLMQFQSDILGVQVDRPEVVETTALGAAYLAGLAVGYWKDRNEVSQNWAISKSFDPAMEDEKKEKLIKGWHKAVTKSMDWEEKE
>CP027776.1|AVP65069.1|2667280_2667985_-|aquaporin-family-protein
MSIYMAEFLGTMMLIWLGDGVVASVALNKSKGKDGGWIVVTAAWGLAVAIPAYIFGGISGAHMNPAVTVGNAIAGNFPWANVAGYVIAQMLGGFAGAVLVWLTYLPHWKATEDKATKLGVFCTAPAIRDTKANFITEFLATAFLVFGLMGFGQAKMVDGFGPLTAGAFIFVLGLSLGGPTGYAINPARDLAPRIAHAILPIDGKGDSDWKYAWIPVLGPILGGIAGALLFMLVF
>CP027776.1|AVP65070.1|2668526_2668847_+|hypothetical-protein
MLITTTNNIEGKQIKQYKGIVCGEVITGVNFLKDFMAGIRDLVGGRSQGYEEELIRARNEAIDEMMDRAASLGCNSIVGVDIDYEVLGQGGGMLMVTASGTGVITE
>CP027776.1|AVP65071.1|2668960_2669647_-|VanZ-family-protein
MQGIEILLRNVIISIIIILILLKINKKQQNKKGHIIGVLFFIFIMNVIFGLTGISPISGFHTDIRIDEISYIPVVSTLGMVKEVFNTGVVENIPRNETILYLGANIFGNILMFGPLGLLLPLLWRYFRKFWKTVLFGFLVSFTIEFSQLFLARGTDIDDLILNTIGTMLGYLTFVVFHKLFPKFTEKFTVEHGVEKLLWNILPVICVIIPYLVTVILGFYDRAILLAR
>CP027776.1|AVP65072.1|2669791_2670868_-|ABC-transporter-permease
MKSLFRDSLFYKEWKNSKWICLLMTLILFWDKPNNVFGDLSRQKYEMIIDKNFVLDKMWFNQSLLGWNSGKNILILGVITLLCILLFKGEKQSSTCDLLHSMPFTRKDIIVSKIKVGILTITIPFLVNFIIMTFFYFNNKSYIGSFYSDIPKFYSINLLFCLFFFIFLVFMQSIVGQYFAAAVIAPITLFVPNVVAAYIVDLIRLSKGLRYDSPKLMALDQFVRNLNIYDIVNTKALERVEKGPDGEQMRDIDRFIYENFDIKIMILIILIVVFAILSVIIYNRIKLERINQLIIFKPVETVFKLGVAICVGMIFSQIFGYPKGREEIANMPLIYITLLIGTIIGYFISKLIVKFCSK
>CP027776.1|AVP65073.1|2670851_2671748_-|ABC-transporter-ATP-binding-protein
MISISNVSKMLGDKKALNNINLNIEKGSIFGVIGENGAGKTTLIKCMLGIYKQDEGEIKIDGEPVFENTLVKGKIGYVAAEIQYYSSFKVKELVKFYTLTYSTFSHERFKELNKIFKIPENKRIRELSKGMKMRVSLMLNLSIYPEILILDEPTSGLDPIIKRKLINILLEEVSERNTTIFIASHHLDDLERICDSVAIIEKGKIKYANNIEDMKKYIKKLQVLFKDENKTEEIKAWDEIMTVENVGRINYLITNNYSDELQEKLIKSGAEFVEEIDLSLEDMFIYSMEGGKENEKLI
>CP027776.1|AVP65074.1|2671753_2672134_-|GntR-family-transcriptional-regulator
MINIDSRSSKPIYEQIIDGIKENVIRGILKPGDKLPSVRELAVMITTNPNTVSKAYKELEREKIIEVLRGKGTYISDFNPREDEEKMSFLRKELKQLLIEAQYMGIDKKEFLKLIEEIYEDLDGKR
>CP027776.1|AVP65075.1|2672300_2672816_-|hypothetical-protein
MKKKIINILFTVGFVFYILFLLWNIPFKYVSPIEVFSTNRYFSRTLNLIPFYDIFNGNYNSLDIWGNIILFIPLGIYMNIINKYNAIYKRIYKIFAISLIFEASQYIFGIGASDITDIITNTIGGIIGIGIYMVIERVFKEDKKVKNFITICSIVIMIPVAILLIGIYIYN
>CP027776.1|AVP65076.1|2673246_2674959_+|hydroxylamine-reductase
MSMFCYQCQEAAGGRGCTVKGVCGKTEDIAKTQDLIIYVVKGIAIYSSQAREIGLNTSEADKFIVESLFSTITNANFDGKALNARVQKGLKIRQNLKDAIIKAGGSYNSKENKSWTSKFLSVLGIKNDKDEKEIHDAAVWAANNPEDFKKKAETVGVLATENEDIRSLRELLTYGLKGMAAYLEHANNLGYDENSIHAFMAKALVATLDDTLSADELTALVLECGKYGVDVMALLDKANTSTYGNPEITKVNIGVRNNPGILISGHDLKDMEELLKQTEGTGVDVYTHSEMLPANYYPAFKKYKHFVGNYGNAWWKQNEEFEAFNGPILMTTNCIVTPKASYKDRMYTTGVTGFEGVKHINPSKDGKKDFSEIIEHAKRCSSPKEIEKGEIIGGFAHNQVLALAPQVVDAVKTGAIKRFFVMAGCDGRMKSRNYYTDFAKSLPKDTVILTAGCAKYKYNKLDLGDINGIPRVLDAGQCNDSYSLAVIALKLKEVFELEDINELPISYNIAWYEQKAVIVLLALLHLGVKNIHLGPTLPAFLSPNVAKILVENFGIGTISSVDEDIKMFMN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	AP013382	Uncultured Mediterranean phage uvMED DNA, complete genome, group G14, isolate: uvMED-CGR-U-MedDCM-OCT-S45-C13	9086-9119	7	0.794
CP027776_3	3.1\|3131069\|33\|CP027776\|CRISPRCasFinder	3131069-3131101	33	NZ_CP032413	Paenibacillus lautus strain E7593-69 plasmid pAZOPL1, complete sequence	193148-193180	7	0.788
CP027776_3	3.1\|3131069\|33\|CP027776\|CRISPRCasFinder	3131069-3131101	33	NZ_CP020864	Paenibacillus sp. Cedars plasmid unnamed1, complete sequence	16669-16701	7	0.788
CP027776_3	3.1\|3131069\|33\|CP027776\|CRISPRCasFinder	3131069-3131101	33	MT074137	Bacteroides phage DAC16, complete genome	82147-82179	8	0.758
CP027776_3	3.1\|3131069\|33\|CP027776\|CRISPRCasFinder	3131069-3131101	33	NC_021793	Cellulophaga phage phi48:2, complete genome	3764-3796	8	0.758
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NZ_CP014152	Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence	66844-66877	10	0.706
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	149983-150016	10	0.706
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NZ_CP013684	Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence	35977-36010	10	0.706
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NZ_CP013710	Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence	212508-212541	10	0.706
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NC_010379	Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence	5705-5738	10	0.706
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	135615-135648	10	0.706
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NZ_CP013700	Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence	136722-136755	10	0.706
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NZ_CP009595	Bacillus cereus strain 3a plasmid pBFC_3, complete sequence	9067-9100	10	0.706
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NZ_CP009606	Bacillus cereus strain S2-8 plasmid pBFR_2, complete sequence	187780-187813	10	0.706
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NZ_CP053994	Bacillus cereus strain FDAARGOS_780 plasmid unnamed1, complete sequence	261551-261584	10	0.706
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	170878-170911	10	0.706
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NZ_CP053992	Bacillus cereus strain FDAARGOS_781 plasmid unnamed2, complete sequence	244567-244600	10	0.706
CP027776_3	3.1\|3131069\|33\|CP027776\|CRISPRCasFinder	3131069-3131101	33	MN694673	Marine virus AFVG_250M602, complete genome	31008-31040	10	0.697
CP027776_3	3.1\|3131069\|33\|CP027776\|CRISPRCasFinder	3131069-3131101	33	NC_047897	Lactobacillus phage Lenus, complete genome	76435-76467	10	0.697
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	23738-23771	11	0.676
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	19080-19113	11	0.676
CP027776_1	1.1\|424756\|34\|CP027776\|CRISPRCasFinder	424756-424789	34	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	93046-93079	11	0.676

1. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to AP013382 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G14, isolate: uvMED-CGR-U-MedDCM-OCT-S45-C13) position: , mismatch: 7, identity: 0.794

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tacacttgtttttcattacatttttttatatctg	Protospacer
. **  * ********** **************

2. spacer 3.1|3131069|33|CP027776|CRISPRCasFinder matches to NZ_CP032413 (Paenibacillus lautus strain E7593-69 plasmid pAZOPL1, complete sequence) position: , mismatch: 7, identity: 0.788

ggaattatctcctatattaattttctttttaat	CRISPR spacer
gcatcattctcctatattaatgttctttttcat	Protospacer
* * .  ************** ******** **

3. spacer 3.1|3131069|33|CP027776|CRISPRCasFinder matches to NZ_CP020864 (Paenibacillus sp. Cedars plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.788

ggaattatctcctatattaattttctttttaat	CRISPR spacer
gcatcattctcctatattaatgttctttttcat	Protospacer
* * .  ************** ******** **

4. spacer 3.1|3131069|33|CP027776|CRISPRCasFinder matches to MT074137 (Bacteroides phage DAC16, complete genome) position: , mismatch: 8, identity: 0.758

ggaattatctcctatattaattttctttttaat	CRISPR spacer
tatataatctcctatattaattctcttttgata	Protospacer
 . ** ****************.****** *

5. spacer 3.1|3131069|33|CP027776|CRISPRCasFinder matches to NC_021793 (Cellulophaga phage phi48:2, complete genome) position: , mismatch: 8, identity: 0.758

ggaattatc------tcctatattaattttctttttaat	CRISPR spacer
------atcgaccaatcctaaattaattttgtttttaat	Protospacer
      ***      ***** ********* ********

6. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NZ_CP014152 (Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence) position: , mismatch: 10, identity: 0.706

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tttgacagtttttcattagtttttattatatctt	Protospacer
....*   *********** **** ********.

7. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 10, identity: 0.706

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tttgacagtttttcattagtttttattatatctt	Protospacer
....*   *********** **** ********.

8. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NZ_CP013684 (Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence) position: , mismatch: 10, identity: 0.706

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tttgacagtttttcattagtttttattatatctt	Protospacer
....*   *********** **** ********.

9. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NZ_CP013710 (Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence) position: , mismatch: 10, identity: 0.706

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tttgacagtttttcattagtttttattatatctt	Protospacer
....*   *********** **** ********.

10. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NC_010379 (Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence) position: , mismatch: 10, identity: 0.706

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tttgacagtttttcattagtttttattatatctt	Protospacer
....*   *********** **** ********.

11. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 10, identity: 0.706

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tttgacagtttttcattagtttttattatatctt	Protospacer
....*   *********** **** ********.

12. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NZ_CP013700 (Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence) position: , mismatch: 10, identity: 0.706

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tttgacagtttttcattagtttttattatatctt	Protospacer
....*   *********** **** ********.

13. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NZ_CP009595 (Bacillus cereus strain 3a plasmid pBFC_3, complete sequence) position: , mismatch: 10, identity: 0.706

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tcaaaatccttttctttagatttttttcaacact	Protospacer
.* *****.***** ************  *. ..

14. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NZ_CP009606 (Bacillus cereus strain S2-8 plasmid pBFR_2, complete sequence) position: , mismatch: 10, identity: 0.706

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tcaaaatccttttctttagatttttttcaacact	Protospacer
.* *****.***** ************  *. ..

15. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NZ_CP053994 (Bacillus cereus strain FDAARGOS_780 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tcaaaatccttttctttagatttttttcaacact	Protospacer
.* *****.***** ************  *. ..

16. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 10, identity: 0.706

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
ctcaaaactttttcattaggttttttaaagataa	Protospacer
*.**** ************.****** * . .

17. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NZ_CP053992 (Bacillus cereus strain FDAARGOS_781 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.706

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tcaaaatccttttctttagatttttttcaacact	Protospacer
.* *****.***** ************  *. ..

18. spacer 3.1|3131069|33|CP027776|CRISPRCasFinder matches to MN694673 (Marine virus AFVG_250M602, complete genome) position: , mismatch: 10, identity: 0.697

ggaattatctcctatattaattttctttttaat	CRISPR spacer
agttttatctcctatattaatttcgtttactga	Protospacer
.*  *******************. *** . .

19. spacer 3.1|3131069|33|CP027776|CRISPRCasFinder matches to NC_047897 (Lactobacillus phage Lenus, complete genome) position: , mismatch: 10, identity: 0.697

ggaattatctcctatattaattttctttttaat	CRISPR spacer
attattatctcctaaattagttttcttccgcac	Protospacer
.  *********** ****.*******..  *.

20. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 11, identity: 0.676

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tttgacagcttttcattagtttttattatatctt	Protospacer
....*   .********** **** ********.

21. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 11, identity: 0.676

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tttgatagcttttcattagtttttattatatctt	Protospacer
....*   .********** **** ********.

22. spacer 1.1|424756|34|CP027776|CRISPRCasFinder matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 11, identity: 0.676

cccaaatctttttcattagatttttttatatctc	CRISPR spacer
tttgatagcttttcattagtttttattatatctt	Protospacer
....*   .********** **** ********.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

356671 : 374194

Streptococcus_phage(100.0%)

integrase

attL 355602:355616|attR 378678:378692

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
355602:355616	attL	NA	NA	NA	NA
AVP63019.1\|356671_356986_+	DUF961 domain-containing protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
AVP63020.1\|357001_357388_+	DUF961 domain-containing protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
AVP63021.1\|357416_358802_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
AVP63022.1\|358804_358957_+	conjugal transfer protein	NA	NA	NA	NA
AVP63023.1\|358979_360185_+	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
AVP63024.1\|360227_360449_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
AVP63025.1\|360565_361063_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
AVP63026.1\|361037_361544_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
AVP63027.1\|361527_363975_+	ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
AVP63028.1\|363977_366155_+	hypothetical protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
AVP63029.1\|366151_367153_+	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
AVP63030.1\|367149_368082_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.1e-171	100.0
AVP63031.1\|368356_368443_+	tetracycline resistance protein	NA	NA	NA	NA
AVP63032.1\|368458_370378_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	100.0
AVP63033.1\|370478_370664_+	conjugal transfer protein	D0R0F6	Streptococcus_phage	3.9e-17	67.9
AVP63034.1\|370723_371077_-	XRE family transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
AVP66380.1\|371281_371353_+	hypothetical protein	NA	NA	NA	NA
AVP63035.1\|371581_372004_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
AVP63036.1\|372000_372231_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
AVP63037.1\|372456_372708_-	hypothetical protein	NA	NA	NA	NA
AVP63038.1\|372691_372895_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
AVP63039.1\|372976_374194_+\|integrase	site-specific integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
378678:378692	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1383421 : 1391084

Bacillus_phage(37.5%)

integrase

attL 1382718:1382732|attR 1388391:1388405

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1382718:1382732	attL	NA	NA	NA	NA
AVP63903.1\|1383421_1383781_-	hypothetical protein	A0A0A7S0N7	Clostridium_phage	1.4e-10	45.4
AVP63904.1\|1383829_1384096_-	hypothetical protein	NA	NA	NA	NA
AVP63905.1\|1384112_1384295_-	hypothetical protein	A0A0A7RTQ2	Clostridium_phage	5.0e-09	53.3
AVP63906.1\|1384336_1384636_-	hypothetical protein	NA	NA	NA	NA
AVP63907.1\|1384697_1384919_-	XRE family transcriptional regulator	Q9ZXD1	Bacillus_phage	3.0e-08	40.3
AVP66414.1\|1385159_1385582_+	transcriptional regulator	Q786F1	Bacillus_phage	4.0e-25	48.9
AVP63908.1\|1385600_1386047_+	ImmA/IrrE family metallo-endopeptidase	S6B1N5	Thermus_phage	1.5e-27	44.4
AVP63909.1\|1386098_1387181_+\|integrase	site-specific integrase	A0A1C8E994	Bacillus_phage	1.6e-25	28.3
AVP63910.1\|1387332_1389003_-	penicillin-binding protein 2	NA	NA	NA	NA
1388391:1388405	attR	NA	NA	NA	NA
AVP63911.1\|1389088_1389709_-	uridine kinase	A0A1V0SAA3	Catovirus	7.4e-36	39.6
AVP63912.1\|1389857_1391084_-	peptidase U32	Q6DW11	Phage_TP	8.5e-52	37.3

DBSCAN-SWA_3

1595852 : 1618852

Clostridium_phage(61.11%)

capsid,portal,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVP64100.1\|1595852_1597586_+	hypothetical protein	A0A1V0DZW7	Clostridioides_phage	1.0e-244	70.8
AVP64101.1\|1597589_1598858_+\|portal	phage portal protein	A0A1V0DZW8	Clostridioides_phage	5.6e-115	52.9
AVP64102.1\|1599978_1600146_+	hypothetical protein	NA	NA	NA	NA
AVP64103.1\|1600281_1600875_+	hypothetical protein	E5DV52	Deep-sea_thermophilic_phage	1.4e-15	34.7
AVP64104.1\|1600890_1601781_+\|capsid	phage major capsid protein	A0A0H3U2U7	Staphylococcus_phage	2.2e-57	42.7
AVP64105.1\|1602005_1602272_+	hypothetical protein	NA	NA	NA	NA
AVP64106.1\|1602273_1602684_+	hypothetical protein	NA	NA	NA	NA
AVP64107.1\|1602683_1603028_+\|capsid	capsid protein	F6K8R4	Clostridium_phage	2.3e-15	42.5
AVP64108.1\|1603024_1603456_+	chloramphenicol resistance protein	A0A0A8WJ92	Clostridium_phage	2.2e-39	55.2
AVP64109.1\|1603456_1603963_+	hypothetical protein	NA	NA	NA	NA
AVP64110.1\|1603962_1604307_+	AP endonuclease	NA	NA	NA	NA
AVP64111.1\|1604306_1604900_+	hypothetical protein	A0A1J1J8Y5	Escherichia_phage	1.1e-65	60.9
AVP64112.1\|1604958_1605492_+	hypothetical protein	NA	NA	NA	NA
AVP64113.1\|1605540_1605690_+	Com family DNA-binding transcriptional regulator	NA	NA	NA	NA
AVP64114.1\|1606179_1606911_+	hypothetical protein	O64121	Bacillus_phage	4.2e-14	31.3
AVP64115.1\|1607144_1609286_+\|tail	phage tail tape measure protein	Q0SPL2	Clostridium_phage	1.9e-70	59.5
AVP64116.1\|1609285_1609963_+\|tail	phage tail protein	A0A0A7RWN1	Clostridium_phage	3.3e-45	43.5
AVP64117.1\|1609962_1611630_+	endopeptidase	A0A0A7RUI9	Clostridium_phage	9.4e-78	42.5
AVP64118.1\|1611644_1613009_+	DUF2479 domain-containing protein	A0A0A7S181	Clostridium_phage	2.0e-81	77.6
AVP64119.1\|1613010_1615731_+	hypothetical protein	I1TJW8	Clostridium_phage	3.4e-242	51.6
AVP64120.1\|1615743_1615944_+	D-alanyl-D-alanine carboxypeptidase	I1TJW9	Clostridium_phage	3.0e-07	48.4
AVP64121.1\|1615943_1616090_+	XkdX family protein	A0A0A7RTH5	Clostridium_phage	3.1e-09	62.2
AVP64122.1\|1616160_1616439_+	hypothetical protein	A0A2H4J1Q4	uncultured_Caudovirales_phage	2.5e-20	53.8
AVP64123.1\|1616441_1616636_+	hypothetical protein	NA	NA	NA	NA
AVP64124.1\|1616678_1617497_+	peptidoglycan-binding domain-containing protein	A0A0A7RVQ3	Clostridium_phage	1.2e-25	43.2
AVP64125.1\|1617600_1618266_+	hypothetical protein	NA	NA	NA	NA
AVP64126.1\|1618438_1618852_-	HicB family protein	A0A090DBV2	Clostridium_phage	6.4e-20	39.6

DBSCAN-SWA_4

1651282 : 1670339

Clostridium_phage(85.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVP64164.1\|1651282_1651486_+	small acid-soluble spore protein	G3MAF8	Bacillus_virus	1.5e-09	43.7
AVP64165.1\|1652052_1652202_-	hypothetical protein	NA	NA	NA	NA
AVP64166.1\|1652460_1652871_-	XRE family transcriptional regulator	A0A0A7RUJ5	Clostridium_phage	8.7e-09	54.7
AVP64167.1\|1653063_1653273_+	XRE family transcriptional regulator	NA	NA	NA	NA
AVP64168.1\|1653334_1653547_+	XRE family transcriptional regulator	NA	NA	NA	NA
AVP64169.1\|1653628_1654552_+	hypothetical protein	A0A141E0P9	Streptococcus_phage	4.3e-40	42.1
AVP64170.1\|1654493_1655342_+	DNA replication protein	A0A1B1P7U2	Bacillus_phage	4.4e-39	39.5
AVP64171.1\|1655398_1655719_+	hypothetical protein	NA	NA	NA	NA
AVP64172.1\|1655834_1656356_+	hypothetical protein	A0A0A7RVS1	Clostridium_phage	1.2e-36	50.0
AVP64173.1\|1656991_1657276_+	hypothetical protein	A0A0A7S0R4	Clostridium_phage	3.5e-25	62.2
AVP64174.1\|1657275_1657641_+	hypothetical protein	A0A0A7RW73	Clostridium_phage	1.8e-34	57.9
AVP64175.1\|1657645_1657993_+	hypothetical protein	A0A0A7RU51	Clostridium_phage	1.0e-34	60.6
AVP64176.1\|1657998_1658418_+	hypothetical protein	A0A0A7RU17	Clostridium_phage	2.7e-58	72.7
AVP64177.1\|1658422_1659310_+	hypothetical protein	A0A0A7RTZ9	Clostridium_phage	5.3e-120	74.7
AVP64178.1\|1659323_1659740_+	esterase	A0A0A7S0S0	Clostridium_phage	1.3e-44	70.5
AVP66423.1\|1659774_1659942_+	hypothetical protein	A0A0A7RW80	Clostridium_phage	4.3e-15	68.5
AVP64179.1\|1660122_1661664_+	hypothetical protein	A0A0A7RU22	Clostridium_phage	7.0e-03	38.0
AVP64180.1\|1661676_1662111_+	hypothetical protein	NA	NA	NA	NA
AVP64181.1\|1662097_1663183_+	hypothetical protein	NA	NA	NA	NA
AVP64182.1\|1663195_1663537_+	hypothetical protein	A0A0A7S0S4	Clostridium_phage	1.8e-15	54.3
AVP64183.1\|1663551_1664901_+	caspase family protein	A0A0A7RW86	Clostridium_phage	9.3e-76	74.6
AVP64184.1\|1664902_1665883_+	hypothetical protein	A0A0A7RU61	Clostridium_phage	1.5e-107	59.8
AVP64185.1\|1665905_1667159_+	hypothetical protein	A0A0A7RU28	Clostridium_phage	3.3e-192	78.7
AVP64186.1\|1667173_1669069_+	hypothetical protein	A0A0A7RU09	Clostridium_phage	7.1e-106	53.7
AVP64187.1\|1669074_1669329_+	hypothetical protein	A0A0A7S0T0	Clostridium_phage	1.1e-33	81.0
AVP64188.1\|1669340_1670339_+	hypothetical protein	A0A0A7RW91	Clostridium_phage	2.1e-141	71.7

DBSCAN-SWA_5

1894167 : 1972574

Erysipelothrix_phage(67.35%)

holin,tail,terminase,head,capsid,protease,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVP64418.1\|1894167_1895463_+\|protease	serine protease	NA	NA	NA	NA
AVP64419.1\|1895464_1897453_+	excinuclease ABC subunit UvrB	NA	NA	NA	NA
AVP64420.1\|1897471_1900294_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	9.7e-309	56.2
AVP64421.1\|1900392_1900830_+	FHA domain-containing protein	NA	NA	NA	NA
AVP64422.1\|1900840_1902070_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
AVP64423.1\|1902074_1903502_+	penicillin-binding protein 2	NA	NA	NA	NA
AVP64424.1\|1903530_1904427_+	HD domain-containing protein	NA	NA	NA	NA
AVP64425.1\|1904617_1905226_+	metal-dependent hydrolase	NA	NA	NA	NA
AVP64426.1\|1905239_1907096_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
AVP64427.1\|1907155_1907887_+	phosphatase	NA	NA	NA	NA
AVP64428.1\|1907955_1908876_+	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
AVP64429.1\|1908995_1909880_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	6.9e-11	33.1
AVP64430.1\|1909876_1911214_+	YvcK family protein	A1IMD5	Streptococcus_phage	4.3e-49	36.3
AVP64431.1\|1911220_1912168_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	9.2e-46	35.6
AVP64432.1\|1912327_1915885_+	DNA polymerase III subunit alpha	A0A0K1Y8F0	Streptomyces_phage	4.6e-207	37.6
AVP64433.1\|1916127_1917087_+	6-phosphofructokinase	NA	NA	NA	NA
AVP64434.1\|1917120_1918878_+	pyruvate kinase	NA	NA	NA	NA
AVP64435.1\|1919023_1920034_+	aldo/keto reductase	NA	NA	NA	NA
AVP64436.1\|1920364_1920721_+	DUF1540 domain-containing protein	NA	NA	NA	NA
AVP64437.1\|1920947_1922333_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	3.3e-100	41.4
AVP64438.1\|1922530_1925038_-	type III deoxyribonuclease	NA	NA	NA	NA
AVP64439.1\|1925038_1927348_-	site-specific DNA-methyltransferase	Q1MVP0	Enterobacteria_phage	9.2e-31	28.4
AVP64440.1\|1927365_1929006_-	DUF2326 domain-containing protein	NA	NA	NA	NA
AVP64441.1\|1928983_1929223_-	hypothetical protein	NA	NA	NA	NA
AVP64442.1\|1929206_1930445_-	hypothetical protein	NA	NA	NA	NA
AVP64443.1\|1930469_1930688_-	transcriptional regulator	A0A2K5B261	Erysipelothrix_phage	4.9e-11	51.5
AVP64444.1\|1931045_1931711_+	flagellar biosynthesis protein FliA	A0A2K5B267	Erysipelothrix_phage	1.3e-14	31.4
AVP64445.1\|1931758_1931977_+	hypothetical protein	A0A2I4R673	Erysipelothrix_phage	2.2e-19	61.1
AVP64446.1\|1931951_1932275_+	rRNA biogenesis protein rrp5	A0A2K5B2A7	Erysipelothrix_phage	7.0e-22	61.7
AVP64447.1\|1932267_1933407_+	DUF2800 domain-containing protein	A0A2K5B2A8	Erysipelothrix_phage	4.5e-180	80.2
AVP64448.1\|1933408_1933957_+	DUF2815 domain-containing protein	A0A2K5B2A9	Erysipelothrix_phage	1.2e-90	89.0
AVP64449.1\|1934029_1935964_+	hypothetical protein	A0A2K5B2B0	Erysipelothrix_phage	3.5e-294	74.6
AVP64450.1\|1936057_1936810_+	phage antirepressor Ant	A0A2H4IZX7	uncultured_Caudovirales_phage	3.1e-60	48.6
AVP64451.1\|1936809_1937244_+	DUF4406 domain-containing protein	A0A2K5B270	Erysipelothrix_phage	3.4e-56	71.5
AVP64452.1\|1937240_1939607_+	hypothetical protein	A0A1W6JQ82	Corynebacterium_phage	1.6e-243	51.8
AVP64453.1\|1939825_1940107_+	nuclease	A0A2K5B272	Erysipelothrix_phage	9.7e-28	68.9
AVP64454.1\|1940060_1941449_+	DEAD/DEAH box helicase	A0A2K5B273	Erysipelothrix_phage	1.5e-185	79.1
AVP64455.1\|1941448_1941667_+	hypothetical protein	A0A2K5B274	Erysipelothrix_phage	2.1e-14	57.1
AVP64456.1\|1941663_1942077_+	DUF1492 domain-containing protein	A0A2K5B275	Erysipelothrix_phage	5.1e-25	43.4
AVP64457.1\|1942232_1942592_+	HNH endonuclease	A0A2K5B276	Erysipelothrix_phage	2.3e-42	66.1
AVP64458.1\|1942703_1943255_+\|terminase	terminase	A0A2K5B277	Erysipelothrix_phage	2.4e-78	76.5
AVP64459.1\|1943257_1944442_+	methionine adenosyltransferase	A0A2K5B278	Erysipelothrix_phage	1.3e-177	78.2
AVP64460.1\|1944431_1945682_+	DNA modification methylase	A0A2I4R670	Erysipelothrix_phage	4.4e-189	76.8
AVP64461.1\|1945782_1946475_+	virulence protein	A0A2K5B280	Erysipelothrix_phage	2.4e-51	51.1
AVP64462.1\|1946471_1946699_+	DUF4314 domain-containing protein	E4ZFL7	Streptococcus_phage	1.4e-08	41.2
AVP64463.1\|1946835_1947735_+	amidoligase	A0A2K9V489	Faecalibacterium_phage	1.9e-53	41.9
AVP64464.1\|1947773_1948232_+	gamma-glutamylcyclotransferase	G3MAQ5	Bacillus_virus	5.3e-15	33.6
AVP64465.1\|1948224_1948413_+	DUF5049 domain-containing protein	NA	NA	NA	NA
AVP64466.1\|1948501_1950106_+\|terminase	terminase large subunit	A0A2K5B285	Erysipelothrix_phage	1.2e-266	83.3
AVP64467.1\|1950149_1951394_+\|portal	phage portal protein	A0A2K5B287	Erysipelothrix_phage	1.1e-179	72.1
AVP64468.1\|1951394_1952084_+\|protease	Clp protease ClpP	Q6DMU1	Streptococcus_phage	1.1e-72	63.2
AVP64469.1\|1952103_1953297_+\|capsid	phage major capsid protein	A0A2I4R671	Erysipelothrix_phage	5.4e-184	80.6
AVP64470.1\|1953309_1953522_+	Head fiber protein	A0A2K5B289	Erysipelothrix_phage	3.6e-19	68.9
AVP64471.1\|1953548_1953869_+\|head,tail	phage gp6-like head-tail connector protein	A0A2K5B290	Erysipelothrix_phage	6.3e-39	81.0
AVP64472.1\|1953870_1954206_+\|head,tail	head-tail adaptor protein	A0A2K5B291	Erysipelothrix_phage	5.8e-27	54.5
AVP64473.1\|1954211_1954643_+	hypothetical protein	A0A2K5B292	Erysipelothrix_phage	3.9e-44	60.1
AVP64474.1\|1954639_1954981_+	hypothetical protein	A0A2K5B293	Erysipelothrix_phage	3.1e-28	52.3
AVP64475.1\|1954984_1955575_+\|tail	phage tail protein	A0A2K5B294	Erysipelothrix_phage	5.0e-74	70.5
AVP64476.1\|1955586_1955973_+	hypothetical protein	A0A2K5B295	Erysipelothrix_phage	6.2e-41	70.4
AVP64477.1\|1956175_1958596_+\|tail	phage tail protein	A0A2K5B297	Erysipelothrix_phage	3.3e-23	46.9
AVP64478.1\|1958609_1959461_+\|tail	phage tail family protein	E2ELJ6	Clostridium_phage	8.9e-40	34.4
AVP64479.1\|1959463_1961401_+	hypothetical protein	NA	NA	NA	NA
AVP64480.1\|1961416_1961920_+	hypothetical protein	A0A1C9LWP9	Streptomyces_phage	5.6e-10	37.7
AVP64481.1\|1961933_1964288_+	hypothetical protein	NA	NA	NA	NA
AVP64482.1\|1964362_1964803_+\|holin	holin	A0A2K5B2A2	Erysipelothrix_phage	4.6e-48	65.2
AVP64483.1\|1964799_1966194_+	hypothetical protein	NA	NA	NA	NA
AVP64484.1\|1966211_1966913_+	amidase	H7BVK7	unidentified_phage	3.9e-49	44.3
AVP64485.1\|1967109_1967346_+	hypothetical protein	A0A2K5B2B1	Erysipelothrix_phage	3.0e-06	50.0
AVP64486.1\|1967407_1968970_+	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	2.3e-158	54.1
AVP64487.1\|1968970_1969384_+	recombinase	NA	NA	NA	NA
AVP64488.1\|1969387_1970959_+	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	4.6e-175	61.7
AVP64489.1\|1971070_1971670_+	TetR family transcriptional regulator	NA	NA	NA	NA
AVP66425.1\|1971722_1972574_+	alpha/beta hydrolase	A0A1J0GNR5	Mycobacterium_phage	4.3e-10	28.7

DBSCAN-SWA_6

3532537 : 3542160

Synechococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVP66462.1\|3532537_3535108_+	selenium-dependent xanthine dehydrogenase	A0A0P0IVM8	Acinetobacter_phage	1.1e-11	33.1
AVP65837.1\|3535782_3536262_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	4.4e-28	50.0
AVP65838.1\|3536261_3536966_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	4.6e-42	42.1
AVP65839.1\|3537080_3538529_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	6.1e-57	34.7
AVP65840.1\|3538700_3539696_+	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	2.0e-67	42.8
AVP65841.1\|3539823_3540441_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.2e-25	39.3
AVP65842.1\|3540660_3542160_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase	Q58MG4	Prochlorococcus_phage	9.4e-69	46.6

DBSCAN-SWA_7

3555872 : 3564898

Staphylococcus_phage(50.0%)

integrase

attL 3559701:3559717|attR 3564974:3564990

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVP65852.1\|3555872_3556526_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	4.1e-37	39.4
AVP65853.1\|3556644_3557850_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	4.8e-116	53.9
AVP65854.1\|3557881_3558346_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	8.8e-42	57.4
AVP65855.1\|3558679_3559432_-	hypothetical protein	NA	NA	NA	NA
AVP65856.1\|3559457_3561317_-	LTA synthase family protein	W6LM83	Streptococcus_phage	4.2e-50	28.6
3559701:3559717	attL	NA	NA	NA	NA
AVP65857.1\|3561634_3562093_+	DNA-binding protein	NA	NA	NA	NA
AVP65858.1\|3562320_3563679_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	9.4e-60	31.1
AVP65859.1\|3563758_3564898_-\|integrase	site-specific integrase	A0A2I7SCV1	Paenibacillus_phage	1.3e-115	54.6
3564974:3564990	attR	NA	NA	NA	NA

DBSCAN-SWA_8

3758682 : 3777314

Clostridium_phage(30.77%)

tail,head,capsid,portal,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVP66020.1\|3758682_3758886_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
AVP66021.1\|3759267_3759477_-	hypothetical protein	NA	NA	NA	NA
AVP66022.1\|3759548_3760649_-	hypothetical protein	NA	NA	NA	NA
AVP66023.1\|3760912_3761467_-	hypothetical protein	A0A2H4JF32	uncultured_Caudovirales_phage	4.9e-47	61.4
AVP66024.1\|3761494_3762475_-	hypothetical protein	NA	NA	NA	NA
AVP66025.1\|3763429_3764587_-	hypothetical protein	A0A0C5AMZ5	Paenibacillus_phage	1.7e-65	35.7
AVP66026.1\|3764592_3765462_-\|tail	phage tail family protein	E2ELJ6	Clostridium_phage	1.6e-44	38.7
AVP66027.1\|3765451_3768100_-\|tail	phage tail tape measure protein	A0A0H4TEZ5	Erysipelothrix_phage	9.1e-75	52.3
AVP66028.1\|3768159_3768318_-	Com family DNA-binding transcriptional regulator	NA	NA	NA	NA
AVP66029.1\|3768358_3768847_-	hypothetical protein	A0A0K2CP90	Brevibacillus_phage	9.3e-10	32.7
AVP66030.1\|3768903_3769497_-	hypothetical protein	F6K8R8	Clostridium_phage	2.0e-62	58.9
AVP66031.1\|3769496_3769841_-	AP endonuclease	A0A1J1JCF3	Escherichia_phage	9.5e-17	46.7
AVP66032.1\|3769840_3770350_-	hypothetical protein	NA	NA	NA	NA
AVP66033.1\|3770350_3770785_-	chloramphenicol resistance protein	A0A0A8WJ92	Clostridium_phage	3.6e-37	51.7
AVP66034.1\|3770781_3771126_-\|capsid	capsid protein	F6K8R4	Clostridium_phage	1.8e-15	41.2
AVP66035.1\|3771125_3771536_-	hypothetical protein	NA	NA	NA	NA
AVP66036.1\|3771537_3771804_-	hypothetical protein	NA	NA	NA	NA
AVP66037.1\|3772030_3772921_-\|capsid	phage major capsid protein	A0A0H3U2U7	Staphylococcus_phage	5.8e-58	42.9
AVP66038.1\|3772936_3773530_-	DUF4355 domain-containing protein	A0A1L2K2N1	Aeribacillus_phage	3.8e-21	38.9
AVP66039.1\|3773589_3774309_-\|head	phage head morphogenesis protein	NA	NA	NA	NA
AVP66040.1\|3774308_3775577_-\|portal	phage portal protein	A0A1V0DZW8	Clostridioides_phage	4.3e-99	47.8
AVP66041.1\|3775580_3777314_-	hypothetical protein	A0A1V0DZW7	Clostridioides_phage	5.3e-249	72.0

DBSCAN-SWA_9

4099011 : 4109708

uncultured_Caudovirales_phage(30.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVP66325.1\|4099011_4099596_-	molybdopterin-guanine dinucleotide biosynthesis protein A	A0A2H4J819	uncultured_Caudovirales_phage	1.2e-32	44.0
AVP66326.1\|4099598_4099931_-	nucleotide pyrophosphohydrolase	A0A2H4J7H8	uncultured_Caudovirales_phage	3.6e-45	79.8
AVP66327.1\|4099931_4100141_-	hypothetical protein	NA	NA	NA	NA
AVP66328.1\|4100246_4101074_-	DNA adenine methylase	A7YGL3	Campylobacter_phage	5.6e-31	35.8
AVP66329.1\|4101708_4101912_-	hypothetical protein	NA	NA	NA	NA
AVP66330.1\|4101968_4102376_-	single-stranded DNA-binding protein	Q8SBL5	Clostridium_phage	1.8e-27	44.2
AVP66331.1\|4102379_4103000_-	HD domain-containing protein	A0A2H4J8L1	uncultured_Caudovirales_phage	5.7e-28	37.3
AVP66332.1\|4103013_4103727_-	MBL fold metallo-hydrolase	A8ATK9	Listeria_phage	8.2e-47	44.1
AVP66333.1\|4103726_4104473_-	phage recombination protein Bet	A8ATK8	Listeria_phage	1.2e-53	51.5
AVP66334.1\|4104511_4105450_-	hypothetical protein	D7RWF8	Brochothrix_phage	1.2e-29	51.2
AVP66335.1\|4105559_4107653_+	hypothetical protein	M4ZRP4	Bacillus_phage	1.4e-14	30.4
AVP66336.1\|4107842_4109708_+	nucleoside-diphosphate sugar epimerase	A0A1M7XU65	Cedratvirus	7.0e-13	29.9

DBSCAN-SWA_10

4115603 : 4120170

Clostridium_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVP66341.1\|4115603_4116533_+	hypothetical protein	A0A0A7RUP3	Clostridium_phage	1.3e-65	50.8
AVP66342.1\|4116532_4117246_+	MBL fold metallo-hydrolase	A8ATK9	Listeria_phage	2.0e-45	42.8
AVP66343.1\|4117259_4117880_+	metal-dependent phosphohydrolase	A0A2H4J8L1	uncultured_Caudovirales_phage	1.6e-30	38.3
AVP66344.1\|4117882_4118293_+	single-stranded DNA-binding protein	Q8SBL5	Clostridium_phage	8.3e-28	44.0
AVP66345.1\|4118331_4118601_+	DNA-entry nuclease	A0A0A7RWV6	Clostridium_phage	4.3e-09	37.7
AVP66346.1\|4118681_4118918_+	hypothetical protein	NA	NA	NA	NA
AVP66347.1\|4119178_4119511_+	nucleotide pyrophosphohydrolase	A0A2H4J7H8	uncultured_Caudovirales_phage	3.9e-44	78.9
AVP66348.1\|4119513_4120170_+	ERCC4-type nuclease	F8UBF1	Clostridium_phage	6.2e-41	42.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP027776

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection