CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
CP026497	Klebsiella pneumoniae strain 616 plasmid pKp616_2, complete sequence	0 crisprs	NA	1
CP026496	Klebsiella pneumoniae strain 616 plasmid pKp616_1, complete sequence	0 crisprs	NA	1
CP026495	Klebsiella pneumoniae strain 616 chromosome, complete genome	1 crisprs	csa3,cas3,DEDDh,DinG,RT,WYL	4

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

8565 : 18362

Escherichia_phage(37.5%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWG15290.1\|8565_9000_+	peptidase	A0A1W6JNS2	Morganella_phage	1.9e-30	56.1
AWG15291.1\|9982_11473_-	PAS domain S-box protein	A0A1B0V854	Salmonella_phage	1.7e-78	98.7
AWG15292.1\|11552_12257_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AWG15293.1\|12338_13199_-	class A extended-spectrum beta-lactamase SHV-2a	A0A077SL40	Escherichia_phage	7.6e-156	99.7
AWG15294.1\|13162_13345_-	hypothetical protein	NA	NA	NA	NA
AWG15295.1\|13335_14040_+\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AWG15296.1\|13985_14234_-	hypothetical protein	NA	NA	NA	NA
AWG15297.1\|14374_14836_+	hypothetical protein	NA	NA	NA	NA
AWG15298.1\|14832_15081_+	XRE family transcriptional regulator	A0A248SLB9	Klebsiella_phage	1.6e-10	53.0
AWG15299.1\|15073_15661_+	restriction endonuclease	NA	NA	NA	NA
AWG15300.1\|15657_16143_+	hypothetical protein	NA	NA	NA	NA
AWG15346.1\|16184_16388_+	hypothetical protein	NA	NA	NA	NA
AWG15301.1\|16406_17147_+	resolvase	I3WFA4	Macacine_betaherpesvirus	9.5e-22	51.6
AWG15347.1\|17387_18362_+	recombinase	A0A0A7NPX4	Enterobacteria_phage	6.1e-85	52.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP026496

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 39249

Escherichia_phage(33.33%)

integrase,transposase

attL 27214:27273|attR 33444:34369

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWG15212.1\|0_720_+	RepB family plasmid replication initiator protein	I3WF20	Macacine_betaherpesvirus	8.6e-20	28.9
AWG15213.1\|1662_2325_+	hypothetical protein	NA	NA	NA	NA
AWG15214.1\|2676_3246_-	recombinase family protein	E5FFF9	Burkholderia_phage	5.2e-36	43.2
AWG15215.1\|3595_4300_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AWG15216.1\|4276_4600_+	hypothetical protein	A0A1B0VDR3	Salmonella_phage	2.2e-36	100.0
AWG15217.1\|4855_5731_+	class A extended-spectrum beta-lactamase CTX-M-15	A0A1B0VBP7	Salmonella_phage	1.1e-125	82.4
AWG15218.1\|5978_6683_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AWG15219.1\|7654_8188_-	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	5.8e-21	33.9
AWG15220.1\|8187_9183_-	conjugal transfer protein TraG	NA	NA	NA	NA
AWG15221.1\|9224_10385_-	conjugal transfer protein TraF	NA	NA	NA	NA
AWG15222.1\|10384_11206_-	conjugal transfer protein TraO	NA	NA	NA	NA
AWG15223.1\|11279_11978_-	type IV secretion system protein VirB8	NA	NA	NA	NA
AWG15224.1\|11967_12114_-	conjugal transfer protein TraN	NA	NA	NA	NA
AWG15225.1\|12196_13237_-	conjugal transfer protein TraD	NA	NA	NA	NA
AWG15226.1\|13252_13480_-	entry exclusion protein	NA	NA	NA	NA
AWG15227.1\|13487_14201_-	type IV secretion system protein	NA	NA	NA	NA
AWG15228.1\|14218_16819_-	VirB4 family type IV secretion/conjugal transfer ATPase	NA	NA	NA	NA
AWG15229.1\|16818_17136_-	type IV secretion system protein VirB3	NA	NA	NA	NA
AWG15230.1\|17185_17479_-	conjugal transfer protein TraM	NA	NA	NA	NA
AWG15278.1\|17488_17770_-	transcriptional regulator	NA	NA	NA	NA
AWG15231.1\|17778_18513_-	traL protein	NA	NA	NA	NA
AWG15279.1\|18576_18927_+	KorB	NA	NA	NA	NA
AWG15232.1\|18942_19287_+	hypothetical protein	NA	NA	NA	NA
AWG15233.1\|19283_19598_+	IncN plasmid KikA protein	NA	NA	NA	NA
AWG15234.1\|19633_19945_+	hypothetical protein	NA	NA	NA	NA
AWG15280.1\|20000_20642_+	restriction endonuclease	NA	NA	NA	NA
AWG15235.1\|20646_20853_+	hypothetical protein	NA	NA	NA	NA
AWG15236.1\|21234_22668_+	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	7.0e-106	50.6
AWG15237.1\|22701_23910_-	restriction endonuclease	E5E3X4	Burkholderia_phage	1.2e-34	42.5
AWG15238.1\|23922_24135_-	resolvase	NA	NA	NA	NA
AWG15239.1\|24176_24941_-\|transposase	IS6 family transposase IS6100	A0A077SL39	Escherichia_phage	4.3e-86	65.7
AWG15240.1\|25083_25350_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
AWG15241.1\|25570_26053_-	trimethoprim-resistant dihydrofolate reductase DfrA14	G3MBI7	Bacillus_virus	6.6e-16	28.9
AWG15242.1\|26199_27213_+\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
AWG15243.1\|27151_27343_+	hypothetical protein	NA	NA	NA	NA
27214:27273	attL	NA	NA	NA	NA
AWG15244.1\|27379_28084_+\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AWG15245.1\|28931_30140_-	restriction endonuclease	E5E3X4	Burkholderia_phage	1.2e-34	42.5
AWG15246.1\|30152_30365_-	resolvase	NA	NA	NA	NA
AWG15247.1\|30406_31171_-\|transposase	IS6 family transposase IS6100	A0A077SL39	Escherichia_phage	4.3e-86	65.7
AWG15248.1\|31313_31580_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
AWG15249.1\|31800_32283_-	trimethoprim-resistant dihydrofolate reductase DfrA14	G3MBI7	Bacillus_virus	6.6e-16	28.9
AWG15250.1\|32429_33443_+\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
AWG15251.1\|33381_33573_+	hypothetical protein	NA	NA	NA	NA
AWG15252.1\|33609_34314_+\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AWG15253.1\|34624_35164_+\|transposase	IS91 family transposase	NA	NA	NA	NA
33444:34369	attR	NA	NA	NA	NA
AWG15254.1\|35135_35972_-	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
AWG15255.1\|35971_36775_-	aminoglycoside O-phosphotransferase APH(3'')-Ib	NA	NA	NA	NA
AWG15256.1\|36835_37651_-	sulfonamide-resistant dihydropteroate synthase Sul2	A0A0B5J4J5	Pandoravirus	5.9e-09	27.6
AWG15257.1\|37980_38157_+	DUF4102 domain-containing protein	T1S9J3	Salmonella_phage	1.0e-06	68.6
AWG15258.1\|38544_39249_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP026495

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CRISPR-Cas detection and classification

Crispr_ID: CP026495_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026495_1

4363653-4363747

Orphan

Consensus_repeat	Method
ACTATGGTTTTTATGGTTTTTATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026495_1

>merge|CP026495|1|4363653-4363747|CRISPRCasFinder
TTAATGGTCACTATGGTTTTTATGGTTTTTATTCGCTGAACTGCCCGGGAGTGATATATCTCTGATTTATGACTGTGGTTTTTATGGTTTTTATT

>CP026495|1|1|4363653-4363747|CRISPRCasFinder
TTAATGGTCACTATGGTTTTTATG	GTTTTTATTCGCTGAACTGCCCGGGAGTGATATATCTCTGATTTATG
ACTGTGGTTTTTATGGTTTTTATT

Protein	Signature genes	Signature genes Name	Protein_function
CP026495.1\|AWG14206.1\|4369708_4370995_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
CP026495.1\|AWG14207.1\|4371000_4371990_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
CP026495.1\|AWG14193.1\|4349868_4350714_-\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
CP026495.1\|AWG14208.1\|4371986_4372808_+\|ribosomal-RNA-small-subunit-methyltransferase-A	unknown	unknown	gnl\|CDD\|234708
CP026495.1\|AWG15173.1\|4361982_4362171_+\|hypothetical-protein	unknown	unknown	unknown
CP026495.1\|AWG14198.1\|4357827_4360734_+\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
CP026495.1\|AWG14194.1\|4351051_4352761_+\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
CP026495.1\|AWG14211.1\|4373993_4374197_-\|hypothetical-protein	unknown	unknown	unknown
CP026495.1\|AWG14202.1\|4363888_4365514_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
CP026495.1\|AWG14203.1\|4365503_4366202_+\|response-regulator	unknown	unknown	gnl\|CDD\|226931
CP026495.1\|AWG14205.1\|4367305_4369654_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
CP026495.1\|AWG14195.1\|4352771_4354274_+\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
CP026495.1\|AWG14204.1\|4366234_4367062_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
CP026495.1\|AWG14197.1\|4355282_4357640_+\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595
CP026495.1\|AWG14196.1\|4354411_4355107_+\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
CP026495.1\|AWG14199.1\|4360746_4361406_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
CP026495.1\|AWG14209.1\|4372810_4373188_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
CP026495.1\|AWG14200.1\|4361480_4362020_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	unknown	unknown	gnl\|CDD\|163145
CP026495.1\|AWG14210.1\|4373192_4374041_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	unknown	unknown	gnl\|CDD\|273208
CP026495.1\|AWG14201.1\|4362199_4363564_-\|malate-permease	unknown	unknown	gnl\|CDD\|377030

Protein	Function_ID	Function_description	E-value
CP026495.1\|AWG14206.1\|4369708_4370995_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
CP026495.1\|AWG14207.1\|4371000_4371990_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
CP026495.1\|AWG14193.1\|4349868_4350714_-\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
CP026495.1\|AWG14208.1\|4371986_4372808_+\|ribosomal-RNA-small-subunit-methyltransferase-A	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	3.65731e-147
CP026495.1\|AWG14198.1\|4357827_4360734_+\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
CP026495.1\|AWG14194.1\|4351051_4352761_+\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
CP026495.1\|AWG14200.1\|4361480_4362020_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	gnl\|CDD\|163145	TIGR03124, citrate_citX, holo-ACP synthase CitX. Members of this protein family are the CitX protein, or CitX domain of the CitXG bifunctional protein, of the citrate lyase system. CitX transfers the prosthetic group 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA to the citrate lyase gamma chain, an acyl carrier protein. This enzyme may be designated holo-ACP synthase, holo-citrate lyase synthase, or apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. In a few genera, including Haemophilus, this protein occurs as a fusion protein with CitG (2.7.8.25), an enzyme involved in prosthetic group biosynthesis. This CitX family is easily separated from the holo-ACP synthases of other enzyme systems. [Energy metabolism, Fermentation, Protein fate, Protein modification and repair].	5.54697e-86
CP026495.1\|AWG14202.1\|4363888_4365514_+\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	7.63459e-173
CP026495.1\|AWG14205.1\|4367305_4369654_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
CP026495.1\|AWG14195.1\|4352771_4354274_+\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
CP026495.1\|AWG14204.1\|4366234_4367062_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	2.63694e-164
CP026495.1\|AWG14197.1\|4355282_4357640_+\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
CP026495.1\|AWG14203.1\|4365503_4366202_+\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	1.65624e-65
CP026495.1\|AWG14199.1\|4360746_4361406_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	2.4454e-161
CP026495.1\|AWG14209.1\|4372810_4373188_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	7.84855e-74
CP026495.1\|AWG14196.1\|4354411_4355107_+\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	0
CP026495.1\|AWG14210.1\|4373192_4374041_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	gnl\|CDD\|273208	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical). Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a regulatory metabolite of stress conditions. It is hydrolyzed to two ADP by this enzyme. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase. [Cellular processes, Adaptations to atypical conditions].	0
CP026495.1\|AWG14201.1\|4362199_4363564_-\|malate-permease	gnl\|CDD\|377030	pfam03390, 2HCT, 2-hydroxycarboxylate transporter family. The 2-hydroxycarboxylate transporter family is a family of secondary transporters found exclusively in the bacterial kingdom. They function in the metabolism of the di- and tricarboxylates malate and citrate, mostly in fermentative pathways involving decarboxylation of malate or oxaloacetate.	4.87969e-169

>CP026495.1|AWG14201.1|4362199_4363564_-|malate-permease
MSTTDNAFSATLEPIDTPKTTLKQRWWHIMDNWKVGIVPLPLFLLAGGLIALDCLGGKLPSDIVVMVATLAFFGFACGEFGKRLPVLGKLGAAAICATFIPSALVHYGLLPDVVIESTTKFYKSTNILYLYICCIIVGSIMSMNRTTLIQGFLKIFFPMLCGEVVGMLVGIGVGTLLGMEPFQVFFFIVLPIMAGGVGEGAIPLSMGYAALMHMEQGVALGRVLPMVMLGSLTAIVISGCLNQLGKRFPHLTGEGQLMPNRSHETRSLSESEGVSGKTDVGTLASGALLAVLLYMMGMLGHKLIGLPAPVGMLFLAVLLKLANVVSPRLQEGSQMVYKFFRTAVTYPILFAVGVAITPWQELVNAFTLTNLLVIVSTVSALVATGFLVGKKIGMHPIDVAIVSCCQSGQGGTGDVAILTAGNRMSLMPFAQIATRIGGAINVSLGLLFLSHYLA
>CP026495.1|AWG15173.1|4361982_4362171_+|hypothetical-protein
MLTPAWAGVSTDINSSPTYDKYDSAWTVMMMVAIADRALIVTLNAEHLGYRTQIFSAFCSGK
>CP026495.1|AWG14200.1|4361480_4362020_-|citrate-lyase-holo-[acyl-carrier-protein]-synthase
MSVDTPAQAGVSIDALLAAKEQRAARQADWLAHYQQPVISLTLVTPGAVKDSIRYRNMMGVALQACDQLLWKHRWQTLDRQVLWLPTGPEALWCVAHPASEIKAMCSTLEQSHPLGRLWDIDVICPQNGLVGRQSLGESQRRCLLCDEPAHACARSRRHDTDLVVARVEQMIDAWFARD
>CP026495.1|AWG14199.1|4360746_4361406_+|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MAMENYNPPQDPWLVILYQDEHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDFPQAESVHRLDMATSGVIVVALNKAAERELKRQFREREPKKQYVARVWGHPQPAEGLVDLPLICDWPNRPKQKVCYETGKAAQTEYEVLEYAEDNTARVRLKPITGRSHQLRVHMLALGHPILGDRFYATPEALAMAPRLLLHAETLTITHPAYGNAMTFRAPIDF
>CP026495.1|AWG14198.1|4357827_4360734_+|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVALDARMVTLLFPAIGENRLYSRNDSPITRVMFNPGDTITSHEGWQLHVDKVNEENGLLSYTGTRLDTQEANVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPWSGLRGQRTSLIPHQLHIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIVVPETLQHQWLVEMLRRFNLRFSLFDDERYAEAQHDAYNPFETEQLVICSLDFVRRSKQRLEHLCDAEWDLMVVDEAHHLVWSEEAPSREYQAIEQLAERVPGILLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQQNYRPVADAVALLLAGNKLSDSELNTLGDLIGEQDIEPLLQAANSDREDAQAARQELISMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIRLPLPTQYQTAIKVSGIMGARKTAEERARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKATTALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTVYDSVHDELINYLAAPESTDGFDDLIKSCRQQHDALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTSLIAFSMNLFDIVGINQDDRGENLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLLELIYVVEAQAPKQLQLNRFLPATPVRMLLDKNGNNLAAQVEFESFNRQLSAVNRHTGSKLVNAVQQDVHAILQQGEAQIAKAAQGLIDAARNEADEKLTAELSRLEALKAVNPNIRDDELAAIESNRQQVMDALAQAGWRLDALRLIVVTHQ
>CP026495.1|AWG14197.1|4355282_4357640_+|DNA-polymerase-II
MTQPRAGFLLTRHWRDTPQGTELSFWLATDDGPLQVTLPPQESVAFIPEAQRAQAERLLQGEKGLRFAPLALKDFHRQPIVGLYCRAHRQLMRLEKMLRDSGVTVYEGDIRPPERYLMERFITAPVWVEGETRGSQLVNARMKPNPDYRPPLKWVSLDIETSRHGELYCIGLEGCGQRVVYMLGPEPETPPDVDFELVFIASRPLLLEKLNAWFAEHDPDVLIGWNVVQFDLRVLQKHAERYRIPLRLGRGNSELEWREHGFKNGVFFAQANGRLIIDGIDALKSAFWNFSSFSLEAVARELLGEGKAIDNPWDRMDEIERRFHEDKPALAIYNLQDCELVTRIFHKTEIMPFLLERATVNGLPADRHGGSVAAFSHLYFPRMHRLGYVAPNLGDVPPQASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGLAQPDDQHSIEGFLGARFSRDKHCLPGIVSQIWHGRDEAKRQHNKPLSQALKIIMNAFYGVLGTSACRFFDPRLASSITMRGHAIMRQTKALIEAKGYDVIYGDTDSTFVWLKRPHSEAQAAEIGRELVSDVNAWWAQEFSKSQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGMIQEGDAQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNQPYQDYVRETIARLMNGELDEQLVYRKRLRRPLAEYQRNVPPHVRAARLADEHNLKLGRAQQYQQRGTIKYVWTTSGPEPVDYQQSPLDYDHYLTKQLQPVAEGILPFVNDDFATIVTGQLGLF
>CP026495.1|AWG14196.1|4354411_4355107_+|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDREKGVFVIKPSGVDYRVMTADDMVVVSLESGEVVEGNKKPSSDTPTHRLLYQAFPTLGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGPVPCTRLMTDAEINGDYEWETGNVIVETFRQQGIDPAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEIAYMGIFCRQLAPQLPAMQQTLLDKHYLRKHGAKAYYGQ
>CP026495.1|AWG14195.1|4352771_4354274_+|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPEALRQVTKHAEHVVNSLNAEAKLPCKLVLKPLGTTPDEITHICRDANYDDKCAGLVVWLHTFSPAKMWINGLTILNKPLLQFHTQYNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHSVVTGHWQDKEAHQRIGGWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDISALVDEYESSYRLTPAAQVHGEKRQNVLDAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFDNGNDLVLGSHMLEVCPTIATAEKPILDVQPLGIGGKADPARLIFNTQTGPAIVASLIDLGDRFRLLVNTIETVPTPHDLPKLPVANALWKAQPDLRTASEAWIIAGGAHHTVFSHALNLDDMRQFAELHDIELTVIDNDTRLPSFKDALRWNEVYYGSKR
>CP026495.1|AWG14194.1|4351051_4352761_+|ribulokinase
MAIAIGLDFGSDSVRALAVECASGAELATSVEWYPRWREGQYCDGANNRFRHHPRDYIESMEAALKSVLASLSAEQRADVVGIGVDSTGSTPAPVDAEGNVLALREEFADNPNAMFVLWKDHTAVEEAEAITRLCHQPGKEDYSRYIGGIYSSEWFWAKILHVTREDSAVAHAAASWVELCDWVPALLSGTTRPQDLRRGRCSAGHKSLWHESWGGLPPASFFDELDPIINQHLAWPLFTDTWTADVPVGTLSAEWAQRLGLSQSVAISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKESVGERTVKGICGQVDGSVVPHFIGMEAGQSAFGDIYAWFGRILGWPLEQLAQQQPALREQIKASQKQLLPALTEAWANNPSLEHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLIAATAFGARAIMECFTEQGIPVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAGVYDDIPAAQQRMASQVETTLQPRPAQAQRFEQLYQRYQQWSVSAEQHYLPSAAKAEKAPQSQAALTH
>CP026495.1|AWG14193.1|4349868_4350714_-|arabinose-operon-transcriptional-regulator-AraC
MAETQNDPLLPGYSFNAHLVTGLTPIEAQGYLDFFIDRPLGMKGYILNLTIRGEGVINNHGEQFVCRPGDMLLFPPGEIHHYGRHPDASEWYHQWVYFRPRAYWHEWLNWPTIFAQTGFFRPDEQWQARFGELFGQIVDAGQGAGRYSELLAINLLEQLLLRRMEAINESLHPPLDNRVRDACQYISDHLADSHFDIASVAQHVCLSPSRLSHLFRQQLGVSVLGWREDQRISQAKLLLSTTRMPIATVGRNVGFEDQLYFSRVFKKCTGASPSEFRAGCE
>CP026495.1|AWG14202.1|4363888_4365514_+|sensor-histidine-kinase
MKLSFQYKLFISLVAFFSVLFIALGIYYYFDASRQLYQEMSARAKIQAEEIALMPNLRQQVSRHDPQAIQAFMQQIAAHSDASFIVIGDRQGVHLFHSVHPEWVGTRLVGGDNQAVLEGKSITTIRKGGLGVSLRSKTPIVDDAGRVIGIVSVGYLTSYLDSITLTKVINIFIAAVLLLIALFIFSWYFTRSIKKQIFSLEPREIGLLVRQQKAMMESIFEGVIVIDRQRRIEVINHAARSLLGLSQPARQLRGQSIDSVISPQPFFASGDMLERDTHDELCRFNQLTVLASRVRIMLENTLQGWVITFRDRNEINALTAQLSQVKRYVDNLRIMRHEQLNRMTTLSGLLHMGHYDEAIRYIQAQSEHAQELLDFISSHFHSPTLCGLLLGKATRAREKGVALSFDPACRIDRPLPSLMESELISIIGNLLDNAIEATQRAELPHEPVEVLIQLNARELIIEVADRGVGIRPDIRERIFERGVTTKTRGDHGIGLYLIEHYVTQAGGTIEVADNAPRGTIFTLFIPADAHACPQPEVHDAS
>CP026495.1|AWG14203.1|4365503_4366202_+|response-regulator
MHHDLVDVLIIEDESELARLHAELVQKHPRLRLAGMAASLAQARQLLHATPPQLVLLDNYLPDGKGVTLMTDPALATSQCSVIFITAASDMETCSQAIRNGAFDYILKPVSWKRLSQSLERFIQFYDQQREWKIVDQQNVDSLYQLQAKNYRVDSGSKGIEEKTLALVQGLFSGREAHCFSVDEVVSAAGLSKTTARRYLEHGVETGFLEVEMLYGKIGHPRRLYRRAKVKS
>CP026495.1|AWG14204.1|4366234_4367062_-|co-chaperone-DjlA
MQYLGKVIGVAVALLMGGGFWGVVLGFLVGHMFDRARSRRLNLFANQQERQSLFFSTTFEVMGHLTKSKGRVTEADIHVANVLMDRMNLHGASRTAAQQAFRDGKADNYPLREKMRQLRSVCFGRFDLIRMFLEIQLQAAFADGELHPNEREVLFVIADELGISRAQFDQFLRMMQGGAQFGGGSQQRSYGQHGGNAGWQQAQRGPTLEDACNVLGVKPTDDAATVKRAYRKLMNEHHPDKLVAKGLPPEMMEMAKQKAQEIQKAWELIKEQRGF
>CP026495.1|AWG14205.1|4367305_4369654_+|LPS-assembly-protein-LptD
MKKRIPSLLATMIASALYSQQGLAADLATQCMLGVPSYDRPLVEGRPGDLPVTINADHAKGNYPDNAVFTGNVDINQGNSRLRADEVQLHQQQAAGQAQPVRTVDALGNVHYDDNQVILKGPKAWSNLNTKDTNVWQGDYQMVGRQGRGTADLMKQRGENRYTILENGSFTSCLPGSDTWSVVGSEVIHDREEQVAEIWNARFKLGSVPIFYSPYLQLPVGDKRRSGFLIPNAKYSTKNGVEFSLPYYWNIAPNFDATITPHYMNKRGGVMWENEFRYLTQLGSGLTEFDYLPSDKVYEDDHSSDSNSRRWLFYWNHSGVIDQVWRLNADYTKVSDPDYFNDFSSKYGSSTDGYATQKFSAGYVNQNFDATVSTKQFQVFDRESSNSYSAEPQLDVNYYQNDVGPFDTHLYGQVAHFVNSNNNMPEATRVHFEPTINLPLSNGWGSLNTEAKLLATHYQQSNLDKYNAANGTDYKESVSRVMPQFKVDGKMVFERDLQEGFTQTLEPRVQYLYVPYRDQSEIGNYDSTLLQSDYTGLFRDRTYSGLDRIASANQVTTGLTSRVYDAAAVERFNISVGQIYYFTESRTGDDNINWENNDTTGSLVWAGDTYWRIADEWGLRGGIQYDTRLDNVATGNGTIEYRRDENRLVQLNYRYASPEYIQATLPSYSTAAQYKQGISQVGMTASWPIVDRWSVVGAYYYDTNTRKAANQMLGVQYNSCCYAIRLGYERKVNGWNSNDNGGESKYDNTFGINIELRGLSSNYGLGTQQMLRSNILPYQSSL
>CP026495.1|AWG14206.1|4369708_4370995_+|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAGQAGQQLPDDATLRHQILERLIMDQIVLQMGQKMGVKISDDQLDQAIANIAKQNNMTLDQMRSRLAYEGINYNTYRNQIRKEMLISEVRNNEVRRRITVLPQEVEALAKQIGDQNDASTELNLSHILIPLPENPTSDEVAAAQEQANSIVEQARNGANFGKLAITYSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGGTQNISVTEVHARHILLKPSPIMNDAQAQAKLEQIAAEIKSGKITFAQAAKTYSEDPGSANQGGDLGWATPDIFDPAFRDALMRLNKGQTSGPVHSSFGWHLIELLDSRQVDRTDAAQKDRAYRMLMNRKFSEEAATWMQEQRASAYVKILSN
>CP026495.1|AWG14207.1|4371000_4371990_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MPETRKVVITPGEPAGIGPDLVVQLAQRDWPVELVICADGALLTDRAKRLGLPLSLLPYDPAQPPVPQRAGTLTLLNVALNVPAEPGVLNVQNGAYVVETLARACDGCLSGEFAALVTGPVHKGNINDAGIAFTGHTEFFEERAKASKVVMMLATEELRVALVTTHLPLKAISEAITPELLREIITILDHDLRTKFGIAQPHVLVCGLNPHAGEGGHMGTEEIDTIIPVLEEMRAKGMNLSGPLPADTLFQPKYLDHADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGQGKADVGSFITALNLAIKMIVNTQ
>CP026495.1|AWG14208.1|4371986_4372808_+|ribosomal-RNA-small-subunit-methyltransferase-A
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHSTMPYPVKEIRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTELGIDPAMRAENISVAQYCLMANWLSDNLPTKES
>CP026495.1|AWG14209.1|4372810_4373188_+|Co2+/Mg2+-efflux-protein-ApaG
MIHSPRVCVQVQSVYIESQSSPEEERYVFAYTVTIRNLGRSQVQLLGRYWLITNGHGRETEVQGEGVVGEQPHIPAGGEYQYTSGAVIETPLGTMQGHYEMIDIDGAPFRIEIPVFRLAVPTLIH
>CP026495.1|AWG14210.1|4373192_4374041_+|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)
MSTYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLKPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMPNHWSNELSGLARLRFISNAFTRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGIYALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS
>CP026495.1|AWG14211.1|4373993_4374197_-|hypothetical-protein
MFPVAGFVFFLKRSPGRQTAHKRRSGKALAATRQNDAAGSPDKAQRAAIREESGRDGFAFVEAFLPV

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1436097 : 1533593

Escherichia_phage(18.75%)

plate,head,portal,tail,capsid,holin,tRNA,protease,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWG11579.1\|1436097_1437447_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
AWG11580.1\|1437443_1438133_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
AWG11581.1\|1438132_1439809_+	OmpA family protein	NA	NA	NA	NA
AWG11582.1\|1439811_1440303_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
AWG11583.1\|1440723_1443081_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
AWG15033.1\|1443090_1443633_+	hypothetical protein	NA	NA	NA	NA
AWG11584.1\|1443706_1444177_+	DUF3828 domain-containing protein	NA	NA	NA	NA
AWG15034.1\|1444519_1446922_+	hypothetical protein	NA	NA	NA	NA
AWG11585.1\|1446918_1447362_+	hypothetical protein	NA	NA	NA	NA
AWG11586.1\|1447519_1447903_+	DUF4087 domain-containing protein	NA	NA	NA	NA
AWG11587.1\|1448004_1448373_+	hypothetical protein	NA	NA	NA	NA
AWG11588.1\|1449019_1449319_+	DUF1311 domain-containing protein	NA	NA	NA	NA
AWG15035.1\|1449381_1449645_+	PAAR domain-containing protein	R9U4D0	Rhizobium_phage	1.2e-06	50.0
AWG11589.1\|1449647_1450856_+	hypothetical protein	NA	NA	NA	NA
AWG11590.1\|1450848_1454220_+	type VI secretion protein VasK	NA	NA	NA	NA
AWG11591.1\|1454712_1456320_+	type VI secretion system protein TssA	NA	NA	NA	NA
AWG11592.1\|1456353_1458123_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
AWG11593.1\|1458086_1459169_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
AWG11594.1\|1459204_1459729_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
AWG11595.1\|1459733_1462055_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	2.7e-14	29.0
AWG11596.1\|1462051_1462555_+	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	1.5e-18	40.0
AWG11597.1\|1462548_1462893_+	hypothetical protein	NA	NA	NA	NA
AWG15036.1\|1462925_1463663_+	hypothetical protein	NA	NA	NA	NA
AWG15037.1\|1463905_1464388_+	hypothetical protein	NA	NA	NA	NA
AWG11598.1\|1466271_1467156_+	glycine zipper family protein	NA	NA	NA	NA
AWG11599.1\|1467145_1467703_+	hypothetical protein	NA	NA	NA	NA
AWG15038.1\|1468210_1468609_+	hypothetical protein	NA	NA	NA	NA
AWG11600.1\|1469473_1469656_+	hypothetical protein	NA	NA	NA	NA
AWG11601.1\|1469843_1470377_+	hypothetical protein	NA	NA	NA	NA
AWG11602.1\|1471524_1472694_+	DUF4102 domain-containing protein	A0A2R2Z2Y0	Escherichia_phage	1.9e-202	86.1
AWG11603.1\|1473068_1473641_+	hypothetical protein	NA	NA	NA	NA
AWG11604.1\|1473742_1473943_-	hypothetical protein	G3CFG7	Escherichia_phage	1.8e-12	60.0
AWG11605.1\|1474750_1475266_-	hypothetical protein	A0A0P0ZBM8	Stx2-converting_phage	2.9e-70	76.4
AWG11606.1\|1475265_1475649_-	hypothetical protein	NA	NA	NA	NA
AWG11607.1\|1475641_1476718_-	DGQHR domain-containing protein	T1SBJ4	Salmonella_phage	2.8e-147	74.4
AWG11608.1\|1476845_1477631_-	hypothetical protein	A4JX52	Burkholderia_virus	2.9e-61	50.6
AWG11609.1\|1477630_1477930_-	hypothetical protein	K7PJS4	Enterobacterial_phage	1.1e-13	48.6
AWG11610.1\|1478558_1479254_-	helix-turn-helix transcriptional regulator	Q8HAA0	Salmonella_phage	2.7e-87	71.3
AWG11611.1\|1479351_1479594_+	XRE family transcriptional regulator	A0A1C9IHV8	Salmonella_phage	1.3e-25	80.3
AWG11612.1\|1479628_1480090_+	hypothetical protein	K7PJS5	Enterobacterial_phage	1.7e-69	88.2
AWG11613.1\|1480327_1480507_+	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	4.6e-15	73.1
AWG11614.1\|1480496_1481450_+	helix-turn-helix domain-containing protein	U5P0A0	Shigella_phage	6.1e-90	69.0
AWG11615.1\|1481446_1482256_+	DNA methylase	A0A1C9II58	Salmonella_phage	2.9e-109	68.9
AWG11616.1\|1482265_1482643_+	RusA family crossover junction endodeoxyribonuclease	A0A1C9IIA0	Salmonella_phage	2.3e-48	73.6
AWG11617.1\|1482655_1483636_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	7.6e-136	67.5
AWG11618.1\|1483649_1484228_+	DUF1133 domain-containing protein	A0A0U2S606	Escherichia_phage	7.6e-51	57.2
AWG11619.1\|1484447_1484873_+	tellurite/colicin resistance protein	Q71TK7	Escherichia_phage	1.9e-59	83.7
AWG11620.1\|1485523_1485919_+	hypothetical protein	K7PHB9	Enterobacterial_phage	2.6e-63	98.5
AWG11621.1\|1485905_1486187_+\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	3.9e-37	80.6
AWG11622.1\|1486186_1486816_+	endolysin	G8C7W0	Escherichia_phage	1.2e-105	90.9
AWG11623.1\|1486823_1487099_+	hypothetical protein	G8C7W1	Escherichia_phage	1.9e-23	66.3
AWG11624.1\|1487049_1487244_+	hypothetical protein	A0A286SGR9	Klebsiella_phage	2.7e-21	83.6
AWG11625.1\|1487300_1487960_-	hypothetical protein	NA	NA	NA	NA
AWG11626.1\|1488159_1488510_+	HNH endonuclease	A0A1B5FP94	Escherichia_phage	3.4e-46	73.7
AWG11627.1\|1488668_1489166_+\|terminase	phage terminase small subunit P27 family	K7PHI2	Enterobacteria_phage	2.5e-63	72.0
AWG11628.1\|1489169_1490921_+\|terminase	terminase large subunit	A0A1P8DTK0	Proteus_phage	6.7e-252	72.2
AWG11629.1\|1491068_1492295_+\|portal	phage portal protein	Q8SBI0	Shigella_phage	3.2e-208	85.3
AWG11630.1\|1492287_1492887_+\|head,protease	HK97 family phage prohead protease	Q8SBH9	Shigella_phage	1.0e-90	83.0
AWG11631.1\|1492896_1494135_+\|capsid	phage major capsid protein	Q8SBH8	Shigella_phage	6.8e-158	69.2
AWG11632.1\|1494212_1494530_+\|head,tail	phage gp6-like head-tail connector protein	A0A1W6JNZ5	Morganella_phage	4.8e-23	52.0
AWG11633.1\|1494538_1494877_+\|head,tail	head-tail adaptor protein	A0A2H4JHK5	uncultured_Caudovirales_phage	3.3e-38	67.9
AWG11634.1\|1494873_1495323_+	hypothetical protein	Q9MCS9	Enterobacteria_phage	6.7e-63	82.6
AWG11635.1\|1495319_1495667_+	DUF3168 domain-containing protein	K7PKL6	Enterobacterial_phage	2.8e-32	63.7
AWG11636.1\|1495723_1496428_+\|tail	phage tail protein	K7PHL2	Enterobacterial_phage	9.5e-80	66.5
AWG11637.1\|1496458_1496863_+\|tail	phage tail protein	Q9MCS5	Enterobacteria_phage	1.9e-32	56.2
AWG11638.1\|1496865_1497171_+	DUF4035 domain-containing protein	Q9MCS5	Enterobacteria_phage	4.7e-28	64.6
AWG11639.1\|1497244_1497478_+	hypothetical protein	K7PH16	Enterobacteria_phage	1.9e-08	47.2
AWG11640.1\|1497539_1500926_+\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	4.0e-301	57.5
AWG11641.1\|1500947_1501421_+	hypothetical protein	A0A286S298	Klebsiella_phage	1.1e-55	62.7
AWG11642.1\|1501407_1501884_+	DUF1833 domain-containing protein	A0A286S2B1	Klebsiella_phage	5.3e-50	64.6
AWG11643.1\|1501896_1502277_+	nitrite transporter	A0A286S2A6	Klebsiella_phage	2.0e-60	83.3
AWG11644.1\|1502273_1505351_+	kinase	A0A286S259	Klebsiella_phage	0.0e+00	62.2
AWG11645.1\|1508035_1509130_+	hypothetical protein	A0A248XD67	Klebsiella_phage	1.4e-178	86.5
AWG11646.1\|1509164_1510265_-	hypothetical protein	NA	NA	NA	NA
AWG11647.1\|1510420_1510741_+	hypothetical protein	K7PGV5	Enterobacterial_phage	1.1e-22	50.9
AWG11648.1\|1510951_1511881_-	hypothetical protein	E7DYY8	Enterobacteria_phage	6.7e-134	81.4
AWG11649.1\|1512170_1512932_+	phospholipid-binding lipoprotein MlaA	NA	NA	NA	NA
AWG11650.1\|1512993_1514322_-	long-chain fatty acid transporter FadL	NA	NA	NA	NA
AWG11651.1\|1514689_1514974_+	DUF406 domain-containing protein	NA	NA	NA	NA
AWG11652.1\|1515133_1516444_+	acetyl-CoA C-acyltransferase FadI	NA	NA	NA	NA
AWG11653.1\|1516443_1518588_+	fatty acid oxidation complex subunit alpha FadJ	NA	NA	NA	NA
AWG11654.1\|1518797_1519283_+	phosphohistidine phosphatase SixA	NA	NA	NA	NA
AWG11655.1\|1519303_1519855_-	endonuclease SmrB	NA	NA	NA	NA
AWG11656.1\|1520022_1520955_+	50S ribosomal protein L3 N(5)-glutamine methyltransferase	NA	NA	NA	NA
AWG11657.1\|1520996_1522082_+	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-89	46.6
AWG11658.1\|1522084_1522909_+	penicillin-insensitive murein endopeptidase	NA	NA	NA	NA
AWG11659.1\|1522908_1523718_+	hypothetical protein	NA	NA	NA	NA
AWG11660.1\|1523717_1524266_+	elongation factor P hydroxylase	NA	NA	NA	NA
AWG15039.1\|1524297_1524579_+	YfcL family protein	NA	NA	NA	NA
AWG15040.1\|1524640_1526629_-\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA
AWG11661.1\|1526787_1528008_+	beta-ketoacyl-[acyl-carrier-protein] synthase I	NA	NA	NA	NA
AWG11662.1\|1528217_1529393_+	arabinose transporter	NA	NA	NA	NA
AWG11663.1\|1529479_1530457_-	flagella biosynthesis regulator Flk	NA	NA	NA	NA
AWG11664.1\|1530567_1531704_+	4-phosphoerythronate dehydrogenase PdxB	A0A2R8FDS8	Brazilian_cedratvirus	1.6e-20	27.8
AWG11665.1\|1531767_1532781_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
AWG11666.1\|1532780_1533593_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA

DBSCAN-SWA_2

1732515 : 1739420

Planktothrix_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWG15047.1\|1732515_1733379_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.7e-10	27.5
AWG11836.1\|1733389_1734163_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.9e-26	36.7
AWG15048.1\|1734403_1735297_-	lipid kinase YegS	A0A1V0SBJ0	Catovirus	6.1e-15	29.8
AWG11837.1\|1735542_1736904_-	U32 family peptidase	Q6DW11	Phage_TP	1.8e-207	94.8
AWG11838.1\|1737222_1737945_-	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	8.3e-31	33.2
AWG11839.1\|1737941_1739420_-	two-component system sensor histidine kinase BaeA	W8CYF6	Bacillus_phage	8.5e-30	28.3

DBSCAN-SWA_3

2703817 : 2714704

Escherichia_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWG12736.1\|2703817_2706925_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	59.6
AWG12737.1\|2706979_2708245_+	MFS transporter	NA	NA	NA	NA
AWG12738.1\|2708275_2709364_-	chromosome segregation protein SMC	A0A077SLJ9	Escherichia_phage	1.8e-210	99.7
AWG12739.1\|2709450_2709711_-	hypothetical protein	A0A077SK33	Escherichia_phage	5.4e-41	98.8
AWG12740.1\|2710008_2710869_+	class A beta-lactamase SHV-28	A0A077SL40	Escherichia_phage	1.7e-155	99.3
AWG12741.1\|2710889_2711651_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
AWG12742.1\|2711911_2712814_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	2.6e-159	99.7
AWG12743.1\|2712825_2714091_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	3.9e-233	99.5
AWG12744.1\|2714083_2714704_+	aldolase	A0A077SK32	Escherichia_phage	8.0e-115	100.0

DBSCAN-SWA_4

3378686 : 3388160

Brazilian_cedratvirus(16.67%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWG13339.1\|3378686_3380408_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	1.5e-14	34.3
AWG13340.1\|3380452_3381154_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
AWG13341.1\|3381507_3381726_+	translation initiation factor IF-1	NA	NA	NA	NA
AWG13342.1\|3381856_3384136_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.6e-165	42.0
AWG13343.1\|3384166_3384484_-\|protease	ATP-dependent Clp protease adaptor ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
AWG13344.1\|3384809_3385031_+	cold shock domain protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
AWG13345.1\|3384985_3385168_-	hypothetical protein	NA	NA	NA	NA
AWG13346.1\|3385107_3387048_-	MacB family efflux pump subunit	G9BWD6	Planktothrix_phage	5.0e-38	41.0
AWG13347.1\|3387044_3388160_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP026497

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP026496

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. CP026495

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection