CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
CP028178	Klebsiella pneumoniae strain CFSAN054111 plasmid pGMI16-006_2, complete sequence	0 crisprs	NA	2
CP028179	Klebsiella pneumoniae strain CFSAN054111 plasmid pGMI16-006_3, complete sequence	0 crisprs	NA	2
CP028176	Klebsiella pneumoniae strain CFSAN054111 chromosome, complete genome	0 crisprs	cas3,DinG,WYL,DEDDh,RT,csa3,cas8e,cse2gr11,cas6e,cas7,cas5,cas1,cas2	5
CP028177	Klebsiella pneumoniae strain CFSAN054111 plasmid pGMI16-006_1, complete sequence	0 crisprs	NA	2

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

5679 : 37386

Salmonella_phage(27.27%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVS24349.1\|5679_8652_-\|transposase	Tn3-like element ISPa38 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.1
AVS24350.1\|8726_9017_+	nucleotidyltransferase	NA	NA	NA	NA
AVS24351.1\|9013_9415_+	DUF86 domain-containing protein	NA	NA	NA	NA
AVS24352.1\|9404_9761_+	cupin domain-containing protein	NA	NA	NA	NA
AVS24353.1\|10015_10330_+	hypothetical protein	NA	NA	NA	NA
AVS24354.1\|10756_11938_-	Na+/H+ antiporter NhaA	A0A2H4J5W3	uncultured_Caudovirales_phage	1.9e-120	64.2
AVS24355.1\|12597_13203_-	DNA resolvase	A0A1S5Y2X8	uncultured_archaeal_virus	5.5e-20	35.3
AVS24356.1\|13426_14287_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
AVS24357.1\|14986_15811_-	oxacillin-hydrolyzing class D beta-lactamase OXA-9	NA	NA	NA	NA
AVS24358.1\|15870_16659_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA1	NA	NA	NA	NA
AVS24437.1\|16728_17283_-	AAC(6')-Ib family aminoglycoside 6'-N-acetyltransferase	NA	NA	NA	NA
AVS24359.1\|17516_18074_-	recombinase	Q1MVP4	Enterobacteria_phage	2.0e-93	98.4
AVS24360.1\|18637_19900_+\|transposase	IS1380 family transposase ISEc9	A0A1B0VDR3	Salmonella_phage	1.3e-39	100.0
AVS24361.1\|20155_21031_+	class A extended-spectrum beta-lactamase CTX-M-15	A0A1B0VBP7	Salmonella_phage	1.1e-125	82.4
AVS24362.1\|21077_21410_-	cupin fold metalloprotein, WbuC family	NA	NA	NA	NA
AVS24363.1\|25671_26328_+	quinolone resistance pentapeptide repeat protein QnrS1	NA	NA	NA	NA
AVS24364.1\|27107_28499_-\|transposase	ISKra4 family transposase ISKpn19	NA	NA	NA	NA
AVS24365.1\|28535_29108_-	recombinase family protein	M9Q1K0	Clostridium_phage	3.4e-19	39.4
AVS24366.1\|29244_29835_-	plasmid pRiA4b ORF-3 family protein	NA	NA	NA	NA
AVS24367.1\|30205_30985_+	APH(3')-VI family aminoglycoside O-phosphotransferase	E4ZFP6	Streptococcus_phage	6.9e-31	34.7
AVS24368.1\|31136_32075_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	4.4e-48	37.4
AVS24369.1\|32171_33203_+\|transposase	IS630 family transposase	NA	NA	NA	NA
AVS24370.1\|33417_34230_+	subclass B1 metallo-beta-lactamase NDM-1	NA	NA	NA	NA
AVS24371.1\|34233_34599_+	bleomycin binding protein Ble-MBL	NA	NA	NA	NA
AVS24372.1\|34603_35242_+	phosphoribosylanthranilate isomerase	NA	NA	NA	NA
AVS24373.1\|35252_36284_-	twin-arginine translocation (TAT) pathway signal sequence domain protein	NA	NA	NA	NA
AVS24374.1\|36288_36618_-	divalent-cation tolerance protein CutA	NA	NA	NA	NA
AVS24375.1\|36681_37386_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	9.9e-138	99.6

DBSCAN-SWA_2

86432 : 97668

Stx2-converting_phage(30.0%)

integrase,transposase

attL 86883:86895|attR 98404:98416

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVS24442.1\|86432_87110_-	resolvase	I3WFA4	Macacine_betaherpesvirus	1.1e-21	50.5
86883:86895	attL	NA	NA	NA	NA
AVS24424.1\|87795_88044_-	XRE family transcriptional regulator	A0A248SLB9	Klebsiella_phage	2.1e-10	50.7
AVS24425.1\|89487_89919_+	peptidase	A0A1W6JNS2	Morganella_phage	2.1e-29	53.3
AVS24426.1\|89918_91190_+	translesion error-prone DNA polymerase V subunit UmuC	F1C5A5	Cronobacter_phage	2.9e-151	63.3
AVS24427.1\|91601_92477_+	replication initiation protein	Q71TL8	Escherichia_phage	5.6e-82	56.4
AVS24428.1\|92769_93147_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	7.9e-57	90.5
AVS24429.1\|93143_93491_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZDM8	Stx2-converting_phage	4.1e-60	96.5
AVS24430.1\|93540_95079_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	6.1e-273	91.8
AVS24431.1\|95508_96135_+	cobyrinic acid ac-diamide synthase	A0A222YXS3	Escherichia_phage	2.2e-40	43.6
AVS24432.1\|96254_96434_+	Par-like protein	NA	NA	NA	NA
AVS24433.1\|96873_97668_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	1.2e-51	87.8
98404:98416	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP028176

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

15822 : 62725

Klebsiella_phage(23.4%)

terminase,integrase,holin,tail

attL 5914:5929|attR 60031:60046

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
5914:5929	attL	NA	NA	NA	NA
AVS19225.1\|15822_18024_-	hypothetical protein	B5TAB2	Burkholderia_phage	4.4e-99	38.0
AVS19226.1\|18099_21174_-	kinase	A0A286S259	Klebsiella_phage	0.0e+00	96.7
AVS19227.1\|21170_21551_-	nitrite transporter	A0A286S2A6	Klebsiella_phage	2.4e-69	94.4
AVS19228.1\|21560_22043_-	DUF1833 domain-containing protein	A0A286S2B1	Klebsiella_phage	1.1e-82	96.2
AVS19229.1\|22223_22688_-	hypothetical protein	A0A286S298	Klebsiella_phage	3.0e-58	68.4
AVS19230.1\|22687_25588_-\|tail	phage tail protein	A0A2H4J107	uncultured_Caudovirales_phage	5.2e-100	32.0
AVS23979.1\|25679_26153_-	zinc ribbon domain-containing protein	S4TR42	Salmonella_phage	4.6e-22	57.4
AVS19231.1\|26266_26434_-	hypothetical protein	NA	NA	NA	NA
AVS19232.1\|26601_27084_-	hypothetical protein	NA	NA	NA	NA
AVS19233.1\|27137_28310_-	Ig domain-containing protein	A0A0D4DBN5	Acinetobacter_phage	1.2e-23	27.0
AVS19234.1\|28333_28726_-	electron transfer flavoprotein subunit beta	NA	NA	NA	NA
AVS19235.1\|28722_29274_-	hypothetical protein	G8C7Q1	Escherichia_phage	7.8e-29	39.9
AVS19236.1\|29275_29659_-	glutamate 5-kinase	A0A0S2SYG4	Pseudomonas_phage	7.1e-21	45.2
AVS19237.1\|29645_29879_-	hypothetical protein	A0A2H4J0Y9	uncultured_Caudovirales_phage	5.8e-10	47.1
AVS19238.1\|29888_30143_-	hypothetical protein	J9Q7U0	Salmonella_phage	8.0e-21	52.4
AVS19239.1\|30144_30540_-	protein singed	A0A0S2SYB7	Pseudomonas_phage	3.3e-13	43.3
AVS19240.1\|30861_31815_-	hypothetical protein	A0A1B0VMF8	Pseudomonas_phage	2.5e-131	74.0
AVS19241.1\|31825_32611_-	hypothetical protein	A0A1B0VMG1	Pseudomonas_phage	1.0e-66	63.9
AVS19242.1\|32695_33808_-	hypothetical protein	I6PD76	Cronobacter_phage	4.8e-110	55.2
AVS19243.1\|33791_35192_-	DUF4055 domain-containing protein	A0A1B0VMH0	Pseudomonas_phage	9.2e-127	53.5
AVS19244.1\|35191_36499_-\|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	5.2e-148	58.7
AVS19245.1\|36476_37481_-\|terminase	terminase small subunit	Q5QF76	Pseudomonas_virus	1.5e-38	45.5
AVS19246.1\|38029_38215_-	hypothetical protein	NA	NA	NA	NA
AVS19247.1\|38343_38589_-	DUF2560 domain-containing protein	A0A286N2R1	Klebsiella_phage	4.6e-34	96.3
AVS19248.1\|39402_39597_-	hypothetical protein	A0A286SGR9	Klebsiella_phage	1.4e-25	89.1
AVS19249.1\|39547_39823_-	hypothetical protein	A0A286N2Q8	Klebsiella_phage	2.2e-08	72.5
AVS19250.1\|39819_40164_-	hypothetical protein	A0A286N2Q7	Klebsiella_phage	2.0e-38	80.7
AVS19251.1\|40160_40700_-	hypothetical protein	A0A286N2Q6	Klebsiella_phage	2.3e-102	100.0
AVS19252.1\|40696_41008_-\|holin	holin	A0A286N2Q5	Klebsiella_phage	1.6e-47	98.0
AVS19253.1\|41609_42056_+	hypothetical protein	NA	NA	NA	NA
AVS23980.1\|41961_42219_-	hypothetical protein	A0A286N2Q3	Klebsiella_phage	2.8e-42	98.8
AVS19254.1\|42372_43155_-	antitermination protein	F1C595	Cronobacter_phage	2.9e-114	79.1
AVS19255.1\|43151_43520_-	RusA family crossover junction endodeoxyribonuclease	G8C7V6	Escherichia_phage	3.5e-41	63.8
AVS19256.1\|43516_43813_-	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	1.7e-35	71.9
AVS19257.1\|43815_44022_-	hypothetical protein	H6WRY8	Salmonella_phage	1.4e-23	72.7
AVS19258.1\|44021_44621_-	DUF1367 domain-containing protein	K7PKS6	Enterobacteria_phage	1.7e-90	79.9
AVS19259.1\|44678_44900_-	hypothetical protein	NA	NA	NA	NA
AVS19260.1\|44977_45211_-	DNA damage-inducible protein I	K7PM44	Enterobacteria_phage	7.0e-24	67.5
AVS19261.1\|45813_46656_-	hypothetical protein	NA	NA	NA	NA
AVS23981.1\|46645_47689_-	DGQHR domain-containing protein	NA	NA	NA	NA
AVS19262.1\|47942_48179_-	hypothetical protein	A0A2R2Z309	Escherichia_phage	2.4e-32	92.1
AVS19263.1\|48171_48375_-	hypothetical protein	A0A2R2Z313	Escherichia_phage	3.7e-29	92.5
AVS19264.1\|48371_48740_-	DUF977 domain-containing protein	H6WRX9	Salmonella_phage	6.4e-11	44.3
AVS19265.1\|48747_49497_-	DNA replication protein DnaC	H6WRX8	Salmonella_phage	3.0e-116	80.3
AVS23982.1\|49499_50339_-	hypothetical protein	Q8HA96	Salmonella_phage	2.3e-24	53.1
AVS19266.1\|50404_51199_-	hypothetical protein	C7BGF1	Burkholderia_phage	6.3e-64	51.3
AVS19267.1\|51327_51864_-	hypothetical protein	K7PJT7	Enterobacteria_phage	4.4e-61	69.5
AVS19268.1\|51866_52130_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AVS19269.1\|52226_52583_+	hypothetical protein	NA	NA	NA	NA
AVS19270.1\|52809_53118_+	hypothetical protein	G8C7T6	Escherichia_phage	1.7e-25	62.2
AVS19271.1\|53209_53308_+	hypothetical protein	NA	NA	NA	NA
AVS19272.1\|53414_53606_+	DUF1482 domain-containing protein	NA	NA	NA	NA
AVS19273.1\|53907_57045_+	exodeoxyribonuclease	H6WRX1	Salmonella_phage	2.7e-291	56.7
AVS19274.1\|57057_58167_+	enterohemolysin	H6WRX0	Salmonella_phage	1.0e-184	86.7
AVS19275.1\|58207_58447_+	DUF4060 domain-containing protein	M9P0E0	Enterobacteria_phage	6.8e-22	67.5
AVS19276.1\|58456_58771_+	hypothetical protein	K7PM28	Enterobacteria_phage	1.6e-10	50.8
AVS19277.1\|58667_59855_-\|integrase	site-specific integrase	K7PGY1	Enterobacteria_phage	4.2e-120	52.2
AVS19278.1\|60031_60922_+	peptide ABC transporter permease SapC	NA	NA	NA	NA
60031:60046	attR	NA	NA	NA	NA
AVS19279.1\|60921_61914_+	peptide ABC transporter ATP-binding protein SapD	G9BWD6	Planktothrix_phage	3.0e-07	27.2
AVS19280.1\|61915_62725_+	peptide ABC transporter ATP-binding protein SapF	A0A2H4PQG7	Staphylococcus_phage	2.1e-14	28.9

DBSCAN-SWA_2

181114 : 226785

Enterobacteria_phage(54.29%)

integrase,portal,plate,capsid,tail,tRNA,terminase

attL 186338:186359|attR 223047:223068

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVS19394.1\|181114_181615_+\|tRNA	YbaK/prolyl-tRNA synthetase associated domain-containing protein	NA	NA	NA	NA
AVS19395.1\|181731_182178_+	DUF441 domain-containing protein	NA	NA	NA	NA
AVS23986.1\|182161_182953_-	AraC family transcriptional regulator	NA	NA	NA	NA
AVS19396.1\|183054_184239_+	cyanate MFS transporter	NA	NA	NA	NA
AVS19397.1\|184270_184963_-	hypothetical protein	NA	NA	NA	NA
AVS19398.1\|185108_185618_+	DUF523 domain-containing protein	NA	NA	NA	NA
AVS19399.1\|185604_185961_+	DUF488 domain-containing protein	NA	NA	NA	NA
AVS19400.1\|185950_186190_-	DUF333 domain-containing protein	NA	NA	NA	NA
186338:186359	attL	NA	NA	NA	NA
AVS19401.1\|186454_186706_-	hypothetical protein	A0A2I8TV89	Erwinia_phage	3.4e-08	49.2
AVS19402.1\|186749_187889_-	phage late control D family protein	B9A7A9	Serratia_phage	3.0e-144	70.5
AVS19403.1\|188043_189216_+\|tail	phage tail sheath family protein	A0A0A7NV69	Enterobacteria_phage	1.1e-157	70.5
AVS19404.1\|189215_189731_+\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	2.2e-57	61.2
AVS19405.1\|189776_190094_+\|tail	phage tail protein	B9A7B2	Serratia_phage	1.0e-17	54.8
AVS23987.1\|190093_190252_+\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	3.5e-11	63.3
AVS19406.1\|190238_193214_+\|tail	phage tail tape measure protein	A0A0A7NRZ9	Enterobacteria_phage	1.8e-220	46.6
AVS19407.1\|193229_193721_+\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	2.1e-54	62.7
AVS19408.1\|193965_195324_+	hypothetical protein	A0A1W6JNS5	Morganella_phage	7.5e-49	28.7
AVS19409.1\|195477_196575_-\|tail	phage tail protein	G4KKN6	Yersinia_phage	5.2e-08	47.8
AVS19410.1\|196574_196787_-	hypothetical protein	NA	NA	NA	NA
AVS19411.1\|196783_199810_-\|tail	phage tail protein I	D5LGZ2	Escherichia_phage	6.4e-24	40.7
AVS19412.1\|199799_200723_-\|plate	baseplate assembly protein	A0A0A7NPY5	Enterobacteria_phage	6.9e-54	44.6
AVS19413.1\|200724_201075_-\|plate	baseplate assembly protein	A0A0A7NQ90	Enterobacteria_phage	9.3e-28	54.8
AVS19414.1\|201071_201659_-\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	6.9e-60	60.5
AVS19415.1\|201655_202291_-	phage virion morphogenesis protein	A0A0A7NV60	Enterobacteria_phage	4.6e-57	51.9
AVS19416.1\|202287_202755_-\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	4.5e-46	58.8
AVS23988.1\|202936_203266_-	DUF2570 domain-containing protein	NA	NA	NA	NA
AVS19417.1\|203277_203823_-	lysozyme	Q1I0Z1	Pasteurella_virus	9.7e-32	44.1
AVS19418.1\|203819_204104_-\|tail	phage tail protein	NA	NA	NA	NA
AVS19419.1\|204094_204295_-\|tail	phage tail protein	A0A0A7NV57	Enterobacteria_phage	1.6e-16	63.1
AVS19420.1\|204294_204810_-\|capsid	capsid assembly protein	A0A0A7NPU2	Enterobacteria_phage	3.1e-40	49.4
AVS19421.1\|204914_205781_-\|terminase	terminase	A0A0A7NPX9	Enterobacteria_phage	8.4e-70	57.3
AVS19422.1\|205830_206865_-\|capsid	phage major capsid protein, P2 family	A0A0M3ULA3	Salmonella_phage	8.1e-96	50.0
AVS19423.1\|206875_207715_-\|capsid	phage capsid protein	A0A0A7NRY7	Enterobacteria_phage	1.6e-94	65.9
AVS19424.1\|207871_209599_+	oxidoreductase	A0A0A7NV54	Enterobacteria_phage	6.9e-233	68.1
AVS19425.1\|209592_210654_+\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	1.0e-141	68.4
AVS19426.1\|211130_211883_-	hypothetical protein	NA	NA	NA	NA
AVS19427.1\|211975_212200_-	hypothetical protein	NA	NA	NA	NA
AVS23989.1\|212804_213812_-	hypothetical protein	NA	NA	NA	NA
AVS19428.1\|213804_215751_-	DUF3696 domain-containing protein	Q2P9X8	Enterobacteria_phage	3.4e-18	39.6
AVS19429.1\|216008_218156_-	replication endonuclease	A0A1S6L028	Salmonella_phage	2.4e-243	63.6
AVS19430.1\|218193_219129_-	DNA adenine methylase	A0A0M4QWR0	Salmonella_phage	1.9e-83	55.9
AVS23990.1\|219125_219353_-	hypothetical protein	A0A286S1P6	Klebsiella_phage	1.9e-05	41.0
AVS19431.1\|219361_219928_-	3'-5' exoribonuclease	D4HTX2	Vibrio_phage	9.5e-14	33.2
AVS19432.1\|219924_220149_-	hypothetical protein	NA	NA	NA	NA
AVS19433.1\|220226_220490_-	hypothetical protein	NA	NA	NA	NA
AVS19434.1\|220505_220883_-	hypothetical protein	NA	NA	NA	NA
AVS19435.1\|220898_221117_-	DUF4761 domain-containing protein	A0A0M5M1I3	Salmonella_phage	3.6e-06	49.1
AVS19436.1\|221137_221416_-	hypothetical protein	Q1JS60	Enterobacteria_phage	6.2e-43	88.9
AVS19437.1\|221536_221836_+	XRE family transcriptional regulator	Q1JS61	Enterobacteria_phage	6.5e-38	77.8
AVS19438.1\|221951_222935_+\|integrase	integrase	Q83VS6	Escherichia_phage	6.4e-151	80.1
AVS19439.1\|223199_224213_+	sensor domain-containing diguanylate cyclase	A0A127AWB9	Bacillus_phage	1.9e-12	29.0
223047:223068	attR	NA	NA	NA	NA
AVS19440.1\|224270_224372_+	hypothetical protein	NA	NA	NA	NA
AVS23991.1\|224371_224446_+	hypothetical protein	NA	NA	NA	NA
AVS19441.1\|224563_224689_+	hypothetical protein	NA	NA	NA	NA
AVS19442.1\|224748_225012_-	DUF2534 domain-containing protein	NA	NA	NA	NA
AVS19443.1\|225142_225781_-	leucine efflux protein	NA	NA	NA	NA
AVS19444.1\|225870_226785_-	kdo(2)-lipid IV(A) palmitoleoyltransferase	A0A1W6JP29	Morganella_phage	3.2e-72	50.0

DBSCAN-SWA_3

506784 : 516247

Brazilian_cedratvirus(16.67%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVS19690.1\|506784_508506_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	2.0e-14	34.3
AVS19691.1\|508550_509252_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
AVS19692.1\|509605_509824_+	translation initiation factor IF-1	NA	NA	NA	NA
AVS19693.1\|509943_512223_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.6e-165	42.0
AVS19694.1\|512253_512571_-\|protease	ATP-dependent Clp protease adaptor ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
AVS19695.1\|512896_513118_+	cold shock domain protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
AVS19696.1\|513072_513255_-	hypothetical protein	NA	NA	NA	NA
AVS19697.1\|513194_515135_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	1.9e-37	40.5
AVS19698.1\|515131_516247_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7

DBSCAN-SWA_4

4994911 : 5005798

Escherichia_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVS23731.1\|4994911_4998019_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	59.6
AVS23732.1\|4998073_4999339_+	MFS transporter	NA	NA	NA	NA
AVS23733.1\|4999369_5000458_-	chromosome segregation protein SMC	A0A077SLJ9	Escherichia_phage	3.0e-210	99.7
AVS23734.1\|5000544_5000805_-	hypothetical protein	A0A077SK33	Escherichia_phage	5.4e-41	98.8
AVS23735.1\|5001102_5001963_+	class A beta-lactamase SHV-28	A0A077SL40	Escherichia_phage	1.7e-155	99.3
AVS23736.1\|5001983_5002745_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
AVS23737.1\|5003005_5003908_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	2.6e-159	99.7
AVS23738.1\|5003919_5005185_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	1.1e-232	99.3
AVS23739.1\|5005177_5005798_+	aldolase	A0A077SK32	Escherichia_phage	8.0e-115	100.0

DBSCAN-SWA_5

5173268 : 5233630

Escherichia_phage(28.57%)

protease,plate,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVS23892.1\|5173268_5174204_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	3.5e-138	93.0
AVS23893.1\|5174249_5175623_-	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	8.6e-53	32.3
AVS23894.1\|5175637_5175832_-	hypothetical protein	NA	NA	NA	NA
AVS23895.1\|5176148_5177132_-	zinc transporter ZntB	NA	NA	NA	NA
AVS24200.1\|5177410_5178154_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.7e-15	30.1
AVS23896.1\|5178170_5179235_+	oxidoreductase	NA	NA	NA	NA
AVS23897.1\|5179471_5179666_+	hypothetical protein	NA	NA	NA	NA
AVS23898.1\|5179778_5180528_-	hypothetical protein	NA	NA	NA	NA
AVS23899.1\|5180778_5182158_-	aromatic amino acid transporter AroP	NA	NA	NA	NA
AVS23900.1\|5182492_5182972_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
AVS23901.1\|5183223_5183838_+	YitT family protein	NA	NA	NA	NA
AVS23902.1\|5183876_5185076_+	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
AVS23903.1\|5185104_5185773_-	ABC transporter permease	NA	NA	NA	NA
AVS23904.1\|5185765_5186779_-	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-29	39.1
AVS23905.1\|5186787_5187594_-	methionine-binding protein	NA	NA	NA	NA
AVS23906.1\|5187814_5188990_+	aspartate aminotransferase	NA	NA	NA	NA
AVS23907.1\|5189034_5190069_-	NADP-dependent oxidoreductase	NA	NA	NA	NA
AVS23908.1\|5190157_5190706_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AVS23909.1\|5190762_5191674_-	NmrA/HSCARG family protein	NA	NA	NA	NA
AVS23910.1\|5191666_5192533_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
AVS23911.1\|5192623_5193547_+	LysR family transcriptional regulator	NA	NA	NA	NA
AVS24201.1\|5193566_5194472_-	LysR family transcriptional regulator	NA	NA	NA	NA
AVS23912.1\|5194612_5195542_+	aromatic alcohol reductase	NA	NA	NA	NA
AVS23913.1\|5195567_5195774_+	DUF1471 domain-containing protein	NA	NA	NA	NA
AVS23914.1\|5195824_5196703_-	AraC family transcriptional regulator	NA	NA	NA	NA
AVS23915.1\|5196861_5197617_+	KR domain-containing protein	NA	NA	NA	NA
AVS23916.1\|5197621_5198215_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AVS23917.1\|5198288_5199002_+	oxidoreductase	NA	NA	NA	NA
AVS23918.1\|5199068_5199563_-	hypothetical protein	NA	NA	NA	NA
AVS23919.1\|5199690_5200233_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
AVS23920.1\|5200210_5201296_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
AVS23921.1\|5201259_5203014_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
AVS23922.1\|5203090_5203561_-	hypothetical protein	NA	NA	NA	NA
AVS23923.1\|5204644_5206243_-	type VI secretion system protein TssA	NA	NA	NA	NA
AVS23924.1\|5206239_5209698_-	type VI secretion protein VasK	NA	NA	NA	NA
AVS23925.1\|5209694_5210903_-	hypothetical protein	NA	NA	NA	NA
AVS23926.1\|5212349_5213448_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	9.7e-47	41.0
AVS23927.1\|5213640_5214162_-	hypothetical protein	NA	NA	NA	NA
AVS23928.1\|5214341_5215109_-	hypothetical protein	NA	NA	NA	NA
AVS23929.1\|5215095_5217114_-	M23 family peptidase	NA	NA	NA	NA
AVS23930.1\|5217302_5218334_+\|transposase	IS630-like element ISEc33 family transposase	NA	NA	NA	NA
AVS23931.1\|5218349_5218667_-	hypothetical protein	NA	NA	NA	NA
AVS24202.1\|5219061_5219337_-	hypothetical protein	NA	NA	NA	NA
AVS23932.1\|5219470_5220682_-	hypothetical protein	NA	NA	NA	NA
AVS23933.1\|5220674_5223194_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	2.3e-19	32.6
AVS23934.1\|5223186_5225841_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	5.9e-98	33.4
AVS23935.1\|5226105_5226597_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
AVS23936.1\|5226601_5228308_-	OmpA family protein	NA	NA	NA	NA
AVS23937.1\|5228304_5228994_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
AVS24203.1\|5228990_5230331_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
AVS23938.1\|5230343_5231888_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
AVS23939.1\|5231930_5232422_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
AVS23940.1\|5233063_5233630_+\|protease	protease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP028179

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

5604 : 15453

Salmonella_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVS24448.1\|5604_7074_-	HNH endonuclease	G0X580	Salmonella_phage	5.5e-21	51.3
AVS24449.1\|7830_8400_-	recombinase family protein	E5FFF9	Burkholderia_phage	5.2e-36	43.2
AVS24484.1\|8539_8821_-\|transposase	transposase	NA	NA	NA	NA
AVS24450.1\|8856_9561_+\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AVS24451.1\|9900_12867_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	72.9
AVS24452.1\|12945_13950_+\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
AVS24453.1\|14131_14308_-	DUF4102 domain-containing protein	T1S9J3	Salmonella_phage	1.0e-06	68.6
AVS24454.1\|14637_15453_+	sulfonamide-resistant dihydropteroate synthase Sul2	A0A0B5J4J5	Pandoravirus	5.9e-09	27.6

DBSCAN-SWA_2

19464 : 34858

Escherichia_phage(50.0%)

transposase,integrase

attL 23573:23586|attR 35975:35988

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVS24461.1\|19464_20169_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AVS24485.1\|20193_20706_+	restriction endonuclease	NA	NA	NA	NA
AVS24462.1\|20710_20917_+	hypothetical protein	NA	NA	NA	NA
AVS24463.1\|21298_22732_+	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	7.0e-106	50.6
AVS24464.1\|22765_23974_-	restriction endonuclease	E5E3X4	Burkholderia_phage	1.2e-34	42.5
23573:23586	attL	NA	NA	NA	NA
AVS24465.1\|23986_24199_-	resolvase	NA	NA	NA	NA
AVS24466.1\|24240_25005_-\|transposase	IS6 family transposase IS6100	A0A077SL39	Escherichia_phage	4.3e-86	65.7
AVS24467.1\|25147_25414_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
AVS24468.1\|25634_26117_-	trimethoprim-resistant dihydrofolate reductase DfrA14	G3MBI7	Bacillus_virus	6.6e-16	28.9
AVS24469.1\|26263_27277_+\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
AVS24470.1\|27336_28041_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AVS24471.1\|28147_28831_+	DNA polymerase IV	F1C5A5	Cronobacter_phage	3.5e-79	64.7
AVS24472.1\|28912_29890_-	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	2.6e-88	54.4
AVS24473.1\|29886_31092_-	ParA family protein	A0A077SL49	Escherichia_phage	2.4e-163	69.6
AVS24474.1\|31506_31776_+	hypothetical protein	NA	NA	NA	NA
AVS24475.1\|31808_32006_-	hypothetical protein	NA	NA	NA	NA
AVS24476.1\|32132_32999_-	RepB family plasmid replication initiator protein	A0A222YYK1	Escherichia_phage	1.5e-23	31.1
AVS24477.1\|33766_34024_+	hypothetical protein	NA	NA	NA	NA
AVS24478.1\|34081_34858_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	6.4e-53	92.9
35975:35988	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. CP028177

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

11440 : 23532

Escherichia_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVS24223.1\|11440_12142_-	DNA methylase	A0A2I7RE86	Vibrio_phage	7.1e-27	36.7
AVS24224.1\|12578_12809_-	hypothetical protein	NA	NA	NA	NA
AVS24225.1\|12869_13541_-	Mediator of plasmid stability	NA	NA	NA	NA
AVS24226.1\|13543_14515_-	StbA family protein	A0A222YXF2	Escherichia_phage	1.1e-73	46.8
AVS24227.1\|14746_15178_+	peptidase	A0A1W6JNS2	Morganella_phage	1.0e-28	52.5
AVS24228.1\|15177_16449_+	translesion error-prone DNA polymerase V subunit UmuC	F1C5A5	Cronobacter_phage	3.6e-154	63.7
AVS24229.1\|16849_17746_+	replication initiation protein	Q71TL8	Escherichia_phage	3.3e-69	53.8
AVS24230.1\|18067_19273_+	ParA family protein	Q1MVJ3	Enterobacteria_phage	7.3e-205	89.0
AVS24231.1\|19269_20244_+	ParB/RepB/Spo0J family partition protein	Q1MVJ4	Enterobacteria_phage	1.4e-105	62.3
AVS24232.1\|20415_20601_+	hypothetical protein	NA	NA	NA	NA
AVS24233.1\|20620_20953_+	hypothetical protein	NA	NA	NA	NA
AVS24234.1\|21177_21393_+	hypothetical protein	NA	NA	NA	NA
AVS24235.1\|21504_23532_+	SAM-dependent DNA methyltransferase	A0A220A2U5	Liberibacter_phage	2.1e-26	26.6

DBSCAN-SWA_2

28107 : 59697

Enterobacteria_phage(44.44%)

protease,integrase,transposase

attL 21749:21764|attR 40284:40299

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
21749:21764	attL	NA	NA	NA	NA
AVS24238.1\|28107_29376_+\|transposase	ISL3 family transposase ISKpn25	Q6V7R1	Burkholderia_virus	5.2e-60	34.7
AVS24239.1\|29495_29969_+	YkgJ family cysteine cluster protein	NA	NA	NA	NA
AVS24240.1\|30133_30328_+	hypothetical protein	NA	NA	NA	NA
AVS24241.1\|31182_31965_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	4.6e-51	90.2
AVS24242.1\|31964_32297_-	hypothetical protein	NA	NA	NA	NA
AVS24243.1\|32303_32660_-	hypothetical protein	NA	NA	NA	NA
AVS24244.1\|32727_33057_-	hypothetical protein	NA	NA	NA	NA
AVS24245.1\|33084_33393_-	hypothetical protein	NA	NA	NA	NA
AVS24246.1\|33438_33645_-	hypothetical protein	NA	NA	NA	NA
AVS24338.1\|33879_34314_-	hypothetical protein	NA	NA	NA	NA
AVS24247.1\|34297_34528_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
AVS24248.1\|34524_34941_+	VapC toxin family PIN domain ribonuclease	NA	NA	NA	NA
AVS24249.1\|36517_37795_+	colicin V secretion protein CvaA	NA	NA	NA	NA
AVS24250.1\|37784_39893_+	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	2.4e-38	27.3
AVS24251.1\|39892_40528_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
40284:40299	attR	NA	NA	NA	NA
AVS24252.1\|40635_40980_-	hypothetical protein	NA	NA	NA	NA
AVS24253.1\|41173_41452_-	hypothetical protein	NA	NA	NA	NA
AVS24254.1\|41546_41810_+	hypothetical protein	NA	NA	NA	NA
AVS24255.1\|41874_42579_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AVS24256.1\|42590_43247_-	TetR family transcriptional regulator	NA	NA	NA	NA
AVS24257.1\|43342_44527_+	tetracycline efflux MFS transporter Tet(D)	NA	NA	NA	NA
AVS24258.1\|44621_44912_+	alcohol dehydrogenase	E3SJ82	Synechococcus_phage	4.8e-06	40.6
AVS24259.1\|45006_45867_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
AVS24260.1\|46687_48058_-\|transposase	IS1182 family transposase ISCfr1	NA	NA	NA	NA
AVS24261.1\|48172_49309_-	DUF3883 domain-containing protein	NA	NA	NA	NA
AVS24262.1\|49359_49605_-	hypothetical protein	NA	NA	NA	NA
AVS24263.1\|49610_49802_+	hypothetical protein	NA	NA	NA	NA
AVS24264.1\|50283_50826_-	tunicamycin resistance protein	NA	NA	NA	NA
AVS24265.1\|50838_51699_-	aminoglycoside N-acetyltransferase AAC(3)-IId	NA	NA	NA	NA
AVS24266.1\|51880_52741_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
AVS24267.1\|54324_55113_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA1	NA	NA	NA	NA
AVS24339.1\|55182_55737_-	AAC(6')-Ib family aminoglycoside 6'-N-acetyltransferase	NA	NA	NA	NA
AVS24268.1\|55970_56528_-	recombinase	Q1MVP4	Enterobacteria_phage	2.0e-93	98.4
AVS24269.1\|56691_59697_+\|transposase	Tn3-like element Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	99.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP028178

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP028176

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. CP028179

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

4. CP028177

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection