CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP028102	Fusobacterium mortiferum ATCC 9817 chromosome, complete genome	0 crisprs	cas14j,csm6,csa3,cas3,cas4,DEDDh,DinG,WYL,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas2,cas1	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1294640 : 1316146

Clostridium_phage(36.36%)

terminase,tail,protease,holin,head,plate,portal,capsid

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ18737.1\|1294640_1295120_-\|holin	holin	M9Q253	Clostridium_phage	1.8e-13	36.3
AVQ18738.1\|1295130_1295376_-	hypothetical protein	NA	NA	NA	NA
AVQ18739.1\|1295397_1295811_-	M15 family peptidase	A0A0E3Y6B0	Fusobacterium_phage	3.1e-30	48.1
AVQ18740.1\|1295907_1296480_-	hypothetical protein	NA	NA	NA	NA
AVQ18741.1\|1296632_1296950_-	hypothetical protein	NA	NA	NA	NA
AVQ18742.1\|1296968_1297901_-	hypothetical protein	NA	NA	NA	NA
AVQ18743.1\|1298440_1299187_-	hypothetical protein	A0A0F6R6B6	Escherichia_coli_O157_typing_phage	7.1e-09	29.3
AVQ18744.1\|1299199_1299988_-	hypothetical protein	NA	NA	NA	NA
AVQ18745.1\|1300000_1300549_-	hypothetical protein	NA	NA	NA	NA
AVQ18746.1\|1300553_1300814_-	hypothetical protein	NA	NA	NA	NA
AVQ18747.1\|1300813_1301356_-	DUF2313 domain-containing protein	NA	NA	NA	NA
AVQ18748.1\|1301345_1302440_-\|plate	baseplate J protein	A0A0A7RUN3	Clostridium_phage	7.6e-60	39.8
AVQ18749.1\|1302432_1302885_-	DUF2634 domain-containing protein	NA	NA	NA	NA
AVQ18750.1\|1302896_1303319_-	DUF2577 domain-containing protein	NA	NA	NA	NA
AVQ18751.1\|1303308_1304262_-	hypothetical protein	NA	NA	NA	NA
AVQ18752.1\|1304266_1304665_-	hypothetical protein	NA	NA	NA	NA
AVQ18753.1\|1304666_1304981_-	hypothetical protein	NA	NA	NA	NA
AVQ18754.1\|1304990_1307204_-	hypothetical protein	NA	NA	NA	NA
AVQ18755.1\|1307397_1307826_-	hypothetical protein	NA	NA	NA	NA
AVQ18756.1\|1307866_1308274_-	hypothetical protein	NA	NA	NA	NA
AVQ18757.1\|1308284_1309376_-\|tail	phage tail sheath protein	A0A090D804	Clostridium_phage	7.9e-25	26.0
AVQ18758.1\|1309362_1309812_-	hypothetical protein	NA	NA	NA	NA
AVQ18759.1\|1309820_1310225_-	hypothetical protein	NA	NA	NA	NA
AVQ18760.1\|1310211_1310556_-\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
AVQ18761.1\|1310548_1310833_-\|head,tail	phage gp6-like head-tail connector protein	A0A2H4J6E5	uncultured_Caudovirales_phage	2.4e-05	40.7
AVQ18762.1\|1310847_1311990_-\|capsid	phage major capsid protein	Q9ZXF6	Bacillus_phage	5.5e-69	39.6
AVQ18763.1\|1311994_1312741_-\|protease	Clp protease ClpP	A0A0A8WFM9	Clostridium_phage	1.6e-45	45.7
AVQ20072.1\|1312712_1313981_-\|portal	phage portal protein	A6M949	Geobacillus_virus	8.4e-87	45.0
AVQ18764.1\|1313993_1315691_-\|terminase	terminase large subunit	A6M948	Geobacillus_virus	3.9e-119	40.6
AVQ18765.1\|1315687_1316146_-\|terminase	terminase	M1PKP2	Streptococcus_phage	1.8e-07	31.0

DBSCAN-SWA_2

1441903 : 1471102

Fusobacterium_phage(87.5%)

terminase,integrase,tail,protease,holin,plate,portal,capsid

attL 1449003:1449018|attR 1469280:1469295

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ18889.1\|1441903_1442983_+	hypothetical protein	A0A0E3U246	Fusobacterium_phage	8.5e-72	43.5
AVQ18890.1\|1443159_1444479_+	chromosome partitioning protein ParB	A0A0E3Y5D8	Fusobacterium_phage	1.9e-137	56.7
AVQ18891.1\|1444471_1445221_+	helix-turn-helix domain-containing protein	A0A0E3Y615	Fusobacterium_phage	1.9e-33	42.9
AVQ18892.1\|1445366_1445831_+	hypothetical protein	A0A0E3Y4U4	Fusobacterium_phage	7.5e-33	53.3
AVQ18893.1\|1445811_1447590_+\|terminase	phage terminase large subunit family protein	A0A0E3U2N4	Fusobacterium_phage	4.9e-242	68.7
AVQ18894.1\|1447586_1447805_+	hypothetical protein	A0A0E3U247	Fusobacterium_phage	7.8e-17	54.2
AVQ18895.1\|1447815_1449315_+\|portal	phage portal protein	A0A0E3Y693	Fusobacterium_phage	1.4e-176	65.8
1449003:1449018	attL	NA	NA	NA	NA
AVQ18896.1\|1449307_1450393_+\|protease	Clp protease ClpP	A0A0E3Y6E9	Fusobacterium_phage	5.4e-74	43.8
AVQ18897.1\|1450403_1450736_+	hypothetical protein	NA	NA	NA	NA
AVQ18898.1\|1450748_1451774_+\|capsid	minor capsid protein E	A0A0E3U2N5	Fusobacterium_phage	3.5e-99	55.6
AVQ18899.1\|1451804_1452047_+	hypothetical protein	NA	NA	NA	NA
AVQ18900.1\|1452012_1452366_+	hypothetical protein	A0A0E3Y618	Fusobacterium_phage	4.5e-14	37.3
AVQ18901.1\|1452367_1452940_+	hypothetical protein	A0A0E3Y4U7	Fusobacterium_phage	1.5e-22	36.5
AVQ18902.1\|1452939_1453440_+	hypothetical protein	NA	NA	NA	NA
AVQ18903.1\|1453429_1453714_+	hypothetical protein	NA	NA	NA	NA
AVQ18904.1\|1453713_1455132_+\|tail	phage tail sheath family protein	A0A0E3U251	Fusobacterium_phage	3.2e-151	54.7
AVQ18905.1\|1455156_1455675_+\|tail	phage tail protein	A0A0E3Y6F4	Fusobacterium_phage	2.3e-43	52.6
AVQ18906.1\|1455684_1456068_+	hypothetical protein	A0A0E3Y5E7	Fusobacterium_phage	6.4e-14	43.8
AVQ18907.1\|1456192_1456522_+	hypothetical protein	NA	NA	NA	NA
AVQ18908.1\|1456584_1459620_+\|tail	phage tail tape measure protein	A0A0E3U2N9	Fusobacterium_phage	3.6e-128	42.0
AVQ18909.1\|1459609_1459819_+	hypothetical protein	NA	NA	NA	NA
AVQ18910.1\|1459815_1460886_+	late control protein D	A0A0E3U253	Fusobacterium_phage	8.4e-88	45.4
AVQ18911.1\|1460878_1461400_+\|plate	phage baseplate assembly protein V	NA	NA	NA	NA
AVQ18912.1\|1461415_1461802_+	hypothetical protein	A0A067ZI88	Vibrio_phage	2.2e-14	34.4
AVQ18913.1\|1461801_1462119_+	hypothetical protein	A0A0E3Y6F8	Fusobacterium_phage	3.3e-16	49.1
AVQ18914.1\|1462111_1463209_+\|plate	baseplate J protein	A0A0E3U2P1	Fusobacterium_phage	1.4e-114	58.0
AVQ18915.1\|1463201_1463777_+\|tail	phage tail protein I	A0A0E3U255	Fusobacterium_phage	1.2e-37	48.8
AVQ18916.1\|1463837_1466021_+	hypothetical protein	A0A0E3Y5F3	Fusobacterium_phage	9.9e-35	45.2
AVQ18917.1\|1466017_1466215_-	hypothetical protein	NA	NA	NA	NA
AVQ20076.1\|1466616_1466868_-	hypothetical protein	NA	NA	NA	NA
AVQ18918.1\|1467237_1467432_+	hypothetical protein	NA	NA	NA	NA
AVQ18919.1\|1467428_1467653_-	hypothetical protein	NA	NA	NA	NA
AVQ18920.1\|1468003_1468963_+\|integrase	integrase	A0A0E3U2P3	Fusobacterium_phage	7.3e-75	45.9
AVQ18921.1\|1469211_1469745_+	hypothetical protein	NA	NA	NA	NA
1469280:1469295	attR	NA	NA	NA	NA
AVQ18922.1\|1469918_1470341_+	hypothetical protein	A0A0R6PID9	Moraxella_phage	4.4e-16	39.6
AVQ18923.1\|1470364_1470619_+	hypothetical protein	NA	NA	NA	NA
AVQ18924.1\|1470634_1471102_+\|holin	holin	M9Q253	Clostridium_phage	6.0e-14	37.9

DBSCAN-SWA_3

1920044 : 1924745

uncultured_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ19322.1\|1920044_1921634_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.5e-157	54.0
AVQ19323.1\|1921879_1922308_+	6-carboxytetrahydropterin synthase	J9PV91	Bacillus_phage	5.3e-09	31.9
AVQ19324.1\|1922307_1922976_+	7-carboxy-7-deazaguanine synthase QueE	S4TZT1	uncultured_phage	3.1e-40	45.5
AVQ19325.1\|1922975_1923551_+	GTP cyclohydrolase I FolE	S4U0J3	uncultured_phage	1.0e-47	52.1
AVQ19326.1\|1923563_1924262_+	7-cyano-7-deazaguanine synthase QueC	A0A1U9WRB5	Streptococcus_virus	2.2e-60	51.6
AVQ19327.1\|1924262_1924745_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	2.8e-51	72.9

DBSCAN-SWA_4

1968316 : 1999798

Fusobacterium_phage(30.77%)

terminase,integrase,tail,protease,holin,head

attL 1987830:1987846|attR 2001500:2001516

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ19374.1\|1968316_1968979_+	hypothetical protein	A6M984	Geobacillus_virus	6.1e-20	31.7
AVQ19375.1\|1968978_1969974_+	hypothetical protein	M9Q2G6	Clostridium_phage	1.8e-20	44.7
AVQ19376.1\|1969984_1970260_+	hypothetical protein	NA	NA	NA	NA
AVQ19377.1\|1970260_1970512_+	hypothetical protein	NA	NA	NA	NA
AVQ19378.1\|1970640_1971039_+	hypothetical protein	NA	NA	NA	NA
AVQ20101.1\|1971077_1971779_+	site-specific DNA-methyltransferase	X2KMD0	Enterococcus_phage	1.1e-56	46.8
AVQ19379.1\|1971902_1972256_+	VRR-NUC domain-containing protein	NA	NA	NA	NA
AVQ19380.1\|1972280_1972580_+	hypothetical protein	NA	NA	NA	NA
AVQ19381.1\|1972576_1972792_+	hypothetical protein	NA	NA	NA	NA
AVQ19382.1\|1973245_1973425_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A0A8WHQ4	Clostridium_phage	2.1e-07	47.2
AVQ19383.1\|1973564_1974113_+	chromosome partitioning protein ParB	A0A0E3U266	Fusobacterium_phage	1.0e-41	56.7
AVQ19384.1\|1974105_1974903_+	hypothetical protein	A0A142IE79	Pseudomonas_phage	4.0e-18	31.5
AVQ19385.1\|1974918_1975575_+	DUF1804 domain-containing protein	NA	NA	NA	NA
AVQ19386.1\|1975574_1976915_+\|terminase	PBSX family phage terminase large subunit	A0A0E3Y6C0	Fusobacterium_phage	1.8e-63	36.8
AVQ19387.1\|1976895_1979076_+\|head	phage head morphogenesis protein	U5PW71	Bacillus_virus	7.4e-06	29.6
AVQ19388.1\|1979082_1979631_+	phage virion morphogenesis protein	NA	NA	NA	NA
AVQ19389.1\|1979791_1980769_+	hypothetical protein	NA	NA	NA	NA
AVQ19390.1\|1980782_1981151_+	hypothetical protein	NA	NA	NA	NA
AVQ19391.1\|1981154_1982138_+	hypothetical protein	NA	NA	NA	NA
AVQ19392.1\|1982183_1982579_+	hypothetical protein	NA	NA	NA	NA
AVQ19393.1\|1982571_1982997_+	hypothetical protein	NA	NA	NA	NA
AVQ19394.1\|1983009_1983525_+	hypothetical protein	NA	NA	NA	NA
AVQ19395.1\|1983591_1984218_+	hypothetical protein	NA	NA	NA	NA
AVQ19396.1\|1984214_1986902_+\|tail	phage tail tape measure protein	A0A0U4IIN6	Exiguobacterium_phage	3.0e-33	34.4
AVQ19397.1\|1986958_1987369_+	hypothetical protein	NA	NA	NA	NA
AVQ19398.1\|1987365_1988943_+	hypothetical protein	NA	NA	NA	NA
1987830:1987846	attL	NA	NA	NA	NA
AVQ19399.1\|1988939_1989857_+	hypothetical protein	NA	NA	NA	NA
AVQ19400.1\|1989866_1990907_+	hypothetical protein	NA	NA	NA	NA
AVQ19401.1\|1990946_1991306_+	hypothetical protein	NA	NA	NA	NA
AVQ19402.1\|1991348_1991636_+	hypothetical protein	NA	NA	NA	NA
AVQ19403.1\|1991741_1992029_-	hypothetical protein	NA	NA	NA	NA
AVQ19404.1\|1992082_1993069_+\|integrase	integrase	A0A0E3U2P3	Fusobacterium_phage	5.4e-65	39.4
AVQ19405.1\|1993684_1994677_+	hypothetical protein	A0A0E3U258	Fusobacterium_phage	1.0e-18	29.7
AVQ19406.1\|1994776_1995181_+	M15 family peptidase	A0A2K8GPS6	Shigella_phage	3.2e-24	44.4
AVQ20102.1\|1995194_1995440_+	hypothetical protein	NA	NA	NA	NA
AVQ19407.1\|1995450_1995900_+\|holin	holin	M9Q253	Clostridium_phage	8.9e-15	38.8
AVQ19408.1\|1996096_1996300_+	hypothetical protein	NA	NA	NA	NA
AVQ19409.1\|1996530_1997577_+	AAA family ATPase	NA	NA	NA	NA
AVQ19410.1\|1997569_1999798_+\|protease	serine protease	NA	NA	NA	NA
2001500:2001516	attR	NA	NA	NA	NA

DBSCAN-SWA_5

2287665 : 2293701

Prochlorococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ19673.1\|2287665_2289168_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH	Q58MG4	Prochlorococcus_phage	6.7e-67	46.7
AVQ19674.1\|2289182_2289761_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.1e-23	36.9
AVQ19675.1\|2289748_2290750_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FC27	Synechococcus_phage	1.3e-66	45.2
AVQ20119.1\|2290777_2292175_-	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	1.2e-57	33.6
AVQ19676.1\|2292177_2292891_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	5.1e-41	42.8
AVQ19677.1\|2293221_2293701_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.7e-27	46.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage