CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
CP029363	Streptomyces globisporus strain TFH56 plasmid pTFSG2, complete sequence	0 crisprs	NA	0	0	0
CP029362	Streptomyces globisporus strain TFH56 plasmid pTFSG1, complete sequence	0 crisprs	NA	0	0	0
CP029361	Streptomyces globisporus strain TFH56 chromosome, complete genome	7 crisprs	csa3,DEDDh,DinG,cas3,c2c9_V-U4,WYL,cas4	2	9	2

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

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CRISPR-Cas detection and classification

Crispr_ID: CP029361_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029361_2

2329710-2329802

Orphan

Consensus_repeat	Method
TCCTCAAGCGCCGGACGGGCTTGAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029361_2

>merge|CP029361|2|2329710-2329802|CRISPRCasFinder
TCCTCAAGCGCCGGACGGGCTTGATTTTGCGCGGCCCGGCCGGCCCGCCCGGCGCCGGGAAAAAGATGTCCTCAATCGCCGGACGGGCTTGAT

>CP029361|2|2|2329710-2329802|CRISPRCasFinder
TCCTCAAGCGCCGGACGGGCTTGAT	TTTGCGCGGCCCGGCCGGCCCGCCCGGCGCCGGGAAAAAGATG
TCCTCAATCGCCGGACGGGCTTGAT

Protein	Signature genes	Signature genes Name	Protein_function
CP029361.1\|AWL86271.1\|2326826_2327639_+\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|236163
CP029361.1\|AWL86281.1\|2335333_2336329_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP029361.1\|AWL86275.1\|2329887_2330673_-\|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl\|CDD\|224527
CP029361.1\|AWL86280.1\|2334895_2335216_-\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|224069
CP029361.1\|AWL86274.1\|2328782_2329655_+\|dihydropteroate-synthase	unknown	unknown	gnl\|CDD\|273657
CP029361.1\|AWL90351.1\|2324604_2325294_-\|RNA-polymerase-sigma-factor-SigE	unknown	unknown	gnl\|CDD\|236606
CP029361.1\|AWL86273.1\|2328239_2328695_-\|cell-division-protein-DivIVA	unknown	unknown	unknown
CP029361.1\|AWL86267.1\|2321462_2323445_-\|PDZ-domain-containing-protein	unknown	unknown	gnl\|CDD\|273938
CP029361.1\|AWL86269.1\|2325543_2326209_+\|O-methyltransferase	unknown	unknown	gnl\|CDD\|226607
CP029361.1\|AWL86270.1\|2326342_2326510_-\|DUF3117-domain-containing-protein	unknown	unknown	gnl\|CDD\|371461
CP029361.1\|AWL86279.1\|2333690_2334785_-\|succinyldiaminopimelate-transaminase	unknown	unknown	gnl\|CDD\|236119
CP029361.1\|AWL86282.1\|2336399_2337281_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372582
CP029361.1\|AWL86277.1\|2331967_2332834_+\|hypothetical-protein	unknown	unknown	unknown
CP029361.1\|AWL86284.1\|2338157_2340014_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
CP029361.1\|AWL86272.1\|2327646_2328243_-\|DNA-3-methyladenine-glycosylase-I	unknown	unknown	gnl\|CDD\|377025
CP029361.1\|AWL86266.1\|2320830_2321331_-\|Sec-independent-protein-translocase-TatB	unknown	unknown	gnl\|CDD\|179287
CP029361.1\|AWL86283.1\|2337583_2338189_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|225107
CP029361.1\|AWL86278.1\|2333124_2333592_+\|ATP-binding-protein	unknown	unknown	unknown
CP029361.1\|AWL86268.1\|2323537_2324608_-\|zf-HC2-domain-containing-protein	unknown	unknown	gnl\|CDD\|379219
CP029361.1\|AWL86276.1\|2330766_2331846_-\|succinyl-diaminopimelate-desuccinylase	unknown	unknown	gnl\|CDD\|237264

Protein	Function_ID	Function_description	E-value
CP029361.1\|AWL86271.1\|2326826_2327639_+\|enoyl-CoA-hydratase	gnl\|CDD\|236163	PRK08140, PRK08140, enoyl-CoA hydratase; Provisional.	5.33892e-73
CP029361.1\|AWL86281.1\|2335333_2336329_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.38315e-10
CP029361.1\|AWL86276.1\|2330766_2331846_-\|succinyl-diaminopimelate-desuccinylase	gnl\|CDD\|237264	PRK13007, PRK13007, succinyl-diaminopimelate desuccinylase; Reviewed.	0
CP029361.1\|AWL86280.1\|2334895_2335216_-\|ferredoxin-family-protein	gnl\|CDD\|224069	COG1146, COG1146, Ferredoxin [Energy production and conversion].	1.44531e-11
CP029361.1\|AWL86269.1\|2325543_2326209_+\|O-methyltransferase	gnl\|CDD\|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	7.57847e-46
CP029361.1\|AWL90351.1\|2324604_2325294_-\|RNA-polymerase-sigma-factor-SigE	gnl\|CDD\|236606	PRK09647, PRK09647, RNA polymerase sigma factor SigE; Reviewed.	1.31656e-126
CP029361.1\|AWL86267.1\|2321462_2323445_-\|PDZ-domain-containing-protein	gnl\|CDD\|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	3.08067e-89
CP029361.1\|AWL86274.1\|2328782_2329655_+\|dihydropteroate-synthase	gnl\|CDD\|273657	TIGR01496, Dihydropteroate_synthase, dihydropteroate synthase. This model represents dihydropteroate synthase, the enzyme that catalyzes the second to last step in folic acid biosynthesis. The gene is usually designated folP (folic acid biosynthsis) or sul (sulfanilamide resistance). This model represents one branch of the family of pterin-binding enzymes (pfam00809) and of a cluster of dihydropteroate synthase and related enzymes (COG0294). Other members of pfam00809 and COG0294 are represented by model TIGR00284. [Biosynthesis of cofactors, prosthetic groups, and carriers, Folic acid].	6.76982e-91
CP029361.1\|AWL86270.1\|2326342_2326510_-\|DUF3117-domain-containing-protein	gnl\|CDD\|371461	pfam11314, DUF3117, Protein of unknown function (DUF3117). This family of proteins with unknown function appears to be restricted to Actinobacteria.	3.05791e-23
CP029361.1\|AWL86282.1\|2336399_2337281_+\|hypothetical-protein	gnl\|CDD\|372582	pfam13369, Transglut_core2, Transglutaminase-like superfamily.	4.07032e-39
CP029361.1\|AWL86284.1\|2338157_2340014_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.12912e-68
CP029361.1\|AWL86272.1\|2327646_2328243_-\|DNA-3-methyladenine-glycosylase-I	gnl\|CDD\|377025	pfam03352, Adenine_glyco, Methyladenine glycosylase. The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA.	1.0779e-99
CP029361.1\|AWL86266.1\|2320830_2321331_-\|Sec-independent-protein-translocase-TatB	gnl\|CDD\|179287	PRK01371, PRK01371, Sec-independent protein translocase protein TatB.	3.47423e-52
CP029361.1\|AWL86283.1\|2337583_2338189_+\|DNA-binding-response-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.02127e-32
CP029361.1\|AWL86279.1\|2333690_2334785_-\|succinyldiaminopimelate-transaminase	gnl\|CDD\|236119	PRK07865, PRK07865, N-succinyldiaminopimelate aminotransferase; Reviewed.	0
CP029361.1\|AWL86268.1\|2323537_2324608_-\|zf-HC2-domain-containing-protein	gnl\|CDD\|379219	pfam13490, zf-HC2, Putative zinc-finger. This is a putative zinc-finger found in some anti-sigma factor proteins.	5.16485e-07
CP029361.1\|AWL86275.1\|2329887_2330673_-\|TIGR00730-family-Rossman-fold-protein	gnl\|CDD\|224527	COG1611, COG1611, Predicted Rossmann fold nucleotide-binding protein [General function prediction only].	1.33593e-53

>CP029361.1|AWL86274.1|2328782_2329655_+|dihydropteroate-synthase
MRSGALRLGRREFGPHEPVIMAIVNRTPDSFYDQGATFRDEPALARVEQAVAEGAAIIDIGGVKAGPGEEVTAEEEARRTVGFVAEVRRRHPDVVISVDTWRHDVGAAVCEAGADVLNDAWGGVDPKLAEVAARYGAGLVCTHAGGAEPRTRPHRIAYDDVMADILRVTVGLAERAVELGVRPDGIMIDPGHDFGKNTRHSLEATRRLEEMAGTGWPVLVSLSNKDFVGETLDRPVKERVIGTLATTAVSAWLGARVYRVHEVAETRQVLDMVASIAGHRPPAVARRGLA
>CP029361.1|AWL86273.1|2328239_2328695_-|cell-division-protein-DivIVA
MARSEPDEVSAPGEMRVFWFLLLTMVVVVTAVTLAVVGGGGSAVLQDVPPERFTDPLPAARPVGRADVEALRLPMALRGYRMVDVDEALSRLGAELAERDARIAELESTLAGDRAAAVTTGADLFKQPGDRPAAEPADRADGADGTEEDGR
>CP029361.1|AWL86272.1|2327646_2328243_-|DNA-3-methyladenine-glycosylase-I
MSGGAVAAPDGKPRCPWGLSTEDYLAYHDTEWGRPVHGDDALFERLCLEAFQSGLSWLTILRRRETFRTAFEGFRIEAVAKFTGTDRERLLADPGIIRNKAKVDATLANAKVLAGWPAGELDELIWSYAPDPAGRPAPRTLSDVPAVTPESTALAKELKKRSIRFVGPTTAYALMQACGLVDDHLADCVARGGGSASS
>CP029361.1|AWL86271.1|2326826_2327639_+|enoyl-CoA-hydratase
MADEQANTVLYDVSEGLATITLNRPDAMNALSTAAKVALRDALLEASADPEVRAVLLTATGRAFCVGQDLKEHIATLAATRDAGGGNALSTVREHYNPIVRAITEMAKPVVAGVNGVAAGAGFGFALAADYRVVADTASFNTSFAGVALTADSGVSWTLPRLIGQSRAADLLLFPRSISAQDALELGIVNRVVPADELPEQAAAVARTLAAGPTVAYAALKESMAYGAGHTLAETLEKEDELQTRAGASQDHTIAVEAFLAKEKPVYLGK
>CP029361.1|AWL86270.1|2326342_2326510_-|DUF3117-domain-containing-protein
MAAMKPRTGDGPLEVTKEGRGIVMRVPLEGGGRLVVELTPDEADALGDALKKVVG
>CP029361.1|AWL86269.1|2325543_2326209_+|O-methyltransferase
MRQLRGQERVITANRQTSWAFADAFVAEDEALHVARERARELGLRPVSPGTGAALRLLAAAADAKAVAEIGTGTGVSGIYLLHGMRPDGVLTTVDPEPERQQFAREAFRAAGFATNRARFIPGRALDVLPRLADGGYDLVFCDGDRLESLDVLAESLRLLRPGGLVCFEGVFADGRTVDSAAQPAEVLRLRELLRAARESQELMSTLLPVGDGLLCAVRRG
>CP029361.1|AWL90351.1|2324604_2325294_-|RNA-polymerase-sigma-factor-SigE
MLRRLLRSAGEPKSVTNIADRSSEDSAPTATFASDADSQAWTPPSWEEIVSTHSGRVYRLAYRLTGNQHDAEDLTQEVFVRVFRSLSTYTPGTFEGWLHRITTNLFLDMVRRKQRIRFDSLGDDAAERLPSREPSPQQIFNDTHFDADVQQALDTLAPEFRAAVVLCDIEGLSYEEIAATLGVKLGTVRSRIHRGRSHLRKALKHRSPEARAEQRSLADAVLAGEGGLA
>CP029361.1|AWL86268.1|2323537_2324608_-|zf-HC2-domain-containing-protein
MSGTGPTGPTPAEAHLGDRLAALVDGELKHDARERVLAHLATCAKCKAEADAQRRLKSAFAMSASPSPSEGFLARLQGLPGGPGGDGTGSGGPFGGRGPFADEFFPGLRPSGADTRADTAPSPLDGFGYLPATHGSPAVLRGGAASGSAFRIHEVGREADRSPWRGRRFAFAAASAVSLAAIALGGTLPLDSGPESSLRAEGAGNNVTPLDAETRAENGATAVSRRGGGALAVTGDGRAAEQPGTGSAGTGTKAVPPSLTGTTPVVPVVTPPVNRQGPPTAPPLFGASASGGHPFMLPVLNVSVPPLIRPAASGTPLLAAALGSGAVPKTVPSSLPSEPPPGSPANDLASPLSPRP
>CP029361.1|AWL86267.1|2321462_2323445_-|PDZ-domain-containing-protein
MDDGKPTGPQAKWWSRPTARRADHPEPVGGPAPTGAPEPEGPARASAVPDQAPTPAPSSPAPVAPDSASASAAAAEVRESAPAAPDQAPPAPVPAAQDQAPAPAARGQVSAPGSPSAAADEPGGQEIPRPRPSGQPLHEPDEYSTPPYGGPGPWAPAPPVQRPTPAHGTVVPPGAGGPTPQYPATNGAGIPAPAPHPAPTDGHTPPHAQPAGGFAAPQPGPTDAFPPPHPAPIDTYAPPPQAHANAQQPAHSAPGQQHQQTQWLQYDPWGAPGQPFTRPGPPEGAEPGRKKKRRGGAFVGVLLLALVASGIGGGVGAYIERNGGLTTVELPQAGRDNGDRAPDSVAGIAASALPSVVTLHVSGTAESGTGTGFVLDGQGHILTNNHVVAPAGSSGDITVTFSTGETASAELVGKDSGYDLAVVRVRGVSGLKPLPLGNSDNVRVGDPVVAIGAPFDLSNTVTSGIISAKQRPITAGGEKGDGSDISYVDALQTDAPINPGNSGGPLVDSKAHVIGINSAIRAADSGGGPESGGQSGSIGLGFAIPINQGKRVAEELISTGKATHPVIGVTLDMKYTGDGAKVGTKDADGGPAVAKDGPADKAGIKSGDVITQVEGQRVHSGEELIVKIRAHRPGDDLDLKLTRGGEERTVTLKLGSASGT
>CP029361.1|AWL86266.1|2320830_2321331_-|Sec-independent-protein-translocase-TatB
MFNDIGALELLTLGVLAVLVFGPDKLPKLIQDVTRTIRKIREFSDSAKEDIRTELGPQFKDFEFEDLNPKTFVRKQLMDGNDDLGLKEIRESFDLRKDLADVTDAVNGRTPAASDTANSAANGSAGASAGAPSTSLTKTGDTAPDLLKKAPSPAQPERPPFDSDAT
>CP029361.1|AWL86275.1|2329887_2330673_-|TIGR00730-family-Rossman-fold-protein
MGNAEDARIPEGAEVPEGAVSPGEQWLGPVLRRREQVQPGTTDQRLLDSEGDSEWVHTDPWRVMRIQSEFVEGFGALAELPSAISVFGSARTPAGSPEYEAGVAIGKALVDAGFAVITGGGPGAMEAANKGARESKGVSVGLGIELPFESGLNPHVDIGVNFRYFFVRKTMFVKYAQGFVVLPGGLGTLDELFEALTLVQTGKVTRFPIVLFGTAYWGGLIDWLRDTVVAQGKASEKDLLLFHVTDDVEEAVMLVTKEVGR
>CP029361.1|AWL86276.1|2330766_2331846_-|succinyl-diaminopimelate-desuccinylase
MADSTLDLTLDGPALTARLVDFPSVSGEEKALADAIESALRALPHLTVDRYGNNVVARTNLGRAERVVLAGHIDTVPIADNVPSRLDADGILWGCGTSDMKSGVAVQLRIAATVPAPNRDLTFIFYDNEEVAAHLNGLGHIADAHPEWLAGDFAVLLEPSDGEVEGGCQGTLRVHLRTAGERAHSARSWMGSNAVHAAAPILAALAAYEPRRPVIDGLEYHEGLNAVGIEGGVATNVIPDACTVVVNYRYAPDRTEEEAVAHVREVFADCGVAEIVIDDHSGAAMPGLSHPAAQAFMTAVGGTARPKFGWTDVSRFGGLGVPAVNYGPGDPMYAHKRDEHVAVDKITHCEERLRSWLTD
>CP029361.1|AWL86277.1|2331967_2332834_+|hypothetical-protein
MLAALGGYLAVQYDSSGSKNPPRCVVEAKDGDEGETQRYEMSLAQAVNAATISAVGTTRGMPERAVTIALATALQESTLRNIDYGDRDSLGLFQQRPSQGWGKPAQLMDPVYSAGEFYDHLAEVPGYSRLPLTVAAQRVQRSGFPQAYAKHEPDAALLAAALTGRRPASLNCTPSTATAEGPGDAGQVRAELVRAFGKDVLPTAKAAGASAASTVSVPVPATSARAEDKASPRRGWELAHWAVAQSEALRIERVSYADRVWDAGTGWRTEDAKGEETGTTAVRIQVVQ
>CP029361.1|AWL86278.1|2333124_2333592_+|ATP-binding-protein
MSLPLTRRIARAALLIAAGATPVVGAAGAASAADLPAAPELGGLTALDGANVGNTLDSTAQQGTQAAGETGGRLVGTALPAAGETVGKSAKVAVPAAQETAGQAAGNAGEAVGGVADAAGGGLPTDGLGGGLPTDSLGKGGLPTDALPLNGLPIG
>CP029361.1|AWL86279.1|2333690_2334785_-|succinyldiaminopimelate-transaminase
MSAVSSRLPVFPWDKLAPYKSTAQAHPDGIVDLSVGTPVDPVPELIQRALVAAADSPGYPTVWGTEALRDALTGWVERRLGAAGVTHANVLPVVGSKELVAWLPTQLGLGTGDRVAYPRLAYPTYEVGARLCGAEPVVYDDPTELDPAGLKLLWLNSPSNPTGKVLSKDELTRIVAWAREHGVLVFSDECYLELGWDAEPVSVLHPDVCGGHYDGIVAVHSLSKRSNLAGYRAAFIAGDAAVLGELLLIRKHGGMMTAAPVQAATVAALGDDVHVSEQRARYADRRLALRAALEAHGFRIEHSEASLYLWASRDEPCWDTVAYLAERGILVAPGDFYGPAGASFVRVAFTATDERVAAAVKRLS
>CP029361.1|AWL86280.1|2334895_2335216_-|ferredoxin-family-protein
MTYVIAQPCVDVKDKACIEECPVDCIYEGQRSLYIHPDECVDCGACEPVCPVEAIFYEDDTPEEWKDYYKANVEFFDDLGSPGGASKLGLIERDHAFVAGLPPQNQ
>CP029361.1|AWL86281.1|2335333_2336329_+|GNAT-family-N-acetyltransferase
MEFTIGGRLEVRITPADVGKRVSVRRRTDSGGTGAEFTDVVGVLTSWNDGVVSITRKSGESVHIVESSLVAGKVVPAAPARRRGPAASFEELAAVTARAWQPVESEALGDWRLRAAGGFTRRANSVLPLGDPGLPLGEAFGRVRRWYEERGLPAYVQTATGAEGTQELLCAELEEHGWRCEVSAEVRIASLTPVGDREAEVSAVRLTREPDAAWLARYQRFSTPGPHVLRVLGSGPSVWFATVPGSGDAPDAIGRCVVDGRWAGFMAVEVAPEQRRRGLATTVMTALARRALDEGASAAWLQVEEDNEGARALYDGMGFAGHHRYHHYRSA
>CP029361.1|AWL86282.1|2336399_2337281_+|hypothetical-protein
MSGLDSGAAERRRQFAEEARSERPDLALLCLLLGAEAGPVGPAEVVPVTPGEPVPDPYGIDAAQIELDRLAGLLPYGSRSPAGWASALAELLGERCGFGGSSADYQRLDSSLLQQVLRRRRGLPILLSVVWIEVARRAGAPVYGVALPGHFVVGFGDREHPVLADPFAGGAPLTGQDAELLVTGATGAALEPSMMVPARPLEIVLRILNNIRAWAAARPERTDVALWAVELSLLLPSHPARLRYEHAQLLVQRGEFLRGAAEMEEYAAILAEIEPTTAENIRRKAHAARALLN
>CP029361.1|AWL86283.1|2337583_2338189_+|DNA-binding-response-regulator
MTTVLLVHTVPLWRASLASLLGTGQGIEVRTAERGAIRAALSGGCPDVLLTDLDCPGARDVLDEVRTVTAPHGGTYPLAVLTRSDQPRGLRRAYEAGALGYIDKYRPVDDLSEVMHKLADGGRHIDESLAFSLLQVADMPLSPRELSVLSMAEEGDNVAGIAARLHLTPGTVRNYLAAAIRKSGARNRLDAIRRAKEAGWI
>CP029361.1|AWL86284.1|2338157_2340014_-|ABC-transporter-ATP-binding-protein
MKPGHDPAHPPRDTALRRVAREARPFLRARTGAILRLSGWSLLEFAQTFLSGYGVARALDDGFLAGRPATGLLWLAVAAVAVLPSVLAARGVFGRLADLVEPLRDGLVRRAVARALSGALGRSGDVSTRSLSQVTHQSEIARDGWAGLVLTLRSFVFTAAGAVTGLLALSPALLLIVLPPLVLGAALFLGTLPPMAARQRAYLAADEAYAAHAGELAASVRDIAAAGTAGRTVAESRALADAQLAASRSLARWSAVRVVALAVCGRFPPLLLLLGAPWLLRNGLTPGGLVGALTYLTQALAPAVQALMTMLGTAGGRLVVVLDRFTDAPPPPADEPAREAAPPASRSAAREATPVAELHEVTFAYGPRAHPVLDRLSLAVGAGEHLAVVGPSGSGKSTLAAVLAGTERPTGGAVRWRGRPARPADATSVRVLLPQHAYVFSGSLRDNLRYLRPDARDREIAAMADAVGLEALLSRLGSLDTAVEPDRLSQGERQLVALGRAYLAAPPLLILDEATSRLDPAAETRAELAFATLPGALVVVAHRLSSARRADRTLVMDGPRTRCGTPAELLRSSALYRDLSGLWEPEEADTVPEPEAPEEAPRRGEERAIRSTPPPSPV

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Crispr_ID: CP029361_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029361_3

2963768-2963862

Orphan

Consensus_repeat	Method
AAGGGTTCCGTCCTCAATCGCCGGACGGGCTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029361_3

>merge|CP029361|3|2963768-2963862|CRISPRCasFinder
AAGGGTTCCGTCCTCAATCGCCGGACGGGCTGGAATCACGCAGCCTCGCCGCCCTCCCGAGGAAGGGTTCCGTCCTCAAACGCCGGACGGGCTGG

>CP029361|3|3|2963768-2963862|CRISPRCasFinder
AAGGGTTCCGTCCTCAATCGCCGGACGGGCTGG	AATCACGCAGCCTCGCCGCCCTCCCGAGG
AAGGGTTCCGTCCTCAAACGCCGGACGGGCTGG

Protein	Signature genes	Signature genes Name	Protein_function
CP029361.1\|AWL86791.1\|2968483_2968969_-\|nitroreductase-family-deazaflavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|281995
CP029361.1\|AWL86789.1\|2966544_2967354_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319911
CP029361.1\|AWL90400.1\|2971518_2971899_-\|twitching-motility-protein-PilT	unknown	unknown	gnl\|CDD\|350299
CP029361.1\|AWL86788.1\|2963066_2963753_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223021
CP029361.1\|AWL86792.1\|2968965_2970171_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
CP029361.1\|AWL90398.1\|2963920_2966332_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
CP029361.1\|AWL86795.1\|2973030_2973939_+\|zinc-metalloprotease-HtpX	unknown	unknown	gnl\|CDD\|179418
CP029361.1\|AWL86780.1\|2952346_2953567_-\|amidohydrolase	unknown	unknown	gnl\|CDD\|368185
CP029361.1\|AWL86781.1\|2957336_2957615_+\|hypothetical-protein	unknown	unknown	unknown
CP029361.1\|AWL86790.1\|2967725_2968373_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
CP029361.1\|AWL86785.1\|2959916_2961065_+\|lipid-transfer-protein	unknown	unknown	gnl\|CDD\|181147
CP029361.1\|AWL90399.1\|2971915_2972194_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|376852
CP029361.1\|AWL86793.1\|2970333_2971506_+\|acetyl-CoA-acetyltransferase	unknown	unknown	gnl\|CDD\|180434
CP029361.1\|AWL86786.1\|2961539_2962316_+\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|119339
CP029361.1\|AWL90397.1\|2961080_2961536_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224462
CP029361.1\|AWL86784.1\|2958248_2959817_-\|fatty-acid--CoA-ligase-family-protein	unknown	unknown	gnl\|CDD\|236072
CP029361.1\|AWL86783.1\|2958037_2958223_-\|hypothetical-protein	unknown	unknown	unknown
CP029361.1\|AWL86787.1\|2962332_2962869_-\|hypothetical-protein	unknown	unknown	unknown
CP029361.1\|AWL86794.1\|2972264_2972951_+\|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl\|CDD\|273138
CP029361.1\|AWL86782.1\|2957611_2958010_+\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|350222

Protein	Function_ID	Function_description	E-value
CP029361.1\|AWL86791.1\|2968483_2968969_-\|nitroreductase-family-deazaflavin-dependent-oxidoreductase	gnl\|CDD\|281995	pfam04075, F420H2_quin_red, F420H(2)-dependent quinone reductase. This family of proteins is found in the genera Mycobacterium and Streptomyces. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. Rv1558 is an F420H(2)-dependent quinone reductase involved in oxidative stress protection.	1.08435e-17
CP029361.1\|AWL86789.1\|2966544_2967354_-\|VOC-family-protein	gnl\|CDD\|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	2.34867e-26
CP029361.1\|AWL86792.1\|2968965_2970171_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	2.27818e-38
CP029361.1\|AWL90398.1\|2963920_2966332_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.81371e-74
CP029361.1\|AWL86795.1\|2973030_2973939_+\|zinc-metalloprotease-HtpX	gnl\|CDD\|179418	PRK02391, PRK02391, heat shock protein HtpX; Provisional.	7.3786e-174
CP029361.1\|AWL86780.1\|2952346_2953567_-\|amidohydrolase	gnl\|CDD\|368185	pfam04909, Amidohydro_2, Amidohydrolase. These proteins are amidohydrolases that are related to pfam01979.	3.02617e-30
CP029361.1\|AWL86788.1\|2963066_2963753_+\|hypothetical-protein	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	0.00521305
CP029361.1\|AWL86790.1\|2967725_2968373_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.86316e-09
CP029361.1\|AWL86785.1\|2959916_2961065_+\|lipid-transfer-protein	gnl\|CDD\|181147	PRK07855, PRK07855, lipid-transfer protein; Provisional.	0
CP029361.1\|AWL90399.1\|2971915_2972194_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	2.10243e-06
CP029361.1\|AWL86793.1\|2970333_2971506_+\|acetyl-CoA-acetyltransferase	gnl\|CDD\|180434	PRK06158, PRK06158, thiolase; Provisional.	6.32946e-132
CP029361.1\|AWL86786.1\|2961539_2962316_+\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|119339	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.	7.42184e-36
CP029361.1\|AWL90397.1\|2961080_2961536_+\|hypothetical-protein	gnl\|CDD\|224462	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only].	7.25749e-20
CP029361.1\|AWL86784.1\|2958248_2959817_-\|fatty-acid--CoA-ligase-family-protein	gnl\|CDD\|236072	PRK07656, PRK07656, long-chain-fatty-acid--CoA ligase; Validated.	0
CP029361.1\|AWL90400.1\|2971518_2971899_-\|twitching-motility-protein-PilT	gnl\|CDD\|350299	cd18732, PIN_MtVapC4-C5_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 toxin of the VapBC toxin/antitoxin (TA) system. This family belongs to the PIN_VapC4-5_FitB-like subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. M. tuberculosis VapC4 interacts with, and cleaves tRNA44Cys-GCA. M. tuberculosis VapC5 has endonucleolytic activity with RNA, this activity is low with dsRNA, and no activity has been demonstrated on dsDNA. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.37612e-40
CP029361.1\|AWL86794.1\|2972264_2972951_+\|pyridoxamine-5'-phosphate-oxidase	gnl\|CDD\|273138	TIGR00558, Pyridoxine/pyridoxamine_5'-phosphate_oxidase, pyridoxamine-phosphate oxidase. This model is similar to Pyridox_oxidase from Pfam but is designed to find only true pyridoxamine-phosphate oxidase and to ignore the related protein PhzG involved in phenazine biosynthesis. This protein from E. coli was characterized as a homodimer with two FMN per dimer. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine].	1.05812e-56
CP029361.1\|AWL86782.1\|2957611_2958010_+\|DNA-binding-protein	gnl\|CDD\|350222	cd09874, PIN_MT3492-like, VapC-like PIN domain of the hypothetical protein MT3492 of Mycobacterium tuberculosis CDC1551 and other uncharacterized, annotated PilT protein domain proteins. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis CDC1551, hypothetical protein MT3492, and similar bacterial and archaeal proteins are included in this subfamily. They are PIN domain homologs of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.73614e-06

>CP029361.1|AWL86788.1|2963066_2963753_+|hypothetical-protein
MIRNILGSVVALAGAASAVLSPFRDWYGGRAGHDYRVRDLFEGITPVESGVLVSILLPFLAAALLVVLGVVLRSRLVVALAGLVVLGFTILWMVRQGQAAGSLVVGGDGAGLQVGVVNALAGGVLMLIGALLMSGRRSRRERRVVREREPVEPFAVPAADQVDTWPPTQEPGMSVQTSPWPEPEVEPYTGPDPRDARTRSYPQAAPHPEDDPRDPVHPPHRPPPPPQG
>CP029361.1|AWL86787.1|2962332_2962869_-|hypothetical-protein
MMRRQMKLAAVLVVVVLALTGFSTSSSGGKGRSGKSSSSDGGGCSSSKKSNNGYRDTDYDDDDYGDSSSSSGSSGASPTPTPTASDEALDIRVIRCAAPRKGKRKAVTSSLIEVQANDRYTQDYEIDVRFVDARGNTVDTAEATTTLDSGDFTTLTVRMDSPGKVSRVDRCEVTAKVV
>CP029361.1|AWL86786.1|2961539_2962316_+|enoyl-CoA-hydratase/isomerase-family-protein
MALRIEREAAAGVVLVTLDRPAKLNAIDLETAAELASLWQELRYDESIRAAVLTGAGTRAFCTGIDRGIEVPQPSSPYAVDDPLLRIGPKANDLWKPVIAAVEGMACGGAFYLLGEAEFVVASREATFFDPHTTYGMVSAYEAIAMAQRMPYGEVARMSLMGTAERVSAERAYAVGLVSEVTEPGGTVAAALRSAAVIAGYPTDAVQGTVRAVWSAKEAARTQAMAQAPALIALGNLPPDRQAELFGARGGGGEPRVR
>CP029361.1|AWL90397.1|2961080_2961536_+|hypothetical-protein
MSDADSLLLPVVDEDGAPFWEYTARGELRVQACASPACGELRFPPRPCCPHCGSFTSEWRLMSGRGRLWSYVIPHPPLLPAYAEQAPYNAVLVELADAPQIRLAGNVVASPDAPLNSVDPARLRIGAPVRAAFCPAGPSGSVTLVRWLLER
>CP029361.1|AWL86785.1|2959916_2961065_+|lipid-transfer-protein
MATLKDATAIAGIGQTAFAKRLPESEKTLACRAILAALDDAGIAPSEVDGFASYTMEETDEVEVAKAVGAGDVTFFSKVGYGGGGSCATLGHLAAAIATGQASVGVAWRSRKRGSGPRPWKNTTVQLPTPAQWTRPYGLLRPADEIGMLARRYMHEYGATRDHLFNVALACRNRANQNPDAIMYDRPLTREMYMTSRWISEPLCLFDNCLETDGALACVIVSAERARDCRQKPVYLHSVAQGLPAQHHGMVNYWNDDPLTGPAWAAARQLWKQADFGPDDVHVAQIYDAFTPLVPLSLEGYGFCARGEGGAFTEGGALESGGRLPVNTGGGGLSEAYVHGFNLITEGVKQLRGTSTAQVPDAATCLVTAGEGVPTSAVLLRS
>CP029361.1|AWL86784.1|2958248_2959817_-|fatty-acid--CoA-ligase-family-protein
MRGDEEWGSIPGLVRAAAERYGPAEAVADGRTRLSYAELGDRVERAAAACMAAGVEPGDRVAIWAPNTTEWIVAALGAVSAGAVLVPLNTRFKGTEAAYILRRSRARLLFVTGTFLGTSYVASLRRAEVKLPDLERVVVLADTAPEDYTGWPDFLAAGEGVEPSAVRDRGAAIAPSSPSDIIYTSGTTGAPKGAVITHAQTLRAYEIWSDLAGLREGDRYLIVNPFFHTFGYKAGIIACLMRGATMVPQPVFNVDTVLANIAAERISVLPGPPTLHQSLLDHPAREAHDLSALRLVVTGAAVVPLQLVERLRNELHIATVLTAYGLSEASGIVTMCRRGDAPETVATTSGRAIPGTEIRVLADPGAPGEVQVRGFTVMSGYFEDPDTTAATMTEDGWLRTGDVGVLDAAGNLRITDRIKDMFIVGGFNAYPAEIEQLLGLHPDVADVAVIGVPDPRLGEVGKAYAVRRRGATLTADDLIAWSRREMANFKVPRTVEFVPELPRNASGKVVKGELRGSPDGRK
>CP029361.1|AWL86783.1|2958037_2958223_-|hypothetical-protein
MVVRMPTKKYTVTLPEKPAEETLAEVGPGGLSAYATRVVERRREQDRPGELVAPVGGPGRE
>CP029361.1|AWL86782.1|2957611_2958010_+|DNA-binding-protein
MSGALVLDSEGLAQAVRRNREVQEWLEAARDADIPVITSAVVLVEVIHPRIDSAALSWTLSRLRVEPVSQILAHTAASLLRNAGLHGHEYAIDALLCATALAHPGRVTILTSDVEDIGLLTADHPRVTAEKI
>CP029361.1|AWL86781.1|2957336_2957615_+|hypothetical-protein
MAEAPDFPPGDGPSSGISVSLTAGTLHAIRERVGKRGVSAYLEMAAQRQIERDGLNELLADFEATNGPPDPGAVADKRAKLTSNPSEAGAAG
>CP029361.1|AWL86780.1|2952346_2953567_-|amidohydrolase
METFPKIISVDDHTVEPAHVWRDRLPSRYADSGPRIVRAPLKEMTFLGGKFAPVMGAKGDDGPVGDWWVYEDLHRPLTRLDTAVGYDRDEIKLEIITYEQMRPGSFSVPDRLADMDVNHVQSALCFPTFPRFCGQTFTEAKDRELGLLGVRAYNDWMVEEWCGPEARGRLIPLTLIPLWDAELAAAEVRRNAARGVRAVAFSEIPPHLGLPSIHADDWDPLLAACDETGTVIAMHIGSSSRMPSTSADAPPAVGSTITFANCCFSMVDWLMSGKFERFPNLKIMYAEGQIGWIPYILERADVVWEENRAWGGVADKVHRPPSELFAEHVYGCFFDDAFGLKNLDAIGLGNVLYETDYPHSDSTWPRSREVGEEQMGHLAPDVVDRIVRGNAIELLGLTEDGLWAGP
>CP029361.1|AWL90398.1|2963920_2966332_-|serine/threonine-protein-kinase
MEQLTQHDPRRIGPFEVLGRLGAGGMGLVYLARSASGRRVAIKTVRTELAEDQLFRVRFTREVEAARAVSGFYTAAVVDADPRAAVPWLATAYVPAPSLEEIVNECGPMPTQAVRWLAAGIAEALQSIHGAGLVHRDMKPSNVLVVEDGPRVIDFGIASGVSNTRLTMTNVAVGTPAYMSPEQARDSRSVTGASDIFSLGSTLVFAATGHAPFHGANPVETVFMLLREGPDLEGLPDDLRPLIESCMQMDATQRPSPADLQAQLAPHLFASGGDDSGTASAWLPSRATAMIEARRGGGRTAPPAAPVSPPPPPRQPPRAPERDTAWRSGADLRSPSPLASPSPMSGGPAPSAGPSAAPDSGPVRLPGAKVPIGPGPRAGDGRGAAAAHPAPATGWVRPPAGVNGSPATAAVPPPGPAPDAAAPAPDRWRPWRFRMSNDVWGTPVVSGDLLYVTSFEVHALDVGNGRRQFKTRDVAWAMAVEGGRIHASDGPSLYALDATTGAEQWRLSTDAWVYALKADRGTVLTATRGGGVQGWEASSGEKLWEVTGAQSDFETAEAGPVIHDGTVYVWQDARLRALDARTGLERWSYPIGDAASCGGVPVRVTPATDGYVYIAAGTRVLAVETGSGRVRWHFEAPAVFLSPPAFAPGPAVTGGGVYLADYLGTVYALDATTGKDRWRIATEARSSIEPVLVAVGNVHVGSGSALYTLDAVTGTPKWRFAAGGDVVGAPVVADGRVHFGSADHVLYTLDAAGGQLRWKLATGGEITGSPVAQGGVVYACSKDRCVYALDALKGTGTGNRART
>CP029361.1|AWL86789.1|2966544_2967354_-|VOC-family-protein
MAAFAHSAPCWADVQLSDLEAGKRFYGGLFGWTFRAGDGMPVADALSDGRLVAALAAKKDGRMPTAWGVYFSTDDIRATVASIREHGGQIITDPVRAGAAGIVAEAADPGGAVFGLWQPEERAGFEKQNDPGSFCWTEVYTRQPDRVDPFYEKVFGFHGTDLDETGHDVSDDAEALVDFRMWSPEGVEPGPDTAVGGRSVITDAFPAEMPSYFLIYFAVADCDAAAELAVQLGGRVAQPPFDIPYGRMAVLHDDQGAAFAVLQPGELLP
>CP029361.1|AWL86790.1|2967725_2968373_+|TetR/AcrR-family-transcriptional-regulator
MTGQVRTVDGRVAGRRGQATRQKLLDCLSEMLSSSPYRDVKVIDVARKAGTSPATFYQYFPDVEGAVLEIAEEVAKEGAGLTELVAGRSWVGKAGWTTSEQLVEGFLDFWRHNDAILRVIDLGAAEGDKRFYKIRMKILNSVTNSLTDSVKELQSKGKVDKDVSPAAMAGSLVAMLAAVASHQKGFTTWGVKQAELRPNLALLVHLGITGKKPTK
>CP029361.1|AWL86791.1|2968483_2968969_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase
MTGARGARLVQRVSSTRAFALFAPYVVPVLDRAVHRLTRGRVLLSARMLPGLVLTVPGARTGRPRTTPLACMPEGEVEGSWILVGSNFGRPGHPAWTANLLARGGEAVVNWRGRDIPVRATLLEGEERARVWEAALAFWPPYAAYQRRVERQIRLFRLERR
>CP029361.1|AWL86792.1|2968965_2970171_-|acyl-CoA-dehydrogenase
MDTALTAEQHEIRRTLRDLLARHTGPDAIPAAVGTAEGYDPALWRRLAGDLGLPGLALGEEYGGAGCTATELALACEETGRALLPSPLLATAALAAPLIAALGTPDQRAALLPRIADGTLTAALALPGGSLATALGLTGDNLDGTWAGGGRAGGVQAHGEAGERRLYGEADRVLDGHSAGLLLVAAHAGGYPRSRTQLFLVPGDAPHLVRTRLTALDETRPLARVELRDTPAELLGPDDTADAAAALADAGRTAAAILAAEAVGTAASALERTVEYVKTREQFGRAVGSFQAVKHRLADLYVRVEAARSAAYHAAREPEAGPLALAQALEAARVTTGEAVQLHGGIGFTWEHEAHRYLKRAAGDELLFGPVHRLRDHAAHRAGLFGPATAASGVLHGAGVR
>CP029361.1|AWL86793.1|2970333_2971506_+|acetyl-CoA-acetyltransferase
MSASRPRRVAVVGVALADCGRVDDATPYALHAQAARRALADSGLDRSVVDGFASAGLGTLAPVEVAEYLGLRPTWVDSTAVGGATWEVMAAHAADAIAAGRARAVLLVYGSTARADIRAGRRTSNLSFGARGPAQFEVSYGHSLIAKYAMAARRHMHAYGTTLEQLAEVAVTARANAAANPEAMFREPITVEDVLSGPMIADPFTKLHCCIRSDGGCAVLLAAEEYVPDTAKAPVWILGTGEHTSHATMSEWEDFTVSPAAVSGRLAFERAGVRPADIDLAEIYDAFTYMTLVTLEDLGFCAKGEGGAFVEKGRTGLRGELPVNTDGGGLSACHPGMRGLFLLVEAVRQLRGEAGLRQVIRAGGGLPELAVASGTGGWFCSSGTVVLGRG
>CP029361.1|AWL90400.1|2971518_2971899_-|twitching-motility-protein-PilT
MLDTCTYIDLDLLEPERLPMLPALTAISLAELQHGVAMAKDPLVRAARMEKLGAAVADFEPLPFDGDAAARYGTLVALVLAARRDPRPRRMDLMIASIASVRGLPLFTRNADDFKGLESAVTVVGL
>CP029361.1|AWL90399.1|2971915_2972194_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MKTITQREFRNNSAEVMDAVESGETFHITRNGTEVAELRPLSRKRQLSAEELVARHRRLPRVDGDLLRREADEFFGAEDRVGDDDVWERNGG
>CP029361.1|AWL86794.1|2972264_2972951_+|pyridoxamine-5'-phosphate-oxidase
MTDDTAQRSFRDLLHAQRVWDTELPAFDPETAPPAPLTLFHAWFAEAVAAGQPEPHAMALATADAEGLPDVRTLLLHDADERGLHFASHATSAKGHQLAARPHAALGFYWPAQGRQVRVRGPVVRCTPAESHADLHARSTGALAAALTGTQSEVVGSVAELHRTADAARDRAMAEPDAEAPTWTRYVVEPTEVEFFQGDARRRHIRLRYRRAEGGGTDGDWTRELLWP
>CP029361.1|AWL86795.1|2973030_2973939_+|zinc-metalloprotease-HtpX
MPRARSRYAPDRGLTGRMVTTMFLIGLLYVVFVGVLLAALRGSWPIILIITGGMFIAQFWFSDRIAAYGMGAREVTPEQAPELHGTIDRICALADMPKPKVAIAESDVPNAFATGRSEKTALVCATTGLLRRLEPEELEGVLAHEMSHVAHRDVAVMTIASFLGVLAGIITRIALWGGFARSRPGNDPAGILLLLIPLISAVVYAISFLLTRLLSRYRELSADRAAALLTGRPSALASALTKVSGQMARIPTEDLRKAEPYNAFYFMPAFSAKESLGRLFSSHPTLEQRLDQLSRISTELSR

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Crispr_ID: CP029361_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029361_4

3184736-3184898

Orphan

Consensus_repeat	Method
CGTACGGCGGGCCTCCGCC	CRT

3 spacers

The CRISPR arrays of CP029361_4

>merge|CP029361|4|3184736-3184898|CRT
GGTACGGCGGGCCTCCGCCTGAAGCAGGTCCGGCCCCGCGCAGCCGTACGGCGGGCCTCCGCCCGAAGCGAGGCCGCCCCGGGGTCCGGCCCCGCGCACGCGTACGGCGGGCCCCCACCCGAAGCTGGTCCGGCCCCGCGCGAACGTACGGCGGGCCTCCGCC

>CP029361|4|1|3184736-3184898|CRT
GGTACGGCGGGCCTCCGCC	TGAAGCAGGTCCGGCCCCGCGCAGC
CGTACGGCGGGCCTCCGCC	CGAAGCGAGGCCGCCCCGGGGTCCGGCCCCGCGCACG
CGTACGGCGGGCCCCCACC	CGAAGCTGGTCCGGCCCCGCGCGAA
CGTACGGCGGGCCTCCGCC

Protein	Signature genes	Signature genes Name	Protein_function
CP029361.1\|AWL86975.1\|3180115_3180565_+\|response-regulator	unknown	unknown	gnl\|CDD\|381108
CP029361.1\|AWL86971.1\|3175100_3176654_+\|PTS-alpha-glucoside-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|181971
CP029361.1\|AWL86976.1\|3180530_3182942_-\|histidine-kinase	unknown	unknown	gnl\|CDD\|226702
CP029361.1\|AWL86980.1\|3188019_3189324_+\|sugar-binding-protein	unknown	unknown	gnl\|CDD\|270303
CP029361.1\|AWL90416.1\|3198186_3198816_+\|hypothetical-protein	unknown	unknown	unknown
CP029361.1\|AWL86970.1\|3174074_3175055_+\|N-acetylmuramic-acid-6-phosphate-etherase	unknown	unknown	gnl\|CDD\|235467
CP029361.1\|AWL86981.1\|3189455_3190436_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
CP029361.1\|AWL86987.1\|3196994_3197438_-\|ketosteroid-isomerase	unknown	unknown	gnl\|CDD\|226158
CP029361.1\|AWL86973.1\|3177474_3178086_-\|Uma2-family-endonuclease	unknown	unknown	gnl\|CDD\|99749
CP029361.1\|AWL86972.1\|3176841_3177462_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|224996
CP029361.1\|AWL86984.1\|3194077_3194503_+\|hypothetical-protein	unknown	unknown	unknown
CP029361.1\|AWL86982.1\|3190432_3191347_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
CP029361.1\|AWL86974.1\|3178316_3180119_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369272
CP029361.1\|AWL86969.1\|3173092_3174010_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
CP029361.1\|AWL86977.1\|3183118_3183472_+\|PRC-barrel-domain-containing-protein	unknown	unknown	unknown
CP029361.1\|AWL86986.1\|3194726_3195209_+\|hypothetical-protein	unknown	unknown	unknown
CP029361.1\|AWL86985.1\|3194502_3194730_+\|hypothetical-protein	unknown	unknown	unknown
CP029361.1\|AWL86979.1\|3184958_3187784_-\|glycoside-hydrolase	unknown	unknown	gnl\|CDD\|227785
CP029361.1\|AWL86968.1\|3172592_3172964_-\|hypothetical-protein	unknown	unknown	unknown
CP029361.1\|AWL86983.1\|3193399_3193972_+\|DUF417-domain-containing-protein	unknown	unknown	gnl\|CDD\|225601

Protein	Function_ID	Function_description	E-value
CP029361.1\|AWL86975.1\|3180115_3180565_+\|response-regulator	gnl\|CDD\|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	8.06579e-35
CP029361.1\|AWL86971.1\|3175100_3176654_+\|PTS-alpha-glucoside-transporter-subunit-IIA	gnl\|CDD\|181971	PRK09586, murP, PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed.	6.20274e-116
CP029361.1\|AWL86976.1\|3180530_3182942_-\|histidine-kinase	gnl\|CDD\|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	0
CP029361.1\|AWL86980.1\|3188019_3189324_+\|sugar-binding-protein	gnl\|CDD\|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.5459e-33
CP029361.1\|AWL86970.1\|3174074_3175055_+\|N-acetylmuramic-acid-6-phosphate-etherase	gnl\|CDD\|235467	PRK05441, murQ, N-acetylmuramic acid-6-phosphate etherase; Reviewed.	3.16315e-158
CP029361.1\|AWL86982.1\|3190432_3191347_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	6.87467e-85
CP029361.1\|AWL86981.1\|3189455_3190436_+\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	3.49019e-82
CP029361.1\|AWL86973.1\|3177474_3178086_-\|Uma2-family-endonuclease	gnl\|CDD\|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	4.45535e-24
CP029361.1\|AWL86972.1\|3176841_3177462_+\|oxidoreductase	gnl\|CDD\|224996	COG2085, COG2085, Predicted dinucleotide-binding enzymes [General function prediction only].	8.90296e-20
CP029361.1\|AWL86974.1\|3178316_3180119_+\|hypothetical-protein	gnl\|CDD\|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	4.61435e-40
CP029361.1\|AWL86969.1\|3173092_3174010_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	2.25767e-66
CP029361.1\|AWL86987.1\|3196994_3197438_-\|ketosteroid-isomerase	gnl\|CDD\|226158	COG3631, COG3631, Ketosteroid isomerase-related protein [General function prediction only].	5.21094e-08
CP029361.1\|AWL86979.1\|3184958_3187784_-\|glycoside-hydrolase	gnl\|CDD\|227785	COG5498, ACF2, Predicted glycosyl hydrolase [Cell envelope biogenesis, outer membrane].	1.56515e-79
CP029361.1\|AWL86983.1\|3193399_3193972_+\|DUF417-domain-containing-protein	gnl\|CDD\|225601	COG3059, COG3059, Predicted membrane protein [Function unknown].	9.74449e-07

>CP029361.1|AWL86977.1|3183118_3183472_+|PRC-barrel-domain-containing-protein
MSDSLWGYQPSSGHTAGVDLTGYSVEATDGSIGKVDKYSDEVGSAYLLVDIGVWIFGKDVLLPAGTVKRIDTEDRKVYVDLTKEQVKDSPEFDRHQQTEDPAYHEQLSAYYTAYRIL
>CP029361.1|AWL86976.1|3180530_3182942_-|histidine-kinase
MPDDVQGWLTPRAVAAEAGVSQEFDLSQCVREPIHLLGGVQSYGALIAARWDDAAVDTVSENAAEVLGRAAGELLGRPVTELIGDEQWAQARESAEAVTDSGAAAPQEGPASSGVLPLTLEGEGGPRLFDVTVHRNGDLLVLEFEPRAEGGPFVFQNFYPRVRRALQKLQGATDVTECCAAAVREIRTLTGYDRVVAYRFDGRDGPGQVIAEDRSEGREPWLDLWFPASDIPPQARRLYARNWIRVIGDVADRTAGLVPERRADTGEPLDLSASVLRTVSGYHLEYLRNIGVASSMSVSLLHEGDLWGLIACHGDEPRRLSPEVRAACEFFGIALSLQLAAVAGREEADELARSRRALASVLARLTSGAPDDWMRPGSGLVELLDADGAVLLRGTETLTAGAPLPDALPGLPARLAQDGSVRGVWSSDRLPEVLGLEPEEAEAEGIPAGLLLLPFNRDGDLLAWWRREQPAPREWAADPSRPVRTGPGGERLTPRGSAAVYRATVRGRSAPWSPAQRAVAGELWREVSGLLTRQVVALEARNTELARTNEDLDSFAHAAAHDLKEPLRGISNAAAFIVEDAGTVLDATSLRRLTTVRRLAERMDGLLDSLLHFSRLGQVGLEREALSVDEVLDDALVVAGGRLAEQGVTLVRPAALPRLRADRERLREVLENLLVNAAKYAADEGAGERRVWVEAVRVAAPGRAPEEGGADGGTVTALVVRDNGIGIPPGQQEDVLQLFRRLHRRDERGGGSGVGLAVVKRIVERHGGRLWLESPAVAPDADCGGGPGTAVWFTLEEPPEARP
>CP029361.1|AWL86975.1|3180115_3180565_+|response-regulator
MTGGGLILVVEDSEEDTEAIQRALSRSHPFLDLEFAPRSEDVLPRLLDPAARTPDLVLLDLNMPGIGGLALLSSLRAHPACASLTVVVFTSSTASAEEDSCYAAGADSYIYKPVNFELFQTVLRGAVDFWLPRAADGAVTAVPPAAPPA
>CP029361.1|AWL86974.1|3178316_3180119_+|hypothetical-protein
MVDDDTWSGALHRLWQAASRAEEVGALADDVYAPLLATPGVHLVVGTRWDEDATLRYMRALGADGDAPVIVATARSMPGAAVREPDGEPVVTRSPVDELDDAVWPEAEFLRQVPGASVVGCTFRLDRSGWAGLSVAMDTSADTEGVARRLAQAVDVIVACHTGILQRGREARRGADDALLAEASLQMDSSLDVEDTLRRVARIAVPAVADGCLVHLLRKDGPEFVAATHVAVQQQRALEEAGRDDPWLAALLAQRDDGDQALFLSGAALDGSPFAGPGPTGGGRHPTVVSVSTLHARGRVVGSITFVYQRPEDRLPDSAFLDSLATRAALAIDNALLYELRRHAVLSLQEHLLPSQLPAAAGWDLSASYEVGDPMLDVGGDFYDAVPRPDGSIALLIGDVCGRGAEAAALTGLARHTLRTLLEEGTDPGTALSRLNRALRQEGASRFLTAVVVTMTPRADGTVLLTTCSAGHPRPLVLRADGSIGEVVSGGLLLGILDDVSYESHEDSLAPGDTLVLFTDGLTESREADGTYFESVLPGRLSALRGSDAAQVAESLARQARAFRASGQDDIALLVARWNGITPSDGLLPLETWLEQAALR
>CP029361.1|AWL86973.1|3177474_3178086_-|Uma2-family-endonuclease
MTAAFVENGQASDGRAWDYLLQTWRELDVPEGWRAEIDEGQIVLVPPPHAHHNGIAARVQRKLYTTLPEDLEIYQTLGIHIAPLGKLYVPDLVVMPTELIAAADPETSDPMDASEALLVVEITSRGNAREDRTKKYRAYARAGVPMYLLIDRFDTRGPMVTLFTEPNEDGTYKHTDAVPFGKPLTVPSPFDVQLATEEFPGAS
>CP029361.1|AWL86972.1|3176841_3177462_+|oxidoreductase
MRIGLLGTGNVARALATGWRAAGHDVLLGSRHPKERTDLGLPVAGLDGTAAHAEVLVNATPGGVSVDLLRSIGAPALAGTLLIDVGVGLSDDFSALTHPNSSLGELIQEAFPLTPVVKTLCTMDSTTMVAPGELTEPGTVFLSGEDPEAKATTGRLLTDLGWPAASQLDIGGITTARGQEHFAFLFMGIAGGVNSHTFNIKVVTRP
>CP029361.1|AWL86971.1|3175100_3176654_+|PTS-alpha-glucoside-transporter-subunit-IIA
MATEDKNRATAAAILPLVGGAANVASIAHCMTRLRLGLHDRSLVDDEALKALPAVMGVVEDDTYQIVLGPGTVARVTPEFEQLVEEGRETAPTPVTVSADDLAAQGAAIKAQQKAKNATPFKLFLRKIANIFVPLIPALIGCGIIAGLNGLLVNLGWLPAVTPALAAMASGFMALIAVFVGYNTAKEFGGTPILGGAVAAIIVFPGVANIDAFGQTLSPGQGGVLGALGAAVLAVYVEKWCRRWVPEALDVLVTPTLTVLISGLVTIFGLMFVAGEISSAIGTFADWLLSNGGAGAGFVLGGLFLPLVMLGLHQALIPIHTTLIEQQGYTVLLPILAMAGAGQVGAAMAVYFRFPRNESIRRTIKSALPAGLLGVGEPLIYGVSLPLGRPFITACVGGAFGGGFVGLFNQLGDTVGSTAIGPSGWALFPLLDGNHGLGSTIAIYAGGLLVGYVAGFVATYFFGFSKDLLTEFNVSQEPTASTIAATGGAAPSTTPPAAGGPDTPDPGTDPAKAPAGV
>CP029361.1|AWL86970.1|3174074_3175055_+|N-acetylmuramic-acid-6-phosphate-etherase
MTSTTDANTDTPGATGTPGTYGELRAQLATLTTEAFRPELAEIDRLSTEEIARIMNGEDATVPAAVAARLPQIAAAIDATAERMARGGRLIYAGAGTAGRLGVLDASECPPTFNTDPAEVVGLIAGGPSAMVTAVEGAEDSKELAAADLDALKLTADDTVVGISASGRTPYAIGAVEHARAQGALTIGLSCNADSALAAAAEHGLEVVTGPELLTGSTRLKAGTAQKLVLNMISTVTMIRLGKTYGNLMVDVRASNEKLRARSRHIVSLATGASDAAIEAALAATDGEVKNAILVVLGQVDGPTAARLLTESDGHLRAALAAVRTT
>CP029361.1|AWL86969.1|3173092_3174010_+|MurR/RpiR-family-transcriptional-regulator
MTSDVKEIFSSGSPPAPAALAAKVRTLAPSMTRSMQLVAEAVAGDPAGCAALTVTGLAERTGTSEATVVRTARLLGYPGYRDLRLALAGLAAHQESGRAPAVTADIAVDDPIADVVAKLAYDEQQTLADTAAGLDTVQLGAAVAAASTARRIDIYGVGASSLVGQDLAQKLLRIGLIAHAHMDPHLAVTNAVQLRSGDVAIAITHSGSTGDVIEPLRVAFDRGATTIAITGRPDGPVSQYADHVLTTSTARESELRPAAMSSRTSQLLVVDCLFIGVAQRTYETAAPALAASYEALAHRHTPRTR
>CP029361.1|AWL86968.1|3172592_3172964_-|hypothetical-protein
MELNALEQSLHTARALVMADLAAADVAEADIVSLVEDAVTHRRWWVEQWPEGAEFVAGLVAQDVQDALLERYGRWPLCPACSPEDEPHALDVEPELGPDPHWVCTKAAVAVAPVGALGEVLRR
>CP029361.1|AWL86979.1|3184958_3187784_-|glycoside-hydrolase
MIEVLLVLTSLSGLVSRVTPRPAAATLLAIAVAAVGLGPAASPAAAATIPAGAGSYTDARPAGTQGPTTNTGAPVTPKLTTAARSKPVPTNDWWSSLAFQRYGDNPYSTPMYGHPLTYQAKASGLEVGYPTTPAIVGDGRQYEYAHKADLTVGLSGLNSPDTKADAWSDWTVTPYWADGSRTFRATIGHGMPFVYAKGSGGDARITTASAPTVFSDQGNVLGITVAGHHYALFAPTGSDWNISGSTITAGLGSKDYFSLAVLPSTDALATYRKYAFSFVTGSQVAWQTTGGNVRATYSLTTEAKEGTERGTLQALYRHQWLHTSDALTPYTYVSPRGTMKVRESATFTTSQKNNGVVPALPASSGVDKARLTGYLNEVANASDPFSGATDTYWTGKALGRLAQLVPVADQIGQTATRDKLLGLMKGRLQEWFTAGGASEFSYDKDWKTLTGYPASYGSDTELNDHHFHYSYYVYAAAIIAQYDQAWVADSAWGTMIKHLIRDTANASRTDSAYPFLRGFDVYAGHSWASGHQGFAAGNNQESSSESINLSAALVLFGSATGDNALRDLGSYLLTTESEAITQYWFDASQQVFPASFGHDTVGMVWGSGGAYSTWWTANPEEIHGINVLPVTGGSLHLAREKAAIKRNIAEMERENGGPAQEWRDLLWEFESLSDPASAKAKWDGVNGNYTPEQGESKAHTYHWINTLAAVGAPDMTVSGDIPTSAVFSKNGTRTYTAHNHGSTARTVTFSDGKTLSVPARSTATSTGPGGSDPDPEEPGEPGNGNTFRLKTGGVLTTATTDPAGADTIASADGVNRDGTPYRPTVYEVKKVNGKVTAGAATAFRLRVDAGTKVGLAPQVRVSYDLTGDGTFDRIETFRYFATDPVAGWEEYTQAVGAQATTGSLGELKNGTVRLEIWNALGNGTSQVQTGTDAAVLRIPYQ
>CP029361.1|AWL86980.1|3188019_3189324_+|sugar-binding-protein
MPIARAAKRATARLGAVVLAGALLAACGSSDSSDSSDSAGGKVTLNVDLFGSFGFKEAGLYEEYQKLNPNITIKQSDTQDEADYWKSLQTRLAGGGGLADVQGVEVGRIASVTQQQSDKFQDLKEFGADKLKGEFAEAKWSAATTKDGKILGLGTDVGPEAMCYRTDLFKQAGLPTDREELAKKWATWDGYLELGKEYKKKAPAKSAWLDSVGSLHGIMIGQEKERYYDASGELIYDKNPAVKEAWDTSVEAAEAGLSAKLDQWSPQWNQAFSAGSFATIPCPAWMLGYVKGQAGDAGKGKWDIAKLPGGAGNWGGSYLSIPRAAKHKEEAYKLIEWLTAPEQQAKVFQKQGNFPSSTGAIETIAGAKDEYFSGAPIGQIFGDAAKESPVQVLGVHDQNVMQQITNALSEVERKGVSSDKAWGTAKKGVDNVIG
>CP029361.1|AWL86981.1|3189455_3190436_+|sugar-ABC-transporter-permease
MSLTATAKAGPRSPAGTGPGPDDGRAAALRRTWRKASPYAYIAPFFTLFLAFGLFPLVYTAFVSLYRVELQTSGEMEWRGIANYTALFTDEYFWTSLRNTFTIGVLSTVPQLAMALGLAHLLNYKLRGRTFIRTAILLPYATSVAAATLVFAQLFGKDFGLINYAIGLVGFDPVDWQTGTVASQIAVSSIVVWRWTGYNALIYLAGMQSIPHELYEAAEMDGASRWRQFVHVTLPGLRPTIVFTVIISTIGATQLFGEPLLFEGSISGGISHQYQTLGLYMYEQGWGFFHLGRAAAIAWVMFVLIVVLVGVNALIARRRARKEAGR
>CP029361.1|AWL86982.1|3190432_3191347_+|carbohydrate-ABC-transporter-permease
MTALAAPPTAPEKGDPPQTPPPGRRIGKGGAGRTMKGGWLSYLILGFALLISAFPFYWTIVAASRSNADMAKVPPSLLPGPNLIKNFEQVLEEADIGKALLNSLIVSGSITIGTVLCCTLAGFAFAKLKFKGRNALLTLTIGTMMIPPQLGVIPLFMLIAELQWVNQLQAVILPGLVSAFGVFFMRQYLVQSLPDELIEAARVDGASTARIFWSIVIPIARPGMAVLGMLTFMTAWNDFFWPIIALSSQEPTVQVALRQLGGGYVNDQSVIMAGTLLGTLPVLLVFGLLGRQIVGGIMQGAVKG
>CP029361.1|AWL86983.1|3193399_3193972_+|DUF417-domain-containing-protein
MSSHTVEPSLPPTSGNPESPLAGTQLERTARPPAARFPRRLAELVDTHALTLLRATVGIVFVGFGVLKLFPSASPAEQLAVDAATKMTLGLVPETVLLLSLAALETAIGIGLITGRRLLRPALVAFFLHMGGVFSTLFLLPDAMWQPHSPAPTMEGQYVVKNVVLVAVCLVVAAHEWSREHRSRRPDGVG
>CP029361.1|AWL86984.1|3194077_3194503_+|hypothetical-protein
MTKEPAAGTGDEPLPFAPLPPGARGPLDPPPLETPPPGFGPRLVIAEGVLTKAAGAADKVFDDFHKPARSVDEPTGKAARELAGWESAAALRTSLKNWQNQSKAAETWLIRIAESLRSSSHAYTSTSQTVDQQFSVLRTYG
>CP029361.1|AWL86985.1|3194502_3194730_+|hypothetical-protein
MPAFYRELLDTDLSVLDALADTWRDAHTATEKLPKRMMDDVLRPLRDKGYWEGAAAPHARSLIDWTERIPSGRDK
>CP029361.1|AWL86986.1|3194726_3195209_+|hypothetical-protein
MTGAGRPTVRHLAAASALAAVSLSLTTGCSDAALCGPPPLDEVSQMDLYGTYAGPHGSRLTLTNIGGTTVTFTARDWPAENGVGILAEDAPSFDGEGTWSLVNDPGEAGLIRLSFENRDAGSSGTPLQQLEVGKGEGDAKPLLFAKLGDPDACRVYELER
>CP029361.1|AWL86987.1|3196994_3197438_-|ketosteroid-isomerase
MSIATPANTRTVVEELLRRIGEGNPERIAEMYAEQGDWKLDWPEAEHGRTATPWIRHRSTRADAAAHYRELAEHHVPEHVATEVERILVDGSDAVVLGEIRQTARPTGRAYKARFALHITVADGLVTRHHVYEDSLAIAQAFEAKDQ
>CP029361.1|AWL90416.1|3198186_3198816_+|hypothetical-protein
MTEHGGAADQPQNTPRSRLADYAEMSGPGRSVPASREAVGETAGGGGEPAPLARQEPALEAPSAEVDDPGALLDDPEVVSRKREFARLLGEFRRTAVLVPLGDEPGPEEERGMLTADFNGIRFILAFSDEQALARYAQARGEFAREWSYRTVLGARLLDVAVPAAAVPCGVALDCADGTDGMVFPPVTGIVPDAAAVDREVGGEARVGR

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Crispr_ID: CP029361_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029361_6

3784146-3784251

Orphan

Consensus_repeat	Method
CCAGCCCGTCCGGCGCGTGAGGACGGAACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029361_6

>merge|CP029361|6|3784146-3784251|CRISPRCasFinder
CCAGCCCGTCCGGCGCGTGAGGACGGAACCCTTGCGGTGGTGGGCCCGCGCTTGCTGTGGGCCGGGGCCCGGCGAACCAGCCCGTCCGGCGCTTGAGGACGGAACC

>CP029361|6|5|3784146-3784251|CRISPRCasFinder
CCAGCCCGTCCGGCGCGTGAGGACGGAACC	CTTGCGGTGGTGGGCCCGCGCTTGCTGTGGGCCGGGGCCCGGCGAA
CCAGCCCGTCCGGCGCTTGAGGACGGAACC

Protein	Signature genes	Signature genes Name	Protein_function
CP029361.1\|AWL87452.1\|3784306_3786424_-\|phosphatase	unknown	unknown	gnl\|CDD\|369272
CP029361.1\|AWL87453.1\|3786589_3788383_+\|aspartate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234775
CP029361.1\|AWL87461.1\|3797691_3797937_-\|DUF2630-domain-containing-protein	unknown	unknown	gnl\|CDD\|378515
CP029361.1\|AWL87446.1\|3775756_3777574_+\|alkyl-hydroperoxide-reductase	unknown	unknown	gnl\|CDD\|271321
CP029361.1\|AWL87456.1\|3791270_3791948_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|223816
CP029361.1\|AWL87454.1\|3788620_3789412_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226309
CP029361.1\|AWL87443.1\|3773299_3774124_-\|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl\|CDD\|274422
CP029361.1\|AWL87450.1\|3782039_3782996_+\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
CP029361.1\|AWL87442.1\|3771945_3773253_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
CP029361.1\|AWL87455.1\|3789498_3791112_-\|methionine--tRNA-ligase	unknown	unknown	gnl\|CDD\|237012
CP029361.1\|AWL87460.1\|3797244_3797646_+\|RNA-binding-protein	unknown	unknown	gnl\|CDD\|224109
CP029361.1\|AWL87445.1\|3775200_3775692_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227231
CP029361.1\|AWL87458.1\|3793149_3794739_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378410
CP029361.1\|AWL87459.1\|3795033_3797103_+\|PhoX-family-protein	unknown	unknown	gnl\|CDD\|253386
CP029361.1\|AWL87447.1\|3777621_3777843_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376437
CP029361.1\|AWL87448.1\|3779398_3781225_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173842
CP029361.1\|AWL90461.1\|3777946_3779245_-\|M18-family-aminopeptidase	unknown	unknown	gnl\|CDD\|235073
CP029361.1\|AWL87449.1\|3781393_3781861_+\|SseB-family-protein	unknown	unknown	gnl\|CDD\|377787
CP029361.1\|AWL87444.1\|3774325_3775117_+\|carbon-nitrogen-family-hydrolase	unknown	unknown	gnl\|CDD\|143607
CP029361.1\|AWL87457.1\|3791944_3793216_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223715

Protein	Function_ID	Function_description	E-value
CP029361.1\|AWL87452.1\|3784306_3786424_-\|phosphatase	gnl\|CDD\|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	8.9573e-52
CP029361.1\|AWL87453.1\|3786589_3788383_+\|aspartate--tRNA-ligase	gnl\|CDD\|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
CP029361.1\|AWL87461.1\|3797691_3797937_-\|DUF2630-domain-containing-protein	gnl\|CDD\|378515	pfam10944, DUF2630, Protein of unknown function (DUF2630). This bacterial family of proteins have no known function.	1.19441e-31
CP029361.1\|AWL87446.1\|3775756_3777574_+\|alkyl-hydroperoxide-reductase	gnl\|CDD\|271321	cd14951, NHL-2_like, NHL repeat domain of NHL repeat-containing protein 2 and similar proteins. NHL repeat-containing protein 2 (NHLRC2) and related bacterial proteins; members of this eukaryotic and bacterial family are uncharacterized, the NHL repeat domain is found C-terminally of a thioredoxin domain. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.	6.44684e-165
CP029361.1\|AWL87456.1\|3791270_3791948_+\|DNA-binding-response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.42248e-65
CP029361.1\|AWL87454.1\|3788620_3789412_+\|hypothetical-protein	gnl\|CDD\|226309	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown].	4.68794e-12
CP029361.1\|AWL87443.1\|3773299_3774124_-\|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl\|CDD\|274422	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083. This protein family pulls together several groups of proteins, each very different from the others. They share in common three conserved regions. The first is a region of about 38 amino acids, nearly always at the N-terminus of a protein. This region has a bulky hydrophobic residue, usually Trp, at position 29, and a His residue at position 37 that is invariant, so far, in over 150 instances. The second conserved region has a motif [DE]xxxHxxD. The third conserved region contains a hydrophobic patch and a well-conserved Arg residue. Most examples are found in the Actinobacteria, including the genera Mycobacterium, Corynebacterium, Streptomyces, Nocardia, Frankia, etc. The pattern of near-invariant residues against a backdrop of extreme sequence divergence suggests enzymatic activity and conservation of active site residues.	2.85268e-26
CP029361.1\|AWL87450.1\|3782039_3782996_+\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	1.23248e-66
CP029361.1\|AWL87442.1\|3771945_3773253_+\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	5.8333e-33
CP029361.1\|AWL87455.1\|3789498_3791112_-\|methionine--tRNA-ligase	gnl\|CDD\|237012	PRK11893, PRK11893, methionyl-tRNA synthetase; Reviewed.	0
CP029361.1\|AWL87460.1\|3797244_3797646_+\|RNA-binding-protein	gnl\|CDD\|224109	COG1188, COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) [Translation, ribosomal structure and biogenesis].	4.67997e-22
CP029361.1\|AWL87445.1\|3775200_3775692_-\|hypothetical-protein	gnl\|CDD\|227231	COG4894, COG4894, Uncharacterized conserved protein [Function unknown].	1.57308e-31
CP029361.1\|AWL87458.1\|3793149_3794739_-\|hypothetical-protein	gnl\|CDD\|378410	pfam10138, vWA-TerF-like, vWA found in TerF C-terminus. vWA domain fused to TerD domain typified by the TerF protein. Some times found as solos.	3.53725e-59
CP029361.1\|AWL87459.1\|3795033_3797103_+\|PhoX-family-protein	gnl\|CDD\|253386	pfam05787, DUF839, Bacterial protein of unknown function (DUF839). This family consists of several bacterial proteins of unknown function that contain a predicted beta-propeller repeats.	0
CP029361.1\|AWL87447.1\|3777621_3777843_-\|hypothetical-protein	gnl\|CDD\|376437	pfam01027, Bax1-I, Inhibitor of apoptosis-promoting Bax1. Programmed cell-death involves a set of Bcl-2 family proteins, some of which inhibit apoptosis (Bcl-2 and Bcl-XL) and some of which promote it (Bax and Bak). Human Bax inhibitor, BI-1, is an evolutionarily conserved integral membrane protein containing multiple membrane-spanning segments predominantly localized to intracellular membranes. It has 6-7 membrane-spanning domains. The C termini of the mammalian BI-1 proteins are comprised of basic amino acids resembling some nuclear targeting sequences, but otherwise the predicted proteins lack motifs that suggest a function. As plant BI-1 appears to localize predominantly to the ER, we hypothesized that plant BI-1 could also regulate cell death triggered by ER stress. BI-1 appears to exert its effect through an interaction with calmodulin. The budding yeast member of this family has been found unexpectedly to encode a BH3 domain-containing protein (Ybh3p) that regulates the mitochondrial pathway of apoptosis in a phylogenetically conserved manner. Examination of the crystal structure of a bacterial member of this family shows that these proteins mediate a calcium leak across the membrane that is pH-dependent. Calcium homoeostasis balances passive calcium leak with active calcium uptake. The structure exists in a pore-closed and pore-open conformation, at pHs of 8 and 6 respectively, and the pore can be opened by intracrystalline transition; together these findings suggest that pH controls the conformational transition.	0.00689367
CP029361.1\|AWL87448.1\|3779398_3781225_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173842	cd01153, ACAD_fadE5, Putative acyl-CoA dehydrogenases similar to fadE5. Putative acyl-CoA dehydrogenase (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	0
CP029361.1\|AWL90461.1\|3777946_3779245_-\|M18-family-aminopeptidase	gnl\|CDD\|235073	PRK02813, PRK02813, putative aminopeptidase 2; Provisional.	0
CP029361.1\|AWL87449.1\|3781393_3781861_+\|SseB-family-protein	gnl\|CDD\|377787	pfam07179, SseB, SseB protein N-terminal domain. This family consists of several SseB proteins which appear to be found exclusively in Enterobacteria. SseB is known to enhance serine-sensitivity in Escherichia coli and is part of the Salmonella pathogenicity island 2 (SPI-2) translocon. This entry contains the presumed N-terminal domain of SseB.	0.0014028
CP029361.1\|AWL87444.1\|3774325_3775117_+\|carbon-nitrogen-family-hydrolase	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	7.55695e-116
CP029361.1\|AWL87457.1\|3791944_3793216_+\|sensor-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.43214e-42

>CP029361.1|AWL87450.1|3782039_3782996_+|pirin-family-protein
MPAVTVDNPLTLPKVAASGDAVARPVLAVTTAPSGFEGEGFPVRRAFAGINYRHLDPFIMMDQMGEVEYAAGEPKGTPWHPHRGFETVTYLIDGTFIHQDSNGGGGTIENGDTQWMTAGSGLLHIEAPPESLVQSGGLFHGLQLWVNLPKADKMMDPRYQDIRGGEVQLLASPDGGALLRVIAGELDGHQGPGITHTPITMIHATVRPGAEVTLPWREDFNGLAYVLAGRGTVGAERRPIAMGQTAVFGAGGSLTVRADERQDGHTPDLEVVLLGGRPIREPMAHYGPFVMNSQAELKQAFEDFQAGRLGTVPAVHGM
>CP029361.1|AWL87449.1|3781393_3781861_+|SseB-family-protein
MYGYDQNPGAQQQMGQMGQMGRMGGGYGEQPLYPEPSPPSLADAVRAFTTGSLSAEDFQQIFATSKVYCPRGDNPGFLALHNTQQPVIPMFTTLKELRRYAGKESKYFVITGAEVIDLLPTGYGFVLDMEGDHRMVFDAKAVEQMVDFAMRRMYG
>CP029361.1|AWL87448.1|3779398_3781225_-|acyl-CoA-dehydrogenase
MGHYKSNLRDIEFNLFEVLGRDKVYGAGPFGEMDVDTAKSILDEVARLAENELADSFADADRNPPVFDPETKTAPVPASFKKSYQAFMDSEYWRLGLPEEIGGTTSPRSLIWGYAELLLGSNPAVWMYSSGPAFAGILFDEGNEDQKKIAEIAVEKQWGSTMVLTEPDAGSDVGAGRTKAVQQEDGSWHIEGVKRFITSGEHDMSENIIHYVLARPEGAGPGTKGLSLFMVPKFHFDWTTGELGERNGVYATNVEHKMGLKASNTCEMTFGDQHPAKGWLIGDKHDGIRQMFRIIEFARMMVGTKAIATLSTGYLNALEYAKERVQGPDLANFMDKTAPKVTITHHPDVRRSLMTQKAYAEGMRSLVLYTASVQDAIQEQEAAGEDAKALNGLNDLLLPIVKGYGSEKSYEQLAQSLQTFGGSGYLQEYPVEQYIRDAKIDTLYEGTTAIQGQDFFFRKIVRDQGASLNTLSEEIKKFLAGAQGNEELAPALDSLAKAAVDLEAIVGTMITDLTATGEDVKNIYKVGLNTTRLLMASGDVVVGYLLLKGAAVATEKLPTASAKDVPFYQGKIAAAKFFAANVLPGVSTERALAESIDNSLMELDEAAF
>CP029361.1|AWL90461.1|3777946_3779245_-|M18-family-aminopeptidase
MSSPLRFDRAHTDDLMTFLAASPSPYHAVANAAARLAEAGFRQVEETAAWDGSAGGKYVLRGGAIVAWYVPEGAEAHTPFRIAGAHTDSPNLRVKPLPDTGAHGWRQIAVEVYGGTLLNTWLDRDLGLAGRISLRDGTHRLVNIDRALLRVPQLAVHLDRSANTEGLKLDRQKHMQPIWGLGDVEEGDLIRFVAEEAGVDAEDVTGWDLMPHAIEPPSYLGRDRELVAGPRMDNLLSVHAATAALAAVAGLPDADIPYIPVFAAFDHEENGSQSDTGADGPLLGSVLERSVFARGGTYEDRARAFAGTVCLSSDTGHAVHPNYAERHDPTHHPVANGGPILKVNVNMRYATDGSGRAVFAAACEKAGVPWQSFVSNNAMPCGTTIGPITAARHGIQTVDIGVAILSMHSARELCGADDPYLLANALTAFLAG
>CP029361.1|AWL87447.1|3777621_3777843_-|hypothetical-protein
MGLGGCILLIGAGAILAFATDWKMDTVNVDLVGWIMMLVGLVGVFVYMSIARRRRMVVPPTTTVVQDDQQRYQ
>CP029361.1|AWL87446.1|3775756_3777574_+|alkyl-hydroperoxide-reductase
MATRARVRAPELIGKGGWLNTGDQQYTLADLRGRIVILDFWTFCCVNCLHVLDELRELEEKHRDTVVIIGVHSPKFVHEAEHQAVVDAVERYEVHHPVLDDPELATWKQYAVRAWPTLVVIDPEGYVVAQHAGEGHAHAIEKLVEELEAEHGAKGTLRRGDGPYVAPEPVATHLRFPGKALLLPDGGFLVSDTTRHRLVELDADGETVRRHFGTGERGLSDGGPDEARFSEPQGLAVLPDGRVAVADTVNHALRALDLTTGVTSTLAGTGRQWWQGTPTSGPAREVDLSSPWDLAWFGDRLWIAMAGVHQLWTYDPGSATVRVAAGTTNEGLVDGPAAEAWFAQPSGLAVSADGERLWVADSETSALRWVDRDEHVHTAVGTGLFDFGHRDGAADQALLQHPIGVTALPDGSVAISDTYNHALRRYDPASGEVTTLATDVREPSDAVLVDGDLVVVESARHRLTRLRLPEEAVRVADQAHRTQRAATEIAPGTLRLDVVFQAPAGQKLDTRYGPSTRLLVSATPPELLADGSGAGTDLGRDLVLADGVTEGVLHVSAMAASCDDDPANEYPACHVHQQDWGVPVRVTAAGASRLALVLAGMDEQG
>CP029361.1|AWL87445.1|3775200_3775692_-|hypothetical-protein
MRLLVRERLFAIGDDYWIEDDGGRKVFLVDGKAMRLRDTFELKDTDGRVLVELRQKLISLRDTMLIERGGEELAKVKRKRLSLLRNHYRVTLVDGTELDVSGKILDREFAIEYDGELLAQISRRWLTLRDTYGIDVVRDDADTALLIAVAMCVIVLADKESEG
>CP029361.1|AWL87444.1|3774325_3775117_+|carbon-nitrogen-family-hydrolase
MRASLIQIAVDPDESVEARRVRAASLVVAQRGADLVVLPELWPVGAFAYTAFEAEAEPLEGPTHEAMAKAAAEAGVWLHAGSFVERADDGTLYNTSLVFSPEGERTAAYRKIHRFGFDQGEAVMMGAGEELVTVALPDTTLGLATCYDLRFPEQFRGLVDAGAETLVVAAGWPERRRSHWTLLAQARAVENQAYVLAVGTAGTHGDIQQAGHSIVVDPWGEVLAQAGADEEVLTVELDADKVRATREQFPALKDRRLGLTSPL
>CP029361.1|AWL87443.1|3773299_3774124_-|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MTVHPSLQPYTDAATHSIEAIAELVKPLPESEWNRRTPCPGWSVRDIVSHVIGMECEMLGDPRPIHTLPRDLYHVQSDFARYMEMQVDVRRHHTSPEITAELEYVLIRRARQIRNESRSPETKVRAPLGAEQTLETALNLRAFDVWVHEQDLRTTLGQPGNLDSPGALITRDMLLLGLPKVVAKGAGAPANSAVVFDVHGPVEFLRTVRVDAEGRGSIDGAPSLGPAVTLSLDWETYVRLACGRVRHAAVADRIKVEGDQELATAILDNFTVTP
>CP029361.1|AWL87442.1|3771945_3773253_+|MFS-transporter
MSSAAPTLSLPGDPPGGRRAAWVWGVGVAVYFVAIIFRTSLGVAGLDAADRFDVNASALSTFSILQLLVYAGMQIPVGLMVDRLGTKKVLTIGVVLFTVGQLGFALSPSYGMALAARALLGCGDAMTFISVLRLGSRWFPARRGPLIGQVAALFGMAGNLVSTLFIARALHSYGWTTTFVGSSLAGVVVLVLLLLFLKDHPEGHEPPPAEHAGAAYVRRQIAAAWREPGTRLGMWVHFTTQFPAMVFLLLWGMPFLVEAQELSRGTAGALLTLVVLSNMVVGLVYGQIIARHHEARTPIALGTVATTALLWASAIFYPADHTPMWLLVVLCLVLGACGPASMVGFDFARPANPPERQGTASGIVNMGGFVASMTTLLAVGFLLDATGDNYRVAFASVFVLEAFGVAQILRLRRRAALREREHHVVSRVEAVHVPA
>CP029361.1|AWL87452.1|3784306_3786424_-|phosphatase
MRTEEVLAAIATGLWRWDNAAGTVTLDAEAARLLGLPPEPSSYREAAVRSRFHPVDWNEIYGVVNLAVAEGSLAEARLRIVDERGQVLRTVRSRSKPVFRTDEDADSEAYVLYGTLQEVAEPQPGATDAAHTPITGDWRRSREAFLLDAGRALAEARSTAEVLRVAGSLSMPGFSPDGLAVFGSAGERLTIIGHHGHNIGDEEPFTDMPLDTDYPAAEVVRTGRAIYLPSPDEYRRRYPATWPLARRFGRQSWAFLPLVSSGRTMGAWMAGFQHPVGFSPDERAVLSTVARMLAQALARAGVAETERELSLGLQRSMMPTLGPEIPGMTVAARYVPTGGGLQVGGDWYDMIPLPNGRIALVIGDVQGHDVRAAGLMGQLRIALRAYASEGHRPDAVLARASRFLSGLTDAYESVEGDKEPAAPRFATCLYAEVDPEAGTLDIARAGHPDPVVISADGTAVIRQTAGGLPLGIETDSDYPTTRVVLEPGETIMLCTDGLIETGGHDMATGWTRLRPVLEKPVEDLEQLADALVQAVHGPTSHYTTGPLADRREDDIAVLVLRRESAPAPETAARRSVLTIAQAEPERISVGRQLVRELLHDWSDPEQVDSAVLMVSEMATNVLVHTDGDALMVAEVSGEQGERRLRVEVADASDELPHKRRPGEMASSGRGLVLMEMLADAWGVDPRGEGKSIWFELYESDEPGVF
>CP029361.1|AWL87453.1|3786589_3788383_+|aspartate--tRNA-ligase
MHRYRSHTCGELRASDVGTDVRLSGWLHNRRDLGGILFIDLRDHYGLVQLVARPGTPGNEALAKLTKETVVRIDGKVSARGADNVNPELPTGEIEIEVSEVEVLGEAAPLPFTINTEDGVNEERRLEYRFLDLRRERMHRNIMLRSAVIASIRSKMVALGFNEMATPILTATSPEGARDFVVPSRLNPGKFYALPQAPQQFKQLLMISGFDRYFQIAPCFRDEDARADRSPGEFYQLDVEMSFVEQEDVFQPIEKLMTELFTEFGNGREVTSPFPRIPFRESMLKYGNDKPDLRAKLELVDISDVFADSGFKAFAGKHVRALPVPDTAGQSRKFFDGLGEYAVEHGAKGLAWVRVGEDGTLAGPIAKFLTETDVKTLTERLSLVPGHAVFFGAGEFDEVSKIMSAVRVEAAKRAGHFEEGVFRFCWIVDFPMYERDEETGKIDFSHNPFSMPQGGLADLEEKDPLDILAWQYDIVCNGIELSSGAIRNHEPELMLKAFEIAGYDRETVEHEFAGMLRAFRLGAPPHGGIAPGVDRIVMLLADEPNIRETIAFPLNGNAQDLMMGAPTELDETRLRELNIQLRKPVAAKGASEKPADQ
>CP029361.1|AWL87454.1|3788620_3789412_+|hypothetical-protein
MSLPRRPPALLTAPLLALALLLTGCSSGAAPEKAPVGVPGQGAAGPQSDAASALRSSPSPVPAPSPAEIPDLGPETLAQIPDEARQAFVVTGEEADSYRSSAVLYSRADPAQGWEPVAGPWPAHNGMEGWTDHHVAGDRRSPTGVYTLTDAGGRLPDPGALLPYDEHPRFAVDGEGFFGEPLEGSFDYVVAINYNRTEGVSPLNRTRPLGLERGGGIWIHVDHDGPTQGCVSVPEERMEELLRTLDPAMNPVIVMGDAESLAR
>CP029361.1|AWL87455.1|3789498_3791112_-|methionine--tRNA-ligase
MAATGSEKQGATAYYVSTPIYYVNDAPHLGHAYTTVAGDVLTRWHRQRGEKVWYLTGTDEHGQKIMRTAEANDVTPQAWADKLVEEAWKPLWEHLNIANDDFIRTTEKRHTDRVQEFVQDLYDKGEIYKGGYEGPYCVGCEEYKLPGDLIDGEGEFAGQKLCPIHKKPVELLKEENYFFKLSEYGPKLLEFYAANPDFIQPESARNEVVNFVEQGLQDLSISRSTFDWGVPVPWDDKHVIYVWVDALLNYATAVGYGANQEKFDSTFPANVHLIGKDILRFHSVIWPAMLMAQGLPLPGKVVANGWLMVGGEKMSKSNLTGIKPQDLTSHFGVDAYRWYFLRAISYGSDGSFSWEDFSARYTSELANDYGNLASRVAAMVGKYFGGALPEETAAGDAEQAVRDGLAKAVATADRKIGEELDFQGGILAIFDFVKQVNGYITEQEPWKVAKDTTPEGQARLATILYTAAESLRGVAVLLNSVMPETSQKLWESLGAEESLGALADQKVQDAGAWGILPAGATVTKGAVLFPRLEEKPA
>CP029361.1|AWL87456.1|3791270_3791948_+|DNA-binding-response-regulator
MHEAGDITMRVLVAEDEEILAELVATGLRRAGFAVDTVYSGDAALAYLGLHDYDVVVLDRDLPRVHGDDVARRLVASGSRTRILMLTASGTMEDRVAGLDLGADDYVAKPFEFPELVSRVRALRRRSARPVPPQLERHGIRLDTVRRSALRDGRDLDLSPKEFTVLQLLLEADGGTVSAEELLERAWDANADPFTGAVRVCMSKLRAKLGEPALIRTVQGVGYAL
>CP029361.1|AWL87457.1|3791944_3793216_+|sensor-histidine-kinase
MKRPSPLRRLADASKLPHSTIRTRIALVYGGVFLVLGTALLATVNLASRAGTETEARAIASTAVVVVPPGYTVNGPFIARSSTGSPTAYELTDHVSDAAGKQLLNWSFAALLVMTAGAVGVGWWIAGRVLRPVHAMTAKARRLSEKTLHERIASSGPDDELKELGETLDALLGRLEKAFDSQRRFIANASHELRTPLATQRAAIQIGLDDPSPEDLVRTRQTLLDTNRRSERLIEGLLVLARSERGLATDEREVVRLDHVVREETARYPAARSEGAGGGGPEVNVSVAACSVRGNRLLLAQLVANLLANAVTYNVPGGSVQVALSKEGALLVRNTGPVVSEADVPGFFEPFRRGEGRDRMGPGSGLGLSIVRSIAVAHGGTVTAVPGPEGGGLAVTVRLPVDQAPEPASRAAVQSGSPARISR
>CP029361.1|AWL87458.1|3793149_3794739_-|hypothetical-protein
MGIRSLLRKVFGRTEQDEPTTATVPPQAERTQPKETEPETTSAAEPAAEPKASIPAPASPSSPVAGPTDRAGSPASDLVAEAFDKAAAAPASPTVPAQGSAPEDALDDAPADAPKDSPKAEKHEEPVAAEPVVVEEPVKAEAPESTPEPITIDLDLDEAAKAAPAQESTPAPAEAPESAPEVPQAAAEAPKATEAPGTSRASETPEAPEAAAAPEPAEAPLVVETLEPAETPVLAETPAPAKTPVVVETPAVVEAPPVVETPAVAETPVAPAAPEPTAPAAAEEPAPAASEPALSEPAPGKPATTLARVKSRAPQLAAPYKAAQAALKAHGLTGLRARVYLVLDRSGSMRPFYKDGSAQHLGDRTLALAAHLDEDPTVQVVFFSTDIDGTGSLELSGHEGRVDELNAGLGRLGRTHYHRAVEEVVADYEKAEATGPALVIFQTDGPPDAKQAARQALTDAARLPLFFQFVAFGEQDAKGFDFLRKLDAPNAGFFHAGPAPREIADAELYREILAGLPDWTAAREAGSGA
>CP029361.1|AWL87459.1|3795033_3797103_+|PhoX-family-protein
MRNLLPFISSHPGGRSALTCRFRCGDACFKETPNNSDNEYAGDIIAGAVSRRSMMRAAAVVTVATAAGTAALTGPSAPQAEAAALAGHGNKPGRPQKPGASGARGLRFSPVAPNKDDKVTVPDGYAQNVVIRWGEPILRGAPAFDPDKQTAKAQAGQFGYNNDFLSLLPLRGERGRQVMVANHEYTDEILMFRGYDPANPTREQVKIAWAAHGLSVVVVQEEHRTGKLGPVNRHPLNRRLTATSEFRMTGPAAGSTLLRTSADRTGRKVLGTLNNCAGGTTPWGTTLHGEENFNQYFANGTTAMHKRYGIGTSASERKWERFDRRFDLAKEPNEANRFGWVVELDPYDPDSTPRKRTALGRFKHEAAQPRLTSDGRPVVYMGDDEKFDYLYKFVSSKRMKKGNSRAAREHNLTLLDEGTLYVAKLTGDSPVNEIDGTGKLPNDGEFDGSGVWIPLATGTTSHVPGMTAEEVYVYTRLAGDKVGATKMDRPEDVEPSPRTGRVYVALTNNSDRGKEGKPGADEANPRNANKHGQILELAENWDDPTSDGFAWRLFLVAGDPDDPATYFAGFPKSSVSPISCPDNVAFDAHGNLWISTDGNALGSHDGLFGVATHGDRRGELKQFLTVPTGAETCGPVIQDRRVLVAVQHPGEIDGASVEKPASVWPDGPGKIVRPSVVAVWRKDGRDIGV
>CP029361.1|AWL87460.1|3797244_3797646_+|RNA-binding-protein
MVSGDAPQAEGSVRVDVWIWSVRLTKTRAQAAAACRAGHVKVGGDRAKPAQAVRVGDEVRLRHAGRDRVVVVSKIVKKRVGPPVAVECFVDNSPPPPPREIAIQVPVRDRGAGRPTKRDRREMERLQGRSPES
>CP029361.1|AWL87461.1|3797691_3797937_-|DUF2630-domain-containing-protein
MADSDIFENIDELVSEERDLRDRSVAKMGLSTDEKARLRAVEVQLDQCWDLLRRRRALSEYGEDPSTAKVRPADEVEGYQS

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Crispr_ID: CP029361_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029361_7

4235758-4235820

Orphan

Consensus_repeat	Method
CGGACTGCTGATGCGGACTGCTGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029361_7

>merge|CP029361|7|4235758-4235820|CRISPRCasFinder
CGGACTGCTGATGCGGACTGCTGACGCGGAACGCTGCTGCGTGCTGCTGATGCGGACTGCTGA

>CP029361|7|6|4235758-4235820|CRISPRCasFinder
CGGACTGCTGATGCGGACTGCTGA	CGCGGAACGCTGCTG
CGTGCTGCTGATGCGGACTGCTGA

Protein	Signature genes	Signature genes Name	Protein_function
CP029361.1\|AWL87796.1\|4237440_4238262_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378964
CP029361.1\|AWL87800.1\|4242979_4244236_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|200598
CP029361.1\|AWL87785.1\|4225920_4227114_+\|RtcB-family-protein	unknown	unknown	gnl\|CDD\|376465
CP029361.1\|AWL87786.1\|4227162_4227837_-\|hypothetical-protein	unknown	unknown	unknown
CP029361.1\|AWL87795.1\|4236618_4237353_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376668
CP029361.1\|AWL87787.1\|4228010_4228661_-\|HAD-family-phosphatase	unknown	unknown	gnl\|CDD\|223710
CP029361.1\|AWL87791.1\|4232818_4233892_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
CP029361.1\|AWL87790.1\|4231943_4232822_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224098
CP029361.1\|AWL90500.1\|4238358_4238955_+\|TIGR03086-family-protein	unknown	unknown	gnl\|CDD\|274424
CP029361.1\|AWL87798.1\|4239391_4239976_-\|hypothetical-protein	unknown	unknown	unknown
CP029361.1\|AWL87799.1\|4241576_4242305_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366010
CP029361.1\|AWL87797.1\|4238869_4239211_-\|hypothetical-protein	unknown	unknown	unknown
CP029361.1\|AWL90501.1\|4240308_4241580_+\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|234607
CP029361.1\|AWL87793.1\|4234984_4235743_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|226674
CP029361.1\|AWL87792.1\|4233911_4234910_+\|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl\|CDD\|377028
CP029361.1\|AWL87794.1\|4235898_4236606_+\|ABC-transporter	unknown	unknown	gnl\|CDD\|226425
CP029361.1\|AWL87789.1\|4229845_4230994_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270267
CP029361.1\|AWL87801.1\|4244303_4244906_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
CP029361.1\|AWL90499.1\|4231065_4231956_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226616
CP029361.1\|AWL87788.1\|4228777_4229518_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099

Protein	Function_ID	Function_description	E-value
CP029361.1\|AWL87796.1\|4237440_4238262_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|378964	pfam12833, HTH_18, Helix-turn-helix domain.	7.32152e-16
CP029361.1\|AWL87800.1\|4242979_4244236_+\|hypothetical-protein	gnl\|CDD\|200598	cd10976, CE4_CDA_like_3, Putative catalytic domain of uncharacterized bacterial hypothetical proteins similar to insect chitin deacetylase-like proteins. The family includes many uncharacterized bacterial hypothetical proteins that show high sequence similarity to insect chitin deacetylase-like proteins. Chitin deacetylases (CDAs, EC 3.5.1.41) are secreted metalloproteins belonging to a family of extracellular chitin-modifying enzymes that catalyze the N-deacetylation of chitin, a beta-1,4-linked N-acetylglucosamine polymer, to form chitosan, a polymer of beta-(1,4)-linked d-glucosamine residues.	5.39403e-122
CP029361.1\|AWL87785.1\|4225920_4227114_+\|RtcB-family-protein	gnl\|CDD\|376465	pfam01139, RtcB, tRNA-splicing ligase RtcB. This family of RNA ligases (EC:6.5.1.3) join 2',3'-cyclic phosphate and 5'-OH ends. They catalyze the splicing of tRNA and may also participate in tRNA repair and recovery from stress-induced RNA damage.	2.16566e-176
CP029361.1\|AWL87795.1\|4236618_4237353_-\|hypothetical-protein	gnl\|CDD\|376668	pfam01927, Mut7-C, Mut7-C RNAse domain. RNAse domain of the PIN fold with an inserted Zinc Ribbon at the C-terminus.	3.9305e-57
CP029361.1\|AWL87787.1\|4228010_4228661_-\|HAD-family-phosphatase	gnl\|CDD\|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	2.07992e-38
CP029361.1\|AWL87791.1\|4232818_4233892_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	5.42981e-154
CP029361.1\|AWL87790.1\|4231943_4232822_+\|ABC-transporter-permease	gnl\|CDD\|224098	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism].	5.60022e-33
CP029361.1\|AWL90500.1\|4238358_4238955_+\|TIGR03086-family-protein	gnl\|CDD\|274424	TIGR03086, TIGR03086, TIGR03086 family protein. This family, like pfam07398 and TIGRFAMs family TIGR030834, belongs to the larger set of probable enzymes defined in family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized.	4.44116e-29
CP029361.1\|AWL87799.1\|4241576_4242305_+\|histidine-phosphatase-family-protein	gnl\|CDD\|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	1.76558e-40
CP029361.1\|AWL90501.1\|4240308_4241580_+\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|234607	PRK00062, PRK00062, glutamate-1-semialdehyde 2,1-aminomutase.	0
CP029361.1\|AWL87793.1\|4234984_4235743_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|226674	COG4221, COG4221, Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only].	2.83345e-85
CP029361.1\|AWL87792.1\|4233911_4234910_+\|endonuclease/exonuclease/phosphatase-family-protein	gnl\|CDD\|377028	pfam03372, Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. This family includes: AP endonuclease proteins EC:4.2.99.18, DNase I proteins EC:3.1.21.1, Synaptojanin an inositol-1,4,5-trisphosphate phosphatase EC:3.1.3.56, Sphingomyelinase EC:3.1.4.12, and Nocturnin.	1.41387e-11
CP029361.1\|AWL87794.1\|4235898_4236606_+\|ABC-transporter	gnl\|CDD\|226425	COG3910, COG3910, Predicted ATPase [General function prediction only].	1.04352e-60
CP029361.1\|AWL87789.1\|4229845_4230994_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270267	cd13549, PBP2_Fbp_like_3, Substrate binding domain of an uncharacterized ferric iron transporter, a member of the type 2 periplasmic binding fold superfamily. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. This periplasmic domain (Fbp) has high affinity for ferric iron and serves as the primary receptor for transport. After binding iron with high affinity, Fbp interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ferric iron-binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.67775e-51
CP029361.1\|AWL87801.1\|4244303_4244906_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	5.35769e-43
CP029361.1\|AWL90499.1\|4231065_4231956_+\|ABC-transporter-permease	gnl\|CDD\|226616	COG4132, COG4132, ABC-type uncharacterized transport system, permease component [General function prediction only].	5.36213e-62
CP029361.1\|AWL87788.1\|4228777_4229518_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.02202e-53

>CP029361.1|AWL87793.1|4234984_4235743_-|SDR-family-NAD(P)-dependent-oxidoreductase
MAATPIAVVTGASSGIGAATARTLAAEGFRVVLTARRTDRIEALAAELNEAGHQATAYALDVTDRAAVDEFATAFRSLAVLVNNAGGALGADPVATGDPADWRQMYETNVIGTLNVTQALLPALTASGDGTIVILSSTAALSSYEGGGGYVAAKHGEHVLAETLRLEIVGTPVRVIEVAPGMVRTEEFATTRFRGDTEKAAKVYAGVDAPLTAEDVADTIGWAVTRPSHVNIDLLVVRPRAQASNTKVHRTL
>CP029361.1|AWL87792.1|4233911_4234910_+|endonuclease/exonuclease/phosphatase-family-protein
MSAKRRVFLSATGAAVALAATAAVAVAGPVAKSDGPPESPKPGKPAAASELRVMTLNLWHGGAKVDDGLAKQLAVIEKHRPDVVGLQETSGHSAKEIAEELGWDHWQSDADLGIISRFPFTSEVETSQAAAGVRIRIDEATGQEVELWTAHLGYDPYGPYDACFDGMAVEDIFQREAQSGRTPQAEAIAKDLAPKIAAADETPVLLVGDFNTPSHLDWTEATKDSHCGYGQVDWPVTKIFEGAGLKDSFREANPDPAAVPGNTWSPVYPKHEGSTGVAEPQDRIDFIDYAGDKLTVKDSVSFVEGDPKPVPDQAGNVWPTDHAAVLTTFTVG
>CP029361.1|AWL87791.1|4232818_4233892_+|ABC-transporter-ATP-binding-protein
MTVSVHLKNLRREFGSTVALDGLDLDIAPGELVALLGPSGCGKTTALRIVAGFETADGGELLMDGEDVTSVPANRRDIGMVFQSYSLFPNMTAAENIAYGLRVRGRGAAERKARAGELLELVGLPGREGDYPHQLSGGQQQRVALARALAISPKVLLLDEPLSALDAKVRLTLREEIRRIQLELGITTVFVTHDQEEALSMADRVAVMKDGRLEQCAAPGELYDRPATPFVAEFVGTMNRLPGTVRDGGVVELFGRRLPIHGDRPAPGAEVDVLLRPEGLAVGAADDGTGAPATVRVATFLGATTRLHLTTDSGAACKADLPSWEATALAPGTRCTITPHENPVLVAERAGAPSLKV
>CP029361.1|AWL87790.1|4231943_4232822_+|ABC-transporter-permease
MARMKFTSRAVVLPLAALYFLVPIGASIWFSVNEVEGVSFDAYTQGLGTEGLTTSLMLSVRLGLATIVCGLLLMVPTLVAVALYLPGLRRTVEVLCMMPLVVPPIALVAGVTTVLSWEQDLADTPFYMTFQMLRDESFPLVLVLVYTVMSLPFLYRSLDAGLRAVDLRTLVEAARSLGASRLQTLWQVIVPNLRTAVVGGAVLSLAMVLGEYTVASVLSYRPFSVWMVEIKDSEAQLSVAAAMLSLLITWGLLLLLTTLAGGRGRRRRTPVDSGREDREDRESRDDRKKTVS
>CP029361.1|AWL90499.1|4231065_4231956_+|ABC-transporter-permease
MPPAPDVRGGGAPRRRGARRHRWPVVVPFFAFLAVCFGLPAGTMVYGAFTVLDPESGASRFSTENVSGSLSGAYATGLTGSVELSLFTALLATVIGTLIAQAVVTSPRPVLRGIVVSASGVLANFSGAPLAFAFIATLGTTGTVTQLFHLDRTGFSLYSFTGLVLAYLYFMVPLMVVTVLPALDGLRSQWQEAAASCGATRGQYWRHVGIPVLTPSLLGGAVLMFGTAFASHATAAVMVGSSQPLITIQIANALNGNVLVGQENLALAMSLNMVVIALLVMAVQIPLQRRSARWLG
>CP029361.1|AWL87789.1|4229845_4230994_+|ABC-transporter-substrate-binding-protein
MKAHHPRRVLTAAALAGLTALVATGCGSAPDNAGGQNSKAAKAESAADLGGMEKLVAAAEKEGKLNVYALAPDWANYGEMIAAFEKKYAIEVNNEDPGGSSQGALNAAAKRKGQARAVDALDLGTSYMQDAKKQGLLAPYRVAGWDAIPDAQKQPDASFMNNYGGYISIGCDAKAVKNCPETFKDLLKPEYRNKVALNGDPTESSSALAAVVAASLASGGSLDDAQPGLDFFQQLKKKGNFVPAKSTLATIQQGETPISIDWDYLNLGYGEKLKPKGVDWQVAVPADGLYSRYYNQGVNKHAPHPAAARLWLEFVYSPEGQNIWLKGFSRPALLDAMKKDGTADKAAVAAIPEVDGVPEEPTVEQEAKAKETVVQGWGKAVS
>CP029361.1|AWL87788.1|4228777_4229518_-|GntR-family-transcriptional-regulator
MTRRHQQIAEELRRAIADGTHPVGSELPSESELALVHGVSRGTLRQAFGTLQSEGLIGSRQGARRTVLSTTPSQSFTELRSFAQWARAGDRAPGGLVLRSHRARATEAQASQLQLVPGEMVLNVLRLRTLDGEAALLERTVYAGWAAAAVEALPDDCESVTQSLYETAGVVMSHGEHHLDAVAAGTTDARELGVRRGSPLLRVRRTTTTSEGRPVETSDDRYRPGSVVFTVRNSVQANPLVRTAAD
>CP029361.1|AWL87787.1|4228010_4228661_-|HAD-family-phosphatase
MPPLPRPAALLCDMDGTLVDTEHAWLDTVAGFLRTQGSPAGATTLAPFAGAALADAADRLVRDGLTALSPEETLARLDQEFTARVAAGVAVQPGALRLLDRARALGVPTALVTASERHVADLVLDTLGRHRFDTSVASGETTRGKPHPDPYLAAAAALGVAPQDCLAVEDTPTGASAALAAGCRLLAVPSVPGIEPGPRTVLVASLTEADLVDAVG
>CP029361.1|AWL87786.1|4227162_4227837_-|hypothetical-protein
MAEHDTNAPPLFELGDVSPAPPTAPAIWTLCDREARATVNGLGLPYGRKSRKITPPRVEFSRRDYLRGVIDADGSVGHTGQGLPFVSLTTASAPVGAYLCRYAKAVTGSARQIGRNARDGIYNVVYTKEAAVRLAGHLYYPGCLSLARKQTSATALASWERPADMPVRSPGRRWKPWEDRALLAHDDAASAAAELGRSAASCSVRLWRLKTGKVRRPEDGPADT
>CP029361.1|AWL87785.1|4225920_4227114_+|RtcB-family-protein
MSYVEVPGAKVPIRMWTDPASVEDVAMQQLRNVSTLPWIKGLAVMPDVHFGKGATVGSVIAMQGAVCPAAVGVDIGCGMSAVKTSLTANDLPGDLSRLRSKIEQAIPVGRGMHGDAVDPGRLHGFPTAGWDDFWGRFGGIAEAVKFRQERATKQMGTLGSGNHMIEFCLDSGGAVWLMLHSGSRNIGKELAEHHIGIAQKLPHNQGLVDRDLAVFVSDTPQMADYRNDLYWAQEYAKYNRAIMMALFKDVVRREFKKAKPVFDQEISCHHNYVAEERYDGADLLVTRKGAIRAGSGEYGIIPGSMGTSSYIVKGLGNEKAFNSASHGAGRRMSRNAAKRRFTVRDLEEQTRGVECRKDSGVLDEIPAAYKPIDQVMEQQRDLVEVVAKLKQVICIKG
>CP029361.1|AWL87794.1|4235898_4236606_+|ABC-transporter
MIVERAYAHVYDPDPDAWPWTVPGVRQFLAEGLRFRAPVTFLVGENGSGKSTLVEAMAEGFGLDSYGGSADWKYATSRGKSVLGERVRFDSAPRGRRMIGSRAARKGFFLRAETALDALERESLDPDSRSHGEGFLAAFREKFTVPGLYVLDEPEAALSFASCLELLGHLDQLVKAGGQVVCATHSPLLTALPGADIVQLGEGGMERVRWADLELVDHWRRYLADPQAYLRHILG
>CP029361.1|AWL87795.1|4236618_4237353_-|hypothetical-protein
MNGPEITLEVAPELRLFVPHDRRGGPTPLVTDGSSTLGHVIESLGVPLTEAGTLLVNGAPVARSHVPGPGEHVDVRAVERPQRVPGAPLRFLLDVHLGTLARRLRLLGVDAAYESEDIGDPALAALSARERRVLLSRDRGLLRRREIWAGAYVYSDRPKEQLRDVLGRFAPALDPWSRCTACNGTLAGAAKDSVSGLLEHGTQEAYDVFAQCTECSRVYWRGAHHGHLETIVSEAVREFGGTPA
>CP029361.1|AWL87796.1|4237440_4238262_-|AraC-family-transcriptional-regulator
MAAGPRRDTRGIVDAPDLFAHVRFRRREPAAALRPYLEHYWLIDWDLAEPYAAHVVPHPSVNLVCQRYEAGDSPRERSGYAEVAGVDPGLFTRKLAGRGRVCGVQFRPGGFRPFAPGHPVSAWTGLHADAAEVLRLPPPLDAVLGPDDEDARVAALDAFLLALQPRPDPRAALAMAAVDRVRTDRTVRRVDGLARDTGLSARSLQRLFSAYVGVGPKWVILRYRIHEALEAAESGPEVDWARLAADLGYSDQAHLVRDFTATVGVPPTAFAPH
>CP029361.1|AWL90500.1|4238358_4238955_+|TIGR03086-family-protein
MTQTIGELLETAADRALPVVRGIDDGQLGGPTPCAEYDVRALLNHLFLVVVNFQALAAREDVDFTQEPDFVADGDWRGRFGDETARLVEAWSVPGVEEGTTGQMGLPARTVGLMVLGDLTVHAWDLARATGTDFVPERSVLDEVGPGLAAMAPQAREMKVFGEPFPVPGSSTAFERLLAVTGRDPGWTPGGTAGATGS
>CP029361.1|AWL87797.1|4238869_4239211_-|hypothetical-protein
MGDVLLALSIPVLVFGGGIYAACDCWWRRRHPAPPSPYTHRAARLAEQDMLLLAEEIVDGAYAAFGPFYDAPEPGPAEPPTEPAALSSRSPRPSRPASTPDRAPSPPAAVQKP
>CP029361.1|AWL87798.1|4239391_4239976_-|hypothetical-protein
MHRGGGVGEGTDDLGPEPARRGRHRRRAERAQSRGAESTPPPGTRSGGGMGVTYKYFGAPDGATAARVPISMRPEELGGDELGMGGMFTKIKPETVAAMVLTGIQGIPLHKVPPLELVVLHPDYAVVKLPMTVVDPLRGVGEESVGAAAFIWSTVPDRGGPRDAFNVYQLLHEWQDFSHRLHDAGHQAYCLVWP
>CP029361.1|AWL90501.1|4240308_4241580_+|glutamate-1-semialdehyde-2,1-aminomutase
MFDRASVVTPGGVNSPVRAFRAVGGTPRFMVSGTGPYLTDADGREYVDLVCSWGPMILGHSHPEVIAAVQDAVSRGTSFGTPGEGEVALAEEIVARIEPVEQVRLVSSGTEATMSAIRLARGFTGRAKVVKFAGCYHGHVDALLAAAGSGVATFGLPDTPGVTGATAGDTVVLPYNDLDAVRAAFAAHPGEIACVITEASPGNMGVVPPADGFNAGLKELCAANGALYISDEVMTGFRTSKAGWYGVDGVRPDLMTFGKVMGGGFPAAAFGGRGDVMAHLAPAGPVYQAGTLSGNPVATAAGLAQLRLLDDAAYAKIDAVSAELRSLVGDALTKEGVAHTVSAASNMFSVFFTDRPVRDYEDAKKQDAFRFTAFFHSMLEQGVYLPPSAFESWFVSTAHDERAVERIAAALPAAARAASEATA
>CP029361.1|AWL87799.1|4241576_4242305_+|histidine-phosphatase-family-protein
MSEKSTGSEGVDRDEQLTVVHVVRHGEVHNPDGVLYGRRPGYHLSDLGRKMADRVAEHLEKRDITHVVASPLERAQETADPIAQAHGLDLATDARLIEAANVFEGKTFGVGDGALRKPDNWKHLTNPFKPSWGEPYIEQVVRMMGAIDSARDAARGHEAVCVSHQLPIWILRSFVERRRLWHDPRKRQCTLASLTSFTYRGDTIVSVGYSEPARDLVPVHLLAGAKPVKGKAAKGQSKAFGA
>CP029361.1|AWL87800.1|4242979_4244236_+|hypothetical-protein
MRDINRRGLLGAGLGAAAAIGLAGCGTSGSSGDGGPGRGGKGDSGTGGNGRGNGSPKNKVRLIGDGSTADTGKQPHQPEAPVPLEPGQKPPQFVIFSWDGAGEVGNGLFPRFLELAKEHDAAMTFFLSGIYLLPESKKSLYRPPNNPRGASDIGYLTDDHVKDTLKYVRQAWLDGHEIGTHFNGHFCGGSGSVERWTPAQWHSEINQAVSFVTEWRTNTGWENEEPLPFDYRKELVGGRTPCLLGQDNLLPTASKLGWRYDASSPGGRQTWPVKRGGVWDLPLQAMPFPGHSFEVLSMDYNILANQSQNSTKGMPSRYPGWRQQATDAYLAGFQRAYESNRAPFYIGNHFEEWNGGIYMDAVEEVIKKVADKDDVRLVSFRQYVDWLDAQDPAVLAKLRTLDVGQAPAGGWNSFFKQA
>CP029361.1|AWL87801.1|4244303_4244906_+|TlpA-family-protein-disulfide-reductase
MSFGRASRRRFTLLAATAVAGALTLSACGDGNKAGGGGNTNFITGSGGVATVAKADRAAAPKLDGTSLEGKPLDLADYKGKVVVLNVWGSWCGPCRLEAKYFAQVSEETKAQGVQFVGINTRDPERDKAVNFEKDYGVKYPSFYDPIGKLILRFPKGTLNPQAIPSTVVIDRDGKIAARTLQALNGDELREMIDPIIAEK

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Crispr_ID: CP029361_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029361_8

4638229-4638324

Orphan

Consensus_repeat	Method
AGCGGGGTCCGGGGCGGAGCCCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029361_8

>merge|CP029361|8|4638229-4638324|CRISPRCasFinder
AGCGGGGTCCGGGGCGGAGCCCCGAAATCCAGCGGGTCCGGCCCCCCAGCCCGTCCGGCGCTTGAGGACAAAAGCGGGGTCCGGGGCGGGGCCCCG

>CP029361|8|7|4638229-4638324|CRISPRCasFinder
AGCGGGGTCCGGGGCGGAGCCCCG	AAATCCAGCGGGTCCGGCCCCCCAGCCCGTCCGGCGCTTGAGGACAAA
AGCGGGGTCCGGGGCGGGGCCCCG

Protein	Signature genes	Signature genes Name	Protein_function
CP029361.1\|AWL88093.1\|4629925_4633750_+\|family-2-glycosyl-transferase	unknown	unknown	gnl\|CDD\|224137
CP029361.1\|AWL88099.1\|4640363_4641539_+\|mannose-6-phosphate-isomerase,-class-I	unknown	unknown	gnl\|CDD\|185085
CP029361.1\|AWL88096.1\|4636612_4637980_+\|phosphomannomutase/phosphoglucomutase	unknown	unknown	gnl\|CDD\|236557
CP029361.1\|AWL88095.1\|4635349_4635778_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240574
CP029361.1\|AWL88105.1\|4653306_4654620_-\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
CP029361.1\|AWL88092.1\|4629356_4629620_+\|WhiB-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376791
CP029361.1\|AWL88100.1\|4641626_4642613_+\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|223131
CP029361.1\|AWL88091.1\|4628185_4628686_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380416
CP029361.1\|AWL88089.1\|4625791_4627078_-\|coenzyme-F420-0:L-glutamate-ligase	unknown	unknown	gnl\|CDD\|183957
CP029361.1\|AWL90530.1\|4636163_4636544_+\|DUF3499-domain-containing-protein	unknown	unknown	gnl\|CDD\|378788
CP029361.1\|AWL88098.1\|4639012_4640149_+\|mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|378434
CP029361.1\|AWL88103.1\|4645211_4646228_-\|RDD-family-protein	unknown	unknown	gnl\|CDD\|224628
CP029361.1\|AWL88104.1\|4646347_4647355_+\|stage-II-sporulation-protein-M	unknown	unknown	gnl\|CDD\|376676
CP029361.1\|AWL88102.1\|4644552_4645215_+\|hypothetical-protein	unknown	unknown	unknown
CP029361.1\|AWL88088.1\|4624416_4625460_+\|DNA-3-methyladenine-glycosylase-2-family-protein	unknown	unknown	gnl\|CDD\|223200
CP029361.1\|AWL88101.1\|4642890_4644348_+\|adenosylhomocysteinase	unknown	unknown	gnl\|CDD\|377487
CP029361.1\|AWL88097.1\|4638670_4638853_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225391
CP029361.1\|AWL90531.1\|4654630_4655602_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
CP029361.1\|AWL88090.1\|4627215_4628172_-\|2-phospho-L-lactate-transferase	unknown	unknown	gnl\|CDD\|237443
CP029361.1\|AWL88094.1\|4633746_4635285_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP029361.1\|AWL88093.1\|4629925_4633750_+\|family-2-glycosyl-transferase	gnl\|CDD\|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	3.99782e-33
CP029361.1\|AWL88099.1\|4640363_4641539_+\|mannose-6-phosphate-isomerase,-class-I	gnl\|CDD\|185085	PRK15131, PRK15131, mannose-6-phosphate isomerase; Provisional.	2.90072e-113
CP029361.1\|AWL88096.1\|4636612_4637980_+\|phosphomannomutase/phosphoglucomutase	gnl\|CDD\|236557	PRK09542, manB, phosphomannomutase/phosphoglucomutase; Reviewed.	0
CP029361.1\|AWL88092.1\|4629356_4629620_+\|WhiB-family-transcriptional-regulator	gnl\|CDD\|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	1.17122e-28
CP029361.1\|AWL88105.1\|4653306_4654620_-\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	3.02867e-45
CP029361.1\|AWL88095.1\|4635349_4635778_-\|hypothetical-protein	gnl\|CDD\|240574	cd12954, MMP_TTHA0227_like_1, Minimal MMP-like domain found in a group of hypothetical proteins from alphaproteobacteria and actinobacteria. The subfamily includes some uncharacterized bacterial proteins which show high sequence similarity with Thermus thermophilus hypothetical protein TTHA0227. However, they do not contain the conserved HExxH (x could be any amino acid) motif. They may not have any zinc metallo-peptidase activity.	8.92067e-26
CP029361.1\|AWL88100.1\|4641626_4642613_+\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	1.39e-39
CP029361.1\|AWL88091.1\|4628185_4628686_-\|cupin-domain-containing-protein	gnl\|CDD\|380416	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain. This family contains cysteine dioxygenase (CDO; EC 1.13.11.20), which catalyzes the conversion of cysteine to cysteine sulfinic acid, the first step in the biosynthesis of essential oxidized cysteine metabolites such as sulfate, hypotaurine, and taurine. CDO also plays an important role in the regulation of intracellular cysteine levels in mammals; CDO expression is altered in cancer cells, and abnormal or deficient CDO activity has been linked to Parkinson's disease, Alzheimer's disease, and rheumatoid arthritis. CDO is an iron-dependent thiol dioxygenase that uses molecular oxygen to oxidize the sulfhydryl group of cysteine to generate cysteine sulfinic acid. The CDO active site contains an amino acid-derived cofactor. These enzymes are found in prokaryotes as well as eukaryotes and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	7.45124e-25
CP029361.1\|AWL88089.1\|4625791_4627078_-\|coenzyme-F420-0:L-glutamate-ligase	gnl\|CDD\|183957	PRK13294, PRK13294, F420-0--gamma-glutamyl ligase; Provisional.	0
CP029361.1\|AWL90530.1\|4636163_4636544_+\|DUF3499-domain-containing-protein	gnl\|CDD\|378788	pfam12005, DUF3499, Protein of unknown function (DUF3499). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 125 to 163 amino acids in length.	1.92889e-59
CP029361.1\|AWL88098.1\|4639012_4640149_+\|mannose-6-phosphate-isomerase	gnl\|CDD\|378434	pfam10432, bact-PGI_C, Bacterial phospho-glucose isomerase C-terminal SIS domain. This is the C-terminal SIS domain of a bacterial phospho-glucose isomerase EC:5.3.1.9 protein which is similar to eukaryote homologs to the extent that the sequence includes the cluster of threonines and serines that forms the sugar phosphate-binding site in conventional PGI. This domain contributes a good proportion of the active catalytic site residues. This PGI uses the same catalytic mechanisms for both glucose ring-opening and isomerisation for the interconversion of glucose 6-phosphate to fructose 6-phosphate. It is associated with family SIS, pfam01380.	1.95881e-15
CP029361.1\|AWL88104.1\|4646347_4647355_+\|stage-II-sporulation-protein-M	gnl\|CDD\|376676	pfam01944, SpoIIM, Stage II sporulation protein M. SpoIIM is on e of four stage II sporulation proteins that is necessary for the forespore inside the mother-cell to be properly internalized through the breakdown of peptidoglycans trapped between the membranes of the septum separating the forespore and the mother-cell. The four proteins working in sequence are SpoIIB, pfam05036, SpoIIM, SpoIIP, pfam07454, and finally SpoIID, pfam08486. D, M and P are in a complex with each other and the complex assembles in a hierarchical manner such that M, which serves as a membrane anchor, recruits P to the septum and P, in turn, recruits D to the septum.	3.33927e-40
CP029361.1\|AWL88103.1\|4645211_4646228_-\|RDD-family-protein	gnl\|CDD\|224628	COG1714, COG1714, Predicted membrane protein/domain [Function unknown].	1.49141e-17
CP029361.1\|AWL88088.1\|4624416_4625460_+\|DNA-3-methyladenine-glycosylase-2-family-protein	gnl\|CDD\|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	1.91976e-28
CP029361.1\|AWL88101.1\|4642890_4644348_+\|adenosylhomocysteinase	gnl\|CDD\|377487	pfam05221, AdoHcyase, S-adenosyl-L-homocysteine hydrolase.	0
CP029361.1\|AWL88097.1\|4638670_4638853_+\|hypothetical-protein	gnl\|CDD\|225391	COG2835, COG2835, Uncharacterized conserved protein [Function unknown].	1.05558e-13
CP029361.1\|AWL90531.1\|4654630_4655602_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	2.54057e-103
CP029361.1\|AWL88090.1\|4627215_4628172_-\|2-phospho-L-lactate-transferase	gnl\|CDD\|237443	PRK13606, PRK13606, LPPG:FO 2-phospho-L-lactate transferase; Provisional.	2.67385e-174

>CP029361.1|AWL88096.1|4636612_4637980_+|phosphomannomutase/phosphoglucomutase
MVADLSQLVKAYDVRGVVPDQWDESLAELFGSAFVQVTAADAIVIGHDMRPTSPGLSRAFARGAAARGADVTLIGLCSTDQLYYASGALDLPGAMFTASHNPAQYNGIKMCRAGAAPVGQDTGLAEIRTLVEQWSEGAPRPAAATTPGTITERDTLTDYASHLLGLVDLTAIRPLKVVVDAGNGMGGHTVPTVFDGLPLDLVPMYFELDGTFPHHEANPLDPKNIVDLQARVLAEGADLGLAFDGDADRCFVVDERGAGVSPSAITALVAARELARNGGRGIVIHNLITSSSVPEVVRENGGTPVRTRVGHSFIKAEMAGHGAIFGGEHSAHYYFRDFWNADTGMLAALHVLAALGGQQKPLSELVAEYDRYTGSGEINSTVADQTASLTKVKKAYGTREDITFDDLDGLTVTAPDWWFNLRASNTEPLLRLNVEAGDEKTMTAVRDEVLGLIRG
>CP029361.1|AWL90530.1|4636163_4636544_+|DUF3499-domain-containing-protein
MVSPVRRCSRTACGRPAVATLTYVYADSTAVLGPLATYAEPHCYDLCAEHSERLTAPRGWEVVRLSDGSAPAHPSGDDLEALANAVREAARPHDRGPDGGGRGRRSADPVEVARRGHLRVLRSPDS
>CP029361.1|AWL88095.1|4635349_4635778_-|hypothetical-protein
MDSPVPPHPFEPRPRRRDRHGRGMRGPVAPPQVPLSASRGETFRDLVQDSVERLERRWPQLAEVDFVVLDVPGTPEEVVPLGSAVSAEKGRPAQIVVYRRPVEIRTKSRDERALLVHEVVVEQVAELLGLAPESVDPRYGQD
>CP029361.1|AWL88094.1|4633746_4635285_+|hypothetical-protein
MKSTHLSLIAGAAVLAAVTGFATVTAPGAPAGSTAKSAALLPVERAGLVCPAPSNSELAETQYTAFTPAGEGGEAKGAAELKPALPVVDDEDETDPKKVKKAEEAAKKAKEKAEKPVLAVKEPGKPVVAEANGSSAPALVGTATGKLAPGWTAQQTTEVTAGGSRGLLGVTCTAPDTDFWFPGASTAKSRQDYIHLTNPDDTGAVADIELYGPEGALKSDVGDGITVPARSSVAVLLSTLTSEAVDQLTAHVTTRSGRIGAVVMSADDSAGSDWITASEDPSGTLVMPGIPADATSVQLVAFAPGEDDADVKVQLMGKNATFSPAGNATLHIKSSMTASADLKDLTRGEPGSLRLSPVRKDRATPIVAALRVVRGKGDKQEIAYIPATGPVGARATVPDNRAKGSTLSLTAPGATAKVKVTASAGSGGGEPAVETYTVKAGTTLAVTPKAPEGLKGSYALTVETTSGGPVHASRSLALASDGVQMFTVQTLPDDRGMVEVPSARQDLSVLDD
>CP029361.1|AWL88093.1|4629925_4633750_+|family-2-glycosyl-transferase
MSVHSHSAAPNAAAAAPEFPRHVVTAVLVSHDGARWLPDVLAGLLGQERPVQNVVAADTGSADDSARLVTEALGDERVLHLARRTSFGTAVDEAARTAGILTPDDLPYLKRPSGWDPQTRTWVDENYDLPELPHGEPVQWLWLLHDDCAPEPDALAAMLRVVDTDKHATIVGPKLRGWYDRKQLLEVGVSIANSGRRWTGLDRREQDQGQHDQVRTVLSVSSAGMLIRRDVYEELGGFDRRLPLMRDDVDLCWRAHLAGHRVLVAPDAVLRHAEASARERRPIDCAGRSVASPHRVDKAGAVYTMLVNARGKALPWVLLRLVVGTLLRTLAYLVGKVPGQALDEITGLLGTLLRPGRILAARRNRGKGVVDAAELRALFPPPGATVRATVDQVAGNFGGRTDSDAGGSRHGVVESGPGGDDADFLEVDQFARLKRIGRKPGPILFALLLVVSLVACRNLLSGGALAGGALLPVPAELGSLWDRYADAWHTVGTGGTQTAPPYLALLAALSALFLGSTGLAVSVLLVCSIPLAGATAYFASRPLLPSRLLRAWASVAYAFLPAATGALATGRLGTAVLLVLLPLIARAGVAAHGLRADSAAGERGSWRATWAYTLLLTVTMAFTPIVWPLAVVLGLGVLVLRRGDITAYALRFVAAVATPVLVLAPWSLSLLTNPSALLTEAGLDTGTGEASGFDLLGISPGGPGAAGGILLLGIVLAALAALLREERQFAVRTAWAVALVGFLFAAVANGSTWAGPATLVYGTALIAAALVGADGARIRVAEQSFGWRQPVAALIALAAGLAPVLAAAGWMIGGADGPLERRDPVQVPAFVAEESTTRDQPRTLILGGTSPDTVSYSLVRGSGARLGDGELTEAGGSNSHLDKVVANLVAGSGADQGGQLSGFAIRYVLVRDGAPREMSRVLDATPGLSRLSQLDGSALWRVDRQVARVMITPGSGEGEHIAVGSAAVEAHSEIPSGEAGRVLRIADAADPGWTATLDGKPLPRKTVDGWAQGFELPANGGRLDLTHDAPITHTAWIWAQIGLLVVLVVMALPGRRREIDDDLPEEALAVAAEPVDGEGRRARRLRAAAQAEAAAEEAGNDDPSRAVDPGEYIPAQQTADPYAENQQAPHDPQEATGGYAAVPEQQPVPQQYDAYAQWDGQQQPTADHYATYQQQDPYAQQHQHQHHQQQGQQSAGYQRGYGVQDPYAQQYDDQGAYNGQSAAYDNQGVYDEYGRYIGGQQHQHPYTENGEQTDPPAPGQAPWQTGNASRGESE
>CP029361.1|AWL88092.1|4629356_4629620_+|WhiB-family-transcriptional-regulator
MTELFQQLLVEDADEELGWQERALCAQTDPESFFPEKGGSTREAKKVCLACEVRSECLEYALSNDERFGIWGGLSERERRRLKKAAI
>CP029361.1|AWL88091.1|4628185_4628686_-|cupin-domain-containing-protein
MNSDSDLQIAGDILEVQHLLQPAREHPSTVSEFVGLARSIAADRARWADIVRYDSASRWYHRLHQGPGYEVWLLSWVPGQGSGRHDHGLSAGVLTVLEGELTEHTERGTRSLGAGAQRSFAPGYVHEVVNDSLEPAVSLHIYYPGLTEMPMHPSQSAPTAVGAVPA
>CP029361.1|AWL88090.1|4627215_4628172_-|2-phospho-L-lactate-transferase
MRIVVLAGGIGGARFLRGLKQAAPDADITVIGNTGDDIHLFGLKVCPDLDTVMYTLGGGINEEQGWGRTDETFQVKEELAAYGVGPEWFGLGDRDFATHIVRTQMLGAGYPLSAVTEALCARWQPGVRLLPMSDDRVETHVAVEMDGENKAIHFQEYWVKLRASVEARAIVPVGAEQAKPAPGVLEAIGAADVIVFPPSNPVVSVGTILAVPGIREAIAEAGVPVVGLSPIVGDAPVRGMADKVLAAVGVESTASAVARHYGSGLLDGWLVDTVDAGAVDEVEAAGIRCRAVPLMMTDVDATAEMARQALALAEEVRA
>CP029361.1|AWL88089.1|4625791_4627078_-|coenzyme-F420-0:L-glutamate-ligase
MWAVGGMPEVRDGDDLAKLIAAAEPGMADGDVLLVTSKIVSKAEGRIVEAADREAAIDAETVRVVARRGTLRIVENRQGLVMAAAGVDASNTPAGTVLLLPEDPDASARTIRDGLRDILGVEVGVVVTDTFGRPWRNGLTDVAIGAAGVRVLDDLRGGTDAYGNPLSATVVATADELASAGDLVKGKAEGLPVAVVRGLPHVVASAGGDEPGARALVRSAADDMFRLGTSEAVREAVTLRRTVREFSDEPVDPGAVRRAVAAAVTAPAPHHTTPWRFVLLESAESRTRLLDAMREAWIEDLRRDGKSEESIAKRVRRGDVLRNAPYLVVPCLVMDGSHTYGDERRDTAEREMFVVAAGAGVQNFLVALAGERLGSAWVSSTMFCRSVVREVLSLPSSWDPLGAVAVGHGVGVPRERAVRSAEAFLTVR
>CP029361.1|AWL88088.1|4624416_4625460_+|DNA-3-methyladenine-glycosylase-2-family-protein
MAGRFAPRTTRAALPHQTVADRAAASGAAASRRQSASAPASPEGPPLTREWTPPAPLDLRLVLGPLRRGPADPTFRMTGDGTFWRATRTPAGPGTLRIARRGDRIAAAAWGPGADWLLEGLPALLGAEDDPDAFVPRHRLLALTRHRRPGLRLLRTGLVLESLIPSVLEQKVTTDEAYRAWRHLVRRFGTPAPGPTADLGLHVMPDPRGWAMIPSWEWHKANVDAKRSSTILRAVRVARRLEEAATMPLPEAQTRLQLIPGIGPWTAAETLQRSNGAADAVTVGDLHLPGIVGHALADNRDADDEEMLRLLTPYEGQRHRATRLILLSGRIPARRAPRMQPGNIVNL
>CP029361.1|AWL88097.1|4638670_4638853_+|hypothetical-protein
MALEAGLLEILACPACHSPLDDRSAADSPELVCTGDDCGLAYPVRDGIPVLLVDEARRPA
>CP029361.1|AWL88098.1|4639012_4640149_+|mannose-6-phosphate-isomerase
MLDESLLDAPEALARADRRDLLRGAAEAGARVRTAARHAAEAGIGGLTPEGRPRAVLFAGPGTAASGVADLIGALAGAAAPVTRIHPTGVAPAPGALRWALPGWAGSVDLLLIATADGSEPGLALLAEQAYRRGCTVVAVAPTRSPLREAVDGVHGLVVPMAAAPHGEYDAETSAAGPGTLWALLTPLLALLDRVGLVTATPEDLQKVADRLDRTAERCGPAIATYSNPAKTLAAELADSLPLLWTEGDAAGPVGRRFAAVLSELAGRPALAAQLPEALPSHGTLLAGDFAAGADPDDFFRDRVEEGETLRARVVLLRDRPTGGLSAYPAARELALGHDTPVSELEPEEGGELEAVAELLAITDFAAVYLSLASAPQP
>CP029361.1|AWL88099.1|4640363_4641539_+|mannose-6-phosphate-isomerase,-class-I
MDRLSNTVRPYAWGSTTAIPALLGIAPTGEPQAEMWMGAHPGAPSRITRTTASGEIELALTEAIDADPEGELGAPTVARFGPRLPFLLKLLAAGAPLSVQVHPDLEQAREGYADEEARGVPIDAPHRTYKDANHKPELICALTPFAGLCGFRPPTEAADAMEALGVDSLKPYVDLLRAHPEEAALREVLTAILGADPAEMTETVTEAAAAAERLGGAHAPYARIAHHFPGDPGVLAAMLLNYVELQPGEALFLGAGVPHAYLDGLGVEIMANSDNVLRCGLTPKHIDVPELLRIVRFEATEPGVLRPEAAPSGEELYETPVDEFALSRYTLASGAAPTDLTAPTPQILLCTAGTVTVGEIALGPGESAYVPADERVEATGPGTLFRATVAA
>CP029361.1|AWL88100.1|4641626_4642613_+|cation-diffusion-facilitator-family-transporter
MSASGGTKAIVAALAANLSIAVAKFVAFLFSGSSSMLAESVHSLADSGNQGLLLLGGKRAKREATPEHPFGYGRERYIYAFLVSIVLFSVGGMFAVYEGYEKIKHPHEIEAWYWPVGVLVFAIIAEIFSFRTAIKESNLTRGDRSWTEFVRRSKAPELPVVLLEDLGALVGLILALGGVGLALATGNGVWDGIGTLCIGILLILIAIVLAVETKSLLLGESAGIEDVQKIKAAVVDGDTVTRIIHMRTLHLGPEELLVAAKIAVRHDETAAEVAEAINAAENRIRDAVPIARVIYLEPDIYNAEAAATGTNPGKTLDGPTEAPSDSGH
>CP029361.1|AWL88101.1|4642890_4644348_+|adenosylhomocysteinase
MTTTTNRQDFKVADLSLAPFGRKEITLAEHEMPGLMSIRKEFAATQPLAGARITGSLHMTVQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAIAVGPNGTPEAPAGVPVFAWKGETLEEYWWCTEQALTWPNTPTGGPNMILDDGGDATLLVHKGVEFEKAGAAPDPSTADSEEYAHILTLLNRTLGEAPQKWTQLASEIRGVTEETTTGVHRLYEMHRDGSLLFPAINVNDAVTKSKFDNKYGCRHSLIDGINRATDVLIGGKTAVVFGYGDVGKGCAESLRGQGARVIITEIDPICALQAAMDGYQVATLDDVVETADIFITTTGNKDIIMAKDMARMKHQAIVGNIGHFDNEIDMAGLARIDGIVKDEVKPQVHTWTFSDGKVLIVLSEGRLLNLGNATGHPSFVMSNSFADQTLAQIELFTKPQEYPTDVYVLPKHLDEKVARLHLDALGVKLTTLRPEQAAYIGVEVEGPYKPDHYRY
>CP029361.1|AWL88102.1|4644552_4645215_+|hypothetical-protein
MPRGRYSLHDLHDHTPLGEEHFHCAPGPSGWRYVSQTTSPSGDHLGSVDLALDELGRPIRLELHAASWQVRGAALEGVTWVRTDPTGSHATEGNVRAHAFAGTSPAFLIAMTRLLRLTPASPTTRVRVVTFTDPVLAPRSVDQSWALMNSEAHPTDNGPLIVDEYQVSALDTGEQHTVHIAGDVVLAAPGIELEHLETPPSPRAYGPDLDKPDTDGPDAD
>CP029361.1|AWL88103.1|4645211_4646228_-|RDD-family-protein
MSELVTGDAVVLGLRPARLPSRALASAIDLAVTFVVFIVVSVVLGIASAALDEAAVAAIGVASFLLVLIGGPVAVETLSRGRSLGKLACGLRVVRDDGGPIRFRHALVRGAMGLVEILLTFGAVASIASLVSARGRRIGDVFAGTLVIRERVAATGRSVAVPPPPPWLVGRFAELDLSGVPDELWSAIRQYLTRMQQLDPGVGRSIAERLAGELVARTGAAAPQGVPAAAFLAAVVHERQSRDARRVFAGPRAGGYVEAPVARMTAGAGGLGAGAGAGAAAGARGSGPVGTGGSVGGPGSIGGGSAGAGTRSGGGGGGAGDDEQRRGGASSAGFAPPG
>CP029361.1|AWL88104.1|4646347_4647355_+|stage-II-sporulation-protein-M
MDLDVFVTAHRTEWDRLEHLLRRGRHLTGAEADELVVLYQRTATHLSLIQSSSSDPLLTGRLTQLVARARSTVTGTRKASWRDAARFLTAGFPAAVYRSRHWWVPTAVLSTVVAALLGWWIGTHPEVQAAIAAPEDLRAMTRPGGEYETYYSSHPAASFAAQVWTNNAQAAALCLVLGAFLCIPVIWILFLNMLNLGVGIGLMSSAGRLDVFLGLVLPHGLLELTAVFVAAGTGLRLGWAVIDPGPLSRRTALAQQGRAALGMAIGLALVLFVSGLIEGFVTPSGLPTWARITIGVVAELAFLAYVYILGGRAARAGDTGDLASVERSAELPTAA
>CP029361.1|AWL88105.1|4653306_4654620_-|DUF58-domain-containing-protein
MALTGRTALLAALGSLPVGILAPSWTGMLAVNAPLSLAILCDYALAAPVRTLRFTRSGDTTVRLGDAAEVQLTVTNASRRRLRAQLRDAWPPSSWASGTERRSSRHTLTVPAGEQRRLVTVLRPTRRGDRQAERITVRSYGPLGLAARQGQHRAPWTVRVLPPFTSRKHLPSRLARLRELDGRTSVLTRGEGTEFDSLRAYVPGDDTRSIDWRATARQSAVAVRTWRPERDRHILIVLDTGRTSAGRVGDVPRLDASMDATLLLTALAMRAGDRVSLLAYDRQVRARVQGRTASGNVLATVINTLATLEPELIETDARGLSNAALTDAPRGSLIVLLTTLEAAPIEEGLLPVLPQLTQRHTVLVAAVSDPRIEEMANARGTVDSVYDAAAAGQAQADRRRTADRLRRHGVVVVDATPDHLAPALADTYLALKAAGRL
>CP029361.1|AWL90531.1|4654630_4655602_-|MoxR-family-ATPase
MPTETEPSDSARASLEALRSEIAKAVVGQDPAVTGLVVALLCRGHVLLEGVPGVAKTLLVRALAASLELNTKRVQFTPDLMPSDVTGSLVYDARTAEFSFQPGPVFTNLLIADEINRTPPKTQSSLLEAMEERQVTVDGTPRPLPEPFLVAATQNPVEYEGTYPLPEAQLDRFLLKLTVPLPSRQDEIDVLTRHADGFNPRDLKAAGIKPVAGPADLEAAREAVAKTTVSPEIAGYVVDICRATRDSPSLALGVSPRGATALLSTARAWAWLTGRDYVIPDDVKALALPTLRHRIQLRPEAEMEGVTPDSVIASVLAHVPVPR

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Crispr_ID: CP029361_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029361_10

5888098-5888257

Orphan

Consensus_repeat	Method
GTCCTCAATCGCCGGACGGGCTGGA	CRISPRCasFinder

2 spacers

The CRISPR arrays of CP029361_10

>merge|CP029361|10|5888098-5888257|CRISPRCasFinder
GTCCTCAATCGCCGGACGGGCTGGAATTGGCCGCCCGGTCCGAGGCCTCGGGTACAGGCGTCCTCAATCGCCGGACGGGCTTGATGTGGCCGGCGTCGTCATCAAGCCCGGGTCTGGGCTTGATGGGGCGACCCGGTCATCACGTGCCGGACGGGCTTGA

>CP029361|10|8|5888098-5888257|CRISPRCasFinder
GTCCTCAATCGCCGGACGGGCTGGA	ATTGGCCGCCCGGTCCGAGGCCTCGGGTACAGGC
GTCCTCAATCGCCGGACGGGCTTGA	TGTGGCCGGCGTCGTCATCAAGCCCGGGTCTGGGCTTGATGGGGCGACCCG
GTCATCACGTGCCGGACGGGCTTGA

Protein	Signature genes	Signature genes Name	Protein_function
CP029361.1\|AWL88993.1\|5896304_5897072_+\|serine-protease	unknown	unknown	gnl\|CDD\|238113
CP029361.1\|AWL88989.1\|5891058_5891808_-\|enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl\|CDD\|181174
CP029361.1\|AWL88987.1\|5889418_5890168_-\|CoA-transferase	unknown	unknown	gnl\|CDD\|224968
CP029361.1\|AWL90619.1\|5899266_5900130_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
CP029361.1\|AWL88980.1\|5881932_5883078_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173841
CP029361.1\|AWL88984.1\|5886028_5886232_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
CP029361.1\|AWL88977.1\|5879724_5880294_+\|HutD-family-protein	unknown	unknown	gnl\|CDD\|377578
CP029361.1\|AWL88979.1\|5880868_5881933_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173838
CP029361.1\|AWL88991.1\|5894308_5895064_-\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|293786
CP029361.1\|AWL88992.1\|5895102_5896020_-\|hypothetical-protein	unknown	unknown	unknown
CP029361.1\|AWL88978.1\|5880349_5880841_+\|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl\|CDD\|274679
CP029361.1\|AWL88976.1\|5878975_5879728_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|378410
CP029361.1\|AWL88981.1\|5883179_5883962_+\|short-chain-dehydrogenase	unknown	unknown	gnl\|CDD\|236110
CP029361.1\|AWL88994.1\|5897217_5899038_-\|beta-galactosidase	unknown	unknown	gnl\|CDD\|366567
CP029361.1\|AWL88986.1\|5888330_5889419_-\|nitronate-monooxygenase	unknown	unknown	gnl\|CDD\|240081
CP029361.1\|AWL88983.1\|5884641_5885799_+\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|181123
CP029361.1\|AWL88982.1\|5884016_5884604_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380061
CP029361.1\|AWL88988.1\|5890164_5891055_-\|CoA-transferase-subunit-A	unknown	unknown	gnl\|CDD\|224702
CP029361.1\|AWL88985.1\|5886417_5888022_+\|ATP-dependent-helicase	unknown	unknown	gnl\|CDD\|223587
CP029361.1\|AWL88990.1\|5891902_5892841_+\|KR-domain-containing-protein	unknown	unknown	gnl\|CDD\|236099

Protein	Function_ID	Function_description	E-value
CP029361.1\|AWL88993.1\|5896304_5897072_+\|serine-protease	gnl\|CDD\|238113	cd00190, Tryp_SPc, Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad residues.	4.55074e-72
CP029361.1\|AWL88989.1\|5891058_5891808_-\|enoyl-CoA-hydratase-family-protein	gnl\|CDD\|181174	PRK07938, PRK07938, enoyl-CoA hydratase family protein.	7.56935e-148
CP029361.1\|AWL88987.1\|5889418_5890168_-\|CoA-transferase	gnl\|CDD\|224968	COG2057, AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit [Lipid metabolism].	1.58748e-28
CP029361.1\|AWL90619.1\|5899266_5900130_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	5.29354e-24
CP029361.1\|AWL88980.1\|5881932_5883078_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	1.73033e-123
CP029361.1\|AWL88984.1\|5886028_5886232_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	6.19581e-36
CP029361.1\|AWL88977.1\|5879724_5880294_+\|HutD-family-protein	gnl\|CDD\|377578	pfam05962, HutD, HutD. HutD from Pseudomonas fluorescens SBW25 is a component of the histidine uptake and utilisation operon. HutD is operonic with the well characterized repressor protein HutC. Genetic analysis using transcriptional fusions (lacZ) and deletion mutants shows that hutD is necessary to maintain fitness in environments replete with histidine. Evidence outlined by Zhang & Rainey (2007) suggests that HutD functions as a governor that sets an upper bound on the level of hut operon transcription. The mechanistic basis is unknown, but in silico molecular docking studies based on the crystal structure of PA5104 (HutD from Pseudomonas aeruginosa) show that urocanate (the first breakdown product of histidine) docks with the active site of HutD.	3.0317e-61
CP029361.1\|AWL88979.1\|5880868_5881933_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	3.01395e-19
CP029361.1\|AWL88991.1\|5894308_5895064_-\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	4.03345e-19
CP029361.1\|AWL88978.1\|5880349_5880841_+\|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl\|CDD\|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	2.51517e-05
CP029361.1\|AWL88976.1\|5878975_5879728_+\|VWA-domain-containing-protein	gnl\|CDD\|378410	pfam10138, vWA-TerF-like, vWA found in TerF C-terminus. vWA domain fused to TerD domain typified by the TerF protein. Some times found as solos.	1.42092e-91
CP029361.1\|AWL88981.1\|5883179_5883962_+\|short-chain-dehydrogenase	gnl\|CDD\|236110	PRK07831, PRK07831, SDR family oxidoreductase.	7.81764e-164
CP029361.1\|AWL88994.1\|5897217_5899038_-\|beta-galactosidase	gnl\|CDD\|366567	pfam01301, Glyco_hydro_35, Glycosyl hydrolases family 35.	1.1716e-126
CP029361.1\|AWL88986.1\|5888330_5889419_-\|nitronate-monooxygenase	gnl\|CDD\|240081	cd04730, NPD_like, 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase family that reduce a range of alternative electron acceptors. Most use FAD/FMN as a cofactor and NAD(P)H as electron donor. Some contain 4Fe-4S cluster to transfer electron from FAD to FMN.	1.45027e-85
CP029361.1\|AWL88983.1\|5884641_5885799_+\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|181123	PRK07801, PRK07801, acetyl-CoA C-acetyltransferase.	0
CP029361.1\|AWL88982.1\|5884016_5884604_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|380061	pfam17932, TetR_C_24, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in family members such as HTH-type transcriptional repressor KstR2 as well as fatty acid metabolism regulator proteins. In Mycobacterium smegmatis, KstR2 is involved in involved in cholesterol catabolism, while YsiA in Bacillus subtilis is involved in fatty acid degradation.	1.57842e-16
CP029361.1\|AWL88988.1\|5890164_5891055_-\|CoA-transferase-subunit-A	gnl\|CDD\|224702	COG1788, AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism].	1.90069e-52
CP029361.1\|AWL88985.1\|5886417_5888022_+\|ATP-dependent-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	7.72715e-122
CP029361.1\|AWL88990.1\|5891902_5892841_+\|KR-domain-containing-protein	gnl\|CDD\|236099	PRK07791, PRK07791, short chain dehydrogenase; Provisional.	4.82301e-153

>CP029361.1|AWL88985.1|5886417_5888022_+|ATP-dependent-helicase
MTSSERSERQDRTPRSRPARGRGRGQGAGSQAPANGRGGAPRSRTQGGSKPAARRKPAVAAPAEFALPETMTPALPSVDAFADLDMPAALLKTLAAQGVTEPFPIQGATLPNSLAGRDILGRGRTGSGKTLAFGLALLARTAGRRSEPRAPLAMVLVPTRELAQQVTDALTPYATAVNLRLATVVGGMSITKQSATLRRGAEVLVATPGRLKDLIERGDCRLDQVAITVLDEADQMADMGFMPQVVALLKQVEADGQRMLFSATLDKNIDRLVKMFLTDPVVHSVDPSAGAVTTMEHHVLHVLDETDKKAVATKIAARDGRVIMFVDTKRAADRFAKRLLASGVRAAALHGGRSQPQRNRTLDQFKNGQVTALVATNVAARGIHVDDLDLVVNVDPPTDHKDYLHRGGRTARAGESGSVVTLVLPDEKREMTRLMQDAGIAPRTTRVTSSDEELSRITGAREPSGVAIVIEVPQPTPPKQRTRSGSGSGGGAVRSGSRGRGRRGSGAGAGAQGGAARSGAPARSGAPARRRRAA
>CP029361.1|AWL88984.1|5886028_5886232_+|cold-shock-protein
MATGTVKWFNSEKGFGFIEQDGGGADVFAHYSNINASGFRELQEGQKVSFDVTQGQKGPQAENIVPV
>CP029361.1|AWL88983.1|5884641_5885799_+|acetyl-CoA-C-acetyltransferase
MTEAYIVEAVRTPVGRRGGGLGAVHPADLGAHVLRELIARSGVDPAAVEDVVFGCLDTVGPQAGDIARTSWLAAGLPEEVPGVTIDRQCGSSQQALHFAAQGVLSGTQDLVVAGGTQNMTQIPIAFASRRAAEPLGLTQGPYAGSEGWRARYGDAPVNQFHGAQLIAEKWGISRRDMEEFALTSHRRAVRALDEGRFARETVAYGNVTADEGPRRDTTLEKMAGLRPVVEGGTVTAACSSQVSDGAAALLIASERAVAEHGLTPRARIHHLSVRGEDPIRMLSAPIPATAHALKKTGLTLDAIDLVEINEAFAPVVLAWLKETGADPERVNVNGGAIALGHPLGATGARLMTTLLHELERTGGRYGLQTMCEGGGQANVTIIERL
>CP029361.1|AWL88982.1|5884016_5884604_+|TetR/AcrR-family-transcriptional-regulator
MTPTPERRRELLATAAEVFAAQGYNATTVRRVADEAGMLAGSLYYHFDSKESMLDEILSTFLDELWQGYDEVLAAGLGPRETIEALVTESFREIDRHRPAVAIYQKESKHLATQPRFAYLADSQTKFEKAWLGTLERGVTEGAFRDDLDIRLTYRFVRDTVWVAASWYRPGGHHSPEEIARQYLSMVLDGIALRT
>CP029361.1|AWL88981.1|5883179_5883962_+|short-chain-dehydrogenase
MSAPPYLPGHGLLTGRTAVVTAAAGAGIGGATARRFLEEGARVVVSDAHARRLKESAHALADTFGPDRVTALTCDVTDEDQVAALFEHTERTHGGLDIVVNNAGLGGTAELTEMTDDQWTKILDVTLNGTFRCTRAALRSLKAAGRGGVVVNNASVVGWRAQRGQAHYAAAKAGVMALTRCAAVEAADYGVRVNAVAPSLAMHPHLAKVTSAELLAELTGKEAFGRYAEPWEVANVIVFLASGYSSYMTGEVVPVSSQHA
>CP029361.1|AWL88980.1|5881932_5883078_-|acyl-CoA-dehydrogenase
MDLEQTARTEALRTEARAWLREHVPARPLPSLETGEGFAAHREWEALLHSGRWSAVSWPEEYGGRGADLFGWLAFEEEYWAAGAPGRVSQNGVSLLAPTLLAHGTAAQRARVLGPMASGEVIWAQAWSEPEAGSDLAALRSRAVRTEGGWLLSGQKTWSSRAAFADRAFGIFRTDPGATKPHQGLTYLMFGLRDPGVTVRPIGRLDGKPAFAEIFLDEVFVPDEDVIGEPGQGWRIAMSATGDERGLTLRSPGRFLAAAGRLRELWRRAGDPADTALRDRVADAVIGARAYQLFTAASASRFAAGAALGPESSLNKVFWSRYDIELHETALDLLGPDAEVADTAWAEGYVFALAGPIYAGTNEIQRDIIAERLLGLPKGRR
>CP029361.1|AWL88979.1|5880868_5881933_-|acyl-CoA-dehydrogenase
MRFLLTDEQREFGRSLDALLTAADTPAVLRAWAAGDHGPGRALWGRLADAGVFALAVPEAYGGVGPLPVEAAVACVELGRHAVPGPVAETLAAGVLLAGAGGPVAEKWLPGIASGAAVVSLTLEGYGPYAPDADAADAVFTVTGDELRLAPGPGEPSASADPARRLFRPEPGGAPVAKGPAIRAAARAAGDTAAFATAALALGCGEELLRATVAYVKQRTQFGVPVGSFQAVKHRLADTLLGLEFARPLLYGAAVELASEVSRPGAGAGAGSAEGSPGAGAGSAEGSSGAGAAVAAAKVAAGEAGYAAARTALQLHGAIGYTEELDLAWWLRRARPLRDVWGTPSACRARVLAG
>CP029361.1|AWL88978.1|5880349_5880841_+|pyridoxamine-5'-phosphate-oxidase-family-protein
MAPMTSSSPLSWDGFATAEPDFADTVQRRFRLYKHHVLATLRKDGSPRVTGLEADFRFGEMLLGMMPDSFKALDLRRDPRFALHANPGPDAEMNDGDVRVSGRAVEITDPEVIARFIEEATPPEPFHLFRTELTEVVRIGLDNDELVIQSWRPGQPLRTVRRK
>CP029361.1|AWL88977.1|5879724_5880294_+|HutD-family-protein
MTVRILRAADLSPAPWKNGGGLTREIATGPEGAGADAFDWRVSLADVTADGPFSAFPGVDRILTVVEGAGMDLVVGGEHHIVDEPLWPHGFPGDLPTEGFLLGGPVVNLNVMYRRARTRAETAVVCGTVRLLPPEGGAVLTVSLDDGAELESVGGGVRLDRYDAVLAAGESPGVLRTMGQAVLITLSGG
>CP029361.1|AWL88976.1|5878975_5879728_+|VWA-domain-containing-protein
MHGVDTAVGRSGPAISLTKVQETAPALVSLYKSAGVSLEKHGLNGHRAAVYLVIDYSGSMKPYYQDGSVQALADRVLGLSANLDDDGTVPVVFFSTDVDAVTDIALDNHHGRIDKIAAGLGHMGKTSYHLAMDAVIDHYLDSGSTAPALVVFQTDGGPINKLAAERYLCKAAKLPLFWQFVGFGNTRSSQFDFLRKLDELAVPAKRPVDNAGYFHAGLDPRKVPDSELYDRLVAEFPLWLAAAREQGIVR
>CP029361.1|AWL88986.1|5888330_5889419_-|nitronate-monooxygenase
MRTALTDLVGVRHPIVQTGMGWVAGPRLVTATARAGALGILASATMTPEQLRSAVREVRSRTDAPFGVNLRSDAGDARERVRIIVEEGVRVASFALAPSRELIAELKDAGVLVVPSVGARRHAEKVAAWGADAVIVQGGEGGGHTGDVATTVLLPQVVDAVDIPVVAAGGFHDGRGLVAALAYGAAGVAMGTRFLLTSDSTVPDAVKARYLAATAKDITLTRAVDGLPHRMLRTEMVAELENGTGRLRALYGAVRRASRFRRLSGLSWPGMVRDGLAMRHGKELSWSQVLLAANTPMLLRAAMVEGRTDLGIMASGQVAALIEDVPSVAGLVERVMADAEGTLAALAAMSSPPGAESSPSGA
>CP029361.1|AWL88987.1|5889418_5890168_-|CoA-transferase
MNASAVESTTRAEYCVIACAEAWRGGGEILASPMGAVPSVGARLARLTFAPDLLLTDGEATLVGPGGEAEGWLPYRRHLALVTGGRRHVMMGASQIDRFGNQNISCIGDWEQPARQLLGVRGAPVNTLNNPVSYWIPRHSPRVFVERVDMICGVGHDSARAAGPSATRFHRIPRVVSDLGVFDFATPDRSMRLASLHPGVTVGQVREATGFALTVPADVPYTRDPSPAELTLIREVVDRARTRDREVRA
>CP029361.1|AWL88988.1|5890164_5891055_-|CoA-transferase-subunit-A
MTTAPYARDKTMTPEEVVDRLSSGMTIGIGGWGSRRKPMALVRALLRSSVTDLTVISYGGPDVGLLAAAGRIRRLVTAFVTLDSIPLEPHYRAARQRGAFALTEIDEAMFMWGLHAAANRLPFLPVRAGLGSDVMRVNPELRTVTSPYEDGEEFVAMPALRMDAALVHLNRADRLGNGRYLGPDPYFDDLFCEAADAAYVSCERLLETRELTEGAGALQTLLVQRHSVTGVVETPGGAHFTSCVPDHPRDEPFQKAYAAAAADPVAWADFAARFLPPDGDEKSYREAVRVWHEEQK
>CP029361.1|AWL88989.1|5891058_5891808_-|enoyl-CoA-hydratase-family-protein
MTVSTSSPSGAGGVRVVTVDRPPVNALPVQGWYDLADAVRAAGRDPEVRCVVLAAEGRGFNAGVDIKELQRDPGHASLIGANRGCAEAFAAVYACEVPVVAAVRGFCLGGGIGLVGNADAIVASEDAVFGLPELDRGALGAATHLARLVPQHLMRTLYYTSRTVTAAELLAHGSVWQVVPSAGLQDAALALAAEIAAKDGHLLRLAKAALNGIDPVDVQRSYRFEQGFTFEANLAGTAARVRDTFGKEA
>CP029361.1|AWL88990.1|5891902_5892841_+|KR-domain-containing-protein
MTAPTAHRAGLCAGRVVAVTGAGRGLGRAHALAFAAEGARVVVNDLGVGPDGGGGERSGGPARAVVDEIVAAGGEAVVHGGDIATAEGAASLVSTALDAFGRLDTLVNNAGFLRDRMLVNLDEDDWDAVVRVHLRGHFLPLKHAAAHWRAETKAGRTPVARVINTSSGAGFLGSVGQGNYAAAKAGIVALTLVAAAELGRYGVHVNALAPAARTRMTERTFAEAMAAPGEGEFDAMAPANVSPLVVWLGSAASDGVTGRVFEAEAGRITVMEGWRPGPTDDRGARRSPAEAGETVRRLLADAEKPGQVYGAS
>CP029361.1|AWL88991.1|5894308_5895064_-|ankyrin-repeat-domain-containing-protein
MTNEPIRDEPSLFDALYEDENTVVRALRAGAPAEASDEEGTTALYTAAVQDRPEMVRLLLVAGADPDRASGPEAGDLPLCGAACGGHTEVVEALLSAGARPDLREEFGFTALRWAVGLGHAATVEALLAGGADPLLPGPQGEAMLVLAAQRGSVRTVRALLAHGAGAEGQESAVASALAEARRIAGLDPERELLRRLEEMYGSGLDTVVLRERRDGEETVAVELLRDGVPSAGVDQHTGHAEIVALLDGRA
>CP029361.1|AWL88992.1|5895102_5896020_-|hypothetical-protein
MGDSGVTNSPPGAPVAHGFPHLETVRSAITALYRRLSADGVRTYATSLAPVDAAFADEDDLHLGAQRVARSLVQHLRLPDARMIVGFRAMEHAASVELTAGPEYFIELNDRFRTHRRDIGAALAHETTHVLLHRLGLEFPGTRANEILTDTTTAYLGTGWLLLDAFREDATSRQKLGYLTPEEFGYVLAKRAFAFDEDPSPWFTSPQAYTAYTKGRQRALDDLRRPPLTAAGWTGRRRYAKDRRYAQDHPGTAPDPSVPYAFETGAEGLRVSFPCPTCHQRIRLPVRGRVSARCGLCRTRLECDT
>CP029361.1|AWL88993.1|5896304_5897072_+|serine-protease
MKLLSALKRCSVAIAAVALATVSLQPASAAPQPIVGGERAEQGEFPFMVRLSMGCGGSLYTQDVVLTAAHCVDGSGDDTSISVTGGVADLESPDAITVNSTKVLQAPGYNGTGKDWALIKLDKPIDQPTLKIATDATYDEGTFTVAGWGADKEGGSQQRHLLKADVPFVSDSDCQGAYSNLVADEELCAGLLDTGGVDSCQGDSGGPMFRKDDSDEWVQVGIVSWGQGCARPNYPGVYTQVSHFAADIASAADSL
>CP029361.1|AWL88994.1|5897217_5899038_-|beta-galactosidase
MTDFTVGDDGFRFEGKPVRLLSGALHYFRVHEEQWEHRLAMLAAMGLNCVETYVPWNLHEPREGEVRDVGALGRFLDAVERAGLWAIVRPGPYICAEWENGGLPVWVTGRFGRRVRTRDAEYRAVVERWFRELLPQVVRRQVVRGGPVILVQAENEYGSFGSDAVYLEWLAGLLRECGVTVPLFTSDGPEDHMLTGGSVPGLLATANFGSGAREGFEVLRRHQPKGPLMCMEFWCGWFDHWGAEPVLRDAEQAAGALREILECGASVNIYMAHGGTNFAGWAGANRGGPLQDGEFQPTVTSYDYDAPVDEYGRATEKFHLFRKVLEGYAQGPLPELPPEPKGLAVPVRAELTGWAGLGDVLEALGGPETESGVPPTFEELGVDRGLVRYRVAVPGPRQAYPLGASGLRDRAVVYVDGVRAGVLTEESGTLPEPVAGPAEVELWVESLGRVNYGPRLGEPKGVTGGVLHERQYLHGVRARGLRLDAFETPGAVAALPFGPVEAAAGAGDAGRTGLFRGAFTVEGAAGLGHAGLELPGWTRGFVWVNGFCLGRYWSAGPQRTLYVPGPVLREGANEVWVLELEDAGGPWVELGPGVPVRAGTPGVVQR
>CP029361.1|AWL90619.1|5899266_5900130_+|AraC-family-transcriptional-regulator
MRFFTPSPLHHRLGLVCLGVGLQHGALPTVGPRTLDHHVAVIVNSGTGWFKGPDGRRTPVTGPSLIWLTPGTPHHYGADPGTGWDESFVDFTGPATATYTELGYIEPERPLVPLADTAAPRAAVGRIVRAARRGNPLLEVETGAAVHELLVSLRRARADIGPDGDPVLQALARDAYQPLTVAQHASRHGMTPAELRTAVRRGAGCSPKDYLLGIRLGRAKELLAATDLPVAAVARRVGYDDPAYFSRLFARRVGTAPVRFREQQGRSVPGGWSDRVPDPDDPPTIGP

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP029361_9	9.2\|5395098\|38\|CP029361\|CRT	5395098-5395135	38	CP029361.1	5394825-5394862	1	0.974
CP029361_9	9.2\|5395098\|38\|CP029361\|CRT	5395098-5395135	38	CP029361.1	5395185-5395222	1	0.974
CP029361_7	7.1\|4235782\|15\|CP029361\|CRISPRCasFinder	4235782-4235796	15	CP029362.1	123004-123018	2	0.867

1. spacer 9.2|5395098|38|CP029361|CRT matches to position: 5394825-5394862, mismatch: 1, identity: 0.974

caggaggccaaggagaaggaggcggagcagaagcaggc	CRISPR spacer
caggaggccaaggagaaggaggcggagcagaagcaagc	Protospacer
***********************************.**

2. spacer 9.2|5395098|38|CP029361|CRT matches to position: 5395185-5395222, mismatch: 1, identity: 0.974

caggaggccaaggagaaggaggcggagcagaagcaggc	CRISPR spacer
caggaggccaaggagaaggaggccgagcagaagcaggc	Protospacer
*********************** **************

3. spacer 7.1|4235782|15|CP029361|CRISPRCasFinder matches to position: 123004-123018, mismatch: 2, identity: 0.867

cgcggaacgctgctg	CRISPR spacer
cgcggaactcggctg	Protospacer
******** * ****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP029361_9	9.3\|5395158\|23\|CP029361\|CRT	5395158-5395180	23	KT716399	Pseudomonas phage POR1, complete genome	6459-6481	1	0.957
CP029361_1	1.3\|413585\|22\|CP029361\|CRISPRCasFinder	413585-413606	22	NZ_CP011869	Pseudonocardia sp. HH130629-09 plasmid pLS1-1, complete sequence	54518-54539	2	0.909
CP029361_9	9.3\|5395158\|23\|CP029361\|CRT	5395158-5395180	23	NZ_CP018077	Sulfitobacter sp. AM1-D1 plasmid unnamed1, complete sequence	96653-96675	2	0.913
CP029361_9	9.3\|5395158\|23\|CP029361\|CRT	5395158-5395180	23	MN857473	Teseptimavirus S2B, complete genome	30216-30238	2	0.913
CP029361_9	9.3\|5395158\|23\|CP029361\|CRT	5395158-5395180	23	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1096378-1096400	3	0.87
CP029361_9	9.3\|5395158\|23\|CP029361\|CRT	5395158-5395180	23	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	215874-215896	3	0.87
CP029361_9	9.3\|5395158\|23\|CP029361\|CRT	5395158-5395180	23	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	595233-595255	3	0.87
CP029361_9	9.3\|5395158\|23\|CP029361\|CRT	5395158-5395180	23	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1408959-1408981	3	0.87
CP029361_9	9.3\|5395158\|23\|CP029361\|CRT	5395158-5395180	23	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1298155-1298177	3	0.87
CP029361_9	9.3\|5395158\|23\|CP029361\|CRT	5395158-5395180	23	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	126130-126152	3	0.87
CP029361_9	9.3\|5395158\|23\|CP029361\|CRT	5395158-5395180	23	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	453382-453404	3	0.87
CP029361_4	4.1\|3184755\|25\|CP029361\|CRT	3184755-3184779	25	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	434181-434205	4	0.84
CP029361_4	4.1\|3184755\|25\|CP029361\|CRT	3184755-3184779	25	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	434181-434205	4	0.84
CP029361_4	4.1\|3184755\|25\|CP029361\|CRT	3184755-3184779	25	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	434193-434217	4	0.84
CP029361_4	4.1\|3184755\|25\|CP029361\|CRT	3184755-3184779	25	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	434214-434238	4	0.84
CP029361_4	4.1\|3184755\|25\|CP029361\|CRT	3184755-3184779	25	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	434180-434204	4	0.84
CP029361_4	4.3\|3184855\|25\|CP029361\|CRT	3184855-3184879	25	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	662211-662235	4	0.84
CP029361_4	4.3\|3184855\|25\|CP029361\|CRT	3184855-3184879	25	NZ_CP011523	Streptomyces sp. CFMR 7 strain CFMR-7 plasmid unnamed, complete sequence	31939-31963	4	0.84
CP029361_9	9.1\|5395050\|26\|CP029361\|CRT	5395050-5395075	26	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	515307-515332	4	0.846
CP029361_9	9.1\|5395050\|26\|CP029361\|CRT	5395050-5395075	26	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	253828-253853	4	0.846
CP029361_9	9.1\|5395050\|26\|CP029361\|CRT	5395050-5395075	26	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	19841-19866	4	0.846
CP029361_9	9.1\|5395050\|26\|CP029361\|CRT	5395050-5395075	26	NZ_CP041605	Streptomyces sp. S1D4-14 plasmid pS1D4-14.1, complete sequence	65522-65547	5	0.808
CP029361_9	9.1\|5395050\|26\|CP029361\|CRT	5395050-5395075	26	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1305048-1305073	5	0.808
CP029361_9	9.1\|5395050\|26\|CP029361\|CRT	5395050-5395075	26	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	1085139-1085164	5	0.808
CP029361_9	9.1\|5395050\|26\|CP029361\|CRT	5395050-5395075	26	NZ_CP026653	Streptomyces dengpaensis strain XZHG99 plasmid unnamed1, complete sequence	46057-46082	5	0.808
CP029361_9	9.1\|5395050\|26\|CP029361\|CRT	5395050-5395075	26	NZ_LR594664	Variovorax sp. RA8 plasmid 3	417600-417625	5	0.808
CP029361_3	3.1\|2963801\|29\|CP029361\|CRISPRCasFinder	2963801-2963829	29	NZ_CP054028	Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence	249055-249083	6	0.793
CP029361_3	3.1\|2963801\|29\|CP029361\|CRISPRCasFinder	2963801-2963829	29	NZ_CP021032	Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence	114084-114112	6	0.793
CP029361_3	3.1\|2963801\|29\|CP029361\|CRISPRCasFinder	2963801-2963829	29	MN234166	Gordonia phage ASerpRocky, complete genome	13004-13032	7	0.759
CP029361_3	3.1\|2963801\|29\|CP029361\|CRISPRCasFinder	2963801-2963829	29	NC_019790	Deinococcus peraridilitoris DSM 19664 plasmid pDEIPE02, complete sequence	36959-36987	8	0.724
CP029361_3	3.1\|2963801\|29\|CP029361\|CRISPRCasFinder	2963801-2963829	29	MN694573	Marine virus AFVG_250M323, complete genome	19985-20013	8	0.724
CP029361_10	10.1\|5888123\|34\|CP029361\|CRISPRCasFinder	5888123-5888156	34	NZ_LR134461	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 19, complete sequence	25827-25860	8	0.765
CP029361_4	4.2\|3184799\|37\|CP029361\|CRT	3184799-3184835	37	NZ_CP024891	Rhodococcus ruber strain YYL plasmid pYYL1.2, complete sequence	2225-2261	10	0.73
CP029361_4	4.2\|3184799\|37\|CP029361\|CRT	3184799-3184835	37	NZ_CP024891	Rhodococcus ruber strain YYL plasmid pYYL1.2, complete sequence	35057-35093	10	0.73
CP029361_9	9.2\|5395098\|38\|CP029361\|CRT	5395098-5395135	38	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	76347-76384	10	0.737

1. spacer 9.3|5395158|23|CP029361|CRT matches to KT716399 (Pseudomonas phage POR1, complete genome) position: , mismatch: 1, identity: 0.957

gcgaaggaagccgaggccaaggc	CRISPR spacer
gcgaagaaagccgaggccaaggc	Protospacer
******.****************

2. spacer 1.3|413585|22|CP029361|CRISPRCasFinder matches to NZ_CP011869 (Pseudonocardia sp. HH130629-09 plasmid pLS1-1, complete sequence) position: , mismatch: 2, identity: 0.909

cggggtgcgtcggccggcccgg	CRISPR spacer
gggggtgcgtcggccggcccgt	Protospacer
 ********************

3. spacer 9.3|5395158|23|CP029361|CRT matches to NZ_CP018077 (Sulfitobacter sp. AM1-D1 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.913

gcgaaggaagccgaggccaaggc	CRISPR spacer
gccaaggaagccaaggccaaggc	Protospacer
** *********.**********

4. spacer 9.3|5395158|23|CP029361|CRT matches to MN857473 (Teseptimavirus S2B, complete genome) position: , mismatch: 2, identity: 0.913

gcgaaggaagccgaggccaaggc	CRISPR spacer
gcaaaggaggccgaggccaaggc	Protospacer
**.*****.**************

5. spacer 9.3|5395158|23|CP029361|CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 3, identity: 0.87

gcgaaggaagccgaggccaaggc	CRISPR spacer
cggaaggaagccgaggccgaggc	Protospacer
  ****************.****

6. spacer 9.3|5395158|23|CP029361|CRT matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 3, identity: 0.87

gcgaaggaagccgaggccaaggc	CRISPR spacer
ctgacggaagccgaggccaaggc	Protospacer
 .** ******************

7. spacer 9.3|5395158|23|CP029361|CRT matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 3, identity: 0.87

gcgaaggaagccgaggccaaggc	CRISPR spacer
cggaaggaagccgaggccgaggc	Protospacer
  ****************.****

8. spacer 9.3|5395158|23|CP029361|CRT matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 3, identity: 0.87

gcgaaggaagccgaggccaaggc	CRISPR spacer
cggaaggaagccgaggccgaggc	Protospacer
  ****************.****

9. spacer 9.3|5395158|23|CP029361|CRT matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 3, identity: 0.87

gcgaaggaagccgaggccaaggc	CRISPR spacer
cggaaggaagccgaggccgaggc	Protospacer
  ****************.****

10. spacer 9.3|5395158|23|CP029361|CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 3, identity: 0.87

gcgaaggaagccgaggccaaggc	CRISPR spacer
cggaaggaagccgaggccgaggc	Protospacer
  ****************.****

11. spacer 9.3|5395158|23|CP029361|CRT matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 3, identity: 0.87

gcgaaggaagccgaggccaaggc	CRISPR spacer
cggaaggaagccgaggccgaggc	Protospacer
  ****************.****

12. spacer 4.1|3184755|25|CP029361|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

tgaagcaggtccggccccgcgcagc	CRISPR spacer
gcaagcagttccggccgcgcgcagc	Protospacer
  ****** ******* ********

13. spacer 4.1|3184755|25|CP029361|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 4, identity: 0.84

tgaagcaggtccggccccgcgcagc	CRISPR spacer
gcaagcagttccggccgcgcgcagc	Protospacer
  ****** ******* ********

14. spacer 4.1|3184755|25|CP029361|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

tgaagcaggtccggccccgcgcagc	CRISPR spacer
gcaagcagttccggccgcgcgcagc	Protospacer
  ****** ******* ********

15. spacer 4.1|3184755|25|CP029361|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

tgaagcaggtccggccccgcgcagc	CRISPR spacer
gcaagcagttccggccgcgcgcagc	Protospacer
  ****** ******* ********

16. spacer 4.1|3184755|25|CP029361|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

tgaagcaggtccggccccgcgcagc	CRISPR spacer
gcaagcagttccggccgcgcgcagc	Protospacer
  ****** ******* ********

17. spacer 4.3|3184855|25|CP029361|CRT matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 4, identity: 0.84

cgaagctggtccggccccgcgcgaa	CRISPR spacer
cgaagccggtccggccgcgcgcgtt	Protospacer
******.********* ******

18. spacer 4.3|3184855|25|CP029361|CRT matches to NZ_CP011523 (Streptomyces sp. CFMR 7 strain CFMR-7 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

cgaagctggtccggccccgcgcgaa	CRISPR spacer
cgaaggtggtccggccccgggcggc	Protospacer
***** ************* ***.

19. spacer 9.1|5395050|26|CP029361|CRT matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 4, identity: 0.846

caggccagggccgaacaggaggccaa	CRISPR spacer
ccggccagcgccgaccaggaggccat	Protospacer
* ****** ***** **********

20. spacer 9.1|5395050|26|CP029361|CRT matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 4, identity: 0.846

caggccagggccgaacaggaggccaa	CRISPR spacer
ccggccagcgccgaccaggaggccat	Protospacer
* ****** ***** **********

21. spacer 9.1|5395050|26|CP029361|CRT matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 4, identity: 0.846

caggccagggccgaacaggaggccaa	CRISPR spacer
ccggccagcgccgaccaggaggccat	Protospacer
* ****** ***** **********

22. spacer 9.1|5395050|26|CP029361|CRT matches to NZ_CP041605 (Streptomyces sp. S1D4-14 plasmid pS1D4-14.1, complete sequence) position: , mismatch: 5, identity: 0.808

caggccagggccgaacaggaggccaa	CRISPR spacer
aaggccagggccgaactggaggctgc	Protospacer
 *************** ******..

23. spacer 9.1|5395050|26|CP029361|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 5, identity: 0.808

caggccagggccgaacaggaggccaa	CRISPR spacer
gaggccgaggccgaacaggaggccgg	Protospacer
 *****..****************..

24. spacer 9.1|5395050|26|CP029361|CRT matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

caggccagggccgaacaggaggccaa	CRISPR spacer
acggccagggcggaacaggtggccag	Protospacer
  ********* ******* *****.

25. spacer 9.1|5395050|26|CP029361|CRT matches to NZ_CP026653 (Streptomyces dengpaensis strain XZHG99 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

caggccagggccgaacaggaggccaa	CRISPR spacer
aacgccagggccgaactggaggccgc	Protospacer
 * ************* *******.

26. spacer 9.1|5395050|26|CP029361|CRT matches to NZ_LR594664 (Variovorax sp. RA8 plasmid 3) position: , mismatch: 5, identity: 0.808

caggccagggccgaacaggaggccaa	CRISPR spacer
atcgccaggctcgaacaggaggccaa	Protospacer
   ****** .***************

27. spacer 3.1|2963801|29|CP029361|CRISPRCasFinder matches to NZ_CP054028 (Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence) position: , mismatch: 6, identity: 0.793

aatcacgcagcctcgccgccctcccgagg	CRISPR spacer
catcacgcaacctcgccgccctggagcgg	Protospacer
 ********.************   * **

28. spacer 3.1|2963801|29|CP029361|CRISPRCasFinder matches to NZ_CP021032 (Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence) position: , mismatch: 6, identity: 0.793

aatcacgcagcctcgccgccctcccgagg	CRISPR spacer
catcacgcaacctcgccgccctggagcgg	Protospacer
 ********.************   * **

29. spacer 3.1|2963801|29|CP029361|CRISPRCasFinder matches to MN234166 (Gordonia phage ASerpRocky, complete genome) position: , mismatch: 7, identity: 0.759

aatcacgcagcctcgccgccctcccgagg	CRISPR spacer
tcgcgcgcagcctcggcaccctcccgagc	Protospacer
   *.********** *.**********

30. spacer 3.1|2963801|29|CP029361|CRISPRCasFinder matches to NC_019790 (Deinococcus peraridilitoris DSM 19664 plasmid pDEIPE02, complete sequence) position: , mismatch: 8, identity: 0.724

aatcacgcagcctcgccgccctcccgagg	CRISPR spacer
tttcacgcagcctcgccgacctcgtccgc	Protospacer
  **************** **** .  *

31. spacer 3.1|2963801|29|CP029361|CRISPRCasFinder matches to MN694573 (Marine virus AFVG_250M323, complete genome) position: , mismatch: 8, identity: 0.724

aatcacgcagcctcgccgccctcccgagg	CRISPR spacer
gtgagcgcagcctcgccgcgctcccgggc	Protospacer
.   .************** ******.*

32. spacer 10.1|5888123|34|CP029361|CRISPRCasFinder matches to NZ_LR134461 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 19, complete sequence) position: , mismatch: 8, identity: 0.765

attggccgcccggtccgaggcctcgggtacaggc	CRISPR spacer
catggccgcccggtccgtgccctcggggagcagc	Protospacer
  *************** * ******* *  .**

33. spacer 4.2|3184799|37|CP029361|CRT matches to NZ_CP024891 (Rhodococcus ruber strain YYL plasmid pYYL1.2, complete sequence) position: , mismatch: 10, identity: 0.73

cgaagcgaggccgccccggggtccggccccgcgcacg	CRISPR spacer
cggccgccggccgcaccgggggccggccccgcgccct	Protospacer
**.     ****** ****** ************ *

34. spacer 4.2|3184799|37|CP029361|CRT matches to NZ_CP024891 (Rhodococcus ruber strain YYL plasmid pYYL1.2, complete sequence) position: , mismatch: 10, identity: 0.73

cgaagcgaggccgccccggggtccggccccgcgcacg	CRISPR spacer
cggccgccggccgcaccgggggccggccccgcgccct	Protospacer
**.     ****** ****** ************ *

35. spacer 9.2|5395098|38|CP029361|CRT matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 10, identity: 0.737

caggaggccaaggagaaggaggcggagcagaagcaggc--	CRISPR spacer
tggcaggccaaggagaaggaggccgag--gagaccgtccg	Protospacer
..* ******************* ***  **..* * *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1887508 : 1959676

uncultured_Caudovirales_phage(11.11%)

holin,plate,tail,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWL85932.1\|1887508_1889611_-\|holin	phospholipase C, phosphocholine-specific	NA	NA	NA	NA
AWL90329.1\|1889745_1891005_-	arsenic transporter	A0A2H4J144	uncultured_Caudovirales_phage	1.8e-20	27.4
AWL85933.1\|1891100_1892609_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
AWL85934.1\|1892625_1892859_-	hypothetical protein	NA	NA	NA	NA
AWL85935.1\|1892864_1894358_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
AWL85936.1\|1894363_1894660_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase GatCAB subunit C	NA	NA	NA	NA
AWL85937.1\|1894776_1896969_-	bifunctional diguanylate cyclase/phosphodiesterase	NA	NA	NA	NA
AWL85938.1\|1897329_1899561_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	7.6e-99	33.9
AWL85939.1\|1899593_1900622_-	methionine synthase	NA	NA	NA	NA
AWL85940.1\|1900669_1901359_-	short chain dehydrogenase	NA	NA	NA	NA
AWL85941.1\|1901442_1901982_-	TIGR00730 family Rossman fold protein	NA	NA	NA	NA
AWL85942.1\|1902087_1902423_+	DUF427 domain-containing protein	NA	NA	NA	NA
AWL85943.1\|1902498_1903302_+	hydrolase	NA	NA	NA	NA
AWL85944.1\|1903376_1904513_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
AWL85945.1\|1904574_1905312_+	N-acetylmuramoyl-L-alanine amidase	B1ABI9	Lactococcus_phage	2.3e-07	31.3
AWL85946.1\|1905334_1906504_-	cysteine desulfurase	NA	NA	NA	NA
AWL85947.1\|1906679_1907057_-	hypothetical protein	NA	NA	NA	NA
AWL85948.1\|1907408_1908059_+	TetR family transcriptional regulator	NA	NA	NA	NA
AWL85949.1\|1908108_1908507_-	hypothetical protein	NA	NA	NA	NA
AWL85950.1\|1908598_1909222_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AWL85951.1\|1909404_1911057_-	MFS transporter	NA	NA	NA	NA
AWL85952.1\|1911069_1912137_-	hypothetical protein	NA	NA	NA	NA
AWL85953.1\|1912386_1913277_-	thioesterase family protein	NA	NA	NA	NA
AWL85954.1\|1913354_1914026_-	trimeric intracellular cation channel family protein	NA	NA	NA	NA
AWL85955.1\|1914055_1915342_-	ABC transporter ATP-binding protein	M1IB70	Acanthocystis_turfacea_Chlorella_virus	6.1e-08	24.6
AWL85956.1\|1915338_1916331_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	8.2e-13	28.0
AWL85957.1\|1916337_1917300_-	ABC transporter permease	NA	NA	NA	NA
AWL85958.1\|1917301_1918306_-	ABC transporter permease	NA	NA	NA	NA
AWL85959.1\|1918391_1920062_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
AWL85960.1\|1920314_1921103_-	enhanced serine sensitivity protein SseB	NA	NA	NA	NA
AWL85961.1\|1921291_1922062_-	enhanced serine sensitivity protein SseB	NA	NA	NA	NA
AWL90330.1\|1922151_1922823_-	ATP-binding protein	NA	NA	NA	NA
AWL85962.1\|1923302_1924418_+	glycine cleavage system aminomethyltransferase GcvT	NA	NA	NA	NA
AWL85963.1\|1924540_1924918_+	glycine cleavage system protein H	NA	NA	NA	NA
AWL85964.1\|1924937_1926197_+	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	4.3e-91	48.8
AWL85965.1\|1926367_1927753_+	L-serine ammonia-lyase	NA	NA	NA	NA
AWL85966.1\|1927992_1928265_+	hypothetical protein	NA	NA	NA	NA
AWL85967.1\|1928261_1928654_+	PIN domain-containing protein	NA	NA	NA	NA
AWL85968.1\|1928742_1929249_-	cupin domain-containing protein	NA	NA	NA	NA
AWL90331.1\|1929715_1932487_+	LuxR family transcriptional regulator	NA	NA	NA	NA
AWL85969.1\|1932519_1932843_-	hypothetical protein	NA	NA	NA	NA
AWL85970.1\|1934496_1935696_+	S1 family peptidase	NA	NA	NA	NA
AWL85971.1\|1935881_1937321_+	amino acid permease	NA	NA	NA	NA
AWL85972.1\|1937369_1938626_+	arginine deiminase	NA	NA	NA	NA
AWL85973.1\|1938728_1940852_-	ATP-binding protein	A0A2H4UTU5	Bodo_saltans_virus	1.4e-06	30.6
AWL85974.1\|1940848_1941553_-	DUF4255 domain-containing protein	NA	NA	NA	NA
AWL85975.1\|1941549_1944819_-	DUF11 domain-containing protein	NA	NA	NA	NA
AWL85976.1\|1944968_1945691_-	DNA-binding response regulator	NA	NA	NA	NA
AWL85977.1\|1945928_1947278_+	hydrolytic protein	NA	NA	NA	NA
AWL85978.1\|1948020_1949562_+\|tail	phage tail protein	J9PVC2	Bacillus_phage	1.8e-70	34.3
AWL85979.1\|1949624_1950065_+\|tail	phage tail protein	NA	NA	NA	NA
AWL85980.1\|1950061_1950565_+	hypothetical protein	NA	NA	NA	NA
AWL85981.1\|1952595_1952961_-	hypothetical protein	NA	NA	NA	NA
AWL90332.1\|1953238_1953808_+	hypothetical protein	NA	NA	NA	NA
AWL85982.1\|1953896_1954322_+\|tail	phage tail protein	NA	NA	NA	NA
AWL85983.1\|1954377_1955100_+	LysM domain-containing protein	NA	NA	NA	NA
AWL85984.1\|1955096_1956878_+	type IV secretion protein Rhs	NA	NA	NA	NA
AWL85985.1\|1956939_1957257_+	hypothetical protein	NA	NA	NA	NA
AWL85986.1\|1957253_1957715_+\|plate	baseplate protein	A0A0E3F3H3	Synechococcus_phage	1.8e-10	38.6
AWL85987.1\|1957714_1959676_+\|plate	putative baseplate assembly protein	NA	NA	NA	NA

DBSCAN-SWA_2

6147347 : 6154170

Streptomyces_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWL89200.1\|6147347_6148004_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	8.1e-09	29.7
AWL89201.1\|6148003_6149317_+	rRNA pseudouridine synthase	NA	NA	NA	NA
AWL89202.1\|6149442_6150099_+	nicotinamide riboside transporter PnuC	A0A0F6YPU8	Sinorhizobium_phage	1.3e-11	29.2
AWL89203.1\|6150095_6151175_+	transcriptional regulator	A0A2K8HHU5	Bacteriophage	6.2e-30	30.9
AWL89204.1\|6151171_6151936_+	NUDIX hydrolase	A0A0E3JJF3	Streptomyces_phage	1.5e-22	49.3
AWL89205.1\|6151932_6152958_+	ADP-ribosylglycohydrolase family protein	A0A2D0ZND4	Rhodococcus_phage	6.3e-32	33.1
AWL90633.1\|6153020_6153464_+	cyclase	NA	NA	NA	NA
AWL89206.1\|6153429_6154170_-	nucleotidyltransferase	A0A1J0GW18	Streptomyces_phage	7.8e-16	37.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP029362

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP029361

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection