CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP029490	Streptococcus sobrinus strain SL1 chromosome, complete genome	1 crisprs	DEDDh,cas3,csa3,RT,DinG	0	1	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP029490_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029490_1

171961-172031

Orphan

Consensus_repeat	Method
GGTTCGGGGAACCTTTTTATCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029490_1

>merge|CP029490|1|171961-172031|CRISPRCasFinder
GGTTCGGGGAACCTTTTTATCCCGAGCTTGAAAACTGGGAAGCGAGGCGGTTTGGGGAACCTTTTTATCCC

>CP029490|1|1|171961-172031|CRISPRCasFinder
GGTTCGGGGAACCTTTTTATCCC	GAGCTTGAAAACTGGGAAGCGAGGC
GGTTTGGGGAACCTTTTTATCCC

Protein	Signature genes	Signature genes Name	Protein_function
CP029490.1\|AWN20007.1\|162009_162276_+\|ACT-domain-containing-protein	unknown	unknown	gnl\|CDD\|178923
CP029490.1\|AWN20016.1\|172523_173660_+\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|237653
CP029490.1\|AWN20009.1\|164192_165128_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
CP029490.1\|AWN20019.1\|175549_176020_+\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|227064
CP029490.1\|AWN20022.1\|177831_179115_+\|trigger-factor	unknown	unknown	gnl\|CDD\|234956
CP029490.1\|AWN20021.1\|176740_177589_-\|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl\|CDD\|223740
CP029490.1\|AWN20010.1\|165318_165750_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
CP029490.1\|AWN20018.1\|174798_175560_+\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	unknown	unknown	gnl\|CDD\|183513
CP029490.1\|AWN20015.1\|169313_169865_+\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|237628
CP029490.1\|AWN20014.1\|168259_169294_+\|heat-inducible-transcriptional-repressor-HrcA	unknown	unknown	gnl\|CDD\|234621
CP029490.1\|AWN20011.1\|165888_166590_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
CP029490.1\|AWN20013.1\|167508_168093_+\|N-acetyl-muramidase	unknown	unknown	gnl\|CDD\|224619
CP029490.1\|AWN20025.1\|180911_182516_+\|CTP-synthase	unknown	unknown	gnl\|CDD\|235437
CP029490.1\|AWN20008.1\|162287_163625_+\|PFL-family-protein	unknown	unknown	gnl\|CDD\|180009
CP029490.1\|AWN20017.1\|174059_174833_+\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
CP029490.1\|AWN20023.1\|179308_179947_+\|haloacid-dehalogenase	unknown	unknown	gnl\|CDD\|319859
CP029490.1\|AWN21763.1\|170121_171957_+\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
CP029490.1\|AWN20020.1\|176028_176592_+\|TIGR01440-family-protein	unknown	unknown	gnl\|CDD\|237472
CP029490.1\|AWN20012.1\|166576_167344_+\|D-alanyl-D-alanine-carboxypeptidase-family-protein	unknown	unknown	gnl\|CDD\|367124
CP029490.1\|AWN20024.1\|180037_180619_+\|DNA-directed-RNA-polymerase-subunit-delta	unknown	unknown	gnl\|CDD\|225880

Protein	Function_ID	Function_description	E-value
CP029490.1\|AWN20007.1\|162009_162276_+\|ACT-domain-containing-protein	gnl\|CDD\|178923	PRK00194, PRK00194, ACT domain-containing protein.	7.95131e-41
CP029490.1\|AWN20016.1\|172523_173660_+\|molecular-chaperone-DnaJ	gnl\|CDD\|237653	PRK14276, PRK14276, chaperone protein DnaJ; Provisional.	0
CP029490.1\|AWN20009.1\|164192_165128_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	1.37168e-104
CP029490.1\|AWN20019.1\|175549_176020_+\|ECF-transporter-S-component	gnl\|CDD\|227064	COG4720, COG4720, Predicted membrane protein [Function unknown].	1.18268e-28
CP029490.1\|AWN20022.1\|177831_179115_+\|trigger-factor	gnl\|CDD\|234956	PRK01490, tig, trigger factor; Provisional.	1.03145e-160
CP029490.1\|AWN20021.1\|176740_177589_-\|mechanosensitive-ion-channel-family-protein	gnl\|CDD\|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	1.12378e-40
CP029490.1\|AWN20010.1\|165318_165750_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.14951e-14
CP029490.1\|AWN20018.1\|174798_175560_+\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	gnl\|CDD\|183513	PRK12413, PRK12413, bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase.	2.70052e-150
CP029490.1\|AWN20015.1\|169313_169865_+\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|237628	PRK14156, PRK14156, heat shock protein GrpE; Provisional.	5.3205e-87
CP029490.1\|AWN20014.1\|168259_169294_+\|heat-inducible-transcriptional-repressor-HrcA	gnl\|CDD\|234621	PRK00082, hrcA, heat-inducible transcription repressor; Provisional.	7.40319e-106
CP029490.1\|AWN20011.1\|165888_166590_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	1.99833e-48
CP029490.1\|AWN20013.1\|167508_168093_+\|N-acetyl-muramidase	gnl\|CDD\|224619	COG1705, FlgJ, Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion].	2.69131e-38
CP029490.1\|AWN20025.1\|180911_182516_+\|CTP-synthase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
CP029490.1\|AWN20008.1\|162287_163625_+\|PFL-family-protein	gnl\|CDD\|180009	PRK05313, PRK05313, hypothetical protein; Provisional.	0
CP029490.1\|AWN20017.1\|174059_174833_+\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	1.10115e-128
CP029490.1\|AWN20023.1\|179308_179947_+\|haloacid-dehalogenase	gnl\|CDD\|319859	cd16423, HAD_BPGM-like, uncharacterized subfamily of beta-phosphoglucomutase-like family, similar to uncharacterized Bacillus subtilis YhcW. This subfamily includes the uncharacterized Bacillus subtilis YhcW. It belongs to the beta-phosphoglucomutase-like family whose other members include Lactococcus lactis beta-PGM, a mutase which catalyzes the interconversion of beta-D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), Saccharomyces cerevisiae phosphatases GPP1 and GPP2 that dephosphorylate DL-glycerol-3-phosphate and DOG1 and DOG2 that dephosphorylate 2-deoxyglucose-6-phosphate, and Escherichia coli 6-phosphogluconate phosphatase YieH. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.73093e-33
CP029490.1\|AWN21763.1\|170121_171957_+\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
CP029490.1\|AWN20020.1\|176028_176592_+\|TIGR01440-family-protein	gnl\|CDD\|237472	PRK13690, PRK13690, hypothetical protein; Provisional.	5.65217e-107
CP029490.1\|AWN20012.1\|166576_167344_+\|D-alanyl-D-alanine-carboxypeptidase-family-protein	gnl\|CDD\|367124	pfam02557, VanY, D-alanyl-D-alanine carboxypeptidase.	1.42807e-50
CP029490.1\|AWN20024.1\|180037_180619_+\|DNA-directed-RNA-polymerase-subunit-delta	gnl\|CDD\|225880	COG3343, RpoE, DNA-directed RNA polymerase, delta subunit [Transcription].	1.06384e-30

>CP029490.1|AWN21763.1|170121_171957_+|molecular-chaperone-DnaK
MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKNGEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAEDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTEKDEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDYLVDEFKKENGIDLSTDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGDAGPLHLEVSLTRAKFDDLTRDLVDRTKTPVRRALSDAGLSLSEIDEVILVGGSTRIPAVVEVVKAETGKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGVPQIEVTFDIDKNGIVSVKAKDLGTQKEQHIVIKSNDGLSEDEIERMMKDAEANADADAKRKEEVDLKNEVDQAIFATEKTIKETEGKGFDTERDAAKTALDDLKKAQESGNTDDMKAKLETLNEKAQALAVKLYEQAAAAQQAAGGDQAADANDAGSKDSGDDVVDGEFTEK
>CP029490.1|AWN20015.1|169313_169865_+|nucleotide-exchange-factor-GrpE
MSEDIKKEKEEDVTQEAPSSEAEEKQQAQEATPEEATEKTELAAALEKVEDFENKFLRAHAEMQNIQRRANEERQQLQKYRSQDLAKGVLPSLDNLERALAVEGLSDDVKKGIEMVQESLLQALKEEGVEEVPVDSFDHNFHMAVQTLPADDDHPADSIAQVLQKGYQLHDRLLRPAMVVVYN
>CP029490.1|AWN20014.1|168259_169294_+|heat-inducible-transcriptional-repressor-HrcA
MITQRQNDILSIIVELFTQTHEPVGSKALQAYISTSSATIRNDMAILEKIGLLEKAHTSSGRLPSRQGFQYYVSHLLNLESVDEEDAYQVIKAFDFEFFKLEDVLKKAGDVLADLTECTAITLDVEPSNQRLSAFDIVKLSHHDALAVMTFDDSNTVTSQFAIPKNFLDEDLLVVSQLVRERFLGQTVMEIHYRIRTEIPQIVQRYFKITDNVLELFEHIFKEMFVEKLFLSGKENLLKYSDDQTYRLLDNTQELALTIRRQFQEEQAYVIRLADENKQGLEALSQLSYKFLIPYRGFGNLTLLGPVTIDYRRSMGLLNVVSRVLTMKLADFYRYLSSNHYEVH
>CP029490.1|AWN20013.1|167508_168093_+|N-acetyl-muramidase
MQSRLKFRPFMIVFGLVLALVLLPLLLNMRTKAANTKVTSTYSQASFIKEVAPVAQKLSKAYGVKASVLIAQVAQSTDYGSNLLAVRYHNYLGVLAQPGDARIVLTTQSYEKGKWETVKQPYKIYENWQDSLYDYMEEISAGMWGKQLYTTLATTEEYTTAARALQKAGVDTDPEYANKLIAIIQGKNLTQYDK
>CP029490.1|AWN20012.1|166576_167344_+|D-alanyl-D-alanine-carboxypeptidase-family-protein
MNKRSRQFLMIFFAVLVIIFGFAYFHDRKASQQSKGTSSQTTKTKQVTRAAGSSSDNNSSASGSDLPDVSADDWQLIVVNRDNITKELNPDLTTIDNIKVDSRIADNVKEFLAAAQKIDSKEHLISGYRSVAYQKELFDSYVKQEMSNDPSLSESQAEDKVKTYSQPAGASEHQTGLAIDMSTVDSLNESDPTVVEQLKKIAPDYGFVLRFEQGKSDSTGVDYEDWHFRYVGKASAKYMTEHNLSLEEYVAQLKK
>CP029490.1|AWN20011.1|165888_166590_+|histidine-phosphatase-family-protein
MAKTRLFIARHGKTMFNTIGRAQGWSDTPLTKEGERGIQELGLGLKEAGLHFVAAYSSDSGRTLQTMEIILRELGQETIPYKRDKRIREWCFGSLDGGYDAELFNGVIPRVFDKPVEEMTYQDMANAIMAVDTAGWAEPWEALKNRIITGFSDIAKEVQAKGGGDAIVVSHGMTIATLIGLIDPSQPRSLALDNGSICQLTYEDGDLHIEAIGDMSYRQKGREILEKEANEQA
>CP029490.1|AWN20010.1|165318_165750_-|MarR-family-transcriptional-regulator
MDLNQSLGFLLNSGAKLMKRQLDSKLRAYQITSSQWAVLKLLSQNDKLSQVEIAQAIKTDKATCGAIIDKLIKKEFVKRTISQQDQRARIIEISPLALSVTDELTSLDEETNTEALMGIKQKEQEIFIKTLEQLIINLENKEI
>CP029490.1|AWN20009.1|164192_165128_-|IS30-family-transposase
MSYSHLTITDRIKIETYLELGLKPCQIANKLGVHKSTISRELRRCQNGYSAALAQEQYDHRAKQKGRKSRLTPKLKKEIEDGLKSSWSPEQICGRYQLEQKPMVAFKTIYNWLYAALIDLDLSVLRRKGKTRQPKETRGTFRIGTSIAKRPKEVRNRETFGHWELDTVVSSRGKSKGCLATFLERKTRFYLAFKIPDRTAKSMFSAIEQLCKLFPKEALKTFTSDRGKEFACYPLVENLGISFFFADAYSSWQRGSNENANGLLREYFPKKTDLAAISDEVLNKALYDINHRPRKCLAYRTASEALEDEFK
>CP029490.1|AWN20008.1|162287_163625_+|PFL-family-protein
MDIQQVTETIAMIEEQNFDVRTITMGISLLDCIDPDINRAADKVYRKIVDKAANLVAVGDEISAELGIPIVNKRVSVTPISIIGAATDATDYVPLAKAMDKAAKEIGINFIGGFSALVQKGYQKGDEILIESIPRALAETDFVCSSVNIGSTKSGINMTAVRDMGQIIKETAQLSEMGPAKLVVFANAVEDNPFMAGAFHGVGEADVVINVGVSGPGVVKRALEKVKGQSFDVVAETVKKTAFKITRIGQLVGSLASERLGVKFGIVDLSLAPTPAVGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDEGMIAAVEAGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKTTAVRLIPRGREGDTIEFGGLLGSAPVMSVNKNSSADFIARGGQIPAPIHSFKN
>CP029490.1|AWN20007.1|162009_162276_+|ACT-domain-containing-protein
MKAIITVVGKDSQGIVAGVSAKIADLRLNIDDITQTILDEYFTMMAVVSSPEKKDFSLLRLELEKLGEQLGVKINIQSSAIFDAMHKL
>CP029490.1|AWN20016.1|172523_173660_+|molecular-chaperone-DnaJ
MNNQEYYDRLGVSKDASQDEIKKAYRKMSKKYHPDINKEPGAEEKYKDIQEAYETLGDEQKRAAYDQYGPDGANFGGGGAGGFSGFDGAGFGGFEDIFSSFFGGGGASRNPSAPRQGDDLQYRLNLEFEEAIFGADKDVTYNREAECETCHGSGAKPGTSPITCSRCHGQGVINVDTQTPLGMMRRQVTCDVCHGTGKEIKEPCDTCHGTGHEKKAHKVSVKVPAGVETGQQIRLSGQGEAGFNGGPYGDLFVIINVLPSKKFERDGSTIYYTLNISFAQAALGDTVEVPTVHGYVEMTIPEGTQTGKTFRLKGKGAPRLRGGSQGDQHVTINVVTPTKLNEAQKEALLALAAASGETSIRPKKKGFFDKVKDAFDGE
>CP029490.1|AWN20017.1|174059_174833_+|tRNA-pseudouridine(38-40)-synthase-TruA
MVRYKAVISYDGTLFAGFQHQTKERSVQEELEKTLERLNSGQPVKVHGAGRTDSGVHAYGQVIHFDLPQARDEEKLRFGLDTQSPEDIDVVSIQQVPDDFHARYNPHSKTYEFLVDTGRPKNPMMRAYATHFPYTVDLAAMQDAIADLIGTHDFTGFTASGTSVQNKVRTITEAKVERDPKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRMPVGQVKTILAAKDRNLAGPTAAGNGLYLKEITYESKNSSDFRQ
>CP029490.1|AWN20018.1|174798_175560_+|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase
MSQKILAISGNDVFSGGGLYADLTTYTLNGLRGFLAVTCLTAMTEQGFQVFATDAKVFRAQLASLQKVDFAGVKLGLLPNVEVAEAALNFVRSRKDLPIVLDPVLVCKEKHDVAVSALRDELLQFLPYVSILTPNLAEAEILTGLSIKNLEDMKQAAQKLQAMGAKAVVVKGGNRLDSDQALDVYCDEKGLEVLSGPLSDKNNVGAGCTFASSIASQLVLGKEPLEAVKLAKEFVYQAILHSDDYGVVQAYDK
>CP029490.1|AWN20019.1|175549_176020_+|ECF-transporter-S-component
MTSKKTRELTLLAILTALSLALGFIHIPSPTGFLTLIDTGIFFTAFYLGSKSGAVVGGLSAFLLDFLLAYPQYMFFSLFAHGLQGYFAGWTGVRRYLGLLLASLAMVGIYILAALVLGFGWGAALAGIWGNLSQNVLGLVVGAALYRAFSKAFPRK
>CP029490.1|AWN20020.1|176028_176592_+|TIGR01440-family-protein
MDLQNLEKETRAIVRDILERSAIKQGQIFVLGLSSSEVAGGRIGQNSSLEIGQVIVKTILEETKLKGVHLAVQGCEHLNRALVVEEAVAESKGLEIVNVLPGLHAGGSGQLAALDYMENPVEVEAVVAHAGLDIGDTFIGMHVKRVQVPLIPLQRELGGAHVTALASRPKLIGGARAKYKADPIRKN
>CP029490.1|AWN20021.1|176740_177589_-|mechanosensitive-ion-channel-family-protein
MSIFIKYWESLHFEDLAVNLLAKAIELALLVFAFIIGKQIANWAFDKFFSHSPRLLGQTEGRRKTLIKLFHNVMNYFLYFLLIYWILAILGLPVSSLLAGAGIAGLAIGLGAQGFLSDLVNGFFILIERQFDVGDSVTVDQVSGIVSSVGIRTTEIRDFDGTLHFIPNREILLVSNKSRGDMRAQIDIPIYASTNLDRVTQIIKEVNEIEVPNSPEIVGVPNVLGPRTASNGQFIFRVDIFVQNGQQAEIYSKFYRLYQEALLKDDISLPTPNTHIQPSQKS
>CP029490.1|AWN20022.1|177831_179115_+|trigger-factor
MSVSFENTATNRGVLTFTISQEQIQPALDTAFNKVKKNLNVPGFRKGHMPRAVFNQKFGEEALYEDALNAILPTAYEAAVAESGLDVVAQPKIDVDSMEKGQDWSIKAEVVTKPEVKLGDYKNLEVSVEESKEVSDQDVNDKIERERKNLAELTIKDAAAENGDTVVIDFVGTVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDDVEVKVTFPADYQAEDLAGKDAVFATKVHEVKSKEVPELDDELAKDIDEEVETLDELKAKYRKELEAAKEIAYDDAVEGAAIEKAVENAEIVELPEEMVHDEVHRAMNEFLSNMQRQGISPEMYYQLTGTTEEDLHKQYEADADKRVRTNLVIEAIAAAEGFDATDEEIEKEITDLAAEYNMPADQVRSLLSADMLKHDITMKKAIEAITSSAKVK
>CP029490.1|AWN20023.1|179308_179947_+|haloacid-dehalogenase
MGLLVDTEYLDFQLQSGYLRSIASPSVTLGVKDFSSLVGRSGQDLLMQVRNLTQTEKTFAEITAGLKKIEAKKYHPDNYLPLFRQDIVPLLQYAKEQRLLLAVASSTALNYLLDILDNCGIRNYFDLIVSGEDFESSKPHPEIYLSVLKALHVAPEEAIAIEDSSAGIAAAKAAGMDVIAYEEKRFLIDQTQANLICKNMRAIFCHIKSLRK
>CP029490.1|AWN20024.1|180037_180619_+|DNA-directed-RNA-polymerase-subunit-delta
MELKVFAGQEKSELSMIEVARAILESRGRDHEMYFSDLVNEIQNYLEKSDADIRQALPFFYSDLNTDGSFIPLGENRWGLRTWYAIDEIDEEVITLEENGENAPKRKRKRVNAFMDGDEDAIDYNDDDPEDEDNFTPTDVEYDDENPDDEKSEVESYDSEINEIIPDEEVSDDEDDVDLNESDDEDDDEAEND
>CP029490.1|AWN20025.1|180911_182516_+|CTP-synthase
MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKERKGEYLGATVQVIPHITDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQMKADVGSDNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEQPATQGVKNKLAQFCDVAPEAVIESLDVDHIYQVPLNMQAQGMDQIVCDHLKLDVPKADMTEWSAMVDRVLNLKKSTRIALVGKYVELPDAYLSVVEALKHSGYVNDSAIDLKWVNANDVTAENVADLLGDVDGIIVPGGFGHRGTEGKIQTIRYARENDVPMLGICLGMQLTCVEFARHVLNMQGANSSELDPDTSYPVIDLMRDQVDVEDMGGTLRLGLYPCKLKPGSKAAAAYNNQEVVQRRHRHRYEFNTKYREVFEAAGFVFSGVSPDNRLMEVVELPDKKFFVAAQYHPELQSRPNRAEELYTAFVTAAVENAK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP029490_1	1.1\|171984\|25\|CP029490\|CRISPRCasFinder	171984-172008	25	MH648987	Siphoviridae sp. isolate ctcj11, complete genome	23844-23868	3	0.88

1. spacer 1.1|171984|25|CP029490|CRISPRCasFinder matches to MH648987 (Siphoviridae sp. isolate ctcj11, complete genome) position: , mismatch: 3, identity: 0.88

gagcttgaaaactgggaagcgaggc	CRISPR spacer
gagcttgataactgggaagcgatac	Protospacer
******** ************* .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

476841 : 530984

Streptococcus_phage(62.5%)

protease,transposase,bacteriocin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWN20274.1\|476841_477777_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	8.1e-87	54.3
AWN20275.1\|478256_480359_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	1.5e-117	37.7
AWN20276.1\|480792_481638_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
AWN20277.1\|481870_482245_-	PTS-dependent dihydroxyacetone kinase phosphotransferase subunit DhaM	NA	NA	NA	NA
AWN20278.1\|482245_482824_-	dihydroxyacetone kinase subunit L	NA	NA	NA	NA
AWN20279.1\|482862_483840_-	dihydroxyacetone kinase subunit DhaK	NA	NA	NA	NA
AWN20280.1\|484268_484988_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
AWN20281.1\|486611_487709_+	ArsR family transcriptional regulator	NA	NA	NA	NA
AWN20282.1\|487727_488315_+	transcriptional regulator	NA	NA	NA	NA
AWN20283.1\|488461_489121_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	1.0e-72	63.9
AWN20284.1\|489249_489903_+	dTMP kinase	M1PSC7	Streptococcus_phage	9.1e-69	64.3
AWN20285.1\|489905_490769_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	3.5e-76	53.8
AWN20286.1\|490765_491566_+	signal peptidase II	NA	NA	NA	NA
AWN20287.1\|491558_491879_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	7.9e-26	55.7
AWN20288.1\|491882_492749_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	2.0e-116	73.6
AWN20289.1\|492969_494205_+	ammonium transporter	NA	NA	NA	NA
AWN20290.1\|494272_494614_+	P-II family nitrogen regulator	NA	NA	NA	NA
AWN20291.1\|494835_497517_+	aconitate hydratase AcnA	NA	NA	NA	NA
AWN20292.1\|497558_498677_+	citrate synthase	NA	NA	NA	NA
AWN20293.1\|498681_499863_+	NADP-dependent isocitrate dehydrogenase	NA	NA	NA	NA
AWN20294.1\|501949_503044_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.8e-165	79.1
AWN20295.1\|503083_503632_+	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	1.2e-58	59.9
AWN20296.1\|504179_505358_+	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	8.5e-174	77.4
AWN20297.1\|505434_505665_+	hypothetical protein	NA	NA	NA	NA
AWN20298.1\|505661_506156_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	2.4e-45	55.4
AWN20299.1\|506170_506527_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	9.4e-36	60.7
AWN20300.1\|506609_508382_-	MFS transporter	NA	NA	NA	NA
AWN20301.1\|508575_509127_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AWN20302.1\|509518_510382_+	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
AWN20303.1\|510795_510966_+\|bacteriocin	thiazolylpeptide-type bacteriocin	NA	NA	NA	NA
AWN20304.1\|511044_511980_+	hypothetical protein	NA	NA	NA	NA
AWN20305.1\|511960_512620_+	hypothetical protein	NA	NA	NA	NA
AWN20306.1\|512622_514299_+	hypothetical protein	NA	NA	NA	NA
AWN20307.1\|514315_515164_+	hypothetical protein	NA	NA	NA	NA
AWN20308.1\|515274_516210_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	8.1e-87	54.3
AWN20309.1\|516196_517021_+	hypothetical protein	NA	NA	NA	NA
AWN20310.1\|517021_517774_+	hypothetical protein	NA	NA	NA	NA
AWN20311.1\|517786_518866_+	N-acyl-L-amino acid amidohydrolase	NA	NA	NA	NA
AWN20312.1\|518865_521235_+	lanthionine biosynthesis protein	NA	NA	NA	NA
AWN20313.1\|521313_521988_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.4e-18	29.8
AWN20314.1\|521989_522709_+	ABC transporter	NA	NA	NA	NA
AWN20315.1\|523269_523767_+	peptidase, C39 family protein	NA	NA	NA	NA
AWN20316.1\|525129_525324_+	hypothetical protein	NA	NA	NA	NA
AWN20317.1\|525750_526152_+	thioredoxin	NA	NA	NA	NA
AWN20318.1\|526273_526645_+	thioredoxin	NA	NA	NA	NA
AWN20319.1\|526947_528279_+	lipase	NA	NA	NA	NA
AWN20320.1\|528359_529927_-\|transposase	IS3 family transposase	A0A0C5AC89	Paenibacillus_phage	2.3e-54	49.6
AWN20321.1\|530048_530984_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	8.1e-87	54.3

DBSCAN-SWA_2

966125 : 985556

Lactococcus_phage(33.33%)

transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWN20675.1\|966125_966344_+\|bacteriocin	ComC/BlpC family peptide pheromone/bacteriocin	NA	NA	NA	NA
AWN20676.1\|966993_967422_+	hypothetical protein	NA	NA	NA	NA
AWN20677.1\|967491_967635_+\|bacteriocin	bacteriocin-type signal sequence	NA	NA	NA	NA
AWN20678.1\|967660_968065_+	hypothetical protein	NA	NA	NA	NA
AWN20679.1\|968114_969149_+	thiol reductase thioredoxin	NA	NA	NA	NA
AWN20680.1\|969430_969856_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	3.4e-16	35.2
AWN21773.1\|970261_970615_+	immunity protein	NA	NA	NA	NA
AWN20681.1\|970711_971152_+	hypothetical protein	NA	NA	NA	NA
AWN21774.1\|971307_971565_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
AWN20682.1\|971600_971897_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
AWN20683.1\|972455_972920_+	hypothetical protein	NA	NA	NA	NA
AWN20684.1\|973340_974492_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
AWN20685.1\|974497_975202_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.3e-32	38.9
AWN20686.1\|975214_976456_+	hypothetical protein	NA	NA	NA	NA
AWN20687.1\|976934_978155_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
AWN20688.1\|978138_978984_+	alpha/beta hydrolase	NA	NA	NA	NA
AWN20689.1\|979048_979861_+	KR domain-containing protein	NA	NA	NA	NA
AWN20690.1\|980206_980554_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
AWN20691.1\|980652_980964_+	transcriptional regulator	NA	NA	NA	NA
AWN20692.1\|981129_981402_+	30S ribosomal protein S16	NA	NA	NA	NA
AWN20693.1\|981413_981653_+	KH domain-containing protein	NA	NA	NA	NA
AWN20694.1\|982241_982886_+	transcriptional regulator	NA	NA	NA	NA
AWN20695.1\|982882_983416_+	PadR family transcriptional regulator	NA	NA	NA	NA
AWN20696.1\|983447_984425_+	DUF4872 domain-containing protein	NA	NA	NA	NA
AWN20697.1\|984620_985556_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	8.1e-87	54.3

DBSCAN-SWA_3

1265116 : 1272512

Streptococcus_phage(50.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWN20956.1\|1265116_1265794_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	1.3e-89	69.3
AWN21784.1\|1265801_1266962_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	2.6e-151	68.8
AWN20957.1\|1267079_1269233_+	LTA synthase family protein	W6LM83	Streptococcus_phage	9.4e-264	68.5
AWN20958.1\|1269497_1270115_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AWN20959.1\|1270283_1270598_-	phosphoribosyl-ATP diphosphatase	NA	NA	NA	NA
AWN20960.1\|1270714_1271035_-	phosphoribosyl-AMP cyclohydrolase	A0A2H4UVM0	Bodo_saltans_virus	2.6e-08	30.8
AWN20961.1\|1271031_1271790_-	imidazole glycerol phosphate synthase subunit HisF	A0A2H4UVM0	Bodo_saltans_virus	2.8e-05	24.7
AWN20962.1\|1271792_1272512_-	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase	A0A2H4UVM0	Bodo_saltans_virus	2.8e-10	24.8

DBSCAN-SWA_4

1873964 : 1924632

Staphylococcus_phage(36.36%)

tRNA,transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWN21482.1\|1873964_1874900_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	6.2e-10	38.1
AWN21483.1\|1875201_1877586_-	primosomal protein N'	NA	NA	NA	NA
AWN21484.1\|1878371_1878689_-	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
AWN21485.1\|1878711_1879326_-	guanylate kinase	NA	NA	NA	NA
AWN21486.1\|1879536_1880481_+	magnesium transporter CorA family protein	NA	NA	NA	NA
AWN21487.1\|1880510_1881200_+	DUF1129 domain-containing protein	NA	NA	NA	NA
AWN21488.1\|1881629_1881869_-	30S ribosomal protein S18	NA	NA	NA	NA
AWN21489.1\|1881926_1882409_-	single-stranded DNA-binding protein	A0A191KBQ2	Streptococcus_virus	7.4e-60	73.9
AWN21490.1\|1882420_1882711_-	30S ribosomal protein S6	NA	NA	NA	NA
AWN21491.1\|1883165_1883837_-	DUF1211 domain-containing protein	NA	NA	NA	NA
AWN21492.1\|1884639_1884813_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
AWN21493.1\|1884832_1885018_-	hypothetical protein	NA	NA	NA	NA
AWN21494.1\|1885100_1885274_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
AWN21495.1\|1885295_1885481_-	hypothetical protein	NA	NA	NA	NA
AWN21496.1\|1885774_1885966_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
AWN21497.1\|1886267_1886492_-\|bacteriocin	ComC/BlpC family peptide pheromone/bacteriocin	NA	NA	NA	NA
AWN21498.1\|1887862_1888786_-	HlyD family secretion protein	NA	NA	NA	NA
AWN21499.1\|1888800_1891107_-	peptide ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	6.8e-42	27.7
AWN21500.1\|1892887_1894009_+	A/G-specific adenine glycosylase	NA	NA	NA	NA
AWN21501.1\|1894280_1894709_+	DUF2992 domain-containing protein	NA	NA	NA	NA
AWN21805.1\|1895180_1896224_-	Zn-dependent alcohol dehydrogenase	NA	NA	NA	NA
AWN21502.1\|1896423_1896738_-	thioredoxin	A0A1J0GW78	Streptomyces_phage	6.0e-18	47.3
AWN21503.1\|1897042_1897246_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
AWN21504.1\|1897286_1898183_-	cation transporter	NA	NA	NA	NA
AWN21505.1\|1898209_1900447_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	2.1e-96	34.0
AWN21506.1\|1900447_1900894_-	CopY/TcrY family copper transport repressor	NA	NA	NA	NA
AWN21507.1\|1901041_1901740_-	hypothetical protein	NA	NA	NA	NA
AWN21508.1\|1901723_1902407_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.3e-21	31.8
AWN21509.1\|1903182_1903536_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
AWN21510.1\|1904152_1906870_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	2.8e-18	24.9
AWN21511.1\|1906888_1907191_-	hypothetical protein	NA	NA	NA	NA
AWN21512.1\|1907183_1907480_-	DUF448 domain-containing protein	NA	NA	NA	NA
AWN21513.1\|1907494_1908811_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
AWN21514.1\|1908992_1909469_-	ribosome maturation factor RimP	NA	NA	NA	NA
AWN21515.1\|1909939_1911541_-	hypothetical protein	NA	NA	NA	NA
AWN21516.1\|1912325_1912961_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
AWN21806.1\|1912961_1913753_-	aminoglycoside phosphotransferase	NA	NA	NA	NA
AWN21517.1\|1914098_1915145_-	multidrug ABC transporter permease	NA	NA	NA	NA
AWN21518.1\|1915147_1915873_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.3e-27	30.7
AWN21519.1\|1916150_1916570_+	HIT family protein	NA	NA	NA	NA
AWN21520.1\|1916566_1916857_+	hypothetical protein	NA	NA	NA	NA
AWN21521.1\|1917043_1918279_-	LytR family transcriptional regulator	NA	NA	NA	NA
AWN21522.1\|1918287_1918800_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AWN21523.1\|1918792_1919233_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
AWN21524.1\|1919406_1920825_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	2.9e-43	31.9
AWN21525.1\|1921916_1922852_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	8.1e-87	54.3
AWN21807.1\|1923331_1923601_-	YSIRK-type signal peptide-containing protein	NA	NA	NA	NA
AWN21526.1\|1923696_1924632_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	8.1e-87	54.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage