CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP028951	Klebsiella aerogenes strain AR_0161 chromosome, complete genome	0 crisprs	RT,DEDDh,cas3,csa3,DinG,WYL	0	0	1	0
CP028952	Klebsiella aerogenes strain AR_0161 plasmid unnamed, complete sequence	0 crisprs	RT	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

3158386 : 3206457

Cronobacter_phage(28.57%)

holin,head,terminase,coat,integrase,tail

attL 3161066:3161081|attR 3212689:3212704

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWD04317.1\|3158386_3159196_-	peptide ABC transporter ATP-binding protein SapF	G3M9Y6	Bacillus_virus	6.1e-14	27.0
AWD04318.1\|3159197_3160190_-	peptide ABC transporter ATP-binding protein SapD	G9BWD6	Planktothrix_phage	1.6e-08	26.1
AWD04319.1\|3160189_3161080_-	peptide ABC transporter permease SapC	NA	NA	NA	NA
3161066:3161081	attL	NA	NA	NA	NA
AWD04320.1\|3161256_3162444_+\|integrase	integrase	K7PGY1	Enterobacteria_phage	3.5e-119	52.4
AWD04321.1\|3162340_3162637_-	hypothetical protein	NA	NA	NA	NA
AWD04322.1\|3162743_3163571_-	hypothetical protein	A0A0U4IID7	Pseudomonas_phage	5.4e-18	25.5
AWD04323.1\|3163796_3164174_-	protein ninX	A0A1P8DTT2	Salmonella_phage	1.7e-19	45.2
AWD04324.1\|3164173_3164395_-	hypothetical protein	Q9ZXI6	Pseudomonas_virus	5.1e-08	46.8
AWD04325.1\|3164391_3164616_-	hypothetical protein	A9YWV3	Burkholderia_phage	2.0e-07	45.0
AWD04326.1\|3164612_3165302_-	hypothetical protein	M1F3E2	Salmonella_phage	1.8e-43	44.9
AWD04327.1\|3165298_3165517_-	hypothetical protein	NA	NA	NA	NA
AWD04328.1\|3165513_3166635_-	site-specific DNA-methyltransferase	A0A1P8DTZ3	Salmonella_phage	4.1e-101	51.8
AWD04329.1\|3166648_3166933_-	hypothetical protein	NA	NA	NA	NA
AWD04330.1\|3166947_3167463_-	single-stranded DNA-binding protein	A0A220NRQ8	Escherichia_phage	3.4e-63	69.6
AWD04331.1\|3167459_3168332_-	hypothetical protein	A0A1B1P9H8	Acinetobacter_phage	2.3e-59	50.6
AWD04332.1\|3168754_3168961_-	cell division inhibitor protein	K7P6H3	Enterobacteria_phage	2.5e-25	76.5
AWD04333.1\|3169232_3169577_-	hypothetical protein	NA	NA	NA	NA
AWD04334.1\|3170030_3170723_-	hypothetical protein	A0A2I6PIE7	Escherichia_phage	1.8e-59	54.1
AWD04335.1\|3170850_3171099_+	transcriptional regulator	A0A2H4FNF3	Salmonella_phage	2.6e-16	52.7
AWD04336.1\|3171195_3171738_+	regulator	M9NZI6	Enterobacteria_phage	7.8e-82	86.1
AWD04337.1\|3171922_3172855_+	replication protein	A0A077KB11	Edwardsiella_phage	2.8e-55	78.7
AWD04338.1\|3172851_3173553_+	Replication protein P	A0A0M3ULE2	Salmonella_phage	1.8e-102	80.0
AWD04339.1\|3173753_3174419_+	hypothetical protein	NA	NA	NA	NA
AWD04340.1\|3174435_3175374_+	hypothetical protein	NA	NA	NA	NA
AWD04341.1\|3175931_3176504_+	hypothetical protein	NA	NA	NA	NA
AWD04342.1\|3176553_3176811_+	DNA polymerase III subunit theta	G8C7V1	Escherichia_phage	9.2e-25	70.1
AWD04343.1\|3176993_3177443_+	recombination protein NinB	Q8VNP6	Enterobacteria_phage	4.1e-36	50.7
AWD04344.1\|3177435_3177606_+	hypothetical protein	K7P7K0	Enterobacteria_phage	1.6e-09	57.4
AWD04345.1\|3177598_3178180_+	protein NinG	E7C9S3	Salmonella_phage	1.2e-40	50.2
AWD04346.1\|3178176_3178317_+	hypothetical protein	NA	NA	NA	NA
AWD04347.1\|3178313_3179003_+	antiterminator	I6PDF8	Cronobacter_phage	2.8e-60	56.2
AWD04348.1\|3179249_3179846_-	hypothetical protein	NA	NA	NA	NA
AWD04349.1\|3179977_3180373_+	hypothetical protein	K7PHB9	Enterobacterial_phage	3.9e-59	92.4
AWD04350.1\|3180359_3180665_+\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	6.8e-43	90.3
AWD04351.1\|3180642_3181185_+	hypothetical protein	A0A0U2I1S0	Escherichia_phage	2.3e-78	73.2
AWD04352.1\|3181181_3181457_+	hypothetical protein	G8C7W1	Escherichia_phage	2.4e-15	52.2
AWD04353.1\|3181446_3181602_+	hypothetical protein	A0A286SGR9	Klebsiella_phage	1.0e-15	82.6
AWD04354.1\|3182227_3182512_-	hypothetical protein	NA	NA	NA	NA
AWD06200.1\|3182721_3182958_+	hypothetical protein	NA	NA	NA	NA
AWD04355.1\|3183623_3183812_+	hypothetical protein	NA	NA	NA	NA
AWD04356.1\|3183815_3184418_+	hypothetical protein	G8C7P2	Escherichia_phage	4.9e-77	81.5
AWD04357.1\|3184417_3185893_+\|terminase	terminase	A0A1W6JNY3	Morganella_phage	2.5e-255	84.7
AWD04358.1\|3185903_3187370_+	DUF1073 domain-containing protein	F1C5D7	Cronobacter_phage	9.0e-157	61.2
AWD04359.1\|3187305_3188301_+\|head	phage head morphogenesis protein	F1C5D8	Cronobacter_phage	9.2e-113	67.3
AWD04360.1\|3188319_3189063_+	hypothetical protein	NA	NA	NA	NA
AWD04361.1\|3189124_3190513_+	DUF2213 domain-containing protein	F1C5D9	Cronobacter_phage	7.7e-150	59.0
AWD04362.1\|3190516_3190957_+	hypothetical protein	F1C5E0	Cronobacter_phage	1.2e-43	64.4
AWD04363.1\|3190968_3192045_+\|coat	phage coat protein	F1C5E1	Cronobacter_phage	8.6e-157	76.8
AWD04364.1\|3192054_3192456_+	hypothetical protein	NA	NA	NA	NA
AWD04365.1\|3192458_3192839_+	hypothetical protein	F1C5E2	Cronobacter_phage	3.1e-29	55.3
AWD04366.1\|3192838_3193012_+	50S ribosomal protein L13	Q5G8X7	Enterobacteria_phage	1.1e-13	57.1
AWD04367.1\|3193011_3193359_+	hypothetical protein	G0ZNE2	Cronobacter_phage	3.5e-35	62.6
AWD04368.1\|3193361_3193802_+	hypothetical protein	A0A1V0E5P5	Salmonella_phage	8.9e-36	53.2
AWD04369.1\|3193798_3194188_+	hypothetical protein	G0ZNE4	Cronobacter_phage	1.3e-38	56.2
AWD04370.1\|3194256_3195009_+	DNA breaking-rejoining protein	G0ZNE6	Cronobacter_phage	2.1e-45	42.6
AWD04371.1\|3195060_3195750_+	hypothetical protein	G0ZNE7	Cronobacter_phage	2.0e-66	54.4
AWD04372.1\|3195954_3196512_+	Rha family transcriptional regulator	A0A088CBJ5	Shigella_phage	1.2e-88	89.3
AWD06201.1\|3196575_3196974_-	hypothetical protein	A0A077K9U2	Edwardsiella_phage	2.3e-14	36.5
AWD04373.1\|3197045_3197909_-	hypothetical protein	NA	NA	NA	NA
AWD04374.1\|3198252_3199233_+	hypothetical protein	I6R977	Salmonella_phage	2.7e-77	71.3
AWD04375.1\|3199341_3199746_+	hypothetical protein	A0A286S1N7	Klebsiella_phage	4.5e-18	42.1
AWD04376.1\|3199806_3202158_+\|tail	phage tail tape measure protein	A0A1B1W284	Salmonella_phage	4.2e-124	49.4
AWD04377.1\|3202360_3202534_-	ATP-NAD kinase	NA	NA	NA	NA
AWD04378.1\|3202702_3203134_+	hypothetical protein	F1C5F0	Cronobacter_phage	1.1e-35	56.1
AWD04379.1\|3203130_3203601_+	hypothetical protein	NA	NA	NA	NA
AWD04380.1\|3203597_3203987_+	hypothetical protein	F1C5F2	Cronobacter_phage	4.8e-33	48.4
AWD04381.1\|3203979_3206457_+\|tail	phage tail protein	F1C5A7	Cronobacter_phage	1.3e-192	43.9
3212689:3212704	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP028952

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

26034 : 47219

Salmonella_phage(28.57%)

transposase,integrase

attL 27377:27393|attR 58710:58726

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWD06293.1\|26034_27039_-\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
AWD06294.1\|27117_30087_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	72.9
27377:27393	attL	NA	NA	NA	NA
AWD06295.1\|30089_30647_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	5.8e-48	81.3
AWD06296.1\|30684_31008_-\|transposase	transposase	NA	NA	NA	NA
AWD06297.1\|30952_31966_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
AWD06298.1\|32118_32859_+	subclass B1 metallo-beta-lactamase IMP-4	NA	NA	NA	NA
AWD06299.1\|32948_34298_-	group II intron reverse transcriptase/maturase	H7BV81	unidentified_phage	3.3e-12	28.3
AWD06300.1\|35037_35370_+	quaternary ammonium compound efflux SMR transporter QacG2	NA	NA	NA	NA
AWD06301.1\|35496_36051_+	aminoglycoside N-acetyltransferase AAC(6')-Ib4	NA	NA	NA	NA
AWD06302.1\|36706_37105_-	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
AWD06303.1\|37179_37530_+	mercury transporter MerT	NA	NA	NA	NA
AWD06304.1\|37542_37818_+	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
AWD06305.1\|37825_38038_+	hypothetical protein	NA	NA	NA	NA
AWD06306.1\|38050_41044_-\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	5.7e-259	47.6
AWD06307.1\|41457_41697_-	methionine repressor-like protein	NA	NA	NA	NA
AWD06308.1\|41794_42409_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	6.6e-37	50.3
AWD06309.1\|42461_42698_-	mercury resistance protein	NA	NA	NA	NA
AWD06310.1\|42694_43060_-	mercuric resistance transcriptional repressor protein MerD	NA	NA	NA	NA
AWD06311.1\|43076_44723_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-39	28.3
AWD06312.1\|44719_44965_-	mercury resistance system transport protein MerF	NA	NA	NA	NA
AWD06313.1\|44967_45243_-	mercuric transporter periplasmic component	NA	NA	NA	NA
AWD06314.1\|45258_45609_-	mercuric ion transporter MerT	NA	NA	NA	NA
AWD06315.1\|45680_46115_+	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
AWD06316.1\|46214_47219_+\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
58710:58726	attR	NA	NA	NA	NA

DBSCAN-SWA_2

58501 : 128326

Escherichia_phage(25.0%)

transposase,integrase

attL 61955:62014|attR 127569:128389

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWD06325.1\|58501_61387_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	5.4e-190	39.8
61955:62014	attL	NA	NA	NA	NA
AWD06326.1\|62007_62712_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AWD06327.1\|62944_63805_+	aminoglycoside N-acetyltransferase AAC(3)-IId	NA	NA	NA	NA
AWD06328.1\|63817_64360_+	tunicamycin resistance protein	NA	NA	NA	NA
AWD06329.1\|64841_65033_-	hypothetical protein	NA	NA	NA	NA
AWD06330.1\|65038_65284_+	hypothetical protein	NA	NA	NA	NA
AWD06331.1\|65334_66471_+	DUF3883 domain-containing protein	NA	NA	NA	NA
AWD06332.1\|66585_67956_+\|transposase	IS1182 family transposase ISCfr1	NA	NA	NA	NA
AWD06333.1\|68776_69637_+	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
AWD06334.1\|72853_73414_-\|transposase	transposase	A0A1B0V7I5	Salmonella_phage	1.1e-59	100.0
AWD06335.1\|73494_73812_-\|transposase	transposase	NA	NA	NA	NA
AWD06336.1\|73750_74764_-\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
AWD06651.1\|75055_75610_+	fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5	NA	NA	NA	NA
AWD06652.1\|75740_76571_+	oxacillin-hydrolyzing class D beta-lactamase OXA-1	NA	NA	NA	NA
AWD06337.1\|76708_77341_+	type B-3 chloramphenicol O-acetyltransferase CatB3	A0A2R8FE91	Brazilian_cedratvirus	4.1e-26	41.2
AWD06338.1\|77425_77878_+	NAD(+)--rifampin ADP-ribosyltransferase Arr-3	NA	NA	NA	NA
AWD06339.1\|78100_78448_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
AWD06340.1\|78441_79281_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
AWD06341.1\|79685_81227_+\|transposase	IS91 family transposase	NA	NA	NA	NA
AWD06342.1\|82177_83419_+	tellurium resistance protein TerF	A0A2D1GNA9	Pseudoalteromonas_phage	8.2e-10	25.5
AWD06343.1\|83446_84097_-	HAD-IB family hydrolase	NA	NA	NA	NA
AWD06344.1\|84702_85719_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	3.7e-186	99.4
AWD06345.1\|85977_86547_+	hypothetical protein	NA	NA	NA	NA
AWD06346.1\|86737_87484_-	hypothetical protein	NA	NA	NA	NA
AWD06347.1\|87550_88309_-	hypothetical protein	NA	NA	NA	NA
AWD06348.1\|88560_89295_-	plasmid SOS inhibition protein A	NA	NA	NA	NA
AWD06349.1\|89925_90525_-	hypothetical protein	NA	NA	NA	NA
AWD06350.1\|91496_92617_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.9e-51	42.4
AWD06351.1\|94208_95747_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	4.1e-277	92.8
AWD06352.1\|95795_96143_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZDM8	Stx2-converting_phage	7.7e-59	95.7
AWD06353.1\|96139_96517_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	7.1e-58	92.1
AWD06354.1\|97272_97584_+	cytoplasmic protein	NA	NA	NA	NA
AWD06355.1\|97580_98000_+	transcriptional regulator	NA	NA	NA	NA
AWD06356.1\|98069_98483_+	hypothetical protein	A0A222YY57	Escherichia_phage	1.1e-19	46.3
AWD06357.1\|98528_99452_-\|transposase	IS5/IS1182 family transposase	Q9MCT5	Escherichia_phage	1.4e-176	99.0
AWD06358.1\|99600_99867_+	hypothetical protein	NA	NA	NA	NA
AWD06359.1\|101040_102408_-	formimidoylglutamate deiminase	NA	NA	NA	NA
AWD06360.1\|102510_103272_+	histidine utilization repressor	NA	NA	NA	NA
AWD06361.1\|103268_103826_+	hypothetical protein	NA	NA	NA	NA
AWD06362.1\|103859_105392_-	aromatic amino acid lyase	NA	NA	NA	NA
AWD06363.1\|105402_106278_-	glycine/betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
AWD06364.1\|106308_106989_-	ABC transporter permease	NA	NA	NA	NA
AWD06365.1\|106991_107636_-	ABC transporter permease	NA	NA	NA	NA
AWD06366.1\|107632_108730_-	glycine/betaine ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	7.7e-12	37.9
AWD06367.1\|109237_110914_+	urocanate hydratase	NA	NA	NA	NA
AWD06368.1\|110967_112362_+	cytosine permease	NA	NA	NA	NA
AWD06369.1\|112373_113582_+	imidazolonepropionase	NA	NA	NA	NA
AWD06370.1\|113574_114384_+	N-formylglutamate deformylase	NA	NA	NA	NA
AWD06371.1\|115124_115532_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.1e-14	40.2
AWD06372.1\|116296_117220_-\|transposase	IS5/IS1182 family transposase	Q1MVF0	Enterobacteria_phage	3.3e-173	97.7
AWD06373.1\|120494_121499_-\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
AWD06374.1\|121938_122691_-	alpha/beta hydrolase	NA	NA	NA	NA
AWD06375.1\|123294_124068_-	SDR family oxidoreductase	NA	NA	NA	NA
AWD06376.1\|124133_124835_-	DsbA family oxidoreductase	NA	NA	NA	NA
AWD06377.1\|124900_126007_-	alkene reductase	NA	NA	NA	NA
AWD06378.1\|126219_126549_+	thioredoxin	V9SJ74	Achromobacter_phage	9.7e-11	33.7
AWD06379.1\|126578_126917_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
AWD06380.1\|126921_127503_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AWD06381.1\|127621_128326_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
127569:128389	attR	NA	NA	NA	NA

DBSCAN-SWA_3

138938 : 188345

Escherichia_phage(30.77%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWD06397.1\|138938_139643_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AWD06398.1\|139633_142882_+	viral (Super1) RNA helicase	NA	NA	NA	NA
AWD06399.1\|143182_143776_-	lytic transglycosylase	NA	NA	NA	NA
AWD06400.1\|143909_144638_+	thiol:disulfide interchange protein	NA	NA	NA	NA
AWD06401.1\|144654_144960_+	hypothetical protein	NA	NA	NA	NA
AWD06402.1\|144973_145315_+	hypothetical protein	NA	NA	NA	NA
AWD06403.1\|145650_146595_+	thioredoxin	NA	NA	NA	NA
AWD06653.1\|146675_147197_+	hypothetical protein	NA	NA	NA	NA
AWD06404.1\|147193_147796_+	hypothetical protein	NA	NA	NA	NA
AWD06405.1\|148772_149450_-	hypothetical protein	NA	NA	NA	NA
AWD06654.1\|149455_149932_-	hypothetical protein	NA	NA	NA	NA
AWD06406.1\|150122_150407_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A2H4JBF4	uncultured_Caudovirales_phage	2.9e-19	54.8
AWD06407.1\|150396_150645_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
AWD06408.1\|150963_151257_-	hypothetical protein	NA	NA	NA	NA
AWD06409.1\|151310_151919_-	DUF2913 domain-containing protein	NA	NA	NA	NA
AWD06410.1\|152055_152454_-	DNA-binding protein H-NS-like protein	NA	NA	NA	NA
AWD06411.1\|152827_153184_-	hypothetical protein	A0A141HRY5	Bacillus_phage	2.1e-11	40.8
AWD06412.1\|153564_154359_-	DUF4942 domain-containing protein	NA	NA	NA	NA
AWD06413.1\|155231_156212_-\|transposase	IS5-like element ISEc68 family transposase	Q38213	Escherichia_phage	2.4e-153	80.6
AWD06414.1\|157721_158207_+	hypothetical protein	NA	NA	NA	NA
AWD06415.1\|158217_158550_-	hypothetical protein	NA	NA	NA	NA
AWD06655.1\|160472_160586_+	hypothetical protein	U5P429	Shigella_phage	3.6e-10	81.1
AWD06656.1\|160677_162249_-	GGDEF domain-containing protein	G3MA91	Bacillus_virus	4.2e-19	31.9
AWD06657.1\|163241_164165_-\|transposase	IS5/IS1182 family transposase	Q1MVF0	Enterobacteria_phage	3.3e-165	92.2
AWD06416.1\|164227_164653_-	PIN domain-containing protein	NA	NA	NA	NA
AWD06417.1\|164649_164880_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
AWD06418.1\|164911_165094_+	hypothetical protein	NA	NA	NA	NA
AWD06419.1\|165132_167709_-	EstP	NA	NA	NA	NA
AWD06420.1\|167711_169919_-	restriction endonuclease	NA	NA	NA	NA
AWD06421.1\|170649_171432_-\|transposase	transposase	A0A2L1IVB6	Escherichia_phage	2.7e-136	96.9
AWD06422.1\|171428_172451_-\|transposase	IS21-like element ISSen3 family transposase	A0A2L1IVA1	Escherichia_phage	2.1e-173	85.0
AWD06423.1\|174336_174516_+	hypothetical protein	A0A1B2IAL0	Erwinia_phage	6.8e-11	60.7
AWD06658.1\|174777_175038_+	hypothetical protein	NA	NA	NA	NA
AWD06424.1\|176130_177099_-\|transposase	IS5/IS1182 family transposase	A0A1B0VFY5	Salmonella_phage	1.0e-180	96.0
AWD06659.1\|178519_179002_+	hypothetical protein	NA	NA	NA	NA
AWD06425.1\|179277_179682_-	DUF2251 domain-containing protein	NA	NA	NA	NA
AWD06426.1\|180411_181494_+	lac repressor	C6ZCU4	Enterobacteria_phage	1.9e-188	97.8
AWD06427.1\|181615_184690_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	96.5
AWD06428.1\|184741_185986_+	MFS transporter	NA	NA	NA	NA
AWD06429.1\|186052_186223_+	galactoside O-acetyltransferase	NA	NA	NA	NA
AWD06430.1\|187268_188345_+\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

198384 : 271289

Enterobacteria_phage(12.5%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWD06439.1\|198384_199389_-\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
AWD06440.1\|199792_200803_-	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
AWD06441.1\|201040_202123_+	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	8.8e-186	96.4
AWD06442.1\|202230_205290_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	95.8
AWD06443.1\|205341_206595_+	MFS transporter	NA	NA	NA	NA
AWD06444.1\|206651_206822_+	galactoside O-acetyltransferase	NA	NA	NA	NA
AWD06445.1\|207986_208313_-	hypothetical protein	NA	NA	NA	NA
AWD06446.1\|208393_209290_-	XRE family transcriptional regulator	NA	NA	NA	NA
AWD06447.1\|209454_210531_-	dihydroorotase	NA	NA	NA	NA
AWD06448.1\|210527_211784_-	Zn-dependent hydrolase	NA	NA	NA	NA
AWD06449.1\|211820_212762_-	dihydroorotate dehydrogenase	A0A1V0SH91	Hokovirus	3.6e-18	32.6
AWD06450.1\|212754_213603_-	dihydroorotate dehydrogenase electron transfer subunit	NA	NA	NA	NA
AWD06451.1\|213967_215224_+	MFS transporter	NA	NA	NA	NA
AWD06452.1\|215436_216702_+	hypothetical protein	NA	NA	NA	NA
AWD06453.1\|217070_218051_+\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	2.3e-185	99.1
AWD06661.1\|218174_218453_+	hypothetical protein	NA	NA	NA	NA
AWD06454.1\|218549_218810_-	DUF2534 domain-containing protein	NA	NA	NA	NA
AWD06455.1\|218866_220930_-	TonB-dependent copper receptor	NA	NA	NA	NA
AWD06456.1\|221012_221432_-	DUF2946 domain-containing protein	NA	NA	NA	NA
AWD06457.1\|221792_222797_+\|transposase	IS110 family transposase	NA	NA	NA	NA
AWD06458.1\|223143_223422_-	DUF1778 domain-containing protein	NA	NA	NA	NA
AWD06459.1\|223515_223728_-	hypothetical protein	NA	NA	NA	NA
AWD06460.1\|224470_224674_+	hypothetical protein	NA	NA	NA	NA
AWD06461.1\|224703_225018_+	hypothetical protein	NA	NA	NA	NA
AWD06462.1\|225260_225713_-	hypothetical protein	NA	NA	NA	NA
AWD06463.1\|226214_227150_-\|protease	omptin family outer membrane protease Kop	NA	NA	NA	NA
AWD06464.1\|228874_229213_-	hypothetical protein	NA	NA	NA	NA
AWD06465.1\|229400_230628_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	1.7e-169	95.0
AWD06466.1\|231337_232458_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.1e-50	42.4
AWD06467.1\|232584_233484_-	RepB family plasmid replication initiator protein	A0A1B0VDL5	Salmonella_phage	6.9e-67	49.0
AWD06468.1\|234951_235206_-	hypothetical protein	NA	NA	NA	NA
AWD06469.1\|235497_235710_+	hypothetical protein	NA	NA	NA	NA
AWD06470.1\|237280_238417_+	recombinase	NA	NA	NA	NA
AWD06471.1\|238482_238800_-	hypothetical protein	NA	NA	NA	NA
AWD06472.1\|238950_239274_-	hypothetical protein	NA	NA	NA	NA
AWD06473.1\|239270_240029_-	hypothetical protein	NA	NA	NA	NA
AWD06474.1\|240025_240985_-	DNA replication protein	NA	NA	NA	NA
AWD06475.1\|241027_241435_-	hypothetical protein	NA	NA	NA	NA
AWD06476.1\|241444_241888_-	hypothetical protein	NA	NA	NA	NA
AWD06477.1\|243151_244120_+\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	2.8e-13	29.1
AWD06478.1\|245483_246221_+	hypothetical protein	NA	NA	NA	NA
AWD06479.1\|246300_246783_+	hypothetical protein	NA	NA	NA	NA
AWD06662.1\|246864_247977_+	tellurite resistance domain protein	NA	NA	NA	NA
AWD06480.1\|248026_249475_+	hypothetical protein	NA	NA	NA	NA
AWD06481.1\|249492_252561_+	virulence factor SrfB	NA	NA	NA	NA
AWD06482.1\|252560_255275_+	hypothetical protein	NA	NA	NA	NA
AWD06483.1\|255268_256288_+	hypothetical protein	NA	NA	NA	NA
AWD06484.1\|256284_258252_+	VWA domain-containing protein	NA	NA	NA	NA
AWD06485.1\|258251_258977_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.1e-17	32.8
AWD06486.1\|258966_260181_+	ABC transporter permease	NA	NA	NA	NA
AWD06487.1\|260231_261800_+	hypothetical protein	NA	NA	NA	NA
AWD06488.1\|261835_262339_+	hypothetical protein	NA	NA	NA	NA
AWD06489.1\|262398_262854_-	hypothetical protein	NA	NA	NA	NA
AWD06490.1\|262947_264540_-\|transposase	IS66-like element ISKox1 family transposase	A0A0P0ZEB3	Stx2-converting_phage	6.1e-175	61.4
AWD06491.1\|264570_264921_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBY2	Stx2-converting_phage	3.4e-38	62.9
AWD06492.1\|264917_265358_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	2.6e-19	60.3
AWD06493.1\|265554_265737_+	DUF4113 domain-containing protein	A0A1W6JNT0	Morganella_phage	9.1e-11	57.1
AWD06494.1\|267411_268383_-	ParB/RepB/Spo0J family partition protein	I3WF22	Macacine_betaherpesvirus	7.0e-150	86.9
AWD06495.1\|268382_269549_-	plasmid-partitioning protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	2.2e-222	96.9
AWD06496.1\|269504_269753_+	hypothetical protein	NA	NA	NA	NA
AWD06497.1\|269967_270249_-	hypothetical protein	NA	NA	NA	NA
AWD06498.1\|270278_271289_+	replication initiation protein	J9Q7H0	Salmonella_phage	1.1e-86	53.5

DBSCAN-SWA_5

275373 : 397668

111

Salmonella_phage(17.07%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWD06501.1\|275373_276390_+\|transposase	IS110 family transposase	NA	NA	NA	NA
AWD06502.1\|277968_279066_-	RepB family plasmid replication initiator protein	J9Q7H0	Salmonella_phage	1.5e-60	42.9
AWD06503.1\|279640_280609_-\|transposase	IS5 family transposase	A0A1B0VFY5	Salmonella_phage	1.3e-180	96.9
AWD06663.1\|281039_281948_+	HNH endonuclease	NA	NA	NA	NA
AWD06504.1\|282335_282686_-	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	4.2e-20	53.3
AWD06505.1\|282829_283261_-	silver-binding protein SilE	NA	NA	NA	NA
AWD06506.1\|283511_284987_-	Cu(+)/Ag(+) sensor histidine kinase	W8CYF6	Bacillus_phage	1.0e-27	30.1
AWD06507.1\|284979_285660_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	2.7e-31	36.0
AWD06508.1\|285849_287235_+	Cu(I)/Ag(I) efflux RND transporter outer membrane protein	NA	NA	NA	NA
AWD06509.1\|287263_287617_+	copper ABC transporter substrate-binding protein	NA	NA	NA	NA
AWD06510.1\|287730_289023_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
AWD06511.1\|289033_292180_+	CusA/CzcA family heavy metal efflux RND transporter	S5VTK5	Leptospira_phage	8.0e-62	22.6
AWD06512.1\|292266_292707_+	hypothetical protein	NA	NA	NA	NA
AWD06513.1\|292834_295276_+	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	4.9e-83	34.9
AWD06514.1\|295316_295514_+	DUF2933 domain-containing protein	NA	NA	NA	NA
AWD06515.1\|295547_296285_-	peptidase M23	A0A2H4JAF5	uncultured_Caudovirales_phage	1.2e-11	32.5
AWD06516.1\|296573_297023_-	copper resistance protein	NA	NA	NA	NA
AWD06517.1\|297257_299075_+	multicopper oxidase PcoA	NA	NA	NA	NA
AWD06518.1\|299074_299971_+	copper resistance protein B	NA	NA	NA	NA
AWD06519.1\|300010_300391_+	copper resistance system chaperone PcoC	NA	NA	NA	NA
AWD06520.1\|300395_301325_+	copper resistance protein CopD	NA	NA	NA	NA
AWD06521.1\|301379_302060_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	8.7e-30	34.4
AWD06522.1\|302056_303457_+	sensor histidine kinase	W8CYF6	Bacillus_phage	4.1e-18	26.3
AWD06523.1\|303672_304107_+	copper-binding protein	NA	NA	NA	NA
AWD06524.1\|305494_305842_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
AWD06525.1\|305838_306243_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.6e-68	97.0
AWD06526.1\|308492_308747_+	hypothetical protein	NA	NA	NA	NA
AWD06527.1\|308746_309010_+	hypothetical protein	NA	NA	NA	NA
AWD06664.1\|309239_309521_+	DNA-binding protein	NA	NA	NA	NA
AWD06528.1\|309554_310124_+	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
AWD06529.1\|310204_313000_+	heat shock survival AAA family ATPase ClpK	K4FB40	Cronobacter_phage	1.2e-128	40.9
AWD06530.1\|312999_313191_+	hypothetical protein	NA	NA	NA	NA
AWD06531.1\|313339_313678_+	GGDEF domain-containing protein	NA	NA	NA	NA
AWD06532.1\|313689_314178_+	diguanylate cyclase	NA	NA	NA	NA
AWD06533.1\|314164_315127_+\|protease	Zn-dependent protease	NA	NA	NA	NA
AWD06665.1\|315954_316269_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	1.8e-51	97.1
AWD06534.1\|316265_316613_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
AWD06535.1\|318831_319755_+\|transposase	IS5/IS1182 family transposase	Q1MVF0	Enterobacteria_phage	3.0e-166	92.8
AWD06536.1\|322592_323036_+	DUF2384 domain-containing protein	NA	NA	NA	NA
AWD06537.1\|323032_323503_+	RES domain-containing protein	NA	NA	NA	NA
AWD06538.1\|323634_324585_+\|transposase	IS5/IS1182 family transposase	Q1MVF0	Enterobacteria_phage	8.1e-167	93.2
AWD06539.1\|324586_325555_+\|transposase	IS5/IS1182 family transposase	A0A1B0VFY5	Salmonella_phage	8.5e-180	96.3
AWD06540.1\|325743_326004_-	hypothetical protein	NA	NA	NA	NA
AWD06541.1\|326353_327277_+\|transposase	IS5/IS1182 family transposase	Q1MVF0	Enterobacteria_phage	6.9e-171	96.4
AWD06542.1\|327615_328827_-	creatininase	NA	NA	NA	NA
AWD06543.1\|328913_329867_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	1.7e-10	24.0
AWD06544.1\|330023_330872_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AWD06545.1\|330895_331567_+	amino acid ABC transporter permease	NA	NA	NA	NA
AWD06546.1\|331563_332226_+	amino acid ABC transporter permease	NA	NA	NA	NA
AWD06547.1\|332230_333049_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.8e-29	38.3
AWD06548.1\|333045_334011_+	EamA/RhaT family transporter	NA	NA	NA	NA
AWD06549.1\|334079_335060_+\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	6.8e-185	98.8
AWD06550.1\|335605_336529_-\|transposase	IS5/IS1182 family transposase	Q1MVF0	Enterobacteria_phage	3.3e-173	97.7
AWD06551.1\|336935_337724_-	hypothetical protein	NA	NA	NA	NA
AWD06552.1\|337723_338188_-	hypothetical protein	NA	NA	NA	NA
AWD06553.1\|339126_339540_+	hypothetical protein	NA	NA	NA	NA
AWD06554.1\|339732_340257_+	hypothetical protein	NA	NA	NA	NA
AWD06555.1\|340458_341382_+\|transposase	IS5/IS1182 family transposase	Q1MVF0	Enterobacteria_phage	5.6e-165	91.9
AWD06556.1\|341597_343463_+	DUF262 domain-containing protein	NA	NA	NA	NA
AWD06557.1\|343666_345223_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.6e-106	43.1
AWD06558.1\|345219_346545_+	restriction endonuclease subunit S	NA	NA	NA	NA
AWD06559.1\|346666_349783_+	DEAD/DEAH box helicase	A0A220A398	Liberibacter_phage	4.6e-25	23.8
AWD06560.1\|349844_350060_-	DNA modification methylase	J9Q747	Salmonella_phage	1.1e-15	71.7
AWD06561.1\|350626_351631_-\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
AWD06562.1\|351715_354694_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	4.7e-306	54.2
AWD06563.1\|354853_355438_+	recombinase family protein	A0A219YA40	Aeromonas_phage	2.6e-22	36.1
AWD06564.1\|355622_356180_+	OsmC family peroxiredoxin	NA	NA	NA	NA
AWD06565.1\|356326_357031_+\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AWD06566.1\|358030_361975_-	conjugal transfer protein TraG	NA	NA	NA	NA
AWD06666.1\|361976_363332_-	conjugal transfer protein	NA	NA	NA	NA
AWD06567.1\|363375_364413_-	conjugal transfer protein TraF	NA	NA	NA	NA
AWD06568.1\|364772_365315_-	hypothetical protein	NA	NA	NA	NA
AWD06569.1\|365331_365856_-	hypothetical protein	NA	NA	NA	NA
AWD06570.1\|366049_366538_-	hypothetical protein	NA	NA	NA	NA
AWD06571.1\|367414_367879_+	hypothetical protein	NA	NA	NA	NA
AWD06572.1\|367878_368688_+	hypothetical protein	NA	NA	NA	NA
AWD06573.1\|368702_371663_+	conjugal transfer protein TraI	NA	NA	NA	NA
AWD06574.1\|371652_373779_+	conjugal transfer protein TraD	NA	NA	NA	NA
AWD06575.1\|373781_374879_+	hypothetical protein	NA	NA	NA	NA
AWD06576.1\|374891_375566_+	DUF4400 domain-containing protein	NA	NA	NA	NA
AWD06577.1\|375574_376711_+	S49 family peptidase	B8QTU8	Erwinia_phage	4.4e-10	32.4
AWD06578.1\|376717_377491_+	NERD domain-containing protein	A0A2R2ZH57	Clostridioides_phage	6.0e-11	32.1
AWD06579.1\|377542_377899_-	hypothetical protein	NA	NA	NA	NA
AWD06580.1\|378251_378437_-	hypothetical protein	NA	NA	NA	NA
AWD06581.1\|378526_378874_-	hypothetical protein	NA	NA	NA	NA
AWD06582.1\|378946_379201_-	hypothetical protein	NA	NA	NA	NA
AWD06583.1\|379295_379511_-	hypothetical protein	NA	NA	NA	NA
AWD06584.1\|381098_382022_-\|transposase	IS5-like element IS903B family transposase	Q9MCT5	Escherichia_phage	1.1e-176	99.3
AWD06585.1\|382121_382646_-	hypothetical protein	A0A0M4R5D1	Salmonella_phage	1.9e-08	33.3
AWD06586.1\|383038_383413_-	hypothetical protein	NA	NA	NA	NA
AWD06587.1\|383424_383760_-	hypothetical protein	NA	NA	NA	NA
AWD06588.1\|383770_384082_-	plasmid maintenance system killer family protein	NA	NA	NA	NA
AWD06589.1\|384352_384625_+	2Fe-2S ferredoxin-like protein	G9IAA2	Pseudomonas_phage	1.6e-11	50.0
AWD06590.1\|384946_385561_+	Eac protein	A0A220NQT7	Salmonella_phage	1.9e-52	50.0
AWD06591.1\|385625_386063_+	hypothetical protein	NA	NA	NA	NA
AWD06592.1\|386340_386649_+	hypothetical protein	NA	NA	NA	NA
AWD06593.1\|386813_387479_+	hypothetical protein	NA	NA	NA	NA
AWD06594.1\|387523_387823_+	hypothetical protein	NA	NA	NA	NA
AWD06595.1\|388264_388582_-	DUF3846 domain-containing protein	A0A2H4P7A4	Pseudomonas_phage	4.3e-08	41.9
AWD06596.1\|388610_388859_-	hypothetical protein	NA	NA	NA	NA
AWD06597.1\|389432_390635_+	restriction endonuclease	E5E3X4	Burkholderia_phage	3.2e-35	39.3
AWD06598.1\|390726_392142_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	5.3e-106	50.9
AWD06599.1\|392275_392710_-	hypothetical protein	NA	NA	NA	NA
AWD06667.1\|392742_393003_-	hypothetical protein	A0A0M3LSW2	Mannheimia_phage	2.6e-11	40.8
AWD06600.1\|393011_393215_-	hypothetical protein	NA	NA	NA	NA
AWD06601.1\|393256_393700_-	hypothetical protein	NA	NA	NA	NA
AWD06602.1\|393969_394680_+	RES domain-containing protein	NA	NA	NA	NA
AWD06603.1\|394717_395359_-	DNA-binding protein	NA	NA	NA	NA
AWD06604.1\|395488_395848_+	hypothetical protein	NA	NA	NA	NA
AWD06605.1\|396204_396411_+	hypothetical protein	NA	NA	NA	NA
AWD06606.1\|396744_397668_+\|transposase	IS5-like element IS903B family transposase	Q9MCT5	Escherichia_phage	1.1e-176	99.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP028951

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP028952

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection