CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP025221	Listeria monocytogenes strain PIR00543 chromosome, complete genome	3 crisprs	DinG,cas3,WYL,casR,DEDDh,RT,csa3,csn2,cas2,cas1,cas9	3	14	7	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP025221_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025221_3

543382-543668

Orphan

I-A

Consensus_repeat	Method
GTTTTAGTTACTTATTGTGAAATGTAAAT	PILER-CR
GTTTTAGTTACTTATTGTGAAATGTAAAT	CRT
TTTTAGTTACTTATTGTGAAATGTAAAT	CRISPRCasFinder

4 spacers

The CRISPR arrays of CP025221_3

>merge|CP025221|3|543382-543668|PILER-CR,CRT,CRISPRCasFinder
GTTTTAGTTACTTATTGTGAAATGTAAATTTTATTTCTCCTACGCTTTTCTTATTTCTGTAAATAAGTTTTAGTTACTTATTGTGAAATGTAAATTTTTCTACTCCTGCTTCTAAAATGTCGTTTATAAGTTTTAGTTACTTATTGTGAAATGTAAATCTAAAACATCCTTCACTGTATCAACTCCTTTCTATATTTTAGTTACTTATTGTGAAATGTAAATACAATAATAGGATATTTTGGATTTGTCTGCGTTCCTGTTTTAGTTACTTATTATGAAATGTAAAT

>CP025221|3|1|543382-543668|PILER-CR
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTATTTCTCCTACGCTTTTCTTATTTCTGTAAATAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTTCTACTCCTGCTTCTAAAATGTCGTTTATAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	CTAAAACATCCTTCACTGTATCAACTCCTTTCTAT
ATTTTAGTTACTTATTGTGAAATGTAAAT	ACAATAATAGGATATTTTGGATTTGTCTGCGTTCCT
GTTTTAGTTACTTATTATGAAATGTAAAT

>CP025221|3|2|543382-543668|CRT
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTATTTCTCCTACGCTTTTCTTATTTCTGTAAATAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTTCTACTCCTGCTTCTAAAATGTCGTTTATAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	CTAAAACATCCTTCACTGTATCAACTCCTTTCTAT
ATTTTAGTTACTTATTGTGAAATGTAAAT	ACAATAATAGGATATTTTGGATTTGTCTGCGTTCCT
GTTTTAGTTACTTATTATGAAATGTAAAT

>CP025221|3|2|543383-543668|CRISPRCasFinder
TTTTAGTTACTTATTGTGAAATGTAAAT	TTTATTTCTCCTACGCTTTTCTTATTTCTGTAAATAAG
TTTTAGTTACTTATTGTGAAATGTAAAT	TTTTCTACTCCTGCTTCTAAAATGTCGTTTATAAG
TTTTAGTTACTTATTGTGAAATGTAAAT	CTAAAACATCCTTCACTGTATCAACTCCTTTCTATA
TTTTAGTTACTTATTGTGAAATGTAAAT	ACAATAATAGGATATTTTGGATTTGTCTGCGTTCCTG
TTTTAGTTACTTATTATGAAATGTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP025221.1\|AVV08826.1\|535194_537255_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|226234
CP025221.1\|AVV08837.1\|545449_545809_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131113
CP025221.1\|AVV08832.1\|540490_540784_+\|PTS-galactitol-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908
CP025221.1\|AVV08829.1\|538372_538771_+\|hypothetical-protein	unknown	unknown	unknown
CP025221.1\|AVV08825.1\|534435_535086_+\|transaldolase	unknown	unknown	gnl\|CDD\|223254
CP025221.1\|AVV08843.1\|552232_553648_+\|lincomycin-resistance-protein-LmrB	unknown	unknown	gnl\|CDD\|129794
CP025221.1\|AVV08838.1\|545815_546274_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378956
CP025221.1\|AVV11231.1\|548591_549023_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
CP025221.1\|AVV08836.1\|544744_545425_+\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153212
CP025221.1\|AVV08840.1\|549069_550500_-\|capsule-biosynthesis-protein-CapA	unknown	unknown	gnl\|CDD\|225399
CP025221.1\|AVV08834.1\|542209_543145_+\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929
CP025221.1\|AVV08839.1\|546655_548491_+\|lmo0514-family-class-1-internalin	unknown	unknown	gnl\|CDD\|380190
CP025221.1\|AVV08842.1\|551716_552085_-\|DUF1304-domain-containing-protein	unknown	unknown	gnl\|CDD\|226282
CP025221.1\|AVV08827.1\|537258_537861_+\|phosphosugar-isomerase	unknown	unknown	gnl\|CDD\|223865
CP025221.1\|AVV08833.1\|540798_542070_+\|PTS-galactitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226298
CP025221.1\|AVV08835.1\|544059_544638_+\|hypothetical-protein	unknown	unknown	unknown
CP025221.1\|AVV08830.1\|538781_539432_+\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
CP025221.1\|AVV08831.1\|539428_540475_+\|galactitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|176198
CP025221.1\|AVV08841.1\|550620_551436_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
CP025221.1\|AVV08828.1\|537888_538356_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129

Protein	Function_ID	Function_description	E-value
CP025221.1\|AVV08826.1\|535194_537255_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	3.95572e-80
CP025221.1\|AVV08837.1\|545449_545809_-\|hypothetical-protein	gnl\|CDD\|131113	TIGR02058, lin0512_fam, conserved hypothetical protein. This family consists of few members, broadly distributed. It occurs so far in several Firmicutes (twice in Oceanobacillus), one Cyanobacterium, one alpha Proteobacterium, and (with a long prefix) in plants. The function is unknown. The alignment includes a perfectly conserved motif GxGxDxHG near the N-terminus. [Hypothetical proteins, Conserved].	5.62162e-67
CP025221.1\|AVV08832.1\|540490_540784_+\|PTS-galactitol-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	3.06007e-27
CP025221.1\|AVV08828.1\|537888_538356_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	3.45565e-37
CP025221.1\|AVV08825.1\|534435_535086_+\|transaldolase	gnl\|CDD\|223254	COG0176, MipB, Transaldolase [Carbohydrate transport and metabolism].	1.91243e-61
CP025221.1\|AVV08843.1\|552232_553648_+\|lincomycin-resistance-protein-LmrB	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	4.42897e-80
CP025221.1\|AVV08838.1\|545815_546274_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|378956	pfam12802, MarR_2, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.	1.03599e-12
CP025221.1\|AVV11231.1\|548591_549023_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	4.03126e-27
CP025221.1\|AVV08836.1\|544744_545425_+\|type-1-glutamine-amidotransferase	gnl\|CDD\|153212	cd01741, GATase1_1, Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. This group contains a subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. GATase activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate. Glutamine amidotransferases (GATase) includes the triad family of amidotransferases which have a conserved Cys-His-Glu catalytic triad in the glutaminase active site. In this subgroup this triad is conserved. GATase activity can be found in a range of biosynthetic enzymes, including: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase , anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase, cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. Glutamine amidotransferase (GATase) domains can occur either as single polypeptides, as in glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase.	6.36121e-61
CP025221.1\|AVV08840.1\|549069_550500_-\|capsule-biosynthesis-protein-CapA	gnl\|CDD\|225399	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane].	1.97856e-100
CP025221.1\|AVV08834.1\|542209_543145_+\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	2.38027e-153
CP025221.1\|AVV08839.1\|546655_548491_+\|lmo0514-family-class-1-internalin	gnl\|CDD\|380190	NF033186, internalin_K, class 1 internalin InlK. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. Members of this family are internalin K (InlK), a virulence factor. See articles PMID:17764999. for a general discussion of internalins, and PMID:21829365, PMID:22082958, and PMID:23958637 for more information about internalin K.	8.29186e-120
CP025221.1\|AVV08827.1\|537258_537861_+\|phosphosugar-isomerase	gnl\|CDD\|223865	COG0794, GutQ, Predicted sugar phosphate isomerase involved in capsule formation [Cell envelope biogenesis, outer membrane].	1.15952e-75
CP025221.1\|AVV08833.1\|540798_542070_+\|PTS-galactitol-transporter-subunit-IIC	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	7.01085e-178
CP025221.1\|AVV08830.1\|538781_539432_+\|ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	4.74405e-108
CP025221.1\|AVV08831.1\|539428_540475_+\|galactitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|176198	cd08236, sugar_DH, NAD(P)-dependent sugar dehydrogenases. This group contains proteins identified as sorbitol dehydrogenases and other sugar dehydrogenases of the medium-chain dehydrogenase/reductase family (MDR), which includes zinc-dependent alcohol dehydrogenase and related proteins. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Related proteins include threonine dehydrogenase, formaldehyde dehydrogenase, and butanediol dehydrogenase. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Horse liver alcohol dehydrogenase is a dimeric enzyme and each subunit has two domains. The NAD binding domain is in a Rossmann fold and the catalytic domain contains a zinc ion to which substrates bind. There is a cleft between the domains that closes upon formation of the ternary complex.	0
CP025221.1\|AVV08841.1\|550620_551436_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	5.01016e-50
CP025221.1\|AVV08842.1\|551716_552085_-\|DUF1304-domain-containing-protein	gnl\|CDD\|226282	COG3759, COG3759, Predicted membrane protein [Function unknown].	1.10012e-41

>CP025221.1|AVV08834.1|542209_543145_+|ribose-phosphate-pyrophosphokinase
MAGKMKLFSVTSERPLATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNSNVNERLMELLIMVDALKRASVHSINIIMPYYGYARQDRKARSREPITAKLMANLIQRAGANRLITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENYGEKDVVVVAPDHSGVVRARRIADRLNAPIAILNRKPRPHEDEIMSVIGDVKGKVAIVVDDIIDTGVRATTSADILLEKGAVEVIACATHSVMAGNATERLQNSSIKEVITSDSIDLPEDKQFDKLTTISIGRILGRAIEGVQENRSLHPLF
>CP025221.1|AVV08833.1|540798_542070_+|PTS-galactitol-transporter-subunit-IIC
MDIILDFFKYIIGLGVTVMMPIIITILGVIFRKKISVAFKAGLTVGVGFVGLGVITSLMLTTITPVTKALVENYNFKLTATDIGWGVGSSLAWGTEVVPFVFVAIIATNILMIAFKWTKTMDVDIWNYWQPLFIASALYLTTGSMIIAVLSSIINMAIIFKIADWTQKDVEDVLGLEGISLPQIQTTGWALVGYPMNWLLGKIPGVRKINWSTEKVQSRLGIFGEPMLMGLIIGGGLAAIAQMPLSQVLQTGVTIAASLVLIPRMVSLLMDGLTVISEAAHEFMEKRFPGRELFIGLDSAVGIGHPFVLSLGLLMIPITLILAFILPGNKVLPLADLTALPFYMIFAIVPSKGNLFRGIFTGIVIVIITLYLSGAAAPLMTELAGQIGYNIPKDAVEVTSLAVGTQWYTWIVYYGLHWFGGIL
>CP025221.1|AVV08832.1|540490_540784_+|PTS-galactitol-transporter-subunit-IIB
MKKKRIYVCCGTGIATSTVISKKVRAVLDEKRIPYEISQCTVQEVASKVSTSKPDIIVSSTTVTGDVGDVPVVIGRSFLTGLKKQETIDEILAILQD
>CP025221.1|AVV08831.1|539428_540475_+|galactitol-1-phosphate-5-dehydrogenase
MKALKLYGKRDLRYEEADMPTIEEPDDVILKVKTVGICGSDISRYSKLGPYVPGMVWGHEFSGEVIEVGSEVTDIEIGDRAAGCPALYCGECEYCKKGEFARCRKLTVIGARHPGAYAEYIKLPAENVVKIPDELDYEAAALVEPSAVVVHGFYHTKLQAGDDVVVVGSGNIGLLAIQWAKVFGARRVIAIDVDDKKLALAKEVGADVVINSLKEDPLEVVAAHTDGLNADLVVEAAGSPITSAQVFAYAKKGGGVVFLGIPYADVTIERFYFEKIVRSELTVWGSWNAISAPFPGKEWQTTIHFLANKQINIEPMITHRLSLAEGPEVFERIYERNEFFGKVLFFPE
>CP025221.1|AVV08830.1|538781_539432_+|ribulose-phosphate-3-epimerase
MAKIVPSVFGADIGRINEQLQVLEKNDIDLLHVDMMDGSFVPNIAFGPDQIKMMKKGTKLQFDVHMMVYEPDRYIPRLVEAGAHMITVHQEATTHLHRTIQLIKSYGVRAGVVLNPGTPPSTLEYVLDDIDCILLMTVNPGLGGQKFFQSSLEKIRKTKAYIGNRPIQIEVDGGVNDELAKECTLAGADLIVVGSYLFEGDIEANLEKLAKGVLTE
>CP025221.1|AVV08829.1|538372_538771_+|hypothetical-protein
MGSFFASFVDWLIGSPGRFVVNLIEDNMLIFMVVVMIYATTILYAKWTLAYYLPKKMSQLAEMKTWELDELYAAWQTEKKALPWYILVPSRNEFWVKSARNAPESTKLLHFSQQKLKLSDKEKLQKIIEIQS
>CP025221.1|AVV08828.1|537888_538356_+|PTS-sugar-transporter-subunit-IIA
MDVLEYFKEEMVRFSNEQDKEKLLTEMAEQLCEVGAVKPSYKDAVIKREKVFPTGLLTAHAGVAIPHTDSEHVIRPVVAVRILKKPVSFIEMASDNEAIDVRIVFMMALRSADEQLDMLQTLIQLIQDEEVMTTLLKAQETGDVLSAIEHFSKNN
>CP025221.1|AVV08827.1|537258_537861_+|phosphosugar-isomerase
MDKQAILNNIHQTWQEEANAISRLPEVTSEEALVKTVEKIAECTGKIVVAGCGTSGVAAKKLVHSFNCIERPAVFLTPSDAVHGTLGVLQKEDILILISKGGNTGELLNLIPACKTKGSTLIGVTENPDSVIAKEADIFFPVSVSKEPDPFNMLATASTMAVIASFDAVIVCLMTYMNYTKEQFSVIHPGGAVGNKLLNK
>CP025221.1|AVV08826.1|535194_537255_+|PTS-sugar-transporter-subunit-IIA
MYLDNRSKTLFQEVIKNPNITNKQLEVKYKLSRYQISYSFQKVNEWLKWKNYPEVKRSKNGRFILEPELTALFSEKETRDPSVEYLPSENERANLILLMLLTSKEELSLAHFTTKIQVSKNTILRDLKVAQKLLPKETTVTYSRASGYQLAGSEWELRKVLTQVVSSVKEMFRGEHYFLSYSGIEKVQLMEIRRTLEEAEAMMQIKFTYEQIELLPYLLSVMFLRIRDRRLIDTAFHIDEKSLSDTREYHITDILLEKTGPVPEQERLFITLQLLTTNIFSGEILTEKLTEDLEKVVLTCLDLFEKKALVSLKNKHILIEKLLLHLKPAYYRIKYQMNLEDTLYEKFNQEFEALNFIVKEAFDPLAKFIGREIPAGEIFFISLFIGSDMIPQNDIYHKQKRAIVLCPSGVTFSKIMENILVKLFPEIHFYPTISVREYAFFKAEVDIVFSSIPLKDGENVFVVQPFMNDIEKTQLRQHVLQNLFGMGNQLTSIDKIMEVVERNADIKDPNAIRDGIIDILSANTATDENKRVKKVYLHDLITEDNIMICEDVKNYQEAIRLASQPLLLQQAITANYVKTMIDNHKFHDPYIIIGEDIAIPHAMPNAGVNRLAMSLLVVKNGVYFSETEQVHFVIVIAPVDKEQHIEALYQIVHLAENHQILDDLLENVTKEKIMQTINQLVIREDE
>CP025221.1|AVV08825.1|534435_535086_+|transaldolase
MHLDSANLDDVKKIQASSIFKGITTNPTILVKEKCNRQTAINRILELTDKQVFVQTVGFTYEEILADARMLLTMFGKDKIAIKIPAHEAGTNVIDTLKKEDKTIQILGTAIYSADQAITAALVGADFVAPYVNRMSAANIDPFKEISQMRHFFDKKALKTQIMAASFKHSGQVMQAYESGADTVTIPYEIYSQMTNKVLAVEAIRVFNEDAVLYEK
>CP025221.1|AVV08835.1|544059_544638_+|hypothetical-protein
MKKILVPILLLATILASCSSPNEKITKDTKISKTITIRADYKVPKDIKELEDDSANIVKVKFLQNKTIGKDGSTISEIEILTSYKGNLEKGSKVDISEPWYLSDGKYVAVENYIALDKEQEYTIFLGEKDKDTYPLSSLGYGKFGGSLKEDQAVLADFNILGEVQKFDFISENTEEVKNYQLIKEQVAGKYK
>CP025221.1|AVV08836.1|544744_545425_+|type-1-glutamine-amidotransferase
MIIDVLQHVPHEGPGLIANWARENQHQLKIHSLFEENAHVPNDSDFLIVLGGPMGINDTAEFPWLKDERKLIKRLSEQHKPVFGVCLGAQQIAATFGSEITVNKEKEVGWFPVKRTSDKLSFFPESLNVFHWHQDTFALPAGATRLFASEGCLNQAFLYGENIIGLQFHFEMEKAGIETILQIDEAFITPGKYVQSVEVMQEKDVPEDNKQMLEAILDYLINPKTI
>CP025221.1|AVV08837.1|545449_545809_-|hypothetical-protein
MEQILFIQTGFGVDVHGQNITKAAERAVRNAIFTNSMPGIQGLLPDGDLQNMVVNIKLALPCDADQLDEDTIRAIIPYGTVTIEKMAGGMMTTSGIFLEDKEDKNDLMYIVNASVETGY
>CP025221.1|AVV08838.1|545815_546274_-|MarR-family-transcriptional-regulator
MNNEQNMNQQIALFYFGYKAFTETADLIIAKHSLKRLHHRILFFTARMPGLTINELLTFLEISKQALHQPLAELKERELLTIEQGRRDKRQRCIFLTAAGKELENELGAAQRKQMSEIFTNSADTDGMHFTEVMEGYAKNRPGAAFIKDFKE
>CP025221.1|AVV08839.1|546655_548491_+|lmo0514-family-class-1-internalin
MKKALKLFLAMICMFIMIYPSTAAHAEETNIVNIPDANLKTYLNGLLKQASDAPITKTQMNTIQTVTLSGSTYTDLTGLEEAGNLVTLSINNTNIQTLEPIKNQTSLTYLTVGGDNVKDSLFVDLNGLVNLQSLSINGSEVTHNVFKTFNKLPKLTYLYAQNSMKITDISALASLPALTTLFLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNETNQTLYLPFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSARLSITEDGITVSGVTKEEFDNLDEIEYNARYDFPTGSYPTPPSMTSYTISSGTYDQYFDISHTLDLTADESFDYNQYDTTSEEQFLKDVHAETDDGTAVKSDFDQVVKLDVPGEYTVTLNAENAAGLKATPVTVKVTVHEKPVITSDSQISYKKETTKSVDEFLKEIHGSVTGNAVLTSDFDKVVDLNTPGEYTVTLNAINDRGQKADPVTVVVTVTTSDSGHVNPVPPTPEVKPTPQEETDQTIIPEPQSETTEDSVKEDQAKDGQAKSEEKADKTSLTTKENKVEKSEKTNQPKTKALPQTGDTNKTALPIAGVMLSLAALLIFRKSKS
>CP025221.1|AVV11231.1|548591_549023_+|universal-stress-protein
MEKYHRILVAVDGSEPAKLAFEKGLELALKLDGVLGIASIVDLRAFSPNVSYDGSLEEKAELELKTSVNEYAEKARTAGVKQVETFVAKGNPKILLSTDIPAEFQADLIICGATGMNRVEKLVLGSVSSYIMAHAICDTLIAR
>CP025221.1|AVV08840.1|549069_550500_-|capsule-biosynthesis-protein-CapA
MKRRTYVIITGLVLVFIAGAFWITNSTNQSDQKATQTEPIKKISPANVKTISSEAKKTLNSLASSGADKASISDLKQLIKELKSYPTEKNDSGVYLQNLTACLEAVKSYTTGKADEKALGKVYPDFLASEQKLSAIEKTNQYDWFYAAAATNQQGLKEKGVVTLTMVGDNSFGTYPETPEHLKFDNVFQKNNGNNTYVYNNCLPWFKSDDYTVINAESAFTNATKAENKMWRIKSDPAHVAFLPASGVDAANLANNHTMDYFQVGYDDTLKAFKENNIPVFNTDAPLETTIKGMKTVLLGYDCRMSQQSPAYLERIVKDVKKYKKEDTLVIVNMHWGVEYRETPTDYQTQFGHAILDAGADIIMGSHPHRLESVEKYKDKYIVYSMGDFAFGADPTLLSRMTSMFQLRFTKEDNKIVLKDISIVPTYENSDGSTTENNYQPLPVFGDDAKKIVDELNRISKPIEGGVTEYTYFDPF
>CP025221.1|AVV08841.1|550620_551436_-|histidine-phosphatase-family-protein
MKKNIFKLLMALCAVLLIAGCGNSTSADKKETKETKEDGTVTFYVVRHGKTMLNTTDRVQGWSDAVLTPAGEEVVKSAGKGLKDVDFSAAYSSDSGRAIQTANLILKESDKSADKEVQTDPRFREFNFGSYEGDLNENMWTDIAKSQGKTLEEWQKAGLSPKDFANSVAALDKTRVKEGENWPAEDYATIQARLKEGLTDVAKKESKNGDSNVLLVSHGLSIGALLDTIEPGYKLPAEGIKNASVTKITYKDGKFTIGDVNDLSYVEKGSK
>CP025221.1|AVV08842.1|551716_552085_-|DUF1304-domain-containing-protein
MAILAFILTFIVMIEHIYIMILEMFFANTKLAAKTFGVEKELLANKKVQTLFANQGLYNGFLAAGLVWGLFFAGAGMAETVQIFFLSCVVVAALFGGATSSKGILVKQGLPAVLALVVVLLV
>CP025221.1|AVV08843.1|552232_553648_+|lincomycin-resistance-protein-LmrB
MQQEATGGQKIRPIPIIASFLMAGFIGLFSETALNMALSDLIQVFDISSATVQWLTTGYLLTLGILVPISGLLLQWFTTRGLFFTAVSFSIAGTLIAALSPTFAMLMIGRVVQAVGTALLLPLMFNTILLIFPEHKRGSAMGMIGLVIMFAPAVGPTISGLILENLTWNWIFWISLPFLIIALLFGMKFMQNVSVVTKPKIDILSIILSTLGFGGVVFAFSSAGESGWGSATVLVSIIVGGLALGLFVWRQLTMEKPLMDLKVFKYPMFTLGLILVFISFMMILSTMILLPLYLQNSLALAAFSAGLVLLPGGVLNGLMSPFTGRLFDAYGPRALVIPGFIVAVVALFFLTRIEVGTSALTIIVLHSVLMIGISMVMMPAQTNGLNQLPPKLYPDGTAIMNTLQQVSGAIGTAVAITIMSAGQKAYMETAQGMGPEQMVASLTAGIQNAFVFGLIMACIGLLCSLFIRKAK

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Crispr_ID: CP025221_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025221_4

2559969-2560130

Orphan

Consensus_repeat	Method
TTTTTTTATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGG	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of CP025221_4

>merge|CP025221|4|2559969-2560130|CRISPRCasFinder
TTTTTTTATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGGGATTGGTTGAATTTAATAATTTGTGCTTCCCTTTTCGGGTTGTTCGTCCACTTTTTTTAATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGG

>CP025221|4|3|2559969-2560130|CRISPRCasFinder
TTTTTTTATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGG	GATTGGTTGAATTTAATAATTTGTGCTTCCCTTTTCGGGTTGTTCGTCCACT
TTTTTTAATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGG

Protein	Signature genes	Signature genes Name	Protein_function
CP025221.1\|AVV10803.1\|2565553_2566309_-\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
CP025221.1\|AVV10793.1\|2551578_2554854_-\|glycosyl-hydrolase-family-31	unknown	unknown	gnl\|CDD\|224418
CP025221.1\|AVV10805.1\|2567679_2568690_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
CP025221.1\|AVV10790.1\|2545258_2545678_-\|hypothetical-protein	unknown	unknown	unknown
CP025221.1\|AVV10791.1\|2546627_2550560_-\|glycosyl-hydrolase-family-31	unknown	unknown	gnl\|CDD\|224418
CP025221.1\|AVV11275.1\|2562315_2562489_-\|hypothetical-protein	unknown	unknown	unknown
CP025221.1\|AVV10799.1\|2560537_2561281_-\|carboxylesterase	unknown	unknown	gnl\|CDD\|224561
CP025221.1\|AVV10795.1\|2556200_2556665_-\|SsrA-binding-protein	unknown	unknown	gnl\|CDD\|376590
CP025221.1\|AVV10798.1\|2560204_2560438_-\|preprotein-translocase-subunit-SecG	unknown	unknown	gnl\|CDD\|224233
CP025221.1\|AVV10788.1\|2543572_2544469_-\|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
CP025221.1\|AVV10802.1\|2564019_2565552_-\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|235463
CP025221.1\|AVV10794.1\|2555236_2556145_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP025221.1\|AVV10800.1\|2561463_2562183_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP025221.1\|AVV10797.1\|2559095_2559842_-\|carboxylesterase	unknown	unknown	gnl\|CDD\|224561
CP025221.1\|AVV10796.1\|2556680_2559062_-\|ribonuclease-R	unknown	unknown	gnl\|CDD\|273947
CP025221.1\|AVV10789.1\|2544513_2545083_-\|YdcF-family-protein	unknown	unknown	gnl\|CDD\|99750
CP025221.1\|AVV10801.1\|2562591_2563884_-\|enolase	unknown	unknown	gnl\|CDD\|234617
CP025221.1\|AVV10804.1\|2566354_2567545_-\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
CP025221.1\|AVV10792.1\|2550574_2551519_-\|lmo2445-family-class-3-internalin	unknown	unknown	gnl\|CDD\|275380
CP025221.1\|AVV10806.1\|2568723_2569770_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263

Protein	Function_ID	Function_description	E-value
CP025221.1\|AVV10793.1\|2551578_2554854_-\|glycosyl-hydrolase-family-31	gnl\|CDD\|224418	COG1501, COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism].	0
CP025221.1\|AVV10805.1\|2567679_2568690_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
CP025221.1\|AVV10802.1\|2564019_2565552_-\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	gnl\|CDD\|235463	PRK05434, PRK05434, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.	0
CP025221.1\|AVV10791.1\|2546627_2550560_-\|glycosyl-hydrolase-family-31	gnl\|CDD\|224418	COG1501, COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism].	0
CP025221.1\|AVV10804.1\|2566354_2567545_-\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
CP025221.1\|AVV10799.1\|2560537_2561281_-\|carboxylesterase	gnl\|CDD\|224561	COG1647, COG1647, Esterase/lipase [General function prediction only].	1.94931e-122
CP025221.1\|AVV10795.1\|2556200_2556665_-\|SsrA-binding-protein	gnl\|CDD\|376590	pfam01668, SmpB, SmpB protein.	2.29197e-92
CP025221.1\|AVV10798.1\|2560204_2560438_-\|preprotein-translocase-subunit-SecG	gnl\|CDD\|224233	COG1314, SecG, Preprotein translocase subunit SecG [Intracellular trafficking and secretion].	6.04836e-13
CP025221.1\|AVV10788.1\|2543572_2544469_-\|YafY-family-transcriptional-regulator	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	2.43734e-71
CP025221.1\|AVV10803.1\|2565553_2566309_-\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	7.345e-145
CP025221.1\|AVV10794.1\|2555236_2556145_+\|transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	6.61922e-08
CP025221.1\|AVV10800.1\|2561463_2562183_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	3.44979e-18
CP025221.1\|AVV10797.1\|2559095_2559842_-\|carboxylesterase	gnl\|CDD\|224561	COG1647, COG1647, Esterase/lipase [General function prediction only].	3.8639e-136
CP025221.1\|AVV10796.1\|2556680_2559062_-\|ribonuclease-R	gnl\|CDD\|273947	TIGR02063, Ribonuclease_R, ribonuclease R. This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA].	0
CP025221.1\|AVV10789.1\|2544513_2545083_-\|YdcF-family-protein	gnl\|CDD\|99750	cd06259, YdcF-like, YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been idenitified. The family also includes Escherichia coli sanA and Salmonella typhimurium sfiX, which are involved in vancomycin resistance; sfiX may also be involved in murein synthesis.	2.8348e-39
CP025221.1\|AVV10801.1\|2562591_2563884_-\|enolase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
CP025221.1\|AVV10806.1\|2568723_2569770_-\|transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	4.30628e-92
CP025221.1\|AVV10792.1\|2550574_2551519_-\|lmo2445-family-class-3-internalin	gnl\|CDD\|275380	sd00033, LRR_RI, leucine-rich repeats, ribonuclease inhibitor (RI)-like subfamily. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	5.15574e-06

>CP025221.1|AVV10797.1|2559095_2559842_-|carboxylesterase
MKITPPQPFLFEKGKRAVLLLHGFTGSSADVRILGRFLQENNYTCYAPQYRGHGVSPDLLLKTGPNDWWEDVLEAYDHLKSLGYTEIAVAGLSLGGLFSLKLGFSRPLKGIIAMSTPTRMDSSSPIIQGFLDYVRNYKKLEGKTTEQIDAEMVAYKDAPMNTIAKLKDEISGVVAEIDMIYAPIMVVQGEKDDMVDVSGAQLIYDTVESTKKELHWFKESGHVITLDKERKEVNQAILTFLDSLDWQE
>CP025221.1|AVV10796.1|2556680_2559062_-|ribonuclease-R
MEQKQMEEKIMNLLTSAPDKTFALEDLEIEIALNNADDFKLMVKALVKLEDSGTIVRSRKNRYALPEKMDLVKGTFRAHERGFGFVLPEEKEMDDIFIPPNEVKDAMNGDLVFATITKRKGDNLAEGTIKKIVERKTTQIVGTYMEDLAGTPIVMPDDKRLFGEVEIDLEDGLKPVDGHKVIVELTEYATGHARARGVVKSIIGHRNDPGVDILSIIHKHGISIGFPEEVMEQVSKAPDVVDDSDIGNRRDLRDQMIITIDGADAKDLDDAVTVKQLPNGNWKLGVHIADVTHYVTEGSPLDIEAQERGTSVYLVDRVIPMLPHKLSNGICSLNPQVDRFTMSCEMEINQEGHVVNHEIFESIIKTTERMTYTDVNDILVEKDEALREKYAPIVPMLEAMQNLAEILRRKREKRGAIDFDFKEARVVVDEDGHPEAVVMRERSAGEHLIEEFMLAANETVAEHFHWMDVPFIYRIHEDPKEDKLARFFEFITNFGLIVKGTANDIHPAALQQVLEEVKGKPEEMVVSTVMLRSMQQAKYDTVSAGHFGLSTDFYTHFTSPIRRYPDLIVHRLIREYLINGDVRPETLEKRAEELPEIAEHSSKMERRAVEAERETDELKKTEFMVDKVGERFIGIISSVTNFGLFIELPTTIEGLVHVSAMKGDYFKFHQNQLAMIGERTGQIYRIGDEVEVEVTKVDVDAREIDFALRSEGKPGPVSDKQKRQREKPIDKTRNFKSSSKNNRNKRRTGKSEDVKPKTERKDDEWYTKPKKKKKKKPFYQGVAKESPKKKKRR
>CP025221.1|AVV10795.1|2556200_2556665_-|SsrA-binding-protein
MPKGDGKLVAQNKKARHDYAIEETFEAGIVLQGTEIKSVRNARVNLKDSYARIDKGEIFLHNMHISPYEQGNRYNHDPLRTRKLLLHKKQISRLIGETKESGYSIVPLKMYIKDGYAKVLIGVARGKKKYDKRQDLKQKEAKRDIERAFKERQQ
>CP025221.1|AVV10794.1|2555236_2556145_+|transcriptional-regulator
MQNIGDTLKFIRKSKNLTQQETCTNALSRSNYQKIENNKIMPSMDRFIQILLNFNMTLEEFEFVKRDFTPSPKENILYLYSKIITSSETDILLDVISKCDDYLANQNDIFISDIKASLEGILLAEKEHNFELAREKVAYIWDRLSEADELFWNDILILRNIFFIFENETAQHIVNRLISQLKKYRYLYPTLSIEISLHVNRATYLILDEEYELALHYIELSIKIAKHNHYYLQFCMAVAKKGIVLYKLDQKQQGKHFMQRALRVAKVLEEERILNGIKNEIDYFLHDELQDLSLNEFTKIDI
>CP025221.1|AVV10793.1|2551578_2554854_-|glycosyl-hydrolase-family-31
MKRRTRKCSLVFILGILIFSCLSGFGTNVFAMDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK
>CP025221.1|AVV10792.1|2550574_2551519_-|lmo2445-family-class-3-internalin
MKKIIGLTFVAICCILFAPTIKAQADTVPLPAPIIEAFPVEAIAEAIAGELDKDSVNDTITQADLDTMTAIPLPSLGLTGEDLSVLNNEVFTNAIELAIWSNNIGELPDLSEALPALENIEANGANITVFPDANYPNLTNVDLSQNNFGFNIPKFVGMEGLVSINMENAGLSGYIAEDIWMNMPNLDSLILNENHLISIPEDIFLSQQLGTHSFANQTATYPPTTIKQGENLKVFVPFIYQALDFIAPSNHDLIIIKDNGRTLYEPPYPTYDGSYMYTIETAGLQPGEHLLEISLGYNSGEYTGWYDFPVTITE
>CP025221.1|AVV10791.1|2546627_2550560_-|glycosyl-hydrolase-family-31
MKKGMKQVCVSLAVVPLVWLNLGITQPLQVEVKAEETKKKETQKKANTETAKQLSKEEYAKLSAEEGLGNVLEATVTDNVITLKIDNGDEAEDDYLEISPLANNLLKVNLRPRNIENSPSTPMIDPNATFTAIGATIDLESDPMIISTDECTLEIDKEPARMTFKDKNGKTLLSESADGGIFDGGVRFKRGASDHVYGAYGISFSDGDLGMERDDTAADSNKTAQAGQQGNAGGPFMWSTAGYGLLVDSDGGYPYSVSDEEKLEFYYGDTIVEGRRYVKENVEMYLMSGEPEEIMSSYADVTGHTPMMPKWSLGFSNFEWGTNEEEFRENINTYRAKGIPIDSFAFDYDWKFYGDPTYGGDYGEFAWNTENFPSAKDTTLKSDMDALGVKMIGITKPRVVTNLEDGTATQQGKDADANGYWYPGQSAYEDYAFPVTVRSIDPYNADERNWWWSHSEDALDKGIVGWWNDETDKVSSNGADYWFGNFTTGFTSEAMYEGQRDYTNERVWQTGRTFYPGAQRYSTSTWSGDIGVQWKKGEVIDWANGMQEQPSTMLSTINLGQTKWGMDTGGFNANSGQVLNPDPELYSRWMEFSSLVPVFRTHGNQNQQRQPWFYGGTAEEVAKSSMTWRYSMIPYMYAYERQAYDSGVGLVQPLTFDNPTDENVVNLTDEWMFGDGLLAAPVLEEGAGSRDIYLPAGTWIDYNRGDVYEGNQTINYEVNDDDWTDVPMFVKQGAIMPMQQPQNYVGETAVKTIYLDTFASDKETSFTHYDDDGKSFDYEKDTYLKQKMTTSKTADTSTFTIGAKEGSYKADTENYIVKLHGNAAESVQVNGADSKVYDDLSALENADGSGYAVGSDVYGAVTYVKVPAQADADTVITTSGSASIVQTGTYEMETGSNFADTVADKPVAEKTYVDGYDKDGAGTTIYANVKDSGDYNVDLTYKNASSDNQALSIFVNGEYVKQTTLKPNTDWSVQSEALPLSAGKNSISYKVVTDTGDKADQVSLDKVNIGFTPTVAKVEAEEADLAGTLKVANDHWFYSGEGFVGGFGTAGDEIKFEVDVPADGEYVLNTRTANGTGMPQTLDLYTNGDYNSRVTFPSKGENWNIWSDTEKAVNLKAGTNKITFLRDGETTGNVNIDRILVSAEPINSPVQSEVNLLDNGGFERDAAATTNWVESHPDGQDKAYGVDSGSGVNPPESPAFGKQSAYFYLPGAYKQTLAQQIAVPVNNANYDVEAWVKVSKDDAAKAQMTVNNYDSSGGKTIDLVADDVWHYVTIKDVKVTKGNINTSFQMDSPGGTSIHIDNVRVMPSAE
>CP025221.1|AVV10790.1|2545258_2545678_-|hypothetical-protein
MYRLLSIAFFGIAVICLLFPWMSSGIDAATFELVYEPAYKLIWMQPIIIVGYLGFLCTIFIPKFQRGKNRIVPFIGILILVLGLLNLAVRPLFGFDSFNFSIIDAYVSELVEPAFLIAVSASILSLIMYAIYLKKSENL
>CP025221.1|AVV10789.1|2544513_2545083_-|YdcF-family-protein
MRSLRKIVIILIIIGFMYLLIVAAFMFSGSRTKPSENADTVLILGAKVKGNPAVPSLVLQERLDAAVAYLNEYPKAKVIVSGGQGADESATEASVMEEYLVNEGIARKRIETETKSKRTEENIKYSNAKFNLGKTVIVTSDYHMYRALMLAKRQGIDASGLPATSQTFAKYKGMMREVLSITYAWVFDH
>CP025221.1|AVV10788.1|2543572_2544469_-|YafY-family-transcriptional-regulator
MKLERILAILVMILERKVLASELAEKFEVSTRTIYRDMDTLLYAGFPVVALPGKNGGFTMLDTYKLATFTFSEAEKQILLEALEARSEFMLNDSQEILREKITLLQTEKPTSKHIFFDSATQHRQQIEAEVKRKIAYIQKAFTTNKQLEITYIAMSGAETTREISPQKLNLMDGSWYLEAYCHKRAAIRHFKLTRITSLKEIDKAIMEVEETEYQPAEMKRIVLEFPKNQLGKLLDYFLQEEMETGDDYVRVSFFYDLERNIIPFLLMFGSAVKILEPASLQKDYKSEVEKLYFNLNC
>CP025221.1|AVV10798.1|2560204_2560438_-|preprotein-translocase-subunit-SecG
MSTVLTVLLIIVSVLLITVIILQPGKSAGLSGAISGGAEQLFGKQKARGLELILHRTTIVLSVVFFAILIALAYFVQ
>CP025221.1|AVV10799.1|2560537_2561281_-|carboxylesterase
MSADRSFTLKAGNRAVLLLHGFAGTTEDVRELGEILAENGYTVHAPNFRGHGDEPAIFLKTTPEMWYEDAVAGYRQLEKDGYDEIAIVGVAMGGVFALKMAESFSPKAIVPLCANVNRKMRYIPIENYLTKQLKKQGIVEQEADQMLKNYLPEIDVMTEARATFYKNVARDIEKIHVPTMIGQGCQDEEIDADNANYIFKHIHTNDKQLCFYAGSGHDIVNDCEKDILEEDLIYFLDDLVWLEEKVV
>CP025221.1|AVV10800.1|2561463_2562183_-|alpha/beta-hydrolase
MIAEINGINLFYQIIGKGEPILLIHGNGQNHRSLKRMIDDLSTNHQVIAVDSRAHGKSEAGNTPLDFEVMALDMLSLLDYLKIDKYKVIGYSDGGIVALVMGKMQPNRQIASVVIGTNYHVNQIRFLPDLFCRVAYGAAFLLAPFSRFFERMKRQLALTIYHPHMSEADLQKISAPLLAVVGEYDLISSKDTKKMVHSVQHGEMVIVRNGLHYLPRQKPKQLLQLIHSFFSNLSAEIHK
>CP025221.1|AVV11275.1|2562315_2562489_-|hypothetical-protein
MLMKVKNSQASKVLETPKIKDAVVHEKSHPLAEKHSVQKKIINADMPQQQFHRRLMK
>CP025221.1|AVV10801.1|2562591_2563884_-|enolase
MSIITEVYAREVLDSRGNPTVEVEVYTEAGAFGRALVPSGASTGEYEAVELRDGDKARYLGKGVLKAVENVNDIIADKIIGFDVTDQIGIDKAMIELDGTPNKGKLGANAILGVSLAAARAAADELGVHLYEYLGGVNGKVLPVPMMNILNGGEHADNNVDVQEFMVMPVGAPNFKEALRMGAEILHALKAVLKGKGLNTGVGDEGGFAPNLKSNEEALETIMQAIKDAGYKPGEEVKLAMDAASSEFYNRETGKYELKGEGVTRTSEEMVTWYEEMITKYPIISIEDGLDENDWDGFKLLTERIGDRVQLVGDDLFVTNTTKLKEGIEKGIANSILIKVNQIGTLTETLDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPTRTDRVAKYNQLLRIEDNLADLAEYHGNDTFYNLKK
>CP025221.1|AVV10802.1|2564019_2565552_-|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase
MSKSPVAIIILDGFGKRAETVGNAVAQANKPNFDRYWANFPHGELKAAGLDVGLPEGQMGNSEVGHTNIGAGRIVYQSLTRIDKAIEEGEFQENKALNNAFTHTKENNSDLHLFGLLSDGGVHSHINHLVALLETAKDKGVKNVYIHAFLDGRDVAPQSSLEYLETLEKAISDLNYGAIATVSGRFYAMDRDKRWERVEKAYKAIVSAEGEKFEDPIELVKASYANDKNDEFVVPAIITKDGKPVATVKDNDAVIFFNFRPDRAIQLSNAFTDKEWDHFDRGADHPKNIKFVTMTLYNPSVDAEVAFEPIEMKNVIGEVLSNEGLAQLRIAETEKYPHVTFFMNGGRNEEFPGESRILINSPKVETYDLQPEMSAYEVTDALVEDIKNDKHDAIILNFANPDMVGHSGMLEPTIKAIEAVDENLGRVVDLILEKGGSAIIFADHGNSETMSTPEGKPHTAHTTVPVPVIVTKKGVTLREGGRLADVAPTMLDLLGVKKPAEMTGESLIQK
>CP025221.1|AVV10803.1|2565553_2566309_-|triose-phosphate-isomerase
MRKPIIAGNWKMNKTAAKAGQFAEDVKNNVPSSDAVESVVAAPALFLQELVRLTEGTNLRVSAQNCYFEDEGAFTGEISPFALADLGVSYVIIGHSERREYFHETDEDINKKAHAIFKHGMTPIICCGETLDQREAGQTDTWVRGQIRAALAGLTEEQVIKSVIAYEPIWAIGTGKSSTSADANETCAVIRAEVADAVSQKAADAVRIQYGGSVKPENIADYLAESDIDGALVGGASLEPASFLALLEAVK
>CP025221.1|AVV10804.1|2566354_2567545_-|phosphoglycerate-kinase
MAKKVVTDLDLKDKKVLVRVDFNVPMKDGKITNDNRIVAALPTIEYILEQNGKAILFSHLGKVKTEEDKEGKSLRPVAARLSELLGKEVKFVPTTRGPELEKAIDELKDGEVLLFENTRFEDIDGKKESKNDPELGKYWASLGDVFVNDAFGTAHRAHASNVGIASNLESAAGFLMEKEIKFIGGVVDNPARPLVAILGGAKVSDKIGVIENLLTKADKVLVGGGMTFTFMAAQGQEIGKSLLEADKVELAKGLLEKAGDKLVLPVDAVVSKEFSNDAPFHTVSADSIPADEMGLDIGQATIDLFTKELQGAKTVIWNGPMGVFELSNFAKGTIGVCEAIANLTDATTIIGGGDSAAAAMDLGFADKFTHISTGGGASLEYLEGKELPGVASISDK
>CP025221.1|AVV10805.1|2567679_2568690_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MTVKVGINGFGRIGRLAFRRIQNVEGIEVVAINDLTDAKMLAHLLKYDTTQGRFDGEVEVHDGFFKVNGKEVKVLANRNPEELPWGDLGVDIVLECTGFFTAQDKAELHIKAGAKKVVISAPATGDMKTIVYNVNHETLDGTETVISGASCTTNCLAPMAKVLEDKFGVVEGLMTTIHAYTGDQNTLDAPHPKGDFRRARAAAENIIPNTTGAAKAIGEVLPTLKGKLDGAAQRVPVPTGSLTELVTVLDKKVTVDEVNAAMEAASDPETFGYTSDQVVSSDIKGMTFGSLFDETQTKVLTVGDQQLVKTVAWYDNEMSYTAQLVRTLEYFAKIAK
>CP025221.1|AVV10806.1|2568723_2569770_-|transcriptional-regulator
MSDLINIQKKLLPDVLMIMQKRYQILRSIYFSEPVGRRTLAGMLGMSERVLRGEVEFLKAQGLVEIASSGMTVTKEGLVVFRDLESVMNQLSGLHSMEEQLAKKLQIKKCLVVQGDSDDTPWVREEMGRVAVEQLDMALTEKRNIVAVMGGSTMATVAEMMTTDFAKGRELLFVPGRGGIGEDLDNQANTICDKMATKTNTKHRVLYVPEQLGEEAYRSLLKEPAIQEGLRLVQSANAIILGIGDALAMAKRRHTGEDVLEKIIHRKAVGEAFGYYFDEQGEVVHKVPTFGLQFEDLAQIPHIIAVAGGTSKAKAIKSYMKSAPKNTILITDEGAAKSLLKGSNTLLK

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Crispr_ID: CP025221_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025221_5

2721399-2722359

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	CRISPRCasFinder
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	CRT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	PILER-CR

14 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of CP025221_5

>merge|CP025221|5|2721399-2722359|CRISPRCasFinder,CRT,PILER-CR
TGTGTGTTGATATTCAGAATAATATAGCTCTAAAACTTCGTCCAATGTACCTCGCCTTTTTTGTCTGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACACCGAAGTAGGTTAGGGTATCGCCGATTTTGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACCGACACATCGAGTCGTCCGGTTTTACTTACGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACAGAAAATCCGCAATCAATCCAAGCAGAAATGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACTCGAATGTGTAAGCTTCTGAGTAACCTAGCAGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACTAACCTTTAAAATTAAATTGAAGGTGCGGAGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACAACAATTGACCGGGAATTCATCAATAATTAGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACTCATATATTATGAATATCGAGATAGTGTTCGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACGTTTTCTATTTTGGTGACTTTAGTACTTTTGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACATGGGAATGCCATAGTTATTACCAATATTGGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACTATTCGATCTATCGGACGTGTCGACATTATGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACTATTGACTCGGAAATGAAAACAAAAGGTCAGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACTACATCGCTACCAATCAATCCGCTATTAAGGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACATCTATATTATCATACGTCAAGGAAGGGTAGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC

>CP025221|5|4|2721399-2722359|CRISPRCasFinder
TGTGTGTTGATATTCAGAATAATATAGCTCTAAAAC	TTCGTCCAATGTACCTCGCCTTTTTTGTCT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	ACCGAAGTAGGTTAGGGTATCGCCGATTTT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	CGACACATCGAGTCGTCCGGTTTTACTTAC
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AGAAAATCCGCAATCAATCCAAGCAGAAAT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TCGAATGTGTAAGCTTCTGAGTAACCTAGCA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TAACCTTTAAAATTAAATTGAAGGTGCGGA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AACAATTGACCGGGAATTCATCAATAATTA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TCATATATTATGAATATCGAGATAGTGTTC
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	GTTTTCTATTTTGGTGACTTTAGTACTTTT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	ATGGGAATGCCATAGTTATTACCAATATTG
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TATTCGATCTATCGGACGTGTCGACATTAT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TATTGACTCGGAAATGAAAACAAAAGGTCA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TACATCGCTACCAATCAATCCGCTATTAAG
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	ATCTATATTATCATACGTCAAGGAAGGGTA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC

>CP025221|5|3|2721399-2722359|CRT
TGTGTGTTGATATTCAGAATAATATAGCTCTAAAAC	TTCGTCCAATGTACCTCGCCTTTTTTGTCT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	ACCGAAGTAGGTTAGGGTATCGCCGATTTT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	CGACACATCGAGTCGTCCGGTTTTACTTAC
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AGAAAATCCGCAATCAATCCAAGCAGAAAT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TCGAATGTGTAAGCTTCTGAGTAACCTAGCA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TAACCTTTAAAATTAAATTGAAGGTGCGGA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AACAATTGACCGGGAATTCATCAATAATTA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TCATATATTATGAATATCGAGATAGTGTTC
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	GTTTTCTATTTTGGTGACTTTAGTACTTTT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	ATGGGAATGCCATAGTTATTACCAATATTG
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TATTCGATCTATCGGACGTGTCGACATTAT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TATTGACTCGGAAATGAAAACAAAAGGTCA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TACATCGCTACCAATCAATCCGCTATTAAG
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	ATCTATATTATCATACGTCAAGGAAGGGTA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC

>CP025221|5|2|2721465-2722359|PILER-CR
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	ACCGAAGTAGGTTAGGGTATCGCCGATTTT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	CGACACATCGAGTCGTCCGGTTTTACTTAC
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AGAAAATCCGCAATCAATCCAAGCAGAAAT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TCGAATGTGTAAGCTTCTGAGTAACCTAGCA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TAACCTTTAAAATTAAATTGAAGGTGCGGA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AACAATTGACCGGGAATTCATCAATAATTA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TCATATATTATGAATATCGAGATAGTGTTC
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	GTTTTCTATTTTGGTGACTTTAGTACTTTT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	ATGGGAATGCCATAGTTATTACCAATATTG
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TATTCGATCTATCGGACGTGTCGACATTAT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TATTGACTCGGAAATGAAAACAAAAGGTCA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TACATCGCTACCAATCAATCCGCTATTAAG
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	ATCTATATTATCATACGTCAAGGAAGGGTA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP025221.1\|AVV10944.1\|2723139_2723481_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
CP025221.1\|AVV10939.1\|2717524_2719051_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224619
CP025221.1\|AVV10947.1\|2728873_2729362_-\|hypothetical-protein	unknown	unknown	unknown
CP025221.1\|AVV10945.1\|2723477_2724344_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
CP025221.1\|AVV10936.1\|2708983_2709631_-\|hypothetical-protein	unknown	unknown	unknown
CP025221.1\|AVV10946.1\|2724344_2728349_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
CP025221.1\|AVV10950.1\|2731462_2731900_-\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
CP025221.1\|AVV10948.1\|2729371_2730757_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368093
CP025221.1\|AVV10938.1\|2716227_2717256_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|378455
CP025221.1\|AVV10949.1\|2731048_2731441_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
CP025221.1\|AVV10943.1\|2722487_2723150_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
CP025221.1\|AVV10941.1\|2719965_2720388_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133384
CP025221.1\|AVV10942.1\|2720510_2720873_-\|hypothetical-protein	unknown	unknown	unknown
CP025221.1\|AVV10952.1\|2732846_2733644_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
CP025221.1\|AVV10940.1\|2719092_2719944_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381359
CP025221.1\|AVV10937.1\|2709646_2710168_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239796
CP025221.1\|AVV10951.1\|2732094_2732841_-\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
CP025221.1\|AVV10933.1\|2705525_2706368_+\|DNA-directed-RNA-polymerase-subunit-delta	unknown	unknown	gnl\|CDD\|224824
CP025221.1\|AVV10934.1\|2706415_2707897_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
CP025221.1\|AVV10935.1\|2707997_2708885_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
CP025221.1\|AVV10944.1\|2723139_2723481_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.15214e-45
CP025221.1\|AVV10939.1\|2717524_2719051_+\|hypothetical-protein	gnl\|CDD\|224619	COG1705, FlgJ, Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion].	3.41835e-69
CP025221.1\|AVV10945.1\|2723477_2724344_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.76701e-129
CP025221.1\|AVV10946.1\|2724344_2728349_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
CP025221.1\|AVV10950.1\|2731462_2731900_-\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	2.08607e-102
CP025221.1\|AVV10948.1\|2729371_2730757_-\|hypothetical-protein	gnl\|CDD\|368093	pfam04740, LXG, LXG domain of WXG superfamily. This domain is present is the N-terminal region of a group of polymorphic toxin proteins in bacteria. It is predicted to use Type VII secretion pathway to mediate export of bacterial toxins.	5.37469e-18
CP025221.1\|AVV10938.1\|2716227_2717256_-\|ATP-binding-protein	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	3.84035e-115
CP025221.1\|AVV10949.1\|2731048_2731441_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	4.44953e-85
CP025221.1\|AVV10943.1\|2722487_2723150_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.59906e-114
CP025221.1\|AVV10941.1\|2719965_2720388_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	6.8812e-42
CP025221.1\|AVV10952.1\|2732846_2733644_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	5.34175e-53
CP025221.1\|AVV10940.1\|2719092_2719944_-\|aldo/keto-reductase	gnl\|CDD\|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	1.99645e-170
CP025221.1\|AVV10937.1\|2709646_2710168_-\|hypothetical-protein	gnl\|CDD\|239796	cd04268, ZnMc_MMP_like, Zinc-dependent metalloprotease, MMP_like subfamily. This group contains matrix metalloproteinases (MMPs), serralysins, and the astacin_like family of proteases.	3.94568e-09
CP025221.1\|AVV10951.1\|2732094_2732841_-\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	2.82266e-128
CP025221.1\|AVV10933.1\|2705525_2706368_+\|DNA-directed-RNA-polymerase-subunit-delta	gnl\|CDD\|224824	COG1912, COG1912, Uncharacterized conserved protein [Function unknown].	3.5648e-127
CP025221.1\|AVV10934.1\|2706415_2707897_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.77224e-108
CP025221.1\|AVV10935.1\|2707997_2708885_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.88589e-15

>CP025221.1|AVV10942.1|2720510_2720873_-|hypothetical-protein
MKKTSIIFIFCALLLTACSTTTKEIPRQTTEATGTIEQVETESILIKNFKIKNDNNTPELSVRFHISEKYHDETGNKIKRTELNKNDNIKIILTKDFQIQETSPAQIDPKYVQKIILLNK
>CP025221.1|AVV10941.1|2719965_2720388_-|MerR-family-transcriptional-regulator
MNIKQAADLFGLTVDTLRYYERVGVIPPVHRNESGYRDYKTSDLNWVYLVKNLRNAGLSVESLIEFATLAQLRETQNVEAAQKQVLVDQLKELDEKLAEMKKVRELLVYKIDSYDSHIAQFKAGELNADNVEKLWERDKF
>CP025221.1|AVV10940.1|2719092_2719944_-|aldo/keto-reductase
MKTVKLNNGVEVPILGFGTYQITDVAEAEQAVKDAIKAGYRHIDTAQSYMNEEAVGRGIAASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQPFNDVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEVNPFQQQAANLAVLRKEGVAIEAWAPFAEGKNDVFNNPVLTKIGAKYGKSAAQVILRWLVEQDIIVLAKSVKPERMAQNLAIFDFELTEADKEEIAGLDQGESQFFSHADPEMVKWMASRKLNV
>CP025221.1|AVV10939.1|2717524_2719051_+|hypothetical-protein
MDRKFIKPGIILLIVAFLVVSINVGAETGGSRTAQVNLTTSQQAFIDEILPAAQDGYRDGKLLTSVTLAQAILESNWGESGLSQNSNNLFGIKGTYKGKSVSMGTMEASGSTTANFRVYPSWKESIEDHTALITENARYQDAVGETNYRKALQAIKDGGYATDPDYVSKLVAIIERYNLDKYDVIYDKIESNQSLAAIGTVAENKEQEVIWSAPYNTENANKIETLENYSGRNLEISWEAKTEKGLWYFIRENNKDIGWVNSNALKISYHQKEDENVHLTKYVDDLSAHVYRLPSPEKQFDNGTIAKYDRKALQVDKKITRGGYAWFRISEGEKVIGWVRADKLNDRLYDRITEQTSYDGYALVSKSATDNVWTAPFNTKNAEKLAPLADYNNEKLEIVTRAKAGNTLWYQFKVDGKLVGWASEKDLNVFYTPAKEEPVKQVAYVKDPTAKLYNKPVESTSTNPKAVGFYYGKLLAVDKTATILGEDWLHLKDSQNSLGWIKAIDINS
>CP025221.1|AVV10938.1|2716227_2717256_-|ATP-binding-protein
MLNEQQITRLLYRLQDPVLEASLEETEGVLEVQVLEETANIKIALADPAVETDHFVHNIEELLTQFGVNEINIELEYLPAAVIDRIFQARDNILSEASETKFLAIASGKGGVGKSTVSANLAIALAQQGKKVGLLDADIYGFSIPVLLGTTESPHKENGQIIPVETHGIQMISMDFFVEQGEPVIWRGPMLGKMIKMFLEEVRWGKLDYLLIDLPPGTGDVALDIHTLIPKCNELIVTTPHYAAASVASRAGYMAAKNNHKIIGVIENMSYLTLADGQVLKVFGQGGGEKVAADLETQLLIQLPIEQPEPNGNGYVSALFNSSSTSGKAYKTLAEKIIPYLS
>CP025221.1|AVV10937.1|2709646_2710168_-|hypothetical-protein
MLKIFMFTVLFTILLIPSNVNAYTKLGYSLSKPTAKNFKFYINGSAISYKNIIINGAKSWNASPYINTVSMGRDVNPHFTISSSAKDRGATVAICETWTYKGTKVVAKNEVTTFKAFRSLSAGDKTETIAHEFGHGLGLGHVKTKNAIMLDVGFTKTIKPQTDDLNGIKSIYR
>CP025221.1|AVV10936.1|2708983_2709631_-|hypothetical-protein
MKKKIVFFMGLVSIVAMIGCSNDKNSTGKSIERIEIEKVETRNRVVSYRGKYLELAENIDELDESSPIIVTVIKESEAKSVTKESNGSDIPTEFYTMSEVKVKNIKKDETGALKENKKIKILEDSVENVSVDGEEYDLTIDGYKNMKEGEEYTLFIRKSTSGDNYVFTNAVLSKYPVEKVSDRDLFLEGEESVEETVDMKATYKEIYQEVLSEYN
>CP025221.1|AVV10935.1|2707997_2708885_-|TetR/AcrR-family-transcriptional-regulator
MKEKKQRIIKSAKEVFQKQGYLKTSVQDMVDAAGISKGTFYNYFTSKEELAIVIFKQEYSVLHQRLEYTMAQDGAKKDNFTECLKIIIHFYTENGEILNITFSQTMIDDDFNAFLQNVRLKNMEWVKYQLLEVYGEETKPYINDITMLLSGMAAMYVFASGSKNVNTGLIERAIPYVVRRLDALVKDILESGEIVFTEADTENLVPDQTMIRKKRLAKLREALEELNVGIENADIADSDKWQYKESMNALVGEINNNEAPRDFMVQGTLLYLKQHVPASLTKEVNKLEACVNGLL
>CP025221.1|AVV10934.1|2706415_2707897_-|MFS-transporter
MNSTAVERPVDVNGKSYSRSLLVVTMIIGAFVAILNQTLLATALPMIMDDLHITAATGQWLTTAFLLTNGIMIPITALLIEKISSKTLFITAMTVFTIGTIIASVAGSFPILLTGRIVQAAGAGIMMPLLQTIFLLIFPREKRGAAMGLMGLVIAFAPAIGPTLSGWIVDSYDWRVLFLILIPIAVIDIILAFFGMKKVVKLTDTKIDFLSIVMSSIGFGALLYGFSSAGNDGWGDTTVITMLIVGVVVIALFVWRQLVIDNPMLELHVFKYPVFSLSVILGSIVTMAMIGAEIVLPLYIQTIRGESALQSGLLLLPGAIIMGIMSPITGIIFDKIGAKWLTITGVTILTIGTIPFMFLTMDTPLWYIVVFYAVRFFGISMAMMPVSTAGMNALPNHLINHGSAVNNTIRQIAGSIGTAVLITVLTNVTKDNMPGKALMATDPASFAQKAQDASLDGMRAAFMVAAIFAAIGMILSLFLKTKKQEPIVKEYTK
>CP025221.1|AVV10933.1|2705525_2706368_+|DNA-directed-RNA-polymerase-subunit-delta
MTKQLLVLQSDFGISDGAVSAMYGVINSVSVDLQIYDLTHQIPQFNIWEASYRLLQTVTYWPENTIFVSIVDPGVGSKRRSVAVLTEDGHYIITPDNGTLTHIAHYGTIKEVRLIDEEKNRLPKSGASHTFHGRDIFAYTAARLAAGVINFEDIGPAAAPESIVSLSLSDSYLEGEQAFGTIDIIDRPFGNLWTNIRRTDFLELGANYGDSIEVLIKHHDRIVYKNFVTYSRSFADLRIGEPLIYVNSLDNLGLGINQGSFVDAYSVGTGTSWKVTLKKA
>CP025221.1|AVV10943.1|2722487_2723150_-|type-II-A-CRISPR-associated-protein-Csn2
MNFNFKLLDEPITIEDSTIFVIEDVRVFANVAKLFYQYDETEELKVFNTKQHPLKSSELMLVTDILGHDINSAATLKLIYTDLEQQLNEKPEVKSMIDKLTATISELIGYELLEHELDLEEDEITVIELFKALGIKIETKSDTVFEKLIEIVQVYKYLSKKKLLVLINVCSYLTEEELLELRRYISLYQVKVLFIEPRKIKGSPQVTLDPDYFLHVENSV
>CP025221.1|AVV10944.1|2723139_2723481_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRMLLMFDMPTDTAKERKAYRQFRRFILSEGFIMHQYSVYSKILLNGTASKAMLARLKQQNPKKGLITLLTVTEKQFARMVYLSGEQNKSVGNSDARLIFLGDAIDEF
>CP025221.1|AVV10945.1|2723477_2724344_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVNSHSKLSYKNQHLVFKSAYQHEMIHLSEIDVLILETTDITLTTMLINCLVAENILILFCDDKRLPIGKVLPFYGRHDSSLQLSKQLGWDSELKSEVWTEIISQKILNQNTFLSMLNYDEKADSLIKLHETLEIFDPTNREGHAARIYFNQLFGNDFTREQENDINSGLNYGYTLLLSIFARELVKSGCMTQFGLKHSNQFNDFNFASDIMEPFRPLVDQIVYEKRNEDFQVIKRSLFELFNKQFDYNDQHMFLTNIASDYTKKIVKVLNEEREGVPEFRI
>CP025221.1|AVV10946.1|2724344_2728349_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKPYTIGLDIGTNSVGWAVLTDQYDLVKRKMKISGDSEKKQIKKNFWGVRLFEKGETAAKRRMSRTARRRIERRRNRISYLQEIFAIQMNEVDDNFFNRLKESFYAESDKKYNRHPFFGTVEEEVAYYKDFPTIYHLRKELIDSQKKADLRLVYLALAHIIKYRGHFLIEGALDTKNTSIDEMFKQFLQIYNQVFANDIEEASLKKTEKNQEVAQILAEKFTRKDKLDKILSLYPGEKTTGVFAQFVNIIVGSTGKFKKHFNLHEKKDINCAEDTYDTDLESLLAIIGDEFAEVFVAAKNAYNAVVLSNIITVTDSTTRAKLSASLIERFENHKEDLKKMKRFVRTYLPEKYDEIFDDTEKHGYAGYISGKTKQADFYKYMKATLEKIEGADYFIAKIEEENFLRKQRTFDNGVIPHQLHLEELEAILHQQAKYYPFLREDYEKIKSLVTFRIPYFVGPLAKGQSEFAWLTRKADGEIRPWNIEEKVDFGKSAVDFIEKMTNKDTYLPKENVLPKHSLCYQKYMVYNELTKVRYIDDQGKTNYFSGQEKQQIFNDLFKQKRKVKKKDLELFLRNINQIESPTIEGLEDSFNASYATYHDLLKVGMKQEILDNPLNTEMLEDIVKILTVFEDKRMIKEQLQQFSDVLDGTVLKKLERRHYTGWGRLSAKLLVGIRDKQSHLTILDYLMNDDGLNRNLMQLINDSNLSFKSIIEKEQVSTTDKDLQSIVAELAGSPAIKKGILQSLKIVDELVSVMGYPPQTIVVEMARENQTTNKGKNNSKPRYKSLEKAIKEFGSQILKEHPTDNQELKNNRLYLYYLQNGKDMYTGQELDIHNLSNYDIDHIVPQSFITDNSVDNLVLTSSAGNREKGDNVPPLEIVQKRKIFWEKLYQGNLMSKRKFDYLTKAERGGLTEADKARFIHRQLVETRQITKNVANILHQRFNYKTDGNKDTMETVRIVTLKSALVSQFRKQFQFYKVREVNDYHHAHDAYLNGVVANTLLKVYPQLEPEFVYGEYHQFGWFKANKATAKKQFYTNIMLFFAQKDRIIDENGEILWDKRYLETVKKVLGYRQMNIVKKTEIQKGEFSNVTPNPKGKSNKLIPRKKDWDPIKYGGFDGSKMAYAIIIEYEKQKRKVRIEKKLIQINIMEREAFEKDEKTFLEEKGYHQPKVLIKVPKYTLYECKNGRRRMLGSANEAHKGNQMLLPNHLMALLYHAEKYEAIDGESLAYIEVHRALFDELLAYISEFARKYTLSNDRLDEINMLYERNKDGDVKSIAESFVSLKKFNAFGVHQDFSFFGTKIERKRDRKLNELLNSTIIYQSITGLYESRKRLDN
>CP025221.1|AVV10947.1|2728873_2729362_-|hypothetical-protein
MKEDILAVYKKFEINNLNMFFDDLIEYVNKYYTVFSKYISLDYLDAITRLDSTSLILGHSDDNFEIAIPFYTNKVIEGLNEEELSNQVSSLIWDLSAYMTEELCPSCNDSNLRLTTMVSREDTLVKFCDECLYTGIRNERVEIEEDLVPAPKKKVEEYLRGK
>CP025221.1|AVV10948.1|2729371_2730757_-|hypothetical-protein
MSRIDIAELNEFLHNLKSSNDEARRMLGKMQEVTNAYATDTSLKGKAIETSQAYFDQTYSVICKSLIEALDESEERLERYIREFGEQVDSSYNARIDAEMLQEAIFRLAEIKRKQEDLLQRMSASTGTLHEGEQQRLRTQFTDALEQEKILERYIAFEQSHGRFFDSFSELVYCAGKAVRELAANVTFNSQTGTYDIGKLDTNKFHALQKFLPKKKKYNFNEYEIRWNGAAHILLRGDVVDAEATAAYNDAVAKGELPKVSNQATESAEEINAVVNALKKGQDPITGQEISKAQSFGIAIGLVYMYVGGKYKGRKIKLPKNALENLEKQQAFKDKEVGGADIPNPNVGIVQSRVNLAENPTRFSPSKNAGMKHVRNRHYNPSKNAGQFTIPESDLKNILQSKQVVNTPVKQIESGDFERVIDIGKNMGTVKPSLGGQTTTWIKVITDKAGNIITTYPVPKP
>CP025221.1|AVV10949.1|2731048_2731441_-|30S-ribosomal-protein-S9
MAQVQYYGTGRRKSSVARVRLVPGDGKIVINNRDWEDYIPFAALREVIKQPLVATETLGNYDVLVNVHGGGYTGQAGAIRHGVARALLQVAPEYRPALKSAGLLTRDSRMKERKKPGLKGARRAPQFSKR
>CP025221.1|AVV10950.1|2731462_2731900_-|50S-ribosomal-protein-L13
MRTTYMAKPGEVERKWYVIDATGVSLGRLSSEVASILRGKNKPQFTPHIDTGDFVIIINAGKIGLTGKKATDKIYYRHSQYPGGLKSRTAGEMRTNNPEKLLELSIKGMLPKNSLGRQLFKKLHVYGGSEHEHAAQQPEVYELRG
>CP025221.1|AVV10951.1|2732094_2732841_-|tRNA-pseudouridine(38-40)-synthase-TruA
MTRYKAIISYDGSGFYGYQVQPNTRTVQAEIEKALTKMHKGKTVRVTASGRTDTGVHAKGQVIHFDSELDITAEKFQKALQVMTPFDISFLTVEEVPDDFHARFGTVGKEYRYVVKRTKIFDPFSRNFALHYPYELDISKMKLASKRLIGEHDFTSFCSARTERDSKVRTLYSIDFYEEDDETLVIAFQGNGFLYNMVRILTGTLLDAGQGRISPDDISEALLARDRQKLISKTAPPQGLYLWRVDYE
>CP025221.1|AVV10952.1|2732846_2733644_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MMDKMILGRYIPGNSWLHRIDPRAKITAVMAFIAIVFLANNWLTYALMFVYVLYLVLTSKVPFLFFIKGLQPIFWLILITLLLQVFFTKGGTVLVDLGLLQITTLGLANGAMMFCRFVLIIFMTTLLTLTTSPIELTDGLEKILAPFRLVHLPVHELALMLSISLRFIPTLMDETEKILKAQKARGVEFTSGKWSDRIKAIIPLLVPLFISAFKRAEDLAIAMEARGYRGGKGRTRFRLLRWRFADTFLLISLAVLSGLLFWLRS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP025221_2	2.3\|508035\|39\|CP025221\|CRT	508035-508073	39	CP025221.1	505830-505868	0	1.0
CP025221_2	2.6\|508269\|39\|CP025221\|CRT	508269-508307	39	CP025221.1	506064-506102	2	0.949
CP025221_3	3.4\|543604\|36\|CP025221\|PILER-CR,CRT	543604-543639	36	CP025221.1	693924-693959	2	0.944

1. spacer 2.3|508035|39|CP025221|CRT matches to position: 505830-505868, mismatch: 0, identity: 1.0

tatgccatgtttgaagattgtactagtcttgaagagctg	CRISPR spacer
tatgccatgtttgaagattgtactagtcttgaagagctg	Protospacer
***************************************

2. spacer 2.6|508269|39|CP025221|CRT matches to position: 506064-506102, mismatch: 2, identity: 0.949

cgtgccatgtttgctggttgtactagtcttgaagtgtta	CRISPR spacer
cgtgccatgtttgctggctgtactagtcttgaagcgtta	Protospacer
*****************.****************.****

3. spacer 3.4|543604|36|CP025221|PILER-CR,CRT matches to position: 693924-693959, mismatch: 2, identity: 0.944

acaataataggatattttggatttgtctgcgttcct	CRISPR spacer
acgataataggatattttggatttgcctgcgttcct	Protospacer
**.**********************.**********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP025221_5	5.5\|2721699\|31\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721699-2721729	31	KJ094022	Listeria phage LP-030-3, complete genome	16313-16343	0	1.0
CP025221_5	5.6\|2721766\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721766-2721795	30	KJ094023	Listeria phage LP-101, complete genome	19426-19455	0	1.0
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NC_003216	Listeria phage A118, complete genome	6554-6583	0	1.0
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	AJ242593	Bacteriophage A118 complete genome	6554-6583	0	1.0
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	KJ094022	Listeria phage LP-030-3, complete genome	14945-14974	0	1.0
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	MN172529	Listeria phage LP-039, complete genome	60277-60306	0	1.0
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	MT668624	Listeria phage LP-Mix_6.2, complete genome	61623-61652	0	1.0
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	NC_025440	Listeria phage WIL-1, complete genome	105560-105589	0	1.0
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	NC_047872	Listeria phage LMTA-94, complete genome	71109-71138	0	1.0
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	KJ591604	Listeria phage LMTA-148, complete genome	68215-68244	0	1.0
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	KJ591605	Listeria phage LMTA-57, complete genome	81858-81887	0	1.0
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	KJ094033	Listeria phage LP-048, complete genome	62734-62763	0	1.0
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	KJ668715	Listeria phage LMTA-34, partial genome	57972-58001	0	1.0
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	NC_042048	Listeria phage LMTA-34, complete genome	75832-75861	0	1.0
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	NC_041862	Listeria phage LP-064, complete genome	70234-70263	0	1.0
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	JX126918	Listeria phage LP-125, complete genome	70236-70265	0	1.0
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	NC_024360	Listeria phage LMSP-25, complete genome	75832-75861	0	1.0
CP025221_3	3.3\|543540\|35\|CP025221\|PILER-CR,CRT	543540-543574	35	NC_021539	Listeria phage LP-030-2, complete genome	18926-18960	1	0.971
CP025221_3	3.3\|543540\|35\|CP025221\|PILER-CR,CRT	543540-543574	35	KJ094023	Listeria phage LP-101, complete genome	22882-22916	1	0.971
CP025221_3	3.7\|543540\|36\|CP025221\|CRISPRCasFinder	543540-543575	36	NC_021539	Listeria phage LP-030-2, complete genome	18926-18961	1	0.972
CP025221_3	3.7\|543540\|36\|CP025221\|CRISPRCasFinder	543540-543575	36	KJ094023	Listeria phage LP-101, complete genome	22882-22917	1	0.972
CP025221_5	5.5\|2721699\|31\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721699-2721729	31	KP399678	Listeria phage vB_LmoS_293, complete genome	7920-7950	1	0.968
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	MT438761	Listeria virus P61, complete genome	72024-72053	1	0.967
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	MT178766	Listeria virus P100plus, complete genome	27249-27278	1	0.967
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	DQ003638	Listeria phage A511, complete genome	60814-60843	1	0.967
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	MT178767	Listeria virus P200, complete genome	27249-27278	1	0.967
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	DQ004855	Listeria bacteriophage P100, complete genome	27248-27277	1	0.967
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	MN128594	Listeria phage LP-066, complete genome	61773-61802	1	0.967
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	MK792752	UNVERIFIED: Listera phage vB-LmoM-SH3-3, complete genome	79360-79389	1	0.967
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	KJ094030	Listeria phage LP-083-2, complete genome	66939-66968	1	0.967
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	JQ797329	Listeria phage vB_LmoM_AG20, complete genome	60123-60152	1	0.967
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	KJ535721	Listeria phage List-36, complete genome	68224-68253	1	0.967
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	KJ094031	Listeria phage LP-124, complete genome	29054-29083	1	0.967
CP025221_3	3.1\|543411\|37\|CP025221\|PILER-CR,CRT	543411-543447	37	NC_009812	Listeria phage B025, complete genome	30705-30741	2	0.946
CP025221_3	3.3\|543540\|35\|CP025221\|PILER-CR,CRT	543540-543574	35	NC_009812	Listeria phage B025, complete genome	23381-23415	2	0.943
CP025221_3	3.7\|543540\|36\|CP025221\|CRISPRCasFinder	543540-543575	36	NC_009812	Listeria phage B025, complete genome	23381-23416	2	0.944
CP025221_5	5.2\|2721501\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721501-2721530	30	KJ094028	Listeria phage LP-083-1 contig 2, partial genome	18565-18594	2	0.933
CP025221_5	5.2\|2721501\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721501-2721530	30	DQ003641	Listeria phage P35, complete genome	34695-34724	2	0.933
CP025221_5	5.5\|2721699\|31\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721699-2721729	31	MH341452	Listeria phage PSU-VKH-LP040, complete genome	7933-7963	2	0.935
CP025221_5	5.5\|2721699\|31\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721699-2721729	31	DQ003637	Listeria phage A500, complete genome	7899-7929	2	0.935
CP025221_5	5.6\|2721766\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721766-2721795	30	NC_003216	Listeria phage A118, complete genome	20408-20437	2	0.933
CP025221_5	5.6\|2721766\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721766-2721795	30	AJ242593	Bacteriophage A118 complete genome	20408-20437	2	0.933
CP025221_5	5.6\|2721766\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721766-2721795	30	X85008	Bacteriophage A118 hol118 and ply118 genes	656-685	2	0.933
CP025221_3	3.5\|543411\|38\|CP025221\|CRISPRCasFinder	543411-543448	38	NC_009812	Listeria phage B025, complete genome	30704-30741	3	0.921
CP025221_5	5.5\|2721699\|31\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721699-2721729	31	NC_003216	Listeria phage A118, complete genome	7919-7949	4	0.871
CP025221_5	5.5\|2721699\|31\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721699-2721729	31	AJ242593	Bacteriophage A118 complete genome	7919-7949	4	0.871
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	MN693541	Marine virus AFVG_25M436, complete genome	24008-24037	5	0.833
CP025221_5	5.14\|2722294\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722294-2722323	30	MK327943	Escherichia phage vB_EcoM_G53, complete genome	71695-71724	6	0.8
CP025221_5	5.1\|2721435\|30\|CP025221\|CRISPRCasFinder,CRT	2721435-2721464	30	MK813941	Aeromonas phage 4_L372XY, complete genome	93420-93449	7	0.767
CP025221_5	5.8\|2721898\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721898-2721927	30	NC_041887	Rhodococcus phage Weasels2, complete genome	68085-68114	7	0.767
CP025221_5	5.9\|2721964\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721964-2721993	30	NC_015498	Glaciecola sp. 4H-3-7+YE-5 plasmid pGLAAG01, complete sequence	13562-13591	7	0.767
CP025221_5	5.11\|2722096\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722096-2722125	30	NZ_CP053711	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed4, complete sequence	17299-17328	7	0.767
CP025221_5	5.11\|2722096\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722096-2722125	30	NZ_CP053711	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed4, complete sequence	69337-69366	7	0.767
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_CP042479	Citrobacter freundii strain C50 plasmid pC50_001, complete sequence	5535-5564	7	0.767
CP025221_5	5.6\|2721766\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721766-2721795	30	NZ_CP043436	Campylobacter fetus subsp. venerealis NCTC 10354 plasmid p3226, complete sequence	2890-2919	8	0.733
CP025221_5	5.6\|2721766\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721766-2721795	30	NZ_CP016721	Lactococcus lactis subsp. lactis strain UC11 plasmid pUC11B, complete sequence	23276-23305	8	0.733
CP025221_5	5.6\|2721766\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721766-2721795	30	NZ_CP016727	Lactococcus lactis subsp. lactis strain UC08 plasmid pUC08B, complete sequence	23275-23304	8	0.733
CP025221_5	5.6\|2721766\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721766-2721795	30	NZ_CP008809	Campylobacter fetus subsp. fetus 04/554 plasmid pCFF04554, complete sequence	8547-8576	8	0.733
CP025221_5	5.6\|2721766\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721766-2721795	30	NZ_CP008812	Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-2, complete sequence	17700-17729	8	0.733
CP025221_5	5.6\|2721766\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721766-2721795	30	NZ_CP018792	Campylobacter sp. RM8964 plasmid pVIC8964, complete sequence	21826-21855	8	0.733
CP025221_5	5.6\|2721766\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721766-2721795	30	NZ_CP016699	Lactococcus lactis subsp. lactis strain 275 plasmid p275A, complete sequence	55457-55486	8	0.733
CP025221_5	5.6\|2721766\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721766-2721795	30	NZ_CP018794	Campylobacter sp. RM12175 plasmid pVIC12175-1, complete sequence	22093-22122	8	0.733
CP025221_5	5.6\|2721766\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721766-2721795	30	KC699836	Bacillus phage SIOphi, partial genome	2244-2273	8	0.733
CP025221_5	5.9\|2721964\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721964-2721993	30	NZ_CP015799	Borrelia mayonii strain MN14-1539 plasmid cp32-13, complete sequence	7241-7270	8	0.733
CP025221_5	5.11\|2722096\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722096-2722125	30	NC_014120	Paraburkholderia sp. CCGE1002 plasmid pBC201, complete sequence	170278-170307	8	0.733
CP025221_5	5.12\|2722162\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722162-2722191	30	NC_015427	Clostridium botulinum BKT015925 plasmid p4BKT015925, complete sequence	20826-20855	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_CP022274	Citrobacter freundii strain 18-1 plasmid pA18-1, complete sequence	53211-53240	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_CP010360	Enterobacter roggenkampii strain 35734 plasmid p35734-141.404kb, complete sequence	111873-111902	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_CP041048	Citrobacter sp. CF971 plasmid pBM527-2, complete sequence	49887-49916	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	MN783744	Klebsiella oxytoca plasmid pFDL-VIM, complete sequence	53506-53535	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NC_012885	Aeromonas hydrophila plasmid pRA1, complete sequence	6505-6534	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_CP042536	Citrobacter freundii strain E51 plasmid pE51_002, complete sequence	5535-5564	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_CP034714	Salmonella enterica subsp. enterica serovar Mikawasima strain RSE15 plasmid pRSE15, complete sequence	5534-5563	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_CP012168	Enterobacter hormaechei subsp. steigerwaltii strain 34998 plasmid p34998-239.973kb, complete sequence	228661-228690	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	MN783743	Escherichia coli plasmid pGA_VIM, complete sequence	64763-64792	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_CP034084	Klebsiella pneumoniae subsp. pneumoniae strain R210-2 plasmid pR210-2-VIM, complete sequence	5538-5567	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_MH220284	Aeromonas sp. pRIVM0001_VIM-1 plasmid pRIVM0001_VIM-1_171012_B12, complete sequence	5494-5523	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_MG228427	Kluyvera cryocrescens strain BO64W plasmid pKC-BO-N1-VIM, complete sequence	5538-5567	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_MG550958	Escherichia coli strain G3216 plasmid pG3216.2, complete sequence	38131-38160	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_MH325469	Enterobacter hormaechei strain Ec13 plasmid pEc13, complete sequence	5811-5840	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_MH325468	Enterobacter hormaechei strain Ec09 plasmid pEc09, complete sequence	5811-5840	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_MH594478	Citrobacter freundii strain AA593 plasmid pIBAC_Incx3_A/C, complete sequence	30452-30481	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_MH594477	Citrobacter freundii strain AA535 plasmid pIBAC_IncA/C, complete sequence	31209-31238	8	0.733
CP025221_5	5.13\|2722228\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2722228-2722257	30	NZ_MG053108	Citrobacter freundii strain 33587 plasmid pCf587, complete sequence	6505-6534	8	0.733
CP025221_5	5.9\|2721964\|30\|CP025221\|CRISPRCasFinder,CRT,PILER-CR	2721964-2721993	30	JQ680352	Unidentified phage clone 1013_scaffold1713 genomic sequence	5412-5441	9	0.7

1. spacer 5.5|2721699|31|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to KJ094022 (Listeria phage LP-030-3, complete genome) position: , mismatch: 0, identity: 1.0

tcgaatgtgtaagcttctgagtaacctagca	CRISPR spacer
tcgaatgtgtaagcttctgagtaacctagca	Protospacer
*******************************

2. spacer 5.6|2721766|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 0, identity: 1.0

taacctttaaaattaaattgaaggtgcgga	CRISPR spacer
taacctttaaaattaaattgaaggtgcgga	Protospacer
******************************

3. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NC_003216 (Listeria phage A118, complete genome) position: , mismatch: 0, identity: 1.0

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
tacatcgctaccaatcaatccgctattaag	Protospacer
******************************

4. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to AJ242593 (Bacteriophage A118 complete genome) position: , mismatch: 0, identity: 1.0

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
tacatcgctaccaatcaatccgctattaag	Protospacer
******************************

5. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to KJ094022 (Listeria phage LP-030-3, complete genome) position: , mismatch: 0, identity: 1.0

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
tacatcgctaccaatcaatccgctattaag	Protospacer
******************************

6. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to MN172529 (Listeria phage LP-039, complete genome) position: , mismatch: 0, identity: 1.0

atctatattatcatacgtcaaggaagggta	CRISPR spacer
atctatattatcatacgtcaaggaagggta	Protospacer
******************************

7. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to MT668624 (Listeria phage LP-Mix_6.2, complete genome) position: , mismatch: 0, identity: 1.0

atctatattatcatacgtcaaggaagggta	CRISPR spacer
atctatattatcatacgtcaaggaagggta	Protospacer
******************************

8. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NC_025440 (Listeria phage WIL-1, complete genome) position: , mismatch: 0, identity: 1.0

atctatattatcatacgtcaaggaagggta	CRISPR spacer
atctatattatcatacgtcaaggaagggta	Protospacer
******************************

9. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NC_047872 (Listeria phage LMTA-94, complete genome) position: , mismatch: 0, identity: 1.0

atctatattatcatacgtcaaggaagggta	CRISPR spacer
atctatattatcatacgtcaaggaagggta	Protospacer
******************************

10. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to KJ591604 (Listeria phage LMTA-148, complete genome) position: , mismatch: 0, identity: 1.0

atctatattatcatacgtcaaggaagggta	CRISPR spacer
atctatattatcatacgtcaaggaagggta	Protospacer
******************************

11. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to KJ591605 (Listeria phage LMTA-57, complete genome) position: , mismatch: 0, identity: 1.0

atctatattatcatacgtcaaggaagggta	CRISPR spacer
atctatattatcatacgtcaaggaagggta	Protospacer
******************************

12. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to KJ094033 (Listeria phage LP-048, complete genome) position: , mismatch: 0, identity: 1.0

atctatattatcatacgtcaaggaagggta	CRISPR spacer
atctatattatcatacgtcaaggaagggta	Protospacer
******************************

13. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to KJ668715 (Listeria phage LMTA-34, partial genome) position: , mismatch: 0, identity: 1.0

atctatattatcatacgtcaaggaagggta	CRISPR spacer
atctatattatcatacgtcaaggaagggta	Protospacer
******************************

14. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NC_042048 (Listeria phage LMTA-34, complete genome) position: , mismatch: 0, identity: 1.0

atctatattatcatacgtcaaggaagggta	CRISPR spacer
atctatattatcatacgtcaaggaagggta	Protospacer
******************************

15. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NC_041862 (Listeria phage LP-064, complete genome) position: , mismatch: 0, identity: 1.0

atctatattatcatacgtcaaggaagggta	CRISPR spacer
atctatattatcatacgtcaaggaagggta	Protospacer
******************************

16. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to JX126918 (Listeria phage LP-125, complete genome) position: , mismatch: 0, identity: 1.0

atctatattatcatacgtcaaggaagggta	CRISPR spacer
atctatattatcatacgtcaaggaagggta	Protospacer
******************************

17. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NC_024360 (Listeria phage LMSP-25, complete genome) position: , mismatch: 0, identity: 1.0

atctatattatcatacgtcaaggaagggta	CRISPR spacer
atctatattatcatacgtcaaggaagggta	Protospacer
******************************

18. spacer 3.3|543540|35|CP025221|PILER-CR,CRT matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 1, identity: 0.971

ctaaaacatccttcactgtatcaactcctttctat	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctat	Protospacer
******************* ***************

19. spacer 3.3|543540|35|CP025221|PILER-CR,CRT matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.971

ctaaaacatccttcactgtatcaactcctttctat	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctat	Protospacer
******************* ***************

20. spacer 3.7|543540|36|CP025221|CRISPRCasFinder matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 1, identity: 0.972

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctata	Protospacer
******************* ****************

21. spacer 3.7|543540|36|CP025221|CRISPRCasFinder matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.972

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctata	Protospacer
******************* ****************

22. spacer 5.5|2721699|31|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to KP399678 (Listeria phage vB_LmoS_293, complete genome) position: , mismatch: 1, identity: 0.968

tcgaatgtgtaagcttctgagtaacctagca	CRISPR spacer
tcgaatgtgtaagcttctgagtaacctagta	Protospacer
*****************************.*

23. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to MT438761 (Listeria virus P61, complete genome) position: , mismatch: 1, identity: 0.967

atctatattatcatacgtcaaggaagggta	CRISPR spacer
gtctatattatcatacgtcaaggaagggta	Protospacer
.*****************************

24. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to MT178766 (Listeria virus P100plus, complete genome) position: , mismatch: 1, identity: 0.967

atctatattatcatacgtcaaggaagggta	CRISPR spacer
gtctatattatcatacgtcaaggaagggta	Protospacer
.*****************************

25. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to DQ003638 (Listeria phage A511, complete genome) position: , mismatch: 1, identity: 0.967

atctatattatcatacgtcaaggaagggta	CRISPR spacer
gtctatattatcatacgtcaaggaagggta	Protospacer
.*****************************

26. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to MT178767 (Listeria virus P200, complete genome) position: , mismatch: 1, identity: 0.967

atctatattatcatacgtcaaggaagggta	CRISPR spacer
gtctatattatcatacgtcaaggaagggta	Protospacer
.*****************************

27. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to DQ004855 (Listeria bacteriophage P100, complete genome) position: , mismatch: 1, identity: 0.967

atctatattatcatacgtcaaggaagggta	CRISPR spacer
gtctatattatcatacgtcaaggaagggta	Protospacer
.*****************************

28. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to MN128594 (Listeria phage LP-066, complete genome) position: , mismatch: 1, identity: 0.967

atctatattatcatacgtcaaggaagggta	CRISPR spacer
gtctatattatcatacgtcaaggaagggta	Protospacer
.*****************************

29. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to MK792752 (UNVERIFIED: Listera phage vB-LmoM-SH3-3, complete genome) position: , mismatch: 1, identity: 0.967

atctatattatcatacgtcaaggaagggta	CRISPR spacer
gtctatattatcatacgtcaaggaagggta	Protospacer
.*****************************

30. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to KJ094030 (Listeria phage LP-083-2, complete genome) position: , mismatch: 1, identity: 0.967

atctatattatcatacgtcaaggaagggta	CRISPR spacer
gtctatattatcatacgtcaaggaagggta	Protospacer
.*****************************

31. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to JQ797329 (Listeria phage vB_LmoM_AG20, complete genome) position: , mismatch: 1, identity: 0.967

atctatattatcatacgtcaaggaagggta	CRISPR spacer
gtctatattatcatacgtcaaggaagggta	Protospacer
.*****************************

32. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to KJ535721 (Listeria phage List-36, complete genome) position: , mismatch: 1, identity: 0.967

atctatattatcatacgtcaaggaagggta	CRISPR spacer
gtctatattatcatacgtcaaggaagggta	Protospacer
.*****************************

33. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to KJ094031 (Listeria phage LP-124, complete genome) position: , mismatch: 1, identity: 0.967

atctatattatcatacgtcaaggaagggta	CRISPR spacer
gtctatattatcatacgtcaaggaagggta	Protospacer
.*****************************

34. spacer 3.1|543411|37|CP025221|PILER-CR,CRT matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.946

tttatttctcctacgcttttcttatttctgtaaataa	CRISPR spacer
tttatttctcctgcgcttttcttatttttgtaaataa	Protospacer
************.**************.*********

35. spacer 3.3|543540|35|CP025221|PILER-CR,CRT matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.943

ctaaaacatccttcactgtatcaactcctttctat	CRISPR spacer
ctaaaacatccttcactatctcaactcctttctat	Protospacer
*****************.* ***************

36. spacer 3.7|543540|36|CP025221|CRISPRCasFinder matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.944

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactatctcaactcctttctata	Protospacer
*****************.* ****************

37. spacer 5.2|2721501|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to KJ094028 (Listeria phage LP-083-1 contig 2, partial genome) position: , mismatch: 2, identity: 0.933

accgaagtaggttagggtatcgccgatttt	CRISPR spacer
tccgaaataggttagggtatcgccgatttt	Protospacer
 *****.***********************

38. spacer 5.2|2721501|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to DQ003641 (Listeria phage P35, complete genome) position: , mismatch: 2, identity: 0.933

accgaagtaggttagggtatcgccgatttt	CRISPR spacer
tccgaaataggttagggtatcgccgatttt	Protospacer
 *****.***********************

39. spacer 5.5|2721699|31|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to MH341452 (Listeria phage PSU-VKH-LP040, complete genome) position: , mismatch: 2, identity: 0.935

tcgaatgtgtaagcttctgagtaacctagca	CRISPR spacer
tcaaacgtgtaagcttctgagtaacctagca	Protospacer
**.**.*************************

40. spacer 5.5|2721699|31|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to DQ003637 (Listeria phage A500, complete genome) position: , mismatch: 2, identity: 0.935

tcgaatgtgtaagcttctgagtaacctagca	CRISPR spacer
tcaaacgtgtaagcttctgagtaacctagca	Protospacer
**.**.*************************

41. spacer 5.6|2721766|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NC_003216 (Listeria phage A118, complete genome) position: , mismatch: 2, identity: 0.933

taacctttaaaattaaattgaaggtgcgga	CRISPR spacer
tagcctttataattaaattgaaggtgcgga	Protospacer
**.****** ********************

42. spacer 5.6|2721766|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to AJ242593 (Bacteriophage A118 complete genome) position: , mismatch: 2, identity: 0.933

taacctttaaaattaaattgaaggtgcgga	CRISPR spacer
tagcctttataattaaattgaaggtgcgga	Protospacer
**.****** ********************

43. spacer 5.6|2721766|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to X85008 (Bacteriophage A118 hol118 and ply118 genes) position: , mismatch: 2, identity: 0.933

taacctttaaaattaaattgaaggtgcgga	CRISPR spacer
tagcctttataattaaattgaaggtgcgga	Protospacer
**.****** ********************

44. spacer 3.5|543411|38|CP025221|CRISPRCasFinder matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 3, identity: 0.921

tttatttctcctacgcttttcttatttctgtaaataag	CRISPR spacer
tttatttctcctgcgcttttcttatttttgtaaataaa	Protospacer
************.**************.*********.

45. spacer 5.5|2721699|31|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NC_003216 (Listeria phage A118, complete genome) position: , mismatch: 4, identity: 0.871

tcgaatgtgtaagcttctgagtaacctagca	CRISPR spacer
tcgaatgtgtaagcttccgaataacctaaaa	Protospacer
*****************.**.*******. *

46. spacer 5.5|2721699|31|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to AJ242593 (Bacteriophage A118 complete genome) position: , mismatch: 4, identity: 0.871

tcgaatgtgtaagcttctgagtaacctagca	CRISPR spacer
tcgaatgtgtaagcttccgaataacctaaaa	Protospacer
*****************.**.*******. *

47. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to MN693541 (Marine virus AFVG_25M436, complete genome) position: , mismatch: 5, identity: 0.833

-tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ataca-ggttaccaatcaaaccgctattaac	Protospacer
 ****  *.********** **********

48. spacer 5.14|2722294|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to MK327943 (Escherichia phage vB_EcoM_G53, complete genome) position: , mismatch: 6, identity: 0.8

atctatattatcatacgtcaaggaagggta	CRISPR spacer
gtctatagtatcatacctcaaggagaagta	Protospacer
.****** ******** *******...***

49. spacer 5.1|2721435|30|CP025221|CRISPRCasFinder,CRT matches to MK813941 (Aeromonas phage 4_L372XY, complete genome) position: , mismatch: 7, identity: 0.767

ttcgtccaatgtacctcgccttttttgtct	CRISPR spacer
taatttcaatgtacctcgccaattttgtcg	Protospacer
*   *.**************  *******

50. spacer 5.8|2721898|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NC_041887 (Rhodococcus phage Weasels2, complete genome) position: , mismatch: 7, identity: 0.767

tcatatattatgaatatcgagatagtgttc	CRISPR spacer
ttctatattatgaagatcgaaatagttatg	Protospacer
*. *********** *****.*****  *

51. spacer 5.9|2721964|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NC_015498 (Glaciecola sp. 4H-3-7+YE-5 plasmid pGLAAG01, complete sequence) position: , mismatch: 7, identity: 0.767

gttttctattttggtgactttagtactttt	CRISPR spacer
gccttctattttagtgactttagtagtgaa	Protospacer
*..*********.************ *

52. spacer 5.11|2722096|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053711 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.767

tattcgatctatcggacgtgtcgacattat	CRISPR spacer
gattcgatctagcggacgtgacgacacctc	Protospacer
 ********** ******** *****.. .

53. spacer 5.11|2722096|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053711 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.767

tattcgatctatcggacgtgtcgacattat	CRISPR spacer
gattcgatctagcggacgtgacgacacctc	Protospacer
 ********** ******** *****.. .

54. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042479 (Citrobacter freundii strain C50 plasmid pC50_001, complete sequence) position: , mismatch: 7, identity: 0.767

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcaca	Protospacer
 .**.*********** *********.* .

55. spacer 5.6|2721766|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP043436 (Campylobacter fetus subsp. venerealis NCTC 10354 plasmid p3226, complete sequence) position: , mismatch: 8, identity: 0.733

taacctttaaaattaaattgaaggtgcgga	CRISPR spacer
caacctttaaaattaaatttaaagaaatta	Protospacer
.****************** **.* .   *

56. spacer 5.6|2721766|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016721 (Lactococcus lactis subsp. lactis strain UC11 plasmid pUC11B, complete sequence) position: , mismatch: 8, identity: 0.733

taacctttaaaattaaattgaaggtgcgga	CRISPR spacer
aagaatttaaaattaaatagaaggtgataa	Protospacer
 *.  ************* *******  .*

57. spacer 5.6|2721766|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016727 (Lactococcus lactis subsp. lactis strain UC08 plasmid pUC08B, complete sequence) position: , mismatch: 8, identity: 0.733

taacctttaaaattaaattgaaggtgcgga	CRISPR spacer
aagaatttaaaattaaatagaaggtgataa	Protospacer
 *.  ************* *******  .*

58. spacer 5.6|2721766|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP008809 (Campylobacter fetus subsp. fetus 04/554 plasmid pCFF04554, complete sequence) position: , mismatch: 8, identity: 0.733

taacctttaaaattaaattgaaggtgcgga	CRISPR spacer
caacctttaaaattaaatttaaagaaatta	Protospacer
.****************** **.* .   *

59. spacer 5.6|2721766|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP008812 (Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-2, complete sequence) position: , mismatch: 8, identity: 0.733

taacctttaaaattaaattgaaggtgcgga	CRISPR spacer
caacctttaaaattaaatttaaagaaatta	Protospacer
.****************** **.* .   *

60. spacer 5.6|2721766|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018792 (Campylobacter sp. RM8964 plasmid pVIC8964, complete sequence) position: , mismatch: 8, identity: 0.733

taacctttaaaattaaattgaaggtgcgga	CRISPR spacer
caacctttaaaattaaatttaaagaaatta	Protospacer
.****************** **.* .   *

61. spacer 5.6|2721766|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016699 (Lactococcus lactis subsp. lactis strain 275 plasmid p275A, complete sequence) position: , mismatch: 8, identity: 0.733

taacctttaaaattaaattgaaggtgcgga	CRISPR spacer
aagaatttaaaattaaatagaaggtgacaa	Protospacer
 *.  ************* *******  .*

62. spacer 5.6|2721766|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018794 (Campylobacter sp. RM12175 plasmid pVIC12175-1, complete sequence) position: , mismatch: 8, identity: 0.733

taacctttaaaattaaattgaaggtgcgga	CRISPR spacer
caacctttaaaattaaatttaaagaaatta	Protospacer
.****************** **.* .   *

63. spacer 5.6|2721766|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to KC699836 (Bacillus phage SIOphi, partial genome) position: , mismatch: 8, identity: 0.733

taacctttaaaattaaattgaaggtgcgga	CRISPR spacer
tccaacttaaatttaaattgaaagtgcggg	Protospacer
*    .***** **********.******.

64. spacer 5.9|2721964|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015799 (Borrelia mayonii strain MN14-1539 plasmid cp32-13, complete sequence) position: , mismatch: 8, identity: 0.733

gttttctattttggtgactttagtactttt	CRISPR spacer
gaaaataatgttggtgactttattactttt	Protospacer
*    . ** ************ *******

65. spacer 5.11|2722096|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NC_014120 (Paraburkholderia sp. CCGE1002 plasmid pBC201, complete sequence) position: , mismatch: 8, identity: 0.733

tattcgatctatcggacgtgtcgacattat	CRISPR spacer
ttttcgatctatcggacgtggcgctgggaa	Protospacer
* ****************** ** ..  *

66. spacer 5.12|2722162|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NC_015427 (Clostridium botulinum BKT015925 plasmid p4BKT015925, complete sequence) position: , mismatch: 8, identity: 0.733

tattgactcggaaatgaaaacaaaaggtca	CRISPR spacer
taaatcttcggaaataaaaacaaaaggttg	Protospacer
**    .********.************..

67. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022274 (Citrobacter freundii strain 18-1 plasmid pA18-1, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

68. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010360 (Enterobacter roggenkampii strain 35734 plasmid p35734-141.404kb, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

69. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP041048 (Citrobacter sp. CF971 plasmid pBM527-2, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

70. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to MN783744 (Klebsiella oxytoca plasmid pFDL-VIM, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

71. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NC_012885 (Aeromonas hydrophila plasmid pRA1, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

72. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042536 (Citrobacter freundii strain E51 plasmid pE51_002, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

73. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034714 (Salmonella enterica subsp. enterica serovar Mikawasima strain RSE15 plasmid pRSE15, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

74. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012168 (Enterobacter hormaechei subsp. steigerwaltii strain 34998 plasmid p34998-239.973kb, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

75. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to MN783743 (Escherichia coli plasmid pGA_VIM, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

76. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034084 (Klebsiella pneumoniae subsp. pneumoniae strain R210-2 plasmid pR210-2-VIM, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

77. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MH220284 (Aeromonas sp. pRIVM0001_VIM-1 plasmid pRIVM0001_VIM-1_171012_B12, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

78. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MG228427 (Kluyvera cryocrescens strain BO64W plasmid pKC-BO-N1-VIM, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

79. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MG550958 (Escherichia coli strain G3216 plasmid pG3216.2, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

80. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MH325469 (Enterobacter hormaechei strain Ec13 plasmid pEc13, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

81. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MH325468 (Enterobacter hormaechei strain Ec09 plasmid pEc09, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

82. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MH594478 (Citrobacter freundii strain AA593 plasmid pIBAC_Incx3_A/C, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

83. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MH594477 (Citrobacter freundii strain AA535 plasmid pIBAC_IncA/C, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

84. spacer 5.13|2722228|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MG053108 (Citrobacter freundii strain 33587 plasmid pCf587, complete sequence) position: , mismatch: 8, identity: 0.733

tacatcgctaccaatcaatccgctattaag	CRISPR spacer
ggcaccgctaccaatccatccgctatcgca	Protospacer
 .**.*********** *********.. .

85. spacer 5.9|2721964|30|CP025221|CRISPRCasFinder,CRT,PILER-CR matches to JQ680352 (Unidentified phage clone 1013_scaffold1713 genomic sequence) position: , mismatch: 9, identity: 0.7

gttttctattttggtgactttagtactttt	CRISPR spacer
cctttctattttggtgagtttagtgaccca	Protospacer
 .*************** ******. ...

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

118347 : 124873

Listeria_phage(33.33%)

tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVV08450.1\|118347_118800_-	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	4.0e-31	47.9
AVV08451.1\|118805_119141_-	XRE family transcriptional regulator	A0A2H4JAR9	uncultured_Caudovirales_phage	4.0e-20	52.5
AVV08452.1\|119357_119786_+	hypothetical protein	NA	NA	NA	NA
AVV08453.1\|119797_120214_+	hypothetical protein	A8ASQ1	Listeria_phage	1.3e-20	39.3
AVV08454.1\|120492_120882_+	DUF5072 domain-containing protein	NA	NA	NA	NA
AVV08455.1\|120894_121407_+\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	1.2e-47	62.7
AVV08456.1\|121454_121757_+	segregation and condensation protein B	NA	NA	NA	NA
AVV08457.1\|121798_122203_+	phenylalanine racemase	NA	NA	NA	NA
AVV08458.1\|122189_124058_+	hypothetical protein	A0A097PAU2	Streptococcus_pyogenes_phage	1.7e-19	45.3
AVV08459.1\|124054_124873_+\|tail	phage tail family protein	A0A060AFE1	Staphylococcus_phage	4.2e-39	35.0

DBSCAN-SWA_2

676742 : 733304

Listeria_phage(45.71%)

transposase,terminase,tail,capsid,integrase,holin,protease,head,portal

attL 709342:709365|attR 712139:712162

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVV08959.1\|676742_677894_-\|integrase	site-specific integrase	A8ATX2	Listeria_phage	3.4e-87	46.3
AVV08960.1\|677915_678629_-	hypothetical protein	NA	NA	NA	NA
AVV08961.1\|678683_679184_-	hypothetical protein	A0A1S7FYX8	Listeria_phage	3.2e-13	31.9
AVV08962.1\|679196_679523_-	XRE family transcriptional regulator	Q0H244	Geobacillus_phage	1.6e-13	47.1
AVV08963.1\|679697_679889_+	XRE family transcriptional regulator	Q0H243	Geobacillus_phage	8.1e-10	57.6
AVV08964.1\|679986_680313_+	DUF771 domain-containing protein	A0A2H4J474	uncultured_Caudovirales_phage	4.9e-15	41.1
AVV08965.1\|680485_681400_+	hypothetical protein	A0A1W6JNI1	Staphylococcus_phage	2.3e-54	51.9
AVV08966.1\|681401_681758_+	MerR family transcriptional regulator	NA	NA	NA	NA
AVV08967.1\|681754_682171_+	hypothetical protein	NA	NA	NA	NA
AVV11234.1\|682428_683415_+	DNA cytosine methyltransferase	H7BVD3	unidentified_phage	7.1e-49	37.4
AVV08968.1\|683411_683957_+	DUF1642 domain-containing protein	A0A0B5D0I5	Listeria_phage	6.5e-52	58.6
AVV08969.1\|683974_684400_+	hypothetical protein	A0A059T6G6	Listeria_phage	7.0e-38	80.7
AVV08970.1\|684503_684887_+	preprotein translocase subunit YajC	A8ATZ3	Listeria_phage	5.4e-45	77.2
AVV08971.1\|684907_685156_+	DUF3850 domain-containing protein	A0A059T7N3	Listeria_phage	3.8e-28	84.0
AVV08972.1\|685155_685737_+	DUF3310 domain-containing protein	A0A059T5J6	Listeria_phage	1.2e-75	75.8
AVV08973.1\|685736_686216_+	single-stranded DNA-binding protein	A8ASP5	Listeria_phage	1.5e-68	81.9
AVV08974.1\|686269_686461_+	hypothetical protein	NA	NA	NA	NA
AVV08975.1\|686521_687040_+	RNA polymerase subunit sigma	NA	NA	NA	NA
AVV08976.1\|687036_687579_+\|integrase	site-specific integrase	H0USV4	Bacillus_phage	4.3e-48	53.3
AVV08977.1\|687862_688189_+	hypothetical protein	NA	NA	NA	NA
AVV08978.1\|688185_688548_+	HNH endonuclease	A0A075M5R4	Enterococcus_phage	5.5e-15	46.2
AVV08979.1\|688642_689170_+\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	6.1e-31	46.7
AVV08980.1\|689138_690890_+\|terminase	terminase large subunit	A0A2H4JCI4	uncultured_Caudovirales_phage	4.1e-156	50.7
AVV08981.1\|690896_691097_+	DUF1056 domain-containing protein	NA	NA	NA	NA
AVV08982.1\|691099_692335_+\|portal	phage portal protein	A0A2H4JAR2	uncultured_Caudovirales_phage	3.6e-82	42.1
AVV08983.1\|692331_692898_+\|head,protease	HK97 family phage prohead protease	A0A1D6Z2A7	Staphylococcus_phage	1.0e-44	52.2
AVV08984.1\|692955_694131_+\|capsid	phage major capsid protein	A0A060AI54	Enterococcus_phage	2.2e-44	38.1
AVV08985.1\|694179_694518_+\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JB77	uncultured_Caudovirales_phage	1.1e-12	37.8
AVV08986.1\|694487_694808_+\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
AVV08987.1\|694801_695167_+	hypothetical protein	NA	NA	NA	NA
AVV08988.1\|695169_695568_+	hypothetical protein	NA	NA	NA	NA
AVV08989.1\|695589_696165_+\|tail	phage tail protein	M1PRQ7	Streptococcus_phage	6.0e-32	41.8
AVV08990.1\|696254_696602_+	hypothetical protein	NA	NA	NA	NA
AVV08991.1\|696798_700998_+\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	1.6e-12	33.0
AVV08992.1\|700990_703234_+\|tail	phage tail protein	A0A059T682	Listeria_phage	1.2e-56	29.4
AVV08993.1\|703239_705531_+	hypothetical protein	A0A059T7Y6	Listeria_phage	8.3e-133	37.7
AVV08994.1\|705523_706588_+	hypothetical protein	A0A059T7R4	Listeria_phage	1.7e-109	58.5
AVV08995.1\|706635_707079_+	hypothetical protein	A0A059T6F6	Listeria_phage	6.8e-76	100.0
AVV08996.1\|707057_707474_+	hypothetical protein	A0A059T5F5	Listeria_phage	1.1e-43	100.0
AVV08997.1\|707494_707761_+\|holin	phage holin	A0A059T684	Listeria_phage	1.0e-39	96.6
AVV08998.1\|707757_708585_+	N-acetylmuramoyl-L-alanine amidase	Q8W5Y8	Listeria_phage	1.7e-75	77.8
AVV08999.1\|708658_709105_-	hypothetical protein	Q9T196	Listeria_phage	2.4e-65	94.2
709342:709365	attL	NA	NA	NA	NA
AVV09000.1\|709812_710094_-\|integrase	integrase	NA	NA	NA	NA
AVV09001.1\|710443_711358_+	peptidase	NA	NA	NA	NA
AVV09002.1\|711357_711717_+	DUF3221 domain-containing protein	NA	NA	NA	NA
AVV09003.1\|712248_712782_+	transcriptional regulator	NA	NA	NA	NA
712139:712162	attR	NA	NA	NA	NA
AVV09004.1\|712845_713763_+	aldo/keto reductase	NA	NA	NA	NA
AVV09005.1\|714028_715909_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	4.9e-107	38.4
AVV09006.1\|716004_716733_+	hypothetical protein	NA	NA	NA	NA
AVV09007.1\|716874_717525_+	transaldolase	A0A0E3HJ81	Synechococcus_phage	1.5e-15	27.6
AVV09008.1\|717564_719385_-	LTA synthase family protein	W6LM83	Streptococcus_phage	2.2e-48	28.4
AVV09009.1\|719619_721011_+	amino acid transporter	NA	NA	NA	NA
AVV09010.1\|721100_721940_+	glyoxalase	NA	NA	NA	NA
AVV09011.1\|722022_722307_-	hypothetical protein	NA	NA	NA	NA
AVV09012.1\|722404_723355_+	magnesium transporter CorA family protein	NA	NA	NA	NA
AVV09013.1\|723378_724020_+	GntR family transcriptional regulator	NA	NA	NA	NA
AVV09014.1\|724062_726753_+	YhgE/Pip domain-containing protein	NA	NA	NA	NA
AVV09015.1\|726798_727446_+	GntR family transcriptional regulator	NA	NA	NA	NA
AVV09016.1\|727454_727991_-	N-acetyltransferase	NA	NA	NA	NA
AVV09017.1\|729088_729298_+	hypothetical protein	NA	NA	NA	NA
AVV09018.1\|729365_730073_+	serine/threonine protein phosphatase	A0A249Y183	Enterococcus_phage	3.8e-20	28.2
AVV09019.1\|730116_730680_-	DUF420 domain-containing protein	NA	NA	NA	NA
AVV09020.1\|730799_731216_+	hypothetical protein	NA	NA	NA	NA
AVV09021.1\|731267_731903_+	endonuclease III domain-containing protein	NA	NA	NA	NA
AVV09022.1\|731892_732789_-	Rgg family transcriptional regulator	NA	NA	NA	NA
AVV09023.1\|733019_733304_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1158245 : 1165668

Hokovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVV09455.1\|1158245_1158629_+	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	1.4e-16	40.7
AVV09456.1\|1158650_1159634_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	4.1e-12	34.6
AVV09457.1\|1159648_1160662_+	glycosyl transferase	A0A1V0SAH6	Catovirus	7.9e-11	32.0
AVV09458.1\|1160870_1162361_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	9.5e-114	49.7
AVV09459.1\|1162372_1163197_+	NAD(+) synthetase	G3MA24	Bacillus_virus	9.7e-68	52.6
AVV09460.1\|1163209_1163518_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
AVV09461.1\|1163578_1163983_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
AVV09462.1\|1164111_1165668_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	2.3e-17	28.1

DBSCAN-SWA_4

1277721 : 1358488

102

Listeria_phage(82.26%)

terminase,tail,capsid,tRNA,integrase,holin,protease,head,portal

attL 1277605:1277621|attR 1320843:1320859

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1277605:1277621	attL	NA	NA	NA	NA
AVV09585.1\|1277721_1278876_-\|integrase	site-specific integrase	A8ATC7	Listeria_phage	3.4e-204	92.4
AVV09586.1\|1279010_1279445_-	hypothetical protein	Q8W5Y2	Listeria_phage	6.5e-55	81.2
AVV09587.1\|1279460_1280030_-	DUF4352 domain-containing protein	R4IBV3	Listeria_phage	9.8e-11	92.3
AVV09588.1\|1280080_1280533_-	ImmA/IrrE family metallo-endopeptidase	R4IBK9	Listeria_phage	1.1e-78	90.7
AVV09589.1\|1280549_1280873_-	XRE family transcriptional regulator	A0A059T6G1	Listeria_phage	4.7e-34	69.2
AVV09590.1\|1281502_1281706_-	hypothetical protein	NA	NA	NA	NA
AVV09591.1\|1281772_1281964_+	XRE family transcriptional regulator	A0A059T5F8	Listeria_phage	5.4e-22	87.1
AVV09592.1\|1281985_1282228_+	hypothetical protein	A8ATD2	Listeria_phage	3.9e-41	93.8
AVV09593.1\|1282230_1282416_+	hypothetical protein	A8ATD3	Listeria_phage	1.1e-27	95.1
AVV09594.1\|1282936_1283119_+	hypothetical protein	NA	NA	NA	NA
AVV09595.1\|1283115_1283571_+	class I SAM-dependent methyltransferase	A8ATY8	Listeria_phage	1.5e-81	90.7
AVV09596.1\|1283758_1284043_+	hypothetical protein	A0A059T7N1	Listeria_phage	2.3e-45	94.7
AVV09597.1\|1284039_1284249_+	hypothetical protein	A8ASN7	Listeria_phage	5.7e-25	89.9
AVV09598.1\|1284245_1284845_+	DUF1642 domain-containing protein	Q8W5X2	Listeria_phage	1.7e-58	60.5
AVV09599.1\|1284847_1285042_+	hypothetical protein	A0A0B5CU49	Listeria_phage	2.4e-25	93.5
AVV09600.1\|1285044_1285488_+	hypothetical protein	NA	NA	NA	NA
AVV09601.1\|1285484_1285664_+	hypothetical protein	A0A059T5G0	Listeria_phage	1.7e-22	89.8
AVV09602.1\|1285722_1286316_+	hypothetical protein	A0A060AFJ6	Listeria_phage	2.5e-41	76.0
AVV09603.1\|1286419_1286635_+	hypothetical protein	NA	NA	NA	NA
AVV09604.1\|1286631_1286841_+	hypothetical protein	A0A059T6C7	Listeria_phage	6.6e-13	59.1
AVV09605.1\|1286841_1287171_+	hypothetical protein	A8ATE1	Listeria_phage	1.1e-57	100.0
AVV09606.1\|1287167_1287440_+	hypothetical protein	A8ATE2	Listeria_phage	2.0e-46	100.0
AVV09607.1\|1287436_1287655_+	hypothetical protein	NA	NA	NA	NA
AVV09608.1\|1287651_1288086_+	hypothetical protein	A8ATS7	Listeria_phage	2.5e-38	52.8
AVV09609.1\|1288288_1288672_+	hypothetical protein	A8ATE8	Listeria_phage	5.3e-61	92.9
AVV09610.1\|1288673_1289153_+	hypothetical protein	R4IBM0	Listeria_phage	7.6e-57	76.7
AVV09611.1\|1289172_1289862_+	DNA-binding protein	R4IDY8	Listeria_phage	2.8e-129	98.3
AVV09612.1\|1289925_1291182_+	ATP-dependent helicase	R4IBK4	Listeria_phage	6.0e-218	94.5
AVV09613.1\|1291206_1291689_+	hypothetical protein	A8ATF2	Listeria_phage	2.7e-86	98.1
AVV09614.1\|1291711_1294000_+	DNA primase	A8ATF3	Listeria_phage	0.0e+00	93.9
AVV09615.1\|1294333_1294651_+	VRR-NUC domain-containing protein	A8ATF4	Listeria_phage	9.2e-51	95.1
AVV09616.1\|1294652_1294865_+	hypothetical protein	NA	NA	NA	NA
AVV11244.1\|1295454_1295994_+	DUF3310 domain-containing protein	A8ATF5	Listeria_phage	1.2e-71	74.9
AVV09617.1\|1295990_1296269_+	hypothetical protein	NA	NA	NA	NA
AVV09618.1\|1296504_1296732_+	hypothetical protein	NA	NA	NA	NA
AVV09619.1\|1296744_1297170_+	hypothetical protein	A0A059T6H4	Listeria_phage	8.0e-74	100.0
AVV09620.1\|1297267_1298011_+	DUF559 domain-containing protein	NA	NA	NA	NA
AVV09621.1\|1298257_1298584_+	hypothetical protein	A0A059T5G5	Listeria_phage	2.2e-55	100.0
AVV09622.1\|1298583_1298898_+	HNH endonuclease	A8ATF8	Listeria_phage	5.0e-57	98.1
AVV11245.1\|1298947_1299304_+	hypothetical protein	A8AT94	Listeria_phage	2.6e-46	98.0
AVV09623.1\|1299300_1300944_+\|terminase	terminase large subunit	A0A059T7Q8	Listeria_phage	0.0e+00	98.5
AVV09624.1\|1300955_1302086_+\|portal	phage portal protein	A8AT96	Listeria_phage	3.7e-203	92.8
AVV09625.1\|1302082_1302889_+\|protease	Clp protease ClpP	A0A059T5F2	Listeria_phage	3.8e-133	93.3
AVV09626.1\|1302915_1304067_+\|capsid	phage major capsid protein	A8AT98	Listeria_phage	1.6e-214	99.5
AVV09627.1\|1304253_1304553_+	hypothetical protein	A8ATA0	Listeria_phage	5.3e-48	100.0
AVV09628.1\|1304536_1304902_+\|head,tail	phage head-tail adapter protein	A8ATA1	Listeria_phage	1.3e-64	100.0
AVV09629.1\|1304898_1305300_+	hypothetical protein	A8ATA2	Listeria_phage	2.1e-68	100.0
AVV09630.1\|1305296_1305680_+	DUF3168 domain-containing protein	A8ATA3	Listeria_phage	3.8e-67	100.0
AVV09631.1\|1305701_1306289_+\|tail	phage tail protein	A8ATA4	Listeria_phage	5.8e-107	99.5
AVV09632.1\|1306359_1306692_+	hypothetical protein	A8ATA5	Listeria_phage	1.8e-52	99.1
AVV09633.1\|1306907_1311719_+\|tail	phage tail tape measure protein	A0A059T5F4	Listeria_phage	0.0e+00	70.3
AVV09634.1\|1311706_1313356_+\|tail	phage tail protein	A0A059T682	Listeria_phage	0.0e+00	99.5
AVV09635.1\|1313368_1315663_+	hypothetical protein	A0A059T7Y6	Listeria_phage	0.0e+00	94.0
AVV09636.1\|1315652_1316747_+	carbohydrate-binding protein CenC	A0A059T7R4	Listeria_phage	2.2e-184	87.9
AVV09637.1\|1316794_1317097_+	hypothetical protein	A0A059T5E6	Listeria_phage	1.7e-38	93.0
AVV09638.1\|1317096_1317354_+\|holin	phage holin	A8ATB7	Listeria_phage	3.2e-25	69.0
AVV09639.1\|1317353_1318196_+	peptidase M15	A0A059T7Y8	Listeria_phage	9.5e-127	81.6
AVV09640.1\|1318299_1319298_+	DUF3644 domain-containing protein	A0A0N9RUA4	Staphylococcus_phage	3.9e-71	44.8
AVV09641.1\|1319512_1319719_-	hypothetical protein	A0A059T7Z0	Listeria_phage	1.3e-16	82.8
AVV09642.1\|1320309_1320543_+	hypothetical protein	R4IDW6	Listeria_phage	2.8e-28	78.9
AVV09643.1\|1320539_1320731_+	hypothetical protein	R4IBI5	Listeria_phage	8.9e-25	88.9
AVV09644.1\|1321224_1322583_+	DUF1254 domain-containing protein	NA	NA	NA	NA
1320843:1320859	attR	NA	NA	NA	NA
AVV09645.1\|1322624_1323218_-	hypothetical protein	NA	NA	NA	NA
AVV09646.1\|1323354_1323762_-	VOC family protein	NA	NA	NA	NA
AVV09647.1\|1323926_1324526_+	histidine phosphatase family protein	A0A1X9IGJ2	Lactococcus_phage	2.9e-29	40.5
AVV09648.1\|1324558_1324819_-	hypothetical protein	NA	NA	NA	NA
AVV09649.1\|1324942_1326355_+	RNA helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	4.9e-51	32.1
AVV09650.1\|1326379_1326643_+	DUF3116 domain-containing protein	NA	NA	NA	NA
AVV09651.1\|1326810_1327287_+	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
AVV09652.1\|1327324_1327570_-	hypothetical protein	NA	NA	NA	NA
AVV09653.1\|1327566_1328772_-	MFS transporter	NA	NA	NA	NA
AVV09654.1\|1328768_1328978_-	hypothetical protein	NA	NA	NA	NA
AVV09655.1\|1328976_1329636_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
AVV09656.1\|1329677_1329872_-	hypothetical protein	NA	NA	NA	NA
AVV09657.1\|1329938_1330787_-	YitT family protein	NA	NA	NA	NA
AVV09658.1\|1331405_1332119_+	trehalose operon repressor	NA	NA	NA	NA
AVV09659.1\|1332138_1333797_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
AVV09660.1\|1333815_1335300_-	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
AVV09661.1\|1335415_1335868_+	NUDIX domain-containing protein	NA	NA	NA	NA
AVV09662.1\|1335914_1336379_-	hypothetical protein	NA	NA	NA	NA
AVV09663.1\|1336567_1337446_+	alpha/beta hydrolase	NA	NA	NA	NA
AVV09664.1\|1337465_1338713_-	gamma-glutamyl-phosphate reductase	A0A1X9I5D4	Streptococcus_phage	1.2e-106	51.8
AVV09665.1\|1338696_1339527_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.3e-47	42.4
AVV09666.1\|1339662_1340802_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
AVV09667.1\|1340882_1341278_-	XRE family transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
AVV09668.1\|1341428_1341644_+	XRE family transcriptional regulator	NA	NA	NA	NA
AVV09669.1\|1341762_1342296_+	hypothetical protein	NA	NA	NA	NA
AVV09670.1\|1342313_1342979_+	hypothetical protein	NA	NA	NA	NA
AVV09671.1\|1343240_1344179_+	hypothetical protein	NA	NA	NA	NA
AVV09672.1\|1344293_1345577_+	trigger factor	NA	NA	NA	NA
AVV09673.1\|1345762_1347022_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-145	63.2
AVV09674.1\|1347140_1347707_+	signal peptidase I	NA	NA	NA	NA
AVV09675.1\|1347741_1348311_+	signal peptidase I	NA	NA	NA	NA
AVV09676.1\|1348412_1348955_+	signal peptidase I	NA	NA	NA	NA
AVV09677.1\|1348964_1349828_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
AVV09678.1\|1349824_1350610_+	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	3.0e-26	39.2
AVV09679.1\|1350743_1351604_+	DNA-protecting protein DprA	NA	NA	NA	NA
AVV09680.1\|1351874_1353953_+	type I DNA topoisomerase	A0A1V0SB35	Catovirus	3.2e-107	37.5
AVV09681.1\|1354015_1355320_+\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
AVV09682.1\|1355602_1356505_+	tyrosine recombinase XerC	A0A097EYL9	Mycobacterium_phage	1.2e-13	28.6
AVV09683.1\|1356525_1357065_+	HslU--HslV peptidase proteolytic subunit	NA	NA	NA	NA
AVV09684.1\|1357078_1358488_+\|protease	ATP-dependent protease ATPase subunit HslU	W6AS21	Erwinia_phage	3.7e-43	28.7

DBSCAN-SWA_5

1915039 : 1923325

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVV10189.1\|1915039_1915606_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.1e-25	35.9
AVV10190.1\|1915602_1916652_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	4.6e-62	43.5
AVV10191.1\|1916670_1918098_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
AVV10192.1\|1918082_1920302_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.5e-160	41.4
AVV10193.1\|1920294_1920978_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AVV10194.1\|1920981_1921227_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AVV10195.1\|1921238_1921952_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	2.7e-42	38.7
AVV10196.1\|1922032_1923325_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	33.0

DBSCAN-SWA_6

2582901 : 2590745

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVV10818.1\|2582901_2583873_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4
AVV10819.1\|2583880_2584849_-	gluconeogenesis factor	A1IMD5	Streptococcus_phage	6.7e-68	43.3
AVV10820.1\|2584850_2585726_-	RNase adaptor protein RapZ	A0A0R8VB27	Thermobifida_phage	3.2e-08	29.7
AVV10821.1\|2585833_2587564_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	2.3e-175	54.0
AVV10822.1\|2587605_2588667_-	galactose mutarotase	NA	NA	NA	NA
AVV10823.1\|2588683_2589667_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	2.6e-51	37.2
AVV10824.1\|2589785_2590745_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-88	53.7

DBSCAN-SWA_7

2880020 : 2890051

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVV11107.1\|2880020_2882174_-	DNA topoisomerase III	A0A1X9I6W8	Streptococcus_phage	4.0e-44	34.1
AVV11108.1\|2882197_2883970_-	DNA helicase RecQ	A0A2K9L3P7	Tupanvirus	6.3e-80	37.1
AVV11109.1\|2884130_2885597_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	8.0e-97	40.0
AVV11284.1\|2885619_2885754_+	restriction endonuclease	NA	NA	NA	NA
AVV11110.1\|2885883_2886414_-	ADP-ribose-binding protein	A0A0K1L687	Scale_drop_disease_virus	5.2e-30	50.0
AVV11111.1\|2886471_2888082_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	2.4e-46	29.7
AVV11112.1\|2888260_2888569_+	hypothetical protein	NA	NA	NA	NA
AVV11113.1\|2888596_2890051_+	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	1.9e-50	30.3

Anti-CRISPR protein detection

Acr_ID: CP025221.1|AVV09011.1|722022_722307_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

CP025221.1|AVV09011.1|722022_722307_-|hypothetical-protein

722022_722307_-

94 aa aa

676742-733304

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
CP025221_3	Orphan	3.4\|543604\|36\|CP025221\|PILER-CR,CRT	543604-543639	36	693959-693924	2

1. spacer 3.4|543604|36|CP025221|PILER-CR,CRT matches to CP025221 position: 693959-693924, mismatch: 2

acaataataggatattttggatttgtctgcgttcct	CRISPR spacer
acgataataggatattttggatttgcctgcgttcct	Protospacer
**.**********************.**********

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP025221

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information