CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP020664	Microcystis sp. MC19 chromosome, complete genome	12 crisprs	cas14k,cas10,cmr3gr5,cmr4gr7,cmr5gr11,csm3gr7,cas14j,WYL,Cas14c_CAS-V-F,c2c9_V-U4,csa3,cas3,RT,cas1,DinG,2OG_CAS	8	12	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP020664_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020664_1

197668-197766

Orphan

Consensus_repeat	Method
GGCAATTCGCCCCTACGGTGGGGAAAATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020664_1

>merge|CP020664|1|197668-197766|CRISPRCasFinder
GGCAATTCGCCCCTACGGTGGGGAAAATTCGTATTCTGTAGGGGCGTACCGCGTACGCCCTCCCCTCGAGGGCAATTCGCCCCTACGGTGGGAAAAATT

>CP020664|1|1|197668-197766|CRISPRCasFinder
GGCAATTCGCCCCTACGGTGGGGAAAATT	CGTATTCTGTAGGGGCGTACCGCGTACGCCCTCCCCTCGAG
GGCAATTCGCCCCTACGGTGGGAAAAATT

Protein	Signature genes	Signature genes Name	Protein_function
CP020664.1\|AVQ70074.1\|189352_189898_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238089
CP020664.1\|AVQ70089.1\|206666_206849_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ70073.1\|188240_189137_-\|permease	unknown	unknown	gnl\|CDD\|376667
CP020664.1\|AVQ70079.1\|193399_193609_-\|thiamine-biosynthesis-protein-ThiS	unknown	unknown	gnl\|CDD\|180978
CP020664.1\|AVQ70077.1\|191462_192233_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372807
CP020664.1\|AVQ74180.1\|197876_198512_+\|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase	unknown	unknown	gnl\|CDD\|235067
CP020664.1\|AVQ70086.1\|202652_203534_-\|tRNA-pseudouridine(55)-synthase-TruB	unknown	unknown	gnl\|CDD\|179469
CP020664.1\|AVQ70084.1\|198923_200309_+\|mercuric-reductase	unknown	unknown	gnl\|CDD\|224169
CP020664.1\|AVQ70080.1\|193870_194887_-\|thiamine-phosphate-diphosphorylase	unknown	unknown	gnl\|CDD\|235054
CP020664.1\|AVQ70075.1\|189920_190622_-\|Zn-dependent-hydrolase	unknown	unknown	gnl\|CDD\|293810
CP020664.1\|AVQ70081.1\|195115_195727_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239738
CP020664.1\|AVQ70090.1\|206849_207266_-\|response-regulator	unknown	unknown	gnl\|CDD\|381090
CP020664.1\|AVQ70076.1\|190832_191126_-\|ferredoxin	unknown	unknown	gnl\|CDD\|273926
CP020664.1\|AVQ70088.1\|204807_206379_-\|5-oxoprolinase	unknown	unknown	gnl\|CDD\|223224
CP020664.1\|AVQ70087.1\|203639_204686_-\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	unknown	unknown	gnl\|CDD\|236585
CP020664.1\|AVQ70091.1\|208107_208689_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370453
CP020664.1\|AVQ70078.1\|192229_193366_-\|anhydro-N-acetylmuramic-acid-kinase	unknown	unknown	gnl\|CDD\|236579
CP020664.1\|AVQ70082.1\|196845_197487_+\|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	gnl\|CDD\|131644
CP020664.1\|AVQ70083.1\|198675_198870_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ70085.1\|200963_202457_+\|thymidylate-synthase	unknown	unknown	gnl\|CDD\|179181

Protein	Function_ID	Function_description	E-value
CP020664.1\|AVQ70074.1\|189352_189898_-\|hypothetical-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	7.86555e-28
CP020664.1\|AVQ70073.1\|188240_189137_-\|permease	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	6.87294e-37
CP020664.1\|AVQ70079.1\|193399_193609_-\|thiamine-biosynthesis-protein-ThiS	gnl\|CDD\|180978	PRK07440, PRK07440, thiamine biosynthesis protein ThiS.	1.84582e-36
CP020664.1\|AVQ70077.1\|191462_192233_-\|hypothetical-protein	gnl\|CDD\|372807	pfam13911, AhpC-TSA_2, AhpC/TSA antioxidant enzyme. This family contains proteins related to alkyl hydro-peroxide reductase (AhpC) and thiol specific antioxidant (TSA).	2.56254e-13
CP020664.1\|AVQ74180.1\|197876_198512_+\|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase	gnl\|CDD\|235067	PRK02759, PRK02759, bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE.	3.62123e-128
CP020664.1\|AVQ70086.1\|202652_203534_-\|tRNA-pseudouridine(55)-synthase-TruB	gnl\|CDD\|179469	PRK02755, truB, tRNA pseudouridine synthase B; Provisional.	4.75424e-144
CP020664.1\|AVQ70084.1\|198923_200309_+\|mercuric-reductase	gnl\|CDD\|224169	COG1249, Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion].	1.4278e-65
CP020664.1\|AVQ70080.1\|193870_194887_-\|thiamine-phosphate-diphosphorylase	gnl\|CDD\|235054	PRK02615, PRK02615, thiamine phosphate synthase.	0
CP020664.1\|AVQ70075.1\|189920_190622_-\|Zn-dependent-hydrolase	gnl\|CDD\|293810	cd07724, POD-like_MBL-fold, ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain. Persulfide dioxygenase (PDO, also known as sulfur dioxygenase, SDO, EC 1.13.11.18) is a non-heme iron-dependent oxygenase which catalyzes the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria. Mutations in ethe1 (the human PDO gene) are responsible for a rare autosomal recessive metabolic disorder called ethylmalonic encephalopathy. Arabidopsis thaliana ETHE1 is essential for embryo and endosperm development. Bacterial ETHE1-type PDOs are also called Type 1 PDOs. Type II PDOs (also called PDOAs), are mainly proteobacterial. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	5.28168e-87
CP020664.1\|AVQ70081.1\|195115_195727_-\|hypothetical-protein	gnl\|CDD\|239738	cd03769, SR_IS607_transposase_like, Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subfamily is composed of proteins that catalyze the transposition of insertion sequence (IS) elements such as IS607 from Helicobacter and IS1535 from Mycobacterium, and similar proteins from other bacteria and several archaeal species. IS elements are DNA segments that move to new sites in prokaryotic and eukaryotic genomes causing insertion mutations and gene rearrangements.	5.34382e-29
CP020664.1\|AVQ70090.1\|206849_207266_-\|response-regulator	gnl\|CDD\|381090	cd17535, REC_NarL-like, phosphoacceptor receiver (REC) domain of NarL (Nitrate/Nitrite response regulator L) family response regulators. The NarL family is one of the more abundant families of DNA-binding response regulators (RRs). Members of the NarL family contain a REC domain and a helix-turn-helix (HTH) DNA-binding output domain, with a majority of members containing a LuxR-type HTH domain. They function as transcriptional regulators. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.81077e-25
CP020664.1\|AVQ70076.1\|190832_191126_-\|ferredoxin	gnl\|CDD\|273926	TIGR02008, Ferredoxin_root_R-B1, ferredoxin [2Fe-2S]. This model represents single domain 2Fe-2S (also called plant type) ferredoxins. In general, these occur as a single domain proteins or with a chloroplast transit peptide. Species tend to be photosynthetic, but several forms may occur in one species and individually may not be associated with photocynthesis. Halobacterial forms differ somewhat in architecture; they score between trusted and noise cutoffs. Sequences scoring below the noise cutoff tend to be ferredoxin-related domains of larger proteins.	2.8252e-53
CP020664.1\|AVQ70088.1\|204807_206379_-\|5-oxoprolinase	gnl\|CDD\|223224	COG0146, HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	0
CP020664.1\|AVQ70087.1\|203639_204686_-\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	gnl\|CDD\|236585	PRK09604, PRK09604, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD.	0
CP020664.1\|AVQ70091.1\|208107_208689_+\|hypothetical-protein	gnl\|CDD\|370453	pfam09366, DUF1997, Protein of unknown function (DUF1997). This family of proteins are functionally uncharacterized.	9.58563e-68
CP020664.1\|AVQ70078.1\|192229_193366_-\|anhydro-N-acetylmuramic-acid-kinase	gnl\|CDD\|236579	PRK09585, anmK, anhydro-N-acetylmuramic acid kinase; Reviewed.	0
CP020664.1\|AVQ70082.1\|196845_197487_+\|PEP-CTERM-sorting-domain-containing-protein	gnl\|CDD\|131644	TIGR02595, conserved_hypothetical_protein, PEP-CTERM protein-sorting domain. This model describes a 25-residue domain that includes a near-invariant Pro-Glu-Pro (PEP) motif, a thirteen residue strongly hydrophobic sequence likely to span the membrane, and a five-residue strongly basic motif that often contains four Arg residues. In nearly every case, this motif is found within nine residues, and usually within five residues, of the extreme C-terminus of the protein. Proteins with this motif typically have signal sequences at the N-terminus. This region appears many times per genome or not at all, and co-occurs in genomes with a proposed protein-sorting integral membrane protein we designate exosortase (see TIGR02602). PEP-CTERM proteins frequently are poorly conserved, Ser/Thr-rich proteins and may become extensively modified proteinaceous constituents of extracellular material in bacterial biofilms. [Cell envelope, Surface structures].	0.00106475
CP020664.1\|AVQ70085.1\|200963_202457_+\|thymidylate-synthase	gnl\|CDD\|179181	PRK00956, thyA, thymidylate synthase; Provisional.	4.99313e-42

>CP020664.1|AVQ70082.1|196845_197487_+|PEP-CTERM-sorting-domain-containing-protein
MMTTNKLTKTFASGSLAIGVLAGAVLTATSASAAMLSWADWTSGTPLIEGDKKVTFVSGTIGAEAVDDVALMGMGDHYYFVYDAMNGPAMANVNSGSFTYTIEVIGSPDYIVGVDLDSNVTSNYGTVTETFVEVPNVLVSTNGSPVPASGFIPIAPKKLLTVTNTLNNTGGATEGLIDFQNSFRQTTVPEPGTILGLLAVGGLGLVSRFNKQK
>CP020664.1|AVQ70081.1|195115_195727_-|hypothetical-protein
MNTLITIREASDLLGVSIKTLRRWEQQGKIASIRTRGGHRRFRPEDLLQSGQATPLIIGYARVNRPEQKPQLDTQIKALESFCRQQGQPFEILTDIGNGVSHNHPNFMRLVAMICQGEVKCLVLTHAETVSRFCHDFILGLCSLLNVQVIILNQPHESIADADLVEDIQSLVTICYNSLYPIHDQAHQQLLEHLGALKNIRVG
>CP020664.1|AVQ70080.1|193870_194887_-|thiamine-phosphate-diphosphorylase
MKLETTAIKRIIDANLDRAREGLRIIEEWCRFGLDNPDLAQECKEMRHQLASWHSIDLKLHRDTAGDIGRDLSHPREEIRETVEGLLQANLARVQEALRVLEEYGKLYDLELGIACKQLRYRVYQLESKLLISPPLEKLKASPLYLVTSPAENLLEIVELALKGGLKLVQYRHKTAADTIRLEEAAKLCELCHRYDALFIMNDRVDIAQAIHADGVHLGQQDVPVSLARQFLGPTAIIGRSTTNPQEMAKAIQEKADYVGVGPVYATPTKAGKTPAGLEYVRYARENCPLPWFAIGGIDSSNIKEVLEAGAQQVAVVRAIMEAQHPDVVTQELLTQLK
>CP020664.1|AVQ70079.1|193399_193609_-|thiamine-biosynthesis-protein-ThiS
MSEITLQINGKTQTCLPATKLPQMLENLGMNPRLVAVEYNGEILHRQYWENTEIKEGDKLEIVTIVGGG
>CP020664.1|AVQ70078.1|192229_193366_-|anhydro-N-acetylmuramic-acid-kinase
MLVIGLMSGTSVDGIDTALVEISGTVESPQVQFLAGETYPYSPRLRETILQVCGGEKLSIEALASLDDDIAAEFAQAALNIQKEAPKAQLIGSHGQTVFHRPPENDRLGYTVQLGRGAAIAKITSIPTISNFRAADIAQAGHGAPLVPKIDAYLLSHPTKTRCVQNIGGIANLTYLPPRQRENWQQKIFGWDTGPGNVLIDLAVQFLSQGQQTYDHNGQWSAQGQPCSELVHKWLQEPYFQQYPPKSTGRELFSPAYLAQLHRDAQAYCLSHADWLASLTDLTAISIAHSYQTFLPEMPAEVLLCGGGARNAYLRQRLLAHLGSNVKLLTTDEVGLNSDFKEAIAFALLAYWRWHDFPGNLPQVTGAKAAVLLGEIYL
>CP020664.1|AVQ70077.1|191462_192233_-|hypothetical-protein
MSSIYEIFSTIQRQRVSDGQIVPILSDCTDYKRLLILVWPQLGDFDSLEYAWWLEKEAALWQNAGISIRAIGIGDRNSGLKFAEYTKFRQDWLFVDPKAELHNLLGLYRGLSLKLPRFSPGQNAWLNLILMCAGLGSPGTLAEVLRGYLGDRKAPQLIAEEETMQARPLPPFRGSLFNLAGGEGFQRPFELATLRLRNMGQVLGNWSTYIPDSSYLTQRGGTFLFDSQGNLLYEHRDRAILGFAENMSYPLAFLRD
>CP020664.1|AVQ70076.1|190832_191126_-|ferredoxin
MATYKVTLKTPGGEQTIDVPDDEYILDIAEEKGLALPSSCRAGACSSCAGKIESGSVNQSEQSFLDADQIEAGYVLTCVAYPTSDCVIVTHKEEDLY
>CP020664.1|AVQ70075.1|189920_190622_-|Zn-dependent-hydrolase
MLFRQMFDPETSTYTYLIADPVSKEAVLVDPVREQVERDDRQLRELGLTLKYCLETHIHADHVTGTGKLRQITGCLGIVPENAQVACADRHLAGGEELLLGNITIKAIATPGHTDSHLAYLVNNSHILTGDALFIRGCGRTDFQSGDAGTLFDSVTQKLFTLPDSTLVYPGHDYRGLTVSTIAEEKQYNPRFVGRNRRQFIEFMNSLNLPDPKKIMEAVPANQGCGNLGVVLT
>CP020664.1|AVQ70074.1|189352_189898_-|hypothetical-protein
MTHTTNQAKLLEFDAHTLKNLIERREVCLIDVREPGEYASDRIPGAKLVPLSSFNPNSIAFDPNQTLVLYCNSGSRSTVAAQKLIAAGFSQVAQLKNGLNTWKSAGYATEKDQNAPISLFRQVQIVAGSLVVLGTVLGAFLSPWFLILSGFVGSGLVFAGISNTCALAMLLAKLPYNQPHQ
>CP020664.1|AVQ70073.1|188240_189137_-|permease
MTWLIGHLLAVCTGISLGLLGGGGSVLALPILVYVMGVPTKSAIAMTLLVIGSVSLLGTIPHWKKGNINLKTAFIFGSATMIGAFLGARLATLPFVTATFQMLLFATLMLLAAAFMISRSTQIDNPDYKARDRQKNLTLYPQPVCRYCWLWLMSEGIAVGVLTGLVGVGGGFAIVPALVLLGKIPMVQAIATSLLIIFLNSVAGLLGYLGHISVDWQLTLSFAFAAALGTLIGSYLGHFVSAKQLQKGFGYFLLAIATLVLIQNRHILHNFLTPKGNSIIPAEKVRFIQPTLLKTDNG
>CP020664.1|AVQ74180.1|197876_198512_+|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase
MSSLLSAIPLDAIAYNPQGLVPAIAQDYLDATVLMMAWMNRESLEKTLTTGEAWYWSRSRQELWHKGATSGHIQKVRQIRYDCDSDAILLTIEQIGDIACHTGERSCFHQVNSQKSPPAADTLSELFKVICDRRDEPHPESYTCKLLAGGDNKILKKIGEESAEVVMACKDNDGDAIASEVADLFYHTLVALAYHQVPLRDVYKKLQDRRR
>CP020664.1|AVQ70083.1|198675_198870_+|hypothetical-protein
MPPYLSVKFPIPEYRLLTPDLKEGVGCRVWGVGGWGNGETTSCALRGEVGKWGSGGISTKTLKP
>CP020664.1|AVQ70084.1|198923_200309_+|mercuric-reductase
MVYDLVIIGATPAGIEAALLAVHLKKRVALVQQPSRDNLEASEDIFSKGYSQIIHLYKLLNHWQETAIYPQWQRLRQWLEEVDKTINKYHSLARLATEGIDVILGGGEFVRLPHLGFVVNGRQLLAKHYLIAPDFSPQVPKIFGLDDVNYFTAQTLWQEPNLDKLGQHLGIIGNSSMAVSLAQILRRLGKEISLIIEDSYLLPDIDQEISSLVTAILEAEGIKILPGYCPSQVKAIEGQKWLQLGNRVIEVDDLIFAGNYQVNEQGLNLVGVGVKLEQGLIKVNQQLQTDNSRIYALNLLRNNYPDPTLNHRAAFGLVKHLLTGEKFNFNPDQIPSFIAFDPAIAWVGLTGKADQDSYGEQVKMINYPIKNMVSQQIWGETTGFCQLIYRQDGKILGAQIVGNQAAEMISIISLALQENLTIQSLNKNIYAWGSMGEIIGEMTELIPQKKSWLTWLKKLFR
>CP020664.1|AVQ70085.1|200963_202457_+|thymidylate-synthase
MLSTETTPKFIYQPHYKPNQLICGHGQTAIITGWTVKQSLAKHLNTDQYAVIGNLYSPTRGISPLLRNLIANPHVRYLVILNATKEDKNSGSCQCLLDFFSQGFQSGKSDTGRECWLINSSITGYIDKEIDRETLEKLRQSIQYQMVKSIPEAIETVKNYAEQSPLPTWGEPLIFPLLENLPSLLPGTRYGHRIEGKTIAETWVKILQKIKTTGTIRPTGYDGKWQELIDLMAVVTNEPSDFYFPEPNYLPIDRAFLTEYIGQILDDSPIHQGVKYTYGQRLRSWFGRDQIAQVINKLISEIDAASAVMSLWDVKDHEKGGSPCLNHIWVRVVENELSLTAIFRSNDMFAAWPANAMGLRALQQHIRDEISKRSDYNLSMGPLITISQSAHIYDDTWENVERLIATQYDKIVNQRDFFDPSGNFLISVEKEQILLQQTTPGSGEIVACYQGKNPLKLIRELAATNPAIIPEHIGYLGIELQKAYNCLKNNQPYIQDQ
>CP020664.1|AVQ70086.1|202652_203534_-|tRNA-pseudouridine(55)-synthase-TruB
MFGFLNLNKPPDWTSHDCVAKVRKILKTKRVGHGGTLDPMATGVLPIAVGSATRLLPYLPENKAYRAKIQLGLSTDTDDITGKAIATCPCGDLTLEAVKPHLAEFIGNIAQIPPMYSAIHQDGRRLYELARKGEIIAVEPRQVKIDQITVLGWLEGEFPQIELDIDCGSGTYIRSLARDLGKVLAVGGTLASLTRTESCGFQLADSINLEALMANSESLISPRIALAHLDWISLTPEKVIDWFHGRKINLTDTNVMIGSLVAVESLEAQFLGIGEIVVREDEYYLQPKIVIQQ
>CP020664.1|AVQ70087.1|203639_204686_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD
MTIILAIETSCDETAVAIVNHNRVLSSVVSSQIDLHRLYGGVVPEMASRQHLETINFCLEKAWQETGLTWSEIDGIAATVAPGLVGALMVGMTAAKTLAIVHDKPFIGIHHLEGHIYASYLAESDLKPPFLSLLVSGGHTSLIHVQGCGKYQQLGTTRDDAAGEAFDKVARLLNLSYPGGPIIDRMAKDGNPQAFPLPEGKISLPSGGFHAYDSSFSGLKTAVLRLVEKFEPDNLPVADIAASFQDTVARSLTRRTINCALDYGLKTIAIGGGVAANSALRNHLETAAKNHDLTVYFPPLKLCTDNAAMIARAAVDHYDLGHFSDLSLGVRSRLPLSEVMQLYNTSDF
>CP020664.1|AVQ70088.1|204807_206379_-|5-oxoprolinase
MSPLNSHRTEITTVADPIYLEIFKNLYQFIAEEMGITLQNTAASVNIKERLDFSCAIFDEVGNLIANAPHIPVHLGSMADSVKSLIQDKGETIRRGNVYLANNPYNGGTHLPDVTVISPIFDRQNQEILFYLASRGHQADIGGITPGSMPPHSVHISEEGILFDNFLLVAAGQFREQELINHLTNSPFPARNIAQNIADFQAQIAANAKGERELHNMVDRYGLAMVKAYQQFVQDNAELAVRKAISVLKDGEFTYYLDNGAVIKVRITIDIENCQASIDFTGTSNQLNNNFNAPLAVTRAAVLYVFRTLVEEAIPLNAGCFKPLHLIIPSGCFLNPVYPAAVVAGNVETSQAIVNALYGALGIQAASQGTMNNFTFGNQKYQYYETICGGSGAGANFAGTAAVQTQMTNSRLTDPEVLEMRYPVLVESFSIRPDSGGKGQYSGGDGVIRRIKFQESMTANILSGNRQIPPFGLAGGKAGKIGRNVVERNDGTIEELPGTATVEMNPGDIFIIETPGGGGYGNC
>CP020664.1|AVQ70089.1|206666_206849_+|hypothetical-protein
MDKTSLIDKVKQMANKRDYLLQLRDKPDIGGLRLDVNQALEELDELLDEFQATFPEEKLS
>CP020664.1|AVQ70090.1|206849_207266_-|response-regulator
MKPIDLIKVLIADDHDLTCLGLKTLISQQPHCQVVGIAVNGQQAIDLAKSCQPDVIILNIGMPVLDGHSAAIQIKQFDPYIRIIAYSSLPKLPMEKNNQSTAFDLYCSKDISSQALIKAIDDLGKLAQSDKDQFRRVG
>CP020664.1|AVQ70091.1|208107_208689_+|hypothetical-protein
MEVTFTAAESLEIVVAEQTIPIQHYLRQPQRLVQAIVETSLTEHLSEHRFRLKMRPLNFLDLYYFQPTVILNVWATSGGTIFLQSEDCQIKGIDYINDRFSLNVKGKLAPVEKNNQTYLAGKANLEVKVALPPPLWLTPRPLLEITGNSLLKGVLLRIKQRLMSQLLQDYQQWAKQDIIAQNYPETILDLSLS

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Crispr_ID: CP020664_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020664_2

707708-708246

TypeIII

Consensus_repeat	Method
GTTTCCATTCAATTAATTTCTAA	CRISPRCasFinder
GTTTCCATTCAANTAATTTCTAA	CRT

7 spacers

cas10,cmr3gr5,cmr4gr7,cmr5gr11,csm3gr7

The CRISPR arrays of CP020664_2

>merge|CP020664|2|707708-708246|CRISPRCasFinder,CRT
GTTTCCATTCAACTAATTTCTAAGCGCGAGTAGAGAGGCAACTAATAATACTCAATAAAACGCAGCAGTATTGTCGTTTCCATTCAATTAATTTCTAAGCGCGAGTAGAGACTAAAATTATAGGGTAAGGTCTAAGACGATTCTGTTACAAATGTTTCCATTCAATTAATTTCTAACTGCGAGTAGAGAGTAGGGTTAATTCATGAATTAACCCTACAAATGTTTCCATTCAATTAATTTCTAAGCGCGAGTAGAGAGTTCATTAAGAAAAAACACAAACATATTAGGAGTACAGTTTCCATTCAATTAATTTCTAAGTGCGAGTAGAGAGAAAAGCCTCTAAATACCGGTTCGCCCTCGACCTTATCTTTCCATTCAACTAATTTCTAAGCGTAAGCAGAGAGTCGGGCAGTTGAAAACTTGAAGTCGGGAGAATCCATTTGTTTCCATTCAACTAATTTCTTCAGTGAGTATAGAGATGGGGTTAATGTAACATTACTATAAATATCTTGTCAAGTTTCTATTCAATCATCCTATAA

>CP020664|2|2|707708-708246|CRISPRCasFinder
GTTTCCATTCAACTAATTTCTAA	GCGCGAGTAGAGAGGCAACTAATAATACTCAATAAAACGCAGCAGTATTGTC
GTTTCCATTCAATTAATTTCTAA	GCGCGAGTAGAGACTAAAATTATAGGGTAAGGTCTAAGACGATTCTGTTACAAAT
GTTTCCATTCAATTAATTTCTAA	CTGCGAGTAGAGAGTAGGGTTAATTCATGAATTAACCCTACAAAT
GTTTCCATTCAATTAATTTCTAA	GCGCGAGTAGAGAGTTCATTAAGAAAAAACACAAACATATTAGGAGTACA
GTTTCCATTCAATTAATTTCTAA	GTGCGAGTAGAGAGAAAAGCCTCTAAATACCGGTTCGCCCTCGACCTTAT
CTTTCCATTCAACTAATTTCTAA	GCGTAAGCAGAGAGTCGGGCAGTTGAAAACTTGAAGTCGGGAGAATCCATTT
GTTTCCATTCAACTAATTTCTTC	AGTGAGTATAGAGATGGGGTTAATGTAACATTACTATAAATATCTTGTCAA
GTTTCTATTCAATCATCCTATAA

>CP020664|2|1|707708-708172|CRT
GTTTCCATTCAACTAATTTCTAA	GCGCGAGTAGAGAGGCAACTAATAATACTCAATAAAACGCAGCAGTATTGTC
GTTTCCATTCAATTAATTTCTAA	GCGCGAGTAGAGACTAAAATTATAGGGTAAGGTCTAAGACGATTCTGTTACAAAT
GTTTCCATTCAATTAATTTCTAA	CTGCGAGTAGAGAGTAGGGTTAATTCATGAATTAACCCTACAAAT
GTTTCCATTCAATTAATTTCTAA	GCGCGAGTAGAGAGTTCATTAAGAAAAAACACAAACATATTAGGAGTACA
GTTTCCATTCAATTAATTTCTAA	GTGCGAGTAGAGAGAAAAGCCTCTAAATACCGGTTCGCCCTCGACCTTAT
CTTTCCATTCAACTAATTTCTAA	GCGTAAGCAGAGAGTCGGGCAGTTGAAAACTTGAAGTCGGGAGAATCCATTT
GTTTCCATTCAACTAATTTCTTC

Protein	Signature genes	Signature genes Name	Protein_function
CP020664.1\|AVQ70551.1\|712688_713468_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl\|CDD\|274210
CP020664.1\|AVQ70557.1\|719985_720450_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ70556.1\|719330_719630_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ70546.1\|706079_706397_+\|stress-induced-bacterial-acidophilic-repeat-motif-family-protein	unknown	unknown	unknown
CP020664.1\|AVQ70554.1\|718348_718621_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377648
CP020664.1\|AVQ70550.1\|711557_712682_+\|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl\|CDD\|187879
CP020664.1\|AVQ70542.1\|699437_700220_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ70541.1\|698387_699326_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133030
CP020664.1\|AVQ70555.1\|719019_719205_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373239
CP020664.1\|AVQ70539.1\|696369_696711_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ70549.1\|708546_711558_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|378863
CP020664.1\|AVQ70552.1\|713477_714041_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368559
CP020664.1\|AVQ74204.1\|714061_714451_+\|hypothetical-protein	cmr5gr11	cls000022_cmr5gr11_CAS-III-B	unknown
CP020664.1\|AVQ70547.1\|706364_706622_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ70540.1\|696725_698327_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227621
CP020664.1\|AVQ70544.1\|702110_703145_-\|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	unknown	unknown	gnl\|CDD\|177069
CP020664.1\|AVQ70548.1\|706629_707178_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371328
CP020664.1\|AVQ70553.1\|714511_716476_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	csm3gr7	pfam03787_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187792
CP020664.1\|AVQ70545.1\|703393_705640_+\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|372576
CP020664.1\|AVQ70543.1\|701236_701680_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379519

Protein	Function_ID	Function_description	E-value
CP020664.1\|AVQ70551.1\|712688_713468_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	1.30872e-32
CP020664.1\|AVQ70553.1\|714511_716476_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl\|CDD\|187792	cd09661, Cmr6_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	3.51015e-15
CP020664.1\|AVQ70554.1\|718348_718621_-\|hypothetical-protein	gnl\|CDD\|377648	pfam06305, LapA_dom, Lipopolysaccharide assembly protein A domain. This family includes a domain found in lipopolysaccharide assembly protein A (LapA). LapA functions along with LapB in the assembly of lipopolysaccharide (LPS). Domains in this family are also found in some uncharacterized bacterial proteins.	0.00104526
CP020664.1\|AVQ70550.1\|711557_712682_+\|CRISPR-associated-protein-Cmr3	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.86457e-66
CP020664.1\|AVQ70541.1\|698387_699326_-\|glycosyltransferase	gnl\|CDD\|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	2.88767e-96
CP020664.1\|AVQ70555.1\|719019_719205_-\|hypothetical-protein	gnl\|CDD\|373239	pfam14706, Tnp_DNA_bind, Transposase DNA-binding. This domain occurs at the C-terminus of transposases including E. coli tnpA. TnpA encodes a transposase and an inhibitor protein, the inhibitor only differs from the transposase by the absence of the N-terminal 55 amino acids, which includes most of this domain. This domain consists of alpha helices and turns, and functions as a DNA-binding domain.	5.65127e-12
CP020664.1\|AVQ70549.1\|708546_711558_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|378863	pfam12469, DUF3692, CRISPR-associated protein. This domain family is found in bacteria and archaea, and is typically between 101 and 138 amino acids in length. The proteins in this family are frequently annotated as CRISPR-associated proteins however there is little accompanying literature to confirm this.	1.49845e-41
CP020664.1\|AVQ70552.1\|713477_714041_+\|hypothetical-protein	gnl\|CDD\|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	4.04091e-28
CP020664.1\|AVQ70540.1\|696725_698327_-\|hypothetical-protein	gnl\|CDD\|227621	COG5305, COG5305, Predicted membrane protein [Function unknown].	1.12244e-50
CP020664.1\|AVQ70544.1\|702110_703145_-\|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	gnl\|CDD\|177069	CHL00149, odpA, pyruvate dehydrogenase E1 component alpha subunit; Reviewed.	0
CP020664.1\|AVQ70548.1\|706629_707178_-\|hypothetical-protein	gnl\|CDD\|371328	pfam10989, DUF2808, Protein of unknown function (DUF2808). This family of proteins with unknown function appears to be restricted to Cyanobacteria.	2.25142e-41
CP020664.1\|AVQ70545.1\|703393_705640_+\|molecular-chaperone-DnaJ	gnl\|CDD\|372576	pfam13355, DUF4101, Protein of unknown function (DUF4101). This is a family of uncharacterized proteins, and is sometimes found in combination with pfam00226.	2.31078e-42
CP020664.1\|AVQ70543.1\|701236_701680_-\|hypothetical-protein	gnl\|CDD\|379519	pfam14239, RRXRR, RRXRR protein. This domain is found in bacteria, eukaryotes and viruses, and is approximately 180 amino acids in length. It contains a conserved RRXRR motif. It is often found in association with pfam01844.	1.43824e-51

>CP020664.1|AVQ70548.1|706629_707178_-|hypothetical-protein
MLKVLTKVIKYAKAPALIALSLAVGAGIILPKITLANGNPGLTIFSGVDRKDILDYFLQFGGRPRQMDRYKLYIPAKKLSQGASAFFISYPDYFNGQFDTNKIQVRINGKSLPLKEVVWDKDGRVIQIVPQQAIDPTSKVEIVMSNVRNPELGTYYFTCDVTASGNIPVRLYVGTWIVSIEP
>CP020664.1|AVQ70547.1|706364_706622_-|hypothetical-protein
MAIEKWGNGEIPLRDLRFDNVPFGRTQFAPTLWTKSVTVGAQSLRPPINWDIIPTQVPNIPKPQHPVSPRKSQPKSTICFRVAKI
>CP020664.1|AVQ70546.1|706079_706397_+|stress-induced-bacterial-acidophilic-repeat-motif-family-protein
MTGKSKRGFASMDQAKQREIASKGGKAAHQKGTAHEFTSEEAREAGRKGGEAVSRDRAHMAAIGREGGKNSHKGSGKNTNSGENSPANESVGENSSDFSNSEANS
>CP020664.1|AVQ70545.1|703393_705640_+|molecular-chaperone-DnaJ
MRIPLDYYRILGIPFQVSAEQIDLAHADRGRQLPRQEYSQTAIIARQHLLDEAYQVLSEPDRRRDYDAQFFDPNPLLLNPESSAENLDSQGGELAAASPEYPTPQITIAPADLVGALLILQELGEYELVIRLAETYLDLEPTTRPDMILTLALAYGELSREYWQDKNYEQAASTAAKALTWLEQEQMFPQVASEIRHDCDRLRPYRILELLSQEKKPGLARQRGLNLLEEMLAARGGIDGPGDDRSGLGVDNFLRFIQQLRVFLTQAEQEKIWAKEAQRPSAVGNYLLVYALIARGFAQKQPAAIVAASQRLQQLQKHQDVSLERSICALLLGQTEQASTILEKSQEQEILNYIKEQSGQSPDLLPGLCRYGERWLQTEVFCHFSDLVEQKASLKEYFAEEDVQNYLEELSGFPDEKVPVSVQEKVGEPLESEVTVLKTHTPPTHLNPVPGATPMRESAYSSSHSRPQKPSLARVNGERTSTAVSALRANPQPETLTPYTQGTVVVTAAHHPPAVNPPRRRPRRPHPPAAGNSQQAAPETVKTALVPPKRRRPARRKLRLDRVAILAVGLVGTLAVLSLGVKAIVDSQSPLAALQGEQLPISLHTPILEIPSANAEVIEGTPLGKGTAKETIQAWLVAKSAAFGSEHQKEQLQEVLTGSALEIWQKRAAALQRNNYWRYDHQVDVRSVTNNAKNPNLATVEAIVNEKAMYFYNGKEIVERSYNESLKVRYDLVRQGDKWLIAKTQVLP
>CP020664.1|AVQ70544.1|702110_703145_-|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha
MISERTLPTFNPASIIITKAEGLRLYEDMVLGRMFEDKCAEMYYRGKMFGFVHLYNGQEAISSGIIKALRQGEDYVSSTYRDHVHALSAGVPAKEVMAELFGKATGCSKGRGGSMHMFSAEHKLLGGYAFVAEGIPVATGAAFQSKYRREAMGDASADQVTVCFFGDGASNNGQFFECLNMAALWKLPIIYVVENNKWAIGMAHDRATSQPEIYKKASVFSMVGVEVDGMDVVAVHAAAREAVARARAGEGPTLIEALTYRFRGHSLADPDELRSADEKQFWGERDPITRFAAYLYERDLATREELKEIEEKIQAEIEAAVKFAESSPEPDPSELTRFIFAEDE
>CP020664.1|AVQ70543.1|701236_701680_-|hypothetical-protein
MARVPVISKDGKPLMPTKPSRARRWIKEGKAIGKFNDLGIFYVQLTDEPSDNKTQPIAIGIDPGKLFSGIGVQSSLFTLWKAHLELPFKRVKERMDNRCLMRRGRRGRRINRQLPFNLRAHRQKRFSNRKQGKLAREHLTYAISNYT
>CP020664.1|AVQ70542.1|699437_700220_-|hypothetical-protein
MATTEALNPSQFAFLTNLTADRSSSPNPQEEMDKVIILVNAEAQASGQMSRLSPVTEKMVIALKNAVPKSLAVEVTGTASLWSKMESGKTAQNNLIWCPLTIQLPNWVNFPGKKVYQACRDIEERRAWVAHTLHYKTSQGDSSFGDLWLPITVTSKGLEYGEVIGEGMIPNAYSQPISLERESLKSLHRLAAQLLDNLQAPASVYLLQFRLAHREVVFDRLWPFPAAPAIASLRGQQTDLYAAYWNCLRQQAMLDHSLAI
>CP020664.1|AVQ70541.1|698387_699326_-|glycosyltransferase
MPKYSLIIPIYNEEETIPELYRRVSDVMDSLDDSVELILINDGSGDRSLKLMRELQERDARVCYISFARNFGHQAAVTAGLNFARGQVIVVLDADLQDPPELIPKMIESWQAGYHVVYAQRTKRKKESWFKRLTAYVFYRLLRQLADVDIPADTGDFCLMDRQVVDLLNSMPERNRYIRGLRAWIGFRQTAVKFERDPRFAGEVKYTFKKSLALAINSLVSFSKIPLRLSTYLGLFSALIALLMALLVLYWRLQQPDSPVTGLATILIAVFFLGSVQLISIGILGEYIGRIYEEVKGRPAYTIAEIAGLEIN
>CP020664.1|AVQ70540.1|696725_698327_-|hypothetical-protein
MMDQKKYLPTRSAANFGKFLIITILVIGVGLRFFNLEQKVYSADEVRSIMRFSGYTTQDVREQAFNGEIIDRKDLQYFQHPHSERSLSDALRSMMRNPEHPPLYHLSARFWMQLIPIENSARTFSIFLSILVIPCLYWLCLELFDSSLTGWIAIALFAVSPFQMLVAQNTTQYSLWTLTILLSAISLLRAIRKNTLKSWLWYSLSLALTFYTHLFSATVAIAQALYVILLERLKITRTVVSYVLAAVGSLVLFSPWLFVIFTNLDKIDRNNRYYRQFQTNIIEISQTLFRHTGHVFVDFFHRRGRLESALHLLILLLAIYSLYYLIRYTSRKVWLFLITLIFVPALFQIVPDLLTPSIRSLQARYYLPVFLGMQMAISYLIASYIGSKSPKNWLHYLGQQILLIFLLLGIVSGIFLGLTSDAGLDDQRGTASGVNLEIAPVLNSMSKPIVISDNTPSFFLALSYLVNDQVKFQLFQDGDVESWRRKLNLKELAQNYSNIVVAHPEEDFVNFLNEQYPIRTEKLAGSLIEIKLQ
>CP020664.1|AVQ70539.1|696369_696711_+|hypothetical-protein
MPDYPPAIPPITLPPIENPQQEQTWLRTALHRWLDAEFIPEAINETIAERASQIFLRQRLEGENDLGNLVIAIITEMQAFDFRESFYSEFAIANAVSDLILDSLGIDRCCGQS
>CP020664.1|AVQ70549.1|708546_711558_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MALGYWQAKIWGLLHDPVFKALHSNSGRGDNSFWRDLEVMKLWGKHNPEESTKKILKQIKLADYITSASDRSAIGSLTQFVNYDQQTGLELRHLLSGEPLNLKLADANHQQIASNRTDYLKEQEKRLFNQIPARLRTGILENEAKELFWWLWRCLPQAAAKLLDDENLLLMPAETRIPDGSIWSHASLTAAIAGTLAGYDLTSEDVVNNWPTGKQLSHPYLVSFTFSPVQELIKASRKMGDFWAGSWILHYLSAQVCWQLAQQYGPDSLIYPSLYAQPLIDQWLLEKYADFSSWIDPPGDRQLLTAGFPNIIILLLPKDKVAAAMQTAKSSLLKQWKEISRQVFEKLAKRHWMPKLKENSRTWDSWLNAQWQTYYVGVPIGREDQPLISGEIYKENENIDENQAEAPEKAQSWPDKQNELYNLYDQKALFLEKEQEFLQKAGELAHQKWKRPPFSSNVGSWWSSAVEQNLSALAAVKNARDWQIPTAFGPRSTISGLGPVVHPDGDNDWISEKASKEYWKRNAGLFDGIEQLNATETVKRGLHLILPKLLKNSDQERLDAAYPDLTVGVAGYLKTGGDLDHFHRVCGTISRRLRKDGKNIPSALTQPWGIPYIDDHIEPEYKRYHPRFLNAGWLVEELEIADEEVANYRHQLSQLIDQNYPNNNPADWYVIAAGDGDGMGEWLKGQEMKPYREYIAKSLHQYADHPPTETDTLEKEVQKAFGDFVTLNKPMGPSTHSALSRALLDFSNQLVPYLTEQRYAGRLIYGGGDDVLAYTNLWEWDKWLWDIRQCFKGEKDPHGEFNNAGDYWQWQGEKPPENLAKRPLFTMGKRATISFGIVIAHHSVPLAIALENLWEAEKKAKEHAYKGFDGKKVKKDAVQVRVLYGNGKVLKSTAKFDVFPLWQKLLASNSDASLFEAVAGLWQQHPVPMIEAIEVWVKAFSSRRENLTTDNREAFQKDLSNFLKHLWLTTENDPNDLNEAVRSWMKLAAFMTRKREIKIGGSI
>CP020664.1|AVQ70550.1|711557_712682_+|CRISPR-associated-protein-Cmr3
MYWYTITPLDVLLLRDAKPFSPGERTWAGNTFPPNGHTIAGALSALLDRSKNSYFKITGPFLSFAGDTLYLPRPLGFANSDPLIPISWSDNLTISKNHIFWDRSKPAPLAKAKPHKNCQNRENQEEEENESKYRQYLPCEVILDYLKTGAIDPCQWLVKHKGEDKPWQEEIRSHNAMKPGSKQVEDADGYFVEKAIRMLPGWSIAIGIDVDILTPTTLRLGGEGHRVILEKCDNLGQQWQKLKQKSEENFKQINKAIAYLVTPGIFERRHDNNQAICHSWPWEWKLAHTVNSNQKPGNLVSVATDRAIPISCRIQSKENISIPAPQVFAAPPGSQYYLNQPDRLFQDRPDSPEYHQRWRKLGYSELLWINYKGE
>CP020664.1|AVQ70551.1|712688_713468_+|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MNLIHFYLLSPLHTGGMTQEGNLVGIARESHTTLPYIPSSTIRGKIRSLATEETLKFKLFGNEIDKGAENLEQGDIWIGDGSILWLPISSLSHGVVWITSPLLLRRWTRLTNPRLTIPPEYSCSFKRANRNVYLKDAILKDNDLKDWSTWSSFIPQNSVSSGINQVLVLPDQHCTTLIQMSLWRQVKIKLDEHKSVDGGLRYEEAIPPDTLMYFPWGVTSQANQTKQKSQADFKRLLANNDIIQIGGQESLGRGFVQQL
>CP020664.1|AVQ70552.1|713477_714041_+|hypothetical-protein
MTDNLALAKWSVVDYHRMIAAGILIDRRVELLNGDILEMSPEGPLHKDSGEGLAHFLRQRLKDKAWVREVGPITLENSEPEPDIAVVFPPRSRYRDHHPYADEIFWLIEISDLTLSKDLTEKKRIYAQAGIAEYWVVAIKNREIYVFRQPINSDYQYQEKFTTGTLSAAAFPDIFISLDDLWSGNIF
>CP020664.1|AVQ74204.1|714061_714451_+|hypothetical-protein
MTFDPRTISNPVFNALQELYLNTGDDSRRKEQKKQALELYTYLSTWGMMRLKAEETTLNQEGKKEVVKKYFQCLEELSQINNLSNSQGLTTLKDLSTDDYLGLTGLGLEIAQEFSFWANAIYSDVESGD
>CP020664.1|AVQ70553.1|714511_716476_+|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MSHSPLPPPNRPQKPTLKNQAIKPTNNHQPPQQPPRGGGGNNNGGGGNNNPPQPSPWLNPENQPQPDQSASFVEYLRWMRAADYPHKDATKTQILQKAQENANYTQRLEQLNQRTQLLARDGIAFPVKSTWRIRVGGHRGPESILLPAFDALGMPYIPSSTLRGVARTQAIREIMAANNLEWKDAEKEIAAYFGDINAKEEKNKTGKVIFFDAYPLPSKNGGLEIDMANNIWSWKDDYTQYSPNPNAFFSLKEPIFLIGLRLASNCEDKKILEQVRQWLNKGLQLGIGSQVNSGYGELKPIDDNIHPDNNKNDNDSSFYRLNFELEGQLIHGYQRFTQWQWNHRRNEWQMRSAPVAEVRPTAFKSMLRYWFRVLASGVLPINEVQKIEAELFGGINPKKYGYLQVNILEGKVTQKEPRTNAQGKNDPCGEQRVTLVLSLSSETPKDKQEDVKKLAKYLLWFLADMGGIGQGARRPNYSRKTREYAPWFRGSTLYIDSEEDFWTIAKDVQGFKQQFQQRLRDFYGILDKISETNINTNNLRTVDQVSQNQWIDAADSNCQIFVCAGNEQGGKPHALAILHSDTLKITGKNGQREYDGNLCGKVSGGAKPSPVWIADLGNYQIVTVFGANLNPRQEFIRQLRSNTSPQNFAQIFPL
>CP020664.1|AVQ70554.1|718348_718621_-|hypothetical-protein
MNTISNFLASAIVGGWIMTMAVFAIQNIQPVSLKFLQFESIKVPIGILLAFSLAMGFFIAAIIPAFFRKSKKSPRSRFSPPQSGLDELDF
>CP020664.1|AVQ70555.1|719019_719205_-|hypothetical-protein
MIGIVLKEGIKVGVSKKMEKWAAQELQYAELGDTRRKKRLISIVENLAGHLEQLYHIFRQI
>CP020664.1|AVQ70556.1|719330_719630_-|hypothetical-protein
MVSEFIELRAPKSPKTAPKKPKYPDEPDYCWWHNYCWRANAVRPYKMDAPKGGKEREKRGKGLQSPPDTGHHPKTAVEVEVAAAVVAAAVSGTAVIRSG
>CP020664.1|AVQ70557.1|719985_720450_-|hypothetical-protein
MTPEEPDFSQDIIERREFTLADFIAQEGADFLKGESPVPKLVQVTTEIKQFIAANLGDSSGALQIILQLIVDEELTKVSQNLDNPVHALRLILEEILDNQEFLYELVHRVDVKWGQLYGERPYFQQPNQKPHPEDEYTHSSVRDKLVSLLQQLS

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Crispr_ID: CP020664_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020664_3

1191975-1192063

Orphan

Consensus_repeat	Method
AGAATAAATAAAAATAATCTCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020664_3

>merge|CP020664|3|1191975-1192063|CRISPRCasFinder
AGAATAAATAAAAATAATCTCCTGACTTCAAAGAGGGTGTGGGGTGTGGGGTGTGGGGAAGTGGGAAGTATAAATAAAAATAATCTCCT

>CP020664|3|3|1191975-1192063|CRISPRCasFinder
AGAATAAATAAAAATAATCTCCT	GACTTCAAAGAGGGTGTGGGGTGTGGGGTGTGGGGAAGTGGGA
AGTATAAATAAAAATAATCTCCT

Protein	Signature genes	Signature genes Name	Protein_function
CP020664.1\|AVQ74231.1\|1178683_1178905_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380119
CP020664.1\|AVQ70954.1\|1200078_1200294_+\|DUF2283-domain-containing-protein	unknown	unknown	gnl\|CDD\|378367
CP020664.1\|AVQ70947.1\|1186795_1188430_-\|alpha-D-glucose-phosphate-specific-phosphoglucomutase	unknown	unknown	gnl\|CDD\|100087
CP020664.1\|AVQ70949.1\|1192579_1193764_+\|NADPH-quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|180969
CP020664.1\|AVQ70953.1\|1199875_1200091_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ70955.1\|1200599_1201043_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ70944.1\|1184330_1184978_+\|serine-esterase	unknown	unknown	gnl\|CDD\|223477
CP020664.1\|AVQ70945.1\|1184974_1186315_+\|16S-rRNA-(cytosine(967)-C(5))-methyltransferase	unknown	unknown	gnl\|CDD\|237856
CP020664.1\|AVQ70946.1\|1186316_1186727_+\|Tellurite-resistance-protein-TerB	unknown	unknown	gnl\|CDD\|143581
CP020664.1\|AVQ70956.1\|1201071_1201251_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ74233.1\|1200466_1200646_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ70942.1\|1179171_1179582_+\|nucleic-acid-binding-protein	unknown	unknown	gnl\|CDD\|225266
CP020664.1\|AVQ70950.1\|1194338_1195718_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ70948.1\|1188746_1191716_-\|1-pyrroline-5-carboxylate-dehydrogenase	unknown	unknown	gnl\|CDD\|143442
CP020664.1\|AVQ70957.1\|1201377_1203726_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224397
CP020664.1\|AVQ74232.1\|1179644_1179833_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380119
CP020664.1\|AVQ70951.1\|1195699_1196671_+\|ATPase	unknown	unknown	gnl\|CDD\|223786
CP020664.1\|AVQ70943.1\|1179851_1184081_+\|helicase	unknown	unknown	gnl\|CDD\|197276
CP020664.1\|AVQ70952.1\|1196679_1199397_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224182
CP020664.1\|AVQ70941.1\|1178930_1179179_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP020664.1\|AVQ74231.1\|1178683_1178905_+\|hypothetical-protein	gnl\|CDD\|380119	pfam18135, Type_ISP_C, Type ISP C-terminal specificity domain. This is the C-terminal domain of Type ISP restriction-modification enzyme LLaBIII present in Lactococcus lactis subsp. cremoris. Type ISP restriction-modification (RM) enzymes provide a potent defence against infection by foreign and bacteriophage DNA. This domain interacts extensively with DNA and is known as the target recognition domain (TRD). TRD works by recognising 6/7 base pairs of asymmetric sequence.	1.50034e-17
CP020664.1\|AVQ70954.1\|1200078_1200294_+\|DUF2283-domain-containing-protein	gnl\|CDD\|378367	pfam10049, DUF2283, Protein of unknown function (DUF2283). Members of this family of hypothetical bacterial proteins have no known function.	5.25983e-06
CP020664.1\|AVQ70947.1\|1186795_1188430_-\|alpha-D-glucose-phosphate-specific-phosphoglucomutase	gnl\|CDD\|100087	cd03085, PGM1, Phosphoglucomutase 1 (PGM1) catalyzes the bidirectional interconversion of glucose-1-phosphate (G-1-P) and glucose-6-phosphate (G-6-P) via a glucose 1,6-diphosphate intermediate, an important metabolic step in prokaryotes and eukaryotes. In one direction, G-1-P produced from sucrose catabolism is converted to G-6-P, the first intermediate in glycolysis. In the other direction, conversion of G-6-P to G-1-P generates a substrate for synthesis of UDP-glucose which is required for synthesis of a variety of cellular constituents including cell wall polymers and glycoproteins. The PGM1 family also includes a non-enzymatic PGM-related protein (PGM-RP) thought to play a structural role in eukaryotes, as well as pp63/parafusin, a phosphoglycoprotein that plays an important role in calcium-regulated exocytosis in ciliated protozoans. PGM1 belongs to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
CP020664.1\|AVQ70949.1\|1192579_1193764_+\|NADPH-quinone-oxidoreductase	gnl\|CDD\|180969	PRK07415, PRK07415, NAD(P)H-quinone oxidoreductase subunit H; Validated.	0
CP020664.1\|AVQ70957.1\|1201377_1203726_+\|hypothetical-protein	gnl\|CDD\|224397	COG1480, COG1480, Predicted membrane-associated HD superfamily hydrolase [General function prediction only].	0
CP020664.1\|AVQ70944.1\|1184330_1184978_+\|serine-esterase	gnl\|CDD\|223477	COG0400, COG0400, Predicted esterase [General function prediction only].	1.8235e-50
CP020664.1\|AVQ70945.1\|1184974_1186315_+\|16S-rRNA-(cytosine(967)-C(5))-methyltransferase	gnl\|CDD\|237856	PRK14901, PRK14901, 16S rRNA methyltransferase B; Provisional.	0
CP020664.1\|AVQ70946.1\|1186316_1186727_+\|Tellurite-resistance-protein-TerB	gnl\|CDD\|143581	cd07177, terB_like, tellurium resistance terB-like protein. This family consists of tellurium resistance terB proteins, N-terminal domain of heat shock DnaJ-like proteins, N-terminal domain of Mo-dependent nitrogenase-like proteins, C-terminal domain of ABC transporter ATP-binding proteins, C-terminal domain of serine/threonine protein kinase, and many hypothetical bacterial proteins. The function of this family is unknown.	1.59769e-09
CP020664.1\|AVQ70942.1\|1179171_1179582_+\|nucleic-acid-binding-protein	gnl\|CDD\|225266	COG2402, COG2402, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	9.04685e-14
CP020664.1\|AVQ70948.1\|1188746_1191716_-\|1-pyrroline-5-carboxylate-dehydrogenase	gnl\|CDD\|143442	cd07124, ALDH_PutA-P5CDH-RocA, Delta(1)-pyrroline-5-carboxylate dehydrogenase, RocA. Delta(1)-pyrroline-5-carboxylate dehydrogenase (EC=1.5.1.12 ), RocA: a proline catabolic enzyme of the aldehyde dehydrogenase (ALDH) protein superfamily. The proline catabolic enzymes, proline dehydrogenase and Delta(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH), catalyze the two-step oxidation of proline to glutamate; P5CDH catalyzes the oxidation of glutamate semialdehyde, utilizing NAD+ as the electron acceptor. In some bacteria, the two enzymes are fused into the bifunctional flavoenzyme, proline utilization A (PutA). In this CD, monofunctional enzyme sequences such as seen in the Bacillus subtilis RocA P5CDH are also present. These enzymes play important roles in cellular redox control, superoxide generation, and apoptosis.	0
CP020664.1\|AVQ74232.1\|1179644_1179833_+\|hypothetical-protein	gnl\|CDD\|380119	pfam18135, Type_ISP_C, Type ISP C-terminal specificity domain. This is the C-terminal domain of Type ISP restriction-modification enzyme LLaBIII present in Lactococcus lactis subsp. cremoris. Type ISP restriction-modification (RM) enzymes provide a potent defence against infection by foreign and bacteriophage DNA. This domain interacts extensively with DNA and is known as the target recognition domain (TRD). TRD works by recognising 6/7 base pairs of asymmetric sequence.	7.1924e-10
CP020664.1\|AVQ70951.1\|1195699_1196671_+\|ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	5.69837e-25
CP020664.1\|AVQ70943.1\|1179851_1184081_+\|helicase	gnl\|CDD\|197276	cd09179, PLDc_N_DEXD_a, N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain. N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain. All members of this subfamily are uncharacterized. Other characterized members of the superfamily that have a related domain architecture ( containing a DEAD/DEAH box helicase domain), include the DNA/RNA helicase superfamily II (SF2) and Res-subunit of type III restriction endonucleases. In addition to the helicase-like region, members of this subfamily also contain one copy of the conserved HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue) in the N-terminal putative catalytic domain. The HKD motif characterizes the phospholipase D (PLD, EC 3.1.4.4) superfamily.	2.50333e-19
CP020664.1\|AVQ70952.1\|1196679_1199397_+\|hypothetical-protein	gnl\|CDD\|224182	COG1262, COG1262, Uncharacterized conserved protein [Function unknown].	9.89043e-68

>CP020664.1|AVQ70948.1|1188746_1191716_-|1-pyrroline-5-carboxylate-dehydrogenase
MVIQIESTQNYETKTQEIARQLLAETREKKGLWSALQDQMRWDDKLLDWAMSNPNLRVQLFRFIDCLPALRSNAEIANHLQQYLGDASVELPSALKSILNFSDPNSLPAQTAASLISKSVETLARKYIAGEDLEQITRTVTRLRKEKMAFTIDLLGEAVITEAETQVYLQSYLDLMTHLAQEASKWNKVSQIDEADGELLPQVQVSVKLTAFYSQFDPMDPIGSKEKVCDRIRLLLRRAQELGVAVHFDMEQYVYKNLTLAILKELLLEEEFRSRTDIGITLQAYLRDSAQDLQDLINWAKKRGYPLTVRLVKGAYWDQETIKSRQNHWPQPVYNEKSATDANYERMTRLLLENHQYLYAAIGSHNVRSQALACAIAESLEIPRRRFEMQVLYGMGDQLAKALVKRGHRVRVYSPYGQLLPGMAYLIRRLLENTANSSFLRQNLEDRPVEDLIAAPRVLGNDNPIIPGFPNAPDTDYANEQLRNKASQALTFVKNSLGKTYLPLINGEYVATNVQINSVNPCNPQEIVGKVGLIEVEQAEKAIIAAKQAFPAWKRTPVAKRAEILRKAADLMEARRHELSAWICLEVGKVIQQADPEVSEAIDFCRYYASEMERLDLGHNFDVAGENNRYFYQPRGITLVISPWNFPLAIAVGMTVAALVAGNCTLLKPAETSSVITAKFAEILLEAGIPAGVFQYIPGKGSQVGAHLVSHPDVHLIAFTGSREVGCRIYTDASIVQKGQKHLKRVIAEMGGKNALIVDESADLDQAVVGAVKSAFGYTGQKCSACSRIIVLESVYDSFVDRFVEATKSLNIGPTDLPSTEVGPVIDEKAQARIREYIETGKKEAELALEMPIPEVGYFVSPTVFKNVPPDAVIAMEEIFGPVVAIIKVSNFEQALAVANGTDYALTGGLYSRTPAHINRAMQEFEVGNLYINRGITGAIVSRQPFGGFKMSGVGSKAGGPDYLLQFLEPRHISENIQRQGFAPIEGAD
>CP020664.1|AVQ70947.1|1186795_1188430_-|alpha-D-glucose-phosphate-specific-phosphoglucomutase
MTIETVATKPFSDQKPGTSGLRKSVPVFQQPHYLENFIQAIFNTLDGIEGQTLVVGGDGRYYNRQAIQTILKIAAANGIGRILVGTDGIVSTPAISGLIRENNAFGGIVLSASHNPGGPEGDFGIKYNITNGGPAPENITDAIYAETKVISSYKILSGADINLDRPGSFKLGTMDVEVIDAVTPYVKMMEKIFDFDRIQALLTSGKFKMCMDSLHAVTGPYAYALFEQRLGAPKGTVLNGIPLEDFGGGHPDPNLVYAHDLVEILFGQEAPDFGAASDGDGDRNMILGQNFFVTPSDSLAVLTANAHLVPGYQNGITGVARSMPTSAAADRVAAKLGIDCYETPTGWKFFGNLLDAGKATLCGEESFGTGSNHIREKDGLWAVLFWLNILAVKGESVEEIVRSHWQEFGRNFYSRHDYEEVALEPAKEMMARLQKLVLDLKGKQFGNYEVEYADDFSYTDPVDGSVSKNQGIRIGFTDGSRIIYRLSGTGTKGATLRVYLESYEPDASKHDIDTQKALQPLIDLAEEIGQIRQSTGREQPTVIT
>CP020664.1|AVQ70946.1|1186316_1186727_+|Tellurite-resistance-protein-TerB
MKNKQLLKILIGVAWIDGVIQPSERSYLRQVAVREKLDDDPEIKPLLSELKPVKTGECYRWLESYLGDNPSPETYQDLITSISTLIYSDDDVDIQEAKLLTKVQSLDPTHDSHRSILDKLVTGIQKLYHKAITESN
>CP020664.1|AVQ70945.1|1184974_1186315_+|16S-rRNA-(cytosine(967)-C(5))-methyltransferase
MNNARQLALLILRDIDRSSAYPDRALDRHLSASSLNCLDKALTTEIVYGIIRRQRTLDALLDRLGKKTAAQQPPDLRRILHIGLYQLRYLSQIPPSAAVNTAVELTKISHLGKLAAVVNGMLRQYLRLTANGDDPLILPENTASRLGILHSFPDWLVQLWLDRFSVTETEQLCQWFNRSPDLDIRINPLKTSREALENELESANITFNHLKLPLACRLTSGLGNIERLEGFRAGNYTLQDISAQLVTYLLDPQPGETIIDACAAPGGKTTHIAELMGDRGRILACDQTASRLRQLEANIKRLDLKAIEIHLGDSRDRPQWCGIADRVLIDAPCSGLGTLHKRPDIRWRQTPENLPVLAKRQGELLASAATWVKPKGILVYATCTLDPLENERVIEQFLAAHPDWKMAPPDSNSSFSEYYTETGAIEVLPHRHNQDGFFMAKLVKEV
>CP020664.1|AVQ70944.1|1184330_1184978_+|serine-esterase
MEKKENCEEKTLSFNPIVIPPSPENPARYLVIMLHGWGADAMDLAPLASMLDLADCQFLFPNAPFDHPQVPGGRAWYALETSDYQGLVASRQQLQDWIISLEATTGIPLERTFLTGFSQGGAMTLDVGLSLPLAGLGSLSGYLHGEPHPQGPQNVLIVHGKQDPVVPIAAARQARDLLLGLGVNVEYHELNMGHEIPIPALTILRQFLRNRLETA
>CP020664.1|AVQ70943.1|1179851_1184081_+|helicase
MLETVIQDLIKKQRPYYHPEGDYIKGVNNNYWLVFKHRDAENLLRNIVSFLGLQKHSTHKLFRIELNTAHIFEYTPKREGNIPSIALLRTSNLTIIEQFLNLENASKEESLIRGTFIEIEHKKRRRFNLPEQLDKYNQFIAAYLERTKIYRRSTAYFNSGVLKLYEEPLFNLVLNEGQIKLLMDWQGFTNKRDVQELEKLHNPEYRQQYITRTLTECLQGLADKTFSSTTILAELVRLGILTIKLIKMQETRGIYHKKTGILTDSLGNSILHEGSDNFTGAAHSSNAESITFLYYSDSLDLETIQQSIIEFDQEWQEPELSFDLTQEFLQQVLAEKQRRQQQIQPQIETITPDEFPAGETTSLEIQGKNLDKIEEIEVPDNPLIAVEIEEKQPHLLTGTVTVDPEHPSTSLKTFRVKEKQVTYQITPTQAPTIKQEITLPEWEEIAGFKQAIELILQGKQGTPDDFLYWLAQQRPHLLNIQSSNILDRLVNQDILFEHQKSGAQHCLRVMQNFGVVVCADAVGLGKTRLAAAVTKLYLEENPQTKIAIIAAKKLHPNWEREMAELGLLAKKHYELYNKNLMSRGGDRFYDEFTRHGGAADLVIIDEAHEGIRNYNNRIHKTCLQIKEHDRQIERQRYYLLLTATPWNNRREDIYNILSPFLTRPEGFQELGFPPEVKQWFASREIGIENFTDTTNIFRRTYRELFLQRTRKMLREATPDLQLYAQRLAQWLPVQFEPETEQALERIFSQFEDNLFIPFADPIRYLTSTVEQRSLLKNQRRMFLQRAESSMYALRRTIKNFSDRISVLKQQLEQVTPDAEGLKQFLLQHYKFQAEKTGRETDWLGIEENGDEDYWEDEEDEEETDSNKGEKRQQLRRSIDLATDKLKNNPLEAKNIYNRILADCHSDLEQLQQISVLLANEFVTDHKRQQVSRKVMELVADGHKVLLISTFSDTVIDYYRYMSQNQVIASKGIGMAMGSHKLYYTDEKTPVKIAPNNALRGNNKQTGLQRQQLFRLFAPEATCKNPNERPLPEQEIAVLIGSETLSVGQNLQDADYLINIDLPWNPMVLEQRIGRIDRPKSHPCQYIYIYYANSESQLLRQAGRLANLNKKLIGELAKDDKIPHISNVEELGASVYGDTYFDDEILPGYIDFIHSLIKARQLEQESFQEQTYQKQETSRDLYSQNELLHSEELRKLYERLGKNYQPNPLTIGQFTTWELPTSLVALTLDYFDPNGQPIPEQNQLIYWNNLSRENDGFGVAIATAFKTPQASQIVPAKRIINLAQQLYEQLVQVKQQLSQDLEETAILENIKLNSERLSRIQKRIQIMSAFPADVNRKIVKNTLNKLSQAKETKKVQKLLKDYTDGEPSQLDDQKFILGLIQGTEQLNLLTFDTAKPSSFKLSLSAMLLRI
>CP020664.1|AVQ74232.1|1179644_1179833_+|hypothetical-protein
MRLPLFSYLGGYQVCQKWLKDRKGRTLSDEDILHYHKIVVALAETIKLMQLIDAAISSFPIK
>CP020664.1|AVQ70942.1|1179171_1179582_+|nucleic-acid-binding-protein
MSKERLFIDTAFIQAVLNKQDQYHAQALKLLPKVKNALEVWTTEAVLMEVGNALSTFNRQKAANFIKQCYHTQNMRVVNISPQLFHQGLTLYESRLDKNWGLVDCISFVVMEQQHLTDALTTDRHFIQAGFQVLLV
>CP020664.1|AVQ70941.1|1178930_1179179_+|hypothetical-protein
MTKQLTVIFDGKVFHPETDIDLKSNTRYLISIVSEAEIPEKPSGDAWDILEDMAGTIEAPEDWSKEHDHYLYGTPKREVNDE
>CP020664.1|AVQ74231.1|1178683_1178905_+|hypothetical-protein
MNKQGDCFRGVPEAVWNFYIGGYQVCQKWLKDRKGRTLSDEDILHYHKIVVALAETIKLMQLIDAAIPGFPIE
>CP020664.1|AVQ70949.1|1192579_1193764_+|NADPH-quinone-oxidoreductase
MAKIETRTEPMVLNMGPHHPSMHGVLRLIVTLDGEDVIDCEPVIGYLHRGMEKIAENRTNVMYVPYVSRWDYAAGMFNEAITVNAPEKLADIAVPKRAQYIRVIMLELNRIANHLLWLGPFMADVGAQTPFFYIFREREMIYDLWEAATGMRLINNNYFRIGGVAVDLPYGWVDKCEDFCDYFDPKVDEYEKLITNNPIFRRRIEGIGCITRDEAINWGLSGPMLRASGVKWDLRKVDHYECYDDFDWEVHWETAGDCFARYLVRIREMRESVKIIRQALKGLPGGPYENLEAKRMAEGKKSAWNDFDYQYIAKKVAPTFKIPKGEHYVRLESGKGELGIFIVGNDDVFPWRWKIRAADFNNLQILPHILKGVKVADIMAILGSIDIIMGSVDR
>CP020664.1|AVQ70950.1|1194338_1195718_+|hypothetical-protein
MLKSGEIRLSDEDVETLRKAKDAYEGDYSCASEKTEKILIEASRWLLEAFLEEYRSRTKTSSYTIPLNVLKAWMTSSPQSGATKEVLEPKGKKLYLQNKSDFKGFENKKKREYITQNKINTTRIEDINDNLIHLTFDEVLNFLLDSSILKVIGISGDSLRFCTEQKYGLGKKGRTSKQSYIVQAYCEVLVLDFESLQCCQLHHQNPKNQQTNNEKIYRVLTKFNYTNLVNFTSSIAAKTLREGSIYIPPCPHQYRVLCLRRLEKEILITNNLPVKPIVFKFQGDGQEEWDSYSLHEHFFDNSGGIKNLKANNFCLIFEGIDCADFSRLKDIDSFWQNLITNARKIQNSPIKGFLLMIWLDYGNSNDWRDKDKLSELSPIHRLQIDSCFEKRSFQEIIPTFAQQLQLGCDLQDETTDLFKSTLQQLWKNSDQGKIEDTLKAFYQQFQGQLSREHRWLNYP
>CP020664.1|AVQ70951.1|1195699_1196671_+|ATPase
MAKLSLTYRGKIQPKSDLYYEPIQQKIYPYDAGDELIEVVNLAIELGMPLLLEGEPGCGKSRLAHALVYEFNYRQESNPIKYYEWIVQSTSKAEDSLYQYDYIGRLQAAQISGILSQKGAGESSSEQKNPATSKDWVDLQPLGKAFKQSQDKQEQSVVLIDEIDKADRDFPNDLLLAIESRRFFIKETGELIQANDQAFPLIIITSNQEKNLPNAFLRRCIYHYIELPNQERLRKILTERFTDAEQEVIIKAVDRFLEVRTSQDETKSEGEKKVSTSELIAWFKSLLKYKTEEIIAKLNEDKLPHASVLLKSRTDLQDYGTRG
>CP020664.1|AVQ70952.1|1196679_1199397_+|hypothetical-protein
MTSPLLELFYQLRDEQGFLLSIEQYYRVENYLIQKLANDSDIAIQENPNLDNPKIKLLCQALWVKSPKEKEKFDQAWTEMLQLQPEINIEIAKKTPIRHPEESISKIINPMDDRESPSLEITPSGDTPIAPETSFPQIATAIEKRKKITSLDNPDYYPIGIAKLQESWQQLRPLPLESPRQTWDLKATVMATAKRGFFDQIIYQKKQLYRREIIIFIDCSDSMIPFAGFGRIMKQTWANVPHFYFDNLIRDEVLRQENGWESQSLTKVLSNYSPEVTSCLILSDAGAARKRYVEERLSATETLIRRFSRRFSRVAWLNPLPYHRWYGTTAIDIADLAEDIPNFSMFELTTEDWENLITWLKEEAIPPRHFPFNPNQFHQGDNWDEDEDFFSAKSRLRLFEEENEPNTRELAKRAAFPLSLSPNLLYYLRQHQDKNNQAPWYAIADILLSSLVRKIDRELYEMSPDVRKLLLEKLTPEELKSLAYQLQTYIQEQIGDYCSKSVYWQNQQWLALAYLKPSQAVNEIKQVLAEAIKNNNRVRLVRLTALLKNISAALADYEPLLLLNEPIAAYSRGDLNTVGNVLQLSPEDEGTLQKRLIDKVAAIVPYNENLFTAETVLVNKTGQVIERKPVKAYFYDEKLAEVGNRKKAQNYIRMMYIPQGEFWMGTEDEEIERLVKKFDSKVFTRERPQHLVKVPAFYMSQTPITQAQWRAIAATAKIDIDLETNPSSFIGDELPVERVNWYQATEFCKRLSRETKREYRLPSEAEWEYACRAGTKTPFHFGETITGELANYNAGYTYAGEAKGEYRQQTTPVGQFPPNAFGLYDMHGNVWEWCADTWHDNYDGAPTDGSAWIENGNDNRSPLRGVSWYYYPYYCRSAFRDGYHRRGSYYNYYGFRVVCGAGRTV
>CP020664.1|AVQ70953.1|1199875_1200091_+|hypothetical-protein
MKGQEKLVQETLSQPDEIRRSRSDPNVYLFYQLQRPKRWLCAIIRKLNGDGFLITTYPTDAIKEGEILWQK
>CP020664.1|AVQ70954.1|1200078_1200294_+|DUF2283-domain-containing-protein
MAEVNVYYDPMGNTLTVWFGDRSSEYLCEETGDEVILMKNQKGEVIGFEKLNYRISENRNLKISLETAIPL
>CP020664.1|AVQ74233.1|1200466_1200646_+|hypothetical-protein
MKITYQKVNLKAPKTETAYWRSQSYQTRLSALEEIRQEYHQYKYNAEPRLQRVYTIVKR
>CP020664.1|AVQ70955.1|1200599_1201043_+|hypothetical-protein
MLNQDFKEFIQLLNDNQVRYLVLGGYAVALHGYPRYTKDIDIWIEMSSLNAYNLIKALEGFGFGSLGLTIDDFLTPDQVIQLGYPPNRIDLITTPDGVEFQTCYLSRIEVKIDDIIVNFIDLENLKKNKKASGRLQDLADLENLEID
>CP020664.1|AVQ70956.1|1201071_1201251_+|hypothetical-protein
MQGSPLQRISRGSTSCLTHQETEKDPPLCSSKPLPFASLFPDRRPTPHPTNKLFQPTLI
>CP020664.1|AVQ70957.1|1201377_1203726_+|hypothetical-protein
MNHFLHSFTVFPDSARKSRSYSLGKLRRPLIFLFTVGCLTSVVGYRFYNQPKLAVGTISPVTIIAPEDARFQDQETTALKRQKIRAGLLPRLKRDPQTTAQIERSLQDTLGQLSQIRPILRRNSILMGRTISNATMETLLTFSAPQWSTLQSRLNYEESFTNLLTKEQEYAVSEIQAYRQRVTKGSFEQFIDRLGQLRQIKEQTSQNYRHSSLNKLKYADLITVAQMGDREWQNLEKAILQAGRRIWVQGIPPGISTSHLQDTIAVQISSDRLTGRQQSLAENILLAALEGQTNLIEDREATKEQATKAVEAVDMVMSDAQAGQIIVKAGETITQAQFVLIDGFGLSERGINWMGLGSTAILVTSAIGTFCLVAQRLHRPLRHRDFLLLGLLSFTTPILAIANIPFTNLAAVGLLVSSFYGPTLAVTQVLLTAGLSLFSIQGISADLIAGTIGGLLAAMIAAKLRSRDELSLLGMGIGVSQGGVYLLTYLIVSATASTIIYTLLPTALVYGLSGIAWTVIALGLSPYLERCFDVVTPIRLVELSNPNCSLLKRLATEAPGTFQHTLFVACLAEAAARKLHCNVELIRTGTLYHDIGKMHDPLGFIENQMGGPNKHDEINDPYVSAEIIKKHVSEGLVMARRHGLPRVVRDFIPEHQGNLLISYFYQQALQKSAQNGQEFVDEAVFRYDGPIPQSRETAIVMLADSSEAALRSLKEASPEQAMDMIKKIFQARWRDQQLVDSGIRQEELPIIAEVFVQVWQQFHHQRIAYPKAVLEVSSAKKI

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Crispr_ID: CP020664_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020664_5

1490913-1495522

TypeIII

Consensus_repeat	Method
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CRISPRCasFinder
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CRT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	PILER-CR
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	PILER-CR
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CRT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	PILER-CR
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	PILER-CR

62 spacers

csm3gr7,cmr5gr11,cmr4gr7,cmr3gr5,cas10,WYL

The CRISPR arrays of CP020664_5

>merge|CP020664|5|1490913-1495522|CRISPRCasFinder,CRT,PILER-CR,PILER-CR,CRT,PILER-CR,PILER-CR
GCAGACCCTAATTAAACTTGCTAAGAAGTTAAAAGAGTTTACACAATAAAAAAAGGAGAAAATTATGCGCCTTACTGACGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGTCGTGACTATGCGACAGGTGAATGGGTTGCATTGACGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAGAAATAGAATTCTTGGCGCAAGTTAAGGAAGTCATCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGCTGTGCCTTCGGTCCCATTGGAGTGATTTACCTTTGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGTAAACGTACAGGGGGAATTTGTGCATTTCGCATGAGTTTAAGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAAAAACTACTCGAAACCTTCGCTCAATGGTTCGAGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCGTAACCCAAAAAGAACAAACCGTAAAAGTATTTGACATCAAGCGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGACAAATGCAGTCAATGCAGTCATAGAAATTTATGTCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATTTTAAAAAAAATGTCTAAAATGTCTAAACCGCCTATTGAGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGATGTCTCTCAAGTTGCTGGCTTGGCACACCGACCCAGCTGATCTTCCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAATATTCTGCGGAAAAGACGCCACAAACCTACCAAAGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGTTTCTCGCAGAAACCTTATACCGTCTGAAATCAGACGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGTTACGGGCATTAGTTGTCCCAAGAGAGGGGCTTTGGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATTAACCTGGATCTTTTCAGTGGTGTTCGGGGCATCCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAGGAGGTTACAGGGGTATGCATCGTAGGGGAGGAATGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCCCTCGGCTTTCGAGATCTCCTTCCCTGCCGCTGACTCCAGTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATTTAAAAATGCCGCAGGTGATTCGGCCTCTGACGTTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCAGAGGGATTATCACGGTGAGTAGTAAGGATGAGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGCTTGTGAGACAATACAAAAAGTACTGACACCGTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAGCTACCTTACGACGATTATTGAGGACTACCTAGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGCGGAGGTGGATCGCCTCCGAGATGAAGTGGCCACAAAAGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATTGCTAGAGGAGTTTTTAGAGCTCCTACAAGTCCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAATGTTGTTATTCTTCAAGGATAGCAACATCACCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAGCGCCAAGCTCAAAGAAATCGCCACTGTTCTGCACGAATTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAAAGAAAGAAGCGCGTGCTGCTTTCTACTTTGTGAGTTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATAGTTTCAATCCGTTCCGTGAGTTACAACGCGCTCGAATCCTGGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATGGGATTGTTCGCCTGCGAACAGCAGACCCCAAAAGAGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGTTGTGCACCCCTTCTTGGTGCTTGCGAGGAGCCTCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAAAGCCCAGCTCCGCGCTGAGGAAGTATTCTGCCTAAAGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAAGTGCATTGGAAACGTTAGCTTTACAAACTGTCTCGAGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATGATCATTTCAAAGAGTAAAGCCACGGTGGCGATCTCTCCAGGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGTGGAGTATTTTTTGGGTTTCTATTCTGGGTAGACTTCTCCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAGGTTTGCAACAGCCTTGACTTCCATGATGGTGTTTTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAACATCCTTCTCCAAGAGGAGTTGGAAAAGAAGAAGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGTTGTCCCCGAGGGCAAGATCCTTTTGCGTCACTATATGATGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCCTTGAACGAAGCTCCCCAGCTTCTGGGTGACGTCCCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGTGGATCATCAGGCCGCCCATGCTGGTGACCATGTGACGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAGATGGCAAGTCCGTGAAGGTTTCGGGAGACTCTGTCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGTTATTTGACAAGCCCACCATAGCCTGTGCACTTCGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGGGGAAATCTAATAGACTACCTCGTAGTGGTCTATGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGTTGGCACAAACCATCCTTTACGCCGGCCAACTGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGTTTCGAGTGAAATTGTGCTGTTGCGTAAAGTGCTGGTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCTTAAAATGCGTAACCTTTTCCCCGAGGCTACACCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATGAATTTTTTGTTTGTCAAAAACTTTTTTTGATAAACTCAGCCCCAACACCCCTAAAAAGGTGCGACGGCGATACATCAGAAGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCTGAAATTCAGATCAAAATCATCGCCGCGATTGTTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGCTTGAGTTTGTGGGTATCCCTTTTTCTGGGTACTTGCGGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAGAACAACATCTCAATCTCATCGAGATGTTGGACATGAAGGGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGGTGTGGCAAAGCGATGGTTTGATTGGCGTGCTGAAACTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGTTTTATGAGGAGGGCCGAACAAATCCTAAAATCCTTTTGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATGACATTAAAGTCATAGCAAAAGGGGTGAAGTACGAGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAAAACACGATTGGGACTATTTGATCTTCTGGATCAAGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGTGTTCACCACTCGTCTCGATTGCGACTCTGTCGCTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGAGCATTCAAATTATGGCAACAGCAGAGATCCGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGACTTTCGGGGAATAACCCCCCCCTTTAAAAAGCAAAGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAGCAACGGTAGCCATCTATCAAAATGACTATCGAGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAATCAAAGAAGCCTTTGAAGAAGGCGATTTTGACTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATGCGTGCAAACAAATCATATGCGGCGAGCAGTGTGGTATTTACGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGTGGCTCGGTTGATGACAGGGGGTACTTACATGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCCGAGTTGGGTGAAAACCTCGCTGGCTCCTGGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCAAGAAAAGCCCTGCCTCTGTAATCCAGCGGGAGGGTGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGTCATTTCCAGCTTCGTGACTGGGGACTGCGTGAGTTGGACTATGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATGAAATCGTTAAATCTTTGGAGGAATTTTTATGCCTCCAAGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG

>CP020664|5|5|1490913-1495522|CRISPRCasFinder
GCAGACCCTAATTAAACTTGCTAAGAAGTTAAAAG	AGTTTACACAATAAAAAAAGGAGAAAATTATGCGCCTTACTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TCGTGACTATGCGACAGGTGAATGGGTTGCATTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGAAATAGAATTCTTGGCGCAAGTTAAGGAAGTCATC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTGTGCCTTCGGTCCCATTGGAGTGATTTACCTTTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TAAACGTACAGGGGGAATTTGTGCATTTCGCATGAGTTTAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAAACTACTCGAAACCTTCGCTCAATGGTTCGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CGTAACCCAAAAAGAACAAACCGTAAAAGTATTTGACATCAAGCG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ACAAATGCAGTCAATGCAGTCATAGAAATTTATGTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTTTAAAAAAAATGTCTAAAATGTCTAAACCGCCTATTGAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GATGTCTCTCAAGTTGCTGGCTTGGCACACCGACCCAGCTGATCTTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AATATTCTGCGGAAAAGACGCCACAAACCTACCAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTCTCGCAGAAACCTTATACCGTCTGAAATCAGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTACGGGCATTAGTTGTCCCAAGAGAGGGGCTTTGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTAACCTGGATCTTTTCAGTGGTGTTCGGGGCATCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGGAGGTTACAGGGGTATGCATCGTAGGGGAGGAAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCCTCGGCTTTCGAGATCTCCTTCCCTGCCGCTGACTCCAGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTTAAAAATGCCGCAGGTGATTCGGCCTCTGACGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CAGAGGGATTATCACGGTGAGTAGTAAGGATGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTTGTGAGACAATACAAAAAGTACTGACACCGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGCTACCTTACGACGATTATTGAGGACTACCTAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCGGAGGTGGATCGCCTCCGAGATGAAGTGGCCACAAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTGCTAGAGGAGTTTTTAGAGCTCCTACAAGTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAATGTTGTTATTCTTCAAGGATAGCAACATCACC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGCGCCAAGCTCAAAGAAATCGCCACTGTTCTGCACGAATT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAGAAAGAAGCGCGTGCTGCTTTCTACTTTGTGAGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATAGTTTCAATCCGTTCCGTGAGTTACAACGCGCTCGAATCCTGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGGGATTGTTCGCCTGCGAACAGCAGACCCCAAAAGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGTGCACCCCTTCTTGGTGCTTGCGAGGAGCCTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAGCCCAGCTCCGCGCTGAGGAAGTATTCTGCCTAAAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAGTGCATTGGAAACGTTAGCTTTACAAACTGTCTCGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGATCATTTCAAAGAGTAAAGCCACGGTGGCGATCTCTCCAGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGGAGTATTTTTTGGGTTTCTATTCTGGGTAGACTTCTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGGTTTGCAACAGCCTTGACTTCCATGATGGTGTTTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAACATCCTTCTCCAAGAGGAGTTGGAAAAGAAGAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGTCCCCGAGGGCAAGATCCTTTTGCGTCACTATATGAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCTTGAACGAAGCTCCCCAGCTTCTGGGTGACGTCCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGGATCATCAGGCCGCCCATGCTGGTGACCATGTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGATGGCAAGTCCGTGAAGGTTTCGGGAGACTCTGTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTATTTGACAAGCCCACCATAGCCTGTGCACTTCGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GGGGAAATCTAATAGACTACCTCGTAGTGGTCTATG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGGCACAAACCATCCTTTACGCCGGCCAACTGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTCGAGTGAAATTGTGCTGTTGCGTAAAGTGCTGGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CTTAAAATGCGTAACCTTTTCCCCGAGGCTACACC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGAATTTTTTGTTTGTCAAAAACTTTTTTTGATAAACTCAGCCCCAACACCCCTAAAAAGGTGCGACGGCGATACATCAGAAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CTGAAATTCAGATCAAAATCATCGCCGCGATTGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTTGAGTTTGTGGGTATCCCTTTTTCTGGGTACTTGCGGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGAACAACATCTCAATCTCATCGAGATGTTGGACATGAAGGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GGTGTGGCAAAGCGATGGTTTGATTGGCGTGCTGAAACT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTTATGAGGAGGGCCGAACAAATCCTAAAATCCTTTTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGACATTAAAGTCATAGCAAAAGGGGTGAAGTACGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAACACGATTGGGACTATTTGATCTTCTGGATCAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGTTCACCACTCGTCTCGATTGCGACTCTGTCGCT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GAGCATTCAAATTATGGCAACAGCAGAGATCCGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ACTTTCGGGGAATAACCCCCCCCTTTAAAAAGCAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGCAACGGTAGCCATCTATCAAAATGACTATCGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AATCAAAGAAGCCTTTGAAGAAGGCGATTTTGACT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGCGTGCAAACAAATCATATGCGGCGAGCAGTGTGGTATTTAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GTGGCTCGGTTGATGACAGGGGGTACTTACATG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCGAGTTGGGTGAAAACCTCGCTGGCTCCTGGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CAAGAAAAGCCCTGCCTCTGTAATCCAGCGGGAGGGTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TCATTTCCAGCTTCGTGACTGGGGACTGCGTGAGTTGGACTAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGAAATCGTTAAATCTTTGGAGGAATTTTTATGCCTCCAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG

>CP020664|5|2|1490913-1494095|CRT
GCAGACCCTAATTAAACTTGCTAAGAAGTTAAAAG	AGTTTACACAATAAAAAAAGGAGAAAATTATGCGCCTTACTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TCGTGACTATGCGACAGGTGAATGGGTTGCATTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGAAATAGAATTCTTGGCGCAAGTTAAGGAAGTCATC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTGTGCCTTCGGTCCCATTGGAGTGATTTACCTTTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TAAACGTACAGGGGGAATTTGTGCATTTCGCATGAGTTTAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAAACTACTCGAAACCTTCGCTCAATGGTTCGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CGTAACCCAAAAAGAACAAACCGTAAAAGTATTTGACATCAAGCG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ACAAATGCAGTCAATGCAGTCATAGAAATTTATGTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTTTAAAAAAAATGTCTAAAATGTCTAAACCGCCTATTGAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GATGTCTCTCAAGTTGCTGGCTTGGCACACCGACCCAGCTGATCTTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AATATTCTGCGGAAAAGACGCCACAAACCTACCAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTCTCGCAGAAACCTTATACCGTCTGAAATCAGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTACGGGCATTAGTTGTCCCAAGAGAGGGGCTTTGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTAACCTGGATCTTTTCAGTGGTGTTCGGGGCATCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGGAGGTTACAGGGGTATGCATCGTAGGGGAGGAAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCCTCGGCTTTCGAGATCTCCTTCCCTGCCGCTGACTCCAGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTTAAAAATGCCGCAGGTGATTCGGCCTCTGACGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CAGAGGGATTATCACGGTGAGTAGTAAGGATGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTTGTGAGACAATACAAAAAGTACTGACACCGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGCTACCTTACGACGATTATTGAGGACTACCTAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCGGAGGTGGATCGCCTCCGAGATGAAGTGGCCACAAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTGCTAGAGGAGTTTTTAGAGCTCCTACAAGTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAATGTTGTTATTCTTCAAGGATAGCAACATCACC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGCGCCAAGCTCAAAGAAATCGCCACTGTTCTGCACGAATT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAGAAAGAAGCGCGTGCTGCTTTCTACTTTGTGAGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATAGTTTCAATCCGTTCCGTGAGTTACAACGCGCTCGAATCCTGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGGGATTGTTCGCCTGCGAACAGCAGACCCCAAAAGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGTGCACCCCTTCTTGGTGCTTGCGAGGAGCCTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAGCCCAGCTCCGCGCTGAGGAAGTATTCTGCCTAAAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAGTGCATTGGAAACGTTAGCTTTACAAACTGTCTCGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGATCATTTCAAAGAGTAAAGCCACGGTGGCGATCTCTCCAGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGGAGTATTTTTTGGGTTTCTATTCTGGGTAGACTTCTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGGTTTGCAACAGCCTTGACTTCCATGATGGTGTTTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAACATCCTTCTCCAAGAGGAGTTGGAAAAGAAGAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGTCCCCGAGGGCAAGATCCTTTTGCGTCACTATATGAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCTTGAACGAAGCTCCCCAGCTTCTGGGTGACGTCCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGGATCATCAGGCCGCCCATGCTGGTGACCATGTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGATGGCAAGTCCGTGAAGGTTTCGGGAGACTCTGTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTATTTGACAAGCCCACCATAGCCTGTGCACTTCGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GGGGAAATCTAATAGACTACCTCGTAGTGGTCTATG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGGCACAAACCATCCTTTACGCCGGCCAACTGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTCGAGTGAAATTGTGCTGTTGCGTAAAGTGCTGGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CTTAAAATGCGTAACCTTTTCCCCGAGGCTACACC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATGAATTTTTTGTTTGTCAAAAACTTTTTTTGATAAACTCAGCCCCAACACCCCTAAAAAGGTGCGACGGCGATACATCAGAAGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CTGAAATTCAGATCAAAATCATCGCCGCGATTGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTTGAGTTTGTGGGTATCCCTTTTTCTGGGTACTTGCGGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGAACAACATCTCAATCTCATCGAGATGTTGGACATGAAGGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GGTGTGGCAAAGCGATGGTTTGATTGGCGTGCTGAAACT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTTATGAGGAGGGCCGAACAAATCCTAAAATCCTTTTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGACATTAAAGTCATAGCAAAAGGGGTGAAGTACGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAACACGATTGGGACTATTTGATCTTCTGGATCAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGTTCACCACTCGTCTCGATTGCGACTCTGTCGCT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GAGCATTCAAATTATGGCAACAGCAGAGATCCGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ACTTTCGGGGAATAACCCCCCCCTTTAAAAAGCAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGCAACGGTAGCCATCTATCAAAATGACTATCGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AATCAAAGAAGCCTTTGAAGAAGGCGATTTTGACT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGCGTGCAAACAAATCATATGCGGCGAGCAGTGTGGTATTTAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GTGGCTCGGTTGATGACAGGGGGTACTTACATG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCGAGTTGGGTGAAAACCTCGCTGGCTCCTGGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CAAGAAAAGCCCTGCCTCTGTAATCCAGCGGGAGGGTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TCATTTCCAGCTTCGTGACTGGGGACTGCGTGAGTTGGACTAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGAAATCGTTAAATCTTTGGAGGAATTTTTATGCCTCCAA


>CP020664|5|1|1490992-1491539|PILER-CR
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TCGTGACTATGCGACAGGTGAATGGGTTGCATTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGAAATAGAATTCTTGGCGCAAGTTAAGGAAGTCATC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTGTGCCTTCGGTCCCATTGGAGTGATTTACCTTTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TAAACGTACAGGGGGAATTTGTGCATTTCGCATGAGTTTAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAAACTACTCGAAACCTTCGCTCAATGGTTCGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CGTAACCCAAAAAGAACAAACCGTAAAAGTATTTGACATCAAGCG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ACAAATGCAGTCAATGCAGTCATAGAAATTTATGTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATTTTAAAAAAAATGTCTAAAATGTCTAAACCGCCTATTGAGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGATGTCTCTCAAGTTGCTGGCTTGGCACACCGACCCAGCTGATCTTCCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AATATTCTGCGGAAAAGACGCCACAAACCTACCAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTCTCGCAGAAACCTTATACCGTCTGAAATCAGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTACGGGCATTAGTTGTCCCAAGAGAGGGGCTTTGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTAACCTGGATCTTTTCAGTGGTGTTCGGGGCATCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGGAGGTTACAGGGGTATGCATCGTAGGGGAGGAAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCCTCGGCTTTCGAGATCTCCTTCCCTGCCGCTGACTCCAGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTTAAAAATGCCGCAGGTGATTCGGCCTCTGACGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CAGAGGGATTATCACGGTGAGTAGTAAGGATGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTTGTGAGACAATACAAAAAGTACTGACACCGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGCTACCTTACGACGATTATTGAGGACTACCTAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCGGAGGTGGATCGCCTCCGAGATGAAGTGGCCACAAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTGCTAGAGGAGTTTTTAGAGCTCCTACAAGTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAATGTTGTTATTCTTCAAGGATAGCAACATCACC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGCGCCAAGCTCAAAGAAATCGCCACTGTTCTGCACGAATT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAGAAAGAAGCGCGTGCTGCTTTCTACTTTGTGAGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATAGTTTCAATCCGTTCCGTGAGTTACAACGCGCTCGAATCCTGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGGGATTGTTCGCCTGCGAACAGCAGACCCCAAAAGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGTGCACCCCTTCTTGGTGCTTGCGAGGAGCCTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAGCCCAGCTCCGCGCTGAGGAAGTATTCTGCCTAAAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAGTGCATTGGAAACGTTAGCTTTACAAACTGTCTCGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGATCATTTCAAAGAGTAAAGCCACGGTGGCGATCTCTCCAGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGGAGTATTTTTTGGGTTTCTATTCTGGGTAGACTTCTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGGTTTGCAACAGCCTTGACTTCCATGATGGTGTTTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAACATCCTTCTCCAAGAGGAGTTGGAAAAGAAGAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGTCCCCGAGGGCAAGATCCTTTTGCGTCACTATATGAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCTTGAACGAAGCTCCCCAGCTTCTGGGTGACGTCCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGGATCATCAGGCCGCCCATGCTGGTGACCATGTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGATGGCAAGTCCGTGAAGGTTTCGGGAGACTCTGTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTATTTGACAAGCCCACCATAGCCTGTGCACTTCGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GGGGAAATCTAATAGACTACCTCGTAGTGGTCTATG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGGCACAAACCATCCTTTACGCCGGCCAACTGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTCGAGTGAAATTGTGCTGTTGCGTAAAGTGCTGGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCTTAAAATGCGTAACCTTTTCCCCGAGGCTACACCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATGAATTTTTTGTTTGTCAAAAACTTTTTTTGATAAACTCAGCCCCAACACCCCTAAAAAGGTGCGACGGCGATACATCAGAAGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCTGAAATTCAGATCAAAATCATCGCCGCGATTGTTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGCTTGAGTTTGTGGGTATCCCTTTTTCTGGGTACTTGCGGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAGAACAACATCTCAATCTCATCGAGATGTTGGACATGAAGGGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GGTGTGGCAAAGCGATGGTTTGATTGGCGTGCTGAAACT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTTATGAGGAGGGCCGAACAAATCCTAAAATCCTTTTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGACATTAAAGTCATAGCAAAAGGGGTGAAGTACGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAACACGATTGGGACTATTTGATCTTCTGGATCAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGTTCACCACTCGTCTCGATTGCGACTCTGTCGCT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GAGCATTCAAATTATGGCAACAGCAGAGATCCGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ACTTTCGGGGAATAACCCCCCCCTTTAAAAAGCAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGCAACGGTAGCCATCTATCAAAATGACTATCGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAATCAAAGAAGCCTTTGAAGAAGGCGATTTTGACTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGCGTGCAAACAAATCATATGCGGCGAGCAGTGTGGTATTTAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GTGGCTCGGTTGATGACAGGGGGTACTTACATG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCGAGTTGGGTGAAAACCTCGCTGGCTCCTGGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CAAGAAAAGCCCTGCCTCTGTAATCCAGCGGGAGGGTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TCATTTCCAGCTTCGTGACTGGGGACTGCGTGAGTTGGACTAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGAAATCGTTAAATCTTTGGAGGAATTTTTATGCCTCCAA


>CP020664|5|2|1491666-1494025|PILER-CR
	TCGTGACTATGCGACAGGTGAATGGGTTGCATTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGAAATAGAATTCTTGGCGCAAGTTAAGGAAGTCATC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTGTGCCTTCGGTCCCATTGGAGTGATTTACCTTTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TAAACGTACAGGGGGAATTTGTGCATTTCGCATGAGTTTAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAAACTACTCGAAACCTTCGCTCAATGGTTCGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CGTAACCCAAAAAGAACAAACCGTAAAAGTATTTGACATCAAGCG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ACAAATGCAGTCAATGCAGTCATAGAAATTTATGTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATTTTAAAAAAAATGTCTAAAATGTCTAAACCGCCTATTGAGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGATGTCTCTCAAGTTGCTGGCTTGGCACACCGACCCAGCTGATCTTCCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AATATTCTGCGGAAAAGACGCCACAAACCTACCAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTCTCGCAGAAACCTTATACCGTCTGAAATCAGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTACGGGCATTAGTTGTCCCAAGAGAGGGGCTTTGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTAACCTGGATCTTTTCAGTGGTGTTCGGGGCATCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGGAGGTTACAGGGGTATGCATCGTAGGGGAGGAAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCCTCGGCTTTCGAGATCTCCTTCCCTGCCGCTGACTCCAGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTTAAAAATGCCGCAGGTGATTCGGCCTCTGACGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CAGAGGGATTATCACGGTGAGTAGTAAGGATGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTTGTGAGACAATACAAAAAGTACTGACACCGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGCTACCTTACGACGATTATTGAGGACTACCTAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCGGAGGTGGATCGCCTCCGAGATGAAGTGGCCACAAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTGCTAGAGGAGTTTTTAGAGCTCCTACAAGTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAATGTTGTTATTCTTCAAGGATAGCAACATCACC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGCGCCAAGCTCAAAGAAATCGCCACTGTTCTGCACGAATT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAGAAAGAAGCGCGTGCTGCTTTCTACTTTGTGAGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATAGTTTCAATCCGTTCCGTGAGTTACAACGCGCTCGAATCCTGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGGGATTGTTCGCCTGCGAACAGCAGACCCCAAAAGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGTGCACCCCTTCTTGGTGCTTGCGAGGAGCCTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAGCCCAGCTCCGCGCTGAGGAAGTATTCTGCCTAAAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAGTGCATTGGAAACGTTAGCTTTACAAACTGTCTCGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGATCATTTCAAAGAGTAAAGCCACGGTGGCGATCTCTCCAGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGGAGTATTTTTTGGGTTTCTATTCTGGGTAGACTTCTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGGTTTGCAACAGCCTTGACTTCCATGATGGTGTTTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAACATCCTTCTCCAAGAGGAGTTGGAAAAGAAGAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGTCCCCGAGGGCAAGATCCTTTTGCGTCACTATATGAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCTTGAACGAAGCTCCCCAGCTTCTGGGTGACGTCCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGGATCATCAGGCCGCCCATGCTGGTGACCATGTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGATGGCAAGTCCGTGAAGGTTTCGGGAGACTCTGTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTATTTGACAAGCCCACCATAGCCTGTGCACTTCGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GGGGAAATCTAATAGACTACCTCGTAGTGGTCTATG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGGCACAAACCATCCTTTACGCCGGCCAACTGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTCGAGTGAAATTGTGCTGTTGCGTAAAGTGCTGGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCTTAAAATGCGTAACCTTTTCCCCGAGGCTACACCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATGAATTTTTTGTTTGTCAAAAACTTTTTTTGATAAACTCAGCCCCAACACCCCTAAAAAGGTGCGACGGCGATACATCAGAAGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCTGAAATTCAGATCAAAATCATCGCCGCGATTGTTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGCTTGAGTTTGTGGGTATCCCTTTTTCTGGGTACTTGCGGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAGAACAACATCTCAATCTCATCGAGATGTTGGACATGAAGGGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GGTGTGGCAAAGCGATGGTTTGATTGGCGTGCTGAAACT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTTATGAGGAGGGCCGAACAAATCCTAAAATCCTTTTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGACATTAAAGTCATAGCAAAAGGGGTGAAGTACGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAACACGATTGGGACTATTTGATCTTCTGGATCAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGTTCACCACTCGTCTCGATTGCGACTCTGTCGCT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GAGCATTCAAATTATGGCAACAGCAGAGATCCGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ACTTTCGGGGAATAACCCCCCCCTTTAAAAAGCAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGCAACGGTAGCCATCTATCAAAATGACTATCGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAATCAAAGAAGCCTTTGAAGAAGGCGATTTTGACTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGCGTGCAAACAAATCATATGCGGCGAGCAGTGTGGTATTTAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GTGGCTCGGTTGATGACAGGGGGTACTTACATG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCGAGTTGGGTGAAAACCTCGCTGGCTCCTGGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CAAGAAAAGCCCTGCCTCTGTAATCCAGCGGGAGGGTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TCATTTCCAGCTTCGTGACTGGGGACTGCGTGAGTTGGACTAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGAAATCGTTAAATCTTTGGAGGAATTTTTATGCCTCCAA


>CP020664|5|3|1494180-1495522|CRT
	AGTTTACACAATAAAAAAAGGAGAAAATTATGCGCCTTACTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TCGTGACTATGCGACAGGTGAATGGGTTGCATTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGAAATAGAATTCTTGGCGCAAGTTAAGGAAGTCATC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTGTGCCTTCGGTCCCATTGGAGTGATTTACCTTTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TAAACGTACAGGGGGAATTTGTGCATTTCGCATGAGTTTAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAAACTACTCGAAACCTTCGCTCAATGGTTCGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CGTAACCCAAAAAGAACAAACCGTAAAAGTATTTGACATCAAGCG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ACAAATGCAGTCAATGCAGTCATAGAAATTTATGTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTTTAAAAAAAATGTCTAAAATGTCTAAACCGCCTATTGAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GATGTCTCTCAAGTTGCTGGCTTGGCACACCGACCCAGCTGATCTTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AATATTCTGCGGAAAAGACGCCACAAACCTACCAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTCTCGCAGAAACCTTATACCGTCTGAAATCAGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTACGGGCATTAGTTGTCCCAAGAGAGGGGCTTTGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTAACCTGGATCTTTTCAGTGGTGTTCGGGGCATCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGGAGGTTACAGGGGTATGCATCGTAGGGGAGGAAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCCTCGGCTTTCGAGATCTCCTTCCCTGCCGCTGACTCCAGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTTAAAAATGCCGCAGGTGATTCGGCCTCTGACGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CAGAGGGATTATCACGGTGAGTAGTAAGGATGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTTGTGAGACAATACAAAAAGTACTGACACCGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGCTACCTTACGACGATTATTGAGGACTACCTAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCGGAGGTGGATCGCCTCCGAGATGAAGTGGCCACAAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTGCTAGAGGAGTTTTTAGAGCTCCTACAAGTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAATGTTGTTATTCTTCAAGGATAGCAACATCACC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGCGCCAAGCTCAAAGAAATCGCCACTGTTCTGCACGAATT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAGAAAGAAGCGCGTGCTGCTTTCTACTTTGTGAGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATAGTTTCAATCCGTTCCGTGAGTTACAACGCGCTCGAATCCTGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGGGATTGTTCGCCTGCGAACAGCAGACCCCAAAAGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGTGCACCCCTTCTTGGTGCTTGCGAGGAGCCTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAGCCCAGCTCCGCGCTGAGGAAGTATTCTGCCTAAAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAGTGCATTGGAAACGTTAGCTTTACAAACTGTCTCGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGATCATTTCAAAGAGTAAAGCCACGGTGGCGATCTCTCCAGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGGAGTATTTTTTGGGTTTCTATTCTGGGTAGACTTCTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGGTTTGCAACAGCCTTGACTTCCATGATGGTGTTTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAACATCCTTCTCCAAGAGGAGTTGGAAAAGAAGAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGTCCCCGAGGGCAAGATCCTTTTGCGTCACTATATGAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCTTGAACGAAGCTCCCCAGCTTCTGGGTGACGTCCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGGATCATCAGGCCGCCCATGCTGGTGACCATGTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGATGGCAAGTCCGTGAAGGTTTCGGGAGACTCTGTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTATTTGACAAGCCCACCATAGCCTGTGCACTTCGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GGGGAAATCTAATAGACTACCTCGTAGTGGTCTATG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGGCACAAACCATCCTTTACGCCGGCCAACTGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTCGAGTGAAATTGTGCTGTTGCGTAAAGTGCTGGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CTTAAAATGCGTAACCTTTTCCCCGAGGCTACACC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATGAATTTTTTGTTTGTCAAAAACTTTTTTTGATAAACTCAGCCCCAACACCCCTAAAAAGGTGCGACGGCGATACATCAGAAGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CTGAAATTCAGATCAAAATCATCGCCGCGATTGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTTGAGTTTGTGGGTATCCCTTTTTCTGGGTACTTGCGGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGAACAACATCTCAATCTCATCGAGATGTTGGACATGAAGGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GGTGTGGCAAAGCGATGGTTTGATTGGCGTGCTGAAACT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTTATGAGGAGGGCCGAACAAATCCTAAAATCCTTTTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGACATTAAAGTCATAGCAAAAGGGGTGAAGTACGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAACACGATTGGGACTATTTGATCTTCTGGATCAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGTTCACCACTCGTCTCGATTGCGACTCTGTCGCT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GAGCATTCAAATTATGGCAACAGCAGAGATCCGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ACTTTCGGGGAATAACCCCCCCCTTTAAAAAGCAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGCAACGGTAGCCATCTATCAAAATGACTATCGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AATCAAAGAAGCCTTTGAAGAAGGCGATTTTGACT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGCGTGCAAACAAATCATATGCGGCGAGCAGTGTGGTATTTAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GTGGCTCGGTTGATGACAGGGGGTACTTACATG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCGAGTTGGGTGAAAACCTCGCTGGCTCCTGGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CAAGAAAAGCCCTGCCTCTGTAATCCAGCGGGAGGGTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TCATTTCCAGCTTCGTGACTGGGGACTGCGTGAGTTGGACTAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGAAATCGTTAAATCTTTGGAGGAATTTTTATGCCTCCAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG

>CP020664|5|3|1494404-1495010|PILER-CR
	TCGTGACTATGCGACAGGTGAATGGGTTGCATTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGAAATAGAATTCTTGGCGCAAGTTAAGGAAGTCATC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTGTGCCTTCGGTCCCATTGGAGTGATTTACCTTTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TAAACGTACAGGGGGAATTTGTGCATTTCGCATGAGTTTAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAAACTACTCGAAACCTTCGCTCAATGGTTCGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CGTAACCCAAAAAGAACAAACCGTAAAAGTATTTGACATCAAGCG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ACAAATGCAGTCAATGCAGTCATAGAAATTTATGTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATTTTAAAAAAAATGTCTAAAATGTCTAAACCGCCTATTGAGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGATGTCTCTCAAGTTGCTGGCTTGGCACACCGACCCAGCTGATCTTCCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AATATTCTGCGGAAAAGACGCCACAAACCTACCAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTCTCGCAGAAACCTTATACCGTCTGAAATCAGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTACGGGCATTAGTTGTCCCAAGAGAGGGGCTTTGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTAACCTGGATCTTTTCAGTGGTGTTCGGGGCATCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGGAGGTTACAGGGGTATGCATCGTAGGGGAGGAAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCCTCGGCTTTCGAGATCTCCTTCCCTGCCGCTGACTCCAGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTTAAAAATGCCGCAGGTGATTCGGCCTCTGACGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CAGAGGGATTATCACGGTGAGTAGTAAGGATGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTTGTGAGACAATACAAAAAGTACTGACACCGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGCTACCTTACGACGATTATTGAGGACTACCTAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCGGAGGTGGATCGCCTCCGAGATGAAGTGGCCACAAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTGCTAGAGGAGTTTTTAGAGCTCCTACAAGTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAATGTTGTTATTCTTCAAGGATAGCAACATCACC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGCGCCAAGCTCAAAGAAATCGCCACTGTTCTGCACGAATT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAGAAAGAAGCGCGTGCTGCTTTCTACTTTGTGAGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATAGTTTCAATCCGTTCCGTGAGTTACAACGCGCTCGAATCCTGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGGGATTGTTCGCCTGCGAACAGCAGACCCCAAAAGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGTGCACCCCTTCTTGGTGCTTGCGAGGAGCCTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAGCCCAGCTCCGCGCTGAGGAAGTATTCTGCCTAAAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAGTGCATTGGAAACGTTAGCTTTACAAACTGTCTCGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGATCATTTCAAAGAGTAAAGCCACGGTGGCGATCTCTCCAGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGGAGTATTTTTTGGGTTTCTATTCTGGGTAGACTTCTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGGTTTGCAACAGCCTTGACTTCCATGATGGTGTTTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAACATCCTTCTCCAAGAGGAGTTGGAAAAGAAGAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGTCCCCGAGGGCAAGATCCTTTTGCGTCACTATATGAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCTTGAACGAAGCTCCCCAGCTTCTGGGTGACGTCCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGGATCATCAGGCCGCCCATGCTGGTGACCATGTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGATGGCAAGTCCGTGAAGGTTTCGGGAGACTCTGTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTATTTGACAAGCCCACCATAGCCTGTGCACTTCGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GGGGAAATCTAATAGACTACCTCGTAGTGGTCTATG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGGCACAAACCATCCTTTACGCCGGCCAACTGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTCGAGTGAAATTGTGCTGTTGCGTAAAGTGCTGGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCTTAAAATGCGTAACCTTTTCCCCGAGGCTACACCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATGAATTTTTTGTTTGTCAAAAACTTTTTTTGATAAACTCAGCCCCAACACCCCTAAAAAGGTGCGACGGCGATACATCAGAAGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCTGAAATTCAGATCAAAATCATCGCCGCGATTGTTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGCTTGAGTTTGTGGGTATCCCTTTTTCTGGGTACTTGCGGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAGAACAACATCTCAATCTCATCGAGATGTTGGACATGAAGGGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GGTGTGGCAAAGCGATGGTTTGATTGGCGTGCTGAAACT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTTATGAGGAGGGCCGAACAAATCCTAAAATCCTTTTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGACATTAAAGTCATAGCAAAAGGGGTGAAGTACGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAACACGATTGGGACTATTTGATCTTCTGGATCAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGTTCACCACTCGTCTCGATTGCGACTCTGTCGCT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GAGCATTCAAATTATGGCAACAGCAGAGATCCGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ACTTTCGGGGAATAACCCCCCCCTTTAAAAAGCAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGCAACGGTAGCCATCTATCAAAATGACTATCGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAATCAAAGAAGCCTTTGAAGAAGGCGATTTTGACTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGCGTGCAAACAAATCATATGCGGCGAGCAGTGTGGTATTTAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GTGGCTCGGTTGATGACAGGGGGTACTTACATG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCGAGTTGGGTGAAAACCTCGCTGGCTCCTGGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CAAGAAAAGCCCTGCCTCTGTAATCCAGCGGGAGGGTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TCATTTCCAGCTTCGTGACTGGGGACTGCGTGAGTTGGACTAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGAAATCGTTAAATCTTTGGAGGAATTTTTATGCCTCCAA


>CP020664|5|4|1495046-1495522|PILER-CR
	TCGTGACTATGCGACAGGTGAATGGGTTGCATTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGAAATAGAATTCTTGGCGCAAGTTAAGGAAGTCATC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTGTGCCTTCGGTCCCATTGGAGTGATTTACCTTTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TAAACGTACAGGGGGAATTTGTGCATTTCGCATGAGTTTAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAAACTACTCGAAACCTTCGCTCAATGGTTCGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CGTAACCCAAAAAGAACAAACCGTAAAAGTATTTGACATCAAGCG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ACAAATGCAGTCAATGCAGTCATAGAAATTTATGTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATTTTAAAAAAAATGTCTAAAATGTCTAAACCGCCTATTGAGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGATGTCTCTCAAGTTGCTGGCTTGGCACACCGACCCAGCTGATCTTCCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AATATTCTGCGGAAAAGACGCCACAAACCTACCAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTCTCGCAGAAACCTTATACCGTCTGAAATCAGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTACGGGCATTAGTTGTCCCAAGAGAGGGGCTTTGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTAACCTGGATCTTTTCAGTGGTGTTCGGGGCATCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGGAGGTTACAGGGGTATGCATCGTAGGGGAGGAAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCCTCGGCTTTCGAGATCTCCTTCCCTGCCGCTGACTCCAGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTTAAAAATGCCGCAGGTGATTCGGCCTCTGACGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CAGAGGGATTATCACGGTGAGTAGTAAGGATGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCTTGTGAGACAATACAAAAAGTACTGACACCGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGCTACCTTACGACGATTATTGAGGACTACCTAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GCGGAGGTGGATCGCCTCCGAGATGAAGTGGCCACAAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATTGCTAGAGGAGTTTTTAGAGCTCCTACAAGTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAATGTTGTTATTCTTCAAGGATAGCAACATCACC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAGCGCCAAGCTCAAAGAAATCGCCACTGTTCTGCACGAATT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAGAAAGAAGCGCGTGCTGCTTTCTACTTTGTGAGTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATAGTTTCAATCCGTTCCGTGAGTTACAACGCGCTCGAATCCTGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGGGATTGTTCGCCTGCGAACAGCAGACCCCAAAAGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGTGCACCCCTTCTTGGTGCTTGCGAGGAGCCTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAGCCCAGCTCCGCGCTGAGGAAGTATTCTGCCTAAAGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAGTGCATTGGAAACGTTAGCTTTACAAACTGTCTCGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGATCATTTCAAAGAGTAAAGCCACGGTGGCGATCTCTCCAGG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGGAGTATTTTTTGGGTTTCTATTCTGGGTAGACTTCTCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGGTTTGCAACAGCCTTGACTTCCATGATGGTGTTTT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAACATCCTTCTCCAAGAGGAGTTGGAAAAGAAGAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGTCCCCGAGGGCAAGATCCTTTTGCGTCACTATATGAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCTTGAACGAAGCTCCCCAGCTTCTGGGTGACGTCCC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGGATCATCAGGCCGCCCATGCTGGTGACCATGTGAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGATGGCAAGTCCGTGAAGGTTTCGGGAGACTCTGTC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTATTTGACAAGCCCACCATAGCCTGTGCACTTCGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GGGGAAATCTAATAGACTACCTCGTAGTGGTCTATG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTGGCACAAACCATCCTTTACGCCGGCCAACTGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTCGAGTGAAATTGTGCTGTTGCGTAAAGTGCTGGT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCTTAAAATGCGTAACCTTTTCCCCGAGGCTACACCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGATGAATTTTTTGTTTGTCAAAAACTTTTTTTGATAAACTCAGCCCCAACACCCCTAAAAAGGTGCGACGGCGATACATCAGAAGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGCTGAAATTCAGATCAAAATCATCGCCGCGATTGTTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGGCTTGAGTTTGTGGGTATCCCTTTTTCTGGGTACTTGCGGCGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAAGAACAACATCTCAATCTCATCGAGATGTTGGACATGAAGGGGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GGTGTGGCAAAGCGATGGTTTGATTGGCGTGCTGAAACT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TTTTATGAGGAGGGCCGAACAAATCCTAAAATCCTTTTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGACATTAAAGTCATAGCAAAAGGGGTGAAGTACGAG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AAAAACACGATTGGGACTATTTGATCTTCTGGATCAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TGTTCACCACTCGTCTCGATTGCGACTCTGTCGCT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GAGCATTCAAATTATGGCAACAGCAGAGATCCGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ACTTTCGGGGAATAACCCCCCCCTTTAAAAAGCAAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	AGCAACGGTAGCCATCTATCAAAATGACTATCGA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAGAATCAAAGAAGCCTTTGAAGAAGGCGATTTTGACTGTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGCGTGCAAACAAATCATATGCGGCGAGCAGTGTGGTATTTAC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	GTGGCTCGGTTGATGACAGGGGGTACTTACATG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CCGAGTTGGGTGAAAACCTCGCTGGCTCCTGGC
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	CAAGAAAAGCCCTGCCTCTGTAATCCAGCGGGAGGGTG
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	TCATTTCCAGCTTCGTGACTGGGGACTGCGTGAGTTGGACTAT
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG	ATGAAATCGTTAAATCTTTGGAGGAATTTTTATGCCTCCAA
GTTTCCATTAATTAAACTTGCTAAGAAGTTAAAAG

Protein	Signature genes	Signature genes Name	Protein_function
CP020664.1\|AVQ71194.1\|1499209_1499410_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71197.1\|1504863_1505826_-\|NYN-domain-containing-protein	unknown	unknown	gnl\|CDD\|350235
CP020664.1\|AVQ71191.1\|1497628_1498276_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366676
CP020664.1\|AVQ71180.1\|1474011_1475688_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|199892
CP020664.1\|AVQ71184.1\|1486159_1487401_+\|CRISPR-associated-protein	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	gnl\|CDD\|187879
CP020664.1\|AVQ71193.1\|1498760_1499213_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71183.1\|1483171_1486153_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|378863
CP020664.1\|AVQ71192.1\|1498262_1498730_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367615
CP020664.1\|AVQ71182.1\|1480027_1482160_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376917
CP020664.1\|AVQ71188.1\|1496134_1496743_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71195.1\|1499665_1502110_-\|hypothetical-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379324
CP020664.1\|AVQ71190.1\|1497045_1497627_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71196.1\|1503088_1504789_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71185.1\|1487397_1488315_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl\|CDD\|274210
CP020664.1\|AVQ71181.1\|1475811_1480005_+\|type-IV-secretion-protein-Rhs	unknown	unknown	gnl\|CDD\|238121
CP020664.1\|AVQ71179.1\|1472601_1473921_+\|alpha-amylase	unknown	unknown	gnl\|CDD\|200454
CP020664.1\|AVQ71187.1\|1488703_1490590_+\|CRISPR-associated-protein-Cmr6	csm3gr7	pfam03787_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|213662
CP020664.1\|AVQ71189.1\|1496739_1497036_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71186.1\|1488311_1488707_+\|hypothetical-protein	cmr5gr11	cls000022_cmr5gr11_CAS-III-B	unknown
CP020664.1\|AVQ71178.1\|1470932_1472525_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238153

Protein	Function_ID	Function_description	E-value
CP020664.1\|AVQ71197.1\|1504863_1505826_-\|NYN-domain-containing-protein	gnl\|CDD\|350235	cd10911, PIN_LabA, PIN domain of Synechococcus elongatus LabA (low-amplitude and bright) and related proteins. This subfamily contains Synechococcus elongatus PCC 7942 LabA which participates in cyanobacterial circadian timing, it is required for negative feedback regulation of the autokinase/autophosphatase KaiC, a central component of the circadian clock system, and appears to be necessary for KaiC-dependent repression of gene expression. This subfamily belongs to the LabA-like domain family which includes the N-terminal domain of limkain b1, a human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes. Also included in the LabA-like domain family are human ZNF451, uncharacterized Bacillus subtilis YqxD, uncharacterized Escherichia coli YaiI, and the N-terminal domain of a well-conserved group of mainly bacterial proteins with no defined function, which contain a C-terminal LabA_like_C domain. Curiously Pseudomonas putida S16 NicB , which is described as a putative NADH-dependent hydroxylase involved in the microbial degradation of nicotine also falls into the LabA-like family. The PIN (PilT N terminus) domain belongs to a large nuclease superfamily. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.9159e-27
CP020664.1\|AVQ71180.1\|1474011_1475688_+\|hypothetical-protein	gnl\|CDD\|199892	cd07184, E_set_Isoamylase_like_N, N-terminal Early set domain associated with the catalytic domain of isoamylase-like (also called glycogen 6-glucanohydrolase) proteins. E or "early" set domains are associated with the catalytic domain of isoamylase-like proteins at the N-terminal end. Isoamylase is one of the starch-debranching enzymes that catalyze the hydrolysis of alpha-1,6-glucosidic linkages specific in alpha-glucans such as amylopectin or glycogen. Isoamylase contains a bound calcium ion, but this is not in the same position as the conserved calcium ion that has been reported in other alpha-amylase family enzymes. The N-terminal domain of isoamylase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase. This domain is also a member of the CBM48 (Carbohydrate Binding Module 48) family whose members include pullulanase, maltooligosyl trehalose synthase, starch branching enzyme, glycogen branching enzyme, glycogen debranching enzyme, and the beta subunit of AMP-activated protein kinase.	0.00425886
CP020664.1\|AVQ71184.1\|1486159_1487401_+\|CRISPR-associated-protein	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	3.59165e-38
CP020664.1\|AVQ71183.1\|1483171_1486153_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|378863	pfam12469, DUF3692, CRISPR-associated protein. This domain family is found in bacteria and archaea, and is typically between 101 and 138 amino acids in length. The proteins in this family are frequently annotated as CRISPR-associated proteins however there is little accompanying literature to confirm this.	2.80794e-36
CP020664.1\|AVQ71192.1\|1498262_1498730_+\|hypothetical-protein	gnl\|CDD\|367615	pfam03703, bPH_2, Bacterial PH domain. Domain found in uncharacterized family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices. Members of this family have a PH domain like structure.	6.39327e-08
CP020664.1\|AVQ71187.1\|1488703_1490590_+\|CRISPR-associated-protein-Cmr6	gnl\|CDD\|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	2.32774e-17
CP020664.1\|AVQ71182.1\|1480027_1482160_+\|hypothetical-protein	gnl\|CDD\|376917	pfam02743, dCache_1, Cache domain. Double cache domain 1 covers the last three strands from the membrane distal PAS-like domain, the first two strands of the membrane proximal domain, and the connecting elements between the two domains.	8.14063e-16
CP020664.1\|AVQ71185.1\|1487397_1488315_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	2.05083e-32
CP020664.1\|AVQ71181.1\|1475811_1480005_+\|type-IV-secretion-protein-Rhs	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	6.25927e-88
CP020664.1\|AVQ71179.1\|1472601_1473921_+\|alpha-amylase	gnl\|CDD\|200454	cd11315, AmyAc_bac1_AmyA, Alpha amylase catalytic domain found in bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase). AmyA (EC 3.2.1.1) catalyzes the hydrolysis of alpha-(1,4) glycosidic linkages of glycogen, starch, related polysaccharides, and some oligosaccharides. This group includes Firmicutes, Proteobacteria, Actinobacteria, and Cyanobacteria. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	3.04802e-122
CP020664.1\|AVQ71191.1\|1497628_1498276_+\|hypothetical-protein	gnl\|CDD\|366676	pfam01496, V_ATPase_I, V-type ATPase 116kDa subunit family. This family consists of the 116kDa V-type ATPase (vacuolar (H+)-ATPases) subunits, as well as V-type ATP synthase subunit i. The V-type ATPases family are proton pumps that acidify intracellular compartments in eukaryotic cells for example yeast central vacuoles, clathrin-coated and synaptic vesicles. They have important roles in membrane trafficking processes. The 116kDa subunit (subunit a) in the V-type ATPase is part of the V0 functional domain responsible for proton transport. The a subunit is a transmembrane glycoprotein with multiple putative transmembrane helices it has a hydrophilic amino terminal and a hydrophobic carboxy terminal. It has roles in proton transport and assembly of the V-type ATPase complex. This subunit is encoded by two homologous gene in yeast VPH1 and STV1.	0.00224355
CP020664.1\|AVQ71195.1\|1499665_1502110_-\|hypothetical-protein	gnl\|CDD\|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	2.58463e-22
CP020664.1\|AVQ71178.1\|1470932_1472525_+\|hypothetical-protein	gnl\|CDD\|238153	cd00249, AGE, AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is structurally and mechanistically distinct from the other four types of epimerases. The AGE domain monomer is composed of an alpha(6)/alpha(6)-barrel, the structure of which is also found in glucoamylase and cellulase. The active form is a homodimer. The alignment also contains subtype III mannose 6-phosphate isomerases.	1.9506e-10

>CP020664.1|AVQ71187.1|1488703_1490590_+|CRISPR-associated-protein-Cmr6
MTAQQEWQKFLKKLQKDKNPLYDLYKDSQLEIGTEITIYFSDEEAKKKASAKWQKLQAKFPPHWKNQKINFKVGQLAPSSITAMTRSTARTNNPTSRKLTSPLQALNHRLFNNNDTAKPVLIEAAAADKTCQSLYQQLTEKTKRLADETLTVEFIWRLRVGGMRGFQELLLPVFHPVYGVPYIPSSSLKGVVRAWARQHRPEAEVNRLLGTLEDGIGCVQFLDAFPTAPCLTVDIANPQWSWENNRVCYQPVPHYLLSMEEPEILIGLTRTSRGKLEDVSTVKDWLQLALSAGIGSRVSAGYGRTSVASSLSHHSSHAFKLWTQGIYGANPPAKDNQYQGNNEFRPVAVRGMLRYWFRAVGLSIYSPQQCKDLEGRLFGTIEPQAQEGLIRISVDWKEEKGDRNRPYFCEGNILLEAKNQDALNLAEKLLQLSSHLAGIGRGSRRSLHWNNTIGLRGCHWEIDTKKLPRNQELWQQFLREVRDSLLALQSAIGNPANCPPGNPGNRSQDVLNSQTQIYLISCPSLKYPGTVNNWQNEGLGLKVRGEGLDFLYSSGFKGVNQEGNGNANVGGRISQRGETASTPSYVLIKSNFPPQQKPYQTVTIFGVNQRDRATFIQQLNSLNPMQIQ
>CP020664.1|AVQ71186.1|1488311_1488707_+|hypothetical-protein
MKLDSRQFSKQAHNALVEIKSELAVNYHKKASGLVQGLSTYISTWGLHRLSGDMQKFLGGTAEDTRYKGKVYQKFLTKLKEFSEADFDVNDQGTLIHMPLRKYTALNHLAIKLAKEWSFWSPAVLGEAEQS
>CP020664.1|AVQ71185.1|1487397_1488315_+|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MNTYLTYLYLLTPLHTGGSADEGNLMGIAREVHTEFPYLPASSLRGKIRSALEPSNPQSEEEKALAKEVSQFFGQKIKDGQQPTEGEVWFAEATLLFFPIASLSHHLVWITCPLWLERWNRWLKNSPLTQLIQNCREQITEARPALVSFTPEPLYLQTAILQQNALGQLNTNDSNSLSQSLQNLTNANGMINQLLKKLVIVDDEDCIALVETGLQREVRVALNEGEKTVKGGSFRSEEAIPPETVLFFPWGMKPVKQTENTQNIRAKTSELLKNKLQFGGLEGLGRGWCDLKTIETTETTTGSQK
>CP020664.1|AVQ71184.1|1486159_1487401_+|CRISPR-associated-protein
MGEQQMYWYEIAPLDVLLFREAKPFSPGESAWAKGLFPPFPSTVFQALRSTLSKDVKDLDFIGPFLLSPQDRLCFPTPKDLVAVSWSKKSQPKDEETKEEEREEDNLEKQAPEWHRTLRLQPVDRTDKAWEHLLFDEAGLAPMVAPFRELVEEENRREFFCRPYPWITAEALSEYLQGKELKDPTQFQDDPWNVQIMPHIQMQADKRQVKDEDGYFTEVAIRLKPGWRLVAGISIKLGETVVRLGGEGHRAIVIPFTLSDADQTLLNPKTNTTGDFAYLLTPGLAVKEEAVYGVYPCDWQPILAGCVSDRPLLWGGVSQIRRKLVISFGKENQERTASQISSGSSSPNSEAKGDEEFALLPQRAFVPPGTVYIFNQIPSETEALLPKPESTGNWLTSFQKLNYGKLLWGNTPL
>CP020664.1|AVQ71183.1|1483171_1486153_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MIMPESESPINSKNFYSRKLCALLEDKSILQQLQSIHPEELPLQIASSSDRVNLGEAQGTNINSVKHPISGQTRNITSQDLRPEIPAEITSETDIEKLFWWFWRFYPELIRQNQNDFFLYPAHSILPDCPLHSYKSTVSALVGAMYPEHWQEGGKSQHPYLFLFTFSPVQEFIKASRKFVDFWAGSYLLHYLSVKLCWYIAETYGSDAVITPSLWSQEIIDALIIKKYPDFAANFASFQDGTSPVGRFDNGISTSLSTAGFPNVIMALVPGKEAARELGEKLKKCLIKEWSEIAKKVREDIKKRTLEFLKDTKNQQKIDEILLKEFLSEQEICKRDLKKWQIGHHGSCWEWNKLWEAQIDKTWETYWTAMPLGNPEQPLTINPTEENYQQWKQAQNAIAPPHLAESLPTTAEENLYEQINTGTWWGALQARLGQSTQAVKNTRTWAIPTAPGERSTLSGQFSAVHPQLHYHGQFKNGGGLSARSMGLFWRLMAEVYPGLFNGSEKLNAIELTKRMAWRYGGVAESLGINLGQEDDTNYDNLIRFPNLSSIAAARFAYEDFKKGGQKTRNYWNCLNTLINQQLPNKADTFASRTRGRPYQISKVDRQINPENRNGQNFNGVMFSSKWLADDMNCNAQETATLRSLVEEAHKKAKFGEGSPADWWVIVLGDGDGMGKYVSGSKLKKYKEYLITDAIAENVKNHQDYPDLLATQKRMGPATHVGLNRALLDFSNRLVPYLTEERYCGKVVYSGGDDVMAVLPLADLPGYLRSLRAAWCADPDPEREFSTEGGYWTPKQSLQGLQKRPYFTMGDGATMSLGIVIAHKSVPLPTVLESLWTAEKDRAKKLYGKDGLCFRVIYGSGNTLEALMKGELLDLWWNFMQYDQQDLSALFYRLAEELPRHACVTESDRLLRKAAQVIINRRDQTLESHIQENLLNWLDQWENWAYQTYNQVNKNKTEKEVPLGTTEKDLANLLRFSAFWNNKRMQQMKWGETE
>CP020664.1|AVQ71182.1|1480027_1482160_+|hypothetical-protein
MQTQTNPWQKRIFRLSLSLCVISFLLATFTIYAYWREKNQTRETAKNNARQEAVRAAKEIDTQLRKLQNSANSIAHDISKGKLKDQQLLERLKSTIEQNPNWFGVGAAYTPYTYNSQMRLYAPYYIRKQGKLQLLQLESFYDYTQPGKGDRYIQSLASGSVWLEPYFGAATNTFLAEFGTPFYRLNPKTKKKIPSGVVFANYSLDGLKNLMNSLKLGKTGYGFILSKKGTLIYSPREDWVKEQKTIFQIISQGYKPEKLRVPAEKALKGSKIEMDFENPLTGQSSWIFFEPIPTTGWTLAAVFIQDEILVNTKSLHNKLILINLQIISFFFFLFILLFRAYKGSVRSLWAVSSSTSVVLLAGIGFIWYLQISEHKIEQKNNIVLLKKAGLNKFLRSRKSENPKDSPLYIPTGVFVQSLEFEDANDVFITGYIWQKYDKNIPQSVSRGFILPEAVDPNVTEIYRHQDQNFEVILWYFEAKLRENFDYSKYPFDVKDVWIRLWPKDFYKNIILTPDFDAYDLMIPTSLPGLAENFVLPGWDIKSSFFQYKLNNYNTNFGINSYIGQDNFPELYFTVIVQRNFINVLISNMMIIIVVLLLLFCIQILIIKHKESGENQDFTALEIVSACGAFLFIIIIDQINLRQKIVTAGIIYLDYFYFILYIMIILVAINAILFASNIKLDWIHYKNNLIPKLLYWPTNLALLLLVTLLVF
>CP020664.1|AVQ71181.1|1475811_1480005_+|type-IV-secretion-protein-Rhs
MKNFFDVFISYGRADSKAFAIKLNQRLAAEGLNVWFDQEDIPLAVDYQEQINDGIERTHNFIFIIAPHSVNSPYCLKEINLAIKYNKRIIPLLHVEQISQETWRQRNTDKTEADWQEYQAEGRHSSFPNMHPVIGKINWIYFREEIDDFESSFAGLISAIYQQQHYVENHSILLVKALNWLRNQQQTNYLLIGEERQAAEKWLKHRFTEEQPPCLPTDLHCEFISESSKNANNLMTQVFLSSSEKDNVIKEKIGKALMREGFTIWTNQTDIKTGTAFQEQINKGIEGADNFVYLISPEALQSSYCNLELAHAFATNKRIIPLLIEKTDIELIPSQLQKLQFIDLTEHEDRDKYRSSIDKLLRELNSDVAYYESHKVLLVKALKWQQQTHNPSVLFRGYNLQHFEAWLKVAKQRKESPPLPIQEEFIIASLNQHKPSSLEVFISYSRADSDLARRLNEALSSLGKLTWFDQESIASGEDFRREIYQGIEISDNFVFIISPQSINSPYCSDEVEYAQKLNKRIIPILHQKVAAKDLPAALASIQWLDFSQHGGDFLTNFTQLVRTIHTDRDHVHNHSKWLQRAKEWENSQENADLLLRGSEFVLAQTWLKKIEEQNKQPPATELHKEFIQASQTAIEAAETAEKERQQHLLKLQQERTQEVEKRLEQEKKNARRQKQLLIVVSLLGGVATCLGFFAAKEYRQAAISEIVAVGRTSQASFALNEQLEALTAAIKAKRLEIDLESRPFVNLPPKLKNNLKDILKIALYGIKQANIFSGHYGDVLGVKFSPDGEMIASASADNTLKLWKRDGSLLATLDEKRGGHKGSVNAVAFSPDGQLIASASTDKTIKLWKTDGTLLKTLKGHRDRVNAVAFSPDGQLIASAGNDTTVKLWKRDGTLLKTLKGNQNWSYVYTVAFSPDGQLIASGHRDKIIRIWRRDGTLLKTLEEHEGPVNLVVFSPDGQWIASGSYDKTLKLWKLDGTSPTITFYGQEDPIYGLTFTPDGEQIVSGSDDKTVRLWKLDGTLLMTLRGHSDAVNTVDVHNDGKNLQIASGSDDNEVRLWKPYNELATTLFGHSDVVSAIDWNADLIVSGSWDKTLKLWKRDGTLSTLLGHKGSVSSVKISPNGQFIVSGSPDGKVNIWRRDGKLLNSLKGGTGGINDLVISPDSKFIVSGNWDKTLKIWRRDGKLLNTLRGHTEVVETVAISPDGKFIASGSADNRIKIWRLDGHGTLISILTLKEHLSPILAIDFSPDGRMLVSGSGDNTIKLWKTDEKGQWLPSSVKTIEGHSNSVLDVKFSPDGQQIASASSDDTIKIWQLDGTLVNMLPGFGADVNAIHFSQDGKTLVSGSSNKTIIIWDLARHVTPKDIQRYACKWLKDYLQHNSEVTESDRRLCDRILDKDY
>CP020664.1|AVQ71180.1|1474011_1475688_+|hypothetical-protein
MAFFVVFVNPVKADVSNQVFSTPIVNQKTEGMAIPVLCNPDISQCPASAQLLGTVNNNRGHWNPFLPENNMIEDGPLYYKELELKANGGRHGNGIYAFRFVTNQNLQQTFKADHNRTDSTGKPKLVAGELAHQAQNIIIKVDRDDVYKISFNPSNLTFDVTPHPTYLTKIESVQLNGFVWDDEDMFQKFDETRANHEITKNGDWWEKTIPLKANGGIDFRADGVYQFLFSANHNEDWGFGAYNNGKNTLTGGTGFGSSGGQSRHSAITIQVFEDGNYTLQMNPLEYKFQVKAPEGVRPVKIWNDVNSFQLLGTFYPDVQFDPTKAEHNMEPVGDKIWTKTLQLKPGIYGANFAISGELFLDTMALGAWLESDHPNKLIGRGWHGKPNEPNIFFEVKETGAYRFTYDGAQDQFSIESLSNAPLQPPAVIETLQLVGNFPEPLQAWEPTSTANNMQQIGPHIFSKDVQLEANRKYEYKYNANNWGWLWVFADYELDGYGRDFLGRNPDPAHARIEDLKVYGQLTTHGNPPPLQFTPTASGWYTFTVNLETGAYSVQPSKK
>CP020664.1|AVQ71179.1|1472601_1473921_+|alpha-amylase
MAFFVVFVNPVRADVIYHAFNVPFREIERELPELKADGFTYIQISPPQLSNPSPEWWGRYQPIDFTVIDSPLGNENELKELIDTAHQQGEKIIVDVVLNHMANYENYPNTLQYPRFSPQDFHGRACIQNYDDSYQATHGWLGLDCASGQGGLPDLNTESSYVRQEAKNYINKLLDLGADGFRFDALKHIEPGFFQEVLAGVAADVYLYGEIVEDSPRMAFSYTSIHDLDVTDYPLLNTLKRAFSLGGDLRILKDPRSGNGALPGPNAVTFAKTHDTVPGSLLYGGYGLDSRDSILANAFVLSRADGLPLIYGEDASDPIVKAGVGFHEQMMGQPQSFPNGNEIATGGDSPNLLFIERGDLGIAMINKSGNPFDVADARMPGLDVGCYQELHYNFPMSVSVGGDGQKQITRWGNNERGGISIQPRDAMFFVKTSDNICVR
>CP020664.1|AVQ71178.1|1470932_1472525_+|hypothetical-protein
MLAQTQSWPTQITGKRIAIIVLAFLFSCGILVAYPSQVLADKNVNTVNVEQLLKLLPNGDRWKKHMTEELLPFWEMETALGQPLGNFPTYRCNDGSLYNSQSPCPELKYAAPGIVWVEPDYRDYVRAKSRQVYAYGVAFHVTGDETYLNYARAGANYLRKYALDSQNGGAYSYWHEPEHLPGPEKLQRTSQDLAYALSGMGFYYYLTRDAAVLKDIIQVKNYIFDTYYEPTLDLINWVKEPSPDGDQANQKELVSQLDQIYGYMLWLTPTLAEPDQTQWKQDLNHLAHIIINQFYSPQQNLFWGAVTNSNIKHLGTPHTDFGHSVKTMWLIYQIGKLTDDLELTLFGENHAAEILETAYLKKTGSWARGFDENGKIDPDKEWWSLAELDQVSATLGLVDPSYAVYLPKTYNYWFNYMVDPENKEIWHMVSAKTNKPYPCLATQPLNESKCFPKQHSWKNALHSFEHALVGYITMQQIHNQPVQLYYAFKEKPEDKFIYPYFYEGKVSQIINHSTQDNSSSIQEVIFTDIR
>CP020664.1|AVQ71188.1|1496134_1496743_+|hypothetical-protein
MTVSILIVLPSCSQKNPIALVLLKDTSISGQNNEEFKTTTKKACKGITESISRGDELKVIQVNGEQDFFEQLTPTNPTDAKKQCGAVRTTQKQGTLACPAVRTAHKIFQSSKKPGVLLVLIETNERESPCPQDWRTTVKNVIEKGGSVVILNATNNGGESFRLELETALEGLPVKYAHTDVEFAIKNAIEEARKQVRVEAKL
>CP020664.1|AVQ71189.1|1496739_1497036_+|hypothetical-protein
MKKSDSFPHFEGNGWNSSHVSNASGHTERESESNPWPESEARVNINQSKECHRLIAEDLHPQDQEDLLQRFPCYAIAQRRVAAAEFCRSQLIKIDELY
>CP020664.1|AVQ71190.1|1497045_1497627_+|hypothetical-protein
MDRGTFSSLKDNFFSLFATTIIAFLNFNTAMVLVPGDWDDIKIWFAIPVSLIACILFDNKVSEEYMRERLKGFAKATLNWINIQRERLTQTRLGSIRLETYIYLFQLFEAPFLETSVISIINRLGCIIYLITEFIVSAYLLLEREDLPWFMSIAPILAGLLNLATGILKGRLIVYPKALTQLRKKYQQYYEEV
>CP020664.1|AVQ71191.1|1497628_1498276_+|hypothetical-protein
MTIRLININEMNSQDLNELTTIYVSDASLSPSKMVEILQQRVACRSLHKSIKLIQEDHRRSFENCLSERDKKLEEIRKQAESLHSYPRAVNAPNPSYFLAINTVKEDLEFAEAQVRNHEKSISRLNNLELEFKSVLRTSSYWSGSLADSNKIEEILNEMGVKELMHDLEQRLRELQEQVKKFSLELTKFSIVTVYGESRVEDFQYQNGAAHHDIE
>CP020664.1|AVQ71192.1|1498262_1498730_+|hypothetical-protein
MTLNEYPFAASYAPRPEKPIVALKPKAWSVFLSWKNLRGIIFIIPLFSIAWQYLTLQRTEYMFTTQRFRTITGLFNQEIDEVWLFRVTDLRILKPFLYRLFGIANLYIYSTDRNNKLVVIQAISLTDALKLHEILQQQVNIERHRNRPDIPGSWQ
>CP020664.1|AVQ71193.1|1498760_1499213_+|hypothetical-protein
MADQNTSTNGETNTSCPSTIDSPELQDKDIWSSYDNPFGKYAFHGGMEGYLENKDPSPESPQQECFYDDSGNLIDENHQYAGMRGTANEYDGHKGDSSELWNHFYNDSGGIWQNGGEAFATSVESYYDSVEDYVSDVYDSVEDYVDDAFE
>CP020664.1|AVQ71194.1|1499209_1499410_+|hypothetical-protein
MKSKSKALERPQSSTAKRFYLLYSNPRQKARKTKKLRQQQMVNKQPKPVILQQNNATTTINNLVNS
>CP020664.1|AVQ71195.1|1499665_1502110_-|hypothetical-protein
MMKKLVICHFLIGLPASGKSTFAQVLAEEINAVVVSTDEIRAQLYGDAANQGIWADIEVEVLDQIKTAVEKDQPVIYDATNVMRPWRLDFLYKTVNLFNIQWIGWHLQTSVEKCKQRNQQRDRQVPDEVIDKMNANLQENPPESNEGLLKIYPVPVKDNNFDLDEICTILTGFKRLLANIANLNKNKVFHPYSRLLDFERLMHLMSVIINYPGIGNLAETEPENLKEILEVEELPQFSTSIEEICAVITKKYHAIYAHPEAIEKDLYWLEKNGILARGDIAADLVDIETIQVPDVMTHRYSNLEQFERLIKTIRFIVHRPFLNSPIKGTQKFFIENMLKLGLFDENKYNLYILRKDIEFVLNPYQILPEISMKKGYFAGTGILSQYELNKLYQSLRSHSVEKYFKDPLAAEIYDIFEQRLVNSKLLEEEAPYSTRLIGTKSIVDVEKYQQQFEQLEEAIKKGELLKFSHIQGSAKWPKDQPHFTAYPLQIVFHNIAWYLGYEIGEGDKKGLFAFARIDRIRFQQVNTQRDINEQKKALDKLHKLYDASAGIYLGDDVAKQRQYLDSQQGKKLNVTVILYATELAFKFICEGNQRFQKIEMSLPDWLKGTSYERKALATRDRGIFKLDQNIPPYQYTIKVTVPEWSLMDIDLIRWISGWGKEVKVIEPQSLVDRIYSIGEGITNIYQDIELICCDLEKVNDLVKNKEGSNYRFISIKTPNGNAEPQSVQSELNMNPGHIHPFIINDITQFNQEDIKKTVAFIKKKKKASKIVDGLRFLIYSHSGINLASEVAITIYRELKQDTELTNLRISLNYL
>CP020664.1|AVQ71196.1|1503088_1504789_+|hypothetical-protein
MTILLANLGTSDLSIKVTVDSKNYYLPIDFLSNESNLNKKLKDLDNDRRTIWDNMYQGFNYVPNSQVYQDLGLPNQKQPVRELTKALQSSYQKESPKWHSLIRPTRIGSVIQKAVAMGASKAYIFVTNQPTSHPQDTIYLFQIIQQWVQQEYPDFELIQKELQLNLDPQNPNLEDLVLEYYYNQLNEIYLEENLSQESTILVNVKGGTLHQKTALKIQAIASDFKNILFIDPILDLNQLLEGKNSECQLTSYWLYQRNQKYQTVKLLLQKRWDFDGARVIVKDWQETLIYLAKQVSAIASDTQKEQEKLTEILTRLDFAVSCFNLDKNAVRDNDKMEHNFWLNLYTQCRIYWELDEIANFLIRLSSFYEVTLNELIMGLRGQKYLRNNNQNQDWAFARNKASQEFYNKFQELEQDFERRDFYKLGNRYSKRNFVQTLIEIDHPERKALATRDRLELWQQILASLVKLDYWFDNRNALIHSGRGVSVQTMIDQLQEDKRNWTDDKDKYKANPHKACHPNNILGEVLNIAVHTYQLLGQKSSPYVGWDKNTPYYLYSELRDEICQQLI
>CP020664.1|AVQ71197.1|1504863_1505826_-|NYN-domain-containing-protein
MMKTFIQVASSLFVSAIVSSGQLDLMIVGTALATATSTSAIIVTKEKKKIKTLIEGSLTNSQTMIKGIEKIEKEVKAVTHTTEKVAKEVRTLKTNSRLLVGATQKVQHQQKLTTATLNQQQQQLNQLTPQEKPTPEIETEKRVIPLPQKRQTVTHIYIDGNNFSKTTETLGLEIDWKALKIALVEPAKQTDTFTLKYYTGLHEHLSPNQKQWLHHLKQLNYEVITFPLSQRENGWKTLGDDLAMGLDLIEAVKPGDRVILVTSDGDFIPLIERLQARNVDVNVVGASVNTNSRLQALLKQDFIPLESISDQIVKLKRLTA

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Crispr_ID: CP020664_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020664_6

1540134-1540234

TypeV

Consensus_repeat	Method
GACAGGCACTCATGCAAGAGGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020664_6

>merge|CP020664|6|1540134-1540234|CRISPRCasFinder
GACAGGCACTCATGCAAGAGGCACTCATGCAAAACGGAGAATAAATAAGTAGTCGTGCAAAATTAATTTCCTAGTGAAGATAGGCACTCATGCAAGAGGCA

>CP020664|6|6|1540134-1540234|CRISPRCasFinder
GACAGGCACTCATGCAAGAGGCA	CTCATGCAAAACGGAGAATAAATAAGTAGTCGTGCAAAATTAATTTCCTAGTGAA
GATAGGCACTCATGCAAGAGGCA

Protein	Signature genes	Signature genes Name	Protein_function
CP020664.1\|AVQ71224.1\|1538111_1538867_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|224057
CP020664.1\|AVQ71223.1\|1537292_1538111_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224596
CP020664.1\|AVQ71227.1\|1540866_1541907_+\|fatty-acid-desaturase	unknown	unknown	gnl\|CDD\|215323
CP020664.1\|AVQ71221.1\|1535309_1535810_-\|L,D-transpeptidase	unknown	unknown	gnl\|CDD\|341130
CP020664.1\|AVQ71226.1\|1540529_1540721_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71218.1\|1532770_1533484_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226983
CP020664.1\|AVQ71234.1\|1549623_1549884_-\|transposase	unknown	unknown	gnl\|CDD\|379129
CP020664.1\|AVQ71220.1\|1534929_1535184_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226580
CP020664.1\|AVQ71230.1\|1546382_1546577_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71231.1\|1546642_1547389_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372553
CP020664.1\|AVQ71225.1\|1539484_1539916_+\|DUF4278-domain-containing-protein	unknown	unknown	gnl\|CDD\|372912
CP020664.1\|AVQ71233.1\|1549220_1549475_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|280446
CP020664.1\|AVQ74255.1\|1531283_1531832_+\|response-regulator	unknown	unknown	gnl\|CDD\|381085
CP020664.1\|AVQ71228.1\|1542345_1543932_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
CP020664.1\|AVQ71219.1\|1533522_1534776_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226833
CP020664.1\|AVQ71235.1\|1550021_1550255_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71232.1\|1547429_1548848_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71217.1\|1531994_1532774_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|115718
CP020664.1\|AVQ71222.1\|1535974_1536850_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
CP020664.1\|AVQ71229.1\|1544392_1545883_-\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	unknown	unknown	gnl\|CDD\|234660

Protein	Function_ID	Function_description	E-value
CP020664.1\|AVQ71224.1\|1538111_1538867_+\|ATP-binding-protein	gnl\|CDD\|224057	COG1134, TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	2.73154e-107
CP020664.1\|AVQ71223.1\|1537292_1538111_+\|ABC-transporter-permease	gnl\|CDD\|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	1.38703e-57
CP020664.1\|AVQ71227.1\|1540866_1541907_+\|fatty-acid-desaturase	gnl\|CDD\|215323	PLN02598, PLN02598, omega-6 fatty acid desaturase.	1.89214e-156
CP020664.1\|AVQ71221.1\|1535309_1535810_-\|L,D-transpeptidase	gnl\|CDD\|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	3.62325e-44
CP020664.1\|AVQ71218.1\|1532770_1533484_-\|hypothetical-protein	gnl\|CDD\|226983	COG4636, Uma2, Endonuclease, Uma2 family (restriction endonuclease fold) [General function prediction only].	1.05485e-15
CP020664.1\|AVQ71234.1\|1549623_1549884_-\|transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.12972e-25
CP020664.1\|AVQ71220.1\|1534929_1535184_-\|hypothetical-protein	gnl\|CDD\|226580	COG4095, COG4095, Uncharacterized conserved protein [Function unknown].	2.51205e-15
CP020664.1\|AVQ71231.1\|1546642_1547389_+\|hypothetical-protein	gnl\|CDD\|372553	pfam13301, DUF4079, Protein of unknown function (DUF4079). This is an uncharacterized family of proteins.	2.48754e-45
CP020664.1\|AVQ71225.1\|1539484_1539916_+\|DUF4278-domain-containing-protein	gnl\|CDD\|372912	pfam14105, DUF4278, Domain of unknown function (DUF4278). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 58 and 136 amino acids in length. There is a single completely conserved residue R that may be functionally important.	2.83069e-06
CP020664.1\|AVQ74255.1\|1531283_1531832_+\|response-regulator	gnl\|CDD\|381085	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs). Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	2.21791e-21
CP020664.1\|AVQ71228.1\|1542345_1543932_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.56156e-63
CP020664.1\|AVQ71219.1\|1533522_1534776_-\|hypothetical-protein	gnl\|CDD\|226833	COG4398, COG4398, Uncharacterized protein conserved in bacteria [Function unknown].	1.36925e-159
CP020664.1\|AVQ71233.1\|1549220_1549475_-\|hypothetical-protein	gnl\|CDD\|280446	pfam02281, Dimer_Tnp_Tn5, Transposase Tn5 dimerization domain. Transposons are mobile DNA sequences capable of replication and insertion into the chromosome. Typically transposons code for the transposase enzyme, which catalyzes insertion, found between terminal inverted repeats. Tn5 has a unique method of self- regulation in which a truncated version of the transposase enzyme acts as an inhibitor. The catalytic domain of the Tn5 transposon is found in pfam01609. This domain mediates dimerization in the known structure.	7.1593e-11
CP020664.1\|AVQ71217.1\|1531994_1532774_+\|hypothetical-protein	gnl\|CDD\|115718	pfam07082, DUF1350, Protein of unknown function (DUF1350). This family consists of several hypothetical proteins from both cyanobacteria and plants. Members of this family are typically around 250 residues in length. The function of this family is unknown but the species distribution indicates that the family may be involved in photosynthesis.	2.29618e-136
CP020664.1\|AVQ71222.1\|1535974_1536850_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.57884e-103
CP020664.1\|AVQ71229.1\|1544392_1545883_-\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	gnl\|CDD\|234660	PRK00139, murE, UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional.	0

>CP020664.1|AVQ71225.1|1539484_1539916_+|DUF4278-domain-containing-protein
MSYLFLLPLFTAALAAYFWQKSSDEIAYLASAATVISLVLSLVLAPWQIQLLILLTVVIVVTFLWQGREEQKNVLVSTPETAGEKKYRGATYREPTVAEAPVKERGGKYRGAEVKITNNPRVANPIRSSSLKYRGAGSGNKDQ
>CP020664.1|AVQ71224.1|1538111_1538867_+|ATP-binding-protein
MTEVIRLDQVSLQRRTQEEFSYDLKRTIFSILEGKYRQPAKKLVLDDIDLVINSGAKLGIIGANGAGKSTLLKVICGILEPTKGQVRVRGQIASLIELGAGFDPDLPVKDNIILYGVMLGFSRQEMKEKTKDILDFAELEEYMGAPVKSLSSGMVARLGFAIATEVHPDILILDEVLSVGDESFKNKCKRRLKKFWNSNATILVVSHDLTLIQESCNQAIWLNKGQLQCQGASEDVIKFYLDSVHQNEVNF
>CP020664.1|AVQ71223.1|1537292_1538111_+|ABC-transporter-permease
MTIIPMTDLQAKTRWSTARRYYELLSVLVERNLKGRYRGSFLGVYWSLLNPLIMTALYTAIFGTVFASYFDNSLVNYVLAAFTGLVVINFFNASTNQALPSIVSNGSILNKIRLPVSIFPLSMVVANIFQFAISIFPLLAIVTLWKSQSLINVIALIFPVIGLSLVCTGVGFFVSTLYVFFRDLPYFYEIVCFVAWISSPIFYPPEIIPPSVQPFLLLNPLLPVIESIRQLSLSPGLPDFGLIFQSLLGGIIILGIGWTCFRLWRHLFMDLL
>CP020664.1|AVQ71222.1|1535974_1536850_+|ABC-transporter-ATP-binding-protein
MTAAIALDRVSKIYNNLPVVNELSFAIEKGEIFGLLGPNGAGKSTTIRMIITLTEASQGEIEVAGYNVKKYRDQVKRNIGVVLQQISVDGELTVWENLEFHGRMHHIPNPQRQELIDRYLDYVSLSDRKSALAKTLSGGMKRRLQIARALLHEPKILFLDEPTVGLDPQNRRRLWEVIRDLNQQGMTILLTTHYMEEVEFLCQDNAAGKPGRIGIMDGGKLIELGTLADFRAKYGEGLVIKQVGDKIDYKFFPTVADANSYLDTLSDKTGVMCRPSNLEDIFVELTGHQLD
>CP020664.1|AVQ71221.1|1535309_1535810_-|L,D-transpeptidase
MGVFLPILCLCLGIGEFFLNPPISLGNSPPATTVIRTETRLLLNLKKRRVFVYQGQKIIASYPVAIGRPGWETPTGQFRVIQMVREPVWEHPFTGQLVPSGKNNPLGARWIGFWTDGANFIGFHGTPQENLIGRAVSHGCVRMRDRDIKALFEKVQIGTSVIVVAQ
>CP020664.1|AVQ71220.1|1534929_1535184_-|hypothetical-protein
MNIIELIGIVAGILTTVSFLPQVIKTWRYRSAKDLSLTMFICFCLGVFLWLIYGLYMSSKPIIIANFVTFILAGTILYFKIKYD
>CP020664.1|AVQ71219.1|1533522_1534776_-|hypothetical-protein
MSNRIEWINALSTRPSLEAAVTEVVEKVQDKLVGSADLAIIFISSAYASDYPRLVPLILDKLPVPVLIGCGGAGIVGMGEREKAREIEASPALSLTVAHLPDVEVQPFYIEAAEMPDLDSSPSSWTELLGVEAAKNPQFILLADPFSSRINDLLEGLDFAYPGSAKIGGLVSGGMIERSGGLFYHDQQKPRNSYLYRQGTVGIALSGNIIVETIVAQGCRPIGPIYQVSEGERNIIISMTGKGADGTPQPPLNLLRDLIASLSEKDRELAQHSLFIGIARDEFKMQLRAGDFLIRNVLGVDPRQGAIAIGDRVRPGQRVQFHLRDADTSALDLELLLQAFPREKTDSSEVLGALIFSCLGRGENLYEKPDFDSGLFQRYFANVPLAGFFCNGEIGPVAGRTFLHGYTSAFALFRQGI
>CP020664.1|AVQ71218.1|1532770_1533484_-|hypothetical-protein
MIKAISFSESEIIYPDSDGKPMADNTKQFRWIVTIKENLECLFADNDHVFIAGDLLWYPVEGDNKTCQAPDAMVVFGRPKGDRGSYKQWLEDEIAPQVVFEILSPGNTKAEMRRKWQFYQRFGVEEYYLYDPDANDLQGWWRRGDQLEMIAAIDNWQSPLLQIRFQLESPQLAIFYPDGSRFLTTLEIKQKAELAEQRARTAEQQAQQERQRAREAEAKLARIEAQLRAIGINLEES
>CP020664.1|AVQ71217.1|1531994_1532774_+|hypothetical-protein
MNWQEIAGNWVFLPRRPRGIIHFLGGAFVAAAPNITYRWLLESLGNSGYAIVATPFVNTLDHKSIARTVLNRFDNIIERLRWNHSLPQGYLPIYGLGHSMGCKLHLLIGSLYEVEREGNILISFNNYPIRRAIPFIEPLQIDTTFNLEFTPSPEETNELIFQDYAIRRNLLIRFQDDTIDQSLVLNPLLKKRFNDLIALRTLPGNHLTPLSQDVSWQTGEVFTPLDAIGQWLKQGLARDNSRLKDEILHWLNPVLPTSR
>CP020664.1|AVQ74255.1|1531283_1531832_+|response-regulator
MSNHKILVIDDSKVIRMHVRDMLPEGNFEFLEAKDGLDGYHLIRTENPNLIILDFLLPKMSGWEVFQQIQTEDNLKSIPLVLMSGRKEEVVEKIPEPFQHFAFIEKPFDQKQLLQAIKEAMAKAKQYSPKPTVSNPKLEELTGDYSTDIQTLQSQIAQMQTEMETIKKQMSQLVAFIKKKLA
>CP020664.1|AVQ71226.1|1540529_1540721_+|hypothetical-protein
MRYHFLVSPDEKIFTPTEERDFLPYTRHPTPYTLFPVRRQKARGKRQKSNFAKTENLLLWYIK
>CP020664.1|AVQ71227.1|1540866_1541907_+|fatty-acid-desaturase
MTATTDKLPGELITSIEPDFKLKDIIKSIPKEYFQKDPVKAWLGVIMNILAVIAGYAMLVYSPWYLLPLAWIFTGTALTGFFVIAHDCGHRSFSNRRWVNDLVGHIFLLPLIYPFHCWRFLHDRHHAKTNMVTIDNAWDPWELEAFNSANPLVRLFYRGIRGRFWWLGSIAHWAILHFNIEQFKENEREKARFSMIVVLVFGAIFFPTLIFYTGVWGLVKFWVVPWFVYHFWMSTFTLVHHTDPDIQFFHPEDWNQALAQLEGTVHCSYPRWVEILCHDINVHIPHHISTAIPSYNLRKVHASLQENWGSHLKETEFSWPLMKRIVDYCHIFDSETAYKTFKESRG
>CP020664.1|AVQ71228.1|1542345_1543932_-|serine/threonine-protein-kinase
MTYCLNPNCSQPKNDPTALICESCGSKLLLHDRYQTLGILAKGGFGTTFVSSDLSLPGKPLCVVKQLRPSTDDPNVFAMARELFDREAETLAKLGVHPQIPRLLDYFEDNQQFYLVQEYVKGHNLHQEVKKRGPFSEAGVKQFLSELLPILQYVHERKVIHRDIKPANLIRRQTDRKLVLIDFGAVKNQVNTVIANADSQTALTNFAVGTQGFAPPEQMAMRPVYASDIYAVGVTCLYLLTGKSPKAIEVDVNTGELLWEKLVQVSPQFAKVLKRMLEVSVRHRYKSAQEVMDALDMTAYADSLAQSLIAAPVGTPLKPPEDSSPMGNFSVSAPLNSKFRPKNKNREASPNNMLDGQMALQIINTNVLSRGQARSSTDITLLKKKRRLDEKAILDAYNNGRRNFAQEELPNLNLAKAKLLGVNFCQSKLTGANLQGADLSKADLGRANLSQAILKSTNLNNAYLGYADLEGADLRGANLIGANLRYAHLKNANLCGANLSDAQVTPEQIALAKTNWLTVMPNGKRSSW
>CP020664.1|AVQ71229.1|1544392_1545883_-|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase
MKLQELLTTIPLVSPISSPIASITEITGISTNSHACQPGDLFIGLPGTRVDGGEFWRSALESGAVAALISPAAAAKFPPPEDACVIVVADLVTATAAIAAKFYHYPALTLKLIGVTGTNGKTTTTHLIEYFLSQAGIATALFGTLYTRWQGFQETANHTTPFANELQASLAKAVSAGNEIAVMEVSSHALAQGRVQGCTFPVTVFTNLTRDHLDYHLDMEDYFAAKAKLFSPDYLQGKAIINLDDEYGQRLAASLSPQQVLTYSVSDASADFYTKDLHYQPTGVEGVMVTPQGEIAFASPLVGQYNLANLLAAVAAVLECGVDLETVIAQIPQFSGVPGRMERVSIAPDQDISVIVDYAHTPDSLENVLKASRPFISGRMICVFGCGGDRDRTKRPLMGKIAAELADLAIVTSDNPRTESPERILEDIIAGIPPEITVQVISDRALAIDTAIQAAQPGDGVIIAGKGHEDYQILGTEKIHFDDREQARAALMKVKR
>CP020664.1|AVQ71230.1|1546382_1546577_+|hypothetical-protein
MNWGEGSGKWGDGEVGKWGSGEAVPSPYHPKTLSPYHPKTLSPYHPKTLSPYHPISCLLISAIS
>CP020664.1|AVQ71231.1|1546642_1547389_+|hypothetical-protein
MQFVDFLALIHPILAIVVVFPIIGLVVNFAWQTRQRRLETNAGNKSKIPPMVGPEHLRLGRWLTGTVVGVNLLALAYSVVYGFNGFVDKQKDGKLDSFQVIFVILMFFVTIASLVCLYRARQALWRGIFATLTGIGLIIIGSQDGVWRLSDQWYWSHYYIGMAASLLMIFSLAIVEDIYKDRSHRWRIAHTILNCIALALFLGQAMTGSRDLLEIPLSWQKPAIYRCDFTNKTCPEPKSSTPPINPIS
>CP020664.1|AVQ71232.1|1547429_1548848_-|hypothetical-protein
MNNRLCLHLMANREKGFALPLAVLIGLILMVTGMTMIMRAQGDQSKVIAQKVRADALTSSETGVARVQDLLNSVRVMATVDSNCTSGGDCWQNAEVVANPSTNLQRHLKKLVDAASSCSNPNDADTLTAKINELRGLSANTWFELGNNRYYRVVGYDYSTGPGKGVLTLEGRSRISTATDLTNTGPDIDSDDNAASRNRVVVTIPILDAPTRAFNRSTVPALWISEGTADDGASRFQGDVVEEVVSPECEAEQDKIQQPTPALNPPYTAQPQFVGVFFPNLPPIPTGLRDEQKNLALTSSETFPRTGDTASPSGVYEYIVNNINLSSGQITITPGQRVVFYVRGNINGAIGHDCGSVTGCKPGNLQIYADNGLGSAAPQICLRGDQTLQAFIFAPDYSLGKTGTGTFIGAAWGKNWGEITDCPSSIGAVAVTQGVEWTDLIQDLKPQFPQLDKIANWCEEPIDTAPDESECD
>CP020664.1|AVQ71233.1|1549220_1549475_-|hypothetical-protein
MKVFWKNMNGNLCVPLFIKRVRHLKSRPPWPEAVRMIASLGGFLGRKGDGEPGVKTIWLGLRRLHDISQTWKLSHQISPPIEPP
>CP020664.1|AVQ71234.1|1549623_1549884_-|transposase
MERQPYPSDLTDDEWEILKPLIPEHQGVGRPRTVNIREILNAIFYWVDNGIKWRAMPHDLPPWSTVYDYYQTSCKSLKSILVQQHF
>CP020664.1|AVQ71235.1|1550021_1550255_+|hypothetical-protein
MIIQKIIDELHEIPEDHLTQIYEIVRSFRLELERERSHNPDDTPDEEIVANLKQGMQEALAGNTIPLDRMWEDIDVD

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Crispr_ID: CP020664_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020664_8

1792501-1792596

Orphan

Consensus_repeat	Method
ATAAAATTTTCCCAAGCTCTCAGAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020664_8

>merge|CP020664|8|1792501-1792596|CRISPRCasFinder
ATAAAATTTTCCCAAGCTCTCAGACTGGGTTTCCCCCCGTATCTCTTACCTAAGACAGAGGCTGTCAAAGGATAAAATTTTCCCAAGCTCTCAGAC

>CP020664|8|8|1792501-1792596|CRISPRCasFinder
ATAAAATTTTCCCAAGCTCTCAGAC	TGGGTTTCCCCCCGTATCTCTTACCTAAGACAGAGGCTGTCAAAGG
ATAAAATTTTCCCAAGCTCTCAGAC

Protein	Signature genes	Signature genes Name	Protein_function
CP020664.1\|AVQ71419.1\|1789846_1790578_-\|galactosyl-1-phosphate-transferase	unknown	unknown	gnl\|CDD\|376775
CP020664.1\|AVQ71414.1\|1779583_1780693_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377008
CP020664.1\|AVQ71423.1\|1794430_1795678_+\|site-2-protease-family-protein	unknown	unknown	gnl\|CDD\|100085
CP020664.1\|AVQ71422.1\|1793581_1794208_+\|FraH-protein	unknown	unknown	gnl\|CDD\|224630
CP020664.1\|AVQ71416.1\|1782190_1782613_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71415.1\|1780968_1782180_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224113
CP020664.1\|AVQ71418.1\|1786627_1789480_+\|DNA-helicase-UvrD	unknown	unknown	gnl\|CDD\|182930
CP020664.1\|AVQ71421.1\|1792654_1793377_+\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|273494
CP020664.1\|AVQ74268.1\|1785784_1786357_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|99749
CP020664.1\|AVQ71426.1\|1798388_1798778_+\|30S-ribosomal-protein-S6	unknown	unknown	gnl\|CDD\|275387
CP020664.1\|AVQ71427.1\|1798784_1799462_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226983
CP020664.1\|AVQ71424.1\|1795596_1796361_-\|serine/threonine-protein-phosphatase	unknown	unknown	gnl\|CDD\|277316
CP020664.1\|AVQ71429.1\|1800537_1801239_+\|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	gnl\|CDD\|275017
CP020664.1\|AVQ71412.1\|1778545_1778962_-\|reactive-intermediate/imine-deaminase	unknown	unknown	gnl\|CDD\|129116
CP020664.1\|AVQ71425.1\|1796738_1797464_+\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
CP020664.1\|AVQ71413.1\|1779087_1779594_-\|endoribonuclease	unknown	unknown	unknown
CP020664.1\|AVQ74269.1\|1797460_1798243_-\|5-oxo-1,2,5-tricarboxylic-3-penten-acid-decarboxylase	unknown	unknown	gnl\|CDD\|223257
CP020664.1\|AVQ71417.1\|1782716_1785575_-\|isoleucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235588
CP020664.1\|AVQ71428.1\|1799674_1800262_-\|DUF3782-domain-containing-protein	unknown	unknown	unknown
CP020664.1\|AVQ71420.1\|1791283_1792081_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236545

Protein	Function_ID	Function_description	E-value
CP020664.1\|AVQ71419.1\|1789846_1790578_-\|galactosyl-1-phosphate-transferase	gnl\|CDD\|376775	pfam02397, Bac_transf, Bacterial sugar transferase. This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.	8.46809e-94
CP020664.1\|AVQ71414.1\|1779583_1780693_-\|hypothetical-protein	gnl\|CDD\|377008	pfam03235, DUF262, Protein of unknown function DUF262.	2.12281e-22
CP020664.1\|AVQ71418.1\|1786627_1789480_+\|DNA-helicase-UvrD	gnl\|CDD\|182930	PRK11054, helD, DNA helicase IV; Provisional.	6.66138e-31
CP020664.1\|AVQ71422.1\|1793581_1794208_+\|FraH-protein	gnl\|CDD\|224630	COG1716, COG1716, FOG: FHA domain [Signal transduction mechanisms].	3.99027e-19
CP020664.1\|AVQ71427.1\|1798784_1799462_-\|hypothetical-protein	gnl\|CDD\|226983	COG4636, Uma2, Endonuclease, Uma2 family (restriction endonuclease fold) [General function prediction only].	3.05871e-13
CP020664.1\|AVQ71415.1\|1780968_1782180_-\|hypothetical-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	8.24566e-11
CP020664.1\|AVQ71423.1\|1794430_1795678_+\|site-2-protease-family-protein	gnl\|CDD\|100085	cd06164, S2P-M50_SpoIVFB_CBS, SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. In this subgroup, SpoIVFB (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain. SpoIVFB is one of 4 proteins involved in endospore formation; the others are SpoIVFA (sporulation protein, stage IV cell wall formation, F locus, promoter-proximal A), BofA (bypass-of-forespore A), and SpoIVB (sporulation protein, stage IV cell wall formation, B locus). SpoIVFB is negatively regulated by SpoIVFA and BofA and activated by SpoIVB. It is thought that SpoIVFB, SpoIVFA, and BofA are located in the mother-cell membrane that surrounds the forespore and that SpoIVB is secreted from the forespore into the space between the two where it activates SpoIVFB. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown.	1.10534e-76
CP020664.1\|AVQ71421.1\|1792654_1793377_+\|6-phosphogluconolactonase	gnl\|CDD\|273494	TIGR01198, 6-phosphogluconolactonase_6PGL., 6-phosphogluconolactonase. This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway].	1.66485e-96
CP020664.1\|AVQ74268.1\|1785784_1786357_+\|hypothetical-protein	gnl\|CDD\|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	2.21051e-42
CP020664.1\|AVQ71426.1\|1798388_1798778_+\|30S-ribosomal-protein-S6	gnl\|CDD\|275387	cd15487, bS6_chloro_cyano, 30S ribosomal protein S6 of chloroplasts and cyanobacteria. bS6 is one of the components of the small subunit of the prokaryotic ribosome, a ribonucleoprotein organelle that decodes the genetic information in messenger RNA and forms peptide bonds to synthesize the corresponding polypeptides. Mitochondrial and chloroplastic ribosomes are similar to bacterial ribosomes. Ribosomes consist of a large and a small subunit, which assemble during the initiation stage of protein synthesis. Prokaryotic ribosomes consist of three molecules of RNA and more than 50 proteins. The small subunits of bacterial and eukaryotic ribosomes have the same overall shapes (with structural elements described as head, body, platform, beak and shoulder). The bacterial ribosomal protein S6 is important for the assembly of the central domain of the small subunit via heterodimerization with ribosomal protein S18.	5.10865e-52
CP020664.1\|AVQ71424.1\|1795596_1796361_-\|serine/threonine-protein-phosphatase	gnl\|CDD\|277316	cd00144, MPP_PPP_family, phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain. The PPP (phosphoprotein phosphatase) family is one of two known protein phosphatase families specific for serine and threonine. This family includes: PP1, PP2A, PP2B (calcineurin), PP4, PP5, PP6, PP7, Bsu1, RdgC, PrpE, PrpA/PrpB, and ApA4 hydrolase. The PPP catalytic domain is defined by three conserved motifs (-GDXHG-, -GDXVDRG- and -GNHE-). The PPP enzyme family is ancient with members found in all eukaryotes, and in most bacterial and archeal genomes. Dephosphorylation of phosphoserines and phosphothreonines on target proteins plays a central role in the regulation of many cellular processes. PPPs belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	8.56172e-34
CP020664.1\|AVQ71429.1\|1800537_1801239_+\|PEP-CTERM-sorting-domain-containing-protein	gnl\|CDD\|275017	TIGR04155, hypothetical_protein, PEP-CTERM protein sorting domain, cyanobacterial subclass. This domain model describes a subclass with family TIGR02595 of PEP-CTERM protein sorting signals associated with bacterial exosortases. This subclass is restricted to Cyanobacteria, including the genera Cyanothece, Nostoc, Trichodesmium, Lyngbya, Arthospira, etc. This PEP-CTERM subclass features strongly conserved residues within the transmembrane region, including a Gx4GxG motif. Model TIGR03763 describes a corresponding cyanobacterial form of exosortase found in most species with this domain.	0.0017366
CP020664.1\|AVQ71412.1\|1778545_1778962_-\|reactive-intermediate/imine-deaminase	gnl\|CDD\|129116	TIGR00004, RutC_family_protein, reactive intermediate/imine deaminase. This protein was described initially as an inhibitor of protein synthesis intiation, then as an endoribonuclease active on single-stranded mRNA, endoribonuclease L-PSP. Members of this family, conserved in all domains of life and often with several members per bacterial genome, appear to catalyze a reaction that minimizes toxic by-products from reactions catalyzed by pyridoxal phosphate-dependent enzymes. [Cellular processes, Other].	9.69509e-58
CP020664.1\|AVQ71425.1\|1796738_1797464_+\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	4.25283e-134
CP020664.1\|AVQ74269.1\|1797460_1798243_-\|5-oxo-1,2,5-tricarboxylic-3-penten-acid-decarboxylase	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.42913e-101
CP020664.1\|AVQ71417.1\|1782716_1785575_-\|isoleucine--tRNA-ligase	gnl\|CDD\|235588	PRK05743, ileS, isoleucyl-tRNA synthetase; Reviewed.	0
CP020664.1\|AVQ71420.1\|1791283_1792081_-\|hypothetical-protein	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	0.000224705

>CP020664.1|AVQ71420.1|1791283_1792081_-|hypothetical-protein
MNSFTSLSLKLTGLVFIISFLLDGFILPLPYQFSQSQWQVGFVTTFVDRGIVPLLGIILVLIAYWIEANNRDRDVIPRKSRFELRWPIFILSTLLGLVFLLMIPVHINNINQIKNNALTQIEQGVDQGEGQIQAFLAQLNTLSQNPQLLEQQISQRNQVIETGRFQGQTISTEQLQTLRQQREQLTNLRDLSKKPKEFKQRLDEIKNQLQTQLQDRRKQAESQANLEALKQWLRIGIQSMLLSICYSLIGWLGIRELGSMKKRTA
>CP020664.1|AVQ71419.1|1789846_1790578_-|galactosyl-1-phosphate-transferase
MTANSQLISVKALQALMKRGFKPSVSGRRHQKSWLIALDGDTSKRLFDIVFSLSVLIFFSPLYLILALLIAISSPGPVFYMQKRVGQNFQPFNCIKFRTMVMDADKVLERLMEDSPQLRAEFEDNFKLKDDPRITWIGKFLRLTSLDEFPQFWNVLRGDMSVVGPRPLVPEELQKYGNRIDKVLTIRPGLTGLWQVSGRNDIPYPMRVQMDVYYVNSRNWLTDIWVVFKTIGVVVFPKNNGAY
>CP020664.1|AVQ71418.1|1786627_1789480_+|DNA-helicase-UvrD
MDKSNLNKQLVINNIQEFAELVGNYDQAWKLLVGKKVSRIRAEVKYKGKKTGIKGTKNYKYGQIINIKYEDDTVSVHIKYQRNFFAEYKIEKIINQFSDIFPFITVQEIFQKVPEIKNKILEEIYQTLEYDFLNVNKLYQERLYKYLTKEEFGQEKYRFVQSWLEKNLGRKPDLEQSVAIGEVNNNIQVLARAGSGKTSTLVNKALFLQKHCGILPREILILAFNRKAAEEIRERIEHNSANNIPYVMTFHALAYGLVHPEEELIFDQSGGEQRKSKALQSVIDDHLKSPQYFSKIRDLMMAKFRGDWENLVRGGHLLNREEMLSYRRSLPREGLDGRYYKSFGEKAIANFLFEHNLFYSYERNYDWNGINYRPDFTIFTGKNQGIIIEYFGLQGDPDYDEMSARKRQFWQNAQNQARWQFLEFNPGDIKASQEQFGNLLKHKLESFGLLCNKLSEDEIWAKVKRRSIDHFTKAMVQFVQRCRQQFLTTEELENKIFNHNCLEEFESQFLELGQVFYRAYLERLKATGEEDFDGLMQTASKLITSGQTIFRRKSSGGDLRLLKYILIDEYQDFSELFYRLITAIRQQNSQACFFCVGDDWQAINGFAGSDLNYYQNFANYFPNSLKLNISTNYRSASAIVTTGNNLMNGLGKPAQPHKKESGFVKLVDLQDFEPTPREIEDHNGDHITPALLRLIKKIIIENNQEVVLLNRKNNLHWFVNYQNKLEDFLNAIRGYLPENLRDHLTISTSHKYKGLEKQVVIILDAVNRSYPLIHPDWVFTRIFGSHPEGIVAEERRLFYVAITRAIEQLYIITESPNYSPFLAHLNLNKINWQEYPIPGDNSKYITIEIGNQKGKGSHPTIQIRDLLKAQGYKWNSHQHRQIWYRHDLRASFTTVDDFFHQSSWYAIADGVEVCFYDDFRNLLCVCHVNNGQHDYLKAPNIELYSQDLEP
>CP020664.1|AVQ74268.1|1785784_1786357_+|hypothetical-protein
MVTNPNFFYVSPEVYLEGERVSPIKHEYRKGRIYAMVGAKKPHIVLNTNLATLLSIHLDDSPCLVLTSDIKVRLEEANCYYYPDIAVVCDEREINNTDDFILYPVLIIEVLSKSTESFDRGDKFSDYQTCPTLKEYILIHQNQMKIECHRREDSGVWQEQIYEAGDEVEFTSVGFRGSIASIYRKVPGLV
>CP020664.1|AVQ71417.1|1782716_1785575_-|isoleucine--tRNA-ligase
MSNAKSYKDTVNLPQTDFDMRANASKREPEIQKFWQDEQIYEKLAQNNPKELFILHDGPPYANGSLHIGHALNKILKDIINKYKLLQGYKVRYVPGWDCHGLPIELKVLQSLKSSEKEGLTPLKLRQKAHDFALQTQKEQCEGFKRYGVWGDWENPYLTLQPEYEAAQIAVFGKMALKGYIYRGLKPVHWSPSSQTALAEAELEYPEGHTSRSVYVAFPITSVSTPVLTPFLPNLSVAIWTTTPWTLPGNLAVALNPELNYSVVETSESNYLIVATDLVEKLADTFNRTLTIKATVKGLELEHTKYRHPLFDRESAILIGGDYVTTDSGTGLVHTAPGHGQEDYIVGQRYGLPILSPVDDKGNFTAEAGQFAGLNVLKDANEAIILALTEKGALLKEEAYQHKYPYDWRTKKPTIFRATEQWFASVEGFRELALEAIDSVRWIPATGKNRITSMVSERSDWCISRQRSWGVPIPVFYDEETNEPLLTEETINHVQAIFAVKGSNAWWELSVEELLPPSYRDNGRSYRKGMDTMDVWFDSGSSWNAVANARPELSYPADMYLEGSDQHRGWFQSSLLTSVAANGIAPYKTVLTHGFVLDEQGRKMSKSLGNVIDPNVIINGGKDQKKEPAYGVDVIRLWVSSVDYTNDVNIGQNILKQLVDIRNKIRNTARFLLGSLNDFDPVKDAVAYEELPEIDRYMLHRISEVFTEVTAAFESFQFFRFFQTVQNFCVVDLSNFYIDIAKDRLYISDPNSFRRRSCQTVYAIALENLAKAIAPVLSHLAEDIWQFLPYKTPYLSVFESGWLNIDPAWNNRQLADKWAKFRQLRTEVNKVMETARNDKAIGASLEAKVLLYVPDETLQQELELFNNCDSLTGNKVDELRYLFLSSQVELVSDISAIQTAEYKGESDFVSVGIVKADGEKCDRCWNYSTQVGKFADDPTICERCNAALKGEF
>CP020664.1|AVQ71416.1|1782190_1782613_-|hypothetical-protein
MEDYQSAFLQRHQDTEILCKSNRKIAAMHFGGITIECLLKSMILASVSNKEWKTKSNNPGHTITNPGHSLTAALKSNNRLYSRVQNYPDVIKWINIVENPSQNFIDMRYSSSEPNDDKYKEWLSAYTGLKRWLQKQATQL
>CP020664.1|AVQ71415.1|1780968_1782180_-|hypothetical-protein
MSETWLRSLKQKLTDIYVQKEAQEWVDLNVSTAGLLNITIVSDKFENLSTTQRREAVKNDIEQQHKSLGFISLYTIQEAASLDLKAPQLLDEKSIHTWQDLALWSANPQNQSPSSPELCLPRTVTFYSFKGGVGRTTALIHVAWILAMRGRKVVAVDLDLEAPGLSTAFPLNPSPKYGIVDYFYEKSYLPKGVTAKINITEIFGEVNIPDATGRLFIVPAGDLSLDYITKVDDLRATTILDNGETLWSNFSREIQNQLKPDLILVDSCTGINEWGALSLLQAANEAIIFLFPNEQNQKGIELLLQSLTSFGRLSLNFVFSPVPDLSDTGITKVTHAWQILQKHIDKNIDIDETTDHDLDIDSEDYLIIPYIPSIALADRYPVTGLLDYYTPIANLIDEDTNFQ
>CP020664.1|AVQ71414.1|1779583_1780693_-|hypothetical-protein
MVNYLSQEEKLLAAEEEKYLEEEDDVDFPPVDIIAYNEQRSCSDLVRMYQKKQLVIDPYFQRDVVWTDPQQTRFIDSLMKQLPIPSMCISLDYKTDKRYIIDGLQRITTIVKFLTTEDWKLSKLPDVDSSISGKTVEEIKTQHEELYERVENMTIPITMIRYDSSKKAHNNYIFNIFHRLNTGGVKLNNQEIRNCIYNGEFNTFLKECAQYENWLLLMDRKHQKASRFEDEELVLRFFAFYDGYHNYKGKLTRFLNDYMYKHRLAHEDFIQSKDRLFKQTVDLIYDKISTGEPIKTSKVITEGILLGVAKNLDTLVNLSNDELQDKYSRLIKSEPFLTKNLASGIYQKDKALERINTSIKIFSSTGNDY
>CP020664.1|AVQ71413.1|1779087_1779594_-|endoribonuclease
MITKSYLFKTLNRLDQLYNDPTADNQKTSSYSKLALIELCGWIEETMDDIVLRCAKRCLKSPANQKFIKDEIIKPNSNFQYEAFRKMLIMVIGLATLEKIEKKLEKTGKISALKGDLVNLKRSRNRAAHTHTKGTLRTYDAPSKTQHDFDRIYALLTELDAELQRHKC
>CP020664.1|AVQ71412.1|1778545_1778962_-|reactive-intermediate/imine-deaminase
MSSFLTILPMNNQVIRTDKAPAPVGPYNQAIAATGPFLFVAGQIPLDPVTGEIVSGEISAQTEQVMANLEGILTAAGANWSNVVKTTVFLSDLANFGAMNQVYARYFPPETAPARACVEVARLPKDVLVEIECIAALA
>CP020664.1|AVQ71421.1|1792654_1793377_+|6-phosphogluconolactonase
MQKLVEILADKQALIAKSLALVLEKITTSLDQQDHFTIALSGGSTPKPLYEALSSQPLDWSRIHVFWGDERYVSPDHPDSNQRMARLAWLDRIPIPAANIHPMPTDDPDPHRAAQKYDDHLRQWFGVNSPDFPVFDLILLGMGDDGHTASLFPHTAALTVSDRCITVGEKDGNPRLTFTVPLINQARCVIFIAAGESKRPALHEIFSAYGDSFSYPSRLIHPPAGELYWLLDAAAGSSFV
>CP020664.1|AVQ71422.1|1793581_1794208_+|FraH-protein
MIVCPNCEHTNPDEATQCEACYTPLPRMSFCPSCGATIQTDATFCGQCGYNLQPNSVPMVAAEAEPEPEPVPPVPTATGASIAPPPVAPPPVPAATRLQMEMASLQHLQTDSKIELPLHLSVIHIGKPNARIPPDIDVSGFPDSDIVSRVHADIRVEGGIYYLEDSGSANGTYVNHTPLPPGNRHRLRAGDRISLGKGDKMTFIFQMS
>CP020664.1|AVQ71423.1|1794430_1795678_+|site-2-protease-family-protein
MGTNWRIGSLLGIPLYIDSSWFLILAFVTLINATDAEIQSQAGQSSILAWLLGLIIALLLFISVLLHELGHSFMARCQGIKVNSITLFLFGGMASIDRESRTPPEALQVAIAGPLVSFLLFCLLSLASHLPYLNANLTYICGHLAIINLFLALFNLIPGLPLDGGQIFKAIVWQATGDRWKGLHWAAISGQLIGWLGIILGIFLVLLTAAVEGAWLGLMGWFILRNARAYDNLTNLQESLLNFTAGEVMSRHLRVLNAHQTLEEFAQEYVLDRAAANTAYFAASEGRYRGLIRVEDLQAIERSFWSEKQLLDLAHPLAEIATVEEKTPLVTVVQKLETIPDRMITVLTPASAVAGVIDRGDILKAIAIKYQIPLEETDIERAREGVYPSYLPLNVIAAALDKSEPPKIGEPSLMS
>CP020664.1|AVQ71424.1|1795596_1796361_-|serine/threonine-protein-phosphatase
MRTLAIGDIHGCSKALDHLLEIVNPKPQDTLITLGDYVNKGRDSKGVIDRLISLHKQGNLIPLKGNHEIIMLQARNNPLKQRLWLEKGGKATLKSYSEGHLIKIPESHWDFLGKVCINSYETANHLFVHAGLDPNLPLARQPEYKLFWEKFQYPAAHSSGKTMICGHTSQKSGKPVNLGHAICIDTWAYGQGWLSCLDVETGKLWQVNQRGNFRISHIQDYYRPSSLGQDIKEGSPIFGGSLLSRAAAITFKGK
>CP020664.1|AVQ71425.1|1796738_1797464_+|triose-phosphate-isomerase
MPKVVIAGNWKMHKTQREALEFLQDFKSHLDETPDDREVVLCAPFTALAVLSKTLHGGRIRLGAQNVHWEKSGAYTGEISADMLTEIGVHYVVIGHSERRQYFGETDETVNLRVISAQKQGLIPIICVGESKAQRDAGETEKVIIKQIQAGLVNVDQKNLVIAYEPIWAIGTGETCESEEANRVIGLIRQQLDNPEVTIQYGGSVKPDNIDEIMAQSQINGALVGGASLDPAVFARIVNYR
>CP020664.1|AVQ74269.1|1797460_1798243_-|5-oxo-1,2,5-tricarboxylic-3-penten-acid-decarboxylase
MAQRYVRVKHRQGQIFYGLLQLNRSVAVFDAPPWQGGQLTKIELEPDSYQLLAPCFPSKIIAVGKNYRAHAAEMGTPVPEEPLLFLKPPTTIIADGETIFYPPQSERVDYEGELALIIGETAKNCTTAQARSKIWGYTIANDVTARDLQKKDSQWTRAKGFDSFCPLGPWIVRELSIGAQLTTFLNDGSEPKQSSYLSDMVFPPDVLVAYISQVMTLLPGDVILTGTPEGIGPMQVGDKVRVEIEGIGVLENSVMAAEIN
>CP020664.1|AVQ71426.1|1798388_1798778_+|30S-ribosomal-protein-S6
MSNNYETLYILRPDLGEEVVQQQVERYRTLISEHSATDIEVKVWGKKRLAYPIKKLNDGVYVQMNYQASGKQVAPMERAMRLSDEVIRYLTLKLDRVVAPPADLSPLTEIPPSPITEAVVEDDGISAED
>CP020664.1|AVQ71427.1|1798784_1799462_-|hypothetical-protein
MVQAPIEPQLFYPDSDGKPMADNTVQYRWIVRLVANLRYLFKGQTVFVAGDLLWYPQQVTVPPAPRQAPDAMVVFGRPPGERGSYKQWEEDHIAPQVVFEILSPSNSAREMLKKQSFYREYGVLEMFFYDPDSHDFWGLVRPNQQEDFFPVTALNFPWTSPILGIRFEMFEEGLEVFYPDGERFKDPETLFEERNQAQQERDQAQQERDRAFARLRELGIDPTQL
>CP020664.1|AVQ71428.1|1799674_1800262_-|DUF3782-domain-containing-protein
MATTSEDVWRLLAELATAQKETDKQLKETDLLLKEVSQQQKKTDKQLKELGQQIGGLGAKFGSFTEGLALPSMEKILRQRFGMEVVSPSVRVSKDGKHLEIDVLAYTNGELNTAYIVEVKSHAREESISQLKSILQRFRRFFPEHKDKKLYGILAAVHLSSELREKILQEGFYVARIHDQVFELDIPDNFQPRLY
>CP020664.1|AVQ71429.1|1800537_1801239_+|PEP-CTERM-sorting-domain-containing-protein
MDCRGGGKNSLSKLAIASSAIAFSTLAISPVQAAQLIIPNTTVLGTNVFSGPTFTVSQNFLPSDTLSVNVSGTVDIWAGTLAMNAAGIITQTTQPGFSVGQTIAAGSGATRPGQPSGSLLIGNSTLGFFPLFSANAANGLGSANPPTNLSLSGVPLSSIFTNVGFTGIANGTVLQFRINDINSSDNSGQFVISSPPPSTSTPEPSTILGLGVLGLGAFCQRKLSQGKKSKQDN

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Crispr_ID: CP020664_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020664_9

2096611-2096709

Orphan

Consensus_repeat	Method
AAGTTTGACAGCCTGTCTTTTGACAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020664_9

>merge|CP020664|9|2096611-2096709|CRISPRCasFinder
AAGTTTGACAGCCTGTCTTTTGACAAAAAAGTAAAAGTTTGCTTTTAACTGTCCCATTGATTAATTCTACACGAAGTTTGACAGCTTGTCTTTTGACAA

>CP020664|9|9|2096611-2096709|CRISPRCasFinder
AAGTTTGACAGCCTGTCTTTTGACAA	AAAAGTAAAAGTTTGCTTTTAACTGTCCCATTGATTAATTCTACACG
AAGTTTGACAGCTTGTCTTTTGACAA

Protein	Signature genes	Signature genes Name	Protein_function
CP020664.1\|AVQ71687.1\|2100345_2101047_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276809
CP020664.1\|AVQ71679.1\|2090205_2090409_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375932
CP020664.1\|AVQ71688.1\|2101003_2101252_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71682.1\|2096200_2096578_-\|plastocyanin	unknown	unknown	gnl\|CDD\|235060
CP020664.1\|AVQ71692.1\|2103236_2104973_+\|tail-length-tape-measure-protein	unknown	unknown	gnl\|CDD\|227708
CP020664.1\|AVQ71690.1\|2101504_2101687_+\|addiction-module-toxin,-HicA-family	unknown	unknown	gnl\|CDD\|377942
CP020664.1\|AVQ71674.1\|2086647_2086866_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378367
CP020664.1\|AVQ71680.1\|2090553_2090781_-\|prevent-host-death-protein	unknown	unknown	gnl\|CDD\|226603
CP020664.1\|AVQ71678.1\|2089407_2089740_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71684.1\|2097207_2098887_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371750
CP020664.1\|AVQ71691.1\|2102019_2103159_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276809
CP020664.1\|AVQ71675.1\|2086962_2087298_-\|XisI-protein	unknown	unknown	gnl\|CDD\|341357
CP020664.1\|AVQ71676.1\|2087385_2088882_-\|IS5/IS1182-family-transposase	unknown	unknown	gnl\|CDD\|290319
CP020664.1\|AVQ71686.1\|2099575_2099995_+\|putative-toxin-antitoxin-system-toxin-component,-PIN-family	unknown	unknown	gnl\|CDD\|224485
CP020664.1\|AVQ71681.1\|2094017_2095745_-\|succinate-dehydrogenase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|180319
CP020664.1\|AVQ71677.1\|2089154_2089400_-\|DUF4926-domain-containing-protein	unknown	unknown	gnl\|CDD\|379816
CP020664.1\|AVQ71683.1\|2096770_2097091_+\|cytochrome-c6	unknown	unknown	gnl\|CDD\|184253
CP020664.1\|AVQ71685.1\|2099309_2099579_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71689.1\|2101316_2101508_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71673.1\|2086224_2086539_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225291

Protein	Function_ID	Function_description	E-value
CP020664.1\|AVQ71679.1\|2090205_2090409_-\|hypothetical-protein	gnl\|CDD\|375932	pfam18506, RelB_N, RelB Antitoxin alpha helical domain. This is an alpha helix domain found in the N-terminal region of antitoxin RelB. RelE-RelB (RelBE) is a toxin-antitoxin (TA) protein complex. It is suggested that the toxic action of RelE is counteracted by antitoxin RelB, which wraps around RelE, blocks its active site and prevents sterically the binding to the ribosomal A-site.The long N-terminal alpha-helix of the tightly bound antitoxin RelB covers the presumed active site of the toxin RelE that is formed by a central beta-sheet.	1.228e-10
CP020664.1\|AVQ71682.1\|2096200_2096578_-\|plastocyanin	gnl\|CDD\|235060	PRK02710, PRK02710, plastocyanin; Provisional.	1.03814e-67
CP020664.1\|AVQ71692.1\|2103236_2104973_+\|tail-length-tape-measure-protein	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	2.2979e-21
CP020664.1\|AVQ71690.1\|2101504_2101687_+\|addiction-module-toxin,-HicA-family	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	1.50836e-08
CP020664.1\|AVQ71674.1\|2086647_2086866_-\|hypothetical-protein	gnl\|CDD\|378367	pfam10049, DUF2283, Protein of unknown function (DUF2283). Members of this family of hypothetical bacterial proteins have no known function.	2.82922e-16
CP020664.1\|AVQ71680.1\|2090553_2090781_-\|prevent-host-death-protein	gnl\|CDD\|226603	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	5.79924e-05
CP020664.1\|AVQ71684.1\|2097207_2098887_+\|hypothetical-protein	gnl\|CDD\|371750	pfam11832, DUF3352, Protein of unknown function (DUF3352). This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 538 to 575 amino acids in length.	9.438e-178
CP020664.1\|AVQ71691.1\|2102019_2103159_+\|hypothetical-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.36152e-24
CP020664.1\|AVQ71675.1\|2086962_2087298_-\|XisI-protein	gnl\|CDD\|341357	cd16382, XisI-like, XisI is FdxN element excision controlling factor protein. This family contains XisI proteins, also known as FdxN element excision controlling factors, and similar proteins. FdxN element is excised from the chromosome during heterocyst differentiation in cyanobacteria. This is accomplished by the large serine recombinase XisF (fdxN element site-specific recombinase). The xisH as well as the xisF and xisI genes are required. XisI may function as recombination directionality factor (RDF), and needs XisH which may function as an endonuclease.	3.51688e-54
CP020664.1\|AVQ71676.1\|2087385_2088882_-\|IS5/IS1182-family-transposase	gnl\|CDD\|290319	pfam13586, DDE_Tnp_1_2, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	2.0941e-34
CP020664.1\|AVQ71686.1\|2099575_2099995_+\|putative-toxin-antitoxin-system-toxin-component,-PIN-family	gnl\|CDD\|224485	COG1569, COG1569, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	5.8853e-24
CP020664.1\|AVQ71681.1\|2094017_2095745_-\|succinate-dehydrogenase-flavoprotein-subunit	gnl\|CDD\|180319	PRK05945, sdhA, succinate dehydrogenase/fumarate reductase flavoprotein subunit.	0
CP020664.1\|AVQ71677.1\|2089154_2089400_-\|DUF4926-domain-containing-protein	gnl\|CDD\|379816	pfam16277, DUF4926, Domain of unknown function (DUF4926). This family consists of uncharacterized proteins around 70 residues in length and is mainly found in various Caulobacter, Microcystis and Cyanothece species. The function of this family is unknown.	2.9023e-15
CP020664.1\|AVQ71683.1\|2096770_2097091_+\|cytochrome-c6	gnl\|CDD\|184253	PRK13697, PRK13697, cytochrome c6; Provisional.	2.05842e-46
CP020664.1\|AVQ71687.1\|2100345_2101047_+\|hypothetical-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.20692e-23
CP020664.1\|AVQ71673.1\|2086224_2086539_-\|hypothetical-protein	gnl\|CDD\|225291	COG2442, COG2442, Uncharacterized conserved protein [Function unknown].	1.15748e-26

>CP020664.1|AVQ71682.1|2096200_2096578_-|plastocyanin
MKKLGLLFATVALVLSSFFFNTAAASAETFTVKMGGDAGTLQFDPPALTIKAGDTVKWVNNKLSPHNIVFDSTKVPEAQAAKLSHKGLAFSAGESFESTFSEPGTYTYYCEPHRGAGMVGTITVE
>CP020664.1|AVQ71681.1|2094017_2095745_-|succinate-dehydrogenase-flavoprotein-subunit
MKEHDVVIVGGGLAGCRAALEIKRLNPTIDVAVVAKTHPIRSHSVAAQGGIAAALQNVDPKDNPKAHAYDTVKGSDFLADQDAVDILTQEAPEVIIELEHLGVLFSRLEDGRIAQRAFGGHSHNRACYAADKTGHAMLHELVSNLGRNQVKIYDEWYVLRLILEEGTAKGVVMYQIATGQLEILRAKAIMFGTGGYGRVYNTTSNDFACTGDGLALSAKAGIPLEDMEFVQFHPTGLYPVGVLISEAVRGEGAYLINSEGRRFMEDYAPSRMELAPRDITSRAITLEIRAGRGVNLDGSAGGPFVYLDLRHLGREKIMSRIPFCWEEAHRLVGVDAVEEPMPVRPTVHYCMGGIPVNTDGRVRLSADTLTEGFFSAGECSCVSVHGANRLGSNSLLECVVYGRRTGKSIAKYVEKRAFPVFNPDIYLQDAKEEITALLTKKGTIRIGQLRQQFQDCMTQHCGVFRTEATMREGIKQIGELKRQYEQIYLDDRGDCWNTELIEAWELQSLMVVGEIILTSALNRQESRGAHSREDFPQRDDQNFLQHTLAYYSPSGIDIDYMPVVIQDFTPVERKY
>CP020664.1|AVQ71680.1|2090553_2090781_-|prevent-host-death-protein
MIKLTLNEAQSQLPDLLKAASKGEQVIIQNHEGQDFQIISLAPTVKHPQYGSAKGIVKMLDNFDDPIEEFEEYMP
>CP020664.1|AVQ71679.1|2090205_2090409_-|hypothetical-protein
MNIKDYPFAQDLITDNQGQIQQVIINFEDYQQIIETYEDTGLYCAMIDVKDETPLTLEEALIELEKE
>CP020664.1|AVQ71678.1|2089407_2089740_-|hypothetical-protein
MKLPNADQANLGDKLERYCLNPEHSKGKHKALLFKQRLGITLANKEILENALKKAVMEGEAELYKIDQYGTHYDLKFNLCTDIGESLILSCWIVQITENFPRLTNVYPIN
>CP020664.1|AVQ71677.1|2089154_2089400_-|DUF4926-domain-containing-protein
MMNTIQEYDLVALTEDVTATHKTTHQPILLRRGQMGTVLMSFNQQAFLIDFTDQNGQTFAMETVDHSKLLRLISEPELVSV
>CP020664.1|AVQ71676.1|2087385_2088882_-|IS5/IS1182-family-transposase
MYRKSELPSTPPENFELPFEGKLSQDNRWVIMANLIPWSEFEAEYASLFSEEMGTPAKTFRTALGALIIKEKLGTSDRETVEQIKENPYLQYFLGFSSYSNEPRFEASMLVHFRERITLELINKVNRFMVKNSREIKEEENTEKKLESETQSQPENRGKLILDASCAPADISYPTDLNLLNQGRKQTEKIIDILYETLKGKLVQKPRTYRLLARKSYLEVAKKRKPTVKQRRKALKRQLQYLKRNLDHIEQLLAEGASLQSLKKRDYKLLLVVTEVYRQQLWMYQNNKQSIEDRIVSLTQPHIRPIVRGKAGKPVEFGAKFSASCIDGYIFLDRISWDNFNESGDLKAQIEAYYDYTGYYPESVHVDKIYRTRENRAWCKERGIRISGPPLGRPAKNVSKEQKKQATDDERIRNCIEGKFGQGKRRFSLGKVMAKLPHTSFSAIAITFLVMNLSNLLRQVFWAFLCLKWKNSTFSRSMIRISYNLKINQQLKLMLVAK
>CP020664.1|AVQ71675.1|2086962_2087298_-|XisI-protein
MDKLNHYRKIIHQILVPYSQIIYNNADIQNRLAFDPQNDQYLVISEGWQQNQRYHDCLIHLEIINDKIWVQCDNTEDGITKELLSAGIAKEDIVLGFHEPKIRQYTGFAVA
>CP020664.1|AVQ71674.1|2086647_2086866_-|hypothetical-protein
MKITYFQDTDTLYLEFNNNPIVETQEINENTLVDLDQQGNICAITLEHAKSLTDLNAFSLETIVAPQLASSL
>CP020664.1|AVQ71673.1|2086224_2086539_-|hypothetical-protein
MTTTLINHIEITPETCGGKPRIAGHRIKVQDVVIWHERLGMSPDEIVYHYPSITLADVYAALSYYHDHLEEIRQQITDDDTFAKEMQAKTPSLVQEKLKKMNGQ
>CP020664.1|AVQ71683.1|2096770_2097091_+|cytochrome-c6
MKRLLISLCLLLAVVTFGMARPALADGASIFSANCASCHMGGKNVVNAAKTLKKEDLVKYGKDSVEAIVTQVTKGMGAMPAFGGRLSAEDIEAVANYVLAQAEKGW
>CP020664.1|AVQ71684.1|2097207_2098887_+|hypothetical-protein
MKLRSFFYILGATVIILLGVATASFAWILADSPLSLLKGGVLREPAAAIFVPKQAPVMVSLLVNPERLESFGQLIATPANRRRSHQEIKDLEKSLLGKTGLNYQKEIKPWLGEEITLAVTSLDFDRDTDNGIQPGYLLAIQSKDGERAKEFLQASYSKQAVSGKFDLVFELYKGVNLIYQRPLTAGDNNRFLASAVVGDTVLFANNIKVLREALNNVQVPDLNLKNSPDYREALKNITEPRIAIVYGNLPPLSAWIANQPVPESPEAKQRLATAFTLKSGGIVAQTALIGVLGQDDQAPILSSPVGALSFIGENSLLVAASRDLNRFWTQVEEGLEADSPLQELITQVLNRFQSPLGLNLPEDVFSWVRGEYSLALVPSSKGMEPDSVFLGERVMGVEVDSAIEHLDELARSRGYNVVNLPLLDRTVTAWTKLTTAVPGGKAQLETLVTGVHTRVDNYEIIASSVEAMGLALSAQKNPILSSGKFRQAITALPAENDGYFYVDWRQLQPVIEAKFPIVRVLELSIKPLFNNLRSLTISSQGSENSVRRGTIFFNLGVKS
>CP020664.1|AVQ71685.1|2099309_2099579_+|hypothetical-protein
MTKELLIQINREGNLELPPEVQTRLNPGDKYMISLTEDSIILKKVHQDKVNLEQFFERLEAMEPDPNQPTLAEISQMIKEARQIRRANS
>CP020664.1|AVQ71686.1|2099575_2099995_+|putative-toxin-antitoxin-system-toxin-component,-PIN-family
MKVVVDVNVWISGLLWGGVPGKILKLAKNQRITIFASQKILADIEDTLERPKLQSRKQYCGYTTAYLMTIVQELIQPCVDRLLEVPQLRDADDAVILASAIVIQAEVIITGDLDLLTLHDFENIPIITPQEFLSRYFNE
>CP020664.1|AVQ71687.1|2100345_2101047_+|hypothetical-protein
MKSFALLTTVSLISLSTLATVRPVMALESRQPAETRIAQGNNQDAIGHYNRGVGYIQQEKYDLALAEFTKAININPRFAEAYLNRGLLYAVQGKPDLALSDFNQALNINPRDAIAYLNRGGLYRQQGKPDLALSDYNQALNINPRFAEAYRNRGNLYKEQGKPDLALSDYNQAININPRYAMAYGFRGLLYYSRQEREKAIRDLRQAAELYRQQGNAALYEKVMELLRELGAV
>CP020664.1|AVQ71688.1|2101003_2101252_+|hypothetical-protein
MKRLWNSYGNWARSSPFSWVESVGGVERINGLKKTSQFSGKGKPNSQHLNPSESAIANFVGCINECQAAISLPTLIIKLIVA
>CP020664.1|AVQ71689.1|2101316_2101508_+|hypothetical-protein
MRIPYTYWKESDGMFLGYLNEFPDHWTQGVDLEELIENLIDLYRTFTTEEIPGIKRVAEFEFA
>CP020664.1|AVQ71690.1|2101504_2101687_+|addiction-module-toxin,-HicA-family
MKRHDLIAQLEQAGCYLIRRGGKHDIYHNPDTGKTEPIPRHREINERLAKKIIKSLTGDR
>CP020664.1|AVQ71691.1|2102019_2103159_+|hypothetical-protein
MKSFALLTTVSLISLSTLATVRPVMALESRQPAETRIAQGNNQDAIGYFNRGIDYIQQEKYDLALAEFTKAIELDPNYTEAYNNRGFLYAGQGKPNLALSDYNQAININPRYAEAYLNRGLLYQQQGKPDLALSDYNQAININPRDADAYLNRGVLYAIQGKPDLALSDFNQAININPRDAQAYNNRGNLYGEQGKPDLALSDYNQAININPRDADAYLNRGVLYAIQGKPDLALSDFNQAININPRDAQAYNNRGNLYGEQGKPDLALSDFNQAININPRDAQAYNNRGNLYGEQGKPDLALSDYNQAININPRYAEAYVNRGVLYYSRQETEKAIRDFRQAAELFRQQGNAALYLNFPPYIYTTIAENPYPSMDAPP
>CP020664.1|AVQ71692.1|2103236_2104973_+|tail-length-tape-measure-protein
MYIEKVPNRNSPPAVLLRESYREGDQVKKRTLANLSKLPDDIIENLKLALKGATLSMNEGIPNHFEVIRSLPHGHVMAILETIKKLGLDKIINEKSSRIRNLVVAMIVARIINPKSKLATARGFNSETCSQSLGQLLDLEKGDEDELYNALDWLLEKQEKIEKHLAIKHLESGTLVLYDVTSTYLEGNGCELGKYGYNRDKKKGKTQIVFGLLCSAKGCPIAVEVFEGNTSDGATLSGQIEKVRKGWGIENVVWVSDRGILTNSKIKELVKPIEGLDYITGLTKPQIRKLAEVEVIQLGLFDQVNLVEFESEDYPEERLIACRNPLIAQKNQLQREALLEAVEKELDLIVQATQREKRALKGQDKIALRVGKILNQFKVNKYYNLEIKEEGFSYQRKRELIAQETALDGVYVLRTSLESTLMDAATTVKAYKSLSQVEEAFRCYKSIDLKVRPIYHYKGDRVKAHIFLCMLAYYVEWHLKQCLAPLLFEDEEIDDGSLNVIKANRSESAQSKERKKRNQENFPVHSFRTLLEDLGTICLNTVECTIREGSYRFSKITRPTQLQQKALDLLGVSLICTQ

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Crispr_ID: CP020664_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020664_11

2435313-2436166

TypeIII

Consensus_repeat	Method
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	PILER-CR
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	CRISPRCasFinder
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	CRT

11 spacers

cas10,cmr3gr5,cmr4gr7,cmr5gr11

The CRISPR arrays of CP020664_11

>merge|CP020664|11|2435313-2436166|PILER-CR,CRISPRCasFinder,CRT
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAACAAAAAACCTCCACTCGCCAGAATAAAATTCTGAGCAACCTTACCTATTAGGTCAAATAGGATTAGTTGGAAACATAGCGACTTTGTACGTTACCCCAATGATGGCTGCCTTACCTATTAGGTCAAATAGGATTAGTTGGAAACAGCAATAGCGCGCTTATGACACCTAGCGAATAAAACGCTCCTTACCTATTAGGTCAAATAGGATTAGTTGGAAACAGCTGGATAGCTGTTTGGATTTCGATGGCGGCACGGCCTTACCTATTAGGTCAAATAGGATTAGTTGGAAACTTGCTGGTTTGATGTCCACAGCCCGACCAAAAATATGCTCCTTACCTATTAGGTCAAATAGGATTAGTTGGAAACGAAGAAGCATCCCATGATAGGTGAACATGGATTACAACCTTACCTATTAGGTCAAATAGGATTAGTTGGAAACCCGATAATTTCGCCATTTTCAACTCTATCAGCTAAAACCTTACCTATTAGGTCAAATAGGATTAGTTGGAAACACCAAAGTGATTTGGTAGTAGTATGTGAAAAACCACCTTACCTATTAGGTCAAATAGGATTAGTTGGAAACAACATTTTACTAGCGAAGGCTCGCCTCGTAAGAAAAAAACAACCTTACCTATTAGGTCAAATAGGATTAGTTGGAAACCCATAGAAGTTTTCCTGCCAAATAGCGTCCAAATTGGACACCCCTTACCTATTAGGTCAAATAGGATTAGTTGGAAACGCGGCATCCTTTTTGTAACAATCTCCTTGGATAGACTCGAAGGACCTTACCTATTAGGTCAAATAGGATTAGTTGAAAGG

>CP020664|11|5|2435313-2436086|PILER-CR
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	AAAAAACCTCCACTCGCCAGAATAAAATTCTGAGCAA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	ATAGCGACTTTGTACGTTACCCCAATGATGGCTG
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	AGCAATAGCGCGCTTATGACACCTAGCGAATAAAACGCT
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	AGCTGGATAGCTGTTTGGATTTCGATGGCGGCACGG
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	TTGCTGGTTTGATGTCCACAGCCCGACCAAAAATATGCT
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	GAAGAAGCATCCCATGATAGGTGAACATGGATTACAA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	CCGATAATTTCGCCATTTTCAACTCTATCAGCTAAAA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	ACCAAAGTGATTTGGTAGTAGTATGTGAAAAACCA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	AACATTTTACTAGCGAAGGCTCGCCTCGTAAGAAAAAAACAA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	CCATAGAAGTTTTCCTGCCAAATAGCGTCCAAATTGGACACC
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC

>CP020664|11|11|2435313-2436166|CRISPRCasFinder
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	AAAAAACCTCCACTCGCCAGAATAAAATTCTGAGCAA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	ATAGCGACTTTGTACGTTACCCCAATGATGGCTG
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	AGCAATAGCGCGCTTATGACACCTAGCGAATAAAACGCT
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	AGCTGGATAGCTGTTTGGATTTCGATGGCGGCACGG
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	TTGCTGGTTTGATGTCCACAGCCCGACCAAAAATATGCT
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	GAAGAAGCATCCCATGATAGGTGAACATGGATTACAA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	CCGATAATTTCGCCATTTTCAACTCTATCAGCTAAAA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	ACCAAAGTGATTTGGTAGTAGTATGTGAAAAACCA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	AACATTTTACTAGCGAAGGCTCGCCTCGTAAGAAAAAAACAA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	CCATAGAAGTTTTCCTGCCAAATAGCGTCCAAATTGGACACC
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	GCGGCATCCTTTTTGTAACAATCTCCTTGGATAGACTCGAAGGA
CCTTACCTATTAGGTCAAATAGGATTAGTTGAAAGG

>CP020664|11|4|2435313-2436166|CRT
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	AAAAAACCTCCACTCGCCAGAATAAAATTCTGAGCAA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	ATAGCGACTTTGTACGTTACCCCAATGATGGCTG
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	AGCAATAGCGCGCTTATGACACCTAGCGAATAAAACGCT
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	AGCTGGATAGCTGTTTGGATTTCGATGGCGGCACGG
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	TTGCTGGTTTGATGTCCACAGCCCGACCAAAAATATGCT
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	GAAGAAGCATCCCATGATAGGTGAACATGGATTACAA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	CCGATAATTTCGCCATTTTCAACTCTATCAGCTAAAA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	ACCAAAGTGATTTGGTAGTAGTATGTGAAAAACCA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	AACATTTTACTAGCGAAGGCTCGCCTCGTAAGAAAAAAACAA
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	CCATAGAAGTTTTCCTGCCAAATAGCGTCCAAATTGGACACC
CCTTACCTATTAGGTCAAATAGGATTAGTTGGAAAC	GCGGCATCCTTTTTGTAACAATCTCCTTGGATAGACTCGAAGGA
CCTTACCTATTAGGTCAAATAGGATTAGTTGAAAGG

Protein	Signature genes	Signature genes Name	Protein_function
CP020664.1\|AVQ71947.1\|2432989_2434021_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380122
CP020664.1\|AVQ71946.1\|2431557_2432982_-\|CRISPR-associated-protein-Cas10	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|187810
CP020664.1\|AVQ71955.1\|2441616_2442951_-\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	unknown	unknown	gnl\|CDD\|235422
CP020664.1\|AVQ71958.1\|2444141_2445539_-\|trigger-factor	unknown	unknown	gnl\|CDD\|234956
CP020664.1\|AVQ71949.1\|2436585_2437869_+\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
CP020664.1\|AVQ71942.1\|2425551_2427180_-\|RAMP-superfamily-protein	unknown	unknown	gnl\|CDD\|213662
CP020664.1\|AVQ71954.1\|2441385_2441595_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71956.1\|2442962_2443664_-\|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
CP020664.1\|AVQ71940.1\|2422761_2424225_-\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|206646
CP020664.1\|AVQ71944.1\|2427612_2428440_-\|CRISPR-associated-protein-Csm4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl\|CDD\|224255
CP020664.1\|AVQ71939.1\|2422238_2422535_+\|plasmid-stabilization-protein	unknown	unknown	gnl\|CDD\|368240
CP020664.1\|AVQ71951.1\|2438485_2439217_-\|glutathione-peroxidase	unknown	unknown	gnl\|CDD\|223750
CP020664.1\|AVQ71950.1\|2437912_2438446_-\|DNA-starvation/stationary-phase-protection-protein-Dps	unknown	unknown	gnl\|CDD\|236521
CP020664.1\|AVQ71943.1\|2427185_2427593_-\|hypothetical-protein	cmr5gr11	mkCas0065_cmr5gr11_CAS-III-B	unknown
CP020664.1\|AVQ71952.1\|2439587_2440538_+\|undecaprenyl-diphosphatase	unknown	unknown	gnl\|CDD\|234712
CP020664.1\|AVQ71945.1\|2430563_2431547_-\|CRISPR-associated-protein-Cmr3	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	gnl\|CDD\|187879
CP020664.1\|AVQ71953.1\|2440550_2441408_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP020664.1\|AVQ71941.1\|2424398_2425307_+\|transglutaminase-like-superfamily-protein	unknown	unknown	gnl\|CDD\|224224
CP020664.1\|AVQ71957.1\|2443700_2443880_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ71948.1\|2434036_2434639_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368559

Protein	Function_ID	Function_description	E-value
CP020664.1\|AVQ71947.1\|2432989_2434021_-\|hypothetical-protein	gnl\|CDD\|380122	pfam18145, SAVED, SMODS-associated and fused to various effectors sensor domain. Predicted to function as a sensor domain, sensing nucleotides or nucleotide derivatives generated by SMODS and other nucleotide synthetase domains. The sensing of ligands by SAVED is predicted to activate effectors deployed by a class of conflict systems which are reliant on the on the production and sensing of the nucleotide second messengers.	1.75778e-09
CP020664.1\|AVQ71946.1\|2431557_2432982_-\|CRISPR-associated-protein-Cas10	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	2.74201e-26
CP020664.1\|AVQ71955.1\|2441616_2442951_-\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	gnl\|CDD\|235422	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX.	0
CP020664.1\|AVQ71958.1\|2444141_2445539_-\|trigger-factor	gnl\|CDD\|234956	PRK01490, tig, trigger factor; Provisional.	5.00201e-117
CP020664.1\|AVQ71949.1\|2436585_2437869_+\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.6031e-18
CP020664.1\|AVQ71942.1\|2425551_2427180_-\|RAMP-superfamily-protein	gnl\|CDD\|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	0.000121183
CP020664.1\|AVQ71956.1\|2442962_2443664_-\|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.9317e-139
CP020664.1\|AVQ71940.1\|2422761_2424225_-\|GTP-binding-protein	gnl\|CDD\|206646	cd00880, Era_like, E. coli Ras-like protein (Era)-like GTPase. The Era (E. coli Ras-like protein)-like family includes several distinct subfamilies (TrmE/ThdF, FeoB, YihA (EngB), Era, and EngA/YfgK) that generally show sequence conservation in the region between the Walker A and B motifs (G1 and G3 box motifs), to the exclusion of other GTPases. TrmE is ubiquitous in bacteria and is a widespread mitochondrial protein in eukaryotes, but is absent from archaea. The yeast member of TrmE family, MSS1, is involved in mitochondrial translation; bacterial members are often present in translation-related operons. FeoB represents an unusual adaptation of GTPases for high-affinity iron (II) transport. YihA (EngB) family of GTPases is typified by the E. coli YihA, which is an essential protein involved in cell division control. Era is characterized by a distinct derivative of the KH domain (the pseudo-KH domain) which is located C-terminal to the GTPase domain. EngA and its orthologs are composed of two GTPase domains and, since the sequences of the two domains are more similar to each other than to other GTPases, it is likely that an ancient gene duplication, rather than a fusion of evolutionarily distinct GTPases, gave rise to this family.	1.11975e-39
CP020664.1\|AVQ71939.1\|2422238_2422535_+\|plasmid-stabilization-protein	gnl\|CDD\|368240	pfam05016, ParE_toxin, ParE toxin of type II toxin-antitoxin system, parDE. ParE is the toxin family of a type II toxin-antitoxin family. It is toxic towards DNA gyrase, but is neutralized by the antitoxin ParD. The family also encompasses RelE/ParE described in.	4.09698e-07
CP020664.1\|AVQ71951.1\|2438485_2439217_-\|glutathione-peroxidase	gnl\|CDD\|223750	COG0678, AHP1, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	1.59932e-92
CP020664.1\|AVQ71950.1\|2437912_2438446_-\|DNA-starvation/stationary-phase-protection-protein-Dps	gnl\|CDD\|236521	PRK09448, PRK09448, DNA starvation/stationary phase protection protein Dps; Provisional.	8.65904e-89
CP020664.1\|AVQ71944.1\|2427612_2428440_-\|CRISPR-associated-protein-Csm4	gnl\|CDD\|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	5.18019e-23
CP020664.1\|AVQ71952.1\|2439587_2440538_+\|undecaprenyl-diphosphatase	gnl\|CDD\|234712	PRK00281, PRK00281, undecaprenyl-diphosphate phosphatase.	2.03909e-93
CP020664.1\|AVQ71945.1\|2430563_2431547_-\|CRISPR-associated-protein-Cmr3	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	1.68255e-06
CP020664.1\|AVQ71953.1\|2440550_2441408_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.65763e-35
CP020664.1\|AVQ71941.1\|2424398_2425307_+\|transglutaminase-like-superfamily-protein	gnl\|CDD\|224224	COG1305, COG1305, Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism].	5.36471e-37
CP020664.1\|AVQ71948.1\|2434036_2434639_-\|hypothetical-protein	gnl\|CDD\|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	8.92436e-24

>CP020664.1|AVQ71948.1|2434036_2434639_-|hypothetical-protein
MTYLSPKLFTFEDFLNQYGDDPRYQLIDGELRDLEPTGHQESVAGKIAGRLWGEILRLHLPWTIPKNCLLRPESGQATALRPDVIILDEVDFSTEPLWEKQPILTSSPAIKLVVEVVSSNWQDDYARKVEEYSSLGIAEYWIVDFRGLGGISFIGKPKQPTLTIYQLEGDEYQQKLYRLYERISSAVFPELSLCLLDIMP
>CP020664.1|AVQ71947.1|2432989_2434021_-|hypothetical-protein
MLKSLKNVLGNLRQYPYNIIFNPLTNAALAIAAILALIADQFGQGYYLIFLITLALVIIGIWLESQKYDLYKHQAIPLPIVIKIANPADSNKALQSLFNIIETENKYKDHKNNLDQYLNISETDLIFNYSCDIYDQEMLKAFLQILRYNLEKLKKKTPQNTIIYLAYIGPISVAIMVGTILATEGVKIFQYNKSSDSYYPVVEISDRKLKEDIKEYEKFERVVTEKGQDRVTIAIDVSSHKINLNDQSIENYGDLIYLKSKGSGTIEKNEDWLQYSREIFKTINIAQQKNYQEIKLVYSMPITLGILVGMAVQQYWPILLTQYENSTYRNLINLQEFKLYRGQ
>CP020664.1|AVQ71946.1|2431557_2432982_-|CRISPR-associated-protein-Cas10
MNYTVITFAPVQGFIEKSRKLRDLYGGSFLLSYLADAICQAADKYPECSLISPALIDVKRGTPNQILIAGNFPKKEAEQVFNDAWQKVVNKCRVWIEQNLPQYNYTWRREWNLWINHTWEFFWAQEDSIDCAFKSLQQKKYQRDWTGINWQGESSSLSGSDAIVWYGMTDQTHPLYSSISQQNQQITEFYQQLSQKLSNAILDETERLSIPELVKRMITLYDIGKPLNLELPKKFVELNRYEEKSYTGWFQGDGDGMGNYLKNLSISSRKEFSQRMRQWGEELENYLNFGRIIYAGGDDFLGVLFSQKSEPKLTLQDCLYWFDQFHREIWPKHGYSQDITVSVGFVWAASGVPQRDILQQCREAEKSAKNQGKNRLAVRILFNSGNYLEWVCPWENLKDILDIYCDRSEGKNWTHFYNDIATLENRRAFTDDNHDIANAVFNLYFNQNIPIDTTSHQDKNNWVINLSKVANHLT
>CP020664.1|AVQ71945.1|2430563_2431547_-|CRISPR-associated-protein-Cmr3
MLQYLIIIKPLGFLYGSAGPFLSPENLVGRSGNRFPPTAATVSGLFAHSNPTNIRDLQIAGPFWANSEQPDNFFVPTPFIYLAKKPLANYFQDQENNDNGKIQHTLTWQEKWQEKDSKQIEGKFDRDSWIPINQWYNPQKAYGSPWQYHPHLHPRLLEEQRKVKTGELFLENAVQLHPDACLVYLANQPLENGWYRFGGESHLVEVKSLELSSHLQTLFNQDVGQYFALITAAIWGTNRLSTRNPSDWQLETLNTERPITYRYRFGGKDKVKRLSRGRYAVPAGTVYRLKNPLPSWQNWQESWFPSEGVSLKRWGCGLALPLENIAK
>CP020664.1|AVQ71944.1|2427612_2428440_-|CRISPR-associated-protein-Csm4
MYHKSYGILETLAPLHVGATAGEETGNLNLIFRDQFTQTAIIPGSSIRGRFRADMNNIDEKRTWYGHETIPGQEDGGTTEAKVKFEYASLVWLPVFCPGQPIVWVTSPLLLKRYKQITGISAKVPNPYTASPSLQARVVQGVNRNSKVLFFNLGFLEIEHLEELSSWIPPQADLKASQLVVVDDNDISMLHDMALYRQSRVKLLEGQKKVDTEKGAFFNVEALPVGSILVFPIACKETGWQPFGESVNQKELYFGGLESIGFGRCQVTILNYANQ
>CP020664.1|AVQ71943.1|2427185_2427593_-|hypothetical-protein
MAWKEYNLDRIAQKLVLAAKLRDRDSLNQSFKMRESVSYGLERFWGEHLRLQSKEPNKAQYWKETWDKLVETMAEAGIPIPNDTVQVNDTESVQAMAEKLWELKLEDQRITLAVLTQLCDCLVWWTQRYKGTKER
>CP020664.1|AVQ71942.1|2425551_2427180_-|RAMP-superfamily-protein
MVNIPDIGDKIPLMFRAQTKGRSQLQYIDSKKDENDSQKWVKEWIERVDENPPQFGQEVKTKEYQISWRFVTNGGQDEGIIRPVMGAYGIPFYPGSSMKGAFCQACTPEQKQRYHLEKDSDNPSLLRFHGGYPVNDWTENLLDIVHPQQGWQVKTPNTRQKPSGESGFALISLYQPTLKFGISTSIEQPDWEEIWTIWERALESGLGCRVSSGYGLPKDIKPSKEPLYKCFLKGQGMAPKSLDGAREFRPNIFRGAIRGHALRIFGGLTDAKNAEKLVNQLFGGIDGEVTQGLLAVDFCVKSLDLGTFAKGYKEPTYTVTGELRWILTQSLPENQQECLKKLICFLTRFAMLLGGFGKSWRRADHSIFYEDYYPNKPLIGCHWQWGDKSSLINDNKVRDLTHVHPFIKDVRTIAKQWMSLQKDILRTPDNSANWRESWHPKNVEVWGRIAEDKDDSLAIKWLHKAYQKLDNLSIYKTSVTGIVTKNINQVGRLWHRMYPKNNHQYLELLTIFPDDSDDCAYFLGFLDENNGQEGKFQKIWPK
>CP020664.1|AVQ71941.1|2424398_2425307_+|transglutaminase-like-superfamily-protein
MSVIYDLEHITTYHYRKPVTFGEHRAIFLPSAGHGERIISYSVEANIAAKTRWTMDTLSNNVVELEFAEPASELIVTCRLRAEHFGLKAIADFPLAQRAIEIPIQYTPDEWLDLVVFMRPHAEDADGSLAAWAKSFVAGDQDDTLDAMARMMAAIKDNFTYQARESEGTQSPGETLRLKSGTCRDYAWLMIEALRRLGLACRFVSGYLYDAALDGGEVGMTGSGATHAWLQVYLPGAGWRNYDPTNQITAGFDLIRVAIARHPGQIIPLSGSWFGDADDYLSMDVKVTIRKLGTLPDFDPRE
>CP020664.1|AVQ71940.1|2422761_2424225_-|GTP-binding-protein
MTSDPSLDRAWNTEDLEQALRGVGTIQEELNYNQARNSLSKLVERLDLTSIEKIGLEAEIDRLVALLEKLDRSLIQIAAFGLVGRGKSSILNALVGQEIFTTGPLHGVTRTIKGVNWQLSSDDTFPNLARLTLNGQGNAQVQLLDTPGIDEVDGQTREILACQVAQQVDLILFIISGDMTKVEFSALAKLREAGKPMILVFNKIDQYPEVDRLAIYEKIASERVKELLSPDEIVMVAASPLLTDTVKEQDGRLKTQRFRGKPQIEALKLKILEILEREGKSLVALNSMLYADEVNEQIVARKMAIRDRGANQLIQKAVMIKASAIALNPVTVLDLFTGAVIDLAMILALSRLYGIDLTRQGAIALLQKIALNMGGISASEFLAVLGLSSLKGLLGLSIPATGGISLLPYTSIALTQAGVAGVSCYAIGQVTKTYLANGATWGPDGPKAVVASILDSLDETSILNRIKRELGSKLAGGGLFSVAKGTA
>CP020664.1|AVQ71939.1|2422238_2422535_+|plasmid-stabilization-protein
MADRVNYRLVWSPKAIEDVDAIASYISRDSPSYAAAVVRRILDISYSLENCPLEAKKCAEFSDDTIREKSAYAYRLIYQIQGAVVIIAAIVHSKHFLD
>CP020664.1|AVQ71949.1|2436585_2437869_+|serine/threonine-protein-kinase
MLDRVLHSRYQVQQLLGKKTILARDRHTTQLVIIKLISVPRGQGSQFIEEITGKIALLRQLSHPSLPKYLDSFEIDSSQEQIIAIVRPYLSAQPLENYLNSSYLLAEQDLKQIAKYLLEILSYLHQQDVPINHGNIKLSNILFDTQSHRFYLVDFAFDSDSPTTDLQDIGKSLISLATGIKHRYIPENFEQKTNLSAFFIYWLKRLSNSPPDSHFRSVTEALASLYSCQLILVSIGNLTKPYGSEVTVYKKDNLLQIKIASKTKQKFFNNLKTQLRQFLPSLFFTIILLTIVGIYDLKLVAFLIPIILIFLLNLISSSLSWQLWKSFWQGELELKITPKKVSLYQKLWGLKFKLTADAASSEIYSLIRRNVTVTMQGENVNIIPPSLVLVANHREYIITASEDVSEAELDWLAQQLSDWLRLPITRI
>CP020664.1|AVQ71950.1|2437912_2438446_-|DNA-starvation/stationary-phase-protection-protein-Dps
MVATPVKTKTTGQYYATRIDLALDIRKAVVEILSQTLAASLDLKTQVKQAHWNVKGLNFYQLHSLFDEMATELEGYGDMVAERITALGGTALGTARIAAANSILPEYPADIVDGSEHIVALAERYALYAAHLRSAIDTTGNQGDADTADLYTEISRDIDKRLWFLEAHLIKSEDVIG
>CP020664.1|AVQ71951.1|2438485_2439217_-|glutathione-peroxidase
MLPNREGKRVPDVTFPVRQNNQWVNITSEELFKGKTVVLFALPGAFTPTCSTSHLPGYNELAPVFRENGVDTIVCLSVNDTFVMNEWAKDQECDNVVLIPDGNGEFSAGMGMLVDKADLGFGKRSWRYSMLVKDGVIEKMFIEPEEPGDPFKVSDAETMLHYINPEAKKPPLVSLFSKVGCPYCLRAKKMLEEKGLQYEEIILGRDATSRSLRAMSGNTTTPQVFIDGKLIGGSEELAAHLGA
>CP020664.1|AVQ71952.1|2439587_2440538_+|undecaprenyl-diphosphatase
MMFPFLKKSYKWLGLAIITVILAITPAVIAQSTTSAIPLAKINWLQAIFLGFVQGVTEFLPISSTAHLKAIPVFLGWGDPGVTYTAVIQLGSIAAVLSYFWQDLRQISTGMVKAVASSDYRSQDFRLAVGIILGTIPIVFFGLLMKLFIPDLDNSPLRSMTAIACASIVMSLLLGTAEKIGKHKRSFETLRQKDGVLMGLAQALALIPGVSRSGSTLTAGLFMGLERAVAARFSFLLGIPAITLAGLVEFKGVLDQINTSELIPLAIGVISSALFSYLSIAWLLDYLKKQSTWVFVWYRLFFGVTILIGVALGRFS
>CP020664.1|AVQ71953.1|2440550_2441408_-|alpha/beta-hydrolase
MKTQIIDKTITVRGVPHYYEWIRQSESPQKKPVMVFIHGWGGSGRYWRSTAAAICDRFDCLLYDMRGFGRSKLPEKSSDLSYDLEEYALDLALFLDSLEMEKIYLNSHSMGASVATFFITMYPERVVKAVLTCNGIFEYNKAAFAAFHKFGKYVVQFRYDWFLKVPFADRLFMARFLHRSIPKLERIAFLEDFLAADYEAALGTIYTSVSKKAVEIMPGKFAEIKIPTLLVSGEKDIIIPAKMGKMAADLNSNIQYVEMANTAHFPMLEDAPTYLQKLQDFLEIN
>CP020664.1|AVQ71954.1|2441385_2441595_-|hypothetical-protein
MLNTVPAIIKEGRIELLESVPIPEGTRVLVTLIPEETNSDFWQKVSETALAKIWDNLEDDIYHENSNNR
>CP020664.1|AVQ71955.1|2441616_2442951_-|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX
MSKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVELCNEILDEELMEPPSPVAPVEERPNKRRSGQNKTTWEQIPKPREIKKYLDDYVIGQNEAKKVLSVAVYNHYKRLKDIQTQKAGGGSPEDSIELQKSNILLIGPTGSGKTLLAQTLAKILDVPFAVADATTLTEAGYVGEDVENILLRLLQVADLDVEEAQRGIIYIDEIDKIARKSENTSITRDVSGEGVQQALLKMLEGTIANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLDKVIDQRLGKKSMGFIQPGDGQASKDKVAAGLLKQMTPDDLVKFGMIPEFVGRIPVLAALSPLDEEALIAILTQPRNALVKQYQKLLKMDNVQLEFKSDAVLAIAQEAYRRKTGARALRGIVEELMLDVMYELPSRKDVKRCLITREMVEKRSTADLLVHPSSLPSQESA
>CP020664.1|AVQ71956.1|2442962_2443664_-|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP
MLESRSPDYPITSNCRPAIYANTGRNSLANVLPVVIEQSGMGERAFDIYSRLLRERIVFLGTPVDDQVADSIVAQLLYLEAEDPEKDIQLYINSPGGSVYAGLAIYDTMQQIRPDVATICFGLAASMGAFLLCGGAAGKRMSLPSSRIMIHQPLGGAQGQASDIAIQAKEILYIKQRLNTMLAHHTGQPYDRIANDTERDFFMSAVEAKEYGLIDLVISRPELPDPTVPVTSL
>CP020664.1|AVQ71957.1|2443700_2443880_+|hypothetical-protein
MLGCGAFTGKCVSIFSTSVHLLCPKFPPVGRNQLSVISYQLSVISYQLSVLDTASLLGI
>CP020664.1|AVQ71958.1|2444141_2445539_-|trigger-factor
MKVIQEKLPASQIGLEIEIPAETTKNTHEQVVKNLAKSANIPGFRPGKVPRQILLQRLGTKAVKAAVIEELIENCLESALKQEGIESLGNPQLLSKFEDLIAAYEPGKALTFSVSVDVAPTIVLGDYENLSVTAEETVYDPESVENWFKERQEQLATLVPVEDRGAQLGDVAIVDYRGKSAETGEDIPDIDGEDLRVDMETGRFIEGMVEGIVGMKPEEVKEMTLTFPEDYPKEDVAAKAVIFTITMKELKAKELPELDDDFAQEVSDQETIAELRASLEKRFREEAEKETKDSIYDALTQELVKGATLDLPETLIEKEVTHILTQSFMQFQQMGLDVNHLFTKDNIPKMRESTRPDAIESLKQTLVVQELAKVAGIEVSAEAVTEKIAKIMAQLSDRDIDMQRLEQVITEEILAENTLAWLKEKATITLVPKGSLEEETSEEEETEETFAFTEVEVLAAEAEEE

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Crispr_ID: CP020664_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020664_14

2998868-2998964

TypeV-U4

Consensus_repeat	Method
TCAGTAAACAGTAAACAGTAATCAG	CRISPRCasFinder

1 spacers

c2c9_V-U4

The CRISPR arrays of CP020664_14

>merge|CP020664|14|2998868-2998964|CRISPRCasFinder
TCAGTAAACAGTAAACAGTAATCAGTAAACAGTAAACAGTAATCAGTGAGACACTGTTGATGGGAGTTTTTTTCAGTGGTCAGTAAACAGTAAACAG

>CP020664|14|13|2998868-2998964|CRISPRCasFinder
TCAGTAAACAGTAAACAGTAATCAG	TAAACAGTAAACAGTAATCAGTGAGACACTGTTGATGGGAGTTTTTT
TCAGTGGTCAGTAAACAGTAAACAG

Protein	Signature genes	Signature genes Name	Protein_function
CP020664.1\|AVQ72447.1\|2987528_2990993_-\|DNA-methyltransferase	unknown	unknown	gnl\|CDD\|227226
CP020664.1\|AVQ72451.1\|2992371_2992674_-\|addiction-module-toxin-YoeB	unknown	unknown	gnl\|CDD\|284238
CP020664.1\|AVQ72460.1\|3004407_3004788_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227024
CP020664.1\|AVQ72458.1\|3003653_3003836_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
CP020664.1\|AVQ72449.1\|2991687_2991888_+\|prevent-host-death-family-protein	unknown	unknown	unknown
CP020664.1\|AVQ72455.1\|2999869_3000286_-\|YggT-family-protein	unknown	unknown	unknown
CP020664.1\|AVQ72452.1\|2992645_2992978_-\|antitoxin-YefM	unknown	unknown	gnl\|CDD\|376852
CP020664.1\|AVQ72456.1\|3000619_3001483_-\|cyanophycinase	unknown	unknown	gnl\|CDD\|131124
CP020664.1\|AVQ72461.1\|3004952_3005654_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ72463.1\|3006498_3006780_+\|plasmid-stabilization-protein	unknown	unknown	gnl\|CDD\|224937
CP020664.1\|AVQ72462.1\|3006329_3006533_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376852
CP020664.1\|AVQ72450.1\|2991845_2992100_-\|modification-methylase-HhaI	unknown	unknown	gnl\|CDD\|365904
CP020664.1\|AVQ72454.1\|2997957_2998845_-\|CoA-binding-protein	unknown	unknown	gnl\|CDD\|223152
CP020664.1\|AVQ72446.1\|2986224_2986644_+\|YraN-family-protein	unknown	unknown	gnl\|CDD\|376717
CP020664.1\|AVQ72445.1\|2985651_2986029_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371489
CP020664.1\|AVQ72457.1\|3001716_3002013_-\|hypothetical-protein	c2c9_V-U4	-	gnl\|CDD\|284650
CP020664.1\|AVQ72453.1\|2993046_2997651_-\|glutamate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|236968
CP020664.1\|AVQ72448.1\|2991449_2991677_+\|plasmid-stabilization-protein	unknown	unknown	gnl\|CDD\|224937
CP020664.1\|AVQ72459.1\|3004081_3004411_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|372700
CP020664.1\|AVQ74337.1\|3002884_3003361_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|283241

Protein	Function_ID	Function_description	E-value
CP020664.1\|AVQ72447.1\|2987528_2990993_-\|DNA-methyltransferase	gnl\|CDD\|227226	COG4889, COG4889, Predicted helicase [General function prediction only].	2.75797e-25
CP020664.1\|AVQ72451.1\|2992371_2992674_-\|addiction-module-toxin-YoeB	gnl\|CDD\|284238	pfam06769, YoeB_toxin, YoeB-like toxin of bacterial type II toxin-antitoxin system. YoeB_toxin is a family of bacterial toxins that forms one component of the type II toxin-antitoxin system in E. coli whose antitoxin is represented by YefM, found in pfam02604. The plasmid encoded Axe-Txe proteins in Enterococcus faecium act as an antitoxin-toxin pair. When the plasmid is lost, the antitoxin is degraded relatively quickly by host enzymes. This allows the toxin to interact with its intracellular target, thus killing the cell or impeding cell growth. These toxins are highly potent protein synthesis inhibitors, specifically blocking the initiation of translation. In the case of YoeB, it binds to the 50 S ribosomal subunit in 70 S ribosomes and interacts with the A site leading to mRNA cleavage at this site. As a result, the 3'-end portion of the mRNA is released from ribosomes, and translation initiation is effectively inhibited.	5.8611e-30
CP020664.1\|AVQ72460.1\|3004407_3004788_-\|hypothetical-protein	gnl\|CDD\|227024	COG4679, COG4679, Phage-related protein [Function unknown].	1.2967e-27
CP020664.1\|AVQ72458.1\|3003653_3003836_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.33758e-08
CP020664.1\|AVQ74337.1\|3002884_3003361_-\|CsbD-family-protein	gnl\|CDD\|283241	pfam05532, CsbD, CsbD-like. CsbD is a bacterial general stress response protein. It's expression is mediated by sigma-B, an alternative sigma factor. The role of CsbD in stress response is unclear.	3.79773e-09
CP020664.1\|AVQ72452.1\|2992645_2992978_-\|antitoxin-YefM	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	8.60407e-07
CP020664.1\|AVQ72456.1\|3000619_3001483_-\|cyanophycinase	gnl\|CDD\|131124	TIGR02069, cyanophycinase, cyanophycinase. This model describes both cytosolic and extracellular cyanophycinases. The former are part of a system in many Cyanobacteria and a few other species of generating and later utilizing a storage polymer for nitrogen, carbon, and energy, called cyanophycin. The latter are found in species such as Pseudomonas anguilliseptica that can use external cyanophycin. The polymer has a backbone of L-aspartic acid, with most Asp side chain carboxyl groups attached to L-arginine. [Energy metabolism, Other].	2.02436e-109
CP020664.1\|AVQ72463.1\|3006498_3006780_+\|plasmid-stabilization-protein	gnl\|CDD\|224937	COG2026, RelE, Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning].	9.78396e-16
CP020664.1\|AVQ72462.1\|3006329_3006533_+\|hypothetical-protein	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	0.00043307
CP020664.1\|AVQ72450.1\|2991845_2992100_-\|modification-methylase-HhaI	gnl\|CDD\|365904	pfam00145, DNA_methylase, C-5 cytosine-specific DNA methylase.	6.52415e-17
CP020664.1\|AVQ72454.1\|2997957_2998845_-\|CoA-binding-protein	gnl\|CDD\|223152	COG0074, SucD, Succinyl-CoA synthetase, alpha subunit [Energy production and conversion].	9.63184e-79
CP020664.1\|AVQ72446.1\|2986224_2986644_+\|YraN-family-protein	gnl\|CDD\|376717	pfam02021, UPF0102, Uncharacterized protein family UPF0102. The function of this family is unknown.	1.46516e-33
CP020664.1\|AVQ72445.1\|2985651_2986029_+\|hypothetical-protein	gnl\|CDD\|371489	pfam11360, DUF3110, Protein of unknown function (DUF3110). This family of proteins has no known function.	2.05772e-49
CP020664.1\|AVQ72457.1\|3001716_3002013_-\|hypothetical-protein	gnl\|CDD\|284650	pfam07282, OrfB_Zn_ribbon, Putative transposase DNA-binding domain. This putative domain is found at the C-terminus of a large number of transposase proteins. This domain contains four conserved cysteines suggestive of a zinc binding domain. Given the need for transposases to bind DNA as well as the large number of DNA-binding zinc fingers we hypothesize this domain is DNA-binding.	8.24417e-15
CP020664.1\|AVQ72453.1\|2993046_2997651_-\|glutamate-synthase-large-subunit	gnl\|CDD\|236968	PRK11750, gltB, glutamate synthase subunit alpha; Provisional.	0
CP020664.1\|AVQ72448.1\|2991449_2991677_+\|plasmid-stabilization-protein	gnl\|CDD\|224937	COG2026, RelE, Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning].	1.20295e-11
CP020664.1\|AVQ72459.1\|3004081_3004411_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|372700	pfam13744, HTH_37, Helix-turn-helix domain. Members of this family contains a DNA-binding helix-turn-helix domain.	2.39395e-31

>CP020664.1|AVQ72454.1|2997957_2998845_-|CoA-binding-protein
MKWTDKDQIIMQGIDRPLGKYYAARLKAQGTCLVAGVASGHGGEIIAEIPVFDLVAESVAEAGEIRTSLILVPPNQVLDAALEAIASAIPQLIIVTPGVPPLDLVELLKIATTTGTLILGPGSQGVIIPNYLWLGICEPSFYQSGTIGLITRGDRIGDEVAKTLTAAGYGESMAVNLGTDGIIGSNLSQWLQVFEEDDNTEAILLVSQVGGKAEIEAAKYIASAIEKPVIAYLVGLNTAIETNFGDTETIISNQLSYSVAAKNTRKDSLRHFQEAGVTVVEKLADLPASLAKVLC
>CP020664.1|AVQ72453.1|2993046_2997651_-|glutamate-synthase-large-subunit
MAQQNNLKTDNIHQIDPYWGPRWLVEERDACGVGFIADVRGSGSHQLIEQALLALGCLEHRGGCSADQDSGDGSGMMTAIPRDVLAPWFAENGLNMPESERLGVGMVFLPQAAQERADAKAHIEEIVNKYNIKILGWRAVPVRPQVLGRQARENQPYVEQILVTSPDLAGSQFDRLLYIARSEVGKQLADDFYFCSFSCRTIVYKGMVRGEILREFYLDLQNPAYSSQFAIYHRRFSTNTQPKWPLAQPMRLLGHNGEINTLLGNINWMSAREPALETQGWTHEELQSLTPIVNPANSDSYNLDSALELLVRTGRSPLEAAMILVPEAYNNQPDLQNYPEIIDFYEYYSGLQEPWDGPALLVFSDGGIVGACLDRNGLRPARYSITNNGYIVVSSEAGTIPLDETTIMEKGRLGPGQMIAVDLEKGEIKRNWPIKQEIARANPYGAWVKSQRTFIDKETAIDIPTPSNLLPLQTAFGYTSEDVDLIIVPMAEQGKEPTFCMGDDTPLAVLSSKPHLLYDYFKQRFAQVTNPPIDPLRESLVMSLTMYLGRRGNILKLGVDDAHLLKLDSPLLNNAELAKVKTSSYKTAELSTLYDLTTGPGGLEDAIANLCAEAAKKVASGAEILILSDRTAPIDEKTSYIPPLLAVGAVHHHLIRSHLRLKASIVIDTAQCWSTHHFACLIGYGASAVCPYLALETIAQWWIEPRTQKLMENGKLEAISLEKALINYRKSVEAGLLKILSKMGISLLSSYHGAQIFEAIGLSADLVKLAFNGTTSRVGGLSIAEVAQEAIAFHRQAFPNLTAKKLENYGFVNYRPGGEYHMNSPEMAKALHKAVAAHSQGQGYDHYETYRQILQQRPATALRDLLEFNSDRASIAIEAVESIESILQRFCTGGMSLGALGREAHETLAIAMNRIGGKSNSGEGGEDPIRYTSLSDVDAEGHSVTMPHLNGLKNGDTANSAIKQIASGRFGVTPEYLMSGKQLEIKMAQGAKPGEGGQLPGKKVSPYIAMLRRSKPGVTLISPPPHHDIYSIEDLAQLIYDLHQINPRAKVSVKLVAEIGIGTIAAGVAKANADIIQISGHDGGTGASPLSSIKHAGSPWELGVTEVHRMLMENQLRHRVILRADGGLKTGWDILMAALMGAEEFGFGSISMIAEGCIMARVCHTNNCPVGVATQQERLRARFPGIPAHVVNFFTLVAEETRQLLAKLGYHSLNEVIGRADLLKVRSDARLTKTESLNLDCLLNLPDGRGDRSWLQHEEVHSNGAVLDDDILADSEIKQAIEQQETVSKTYRIVNTDRSVGARIAGVIAQKYGNDGFEGEIKLNFQGAAGQSFGAFNLPGVNLHLEGEANDYVGKGIYGGEIVILPPQNANYQPEDNAIIGNTCLYGATGGVLYANGRAGERFAVRNSTAKAVIEGAGDHLCEYMTGGVIVVLGSVGRNVGAGMTGGLAYILDPSLPEKLNPEIVKIQRVGTAAGAEQLKSLIEAHVERTNSPKGKLILANWDSYLGQFWQVVPPSEADSPEAQISAEKTLTSV
>CP020664.1|AVQ72452.1|2992645_2992978_-|antitoxin-YefM
MAMLPIPTTYTSYTQAQEHFLQVLEQVELGNSIVIVQRQGHHDVALIAADELSALLEEVYLLRSPANAQRLFQSLNWSQERLSQTAATTSLEELRQELETEIEQEKAAEV
>CP020664.1|AVQ72451.1|2992371_2992674_-|addiction-module-toxin-YoeB
MSKKKPQKSETEIVRVCPEFAPQFREDLRWWARNNPQIWERLWDLIEAILAEPFSGIGKPEPLKHLGSNLWSRRINLEHRLVYQVENNRILFLQARYHYE
>CP020664.1|AVQ72450.1|2991845_2992100_-|modification-methylase-HhaI
MTNEKLRFIDLFAGIGGFRLTFERVGYDCVYSCEIDENCRKVGKQAGFRDTRGTLFFPICEIVELKQDTSNQSIFSIFLTSSRE
>CP020664.1|AVQ72449.1|2991687_2991888_+|prevent-host-death-family-protein
MIELHPEFLIKNGKKEFAVLTYEEFVKIKEILEDLEDLEDLIQAKEEEKDSQTYSLDEVKKMLNID
>CP020664.1|AVQ72448.1|2991449_2991677_+|plasmid-stabilization-protein
MKYQIQFKPKAIKDLEKLSSQDRTRIMAKIEAMKDNLQGDVKQLKNFTPNYRLRVGNYRILFEVEEITLKYLQLN
>CP020664.1|AVQ72447.1|2987528_2990993_-|DNA-methyltransferase
MNPLVNYFRNLQEIHSSQAAVKETSYYGTLETLLNEIGKTLKPRVRCIINLRNQGAGLPDGGLFNVDQFPKNQELEPFTAIFPERGAIEIKGTKEDVKKIAASEQVQKYWQKYGQVLVSNYRDFLLIGRNSQGQPVELEAYSLAPSEAEFWLKTSNPSKFAAEHGDSLLEYLKRVLLQAAPITSPADVAWFLASYARDAKARLERHSDLPALANIRQALENALGIKFEREQGNKFFRSTLVQTLFYGLFSAWVLWHKQNLNREDKEDKFDWKSAAHHLHVPMLAILFEQIAAPSKLKSLGLVEVLNWTGAALNRVRREEFFRQFDEGQAVQYFYEPFLQAFDPDLRKELGVWYTPPEIVRYMVARVDRVLREELNIEDGLANPDVYILDPCCGTGAYLVEVLRYITDTLQENGAGALAMALVKKAAIERIFGFEILTAPFVVAHLQLGLFLQSLDVPLIEDSERVGIYLTNALTGWQPPDEESKQKIQQLQLSFPELNKEREAADEVKRGKPILVILGNPPYNAFAGTSPAEEAGLVEVYKQGLISDWGIKKFNLDELYVRFFRLAERCISENTGKGVVCYISNFSYLGDPSFVVMRQRFLQEFDRLWFDCLNGDSRETGKLTPEGNPDPSVFSTQYNKEGIRVGTTIGLMVRKEVRNKNVDVYFRHFWGVAKREQLLDSLNNQDFDAFYQVSNPEQSNRYSFRPSDVSSHYLAWPKLTDLSDEAPITGYKENRGYSFIDSDKTILSERISKYFDQNISWEELASLNTGLTKDAARFDAKKARDKVLKLREKFNPQMLLPYLLRPYEIKWCYYTQIRPLWNESRPSLFIHQFQGNSFLVSRPAGVASPEGIPFYFTNCLGDFDFIRGHAYHFPIRLRQNSEKVNTEDNTQGKLFDSSNFNSPSIKANLSEKSRQYLNQLGINNLDENIENASLIWLHSLAIGYSPLYLGENADGIRQDFPRIPLPNSQELLIKSAQLGQAIASLLDTENPVIGVTKKPTPALQKIALISCTDGGNLNPDKGDLIINVGWGHGGKNGVTMPGKGKAIARQYTTAEMSVISPEMRKLLGTKTYDIYLNDRAYWQNIPARVWEYTIGGYQVIKKWLSYREEKLLGRGLTIAEVQEVSEMTRRITAIILLESDLDDNYQNIKTAVYSF
>CP020664.1|AVQ72446.1|2986224_2986644_+|YraN-family-protein
MTTVGELGENLVADWLQLQQWHILQRRWRSGSGEIDLIVLSKSQAILAFVEVKTRSAGNWDLGGKLAIDDRKQGKIYEAAQIFLSFYPQWSDLTCRFDVALVSCQKSSLFALPEFSLDYPCQLRAGYQLQLQEYLVAVF
>CP020664.1|AVQ72445.1|2985651_2986029_+|hypothetical-protein
MRVFVLLFNAGTENEGIHTIQMGAINKVLMFESEDDATRYALLLEAQDFPTPTVEKIDSEEVAEFCRGAGYQAEMIEAGMLVIPPESNASELDWQKEEVPPAEEEFSEIPDAELDSIRRRLEGLL
>CP020664.1|AVQ72455.1|2999869_3000286_-|YggT-family-protein
MNHDRDDETNLERRRELLHDEEAFRLDQEEKRLRSARRSNTLNWIINSIFGLAGIVQILLVMRFLLRLFGANPQNQFAQLINHLSAPFIAPFSTLFISPASSGGANIFDVNIVIAIVAYALLSYTLHGYNLHFFLKSL
>CP020664.1|AVQ72456.1|3000619_3001483_-|cyanophycinase
MESTKERGQLIIIGGAEDKEGDCQILREFVRCAGGTKAKIAVLTAATSEPRSAGEAYTRVFERLGVEDVCVLNTIHREDADDPENLKIIEEATGAFFTGGDQALIIEHIKGTQLDTLLHQRNREGMVIGGTSAGAAIMPDLMIIEGDSETNARMDAIEMGPGMGFLHSVVIDQHFAQRGRLGRLISALLQQPANLGFGIDEDTAVVVDGDEFKVLGRGAITVVDESEATYDNLDELLKDEAMAVCGVRLHILPQGFRFNLKTRKPVFSRSIELKDSNPKKEAEVERE
>CP020664.1|AVQ72457.1|3001716_3002013_-|hypothetical-protein
MLNSLISKGLTVPHRCEKRYRWFPSSKRCNNCGHIVEKMPLSVREWECPECGTCHDRDVNASKNILAAGLAVSVWVASVRPEQSKSVKATAKKQKPRS
>CP020664.1|AVQ74337.1|3002884_3003361_-|CsbD-family-protein
MSLQQIRRFFVTIILTIMLAITIAFDFGTTNSWAATLPTQSQTQIASMNRAKAVTKNIEGKAQEAIGNMTGDPKDQMMGKAKQVESQARNAAEDIKDQMKLKGRAKAVTKNIEGKAQEAIGKATGNRQDQVAGKAKQVESQVRNAVEDVKDTVQDILN
>CP020664.1|AVQ72458.1|3003653_3003836_-|CsbD-family-protein
MSLKDRAEATAKNIEGKVQEAVGDLTGDPKAQAEGKEKQAEAKVRHTIEDVKDEVKKIID
>CP020664.1|AVQ72459.1|3004081_3004411_-|XRE-family-transcriptional-regulator
MSYLEITRGTTNVFADLGYPDATERQTKTRLALAVNELLKSRKLKQREIAILLNIPQPKVSALKNYRLDQFSVERLMEFLTALNQDVEIVIRPRSDTKEVGHISVLAVQ
>CP020664.1|AVQ72460.1|3004407_3004788_-|hypothetical-protein
MIRISKSMSREKPLYWVASAKKDYLTFPAEVQDDMGYALGLAQLGGKHPKAKPWKGEGAGVFEIVEDHRGDTYRAVYTVRFAEVVYVLHAFQKKSKSGIKTPQEDVKLIVERMKRAQADYESRGTK
>CP020664.1|AVQ72461.1|3004952_3005654_-|hypothetical-protein
MNFNKIILVTGLAVSGIALSGVFAPAHAAFFQNTFGLSDSHSTITFGSQDYPDGTTITNQYQNQGVVFSPNMFYFSNNGGSIVPPTPPVFVGAVVTNFIPHDGTVAPVVISFTQPQTEAAFAVGTQSGTTTYFEAFLGTNLVDSSGATNADSLSNDFFGFSGITFDSIKISGSVRLVFALDNIQLPTAPVSSSIPEPSSILGIIAFGTLGAGAILTRKIKPSKSTGKELEKDS
>CP020664.1|AVQ72462.1|3006329_3006533_+|hypothetical-protein
MTTQPKDPEIVLRDGKPVSVILDIEVYQEMLEQIEAIEDLKALAEMRQKPLEFRSLDDFLKDYSTDV
>CP020664.1|AVQ72463.1|3006498_3006780_+|plasmid-stabilization-protein
MTFSKIIQRMYEVLLEKQAERDLRKLPADLFERIIPVIRALNTNPRPSGCLKLKNSLQDYRVRVGEYRIIYEIDDKNQVVKVMRVRHRRESYR

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Crispr_ID: CP020664_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020664_15

3416394-3416485

TypeV

Consensus_repeat	Method
CTGTTTGGTAAACTTTTCTAGTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020664_15

>merge|CP020664|15|3416394-3416485|CRISPRCasFinder
CTGTTTGGTAAACTTTTCTAGTTCTATAGATAAGGTAGGTTGGGTTGACGCAAGGAAACCCAACGCCCGCTGTTTGGTAAACTTTTCTAGTT

>CP020664|15|14|3416394-3416485|CRISPRCasFinder
CTGTTTGGTAAACTTTTCTAGTT	CTATAGATAAGGTAGGTTGGGTTGACGCAAGGAAACCCAACGCCCG
CTGTTTGGTAAACTTTTCTAGTT

Protein	Signature genes	Signature genes Name	Protein_function
CP020664.1\|AVQ72794.1\|3406306_3407134_+\|nitrate-ABC-transporter,-permease-protein	unknown	unknown	gnl\|CDD\|130251
CP020664.1\|AVQ72802.1\|3416509_3417415_+\|peptidase-S1	unknown	unknown	gnl\|CDD\|379142
CP020664.1\|AVQ74360.1\|3422930_3423116_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ74359.1\|3413374_3414022_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371771
CP020664.1\|AVQ74358.1\|3409356_3410355_+\|bacitracin-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|130252
CP020664.1\|AVQ72803.1\|3417444_3418650_+\|V8-like-Glu-specific-endopeptidase	unknown	unknown	gnl\|CDD\|379142
CP020664.1\|AVQ72807.1\|3421937_3422252_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ72796.1\|3410728_3412465_-\|serine/threonine-protein-kinase-pkn1	unknown	unknown	gnl\|CDD\|224182
CP020664.1\|AVQ72804.1\|3418671_3419280_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ72798.1\|3412797_3413034_-\|HicB-family-protein	unknown	unknown	gnl\|CDD\|224514
CP020664.1\|AVQ72809.1\|3423178_3423571_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ72810.1\|3423647_3425783_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226428
CP020664.1\|AVQ72805.1\|3419328_3420555_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ72808.1\|3422534_3422930_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237030
CP020664.1\|AVQ72799.1\|3414095_3414332_+\|NifU-family-protein	unknown	unknown	gnl\|CDD\|376458
CP020664.1\|AVQ72800.1\|3414531_3415620_+\|isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|333905
CP020664.1\|AVQ72793.1\|3404851_3406174_+\|bicarbonate-binding-protein	unknown	unknown	gnl\|CDD\|372585
CP020664.1\|AVQ72795.1\|3407302_3409309_+\|bacitracin-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|130252
CP020664.1\|AVQ72806.1\|3421143_3421647_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ72797.1\|3412562_3412805_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377942

Protein	Function_ID	Function_description	E-value
CP020664.1\|AVQ72794.1\|3406306_3407134_+\|nitrate-ABC-transporter,-permease-protein	gnl\|CDD\|130251	TIGR01183, Nitrate_transport_permease_protein_NrtB, nitrate ABC transporter, permease protein. This model describes the nitrate transport permease in bacteria. This is gene product of ntrB. The nitrate transport permease is the integral membrane component of the nitrate transport system and belongs to the ATP-binding cassette (ABC) superfamily. At least in photosynthetic bacteria nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA, ntrB, ntrC, ntrD, narB. Functionally ntrC and ntrD resemble the ATP binding components of the binding protein-dependent transport systems. Mutational studies have shown that ntrB and ntrC are mandatory for nitrate accumulation. Nitrate reductase is encoded by narB. [Transport and binding proteins, Anions].	1.12272e-112
CP020664.1\|AVQ72802.1\|3416509_3417415_+\|peptidase-S1	gnl\|CDD\|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	3.24462e-22
CP020664.1\|AVQ74359.1\|3413374_3414022_+\|hypothetical-protein	gnl\|CDD\|371771	pfam11866, DUF3386, Protein of unknown function (DUF3386). This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are about 220 amino acids in length.	4.3442e-123
CP020664.1\|AVQ74358.1\|3409356_3410355_+\|bacitracin-ABC-transporter-ATP-binding-protein	gnl\|CDD\|130252	TIGR01184, Nitrate_transport_ATP-binding_protein_NrtC, nitrate transport ATP-binding subunits C and D. This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other].	1.66243e-138
CP020664.1\|AVQ72803.1\|3417444_3418650_+\|V8-like-Glu-specific-endopeptidase	gnl\|CDD\|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	2.00817e-20
CP020664.1\|AVQ72808.1\|3422534_3422930_+\|hypothetical-protein	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.00271264
CP020664.1\|AVQ72796.1\|3410728_3412465_-\|serine/threonine-protein-kinase-pkn1	gnl\|CDD\|224182	COG1262, COG1262, Uncharacterized conserved protein [Function unknown].	3.97654e-75
CP020664.1\|AVQ72798.1\|3412797_3413034_-\|HicB-family-protein	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	1.83945e-06
CP020664.1\|AVQ72810.1\|3423647_3425783_-\|hypothetical-protein	gnl\|CDD\|226428	COG3914, Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones].	8.75948e-146
CP020664.1\|AVQ72799.1\|3414095_3414332_+\|NifU-family-protein	gnl\|CDD\|376458	pfam01106, NifU, NifU-like domain. This is an alignment of the carboxy-terminal domain. This is the only common region between the NifU protein from nitrogen-fixing bacteria and rhodobacterial species. The biochemical function of NifU is unknown.	2.08861e-35
CP020664.1\|AVQ72800.1\|3414531_3415620_+\|isocitrate-dehydrogenase	gnl\|CDD\|333905	pfam00180, Iso_dh, Isocitrate/isopropylmalate dehydrogenase.	9.07273e-46
CP020664.1\|AVQ72793.1\|3404851_3406174_+\|bicarbonate-binding-protein	gnl\|CDD\|372585	pfam13379, NMT1_2, NMT1-like family. This family is closely related to the pfam09084 family.	1.70942e-118
CP020664.1\|AVQ72795.1\|3407302_3409309_+\|bacitracin-ABC-transporter-ATP-binding-protein	gnl\|CDD\|130252	TIGR01184, Nitrate_transport_ATP-binding_protein_NrtC, nitrate transport ATP-binding subunits C and D. This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other].	1.32478e-151
CP020664.1\|AVQ72797.1\|3412562_3412805_-\|hypothetical-protein	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	1.35726e-12

>CP020664.1|AVQ72800.1|3414531_3415620_+|isocitrate-dehydrogenase
MTENIPTIVVMHGDQTGEELLLEALRVLQPSIIRQPLNFADFDLSLAQRRQSNNQVVHEAAEATLKTGLALKAATITPEIKGDVGSPNAILREAMNSQVILRIGRRIPGIRPIGGVYSPIAIVRMAVDDAYGAKEWRETTATGDEIAYRTSRISRATSRAVAEFTFQHAKKTGARVFGGPKFTVSATYEGMFKEELDAAAQRHPEVRYQPLLIDATFALLLQTDGEALVIPALNRDGDLLSDFVLQLYGSIAGAESLVLGFDEETLAVKTIMAEAPHGTAPALEGKNIANPMAMILASAALLGYIETNEARKASRAIYESVFETIHEGKKTPDLGGQMTMSEFTDEVIRRVVSKLEVWSALG
>CP020664.1|AVQ72799.1|3414095_3414332_+|NifU-family-protein
MSLTLTPDNVEKVLDEMRPYLMSDGGNVELVEIDGPVVKVRLQGACGSCPSSTMTLKMGIERRLREMIPEIAEVEQAF
>CP020664.1|AVQ74359.1|3413374_3414022_+|hypothetical-protein
MTVATTNARDIFRSAYENRYTWDERFPGYTADIILTQGEEVHTGKIQVNADYSVEVTGIDDEKVQESIYNQMRDIVTHRKRGNFEASHGKNQFNFGQDDPTGAVEILVTGDAMGSNYKVRGQEICQVSRVMGPMAFTINTEESLDTGEGYISIRYNAIFRNAKTDELKGKRDFKETYEKIGNYYLPSCQVINAIDVGGEKSTTEFTFINLQLLES
>CP020664.1|AVQ72798.1|3412797_3413034_-|HicB-family-protein
MTKLSPKVTAIIRSGEQQGYVGECVEISIVTQGNTLDEVVNNLQEAILLHLEGEDPREFGLVAKPSLQIIFELQPEYA
>CP020664.1|AVQ72797.1|3412562_3412805_-|hypothetical-protein
MPKLKQLSGKDIIKILDRFGFTIHSQRGSHIKLRRVISERKETLTIPNHRQLDPGTCYAIFRQASQYIPESELYPYFYDL
>CP020664.1|AVQ72796.1|3410728_3412465_-|serine/threonine-protein-kinase-pkn1
MAEETAKIKLYRKTYQLPQLNRPDLLVLQDQIQERQQLMKTGKRVRNTWLGLSKKEEPLNFEETFQELERLVGDYNQLIGFLTDHKDEYRRFFLSLTEEIKEAVAVKCHKLAETERKRQSLENSIGSAELRDTLRLQKQQIFRTVILVGRASLLMLKKIDLISESIQKLAEDQDTQKQVFSKMIGELNGYKQVYQLQLELDSLEKEAIEMVKVAINLEQYLKPIIGQFQGLIDRVVTIDGELSRSVSEVESLVQNILSSESAVSFRKNENLSASLLNFLVTSEEKRGRLAIALERAEQEGWQWTDVEIPDEEIELETAIQRINNHVIERVGNFTTSTENLPNGITLKMVSLPAGQFLMGSPDSDPDARDNEKPPHQVQVNGFAIGKYPVTQAQYEAVMGTNPSRFQNNPQNPVEKVSWEDAQAFCQKLSQITGKTYRLPTEAEWEYACRGGTTTRYYFGDDANQLGDYAWYNGNSQDKTHPVGQKKPNAWGLHDMSGNVWEWCEDDWHDNYIGAPTDGSAWITNNNDNDYDYRIPRGGSWFTDPNLCRSACRNYNYRRAYVSSAYGGFRVVCGAGRTL
>CP020664.1|AVQ74358.1|3409356_3410355_+|bacitracin-ABC-transporter-ATP-binding-protein
MQTFTDKTVNSSTTTQPFLLVSNVAKEYPSPEGVYTVLDGVELQVNEGEFVCIIGHSGCGKSTLLNMVAGFSSPSRGQVLLQDKEVKEPGPDRMMVFQNYSLLPWKTAFENVYIGVNSVYPEKSQAEKVKIVEENLSLVGLTEAAQKKPPQLSGGMKQRVAIARALAIRPQVLILDEPFGALDAITKEELQEELLKIWQEHQLTVLMITHDIDEALFLCDRLVMMTNGPSAKIGEVLKMPFARPRVRSQITEDPRYYELRNEALDFLYNRFAHSEDPNEDAPEQPPTENLVGKIVTTIGGIALLAFVGFSLIQMFTSKTANTTNPATIEAPR
>CP020664.1|AVQ72795.1|3407302_3409309_+|bacitracin-ABC-transporter-ATP-binding-protein
MSAFIEVDHIDKVFPLPDGRQYIALKNIDLSVTKGEFISLIGHSGCGKSTLLNMVAGLDRPTVGGVILEGREIKDPGPDRMVVFQNYSLLPWLTVRENIALGVNRVLRHLPAAERKSVIEHSIDMVHLRHAANKRPGELSGGMKQRVAIARALALRPKVLLLDEPFGALDALTRGNLQERLMEIVEESHVTCIMVTHDVDEALLLSDRVVMLTTGPEAHIGQILDVPIPRPRHRLEVVNHPSYYSLRNEIVYFLNQQKRAKKVGQPTGAVTLIGQATGLKTNPTIGFIPLTDCAPIIIAKEKGFFAEEGLENVVLQREPNWKALAQGVATGRLDAAQMVAGMPLSMTIGAGNKPSVPVISALVLSRNGNAITLSNKYRELGVEKLEDLKGALLQSPDKIATFGMVHPASMHNLLLRYWLASGGIDPDSDVNLAVIPPPQMVSLLKAGNIDGYCVGEPWNSYAVHEKLGYVIATDLDIWPGHQEKVLGVRETWAAKHPETHIAMVKALIKACEYCDDRRNREEIVNILSQPQYVGVDRAIIRPGFLDGYDRGLGTAPEPLFRFNQFYVDQANCPGRSEALWTLTQLARWGYAPFPRNWVEVIERVRRPDLFGEACRSLGLPDLEPDRHSFALFDHLIFNPDDPIGYLERFSIRRDYRVSEVLLDDPVTN
>CP020664.1|AVQ72794.1|3406306_3407134_+|nitrate-ABC-transporter,-permease-protein
MAVSISRRSQGTKWVKDLKKKLSKLATSAIALLIFLLLWQIICFSPDAPLPSPTKVVSDTWELIINPFFNNGGTDVGLFWQIFASLQRVAVGFTLAAIVGIAVGILIGSSALIYDAIDPIFQILRTVPPLAWLPISLAAFRNNEPSAIFVIFITAIWPIIINTAVGVQQVPQDYKNVSRVLKLSKVEYFFNILFPATVPYVFTGLRIGIGLSWLAIVAAEMLIGGVGIGFFIWDAWNSSMISEIILALIYVGIVGFLLDRLMAYIAKLVVPEENK
>CP020664.1|AVQ72793.1|3404851_3406174_+|bicarbonate-binding-protein
MSKLSRRRFIFTAGATAVGTAILHGCATPNNTATSPSPAGSPAASPAAGGETPEVTTAKLGFIALTDSAPLIIAKEKGLFAKHGMPDVQVMKQASWAATRDNLELGSAGNGIDGAHILSPMPYLMTLGKITKQPVPMYILARLNTNGQAISVANEYMDLKVALDSGVLKESFAKAKSAGKEVKAAVTFPGGTHDLWMRYWLAASGIDPNKDLSLIVVPPAQMVANMKVGTMQAFCVGEPWNAQLVNKKLGYSALITGELWKDHPEKAFALRADWVDKNPKAAKALTMAVLEAQQWCNDPANVKEMCEIISGREWLKIDPADILGRMQGNIDFGDGRKIENSPVAMKFWADNASYPYKSHDTWFVTEDIRWGYIPADTDIKALVDKVNREDIWREAATALNVPADQIPTSTSRGVETFFDGVKFDPENPTAYLKSLKIKKV
>CP020664.1|AVQ72802.1|3416509_3417415_+|peptidase-S1
MSRPIKRILAGAGSLLLGLSTPLLAVQSYAPALEPNQANAHSSQQLSEQQLRQSARAITVKVLSGQGWGSGILVEKQGSSYKVLTNDHVLGRYRSRVWQIQTPDGKIHRGELVRTVRLNDYDLGLVSFRSSQVYSIADLANVDDLTIGDEVFAAGYPFDFTFTVGKVSLLSDKSFSGGYQIGYTNKIKNGMSGGPLLNRQGKVIGINGIHAYPLWGKSYVFADGTVTSPALWEQMSRLSWAIPIGTFLKSGSSSPSASSRQRPAVSPPPLPTHREPTFWEDFPSPSSSTPREKNPAPTPLW
>CP020664.1|AVQ72803.1|3417444_3418650_+|V8-like-Glu-specific-endopeptidase
MSNNFLKISAALVSIAVFVVSPQIAKASTTEEIEKIAEKITVLIPSEEEGANGKITSNGSGSIIAKEGRVYTVLTASHVICKDARDACKFYYDQLKIITWDGKQYPLDYNSIKKLPGVDLALVQFQSDQNYQLATLGNYQVADEQFIFASGWPDPKFIGKRKRLFNLGKVLPKDITPLLKIFPPELGYEIVYTSVTYGGMSGGPVLDINGRVIAVHGQNEAEKIEKVPVPIGFSLAIPITTFLKLAPQSGIQGQINVESSPPNALSLREIGDELYKAFEVPNNNDTNPLNWLNQGNKMWRLGQLALAYAAYEKALQLDAQLYQAWYGKGLLLTYWKRHQEALAAYEQALKINPDSDTAKKLRDKLQESLGGGNTPSLTPSQPTTAPTVEPSPQPSNPRRLW
>CP020664.1|AVQ72804.1|3418671_3419280_-|hypothetical-protein
MLMKWLTNWQVSLVAAVLLTNSLVSPVMAQTGNQSDITGPILSTSDFAGQTISLPITTTVTGLGFQGGEPAQISVNQTAASVNTQLADNNLTSPTGIPIPPTVQQPILSILTADAQAGNNITAVTAALTTVPGAPPLSVIQNLLDGLNGLTSGGAVNPANLLAAVQTYNEMILASNEAFLASPPAELRAIQASLAALVEAAR
>CP020664.1|AVQ72805.1|3419328_3420555_-|hypothetical-protein
MLLKKAKRNSQMRHIFSGGIFITSCLGTAILCDGVKAIPSPLDIDAASIRVSQEKITINSPVELERTDRILTTNSFSTTEGLADSNLPSSLENKPEKSSLDTLATEKTGTISTLEEWKANLGTTRASQLLPAGDNNSPEVEKWQAQASTPVDTNVSPELQRLRQEFLIEEPQLRQQTLSAKLAEFVVTPSGSISTPSAFGATFGQIFGGFGFQSRTRFTNQADGGLALGGGLGDPQKIVGLDVTLAILSLFDDNAGRGSFSFKIHRSLPESFAVALGFENAINWGGTDGGSSIYGVVSKFFQLTKTTKEPFSQLTLSLGVGGGRFRSEGAIEDGVNSLGVFASAGLRIVEPVSAIVEWSGQDLNAGISLIPFPKIPLTVNLAGADLTGNAGDGARFVMSIGYNYFFPR
>CP020664.1|AVQ72806.1|3421143_3421647_-|hypothetical-protein
MKTFVERYRSWFNWTTLAMVVLGFWLSASFVIDLIILPSLSVAGMMTQNGFASAGYLLFGIFNHLELVCAAIVLCSFVVFHRYHTLIHLPEHRSLLFAGVLFVITLIYTYFLTPNLSAMGLLAPVTASGMSGEMMSLQIGYWFLEVVKGLIAFTLLRWCWRDAFKLA
>CP020664.1|AVQ72807.1|3421937_3422252_+|hypothetical-protein
MDKDFRNYRMVCTLTFGDIYGQIIVWLIVIFLTLASTLALWSSTRQIFALATVGLVVVLSLPFLLFAFVTTLLNHIEFVPIEAETNIRRGPVPGVSGSRVPAAS
>CP020664.1|AVQ72808.1|3422534_3422930_+|hypothetical-protein
MLKNLFGGKKSDFYLELKETDGEQQATATTAAAAPIVEAPAPVVESAAAPVAEKKNQKTSIKKEKQVKETPAAPVSAPAPVAATNGKVEPQEVEFATKYLITPSMSRRRPGPSLNGFKDMARKAKLPANRG
>CP020664.1|AVQ74360.1|3422930_3423116_+|hypothetical-protein
MPSDCFLNKKKGESKKALLFHQGASTDSSVAESFFEVGYLGYCLEYFGDNYHLSSWAIFKT
>CP020664.1|AVQ72809.1|3423178_3423571_-|hypothetical-protein
MTAATEKDLKRLEDLIIGIANGQKAIENRLTSMENRLTTLENGQKNLELGQSEIKGDIRTLDAKIEGLSDRVKVIENAAGKTTDLAEKVGELKNWKQIGVVVITASLSSILSGVTGGVIGWLIRAAKVNP
>CP020664.1|AVQ72810.1|3423647_3425783_-|hypothetical-protein
MWHPDAYQALIAENYRQVAAIYEELIDNNPENISDYWYLGVAYLLQNLEAEAQVMWQNVLREGNLEEVKQWQAELEAVLDAEARRQQRKGDLAAVEYFRYHLQEIVPKSINNLLALFDLALDLEIFAPGELLNYPIQENLRSNPDRELLLNVVLKSLLYPHELTLDLAQASLPYLGELADSFIPQAFQIAARVTKEQQSPAFGVEIIKLCLQLRPNDLSLLEQLVNLYILAEDFDNSLITAYQLREICLTPTLKLYSNYLILLILLRWGVWQEIDHIYQEYQNLLQELTRRKNITLEPIIKTSFLNVSSPLPYLGDRALANRQLTNRIAEIFLDNNSLKTPFITIKKAPEKLTIGYLASTLKHHSVGWLSRWLIHHHDREKFQIAIYTINQEEDEITRQWFRDSRDIIRHFPYAQNPLEVAQQIQQDRIDILVDLDSLTHNLTNQIIALKPAAKQVTWLGWDASGLATIDYYIADPYVLPQQAKEYYREKIYRLPETYLAVDGFEIGTPNLRREDLEIPPDATIYFSVQSGMKRHPDTIKLQMKIIAQVPNSYFLIKGVGKTEKIQELFTEIAIREGVNPQRLRFLPRDIDEYTHRANLQIADVVLDTYPYNGATTTLEVLWQGIPLVTLVGEQFSARNSYTFMINAGIEAGIGWNEAEYIDWGVKLGLDRSLRQDISHQLLGNRDTAPLWQGKKFAQNMENAYLKIWQGN

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP020664_16

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020664_16

3527877-3527961

Orphan

Consensus_repeat	Method
ACCTATCGCTGAAACCCTAGATTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020664_16

>merge|CP020664|16|3527877-3527961|CRISPRCasFinder
ACCTATCGCTGAAACCCTAGATTTTTTATCCGAATGCTTCGCCCCTACCCCTGAACAATAACCTATCGCTGAAATCCTAGATTTT

>CP020664|16|15|3527877-3527961|CRISPRCasFinder
ACCTATCGCTGAAACCCTAGATTTT	TTATCCGAATGCTTCGCCCCTACCCCTGAACAATA
ACCTATCGCTGAAATCCTAGATTTT

Protein	Signature genes	Signature genes Name	Protein_function
CP020664.1\|AVQ72907.1\|3528504_3528750_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|312506
CP020664.1\|AVQ72914.1\|3537712_3540349_+\|DNA-topoisomerase-I	unknown	unknown	gnl\|CDD\|236048
CP020664.1\|AVQ72901.1\|3525043_3525922_-\|peptide-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
CP020664.1\|AVQ72913.1\|3536668_3537283_-\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|253548
CP020664.1\|AVQ72904.1\|3526779_3527859_+\|TIGR00303-family-protein	unknown	unknown	gnl\|CDD\|235300
CP020664.1\|AVQ72897.1\|3522411_3523206_+\|flagellar-assembly-protein-H	unknown	unknown	gnl\|CDD\|227751
CP020664.1\|AVQ72900.1\|3524635_3524998_-\|thiol-reductase-thioredoxin	unknown	unknown	gnl\|CDD\|365862
CP020664.1\|AVQ72912.1\|3535312_3536368_+\|Fe(3+)-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270260
CP020664.1\|AVQ72911.1\|3534489_3534867_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ72902.1\|3526120_3526354_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ72908.1\|3529106_3529400_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225291
CP020664.1\|AVQ72906.1\|3528306_3528504_-\|addiction-module-toxin,-HicA-family	unknown	unknown	gnl\|CDD\|377942
CP020664.1\|AVQ72905.1\|3527977_3528271_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225291
CP020664.1\|AVQ72896.1\|3521384_3521480_+\|plasmid-maintenance-system-killer-protein	unknown	unknown	unknown
CP020664.1\|AVQ72909.1\|3529392_3529761_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375906
CP020664.1\|AVQ72903.1\|3526341_3526752_+\|PIN-domain-nuclease	unknown	unknown	gnl\|CDD\|350220
CP020664.1\|AVQ72895.1\|3520551_3521397_+\|flagellar-assembly-protein-H	unknown	unknown	gnl\|CDD\|371375
CP020664.1\|AVQ72899.1\|3523440_3524619_-\|succinyldiaminopimelate-aminotransferase	unknown	unknown	gnl\|CDD\|180947
CP020664.1\|AVQ72910.1\|3530096_3534488_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|214361
CP020664.1\|AVQ72898.1\|3523271_3523460_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP020664.1\|AVQ72914.1\|3537712_3540349_+\|DNA-topoisomerase-I	gnl\|CDD\|236048	PRK07561, PRK07561, DNA topoisomerase I subunit omega; Validated.	0
CP020664.1\|AVQ72901.1\|3525043_3525922_-\|peptide-ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.40413e-86
CP020664.1\|AVQ72913.1\|3536668_3537283_-\|SAM-dependent-methyltransferase	gnl\|CDD\|253548	pfam06080, DUF938, Protein of unknown function (DUF938). This family consists of several hypothetical proteins from both prokaryotes and eukaryotes. The function of this family is unknown.	1.7237e-87
CP020664.1\|AVQ72904.1\|3526779_3527859_+\|TIGR00303-family-protein	gnl\|CDD\|235300	PRK04447, PRK04447, hypothetical protein; Provisional.	1.82101e-177
CP020664.1\|AVQ72907.1\|3528504_3528750_-\|hypothetical-protein	gnl\|CDD\|312506	pfam08972, DUF1902, Domain of unknown function (DUF1902). Members of this family of prokaryotic proteins adopt a fold consisting of one alpha-helix and four beta-strands. Their function has not, as yet, been elucidated.	2.23231e-23
CP020664.1\|AVQ72900.1\|3524635_3524998_-\|thiol-reductase-thioredoxin	gnl\|CDD\|365862	pfam00085, Thioredoxin, Thioredoxin. Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond. Some members with only the active site are not separated from the noise.	8.87004e-32
CP020664.1\|AVQ72912.1\|3535312_3536368_+\|Fe(3+)-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270260	cd13542, PBP2_FutA1_ilke, Substrate binding domain of ferric iron-binding protein, a member of the type 2 periplasmic binding fold superfamily. FutA1 is the periplasmic component of an ABC-type iron transporter and serves as the primary receptor in Synerchosystis species. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria and is critical for survival of these pathogens within the host. After binding iron with high affinity, FutA1 interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The iron- and thiamine-binding proteins belong to the PBPI2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.16383e-151
CP020664.1\|AVQ72908.1\|3529106_3529400_+\|hypothetical-protein	gnl\|CDD\|225291	COG2442, COG2442, Uncharacterized conserved protein [Function unknown].	2.73197e-16
CP020664.1\|AVQ72906.1\|3528306_3528504_-\|addiction-module-toxin,-HicA-family	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	6.93262e-08
CP020664.1\|AVQ72905.1\|3527977_3528271_+\|hypothetical-protein	gnl\|CDD\|225291	COG2442, COG2442, Uncharacterized conserved protein [Function unknown].	3.02303e-15
CP020664.1\|AVQ72909.1\|3529392_3529761_+\|hypothetical-protein	gnl\|CDD\|375906	pfam18480, DUF5615, Domain of unknown function (DUF5615). This is a domain of unknown function found in potential toxin-antitoxin system component.	6.62344e-07
CP020664.1\|AVQ72903.1\|3526341_3526752_+\|PIN-domain-nuclease	gnl\|CDD\|350220	cd09872, PIN_Sll0205-like, VapC-like PIN domain of Sll0205 protein and homologs. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of the Synechocystis sp. (strain PCC 6803) Sll0205 protein and other uncharacterized homologs are included in this subfamily. They are similar to the PIN domains of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	4.26555e-39
CP020664.1\|AVQ72895.1\|3520551_3521397_+\|flagellar-assembly-protein-H	gnl\|CDD\|371375	pfam11103, DUF2887, Protein of unknown function (DUF2887). This bacterial family of proteins has no known function. These proteins may be distantly related to the PD(D/E)XK superfamily.	8.49812e-99
CP020664.1\|AVQ72899.1\|3523440_3524619_-\|succinyldiaminopimelate-aminotransferase	gnl\|CDD\|180947	PRK07366, PRK07366, LL-diaminopimelate aminotransferase.	0
CP020664.1\|AVQ72897.1\|3522411_3523206_+\|flagellar-assembly-protein-H	gnl\|CDD\|227751	COG5464, COG5464, Uncharacterized conserved protein [Function unknown].	1.22685e-31
CP020664.1\|AVQ72910.1\|3530096_3534488_+\|hypothetical-protein	gnl\|CDD\|214361	CHL00095, clpC, Clp protease ATP binding subunit.	4.98029e-43

>CP020664.1|AVQ72904.1|3526779_3527859_+|TIGR00303-family-protein
MIKIYTEIEGGQNWLERHQKSSPIFALVLGFTETGLIPGISTAGATPEDRKYTAIADAEFIVKGVSPHPRYPLPPLTVGASPAYITRAVVEKLAIPVRVFNAGLPLPPAVDYIELGGQPACCLSTGRALDFDIVKHLFAQGLTWGEKLARESSYLIIGECVVGGTTTALAILTGLGYRANGKVNSSHPQCNHAQKWAIVEQGLARKEIFDPFEVIAALGDPQQIFVAGMAIAASGQGGVLLAGGTQMLAVSALIKALVAKYAYPVNWENIIVGTTRWVAEDKTGDTVGLARMIGKVPLLATQLNFSASKYPVLQAYEQGFVKEGVGAGGCAIAAYLYQNWTNQDLLKAIENLIGFQLNC
>CP020664.1|AVQ72903.1|3526341_3526752_+|PIN-domain-nuclease
MSEVIVLDTHIWLWLINGNFDRFPEHWLEKFELAESLGVSPISCYEIALANQRGRLELSYPLQEWIQQALTVAKIDIFSITPEIAIRAVNLSPIHKDPFDRIIMATALAYGAKLASIDNLFSKYVEIKDHLMERGK
>CP020664.1|AVQ72902.1|3526120_3526354_+|hypothetical-protein
MTVKELIQTAIDNLPEEQLDELYQLIKNFTASKNNLLEEKPSLFKRHFPVENMVGKAKILGDMVSPIVDEEDWECLK
>CP020664.1|AVQ72901.1|3525043_3525922_-|peptide-ABC-transporter-permease
MSPLSSAIIDTWRRFYRDPLATIGAIALIIIILAVLFGPIFYRVPIDTIDFSQTTAPPSLKHLFGTNDLGQDQLARILVGGRISLAVGIAAMIVAIILGTAIGAISGFYGGAIDGLLMRLTDLFLSLPQLPLLLLIVYLFRDSIKKIAGPETGIFILVVLVIGGLNWMSVARLVRGNFLKLREMEFVSAAIALGATPFRLIWVHLLPNVLGMIIVAATLAVGNAIITESTLSFLGLGFPPDVPTWGQMLFKAKDYLTTAPHLVIFPALAIVITVLSINFIGDGLRDVFDPHV
>CP020664.1|AVQ72900.1|3524635_3524998_-|thiol-reductase-thioredoxin
MMISNDGEEINTVSSVTVISDQKFDQEVFEVEKPVLVYFWASWCGPCRLVSPSIDWVANTYGERLKVVKLEVDPNPNSVAKCDVKGVPALRIFKDNEIIATHEGAIGKQQLQSFIDTYVS
>CP020664.1|AVQ72899.1|3523440_3524619_-|succinyldiaminopimelate-aminotransferase
MNNLTLAHRLQALQSNVFADMDRAKAASREAGNIIIDLSLGSSDLGAAPHVVDAIERSLHDPHTHGYLLHNGTRDFRITAANWYSDRFGVPIDPETEVLPLIGSQEGTAHLPLALLNPGDFALLLDPGYPSHLGGVALAGGQIYGMPILAKNDFLPVLEDIPEAVLAQSKLMVLSYPHNPTTAIAPLAFFQKAVDFCRQHNLVLIHDFPYLDIFFAGTSPPPSILQADRAKTNSIEFFTFSKSYNMGGFRIGFAIGNPQLIMALRQIKAMVDFNQYLGILNGAIAALTGNQDSVKETVAIFQKRRDVFINALNRIGWPVATPAATMYVWAKIPPSWPGNSVDFCRQLVAQTGVAVSPGSGFGKGGEGYVRFALVHDPDILEAAVEKIGAFLG
>CP020664.1|AVQ72898.1|3523271_3523460_-|hypothetical-protein
MGLFWDKTDILSSGYAAIDNFRLVAADIPGDIGNVSTPKLSSIIGLGILGSGLVVCRLAKRR
>CP020664.1|AVQ72897.1|3522411_3523206_+|flagellar-assembly-protein-H
MFDNICKFIAENFSDDLATWLLGSPLPLTVLDPTELQLDPIRADSLIFLQSEELILHTEFQTDPDAKIPFRMLDYRIRVYRRHPQKQMRQVVIYLRRSDSPLVQENTFRLGETFHSFQVIRLWEENTPQFFHHPGLLPFAILSNTDDPEQVLSLVSRSLETIPEKQVQSNLAAATSILAGLVLNRETIKKILRSDIMRESVIYQDILEEGEEKGLKKGLQAGKEEKARQIALKMLSAGVPISEIARFTDLSPDVIEELQRQQHN
>CP020664.1|AVQ72896.1|3521384_3521480_+|plasmid-maintenance-system-killer-protein
MVNLIGLSLEQIAQALDLEIEQVPEVNEGQN
>CP020664.1|AVQ72895.1|3520551_3521397_+|flagellar-assembly-protein-H
MKTDSIFYRLFETFPESFFDLLNLPPETVNHYQFSSLEVKQLAFRLDGVFLPDNLNDPIYFVEVQFQKDERFYSRFFSEIFLYFHQSEISNNWQGVIIYPHREIENSPKSRYQEFFESGRVNCYYLNQLEEGDSLGVKVLQLIVESEQNTLGQGKELIQQVRQQFQESLKREDILELIETILIYKLPKLNRKEIEKMFSLSDLRETKVYQEALEEGREEGREEGELSAKKSLILRQLNLKLGSIPLKLEQKIKQLNPNQLDNLALALLGFSDLEDLQQWLT
>CP020664.1|AVQ72905.1|3527977_3528271_+|hypothetical-protein
MLTEINIGTFIKSDPKIHGGCPIIAGTAVTVRRIVIWYKLGYSLEEIADEIPHLSLAQVYDALTYYHTNKETIEAEIIAEAAEADRIEALHYSSSYE
>CP020664.1|AVQ72906.1|3528306_3528504_-|addiction-module-toxin,-HicA-family
MATSLTPALKKLLSAAGCYFERQGKGDHEIWYSPLTERRFVVDNTIKSRHTANAVLKQAGLSKSF
>CP020664.1|AVQ72907.1|3528504_3528750_-|hypothetical-protein
MNQKPYQVEAFWDREAQVWVAESEDIPGLVTEADTIEALTAKLRQMIPELLQLNHLITLEPQAPITFELISHRQESIECAV
>CP020664.1|AVQ72908.1|3529106_3529400_+|hypothetical-protein
MLTEINIGTFIKSDPKIHGGCPIIAGTAVTVRRIVIWYKLGYSPEEIADEIPHLSLAQVYAALTYYHTNKETIEAEIIAEAAEADRIEALHYSSSYE
>CP020664.1|AVQ72909.1|3529392_3529761_+|hypothetical-protein
MSRISLYMDEDSTLRSLAFILKSRGVDVITALEANRLGYSDEEQLIWATSQGCSLYSSNVRDFYYLHTLFLQQKRNHAGIILVQQQRYSMGEIMRGILQLIATKSAEEMIDQVEFLSAWITR
>CP020664.1|AVQ72910.1|3530096_3534488_+|hypothetical-protein
MFERFTEKAIKVIMLAQEEARRLGHNFVGAEFIFLGLIGEATGIASQVLRQQGITLKNARIEVEKILGRGSGISPEMNPVDIPFTESAKLVLNSALSFADKLGSESIDTEHLLIGIFQQRESTAIILQNLQVNLKDLTVSLTQYFQQQPSNQLPQTVYVLLYNVGADDEGIHTISTGNKDTILIFETQEDAATFARRLGEQNFPVPSVEAIEAEAILLFCKNSGDDWEFVAQGTNRIPPSENQTINQQNTFVDQSSPGVTLDIEIPNQQDYLNFLMETLQKISENPNPQVIYPFWAQNLDKLDYNLAQILDSWARERLTQATPEQAYFIAIVIFYFSALIQQFPLGDIAVNQEIAITGYEIALTIFTFDAFPQNWAETQNNLAIAYRDRIRGEKAENLERAIAACQEALKVRTFDAFPQDWAATQNNLAIAYRDRIRGDKADNLERAITAYQEALKVFTFDAFPQDWAMTQNNLAIAYSDRIRGEKAENLERAIAAYQEALKVYTFEAFPQQWAMTQNNLAIAYSDRIRGEKAENLERAIAAYQEALKVRTFDAFPQDWAMTQNNLAAAYRHRIRGEKAENLERAIAAYQEALKVRTFDAFPQDWATTQNNLAAAYSDRIRGEKADNLERAIIVYQEALKVRTFEAFPQQWALIQNNLALAYSNRIRGEKAENLERAIAACQEALKVRTFDAFPQQWALIQNNLALAYSNRIRGEKAENLERAIAACQEALKVRTFDAFPQDWAATQNNLAIAYRDRIRGDKADNLERAIIVYQEALKVFTFDAFPQDWAATQNNLAAAYRDRIRGEKAENLERAIAACQEALKVYTFKAFPQQWALIQNNLALAYSNRIRGEKAENLERAITSYQNALTIRTKESDPFNCLQTARNLGSLHYSEEQWQPATEAYHIAIEAVENARLEALNPHSRQEVLSNAIGVFHRIVQAYLNLNQPEKALEYIERSKGRNLVELITQKNLQPQGVSQEIIAQLNELKQRVVNEQIRLQHQSINQNLMGRDNLTPYVQDHSYLKEYQQDLDNFIAREIKDTLFSLTEKVEPIPFTEIQALTDAETCLLQWYITGEKILAFVVSAEGEVKVWQSSEDDKNQLFDTFNNYLQLYYSGNGKQEWRNQLSNLLQTFADILHINDILALIPDTCQRLIIIPHWFLHILPLHALPVDPPQPPLKSGESATGRSELQDLFPKGVQYAPSCQILQKISQTFHHSDFNKLFAIQNPTKDLFYTDLEVNILSTFFTEPQVIAKDNATKNAVLPHLKSSDNHCYHFSCHGSFNPANPLESALFLANKKSLTLGEIFELRLNKCRLVTLSACETGLIDLNSISDEYIGLPSGFLFAGSPSVVSSLWTVNDLSTSFLMIKLYEILFDENQQVSVPVALKTAQNWLQNLTVQEYFNQLDSCLKIVKSMQQKLTSKEFNRLMDMIEDEQIRIKGFELNYKLFNNPFYWAAFTASGI
>CP020664.1|AVQ72911.1|3534489_3534867_-|hypothetical-protein
MDIESTKVTAEEIAQFRAELAEDSNALGDIDLIEQCDGDLKYAAMRLARRSNIDTVRADEDNFWQQAITQARQLICHDRVKDDLAPNILGGLVGLLATSGNPVLVVVATPLAIHVFRETLDNFCD
>CP020664.1|AVQ72912.1|3535312_3536368_+|Fe(3+)-ABC-transporter-substrate-binding-protein
MNDKITRRVFLGAGTATLALAVGQLGKINEVSAQTNQLNLYSSRHYNTDRRLYDNFTRQTGIKINLVEGEADPLIERIKSEGRNSPADILLTVDAGRLWRADQQGIFAPVNSRILTQRIPANLRHPKGHWFGFSKRLRVIMYNKDRVNPREIDSYADLTNPKWKGKVVTRSSSNIYSQSFTAWLIDIQGEAAAEKWCRGLVANFARSPQGNDKAQIEAVAAGIADLALANTYYLAGYAEEKDPAKRAIYDQVGVIFPDQTGRGAHVNISGGGLIKTAPNRESAIKFLEYLSSNEAQNFFAKGNQEYPVVRGVALDPVLAKLGRGKEDTVSVANYGPNLAKAVQVMNRAGWK
>CP020664.1|AVQ72913.1|3536668_3537283_-|SAM-dependent-methyltransferase
MSDLRQYAPATERNRQPILEVLSQFLPKTGNILEISSGTGEHAVFFAPRLAPCRWIPSDCNPLALDSIRSWCDYYPSSNLDRPLFIDVHQSVWAVEKENIVINAIVNINMIHIAPWSACLALMAGASRILSSGEILYLYGPYKRQGKHTSPSNESFDLSLRSQNSAWGVRNLEDVVQAASDRGLQLLEVIPMPANNLSVLFALT
>CP020664.1|AVQ72914.1|3537712_3540349_+|DNA-topoisomerase-I
MSTLVIVESPTKARTISNYLPSGYRVQASMGHIRDLPASAEEIPPAQKDKSWANLGVDVENDFDPLYVVPKTKSKIVKELKEALKGASELILATDEDREGESISWHLLQVLNPKIPTKRMVFHEITKEAIQTALKNCRSIDENLVHAQETRRILDRLYGYTLSPLLWKKISKGLSAGRVQSVAVRLLVQRERERRAFKTANYWDLKATLEKDKNQFDSKLVTLNGQKVANGSDFDADTGRLLPGRQVTLLDQATAAALKERIQDKIWRVSHTEEKPTTRKPSPPFTTSTLQQEANRKLGISARDTMRIAQNLYEQGYITYMRTDSVHLSDQAITAARNCVEQMYGKNYLSPQPRQYTTKSKGAQEAHEAIRPAGSSFRLPRETGLSGLEFALYDLIWKRTVASQMADARITQIAVNIQVEDAGFRSSGKRIDFPGFFRAYVEGSDDPEAAIDDQEIILPPLSVGDTPNCRKLEAISHDTQPPARYSEASLVKTLESEGIGRPSTYATILGTIIDRGYAQMRNKTLIPTFTAFAVVSLLENHFPDLVDPKFTSKMEETLDDIATGSAQWLPYLDRFYRGEKGLESQVKERESQINSSTAKSVILEDLQATIKIGKYGPYLEVSRDDQILTASIPADLTPADLNPEQVETLLRQKTAGPDKIGLDPDTGEPIYLLVGSYGPYVQLGDVSDDNPKPKRASLPKGVKPDDITLEQAVGLLALPRLLGTDPLTGGKIKASLGRFGPYIVREEGKEKEYRSLKAGDDILTITLDRALALLAEPKKARSTRGSGKPPLKELGKHPDDGELVALYEGPYGVYIKHAKTNAKIPEGETAETLTLEQALSALAAKATTAKKTTTKKTTSSTTKKTTSPGSKTSKSKKV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP020664_18

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020664_18

4246576-4246669

TypeV

Consensus_repeat	Method
GAAATTGATTTTGTCCGATTTTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020664_18

>merge|CP020664|18|4246576-4246669|CRISPRCasFinder
GAAATTGATTTTGTCCGATTTTATTGTCCAGGATCTGTAGGGTTGATTCATGAATCAACCCTACCCCACCAGAAATTGATTTTGTCCGATTTTA

>CP020664|18|16|4246576-4246669|CRISPRCasFinder
GAAATTGATTTTGTCCGATTTTA	TTGTCCAGGATCTGTAGGGTTGATTCATGAATCAACCCTACCCCACCA
GAAATTGATTTTGTCCGATTTTA

Protein	Signature genes	Signature genes Name	Protein_function
CP020664.1\|AVQ73505.1\|4244214_4246398_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131644
CP020664.1\|AVQ73509.1\|4249899_4250334_-\|bacterioferritin	unknown	unknown	gnl\|CDD\|225104
CP020664.1\|AVQ73513.1\|4254075_4254216_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379471
CP020664.1\|AVQ74405.1\|4254232_4254583_-\|transposase	unknown	unknown	unknown
CP020664.1\|AVQ73503.1\|4241057_4242296_+\|DNA-(cytosine-5-)-methyltransferase	unknown	unknown	gnl\|CDD\|273211
CP020664.1\|AVQ73510.1\|4250562_4251423_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276809
CP020664.1\|AVQ73507.1\|4247168_4248782_-\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380492
CP020664.1\|AVQ73499.1\|4236590_4237442_+\|phosphorybosylanthranilate-isomerase	unknown	unknown	gnl\|CDD\|223511
CP020664.1\|AVQ73497.1\|4233615_4235055_-\|ATP-dependent-RNA-helicase	unknown	unknown	gnl\|CDD\|223587
CP020664.1\|AVQ73511.1\|4251900_4253586_-\|dihydroxy-acid-dehydratase	unknown	unknown	gnl\|CDD\|234861
CP020664.1\|AVQ73508.1\|4248944_4249865_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|272930
CP020664.1\|AVQ73496.1\|4230918_4231272_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240401
CP020664.1\|AVQ73515.1\|4256024_4256273_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ73512.1\|4253731_4253938_+\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ73498.1\|4235096_4236410_-\|ribosomal-protein-S12-methylthiotransferase-RimO	unknown	unknown	gnl\|CDD\|273453
CP020664.1\|AVQ73501.1\|4238715_4239909_+\|methyltransferase	unknown	unknown	gnl\|CDD\|334588
CP020664.1\|AVQ73500.1\|4237619_4238606_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240599
CP020664.1\|AVQ73504.1\|4243003_4243225_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ73514.1\|4255615_4255858_-\|hypothetical-protein	unknown	unknown	unknown
CP020664.1\|AVQ73502.1\|4240229_4241009_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP020664.1\|AVQ73505.1\|4244214_4246398_+\|hypothetical-protein	gnl\|CDD\|131644	TIGR02595, conserved_hypothetical_protein, PEP-CTERM protein-sorting domain. This model describes a 25-residue domain that includes a near-invariant Pro-Glu-Pro (PEP) motif, a thirteen residue strongly hydrophobic sequence likely to span the membrane, and a five-residue strongly basic motif that often contains four Arg residues. In nearly every case, this motif is found within nine residues, and usually within five residues, of the extreme C-terminus of the protein. Proteins with this motif typically have signal sequences at the N-terminus. This region appears many times per genome or not at all, and co-occurs in genomes with a proposed protein-sorting integral membrane protein we designate exosortase (see TIGR02602). PEP-CTERM proteins frequently are poorly conserved, Ser/Thr-rich proteins and may become extensively modified proteinaceous constituents of extracellular material in bacterial biofilms. [Cell envelope, Surface structures].	3.81485e-05
CP020664.1\|AVQ73509.1\|4249899_4250334_-\|bacterioferritin	gnl\|CDD\|225104	COG2193, Bfr, Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism].	2.24956e-32
CP020664.1\|AVQ73513.1\|4254075_4254216_+\|hypothetical-protein	gnl\|CDD\|379471	pfam14104, DUF4277, Domain of unknown function (DUF4277). This presumed domain is functionally uncharacterized. This domain family is found in bacteria and archaea, and is approximately 110 amino acids in length. There is a conserved NGLGF sequence motif.	1.09237e-12
CP020664.1\|AVQ73503.1\|4241057_4242296_+\|DNA-(cytosine-5-)-methyltransferase	gnl\|CDD\|273211	TIGR00675, Modification_methylase, DNA-methyltransferase (dcm). All proteins in this family for which functions are known are DNA-cytosine methyltransferases. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	5.48771e-97
CP020664.1\|AVQ73510.1\|4250562_4251423_-\|hypothetical-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.61709e-18
CP020664.1\|AVQ73507.1\|4247168_4248782_-\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380492	cd06268, PBP1_ABC_transporter_LIVBP-like, periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.	3.03043e-54
CP020664.1\|AVQ73499.1\|4236590_4237442_+\|phosphorybosylanthranilate-isomerase	gnl\|CDD\|223511	COG0434, SgcQ, Predicted TIM-barrel enzyme [General function prediction only].	2.40995e-132
CP020664.1\|AVQ73497.1\|4233615_4235055_-\|ATP-dependent-RNA-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	6.78276e-160
CP020664.1\|AVQ73511.1\|4251900_4253586_-\|dihydroxy-acid-dehydratase	gnl\|CDD\|234861	PRK00911, PRK00911, dihydroxy-acid dehydratase; Provisional.	0
CP020664.1\|AVQ73508.1\|4248944_4249865_-\|hypothetical-protein	gnl\|CDD\|272930	TIGR00145, Uncharacterized_protein_slr0964, FTR1 family protein. A characterized member from yeast acts as oxidase-coupled high affinity iron transporter. Note that the apparent member from E. coli K12-MG1655 has a frameshift by homology with member sequences from other species. [Unknown function, General].	6.17636e-60
CP020664.1\|AVQ73496.1\|4230918_4231272_+\|hypothetical-protein	gnl\|CDD\|240401	PTZ00397, PTZ00397, macrophage migration inhibition factor-like protein; Provisional.	6.9477e-24
CP020664.1\|AVQ73498.1\|4235096_4236410_-\|ribosomal-protein-S12-methylthiotransferase-RimO	gnl\|CDD\|273453	TIGR01125, Ribosomal_protein_S12_methylthiotransferase_RimO, ribosomal protein S12 methylthiotransferase RimO. Members of this protein are the methylthiotransferase RimO, which modifies a conserved Asp residue in ribosomal protein S12. This clade of radical SAM family proteins is closely related to the tRNA modification bifunctional enzyme MiaB (see TIGR01574), and it catalyzes the same two types of reactions: a radical-mechanism sulfur insertion, and a methylation of the inserted sulfur. This clade spans alpha and gamma proteobacteria, cyano bacteria, Deinococcus, Porphyromonas, Aquifex, Helicobacter, Campylobacter, Thermotoga, Chlamydia, Streptococcus coelicolor and Clostridium, but does not include most other gram positive bacteria, archaea or eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification].	0
CP020664.1\|AVQ73501.1\|4238715_4239909_+\|methyltransferase	gnl\|CDD\|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	1.16491e-07
CP020664.1\|AVQ73500.1\|4237619_4238606_+\|hypothetical-protein	gnl\|CDD\|240599	cd12916, VKOR_1, Vitamin K epoxide reductase family in bacteria and plants. This family includes vitamin K epoxide reductase (VKOR) present in bacteria and plant. VKOR (also named VKORC1) is an integral membrane protein that catalyzes the reduction of vitamin K 2,3-epoxide and vitamin K to vitamin K hydroquinone, an essential co-factor subsequently used in the gamma-carboxylation of glutamic acid residues in blood coagulation enzymes. All homologs of VKOR contain an active site CXXC motif, which is switched between reduced and disulfide-bonded states during the reaction cycle. In some plant and bacterial homologs, the VKOR domain is fused with domains of the thioredoxin family of oxidoreductases which may function as redox partners in initiating the reduction cascade.	4.11085e-50

>CP020664.1|AVQ73505.1|4244214_4246398_+|hypothetical-protein
MNSQNTVRLGWSVMIGVITPLIVPNLAEGANLRTPMIKEGYLSFRHSGPTFNGEERTGWTDVRHPALDGTVDNVRGYDWSDNLVRVLTHNVNAPGGNSNVNPDLRRQDFDVANAIYAQAGITILQENNITIPGNDIVTSMIMPPGSPVGGSTVEPSLSMLFGKNRSANTDTVNQYYVDDIPVAEGYTLPPIYASRGGFAFGGNNTNPLPPGTPNFNNGFAIADTSRSLPNGGSSTFAHELGHFLMDDNRFTSGDPFHSRLADDLMNANPDDPNPTAYKIQAEMFGLREPGQRIGNIGTKSHFGENVTNLAGGAAITQIEALHRSPFVKRDDNGFTHGDRADFDWVEDNIPLELATQTGDNHSGIDFLTWEIANIAPSQHLWEHPSASTLNIEHQHDNWLTGDRPELTLGRFNGNTFQIVDVISQIARYADMDVGASGNWSPRESALDYIIEFSSDSINWVRGTLNSVFEDGWTLASKAEDYVARWFSDVQAKFVRIAAQPLGGNHDGNTQIDAIIAGTAKDFGDAPDSYKTLLASDGPRYDEGNLQRLGSQWDSEIDGQPTILADGDDKSILGGFPTPVDDEDGVVFGDSWVDVTFNISRPDPNPYQLRAWWDTNYNGVFDHTSELYIDDLLTLAPGIFTKRYNLGFNPKADGLYSRFRLTWDPLDLDVKPFGEYYSKADCNTTDAAAGNCVSHGEVEDYVHVPEPSSIFGLLAFTGLGLMGLRKKR
>CP020664.1|AVQ73504.1|4243003_4243225_-|hypothetical-protein
MNSYQTYLTIDHSQKIILSNLPFKAGTKLAINIQVVEDEKTEADFEALLDKTQAIWTKGDGLEYQQKIREEWI
>CP020664.1|AVQ73503.1|4241057_4242296_+|DNA-(cytosine-5-)-methyltransferase
MTQVNLQKAANILGVTTAEILTWQKKKLIKGQKINQVDWLFDLEQLTNLKNNQSPRELKILQTVEPTNYTVIELFAGCGGMALGLENAGLKTQLLVEINQDCVNTLRLNRPQWNVINQDIKKIKFSNFRDKIDIVAGGFPCQPFSYAGLGKGLEDLRGSLFFEFARCLQEVQPKIAIAENVRGLLSNKKGETLQLMLEALQEIGYYAAYQVLSAQFLDVPQKRERLIIIATRQDLNIKPIFPQYKNYTISLKKALENCPSSPGVEYKERKKEIMSLVPAGGNWRNLPMDIQKEYMKNSLKNHGGRTGYAKRLSWDEPALTITCSPAQTQTERCHPQETRPLTVREYARVQSFPDDWQFTGNLTSQYRQIGNAVPVNMAYHLGGCLINMLQGDYIGETQPKTEQLSIPGLEVN
>CP020664.1|AVQ73502.1|4240229_4241009_+|hypothetical-protein
MSYLYSYRHNLTQLLEEINLQKPSIKIPTFVTHDLVDTYQICRLIDDFIFEYFQENRKTDTDIADNRDQKIDDALDEFQSKVVEKILKEKQDFKNISLKKKKGFKNIFEFAQCENLYLSNKYVNLISESLGHTLEEIASISSQVFVPEKILNFKIKGVDLVVFNQGIIKYTQLKTKKDTLTGSQSDRSINELKIHPNSVFAAALDMGNSWTISKTKAKENNIELLAGQAFWSMLDLDYETILNKLKMTVRKIEKKLYQV
>CP020664.1|AVQ73501.1|4238715_4239909_+|methyltransferase
MPDFDQPIPQEKLDIIEKTRANLFVWRGQFSPQLIETILSFYCPSNSVILDPFVGSGTVLLEASYLSLEAYGFEINPAAYIMSRTYEFINDSQKKEVLKNLRNILDQEFPLRIFEVSDQVENLVDKLQNTRNMLPDRSKVLFDALVIILDVCNNKITQEFIQKKFLHLSNIITKLPYSQKPIRVGLSDARSLPLKNNQIDFVVTSPPYINVFNYHQNYRQSAEILGWDLLKIAKSEIGSNRANRSNRFYTVVQYCLDMGDILKELARVSKQQARIVLIVGQESNVLGVPFYNADIIEKIGIKAKLFQKVLRQKRKFKNKFGKVIIEDIINFINLNNQVSQEVIEQISREVAFEVLESSRLFVSSENQLCLESAIAKVNNIQRTPILDKRLYIDPVNI
>CP020664.1|AVQ73500.1|4237619_4238606_+|hypothetical-protein
MRRRSVPWIHRYSRPLIGGVSIVGAILTGYLTITKLTGGAAACTAGASDGAGCSGVLNSPYATVFRLPLSLFGFLAYIAMAVFALSPLFINGETQKNLRKSLENNTWLLLLAGATAMAVFSGYLMYVLATELKELCPYCITSALFALTLLILTIVGREWEGLGQIILPMVVVAMITFVGTLAVYAGVNSPTVAGGKEEITRPMTAAKPPYGWEVTTVSGKAEIALAKHLKAIGAKEYGAFWCPHCYDQKQLFGKEAGEILKKEGVYIECDPQGVNGNPQACRDAGIKGFPTWIIKGQEYSGTQRLEKLAEVSGYTGPMNFKYTVPGRK
>CP020664.1|AVQ73499.1|4236590_4237442_+|phosphorybosylanthranilate-isomerase
MNLIATFKTKNPIIGVVHLAPLPTSPRWGGSLKTVIERAEQEATALAAGGVDGLIIENFFDAPFTKQQVDPAVVSAMTLIVDRIKNLVVLPIGLNVLRNDAHSALAIATCVNAQFIRVNVLTGVMATDQGIIEGQAHELLRYRRELGSEVKILADVLVKHARPLGTPNLTTAVQDTIERGLADGVILSGWATGSPPSFEDLELAVAAAKGTPVFIGSGADLDNIGQLLPAADGVIVASSLKRHGKITEPVDPIRVSQFVETARQINDQKAKINNSLPSLPLST
>CP020664.1|AVQ73498.1|4235096_4236410_-|ribosomal-protein-S12-methylthiotransferase-RimO
MGNKPTIAISHLGCEKNRIDSEHMLGLLAKAGYPVDNDEELADYVIVNTCSFIQAAREESVRTLVELAEANKKIIISGCMAQHFQDELLTELPEAVAIVGTGDYQKIVEIVERVETGERVKEVSTDPTFIADENLPRYRTTTEGVAYLRVAEGCDYRCAFCIIPHLRGDQRSRSIESIVAEARQLASQGVQELILISQITTNYGLDLYGEPKLAELLRALGEVDIPWIRVHYAYPTGLTPKVIEAIRETPNVLPYLDLPLQHSHPHILRAMNRPWQGRVNDGIIERIKQAIPNAVLRTTFIVGFPGETEEHFSHLLEFVKRHEFDHVGVFTFSAEEGTAAFDLPNPVPQAIMEERRERLMLTQQPISERKNQAYIGHTVDVLIEQENPETGELIGRSARFSPEVDGLVYVTGEAILGAIVQVRITSADTYDLYGEIV
>CP020664.1|AVQ73497.1|4233615_4235055_-|ATP-dependent-RNA-helicase
MTTGFNNLGLSDSRLQHLETLGFTTPTEIQTKAIPLLLEGHDMVGMSQTGTGKTAAYSLPLLERMDTKNPNVQALILTPTRELAQQVASAIKDFSDDRRLFILTVCGGQSMERQIRSLEKGVQIVVGTPGRVIDLLDRKKLHLESLNWVVLDEADEMLSMGFIDDVKKILQASPSTRQTACFSATMPREIRDLIANFLKSPVSVTVSQPQAAPAKIEQKIYLIPRGWTKLKVLQPLLEIEPLESAIIFVRTKQTAAELTSKLQEAGQTVDEYHGNLSQVQRERLVQRFREGKIKLVVATDIAARGLDVENLSHVINYDLPDNAETYIHRIGRTGRAGKTGTAISLVEPIDRRLLRQIEQRLRQRLESSPIPSRTEVEAKRLAKLQNQLKEALSGERMASFLPLVRDLSEEYDPQAIAAAALQMIYDQNCPQWMKTDWEVPAAASSKPVINKTPRSGGNKYPSKSNNRPSLDKKIVFQER
>CP020664.1|AVQ73496.1|4230918_4231272_+|hypothetical-protein
MPLIKIQTSVTSLDDETVNQLLQSLSAKLAKHLGKPESYVMTALESGIKMTFAGTFEPVCYVEIKSVGSISAAQTKSMSSDFCQEIEAYLGIPKNRIYLEFAEAKGDLWGWNGTTFG
>CP020664.1|AVQ73507.1|4247168_4248782_-|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein
MTTWQCDGIPKDGKTYPQAIAGGHEPCENTTPDCPICGLPREAMDPVTTTVKTTVVVSPGGTTKVGRKSNWLLPFALIITALTAGLGGWSLLQMLIPKPDTSQVTPEETPDKQPKATFVSNTAKNPDLFSQGEKILLNSTPNKEKGAAAFKKEDWANAIAAYQLAATPQANDPEGKIYYNNAKARQKGNQNTIAVVVPIANDPNSAKEILRGVARYQEEFNNSNPGNPLEIVIANDGGGLQSKAIADDLIQSGQVLAVMGHGIDPFSQKAIESYEKEGLAILSPLTTSVSQTGNATLKTIPLKDKSQEVLGSYLEAVAKTLANYASQQENSPSVVLFYNSDSPYSQKLKDSFAKAIKEPGGKIVKAIDTTKANFNAKTAIDQARQAGAKVVFLALSKDGDRIDQAVAIAQESSGMLLLGGNELYTPDILIQGADSIDGLVLAVPWSFQATDPFAKDALKSWRGRVSWRTATAYDSMKVLGEAIAKSSDRATVVETLNRGITLQGSTTDFKIFNQVPLVRANRGNEGPKGSQYQFDPI
>CP020664.1|AVQ73508.1|4248944_4249865_-|hypothetical-protein
MNLSSALPTFIITLREGFEAALVVGIVLACLQKSGRSQLNSWVYRGIGAGVVASVLVGILLGGILLQVDASPSPFVPMLKELLAATFGLIAVLMLSWMLIWMTQQAKSLKSEVESAVKAGLKAKNGAGKAIFLLVFIAVLREGFETVLFILAQFQKDWQIQTFGAIAGLSVATLLGTLLFAGGVKINIRLFFQIMGTFLLLIVAGLLIGVLKHIDAGISLLSEIDPFYRNFCPSLPSSCLLGFQVWDGSQILSDRTFPGLLLKSLFGYRQNLYISQIVAYILFLLLIGGLYFQSLRQRPQTVTSDQ
>CP020664.1|AVQ73509.1|4249899_4250334_-|bacterioferritin
MRELDRDKTIEQLNEIMEFELAGVVRYTHYSLMVTGPHRIPIVQFFQTQATESLTHAQQVGEILTGLEGHPSLKIAPIEESYEHNIKAILSESLNHEKKSLDLYKALLETVEDASIYLEEFARGMIGQEELHNLEIRKMLRDFA
>CP020664.1|AVQ73510.1|4250562_4251423_-|hypothetical-protein
MTYLLTVYRALECRPDTYRDWYDQGNILKERMDYFGALISYEKALEYYPDDYWAWYKRGMILEDLGMYEEAAESYANAAQVKDDNYWAWYDQGCVYLQELKDYQKAIACFQRALSHSPGDYWAAYRQGEAYRLLKNYERAITFYDLALGARPRDYWAWYRRGDAFRDWGNPQEALFNYRTALDIRPQDYWSWYQQGVILQELQRLPEAIACYEELLKIDQDDRYAWYNLACCYAALGQQEKAINCLREALDIEPDICGELARNNFVFDGLRQNETFNDLLSCYSPS
>CP020664.1|AVQ73511.1|4251900_4253586_-|dihydroxy-acid-dehydratase
MADNYRSRIVTQGTQRSPNRAMLRAVGFGDEDFSKPIIGIANGFSTITPCNMGINDLAMRAEAATRLAGGMPQLFGTITISDGISMGTEGMKYSLVSREVIADSIETVCNGQSLDGVLAIGGCDKNMPGAMIAMARMNIPAIFVYGGTIKPGRYKDCDLTVVSSFEAVGQYSAGKISEEDLIGIERNACPGAGSCGGMFTANTMSSIFEAMGMSLPYSSTMAAEDAEKADSTEESAKVLVEAVRKQILPSQILTRKAFENAISVIMAVGGSTNAVLHLLAISRTIGVELSIDDFETIRQRVPVICDLKPSGRYVTVDLHKAGGIPQVMKILLVNGLLHGDALTISGQTIAEILADIPDQPPSGQDVIRPFSNPVYKEGHLAILKGNLATEGSVAKISGVKTPVITGPARVFESEETCLEAILAGKIKAGDVVVVRYEGPVGGPGMREMLAPTSAIIGAGLGDSVGLITDGRFSGGTYGMVVGHVAPEAAVGGTIALVEEGDQITIDARQRLLSLNVSEEELTRRRNHWQPRPPRYKTGILGKFAKLVSSSSLGALTDLNLF
>CP020664.1|AVQ73512.1|4253731_4253938_+|hypothetical-protein
MIQGTAIGNQDYRNPKFVSATDLTRREDIAPLDNPDVLAQLLAAKRSPRTRHAYAGDLNPHSAPSTVT
>CP020664.1|AVQ73513.1|4254075_4254216_+|hypothetical-protein
MNQSTEIEVKNLDHLGLVAGIIDEIGIVEIINEQVSIERGEIVTAG
>CP020664.1|AVQ74405.1|4254232_4254583_-|transposase
MFRDFKSGGYSLEGSQLAPQYLSKLIIVIAIAYTSATMQGKKIKDMGIQKYVTRPEKRYKGQRRHSSFYVGQHLYHWLQLHQMFPKNIEELMQISRYRLKDYIKGQRAISLALSTF
>CP020664.1|AVQ73514.1|4255615_4255858_-|hypothetical-protein
MKILILKNLIGFGKALKSIIAVKASFFPQWWWLELLKPGNLNNINIQQFWKSLKDIITTDEVFGFIARSQENPLTGGQAS
>CP020664.1|AVQ73515.1|4256024_4256273_-|hypothetical-protein
MVSVKKIQIPEGTGFNRKVAMELANLISAAYNEYEVWDTNKALQQESQLPTVITGSEEFADLEMDSLECQALRYLLWFDRGA

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP020664_12	12.1\|2791196\|18\|CP020664\|CRT	2791196-2791213	18	CP020664.1	2790956-2790973	0	1.0
CP020664_12	12.1\|2791196\|18\|CP020664\|CRT	2791196-2791213	18	CP020664.1	2791031-2791048	0	1.0
CP020664_12	12.1\|2791196\|18\|CP020664\|CRT	2791196-2791213	18	CP020664.1	2791142-2791159	0	1.0
CP020664_12	12.2\|2791250\|27\|CP020664\|CRT	2791250-2791276	27	CP020664.1	2791106-2791132	0	1.0
CP020664_12	12.3\|2791313\|18\|CP020664\|CRT	2791313-2791330	18	CP020664.1	2790956-2790973	0	1.0
CP020664_12	12.3\|2791313\|18\|CP020664\|CRT	2791313-2791330	18	CP020664.1	2791031-2791048	0	1.0
CP020664_12	12.3\|2791313\|18\|CP020664\|CRT	2791313-2791330	18	CP020664.1	2791142-2791159	0	1.0
CP020664_19	19.1\|4533307\|26\|CP020664\|CRISPRCasFinder	4533307-4533332	26	CP020664.1	4532635-4532660	0	1.0
CP020664_20	20.2\|4800725\|18\|CP020664\|CRT	4800725-4800742	18	CP020664.1	4800881-4800898	0	1.0
CP020664_20	20.3\|4800761\|18\|CP020664\|CRT	4800761-4800778	18	CP020664.1	4800881-4800898	0	1.0
CP020664_20	20.5\|4800845\|18\|CP020664\|CRT	4800845-4800862	18	CP020664.1	4800881-4800898	0	1.0
CP020664_19	19.1\|4533307\|26\|CP020664\|CRISPRCasFinder	4533307-4533332	26	CP020664.1	4531984-4532009	1	0.962
CP020664_7	7.1\|1695563\|57\|CP020664\|CRISPRCasFinder	1695563-1695619	57	CP020664.1	1695605-1695661	2	0.965

1. spacer 12.1|2791196|18|CP020664|CRT matches to position: 2790956-2790973, mismatch: 0, identity: 1.0

atgatgagaaacccgctt	CRISPR spacer
atgatgagaaacccgctt	Protospacer
******************

2. spacer 12.1|2791196|18|CP020664|CRT matches to position: 2791031-2791048, mismatch: 0, identity: 1.0

atgatgagaaacccgctt	CRISPR spacer
atgatgagaaacccgctt	Protospacer
******************

3. spacer 12.1|2791196|18|CP020664|CRT matches to position: 2791142-2791159, mismatch: 0, identity: 1.0

atgatgagaaacccgctt	CRISPR spacer
atgatgagaaacccgctt	Protospacer
******************

4. spacer 12.2|2791250|27|CP020664|CRT matches to position: 2791106-2791132, mismatch: 0, identity: 1.0

atgatgagaaagcggagaaagcgggtt	CRISPR spacer
atgatgagaaagcggagaaagcgggtt	Protospacer
***************************

5. spacer 12.3|2791313|18|CP020664|CRT matches to position: 2790956-2790973, mismatch: 0, identity: 1.0

atgatgagaaacccgctt	CRISPR spacer
atgatgagaaacccgctt	Protospacer
******************

6. spacer 12.3|2791313|18|CP020664|CRT matches to position: 2791031-2791048, mismatch: 0, identity: 1.0

atgatgagaaacccgctt	CRISPR spacer
atgatgagaaacccgctt	Protospacer
******************

7. spacer 12.3|2791313|18|CP020664|CRT matches to position: 2791142-2791159, mismatch: 0, identity: 1.0

atgatgagaaacccgctt	CRISPR spacer
atgatgagaaacccgctt	Protospacer
******************

8. spacer 19.1|4533307|26|CP020664|CRISPRCasFinder matches to position: 4532635-4532660, mismatch: 0, identity: 1.0

tccgctcggtttcttgaaagcgtcgc	CRISPR spacer
tccgctcggtttcttgaaagcgtcgc	Protospacer
**************************

9. spacer 20.2|4800725|18|CP020664|CRT matches to position: 4800881-4800898, mismatch: 0, identity: 1.0

cctcaagtcctgccttaa	CRISPR spacer
cctcaagtcctgccttaa	Protospacer
******************

10. spacer 20.3|4800761|18|CP020664|CRT matches to position: 4800881-4800898, mismatch: 0, identity: 1.0

cctcaagtcctgccttaa	CRISPR spacer
cctcaagtcctgccttaa	Protospacer
******************

11. spacer 20.5|4800845|18|CP020664|CRT matches to position: 4800881-4800898, mismatch: 0, identity: 1.0

cctcaagtcctgccttaa	CRISPR spacer
cctcaagtcctgccttaa	Protospacer
******************

12. spacer 19.1|4533307|26|CP020664|CRISPRCasFinder matches to position: 4531984-4532009, mismatch: 1, identity: 0.962

tccgctcggtttcttgaaagcgtcgc	CRISPR spacer
tccgctccgtttcttgaaagcgtcgc	Protospacer
******* ******************

13. spacer 7.1|1695563|57|CP020664|CRISPRCasFinder matches to position: 1695605-1695661, mismatch: 2, identity: 0.965

gaagcgagtttacagttagaacaagagcgtcttaaagctgaagaagcaagtttacaa	CRISPR spacer
gaagcaagtttacaattagaacaagagcgtcttaaagctgaagaagcaagtttacaa	Protospacer
*****.********.******************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP020664_11	11.5\|2435639\|39\|CP020664\|PILER-CR,CRISPRCasFinder,CRT	2435639-2435677	39	LC425515	Uncultured phage DNA, contig: NODE375	822-860	1	0.974
CP020664_11	11.7\|2435787\|37\|CP020664\|PILER-CR,CRISPRCasFinder,CRT	2435787-2435823	37	MT840188	Bacteriophage sp. contig_37 genomic sequence	14-50	2	0.946
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP039210	Piscirickettsia salmonis strain Psal-103 plasmid unnamed1, complete sequence	159810-159832	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP048067	Piscirickettsia salmonis strain Ps-8079A plasmid Ps8079A-p1, complete sequence	152172-152194	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP039033	Piscirickettsia salmonis strain Psal-070 plasmid unnamed1, complete sequence	12056-12078	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038894	Piscirickettsia salmonis strain Psal-006a plasmid unnamed1, complete sequence	177448-177470	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038924	Piscirickettsia salmonis strain Psal-011 plasmid unnamed1, complete sequence	13233-13255	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038953	Piscirickettsia salmonis strain Psal-040 plasmid unnamed1, complete sequence	56991-57013	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038812	Piscirickettsia salmonis strain Psal-001 plasmid unnamed1, complete sequence	144934-144956	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP033942	Piscirickettsia salmonis strain EM-90 plasmid pPSEM90-5, complete sequence	83469-83491	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038892	Piscirickettsia salmonis strain Psal-005 plasmid unnamed1, complete sequence	13233-13255	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038914	Piscirickettsia salmonis strain Psal-010a plasmid unnamed1, complete sequence	12056-12078	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038968	Piscirickettsia salmonis strain Psal-068 plasmid unnamed1, complete sequence	144936-144958	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP039205	Piscirickettsia salmonis strain Psal-182 plasmid unnamed1, complete sequence	16840-16862	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP039042	Piscirickettsia salmonis strain Psal-072 plasmid unnamed2, complete sequence	181856-181878	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038948	Piscirickettsia salmonis strain Psal-028 plasmid unnamed1, complete sequence	51100-51122	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038933	Piscirickettsia salmonis strain Psal-025 plasmid unnamed1, complete sequence	220582-220604	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP039221	Piscirickettsia salmonis strain NVI 5692 plasmid unnamed2, complete sequence	11371-11393	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038973	Piscirickettsia salmonis strain Psal-069 plasmid unnamed1, complete sequence	13233-13255	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP039036	Piscirickettsia salmonis strain Psal-071 plasmid unnamed1, complete sequence	158190-158212	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038887	Piscirickettsia salmonis strain Psal-004 plasmid unnamed1, complete sequence	103001-103023	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP039215	Piscirickettsia salmonis strain Psal-104a plasmid unnamed1, complete sequence	147933-147955	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038938	Piscirickettsia salmonis strain Psal-026 plasmid unnamed1, complete sequence	13516-13538	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038963	Piscirickettsia salmonis strain Psal-051 plasmid unnamed1, complete sequence	171269-171291	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038877	Piscirickettsia salmonis strain Psal-002 plasmid unnamed1, complete sequence	147934-147956	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP038882	Piscirickettsia salmonis strain Psal-003 plasmid unnamed1, complete sequence	103960-103982	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP013779	Piscirickettsia salmonis strain PM51819A plasmid p1PS5, complete sequence	96645-96667	3	0.87
CP020664_17	17.1\|3713451\|23\|CP020664\|PILER-CR	3713451-3713473	23	NZ_CP050945	Piscirickettsia salmonis strain Ps-2192A plasmid Ps2192A-p7, complete sequence	48176-48198	3	0.87
CP020664_17	17.3\|3713604\|26\|CP020664\|PILER-CR	3713604-3713629	26	NZ_CP030855	Runella sp. HYN0085 plasmid unnamed5, complete sequence	36892-36917	3	0.885
CP020664_12	12.2\|2791250\|27\|CP020664\|CRT	2791250-2791276	27	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	69784-69810	5	0.815
CP020664_12	12.2\|2791250\|27\|CP020664\|CRT	2791250-2791276	27	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	346315-346341	5	0.815
CP020664_17	17.2\|3713526\|26\|CP020664\|PILER-CR	3713526-3713551	26	NZ_CP039966	Pseudorhodobacter sp. S12M18 plasmid unnamed2, complete sequence	68991-69016	5	0.808
CP020664_12	12.2\|2791250\|27\|CP020664\|CRT	2791250-2791276	27	NC_030948	Ralstonia phage RSP15 DNA, complete genome	108591-108617	6	0.778
CP020664_5	5.45\|1494215\|35\|CP020664\|CRISPRCasFinder,CRT	1494215-1494249	35	NZ_CP049029	Fluviibacterium aquatile strain SC52 plasmid pSC52_1, complete sequence	369615-369649	7	0.8
CP020664_5	5.2\|1491027\|36\|CP020664\|CRISPRCasFinder,CRT,PILER-CR	1491027-1491062	36	MK288022	Bacillus phage pW4, complete genome	37807-37842	8	0.778
CP020664_5	5.17\|1492135\|37\|CP020664\|CRISPRCasFinder,CRT,PILER-CR	1492135-1492171	37	KC139633	Salmonella phage FSL SP-062 hypothetical proteins, head morphogenesis protein, NinH, hypothetical proteins, deoxyuridine 5'-triphosphate nucleotidohydrolase, and hypothetical proteins genes, complete cds	5201-5237	9	0.757
CP020664_5	5.17\|1492135\|37\|CP020664\|CRISPRCasFinder,CRT,PILER-CR	1492135-1492171	37	KC139649	Salmonella phage FSL SP-069 hypothetical proteins, RdgC exonuclease, hypothetical proteins, TerL, hypothetical proteins, deoxyuridine 5'-triphosphate nucleotidohydrolase, hypothetical proteins, NinH, head morphogenesis protein, hypothetical proteins, capsid related protein, hypothetical proteins, enolase-like protein, hypothetical proteins, tail fiber, hypothetical protein, putative endolysin, hypothetical proteins, and DNA polymerase genes, complete cds	12908-12944	9	0.757
CP020664_15	15.1\|3416417\|46\|CP020664\|CRISPRCasFinder	3416417-3416462	46	NZ_CP043057	Dolichospermum sp. UHCC 0315A plasmid pUHCC0315a, complete sequence	11932-11977	12	0.739
CP020664_2	2.3\|707884\|45\|CP020664\|CRISPRCasFinder,CRT	707884-707928	45	NZ_CP025929	Microcystis aeruginosa NIES-2481 plasmid p1, complete sequence	7831-7875	14	0.689
CP020664_6	6.1\|1540157\|55\|CP020664\|CRISPRCasFinder	1540157-1540211	55	NZ_CP046974	Microcystis aeruginosa FD4 plasmid p1FD4, complete sequence	21543-21597	15	0.727

1. spacer 11.5|2435639|39|CP020664|PILER-CR,CRISPRCasFinder,CRT matches to LC425515 (Uncultured phage DNA, contig: NODE375) position: , mismatch: 1, identity: 0.974

ttgctggtttgatgtccacagcccgaccaaaaatatgct	CRISPR spacer
ttgctggtttgatgtccacagcccgcccaaaaatatgct	Protospacer
************************* *************

2. spacer 11.7|2435787|37|CP020664|PILER-CR,CRISPRCasFinder,CRT matches to MT840188 (Bacteriophage sp. contig_37 genomic sequence) position: , mismatch: 2, identity: 0.946

ccgataatttcgccattttcaactctatcagctaaaa	CRISPR spacer
ccaataatttcgccattctcaactctatcagctaaaa	Protospacer
**.**************.*******************

3. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP039210 (Piscirickettsia salmonis strain Psal-103 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

4. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP048067 (Piscirickettsia salmonis strain Ps-8079A plasmid Ps8079A-p1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

5. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP039033 (Piscirickettsia salmonis strain Psal-070 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

6. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038894 (Piscirickettsia salmonis strain Psal-006a plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

7. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038924 (Piscirickettsia salmonis strain Psal-011 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

8. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038953 (Piscirickettsia salmonis strain Psal-040 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

9. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038812 (Piscirickettsia salmonis strain Psal-001 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

10. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP033942 (Piscirickettsia salmonis strain EM-90 plasmid pPSEM90-5, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

11. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038892 (Piscirickettsia salmonis strain Psal-005 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

12. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038914 (Piscirickettsia salmonis strain Psal-010a plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

13. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038968 (Piscirickettsia salmonis strain Psal-068 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

14. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP039205 (Piscirickettsia salmonis strain Psal-182 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

15. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP039042 (Piscirickettsia salmonis strain Psal-072 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

16. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038948 (Piscirickettsia salmonis strain Psal-028 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

17. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038933 (Piscirickettsia salmonis strain Psal-025 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

18. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP039221 (Piscirickettsia salmonis strain NVI 5692 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

19. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038973 (Piscirickettsia salmonis strain Psal-069 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

20. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP039036 (Piscirickettsia salmonis strain Psal-071 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

21. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038887 (Piscirickettsia salmonis strain Psal-004 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

22. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP039215 (Piscirickettsia salmonis strain Psal-104a plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

23. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038938 (Piscirickettsia salmonis strain Psal-026 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

24. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038963 (Piscirickettsia salmonis strain Psal-051 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

25. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038877 (Piscirickettsia salmonis strain Psal-002 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

26. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP038882 (Piscirickettsia salmonis strain Psal-003 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

27. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP013779 (Piscirickettsia salmonis strain PM51819A plasmid p1PS5, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

28. spacer 17.1|3713451|23|CP020664|PILER-CR matches to NZ_CP050945 (Piscirickettsia salmonis strain Ps-2192A plasmid Ps2192A-p7, complete sequence) position: , mismatch: 3, identity: 0.87

ttttcaattccccctccgtcata	CRISPR spacer
ctttcaattcgccctccgtcatc	Protospacer
.********* ***********

29. spacer 17.3|3713604|26|CP020664|PILER-CR matches to NZ_CP030855 (Runella sp. HYN0085 plasmid unnamed5, complete sequence) position: , mismatch: 3, identity: 0.885

ctattgttgtaaattccccctccact	CRISPR spacer
ccattgttgtacatgccccctccact	Protospacer
*.********* ** ***********

30. spacer 12.2|2791250|27|CP020664|CRT matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 5, identity: 0.815

atgatgagaaagcggagaaagcgggtt	CRISPR spacer
tcgttgagaaagccgagaaagcgggtc	Protospacer
 .* ********* ************.

31. spacer 12.2|2791250|27|CP020664|CRT matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

atgatgagaaagcggagaaagcgggtt	CRISPR spacer
tcgttgagaaagccgagaaagcgggtc	Protospacer
 .* ********* ************.

32. spacer 17.2|3713526|26|CP020664|PILER-CR matches to NZ_CP039966 (Pseudorhodobacter sp. S12M18 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.808

tagttgtaaatcccccctccccaact	CRISPR spacer
tagtggaaaatcccccctccccataa	Protospacer
**** * ****************

33. spacer 12.2|2791250|27|CP020664|CRT matches to NC_030948 (Ralstonia phage RSP15 DNA, complete genome) position: , mismatch: 6, identity: 0.778

atgatgagaaagcggagaaagcgggtt	CRISPR spacer
ttgatgaggaagcggagaaagcatata	Protospacer
 *******.*************. .*

34. spacer 5.45|1494215|35|CP020664|CRISPRCasFinder,CRT matches to NZ_CP049029 (Fluviibacterium aquatile strain SC52 plasmid pSC52_1, complete sequence) position: , mismatch: 7, identity: 0.8

ctgaaattcagatcaaaatcatcgccgcgattgtt	CRISPR spacer
ctgaaattcagatcaagaacatcgccaagagtttc	Protospacer
****************.* *******. ** * *.

35. spacer 5.2|1491027|36|CP020664|CRISPRCasFinder,CRT,PILER-CR matches to MK288022 (Bacillus phage pW4, complete genome) position: , mismatch: 8, identity: 0.778

tcgtgact-atgcgacaggtgaatgggttgcattgac	CRISPR spacer
-cacaactaatgctacagttgaatgggttgcattgta	Protospacer
 *...*** **** **** ****************

36. spacer 5.17|1492135|37|CP020664|CRISPRCasFinder,CRT,PILER-CR matches to KC139633 (Salmonella phage FSL SP-062 hypothetical proteins, head morphogenesis protein, NinH, hypothetical proteins, deoxyuridine 5'-triphosphate nucleotidohydrolase, and hypothetical proteins genes, complete cds) position: , mismatch: 9, identity: 0.757

atttaaaaatgccgcaggtgattcggcctctgacgtt	CRISPR spacer
atttaaaaatgcagcaggtgatacggttgcttatctg	Protospacer
************ ********* ***.. ** *. *

37. spacer 5.17|1492135|37|CP020664|CRISPRCasFinder,CRT,PILER-CR matches to KC139649 (Salmonella phage FSL SP-069 hypothetical proteins, RdgC exonuclease, hypothetical proteins, TerL, hypothetical proteins, deoxyuridine 5'-triphosphate nucleotidohydrolase, hypothetical proteins, NinH, head morphogenesis protein, hypothetical proteins, capsid related protein, hypothetical proteins, enolase-like protein, hypothetical proteins, tail fiber, hypothetical protein, putative endolysin, hypothetical proteins, and DNA polymerase genes, complete cds) position: , mismatch: 9, identity: 0.757

atttaaaaatgccgcaggtgattcggcctctgacgtt	CRISPR spacer
atttaaaaatgcagcaggtgatacggttgcttatctg	Protospacer
************ ********* ***.. ** *. *

38. spacer 15.1|3416417|46|CP020664|CRISPRCasFinder matches to NZ_CP043057 (Dolichospermum sp. UHCC 0315A plasmid pUHCC0315a, complete sequence) position: , mismatch: 12, identity: 0.739

ctatagataaggtaggttgggttgacgcaaggaaacccaacgcccg	CRISPR spacer
gtgagaagaaagtaggttgggttgacgcaaggaaacccaacatgat	Protospacer
 *. ..* **.******************************..

39. spacer 2.3|707884|45|CP020664|CRISPRCasFinder,CRT matches to NZ_CP025929 (Microcystis aeruginosa NIES-2481 plasmid p1, complete sequence) position: , mismatch: 14, identity: 0.689

ctgcgagtagagagtagggttaattcatgaattaaccctacaaat---------	CRISPR spacer
---------atgtgtagggttaattaatgaattaaccctacaattttgcggaat	Protospacer
         . * ************ ***************** *

40. spacer 6.1|1540157|55|CP020664|CRISPRCasFinder matches to NZ_CP046974 (Microcystis aeruginosa FD4 plasmid p1FD4, complete sequence) position: , mismatch: 15, identity: 0.727

ctcatgcaaaacggag-------aataaataagtagtcgtgcaaaattaatttcctagtg	CRISPR spacer
-------aaaactccatcgccttaattaataagtagtcgtgcaaaataaatttcctagtg	Protospacer
       *****   .       *** ******************** ************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

645410 : 695430

Bacillus_virus(23.53%)

tRNA,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ70497.1\|645410_646694_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.8e-82	41.2
AVQ70498.1\|646900_647080_+	hypothetical protein	NA	NA	NA	NA
AVQ70499.1\|647082_647682_+\|transposase	transposase	G3MB42	Bacillus_virus	4.9e-29	38.7
AVQ70500.1\|647697_648306_+\|transposase	transposase	G3MB42	Bacillus_virus	1.9e-44	46.3
AVQ70501.1\|648400_649006_+	peptidase M23	V5R8R0	Arthrobacter_phage	5.0e-05	33.1
AVQ70502.1\|649002_650241_-\|transposase	transposase	G3MB42	Bacillus_virus	9.8e-64	38.2
AVQ70503.1\|650212_650806_-\|transposase	IS607 family transposase	F9VHY9	Thermus_phage	1.6e-51	58.5
AVQ70504.1\|651021_651984_+	glycosyltransferase	NA	NA	NA	NA
AVQ74200.1\|652045_652555_-	metal-binding protein	NA	NA	NA	NA
AVQ70505.1\|652852_653806_+	lipoprotein NlpI	NA	NA	NA	NA
AVQ70506.1\|653820_656748_-	DEAD/DEAH box helicase	E3T5F3	Cafeteria_roenbergensis_virus	4.1e-60	29.8
AVQ70507.1\|656871_657144_+	hypothetical protein	NA	NA	NA	NA
AVQ70508.1\|658215_660123_+	squalene-hopene cyclase	NA	NA	NA	NA
AVQ70509.1\|660183_660579_-	transcriptional regulator	NA	NA	NA	NA
AVQ70510.1\|660804_661113_-	hypothetical protein	A0A0P0ZE17	Stx2-converting_phage	1.3e-12	41.8
AVQ70511.1\|661551_662547_+	glycosyltransferase	NA	NA	NA	NA
AVQ70512.1\|662757_663663_+	methionine synthase	NA	NA	NA	NA
AVQ70513.1\|663824_664115_-	hypothetical protein	NA	NA	NA	NA
AVQ70514.1\|664117_664795_-	hypothetical protein	NA	NA	NA	NA
AVQ70515.1\|665214_665427_+	hypothetical protein	NA	NA	NA	NA
AVQ70516.1\|665567_666458_+	indole-3-glycerol phosphate synthase	A0A0P0IR83	Acinetobacter_phage	4.0e-43	42.6
AVQ70517.1\|666736_667891_+	class V aminotransferase	NA	NA	NA	NA
AVQ70518.1\|667887_668097_-	hypothetical protein	NA	NA	NA	NA
AVQ70519.1\|668231_669140_-	peptidase	A0A0K2CNY2	Brevibacillus_phage	2.4e-11	35.7
AVQ74201.1\|669159_670458_-	homoserine dehydrogenase	NA	NA	NA	NA
AVQ70520.1\|670599_671955_-	glycolate oxidase	NA	NA	NA	NA
AVQ70521.1\|671964_673251_-	FAD-binding oxidoreductase	NA	NA	NA	NA
AVQ70522.1\|673628_674816_+	LL-diaminopimelate aminotransferase	A0A142C026	Faustovirus	9.6e-08	31.2
AVQ70523.1\|674910_675642_+	hypothetical protein	NA	NA	NA	NA
AVQ70524.1\|675725_676016_-	DUF4164 domain-containing protein	NA	NA	NA	NA
AVQ70525.1\|676295_677321_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.5e-81	46.1
AVQ70526.1\|677570_678707_-	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofH	NA	NA	NA	NA
AVQ70527.1\|678844_679546_-	photosystem II biogenesis protein Psp29	NA	NA	NA	NA
AVQ70528.1\|679899_680364_+	SsrA-binding protein	W5RAM5	Staphylococcus_phage	2.1e-35	52.4
AVQ70529.1\|680465_682277_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
AVQ74202.1\|683140_684820_-	pyridoxal-dependent decarboxylase, pyridoxal binding domain protein	NA	NA	NA	NA
AVQ70530.1\|685291_685930_-	steroid 5-alpha reductase	NA	NA	NA	NA
AVQ70531.1\|686342_687566_-	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
AVQ70532.1\|687839_688145_+	hypothetical protein	NA	NA	NA	NA
AVQ70533.1\|688187_689924_+	hypothetical protein	E5ERK4	Ostreococcus_lucimarinus_virus	1.3e-66	33.7
AVQ74203.1\|689968_690691_+	serine/threonine protein phosphatase	NA	NA	NA	NA
AVQ70534.1\|690905_692279_-	hypothetical protein	NA	NA	NA	NA
AVQ70535.1\|692314_693433_-	hybrid sensor histidine kinase/response regulator	A0A1V0SGX0	Hokovirus	4.9e-22	30.0
AVQ70536.1\|693626_694865_-\|transposase	transposase	G3MB42	Bacillus_virus	9.8e-64	38.2
AVQ70537.1\|694836_695430_-\|transposase	IS607 family transposase	F9VHY9	Thermus_phage	1.6e-51	58.5

DBSCAN-SWA_2

1320845 : 1390418

Burkholderia_phage(25.0%)

tRNA,bacteriocin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ71066.1\|1320845_1321142_+\|tRNA	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	NA	NA	NA	NA
AVQ71067.1\|1321249_1321651_+	mannose-6-phosphate isomerase	NA	NA	NA	NA
AVQ74242.1\|1322164_1322356_+	hypothetical protein	NA	NA	NA	NA
AVQ71068.1\|1322403_1322589_-	hypothetical protein	NA	NA	NA	NA
AVQ71069.1\|1322724_1323096_+	hypothetical protein	NA	NA	NA	NA
AVQ71070.1\|1323661_1324495_+	nucleoside triphosphate pyrophosphohydrolase	NA	NA	NA	NA
AVQ71071.1\|1324494_1325070_+	S26 family signal peptidase	NA	NA	NA	NA
AVQ71072.1\|1325080_1325569_-	universal stress protein UspA	NA	NA	NA	NA
AVQ74243.1\|1325587_1326505_+	ribonuclease D	NA	NA	NA	NA
AVQ71073.1\|1326603_1327458_+	prephenate dehydratase	NA	NA	NA	NA
AVQ71074.1\|1327507_1329427_-	two-component sensor histidine kinase	A0A1V0SGX0	Hokovirus	1.7e-30	34.6
AVQ71075.1\|1329518_1330199_+	riboflavin deaminase	NA	NA	NA	NA
AVQ71076.1\|1330235_1331426_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AVQ71077.1\|1331578_1333075_-\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AVQ74244.1\|1333270_1333456_+	hypothetical protein	NA	NA	NA	NA
AVQ71078.1\|1333536_1334121_-	rubrerythrin family protein	NA	NA	NA	NA
AVQ71079.1\|1334253_1336386_+\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
AVQ74245.1\|1336804_1337194_+	hypothetical protein	NA	NA	NA	NA
AVQ71080.1\|1337274_1338348_+	magnesium chelatase ATPase subunit I	NA	NA	NA	NA
AVQ71081.1\|1338475_1339843_+	ATPase	C7BGE8	Burkholderia_phage	7.9e-14	42.4
AVQ71082.1\|1339839_1340529_+	HNH endonuclease	NA	NA	NA	NA
AVQ71083.1\|1340603_1341695_+	glycosyl transferase	NA	NA	NA	NA
AVQ71084.1\|1341816_1343808_+	hypothetical protein	E5ES62	Bathycoccus_sp._RCC1105_virus	2.5e-45	27.6
AVQ74246.1\|1343897_1345202_-	cytochrome P450	NA	NA	NA	NA
AVQ71085.1\|1345411_1346608_-	alanine racemase	NA	NA	NA	NA
AVQ71086.1\|1348959_1349169_-	hypothetical protein	NA	NA	NA	NA
AVQ74247.1\|1351462_1351717_+	endonuclease	A0A1J0GW84	Streptomyces_phage	4.7e-05	46.3
AVQ74248.1\|1351763_1352933_+\|transposase	transposase	A0A0H3UZC2	Geobacillus_virus	4.9e-73	41.6
AVQ71087.1\|1352929_1353115_+	hypothetical protein	NA	NA	NA	NA
AVQ71088.1\|1353364_1353640_+	polyhydroxyalkanoate biosynthesis repressor PhaR	NA	NA	NA	NA
AVQ71089.1\|1355237_1356434_-	hypothetical protein	NA	NA	NA	NA
AVQ71090.1\|1356454_1356985_-	hypothetical protein	NA	NA	NA	NA
AVQ71091.1\|1357587_1358040_-	hypothetical protein	NA	NA	NA	NA
AVQ71092.1\|1358610_1358940_-	hypothetical protein	K4NX81	Burkholderia_phage	7.4e-11	43.9
AVQ71093.1\|1358970_1360185_-	cysteine lyase	NA	NA	NA	NA
AVQ74249.1\|1360498_1361935_+	recombinase B	NA	NA	NA	NA
AVQ71094.1\|1362430_1362673_+	hypothetical protein	NA	NA	NA	NA
AVQ71095.1\|1362683_1363064_-	hypothetical protein	NA	NA	NA	NA
AVQ71096.1\|1363302_1363911_+	methylthioribulose-1-phosphate dehydratase	NA	NA	NA	NA
AVQ74250.1\|1364429_1364765_+	hypothetical protein	NA	NA	NA	NA
AVQ71097.1\|1365033_1365957_+	restriction endonuclease	NA	NA	NA	NA
AVQ71098.1\|1366197_1366779_+	phycobiliprotein lyase	NA	NA	NA	NA
AVQ71099.1\|1366981_1367734_+	phycobilisome rod-core linker polypeptide CpcG	NA	NA	NA	NA
AVQ71100.1\|1369834_1371652_-	hypothetical protein	NA	NA	NA	NA
AVQ71101.1\|1372274_1372892_-	hypothetical protein	NA	NA	NA	NA
AVQ71102.1\|1372938_1373928_-	serine/threonine protein kinase	I6PD73	Cronobacter_phage	5.0e-10	41.8
AVQ71103.1\|1374423_1375482_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
AVQ71104.1\|1375584_1376220_+	hypothetical protein	NA	NA	NA	NA
AVQ71105.1\|1376649_1377627_-	alpha/beta hydrolase	NA	NA	NA	NA
AVQ71106.1\|1378081_1378936_+	universal stress protein UspA	NA	NA	NA	NA
AVQ71107.1\|1378939_1379182_-	hypothetical protein	NA	NA	NA	NA
AVQ71108.1\|1379093_1379534_-	hypothetical protein	A0A1P8DJJ6	Virus_Rctr41k	4.0e-12	41.1
AVQ71109.1\|1379633_1380791_+\|transposase	IS630 family transposase	NA	NA	NA	NA
AVQ71110.1\|1381071_1381338_+	hypothetical protein	NA	NA	NA	NA
AVQ74251.1\|1381451_1382078_-\|transposase	IS630 family transposase	NA	NA	NA	NA
AVQ71111.1\|1382140_1382590_-	hypothetical protein	NA	NA	NA	NA
AVQ71112.1\|1382748_1383222_-\|transposase	transposase	NA	NA	NA	NA
AVQ71113.1\|1386379_1388590_-	hypothetical protein	NA	NA	NA	NA
AVQ71114.1\|1388885_1390418_-\|bacteriocin	NHLP bacteriocin system secretion protein	NA	NA	NA	NA

DBSCAN-SWA_3

1857969 : 1937959

Dishui_lake_phycodnavirus(15.38%)

tail,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ71485.1\|1857969_1859187_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
AVQ71486.1\|1859187_1870113_+	hypothetical protein	A0A0K2FL64	Brevibacillus_phage	1.3e-13	27.8
AVQ71487.1\|1873986_1874679_-	dethiobiotin synthase	NA	NA	NA	NA
AVQ71488.1\|1875416_1877270_+	acetolactate synthase, large subunit, biosynthetic type	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	8.3e-59	31.7
AVQ71489.1\|1877504_1878767_-	phycocyanin operon protein Y	NA	NA	NA	NA
AVQ71490.1\|1878958_1879192_+	hypothetical protein	NA	NA	NA	NA
AVQ71491.1\|1879339_1880269_+	glycosyl transferase family 2	NA	NA	NA	NA
AVQ71492.1\|1880374_1881952_+	phosphoglycerate dehydrogenase	A0A1V0SBV6	Catovirus	9.3e-43	31.0
AVQ71493.1\|1882218_1883115_+	ribosomal protein L11 methyltransferase	NA	NA	NA	NA
AVQ71494.1\|1883031_1883346_-	hypothetical protein	NA	NA	NA	NA
AVQ71495.1\|1883350_1884160_-	modification methylase	A0A2K9R7J9	Dishui_lake_phycodnavirus	1.3e-37	36.7
AVQ71496.1\|1884275_1884632_-	PemK family transcriptional regulator	NA	NA	NA	NA
AVQ71497.1\|1884628_1884877_-	hypothetical protein	NA	NA	NA	NA
AVQ74271.1\|1885251_1885827_-	hypothetical protein	NA	NA	NA	NA
AVQ71498.1\|1886628_1887438_-	modification methylase	A0A2K9R7J9	Dishui_lake_phycodnavirus	1.3e-37	36.7
AVQ71499.1\|1887542_1887746_-	hypothetical protein	NA	NA	NA	NA
AVQ71500.1\|1887768_1888182_-	hypothetical protein	NA	NA	NA	NA
AVQ71501.1\|1888298_1890230_-	penicillin-binding protein	NA	NA	NA	NA
AVQ71502.1\|1890379_1890865_-	hypothetical protein	NA	NA	NA	NA
AVQ71503.1\|1891249_1892014_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
AVQ71504.1\|1892141_1892753_-	ribonucleoside-triphosphate reductase	A0A1Z1LY78	Serratia_phage	6.6e-13	30.3
AVQ71505.1\|1892833_1894015_-	RNA-splicing ligase RtcB	A0A1V0EEW8	Caulobacter_phage	1.3e-102	53.0
AVQ71506.1\|1894377_1896282_+	molecular chaperone DnaK	G8DDB7	Micromonas_pusilla_virus	1.6e-150	50.9
AVQ71507.1\|1896530_1897739_+	sodium:glutamate symporter	NA	NA	NA	NA
AVQ71508.1\|1898162_1898570_-	PIN domain-containing protein	NA	NA	NA	NA
AVQ71509.1\|1898575_1898836_-	hypothetical protein	NA	NA	NA	NA
AVQ71510.1\|1901228_1901429_-	hypothetical protein	NA	NA	NA	NA
AVQ71511.1\|1902031_1903303_+	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
AVQ71512.1\|1903663_1904626_-	protochlorophyllide oxidoreductase	NA	NA	NA	NA
AVQ71513.1\|1904873_1905875_-	penicillin-binding protein activator LpoB	NA	NA	NA	NA
AVQ71514.1\|1906081_1907098_-\|transposase	IS4 family transposase	NA	NA	NA	NA
AVQ71515.1\|1908784_1908955_-	hypothetical protein	NA	NA	NA	NA
AVQ74272.1\|1909060_1909435_-	6-carboxytetrahydropterin synthase QueD	NA	NA	NA	NA
AVQ71516.1\|1909990_1910551_-	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
AVQ74273.1\|1910941_1911319_+	transcriptional regulator	A0A222YXG1	Escherichia_phage	1.1e-07	34.4
AVQ71517.1\|1911480_1912374_+	beta-carotene hydroxylase	NA	NA	NA	NA
AVQ71518.1\|1912493_1912811_+	hypothetical protein	NA	NA	NA	NA
AVQ71519.1\|1912811_1913366_-	hypothetical protein	NA	NA	NA	NA
AVQ71520.1\|1913504_1914305_-	exodeoxyribonuclease III	NA	NA	NA	NA
AVQ71521.1\|1914327_1914912_-	chorismate-binding protein	C7BVI4	Synechococcus_phage	1.1e-20	35.9
AVQ71522.1\|1915011_1915470_-	50S ribosomal protein L9	NA	NA	NA	NA
AVQ71523.1\|1916045_1916402_-	hypothetical protein	NA	NA	NA	NA
AVQ71524.1\|1916620_1917136_+\|transposase	transposase	NA	NA	NA	NA
AVQ71525.1\|1917472_1918690_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
AVQ74274.1\|1919140_1919350_+\|transposase	transposase	NA	NA	NA	NA
AVQ71526.1\|1919300_1919483_+	hypothetical protein	NA	NA	NA	NA
AVQ71527.1\|1919534_1920608_-	oxidoreductase	NA	NA	NA	NA
AVQ71528.1\|1920841_1921414_+	shikimate kinase	NA	NA	NA	NA
AVQ71529.1\|1921413_1921737_+	cupin	NA	NA	NA	NA
AVQ71530.1\|1921751_1922924_-	coproporphyrinogen III oxidase	NA	NA	NA	NA
AVQ71531.1\|1924020_1924833_-	glutamate racemase	NA	NA	NA	NA
AVQ71532.1\|1924930_1926829_-	N-acetylmuramoyl-L-alanine amidase	A0A0N9SGH1	Paenibacillus_phage	2.1e-25	43.3
AVQ71533.1\|1927243_1928632_-	sodium:proton antiporter	NA	NA	NA	NA
AVQ71534.1\|1928748_1929975_-	sodium:dicarboxylate symporter	NA	NA	NA	NA
AVQ71535.1\|1930137_1932171_-	elongation factor G	E4ZFJ7	Streptococcus_phage	3.7e-36	24.3
AVQ71536.1\|1932551_1933643_+	GTP-binding protein YchF	NA	NA	NA	NA
AVQ71537.1\|1934013_1936047_+	restriction endonuclease subunit M	B3GAM1	uncultured_virus	6.8e-30	28.1
AVQ71538.1\|1936222_1937959_-\|tail	tail length tape measure protein	NA	NA	NA	NA

DBSCAN-SWA_4

2146535 : 2219251

Thermobifida_phage(12.5%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ71728.1\|2146535_2147750_-\|transposase	transposase	A0A0R8V9X2	Thermobifida_phage	7.5e-117	57.6
AVQ71729.1\|2147671_2147854_-	hypothetical protein	NA	NA	NA	NA
AVQ71730.1\|2147852_2148362_+\|transposase	transposase	NA	NA	NA	NA
AVQ71731.1\|2148783_2149104_+	hypothetical protein	NA	NA	NA	NA
AVQ71732.1\|2149093_2149537_+	endonuclease	NA	NA	NA	NA
AVQ71733.1\|2149683_2149965_+	plasmid maintenance system killer family protein	NA	NA	NA	NA
AVQ71734.1\|2149981_2150296_+	addiction module antidote protein, HigA family	A0A2P1MXE5	Escherichia_phage	1.7e-09	41.7
AVQ71735.1\|2150329_2150671_-	hypothetical protein	NA	NA	NA	NA
AVQ71736.1\|2150837_2152157_-	Hrp-dependent type III effector protein	NA	NA	NA	NA
AVQ71737.1\|2152306_2153143_+	acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase	NA	NA	NA	NA
AVQ74289.1\|2153336_2154542_+	lipid-A-disaccharide synthase	NA	NA	NA	NA
AVQ74290.1\|2154706_2157652_-	glycine dehydrogenase (aminomethyl-transferring)	M4QFZ1	Prochlorococcus_phage	1.0e-276	52.9
AVQ71738.1\|2157802_2159428_-	phospholipid carrier-dependent glycosyltransferase	NA	NA	NA	NA
AVQ71739.1\|2159639_2159849_+	hypothetical protein	NA	NA	NA	NA
AVQ71740.1\|2159879_2160689_+	4-amino-4-deoxychorismate lyase	NA	NA	NA	NA
AVQ71741.1\|2160745_2161096_-	single-stranded DNA-binding protein	Q1MVN2	Enterobacteria_phage	1.4e-12	31.1
AVQ71742.1\|2161318_2162356_+	rod shape-determining protein	NA	NA	NA	NA
AVQ71743.1\|2162429_2163179_+	rod shape-determining protein MreC	NA	NA	NA	NA
AVQ71744.1\|2163145_2163727_+	rod shape-determining protein MreD	NA	NA	NA	NA
AVQ71745.1\|2163846_2166297_+	penicillin-binding protein	NA	NA	NA	NA
AVQ71746.1\|2166626_2168387_+	peptidase M61	NA	NA	NA	NA
AVQ71747.1\|2168410_2169337_+	branched chain amino acid aminotransferase	NA	NA	NA	NA
AVQ71748.1\|2169914_2171435_+	circadian clock protein KaiC	NA	NA	NA	NA
AVQ71749.1\|2171509_2172340_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
AVQ71750.1\|2172423_2175048_+	trans-splicing intein-formed DNA polymerase III subunit alpha N-terminal partner DnaE-N	A0A1C9LWZ5	Streptomyces_phage	7.7e-159	40.3
AVQ71751.1\|2180434_2181460_+	ABC transporter permease	NA	NA	NA	NA
AVQ71752.1\|2181653_2182640_-	hypothetical protein	NA	NA	NA	NA
AVQ71753.1\|2182719_2183082_-	hypothetical protein	NA	NA	NA	NA
AVQ71754.1\|2183761_2184778_+\|transposase	IS4 family transposase	NA	NA	NA	NA
AVQ71755.1\|2184853_2185771_-	glycosyltransferase	NA	NA	NA	NA
AVQ71756.1\|2186031_2186826_+	tryptophan synthase subunit alpha	NA	NA	NA	NA
AVQ71757.1\|2189399_2190212_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	6.3e-43	41.2
AVQ71758.1\|2190259_2190844_+	hypothetical protein	NA	NA	NA	NA
AVQ71759.1\|2191277_2191724_+	hypothetical protein	NA	NA	NA	NA
AVQ71760.1\|2191757_2192069_-	DUF4164 domain-containing protein	NA	NA	NA	NA
AVQ71761.1\|2192131_2192335_-	transcriptional regulator	NA	NA	NA	NA
AVQ71762.1\|2192740_2193742_+	4Fe-4S ferredoxin	NA	NA	NA	NA
AVQ74291.1\|2193891_2195610_+	single-stranded DNA-binding protein	NA	NA	NA	NA
AVQ71763.1\|2195645_2197049_+	hypothetical protein	NA	NA	NA	NA
AVQ71764.1\|2197293_2197722_-\|protease	aspartyl protease	NA	NA	NA	NA
AVQ71765.1\|2197726_2198032_-	hypothetical protein	NA	NA	NA	NA
AVQ71766.1\|2198052_2198292_-	NAD(P)H-quinone oxidoreductase subunit L	NA	NA	NA	NA
AVQ71767.1\|2198833_2199472_-	carotenoid oxygenase	NA	NA	NA	NA
AVQ71768.1\|2199461_2200409_-	epoxyqueuosine reductase	NA	NA	NA	NA
AVQ71769.1\|2200542_2201028_+	Orange carotenoid protein	NA	NA	NA	NA
AVQ71770.1\|2201332_2202031_+	DUF3782 domain-containing protein	NA	NA	NA	NA
AVQ71771.1\|2202458_2203889_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	6.9e-37	28.2
AVQ71772.1\|2204048_2204225_+	twin-arginine translocase TatA/TatE family subunit	NA	NA	NA	NA
AVQ71773.1\|2204633_2206037_-	hypothetical protein	NA	NA	NA	NA
AVQ74292.1\|2206215_2206398_-	hypothetical protein	NA	NA	NA	NA
AVQ71774.1\|2206623_2209869_-	carbamoyl phosphate synthase large subunit	NA	NA	NA	NA
AVQ71775.1\|2210156_2211197_+	adenosine deaminase	NA	NA	NA	NA
AVQ71776.1\|2211268_2211676_-	MAPEG family protein	NA	NA	NA	NA
AVQ71777.1\|2211684_2212191_-	DNA recombination-mediator protein A	NA	NA	NA	NA
AVQ71778.1\|2212403_2213645_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AVQ71779.1\|2213644_2214082_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
AVQ71780.1\|2214755_2215928_+\|transposase	transposase	A0A7P9	Microcystis_virus	3.6e-217	98.7
AVQ71781.1\|2216013_2216865_-	hypothetical protein	NA	NA	NA	NA
AVQ71782.1\|2216861_2218124_-	hypothetical protein	NA	NA	NA	NA
AVQ71783.1\|2218435_2219251_-\|protease	membrane protease subunit, stomatin/prohibitin	NA	NA	NA	NA

DBSCAN-SWA_5

2279120 : 2364509

Leptospira_phage(10.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ74294.1\|2279120_2279747_-\|transposase	IS630 family transposase	NA	NA	NA	NA
AVQ71835.1\|2279809_2280259_-	hypothetical protein	NA	NA	NA	NA
AVQ71836.1\|2280440_2283542_-	acriflavine resistance protein B	S5VTK5	Leptospira_phage	5.6e-07	22.1
AVQ71837.1\|2283814_2285359_-	efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
AVQ71838.1\|2285426_2286392_-	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
AVQ74295.1\|2287392_2288154_-\|transposase	IS1 family transposase	NA	NA	NA	NA
AVQ71839.1\|2288644_2289394_-	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
AVQ71840.1\|2289594_2290872_-	dehydrogenase	NA	NA	NA	NA
AVQ71841.1\|2290937_2292110_-	MFS transporter	NA	NA	NA	NA
AVQ71842.1\|2292145_2293720_-	2-nitropropane dioxygenase	NA	NA	NA	NA
AVQ71843.1\|2293861_2298865_-	short-chain dehydrogenase	NA	NA	NA	NA
AVQ74296.1\|2298910_2300668_-	polyketide synthase	NA	NA	NA	NA
AVQ71844.1\|2300838_2301558_-	hypothetical protein	NA	NA	NA	NA
AVQ71845.1\|2301614_2305436_-	polyketide synthase	D0R7J2	Paenibacillus_phage	1.9e-20	27.5
AVQ71846.1\|2306037_2306262_+	hypothetical protein	NA	NA	NA	NA
AVQ71847.1\|2306310_2306502_-	hypothetical protein	NA	NA	NA	NA
AVQ71848.1\|2307423_2308434_-	sugar transferase	NA	NA	NA	NA
AVQ71849.1\|2308672_2310178_-	hypothetical protein	NA	NA	NA	NA
AVQ71850.1\|2310397_2311747_-	two-component sensor histidine kinase	NA	NA	NA	NA
AVQ71851.1\|2312066_2312540_+	EVE domain-containing protein	NA	NA	NA	NA
AVQ71852.1\|2312543_2313398_+	primosomal protein	H7BVU6	unidentified_phage	4.0e-08	27.1
AVQ71853.1\|2313883_2314072_-	C4-dicarboxylate ABC transporter	NA	NA	NA	NA
AVQ74297.1\|2314196_2315855_-\|transposase	IS1634 family transposase	NA	NA	NA	NA
AVQ71854.1\|2316373_2319943_+	N-6 DNA methylase	B3GAM1	uncultured_virus	2.7e-21	33.3
AVQ71855.1\|2320104_2321292_-	glycosyl transferase	NA	NA	NA	NA
AVQ71856.1\|2321293_2322208_-	hypothetical protein	NA	NA	NA	NA
AVQ71857.1\|2322643_2324152_+	serine/threonine protein kinase	M1PCM5	Moumouvirus	6.2e-20	32.5
AVQ71858.1\|2324425_2326015_-	glycoside hydrolase	NA	NA	NA	NA
AVQ71859.1\|2326162_2327317_+	histidine kinase	W8CYF6	Bacillus_phage	1.2e-18	28.5
AVQ71860.1\|2327294_2328122_-	alpha/beta hydrolase	NA	NA	NA	NA
AVQ71861.1\|2330556_2332062_+	hypothetical protein	A0A2H4UVE2	Bodo_saltans_virus	1.8e-11	24.1
AVQ71862.1\|2332158_2332383_+	hypothetical protein	NA	NA	NA	NA
AVQ71863.1\|2332366_2332789_+	PIN domain nuclease	NA	NA	NA	NA
AVQ71864.1\|2333236_2333941_+	ribonuclease III	I3UKW9	Ostreococcus_lucimarinus_virus	2.9e-12	29.3
AVQ71865.1\|2333957_2335028_-	hypothetical protein	NA	NA	NA	NA
AVQ71866.1\|2335115_2335409_-	hypothetical protein	NA	NA	NA	NA
AVQ71867.1\|2335752_2337993_+	glycoside hydrolase	NA	NA	NA	NA
AVQ71868.1\|2338057_2338240_-	hypothetical protein	NA	NA	NA	NA
AVQ71869.1\|2338305_2339496_-	PBS lyase	NA	NA	NA	NA
AVQ71870.1\|2339607_2340384_-	cobalt ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.1e-15	32.0
AVQ71871.1\|2340398_2341172_-	cobalt ECF transporter T component CbiQ	NA	NA	NA	NA
AVQ71872.1\|2341307_2341631_-	cobalt transport protein	NA	NA	NA	NA
AVQ71873.1\|2341641_2342385_-	cobalamin biosynthesis protein CbiM	NA	NA	NA	NA
AVQ71874.1\|2342934_2343435_+	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
AVQ71875.1\|2343726_2347392_-	magnesium chelatase subunit H	NA	NA	NA	NA
AVQ71876.1\|2347467_2349198_-	flavin oxidoreductase	NA	NA	NA	NA
AVQ71877.1\|2349563_2349854_+	hypothetical protein	NA	NA	NA	NA
AVQ74298.1\|2350282_2351239_+\|transposase	IS110 family transposase	Q75QL1	Wolbachia_phage	4.5e-32	36.0
AVQ71878.1\|2351515_2353780_-	carbamoyltransferase HypF	NA	NA	NA	NA
AVQ71879.1\|2353830_2354505_-\|protease	ATP-dependent Zn protease	NA	NA	NA	NA
AVQ71880.1\|2354604_2354943_-	hypothetical protein	NA	NA	NA	NA
AVQ71881.1\|2355944_2356751_+	histidinol-phosphatase	NA	NA	NA	NA
AVQ71882.1\|2356799_2357507_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
AVQ71883.1\|2357801_2357990_+	hypothetical protein	NA	NA	NA	NA
AVQ71884.1\|2359466_2359748_-	plasmid stabilization protein	NA	NA	NA	NA
AVQ71885.1\|2359744_2359960_-	hypothetical protein	NA	NA	NA	NA
AVQ71886.1\|2360259_2360934_-	hypothetical protein	NA	NA	NA	NA
AVQ71887.1\|2360936_2361131_-	DUF3252 domain-containing protein	NA	NA	NA	NA
AVQ74299.1\|2362850_2364509_+\|transposase	IS1634 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

2729740 : 2796519

Wolbachia_phage(27.27%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ72210.1\|2729740_2730688_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
AVQ72211.1\|2731277_2733131_-	cell division protein FtsH	M4QMW8	Micromonas_pusilla_virus	1.6e-134	46.1
AVQ72212.1\|2733403_2734651_+	RNA polymerase subunit sigma-70	NA	NA	NA	NA
AVQ72213.1\|2734653_2735781_+	hypothetical protein	NA	NA	NA	NA
AVQ72214.1\|2735796_2738265_+	nucleotide cyclase	NA	NA	NA	NA
AVQ72215.1\|2738330_2741795_+	hypothetical protein	NA	NA	NA	NA
AVQ72216.1\|2741812_2742001_+	addiction module toxin, HicA family	A0A0R6PJD4	Moraxella_phage	1.3e-15	60.0
AVQ72217.1\|2742012_2742279_+	HicB family protein	A0A0K2CYJ8	Paenibacillus_phage	6.2e-08	53.8
AVQ72218.1\|2742299_2742578_+	hypothetical protein	NA	NA	NA	NA
AVQ74322.1\|2742641_2743598_-\|transposase	IS110 family transposase	Q75QL1	Wolbachia_phage	4.5e-32	36.0
AVQ72219.1\|2743922_2744207_+	hypothetical protein	NA	NA	NA	NA
AVQ72220.1\|2744297_2745254_+\|transposase	IS110 family transposase	Q75QL1	Wolbachia_phage	2.9e-31	36.0
AVQ72221.1\|2745449_2745710_+	hypothetical protein	NA	NA	NA	NA
AVQ74323.1\|2745800_2746757_+\|transposase	IS110 family transposase	Q75QL1	Wolbachia_phage	4.5e-32	36.0
AVQ72222.1\|2747094_2748333_-	lipid-A-disaccharide synthase	NA	NA	NA	NA
AVQ72223.1\|2748504_2749665_-	mannose-1-phosphate guanyltransferase	G3MA50	Bacillus_virus	7.9e-15	29.0
AVQ72224.1\|2749851_2750148_-	hypothetical protein	NA	NA	NA	NA
AVQ72225.1\|2750168_2750657_+	CopY family transcriptional regulator	NA	NA	NA	NA
AVQ72226.1\|2750656_2751505_+\|protease	Zn-dependent protease with chaperone function	NA	NA	NA	NA
AVQ72227.1\|2751507_2751975_+	peroxiredoxin	NA	NA	NA	NA
AVQ74324.1\|2752131_2752929_+	30S ribosomal protein S2	NA	NA	NA	NA
AVQ72228.1\|2753045_2753801_+	translation elongation factor Ts	NA	NA	NA	NA
AVQ72229.1\|2754010_2754943_+	diguanylate cyclase response regulator	A0A127AWB9	Bacillus_phage	2.7e-21	37.2
AVQ72230.1\|2754939_2755722_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AVQ72231.1\|2755981_2756518_+	hypothetical protein	NA	NA	NA	NA
AVQ72232.1\|2756572_2758372_-	SLC13 family permease	NA	NA	NA	NA
AVQ72233.1\|2758376_2761157_-	magnesium-transporting ATPase	A0A1J0FA34	Only_Syngen_Nebraska_virus	1.3e-87	32.5
AVQ72234.1\|2761594_2763025_+	15-cis-phytoene desaturase	A0A1B4WGU2	Cucumber_mosaic_virus	3.7e-06	71.9
AVQ72235.1\|2763130_2764063_+	phytoene synthase	NA	NA	NA	NA
AVQ72236.1\|2764126_2764603_-	hypothetical protein	NA	NA	NA	NA
AVQ72237.1\|2764860_2765103_+	hypothetical protein	NA	NA	NA	NA
AVQ72238.1\|2765163_2765856_-	pirin family protein	NA	NA	NA	NA
AVQ72239.1\|2766307_2767126_+	hypothetical protein	NA	NA	NA	NA
AVQ72240.1\|2767342_2767987_-	hypothetical protein	NA	NA	NA	NA
AVQ72241.1\|2767985_2768945_+	enediyne biosynthesis protein UnbU	NA	NA	NA	NA
AVQ72242.1\|2769029_2774990_+	beta keto-acyl synthase	NA	NA	NA	NA
AVQ72243.1\|2775039_2775606_+	hypothetical protein	NA	NA	NA	NA
AVQ72244.1\|2775740_2775974_-	hypothetical protein	NA	NA	NA	NA
AVQ72245.1\|2775997_2776939_-	hypothetical protein	NA	NA	NA	NA
AVQ74325.1\|2777017_2777206_+	hypothetical protein	NA	NA	NA	NA
AVQ72246.1\|2777202_2777616_+	hypothetical protein	NA	NA	NA	NA
AVQ72247.1\|2777628_2778012_-	hypothetical protein	NA	NA	NA	NA
AVQ72248.1\|2778339_2778768_+	4-hydroxybenzoyl-CoA thioesterase	NA	NA	NA	NA
AVQ72249.1\|2778962_2780126_-	ABC transporter permease	NA	NA	NA	NA
AVQ72250.1\|2781697_2782750_+	hypothetical protein	NA	NA	NA	NA
AVQ72251.1\|2782801_2784700_+	RNA-binding protein	NA	NA	NA	NA
AVQ72252.1\|2784870_2784954_+	hypothetical protein	NA	NA	NA	NA
AVQ74326.1\|2784976_2785318_-	hypothetical protein	NA	NA	NA	NA
AVQ72253.1\|2785518_2787180_-	metallophosphoesterase	NA	NA	NA	NA
AVQ72254.1\|2787256_2788999_-	hypothetical protein	W8CYL7	Bacillus_phage	2.7e-43	26.7
AVQ72255.1\|2789322_2789850_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AVQ72256.1\|2789861_2790173_-	hypothetical protein	NA	NA	NA	NA
AVQ72257.1\|2790311_2790881_-\|transposase	transposase	NA	NA	NA	NA
AVQ72258.1\|2790955_2791462_+	hypothetical protein	NA	NA	NA	NA
AVQ72259.1\|2791519_2792518_+	hypothetical protein	NA	NA	NA	NA
AVQ72260.1\|2794547_2794736_-	C4-dicarboxylate ABC transporter	NA	NA	NA	NA
AVQ74327.1\|2794860_2796519_-\|transposase	IS1634 family transposase	NA	NA	NA	NA

DBSCAN-SWA_7

3437993 : 3495640

Bacillus_virus(21.43%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ72822.1\|3437993_3438461_-\|protease	aspartyl protease	NA	NA	NA	NA
AVQ74361.1\|3439204_3440296_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
AVQ72823.1\|3440599_3441229_-	hypothetical protein	NA	NA	NA	NA
AVQ72824.1\|3441473_3443405_+	glycine oxidase ThiO	NA	NA	NA	NA
AVQ74362.1\|3443567_3443906_+	hypothetical protein	NA	NA	NA	NA
AVQ72825.1\|3443960_3445496_-	transporter	NA	NA	NA	NA
AVQ72826.1\|3446240_3447785_-	gamma-glutamyltransferase	NA	NA	NA	NA
AVQ72827.1\|3447932_3448964_-	UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase	NA	NA	NA	NA
AVQ74363.1\|3449163_3450048_-	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
AVQ72828.1\|3450384_3451410_+	daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.3e-24	30.3
AVQ72829.1\|3451492_3452188_+	3-oxoacyl-ACP reductase	NA	NA	NA	NA
AVQ72830.1\|3452256_3452913_+	acyl-phosphate glycerol 3-phosphate acyltransferase	NA	NA	NA	NA
AVQ72831.1\|3452842_3453040_-	hypothetical protein	NA	NA	NA	NA
AVQ72832.1\|3453091_3453592_-	hypothetical protein	NA	NA	NA	NA
AVQ72833.1\|3453569_3453941_-	DNA polymerase subunit beta	NA	NA	NA	NA
AVQ72834.1\|3453967_3454438_-	hypothetical protein	NA	NA	NA	NA
AVQ72835.1\|3454419_3454773_-	signal peptidase	NA	NA	NA	NA
AVQ72836.1\|3454960_3455791_-	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
AVQ72837.1\|3456252_3456705_-	acid phosphatase	NA	NA	NA	NA
AVQ72838.1\|3456722_3457652_-	farnesyl-diphosphate synthase	NA	NA	NA	NA
AVQ72839.1\|3458057_3459455_+	serine/threonine protein kinase	A0A2I2L395	Orpheovirus	2.1e-09	26.3
AVQ72840.1\|3459774_3460350_+	peptide deformylase	E3SLL2	Synechococcus_phage	1.9e-25	45.4
AVQ72841.1\|3460381_3460579_+	hypothetical protein	NA	NA	NA	NA
AVQ72842.1\|3460970_3461288_+	ferredoxin	A0A222YX16	Synechococcus_phage	4.8e-15	43.6
AVQ72843.1\|3461369_3463010_-	CTP synthetase	A0A1J0FA14	Only_Syngen_Nebraska_virus	6.3e-143	49.7
AVQ72844.1\|3463138_3463960_-\|transposase	transposase	G3MB42	Bacillus_virus	5.2e-53	42.5
AVQ72845.1\|3464159_3464387_-\|transposase	transposase	NA	NA	NA	NA
AVQ72846.1\|3464798_3465152_+	hypothetical protein	NA	NA	NA	NA
AVQ72847.1\|3465206_3465977_-	ABC transporter permease	NA	NA	NA	NA
AVQ72848.1\|3465989_3467198_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
AVQ72849.1\|3467202_3467985_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.3e-32	39.2
AVQ72850.1\|3467981_3469097_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
AVQ72851.1\|3469109_3469640_-	hypothetical protein	NA	NA	NA	NA
AVQ72852.1\|3470011_3471379_+	serine/threonine protein kinase	A7XCT1	Tanapox_virus	1.7e-08	25.8
AVQ72853.1\|3471370_3472810_-	lysine decarboxylase	NA	NA	NA	NA
AVQ72854.1\|3472905_3474720_-	long-chain fatty acid--CoA ligase	W8CYL7	Bacillus_phage	2.2e-48	28.6
AVQ72855.1\|3474760_3475837_-	hypothetical protein	NA	NA	NA	NA
AVQ72856.1\|3475871_3476249_-	hypothetical protein	NA	NA	NA	NA
AVQ72857.1\|3476447_3477704_-	histidine kinase	NA	NA	NA	NA
AVQ72858.1\|3478092_3478407_+	hypothetical protein	NA	NA	NA	NA
AVQ72859.1\|3478523_3479993_-	peptidase S8	A0A217EQY2	Bacillus_phage	3.6e-41	43.9
AVQ72860.1\|3483642_3484431_+	DNA-binding response regulator	NA	NA	NA	NA
AVQ72861.1\|3484516_3486412_-	cell division protein FtsH	M4QMW8	Micromonas_pusilla_virus	3.8e-123	45.9
AVQ72862.1\|3486626_3487097_+	ribosome maturation factor RimP	NA	NA	NA	NA
AVQ72863.1\|3487275_3488472_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
AVQ72864.1\|3488468_3488750_+	nucleic acid-binding protein	NA	NA	NA	NA
AVQ72865.1\|3488859_3491919_+	translation initiation factor IF-2	E3T4N3	Cafeteria_roenbergensis_virus	9.0e-26	23.9
AVQ72866.1\|3492100_3492670_+	hypothetical protein	NA	NA	NA	NA
AVQ74364.1\|3492696_3493425_-	carbonic anhydrase	NA	NA	NA	NA
AVQ72867.1\|3493836_3494430_+\|transposase	IS607 family transposase	F9VHY9	Thermus_phage	1.6e-51	58.5
AVQ72868.1\|3494401_3495640_+\|transposase	transposase	G3MB42	Bacillus_virus	9.8e-64	38.2

DBSCAN-SWA_8

3756926 : 3793599

Wolbachia_phage(20.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ73110.1\|3756926_3757613_+\|protease	ATP-dependent Clp protease proteolytic subunit	G3M9Z8	Bacillus_virus	3.2e-24	33.3
AVQ73111.1\|3757648_3758248_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	5.8e-46	52.4
AVQ73112.1\|3758624_3759299_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	1.7e-14	35.5
AVQ73113.1\|3759431_3759887_-	ferredoxin	NA	NA	NA	NA
AVQ73114.1\|3759942_3760245_-	hypothetical protein	NA	NA	NA	NA
AVQ73115.1\|3760369_3761557_-\|transposase	transposase	A0A0R8V9X2	Thermobifida_phage	7.1e-120	59.6
AVQ73116.1\|3761661_3762063_+	hypothetical protein	NA	NA	NA	NA
AVQ73117.1\|3762247_3763723_+	cobyric acid synthase CobQ	NA	NA	NA	NA
AVQ73118.1\|3763732_3763972_+	(2Fe-2S)-binding protein	NA	NA	NA	NA
AVQ73119.1\|3764259_3764877_+	hypothetical protein	NA	NA	NA	NA
AVQ73120.1\|3764977_3765682_-	cytochrome B	NA	NA	NA	NA
AVQ73121.1\|3765727_3766468_+	TIGR00297 family protein	NA	NA	NA	NA
AVQ73122.1\|3766492_3767548_+	amino acid ABC transporter substrate-binding protein	A0A1B1IT51	uncultured_Mediterranean_phage	3.6e-59	39.4
AVQ73123.1\|3767550_3768438_-	lipid kinase	A0A1V0SBJ0	Catovirus	4.0e-11	26.8
AVQ73124.1\|3768753_3769413_+	anion permease	NA	NA	NA	NA
AVQ73125.1\|3769640_3770885_+\|transposase	transposase	Q19ZT4	Mycobacterium_virus	9.5e-67	39.5
AVQ73126.1\|3770914_3771106_-	hypothetical protein	NA	NA	NA	NA
AVQ73127.1\|3771132_3771753_+	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
AVQ73128.1\|3771818_3772061_-	hypothetical protein	NA	NA	NA	NA
AVQ73129.1\|3772121_3772976_-	flagellar assembly protein H	NA	NA	NA	NA
AVQ73130.1\|3773006_3773207_-	aspartate aminotransferase	NA	NA	NA	NA
AVQ73131.1\|3773496_3773736_-	hypothetical protein	NA	NA	NA	NA
AVQ73132.1\|3773726_3774029_-	hypothetical protein	NA	NA	NA	NA
AVQ73133.1\|3774084_3775986_-	glutamine--fructose-6-phosphate aminotransferase	A7IW18	Paramecium_bursaria_Chlorella_virus	8.4e-115	40.0
AVQ73134.1\|3776208_3776415_-	hypothetical protein	NA	NA	NA	NA
AVQ73135.1\|3776940_3777927_-	alcohol dehydrogenase	NA	NA	NA	NA
AVQ73136.1\|3777932_3778427_-	acetyl-CoA carboxylase, biotin carboxyl carrier protein	NA	NA	NA	NA
AVQ73137.1\|3778593_3779151_-	elongation factor P	NA	NA	NA	NA
AVQ73138.1\|3779436_3779754_+	hypothetical protein	NA	NA	NA	NA
AVQ73139.1\|3780058_3780787_-	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
AVQ74377.1\|3781343_3782018_-	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
AVQ73140.1\|3782976_3784545_+	GTP-binding protein	NA	NA	NA	NA
AVQ73141.1\|3784624_3785221_+	phosphohydrolase	NA	NA	NA	NA
AVQ73142.1\|3785276_3785681_+	ribosome silencing factor RsfS	NA	NA	NA	NA
AVQ73143.1\|3785686_3786190_+	hypothetical protein	NA	NA	NA	NA
AVQ73144.1\|3786212_3787166_+	asparaginase	NA	NA	NA	NA
AVQ73145.1\|3787538_3787670_+	addiction module toxin RelE	NA	NA	NA	NA
AVQ73146.1\|3787883_3788666_-	hypothetical protein	NA	NA	NA	NA
AVQ73147.1\|3789163_3790159_-	L-lactate dehydrogenase	NA	NA	NA	NA
AVQ73148.1\|3790395_3790737_+	hypothetical protein	NA	NA	NA	NA
AVQ74378.1\|3790943_3792353_+\|transposase	IS4 family transposase	Q9JMP3	Wolbachia_phage	6.1e-78	36.4
AVQ74379.1\|3792642_3793599_+\|transposase	IS110 family transposase	Q75QL1	Wolbachia_phage	4.5e-32	36.0

DBSCAN-SWA_9

3837018 : 3896336

Streptomyces_phage(25.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ73188.1\|3837018_3838509_-\|protease	site-2 protease family protein	NA	NA	NA	NA
AVQ73189.1\|3838536_3839457_-	N-acetylmuramic acid 6-phosphate etherase	NA	NA	NA	NA
AVQ73190.1\|3839652_3840042_+	50S ribosomal protein L21	NA	NA	NA	NA
AVQ73191.1\|3840076_3840346_+	50S ribosomal protein L27	NA	NA	NA	NA
AVQ73192.1\|3840493_3841426_+	phytanoyl-CoA dioxygenase	NA	NA	NA	NA
AVQ73193.1\|3841639_3841993_-	DUF86 domain-containing protein	NA	NA	NA	NA
AVQ73194.1\|3841982_3842273_-	nucleotidyltransferase	NA	NA	NA	NA
AVQ73195.1\|3842410_3843400_-	acetyl-CoA carboxylase carboxyl transferase subunit alpha	NA	NA	NA	NA
AVQ73196.1\|3843574_3844522_+	spermidine synthase	NA	NA	NA	NA
AVQ73197.1\|3844570_3846853_-	single-stranded-DNA-specific exonuclease RecJ	A0A1W6JL19	Lactococcus_phage	1.7e-29	27.6
AVQ73198.1\|3847130_3847385_-	molybdopterin synthase sulfur carrier subunit	NA	NA	NA	NA
AVQ73199.1\|3847404_3850428_-	ATP-binding cassette family protein	G3MAB6	Bacillus_virus	8.6e-21	31.4
AVQ73200.1\|3850604_3850832_-	hypothetical protein	NA	NA	NA	NA
AVQ73201.1\|3851042_3851381_+	rhodanese-related sulfurtransferase	NA	NA	NA	NA
AVQ73202.1\|3851761_3852838_+	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
AVQ73203.1\|3852824_3853118_-	hypothetical protein	NA	NA	NA	NA
AVQ73204.1\|3853741_3854137_+	hypothetical protein	NA	NA	NA	NA
AVQ74383.1\|3856120_3856882_+\|transposase	IS1 family transposase	NA	NA	NA	NA
AVQ73205.1\|3858911_3859787_+	lipoyl synthase	NA	NA	NA	NA
AVQ73206.1\|3859749_3860343_-	non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family	A0A2H4V8Y9	Ugandan_cassava_brown_streak_virus	1.9e-12	31.7
AVQ73207.1\|3861385_3861829_+	molybdopterin synthase	NA	NA	NA	NA
AVQ73208.1\|3861831_3862911_-	hypothetical protein	NA	NA	NA	NA
AVQ73209.1\|3863171_3864734_-	B12-binding domain-containing radical SAM protein	A0A0M4R1U9	Streptomyces_phage	6.7e-09	23.0
AVQ73210.1\|3865010_3865154_+	high light inducible protein	NA	NA	NA	NA
AVQ73211.1\|3865431_3866754_+	glutamate dehydrogenase	NA	NA	NA	NA
AVQ73212.1\|3866958_3869691_+	carbonate dehydratase	M1IAU8	Acanthocystis_turfacea_Chlorella_virus	2.0e-69	26.6
AVQ73213.1\|3869734_3870769_-	dihydroorotase	NA	NA	NA	NA
AVQ73214.1\|3871354_3873037_+	site-specific DNA-methyltransferase	A0A2L1IZ21	Streptomyces_phage	6.1e-133	44.8
AVQ73215.1\|3873205_3874036_+	hypothetical protein	NA	NA	NA	NA
AVQ73216.1\|3874113_3874668_-	hypothetical protein	NA	NA	NA	NA
AVQ73217.1\|3875072_3876131_+	hypothetical protein	NA	NA	NA	NA
AVQ73218.1\|3876127_3876709_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AVQ73219.1\|3876783_3877227_+	hypothetical protein	NA	NA	NA	NA
AVQ73220.1\|3877764_3880119_+	bile acid beta-glucosidase	NA	NA	NA	NA
AVQ73221.1\|3880452_3882933_+\|protease	CPBP family intramembrane metalloprotease domain-containing protein	NA	NA	NA	NA
AVQ73222.1\|3883014_3883869_+	hypothetical protein	NA	NA	NA	NA
AVQ73223.1\|3883868_3885740_+	hypothetical protein	NA	NA	NA	NA
AVQ73224.1\|3885729_3886827_+	ATPase	NA	NA	NA	NA
AVQ73225.1\|3886835_3889364_+	serine/threonine-protein kinase pkn1	A0A075BSL8	Microcystis_phage	1.0e-75	55.5
AVQ74384.1\|3889564_3890974_-\|transposase	IS4 family transposase	Q9JMP3	Wolbachia_phage	8.0e-78	36.4
AVQ73226.1\|3891355_3891826_-	DUF3368 domain-containing protein	NA	NA	NA	NA
AVQ73227.1\|3891822_3892125_-	hypothetical protein	NA	NA	NA	NA
AVQ73228.1\|3892354_3892705_-	nucleotide-binding protein	NA	NA	NA	NA
AVQ73229.1\|3893137_3893392_-	prevent-host-death protein	NA	NA	NA	NA
AVQ73230.1\|3893488_3893728_-	hypothetical protein	NA	NA	NA	NA
AVQ73231.1\|3893803_3895750_-	low-complexity protein	NA	NA	NA	NA
AVQ73232.1\|3895755_3896040_-	metal-binding protein	NA	NA	NA	NA
AVQ73233.1\|3896042_3896336_-\|protease	Clp protease ClpS	NA	NA	NA	NA

DBSCAN-SWA_10

4401367 : 4431877

Streptococcus_phage(25.0%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVQ73624.1\|4401367_4401841_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
AVQ73625.1\|4402124_4402460_-	hypothetical protein	NA	NA	NA	NA
AVQ73626.1\|4402926_4404144_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
AVQ73627.1\|4404406_4405450_-	DNA (cytosine-5-)-methyltransferase	Q6DMX0	Streptococcus_phage	1.8e-71	46.9
AVQ73628.1\|4406394_4406940_+	hypothetical protein	NA	NA	NA	NA
AVQ73629.1\|4406936_4407908_-	solanesyl diphosphate synthase	NA	NA	NA	NA
AVQ73630.1\|4408328_4409024_+	haloacid dehalogenase	NA	NA	NA	NA
AVQ73631.1\|4409020_4409641_-	molecular chaperone DnaJ	NA	NA	NA	NA
AVQ73632.1\|4409727_4410789_-	complex I intermediate-associated 30 family protein	NA	NA	NA	NA
AVQ74424.1\|4411371_4413699_+	hypothetical protein	NA	NA	NA	NA
AVQ73633.1\|4413793_4413991_-	hypothetical protein	NA	NA	NA	NA
AVQ73634.1\|4417614_4418223_-	hypothetical protein	NA	NA	NA	NA
AVQ73635.1\|4418282_4419383_-\|protease	serine protease	A0A1B1IRH0	uncultured_Mediterranean_phage	1.2e-09	34.2
AVQ73636.1\|4419526_4420021_-	lipoprotein NlpI	NA	NA	NA	NA
AVQ74425.1\|4420510_4421467_-\|transposase	IS110 family transposase	Q75QL1	Wolbachia_phage	4.5e-32	36.0
AVQ73637.1\|4421557_4421827_-	hypothetical protein	NA	NA	NA	NA
AVQ73638.1\|4424700_4424979_-	hypothetical protein	NA	NA	NA	NA
AVQ73639.1\|4424975_4425269_-	DNA polymerase subunit beta	NA	NA	NA	NA
AVQ73640.1\|4425547_4425892_-	hypothetical protein	NA	NA	NA	NA
AVQ73641.1\|4426025_4427240_-\|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	1.1e-24	26.1
AVQ73642.1\|4427402_4427678_-	hypothetical protein	NA	NA	NA	NA
AVQ73643.1\|4429340_4429790_+	hypothetical protein	NA	NA	NA	NA
AVQ74426.1\|4429852_4430479_+\|transposase	IS630 family transposase	NA	NA	NA	NA
AVQ73644.1\|4430719_4431877_-\|transposase	IS630 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP020664

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection