CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP029156	Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence	1 crisprs	NA	0	1	2	0
CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	0 crisprs	NA	0	0	2	0
CP029154	Clostridioides difficile strain CD161 chromosome, complete genome	11 crisprs	cas14j,PD-DExK,WYL,cas3,DEDDh,DinG,csa3,cas14k,cas5,cas7,cas6,c2c9_V-U4,RT	3	35	11	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP029156_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029156_1

3830-3928

Orphan

Consensus_repeat	Method
GTCACAAATCGGACATTTTTTAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029156_1

>merge|CP029156|1|3830-3928|CRISPRCasFinder
GACACAAAACAGACATAAATTGGTCACAAATCGGACATTTTTTAGACACAAAACAGACATAAATCGGTTTAAAATCGTCACAAATCGGACATTTTTATA

>CP029156|1|1|3830-3928|CRISPRCasFinder
GACACAAAACAGACATAAATTGG	TCACAAATCGGACATTTTTTAGACACAAAACAGACATAAATCGGTTTAAAATC
GTCACAAATCGGACATTTTTATA

Protein	Signature genes	Signature genes Name	Protein_function
CP029156.1\|AWH83533.1\|6365_6902_-\|LemA-family-protein	unknown	unknown	gnl\|CDD\|224618
CP029156.1\|AWH83526.1\|1914_2373_-\|resolvase	unknown	unknown	gnl\|CDD\|379233
CP029156.1\|AWH83534.1\|6901_7228_-\|hypothetical-protein	unknown	unknown	unknown
CP029156.1\|AWH83535.1\|7417_8002_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
CP029156.1\|AWH83536.1\|7979_8357_-\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|239942
CP029156.1\|AWH83530.1\|4753_5239_-\|hypothetical-protein	unknown	unknown	unknown
CP029156.1\|AWH83538.1\|8592_9297_-\|hypothetical-protein	unknown	unknown	unknown
CP029156.1\|AWH83591.1\|3235_3781_-\|hypothetical-protein	unknown	unknown	unknown
CP029156.1\|AWH83529.1\|4476_4734_-\|hypothetical-protein	unknown	unknown	unknown
CP029156.1\|AWH83531.1\|5262_5523_-\|hypothetical-protein	unknown	unknown	unknown
CP029156.1\|AWH83532.1\|5547_6354_-\|hypothetical-protein	unknown	unknown	unknown
CP029156.1\|AWH83537.1\|8353_8536_-\|hypothetical-protein	unknown	unknown	unknown
CP029156.1\|AWH83527.1\|2587_3232_-\|recombinase	unknown	unknown	gnl\|CDD\|271192

Protein	Function_ID	Function_description	E-value
CP029156.1\|AWH83533.1\|6365_6902_-\|LemA-family-protein	gnl\|CDD\|224618	COG1704, LemA, Uncharacterized conserved protein [Function unknown].	5.41012e-45
CP029156.1\|AWH83526.1\|1914_2373_-\|resolvase	gnl\|CDD\|379233	pfam13518, HTH_28, Helix-turn-helix domain. This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.	0.000256426
CP029156.1\|AWH83535.1\|7417_8002_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	8.00887e-13
CP029156.1\|AWH83527.1\|2587_3232_-\|recombinase	gnl\|CDD\|271192	cd01192, INT_C_like_3, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	3.48157e-41
CP029156.1\|AWH83536.1\|7979_8357_-\|single-stranded-DNA-binding-protein	gnl\|CDD\|239942	cd04496, SSB_OBF, SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.	1.66685e-28

>CP029156.1|AWH83591.1|3235_3781_-|hypothetical-protein
MAWNLRSKSFLLSREVLKIKRDITEEISSAAYVPDNLKYYDNVMKETPGMYGRECSLDFIKKKQEKLLKLKKKVKKNYDSNINKIDSYLKILEESIIDESDHVELVVFKLYLQLENVVKVTETVNDLGFRIKTNTYARERKYSTNDITSIITDPFANVVEDLKILVQDRQRKNYHGNKECF
>CP029156.1|AWH83527.1|2587_3232_-|recombinase
MEAHSGQKVNPIKDIEDVFRLLNFLEEWNERNYLLALFGMCTGLRIGDILALKVADVTDVKLDKKGKKIRVSKDWIRVIEEKRDYDREVFLSDVIKSAIENYTQDKPGEEFLFKSGKRKKFNRPIQTRQAGRIIKGAAEKVGIKENVATHSLRKTFARHIYDEEENKTYALELIRKILGHKTIEMTRRYIGIDKDEEVKAITKFTNKLKKRKRN
>CP029156.1|AWH83526.1|1914_2373_-|resolvase
MDVNEVEIIDSSYEKGKELTEDQCNMVTLLITGTTVTETARIIGVNRKTIYNWMNKEHVRKEMDRRKQELTNQGNLMILKDLDSYINNIKELASDKSDKRVMLAANQYLINRIYGTPTSTVVQAEDNSVGMGMDATEIEAAIAKIRIRTSKK
>CP029156.1|AWH83529.1|4476_4734_-|hypothetical-protein
MLIEVTENNRELKVGDIVEINGGNKLYMILSLKETIGGYVIINMQNGYGSFGAYKSLSQLELDLKVRGYKLYSSDDYKLQLVPRE
>CP029156.1|AWH83530.1|4753_5239_-|hypothetical-protein
MDLKLISSIPNWKVEDQLAKIDEEVTEFKNAIDTGITKDIIAEGLDVCQTILTMFQVLEIENYITEGVETHNKKLNGRGWDLKEIGDDILNLIKNSMINELINMNKKLKCLDEKEFNAKIQFLDVDKLWNLCMPLVNLSTIKGVNESIDEMKMGEFLKNIN
>CP029156.1|AWH83531.1|5262_5523_-|hypothetical-protein
MKCKVYHAIKNIKDANELIDRFETENIFFELNDIDNENVLNGEMDLTDIEDIASLQFILDGDLFIFSSCDEMIFMNKYTQKELGLQ
>CP029156.1|AWH83532.1|5547_6354_-|hypothetical-protein
MKFKTFEITKREFLVSIIIACMMIVLGFFIDDKVQSKFLEDNERYYKATKINNDKDLFDYAMETSAGDSLISGRFKSVDSVSIEELKGDYWFIERTEEKYTMHTRVVTTKDSKGHSHKYTETYWTWDYHDSIEKKCNKFNFMGKEFDAKVITNLSKERLALKKDIFKNNNLKIKGNYAYINNKRRYYYEVIPKEFNGTMYANLKNNTIANPADKNIKVFKGESIQNVLENNNFNTGFFKVVFWIIWILITTIIIYVFYYLKNDWLEDK
>CP029156.1|AWH83533.1|6365_6902_-|LemA-family-protein
MKKTLIIVGVVISILIMFACLFLVTKNKAIDLEEQVQSATASVEVQEKRRIDLIKNIVDCVKDYAKYENRTLKEVTDMRVSANDESIKEAKLNIQAVAEKYPDLKANENYKQLMSELSITENMIAQHRENYNMQVRNYNKYIRKFPANLILNSMGYEKIESKYTEYKAKEDAPQNLFD
>CP029156.1|AWH83534.1|6901_7228_-|hypothetical-protein
MSCVIKCDFCGETIAEILNIKVFRIDDEGNIMSIGKDVCGKCYDRLFGSNLNKKMTNYEKIKNMSKIEMAEFLANGGSGCTSCAYDFQECLGGCLEGRKKWLESEAMK
>CP029156.1|AWH83535.1|7417_8002_-|sigma-70-family-RNA-polymerase-sigma-factor
MMKIFHFKLDGDYVRSLEERNKLFEDNINLVHFIINRYFKSFLRRYPYLKEDLFQEGYIGLYKTTCCFDESKGKFSTIAFSYISGHLKRFTTGYVKKHYRNDIDSFEKCIYRDNYGEEIRIEDRLAGNENVDIENVRVIRSCIKRSEIKDIQKIVCLREKGYTQQEISKVLGTSQTSIYRRLKKLKTEINILGK
>CP029156.1|AWH83536.1|7979_8357_-|single-stranded-DNA-binding-protein
MNNVVLVGRLARDPELRYIPEYGTPVATFALAVDRGYTKKDGTREVDFIPIEVMGGSAEFCANYLAKGRMVSIQGQIRIEKYEKDGEKKTFTKVRTKIVNALDHKPKDEEKEISFQVLDDEDIPF
>CP029156.1|AWH83537.1|8353_8536_-|hypothetical-protein
MKMISHMNILERAEFTDKIANAIMSANKEIERGCAFNEAVEIVKQMEYRENKYNEGDIAI
>CP029156.1|AWH83538.1|8592_9297_-|hypothetical-protein
MIRNAMEYLVKLGKRETVCVDGFKYTTDALEIIKEPKANELEITTLSGLVDYIKSGIDHKADELLLIQVLTPRKVLLKSPLRKNRDREIYIECVALLPEKRFDRPLDLDSFNIMLQSAFIKNNDRDTLLKIAGNIQESTVKNVGDDGVSQSVTIKTGVASVSEAIVPNRVKLIPYRTFQEVEQPESEFIFRMSTGPAAGLYEADGGAWKNQAMLNIKAYLQEELKDFKNVNIIA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Identity
CP029156_1	1.1\|3853\|53\|CP029156\|CRISPRCasFinder	3853-3905	53	NZ_CP020425	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence	40333-40385	1.0
CP029156_1	1.1\|3853\|53\|CP029156\|CRISPRCasFinder	3853-3905	53	FN668942	Clostridium difficile BI1 plasmid pCDBI1, complete sequence	39066-39118	1.0
CP029156_1	1.1\|3853\|53\|CP029156\|CRISPRCasFinder	3853-3905	53	NZ_CP011969	Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence	35655-35707	1.0
CP029156_1	1.1\|3853\|53\|CP029156\|CRISPRCasFinder	3853-3905	53	NZ_CP029156	Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence	3853-3905	1.0
CP029156_1	1.1\|3853\|53\|CP029156\|CRISPRCasFinder	3853-3905	53	NZ_CP029153	Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence	46490-46542	1.0

1. spacer 1.1|3853|53|CP029156|CRISPRCasFinder matches to NZ_CP020425 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

tcacaaatcggacattttttagacacaaaacagacataaatcggtttaaaatc	CRISPR spacer
tcacaaatcggacattttttagacacaaaacagacataaatcggtttaaaatc	Protospacer
*****************************************************

2. spacer 1.1|3853|53|CP029156|CRISPRCasFinder matches to FN668942 (Clostridium difficile BI1 plasmid pCDBI1, complete sequence) position: , mismatch: 0, identity: 1.0

tcacaaatcggacattttttagacacaaaacagacataaatcggtttaaaatc	CRISPR spacer
tcacaaatcggacattttttagacacaaaacagacataaatcggtttaaaatc	Protospacer
*****************************************************

3. spacer 1.1|3853|53|CP029156|CRISPRCasFinder matches to NZ_CP011969 (Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

tcacaaatcggacattttttagacacaaaacagacataaatcggtttaaaatc	CRISPR spacer
tcacaaatcggacattttttagacacaaaacagacataaatcggtttaaaatc	Protospacer
*****************************************************

4. spacer 1.1|3853|53|CP029156|CRISPRCasFinder matches to NZ_CP029156 (Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tcacaaatcggacattttttagacacaaaacagacataaatcggtttaaaatc	CRISPR spacer
tcacaaatcggacattttttagacacaaaacagacataaatcggtttaaaatc	Protospacer
*****************************************************

5. spacer 1.1|3853|53|CP029156|CRISPRCasFinder matches to NZ_CP029153 (Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

tcacaaatcggacattttttagacacaaaacagacataaatcggtttaaaatc	CRISPR spacer
tcacaaatcggacattttttagacacaaaacagacataaatcggtttaaaatc	Protospacer
*****************************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1914 : 17857

Clostridium_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWH83526.1\|1914_2373_-	resolvase	A0A1V0E032	Clostridioides_phage	3.9e-58	77.6
AWH83527.1\|2587_3232_-	recombinase	A0A1V0E036	Clostridioides_phage	1.6e-113	98.1
AWH83591.1\|3235_3781_-	hypothetical protein	A0A1V0E034	Clostridioides_phage	2.4e-75	83.9
AWH83528.1\|3923_4367_-	RNA polymerase subunit sigma	A0A1V0E028	Clostridioides_phage	9.3e-49	72.4
AWH83529.1\|4476_4734_-	hypothetical protein	NA	NA	NA	NA
AWH83530.1\|4753_5239_-	hypothetical protein	Q24LD1	Clostridium_phage	3.3e-15	57.3
AWH83531.1\|5262_5523_-	hypothetical protein	NA	NA	NA	NA
AWH83532.1\|5547_6354_-	hypothetical protein	NA	NA	NA	NA
AWH83533.1\|6365_6902_-	LemA family protein	A0A1X9IGG1	Lactococcus_phage	7.6e-29	39.6
AWH83534.1\|6901_7228_-	hypothetical protein	NA	NA	NA	NA
AWH83535.1\|7417_8002_-	sigma-70 family RNA polymerase sigma factor	S5MNV1	Brevibacillus_phage	1.8e-07	28.9
AWH83536.1\|7979_8357_-	single-stranded DNA-binding protein	E2ELN0	Clostridium_phage	1.1e-37	57.0
AWH83537.1\|8353_8536_-	hypothetical protein	NA	NA	NA	NA
AWH83538.1\|8592_9297_-	hypothetical protein	A0A0A7RUC6	Clostridium_phage	2.2e-68	57.1
AWH83539.1\|9348_9735_-	hypothetical protein	A0A0A7RUF3	Clostridium_phage	5.6e-18	47.0
AWH83540.1\|10105_11434_-	DNA helicase	A0A2H4J8K1	uncultured_Caudovirales_phage	9.3e-20	26.8
AWH83541.1\|11455_11773_-	hypothetical protein	NA	NA	NA	NA
AWH83542.1\|11910_12099_+	hypothetical protein	NA	NA	NA	NA
AWH83543.1\|12091_12352_-	hypothetical protein	NA	NA	NA	NA
AWH83544.1\|12514_12727_+	hypothetical protein	NA	NA	NA	NA
AWH83545.1\|12745_12964_-	hypothetical protein	A0A090D836	Clostridium_phage	1.7e-08	46.9
AWH83546.1\|12990_13176_-	hypothetical protein	NA	NA	NA	NA
AWH83547.1\|13203_13923_-	helix-turn-helix domain-containing protein	A0A1V0E018	Clostridioides_phage	7.0e-30	57.8
AWH83548.1\|13951_14158_-	hypothetical protein	E2ELM0	Clostridium_phage	2.7e-11	49.3
AWH83549.1\|14491_14866_+	XRE family transcriptional regulator	A0A1V0E015	Clostridioides_phage	2.1e-46	76.6
AWH83550.1\|15499_15868_+	XRE family transcriptional regulator	E2ELL8	Clostridium_phage	8.5e-48	82.6
AWH83551.1\|16635_17019_+	BlaI/MecI/CopY family transcriptional regulator	A0A0A8WJP7	Clostridium_phage	5.6e-26	45.7
AWH83552.1\|17167_17857_-	HTH domain-containing protein	E2ELL5	Clostridium_phage	1.7e-41	41.7

DBSCAN-SWA_2

21157 : 47997

Clostridioides_phage(56.25%)

portal,holin,head,plate,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWH83556.1\|21157_21310_+	hypothetical protein	J9QED5	Clostridium_phage	1.6e-05	53.2
AWH83592.1\|21690_22005_+	hypothetical protein	NA	NA	NA	NA
AWH83557.1\|22039_22498_+	hypothetical protein	NA	NA	NA	NA
AWH83558.1\|22746_22950_+	hypothetical protein	NA	NA	NA	NA
AWH83559.1\|22969_23875_+	ATPase	Q0SPH6	Clostridium_phage	5.2e-22	28.6
AWH83560.1\|23957_24473_+	hypothetical protein	A0A0A8WEM4	Clostridium_phage	7.8e-23	35.6
AWH83561.1\|24483_24819_-	CopY family transcriptional regulator	A0A0A8WFI6	Clostridium_phage	3.7e-18	45.0
AWH83562.1\|24956_26063_-	DNA (cytosine-5-)-methyltransferase	A0A0A8WIK9	Clostridium_phage	6.2e-126	62.7
AWH83563.1\|26134_26950_-	cell wall hydrolase	Q24LG3	Clostridium_phage	1.3e-149	96.3
AWH83564.1\|26949_27207_-\|holin	holin	A0A0K2SUI8	Clostridium_phage	5.4e-41	96.5
AWH83565.1\|27210_27501_-	hypothetical protein	A0A0A8WIF5	Clostridium_phage	6.3e-46	100.0
AWH83566.1\|27531_28098_-	hypothetical protein	A0A0A8WFF2	Clostridium_phage	8.5e-39	81.1
AWH83567.1\|28130_28313_-	hypothetical protein	A0A090D845	Clostridium_phage	1.4e-24	96.7
AWH83568.1\|28312_28606_-	hypothetical protein	A0A2R2ZGK0	Clostridioides_phage	6.6e-35	75.3
AWH83569.1\|30263_31265_-\|tail	phage tail protein	A0A090DCR2	Clostridium_phage	9.8e-139	86.5
AWH83570.1\|31265_31883_-	DUF2313 domain-containing protein	J9QD29	Clostridium_phage	3.6e-91	82.9
AWH83571.1\|31884_32937_-\|plate	baseplate protein J	A0A1V0DZY2	Clostridioides_phage	4.7e-176	90.3
AWH83572.1\|32929_33364_-	DUF2634 domain-containing protein	A0A1V0DZX2	Clostridioides_phage	6.5e-71	90.1
AWH83573.1\|33356_33689_-	DUF2577 domain-containing protein	J9QE86	Clostridium_phage	3.1e-49	87.0
AWH83593.1\|33702_35220_-	cell wall hydrolase	A0A1V0DZX6	Clostridioides_phage	6.7e-264	88.0
AWH83574.1\|35459_36095_-	LysM peptidoglycan-binding domain-containing protein	A0A1V0DZX0	Clostridioides_phage	2.5e-108	86.3
AWH83575.1\|36152_36629_-	DUF4352 domain-containing protein	NA	NA	NA	NA
AWH83576.1\|36675_40068_-\|tail	phage tail tape measure protein	A0A1V0DZX3	Clostridioides_phage	2.6e-175	57.4
AWH83577.1\|40247_40664_-\|portal	phage portal protein	A0A1V0DZX5	Clostridioides_phage	3.5e-58	81.2
AWH83578.1\|40679_41120_-\|portal	phage portal protein	A0A1V0DZX1	Clostridioides_phage	1.3e-63	77.5
AWH83579.1\|41135_42191_-\|tail	phage tail sheath protein	A0A1V0DZX4	Clostridioides_phage	5.6e-169	85.5
AWH83580.1\|42191_42641_-	hypothetical protein	A0A1V0DZX9	Clostridioides_phage	4.0e-68	89.3
AWH83581.1\|42649_43006_-	HK97 gp10 family phage protein	A0A1V0DZV8	Clostridioides_phage	5.7e-57	92.4
AWH83582.1\|43005_43353_-	hypothetical protein	A0A1V0DZW2	Clostridioides_phage	1.4e-55	89.6
AWH83583.1\|43364_43745_-	hypothetical protein	A0A1V0DZU9	Clostridioides_phage	1.9e-58	93.7
AWH83584.1\|43728_44001_-	hypothetical protein	A0A1V0DZV5	Clostridioides_phage	4.2e-28	75.3
AWH83585.1\|44014_44938_-	hypothetical protein	A0A1V0DZW0	Clostridioides_phage	9.6e-149	85.3
AWH83586.1\|44966_45569_-	DUF4355 domain-containing protein	A0A1V0DZW6	Clostridioides_phage	5.6e-73	72.9
AWH83587.1\|45594_45921_-	hypothetical protein	A0A1J1J9Q7	Escherichia_phage	1.2e-05	30.6
AWH83588.1\|45980_46742_-\|head	phage head morphogenesis protein	A0A1V0DZW9	Clostridioides_phage	7.8e-112	87.0
AWH83589.1\|46719_47997_-\|portal	phage portal protein	A0A1V0DZW8	Clostridioides_phage	1.7e-215	87.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP029155

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

92 : 72534

Clostridium_phage(53.57%)

integrase

attL 1340:1361|attR 58639:58660

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWH83377.1\|92_695_-	hypothetical protein	A0A0A8WF28	Clostridium_phage	2.3e-106	94.0
AWH83521.1\|1239_1500_-	DUF5052 domain-containing protein	A0A2R2ZGR4	Clostridioides_phage	5.8e-19	56.7
1340:1361	attL	NA	NA	NA	NA
AWH83378.1\|1599_2052_-	hypothetical protein	A0A2R2ZGR6	Clostridioides_phage	2.2e-74	99.2
AWH83379.1\|2063_2414_-	hypothetical protein	A0A2R2ZGT0	Clostridioides_phage	3.0e-58	97.4
AWH83380.1\|2440_2623_-	hypothetical protein	A0A2R2ZGR1	Clostridioides_phage	3.7e-28	100.0
AWH83381.1\|2615_2825_-	hypothetical protein	A0A2R2ZGQ9	Clostridioides_phage	1.1e-31	98.6
AWH83382.1\|3045_3276_-	hypothetical protein	A0A2R2ZGQ8	Clostridioides_phage	1.1e-37	100.0
AWH83383.1\|3293_3656_-	hypothetical protein	A0A2R2ZGR5	Clostridioides_phage	5.8e-65	100.0
AWH83384.1\|3846_4026_-	hypothetical protein	A0A2R2ZGS3	Clostridioides_phage	3.4e-26	100.0
AWH83385.1\|4392_5646_-	RNA-splicing ligase RtcB	A0A2R2ZGS4	Clostridioides_phage	2.3e-225	100.0
AWH83386.1\|5698_6058_-	hypothetical protein	A0A2R2ZGS5	Clostridioides_phage	2.0e-62	100.0
AWH83387.1\|6077_6545_-	hypothetical protein	A0A2R2ZGU1	Clostridioides_phage	5.7e-81	100.0
AWH83388.1\|6736_7087_-	hypothetical protein	A0A2R2ZGR8	Clostridioides_phage	2.2e-61	100.0
AWH83389.1\|7659_8106_-	hypothetical protein	A0A2R2ZGS9	Clostridioides_phage	2.7e-80	100.0
AWH83390.1\|8303_8684_-	hypothetical protein	A0A2R2ZGS6	Clostridioides_phage	3.2e-66	99.2
AWH83391.1\|8719_9187_-	hypothetical protein	A0A2R2ZGT1	Clostridioides_phage	9.3e-84	100.0
AWH83392.1\|9215_9326_-	acyltransferase	A0A2R2ZGT2	Clostridioides_phage	5.8e-13	100.0
AWH83393.1\|9312_9657_-	hypothetical protein	A0A2R2ZGT3	Clostridioides_phage	2.9e-58	100.0
AWH83394.1\|10076_10445_-	hypothetical protein	A0A2R2ZGV1	Clostridioides_phage	1.0e-61	100.0
AWH83395.1\|10465_11002_-	hypothetical protein	A0A2R2ZGS8	Clostridioides_phage	1.6e-103	100.0
AWH83396.1\|11021_11417_-	hypothetical protein	A0A2R2ZGS7	Clostridioides_phage	4.5e-63	100.0
AWH83397.1\|11420_12434_-	hypothetical protein	A0A2R2ZGT9	Clostridioides_phage	1.0e-196	97.9
AWH83398.1\|12793_13156_-	hypothetical protein	A0A2R2ZGN2	Clostridioides_phage	1.1e-39	73.4
AWH83399.1\|13193_15374_-	adenosylcobalamin-dependent ribonucleoside-diphosphate reductase	A0A2R2ZGN9	Clostridioides_phage	0.0e+00	95.3
AWH83400.1\|15412_15916_-	hypothetical protein	A0A0A8WI18	Clostridium_phage	1.8e-85	98.8
AWH83401.1\|16016_16418_-	DNA ligase	A0A0A8WIS9	Clostridium_phage	3.4e-66	99.2
AWH83402.1\|16471_16822_-	hypothetical protein	NA	NA	NA	NA
AWH83403.1\|16983_17994_-	nucleotidyltransferase	H7BUW2	unidentified_phage	8.8e-79	46.9
AWH83404.1\|18060_19173_-	hypothetical protein	A0A1B1IPS3	uncultured_Mediterranean_phage	9.2e-13	27.2
AWH83522.1\|19175_19601_-	DUF1653 domain-containing protein	NA	NA	NA	NA
AWH83523.1\|19916_20840_-	hypothetical protein	H7BVI6	unidentified_phage	7.6e-37	51.4
AWH83405.1\|20891_21212_-	hypothetical protein	A0A0A8WJJ0	Clostridium_phage	3.5e-58	95.3
AWH83406.1\|21271_21661_-	hypothetical protein	A0A0A8WEK3	Clostridium_phage	1.2e-68	97.7
AWH83407.1\|21698_22103_-	hypothetical protein	A0A0A8WI20	Clostridium_phage	7.8e-71	97.8
AWH83408.1\|22916_23168_-	hypothetical protein	NA	NA	NA	NA
AWH83409.1\|23278_23545_-	hypothetical protein	NA	NA	NA	NA
AWH83410.1\|23688_24231_-	RNA 2'-phosphotransferase	A0A0A8WJJ2	Clostridium_phage	2.2e-92	91.1
AWH83411.1\|24423_24846_-	DUF3850 domain-containing protein	A0A0A8WI22	Clostridium_phage	2.2e-76	100.0
AWH83412.1\|24869_25103_-	hypothetical protein	A0A0A8WIT3	Clostridium_phage	4.5e-39	98.7
AWH83413.1\|25262_25799_-	hypothetical protein	A0A0A8WJJ4	Clostridium_phage	3.0e-86	98.8
AWH83414.1\|25822_26047_-	hypothetical protein	A0A0A8WEL1	Clostridium_phage	7.2e-34	97.3
AWH83415.1\|26110_26905_-	hypothetical protein	A0A0A8WI24	Clostridium_phage	5.6e-129	85.1
AWH83416.1\|27242_27575_+	XRE family transcriptional regulator	A0A0A8WEL4	Clostridium_phage	1.0e-12	36.9
AWH83417.1\|28048_28387_+	XRE family transcriptional regulator	A0A0A8WEL4	Clostridium_phage	9.2e-57	100.0
AWH83418.1\|29300_30479_-	hypothetical protein	A0A0A8WF68	Clostridium_phage	6.0e-212	96.9
AWH83419.1\|30554_30821_-	helix-turn-helix domain containing protein	A0A0A8WJJ9	Clostridium_phage	6.4e-37	86.4
AWH83420.1\|31294_32863_-	hypothetical protein	A0A0A8WI31	Clostridium_phage	1.5e-295	100.0
AWH83421.1\|32867_33794_-	hypothetical protein	A0A0A8WIU3	Clostridium_phage	4.5e-170	99.4
AWH83422.1\|33925_34498_-\|integrase	integrase	A0A2R2ZHA6	Clostridioides_phage	2.9e-87	87.9
AWH83423.1\|34606_34789_-	hypothetical protein	NA	NA	NA	NA
AWH83424.1\|34965_35457_-	XRE family transcriptional regulator	A0A0A8WJK5	Clostridium_phage	7.6e-28	67.3
AWH83425.1\|35468_36893_-	hypothetical protein	A0A2R2ZHF2	Clostridioides_phage	7.6e-177	71.5
AWH83426.1\|36989_37553_-	hypothetical protein	NA	NA	NA	NA
AWH83427.1\|37705_38203_-	hypothetical protein	A0A0A8WF85	Clostridium_phage	2.0e-84	94.5
AWH83428.1\|38407_38659_-	hypothetical protein	NA	NA	NA	NA
AWH83429.1\|38809_39130_-	hypothetical protein	NA	NA	NA	NA
AWH83430.1\|39434_40046_-	hypothetical protein	A0A2R2ZHC6	Clostridioides_phage	4.2e-116	99.5
AWH83431.1\|40107_40344_-	hypothetical protein	A0A2R2ZHE8	Clostridioides_phage	1.8e-35	94.9
AWH83432.1\|40569_40827_-	hypothetical protein	A0A2R2ZGX6	Clostridioides_phage	2.8e-42	98.8
AWH83433.1\|40982_41177_-	XRE family transcriptional regulator	A0A0A8WF92	Clostridium_phage	6.1e-13	61.9
AWH83434.1\|41274_41586_-	hypothetical protein	A0A2R2ZGW8	Clostridioides_phage	1.2e-13	79.8
AWH83435.1\|41876_42080_-	XRE family transcriptional regulator	A0A0A8WF92	Clostridium_phage	2.6e-14	67.2
AWH83436.1\|42176_42479_-	hypothetical protein	NA	NA	NA	NA
AWH83437.1\|42492_42795_-	hypothetical protein	A0A2R2ZGZ0	Clostridioides_phage	7.8e-07	100.0
AWH83438.1\|43372_43684_+	XRE family transcriptional regulator	A0A0A8WIV9	Clostridium_phage	2.2e-49	100.0
AWH83439.1\|43897_44089_-	XRE family transcriptional regulator	A0A0A8WF95	Clostridium_phage	1.2e-26	100.0
AWH83440.1\|44996_45185_+	hypothetical protein	A0A0A8WEP6	Clostridium_phage	1.1e-27	100.0
AWH83441.1\|45606_46521_+	hypothetical protein	A0A0A8WI45	Clostridium_phage	9.2e-168	99.3
AWH83442.1\|46533_46806_+	hypothetical protein	A0A0A8WIW1	Clostridium_phage	4.1e-39	91.1
AWH83443.1\|47078_47942_+	hypothetical protein	A0A0A8WF99	Clostridium_phage	9.9e-164	99.0
AWH83444.1\|48119_48368_+	hypothetical protein	A0A0A8WEQ0	Clostridium_phage	2.8e-39	98.8
AWH83445.1\|48370_49813_+	hypothetical protein	A0A0A8WI47	Clostridium_phage	1.7e-264	99.6
AWH83446.1\|49946_50225_+	hypothetical protein	A0A0A8WIW3	Clostridium_phage	1.2e-41	100.0
AWH83447.1\|50315_50933_+	hypothetical protein	A0A0A8WFA1	Clostridium_phage	1.5e-105	99.5
AWH83448.1\|51302_51491_+	hypothetical protein	A0A2R2ZGZ1	Clostridioides_phage	2.9e-20	79.0
AWH83449.1\|51567_52767_+	hypothetical protein	A0A0A8WJL5	Clostridium_phage	2.7e-220	96.7
AWH83450.1\|52897_53797_+	hypothetical protein	A0A0A8WEC3	Clostridium_phage	6.9e-168	99.0
AWH83451.1\|53786_55535_+	hypothetical protein	A0A0A8WHX2	Clostridium_phage	0.0e+00	99.8
AWH83452.1\|55551_57030_+	hypothetical protein	A0A0A8WIM8	Clostridium_phage	1.4e-274	99.6
AWH83453.1\|57032_57224_+	hypothetical protein	A0A0A8WEW4	Clostridium_phage	9.5e-27	98.4
AWH83454.1\|57230_58664_+	hypothetical protein	A0A0A8WJD7	Clostridium_phage	1.7e-264	97.5
58639:58660	attR	NA	NA	NA	NA
AWH83455.1\|58678_59176_+	hypothetical protein	A0A0A8WEC6	Clostridium_phage	7.1e-90	100.0
AWH83456.1\|59264_60275_+	hypothetical protein	A0A0A8WHX4	Clostridium_phage	1.7e-191	100.0
AWH83457.1\|60327_60960_+	hypothetical protein	A0A0A8WIN0	Clostridium_phage	8.7e-109	98.6
AWH83458.1\|60974_61604_+	hypothetical protein	A0A0A8WEW6	Clostridium_phage	7.1e-111	98.6
AWH83459.1\|61605_62595_+	hypothetical protein	A0A0A8WJD9	Clostridium_phage	4.3e-179	94.8
AWH83460.1\|62609_63104_+	hypothetical protein	A0A2R2ZH01	Clostridioides_phage	3.3e-79	100.0
AWH83461.1\|63103_63907_+	hypothetical protein	A0A2R2ZGH2	Clostridioides_phage	3.3e-137	93.6
AWH83462.1\|63946_64765_+	hypothetical protein	A0A2R2ZGH3	Clostridioides_phage	2.3e-122	82.7
AWH83463.1\|64863_65649_+	hypothetical protein	A0A0A8WEX1	Clostridium_phage	3.6e-144	96.6
AWH83464.1\|65664_65955_+	hypothetical protein	NA	NA	NA	NA
AWH83465.1\|65984_66434_+	hypothetical protein	A0A2R2ZGI8	Clostridioides_phage	1.0e-66	91.3
AWH83466.1\|66434_66875_+	hypothetical protein	A0A0A8WED2	Clostridium_phage	2.7e-77	96.6
AWH83467.1\|66965_67340_+	YHYH domain-containing protein	NA	NA	NA	NA
AWH83468.1\|67643_68537_+	hypothetical protein	NA	NA	NA	NA
AWH83469.1\|69306_72534_+	restriction endonuclease subunit M	A0A2R2ZGH5	Clostridioides_phage	0.0e+00	99.7

DBSCAN-SWA_2

85436 : 130274

Clostridioides_phage(57.14%)

transposase,integrase,protease,tail

attL 99149:99168|attR 116374:116393

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWH83474.1\|85436_87365_+\|tail	tail fiber domain-containing protein	A0A2R2ZGK4	Clostridioides_phage	0.0e+00	100.0
AWH83475.1\|87533_89609_+\|tail	phage tail protein	A0A2R2ZGL7	Clostridioides_phage	9.2e-224	99.6
AWH83476.1\|89625_94509_+	hypothetical protein	A0A2R2ZGK2	Clostridioides_phage	0.0e+00	99.9
AWH83477.1\|94522_94849_+	hypothetical protein	A0A2R2ZGK3	Clostridioides_phage	8.0e-50	100.0
AWH83478.1\|94927_95257_+	hypothetical protein	A0A2R2ZGK9	Clostridioides_phage	9.0e-49	99.1
AWH83479.1\|95274_96999_+	hypothetical protein	A0A2R2ZGJ5	Clostridioides_phage	1.9e-219	79.1
AWH83480.1\|97012_97306_+	hypothetical protein	A0A2R2ZGK0	Clostridioides_phage	7.5e-47	100.0
AWH83481.1\|97305_97488_+	hypothetical protein	A0A2R2ZGL0	Clostridioides_phage	7.7e-26	100.0
AWH83482.1\|97613_98429_+	N-acetylmuramoyl-L-alanine amidase	A0A2R2ZGL3	Clostridioides_phage	6.1e-155	100.0
AWH83483.1\|98440_99058_+	cell surface protein	A0A2R2ZGL8	Clostridioides_phage	3.1e-119	100.0
AWH83484.1\|99069_99321_+	hypothetical protein	A0A2R2ZGL6	Clostridioides_phage	6.4e-39	100.0
99149:99168	attL	NA	NA	NA	NA
AWH83485.1\|99321_99633_+	hypothetical protein	A0A2R2ZGM7	Clostridioides_phage	2.2e-49	100.0
AWH83486.1\|99667_100603_+\|integrase	site-specific integrase	A0A2R2ZGL2	Clostridioides_phage	4.8e-180	100.0
AWH83487.1\|100873_101227_+	XRE family transcriptional regulator	A0A2R2ZGL4	Clostridioides_phage	1.6e-56	100.0
AWH83524.1\|101358_101685_+	transcriptional regulator	A0A2R2ZGM0	Clostridioides_phage	1.9e-51	100.0
AWH83488.1\|101839_103102_+	cell wall-binding repeat-containing protein	A0A2R2ZGK6	Clostridioides_phage	2.5e-232	100.0
AWH83525.1\|103375_103591_+	hypothetical protein	A0A2R2ZGK7	Clostridioides_phage	4.3e-28	98.6
AWH83489.1\|103698_103830_-	hypothetical protein	A0A2R2ZGL5	Clostridioides_phage	6.7e-16	100.0
AWH83490.1\|104012_105857_-	hypothetical protein	A0A2R2ZGM4	Clostridioides_phage	0.0e+00	100.0
AWH83491.1\|105901_107014_-\|integrase	site-specific integrase	A0A2R2ZGM9	Clostridioides_phage	3.9e-205	100.0
AWH83492.1\|107464_108307_+	hypothetical protein	A0A2R2ZGM6	Clostridioides_phage	2.5e-159	100.0
AWH83493.1\|108309_109620_+\|transposase	ISL3 family transposase	A0A2R2ZGN7	Clostridioides_phage	1.9e-235	99.8
AWH83494.1\|109707_110367_-	hypothetical protein	A0A0A8WHZ4	Clostridium_phage	8.5e-123	99.5
AWH83495.1\|110375_110906_-	deoxyuridine 5'-triphosphate nucleotidohydrolase	A0A0A8WIQ1	Clostridium_phage	9.6e-69	75.3
AWH83496.1\|110929_111424_-	crossover junction endodeoxyribonuclease RuvC	A0A0A8WF06	Clostridium_phage	8.9e-85	98.8
AWH83497.1\|111414_111987_-	guanylate kinase	A0A2R2ZGN1	Clostridioides_phage	4.0e-105	97.9
AWH83498.1\|111986_112370_-	hypothetical protein	A0A0A8WEF9	Clostridium_phage	3.1e-69	98.4
AWH83499.1\|112402_113233_-	SsmT	A0A0A8WHZ5	Clostridium_phage	1.5e-161	99.3
AWH83500.1\|113266_114418_-	site-specific DNA-methyltransferase	A0A0A8WIQ4	Clostridium_phage	4.3e-223	99.2
AWH83501.1\|114439_115240_-	hypothetical protein	A0A2R2ZH44	Clostridioides_phage	8.6e-146	95.5
AWH83502.1\|115313_115523_-	hypothetical protein	A0A0A8WJG7	Clostridium_phage	3.1e-31	98.6
AWH83503.1\|115533_115791_-	hypothetical protein	A0A0A8WEG3	Clostridium_phage	4.6e-32	97.6
AWH83504.1\|115774_116029_-	hypothetical protein	A0A0A8WHZ8	Clostridium_phage	8.5e-39	100.0
AWH83505.1\|116025_116553_-\|protease	spore protease YyaC	A0A0A8WIQ6	Clostridium_phage	1.8e-83	94.9
116374:116393	attR	NA	NA	NA	NA
AWH83506.1\|116580_117024_-	hypothetical protein	A0A0A8WJG9	Clostridium_phage	1.2e-80	98.6
AWH83507.1\|117047_117854_-	hypothetical protein	A0A2R2ZGN0	Clostridioides_phage	7.1e-140	93.2
AWH83508.1\|117874_118405_-	hypothetical protein	A0A2R2ZGN3	Clostridioides_phage	2.9e-97	98.9
AWH83509.1\|118509_119571_-	hypothetical protein	A0A0A8WIQ8	Clostridium_phage	1.4e-204	99.7
AWH83510.1\|119580_121107_-	hypothetical protein	A0A0A8WF16	Clostridium_phage	9.3e-266	100.0
AWH83511.1\|121147_121699_-	hypothetical protein	A0A0A8WJH2	Clostridium_phage	5.3e-102	100.0
AWH83512.1\|121759_122317_-	recombination protein	A0A0A8WEG9	Clostridium_phage	2.0e-96	100.0
AWH83513.1\|122356_123250_-	hypothetical protein	A0A0A8WI02	Clostridium_phage	3.7e-137	100.0
AWH83514.1\|123295_123964_-	hypothetical protein	A0A2R2ZGQ4	Clostridioides_phage	4.6e-108	86.5
AWH83515.1\|123975_124536_-	hypothetical protein	A0A2R2ZGQ3	Clostridioides_phage	2.0e-101	97.8
AWH83516.1\|124659_124968_-	hypothetical protein	A0A0A8WF25	Clostridium_phage	1.3e-49	99.0
AWH83517.1\|124967_125219_-	hypothetical protein	A0A0A8WJH6	Clostridium_phage	2.0e-24	95.1
AWH83518.1\|125322_128394_-	PHP domain-containing protein	A0A0A8WEH6	Clostridium_phage	0.0e+00	98.7
AWH83519.1\|128422_128668_-	hypothetical protein	A0A0A8WI06	Clostridium_phage	2.3e-41	98.8
AWH83520.1\|128708_130274_-	DNA cytosine methyltransferase	A0A0E3DF50	Bacillus_phage	1.8e-09	56.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP029154

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP029154_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029154_1

32087-32179

Orphan

Consensus_repeat	Method
GTTGGCGCTGTGCGTTAGCACTTTAAGCAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029154_1

>merge|CP029154|1|32087-32179|CRISPRCasFinder
GTTGGCGCTGTGCGTTAGCACTTTAAGCAACAGAATAAACTGAACGCATGTGAAGTTTGTTTGTTGGCGCTGTGCGTTAGCACTTTAAGCAAC

>CP029154|1|1|32087-32179|CRISPRCasFinder
GTTGGCGCTGTGCGTTAGCACTTTAAGCAAC	AGAATAAACTGAACGCATGTGAAGTTTGTTT
GTTGGCGCTGTGCGTTAGCACTTTAAGCAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP029154.1\|AWH79557.1\|24776_25232_+\|nucleoside-deaminase	unknown	unknown	gnl\|CDD\|223663
CP029154.1\|AWH79556.1\|23184_24456_+\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
CP029154.1\|AWH79571.1\|52223_53294_+\|dna-integrity-scanning-protein-disa	unknown	unknown	gnl\|CDD\|237395
CP029154.1\|AWH79572.1\|53382_54477_+\|PIN/TRAM-domain-containing-protein	unknown	unknown	gnl\|CDD\|227292
CP029154.1\|AWH79561.1\|28502_28724_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH79566.1\|46227_46692_+\|CtsR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226869
CP029154.1\|AWH79559.1\|27398_27749_+\|nucleoid-associated-protein,-YbaB/EbfC-family	unknown	unknown	gnl\|CDD\|234669
CP029154.1\|AWH79565.1\|43842_45771_+\|elongation-factor-G	unknown	unknown	gnl\|CDD\|237186
CP029154.1\|AWH79560.1\|27761_28361_+\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
CP029154.1\|AWH79553.1\|9856_10630_+\|SigB/SigF/SigG-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274373
CP029154.1\|AWH79564.1\|40169_43601_+\|pyruvate-carboxylase	unknown	unknown	gnl\|CDD\|237263
CP029154.1\|AWH79568.1\|47208_48234_+\|protein-arginine-kinase	unknown	unknown	gnl\|CDD\|234894
CP029154.1\|AWH79569.1\|48220_50668_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|223616
CP029154.1\|AWH79570.1\|50847_52221_+\|DNA-repair-protein-RadA	unknown	unknown	gnl\|CDD\|236994
CP029154.1\|AWH79554.1\|21323_21833_+\|transcription-repressor-NadR	unknown	unknown	gnl\|CDD\|224740
CP029154.1\|AWH79562.1\|28794_30000_-\|glycosyl-transferase	unknown	unknown	gnl\|CDD\|340861
CP029154.1\|AWH79567.1\|46698_47193_+\|DNA-methylase	unknown	unknown	gnl\|CDD\|226397
CP029154.1\|AWH79555.1\|21844_22726_+\|mechanosensitive-ion-channel-protein	unknown	unknown	gnl\|CDD\|182386
CP029154.1\|AWH79563.1\|39447_39861_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH79558.1\|25702_27340_+\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|235505

Protein	Function_ID	Function_description	E-value
CP029154.1\|AWH79557.1\|24776_25232_+\|nucleoside-deaminase	gnl\|CDD\|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	7.52683e-52
CP029154.1\|AWH79556.1\|23184_24456_+\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
CP029154.1\|AWH79571.1\|52223_53294_+\|dna-integrity-scanning-protein-disa	gnl\|CDD\|237395	PRK13482, PRK13482, DNA integrity scanning protein DisA; Provisional.	0
CP029154.1\|AWH79572.1\|53382_54477_+\|PIN/TRAM-domain-containing-protein	gnl\|CDD\|227292	COG4956, COG4956, Integral membrane protein (PIN domain superfamily) [General function prediction only].	6.40242e-141
CP029154.1\|AWH79566.1\|46227_46692_+\|CtsR-family-transcriptional-regulator	gnl\|CDD\|226869	COG4463, CtsR, Transcriptional repressor of class III stress genes [Transcription].	4.90874e-42
CP029154.1\|AWH79559.1\|27398_27749_+\|nucleoid-associated-protein,-YbaB/EbfC-family	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	1.04649e-45
CP029154.1\|AWH79565.1\|43842_45771_+\|elongation-factor-G	gnl\|CDD\|237186	PRK12740, PRK12740, elongation factor G-like protein EF-G2.	0
CP029154.1\|AWH79560.1\|27761_28361_+\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	6.04881e-129
CP029154.1\|AWH79553.1\|9856_10630_+\|SigB/SigF/SigG-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274373	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily. This group of similar sigma-70 factors includes clades found in Bacilli (including the sporulation factors SigF:TIGR02885 and SigG:TIGR02850 as well as SigB:TIGR02941), and the high GC gram positive bacteria (Actinobacteria) where a variable number of them are found depending on the lineage.	6.4918e-87
CP029154.1\|AWH79562.1\|28794_30000_-\|glycosyl-transferase	gnl\|CDD\|340861	cd17507, GT28_Beta-DGS-like, beta-diglucosyldiacylglycerol synthase and similar proteins. beta-diglucosyldiacylglycerol synthase (processive diacylglycerol beta-glucosyltransferase EC 2.4.1.315) is involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. This family of glycosyltransferases also contains plant major galactolipid synthase (chloroplastic monogalactosyldiacylglycerol synthase 1 EC 2.4.1.46). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	1.60211e-148
CP029154.1\|AWH79568.1\|47208_48234_+\|protein-arginine-kinase	gnl\|CDD\|234894	PRK01059, PRK01059, ATP:guanido phosphotransferase; Provisional.	1.50225e-165
CP029154.1\|AWH79569.1\|48220_50668_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl\|CDD\|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	0
CP029154.1\|AWH79570.1\|50847_52221_+\|DNA-repair-protein-RadA	gnl\|CDD\|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0
CP029154.1\|AWH79554.1\|21323_21833_+\|transcription-repressor-NadR	gnl\|CDD\|224740	COG1827, COG1827, Predicted small molecule binding protein (contains 3H domain) [General function prediction only].	8.64345e-43
CP029154.1\|AWH79564.1\|40169_43601_+\|pyruvate-carboxylase	gnl\|CDD\|237263	PRK12999, PRK12999, pyruvate carboxylase; Reviewed.	0
CP029154.1\|AWH79567.1\|46698_47193_+\|DNA-methylase	gnl\|CDD\|226397	COG3880, COG3880, Modulator of heat shock repressor CtsR, McsA [Signal transduction mechanisms].	2.05547e-43
CP029154.1\|AWH79555.1\|21844_22726_+\|mechanosensitive-ion-channel-protein	gnl\|CDD\|182386	PRK10334, PRK10334, small-conductance mechanosensitive channel MscS.	1.72542e-62
CP029154.1\|AWH79558.1\|25702_27340_+\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|235505	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated.	0

>CP029154.1|AWH79562.1|28794_30000_-|glycosyl-transferase
MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDSLKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFKKLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLISVLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKDIVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIEKKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPGQEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIANLILNIISG
>CP029154.1|AWH79561.1|28502_28724_+|hypothetical-protein
MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTKKNVRNKNAEFRNNYKNYQYDYEEDFYEPI
>CP029154.1|AWH79560.1|27761_28361_+|recombination-protein-RecR
MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEALSKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFKGQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARLVKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI
>CP029154.1|AWH79559.1|27398_27749_+|nucleoid-associated-protein,-YbaB/EbfC-family
MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVEASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQMSKVTGGMNIPGLF
>CP029154.1|AWH79558.1|25702_27340_+|DNA-polymerase-III-subunit-gamma/tau
MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCGTRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDDIRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHKIPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALSILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKDIRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILSITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGNNKEKKYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEVKSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKDINLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK
>CP029154.1|AWH79557.1|24776_25232_+|nucleoside-deaminase
MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTETLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTRHVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD
>CP029154.1|AWH79556.1|23184_24456_+|serine--tRNA-ligase
MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQEVEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLMRIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITGSRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDMFKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLVRQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFKYDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRCLAAILENYQQADGSVVVPEELRPYMGVDVIR
>CP029154.1|AWH79555.1|21844_22726_+|mechanosensitive-ion-channel-protein
MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVIGIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVAVLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLKTPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKRILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVPSSLLFNNTGNLNTMDKR
>CP029154.1|AWH79554.1|21323_21833_+|transcription-repressor-NadR
MNSNERRSKLIDILKESKHPVKGGILAELLNVSRQVIVQDIALIRARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNHPTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVKELKDNGILS
>CP029154.1|AWH79553.1|9856_10630_+|SigB/SigF/SigG-family-RNA-polymerase-sigma-factor
MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARLLAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKVWTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQPMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRFFFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL
>CP029154.1|AWH79563.1|39447_39861_+|hypothetical-protein
MYIVIGNEIVDSEELKIIIDKNSKFKVEKDLSKSTKREDVIAYQLSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKLDEVDGIVKIILVVAYADLGHLKLSDVVKRLSRQVD
>CP029154.1|AWH79564.1|40169_43601_+|pyruvate-carboxylase
MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLFRTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEENGITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVMIKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQILGDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAGTLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKSQDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPHYDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTKFIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEGSKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQKDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPDNVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKTKTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTHDTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGYDELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVKEKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCKGMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNVISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEIGEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKIMVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK
>CP029154.1|AWH79565.1|43842_45771_+|elongation-factor-G
MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDKVNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGTEKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLHNVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGIQRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMSYIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLKTGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRNTETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQSGGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVTNIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGDVMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERYGEVPSQFAEKIIGLATAK
>CP029154.1|AWH79566.1|46227_46692_+|CtsR-family-transcriptional-regulator
MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVLTTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEGLKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE
>CP029154.1|AWH79567.1|46698_47193_+|DNA-methylase
MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLDMPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPMLQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLKGSID
>CP029154.1|AWH79568.1|47208_48234_+|protein-arginine-kinase
MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFINSNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEEDHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASVMMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNIIENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNIKMGIEMNYIDKLDLKAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRGGMNCELQ
>CP029154.1|AWH79569.1|48220_50668_+|ATP-dependent-Clp-protease-ATP-binding-subunit
MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEGIAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNYIGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQNQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVGKTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKNGNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDSALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRYLPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRDEQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLEEILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEVQFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEIEKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAKGDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKGSNVVAKVKDEKIVFETK
>CP029154.1|AWH79570.1|50847_52221_+|DNA-repair-protein-RadA
MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKKEVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKSTLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYLESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKEGSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDNPSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGMLLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTGEVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEMWPVDNLRQAINIVLGRNQ
>CP029154.1|AWH79571.1|52223_53294_+|dna-integrity-scanning-protein-disa
MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATNEDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSETGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLEKYKTVLDQAITNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLVSMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSGFSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEIRATYIKNGLIKMKQLVLLDRHI
>CP029154.1|AWH79572.1|53382_54477_+|PIN/TRAM-domain-containing-protein
MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAAVVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLLSGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKENKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKRVRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNKVAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGGRKYMNETIKVLVTSVLQTPAGRMIFAKPKN

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Crispr_ID: CP029154_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029154_2

641941-642065

Orphan

Consensus_repeat	Method
TGATGGTTGATAAGAATAGTAAGAAAAAAATAGATAATTAAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029154_2

>merge|CP029154|2|641941-642065|CRISPRCasFinder
TGATGGTTGATAAGAATAGTAAGAAAAAAATAGATAATTAAAGAGTTAGAGTGAAAGAGTAATCGTAAAATAAATATATGGATGATGGTTGATAAGAATAGTAAGAAAAAATAGATAATTAAAGG

>CP029154|2|2|641941-642065|CRISPRCasFinder
TGATGGTTGATAAGAATAGTAAGAAAAAAATAGATAATTAAAG	AGTTAGAGTGAAAGAGTAATCGTAAAATAAATATATGGA
TGATGGTTGATAAGAATAGTAAGAAAAAATAGATAATTAAAGG

Protein	Signature genes	Signature genes Name	Protein_function
CP029154.1\|AWH80064.1\|636643_637255_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH80070.1\|643403_644675_-\|peptidoglycan-binding-protein	unknown	unknown	gnl\|CDD\|366659
CP029154.1\|AWH80066.1\|638685_639045_+\|BlaI/MecI/CopY-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367747
CP029154.1\|AWH80069.1\|642276_642933_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH80076.1\|649201_650869_+\|nucleoside-kinase	unknown	unknown	gnl\|CDD\|238986
CP029154.1\|AWH80071.1\|644919_645636_+\|protease-PrsW	unknown	unknown	gnl\|CDD\|379143
CP029154.1\|AWH80073.1\|647124_647661_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
CP029154.1\|AWH80067.1\|639055_640438_+\|penicillin-binding-protein	unknown	unknown	gnl\|CDD\|320700
CP029154.1\|AWH80068.1\|640653_641064_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366959
CP029154.1\|AWH80074.1\|647826_648363_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
CP029154.1\|AWH80060.1\|633088_633892_+\|protein-glutamate-O-methyltransferase-CheR	unknown	unknown	gnl\|CDD\|224271
CP029154.1\|AWH80059.1\|632612_633053_+\|chemotaxis-protein	unknown	unknown	gnl\|CDD\|238374
CP029154.1\|AWH80063.1\|635563_636553_+\|ornithine-cyclodeaminase-family-protein	unknown	unknown	gnl\|CDD\|236313
CP029154.1\|AWH80077.1\|651840_652770_+\|glutaminase	unknown	unknown	gnl\|CDD\|274797
CP029154.1\|AWH83264.1\|651043_651391_-\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH80075.1\|648372_649128_+\|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl\|CDD\|366542
CP029154.1\|AWH80072.1\|645714_647025_+\|methylase	unknown	unknown	gnl\|CDD\|183387
CP029154.1\|AWH80061.1\|633931_634528_+\|chemotaxis-protein-CheB	unknown	unknown	gnl\|CDD\|319751
CP029154.1\|AWH80062.1\|634633_635497_+\|DUF3298/DUF4163-domain-containing-protein	unknown	unknown	gnl\|CDD\|379356
CP029154.1\|AWH80065.1\|637701_638481_+\|DUF975-domain-containing-protein	unknown	unknown	gnl\|CDD\|283754

Protein	Function_ID	Function_description	E-value
CP029154.1\|AWH80071.1\|644919_645636_+\|protease-PrsW	gnl\|CDD\|379143	pfam13367, PrsW-protease, Protease prsW family. This is a family of putative peptidases, possibly belonging to the MEROPS M79 family. PrsW, appears to be a member of a widespread family of membrane proteins that includes at least one previously known protease. PrsW appears to be responsible for Site-1 cleavage of the RsiW anti-sigma factor, the cognate anti-sigma factor, and it senses antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress, The three acidic residues, E75, E76 and E95 in Aflv_1074, appear to be crucial since their mutation to alanine renders the protein inactive. Based on predictions of the bioinformatics programme TMHMM it is likely that these residues are located on the extracytoplasmic face of PrsW placing them in a position to act as a sensor for cell envelope stress.	6.62657e-44
CP029154.1\|AWH80070.1\|643403_644675_-\|peptidoglycan-binding-protein	gnl\|CDD\|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	1.30519e-11
CP029154.1\|AWH80066.1\|638685_639045_+\|BlaI/MecI/CopY-family-transcriptional-regulator	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	2.78956e-27
CP029154.1\|AWH80076.1\|649201_650869_+\|nucleoside-kinase	gnl\|CDD\|238986	cd02028, UMPK_like, Uridine monophosphate kinase_like (UMPK_like) is a family of proteins highly similar to the uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK).	1.5568e-65
CP029154.1\|AWH80073.1\|647124_647661_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	4.81089e-46
CP029154.1\|AWH80067.1\|639055_640438_+\|penicillin-binding-protein	gnl\|CDD\|320700	cd07341, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	4.08749e-43
CP029154.1\|AWH80068.1\|640653_641064_+\|hypothetical-protein	gnl\|CDD\|366959	pfam02181, FH2, Formin Homology 2 Domain.	0.00437435
CP029154.1\|AWH80074.1\|647826_648363_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	7.44134e-44
CP029154.1\|AWH80060.1\|633088_633892_+\|protein-glutamate-O-methyltransferase-CheR	gnl\|CDD\|224271	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms].	1.30894e-87
CP029154.1\|AWH80059.1\|632612_633053_+\|chemotaxis-protein	gnl\|CDD\|238374	cd00732, CheW, CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together with CheA and the methyl-accepting chemotaxis proteins (MCPs), which are involved in response modulation.	7.00197e-30
CP029154.1\|AWH80063.1\|635563_636553_+\|ornithine-cyclodeaminase-family-protein	gnl\|CDD\|236313	PRK08618, PRK08618, ornithine cyclodeaminase family protein.	0
CP029154.1\|AWH80077.1\|651840_652770_+\|glutaminase	gnl\|CDD\|274797	TIGR03814, Glutaminase_1, glutaminase A. This family describes the enzyme glutaminase, from a larger family that includes serine-dependent beta-lactamases and penicillin-binding proteins. Many bacteria have two isozymes. This model is based on selected known glutaminases and their homologs within prokaryotes, with the exclusion of highly-derived (long branch) and architecturally varied homologs, so as to achieve conservative assignments. A sharp drop in scores occurs below 250, and cutoffs are set accordingly. The enzyme converts glutamine to glutamate, with the release of ammonia. Members tend to be described as glutaminase A (glsA), where B (glsB) is unknown and may not be homologous (as in Rhizobium etli). Some species have two isozymes that may both be designated A (GlsA1 and GlsA2). [Energy metabolism, Amino acids and amines].	8.90258e-178
CP029154.1\|AWH80075.1\|648372_649128_+\|sugar-phosphate-isomerase/epimerase	gnl\|CDD\|366542	pfam01261, AP_endonuc_2, Xylose isomerase-like TIM barrel. This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.	3.30793e-12
CP029154.1\|AWH80072.1\|645714_647025_+\|methylase	gnl\|CDD\|183387	PRK11933, yebU, rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed.	1.13717e-75
CP029154.1\|AWH80061.1\|633931_634528_+\|chemotaxis-protein-CheB	gnl\|CDD\|319751	cd16432, CheB_Rec, Chemotaxis response regulator protein-glutamate methylesterase, CheB, with N-terminal REC domain. This family contains the methylesterase CheB (EC 3.1.1.61; also known as CheB methylesterase, chemotaxis-specific methylesterase, methyl-accepting chemotaxis protein methyl-esterase, or protein methyl-esterase) domain with a REC domain at the N-terminus. CheB is a phosphorylation-activated response regulator involved in reversible modification of bacterial chemotaxis receptors. Signaling output of the chemotaxis receptors is modulated by CheB and methyltransferase CheR by controlling the level of receptor methylation. The N-terminal regulatory (REC) domain blocks the active site of the C-terminal domain until it is phosphorylated. Reversible methylation of transmembrane chemoreceptors plays an important role in ligand-dependent signaling and cellular adaptation in bacterial chemotaxis. Phosphorylated CheB catalyzes deamidation of specific glutamine residues in the cytoplasmic region of the chemoreceptors and demethylation of specific methyl glutamate residues introduced into the chemoreceptors by CheR.	1.45154e-89
CP029154.1\|AWH80062.1\|634633_635497_+\|DUF3298/DUF4163-domain-containing-protein	gnl\|CDD\|379356	pfam13739, DUF4163, Domain of unknown function (DUF4163). The structure of this domain is and alpha-beta-two layer sandwich, identified from a Fervidobacterium nodosum Rt17-B1 like protein. The function is not known except that it is found in association with Heat-shock cognate 70kd protein 44kd ATPase, pfam11738.	2.94213e-18
CP029154.1\|AWH80065.1\|637701_638481_+\|DUF975-domain-containing-protein	gnl\|CDD\|283754	pfam06161, DUF975, Protein of unknown function (DUF975). Family of uncharacterized bacterial proteins.	3.75458e-25

>CP029154.1|AWH80068.1|640653_641064_+|hypothetical-protein
MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKLESLIKSGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQELEKIKTEGLKIMKPITIKNEDGSQISIAYNYAAID
>CP029154.1|AWH80067.1|639055_640438_+|penicillin-binding-protein
MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLFKLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSAGKNNSDEFEIMSSIENIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRRFIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFMLVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPFSMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESFGLTKNEQSDKIGFSISSKSTDLYSPKLESDILVSKAKSDGETHFSTAKVSVIEFREHEESSTSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIERSNYNDNRFVISRKGNLLAVNKEQYRTWIE
>CP029154.1|AWH80066.1|638685_639045_+|BlaI/MecI/CopY-family-transcriptional-regulator
MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYTVIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKENLSNDEITKLKQIVEKLK
>CP029154.1|AWH80065.1|637701_638481_+|DUF975-domain-containing-protein
MVSRQELKRVSKAQLSGNWGICAISMAVYIALLVLISIVGLPFEPLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVYIYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYILLLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFILNFSFIGWYILSIATLGIGLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY
>CP029154.1|AWH80064.1|636643_637255_+|hypothetical-protein
MKMVKKLILSSIMALVLVLTIGCSNAEEKVKSNFEANLAALEMYKYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVEKTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTKMIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI
>CP029154.1|AWH80063.1|635563_636553_+|ornithine-cyclodeaminase-family-protein
MLLLKKDDIEKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISVPSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLDGTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSRNKESREKFAEEMNLKLSKYNTKIVAVESSDKAIDNADVIVLATPSKQPVFNGNLVKKGALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSGDLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGMDWKW
>CP029154.1|AWH80062.1|634633_635497_+|DUF3298/DUF4163-domain-containing-protein
MKFFKVDTKARVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASINLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSNKIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSIKVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYTEVIDEEIKRQIAELEKKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSMLKPEYVDLFDLK
>CP029154.1|AWH80061.1|633931_634528_+|chemotaxis-protein-CheB
MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAIFTYMYAQRLDKQCIMNVRETKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGERISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGANGLLKMKENGSFTIGQDENSCIVYGMPMIAFDRGSVMLQLPLGEISNCLIRHINILKQKD
>CP029154.1|AWH80060.1|633088_633892_+|protein-glutamate-O-methyltransferase-CheR
MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKLSSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIRNINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIESNVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMIYFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR
>CP029154.1|AWH80059.1|632612_633053_+|chemotaxis-protein
MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPTYISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVITIENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSM
>CP029154.1|AWH80069.1|642276_642933_+|hypothetical-protein
MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKFAVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGMLPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIVDWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
>CP029154.1|AWH80070.1|643403_644675_-|peptidoglycan-binding-protein
MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLRSNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEARQGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNPVVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTLNRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQPLLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVSFPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGLPQSGVVDFKTWYEISRVYVATTRIASLNPLI
>CP029154.1|AWH80071.1|644919_645636_+|protease-PrsW
MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFLSVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLDGIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKYKFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLEKYMNHSKKVFFGNLRKKKKK
>CP029154.1|AWH80072.1|645714_647025_+|methylase
MTELPKKFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDKKRLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIKEGEKILDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITNTDSNSLRKTFNGYFNKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDGYKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAKIKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPEIYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLKGDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF
>CP029154.1|AWH80073.1|647124_647661_+|signal-peptidase-I
MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTLVERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSKVYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTILGKVLVRLYPFSKIGTID
>CP029154.1|AWH80074.1|647826_648363_+|signal-peptidase-I
MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTLKSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSKVYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENIKGKVILRVFPFTDIGIFE
>CP029154.1|AWH80075.1|648372_649128_+|sugar-phosphate-isomerase/epimerase
MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKYKERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIESELKGFDIRYFNLHLGYVMTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRIKNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIKEVLTLDAEYLVLEINYEDIEDTISKLNNIVGEG
>CP029154.1|AWH80076.1|649201_650869_+|nucleoside-kinase
MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLAVVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEHSLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMYEKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEEDKTLPMKFIPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKKLSQIADMIKDGNKRVILIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKHTPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDSNQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRDYNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEEIKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD
>CP029154.1|AWH83264.1|651043_651391_-|hypothetical-protein
MTSKLLTKHLLLFYSFTLLLFYSFTLLLFYSFTLLLFYSFTLLLFYSFTLLLFYSFTLLLFYSFTLLLFYSFTLLLFYSFTLLLFYSFTLLLFYSFTLLKNYHINEQNIKQKSKI
>CP029154.1|AWH80077.1|651840_652770_+|glutaminase
MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICIIDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMKLEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYKSEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGVDIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMGIGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF

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Crispr_ID: CP029154_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029154_6

1578987-1579214

Orphan

I-A

Consensus_repeat	Method
TGTTTTATATTAACTAAGTGGTATGTAAATAAAATAAAATT	PILER-CR
GTTTTATATTAACTAAGTGGTATGTAAATA	CRISPRCasFinder
GTTTTATATTAACTAAGTGGTATGTAAATA	CRT

3 spacers

The CRISPR arrays of CP029154_6

>merge|CP029154|6|1578987-1579214|PILER-CR,CRISPRCasFinder,CRT
GTTTTATATTAACTAAGTGGTATGTAAATAAAGTTAAATTTATTACATCTAATTCTGTCTCTTCATGTTTTATATTAACTAAGTGGTATGTAAATACAACAGCACCATAAAAAAAACCATTCCTAAAAAACTGTTTTATATTAACTAAGTGGTATGTAAATAGTATAATGTTGAAAAGTTAGAGAGTACAATCAAGAAGTTTTACATTAACTAAAATGTATAGAATAA

>CP029154|6|1|1578987-1579158|PILER-CR
GTTTTATATTAACTAAGTGGTATGTAAATAAAGTTAAATTT	ATTACATCTAATTCTGTCTCTTCAT
GTTTTATATTAACTAAGTGGTATGTAAATACAACAGCACCA	TAAAAAAAACCATTCCTAAAAAACTGTTTTATATT
AACTAAGTGGTATGTAAATAGTATAATGTT

>CP029154|6|6|1578987-1579214|CRISPRCasFinder
GTTTTATATTAACTAAGTGGTATGTAAATA	AAGTTAAATTTATTACATCTAATTCTGTCTCTTCAT
GTTTTATATTAACTAAGTGGTATGTAAATA	CAACAGCACCATAAAAAAAACCATTCCTAAAAAACT
GTTTTATATTAACTAAGTGGTATGTAAATA	GTATAATGTTGAAAAGTTAGAGAGTACAATCAAGAA
GTTTTACATTAACTAAAATGTATAGAATAA

>CP029154|6|1|1578987-1579214|CRT
GTTTTATATTAACTAAGTGGTATGTAAATA	AAGTTAAATTTATTACATCTAATTCTGTCTCTTCAT
GTTTTATATTAACTAAGTGGTATGTAAATA	CAACAGCACCATAAAAAAAACCATTCCTAAAAAACT
GTTTTATATTAACTAAGTGGTATGTAAATA	GTATAATGTTGAAAAGTTAGAGAGTACAATCAAGAA
GTTTTACATTAACTAAAATGTATAGAATAA

Protein	Signature genes	Signature genes Name	Protein_function
CP029154.1\|AWH80868.1\|1587457_1588132_-\|MgtC/SapB-family-protein	unknown	unknown	gnl\|CDD\|224204
CP029154.1\|AWH80870.1\|1588983_1589349_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
CP029154.1\|AWH83294.1\|1569645_1571076_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|226350
CP029154.1\|AWH80871.1\|1589579_1589714_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH80865.1\|1585401_1586211_+\|MerR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133378
CP029154.1\|AWH80867.1\|1586789_1586966_-\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH80859.1\|1575654_1577010_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240548
CP029154.1\|AWH80866.1\|1586363_1586603_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH80853.1\|1568861_1569446_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376406
CP029154.1\|AWH80858.1\|1574868_1575537_+\|diphthine--ammonia-ligase	unknown	unknown	gnl\|CDD\|238952
CP029154.1\|AWH80854.1\|1571403_1572348_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
CP029154.1\|AWH80861.1\|1578067_1578460_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|222853
CP029154.1\|AWH80862.1\|1579538_1581272_-\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
CP029154.1\|AWH80869.1\|1588351_1588906_-\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238496
CP029154.1\|AWH80863.1\|1581508_1582354_-\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
CP029154.1\|AWH80860.1\|1577513_1578008_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
CP029154.1\|AWH80856.1\|1573673_1574222_-\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH80864.1\|1582384_1584619_-\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
CP029154.1\|AWH80857.1\|1574373_1574802_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377396
CP029154.1\|AWH80855.1\|1572618_1573554_-\|TIGR01212-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|224163

Protein	Function_ID	Function_description	E-value
CP029154.1\|AWH80868.1\|1587457_1588132_-\|MgtC/SapB-family-protein	gnl\|CDD\|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	1.38574e-53
CP029154.1\|AWH80870.1\|1588983_1589349_-\|transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	4.48025e-25
CP029154.1\|AWH83294.1\|1569645_1571076_-\|PAS-domain-S-box-protein	gnl\|CDD\|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	4.90347e-136
CP029154.1\|AWH80865.1\|1585401_1586211_+\|MerR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	4.54289e-25
CP029154.1\|AWH80859.1\|1575654_1577010_-\|MATE-family-efflux-transporter	gnl\|CDD\|240548	cd13143, MATE_MepA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.	8.96466e-116
CP029154.1\|AWH80853.1\|1568861_1569446_-\|hypothetical-protein	gnl\|CDD\|376406	pfam00882, Zn_dep_PLPC, Zinc dependent phospholipase C.	2.48263e-20
CP029154.1\|AWH80858.1\|1574868_1575537_+\|diphthine--ammonia-ligase	gnl\|CDD\|238952	cd01994, Alpha_ANH_like_IV, This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily of proteins is predicted to bind ATP. This domainhas a strongly conserved motif SGGKD at the N terminus.	4.64591e-55
CP029154.1\|AWH80854.1\|1571403_1572348_+\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	9.34015e-27
CP029154.1\|AWH80861.1\|1578067_1578460_+\|hypothetical-protein	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.35865e-20
CP029154.1\|AWH80862.1\|1579538_1581272_-\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	2.53802e-46
CP029154.1\|AWH80869.1\|1588351_1588906_-\|cysteine-hydrolase	gnl\|CDD\|238496	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia.	1.86218e-57
CP029154.1\|AWH80860.1\|1577513_1578008_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.7703e-22
CP029154.1\|AWH80855.1\|1572618_1573554_-\|TIGR01212-family-radical-SAM-protein	gnl\|CDD\|224163	COG1242, COG1242, Predicted Fe-S oxidoreductase [General function prediction only].	4.25879e-178
CP029154.1\|AWH80864.1\|1582384_1584619_-\|GGDEF-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.74694e-91
CP029154.1\|AWH80857.1\|1574373_1574802_+\|hypothetical-protein	gnl\|CDD\|377396	pfam04657, DMT_YdcZ, Putative inner membrane exporter, YdcZ. DMT_YdcZ is a family of putative inner membrane exporters from both Gram-positive and Gram-negative bacteria.	2.2504e-17
CP029154.1\|AWH80863.1\|1581508_1582354_-\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	8.21235e-30

>CP029154.1|AWH80861.1|1578067_1578460_+|hypothetical-protein
MSYVIGKSNNNNLVFETFDKVIELYPNAKPVFHSDRGFQYTSKVFESKLLAQGMIQSMSRAGRCIDNAPMEGIWGILKVEMYYLRKFDTYEQLVKIIENYIYYYNNFRYQKRLNSMSPLEFRKYLSTEIA
>CP029154.1|AWH80860.1|1577513_1578008_-|site-specific-integrase
MLNSAKNQVGFIKSVLKESYRLKEISENICDFVTTLIKKNSSTSKFYTKQKAQLLLEKSKNIPIGIPIFLMLTLGLRFGEAVSLIWSDVDLDKKIIHVNQTLVYVDNKIIFKDPKTPKSKRKLFAPDELISLLEEEKFKQNKLKLQAILKNEFDLICLNKRFNP
>CP029154.1|AWH80859.1|1575654_1577010_-|MATE-family-efflux-transporter
MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSKGVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSIIILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKTDGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRKNSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSVINYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASIAVFAICMAFSEPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVISLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKVA
>CP029154.1|AWH80858.1|1574868_1575537_+|diphthine--ammonia-ligase
MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTISEEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAYGDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGEEFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGYLEIK
>CP029154.1|AWH80857.1|1574373_1574802_+|hypothetical-protein
MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVGAIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTLVSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN
>CP029154.1|AWH80856.1|1573673_1574222_-|hypothetical-protein
MYTNFNIDFNNFNKKENATKFMLMGVLLIILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVLIIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGICLILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY
>CP029154.1|AWH80855.1|1572618_1573554_-|TIGR01212-family-radical-SAM-protein
MDKFKYAFNNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDGSLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYAPLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHDSTSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVDGIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKRDELVGPIWSLKKWEILNQIDDTLKARNSYQSCKFV
>CP029154.1|AWH80854.1|1571403_1572348_+|EamA-family-transporter
MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLFFGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVLLYTSPLFLAIFSKVCYKENITRSKLFSLILCFIGAIMAVSGGRLDFQGLNAFGLFLGTLSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSCMLMLGIVPAALAYIFYATGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLFGVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI
>CP029154.1|AWH83294.1|1569645_1571076_-|PAS-domain-S-box-protein
MELDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKEDILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQAGKKLIITATPIFDENGNLEFTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPIINTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESELFGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGSLKNKKVDIRIISATNADLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKYYFNRYSSDFNLNKTISKEAMDAIANYGFPGNIRELQNIIQKILLTCTDNHITIDDLPNILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFGSSYKVAKHLEISQSKANRLIRKYTNT
>CP029154.1|AWH80853.1|1568861_1569446_-|hypothetical-protein
MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYKLKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSERWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKRTDYMNDLKFSAYTCNSVINYILDSILSNTIKSYNIANCG
>CP029154.1|AWH80862.1|1579538_1581272_-|GGDEF-domain-containing-protein
MSILLKKAPKLAKHIITSFYINRDIDEVLKYLCENVTWIGPGEQEFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGKYTVRTKENAQMILEVNQRCTFEIIEDRGKLLVKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTEVIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPDLPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDITQLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKNYSKLLEFGKIIHLDDIGKLLEVLHGNLRETIEIRQINSLTKNEWRWIRVQCSVIYDSDHNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIQEYLCSSDSKNNDALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSLTKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSKADGKNCYSTYE
>CP029154.1|AWH80863.1|1581508_1582354_-|GGDEF-domain-containing-protein
MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLGMTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYKVDVDEKPYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVLIDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKNYVYSQLETLRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKFDKNDY
>CP029154.1|AWH80864.1|1582384_1584619_-|GGDEF-domain-containing-protein
MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNREFMYQYIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKGIVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIRLPNEKEIYSNVTFSIGSTIWNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFNFKDNSFYNKLENDKEFLSEISYVLQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDLHLFEENCKNIRKWIDKNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYNVSTSNFSIEITENILIENTNTIIQQLTELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLSHNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPMECKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDFYNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEAAKHQKYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNVLSQFYSMLPVGIIRYDLFGDMIITYINEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFVYKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYIDINKIKNLTKI
>CP029154.1|AWH80865.1|1585401_1586211_+|MerR-family-DNA-binding-transcriptional-regulator
MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNISDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKENIIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRFNILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNSNNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK
>CP029154.1|AWH80866.1|1586363_1586603_+|hypothetical-protein
MKCSNCGSVNIEKGILTTGGIYAETIGLKYVGDGKLDKVINKTFPVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDEK
>CP029154.1|AWH80867.1|1586789_1586966_-|hypothetical-protein
MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVESCLHQVMVLVSKYN
>CP029154.1|AWH80868.1|1587457_1588132_-|MgtC/SapB-family-protein
MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIVALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLTTAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISNSTDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPLIETLEI
>CP029154.1|AWH80869.1|1588351_1588906_-|cysteine-hydrolase
MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNLPIIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIITKHTPDSFFETDLQSILEKKNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQVFMASLQNSFADVKNTDKFLSNYYK
>CP029154.1|AWH80870.1|1588983_1589349_-|transcriptional-regulator
MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNIYGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEYMLEHGQQEILDNKGICYNK
>CP029154.1|AWH80871.1|1589579_1589714_+|hypothetical-protein
MNISRKAMKIIELAQKIANKRGISVEEAWSEAVTEYKNKYEHIA

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Crispr_ID: CP029154_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029154_7

1688407-1689093

Orphan

I-A

Consensus_repeat	Method
GTTTTATATTAACTATATGGAATGTAAAT	CRISPRCasFinder
GTTTTATATTAACTATATGGAATGTAAAT	CRT

10 spacers

The CRISPR arrays of CP029154_7

>merge|CP029154|7|1688407-1689093|CRISPRCasFinder,CRT
GTTTTATATTAACTATATGGAATGTAAATTTGTCATAGTAGCGACTTATTACAAAGTATTTTTCTAGTTTTATATTAACTATATGGAATGTAAATTACATCCTCATTAATTTCTTTGCTATCCCAAACAGCAGTTTTATATTAACTATATGGAATGTAAATCTCTTACGCTTTTCAATCACTTTTTCCTTGCTAAAATTGTTTTATATTAACTATATGGAATGTAAATTTGGAAATAAGTATAAAGACAGTGATATGGAAATGGGTTTTATATTAACTATATGGAATGTAAATTATCCATTTCATATTTAGATAAAATCTCTTTAAATGCGTTTTATATTAACTATATGGAATGTAAATATGTTATTACATAAAAATTCTTCATCTATAACTTTAAGTTTTATATTAACTATATGGAATGTAAATAAAATAAGGGTTTAATTTCCCTGGTGTCGAGGAATAGTTTTATATTAACTATATGGAATGTAAATTTTAAATGAAACTCTTGAAATAGTTGACGTAGTAGCGTTTTATATTAACTATATGGAATGTAAATTATATATTAGATGTCAATGTCAAGGATACAAAATTTGTTTTATATTAACTATATGGAATTTAAATCCATCTTTTGTTGCTTTACATAAATTTATATTACTTACGTTTTATACTAACTATACAGAATATAATT

>CP029154|7|7|1688407-1689093|CRISPRCasFinder
GTTTTATATTAACTATATGGAATGTAAAT	TTGTCATAGTAGCGACTTATTACAAAGTATTTTTCTA
GTTTTATATTAACTATATGGAATGTAAAT	TACATCCTCATTAATTTCTTTGCTATCCCAAACAGCA
GTTTTATATTAACTATATGGAATGTAAAT	CTCTTACGCTTTTCAATCACTTTTTCCTTGCTAAAATT
GTTTTATATTAACTATATGGAATGTAAAT	TTGGAAATAAGTATAAAGACAGTGATATGGAAATGG
GTTTTATATTAACTATATGGAATGTAAAT	TATCCATTTCATATTTAGATAAAATCTCTTTAAATGC
GTTTTATATTAACTATATGGAATGTAAAT	ATGTTATTACATAAAAATTCTTCATCTATAACTTTAA
GTTTTATATTAACTATATGGAATGTAAAT	AAAATAAGGGTTTAATTTCCCTGGTGTCGAGGAATA
GTTTTATATTAACTATATGGAATGTAAAT	TTTAAATGAAACTCTTGAAATAGTTGACGTAGTAGC
GTTTTATATTAACTATATGGAATGTAAAT	TATATATTAGATGTCAATGTCAAGGATACAAAATTT
GTTTTATATTAACTATATGGAATTTAAAT	CCATCTTTTGTTGCTTTACATAAATTTATATTACTTAC
GTTTTATACTAACTATACAGAATATAATT

>CP029154|7|2|1688407-1689093|CRT
GTTTTATATTAACTATATGGAATGTAAAT	TTGTCATAGTAGCGACTTATTACAAAGTATTTTTCTA
GTTTTATATTAACTATATGGAATGTAAAT	TACATCCTCATTAATTTCTTTGCTATCCCAAACAGCA
GTTTTATATTAACTATATGGAATGTAAAT	CTCTTACGCTTTTCAATCACTTTTTCCTTGCTAAAATT
GTTTTATATTAACTATATGGAATGTAAAT	TTGGAAATAAGTATAAAGACAGTGATATGGAAATGG
GTTTTATATTAACTATATGGAATGTAAAT	TATCCATTTCATATTTAGATAAAATCTCTTTAAATGC
GTTTTATATTAACTATATGGAATGTAAAT	ATGTTATTACATAAAAATTCTTCATCTATAACTTTAA
GTTTTATATTAACTATATGGAATGTAAAT	AAAATAAGGGTTTAATTTCCCTGGTGTCGAGGAATA
GTTTTATATTAACTATATGGAATGTAAAT	TTTAAATGAAACTCTTGAAATAGTTGACGTAGTAGC
GTTTTATATTAACTATATGGAATGTAAAT	TATATATTAGATGTCAATGTCAAGGATACAAAATTT
GTTTTATATTAACTATATGGAATTTAAAT	CCATCTTTTGTTGCTTTACATAAATTTATATTACTTAC
GTTTTATACTAACTATACAGAATATAATT

Protein	Signature genes	Signature genes Name	Protein_function
CP029154.1\|AWH83299.1\|1698016_1698931_+\|EamA/RhaT-family-transporter	unknown	unknown	gnl\|CDD\|223769
CP029154.1\|AWH80959.1\|1693392_1693833_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|225064
CP029154.1\|AWH80964.1\|1699789_1700938_+\|DUF362-domain-containing-protein	unknown	unknown	gnl\|CDD\|224917
CP029154.1\|AWH80958.1\|1692838_1693066_-\|ferrous-iron-transport-protein-A	unknown	unknown	gnl\|CDD\|377199
CP029154.1\|AWH80955.1\|1685652_1687746_+\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
CP029154.1\|AWH80948.1\|1678561_1679131_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH80950.1\|1680334_1681249_-\|DUF2935-domain-containing-protein	unknown	unknown	gnl\|CDD\|378573
CP029154.1\|AWH80954.1\|1684076_1685000_-\|DUF2520-domain-containing-protein	unknown	unknown	gnl\|CDD\|378484
CP029154.1\|AWH80956.1\|1689741_1690560_+\|MerR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133409
CP029154.1\|AWH80947.1\|1677657_1678557_+\|4Fe-4S-binding-protein	unknown	unknown	gnl\|CDD\|274004
CP029154.1\|AWH80960.1\|1694005_1694974_+\|DUF2232-domain-containing-protein	unknown	unknown	unknown
CP029154.1\|AWH80952.1\|1682407_1683256_-\|pantoate--beta-alanine-ligase	unknown	unknown	gnl\|CDD\|234741
CP029154.1\|AWH80949.1\|1679297_1679945_-\|lactate-utilization-protein	unknown	unknown	gnl\|CDD\|376839
CP029154.1\|AWH80951.1\|1681814_1681997_-\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH80961.1\|1695450_1696659_+\|tyrosine--tRNA-ligase	unknown	unknown	gnl\|CDD\|237360
CP029154.1\|AWH80957.1\|1690692_1692813_-\|ferrous-iron-transport-protein-B	unknown	unknown	gnl\|CDD\|223447
CP029154.1\|AWH80953.1\|1683274_1684102_-\|3-methyl-2-oxobutanoate-hydroxymethyltransferase	unknown	unknown	gnl\|CDD\|234723
CP029154.1\|AWH80946.1\|1677497_1677647_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH80963.1\|1699153_1699699_+\|NADH-peroxidase	unknown	unknown	gnl\|CDD\|153105
CP029154.1\|AWH80962.1\|1696719_1697601_-\|polysaccharide-deacetylase	unknown	unknown	gnl\|CDD\|200569

Protein	Function_ID	Function_description	E-value
CP029154.1\|AWH83299.1\|1698016_1698931_+\|EamA/RhaT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	2.73137e-11
CP029154.1\|AWH80959.1\|1693392_1693833_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|225064	COG2153, ElaA, Predicted acyltransferase [General function prediction only].	2.14803e-35
CP029154.1\|AWH80964.1\|1699789_1700938_+\|DUF362-domain-containing-protein	gnl\|CDD\|224917	COG2006, COG2006, Uncharacterized conserved protein [Function unknown].	2.43048e-75
CP029154.1\|AWH80958.1\|1692838_1693066_-\|ferrous-iron-transport-protein-A	gnl\|CDD\|377199	pfam04023, FeoA, FeoA domain. This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.	1.57039e-13
CP029154.1\|AWH80950.1\|1680334_1681249_-\|DUF2935-domain-containing-protein	gnl\|CDD\|378573	pfam11155, DUF2935, Domain of unknown function (DUF2935). This family of proteins with unknown function appears to be restricted to Firmicutes. The structure of this protein has been solved and each domain is composed of four alpha helices. A metal cluster composed of iron and magnesium lies between the two domains.	1.40998e-33
CP029154.1\|AWH80955.1\|1685652_1687746_+\|GGDEF-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.23427e-88
CP029154.1\|AWH80954.1\|1684076_1685000_-\|DUF2520-domain-containing-protein	gnl\|CDD\|378484	pfam10728, DUF2520, Domain of unknown function (DUF2520). This presumed domain is found C-terminal to a Rossmann-like domain suggesting that these proteins are oxidoreductases.	6.31193e-41
CP029154.1\|AWH80956.1\|1689741_1690560_+\|MerR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|133409	cd04782, HTH_BltR, Helix-Turn-Helix DNA binding domain of the BltR transcription regulator. Helix-turn-helix (HTH) multidrug-efflux transporter transcription regulator, BltR (BmrR-like transporter) of Bacillus subtilis, and related proteins; N-terminal domain. Blt, like Bmr, is a membrane protein which causes the efflux of a variety of toxic substances and antibiotics. These regulators are comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the C-terminal domains are often unrelated and bind specific coactivator molecules. They share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	3.2764e-41
CP029154.1\|AWH80947.1\|1677657_1678557_+\|4Fe-4S-binding-protein	gnl\|CDD\|274004	TIGR02163, Ferredoxin-type_protein_NapH_homolog, ferredoxin-type protein, NapH/MauN family. Most members of this family are the NapH protein, found next to NapG,in operons that encode the periplasmic nitrate reductase. Some species with this reductase lack NapC but accomplish electron transfer to NapAB in some other manner, likely to involve NapH, NapG, and/or some other protein. A few members of this protein are designated MauN and are found in methylamine utilization operons in species that appear to lack a periplasmic nitrate reductase.	1.71934e-24
CP029154.1\|AWH80952.1\|1682407_1683256_-\|pantoate--beta-alanine-ligase	gnl\|CDD\|234741	PRK00380, panC, pantoate--beta-alanine ligase; Reviewed.	1.84322e-163
CP029154.1\|AWH80949.1\|1679297_1679945_-\|lactate-utilization-protein	gnl\|CDD\|376839	pfam02589, LUD_dom, LUD domain. This entry represents a domain found in lactate utilization proteins B (LutB) and C (LutC), as well as several uncharacterized proteins. LutB and LutC are encoded by th conserved LutABC operon in bacteria. They are involved in lactate utilization and is implicated in the oxidative conversion of L-lactate into pyruvate.	3.25008e-55
CP029154.1\|AWH80957.1\|1690692_1692813_-\|ferrous-iron-transport-protein-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	2.08419e-149
CP029154.1\|AWH80961.1\|1695450_1696659_+\|tyrosine--tRNA-ligase	gnl\|CDD\|237360	PRK13354, PRK13354, tyrosyl-tRNA synthetase; Provisional.	0
CP029154.1\|AWH80953.1\|1683274_1684102_-\|3-methyl-2-oxobutanoate-hydroxymethyltransferase	gnl\|CDD\|234723	PRK00311, panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase; Reviewed.	8.6689e-173
CP029154.1\|AWH80963.1\|1699153_1699699_+\|NADH-peroxidase	gnl\|CDD\|153105	cd01046, Rubrerythrin_like, rubrerythrin-like, diiron-binding domain. Rubrerythrin-like domain, similar to rubrerythrin, a nonheme iron binding domain found in many air-sensitive bacteria and archaea, and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system. The rubrerythrin protein has two domains, a binuclear metal center located within a four-helix bundle of the rubrerythrin domain, and a rubredoxin domain. The Rubrerythrin-like domains in this CD are singular domains (no C-terminus rubredoxin domain) and are phylogenetically distinct from rubrerythrin domains of rubrerythrin-rubredoxin proteins.	1.43332e-53
CP029154.1\|AWH80962.1\|1696719_1697601_-\|polysaccharide-deacetylase	gnl\|CDD\|200569	cd10944, CE4_SmPgdA_like, Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins. This family is represented by a putative polysaccharide deacetylase PgdA from the oral pathogen Streptococcus mutans (SmPgdA) and Bacillus subtilis YheN (BsYheN), which are members of the carbohydrate esterase 4 (CE4) superfamily. SmPgdA is an extracellular metal-dependent polysaccharide deacetylase with a typical CE4 fold, with metal bound to a His-His-Asp triad. It possesses de-N-acetylase activity toward a hexamer of chitooligosaccharide N-acetylglucosamine, but not shorter chitooligosaccharides or a synthetic peptidoglycan tetrasaccharide. SmPgdA plays a role in tuning cell surface properties and in interactions with (salivary) agglutinin, an essential component of the innate immune system, most likely through deacetylation of an as-yet-unidentified polysaccharide. SmPgdA shows significant homology to the catalytic domains of peptidoglycan deacetylases from Streptococcus pneumoniae (SpPgdA) and Listeria monocytogenes (LmPgdA), both of which are involved in the bacterial defense mechanism against human mucosal lysozyme. The Bacillus subtilis genome contains six polysaccharide deacetylase gene homologs: pdaA, pdaB (previously known as ybaN), yheN, yjeA, yxkH and ylxY. The biological function of BsYheN is still unknown. This family also includes many uncharacterized polysaccharide deacetylases mainly found in bacteria.	4.04909e-75

>CP029154.1|AWH80955.1|1685652_1687746_+|GGDEF-domain-containing-protein
MNKRNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPEGKVCWQVLYPEQNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRAFENYDSLITWQDGTVVHMHQSIDIANSTILNKAIKINEFNEISNTKEEKGVFNFSRDNFDYNSTLLYDALIRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLIYWEKIVHPEDWNRFYKSNTEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKIDSLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLNIDDFKNVNEMYDRDFGDNIIKTLAQSIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYDQIQNMIIHLQLWRKYGLNITISAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLKASINDDFRGFSLRFQPQVDTQSHKMIGVEVLLRWTNDKYKAISPLEFIPILEENDMINIVGAWVLRMALRTFRKWIDNYPFFKVSVNVSAVQILEDTFIKDIVKIIDDENFPYQNLVLELTESHTVQNLSILQSKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRVFVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGKPQTATEIFDLLKLDN
>CP029154.1|AWH80954.1|1684076_1685000_-|DUF2520-domain-containing-protein
MGSGKVGTSLANYFLSKGHCVSGFYGRNQLSLLESTNLTKTKIYSNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAGALIYSIHPIFAFSNKNTDIKKMKDICFSIEGDNEQDDLVVQNFIDGLGNHFFIRDKDTSSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEDESLKAISPLVKKNIENILDNGFTKALTGPVSRGDITPIKKHLSVLDKKDEEIYKILSLNLLKIIALGNDNSLKCTKNITIENAIENLISKSEKYKEIYKLLGGKNDEKYHTNF
>CP029154.1|AWH80953.1|1683274_1684102_-|3-methyl-2-oxobutanoate-hydroxymethyltransferase
MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGDSLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGRLIKEGGAHAVKLEGGSNVIKQIENIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSETAKQLIEDAKLIEKAGAFSIVLEGVPAKIAEMVTNSISIPTIGIGAGINCDGQILVYQDMLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVKTGAFPQEKHSFSINESELEKLY
>CP029154.1|AWH80952.1|1682407_1683256_-|pantoate--beta-alanine-ligase
MLVKEIKLLRNIIKDWRKDGYSIGLVTTMGFLHEGHQSLIKKAVKENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGNCTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMVKDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLNPKNIKELIIAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNFTFELNI
>CP029154.1|AWH80951.1|1681814_1681997_-|hypothetical-protein
MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDIVELCLHRVMILLCECGLA
>CP029154.1|AWH80950.1|1680334_1681249_-|DUF2935-domain-containing-protein
MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEADHYKKQFEDLLSYAVSASNGIIRPDILYSEELVTTLTSAAEQKTEEFTGIEINKNITTRELNLQSGVDPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPLLLEHIIHEANLYRSYVVDLENKIDIESKSAKEIELFWDHIMMEHALFMRGLLDPSEGELINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIKSIILPLLADHVLREANHYIRILESYKNM
>CP029154.1|AWH80949.1|1679297_1679945_-|lactate-utilization-protein
MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILDLIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFLMSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASPAVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL
>CP029154.1|AWH80948.1|1678561_1679131_+|hypothetical-protein
MKKFIICIIMFAISVLVLAGCSNDNKIKNEVDSMFNAIKTQDADTVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSILKKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKTGDNYVCKVNQESAMKLLNVITGGGIDYLADYNKDYYKQLDEEQKNYENKNS
>CP029154.1|AWH80947.1|1677657_1678557_+|4Fe-4S-binding-protein
MKLLSKINNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLCVPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPFGLVQDLLHKIPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAVVNVAGGGNPWFCKWICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGAIYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSSDCIRCGECIKVCPQNAITTTFSKDKKENNICAKKYRGI
>CP029154.1|AWH80946.1|1677497_1677647_+|hypothetical-protein
MSNFIKDNKKGISIIVISIIFIVLGTYRGETNTVLTKAIMICLECIGIG
>CP029154.1|AWH80956.1|1689741_1690560_+|MerR-family-DNA-binding-transcriptional-regulator
MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYYSVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKISSKMQNRISITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCKSKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIGKYEDSYKSYEKLKKYIYENEYKIIGNSYEESILDFFCESNEDNYMTEISIQVSR
>CP029154.1|AWH80957.1|1690692_1692813_-|ferrous-iron-transport-protein-B
MGLTHNSTKMSSLKDMFDIDNKEDQFIIALAGNPNTGKSTVFNHLTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFGNPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLGIPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIEDVVKSIQPELDNIIPGINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKINYDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYPSTLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLFTLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLIAILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVSYTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITWIFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLATGSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTALGFLMPTILVFVVCFLTTTVYNLFI
>CP029154.1|AWH80958.1|1692838_1693066_-|ferrous-iron-transport-protein-A
MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRKGPKNNLTVYKIRGSKIALRQEESSLILVSDI
>CP029154.1|AWH80959.1|1693392_1693833_-|GNAT-family-N-acetyltransferase
MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKSSYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIKVNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL
>CP029154.1|AWH80960.1|1694005_1694974_+|DUF2232-domain-containing-protein
MNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDFIVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINKPTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLMIALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRSLNQFLCCSKKAFYICVSYLAIFEVLKLWNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYARILFLIIILLLFFIFDVTVISLIIINAFLNKKIDIRLSQSNIVNKQINLLIEK
>CP029154.1|AWH80961.1|1695450_1696659_+|tyrosine--tRNA-ligase
MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGLDPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVLANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRYEGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIMMPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVNKIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAREAEERFKSVFQKGQIPEDIQTIQVEEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGKKKFVKIELVK
>CP029154.1|AWH80962.1|1696719_1697601_-|polysaccharide-deacetylase
MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLKAERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDDGPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDYKKLYPSRSLNLDTFVNELNKTDEAMKKALGKNFSSNVVRCPGGYMSWKNMEPLGNYLKEKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALDQIITYFKDNGYQFKILI
>CP029154.1|AWH83299.1|1698016_1698931_+|EamA/RhaT-family-transporter
MKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTPLQIITLRFFLAAIIMNLLFFKQIRANMSKKLLKAGGVLGIFLFLAFTVQTIGLMYTTPSKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFLTLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGYMGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLVIGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI
>CP029154.1|AWH80963.1|1699153_1699699_+|NADH-peroxidase
MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADEHRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEAEHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEMCKDEARHGKAFLGLLNRHFGK
>CP029154.1|AWH80964.1|1699789_1700938_+|DUF362-domain-containing-protein
MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIKPNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGIEEVANELSIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFTGGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGPSAGTTREIGVLLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILGEDIKDLIVKNYKVPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKEACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK

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Crispr_ID: CP029154_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029154_8

1779875-1780169

Orphan

NA:I-A

Consensus_repeat	Method
GTTTTAGATTAACTATATGGAATGTAAAT	PILER-CR
GTTTTAGATTAACTATATGGAATGTAAA	CRISPRCasFinder
GTTTTAGATTAACTATATGGAATGTAAAT	CRT

4 spacers

The CRISPR arrays of CP029154_8

>merge|CP029154|8|1779875-1780169|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGATTAACTATATGGAATGTAAATTTATCTGCGTCTTCTGAAATAGCATACTCTTCAAGAGGTTTTAGATTAACTATATGGAATGTAAATGTTGTAAGAAGTATCATTCTATTTTTTAATCTTTCTGTTTTAGATTAACTATATGGAATGTAAATCTTATTTATAGTTGGGAAAATGGTTATAAATGTGGTACGTTTTAGATTAACTATATGGAATGTAAAGCAACAAGAACAACAGTTGATTTTACCTTTTCTAGCCAACGTTTTATATTAACTATGTGGAGAAAAACT

>CP029154|8|2|1779875-1780101|PILER-CR
GTTTTAGATTAACTATATGGAATGTAAAT	TTATCTGCGTCTTCTGAAATAGCATACTCTTCAAGAG
GTTTTAGATTAACTATATGGAATGTAAAT	GTTGTAAGAAGTATCATTCTATTTTTTAATCTTTCT
GTTTTAGATTAACTATATGGAATGTAAAT	CTTATTTATAGTTGGGAAAATGGTTATAAATGTGGTAC
GTTTTAGATTAACTATATGGAATGTAAAG

>CP029154|8|8|1779875-1780168|CRISPRCasFinder
GTTTTAGATTAACTATATGGAATGTAAA	TTTATCTGCGTCTTCTGAAATAGCATACTCTTCAAGAG
GTTTTAGATTAACTATATGGAATGTAAA	TGTTGTAAGAAGTATCATTCTATTTTTTAATCTTTCT
GTTTTAGATTAACTATATGGAATGTAAA	TCTTATTTATAGTTGGGAAAATGGTTATAAATGTGGTAC
GTTTTAGATTAACTATATGGAATGTAAA	GCAACAAGAACAACAGTTGATTTTACCTTTTCTAGCCAAC
GTTTTATATTAACTATGTGGAGAAAAAC

>CP029154|8|3|1779875-1780169|CRT
GTTTTAGATTAACTATATGGAATGTAAAT	TTATCTGCGTCTTCTGAAATAGCATACTCTTCAAGAG
GTTTTAGATTAACTATATGGAATGTAAAT	GTTGTAAGAAGTATCATTCTATTTTTTAATCTTTCT
GTTTTAGATTAACTATATGGAATGTAAAT	CTTATTTATAGTTGGGAAAATGGTTATAAATGTGGTAC
GTTTTAGATTAACTATATGGAATGTAAAG	CAACAAGAACAACAGTTGATTTTACCTTTTCTAGCCAAC
GTTTTATATTAACTATGTGGAGAAAAACT

Protein	Signature genes	Signature genes Name	Protein_function
CP029154.1\|AWH81054.1\|1789497_1790544_+\|phage-tail-protein	unknown	unknown	gnl\|CDD\|377414
CP029154.1\|AWH81050.1\|1786140_1786842_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|236880
CP029154.1\|AWH81051.1\|1786834_1788799_+\|cell-wall-hydrolase	unknown	unknown	gnl\|CDD\|366353
CP029154.1\|AWH81049.1\|1783758_1786125_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131723
CP029154.1\|AWH81046.1\|1780286_1781039_+\|SHOCT-domain-containing-protein	unknown	unknown	gnl\|CDD\|378276
CP029154.1\|AWH81053.1\|1789077_1789497_+\|DUF2634-domain-containing-protein	unknown	unknown	gnl\|CDD\|378510
CP029154.1\|AWH81045.1\|1778977_1779139_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH81041.1\|1776327_1777638_+\|phage-tail-protein	unknown	unknown	gnl\|CDD\|377435
CP029154.1\|AWH81037.1\|1774955_1775303_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH81052.1\|1788812_1789073_+\|DUF2577-domain-containing-protein	unknown	unknown	gnl\|CDD\|378501
CP029154.1\|AWH81039.1\|1775720_1776158_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH81048.1\|1783104_1783683_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|376345
CP029154.1\|AWH83303.1\|1782071_1782467_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH81040.1\|1776150_1776327_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH81038.1\|1775302_1775728_+\|HK97-gp10-family-phage-protein	unknown	unknown	gnl\|CDD\|377415
CP029154.1\|AWH81043.1\|1778196_1778637_+\|phage-portal-protein	unknown	unknown	gnl\|CDD\|378084
CP029154.1\|AWH81047.1\|1781342_1781516_+\|CopG-family-transcriptional-regulator	unknown	unknown	unknown
CP029154.1\|AWH81042.1\|1777654_1778125_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378178
CP029154.1\|AWH81044.1\|1778636_1778831_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274054
CP029154.1\|AWH81036.1\|1774560_1774962_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP029154.1\|AWH81043.1\|1778196_1778637_+\|phage-portal-protein	gnl\|CDD\|378084	pfam08890, Phage_TAC_5, Phage XkdN-like tail assembly chaperone protein, TAC. This is a family of phage tail assembly chaperone proteins, TACs, from Gram-positive bacteriophages, in particular PBSX from Firmicutes.	8.20802e-57
CP029154.1\|AWH81051.1\|1786834_1788799_+\|cell-wall-hydrolase	gnl\|CDD\|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	3.03482e-33
CP029154.1\|AWH81049.1\|1783758_1786125_+\|hypothetical-protein	gnl\|CDD\|131723	TIGR02675, Mu-like_prophage_FluMu_protein_gp42, tape measure domain. Proteins containing this domain are strictly bacterial, including bacteriophage and prophage regions of bacterial genomes. Most members are 800 to 1800 amino acids long, making them among the longest predicted proteins of their respective phage genomes, where they are encoded in tail protein regions. This roughly 80-residue domain described here usually begins between residue 100 and 250. Many members are known or predicted to act as phage tail tape measure proteins, a minor tail component that regulates tail length.	8.61899e-15
CP029154.1\|AWH81046.1\|1780286_1781039_+\|SHOCT-domain-containing-protein	gnl\|CDD\|378276	pfam09851, SHOCT, Short C-terminal domain.	2.60785e-05
CP029154.1\|AWH81053.1\|1789077_1789497_+\|DUF2634-domain-containing-protein	gnl\|CDD\|378510	pfam10934, DUF2634, Protein of unknown function (DUF2634). Some members in this family of proteins are annotated as phage related, xkdS however currently there is no known function.	9.70876e-35
CP029154.1\|AWH81041.1\|1776327_1777638_+\|phage-tail-protein	gnl\|CDD\|377435	pfam04984, Phage_sheath_1, Phage tail sheath protein subtilisin-like domain. This entry represents the second domain in a variety of phage tail sheath proteins. According to ECOD this domain has a subtilisin-like structure.	2.35314e-37
CP029154.1\|AWH81052.1\|1788812_1789073_+\|DUF2577-domain-containing-protein	gnl\|CDD\|378501	pfam10844, DUF2577, Protein of unknown function (DUF2577). This family of proteins has no known function.	6.31686e-18
CP029154.1\|AWH81054.1\|1789497_1790544_+\|phage-tail-protein	gnl\|CDD\|377414	pfam04865, Baseplate_J, Baseplate J-like protein. The P2 bacteriophage J protein lies at the edge of the baseplate. This family also includes a number of bacterial homologs, which are thought to have been horizontally transferred.	1.80205e-50
CP029154.1\|AWH81048.1\|1783104_1783683_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|376345	pfam00542, Ribosomal_L12, Ribosomal protein L7/L12 C-terminal domain.	0.00094009
CP029154.1\|AWH81038.1\|1775302_1775728_+\|HK97-gp10-family-phage-protein	gnl\|CDD\|377415	pfam04883, HK97-gp10_like, Bacteriophage HK97-gp10, putative tail-component. This family of proteins is found in the caudovirales. It may be a tail component.	4.55311e-17
CP029154.1\|AWH81050.1\|1786140_1786842_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	1.75254e-11
CP029154.1\|AWH81042.1\|1777654_1778125_+\|hypothetical-protein	gnl\|CDD\|378178	pfam09393, DUF2001, Phage tail tube protein. This is a family of phage tail tube proteins including protein XkdM from phage-like element PBSX protein whose structure adopts a beta barrel flanked with alpha helical regions.	2.40208e-57
CP029154.1\|AWH81044.1\|1778636_1778831_+\|hypothetical-protein	gnl\|CDD\|274054	TIGR02247, Hypothetical_protein_K09H11.1, epoxide hydrolase N-terminal domain-like phosphatase. This model represents a small clade of sequences including C. elegans and mammalian sequences as well as a small number of bacteria. In eukaryotes, this domain exists as an N-terminal fusion to the soluble epoxide hydrolase enzyme and has recently been shown to be an active phosphatase, although the nature of the biological substrate is unclear. These appear to be members of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases by general homology and the conservation of all of the recognized catalytic motifs (although the first motif is unusual in the replacement of the more common aspartate with glycine...). The variable domain is found in between motifs 1 and 2, indicating membership in subfamily I and phylogeny and prediction of the alpha helical nature of the variable domain (by PSI-PRED) indicate membership in subfamily IA.	0.00562027

>CP029154.1|AWH81045.1|1778977_1779139_+|hypothetical-protein
MNNFLLNVIAGVIASLIFCLICKVFLKVKSHSTRGKSKSGWEFDFKIKFHKFK
>CP029154.1|AWH81044.1|1778636_1778831_+|hypothetical-protein
MRGGDFDASITHYCIQKLKWKPSEYMNLEVNERALAAASILIKIEDEEEAMKEAERERKRGRRR
>CP029154.1|AWH81043.1|1778196_1778637_+|phage-portal-protein
MSNLSAFLSQNAIKVDNVKYVASNRFLDKEGKPVEWELKVLSSEEDEALRRKCTKRVKVIGNNGKHTGQYTSEIDYNSYVAELCVASTVFPDLKDAELQNSYGVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTSFEDKVEEAKN
>CP029154.1|AWH81042.1|1777654_1778125_+|hypothetical-protein
MAQTINAKDTVSAKKAECFITIEGKRYNFMQAIDLEAKMEKNKSEVPILGRTTKGNKTTGSTNTGSATFHYNTSIFRELLYRYKETGEDIYFDIQVTNEDPTSAVGRQTVVLKDCNMDSGIITKFDADGEYLDEDMDFTFEDWELVEKFNLLAGME
>CP029154.1|AWH81041.1|1776327_1777638_+|phage-tail-protein
MALGGGTFVTQNKVLPGAYINFVSATRATSSLSDRGIVAIPLELDWGIDEEVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKASCTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITDLQDNDYITWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLFVEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVENKIKDKDLVESSLIYWAAGAIAGCDINKSNTNKKYDGEFDVDVNYTQIQLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTDDKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENIRAIEDFKTDDVSVELGNDKKTVIVSDAVKVINAMSKLYMTVSVS
>CP029154.1|AWH81040.1|1776150_1776327_+|hypothetical-protein
MSKTLSKEENYKFTKEQIVNSKRYVNRKDLLNAILKEDELYSFSEVEDMINNFMKGVS
>CP029154.1|AWH81039.1|1775720_1776158_+|hypothetical-protein
MLNNIIDGISIKLDKTFGESYTIYSEDVEQGINEPCFFIVPLNPSKVSYPSGRTLKKNSFDVHYFPKSNDKSFEINEVAEMLLEELEYIEIDGDLVRGTNMNFEIVDNVLHFFVDYNYFTIKSNNTDKMDTVELFGGLKRGDKLE
>CP029154.1|AWH81038.1|1775302_1775728_+|HK97-gp10-family-phage-protein
MARWGSVDFREFKRVCKKVEKLTKIDLDKFCKDAARELAARLLGKVIRRTPVDTGFLREGWSGVAYARSLPVYKQGNNYIIEVVNPTEYASYVNFGHRTKDGKGWVKGQHFLTISEMELQSQVDKIIEKKLLILLKGVFDA
>CP029154.1|AWH81037.1|1774955_1775303_+|hypothetical-protein
MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQPCKLSYKNIVSATEGKLAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPNHQEIILELFKDKA
>CP029154.1|AWH81036.1|1774560_1774962_+|hypothetical-protein
MENNIIDEIEKRLESFGYILKDGDKWLIGFVREKIENIIKLDCNIKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSGSQTPEQRFDSLIAYLTTYGKNKILTFRCLRW
>CP029154.1|AWH81046.1|1780286_1781039_+|SHOCT-domain-containing-protein
MGLFKKKEKEKGICIICGNEGNALKTVDNEFLCDECFEKCRGEIAVLGKGLKKLTSKEVMNAVELCRDNFGNFVKNTLIQIVYLGGHPLFNREEMICLLIRSDKIVVKAFGTGPVPIVDVFEVSYSDIKSVSIEKEEEVIRRYTATRIALFGPFALAMQKAELNKKEYLIIECNDFILSFDKNDEALATVYKNLIEYRKNNGIGNVSESEVEKNKITNPLEQIKTLKELLDMDAITQEEFDVKKKELLNL
>CP029154.1|AWH81047.1|1781342_1781516_+|CopG-family-transcriptional-regulator
MSSKMGRPKVDNPKNIDVKVRFDENTHKKLLDYCEKENLTRTEAIRKGVDLLLEEDR
>CP029154.1|AWH83303.1|1782071_1782467_+|hypothetical-protein
MLKELLDGAGFDNKSKLLTAKTLYKKAGIDLPIEIEEEESFFDTKQIASKLKIYSKSNKPAQLAVCEIIKKIKLEENEVKGVWETNGSWTGTVNKYTKSVIDKVRTWIEENNRPAKIEGEKKNFHVVYKIE
>CP029154.1|AWH81048.1|1783104_1783683_+|zinc-ribbon-domain-containing-protein
MLGGFVMFCSNCGAEITGVGKFCSSCGVAVETEIIEDNNIKSNDLIVDANGIEINMTEIYRKYRKEKVNAIKNVMEISGLNIKEAKKIVDSSFEELKINFIDDTMSNSEKEKIINTQNRKNNIEKAQQESVACCPKCGSTSLSAQKKGFGIGKAVAGATIAGGIGLVAGNLGAKKVRVTCLNCGKQFWAGKK
>CP029154.1|AWH81049.1|1783758_1786125_+|hypothetical-protein
MATIQTSIRIFDGMTPAFRHMTNAMNIVLSSFEQLQRTSSNAIDANSIRTAREELARAEAGFDRLEQQIREADEQQKRFNDDIRKGASSTDKLVENAKRLVATYIGLRSVGGLINLSDQMTSTNARLAMINDGQQSDGGLNKMIFQSAERARASYLDTAKIVSRVGMNAGKAFSSTKEIVAFAEQLNKKFVIAGATTEETNSALLQLTQGLGSGVLRGEELNAVFESAPNIIQSIADYLEVDIGKIRGMASEGMLTADIVKNSLLSAAEQTNAEFEKMPYTFGQIFTSIKNNAVMIFGVIQKKIEQSMSSKGFRTFIDNFIDSLYVLGAVAFSIFNGIINILGSPFFQAFVNAIIVGVSLIVQVLGWVITQALNITNVFAQNWSIIAPIVLGVAAAMLVYNNALLLSIANKVKDIALSAKTLAMNFAHIIAESYRAAALVASTIAQDGLNAAMAACPITWILYGIIAIVVAFFVAIAVINKFAGTSYSAIGIVAGALSGLTAFIINSVFFWINVFISFAEFFTNVLDHPVYSVKKLFFNLATAVLNNLISMTKGCDEFATNLANSIIDGINGALKAWNKFVDVLNKFGGLADKLGLGKADMVGHTKSITSTLQKAKGDLNKWLGAEPEGYKSFKQLEYKNVGDWAKNGYAFGQNLENKLKDAFDINKIAEKAKKDLGLDDLWDKKYGLGDGLGSAGLNSPLSDAAKGAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQEVINKYTGVNIKIDMNNTNNISKDTDLDGIVNVLTEKLNDAMVVSAEGVV
>CP029154.1|AWH81050.1|1786140_1786842_+|LysM-peptidoglycan-binding-domain-containing-protein
MAYDFYLDGVQLPIPPPKLEIKVTNKNKTVDLINTGEVNILKKEGLSEISFEAEFTHNKLPFYRGTFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFNTNMKVSLEEYNIVEDAENASDTKVAIKLKQYRDYSTKKLVLATPEKTNYGRTPPPVMKPKEFRPDSSNKPNAKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKSMMDKANKGKKVPKYTIYKGQVLKLG
>CP029154.1|AWH81051.1|1786834_1788799_+|cell-wall-hydrolase
MDDELVLANDRDVRLVIAHWEDFYEPVVLDGITWEIERRGTPSKLEFTIVMDDILEFCEGNSVRLYYKGVGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNKDTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKLSRVEENKTLFDMILTALDDTLREKKEMYTLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEESGKRDVYIAQDSTHMRSWGILQMFETVDKNMNEAEIKQKCDILLKLYNKKTKSLSLKNALGDIRVRAGCLVPVFLNLGDIKLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYSSSSYSSGNTNNKNEKQNGPAQSTTSKEDNDMINKLNKVFKNKLSNTGNIFVKYSNAYKVNAALMAAISIHETGNGSSSLCKNKNNFFGMKGMSFSSVDEGIKKGISNLSRNYIHTGRKTLERIRDKYAPLYDSPLNKDWVPGVGKFYKQITGSTYTSNNAGTGVGSNEEAEKNLKDTTYQVQNNNSNTLTNNNSKVSKVIQEAKNQLGKPYAWGGNGPKSFDCSGLMVWAFKRGAGINLPRVSADQSKDSRGKLLCNINDVKAGDLVFFKNEQGKVHHVGLYIGNDQYIHAPQTGDVVKISSLSGRQKKKHDFERARRFF
>CP029154.1|AWH81052.1|1788812_1789073_+|DUF2577-domain-containing-protein
MSQELLQIIKKAAMDAVETSNPIQIAFGTIESVNPLVVKIEQKASFEESFLIQTDTFKKYTDKKIGDKLVLIRMQGGQQYLILDRM
>CP029154.1|AWH81053.1|1789077_1789497_+|DUF2634-domain-containing-protein
MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLNIEKNRVDGICDDVEALKQTIFLILNTERYEHLIYSRNYGVELNDLIGEPISYVIPELERRITEALIQDDRIENIDNFEFQNIKGKVQCRFSVHTKYGNIKAEKVVSV
>CP029154.1|AWH81054.1|1789497_1790544_+|phage-tail-protein
MFELMTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTETYIAMDELLDQTFVDTASYYYLEKRCKERGITPLSATNTIAKGVFNIDIPLDSRFNLGEYNYIAIERISEKTYKMKCETAGPIFELGKLIPIEYIDGLETTELTEILINGEDEESEDSLRQRYYDSLNSQSFGGNIQNYKDEVNKLPDVGGVKVYPVWNGGGTVKLVIINSNFKVPSTDLVNLVQEEIDPNMKGEGLGLAPIGHRVTVEGVTSTTINISAEITYKSGYTWENIKSIAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDITNTMINEVKSNLTINSNSIVVRGEVVG

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Crispr_ID: CP029154_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029154_9

1782769-1782994

Orphan

I-A

Consensus_repeat	Method
GTTTTATATTAACTATGTGGTATGTAAAT	CRT
TTTTATATTAACTATGTGGTATGTAAAT	CRISPRCasFinder
TTTTATATTAACTATGTGGTATGTAAAT	PILER-CR

3 spacers

The CRISPR arrays of CP029154_9

>merge|CP029154|9|1782769-1782994|CRT,CRISPRCasFinder,PILER-CR
GAATTATATTAACAATGTGGTATGTAAATAATGAATTTTGAGAATCTACATAGGATTGAACTACTAATTTTATATTAACTATGTGGTATGTAAATACTAAATTAGAGGTCGAGAAGGCTATTGAATCAAAAGGTTTTATATTAACTATGTGGTATGTAAATTACACATTTTCTCAAATTTGGACTTCAATTAAAAATGTTTTATATTAACTATGTGGACTTAAAAT

>CP029154|9|4|1782769-1782994|CRT
GAATTATATTAACAATGTGGTATGTAAAT	AATGAATTTTGAGAATCTACATAGGATTGAACTACTA
ATTTTATATTAACTATGTGGTATGTAAAT	ACTAAATTAGAGGTCGAGAAGGCTATTGAATCAAAAG
GTTTTATATTAACTATGTGGTATGTAAAT	TACACATTTTCTCAAATTTGGACTTCAATTAAAAAT
GTTTTATATTAACTATGTGGACTTAAAAT

>CP029154|9|9|1782770-1782994|CRISPRCasFinder
AATTATATTAACAATGTGGTATGTAAAT	AATGAATTTTGAGAATCTACATAGGATTGAACTACTAA
TTTTATATTAACTATGTGGTATGTAAAT	ACTAAATTAGAGGTCGAGAAGGCTATTGAATCAAAAGG
TTTTATATTAACTATGTGGTATGTAAAT	TACACATTTTCTCAAATTTGGACTTCAATTAAAAATG
TTTTATATTAACTATGTGGACTTAAAAT

>CP029154|9|3|1782772-1782929|PILER-CR
TTATATTAACAATGTGGTATGTAAATAA	TGAATTTTGAGAATCTACATAGGATTGAACTACTAATT
TTATATTAACTATGTGGTATGTAAATAC	TAAATTAGAGGTCGAGAAGGCTATTGAATCAAAAGGTT
TTATATTAACTATGTGGTATGTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP029154.1\|AWH81054.1\|1789497_1790544_+\|phage-tail-protein	unknown	unknown	gnl\|CDD\|377414
CP029154.1\|AWH81050.1\|1786140_1786842_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|236880
CP029154.1\|AWH81051.1\|1786834_1788799_+\|cell-wall-hydrolase	unknown	unknown	gnl\|CDD\|366353
CP029154.1\|AWH81049.1\|1783758_1786125_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131723
CP029154.1\|AWH81055.1\|1790536_1791154_+\|DUF2313-domain-containing-protein	unknown	unknown	gnl\|CDD\|378379
CP029154.1\|AWH81046.1\|1780286_1781039_+\|SHOCT-domain-containing-protein	unknown	unknown	gnl\|CDD\|378276
CP029154.1\|AWH81053.1\|1789077_1789497_+\|DUF2634-domain-containing-protein	unknown	unknown	gnl\|CDD\|378510
CP029154.1\|AWH81045.1\|1778977_1779139_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH81041.1\|1776327_1777638_+\|phage-tail-protein	unknown	unknown	gnl\|CDD\|377435
CP029154.1\|AWH81056.1\|1791165_1792158_+\|phage-tail-protein	unknown	unknown	gnl\|CDD\|372197
CP029154.1\|AWH81057.1\|1793907_1794255_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH81052.1\|1788812_1789073_+\|DUF2577-domain-containing-protein	unknown	unknown	gnl\|CDD\|378501
CP029154.1\|AWH81039.1\|1775720_1776158_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH81048.1\|1783104_1783683_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|376345
CP029154.1\|AWH81040.1\|1776150_1776327_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH81043.1\|1778196_1778637_+\|phage-portal-protein	unknown	unknown	gnl\|CDD\|378084
CP029154.1\|AWH81047.1\|1781342_1781516_+\|CopG-family-transcriptional-regulator	unknown	unknown	unknown
CP029154.1\|AWH81042.1\|1777654_1778125_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378178
CP029154.1\|AWH81044.1\|1778636_1778831_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274054
CP029154.1\|AWH83303.1\|1782071_1782467_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP029154.1\|AWH81043.1\|1778196_1778637_+\|phage-portal-protein	gnl\|CDD\|378084	pfam08890, Phage_TAC_5, Phage XkdN-like tail assembly chaperone protein, TAC. This is a family of phage tail assembly chaperone proteins, TACs, from Gram-positive bacteriophages, in particular PBSX from Firmicutes.	8.20802e-57
CP029154.1\|AWH81051.1\|1786834_1788799_+\|cell-wall-hydrolase	gnl\|CDD\|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	3.03482e-33
CP029154.1\|AWH81049.1\|1783758_1786125_+\|hypothetical-protein	gnl\|CDD\|131723	TIGR02675, Mu-like_prophage_FluMu_protein_gp42, tape measure domain. Proteins containing this domain are strictly bacterial, including bacteriophage and prophage regions of bacterial genomes. Most members are 800 to 1800 amino acids long, making them among the longest predicted proteins of their respective phage genomes, where they are encoded in tail protein regions. This roughly 80-residue domain described here usually begins between residue 100 and 250. Many members are known or predicted to act as phage tail tape measure proteins, a minor tail component that regulates tail length.	8.61899e-15
CP029154.1\|AWH81055.1\|1790536_1791154_+\|DUF2313-domain-containing-protein	gnl\|CDD\|378379	pfam10076, DUF2313, Uncharacterized protein conserved in bacteria (DUF2313). Members of this family of proteins comprise various hypothetical and putative bacteriophage tail proteins.	1.41324e-41
CP029154.1\|AWH81046.1\|1780286_1781039_+\|SHOCT-domain-containing-protein	gnl\|CDD\|378276	pfam09851, SHOCT, Short C-terminal domain.	2.60785e-05
CP029154.1\|AWH81053.1\|1789077_1789497_+\|DUF2634-domain-containing-protein	gnl\|CDD\|378510	pfam10934, DUF2634, Protein of unknown function (DUF2634). Some members in this family of proteins are annotated as phage related, xkdS however currently there is no known function.	9.70876e-35
CP029154.1\|AWH81041.1\|1776327_1777638_+\|phage-tail-protein	gnl\|CDD\|377435	pfam04984, Phage_sheath_1, Phage tail sheath protein subtilisin-like domain. This entry represents the second domain in a variety of phage tail sheath proteins. According to ECOD this domain has a subtilisin-like structure.	2.35314e-37
CP029154.1\|AWH81056.1\|1791165_1792158_+\|phage-tail-protein	gnl\|CDD\|372197	pfam12571, DUF3751, Phage tail-collar fibre protein. This domain family is found in bacteria and viruses, and is approximately 160 amino acids in length. There are two completely conserved residues (K and W) that may be functionally important. The members are annotated as being putative phage tail or tail-collar proteins.	8.61741e-59
CP029154.1\|AWH81052.1\|1788812_1789073_+\|DUF2577-domain-containing-protein	gnl\|CDD\|378501	pfam10844, DUF2577, Protein of unknown function (DUF2577). This family of proteins has no known function.	6.31686e-18
CP029154.1\|AWH81054.1\|1789497_1790544_+\|phage-tail-protein	gnl\|CDD\|377414	pfam04865, Baseplate_J, Baseplate J-like protein. The P2 bacteriophage J protein lies at the edge of the baseplate. This family also includes a number of bacterial homologs, which are thought to have been horizontally transferred.	1.80205e-50
CP029154.1\|AWH81048.1\|1783104_1783683_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|376345	pfam00542, Ribosomal_L12, Ribosomal protein L7/L12 C-terminal domain.	0.00094009
CP029154.1\|AWH81050.1\|1786140_1786842_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	1.75254e-11
CP029154.1\|AWH81042.1\|1777654_1778125_+\|hypothetical-protein	gnl\|CDD\|378178	pfam09393, DUF2001, Phage tail tube protein. This is a family of phage tail tube proteins including protein XkdM from phage-like element PBSX protein whose structure adopts a beta barrel flanked with alpha helical regions.	2.40208e-57
CP029154.1\|AWH81044.1\|1778636_1778831_+\|hypothetical-protein	gnl\|CDD\|274054	TIGR02247, Hypothetical_protein_K09H11.1, epoxide hydrolase N-terminal domain-like phosphatase. This model represents a small clade of sequences including C. elegans and mammalian sequences as well as a small number of bacteria. In eukaryotes, this domain exists as an N-terminal fusion to the soluble epoxide hydrolase enzyme and has recently been shown to be an active phosphatase, although the nature of the biological substrate is unclear. These appear to be members of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases by general homology and the conservation of all of the recognized catalytic motifs (although the first motif is unusual in the replacement of the more common aspartate with glycine...). The variable domain is found in between motifs 1 and 2, indicating membership in subfamily I and phylogeny and prediction of the alpha helical nature of the variable domain (by PSI-PRED) indicate membership in subfamily IA.	0.00562027

>CP029154.1|AWH83303.1|1782071_1782467_+|hypothetical-protein
MLKELLDGAGFDNKSKLLTAKTLYKKAGIDLPIEIEEEESFFDTKQIASKLKIYSKSNKPAQLAVCEIIKKIKLEENEVKGVWETNGSWTGTVNKYTKSVIDKVRTWIEENNRPAKIEGEKKNFHVVYKIE
>CP029154.1|AWH81047.1|1781342_1781516_+|CopG-family-transcriptional-regulator
MSSKMGRPKVDNPKNIDVKVRFDENTHKKLLDYCEKENLTRTEAIRKGVDLLLEEDR
>CP029154.1|AWH81046.1|1780286_1781039_+|SHOCT-domain-containing-protein
MGLFKKKEKEKGICIICGNEGNALKTVDNEFLCDECFEKCRGEIAVLGKGLKKLTSKEVMNAVELCRDNFGNFVKNTLIQIVYLGGHPLFNREEMICLLIRSDKIVVKAFGTGPVPIVDVFEVSYSDIKSVSIEKEEEVIRRYTATRIALFGPFALAMQKAELNKKEYLIIECNDFILSFDKNDEALATVYKNLIEYRKNNGIGNVSESEVEKNKITNPLEQIKTLKELLDMDAITQEEFDVKKKELLNL
>CP029154.1|AWH81045.1|1778977_1779139_+|hypothetical-protein
MNNFLLNVIAGVIASLIFCLICKVFLKVKSHSTRGKSKSGWEFDFKIKFHKFK
>CP029154.1|AWH81044.1|1778636_1778831_+|hypothetical-protein
MRGGDFDASITHYCIQKLKWKPSEYMNLEVNERALAAASILIKIEDEEEAMKEAERERKRGRRR
>CP029154.1|AWH81043.1|1778196_1778637_+|phage-portal-protein
MSNLSAFLSQNAIKVDNVKYVASNRFLDKEGKPVEWELKVLSSEEDEALRRKCTKRVKVIGNNGKHTGQYTSEIDYNSYVAELCVASTVFPDLKDAELQNSYGVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTSFEDKVEEAKN
>CP029154.1|AWH81042.1|1777654_1778125_+|hypothetical-protein
MAQTINAKDTVSAKKAECFITIEGKRYNFMQAIDLEAKMEKNKSEVPILGRTTKGNKTTGSTNTGSATFHYNTSIFRELLYRYKETGEDIYFDIQVTNEDPTSAVGRQTVVLKDCNMDSGIITKFDADGEYLDEDMDFTFEDWELVEKFNLLAGME
>CP029154.1|AWH81041.1|1776327_1777638_+|phage-tail-protein
MALGGGTFVTQNKVLPGAYINFVSATRATSSLSDRGIVAIPLELDWGIDEEVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKASCTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITDLQDNDYITWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLFVEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVENKIKDKDLVESSLIYWAAGAIAGCDINKSNTNKKYDGEFDVDVNYTQIQLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTDDKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENIRAIEDFKTDDVSVELGNDKKTVIVSDAVKVINAMSKLYMTVSVS
>CP029154.1|AWH81040.1|1776150_1776327_+|hypothetical-protein
MSKTLSKEENYKFTKEQIVNSKRYVNRKDLLNAILKEDELYSFSEVEDMINNFMKGVS
>CP029154.1|AWH81039.1|1775720_1776158_+|hypothetical-protein
MLNNIIDGISIKLDKTFGESYTIYSEDVEQGINEPCFFIVPLNPSKVSYPSGRTLKKNSFDVHYFPKSNDKSFEINEVAEMLLEELEYIEIDGDLVRGTNMNFEIVDNVLHFFVDYNYFTIKSNNTDKMDTVELFGGLKRGDKLE
>CP029154.1|AWH81048.1|1783104_1783683_+|zinc-ribbon-domain-containing-protein
MLGGFVMFCSNCGAEITGVGKFCSSCGVAVETEIIEDNNIKSNDLIVDANGIEINMTEIYRKYRKEKVNAIKNVMEISGLNIKEAKKIVDSSFEELKINFIDDTMSNSEKEKIINTQNRKNNIEKAQQESVACCPKCGSTSLSAQKKGFGIGKAVAGATIAGGIGLVAGNLGAKKVRVTCLNCGKQFWAGKK
>CP029154.1|AWH81049.1|1783758_1786125_+|hypothetical-protein
MATIQTSIRIFDGMTPAFRHMTNAMNIVLSSFEQLQRTSSNAIDANSIRTAREELARAEAGFDRLEQQIREADEQQKRFNDDIRKGASSTDKLVENAKRLVATYIGLRSVGGLINLSDQMTSTNARLAMINDGQQSDGGLNKMIFQSAERARASYLDTAKIVSRVGMNAGKAFSSTKEIVAFAEQLNKKFVIAGATTEETNSALLQLTQGLGSGVLRGEELNAVFESAPNIIQSIADYLEVDIGKIRGMASEGMLTADIVKNSLLSAAEQTNAEFEKMPYTFGQIFTSIKNNAVMIFGVIQKKIEQSMSSKGFRTFIDNFIDSLYVLGAVAFSIFNGIINILGSPFFQAFVNAIIVGVSLIVQVLGWVITQALNITNVFAQNWSIIAPIVLGVAAAMLVYNNALLLSIANKVKDIALSAKTLAMNFAHIIAESYRAAALVASTIAQDGLNAAMAACPITWILYGIIAIVVAFFVAIAVINKFAGTSYSAIGIVAGALSGLTAFIINSVFFWINVFISFAEFFTNVLDHPVYSVKKLFFNLATAVLNNLISMTKGCDEFATNLANSIIDGINGALKAWNKFVDVLNKFGGLADKLGLGKADMVGHTKSITSTLQKAKGDLNKWLGAEPEGYKSFKQLEYKNVGDWAKNGYAFGQNLENKLKDAFDINKIAEKAKKDLGLDDLWDKKYGLGDGLGSAGLNSPLSDAAKGAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQEVINKYTGVNIKIDMNNTNNISKDTDLDGIVNVLTEKLNDAMVVSAEGVV
>CP029154.1|AWH81050.1|1786140_1786842_+|LysM-peptidoglycan-binding-domain-containing-protein
MAYDFYLDGVQLPIPPPKLEIKVTNKNKTVDLINTGEVNILKKEGLSEISFEAEFTHNKLPFYRGTFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFNTNMKVSLEEYNIVEDAENASDTKVAIKLKQYRDYSTKKLVLATPEKTNYGRTPPPVMKPKEFRPDSSNKPNAKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKSMMDKANKGKKVPKYTIYKGQVLKLG
>CP029154.1|AWH81051.1|1786834_1788799_+|cell-wall-hydrolase
MDDELVLANDRDVRLVIAHWEDFYEPVVLDGITWEIERRGTPSKLEFTIVMDDILEFCEGNSVRLYYKGVGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNKDTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKLSRVEENKTLFDMILTALDDTLREKKEMYTLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEESGKRDVYIAQDSTHMRSWGILQMFETVDKNMNEAEIKQKCDILLKLYNKKTKSLSLKNALGDIRVRAGCLVPVFLNLGDIKLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYSSSSYSSGNTNNKNEKQNGPAQSTTSKEDNDMINKLNKVFKNKLSNTGNIFVKYSNAYKVNAALMAAISIHETGNGSSSLCKNKNNFFGMKGMSFSSVDEGIKKGISNLSRNYIHTGRKTLERIRDKYAPLYDSPLNKDWVPGVGKFYKQITGSTYTSNNAGTGVGSNEEAEKNLKDTTYQVQNNNSNTLTNNNSKVSKVIQEAKNQLGKPYAWGGNGPKSFDCSGLMVWAFKRGAGINLPRVSADQSKDSRGKLLCNINDVKAGDLVFFKNEQGKVHHVGLYIGNDQYIHAPQTGDVVKISSLSGRQKKKHDFERARRFF
>CP029154.1|AWH81052.1|1788812_1789073_+|DUF2577-domain-containing-protein
MSQELLQIIKKAAMDAVETSNPIQIAFGTIESVNPLVVKIEQKASFEESFLIQTDTFKKYTDKKIGDKLVLIRMQGGQQYLILDRM
>CP029154.1|AWH81053.1|1789077_1789497_+|DUF2634-domain-containing-protein
MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLNIEKNRVDGICDDVEALKQTIFLILNTERYEHLIYSRNYGVELNDLIGEPISYVIPELERRITEALIQDDRIENIDNFEFQNIKGKVQCRFSVHTKYGNIKAEKVVSV
>CP029154.1|AWH81054.1|1789497_1790544_+|phage-tail-protein
MFELMTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTETYIAMDELLDQTFVDTASYYYLEKRCKERGITPLSATNTIAKGVFNIDIPLDSRFNLGEYNYIAIERISEKTYKMKCETAGPIFELGKLIPIEYIDGLETTELTEILINGEDEESEDSLRQRYYDSLNSQSFGGNIQNYKDEVNKLPDVGGVKVYPVWNGGGTVKLVIINSNFKVPSTDLVNLVQEEIDPNMKGEGLGLAPIGHRVTVEGVTSTTINISAEITYKSGYTWENIKSIAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDITNTMINEVKSNLTINSNSIVVRGEVVG
>CP029154.1|AWH81055.1|1790536_1791154_+|DUF2313-domain-containing-protein
MDKEINLINYLPQILQDKEEYIKVFNVENKEIKTLHDKLKDLSNDQFLEDLTISGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDNVVGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSNIKPCNMTLDYTRVLISKDNYMNFGITTLMGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF
>CP029154.1|AWH81056.1|1791165_1792158_+|phage-tail-protein
MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEYTPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNLIAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETKIGTVNTKIDTTKTELTSNIETAKTELNTKIDQLIAGGSNVAYTQRVAIDDWVEDAESGFKATVTHSLLTHRIVVNIIDATTKENIVPNFKIVDDNSIEIRSEVKVELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIEDRLVNIEEKVNGGLSNIATSVNELITYC
>CP029154.1|AWH81057.1|1793907_1794255_+|hypothetical-protein
MNRNNRIIYDQTGNIWLQTGEATGDIQEWSKITELNFLDVEFGSIDYSKQYIESINPVTKEPIIKDIEVILTDEQKRLQALEKELSMLKEENKNRDSEIVNTAFEVENIKLNNNL

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Crispr_ID: CP029154_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029154_10

1924167-1924586

Orphan

I-A

Consensus_repeat	Method
GTTTTATATTAACTATGTGGTATGTAAAT	PILER-CR
GTTTTATATTAACTATGTGGTATGTAAAT	CRISPRCasFinder
GTTTTATATTAACTATGTGGTATGTAAAT	CRT

6 spacers

The CRISPR arrays of CP029154_10

>merge|CP029154|10|1924167-1924586|PILER-CR,CRISPRCasFinder,CRT
GTTTTATATTAACTATGTGGTATGTAAATATTGTTTTACCTTCTAAAAGGTCACATATATTTATTGTTTTATATTAACTATGTGGTATGTAAATTCTATATCTGTTTCAAAATCTGTTATGAAATACTCCGTTTTATATTAACTATGTGGTATGTAAATAATAACTTATCTATGAAATTAAATACTGTAACTTGGTTTTATATTAACTATGTGGTATGTAAATTTGACCGACTTCATCAACTGCACCAGATTCTAATTCGTTTTATATTAACTATGTGGTATGTAAATTTTCAACAGTGGTGGTGGTCGAGGAGTAGAAGTTCTGTTTTATATTAACTATGTGGTATGTAAATTTTATAACCTTTAATTACACCTCCCATATCACCACCACGTTTTATATTAACTACGTGGTATGTAAAT

>CP029154|10|4|1924167-1924586|PILER-CR
GTTTTATATTAACTATGTGGTATGTAAAT	ATTGTTTTACCTTCTAAAAGGTCACATATATTTATT
GTTTTATATTAACTATGTGGTATGTAAAT	TCTATATCTGTTTCAAAATCTGTTATGAAATACTCC
GTTTTATATTAACTATGTGGTATGTAAAT	AATAACTTATCTATGAAATTAAATACTGTAACTTG
GTTTTATATTAACTATGTGGTATGTAAAT	TTGACCGACTTCATCAACTGCACCAGATTCTAATTC
GTTTTATATTAACTATGTGGTATGTAAAT	TTTCAACAGTGGTGGTGGTCGAGGAGTAGAAGTTCT
GTTTTATATTAACTATGTGGTATGTAAAT	TTTATAACCTTTAATTACACCTCCCATATCACCACCAC
GTTTTATATTAACTACGTGGTATGTAAAT

>CP029154|10|10|1924167-1924586|CRISPRCasFinder
GTTTTATATTAACTATGTGGTATGTAAAT	ATTGTTTTACCTTCTAAAAGGTCACATATATTTATT
GTTTTATATTAACTATGTGGTATGTAAAT	TCTATATCTGTTTCAAAATCTGTTATGAAATACTCC
GTTTTATATTAACTATGTGGTATGTAAAT	AATAACTTATCTATGAAATTAAATACTGTAACTTG
GTTTTATATTAACTATGTGGTATGTAAAT	TTGACCGACTTCATCAACTGCACCAGATTCTAATTC
GTTTTATATTAACTATGTGGTATGTAAAT	TTTCAACAGTGGTGGTGGTCGAGGAGTAGAAGTTCT
GTTTTATATTAACTATGTGGTATGTAAAT	TTTATAACCTTTAATTACACCTCCCATATCACCACCAC
GTTTTATATTAACTACGTGGTATGTAAAT

>CP029154|10|5|1924167-1924586|CRT
GTTTTATATTAACTATGTGGTATGTAAAT	ATTGTTTTACCTTCTAAAAGGTCACATATATTTATT
GTTTTATATTAACTATGTGGTATGTAAAT	TCTATATCTGTTTCAAAATCTGTTATGAAATACTCC
GTTTTATATTAACTATGTGGTATGTAAAT	AATAACTTATCTATGAAATTAAATACTGTAACTTG
GTTTTATATTAACTATGTGGTATGTAAAT	TTGACCGACTTCATCAACTGCACCAGATTCTAATTC
GTTTTATATTAACTATGTGGTATGTAAAT	TTTCAACAGTGGTGGTGGTCGAGGAGTAGAAGTTCT
GTTTTATATTAACTATGTGGTATGTAAAT	TTTATAACCTTTAATTACACCTCCCATATCACCACCAC
GTTTTATATTAACTACGTGGTATGTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP029154.1\|AWH81162.1\|1921042_1921360_-\|DUF1255-domain-containing-protein	unknown	unknown	gnl\|CDD\|377724
CP029154.1\|AWH81168.1\|1929979_1930564_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
CP029154.1\|AWH83307.1\|1923739_1923916_-\|integrase	unknown	unknown	gnl\|CDD\|271189
CP029154.1\|AWH81163.1\|1922250_1923522_-\|guanine-deaminase	unknown	unknown	gnl\|CDD\|238628
CP029154.1\|AWH81155.1\|1908109_1908907_-\|lipoprotein	unknown	unknown	gnl\|CDD\|224381
CP029154.1\|AWH81170.1\|1932409_1933432_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH81173.1\|1935223_1935949_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|223816
CP029154.1\|AWH81159.1\|1914245_1916720_+\|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPA	unknown	unknown	gnl\|CDD\|234769
CP029154.1\|AWH81160.1\|1916719_1918177_+\|glycine-dehydrogenase-subunit-2	unknown	unknown	gnl\|CDD\|235292
CP029154.1\|AWH81161.1\|1918599_1920957_+\|ATPase-P	unknown	unknown	gnl\|CDD\|319795
CP029154.1\|AWH81156.1\|1909216_1910203_-\|lipoate--protein-ligase	unknown	unknown	gnl\|CDD\|161920
CP029154.1\|AWH81157.1\|1910685_1912416_+\|Na+/H+-antiporter-NhaC-family-protein	unknown	unknown	gnl\|CDD\|224671
CP029154.1\|AWH81171.1\|1933445_1934333_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213231
CP029154.1\|AWH81169.1\|1931665_1931842_-\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH81164.1\|1924992_1925280_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH81165.1\|1925818_1926370_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380339
CP029154.1\|AWH81158.1\|1912940_1913456_+\|HXXEE-domain-containing-protein	unknown	unknown	gnl\|CDD\|379370
CP029154.1\|AWH81172.1\|1934338_1935112_+\|ABC-transporter-permease	unknown	unknown	unknown
CP029154.1\|AWH81167.1\|1927814_1929659_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176521
CP029154.1\|AWH81166.1\|1926560_1927523_+\|cysteine-synthase-family-protein	unknown	unknown	gnl\|CDD\|107204

Protein	Function_ID	Function_description	E-value
CP029154.1\|AWH81162.1\|1921042_1921360_-\|DUF1255-domain-containing-protein	gnl\|CDD\|377724	pfam06865, DUF1255, Protein of unknown function (DUF1255). This family consists of several conserved hypothetical bacterial proteins of around 95 residues in length. The function of this family is unknown.	2.10154e-53
CP029154.1\|AWH81168.1\|1929979_1930564_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	8.21183e-95
CP029154.1\|AWH83307.1\|1923739_1923916_-\|integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	8.52674e-06
CP029154.1\|AWH81163.1\|1922250_1923522_-\|guanine-deaminase	gnl\|CDD\|238628	cd01303, GDEase, Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and therefore can play a role in the regulation of cellular GTP and the guanylate nucleotide pool.	1.97927e-169
CP029154.1\|AWH81155.1\|1908109_1908907_-\|lipoprotein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	3.07907e-94
CP029154.1\|AWH81173.1\|1935223_1935949_+\|DNA-binding-response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.71451e-80
CP029154.1\|AWH81159.1\|1914245_1916720_+\|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPA	gnl\|CDD\|234769	PRK00451, PRK00451, aminomethyl-transferring glycine dehydrogenase subunit GcvPA.	0
CP029154.1\|AWH81160.1\|1916719_1918177_+\|glycine-dehydrogenase-subunit-2	gnl\|CDD\|235292	PRK04366, PRK04366, aminomethyl-transferring glycine dehydrogenase subunit GcvPB.	0
CP029154.1\|AWH81161.1\|1918599_1920957_+\|ATPase-P	gnl\|CDD\|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0
CP029154.1\|AWH81156.1\|1909216_1910203_-\|lipoate--protein-ligase	gnl\|CDD\|161920	TIGR00545, Probable_lipoate-protein_ligase_A, lipoyltransferase and lipoate-protein ligase. One member of this group of proteins is bovine lipoyltransferase, which transfers the lipoyl group from lipoyl-AMP to the specific Lys of lipoate-dependent enzymes. However, it does not first activate lipoic acid with ATP to create lipoyl-AMP and pyrophosphate. Another member of this group, lipoate-protein ligase A from E. coli, catalyzes both the activation and the transfer of lipoate. Homology between the two is full-length, except for the bovine mitochondrial targeting signal, but is strongest toward the N-terminus. [Protein fate, Protein modification and repair].	2.16968e-94
CP029154.1\|AWH81157.1\|1910685_1912416_+\|Na+/H+-antiporter-NhaC-family-protein	gnl\|CDD\|224671	COG1757, NhaC, Na+/H+ antiporter [Energy production and conversion].	1.25485e-57
CP029154.1\|AWH81171.1\|1933445_1934333_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213231	cd03264, ABC_drug_resistance_like, ABC-type multidrug transport system, ATPase component. The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	1.66751e-105
CP029154.1\|AWH81166.1\|1926560_1927523_+\|cysteine-synthase-family-protein	gnl\|CDD\|107204	cd01561, CBS_like, CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.	4.52734e-108
CP029154.1\|AWH81165.1\|1925818_1926370_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|380339	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain. This family contains transcriptional regulators containing an N-terminal XRE (Xenobiotic Response Element) family helix-turn-helix (HTH) DNA-binding domain and a C-terminal cupin domain. Included in this family is Escherichia coli transcription factor SutR (YdcN) that plays a regulatory role in sulfur utilization; it regulates a set of genes involved in the generation of sulfate and its reduction, the synthesis of cysteine, the synthesis of enzymes containing Fe-S as cofactors, and the modification of tRNA with use of sulfur-containing substrates. This family belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.67456e-17
CP029154.1\|AWH81158.1\|1912940_1913456_+\|HXXEE-domain-containing-protein	gnl\|CDD\|379370	pfam13787, HXXEE, Protein of unknown function with HXXEE motif. This domain contains an HXXEE motif, another conserved histidine and a YXPG motif. Its function is unknown.	1.48924e-21
CP029154.1\|AWH81167.1\|1927814_1929659_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176521	cd08579, GDPD_memb_like, Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized bacterial glycerophosphodiester phosphodiesterases. In addition to a C-terminal GDPD domain, most members in this family have an N-terminus that functions as a membrane anchor.	5.58257e-93

>CP029154.1|AWH83307.1|1923739_1923916_-|integrase
MLTILSILIVLLLAGTNIKIISERLGHTDIKITMNRYFLILYDMDKEASENIIKVIFK
>CP029154.1|AWH81163.1|1922250_1923522_-|guanine-deaminase
MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEYKNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEYATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPDTLLENTQDSIADTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPIQSHLSENYDEIEWVRNLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMRENNVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKLYWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSILERLERFIYVGDDRNIIHRYVCGKLIEEPNI
>CP029154.1|AWH81162.1|1921042_1921360_-|DUF1255-domain-containing-protein
MNEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEYTFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSYIAD
>CP029154.1|AWH81161.1|1918599_1920957_+|ATPase-P
MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFENGKTKTYKQIFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLSVIISNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGESDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKITNDAKISKKHNSQLRNSLNAILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAVGTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMGNICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEFIFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEAKETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYEAVDKYSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNVSNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPFVPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNIVEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGGLFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN
>CP029154.1|AWH81160.1|1916719_1918177_+|glycine-dehydrogenase-subunit-2
MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIEDMIDQDMARQSELNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHPYQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDHKRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNPSTLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFSTPHGGGGPGAGPVGVKKELVPFLPIPIIERKEDKYVLNYDREKSIGKIKNFYGNFGVLVRAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEANIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEAKEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR
>CP029154.1|AWH81159.1|1914245_1916720_+|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPA
MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEMVRKSAGIFDVSHMGEVQIKGVESEKFIQNLVTNDISTLNINDIIYTPMCYENGGVVDDLLIYKFGEEEYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQKITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVGGEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSKEKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKIVGFVTTGCASPTTGKILGMGIIDSEYAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKMLKVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLGAGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANASMYDGATAAIEACIMAINQTRKSKIVVSKTTHPETLSVLRTYLQYKDCEIVEIDFCNEYGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLGVLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGKIAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAHYTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELKNSTLLCVTEKRSKEEIDKLVGIMEGL
>CP029154.1|AWH81158.1|1912940_1913456_+|HXXEE-domain-containing-protein
MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKIYENYSTEGMAFAVFEEFILCIIFCILIVITDNQYVYLLWLGSFIAYTLHLVIHIGQSIIIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSLIGKFTKWMSNI
>CP029154.1|AWH81157.1|1910685_1912416_+|Na+/H+-antiporter-NhaC-family-protein
MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILTLIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSLADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFFDDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDAFESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISIDLDEGVAELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQLFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDGMKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFATGTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMGAGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFIGIQIIGKRVDEAEIELVE
>CP029154.1|AWH81156.1|1909216_1910203_-|lipoate--protein-ligase
MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKNQNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPIIDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALKVKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHDIKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDFFGKCDVAFVENKLIGIKHEENALRNTLDSIEINDYFLGADTDILVSGILGVK
>CP029154.1|AWH81155.1|1908109_1908907_-|lipoprotein
MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELLEELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMAGKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGLVSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPINDEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF
>CP029154.1|AWH81164.1|1924992_1925280_+|hypothetical-protein
MKKILYALYSFIVIIANFRLKEKNYNFILLAIFFILLLIQNGVLKTGYQNRATFYQDNYFNGEDKSDKIKFMTIKIFIFLSLPLCFNILFNYLTS
>CP029154.1|AWH81165.1|1925818_1926370_-|XRE-family-transcriptional-regulator
MSINTIIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDSNPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPTRNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAESMHTYHNQGEKTLKAVIINYYPV
>CP029154.1|AWH81166.1|1926560_1927523_+|cysteine-synthase-family-protein
MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFSKKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSMERARMMKALGAEVVLVEQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLDACNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETAAIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFAGFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL
>CP029154.1|AWH81167.1|1927814_1929659_+|glycerophosphodiester-phosphodiesterase
MQKRNLRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALFFIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPISIVLIILSVIILAFYAFFELTSVIICFNKSIKYEKIGLFELFKISFKKSIKLLYPKNILLFIFVILIIPLVNTVLISGFIGKIQIPDYILDYIKSDIVLNIIYMIFLLIIYILVIRWIFSIHEITLNTENFKRARKESVNLIKGKIIRTIIYSLILSLVVAIIGYVIYHSGVIFIGIWTKYYTDMEFLKNIFINRCIAFEEYFRLILSIFIFILDIGFISATYYQYKGVSISKNNIKKEKKSISKIVFNLVLILLISYIESVAFSSHVNGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASHAKADYAEIDVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVGEKIATLKEMIKYSKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKTILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFVWTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF
>CP029154.1|AWH81168.1|1929979_1930564_+|sugar-O-acetyltransferase
MTEREKMLAGELYDCGDIELLTQWHRAKDLVRDYNQTDSSDLEKKEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNVLIAPNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTIGDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK
>CP029154.1|AWH81169.1|1931665_1931842_-|hypothetical-protein
MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVETCLHQVLLLVSRYN
>CP029154.1|AWH81170.1|1932409_1933432_+|hypothetical-protein
MVNWEIKKLAKSKSMFISLGILVLILIISIFITPVLETESYYIDKEKGRIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTDEFSKKIELMSKKKLDNLSVNEYKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALKSKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRVVDNVVALKTNLSITKYVILNIGIELLMFEGWAMIAVFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLSVISNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAISLCFLVIKSDYISR
>CP029154.1|AWH81171.1|1933445_1934333_+|ABC-transporter-ATP-binding-protein
MNKLEIEKLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTLMKQITTLIKPDEGQILYNGEDIFKMDDDYRNILGYLPQEFGVYKNFTAKEFLQYIGALKGLRGKHLNIKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEPTAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKDILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSIVLRIVSEDIPCGANIQPVQAKFEDVYMFYFDLDDAREV
>CP029154.1|AWH81172.1|1934338_1935112_+|ABC-transporter-permease
MMYLVKAEMIKILKSKSVWIIWLFLLFFGFLLIRKFDVLDTYADIFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLLANGLTLSIINISFILLLGIRGFSFFDFKNLNEPIHNLWYFGNSNLNLTVIQMYIIVILTTIFASFIFAQIGLTLSSIFKSAVIPFILGGLIIAIPYFSVGFIPDKAIKFMSLTPNWIMMSQQIVRYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF
>CP029154.1|AWH81173.1|1935223_1935949_+|DNA-binding-response-regulator
MENRVLIIDDEVEILKLLETVLKKEGLSNIYTAKTKEEGLEVFKSINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVTKPFSPKEVAFRVKAHLRRLSYFSDIQNESKNLNNNEEKIISFGPYILNESRAELIKDGKSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLEDNPSKPEYILTIKGLGYKLAVKED

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Crispr_ID: CP029154_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029154_11

2724328-2724488

Unclear

Consensus_repeat	Method
TGAAATCCACTTAGTTAATCTTAAAC	CRISPRCasFinder
TAGGTTTAAGATTAACTAAGTGGATTTCA	PILER-CR

2 spacers

cas3,cas5,cas7,cas6,c2c9_V-U4

The CRISPR arrays of CP029154_11

>merge|CP029154|11|2724328-2724488|CRISPRCasFinder,PILER-CR
AAAAATCCGATTAGTTAATTTTAAACCTAATAATAAAACTTCTATTATATCTACTATATCAATATTTGAAATCCACTTAGTTAATCTTAAACATACAAAATCTCCAACTTATAATTATTTTCGTGATGTACCTGAAACCCACTTAGTTAATCTTAAACCTC

>CP029154|11|11|2724328-2724485|CRISPRCasFinder
AAAAATCCGATTAGTTAATTTTAAAC	CTAATAATAAAACTTCTATTATATCTACTATATCAATATT
TGAAATCCACTTAGTTAATCTTAAAC	ATACAAAATCTCCAACTTATAATTATTTTCGTGATGTACC
TGAAACCCACTTAGTTAATCTTAAAC

>CP029154|11|5|2724330-2724488|PILER-CR
AAATCCGATTAGTTAATTTTAAACCTAAT	AATAAAACTTCTATTATATCTACTATATCAATATTTG
AAATCCACTTAGTTAATCTTAAACATACA	AAATCTCCAACTTATAATTATTTTCGTGATGTACCTG
AAACCCACTTAGTTAATCTTAAACCTC

Protein	Signature genes	Signature genes Name	Protein_function
CP029154.1\|AWH81888.1\|2730380_2731118_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
CP029154.1\|AWH81885.1\|2727063_2727861_-\|CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|187789
CP029154.1\|AWH81889.1\|2731926_2733090_+\|transposase	c2c9_V-U4	-	gnl\|CDD\|223747
CP029154.1\|AWH81890.1\|2733242_2734352_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|236947
CP029154.1\|AWH81874.1\|2716784_2718128_-\|sporulation-protein-YqfD	unknown	unknown	gnl\|CDD\|377731
CP029154.1\|AWH81878.1\|2719955_2720399_-\|GatB/YqeY-domain-containing-protein	unknown	unknown	gnl\|CDD\|370480
CP029154.1\|AWH81879.1\|2720428_2720608_-\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
CP029154.1\|AWH81887.1\|2728909_2730376_-\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH81892.1\|2735336_2736710_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
CP029154.1\|AWH81893.1\|2736745_2737681_-\|ROK-family-protein	unknown	unknown	gnl\|CDD\|224851
CP029154.1\|AWH81880.1\|2720770_2721121_-\|histidine-triad-nucleotide-binding-protein	unknown	unknown	gnl\|CDD\|238607
CP029154.1\|AWH81883.1\|2723240_2724188_-\|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|283886
CP029154.1\|AWH81882.1\|2722463_2723222_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|236959
CP029154.1\|AWH81877.1\|2719347_2719845_-\|tryptophan-rich-sensory-protein	unknown	unknown	gnl\|CDD\|320706
CP029154.1\|AWH81875.1\|2718140_2718383_-\|sporulation-protein	unknown	unknown	gnl\|CDD\|377934
CP029154.1\|AWH81881.1\|2721163_2722462_-\|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	unknown	unknown	gnl\|CDD\|223694
CP029154.1\|AWH81891.1\|2734381_2735149_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
CP029154.1\|AWH81876.1\|2718591_2719155_-\|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl\|CDD\|238308
CP029154.1\|AWH81886.1\|2727876_2728890_-\|DevR-family-CRISPR-associated-autoregulator	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
CP029154.1\|AWH81884.1\|2724628_2727037_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124

Protein	Function_ID	Function_description	E-value
CP029154.1\|AWH81888.1\|2730380_2731118_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	5.03192e-16
CP029154.1\|AWH81885.1\|2727063_2727861_-\|CRISPR-associated-protein-Cas5	gnl\|CDD\|187789	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	9.55327e-11
CP029154.1\|AWH81889.1\|2731926_2733090_+\|transposase	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.39282e-31
CP029154.1\|AWH81890.1\|2733242_2734352_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	0
CP029154.1\|AWH81874.1\|2716784_2718128_-\|sporulation-protein-YqfD	gnl\|CDD\|377731	pfam06898, YqfD, Putative stage IV sporulation protein YqfD. This family consists of several putative bacterial stage IV sporulation (SpoIV) proteins. YqfD of Bacillus subtilis is known to be essential for efficient sporulation although its exact function is unknown.	2.41878e-105
CP029154.1\|AWH81878.1\|2719955_2720399_-\|GatB/YqeY-domain-containing-protein	gnl\|CDD\|370480	pfam09424, YqeY, Yqey-like protein. The function of this domain found in the YqeY protein is uncertain.	3.14843e-57
CP029154.1\|AWH81879.1\|2720428_2720608_-\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	1.30053e-12
CP029154.1\|AWH81892.1\|2735336_2736710_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.01533e-34
CP029154.1\|AWH81893.1\|2736745_2737681_-\|ROK-family-protein	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	2.61583e-66
CP029154.1\|AWH81880.1\|2720770_2721121_-\|histidine-triad-nucleotide-binding-protein	gnl\|CDD\|238607	cd01276, PKCI_related, Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a hydrophobic residue) that is a signature for this family. No enzymatic activity has been reported however, for PKCI and its related members.	1.77543e-54
CP029154.1\|AWH81883.1\|2723240_2724188_-\|50S-ribosomal-protein-L11-methyltransferase	gnl\|CDD\|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	5.49183e-110
CP029154.1\|AWH81882.1\|2722463_2723222_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|236959	PRK11713, PRK11713, 16S ribosomal RNA methyltransferase RsmE; Provisional.	7.40285e-85
CP029154.1\|AWH81877.1\|2719347_2719845_-\|tryptophan-rich-sensory-protein	gnl\|CDD\|320706	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family. This family contains tryptophan-rich translocator protein (TSPO), an integral membrane protein that is highly conserved from bacteria to mammals. In eukaryotes, it is mainly found in the outer mitochondrial membranes of steroid-synthesizing cells of the nervous system where it transports cholesterol into mitochondria. It is known to be highly expressed in metastatic cancer, steriodogenic tissues, as well as inflammatory and neurological diseases such as Alzheimer's and Parkinson's. TSPO is also known as the peripheral benzodiazepine receptor (MBR) and its ligands include benzodiazepine drugs, implicated in regulating apoptosis. In human, a single polymorphism A147T is associated with psychiatric disorders; the mutation causes structural changes in a region implicated in cholesterol binding. TSPO is homologous to bacterial tryptophan-rich sensory proteins, and their tryptophan residues are believed to be functionally important. In bacteria, TSPO acts as a negative regulator of expression of specific photosynthesis genes in response to oxygen/light; it catalyzes a photooxidative degradation of Proto porphyrine (PpIX). R. sphaeroides TSPO (RsTSPO) is involved in porphyrin transport, similar to human, while Arabidopsis translocator protein (AtTSPO) is regulated at multiple levels in response to salt stress and perturbations in tetrapyrrole metabolism.	1.41313e-43
CP029154.1\|AWH81875.1\|2718140_2718383_-\|sporulation-protein	gnl\|CDD\|377934	pfam07873, YabP, YabP family. This family of proteins is involved in spore coat assembly during the process of sporulation.	1.05367e-12
CP029154.1\|AWH81881.1\|2721163_2722462_-\|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	gnl\|CDD\|223694	COG0621, MiaB, 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis].	6.08201e-179
CP029154.1\|AWH81891.1\|2734381_2735149_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	1.02765e-15
CP029154.1\|AWH81876.1\|2718591_2719155_-\|ribosome-associated-translation-inhibitor-RaiA	gnl\|CDD\|238308	cd00552, RaiA, RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY, is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal A site. RaiA is also thought to counteract miscoding at the A site thus reducing translation errors. The RaiA fold structurally resembles the double-stranded RNA-binding domain (dsRBD).	1.43831e-27
CP029154.1\|AWH81886.1\|2727876_2728890_-\|DevR-family-CRISPR-associated-autoregulator	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	1.28862e-18
CP029154.1\|AWH81884.1\|2724628_2727037_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	5.95142e-42

>CP029154.1|AWH81883.1|2723240_2724188_-|50S-ribosomal-protein-L11-methyltransferase
MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKKNELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGSVSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQDGDLIIELDPGMAFGTGTHETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKENVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISSGIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKR
>CP029154.1|AWH81882.1|2722463_2723222_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICDKNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEVGVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEALEDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNCNVVSLGPRILRTETASVVASTIALYELSDLGGEK
>CP029154.1|AWH81881.1|2721163_2722462_-|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB
MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVINTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDRRKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCIIPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQINQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYTTLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLREIELSQMHIFKYSPRKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKYEGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL
>CP029154.1|AWH81880.1|2720770_2721121_-|histidine-triad-nucleotide-binding-protein
MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKKHYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHILAGKKLPNYEAGQN
>CP029154.1|AWH81879.1|2720428_2720608_-|30S-ribosomal-protein-S21
MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVKRKKKAEAARRKNAKK
>CP029154.1|AWH81878.1|2719955_2720399_-|GatB/YqeY-domain-containing-protein
MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVELDEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEIVKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ
>CP029154.1|AWH81877.1|2719347_2719845_-|tryptophan-rich-sensory-protein
MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQLTKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWSILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFIWFINK
>CP029154.1|AWH81876.1|2718591_2719155_-|ribosome-associated-translation-inhibitor-RaiA
MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAKKDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKSIRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFYMFRNQDNFEINIVYKRKAGGYGLIEQD
>CP029154.1|AWH81875.1|2718140_2718383_-|sporulation-protein
MLMLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTKVKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD
>CP029154.1|AWH81874.1|2716784_2718128_-|sporulation-protein-YqfD
MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKMEFHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTSQFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSINVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKGDVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKNIKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKKNKEELKKELSEKALKELEYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPDEGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN
>CP029154.1|AWH81884.1|2724628_2727037_-|CRISPR-associated-helicase/endonuclease-Cas3
MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNLYSDKDVEILKICCVLHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIARHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSTSKVQEEIYEYIEKGILEKEEFNLKDIESYINDILNVDFKFDEDVLDYDYIDKLSESMFIDSDYNNGQIDDSVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILSEIYKSQGNLEKNNIKFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYRKNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCVIATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDVDFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVSFIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRFKFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNNKYEYGNFYILPSEDKIYDNKLKNTTKSILNKIIKTNSIFTMGIRKIILADYYDNSVVKKYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSYKIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVGLILK
>CP029154.1|AWH81885.1|2727063_2727861_-|CRISPR-associated-protein-Cas5
MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYLCDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLKGNYYDYYKEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPSEKGCFVKEVELKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPHKYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL
>CP029154.1|AWH81886.1|2727876_2728890_-|DevR-family-CRISPR-associated-autoregulator
MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHAKTSIATITYDLRRKLHQEYGWNLSNIIFGKKGNIYPSIKKNVGCVDENGLETDVFGYLIPLKDKGSISKASPLRIIPFRSLNPYRGSTQLITNRGFLSSEFGRKYYDEKEENEVLRDENFPTTQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKAVKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGVIETIESYSLKESNTILAINDRLKISNKKELNRFNLSKYPVKEIKNLADRLEIGEDNMWYLKE
>CP029154.1|AWH81887.1|2728909_2730376_-|hypothetical-protein
MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFTCELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFIEELDKSSATEKQKEEIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVNTVIKSNIEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKRSGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKSFYKKLLHEKISSIRLYRFDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREPGNTKNLGKKMIDNGNLSNLKELLLDNISVLKQSTGTSREMDFVSSSYNIGLYIKLCWIVDGGEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRAQLFQTIMHVLVSNGILIGEGFVEGIMQSSELELNTNVGIFIQEIMK
>CP029154.1|AWH81888.1|2730380_2731118_-|CRISPR-associated-endoribonuclease-Cas6
MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFNYGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKVKELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLNYIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKVREYYYINAYAGTFFLKGNMEDLNALYKMGIGYRRTENAGMVDILK
>CP029154.1|AWH81889.1|2731926_2733090_+|transposase
MKRAYKIEINPTTEQKSKIHQTIGVSRFIYNFYIAHNKEVYDSKGEFISGMDFSKCLNNEYIPNNQDMKWIKDISFKATKQAIMNGDKAFKDFFKKTKGFPKFKKKKNQDVKAYFPKNNKTDWTIERHRVKIPTLGWVRLKEFGYIPINSIVKSGTVSQKSDRYYVSILVEEDDIQVSKCTNEGIGIDLGIKDFAICSNGSKFKNINKTSTVKKVEKKLKREQRKLSRKYESLKVRNKNIKEGVATRQNIQKQIVKVQKIHQRLANIRTDYINKTVSQVIEQKPSYITIEDLNVSGMMKNKHLSKAISSQKFFEFRTKLTAKCKQNNIELRVVDRWYPSSKTCSQCGEVNKGLKLKDRVYKCECGLSIDRDLNASINLKNAKKYKIA
>CP029154.1|AWH81890.1|2733242_2734352_+|ABC-transporter-ATP-binding-protein
MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKSTTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALKLRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDEPLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGMVQQIATPQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKDNYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITIRFDSKNRINVGDDLTLSVDNSRIHIFDKETTLAIR
>CP029154.1|AWH81891.1|2734381_2735149_+|PucR-family-transcriptional-regulator
MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNSIYVIDFLDKNNLDNLKGNFYLIYQPHIEFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINVTTQNIIETETYQSTYIFYLGKLDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLIRYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGLKFINNDLNISKTSTSMFLHRNTLVYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI
>CP029154.1|AWH81892.1|2735336_2736710_-|MFS-transporter
MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISFTTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILIFIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLGGWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMIFILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQFIILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGRWIDKSGTRFPLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDSIGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILKKELRKVE
>CP029154.1|AWH81893.1|2736745_2737681_-|ROK-family-protein
MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILNDIKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPDVEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEIGHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNAKMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGIEDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL

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Crispr_ID: CP029154_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029154_12

2814077-2814365

Orphan

NA:I-A

Consensus_repeat	Method
ANTCCATATAGTNTAATATAAAAC	CRT
GGTTTTATATTAACTATATGGAATGTAAATT	PILER-CR

4 spacers

The CRISPR arrays of CP029154_12

>merge|CP029154|12|2814077-2814365|CRT,PILER-CR
GTACACAGGTTTGAATATAAAAAAGCACCTACCACAAAAGTAAGTGTTTTTCAGTATTTTTAATTTTAAGTCCATATAGTTAATATAAAACCTTAAAGCTACATAATAAAAAATTAAGAAAAAGAAAAATTTACATTCCATATAGTTAATATAAAACCATTCATAATCAAAAATGACAATACAGTATGGTCATGATTTACATTCCATATAGTTAATATAAAACTACATTATATAAGATAGCTAAAAATCTTTTAGGCAAATTTACATTCCATATAGTTAATATAAAACC

>CP029154|12|6|2814077-2814364|CRT
GTACACAGGTTTGAATATAAAAA	AGCACCTACCACAAAAGTAAGTGTTTTTCAGTATTTTTAATTTTA
AGTCCATATAGTTAATATAAAAC	CTTAAAGCTACATAATAAAAAATTAAGAAAAAGAAAAATTTAC
ATTCCATATAGTTAATATAAAAC	CATTCATAATCAAAAATGACAATACAGTATGGTCATGATTTAC
ATTCCATATAGTTAATATAAAAC	TACATTATATAAGATAGCTAAAAATCTTTTAGGCAAATTTAC
ATTCCATATAGTTAATATAAAAC

>CP029154|12|6|2814138-2814365|PILER-CR
AATTTTAAGTCCATATAGTTAATATAAAACC	TTAAAGCTACATAATAAAAAATTAAGAAAAAGAAA
AATTTACATTCCATATAGTTAATATAAAACC	ATTCATAATCAAAAATGACAATACAGTATGGTCAT
GATTTACATTCCATATAGTTAATATAAAACT	ACATTATATAAGATAGCTAAAAATCTTTTAGGCA
AATTTACATTCCATATAGTTAATATAAAACC

Protein	Signature genes	Signature genes Name	Protein_function
CP029154.1\|AWH81969.1\|2824671_2825310_+\|regulatory-protein-RecX	unknown	unknown	gnl\|CDD\|234646
CP029154.1\|AWH81957.1\|2812542_2812704_+\|cyclic-lactone-autoinducer-peptide	unknown	unknown	gnl\|CDD\|275064
CP029154.1\|AWH81962.1\|2816934_2817357_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379665
CP029154.1\|AWH81956.1\|2811943_2812525_+\|accessory-regulator	unknown	unknown	gnl\|CDD\|377395
CP029154.1\|AWH81963.1\|2818342_2819011_-\|VanZ-family-protein	unknown	unknown	gnl\|CDD\|377417
CP029154.1\|AWH81958.1\|2812725_2813523_-\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|119407
CP029154.1\|AWH81953.1\|2809530_2809707_+\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH81951.1\|2807587_2808583_+\|asparaginase	unknown	unknown	gnl\|CDD\|199208
CP029154.1\|AWH81955.1\|2810563_2811901_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|340412
CP029154.1\|AWH81968.1\|2823706_2824396_-\|nicotinate-nucleotide-adenylyltransferase	unknown	unknown	gnl\|CDD\|234611
CP029154.1\|AWH81967.1\|2823133_2823706_-\|HDIG-domain-containing-protein	unknown	unknown	gnl\|CDD\|224627
CP029154.1\|AWH81965.1\|2819892_2822313_-\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
CP029154.1\|AWH81952.1\|2808767_2809151_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|367747
CP029154.1\|AWH81964.1\|2819109_2819493_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
CP029154.1\|AWH81959.1\|2813519_2813780_-\|holin	unknown	unknown	gnl\|CDD\|379763
CP029154.1\|AWH81966.1\|2822666_2823017_-\|ribosome-silencing-factor	unknown	unknown	gnl\|CDD\|376779
CP029154.1\|AWH81954.1\|2809932_2810133_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
CP029154.1\|AWH81961.1\|2815165_2816536_-\|cell-wall-binding-protein-Cwp29	unknown	unknown	gnl\|CDD\|380277
CP029154.1\|AWH81950.1\|2805838_2807467_+\|aspartate-4-decarboxylase	unknown	unknown	gnl\|CDD\|163513
CP029154.1\|AWH81960.1\|2814649_2814808_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP029154.1\|AWH81969.1\|2824671_2825310_+\|regulatory-protein-RecX	gnl\|CDD\|234646	PRK00117, recX, recombination regulator RecX; Reviewed.	5.42744e-47
CP029154.1\|AWH81957.1\|2812542_2812704_+\|cyclic-lactone-autoinducer-peptide	gnl\|CDD\|275064	TIGR04223, quorum_AgrD, cyclic lactone autoinducer peptide. Members of this family of short peptides are precursors to thiolactone (unless Cys is replaced by Ser) cyclic autoinducer peptides, used in quorum-sensing systems in Gram-positive bacteria. The best characterized is the AgrD precursor, processed by the AgrB protein. Nearby proteins regularly encountered include a histidine kinase and a response regulator. This model is related to pfam05931 but is newer and currently broader in scope.	2.77025e-09
CP029154.1\|AWH81956.1\|2811943_2812525_+\|accessory-regulator	gnl\|CDD\|377395	pfam04647, AgrB, Accessory gene regulator B. The arg locus consists of two transcripts: RNAII and RNAIII. RNAII encodes four genes (agrA, B, C, and D) whose gene products assemble a quorum sensing system. AgrB and AgrD are essential for the production of the autoinducing peptide which functions as a signal for quorum sensing. AgrB is a transmembrane protein.	1.2276e-18
CP029154.1\|AWH81963.1\|2818342_2819011_-\|VanZ-family-protein	gnl\|CDD\|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	5.76794e-18
CP029154.1\|AWH81958.1\|2812725_2813523_-\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	7.07575e-32
CP029154.1\|AWH81951.1\|2807587_2808583_+\|asparaginase	gnl\|CDD\|199208	cd08964, L-asparaginase_II, Type II (periplasmic) bacterial L-asparaginase. Asparaginases (amidohydrolases, E.C. 3.5.1.1) are enzymes that catalyze the hydrolysis of asparagine to aspartic acid and ammonia. In bacteria, there are two classes of amidohydrolases. This model represents type II L-asparaginases, which tend to be highly specific for asparagine and localized to the periplasm. They are potent antileukemic agents and have been used in the treatment of acute lymphoblastic leukemia (ALL), but not without severe side effects. Tumor cells appear to have a heightened dependence on exogenous L-aspartate, and depleting their surroundings of L-aspartate may starve cancerous ALL cells. Type II L-asparaginase acts as a tetramer, which is actually a dimer of two tightly bound dimers. A conserved threonine residue is thought to supply the nucleophile hydroxy-group that attacks the amide bond. Many bacterial L-asparaginases have both L-asparagine and L-glutamine hydrolysis activities, to a different degree, and some of them are annotated as asparaginase/glutaminase.	8.27962e-141
CP029154.1\|AWH81955.1\|2810563_2811901_+\|ATP-binding-protein	gnl\|CDD\|340412	cd16935, HATPase_AgrC-ComD-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Staphylococcus aureus AgrC and Streptococcus pneumoniae ComD which are involved in quorum sensing. This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Staphylococcus aureus AgrC which is an HK of the accessory gene regulator (agr) quorum sensing two-component regulatory system (TCS) AgrC-AgrA. The agr system plays a part in the transition from persistent to virulent phenotype. This family also includes Streptococcus pneumoniae ComD HK of the ComD-ComE TCS, involved in quorum sensing and genetic competence.	2.72321e-33
CP029154.1\|AWH81968.1\|2823706_2824396_-\|nicotinate-nucleotide-adenylyltransferase	gnl\|CDD\|234611	PRK00071, nadD, nicotinate-nucleotide adenylyltransferase.	9.36329e-79
CP029154.1\|AWH81950.1\|2805838_2807467_+\|aspartate-4-decarboxylase	gnl\|CDD\|163513	TIGR03801, For_A_Pyridoxal-5-_Phosphate, aspartate 4-decarboxylase. This enzyme, aspartate 4-decarboxylase (EC 4.1.1.12), removes the side-chain carboxylate from L-aspartate, converting it to L-alanine plus carbon dioxide. It is a PLP-dependent enzyme, homologous to aspartate aminotransferase (EC 2.6.1.1). [Energy metabolism, Amino acids and amines].	0
CP029154.1\|AWH81965.1\|2819892_2822313_-\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
CP029154.1\|AWH81952.1\|2808767_2809151_-\|transcriptional-regulator	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	3.36102e-18
CP029154.1\|AWH81964.1\|2819109_2819493_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	0.000449607
CP029154.1\|AWH81959.1\|2813519_2813780_-\|holin	gnl\|CDD\|379763	pfam16079, Phage_holin_5_2, Phage holin family Hol44, in holin superfamily V. Phage_holin_V_2 is a family of small hydrophobic proteins with three transmembrane domains of the Hol44 family. These proteins are produced by double-stranded DNA bacteriophages that use an endolysin-holin strategy to achieve lysis of their hosts. The endolysins are peptidoglycan-degrading enzymes that are usually accumulated in the cytosol until access to the cell wall substrate is provided by the holin membrane lesion. Full activity of the endolysin Lys44 from oenophage fOg44 requires sudden ion-nonspecific dissipation of the proton motive force, undertaken by the fOg44 holin during phage-infection.	5.01487e-15
CP029154.1\|AWH81966.1\|2822666_2823017_-\|ribosome-silencing-factor	gnl\|CDD\|376779	pfam02410, RsfS, Ribosomal silencing factor during starvation. This family is expressed by almost all bacterial and eukaryotic genomes but not by archaea. Its function is to down-regulate protein synthesis under conditions of nutrient shortage, and it does this by binding to protein L14 of the large ribosomal subunit, thus acting as a ribosomal silencing factor (RsfS) by blocking the joining of the ribosomal subunits. This family is structurally homologous to nucleotidyltransferases.	7.43119e-49
CP029154.1\|AWH81962.1\|2816934_2817357_+\|hypothetical-protein	gnl\|CDD\|379665	pfam14659, Phage_int_SAM_3, Phage integrase, N-terminal SAM-like domain. This domain is found in a variety of phage integrase proteins.	3.221e-08
CP029154.1\|AWH81961.1\|2815165_2816536_-\|cell-wall-binding-protein-Cwp29	gnl\|CDD\|380277	NF033435, S-layer_Clost, S-layer protein SlpA. In Clostridiodes difficile, the S-layer protein precursor, SlpA, is one member of a large paralogous family of protein that share several cell wall-binding repeats. SlpA is cleaved into a larger and smaller protein. The S-layer protein itself is important to adhesion, and portions of it are highly variable, and then N-terminal and C-terminal are well-conserved.	2.18991e-18
CP029154.1\|AWH81954.1\|2809932_2810133_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.41551e-31
CP029154.1\|AWH81967.1\|2823133_2823706_-\|HDIG-domain-containing-protein	gnl\|CDD\|224627	COG1713, COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism].	4.17724e-52

>CP029154.1|AWH81959.1|2813519_2813780_-|holin
MDNLISFIPEQLLLLVVALNVLGFGFKKYKQLDNKYISVILLALGIVFSIWMLGFNPSSILQGILCWGVAIGANQVYKQLKDGEKQ
>CP029154.1|AWH81958.1|2812725_2813523_-|N-acetylmuramoyl-L-alanine-amidase
MKIAIVPGHTLSGKGTGATGYIDEGKENRILTDLIVKWLKQGGATVYTGKVDKSNNYLAEQCQIANKQNVDLAVQIHFNANKTTLNPMGTETICKTNNGKVYAERVNKKLSTIFKNRGAKSDVRGLYWLSHTKAPAILIEVCFVDSKADTDYYIRHKDIVAKLIAEGILNKKIDNDGVKLMYKHAIVYDGEVDKIPATVVGWGYNDGKILICDIKDYIPGQTENLYVVGGGACEKIGSMAKENYTLIKGNGRFDTLYKALDFIDR
>CP029154.1|AWH81957.1|2812542_2812704_+|cyclic-lactone-autoinducer-peptide
MKKILYNFMKACGVLAMFVAFLSANTTSLWHVYQPKTPEKLKNSKNHQKEGNN
>CP029154.1|AWH81956.1|2811943_2812525_+|accessory-regulator
MIKSCADKIAFLFVLNQVIEKDDLEICSYGLEILLSSIINTLSSLMIGLILGRLIYSIVFLISFCIIRQFSGGYHANSNKNCILIFNSIFFISMVLGTILNNSNPIPLFLVILSSFNFLIIFIFAPVCHTNNPLNETKYKKNKLLSRTISITLFLIILLGCKYLSFYNYVVYTFLALLWINLLLIIQIIINKK
>CP029154.1|AWH81955.1|2810563_2811901_+|ATP-binding-protein
MESFIMLDMFITIVSSIIEIWACKKVFDYTSKVKTSLINLYFLISTFIIISTFYTNVGADNRILICIFVMFVFYKSNYDVNIYKCLIVLFSYWAILVCINALSMIVIVSINNLSSMNILLNDNFYRYETIVLGNVVLIVLLCIYKFISNDLQVTKKEIYMCIPIVANMISFFIFYKYILKLLDISSATRLDILIMVLLLTFSNIVLISSLVKILKSNKKYIELTKLQEKINAENKYYSNIKKYYIKTKELNHDMKNHLICIKEMNKKNIDTSNYINNIEKKLDEYSAVFDTGNITLNIILLEKKELCIEKGIDFTININFSDCNFIKEEDTCSIFANALDNAIEACEKIKDDDKKIKLQGMVLNKFFVIKITNTKSNDILLKNNAFLTTKEDKEFHGLGIKSIKNSLEKYDGAISINFSENLFCLNMMIPIRKSQEDSNIAYENS
>CP029154.1|AWH81954.1|2809932_2810133_+|cold-shock-protein
MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEGQQVSFDIVKGARGPQAENITIL
>CP029154.1|AWH81953.1|2809530_2809707_+|hypothetical-protein
MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENIVESCLHQVMVLISKYN
>CP029154.1|AWH81952.1|2808767_2809151_-|transcriptional-regulator
MLNKKLPDIELKIMKYIWSTGYKTVISKDVADEIEKTYGWKHTTTITLLVRLTKKDFLISQRIGKHVHYRVLIKEREYLKIEGKRIFGGLHNNPLSELILKLHNEEEITEEKIIEIGSWIKSWKDED
>CP029154.1|AWH81951.1|2807587_2808583_+|asparaginase
MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNIDKVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFLDLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLASEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYVGENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVFDSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC
>CP029154.1|AWH81950.1|2805838_2807467_+|aspartate-4-decarboxylase
MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAGRGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDMPGAYLARDIINFGISELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQEMKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPNLPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDETSCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWRLGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNHTAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAAYYTQFDIEEWAKLNYGEDLFKFISKNTSPVDVLYKLANDYSVVLLSGNGFYGPEWSIRISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK
>CP029154.1|AWH81960.1|2814649_2814808_-|hypothetical-protein
MDNFLQGILASLSASLIVYVASKLFRKRKKPLKAATKSGWEFDLKIRFHKTK
>CP029154.1|AWH81961.1|2815165_2816536_-|cell-wall-binding-protein-Cwp29
MELKKLLSLGLAVSMFAAGPISANALDTIYTIQGKDKYETAALIADEQNYTTAILINTDSTMADGLSASGLAGATNAPILLTKKNNIPNATLKRVEKAKKVYIIGGESSIDKATETLLKDKGIEAKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAFKGEPDAMSAASVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMSDKLVNDTNSTRLGGVDRYDTNKKIVNKFYNGAKEFYITSGTDLVYALVASPMSKNNPIVLVDIGSNKDILKNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSKHIIWQDKGSYLECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDFNSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGEDFFEYK
>CP029154.1|AWH81962.1|2816934_2817357_+|hypothetical-protein
MTFVERCYKYIDMNKNNWSPYTVTNTKSWVKNYIEPFFKNLKLTEVNPSSVQAFVNYNFNNSTFTSAKVRYSFLSSVISEVYRLREIQENSCDFIKLPSKEKYSTNEIYNREEVLLLIEKLLGNNIEIPILLMLLLGLRM
>CP029154.1|AWH81963.1|2818342_2819011_-|VanZ-family-protein
METVSNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGISLIVIFKKDSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFSEYIRLSQLGETFFNPNISFIPFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHRATDINDLITNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALILGFFS
>CP029154.1|AWH81964.1|2819109_2819493_-|XRE-family-transcriptional-regulator
MSQKELAKKIGVSTSQLIKIISRKTRMVSSGILIGVADIFKFGLSEDIIKELVIGAVDVEILNRLMEHKNFQCLINLMRIYSQDMVDLGDMERNQFIDMVTIFLSNLMKESPKYYTEVRKELTDGIK
>CP029154.1|AWH81965.1|2819892_2822313_-|leucine--tRNA-ligase
MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYPSGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTMENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCPSCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKTMQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTEYEADVEAFVKKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYGTGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMIDSEEFNGLDASEGFEGIIDKLEKEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTGKGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKELVNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSKMSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLVDELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDMYKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKALVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPKKLVNVVVK
>CP029154.1|AWH81966.1|2822666_2823017_-|ribosome-silencing-factor
MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASSQRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEKLWKDAPYIDIDTLA
>CP029154.1|AWH81967.1|2823133_2823706_-|HDIG-domain-containing-protein
MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAYLAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDEDIINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFNNTLMFVINKKEEIHPRTVMARNYLIKEKLL
>CP029154.1|AWH81968.1|2823706_2824396_-|nicotinate-nucleotide-adenylyltransferase
MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAHLATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEIERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPGISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYLYENKLYQYGDD
>CP029154.1|AWH81969.1|2824671_2825310_+|regulatory-protein-RecX
MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNEINEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIVERVIDFLKSYNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTIDEAVSELDKDTEFENAMYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI

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Crispr_ID: CP029154_18

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029154_18

3760096-3760299

Orphan

Consensus_repeat	Method
TCATCATATAAACCTATTAAATATTATCTTATTTATTGGTATATGGAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029154_18

>merge|CP029154|18|3760096-3760299|CRISPRCasFinder
AATATAATCATTTCTCTTAAAGATTATCTTATTTATTACTATATGGAATCATATTGTTTATTATTTCATAGTCCTTTCATCATATAAACCTATTAAATATTATCTTATTTATTGGTATATGGAATTATTTTGTTTATTATTTTATAGTCTTTTCATCATCATATAAACCTATTAAATATTATCTTATTTATTGGTATATGGAAT

>CP029154|18|17|3760096-3760299|CRISPRCasFinder
AATATAATCATTTCTCTTAAAGATTATCTTATTTATTACTATATGGAAT	CATATTGTTTATTATTTCATAGTCCTTTCATCATATAAACCTATTAAATATTATCTTATTTATTGGTATATGGAATTATTTTGTTTATTATTTTATAGTCTTTTCA
TCATCATATAAACCTATTAAATATTATCTTATTTATTGGTATATGGAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP029154.1\|AWH82757.1\|3759226_3759982_+\|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl\|CDD\|234595
CP029154.1\|AWH82760.1\|3764647_3764797_+\|3-methyladenine-DNA-glycosylase	unknown	unknown	unknown
CP029154.1\|AWH82766.1\|3770917_3771400_-\|proline-reductase	unknown	unknown	gnl\|CDD\|275273
CP029154.1\|AWH82762.1\|3766833_3767403_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|225136
CP029154.1\|AWH82750.1\|3750783_3751977_-\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|273233
CP029154.1\|AWH82763.1\|3767586_3768222_-\|single-strand-DNA-binding-protein	unknown	unknown	gnl\|CDD\|235616
CP029154.1\|AWH82756.1\|3757797_3758787_-\|SPFH-domain-containing-protein	unknown	unknown	gnl\|CDD\|259800
CP029154.1\|AWH82758.1\|3760414_3762082_-\|collagen-like-protein	unknown	unknown	gnl\|CDD\|237537
CP029154.1\|AWH82752.1\|3753610_3754612_+\|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|237845
CP029154.1\|AWH82748.1\|3749083_3749338_-\|small,-acid-soluble-spore-protein,-alpha/beta-type	unknown	unknown	gnl\|CDD\|365990
CP029154.1\|AWH82765.1\|3769890_3770898_-\|proline-racemase	unknown	unknown	gnl\|CDD\|184427
CP029154.1\|AWH82761.1\|3764846_3766622_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226350
CP029154.1\|AWH82749.1\|3749459_3750578_-\|amidohydrolase	unknown	unknown	gnl\|CDD\|349920
CP029154.1\|AWH82753.1\|3754728_3755616_+\|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl\|CDD\|235107
CP029154.1\|AWH82755.1\|3756650_3757367_+\|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase	unknown	unknown	gnl\|CDD\|132571
CP029154.1\|AWH82764.1\|3768889_3769771_-\|permease	unknown	unknown	gnl\|CDD\|376667
CP029154.1\|AWH82759.1\|3762260_3762800_-\|hypoxanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|223707
CP029154.1\|AWH82754.1\|3755682_3756432_+\|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl\|CDD\|234595
CP029154.1\|AWH82751.1\|3752299_3753181_+\|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl\|CDD\|235107
CP029154.1\|AWH83358.1\|3763127_3764411_-\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206

Protein	Function_ID	Function_description	E-value
CP029154.1\|AWH82757.1\|3759226_3759982_+\|4-hydroxy-tetrahydrodipicolinate-reductase	gnl\|CDD\|234595	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional.	5.14787e-105
CP029154.1\|AWH82763.1\|3767586_3768222_-\|single-strand-DNA-binding-protein	gnl\|CDD\|235616	PRK05813, PRK05813, single-stranded DNA-binding protein; Provisional.	1.92637e-126
CP029154.1\|AWH82766.1\|3770917_3771400_-\|proline-reductase	gnl\|CDD\|275273	TIGR04480, D-proline_reductase_PrdA_proprotein, D-proline reductase (dithiol), PrdA proprotein. Members of this family are the PrdA proprotein. The polypeptide undergoes an autocatalytic cleavage that creates two subunits, one with a Cys-derived pyruvoyl motiety critical for activity. The D-proline reductase complex also contains a subunit derived from the prdB gene. The complex acts on D-proline, which may be supplied from L-proline by an active proline racemase encoded nearby.	1.72573e-32
CP029154.1\|AWH82762.1\|3766833_3767403_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	4.46184e-05
CP029154.1\|AWH82750.1\|3750783_3751977_-\|L-serine-ammonia-lyase	gnl\|CDD\|273233	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form. This enzyme is also called serine deaminase and L-serine dehydratase 1. L-serine ammonia-lyase converts serine into pyruvate in the gluconeogenesis pathway from serine. This enzyme is comprised of a single chain in Escherichia coli, Mycobacterium tuberculosis, and several other species, but has separate alpha and beta chains in Bacillus subtilis and related species. The beta and alpha chains are homologous to the N-terminal and C-terminal regions, respectively, but are rather deeply branched in a UPGMA tree. This enzyme requires iron and dithiothreitol for activation in vitro, and is a predicted 4Fe-4S protein. Escherichia coli Pseudomonas aeruginosa have two copies of this protein. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	6.67523e-139
CP029154.1\|AWH82756.1\|3757797_3758787_-\|SPFH-domain-containing-protein	gnl\|CDD\|259800	cd03402, SPFH_like_u2, Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model summarizes an uncharacterized family of proteins similar to stomatin, prohibitin, flotillin, HflK/C (SPFH) and podocin. The conserved domain common to the SPFH superfamily has also been referred to as the Band 7 domain. Many superfamily members are associated with lipid rafts. Individual proteins of the SPFH superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. Microdomains formed from flotillin proteins may in addition be dynamic units with their own regulatory functions. Flotillins have been implicated in signal transduction, vesicle trafficking, cytoskeleton rearrangement and are known to interact with a variety of proteins. Stomatin interacts with and regulates members of the degenerin/epithelia Na+ channel family in mechanosensory cells of Caenorhabditis elegans and vertebrate neurons and participates in trafficking of Glut1 glucose transporters. Prohibitin may act as a chaperone for the stabilization of mitochondrial proteins. Prokaryotic HflK/C plays a role in the decision between lysogenic and lytic cycle growth during lambda phage infection. Flotillins have been implicated in the progression of prion disease, in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's disease, and in cancer invasion and metastasis. Mutations in the podocin gene give rise to autosomal recessive steroid resistant nephritic syndrome.	4.28569e-128
CP029154.1\|AWH82758.1\|3760414_3762082_-\|collagen-like-protein	gnl\|CDD\|237537	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional.	3.53306e-06
CP029154.1\|AWH82752.1\|3753610_3754612_+\|aspartate-semialdehyde-dehydrogenase	gnl\|CDD\|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	0
CP029154.1\|AWH82748.1\|3749083_3749338_-\|small,-acid-soluble-spore-protein,-alpha/beta-type	gnl\|CDD\|365990	pfam00269, SASP, Small, acid-soluble spore proteins, alpha/beta type.	4.09426e-06
CP029154.1\|AWH82765.1\|3769890_3770898_-\|proline-racemase	gnl\|CDD\|184427	PRK13969, PRK13969, proline racemase; Provisional.	0
CP029154.1\|AWH82761.1\|3764846_3766622_-\|AAA-family-ATPase	gnl\|CDD\|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	2.0754e-152
CP029154.1\|AWH82749.1\|3749459_3750578_-\|amidohydrolase	gnl\|CDD\|349920	cd05670, M20_Acy1_YkuR-like, M20 Peptidase aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins. Peptidase M20 family, aminoacyclase-1 YkuR-like subfamily including YkuR and Ama/HipO/HyuC proteins, most of which have not been well characterized to date. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in the protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity; substrates include indoleacetic acid (IAA) N-conjugates of amino acids, N-acetyl-L-amino acids and aminobenzoylglutamate. ACY1 breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as in the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine). ACY1 appears to physically interact with Sphingosine kinase type 1 (SphK1) and may influence its physiological functions; SphK1 and its product sphingosine-1-phosphate have been shown to promote cell growth and inhibit apoptosis of tumor cells. Strong expression of the human gene and its mouse ortholog Acy1 in brain, liver, and kidney suggest a role of the enzyme in amino acid metabolism of these organs.	0
CP029154.1\|AWH82753.1\|3754728_3755616_+\|4-hydroxy-tetrahydrodipicolinate-synthase	gnl\|CDD\|235107	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional.	6.4792e-159
CP029154.1\|AWH82755.1\|3756650_3757367_+\|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase	gnl\|CDD\|132571	TIGR03532, DapD_Ac, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase. This enzyme is part of the diaminopimelate pathway of lysine biosynthesis. Alternate name: tetrahydrodipicolinate N-acetyltransferase. Note that IUBMB lists this alternate name as the accepted name. Unfortunately, the related succinyl transferase acting on the same substrate (EC:2.3.1.117, TIGR00695) uses the opposite standard. We have decided to give these two enzymes names which more clearly indicated that they act on the same substrate.	2.92516e-110
CP029154.1\|AWH82764.1\|3768889_3769771_-\|permease	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	4.23857e-08
CP029154.1\|AWH82759.1\|3762260_3762800_-\|hypoxanthine-phosphoribosyltransferase	gnl\|CDD\|223707	COG0634, Hpt, Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism].	6.46308e-76
CP029154.1\|AWH82754.1\|3755682_3756432_+\|4-hydroxy-tetrahydrodipicolinate-reductase	gnl\|CDD\|234595	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional.	8.73789e-105
CP029154.1\|AWH82751.1\|3752299_3753181_+\|4-hydroxy-tetrahydrodipicolinate-synthase	gnl\|CDD\|235107	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional.	8.07763e-154
CP029154.1\|AWH83358.1\|3763127_3764411_-\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	2.15127e-105

>CP029154.1|AWH82757.1|3759226_3759982_+|4-hydroxy-tetrahydrodipicolinate-reductase
MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHSDTKLYKTMTDVTEKADVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLHKIEEASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIANAIKEVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLNHHSQSDEVFANGSIIAAKFLIGKQSGLYKMSDILG
>CP029154.1|AWH82756.1|3757797_3758787_-|SPFH-domain-containing-protein
MLKEEKTYQEKEAKVFNGVAALIMIVLFLVVSIGIMVFGIVKLDSGFTGIGSLMLILGLIFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVNPFCSAINPAASRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPIIIGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSSQEIADRLKDELQSRVDIAGIEVSEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVEGAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY
>CP029154.1|AWH82755.1|3756650_3757367_+|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase
MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFGSNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIRDMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLEPPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIKMKDEKTADKTKLMEDLRNLD
>CP029154.1|AWH82754.1|3755682_3756432_+|4-hydroxy-tetrahydrodipicolinate-reductase
MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDLKIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIHEAAKVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANAIKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQSRGIFASGSIAAAKYLVKQKPGFYNMDSMLG
>CP029154.1|AWH82753.1|3754728_3755616_+|4-hydroxy-tetrahydrodipicolinate-synthase
MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCGTTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALLIITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVAVKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDLVAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDPANLEVLKKELVNFGLKVNA
>CP029154.1|AWH82752.1|3753610_3754612_+|aspartate-semialdehyde-dehydrogenase
MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGSKVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWRMNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRIVYSTYQAVSGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKILDNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEYPTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV
>CP029154.1|AWH82751.1|3752299_3753181_+|4-hydroxy-tetrahydrodipicolinate-synthase
MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCGTTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLLIITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVAVKEASGDLAQVAEIAKLVPKDFTIYSGNDDTILPLLSLGGSGVISVLANICPKETHDLVTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEETNLNVLKQELTNSGFKF
>CP029154.1|AWH82750.1|3750783_3751977_-|L-serine-ammonia-lyase
MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILYGSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWTVYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYIKTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQNASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASISGAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIPCIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAKHFFSC
>CP029154.1|AWH82749.1|3749459_3750578_-|amidohydrolase
MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGIEYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYLNDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGTREGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAVLTIGRIEGGARRNIIAENIKMEGTMRCFNPEVYEKMKLRVRELARGFGLAYNCKVNINIIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNEEKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID
>CP029154.1|AWH82748.1|3749083_3749338_-|small,-acid-soluble-spore-protein,-alpha/beta-type
MIFLKEKIQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERGWAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI
>CP029154.1|AWH82758.1|3760414_3762082_-|collagen-like-protein
MSDISGPSLYQDIGPTGPTGPTGPTGPRGATGATGANGITGPTGNTGATGANGITGPTGNMGATGANGTTGSTGPTGNTGATGANGITGPTGATGATGANGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGATGLTGATGATGANGITGPTGNTGATGANGVTGATGPIGNTGATGSTGSIGATGANGVTGATGPIGATGPTGADGEVGPTGAVGATGPDGAIGPTGNTGATGATGANGLVGPTGATGATGANGLVGPTGPTGATGPDGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGATGANGAAGPIGPTGPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTGATGANGATGATGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLGNNTLLTFNSSFINGTNITFPTSSTINLAVGGIYNVSFGIRAILSLAGFMSITTNFNGVAQNNFIAKAVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSPAGYVSVYRIQ
>CP029154.1|AWH82759.1|3762260_3762800_-|hypoxanthine-phosphoribosyltransferase
MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLKGSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGRVKVVSDVTTDIAGYDVLVVDDITDSAFTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFDFGDYYRNVPYIFNVTDEDR
>CP029154.1|AWH83358.1|3763127_3764411_-|serine-dehydratase-subunit-alpha-family-protein
MEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIVENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIAEDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNEPKVSASNDVAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQKTGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTAILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGISWLMNGTENQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVPPLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD
>CP029154.1|AWH82760.1|3764647_3764797_+|3-methyladenine-DNA-glycosylase
MTISQKDKKKSQNEILYHFETAQTYYFLIYKNHFLIHKKRLCKTLIAEV
>CP029154.1|AWH82761.1|3764846_3766622_-|AAA-family-ATPase
MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGVYIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICDGDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKLETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFKKDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIKLENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIAVNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSKLLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLPSLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYSVNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDKELTAKALGISRATLYRKIEKYNIIS
>CP029154.1|AWH82762.1|3766833_3767403_-|methyltransferase-domain-containing-protein
MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIGNLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVDQFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHEVFNIFSRLNFDGMIKESNKLKYIYVGKRR
>CP029154.1|AWH82763.1|3767586_3768222_-|single-strand-DNA-binding-protein
MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSDSFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDEENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFAKNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE
>CP029154.1|AWH82764.1|3768889_3769771_-|permease
MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVTGFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIPVDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLPGGGNELGLTGAKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGSCALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIAYTSATMIMAANKNKKTA
>CP029154.1|AWH82765.1|3769890_3770898_-|proline-racemase
MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEENLDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAAIETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPGVGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLAHIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGEKFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFILK
>CP029154.1|AWH82766.1|3770917_3771400_-|proline-reductase
MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSEHNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIMGADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK

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Crispr_ID: CP029154_20

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029154_20

4147950-4148084

Orphan

Consensus_repeat	Method
GTTGCTTAAAGTGCTAACGCACAGCGCCAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029154_20

>merge|CP029154|20|4147950-4148084|CRISPRCasFinder
AGTTTTCAAAGTGCTAACGCACAGCGCCAACGGATAAATCCCGTTGCTTAAAGTGCTAACGCACAGCGCCAACAAACAAACTTCACATGCGTTCAGTTTATTCTGTTGCTTAAAGTACTAACGCACAGCGCCAAC

>CP029154|20|18|4147950-4148084|CRISPRCasFinder
AGTTTTCAAAGTGCTAACGCACAGCGCCAAC	GGATAAATCCCGTTGCTTAAAGTGCTAACGCACAGCGCCAACAAACAAACTTCACATGCGTTCAGTTTATTCT
GTTGCTTAAAGTACTAACGCACAGCGCCAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP029154.1\|AWH83115.1\|4154495_4155086_-\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|227029
CP029154.1\|AWH83116.1\|4155268_4156237_-\|peptidase-S58-family-protein	unknown	unknown	gnl\|CDD\|239070
CP029154.1\|AWH83106.1\|4141080_4142016_-\|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl\|CDD\|180132
CP029154.1\|AWH83113.1\|4152601_4153570_-\|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl\|CDD\|129820
CP029154.1\|AWH83119.1\|4159532_4160921_-\|tRNA(Ile)-lysidine-synthetase	unknown	unknown	gnl\|CDD\|274129
CP029154.1\|AWH83105.1\|4140190_4141084_-\|stage-0-sporulation-protein	unknown	unknown	gnl\|CDD\|224688
CP029154.1\|AWH83108.1\|4142828_4144238_-\|arginine-decarboxylase	unknown	unknown	gnl\|CDD\|224893
CP029154.1\|AWH83111.1\|4150469_4151999_-\|lysine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234778
CP029154.1\|AWH83104.1\|4139366_4140113_-\|tRNA1(Val)-(adenine(37)-N6)-methyltransferase	unknown	unknown	gnl\|CDD\|226608
CP029154.1\|AWH83103.1\|4138532_4139366_-\|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	unknown	unknown	gnl\|CDD\|381175
CP029154.1\|AWH83109.1\|4144392_4144584_-\|DUF378-domain-containing-protein	unknown	unknown	gnl\|CDD\|377214
CP029154.1\|AWH83101.1\|4137189_4137618_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
CP029154.1\|AWH83100.1\|4135722_4137153_+\|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|236426
CP029154.1\|AWH83118.1\|4157528_4159523_-\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl\|CDD\|273520
CP029154.1\|AWH83102.1\|4137805_4138510_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|131739
CP029154.1\|AWH83112.1\|4152013_4152493_-\|transcription-elongation-factor-GreA	unknown	unknown	gnl\|CDD\|234693
CP029154.1\|AWH83110.1\|4149966_4150248_-\|hypothetical-protein	unknown	unknown	unknown
CP029154.1\|AWH83107.1\|4142018_4142708_-\|thymidylate-kinase	unknown	unknown	gnl\|CDD\|223203
CP029154.1\|AWH83117.1\|4156229_4157207_-\|biotin--[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl\|CDD\|237010
CP029154.1\|AWH83114.1\|4153706_4154477_-\|type-III-pantothenate-kinase	unknown	unknown	gnl\|CDD\|237347

Protein	Function_ID	Function_description	E-value
CP029154.1\|AWH83115.1\|4154495_4155086_-\|ECF-transporter-S-component	gnl\|CDD\|227029	COG4684, COG4684, Predicted membrane protein [Function unknown].	2.89958e-30
CP029154.1\|AWH83116.1\|4155268_4156237_-\|peptidase-S58-family-protein	gnl\|CDD\|239070	cd02252, nylC_like, nylC-like family; composed of proteins with similarity to Flavobacterium endo-type 6-aminohexanoate-oligomer hydrolase (EIII), the product of the nylon oligomer degradation gene, nylC. EIII is an amide hydrolase that catalyzes the degradation of highly-polymerized 6-aminohexanoate oligomers. Together with other nylon degradation enzymes, such as 6-aminohexanoate cyclic dimer hydrolase (EI) and 6-aminohexanoate dimer hydrolase (EII), EIII plays a role in the detoxification and biological removal of the synthetic by-products of nylon manufacture. EIII shows sequence similarity to L-aminopeptidase D-amidase/D-esterase (DmpA), an aminopeptidase that releases N-terminal D and L amino acids from peptide substrates. Like DmpA, EIII undergoes autocatalytic cleavage in front of a nucleophile to form a heterodimer. DmpA shows similarity in catalytic mechanism to N-terminal nucleophile (Ntn) hydrolases, which are enzymes that catalyze the cleavage of amide bonds through the nucleophilic attack of the side chain of an N-terminal serine, threonine, or cysteine.	4.12483e-125
CP029154.1\|AWH83106.1\|4141080_4142016_-\|DNA-polymerase-III-subunit-delta'	gnl\|CDD\|180132	PRK05564, PRK05564, DNA polymerase III subunit delta'; Validated.	2.48099e-57
CP029154.1\|AWH83113.1\|4152601_4153570_-\|tRNA-dihydrouridine-synthase-DusB	gnl\|CDD\|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	1.20917e-153
CP029154.1\|AWH83119.1\|4159532_4160921_-\|tRNA(Ile)-lysidine-synthetase	gnl\|CDD\|274129	TIGR02432, tRNAIle-lysidine_synthase, tRNA(Ile)-lysidine synthetase, N-terminal domain. The only examples in which the wobble position of a tRNA must discriminate between G and A of mRNA are AUA (Ile) vs. AUG (Met) and UGA (stop) vs. UGG (Trp). In all bacteria, the wobble position of the tRNA(Ile) recognizing AUA is lysidine, a lysine derivative of cytidine. This family describes a protein domain found, apparently, in all bacteria in a single copy. Eukaryotic sequences appear to be organellar. The domain archictecture of this protein family is variable; some, including characterized proteins of E. coli and B. subtilis known to be tRNA(Ile)-lysidine synthetase, include a conserved 50-residue domain that many other members lack. This protein belongs to the ATP-binding PP-loop family ( pfam01171). It appears in the literature and protein databases as TilS, YacA, and putative cell cycle protein MesJ (a misnomer). [Protein synthesis, tRNA and rRNA base modification].	9.7353e-71
CP029154.1\|AWH83105.1\|4140190_4141084_-\|stage-0-sporulation-protein	gnl\|CDD\|224688	COG1774, COG1774, Uncharacterized homolog of PSP1 [Function unknown].	2.232e-96
CP029154.1\|AWH83108.1\|4142828_4144238_-\|arginine-decarboxylase	gnl\|CDD\|224893	COG1982, LdcC, Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism].	6.30397e-121
CP029154.1\|AWH83100.1\|4135722_4137153_+\|nicotinate-phosphoribosyltransferase	gnl\|CDD\|236426	PRK09243, PRK09243, nicotinate phosphoribosyltransferase; Validated.	0
CP029154.1\|AWH83104.1\|4139366_4140113_-\|tRNA1(Val)-(adenine(37)-N6)-methyltransferase	gnl\|CDD\|226608	COG4123, COG4123, Predicted O-methyltransferase [General function prediction only].	9.15081e-98
CP029154.1\|AWH83103.1\|4138532_4139366_-\|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	gnl\|CDD\|381175	cd11648, RsmI, Ribosomal RNA small subunit methyltransferase I (RsmI), also known as rRNA (cytidine-2'-O-)-methyltransferase. RsmI is an S-AdoMet (S-adenosyl-L-methionine or SAM)-dependent methyltransferase responsible for the 2'-O-methylation of cytidine 1402 (C1402) at the P site of bacterial 16S rRNA. Another S-AdoMet-dependent methyltransferase, RsmH (not included in this family), is responsible for N4-methylation at C1402. These methylation reactions may occur at a late step during 30S assembly in the cell. The dimethyl modification is believed to be conserved in bacteria, may play a role in fine-tuning the shape and functions of the P-site to increase the translation fidelity, and has been shown for Staphylococcus aureus, to contribute to virulence in host animals by conferring resistance to oxidative stress.	2.47321e-128
CP029154.1\|AWH83109.1\|4144392_4144584_-\|DUF378-domain-containing-protein	gnl\|CDD\|377214	pfam04070, DUF378, Domain of unknown function (DUF378). Predicted transmembrane domain of unknown function. The majority of the family have two predicted transmembrane regions.	4.45287e-17
CP029154.1\|AWH83101.1\|4137189_4137618_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	5.08799e-36
CP029154.1\|AWH83111.1\|4150469_4151999_-\|lysine--tRNA-ligase	gnl\|CDD\|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
CP029154.1\|AWH83118.1\|4157528_4159523_-\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl\|CDD\|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
CP029154.1\|AWH83102.1\|4137805_4138510_-\|HD-domain-containing-protein	gnl\|CDD\|131739	TIGR02692, putative_tRNA_nucleotidyltransferase, tRNA adenylyltransferase. The enzyme tRNA adenylyltransferase, also called tRNA-nucleotidyltransferase and CCA-adding enzyme, can add or repair the required CCA triplet at the 3'-end of tRNA molecules. Genes encoding tRNA include the CCA tail in some but not all bacteria, and this enzyme may be required for viability. Members of this family represent a distinct clade within the larger family pfam01743 (tRNA nucleotidyltransferase/poly(A) polymerase family protein). The example from Streptomyces coelicolor was shown to act as a CCA-adding enzyme and not as a poly(A) polymerase. [Protein synthesis, tRNA and rRNA base modification].	3.07027e-09
CP029154.1\|AWH83112.1\|4152013_4152493_-\|transcription-elongation-factor-GreA	gnl\|CDD\|234693	PRK00226, greA, transcription elongation factor GreA; Reviewed.	2.99301e-69
CP029154.1\|AWH83107.1\|4142018_4142708_-\|thymidylate-kinase	gnl\|CDD\|223203	COG0125, Tmk, Thymidylate kinase [Nucleotide transport and metabolism].	4.17093e-36
CP029154.1\|AWH83117.1\|4156229_4157207_-\|biotin--[acetyl-CoA-carboxylase]-ligase	gnl\|CDD\|237010	PRK11886, PRK11886, bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA.	1.2418e-73
CP029154.1\|AWH83114.1\|4153706_4154477_-\|type-III-pantothenate-kinase	gnl\|CDD\|237347	PRK13318, PRK13318, type III pantothenate kinase.	3.53007e-154

>CP029154.1|AWH83109.1|4144392_4144584_-|DUF378-domain-containing-protein
MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYFIVGLAGLYLIPSLMSDDRE
>CP029154.1|AWH83108.1|4142828_4144238_-|arginine-decarboxylase
MFIINELNKIVNEEVISFHMPGHKKGQIYKKLGYKDILENLYKMDTTEILGTDNLHFPEGIIKNSQEKASRVFKSDYTCYLVNGSSCGIQSAIMSVCRPKSKIITNRDCHQSVINGCILGDIDIEYVPCEVSEETNVLKGISISNVIDIVDKNLDAKAVLLTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQSTHKTLPSFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGKELMEELLNNIRTFKNNVDSNINIYDTNDKTKIFISSKNMGLTGYELESILRNKYNIQVELSNYYGVLLICTIGNTAKDFSSLETALNNVIKEDFKFEKLENKKYPVVIPKKILTPREAFYKTKKSVKIYDSIGKICGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIVSGLKDVDLNFIQVIDLEDI
>CP029154.1|AWH83107.1|4142018_4142708_-|thymidylate-kinase
MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYESPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRYTTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPKPDCVIFLDVPIEFSEKLMENRKNKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYKIVLDSIKSMER
>CP029154.1|AWH83106.1|4141080_4142016_-|DNA-polymerase-III-subunit-delta'
MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFADELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEKMTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLINTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIPNNMEKYRGKIIALLDMMINYFRDIIILKENVNKNMLINVDKLVFIQNMSGKISYSQLSKIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK
>CP029154.1|AWH83105.1|4140190_4141084_-|stage-0-sporulation-protein
MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKVVVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFLIDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGPCGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEKMPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGGKCKDNDGLDEATLRELKKLED
>CP029154.1|AWH83104.1|4139366_4140113_-|tRNA1(Val)-(adenine(37)-N6)-methyltransferase
MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKDAKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSVKLNGLEERVKIINEDIKYIDKVLDVNGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVMPRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELKILDPLYVYGEDGNYTKELKAIYNNKDIGEL
>CP029154.1|AWH83103.1|4138532_4139366_-|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase
MSGKLYICPTPIGNLEDITYRTLRILKEVDLIAAEDTRHSIKLLNHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQNNIEIEVLPGATAFVTALVGSGMDTHKFVFEGFLDRDKKVRKAQLEELKEESRTIIFYESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVLIVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLDL
>CP029154.1|AWH83102.1|4137805_4138510_-|HD-domain-containing-protein
MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGECKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYTEKGINKLHVLKLGTFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHMILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYMEYILTNYLYKSNYTHV
>CP029154.1|AWH83101.1|4137189_4137618_+|Lrp/AsnC-family-transcriptional-regulator
MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEESGVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLLLKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL
>CP029154.1|AWH83100.1|4135722_4137153_+|nicotinate-phosphoribosyltransferase
MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGYTIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIMFPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQGPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADVYPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLDNAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASCEKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFHPTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSKPHIYKVDLSRNLWYLKTQMIDSKKVL
>CP029154.1|AWH83110.1|4149966_4150248_-|hypothetical-protein
MKIFRIIYEKVKRIIYENTIYKKLLGECLMFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSINVWADRVRANSYSYENKIAK
>CP029154.1|AWH83111.1|4150469_4151999_-|lysine--tRNA-ligase
MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRYDRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIGEEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQELRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARPFITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIELYQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSGVDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEVSPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAFEMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKDEEN
>CP029154.1|AWH83112.1|4152013_4152493_-|transcription-elongation-factor-GreA
MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGDLSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFDEEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR
>CP029154.1|AWH83113.1|4152601_4153570_-|tRNA-dihydrouridine-synthase-DusB
MKIGNLKLKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMINGKALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPAPKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAEDCGISALAIHGRTREQFYSGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGCDAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAVREMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT
>CP029154.1|AWH83114.1|4153706_4154477_-|type-III-pantothenate-kinase
MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILISNLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDNPKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEALFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKVIATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE
>CP029154.1|AWH83115.1|4154495_4155086_-|ECF-transporter-S-component
MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKATIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMIGVLAYYVYQLIIKATNKVYMSGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGSAGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK
>CP029154.1|AWH83116.1|4155268_4156237_-|peptidase-S58-family-protein
MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSAPGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIVVGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMKGGIGSYSIKLDNGLVVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGESKGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKAIFPIHTPHDGDTIFTISTGEIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIIKKREI
>CP029154.1|AWH83117.1|4156229_4157207_-|biotin--[acetyl-CoA-carboxylase]-ligase
MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEGYNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLETIDSTNEHAKRTAINSVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVTKALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYIVLGIGINVKIMDFEQEIADKATSLYKEGYMLPRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKNIYVLKGDNKELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV
>CP029154.1|AWH83118.1|4157528_4159523_-|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MYERRASILNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYRELTDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGEAKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRVTFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLGGGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPDVKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIKMETIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPRGRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTATARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYDKTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEIEEQLTIKLEKDEEERNNVIDINKNLEDKSDKDK
>CP029154.1|AWH83119.1|4159532_4160921_-|tRNA(Ile)-lysidine-synthetase
MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKKDFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIVFFVKSINVPKYCENEGLSLEEGARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNCIIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIESIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNSIKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEEIEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSRRQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDENTKEVLKINFNKL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP029154_1	1.1\|32118\|31\|CP029154\|CRISPRCasFinder	32118-32148	31	CP029154.1	17782-17812	0	1.0
CP029154_1	1.1\|32118\|31\|CP029154\|CRISPRCasFinder	32118-32148	31	CP029154.1	1171645-1171675	0	1.0
CP029154_7	7.9\|1688962\|36\|CP029154\|CRISPRCasFinder,CRT	1688962-1688997	36	CP029154.1	3030623-3030658	1	0.972
CP029154_20	20.1\|4147981\|73\|CP029154\|CRISPRCasFinder	4147981-4148053	73	CP029154.1	32118-32190	13	0.822
CP029154_20	20.1\|4147981\|73\|CP029154\|CRISPRCasFinder	4147981-4148053	73	CP029154.1	1171645-1171717	13	0.822

1. spacer 1.1|32118|31|CP029154|CRISPRCasFinder matches to position: 17782-17812, mismatch: 0, identity: 1.0

agaataaactgaacgcatgtgaagtttgttt	CRISPR spacer
agaataaactgaacgcatgtgaagtttgttt	Protospacer
*******************************

2. spacer 1.1|32118|31|CP029154|CRISPRCasFinder matches to position: 1171645-1171675, mismatch: 0, identity: 1.0

agaataaactgaacgcatgtgaagtttgttt	CRISPR spacer
agaataaactgaacgcatgtgaagtttgttt	Protospacer
*******************************

3. spacer 7.9|1688962|36|CP029154|CRISPRCasFinder,CRT matches to position: 3030623-3030658, mismatch: 1, identity: 0.972

tatatattagatgtcaatgtcaaggatacaaaattt	CRISPR spacer
tatatattagatgtcaatatcaaggatacaaaattt	Protospacer
******************.*****************

4. spacer 20.1|4147981|73|CP029154|CRISPRCasFinder matches to position: 32118-32190, mismatch: 13, identity: 0.822

ggataaatcccgttgcttaaagtgctaacgcacagcgccaacaaacaaacttcacatgcg	CRISPR spacer
ggataaatcccgttgcttaaagtgctaacgcacagcgccaacaaacaaacttcacatgcg	Protospacer
************************************************************

5. spacer 20.1|4147981|73|CP029154|CRISPRCasFinder matches to position: 1171645-1171717, mismatch: 13, identity: 0.822

ggataaatcccgttgcttaaagtgctaacgcacagcgccaacaaacaaacttcacatgcg	CRISPR spacer
ggataaatcccgttgcttaaagtgctaacgcacagcgccaacaaacaaacttcacatgcg	Protospacer
************************************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP029154_6	6.1\|1579028\|25\|CP029154\|PILER-CR	1579028-1579052	25	NZ_MF547664	Clostridioides difficile strain LIBA-6289 plasmid LIBA6289, complete sequence	50448-50472	0	1.0
CP029154_6	6.3\|1579017\|36\|CP029154\|CRISPRCasFinder,CRT	1579017-1579052	36	NZ_MF547664	Clostridioides difficile strain LIBA-6289 plasmid LIBA6289, complete sequence	50447-50482	0	1.0
CP029154_7	7.4\|1688635\|36\|CP029154\|CRISPRCasFinder,CRT	1688635-1688670	36	NC_011398	Clostridium phage phiCD27, complete genome	22207-22242	0	1.0
CP029154_7	7.5\|1688700\|37\|CP029154\|CRISPRCasFinder,CRT	1688700-1688736	37	HG531805	Clostridium phage CDMH1 complete genome	45157-45193	0	1.0
CP029154_9	9.2\|1782864\|37\|CP029154\|CRT	1782864-1782900	37	HG531805	Clostridium phage CDMH1 complete genome	13828-13864	0	1.0
CP029154_9	9.3\|1782930\|36\|CP029154\|CRT	1782930-1782965	36	LN681542	Clostridium phage phiMMP03, complete genome	14215-14250	0	1.0
CP029154_9	9.3\|1782930\|36\|CP029154\|CRT	1782930-1782965	36	NC_009231	Clostridium phage phiC2, complete genome	14246-14281	0	1.0
CP029154_9	9.3\|1782930\|36\|CP029154\|CRT	1782930-1782965	36	LN681541	Clostridium phage phiMMP01, complete genome	14215-14250	0	1.0
CP029154_10	10.2\|1924261\|36\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924261-1924296	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	3114-3149	0	1.0
CP029154_10	10.2\|1924261\|36\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924261-1924296	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	118851-118886	0	1.0
CP029154_10	10.2\|1924261\|36\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924261-1924296	36	LN681537	Clostridium phage phiCD211, complete genome	127713-127748	0	1.0
CP029154_12	12.7\|2814301\|34\|CP029154\|PILER-CR	2814301-2814334	34	NC_048642	Clostridium phage CDKM9, complete genome	18002-18035	0	1.0
CP029154_1	1.1\|32118\|31\|CP029154\|CRISPRCasFinder	32118-32148	31	NZ_CP033215	Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence	3094-3124	1	0.968
CP029154_7	7.2\|1688502\|37\|CP029154\|CRISPRCasFinder,CRT	1688502-1688538	37	HM568888	Clostridium phage phiCD38-2, complete genome	1916-1952	1	0.973
CP029154_7	7.9\|1688962\|36\|CP029154\|CRISPRCasFinder,CRT	1688962-1688997	36	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	20150-20185	1	0.972
CP029154_7	7.9\|1688962\|36\|CP029154\|CRISPRCasFinder,CRT	1688962-1688997	36	NC_007917	Clostridium phage phi CD119, complete genome	20150-20185	1	0.972
CP029154_7	7.9\|1688962\|36\|CP029154\|CRISPRCasFinder,CRT	1688962-1688997	36	NC_028996	Clostridium phage phiCDHM19, complete genome	20404-20439	1	0.972
CP029154_7	7.9\|1688962\|36\|CP029154\|CRISPRCasFinder,CRT	1688962-1688997	36	NC_028838	Clostridium phage phiCD506, complete genome	13735-13770	1	0.972
CP029154_7	7.9\|1688962\|36\|CP029154\|CRISPRCasFinder,CRT	1688962-1688997	36	LN681538	Clostridium phage phiCD481-1, complete genome	13762-13797	1	0.972
CP029154_8	8.1\|1779904\|37\|CP029154\|PILER-CR,CRT	1779904-1779940	37	LN681542	Clostridium phage phiMMP03, complete genome	16005-16041	1	0.973
CP029154_8	8.1\|1779904\|37\|CP029154\|PILER-CR,CRT	1779904-1779940	37	NC_009231	Clostridium phage phiC2, complete genome	16036-16072	1	0.973
CP029154_8	8.1\|1779904\|37\|CP029154\|PILER-CR,CRT	1779904-1779940	37	LN681541	Clostridium phage phiMMP01, complete genome	16005-16041	1	0.973
CP029154_9	9.5\|1782864\|38\|CP029154\|CRISPRCasFinder	1782864-1782901	38	HG531805	Clostridium phage CDMH1 complete genome	13828-13865	1	0.974
CP029154_9	9.6\|1782930\|37\|CP029154\|CRISPRCasFinder	1782930-1782966	37	LN681542	Clostridium phage phiMMP03, complete genome	14215-14251	1	0.973
CP029154_9	9.6\|1782930\|37\|CP029154\|CRISPRCasFinder	1782930-1782966	37	NC_009231	Clostridium phage phiC2, complete genome	14246-14282	1	0.973
CP029154_9	9.6\|1782930\|37\|CP029154\|CRISPRCasFinder	1782930-1782966	37	LN681541	Clostridium phage phiMMP01, complete genome	14215-14251	1	0.973
CP029154_9	9.8\|1782866\|38\|CP029154\|PILER-CR	1782866-1782903	38	HG531805	Clostridium phage CDMH1 complete genome	13828-13865	1	0.974
CP029154_10	10.3\|1924326\|35\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924326-1924360	35	MK473382	Clostridium phage JD032, complete genome	7166-7200	1	0.971
CP029154_10	10.5\|1924455\|36\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924455-1924490	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	76310-76345	1	0.972
CP029154_10	10.5\|1924455\|36\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924455-1924490	36	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	97862-97897	1	0.972
CP029154_10	10.5\|1924455\|36\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924455-1924490	36	MF547662	Clostridioides phage LIBA6276, complete genome	51715-51750	1	0.972
CP029154_10	10.5\|1924455\|36\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924455-1924490	36	MF547663	Clostridioides phage LIBA2945, complete genome	51565-51600	1	0.972
CP029154_10	10.5\|1924455\|36\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924455-1924490	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	45655-45690	1	0.972
CP029154_10	10.5\|1924455\|36\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924455-1924490	36	LN681537	Clostridium phage phiCD211, complete genome	54517-54552	1	0.972
CP029154_12	12.7\|2814301\|34\|CP029154\|PILER-CR	2814301-2814334	34	LN681539	Clostridium phage phiCD505, complete genome	18064-18097	1	0.971
CP029154_12	12.7\|2814301\|34\|CP029154\|PILER-CR	2814301-2814334	34	JX145341	Clostridium phage phiMMP02, complete genome	17970-18003	1	0.971
CP029154_19	19.7\|3761261\|21\|CP029154\|CRT	3761261-3761281	21	MN480762	Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence	176923-176943	1	0.952
CP029154_19	19.8\|3761306\|21\|CP029154\|CRT	3761306-3761326	21	MN480762	Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence	176923-176943	1	0.952
CP029154_7	7.2\|1688502\|37\|CP029154\|CRISPRCasFinder,CRT	1688502-1688538	37	KU057941	Clostridium phage CDSH1, complete genome	1888-1924	2	0.946
CP029154_7	7.2\|1688502\|37\|CP029154\|CRISPRCasFinder,CRT	1688502-1688538	37	NC_028905	Clostridium phage phiCD111, complete genome	1916-1952	2	0.946
CP029154_7	7.2\|1688502\|37\|CP029154\|CRISPRCasFinder,CRT	1688502-1688538	37	LN881738	Escherichia phage slur17, complete genome	18513-18549	2	0.946
CP029154_7	7.3\|1688568\|38\|CP029154\|CRISPRCasFinder,CRT	1688568-1688605	38	NC_048665	Clostridium phage phiCDHM14, complete genome	23559-23596	2	0.947
CP029154_7	7.3\|1688568\|38\|CP029154\|CRISPRCasFinder,CRT	1688568-1688605	38	HG796225	Clostridium phage phiCDHM13 complete genome	23060-23097	2	0.947
CP029154_7	7.3\|1688568\|38\|CP029154\|CRISPRCasFinder,CRT	1688568-1688605	38	LN681538	Clostridium phage phiCD481-1, complete genome	22799-22836	2	0.947
CP029154_7	7.3\|1688568\|38\|CP029154\|CRISPRCasFinder,CRT	1688568-1688605	38	HG798901	Clostridium phage phiCDHM11 complete genome	23059-23096	2	0.947
CP029154_7	7.6\|1688766\|37\|CP029154\|CRISPRCasFinder,CRT	1688766-1688802	37	GU949551	Clostridium phage phiCD6356, complete genome	27126-27162	2	0.946
CP029154_7	7.9\|1688962\|36\|CP029154\|CRISPRCasFinder,CRT	1688962-1688997	36	NC_048665	Clostridium phage phiCDHM14, complete genome	13309-13344	2	0.944
CP029154_7	7.9\|1688962\|36\|CP029154\|CRISPRCasFinder,CRT	1688962-1688997	36	MK473382	Clostridium phage JD032, complete genome	21368-21403	2	0.944
CP029154_7	7.9\|1688962\|36\|CP029154\|CRISPRCasFinder,CRT	1688962-1688997	36	HG796225	Clostridium phage phiCDHM13 complete genome	13277-13312	2	0.944
CP029154_7	7.9\|1688962\|36\|CP029154\|CRISPRCasFinder,CRT	1688962-1688997	36	HG798901	Clostridium phage phiCDHM11 complete genome	13276-13311	2	0.944
CP029154_7	7.10\|1689027\|38\|CP029154\|CRISPRCasFinder,CRT	1689027-1689064	38	NZ_MG973074	Clostridioides difficile strain HSJD-312 plasmid pHSJD-312, complete sequence	94861-94898	2	0.947
CP029154_8	8.1\|1779904\|37\|CP029154\|PILER-CR,CRT	1779904-1779940	37	HG531805	Clostridium phage CDMH1 complete genome	17198-17234	2	0.946
CP029154_8	8.4\|1779903\|38\|CP029154\|CRISPRCasFinder	1779903-1779940	38	LN681542	Clostridium phage phiMMP03, complete genome	16005-16042	2	0.947
CP029154_8	8.4\|1779903\|38\|CP029154\|CRISPRCasFinder	1779903-1779940	38	NC_009231	Clostridium phage phiC2, complete genome	16036-16073	2	0.947
CP029154_8	8.4\|1779903\|38\|CP029154\|CRISPRCasFinder	1779903-1779940	38	LN681541	Clostridium phage phiMMP01, complete genome	16005-16042	2	0.947
CP029154_10	10.1\|1924196\|36\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924196-1924231	36	MF547663	Clostridioides phage LIBA2945, complete genome	118698-118733	2	0.944
CP029154_10	10.1\|1924196\|36\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924196-1924231	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	117743-117778	2	0.944
CP029154_10	10.1\|1924196\|36\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924196-1924231	36	LN681537	Clostridium phage phiCD211, complete genome	126605-126640	2	0.944
CP029154_10	10.1\|1924196\|36\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924196-1924231	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	4222-4257	2	0.944
CP029154_10	10.6\|1924520\|38\|CP029154\|PILER-CR,CRISPRCasFinder,CRT	1924520-1924557	38	NZ_MF547664	Clostridioides difficile strain LIBA-6289 plasmid LIBA6289, complete sequence	26432-26469	2	0.947
CP029154_12	12.7\|2814301\|34\|CP029154\|PILER-CR	2814301-2814334	34	KX228400	Clostridium phage CDKM15, complete genome	21207-21240	2	0.941
CP029154_7	7.2\|1688502\|37\|CP029154\|CRISPRCasFinder,CRT	1688502-1688538	37	NC_028958	Clostridium phage phiCD146, complete genome	1921-1957	3	0.919
CP029154_8	8.2\|1779970\|36\|CP029154\|PILER-CR,CRT	1779970-1780005	36	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	17906-17941	3	0.917
CP029154_8	8.4\|1779903\|38\|CP029154\|CRISPRCasFinder	1779903-1779940	38	HG531805	Clostridium phage CDMH1 complete genome	17198-17235	3	0.921
CP029154_12	12.4\|2814300\|42\|CP029154\|CRT	2814300-2814341	42	NC_048642	Clostridium phage CDKM9, complete genome	18001-18042	3	0.929
CP029154_4	4.1\|811203\|33\|CP029154\|CRISPRCasFinder	811203-811235	33	NZ_MG205641	Paeniclostridium sordellii strain 7508-A plasmid pCS1-7, complete sequence	15023-15055	4	0.879
CP029154_4	4.1\|811203\|33\|CP029154\|CRISPRCasFinder	811203-811235	33	NZ_MG205642	Paeniclostridium sordellii strain 7543-A plasmid pCS1-6, complete sequence	15023-15055	4	0.879
CP029154_6	6.1\|1579028\|25\|CP029154\|PILER-CR	1579028-1579052	25	MN856115	Bacteriophage sp. isolate 460, complete genome	4078-4102	4	0.84
CP029154_8	8.5\|1779969\|37\|CP029154\|CRISPRCasFinder	1779969-1780005	37	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	17905-17941	4	0.892
CP029154_6	6.1\|1579028\|25\|CP029154\|PILER-CR	1579028-1579052	25	NZ_CP051164	Geobacillus subterraneus strain CPW16 plasmid pBsrF30, complete sequence	10038-10062	5	0.8
CP029154_6	6.1\|1579028\|25\|CP029154\|PILER-CR	1579028-1579052	25	MN693026	Marine virus AFVG_117M72, complete genome	82935-82959	5	0.8
CP029154_12	12.4\|2814300\|42\|CP029154\|CRT	2814300-2814341	42	LN681539	Clostridium phage phiCD505, complete genome	18063-18104	5	0.881
CP029154_12	12.4\|2814300\|42\|CP029154\|CRT	2814300-2814341	42	JX145341	Clostridium phage phiMMP02, complete genome	17969-18010	5	0.881
CP029154_4	4.1\|811203\|33\|CP029154\|CRISPRCasFinder	811203-811235	33	NZ_MG205641	Paeniclostridium sordellii strain 7508-A plasmid pCS1-7, complete sequence	13139-13171	6	0.818
CP029154_4	4.1\|811203\|33\|CP029154\|CRISPRCasFinder	811203-811235	33	NZ_MG205642	Paeniclostridium sordellii strain 7543-A plasmid pCS1-6, complete sequence	13139-13171	6	0.818
CP029154_12	12.4\|2814300\|42\|CP029154\|CRT	2814300-2814341	42	KX228400	Clostridium phage CDKM15, complete genome	21206-21247	6	0.857
CP029154_19	19.2\|3760937\|30\|CP029154\|CRT	3760937-3760966	30	NC_007103	Bacillus cereus E33L plasmid pE33L466, complete sequence	140-169	6	0.8
CP029154_19	19.2\|3760937\|30\|CP029154\|CRT	3760937-3760966	30	NC_007103	Bacillus cereus E33L plasmid pE33L466, complete sequence	239-268	6	0.8
CP029154_19	19.2\|3760937\|30\|CP029154\|CRT	3760937-3760966	30	NZ_CP009967	Bacillus cereus E33L plasmid pBCO_1, complete sequence	321878-321907	6	0.8
CP029154_19	19.2\|3760937\|30\|CP029154\|CRT	3760937-3760966	30	MG209611	Aphanizomenon phage vB_AphaS-CL131, complete genome	32379-32408	6	0.8
CP029154_1	1.1\|32118\|31\|CP029154\|CRISPRCasFinder	32118-32148	31	MT533174	Escherichia phage CJ20, complete genome	109957-109987	7	0.774
CP029154_12	12.5\|2814169\|35\|CP029154\|PILER-CR	2814169-2814203	35	MN694223	Marine virus AFVG_250M234, complete genome	12543-12577	7	0.8
CP029154_19	19.2\|3760937\|30\|CP029154\|CRT	3760937-3760966	30	NC_007103	Bacillus cereus E33L plasmid pE33L466, complete sequence	410-439	7	0.767
CP029154_19	19.2\|3760937\|30\|CP029154\|CRT	3760937-3760966	30	NZ_CP009967	Bacillus cereus E33L plasmid pBCO_1, complete sequence	321734-321763	7	0.767
CP029154_19	19.2\|3760937\|30\|CP029154\|CRT	3760937-3760966	30	NZ_CP009336	Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence	72613-72642	7	0.767
CP029154_12	12.5\|2814169\|35\|CP029154\|PILER-CR	2814169-2814203	35	NZ_CP037437	Lactobacillus plantarum strain EM plasmid pEM8, complete sequence	21202-21236	8	0.771
CP029154_12	12.5\|2814169\|35\|CP029154\|PILER-CR	2814169-2814203	35	NZ_CP014325	Borrelia anserina Es isolate UTHSCSA plasmid lpA89, complete sequence	55631-55665	8	0.771
CP029154_12	12.7\|2814301\|34\|CP029154\|PILER-CR	2814301-2814334	34	NZ_CP015807	Borrelia mayonii strain MN14-1539 plasmid lp28-4	2137-2170	8	0.765
CP029154_12	12.7\|2814301\|34\|CP029154\|PILER-CR	2814301-2814334	34	NZ_CP015792	Borrelia mayonii strain MN14-1420 plasmid lp28-4, complete sequence	2137-2170	8	0.765
CP029154_19	19.2\|3760937\|30\|CP029154\|CRT	3760937-3760966	30	NZ_CP009336	Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence	73553-73582	8	0.733
CP029154_12	12.5\|2814169\|35\|CP029154\|PILER-CR	2814169-2814203	35	MN693362	Marine virus AFVG_25M506, complete genome	32054-32088	9	0.743
CP029154_17	17.1\|3262731\|31\|CP029154\|CRISPRCasFinder	3262731-3262761	31	LR606148	Rhizobium sp. Q54 genome assembly, plasmid: 5	444883-444913	9	0.71
CP029154_11	11.3\|2724359\|37\|CP029154\|PILER-CR	2724359-2724395	37	NC_025449	Escherichia phage ECML-134, complete genome	64499-64535	11	0.703
CP029154_11	11.3\|2724359\|37\|CP029154\|PILER-CR	2724359-2724395	37	KM607002	Enterobacteria phage RB55, complete genome	68097-68133	11	0.703
CP029154_11	11.3\|2724359\|37\|CP029154\|PILER-CR	2724359-2724395	37	KJ477684	Enterobacteria phage T4 strain wild, complete genome	68134-68170	11	0.703
CP029154_11	11.3\|2724359\|37\|CP029154\|PILER-CR	2724359-2724395	37	HM137666	Enterobacteria phage T4T, complete genome	68133-68169	11	0.703
CP029154_11	11.3\|2724359\|37\|CP029154\|PILER-CR	2724359-2724395	37	NC_000866	Enterobacteria phage T4, complete genome	68154-68190	11	0.703
CP029154_11	11.3\|2724359\|37\|CP029154\|PILER-CR	2724359-2724395	37	L13089	Bacteriophage T4 msp1-msp8 genes, complete cds's	2697-2733	11	0.703
CP029154_11	11.3\|2724359\|37\|CP029154\|PILER-CR	2724359-2724395	37	KJ477686	Enterobacteria phage T4 strain GT7, complete genome	68132-68168	11	0.703
CP029154_11	11.3\|2724359\|37\|CP029154\|PILER-CR	2724359-2724395	37	X57093	Bacteriophage T4 orfs between tRNA and e genes	238-274	11	0.703
CP029154_11	11.3\|2724359\|37\|CP029154\|PILER-CR	2724359-2724395	37	KJ477685	Enterobacteria phage T4 strain 147, complete genome	66027-66063	11	0.703
CP029154_11	11.3\|2724359\|37\|CP029154\|PILER-CR	2724359-2724395	37	KM607003	Enterobacteria phage RB59, complete genome	68110-68146	11	0.703
CP029154_19	19.3\|3760991\|48\|CP029154\|CRT	3760991-3761038	48	NZ_CP009336	Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence	90205-90252	15	0.688
CP029154_20	20.1\|4147981\|73\|CP029154\|CRISPRCasFinder	4147981-4148053	73	NZ_CP033215	Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence	3052-3124	23	0.685

1. spacer 6.1|1579028|25|CP029154|PILER-CR matches to NZ_MF547664 (Clostridioides difficile strain LIBA-6289 plasmid LIBA6289, complete sequence) position: , mismatch: 0, identity: 1.0

tattacatctaattctgtctcttca	CRISPR spacer
tattacatctaattctgtctcttca	Protospacer
*************************

2. spacer 6.3|1579017|36|CP029154|CRISPRCasFinder,CRT matches to NZ_MF547664 (Clostridioides difficile strain LIBA-6289 plasmid LIBA6289, complete sequence) position: , mismatch: 0, identity: 1.0

aagttaaatttattacatctaattctgtctcttcat	CRISPR spacer
aagttaaatttattacatctaattctgtctcttcat	Protospacer
************************************

3. spacer 7.4|1688635|36|CP029154|CRISPRCasFinder,CRT matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 0, identity: 1.0

ttggaaataagtataaagacagtgatatggaaatgg	CRISPR spacer
ttggaaataagtataaagacagtgatatggaaatgg	Protospacer
************************************

4. spacer 7.5|1688700|37|CP029154|CRISPRCasFinder,CRT matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 0, identity: 1.0

tatccatttcatatttagataaaatctctttaaatgc	CRISPR spacer
tatccatttcatatttagataaaatctctttaaatgc	Protospacer
*************************************

5. spacer 9.2|1782864|37|CP029154|CRT matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 0, identity: 1.0

actaaattagaggtcgagaaggctattgaatcaaaag	CRISPR spacer
actaaattagaggtcgagaaggctattgaatcaaaag	Protospacer
*************************************

6. spacer 9.3|1782930|36|CP029154|CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 0, identity: 1.0

tacacattttctcaaatttggacttcaattaaaaat	CRISPR spacer
tacacattttctcaaatttggacttcaattaaaaat	Protospacer
************************************

7. spacer 9.3|1782930|36|CP029154|CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 0, identity: 1.0

tacacattttctcaaatttggacttcaattaaaaat	CRISPR spacer
tacacattttctcaaatttggacttcaattaaaaat	Protospacer
************************************

8. spacer 9.3|1782930|36|CP029154|CRT matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 0, identity: 1.0

tacacattttctcaaatttggacttcaattaaaaat	CRISPR spacer
tacacattttctcaaatttggacttcaattaaaaat	Protospacer
************************************

9. spacer 10.2|1924261|36|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tctatatctgtttcaaaatctgttatgaaatactcc	CRISPR spacer
tctatatctgtttcaaaatctgttatgaaatactcc	Protospacer
************************************

10. spacer 10.2|1924261|36|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 0, identity: 1.0

tctatatctgtttcaaaatctgttatgaaatactcc	CRISPR spacer
tctatatctgtttcaaaatctgttatgaaatactcc	Protospacer
************************************

11. spacer 10.2|1924261|36|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 0, identity: 1.0

tctatatctgtttcaaaatctgttatgaaatactcc	CRISPR spacer
tctatatctgtttcaaaatctgttatgaaatactcc	Protospacer
************************************

12. spacer 12.7|2814301|34|CP029154|PILER-CR matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 0, identity: 1.0

acattatataagatagctaaaaatcttttaggca	CRISPR spacer
acattatataagatagctaaaaatcttttaggca	Protospacer
**********************************

13. spacer 1.1|32118|31|CP029154|CRISPRCasFinder matches to NZ_CP033215 (Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.968

agaataaactgaacgcatgtgaagtttgttt	CRISPR spacer
agaataaactgaacacatgtgaagtttgttt	Protospacer
**************.****************

14. spacer 7.2|1688502|37|CP029154|CRISPRCasFinder,CRT matches to HM568888 (Clostridium phage phiCD38-2, complete genome) position: , mismatch: 1, identity: 0.973

tacatcctcattaatttctttgctatcccaaacagca	CRISPR spacer
tacatcctcattagtttctttgctatcccaaacagca	Protospacer
*************.***********************

15. spacer 7.9|1688962|36|CP029154|CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 1, identity: 0.972

tatatattagatgtcaatgtcaaggatacaaaattt	CRISPR spacer
tatatattagatgtcaatatcaaggatacaaaattt	Protospacer
******************.*****************

16. spacer 7.9|1688962|36|CP029154|CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 1, identity: 0.972

tatatattagatgtcaatgtcaaggatacaaaattt	CRISPR spacer
tatatattagatgtcaatatcaaggatacaaaattt	Protospacer
******************.*****************

17. spacer 7.9|1688962|36|CP029154|CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 1, identity: 0.972

tatatattagatgtcaatgtcaaggatacaaaattt	CRISPR spacer
tatatattagatgtcaatatcaaggatacaaaattt	Protospacer
******************.*****************

18. spacer 7.9|1688962|36|CP029154|CRISPRCasFinder,CRT matches to NC_028838 (Clostridium phage phiCD506, complete genome) position: , mismatch: 1, identity: 0.972

tatatattagatgtcaatgtcaaggatacaaaattt	CRISPR spacer
tatatattagatgtcaatatcaaggatacaaaattt	Protospacer
******************.*****************

19. spacer 7.9|1688962|36|CP029154|CRISPRCasFinder,CRT matches to LN681538 (Clostridium phage phiCD481-1, complete genome) position: , mismatch: 1, identity: 0.972

tatatattagatgtcaatgtcaaggatacaaaattt	CRISPR spacer
tatatattagatgtcaatatcaaggatacaaaattt	Protospacer
******************.*****************

20. spacer 8.1|1779904|37|CP029154|PILER-CR,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 1, identity: 0.973

ttatctgcgtcttctgaaatagcatactcttcaagag	CRISPR spacer
ttatctgcatcttctgaaatagcatactcttcaagag	Protospacer
********.****************************

21. spacer 8.1|1779904|37|CP029154|PILER-CR,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 1, identity: 0.973

ttatctgcgtcttctgaaatagcatactcttcaagag	CRISPR spacer
ttatctgcatcttctgaaatagcatactcttcaagag	Protospacer
********.****************************

22. spacer 8.1|1779904|37|CP029154|PILER-CR,CRT matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 1, identity: 0.973

ttatctgcgtcttctgaaatagcatactcttcaagag	CRISPR spacer
ttatctgcatcttctgaaatagcatactcttcaagag	Protospacer
********.****************************

23. spacer 9.5|1782864|38|CP029154|CRISPRCasFinder matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 1, identity: 0.974

actaaattagaggtcgagaaggctattgaatcaaaagg	CRISPR spacer
actaaattagaggtcgagaaggctattgaatcaaaaga	Protospacer
*************************************.

24. spacer 9.6|1782930|37|CP029154|CRISPRCasFinder matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 1, identity: 0.973

tacacattttctcaaatttggacttcaattaaaaatg	CRISPR spacer
tacacattttctcaaatttggacttcaattaaaaata	Protospacer
************************************.

25. spacer 9.6|1782930|37|CP029154|CRISPRCasFinder matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 1, identity: 0.973

tacacattttctcaaatttggacttcaattaaaaatg	CRISPR spacer
tacacattttctcaaatttggacttcaattaaaaata	Protospacer
************************************.

26. spacer 9.6|1782930|37|CP029154|CRISPRCasFinder matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 1, identity: 0.973

tacacattttctcaaatttggacttcaattaaaaatg	CRISPR spacer
tacacattttctcaaatttggacttcaattaaaaata	Protospacer
************************************.

27. spacer 9.8|1782866|38|CP029154|PILER-CR matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 1, identity: 0.974

actaaattagaggtcgagaaggctattgaatcaaaagg	CRISPR spacer
actaaattagaggtcgagaaggctattgaatcaaaaga	Protospacer
*************************************.

28. spacer 10.3|1924326|35|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 1, identity: 0.971

aataacttatctatgaaattaaatactgtaacttg	CRISPR spacer
aatagcttatctatgaaattaaatactgtaacttg	Protospacer
****.******************************

29. spacer 10.5|1924455|36|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.972

tttcaacagtggtggtggtcgaggagtagaagttct	CRISPR spacer
tttcaacagtggtggtggtcgaggagtagaagtttt	Protospacer
**********************************.*

30. spacer 10.5|1924455|36|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.972

tttcaacagtggtggtggtcgaggagtagaagttct	CRISPR spacer
tttcaacagtggtggtggtcgaggagtagaagtttt	Protospacer
**********************************.*

31. spacer 10.5|1924455|36|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to MF547662 (Clostridioides phage LIBA6276, complete genome) position: , mismatch: 1, identity: 0.972

tttcaacagtggtggtggtcgaggagtagaagttct	CRISPR spacer
tttcaacagtggtggtggtcgaggagtagaagtttt	Protospacer
**********************************.*

32. spacer 10.5|1924455|36|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to MF547663 (Clostridioides phage LIBA2945, complete genome) position: , mismatch: 1, identity: 0.972

tttcaacagtggtggtggtcgaggagtagaagttct	CRISPR spacer
tttcaacagtggtggtggtcgaggagtagaagtttt	Protospacer
**********************************.*

33. spacer 10.5|1924455|36|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 1, identity: 0.972

tttcaacagtggtggtggtcgaggagtagaagttct	CRISPR spacer
tttcaacagtggtggtggtcgaggagtagaagtttt	Protospacer
**********************************.*

34. spacer 10.5|1924455|36|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 1, identity: 0.972

tttcaacagtggtggtggtcgaggagtagaagttct	CRISPR spacer
tttcaacagtggtggtggtcgaggagtagaagtttt	Protospacer
**********************************.*

35. spacer 12.7|2814301|34|CP029154|PILER-CR matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 1, identity: 0.971

acattatataagatagctaaaaatcttttaggca	CRISPR spacer
acattatataagatagctaaaaatcttttaggta	Protospacer
********************************.*

36. spacer 12.7|2814301|34|CP029154|PILER-CR matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 1, identity: 0.971

acattatataagatagctaaaaatcttttaggca	CRISPR spacer
acattatataagatagctaaaaatcttttaggta	Protospacer
********************************.*

37. spacer 19.7|3761261|21|CP029154|CRT matches to MN480762 (Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence) position: , mismatch: 1, identity: 0.952

taccaaaccatttgctcccgt	CRISPR spacer
taccaaaccagttgctcccgt	Protospacer
********** **********

38. spacer 19.8|3761306|21|CP029154|CRT matches to MN480762 (Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence) position: , mismatch: 1, identity: 0.952

taccaaaccatttgctcccgt	CRISPR spacer
taccaaaccagttgctcccgt	Protospacer
********** **********

39. spacer 7.2|1688502|37|CP029154|CRISPRCasFinder,CRT matches to KU057941 (Clostridium phage CDSH1, complete genome) position: , mismatch: 2, identity: 0.946

tacatcctcattaatttctttgctatcccaaacagca	CRISPR spacer
tacatcctcattagtttctttactatcccaaacagca	Protospacer
*************.*******.***************

40. spacer 7.2|1688502|37|CP029154|CRISPRCasFinder,CRT matches to NC_028905 (Clostridium phage phiCD111, complete genome) position: , mismatch: 2, identity: 0.946

tacatcctcattaatttctttgctatcccaaacagca	CRISPR spacer
tacatcctcattagtttctttactatcccaaacagca	Protospacer
*************.*******.***************

41. spacer 7.2|1688502|37|CP029154|CRISPRCasFinder,CRT matches to LN881738 (Escherichia phage slur17, complete genome) position: , mismatch: 2, identity: 0.946

tacatcctcattaatttctttgctatcccaaacagca	CRISPR spacer
tacatcctcattagtttctttactatcccaaacagca	Protospacer
*************.*******.***************

42. spacer 7.3|1688568|38|CP029154|CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 2, identity: 0.947

ctcttacgcttttcaatcactttttccttgctaaaatt	CRISPR spacer
cccttacgcttttcaatcattttttccttgctaaaatt	Protospacer
*.*****************.******************

43. spacer 7.3|1688568|38|CP029154|CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 2, identity: 0.947

ctcttacgcttttcaatcactttttccttgctaaaatt	CRISPR spacer
cccttacgcttttcaatcattttttccttgctaaaatt	Protospacer
*.*****************.******************

44. spacer 7.3|1688568|38|CP029154|CRISPRCasFinder,CRT matches to LN681538 (Clostridium phage phiCD481-1, complete genome) position: , mismatch: 2, identity: 0.947

ctcttacgcttttcaatcactttttccttgctaaaatt	CRISPR spacer
cccttacgcttttcaatcattttttccttgctaaaatt	Protospacer
*.*****************.******************

45. spacer 7.3|1688568|38|CP029154|CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 2, identity: 0.947

ctcttacgcttttcaatcactttttccttgctaaaatt	CRISPR spacer
cccttacgcttttcaatcattttttccttgctaaaatt	Protospacer
*.*****************.******************

46. spacer 7.6|1688766|37|CP029154|CRISPRCasFinder,CRT matches to GU949551 (Clostridium phage phiCD6356, complete genome) position: , mismatch: 2, identity: 0.946

atgttattacataaaaattcttcatctataactttaa	CRISPR spacer
atattattacataaaaattcttcgtctataactttaa	Protospacer
**.********************.*************

47. spacer 7.9|1688962|36|CP029154|CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 2, identity: 0.944

tatatattagatgtcaatgtcaaggatacaaaattt	CRISPR spacer
tatatattagatatcaatgtcaagaatacaaaattt	Protospacer
************.***********.***********

48. spacer 7.9|1688962|36|CP029154|CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 2, identity: 0.944

tatatattagatgtcaatgtcaaggatacaaaattt	CRISPR spacer
tatatattagatatcaatgtcaagaatacaaaattt	Protospacer
************.***********.***********

49. spacer 7.9|1688962|36|CP029154|CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 2, identity: 0.944

tatatattagatgtcaatgtcaaggatacaaaattt	CRISPR spacer
tatatattagatatcaatgtcaagaatacaaaattt	Protospacer
************.***********.***********

50. spacer 7.9|1688962|36|CP029154|CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 2, identity: 0.944

tatatattagatgtcaatgtcaaggatacaaaattt	CRISPR spacer
tatatattagatatcaatgtcaagaatacaaaattt	Protospacer
************.***********.***********

51. spacer 7.10|1689027|38|CP029154|CRISPRCasFinder,CRT matches to NZ_MG973074 (Clostridioides difficile strain HSJD-312 plasmid pHSJD-312, complete sequence) position: , mismatch: 2, identity: 0.947

ccatcttttgttgctttacataaatttatattacttac	CRISPR spacer
ccatcttttgttgctttgcatagatttatattacttac	Protospacer
*****************.****.***************

52. spacer 8.1|1779904|37|CP029154|PILER-CR,CRT matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 2, identity: 0.946

ttatctgcgtcttctgaaatagcatactcttcaagag	CRISPR spacer
ttttctgcatcttctgaaatagcatactcttcaagag	Protospacer
** *****.****************************

53. spacer 8.4|1779903|38|CP029154|CRISPRCasFinder matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 2, identity: 0.947

tttatctgcgtcttctgaaatagcatactcttcaagag	CRISPR spacer
attatctgcatcttctgaaatagcatactcttcaagag	Protospacer
 ********.****************************

54. spacer 8.4|1779903|38|CP029154|CRISPRCasFinder matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 2, identity: 0.947

tttatctgcgtcttctgaaatagcatactcttcaagag	CRISPR spacer
attatctgcatcttctgaaatagcatactcttcaagag	Protospacer
 ********.****************************

55. spacer 8.4|1779903|38|CP029154|CRISPRCasFinder matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 2, identity: 0.947

tttatctgcgtcttctgaaatagcatactcttcaagag	CRISPR spacer
attatctgcatcttctgaaatagcatactcttcaagag	Protospacer
 ********.****************************

56. spacer 10.1|1924196|36|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to MF547663 (Clostridioides phage LIBA2945, complete genome) position: , mismatch: 2, identity: 0.944

attgttttaccttctaaaaggtcacatatatttatt	CRISPR spacer
attatttcaccttctaaaaggtcacatatatttatt	Protospacer
***.***.****************************

57. spacer 10.1|1924196|36|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 2, identity: 0.944

attgttttaccttctaaaaggtcacatatatttatt	CRISPR spacer
attgtttcaccttctaaaatgtcacatatatttatt	Protospacer
*******.*********** ****************

58. spacer 10.1|1924196|36|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 2, identity: 0.944

attgttttaccttctaaaaggtcacatatatttatt	CRISPR spacer
attgtttcaccttctaaaatgtcacatatatttatt	Protospacer
*******.*********** ****************

59. spacer 10.1|1924196|36|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.944

attgttttaccttctaaaaggtcacatatatttatt	CRISPR spacer
attgtttcaccttctaaaatgtcacatatatttatt	Protospacer
*******.*********** ****************

60. spacer 10.6|1924520|38|CP029154|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MF547664 (Clostridioides difficile strain LIBA-6289 plasmid LIBA6289, complete sequence) position: , mismatch: 2, identity: 0.947

tttataacctttaattacacctcccatatcaccaccac	CRISPR spacer
cttgtaacctttaattacacctcccatatcaccaccac	Protospacer
.**.**********************************

61. spacer 12.7|2814301|34|CP029154|PILER-CR matches to KX228400 (Clostridium phage CDKM15, complete genome) position: , mismatch: 2, identity: 0.941

acattatataagatagctaaaaatcttttaggca	CRISPR spacer
acattatataagatagctaaaaatctcttaggta	Protospacer
**************************.*****.*

62. spacer 7.2|1688502|37|CP029154|CRISPRCasFinder,CRT matches to NC_028958 (Clostridium phage phiCD146, complete genome) position: , mismatch: 3, identity: 0.919

tacatcctcattaatttctttgctatcccaaacagca	CRISPR spacer
tatatcctcattagtttctttgctatcccaaacagcg	Protospacer
**.**********.**********************.

63. spacer 8.2|1779970|36|CP029154|PILER-CR,CRT matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.917

gttgtaagaagtatcattctattttttaatctttct	CRISPR spacer
attggaggaagtatcattctattttttaatctttct	Protospacer
.*** *.*****************************

64. spacer 8.4|1779903|38|CP029154|CRISPRCasFinder matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 3, identity: 0.921

tttatctgcgtcttctgaaatagcatactcttcaagag	CRISPR spacer
attttctgcatcttctgaaatagcatactcttcaagag	Protospacer
 ** *****.****************************

65. spacer 12.4|2814300|42|CP029154|CRT matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 3, identity: 0.929

tacattatataagatagctaaaaatcttttaggcaaatttac	CRISPR spacer
tacattatataagatagctaaaaatcttttaggcaaaggttc	Protospacer
*************************************  * *

66. spacer 4.1|811203|33|CP029154|CRISPRCasFinder matches to NZ_MG205641 (Paeniclostridium sordellii strain 7508-A plasmid pCS1-7, complete sequence) position: , mismatch: 4, identity: 0.879

aatgactcaaaagcagttactggatggcaaacc	CRISPR spacer
aataactcaaaagcagttacgggatggcaaatt	Protospacer
***.**************** **********..

67. spacer 4.1|811203|33|CP029154|CRISPRCasFinder matches to NZ_MG205642 (Paeniclostridium sordellii strain 7543-A plasmid pCS1-6, complete sequence) position: , mismatch: 4, identity: 0.879

aatgactcaaaagcagttactggatggcaaacc	CRISPR spacer
aataactcaaaagcagttacgggatggcaaatt	Protospacer
***.**************** **********..

68. spacer 6.1|1579028|25|CP029154|PILER-CR matches to MN856115 (Bacteriophage sp. isolate 460, complete genome) position: , mismatch: 4, identity: 0.84

tattacatctaattctgtctcttca	CRISPR spacer
cattacatctaattctttctcatct	Protospacer
.*************** **** **

69. spacer 8.5|1779969|37|CP029154|CRISPRCasFinder matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.892

tgttgtaagaagtatcattctattttttaatctttct	CRISPR spacer
aattggaggaagtatcattctattttttaatctttct	Protospacer
 .*** *.*****************************

70. spacer 6.1|1579028|25|CP029154|PILER-CR matches to NZ_CP051164 (Geobacillus subterraneus strain CPW16 plasmid pBsrF30, complete sequence) position: , mismatch: 5, identity: 0.8

tattacatctaattctgtctcttca	CRISPR spacer
aattgcatctaattctgtctctaat	Protospacer
 ***.*****************

71. spacer 6.1|1579028|25|CP029154|PILER-CR matches to MN693026 (Marine virus AFVG_117M72, complete genome) position: , mismatch: 5, identity: 0.8

tattacatctaattctgtctcttca	CRISPR spacer
cattacatctaattctttctctaat	Protospacer
.*************** *****

72. spacer 12.4|2814300|42|CP029154|CRT matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 5, identity: 0.881

tacattatataagatagctaaaaatcttttaggcaaatttac	CRISPR spacer
tacattatataagatagctaaaaatcttttaggtaagggttc	Protospacer
*********************************.**.  * *

73. spacer 12.4|2814300|42|CP029154|CRT matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 5, identity: 0.881

tacattatataagatagctaaaaatcttttaggcaaatttac	CRISPR spacer
tacattatataagatagctaaaaatcttttaggtaagggttc	Protospacer
*********************************.**.  * *

74. spacer 4.1|811203|33|CP029154|CRISPRCasFinder matches to NZ_MG205641 (Paeniclostridium sordellii strain 7508-A plasmid pCS1-7, complete sequence) position: , mismatch: 6, identity: 0.818

aatgactcaaaagcagttactggatggcaaacc	CRISPR spacer
tctagctcaaaagcagttacgggatggcaaact	Protospacer
  *..*************** ***********.

75. spacer 4.1|811203|33|CP029154|CRISPRCasFinder matches to NZ_MG205642 (Paeniclostridium sordellii strain 7543-A plasmid pCS1-6, complete sequence) position: , mismatch: 6, identity: 0.818

aatgactcaaaagcagttactggatggcaaacc	CRISPR spacer
tctagctcaaaagcagttacgggatggcaaact	Protospacer
  *..*************** ***********.

76. spacer 12.4|2814300|42|CP029154|CRT matches to KX228400 (Clostridium phage CDKM15, complete genome) position: , mismatch: 6, identity: 0.857

tacattatataagatagctaaaaatcttttaggcaaatttac	CRISPR spacer
tacattatataagatagctaaaaatctcttaggtaagggttc	Protospacer
***************************.*****.**.  * *

77. spacer 19.2|3760937|30|CP029154|CRT matches to NC_007103 (Bacillus cereus E33L plasmid pE33L466, complete sequence) position: , mismatch: 6, identity: 0.8

tgctactccatttgctcccgttgctcctac	CRISPR spacer
cgttactcctgttgctcccgttgctcctgt	Protospacer
.*.******  *****************..

78. spacer 19.2|3760937|30|CP029154|CRT matches to NC_007103 (Bacillus cereus E33L plasmid pE33L466, complete sequence) position: , mismatch: 6, identity: 0.8

tgctactccatttgctcccgttgctcctac	CRISPR spacer
cgttactcctgttgctcccgttgctcctgt	Protospacer
.*.******  *****************..

79. spacer 19.2|3760937|30|CP029154|CRT matches to NZ_CP009967 (Bacillus cereus E33L plasmid pBCO_1, complete sequence) position: , mismatch: 6, identity: 0.8

tgctactccatttgctcccgttgctcctac	CRISPR spacer
cgttactcctgttgctcccgttgctcctgt	Protospacer
.*.******  *****************..

80. spacer 19.2|3760937|30|CP029154|CRT matches to MG209611 (Aphanizomenon phage vB_AphaS-CL131, complete genome) position: , mismatch: 6, identity: 0.8

tgctactccatttgctcccgttgctcctac	CRISPR spacer
cgttgctcccgttgctcccgttgctcctat	Protospacer
.*.*.****  ******************.

81. spacer 1.1|32118|31|CP029154|CRISPRCasFinder matches to MT533174 (Escherichia phage CJ20, complete genome) position: , mismatch: 7, identity: 0.774

agaataaactgaacgcatgtgaagtttgttt	CRISPR spacer
caattaacccgaacgcatgtgaagtttatat	Protospacer
 .* *** *.*****************.* *

82. spacer 12.5|2814169|35|CP029154|PILER-CR matches to MN694223 (Marine virus AFVG_250M234, complete genome) position: , mismatch: 7, identity: 0.8

ttaaag---ctacataataaaaaattaagaaaaagaaa	CRISPR spacer
---aagttcctacaaaataaaaaattaaaaaaaatata	Protospacer
   ***   ***** *************.***** * *

83. spacer 19.2|3760937|30|CP029154|CRT matches to NC_007103 (Bacillus cereus E33L plasmid pE33L466, complete sequence) position: , mismatch: 7, identity: 0.767

tgctactccatttgctcccgttgctcctac	CRISPR spacer
cgtcactcctgttgctcccgttgctcctgt	Protospacer
.*..*****  *****************..

84. spacer 19.2|3760937|30|CP029154|CRT matches to NZ_CP009967 (Bacillus cereus E33L plasmid pBCO_1, complete sequence) position: , mismatch: 7, identity: 0.767

tgctactccatttgctcccgttgctcctac	CRISPR spacer
cgtcactcctgttgctcccgttgctcctgt	Protospacer
.*..*****  *****************..

85. spacer 19.2|3760937|30|CP029154|CRT matches to NZ_CP009336 (Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.767

tgctactccatttgctcccgttgctcctac	CRISPR spacer
aattgctccgattgctcccgttgctcctgc	Protospacer
 ..*.****. *****************.*

86. spacer 12.5|2814169|35|CP029154|PILER-CR matches to NZ_CP037437 (Lactobacillus plantarum strain EM plasmid pEM8, complete sequence) position: , mismatch: 8, identity: 0.771

----ttaaagctacataataaaaaattaagaaaaagaaa	CRISPR spacer
cttgttag----atataataaaaaatcaataaaaagaaa	Protospacer
    ***.    *.************.** *********

87. spacer 12.5|2814169|35|CP029154|PILER-CR matches to NZ_CP014325 (Borrelia anserina Es isolate UTHSCSA plasmid lpA89, complete sequence) position: , mismatch: 8, identity: 0.771

ttaaagctac---ataataaaaaattaagaaaaagaaa	CRISPR spacer
---aacttatgagataataaaaacttaacaaaaagaaa	Protospacer
   ** .**.   ********** **** *********

88. spacer 12.7|2814301|34|CP029154|PILER-CR matches to NZ_CP015807 (Borrelia mayonii strain MN14-1539 plasmid lp28-4) position: , mismatch: 8, identity: 0.765

acattatataagatagctaaaaatcttttaggca	CRISPR spacer
taaatatataaaatagctaaaaatcatttatcaa	Protospacer
  * *******.************* ****   *

89. spacer 12.7|2814301|34|CP029154|PILER-CR matches to NZ_CP015792 (Borrelia mayonii strain MN14-1420 plasmid lp28-4, complete sequence) position: , mismatch: 8, identity: 0.765

acattatataagatagctaaaaatcttttaggca	CRISPR spacer
taaatatataaaatagctaaaaatcatttatcaa	Protospacer
  * *******.************* ****   *

90. spacer 19.2|3760937|30|CP029154|CRT matches to NZ_CP009336 (Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.733

tgctactccatttgctcccgttgctcctac	CRISPR spacer
ggtcgctcccgttgctcccgttgctccttt	Protospacer
 *...****  ***************** .

91. spacer 12.5|2814169|35|CP029154|PILER-CR matches to MN693362 (Marine virus AFVG_25M506, complete genome) position: , mismatch: 9, identity: 0.743

ttaaagctacataataaaaaattaagaaaaagaaa	CRISPR spacer
tgtaataaacataatcaaaaattatgaaaaagatt	Protospacer
*  **   ******* ******** ********

92. spacer 17.1|3262731|31|CP029154|CRISPRCasFinder matches to LR606148 (Rhizobium sp. Q54 genome assembly, plasmid: 5) position: , mismatch: 9, identity: 0.71

cactatctctggtattggcggatttatcata	CRISPR spacer
cgagcaacttggtattggcggatttatgata	Protospacer
*.     ..****************** ***

93. spacer 11.3|2724359|37|CP029154|PILER-CR matches to NC_025449 (Escherichia phage ECML-134, complete genome) position: , mismatch: 11, identity: 0.703

ataataaaacttctattatatctactatatcaatatt	CRISPR spacer
cactccaaacttctattatatctactgtaccactgat	Protospacer
    . ********************.**.** *. *

94. spacer 11.3|2724359|37|CP029154|PILER-CR matches to KM607002 (Enterobacteria phage RB55, complete genome) position: , mismatch: 11, identity: 0.703

ataataaaacttctattatatctactatatcaatatt	CRISPR spacer
cgctccaaacttctattatatctactgtaccactgat	Protospacer
    . ********************.**.** *. *

95. spacer 11.3|2724359|37|CP029154|PILER-CR matches to KJ477684 (Enterobacteria phage T4 strain wild, complete genome) position: , mismatch: 11, identity: 0.703

ataataaaacttctattatatctactatatcaatatt	CRISPR spacer
cgctccaaacttctattatatctactgtaccactgat	Protospacer
    . ********************.**.** *. *

96. spacer 11.3|2724359|37|CP029154|PILER-CR matches to HM137666 (Enterobacteria phage T4T, complete genome) position: , mismatch: 11, identity: 0.703

ataataaaacttctattatatctactatatcaatatt	CRISPR spacer
cgctccaaacttctattatatctactgtaccactgat	Protospacer
    . ********************.**.** *. *

97. spacer 11.3|2724359|37|CP029154|PILER-CR matches to NC_000866 (Enterobacteria phage T4, complete genome) position: , mismatch: 11, identity: 0.703

ataataaaacttctattatatctactatatcaatatt	CRISPR spacer
cgctccaaacttctattatatctactgtaccactgat	Protospacer
    . ********************.**.** *. *

98. spacer 11.3|2724359|37|CP029154|PILER-CR matches to L13089 (Bacteriophage T4 msp1-msp8 genes, complete cds's) position: , mismatch: 11, identity: 0.703

ataataaaacttctattatatctactatatcaatatt	CRISPR spacer
cgctccaaacttctattatatctactgtaccactgat	Protospacer
    . ********************.**.** *. *

99. spacer 11.3|2724359|37|CP029154|PILER-CR matches to KJ477686 (Enterobacteria phage T4 strain GT7, complete genome) position: , mismatch: 11, identity: 0.703

ataataaaacttctattatatctactatatcaatatt	CRISPR spacer
cgctccaaacttctattatatctactgtaccactgat	Protospacer
    . ********************.**.** *. *

100. spacer 11.3|2724359|37|CP029154|PILER-CR matches to X57093 (Bacteriophage T4 orfs between tRNA and e genes) position: , mismatch: 11, identity: 0.703

ataataaaacttctattatatctactatatcaatatt	CRISPR spacer
cgctccaaacttctattatatctactgtaccactgat	Protospacer
    . ********************.**.** *. *

101. spacer 11.3|2724359|37|CP029154|PILER-CR matches to KJ477685 (Enterobacteria phage T4 strain 147, complete genome) position: , mismatch: 11, identity: 0.703

ataataaaacttctattatatctactatatcaatatt	CRISPR spacer
cgctccaaacttctattatatctactgtaccactgat	Protospacer
    . ********************.**.** *. *

102. spacer 11.3|2724359|37|CP029154|PILER-CR matches to KM607003 (Enterobacteria phage RB59, complete genome) position: , mismatch: 11, identity: 0.703

ataataaaacttctattatatctactatatcaatatt	CRISPR spacer
cgctccaaacttctattatatctactgtaccactgat	Protospacer
    . ********************.**.** *. *

103. spacer 19.3|3760991|48|CP029154|CRT matches to NZ_CP009336 (Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence) position: , mismatch: 15, identity: 0.688

atttgcccctgttgctcctgttgctcctgtagctcctgctactccatt---------	CRISPR spacer
---------tgttgctcctgttgctcctgttgctcctgttgctcctccagcaggtcc	Protospacer
         ********************* *******.*.**** ..

104. spacer 20.1|4147981|73|CP029154|CRISPRCasFinder matches to NZ_CP033215 (Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence) position: , mismatch: 23, identity: 0.685

-ggataaatcccgttgcttaaagtgctaacgcacagcgccaacaaacaaacttcacatgc	CRISPR spacer
tatatatatgcagtt-ttcaaagtgctaacgcacagcgccaacaaacaaacttcacatgt	Protospacer
 . *** ** * *** .*.****************************************.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

273724 : 285520

Synechococcus_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWH79755.1\|273724_274237_-	nitroreductase family protein	A0A1V0E011	Clostridioides_phage	7.8e-84	87.6
AWH79756.1\|274686_275163_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.9e-26	45.8
AWH79757.1\|275168_275867_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	1.5e-45	43.9
AWH79758.1\|275878_277246_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.6e-49	31.0
AWH79759.1\|277239_278316_+	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	1.7e-64	42.2
AWH79760.1\|278309_278903_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.6e-25	40.4
AWH79761.1\|278895_280428_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH	E3SNU8	Prochlorococcus_phage	2.3e-38	49.7
AWH79762.1\|280438_281689_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
AWH79763.1\|281713_285520_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.0e-31	24.4

DBSCAN-SWA_2

397193 : 415671

Streptococcus_phage(100.0%)

integrase

attL 393695:393712|attR 415683:415700

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
393695:393712	attL	NA	NA	NA	NA
AWH79869.1\|397193_397520_+	DUF961 domain-containing protein	A0A1S5SF38	Streptococcus_phage	1.1e-25	53.4
AWH79870.1\|397535_397919_+	DUF961 domain-containing protein	A0A1S5SF96	Streptococcus_phage	8.9e-32	55.9
AWH79871.1\|398020_398785_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
AWH79872.1\|398883_400278_+	ATP-binding protein	A0A1S5SFB5	Streptococcus_phage	4.8e-176	65.7
AWH79873.1\|400455_401661_+	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
AWH79874.1\|401703_401925_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
AWH79875.1\|402041_402539_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
AWH79876.1\|402513_403020_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
AWH79877.1\|403003_405451_+	ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
AWH79878.1\|405453_407631_+	hypothetical protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
AWH79879.1\|407627_408629_+	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
AWH79880.1\|408625_409561_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	7.7e-170	99.0
AWH79881.1\|409833_409920_+	tetracycline resistance protein	NA	NA	NA	NA
AWH79882.1\|409935_411855_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	99.5
AWH79883.1\|411955_412141_+	conjugal transfer protein	D0R0F6	Streptococcus_phage	3.9e-17	67.9
AWH79884.1\|412200_412554_-	XRE family transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
AWH83257.1\|412758_412830_+	hypothetical protein	NA	NA	NA	NA
AWH79885.1\|413058_413481_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
AWH79886.1\|413477_413708_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
AWH79887.1\|413933_414185_-	hypothetical protein	NA	NA	NA	NA
AWH79888.1\|414168_414372_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
AWH79889.1\|414453_415671_+\|integrase	site-specific integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
415683:415700	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1465061 : 1527927

Clostridium_phage(46.15%)

portal,plate,tRNA,tail,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWH80761.1\|1465061_1465796_+\|protease	Clp protease	NA	NA	NA	NA
AWH80762.1\|1465918_1468333_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	3.3e-92	50.4
AWH80763.1\|1468335_1469394_+\|tRNA	tRNA 2-selenouridine(34) synthase MnmH	NA	NA	NA	NA
AWH80764.1\|1469387_1470722_+	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
AWH80765.1\|1470708_1471251_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
AWH80766.1\|1471538_1472585_+	DNA recombination/repair protein RecA	A0A0S2MVG1	Bacillus_phage	2.7e-123	63.5
AWH83291.1\|1472760_1474302_+	ribonuclease Y	NA	NA	NA	NA
AWH80767.1\|1474936_1476718_+	DNA helicase	NA	NA	NA	NA
AWH80768.1\|1476799_1477330_-	signal peptidase I	NA	NA	NA	NA
AWH80769.1\|1477369_1478194_-	undecaprenyl-diphosphatase	NA	NA	NA	NA
AWH80770.1\|1478450_1479359_+	recombinase	NA	NA	NA	NA
AWH80771.1\|1479502_1480948_+	adenylosuccinate lyase	NA	NA	NA	NA
AWH80772.1\|1481258_1481711_+	MarR family transcriptional regulator	NA	NA	NA	NA
AWH80773.1\|1482114_1483692_+	PTS maltose transporter subunit IICB	NA	NA	NA	NA
AWH80774.1\|1483839_1484592_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
AWH80775.1\|1484730_1486092_+	6-phospho-alpha-glucosidase	NA	NA	NA	NA
AWH80776.1\|1486182_1487379_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
AWH80777.1\|1487763_1488714_+	galactose-1-phosphate uridylyltransferase	NA	NA	NA	NA
AWH80778.1\|1488866_1489619_+	exodeoxyribonuclease III	E3T4M6	Cafeteria_roenbergensis_virus	3.2e-57	44.8
AWH80779.1\|1489710_1490487_-	exonuclease	NA	NA	NA	NA
AWH80780.1\|1490801_1492700_+	glutamine synthetase	NA	NA	NA	NA
AWH83292.1\|1492827_1493949_-	galactosyldiacylglycerol synthase	NA	NA	NA	NA
AWH80781.1\|1494147_1494480_+	PadR family transcriptional regulator	NA	NA	NA	NA
AWH80782.1\|1494466_1495525_+	DUF1700 domain-containing protein	NA	NA	NA	NA
AWH80783.1\|1495517_1496588_+	hypothetical protein	NA	NA	NA	NA
AWH80784.1\|1496689_1497226_+	lipoprotein	NA	NA	NA	NA
AWH80785.1\|1497341_1498049_+	lantibiotic ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	9.6e-56	48.5
AWH80786.1\|1498050_1498767_+	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	NA	NA	NA	NA
AWH80787.1\|1498768_1499527_+	lantibiotic immunity ABC transporter MutG family permease subunit	NA	NA	NA	NA
AWH80788.1\|1499661_1501050_+	sensor histidine kinase	NA	NA	NA	NA
AWH80789.1\|1501125_1501947_-	pyridoxamine kinase	NA	NA	NA	NA
AWH80790.1\|1502197_1503352_+	amidase domain-containing protein	NA	NA	NA	NA
AWH80791.1\|1503534_1503735_+	cold-shock protein	A0A1W6JNX5	Morganella_phage	2.7e-16	66.2
AWH80792.1\|1504155_1504584_+	CBS domain-containing protein	NA	NA	NA	NA
AWH80793.1\|1504726_1505482_-	peptidylprolyl isomerase	NA	NA	NA	NA
AWH80794.1\|1505602_1506019_-	hypothetical protein	NA	NA	NA	NA
AWH80795.1\|1506182_1506689_-	hypothetical protein	A0A0A8WEK1	Clostridium_phage	4.0e-56	67.1
AWH80796.1\|1506770_1507091_-	XRE family transcriptional regulator	A0A0A8WE28	Clostridium_phage	3.7e-23	54.5
AWH80797.1\|1507259_1507457_+	XRE family transcriptional regulator	NA	NA	NA	NA
AWH80798.1\|1507561_1508002_+	hypothetical protein	A0A090EUN5	Clostridium_phage	6.0e-32	51.4
AWH80799.1\|1508250_1508694_+	hypothetical protein	A0A1V0DZX9	Clostridioides_phage	2.0e-19	36.7
AWH80800.1\|1508698_1509763_+\|tail	phage tail sheath protein	A0A1V0DZX4	Clostridioides_phage	1.2e-97	53.1
AWH80801.1\|1509776_1510205_+\|portal	phage portal protein	A0A1V0DZX1	Clostridioides_phage	2.8e-34	51.8
AWH80802.1\|1510318_1510765_+\|portal	phage portal protein	A0A0A7RTP2	Clostridium_phage	1.8e-12	36.4
AWH80803.1\|1510791_1510959_+	hypothetical protein	NA	NA	NA	NA
AWH80804.1\|1510958_1513358_+	hypothetical protein	A0A1V0DZX3	Clostridioides_phage	6.4e-19	45.6
AWH80805.1\|1513357_1513780_+	hypothetical protein	A0A090DBR9	Clostridium_phage	1.7e-52	71.1
AWH80806.1\|1514061_1515594_+	cell wall hydrolase	A0A1V0DZX6	Clostridioides_phage	1.8e-237	79.7
AWH80807.1\|1515609_1515936_+	DUF2577 domain-containing protein	J9QE86	Clostridium_phage	2.3e-52	94.4
AWH80808.1\|1515935_1516364_+	DUF2634 domain-containing protein	A0A0A8WJ32	Clostridium_phage	5.8e-64	82.4
AWH80809.1\|1516356_1517409_+\|plate	baseplate protein J	A0A0A8WFP3	Clostridium_phage	5.7e-137	69.8
AWH80810.1\|1517405_1518104_+	DUF2313 domain-containing protein	A0A090D815	Clostridium_phage	5.5e-48	56.9
AWH80811.1\|1518104_1519091_+\|tail	phage tail protein	A0A2H4J039	uncultured_Caudovirales_phage	7.6e-59	46.8
AWH80812.1\|1519112_1524344_+	chromosome condensation regulator	A0A0A8WEY5	Clostridium_phage	3.4e-81	31.3
AWH80813.1\|1524360_1524714_+	hypothetical protein	A0A0A8WJF2	Clostridium_phage	5.5e-12	42.1
AWH80814.1\|1524976_1525237_+	hypothetical protein	E2ELK7	Clostridium_phage	9.9e-35	90.6
AWH80815.1\|1525460_1525916_-	hypothetical protein	NA	NA	NA	NA
AWH80816.1\|1526143_1526563_-	transcriptional regulator	S5MUV6	Brevibacillus_phage	5.4e-06	37.2
AWH80817.1\|1526861_1527071_+	XRE family transcriptional regulator	Q5YAA3	Bacillus_phage	5.9e-06	47.2
AWH80818.1\|1527090_1527312_+	hypothetical protein	NA	NA	NA	NA
AWH80819.1\|1527528_1527927_-	transcriptional regulator	A0A1L2JY18	Aeribacillus_phage	2.7e-07	29.7

DBSCAN-SWA_4

1609338 : 1619067

Pandoravirus(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWH80887.1\|1609338_1609923_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.7e-58	53.7
AWH80888.1\|1609915_1611274_+	aminodeoxychorismate synthase component I	S4VNU7	Pandoravirus	3.0e-37	41.2
AWH80889.1\|1611263_1612007_+	aminodeoxychorismate lyase	NA	NA	NA	NA
AWH80890.1\|1612040_1612742_+	hypothetical protein	NA	NA	NA	NA
AWH80891.1\|1612767_1613340_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	3.0e-44	51.6
AWH80892.1\|1613393_1614197_+	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	1.3e-24	30.0
AWH83296.1\|1614207_1614573_+	dihydroneopterin aldolase	NA	NA	NA	NA
AWH80893.1\|1614565_1615072_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	S4VNV0	Pandoravirus	2.5e-13	36.6
AWH80894.1\|1615052_1615838_+	3-deoxy-7-phosphoheptulonate synthase	E3T537	Cafeteria_roenbergensis_virus	1.0e-13	28.3
AWH80895.1\|1616092_1617883_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.2e-51	32.6
AWH80896.1\|1617894_1619067_+	RNA polymerase sigma factor RpoD	M4SMP8	Cyanophage	9.7e-37	36.8

DBSCAN-SWA_5

1744707 : 1800305

Clostridium_phage(83.02%)

capsid,holin,integrase,head,terminase,portal,tail

attL 1746548:1746575|attR 1801654:1801681

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWH81004.1\|1744707_1746402_+	biosynthetic-type acetolactate synthase large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	6.5e-50	29.2
1746548:1746575	attL	NA	NA	NA	NA
AWH81005.1\|1746759_1747890_-\|integrase	site-specific integrase	A0A0A8WIE1	Clostridium_phage	5.0e-216	99.5
AWH81006.1\|1748129_1748636_-	ImmA/IrrE family metallo-endopeptidase	A0A0A8WEK1	Clostridium_phage	1.5e-87	100.0
AWH81007.1\|1748898_1750488_-	hypothetical protein	A0A1S5SA14	Streptococcus_phage	4.0e-33	27.9
AWH81008.1\|1750511_1751057_-	XRE family transcriptional regulator	A0A0A8WJ60	Clostridium_phage	2.6e-45	53.3
AWH81009.1\|1751237_1751453_+	XRE family transcriptional regulator	A0A0A8WIG0	Clostridium_phage	3.8e-24	77.5
AWH81010.1\|1751483_1752257_+	Rha family transcriptional regulator	A0A0A8WIJ5	Clostridium_phage	4.6e-35	39.6
AWH81011.1\|1752376_1753207_+	phage antirepressor protein	A0A0A8WIE3	Clostridium_phage	4.4e-84	62.8
AWH81012.1\|1753253_1753463_+	hypothetical protein	NA	NA	NA	NA
AWH81013.1\|1753472_1753847_-	hypothetical protein	A0A1L5C299	Pseudoalteromonas_phage	2.2e-11	37.1
AWH81014.1\|1753922_1754120_+	XRE family transcriptional regulator	A0A0A8WE47	Clostridium_phage	4.9e-26	92.3
AWH81015.1\|1754150_1754543_+	DNA-binding protein	A0A0A8WHS2	Clostridium_phage	6.7e-59	94.6
AWH81016.1\|1754743_1755181_+	hypothetical protein	NA	NA	NA	NA
AWH81017.1\|1755192_1756359_+	DUF2800 domain-containing protein	S5MUB5	Brevibacillus_phage	1.1e-117	55.9
AWH81018.1\|1756373_1756709_+	hypothetical protein	NA	NA	NA	NA
AWH81019.1\|1756761_1757334_+	RNA polymerase subunit sigma-70	NA	NA	NA	NA
AWH81020.1\|1757356_1757929_+	DUF2815 domain-containing protein	S5MC21	Brevibacillus_phage	8.5e-63	66.7
AWH81021.1\|1757928_1759887_+	DNA polymerase I	A0A0A7RTL3	Clostridium_phage	5.4e-266	69.4
AWH81022.1\|1759898_1762316_+	hypothetical protein	A0A0A7RTG3	Clostridium_phage	0.0e+00	67.7
AWH81023.1\|1762597_1762924_+	VRR-NUC domain-containing protein	A0A2K5B272	Erysipelothrix_phage	8.7e-20	55.4
AWH81024.1\|1762872_1764243_+	ATP-dependent helicase	A0A1S7FYY5	Listeria_phage	8.4e-157	60.3
AWH81025.1\|1764396_1764876_+	hypothetical protein	I2E8Y5	Clostridium_phage	3.3e-36	51.6
AWH81026.1\|1765360_1765597_+	hypothetical protein	A0A0A8WJQ8	Clostridium_phage	3.3e-37	96.2
AWH81027.1\|1765899_1766874_+	hypothetical protein	NA	NA	NA	NA
AWH81028.1\|1766929_1767130_-	hypothetical protein	NA	NA	NA	NA
AWH81029.1\|1767110_1767404_+	hypothetical protein	NA	NA	NA	NA
AWH81030.1\|1767474_1768167_+	hypothetical protein	A0A0A8WFS6	Clostridium_phage	1.7e-121	98.3
AWH83301.1\|1768156_1769398_+\|terminase	PBSX family phage terminase large subunit	X5JAB3	Clostridium_phage	2.1e-244	99.0
AWH81031.1\|1769403_1770843_+\|portal	phage portal protein	A0A0A8WFC0	Clostridium_phage	5.3e-279	99.8
AWH81032.1\|1770832_1772326_+\|head	phage head morphogenesis protein	X5JAI9	Clostridium_phage	1.1e-284	96.8
AWH83302.1\|1772303_1772534_+	hypothetical protein	X5JAV8	Clostridium_phage	1.8e-35	100.0
AWH81033.1\|1772843_1773407_+	scaffolding protein	X5JAB4	Clostridium_phage	3.0e-84	89.3
AWH81034.1\|1773418_1774318_+\|capsid	capsid protein	A0A0A8WFI8	Clostridium_phage	2.8e-169	100.0
AWH81035.1\|1774317_1774551_+	hypothetical protein	A0A0A8WFD0	Clostridium_phage	3.2e-32	96.1
AWH81036.1\|1774560_1774962_+	hypothetical protein	X5JAJ0	Clostridium_phage	8.1e-68	97.0
AWH81037.1\|1774955_1775303_+	hypothetical protein	X5JAV9	Clostridium_phage	1.1e-57	99.1
AWH81038.1\|1775302_1775728_+	HK97 gp10 family phage protein	A0A0A8WFV8	Clostridium_phage	3.2e-75	97.9
AWH81039.1\|1775720_1776158_+	hypothetical protein	X5JAB5	Clostridium_phage	2.8e-74	92.4
AWH81040.1\|1776150_1776327_+	hypothetical protein	X5J9Z6	Clostridium_phage	5.5e-21	91.4
AWH81041.1\|1776327_1777638_+\|tail	phage tail protein	X5JAJ1	Clostridium_phage	7.3e-235	94.0
AWH81042.1\|1777654_1778125_+	hypothetical protein	A0A0A8WJ62	Clostridium_phage	7.0e-71	82.1
AWH81043.1\|1778196_1778637_+\|portal	phage portal protein	X5JAB6	Clostridium_phage	8.6e-47	63.7
AWH81044.1\|1778636_1778831_+	hypothetical protein	NA	NA	NA	NA
AWH81045.1\|1778977_1779139_+	hypothetical protein	A0A0A8WE04	Clostridium_phage	1.2e-14	84.3
AWH81046.1\|1780286_1781039_+	SHOCT domain-containing protein	A0A090DCP8	Clostridium_phage	6.2e-61	51.6
AWH81047.1\|1781342_1781516_+	CopG family transcriptional regulator	NA	NA	NA	NA
AWH83303.1\|1782071_1782467_+	hypothetical protein	X5JAW1	Clostridium_phage	9.4e-61	88.4
AWH81048.1\|1783104_1783683_+	zinc ribbon domain-containing protein	A0A0A8WFW4	Clostridium_phage	3.8e-87	90.3
AWH81049.1\|1783758_1786125_+	hypothetical protein	A0A0A8WJT6	Clostridium_phage	1.3e-282	71.3
AWH81050.1\|1786140_1786842_+	LysM peptidoglycan-binding domain-containing protein	A0A0A8WFE5	Clostridium_phage	8.4e-121	93.5
AWH81051.1\|1786834_1788799_+	cell wall hydrolase	A0A0A8WIF2	Clostridium_phage	6.1e-310	86.1
AWH81052.1\|1788812_1789073_+	DUF2577 domain-containing protein	A0A0A8WJ65	Clostridium_phage	2.5e-38	96.5
AWH81053.1\|1789077_1789497_+	DUF2634 domain-containing protein	A0A0A8WJV8	Clostridium_phage	3.9e-73	98.6
AWH81054.1\|1789497_1790544_+\|tail	phage tail protein	X5JAB8	Clostridium_phage	2.6e-182	94.2
AWH81055.1\|1790536_1791154_+	DUF2313 domain-containing protein	A0A0A8WII4	Clostridium_phage	8.8e-114	98.0
AWH81056.1\|1791165_1792158_+\|tail	phage tail protein	A3QSB7	Clostridium_virus	1.5e-160	94.1
AWH81057.1\|1793907_1794255_+	hypothetical protein	A3QSB8	Clostridium_virus	5.5e-57	100.0
AWH81058.1\|1794467_1795034_+	hypothetical protein	A0A0A8WFF2	Clostridium_phage	1.2e-37	78.7
AWH81059.1\|1795064_1795355_+	hypothetical protein	A0A0A8WIF5	Clostridium_phage	6.3e-46	100.0
AWH81060.1\|1795358_1795616_+\|holin	holin	A0A0A8WF70	Clostridium_phage	6.6e-39	95.3
AWH81061.1\|1796817_1797630_+	N-acetylmuramoyl-L-alanine amidase	A0A0K2SUC5	Clostridium_phage	1.3e-149	94.4
AWH81062.1\|1797786_1800078_+	cell wall-binding repeat-containing protein	NA	NA	NA	NA
AWH81063.1\|1800119_1800305_-	PemI	A0A0A8WHQ4	Clostridium_phage	7.6e-13	62.1
1801654:1801681	attR	NA	NA	NA	NA

DBSCAN-SWA_6

2556288 : 2570429

Clostridium_phage(71.43%)

holin,integrase

attL 2562606:2562622|attR 2577323:2577339

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWH81729.1\|2556288_2557035_-	N-acetylmuramoyl-L-alanine amidase	A0A0A8WHU0	Clostridium_phage	3.9e-84	67.5
AWH81730.1\|2557034_2557292_-\|holin	holin	A0A0A8WF70	Clostridium_phage	7.5e-35	83.5
AWH81731.1\|2557311_2557542_-	hypothetical protein	A0A0A8WEZ7	Clostridium_phage	4.8e-33	97.4
AWH81732.1\|2557599_2559147_-	hypothetical protein	B6SBV0	Clostridium_virus	7.2e-181	75.7
AWH81733.1\|2559281_2559464_-	hypothetical protein	J9QDY8	Clostridium_phage	1.2e-23	90.0
AWH81734.1\|2559769_2561263_-	hypothetical protein	J9QE87	Clostridium_phage	6.0e-108	55.2
AWH81735.1\|2561278_2561626_-	hypothetical protein	J9QED3	Clostridium_phage	1.9e-20	68.5
AWH83320.1\|2561613_2562897_-	DUF2313 domain-containing protein	A0A0A8WFK0	Clostridium_phage	5.7e-131	81.3
2562606:2562622	attL	NA	NA	NA	NA
AWH81736.1\|2563272_2563707_+	hypothetical protein	NA	NA	NA	NA
AWH81737.1\|2563794_2565354_-	cell wall-binding repeat-containing protein	A0A2R2ZGK6	Clostridioides_phage	1.9e-72	52.0
AWH81738.1\|2565558_2565999_+	hypothetical protein	A0A0A8WIE1	Clostridium_phage	1.9e-54	69.8
AWH81739.1\|2566040_2566700_+\|integrase	site-specific integrase	A0A0A8WIE1	Clostridium_phage	3.7e-62	55.0
AWH81740.1\|2567667_2568045_-	BlaI/MecI/CopY family transcriptional regulator	A0A0A8WJU1	Clostridium_phage	3.6e-54	91.2
AWH81741.1\|2568604_2568793_-	hypothetical protein	NA	NA	NA	NA
AWH81742.1\|2568953_2569304_+	DUF3796 domain-containing protein	NA	NA	NA	NA
AWH81743.1\|2569305_2569506_+	transcriptional regulator	A0A1V0E021	Clostridioides_phage	3.7e-05	45.8
AWH81744.1\|2569828_2570005_+	hypothetical protein	NA	NA	NA	NA
AWH81745.1\|2570228_2570429_+	cold-shock protein	A0A1X9IGI9	Lactococcus_phage	2.0e-19	71.4
2577323:2577339	attR	NA	NA	NA	NA

DBSCAN-SWA_7

2808767 : 2817357

Clostridium_phage(66.67%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWH81952.1\|2808767_2809151_-	transcriptional regulator	A0A090DCS9	Clostridium_phage	4.1e-61	89.8
AWH81953.1\|2809530_2809707_+	hypothetical protein	NA	NA	NA	NA
AWH81954.1\|2809932_2810133_+	cold-shock protein	A0A1X9IGI9	Lactococcus_phage	5.0e-18	68.3
AWH81955.1\|2810563_2811901_+	ATP-binding protein	X5JAC0	Clostridium_phage	1.3e-138	59.9
AWH81956.1\|2811943_2812525_+	accessory regulator	X5JB40	Clostridium_phage	1.0e-42	49.2
AWH81957.1\|2812542_2812704_+	cyclic lactone autoinducer peptide	NA	NA	NA	NA
AWH81958.1\|2812725_2813523_-	N-acetylmuramoyl-L-alanine amidase	A0A0A8WE15	Clostridium_phage	1.1e-140	90.7
AWH81959.1\|2813519_2813780_-\|holin	holin	A3QSC5	Clostridium_virus	7.9e-32	77.6
AWH81960.1\|2814649_2814808_-	hypothetical protein	J9QED5	Clostridium_phage	1.6e-08	63.5
AWH81961.1\|2815165_2816536_-	cell wall-binding protein Cwp29	A0A2R2ZGK6	Clostridioides_phage	1.6e-70	43.9
AWH81962.1\|2816934_2817357_+	hypothetical protein	X5JB41	Clostridium_phage	4.4e-48	69.8

DBSCAN-SWA_8

3017468 : 3077283

Clostridium_phage(96.59%)

transposase,holin,integrase,head,portal,plate,tail

attL 3015757:3015774|attR 3083374:3083391

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3015757:3015774	attL	NA	NA	NA	NA
AWH82132.1\|3017468_3017996_-	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	4.2e-08	28.0
AWH82133.1\|3018224_3019301_+	aminotransferase	NA	NA	NA	NA
AWH82134.1\|3019387_3020596_-	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
AWH82135.1\|3020946_3021330_-	transcriptional regulator	A0A090DCS9	Clostridium_phage	3.5e-68	100.0
AWH82136.1\|3021856_3022000_-	hypothetical protein	A0A0A8WJ06	Clostridium_phage	3.9e-17	100.0
AWH82137.1\|3022261_3022450_+	hypothetical protein	X5JA01	Clostridium_phage	1.8e-30	100.0
AWH82138.1\|3022698_3023403_-	hypothetical protein	Q24LF8	Clostridium_phage	9.8e-69	97.0
AWH82139.1\|3023404_3023836_-	hypothetical protein	Q24LG0	Clostridium_phage	1.9e-75	100.0
AWH82140.1\|3023853_3024450_-	hypothetical protein	Q24LG1	Clostridium_phage	1.8e-95	99.5
AWH82141.1\|3024962_3025259_-	hypothetical protein	Q24LG2	Clostridium_phage	1.8e-48	98.0
AWH82142.1\|3025275_3026091_-	N-acetylmuramoyl-L-alanine amidase	Q24LG3	Clostridium_phage	2.3e-154	99.6
AWH82143.1\|3026090_3026348_-\|holin	holin	Q24LG4	Clostridium_phage	1.1e-41	100.0
AWH82144.1\|3026367_3026598_-	hypothetical protein	Q24LG5	Clostridium_phage	9.7e-34	100.0
AWH82145.1\|3026633_3026816_-	hypothetical protein	Q24LG6	Clostridium_phage	7.7e-26	100.0
AWH82146.1\|3026815_3028087_-	hypothetical protein	A0A0K2SU84	Clostridium_phage	5.6e-131	61.6
AWH82147.1\|3028104_3028884_-\|tail	phage tail protein	A0A0A8WES5	Clostridium_phage	1.2e-123	98.8
AWH82148.1\|3028900_3029509_-	DUF2313 domain-containing protein	A0A090D815	Clostridium_phage	4.0e-111	100.0
AWH82149.1\|3029508_3030561_-\|plate	baseplate protein J	A0A0A8WFP3	Clostridium_phage	2.3e-194	100.0
AWH82150.1\|3030553_3030982_-	DUF2634 domain-containing protein	A0A0A8WJ32	Clostridium_phage	1.0e-76	100.0
AWH82151.1\|3030981_3031308_-	DUF2577 domain-containing protein	A0A0A8WIB5	Clostridium_phage	8.3e-55	100.0
AWH82152.1\|3031323_3032844_-	cell wall hydrolase	A0A090DCQ7	Clostridium_phage	1.4e-293	100.0
AWH82153.1\|3033102_3033345_-	hypothetical protein	A0A090D811	Clostridium_phage	7.0e-43	100.0
AWH83333.1\|3033365_3033563_-	hypothetical protein	A0A090D836	Clostridium_phage	9.8e-35	100.0
AWH82154.1\|3033652_3034288_-	LysM peptidoglycan-binding domain-containing protein	A0A090DBR9	Clostridium_phage	2.9e-120	99.5
AWH82155.1\|3034305_3034497_-	hypothetical protein	A0A090EUD7	Clostridium_phage	2.5e-27	100.0
AWH82156.1\|3034630_3034780_-	hypothetical protein	J9QED5	Clostridium_phage	2.2e-07	62.5
AWH83334.1\|3035241_3035808_-	SHOCT domain-containing protein	A0A090DCP8	Clostridium_phage	7.9e-77	100.0
AWH82157.1\|3036064_3038899_-\|tail	phage tail tape measure protein	A0A090D808	Clostridium_phage	2.4e-238	95.4
AWH82158.1\|3039075_3039546_-	hypothetical protein	A0A090EUD0	Clostridium_phage	9.7e-81	100.0
AWH82159.1\|3039577_3040009_-	hypothetical protein	A0A090DCP2	Clostridium_phage	1.6e-74	99.3
AWH82160.1\|3040023_3041094_-\|tail	phage tail sheath protein	A0A090D804	Clostridium_phage	7.6e-190	100.0
AWH82161.1\|3041094_3041547_-	hypothetical protein	A0A090D829	Clostridium_phage	4.6e-80	100.0
AWH82162.1\|3041557_3041968_-	HK97 gp10 family phage protein	A0A090DBQ6	Clostridium_phage	1.5e-72	100.0
AWH82163.1\|3041968_3042319_-	hypothetical protein	A0A090EUC2	Clostridium_phage	9.8e-62	100.0
AWH82164.1\|3042320_3042671_-	hypothetical protein	A0A090DCN6	Clostridium_phage	1.8e-55	100.0
AWH82165.1\|3042699_3042921_-	transcription termination factor Rho	A0A090D801	Clostridium_phage	1.3e-30	100.0
AWH82166.1\|3042933_3043872_-	hypothetical protein	A0A090D825	Clostridium_phage	3.8e-177	100.0
AWH82167.1\|3043895_3044492_-	hypothetical protein	A0A090DBQ0	Clostridium_phage	4.2e-81	100.0
AWH82168.1\|3044612_3044843_-	hypothetical protein	A0A090EUB5	Clostridium_phage	7.2e-37	100.0
AWH82169.1\|3044884_3045079_-	hypothetical protein	A0A090DCN1	Clostridium_phage	7.9e-21	100.0
AWH82170.1\|3045797_3046838_-\|head	phage head morphogenesis protein	A0A090D822	Clostridium_phage	1.3e-194	100.0
AWH82171.1\|3046850_3048206_-\|portal	phage portal protein	A0A090DBP3	Clostridium_phage	5.8e-259	100.0
AWH82172.1\|3048220_3050617_-	hypothetical protein	A0A090EUA8	Clostridium_phage	0.0e+00	98.2
AWH82173.1\|3050606_3051059_-\|transposase	transposase	A0A090DCM3	Clostridium_phage	1.9e-81	100.0
AWH83335.1\|3051124_3051424_-	hypothetical protein	A0A090DC14	Clostridium_phage	2.9e-46	100.0
AWH82174.1\|3051731_3052676_-	DUF4868 domain-containing protein	Q24LC1	Clostridium_phage	1.9e-176	100.0
AWH82175.1\|3052781_3053099_+	hypothetical protein	A0A090DD01	Clostridium_phage	4.4e-53	100.0
AWH82176.1\|3053078_3053267_-	hypothetical protein	A0A0A8WIH0	Clostridium_phage	3.2e-27	100.0
AWH82177.1\|3053343_3053955_-	N-acetyltransferase	A0A0A8WFI2	Clostridium_phage	6.9e-111	100.0
AWH82178.1\|3053954_3054149_-	hypothetical protein	A0A090DC11	Clostridium_phage	5.7e-27	100.0
AWH82179.1\|3054875_3055364_-	hypothetical protein	A0A090EUN5	Clostridium_phage	6.1e-86	100.0
AWH82180.1\|3055457_3056183_-	phage antirepressor Ant	A0A090DCZ8	Clostridium_phage	1.3e-129	99.6
AWH82181.1\|3056197_3056605_-	RusA family crossover junction endodeoxyribonuclease	A0A0A8WIA1	Clostridium_phage	3.3e-61	85.9
AWH82182.1\|3056618_3057425_-	SAM-dependent methyltransferase	Q24LC8	Clostridium_phage	2.9e-157	99.6
AWH82183.1\|3057421_3057535_-	hypothetical protein	A0A0A8WF38	Clostridium_phage	2.3e-12	91.9
AWH82184.1\|3057553_3057802_-	hypothetical protein	Q24LC9	Clostridium_phage	1.4e-41	100.0
AWH82185.1\|3057806_3057992_-	hypothetical protein	Q24LD0	Clostridium_phage	5.4e-27	100.0
AWH82186.1\|3058070_3058538_-	hypothetical protein	Q24LD1	Clostridium_phage	4.8e-72	100.0
AWH82187.1\|3058540_3058912_-	hypothetical protein	Q24LD2	Clostridium_phage	9.1e-66	100.0
AWH82188.1\|3058904_3059078_-	hypothetical protein	Q24LD3	Clostridium_phage	1.3e-27	100.0
AWH82189.1\|3059074_3059800_-	reductase	Q24LD4	Clostridium_phage	2.4e-131	99.1
AWH82190.1\|3059808_3060804_-	nucleoid-associated protein	A0A090D855	Clostridium_phage	2.9e-151	81.7
AWH82191.1\|3060800_3061022_-	hypothetical protein	A0A0A8WJQ5	Clostridium_phage	1.2e-33	98.6
AWH82192.1\|3061039_3061735_-	hypothetical protein	NA	NA	NA	NA
AWH82193.1\|3061875_3062892_-	DNA (cytosine-5-)-methyltransferase	A0A0A8WFL3	Clostridium_phage	2.9e-199	99.7
AWH82194.1\|3062999_3063335_-	hypothetical protein	Q24LD9	Clostridium_phage	3.5e-56	100.0
AWH82195.1\|3063334_3063508_-	DUF3797 domain-containing protein	Q24LE0	Clostridium_phage	1.9e-29	100.0
AWH82196.1\|3063504_3063663_-	hypothetical protein	X5JB46	Clostridium_phage	3.9e-18	100.0
AWH83336.1\|3063637_3063784_-	hypothetical protein	X5JAX0	Clostridium_phage	4.7e-18	100.0
AWH82197.1\|3063767_3064148_-	hypothetical protein	X5JAK1	Clostridium_phage	5.7e-63	100.0
AWH83337.1\|3064151_3064502_-	hypothetical protein	X5JA06	Clostridium_phage	3.1e-63	99.1
AWH82198.1\|3064513_3064777_-	hypothetical protein	Q24LE3	Clostridium_phage	4.5e-43	98.9
AWH82199.1\|3064850_3065105_-	hypothetical protein	Q24LE4	Clostridium_phage	5.5e-46	100.0
AWH82200.1\|3065179_3065587_-	single-stranded DNA-binding protein	A0A0A8WIK6	Clostridium_phage	7.6e-74	100.0
AWH82201.1\|3065603_3065777_-	resolvase	A0A090EUJ6	Clostridium_phage	5.8e-23	100.0
AWH82202.1\|3065836_3066718_-	DnaD domain protein	Q24LE6	Clostridium_phage	5.2e-160	99.7
AWH82203.1\|3066727_3067336_-	recombinase	Q24LE7	Clostridium_phage	3.0e-106	100.0
AWH82204.1\|3067345_3067855_-	hypothetical protein	A0A0A8WJQ2	Clostridium_phage	2.7e-84	100.0
AWH82205.1\|3067937_3068183_-	hypothetical protein	X5JAW8	Clostridium_phage	1.7e-28	81.5
AWH82206.1\|3068172_3068355_-	hypothetical protein	NA	NA	NA	NA
AWH82207.1\|3068487_3068817_-	DNA-binding protein	A0A090D837	Clostridium_phage	1.6e-42	84.4
AWH82208.1\|3068833_3069031_-	XRE family transcriptional regulator	A0A090D859	Clostridium_phage	4.7e-29	96.9
AWH82209.1\|3069083_3069284_+	hypothetical protein	A0A090DBW4	Clostridium_phage	2.4e-28	98.5
AWH82210.1\|3069746_3070499_-	phage antirepressor Ant	A0A090D834	Clostridium_phage	2.1e-61	63.6
AWH82211.1\|3070491_3070671_-	hypothetical protein	A0A0A8WJW4	Clostridium_phage	2.9e-09	56.4
AWH82212.1\|3070806_3070986_+	Arc family DNA-binding protein	A0A0A8WG21	Clostridium_phage	5.1e-14	76.4
AWH82213.1\|3071172_3071961_-	phage regulatory protein	B6SBX3	Clostridium_virus	2.8e-120	87.0
AWH82214.1\|3072614_3072824_-	transcriptional regulator	A0A090DCT3	Clostridium_phage	6.3e-32	100.0
AWH82215.1\|3073000_3073396_+	XRE family transcriptional regulator	A0A090D830	Clostridium_phage	6.7e-67	100.0
AWH82216.1\|3074043_3074445_+	HicB family protein	A0A090DBV2	Clostridium_phage	7.0e-72	100.0
AWH82217.1\|3074503_3075622_+\|integrase	site-specific integrase	A0A090EUH1	Clostridium_phage	2.3e-205	100.0
AWH82218.1\|3075788_3076178_-	DUF1232 domain-containing protein	NA	NA	NA	NA
AWH82219.1\|3076281_3077283_-	aspartate--ammonia ligase	A0A1C9C5F0	Heterosigma_akashiwo_virus	1.8e-60	42.3
3083374:3083391	attR	NA	NA	NA	NA

DBSCAN-SWA_9

3176911 : 3185864

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWH82294.1\|3176911_3178825_-	polysaccharide biosynthesis protein	A0A1V0SAI8	Catovirus	1.1e-26	29.8
AWH82295.1\|3178908_3180000_-	glycosyltransferase family 4 protein	A0A1V0SL50	Klosneuvirus	2.3e-16	26.2
AWH83338.1\|3180005_3181301_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	4.9e-90	43.4
AWH82296.1\|3181326_3182079_-	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	4.6e-16	40.5
AWH82297.1\|3182126_3183035_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
AWH82298.1\|3183056_3183806_-	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	1.2e-16	38.8
AWH82299.1\|3183834_3185025_-	glycerophosphotransferase	NA	NA	NA	NA
AWH82300.1\|3185024_3185864_-	glycosyltransferase family 2 protein	A0A2P1ELT8	Moumouvirus	7.0e-05	26.3

DBSCAN-SWA_10

3627293 : 3663851

Clostridium_phage(79.49%)

capsid,holin,integrase,head,terminase,portal,plate,tail,protease

attL 3652169:3652186|attR 3672979:3672996

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWH82633.1\|3627293_3629321_-	SAM-dependent DNA methyltransferase	A0A220A2U5	Liberibacter_phage	2.6e-21	24.0
AWH82634.1\|3629782_3630262_+	hypothetical protein	NA	NA	NA	NA
AWH82635.1\|3630290_3631103_-	N-acetylmuramoyl-L-alanine amidase	X5JAJ5	Clostridium_phage	4.2e-148	93.3
AWH82636.1\|3631102_3631360_-\|holin	holin	A0A0K2SUI8	Clostridium_phage	2.0e-40	91.8
AWH82637.1\|3631379_3631610_-	hypothetical protein	A0A0A8WJR7	Clostridium_phage	2.8e-33	97.4
AWH82638.1\|3631680_3632214_-	hypothetical protein	A0A0A8WFF2	Clostridium_phage	1.7e-28	83.8
AWH82639.1\|3632247_3632430_-	hypothetical protein	J9QE73	Clostridium_phage	7.2e-24	95.0
AWH82640.1\|3632429_3632723_-	hypothetical protein	J9QE35	Clostridium_phage	2.7e-44	91.8
AWH82641.1\|3632736_3634434_-	hypothetical protein	A0A090EUF1	Clostridium_phage	1.7e-135	59.9
AWH82642.1\|3634450_3635452_-\|tail	phage tail protein	A0A1V0DZY8	Clostridioides_phage	6.4e-114	80.5
AWH82643.1\|3635453_3636071_-	DUF2313 domain-containing protein	J9QD29	Clostridium_phage	6.5e-101	87.8
AWH82644.1\|3636067_3637123_-\|plate	baseplate protein J	A0A0A8WFP3	Clostridium_phage	1.9e-185	94.3
AWH82645.1\|3637115_3637544_-	DUF2634 domain-containing protein	J9QE34	Clostridium_phage	2.0e-72	93.7
AWH82646.1\|3637543_3637870_-	DUF2577 domain-containing protein	J9QE86	Clostridium_phage	1.2e-48	90.7
AWH82647.1\|3637885_3639403_-	cell wall hydrolase	A0A0K2SUC1	Clostridium_phage	1.3e-254	88.6
AWH82648.1\|3639642_3640278_-	LysM peptidoglycan-binding domain-containing protein	J9QDY6	Clostridium_phage	1.6e-118	97.6
AWH82649.1\|3640277_3642032_-	hypothetical protein	A0A0K2SUF9	Clostridium_phage	2.4e-225	92.3
AWH82650.1\|3642215_3642599_-\|portal	phage portal protein	J9QED1	Clostridium_phage	6.8e-56	100.0
AWH82651.1\|3642647_3643097_-\|terminase	terminase	A0A0A8WF55	Clostridium_phage	1.4e-76	93.3
AWH82652.1\|3643109_3644177_-\|tail	phage tail sheath protein	J9QDY5	Clostridium_phage	4.6e-187	95.8
AWH82653.1\|3644191_3644608_-	hypothetical protein	A0A0K2SUF6	Clostridium_phage	1.1e-64	94.9
AWH82654.1\|3644619_3645033_-	hypothetical protein	A0A0K2SUA7	Clostridium_phage	2.2e-68	94.2
AWH82655.1\|3645025_3645364_-\|head,tail	head-tail adaptor protein	A0A0A8WI51	Clostridium_phage	9.8e-59	98.2
AWH82656.1\|3645365_3645653_-\|head,tail	phage gp6-like head-tail connector protein	A0A0A8WF50	Clostridium_phage	3.2e-42	95.8
AWH82657.1\|3645662_3646931_-\|capsid	phage major capsid protein	A0A0K2SUH4	Clostridium_phage	2.8e-231	97.9
AWH82658.1\|3646923_3647661_-\|protease	Clp protease ClpP	A0A0A8WFM9	Clostridium_phage	1.5e-123	88.6
AWH82659.1\|3647666_3648821_-\|portal	phage portal protein	J9QE83	Clostridium_phage	2.4e-205	93.5
AWH82660.1\|3648836_3650486_-\|terminase	terminase large subunit	A0A0A8WI49	Clostridium_phage	0.0e+00	94.9
AWH82661.1\|3650482_3650872_-	hypothetical protein	A0A090C9N7	Clostridium_phage	3.2e-61	100.0
AWH82662.1\|3650969_3651263_-	HNH endonuclease	J9QDZ3	Clostridium_phage	5.2e-48	91.8
AWH82663.1\|3651255_3651549_-	hypothetical protein	J9QE40	Clostridium_phage	8.3e-14	48.9
AWH82664.1\|3651745_3652345_-\|integrase	integrase	A0A0A8WF93	Clostridium_phage	6.8e-79	89.8
3652169:3652186	attL	NA	NA	NA	NA
AWH82665.1\|3652631_3653459_-	hypothetical protein	NA	NA	NA	NA
AWH82666.1\|3653830_3654343_-	transcriptional regulator	A0A1V0E028	Clostridioides_phage	3.6e-28	45.2
AWH82667.1\|3654528_3654822_-	hypothetical protein	NA	NA	NA	NA
AWH82668.1\|3654835_3655093_-	hypothetical protein	NA	NA	NA	NA
AWH82669.1\|3655082_3655712_-	RNA polymerase subunit sigma-70	NA	NA	NA	NA
AWH82670.1\|3655726_3657061_-	helicase	A0A222ZRG2	Mycobacterium_phage	7.2e-28	28.2
AWH82671.1\|3657075_3657840_-	hypothetical protein	B4XYS6	Lactobacillus_phage	8.0e-24	29.4
AWH82672.1\|3657863_3658094_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AWH82673.1\|3658105_3658543_-	XRE family transcriptional regulator	A0A1L2BY71	Clostridium_phage	1.3e-15	38.2
AWH82674.1\|3658570_3658789_-	transcriptional regulator	NA	NA	NA	NA
AWH82675.1\|3658953_3659301_+	XRE family transcriptional regulator	A0A090D830	Clostridium_phage	1.0e-10	34.8
AWH82676.1\|3659347_3660508_-	endonuclease	A0A1S5SAB0	Streptococcus_phage	3.2e-64	54.1
AWH82677.1\|3661261_3661483_+	XRE family transcriptional regulator	NA	NA	NA	NA
AWH82678.1\|3661530_3662709_+\|integrase	site-specific integrase	A0A1B0T6A8	Bacillus_phage	2.6e-37	31.0
AWH82679.1\|3663359_3663851_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	3.7e-38	54.5
3672979:3672996	attR	NA	NA	NA	NA

DBSCAN-SWA_11

3869599 : 3891058

Streptococcus_phage(91.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWH82851.1\|3869599_3869926_+	DUF961 domain-containing protein	A0A1S5SF38	Streptococcus_phage	2.0e-24	51.5
AWH82852.1\|3869941_3870325_+	DUF961 domain-containing protein	A0A1S5SF96	Streptococcus_phage	5.2e-32	57.6
AWH82853.1\|3870492_3870900_+	XRE family transcriptional regulator	A0A0A7AQV8	Bacillus_phage	1.2e-05	42.3
AWH82854.1\|3870915_3871242_+	hypothetical protein	NA	NA	NA	NA
AWH82855.1\|3871342_3872737_+	ATP-binding protein	A0A1S5SFB5	Streptococcus_phage	1.9e-177	66.2
AWH82856.1\|3872920_3874117_+	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	7.3e-149	62.5
AWH82857.1\|3874119_3874224_+	hypothetical protein	NA	NA	NA	NA
AWH82858.1\|3874264_3874486_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	9.0e-29	87.7
AWH82859.1\|3874689_3875466_+	XRE family transcriptional regulator	W6LMS6	Streptococcus_phage	4.9e-05	46.6
AWH82860.1\|3875550_3875847_+	conjugal transfer protein	NA	NA	NA	NA
AWH82861.1\|3875765_3876269_+	antirestriction protein	NA	NA	NA	NA
AWH82862.1\|3876286_3876790_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	3.4e-55	61.4
AWH82863.1\|3876907_3877306_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	3.2e-48	73.0
AWH82864.1\|3877283_3879734_+	ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	76.1
AWH82865.1\|3879733_3881929_+	MFS transporter	A0A1S5SF30	Streptococcus_phage	4.4e-176	68.6
AWH82866.1\|3881925_3882933_+	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	3.0e-135	69.9
AWH82867.1\|3882948_3883860_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.2e-82	52.8
AWH82868.1\|3883980_3884358_+	GntR family transcriptional regulator	NA	NA	NA	NA
AWH82869.1\|3884358_3885222_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.3e-18	30.2
AWH82870.1\|3885218_3885863_+	ABC-2 transporter permease	NA	NA	NA	NA
AWH82871.1\|3885875_3886067_+	nucleic acid-binding protein	NA	NA	NA	NA
AWH82872.1\|3886271_3886460_+	conjugal transfer protein	D0R0F6	Streptococcus_phage	8.2e-15	57.9
AWH82873.1\|3886567_3886927_-	XRE family transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	2.3e-21	45.0
AWH82874.1\|3887113_3887329_+	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	1.4e-31	98.6
AWH82875.1\|3887345_3887618_+	antitoxin	A0A1X9I6E5	Streptococcus_phage	5.0e-05	100.0
AWH82876.1\|3887619_3887778_+	zeta-toxin	NA	NA	NA	NA
AWH82877.1\|3888295_3889033_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	1.4e-134	99.6
AWH82878.1\|3889037_3889169_+	hypothetical protein	E4ZFP9	Streptococcus_phage	8.2e-14	90.7
AWH83360.1\|3889178_3889463_+	topoisomerase	A0A1X9I6W8	Streptococcus_phage	2.3e-40	93.0
AWH82879.1\|3889565_3890462_+	chromosome partitioning protein ParA	A0A1X9I765	Streptococcus_phage	5.1e-155	99.6
AWH82880.1\|3890553_3890769_+	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	4.2e-31	97.1
AWH82881.1\|3890785_3891058_+	antitoxin	A0A1X9I6E5	Streptococcus_phage	5.0e-05	100.0

Anti-CRISPR protein detection

Acr_ID: CP029154.1|AWH82214.1|3072614_3072824_-|transcriptional-regulator

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

CP029154.1|AWH82214.1|3072614_3072824_-|transcriptional-regulator

3072614_3072824_-

69 aa aa

HTH_XRE

Identity	Hit_domain_coverage
0.43103448275862066	1.0

3017468-3077283

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
CP029154_7	Orphan	7.9\|1688962\|36\|CP029154\|CRISPRCasFinder,CRT	1688962-1688997	36	3030658-3030623	1

1. spacer 7.9|1688962|36|CP029154|CRISPRCasFinder,CRT matches to CP029154 position: 3030658-3030623, mismatch: 1

tatatattagatgtcaatgtcaaggatacaaaattt	CRISPR spacer
tatatattagatgtcaatatcaaggatacaaaattt	Protospacer
******************.*****************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP029156

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP029155

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CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. CP029154

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information