CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP028103	Fusobacterium varium ATCC 27725 chromosome, complete genome	0 crisprs	DEDDh,csm6,cas3,WYL,csa3,cas4,cas6,cas8b1,cas7b,cas5,cas1,cas2,DinG	0	0	3	0
CP028104	Fusobacterium varium ATCC 27725 plasmid pFvar_27725, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

673548 : 681314

Staphylococcus_phage(57.14%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ30257.1\|673548_674262_-	ribonuclease HII	E3T5H8	Cafeteria_roenbergensis_virus	7.4e-32	45.7
AVQ30258.1\|674275_675217_-	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	8.6e-12	33.1
AVQ30259.1\|675331_676525_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.2e-116	54.2
AVQ30260.1\|676542_677199_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	3.4e-31	37.6
AVQ32530.1\|677207_678269_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.0e-50	34.7
AVQ32531.1\|678286_678748_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.1e-41	55.7
AVQ30261.1\|679131_680463_+	MATE family efflux transporter	NA	NA	NA	NA
AVQ30262.1\|680480_681314_+	peptidase M23	I2E8W3	Clostridium_phage	1.0e-19	54.3

DBSCAN-SWA_2

745888 : 824928

Clostridium_phage(38.46%)

integrase,portal,capsid,protease,terminase,holin,tail

attL 767933:767950|attR 789799:789816

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ30316.1\|745888_746329_-\|holin	holin	A0A0E3Y658	Fusobacterium_phage	5.2e-28	55.5
AVQ30317.1\|746344_746833_-	hypothetical protein	NA	NA	NA	NA
AVQ30318.1\|746847_747270_-	hypothetical protein	NA	NA	NA	NA
AVQ30319.1\|747314_747842_-	hypothetical protein	NA	NA	NA	NA
AVQ30320.1\|748113_749073_-\|integrase	integrase	A0A0E3U2P3	Fusobacterium_phage	1.2e-74	45.3
AVQ30321.1\|749213_749456_+	hypothetical protein	NA	NA	NA	NA
AVQ30322.1\|749472_750471_-	hypothetical protein	NA	NA	NA	NA
AVQ30323.1\|750460_751111_-	DUF2313 domain-containing protein	NA	NA	NA	NA
AVQ30324.1\|751088_752168_-\|tail	phage tail protein	X5JAB8	Clostridium_phage	3.6e-78	46.1
AVQ30325.1\|752160_752586_-	DUF2634 domain-containing protein	A0A0A8WFW6	Clostridium_phage	1.5e-24	49.2
AVQ30326.1\|752582_753023_-	DUF2577 domain-containing protein	S5MC71	Brevibacillus_phage	5.1e-07	31.1
AVQ32536.1\|753015_753975_-	hydrolase	H7BVH4	unidentified_phage	4.6e-77	48.7
AVQ30327.1\|753994_754651_-	LysM domain-containing protein	A0A0A8WFE5	Clostridium_phage	3.1e-32	40.7
AVQ30328.1\|754653_756774_-	hypothetical protein	X5JAB7	Clostridium_phage	3.6e-66	29.9
AVQ30329.1\|756971_757382_-\|portal	phage portal protein	Q708L8	Streptococcus_phage	1.3e-09	35.2
AVQ30330.1\|757394_757871_-	hypothetical protein	A0A0A8WJ62	Clostridium_phage	2.1e-43	56.5
AVQ30331.1\|757888_759202_-\|tail	phage tail protein	X5JAJ1	Clostridium_phage	1.7e-130	52.2
AVQ30332.1\|759202_759388_-	hypothetical protein	NA	NA	NA	NA
AVQ30333.1\|759400_759841_-	hypothetical protein	NA	NA	NA	NA
AVQ30334.1\|759837_760386_-	hypothetical protein	A0A0A7RTT0	Clostridium_phage	9.8e-24	36.8
AVQ30335.1\|760385_760769_-	hypothetical protein	A0A0A7RTV0	Clostridium_phage	1.2e-15	41.5
AVQ30336.1\|760765_761167_-	hypothetical protein	NA	NA	NA	NA
AVQ30337.1\|761176_761545_-	hypothetical protein	NA	NA	NA	NA
AVQ30338.1\|761558_762512_-\|capsid	phage capsid protein	A0A1J0MCK3	Streptomyces_phage	2.6e-80	52.4
AVQ30339.1\|762525_763119_-	hypothetical protein	Q5YA71	Bacillus_phage	4.9e-05	47.9
AVQ30340.1\|763385_763649_-	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	1.4e-28	66.7
AVQ30341.1\|763704_763890_-	hypothetical protein	NA	NA	NA	NA
AVQ30342.1\|763886_765620_-	hypothetical protein	A0A0A8WIE7	Clostridium_phage	3.3e-110	56.4
AVQ30343.1\|765603_767037_-\|portal	phage portal protein	A0A0A7S074	Clostridium_phage	1.4e-82	38.8
AVQ30344.1\|767055_768462_-\|terminase	terminase	A0A090EUA8	Clostridium_phage	1.1e-193	73.5
767933:767950	attL	NA	NA	NA	NA
AVQ30345.1\|768448_768970_-\|terminase	terminase small subunit	A0A0A0RSW5	Bacillus_phage	1.8e-19	34.2
AVQ30346.1\|769036_769846_-\|protease	serine protease	A0A2H4JE36	uncultured_Caudovirales_phage	7.4e-36	38.4
AVQ30347.1\|769990_770416_-	DUF1492 domain-containing protein	NA	NA	NA	NA
AVQ30348.1\|770431_771115_-	hypothetical protein	NA	NA	NA	NA
AVQ30349.1\|771117_772491_-	ATP-dependent helicase	S5MA26	Brevibacillus_phage	1.1e-145	55.4
AVQ30350.1\|772506_772800_-	VRR-NUC domain-containing protein	Q3LZN4	Bacteriophage	8.0e-17	56.2
AVQ30351.1\|773152_775546_-	virulence-associated protein E	A0A0A7RTG3	Clostridium_phage	6.5e-205	46.5
AVQ30352.1\|775563_775836_-	hypothetical protein	A0A0A7RWV6	Clostridium_phage	1.7e-21	54.4
AVQ30353.1\|775846_777820_-	DNA polymerase I	H7BVQ1	unidentified_phage	2.4e-221	58.4
AVQ32537.1\|778000_778570_-	DUF2815 domain-containing protein	W8CPL2	Croceibacter_phage	4.7e-37	45.8
AVQ30354.1\|778579_779737_-	DUF2800 domain-containing protein	A0A0A7S066	Clostridium_phage	3.9e-99	48.7
AVQ30355.1\|779736_780138_-	hypothetical protein	NA	NA	NA	NA
AVQ30356.1\|780150_780408_-	hypothetical protein	NA	NA	NA	NA
AVQ30357.1\|780408_780588_-	hypothetical protein	NA	NA	NA	NA
AVQ30358.1\|780677_780878_-	hypothetical protein	A0A0S2MV91	Bacillus_phage	2.3e-07	60.5
AVQ30359.1\|781065_781464_-	hypothetical protein	NA	NA	NA	NA
AVQ30360.1\|781485_781770_-	hypothetical protein	NA	NA	NA	NA
AVQ30361.1\|781787_782105_-	hypothetical protein	NA	NA	NA	NA
AVQ30362.1\|782104_782329_-	hypothetical protein	NA	NA	NA	NA
AVQ30363.1\|782344_782695_-	hypothetical protein	NA	NA	NA	NA
AVQ30364.1\|782691_782895_-	hypothetical protein	NA	NA	NA	NA
AVQ30365.1\|782884_783109_-	hypothetical protein	NA	NA	NA	NA
AVQ30366.1\|783159_783372_-	XRE family transcriptional regulator	A0A1W6JNS4	Staphylococcus_phage	1.3e-05	40.0
AVQ30367.1\|783516_783951_+	XRE family transcriptional regulator	A0A0S2SXM8	Bacillus_phage	4.6e-08	31.1
AVQ30368.1\|783962_784382_+	ImmA/IrrE family metallo-endopeptidase	S6B1N5	Thermus_phage	3.1e-14	36.8
AVQ30369.1\|784565_785639_+\|integrase	site-specific integrase	A0A0A8WF08	Clostridium_phage	1.4e-69	43.1
AVQ30370.1\|786399_786951_-	hypothetical protein	NA	NA	NA	NA
AVQ30371.1\|787219_788104_+	rubrerythrin family protein	NA	NA	NA	NA
AVQ30372.1\|788293_789241_+	succinylglutamate desuccinylase	NA	NA	NA	NA
AVQ30373.1\|789373_789844_+	hypothetical protein	NA	NA	NA	NA
789799:789816	attR	NA	NA	NA	NA
AVQ30374.1\|790251_790812_+	hypothetical protein	NA	NA	NA	NA
AVQ30375.1\|790825_800554_+	autotransporter-associated N-terminal domain-containing protein	NA	NA	NA	NA
AVQ30376.1\|800619_800817_+	hypothetical protein	NA	NA	NA	NA
AVQ30377.1\|800856_801279_+	hypothetical protein	NA	NA	NA	NA
AVQ30378.1\|801356_801629_-	hypothetical protein	NA	NA	NA	NA
AVQ30379.1\|802985_803279_-	GIY-YIG nuclease family protein	A0A1S5YDY6	Mythimna_unipuncta_granulovirus	4.9e-06	37.5
AVQ30380.1\|803491_804832_+	DUF1576 domain-containing protein	NA	NA	NA	NA
AVQ30381.1\|804868_805387_+	NUDIX hydrolase	NA	NA	NA	NA
AVQ30382.1\|805499_807206_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.7e-61	32.0
AVQ30383.1\|807395_808289_-	GTPase Era	NA	NA	NA	NA
AVQ30384.1\|808292_809078_-	hypothetical protein	NA	NA	NA	NA
AVQ30385.1\|809080_810745_-	DNA repair protein RecN	NA	NA	NA	NA
AVQ30386.1\|810738_811542_-	NAD(+) kinase	NA	NA	NA	NA
AVQ30387.1\|811560_812658_-	peptidase M23	NA	NA	NA	NA
AVQ30388.1\|812654_813503_-	cell division protein FtsX	NA	NA	NA	NA
AVQ30389.1\|813591_814521_-	transketolase family protein	NA	NA	NA	NA
AVQ30390.1\|814553_815372_-	transketolase	NA	NA	NA	NA
AVQ30391.1\|815456_816050_-	hypothetical protein	NA	NA	NA	NA
AVQ30392.1\|816135_817320_-	elongation factor Tu	A0A2K9KZ60	Tupanvirus	2.0e-13	27.1
AVQ30393.1\|817411_819493_-	elongation factor G	E4ZFJ7	Streptococcus_phage	6.9e-62	27.1
AVQ30394.1\|819550_820021_-	30S ribosomal protein S7	NA	NA	NA	NA
AVQ30395.1\|820045_820414_-	30S ribosomal protein S12	NA	NA	NA	NA
AVQ30396.1\|820551_822459_-	ABC transporter ATP-binding protein	A0A2K9L0W2	Tupanvirus	4.3e-58	31.8
AVQ30397.1\|822621_824928_+\|protease	serine protease	A0A2H4UUE4	Bodo_saltans_virus	2.9e-16	35.8

DBSCAN-SWA_3

2813359 : 2819118

Prochlorococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ32094.1\|2813359_2814862_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH	Q58MG4	Prochlorococcus_phage	4.2e-69	48.3
AVQ32095.1\|2814878_2815454_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	4.3e-22	39.1
AVQ32096.1\|2815441_2816443_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SQF5	Cyanophage	1.9e-65	44.2
AVQ32097.1\|2816464_2817862_-	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	3.3e-60	35.0
AVQ32098.1\|2817861_2818578_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	3.6e-42	44.1
AVQ32099.1\|2818638_2819118_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	9.7e-28	48.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage