CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP028468	Staphylococcus aureus strain IT1-S chromosome, complete genome	9 crisprs	cas3,DEDDh,RT,DinG,csa3,WYL	5	0	11	0
CP028469	Staphylococcus aureus strain IT1-S plasmid pIT1-S, complete sequence	0 crisprs	csa3	0	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP028468_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028468_1

261358-261495

Orphan

Consensus_repeat	Method
TGCAAGTTGGCGGGGCCCCAACATAGA	CRISPRCasFinder

2 spacers

The CRISPR arrays of CP028468_1

>merge|CP028468|1|261358-261495|CRISPRCasFinder
TGCAAGTTGGCGGGGCCCCAACATAGAGAATTTCGAAAAGAAATTCTACAGGCAATGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGGGGAGGGACATAAATAAA

>CP028468|1|1|261358-261495|CRISPRCasFinder
TGCAAGTTGGCGGGGCCCCAACATAGA	GAATTTCGAAAAGAAATTCTACAGGCAA
TGCAAGTTGGCGGGGCCCCAACATAGA	AGCTGGCGGAAAGTCAGCTTACAATAATG
TGCAAGTTGGGGAGGGACATAAATAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP028468.1\|AWQ21837.1\|255622_257914_+\|nitric-oxide-reductase-large-subunit	unknown	unknown	gnl\|CDD\|225795
CP028468.1\|AWQ21839.1\|258992_259784_+\|PTS-glucose-transporter-subunit-IIABC	unknown	unknown	gnl\|CDD\|225101
CP028468.1\|AWQ21850.1\|271042_271702_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
CP028468.1\|AWQ21834.1\|253291_254032_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|184495
CP028468.1\|AWQ21845.1\|265216_266215_-\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
CP028468.1\|AWQ21838.1\|258139_258844_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
CP028468.1\|AWQ21848.1\|268725_269718_+\|linear-amide-C-N-hydrolase	unknown	unknown	gnl\|CDD\|225591
CP028468.1\|AWQ21844.1\|264103_264985_-\|ribose-transporter-RbsU	unknown	unknown	gnl\|CDD\|284268
CP028468.1\|AWQ21841.1\|261730_262492_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
CP028468.1\|AWQ21849.1\|270043_270991_+\|glycine-glycine-endopeptidase-LytM	unknown	unknown	gnl\|CDD\|226451
CP028468.1\|AWQ21831.1\|248749_250471_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|376098
CP028468.1\|AWQ21842.1\|262742_263657_-\|ribokinase	unknown	unknown	gnl\|CDD\|274000
CP028468.1\|AWQ21832.1\|250614_251289_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	unknown	unknown	gnl\|CDD\|183940
CP028468.1\|AWQ21836.1\|254580_255282_+\|antiholin-like-protein-LrgB	unknown	unknown	gnl\|CDD\|179810
CP028468.1\|AWQ21846.1\|266595_266988_+\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ21833.1\|251549_253289_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225814
CP028468.1\|AWQ21843.1\|263684_264089_-\|D-ribose-pyranase	unknown	unknown	gnl\|CDD\|183318
CP028468.1\|AWQ21847.1\|267115_268492_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
CP028468.1\|AWQ21840.1\|259799_261236_+\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|181973
CP028468.1\|AWQ21835.1\|254144_254588_+\|antiholin-like-murein-hydrolase-modulator-LrgA	unknown	unknown	gnl\|CDD\|235222

Protein	Function_ID	Function_description	E-value
CP028468.1\|AWQ21837.1\|255622_257914_+\|nitric-oxide-reductase-large-subunit	gnl\|CDD\|225795	COG3256, NorB, Nitric oxide reductase large subunit [Inorganic ion transport and metabolism].	5.48419e-178
CP028468.1\|AWQ21839.1\|258992_259784_+\|PTS-glucose-transporter-subunit-IIABC	gnl\|CDD\|225101	COG2190, NagE, Phosphotransferase system IIA components [Carbohydrate transport and metabolism].	8.99936e-55
CP028468.1\|AWQ21850.1\|271042_271702_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	9.68709e-67
CP028468.1\|AWQ21834.1\|253291_254032_+\|DNA-binding-response-regulator	gnl\|CDD\|184495	PRK14084, PRK14084, DNA-binding response regulator.	4.37999e-152
CP028468.1\|AWQ21845.1\|265216_266215_-\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	4.32136e-100
CP028468.1\|AWQ21838.1\|258139_258844_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.13754e-62
CP028468.1\|AWQ21848.1\|268725_269718_+\|linear-amide-C-N-hydrolase	gnl\|CDD\|225591	COG3049, COG3049, Penicillin V acylase and related amidases [Cell envelope biogenesis, outer membrane].	6.16271e-152
CP028468.1\|AWQ21844.1\|264103_264985_-\|ribose-transporter-RbsU	gnl\|CDD\|284268	pfam06800, Sugar_transport, Sugar transport protein. This is a family of bacterial sugar transporters approximately 300 residues long. Members include glucose uptake proteins, ribose transport proteins, and several putative and hypothetical membrane proteins probably involved in sugar transport across bacterial membranes. These members are transmembrane proteins which are usually 5+5 duplications. This model recognizes a set of five TMs,.	2.15665e-116
CP028468.1\|AWQ21841.1\|261730_262492_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.23141e-27
CP028468.1\|AWQ21849.1\|270043_270991_+\|glycine-glycine-endopeptidase-LytM	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.47013e-32
CP028468.1\|AWQ21831.1\|248749_250471_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|376098	pfam18674, TarS_C1, TarS beta-glycosyltransferase C-terminal domain 1. Beta-glycosyltransferase TarS is an enzyme responsible for the glycosylation of wall teichoic acid polymers of the S. aureus cell wall, a process that has been shown to be specifically responsible for methicillin resistance in MRSA. It contains a trimerization domain composed of tandem carbohydrate binding motifs.The two C-terminally localized regions composed of a series of beta-sheets participate in an extensive trimerization interface and they assume an immunoglobulin-like fold. It is suggested that both carbohydrate binding domains may be involved in polyRboP binding, however unlike pullulanase, the CBMs of TarS are involved in the formation of an extensive trimerization interface.	3.18504e-35
CP028468.1\|AWQ21842.1\|262742_263657_-\|ribokinase	gnl\|CDD\|274000	TIGR02152, Putative_ribokinase, ribokinase. This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars].	7.32816e-143
CP028468.1\|AWQ21832.1\|250614_251289_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	gnl\|CDD\|183940	PRK13276, PRK13276, iron-sulfur cluster repair di-iron protein ScdA.	1.30038e-153
CP028468.1\|AWQ21836.1\|254580_255282_+\|antiholin-like-protein-LrgB	gnl\|CDD\|179810	PRK04288, PRK04288, antiholin-like protein LrgB; Provisional.	5.86643e-124
CP028468.1\|AWQ21833.1\|251549_253289_+\|sensor-histidine-kinase	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	0
CP028468.1\|AWQ21843.1\|263684_264089_-\|D-ribose-pyranase	gnl\|CDD\|183318	PRK11797, PRK11797, D-ribose pyranase; Provisional.	4.08879e-70
CP028468.1\|AWQ21847.1\|267115_268492_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.58117e-30
CP028468.1\|AWQ21840.1\|259799_261236_+\|6-phospho-beta-glucosidase	gnl\|CDD\|181973	PRK09589, celA, 6-phospho-beta-glucosidase; Reviewed.	0
CP028468.1\|AWQ21835.1\|254144_254588_+\|antiholin-like-murein-hydrolase-modulator-LrgA	gnl\|CDD\|235222	PRK04125, PRK04125, antiholin-like protein LrgA.	8.44339e-64

>CP028468.1|AWQ21840.1|259799_261236_+|6-phospho-beta-glucosidase
MTKLPQNFMWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKARQITESIDPNHYYPNHEGIDFYHRYKEDIALFKEMGLKCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDFGWQEGDDSILQQGTVDYIGFSYYMSTAVKHDVDTTVENNIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYLKVHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYKQVIASNGDKL
>CP028468.1|AWQ21839.1|258992_259784_+|PTS-glucose-transporter-subunit-IIABC
MSNKYKDQAQDILTAVGGVENIVDVTYDTKGITIHMQHTIPSTANEVKQIVDVTSVAENDAQLVIKLNGNVDEVYQQLQRLIKDANVEEGANTDNINSQDTSYTPQAKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGLISMIVPTKHAIGIRSEEGVDIVIHIGVNTVDLEGKGFKCFVKQNDRVEAGQTLLQFDQQYIQEQGYNSDVIVVISNSADLGKVELTMNEIITTEDVIFKIFKN
>CP028468.1|AWQ21838.1|258139_258844_-|GntR-family-transcriptional-regulator
MLKYEHIAKQLNAFIHHSNFKPGDKLPSVTQLKERYQVSKSTIIKALGLLEQDGLIYQAQGSGIYVRNIADANRINVFKTNGFSKSLGEHRMTSKVLVFKEIATPPKSVQDELQLNADDTVYYLERLRFVDDDVLCIEYSYYHKEIVKYLNDDIAKGSIFDYLESNMKLRIGFSDIFFNVDQLNSSEAALLQLSKGEPCLRYHQTFYTMTGKPFDSSDIVFHYRHAQFYIPSKK
>CP028468.1|AWQ21837.1|255622_257914_+|nitric-oxide-reductase-large-subunit
MSMQSSYKRLVKVLLTILVIVFSILLVGGWYIFKNEAPRPTKIVDQQGHTLVTKGELISGQAIYEKYGLTDYGSYLGNGSYLGPDYTAEALHHYLIGMRKYYAQDIYHKQLHKLNHAELAVVKDKVMKEIRINRYSEKEDQLVLTPGQVYGLKYLQDYYKKEFVNNPKQVGLNENMIKQFQNDDYMVAGNKVEHLSQFFFWGAWLSSTDRPGKTFSYTNNWPYDVDAGNTLPSAGILWTAISVTLLIAGLAFIIYIQKRYQFDMKPTYESERELPKIEVDRKITDSQRKVGKYLVVVMLLFLVQILLGELLAHYYVENKFFGIEIQRLFPFNIAKTWHVQLVIFWVATTWLAAGIYIVPKVLGKEPKKQGVLVDILFWALIIVVMGSMIGEWGHILGWIDSHWWLFGHFGWEYIELGKFWQILFIVGMVLWVIILCRGFLPAIRNKVQVNHDKRHLLTLLFVGAIAIPLFYLASLFIMPNSHVTFADYWRWWIVHLWVEGIFEAFAVVLIGFLMVNMKLTTIETTIRALYFQLILLLGTGIVGMGHHYYWQGDHSIWLALGSCFSALEVVPLCLLIWEAYTHYRLYKNSDIAFPYKGTFIFLASTGLWNAIGAGALGFLINTPAVNYFEHGTQWTAAHAHGSMAGVYGMFSIAIALYVFKNITKKEFWTPKVEKWIKISCWALNIGLAGMVFVTLMPVGYIQLKDALEHGYWHSRLTSFYEQPLVKAIMWGRMPWDIIFTVGVIILVVIFIRGYRHLKPKYRV
>CP028468.1|AWQ21836.1|254580_255282_+|antiholin-like-protein-LrgB
MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
>CP028468.1|AWQ21835.1|254144_254588_+|antiholin-like-murein-hydrolase-modulator-LrgA
MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
>CP028468.1|AWQ21834.1|253291_254032_+|DNA-binding-response-regulator
MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNSASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPAYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
>CP028468.1|AWQ21833.1|251549_253289_+|sensor-histidine-kinase
MLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
>CP028468.1|AWQ21832.1|250614_251289_+|iron-sulfur-cluster-repair-di-iron-protein-ScdA
MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAAVLEKKNVDLNELLQRLNEVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKATYDTFKNGMLEHMQKEDDVDFPKLIKYEQGEVVDDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
>CP028468.1|AWQ21831.1|248749_250471_+|glycosyltransferase-family-2-protein
MMKFSVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTALLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEDQPQWINALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGKLNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHSRNKKHTMYVPLTVNANKQYRFNIMLEDIKADLPKEKIWDVFLEVQIGTEVFEVRVGNQRNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISMKLKGKNKIILTGLDRGYVFEEGMASVVLKDDMVMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTAHMTYSLK
>CP028468.1|AWQ21841.1|261730_262492_-|class-I-SAM-dependent-methyltransferase
MSKEAGHTFLAKLGKTRLRPGGKEATDWLIQQGAFSQDKQVLEVACNMCTTSIYLAHTYGCHIQGVDINKKALEKAQENISAAGLESYIQVQQANAVKLPFDDNQFDIVLNEAMLTMLPIAIKEKALREYYRVLKPGGILLTHDIVIVNESHATHVVKSLSAAINVNVSPQTKLGWLDLYHQAGFNHVHYHTGPMSLMTPKGLIYDEGIVGTLKIINNALKKENRPMFCKMFKTMTKLRKDMNYITFVAKKEH
>CP028468.1|AWQ21842.1|262742_263657_-|ribokinase
MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIGTDGVADFILEDFKAAHIDTSYIIKTAEAKTGQAFITVNAEGQNTIYVYGGANMTMTPEDVINAKDAIINADFVVAQLEVPIPAIISAFEIAKSHGVTTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSLGIKTVLITLGKQGTYFATKNQSQHIEAYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEEVNQV
>CP028468.1|AWQ21843.1|263684_264089_-|D-ribose-pyranase
MKKTAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
>CP028468.1|AWQ21844.1|264103_264985_-|ribose-transporter-RbsU
MSIVALLIGLGPLIGWGFFPTVASKFGGKPVHQIIGATVGTLIFAIILAVVTSSGFPTGTNLLFALLSGAGWGFGQIITFKAFELVGSSRAMPVTTAFQLLGASLWGVFALGNWPGIGHKIIGFTALVVILIGARMTVWSERKEASNAKNLRRAVVLLLIGEFGYWLYSAAPQATSIDGLTAFLPQAMGMVIVAVIYGFMNMKAENPFRNKITWLQIISGFFFAFGALTYLISAQPNMNGLATGFILSQTSVVLATLTGIYFLKQHKTSKEMVITIIGLVLILVATSVTVFIK
>CP028468.1|AWQ21845.1|265216_266215_-|LacI-family-transcriptional-regulator
MKKVSIKDVAREAGVSVTTVSHILNHNDSRFSATTIKNVHAVSERLGYAPNKHAKQLRGSKIQTIGVILPSLTNPFFSALMQSIHDHKPSDVDLCFLTSTATDLYDNIKHLIDRGIDGLIIAQYISSPDALNNYLKKHHVPYVVLDQNDHQGYTDFVRTNEYQGGQLAAQHLIELGHNNMIVVAPYDMMANMSTRVAGFVDTLRANQLPEPQIVHTELSKRGGLTIVDDIMVQSATAIFAINDELAIGILRGLIEHGISIPKDISLIGYDDIDYAAYVSPPLTTVAQPITDIGKTSLTLLLQRLQHLDKSIDMIELPTTLKIRATTGYHLSN
>CP028468.1|AWQ21846.1|266595_266988_+|hypothetical-protein
MQFKLKEEEIISFLELKYPEKEFEYGRLLVGQHKRDDLDVYYFGDTFLMCTIISFKTFEIKETVELSYDAVNRIVLKDGWLFRKMRIETMQKVLKYGTSKLMLTDFQKENYNKYIQGQKQRVIFENGHFV
>CP028468.1|AWQ21847.1|267115_268492_-|MFS-transporter
MNNTQSSPRSNIIIAIMLSALTYWLFAQSFINIGPLVGQTYQTSPAVLNLSISLTSFATGIFMVAAGDIADKIGQLRMTYMGLIISMFASLLLIISDITALLIIGRILQGLSAAILLPSTVGVLNNQFKGEHLRRAISYLMISTVGGIGLAGVIGGLIATNFGWQTNFIISIVIAFIAILLLKGTPEKVSQHSHRHPFDYKGMSIFAVMIGSFTLLLTQGFEQGWFSTFSFICLSIFIITTLIFIIIERRHEVPFIDFSVLRNRPFIGAFLNNFVLNSGLGVTVVFFIYAQTHLGLSAAQSGLVTLPYAIVAVAMIRLGEKATLRFGGKLMLIIGPLFPVIGITIISMTQLSASQYVIAVIIGFVICAIGNGLVATPGLTIAIFSMPNEKVGLATGLYKMSGTLGGAFGIALSTTVFSMLQLNYAPSVAATVTFIVSIVLMILGSLSAYMIIPKTVKS
>CP028468.1|AWQ21848.1|268725_269718_+|linear-amide-C-N-hydrolase
MCTGFTIQTLNNQVLLGRTMDYDYPLDGSPAVTPRNYRWTSRTGTTGQTQYGFIGTGTDMEGFIYGDGVNEHGVAISTQYFRGYSSYGSTHKADAMNITQNEIVTWILGYTTSIEDMKQQASQIHVVAVYLNDIGEVPPLHYHVSDATGQSVEVSFKEGEVVIKDNPIGVLTNHPDLDWHYSNLRQYINISPYPATANLLEGVTIEPLGNEAGTFGLPGGFTSTERFVRMAFMKANIAQNNDKEMDLMNAFYLLDAVNIPIGIVRPHDADNHYTMYQTVINLTTRTLYIKYYGSNEIVALKLTDDLINRKDMTIFKPEKHITIRKLNDNQ
>CP028468.1|AWQ21849.1|270043_270991_+|glycine-glycine-endopeptidase-LytM
MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTQMSAQSQDVSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANANGSGQTYVNPATTGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNQAYNSHDGNGKVNYPNGTSNQNGGSASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPENSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPMSYLQSR
>CP028468.1|AWQ21850.1|271042_271702_-|ABC-transporter-ATP-binding-protein
MIEINNLSKRYRNKQIFNHLTMSFDSNRLTVLLGDNGAGKSTLLRMIAGIEKANDGTINYFGEKWNQRQIQNHIGYVPQDIALFEHMTVAENIKFFKSLCKNPINDTTINEYLQQLNFDDTSAKVSTLSGGNKRKINILVGLLGKPRILILDEPTVGIDLKSRHDIHQLLNIMKSKCLIILTTHHLDEVEALADDIKLIGQDPFYQHVLEDKQWTYTYY

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Crispr_ID: CP028468_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028468_2

606350-606437

Orphan

Consensus_repeat	Method
AAAAGAAATTCTACAGGCAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP028468_2

>merge|CP028468|2|606350-606437|CRISPRCasFinder
AAAAGAAATTCTACAGGCAATGCAAGTTGGGGTGTGGGCCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGGCAATGTAAGTTGG

>CP028468|2|2|606350-606437|CRISPRCasFinder
AAAAGAAATTCTACAGGCAATGCAAGTTGG	GGTGTGGGCCCCAACACAGAGAATTTCA
AAAAGAAATTCTACAGGCAATGTAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
CP028468.1\|AWQ22143.1\|602737_603373_+\|DUF443-domain-containing-protein	unknown	unknown	gnl\|CDD\|335700
CP028468.1\|AWQ22148.1\|606695_607232_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
CP028468.1\|AWQ24230.1\|609239_609761_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378039
CP028468.1\|AWQ22149.1\|607400_607877_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP028468.1\|AWQ22137.1\|597323_598400_+\|phosphomevalonate-kinase	unknown	unknown	gnl\|CDD\|130287
CP028468.1\|AWQ22152.1\|611498_612266_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|181681
CP028468.1\|AWQ22155.1\|614162_615824_+\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
CP028468.1\|AWQ22140.1\|600278_600719_-\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
CP028468.1\|AWQ22138.1\|598576_598918_+\|DUF1450-domain-containing-protein	unknown	unknown	gnl\|CDD\|377806
CP028468.1\|AWQ22146.1\|605259_606198_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
CP028468.1\|AWQ22139.1\|598969_600292_-\|FAD-containing-oxidoreductase	unknown	unknown	gnl\|CDD\|180907
CP028468.1\|AWQ22141.1\|600776_600878_+\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ22144.1\|603419_604040_+\|DUF443-domain-containing-protein	unknown	unknown	gnl\|CDD\|335700
CP028468.1\|AWQ24231.1\|613782_614166_+\|DUF1934-domain-containing-protein	unknown	unknown	gnl\|CDD\|226896
CP028468.1\|AWQ22153.1\|612462_613473_+\|zinc-dependent-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|181842
CP028468.1\|AWQ22151.1\|610251_611487_+\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
CP028468.1\|AWQ22150.1\|607916_609212_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
CP028468.1\|AWQ22142.1\|601342_602737_+\|transposase	unknown	unknown	gnl\|CDD\|368093
CP028468.1\|AWQ22154.1\|613549_613657_+\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ22145.1\|604179_604812_+\|DUF443-domain-containing-protein	unknown	unknown	gnl\|CDD\|335700

Protein	Function_ID	Function_description	E-value
CP028468.1\|AWQ22143.1\|602737_603373_+\|DUF443-domain-containing-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	8.51072e-61
CP028468.1\|AWQ22148.1\|606695_607232_+\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
CP028468.1\|AWQ24230.1\|609239_609761_+\|hypothetical-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98
CP028468.1\|AWQ22149.1\|607400_607877_+\|N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
CP028468.1\|AWQ22137.1\|597323_598400_+\|phosphomevalonate-kinase	gnl\|CDD\|130287	TIGR01220, phosphomevalonate_kinase, phosphomevalonate kinase, ERG8-type, Gram-positive branch. This enzyme is part of the mevalonate pathway, one of two alternative pathways for the biosynthesis of IPP. In an example of nonorthologous gene displacement, two different types of phosphomevalonate kinase are found - the animal type and this ERG8 type. This model represents the low GC Gram-positive organism forms of the ERG8 type of phosphomevalonate kinase. [Central intermediary metabolism, Other].	0
CP028468.1\|AWQ22152.1\|611498_612266_+\|AAA-family-ATPase	gnl\|CDD\|181681	PRK09183, PRK09183, transposase/IS protein; Provisional.	2.85352e-66
CP028468.1\|AWQ22155.1\|614162_615824_+\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
CP028468.1\|AWQ22140.1\|600278_600719_-\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	2.0619e-25
CP028468.1\|AWQ22138.1\|598576_598918_+\|DUF1450-domain-containing-protein	gnl\|CDD\|377806	pfam07293, DUF1450, Protein of unknown function (DUF1450). This family consists of several hypothetical bacterial proteins of around 80 residues in length. Members of this family contain four highly conserved cysteine residues. The function of this family is unknown.	8.95773e-05
CP028468.1\|AWQ22146.1\|605259_606198_+\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	1.11883e-166
CP028468.1\|AWQ22139.1\|598969_600292_-\|FAD-containing-oxidoreductase	gnl\|CDD\|180907	PRK07251, PRK07251, FAD-containing oxidoreductase.	0
CP028468.1\|AWQ22150.1\|607916_609212_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
CP028468.1\|AWQ22144.1\|603419_604040_+\|DUF443-domain-containing-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	3.87e-58
CP028468.1\|AWQ24231.1\|613782_614166_+\|DUF1934-domain-containing-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	9.50091e-54
CP028468.1\|AWQ22153.1\|612462_613473_+\|zinc-dependent-alcohol-dehydrogenase	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
CP028468.1\|AWQ22151.1\|610251_611487_+\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.13094e-34
CP028468.1\|AWQ22142.1\|601342_602737_+\|transposase	gnl\|CDD\|368093	pfam04740, LXG, LXG domain of WXG superfamily. This domain is present is the N-terminal region of a group of polymorphic toxin proteins in bacteria. It is predicted to use Type VII secretion pathway to mediate export of bacterial toxins.	1.09874e-10
CP028468.1\|AWQ22145.1\|604179_604812_+\|DUF443-domain-containing-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	2.26478e-44

>CP028468.1|AWQ22146.1|605259_606198_+|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDDNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKLAEQVVENIKAADIVLSDDEIQYIDELFPIED
>CP028468.1|AWQ22145.1|604179_604812_+|DUF443-domain-containing-protein
MLCEVIAIYKNPKYRIIKYNDEYLMVNIINNWLVLFIPLLNWLTPKRYIKISQEELESLNTFKPAKNNAFWPALGSSVLFSVTFRKYMPLFNVRLEKTIVIAIFFVVFLGILFFYLNLNRRLALSVFTMNKEKSQKMILLPNLKHFFFIIFAYLYFGGFSFFTLYALITIDVQNIIIFICWGAVTMFFFFINIVPIGIKKAHVILLKKAE
>CP028468.1|AWQ22144.1|603419_604040_+|DUF443-domain-containing-protein
MLCESKIINKNPKYRIIKYNDEYLMIDIISTWISLFFPFINWFITKRYVKISREEFENLNIVKPAKKNVFWPVAGSSALLGVALRKYTHLLDVQLDKKLVIAICCITFIGILIFYVRLIKKSSLNIYNTKNKRSKIFLIPTLKNVCFTLFGYILFGGLTMLFLDALLSMSYQNIIVYFAWITAIMGFFLVNIALIIDKNIHVILKN
>CP028468.1|AWQ22143.1|602737_603373_+|DUF443-domain-containing-protein
MLLCESKVINKNPKYRIIKYESEYLMIDLASNWIVFFFPFINWLIPKTYVKITKNDYEKLNIVKPVKNKSIGWTIFAGIVLLGGTVRRNTYLFDFQLEKLIVWSSCFISFLGVIFFYCYLNKKLTLNVYKENKNNELKLRLLPSFKNMCFTIFYYLFTGFMSYGAFYLLVFENVQNLILYISWLFMTMLFMLMNMHSIIDKKVHIFLKSNK
>CP028468.1|AWQ22142.1|601342_602737_+|transposase
MSIDMYLDRSRNQASSVGNLSQTMNSNYDALEKAITQFINDDALKGKAYTSAKQFFSTVLIPLSTSMKTLSDLTKQACDNFVSRYTSEVDSISLKESELEEDIRSLSQQITRYENLTNNLKKHASDNQQAISSNQQIIQTLGQQKHELEEKLRKLREFNQKSPEIFKEVEEFQKIVQQGLTQAQNFWNFSTNQFNIPSGKELDWAKASHEKYLKVAMGKIEHKAEKETLNKADFAVIKAYAKEHPEDDIPKSIMKYINDNKDSIKRDIGLDITSTLLEQGGINASKFGVFINTAGGVKGPAGPNSFVEVKRTSGNVFIENGSKFAKGGKYLGKGVAGVGFGIGMYDDLANDDKTFGEALSHNGMTLAAGSVAAFGVAALVSNPVGWAVVGILTAGIIGSIVSDYLYQNNYFGIKDKVDWAGHKIDEGIDAVNKTAEKAVDSVGNTIGDATKSISNHINPMKWSW
>CP028468.1|AWQ22141.1|600776_600878_+|hypothetical-protein
MCQYLCLKSVELGVVIVMIYCLKVVALTVRLHN
>CP028468.1|AWQ22140.1|600278_600719_-|Rrf2-family-transcriptional-regulator
MNLEFNIAVHVLAFLTKHHSEKFNSSSLAELTCLNPVQLRRVTTQLVDLKMINTIRGKDGGYLANDQSADVSLATLYKHFVLEKKHHTRLFTGDEGSHCQIARNIATTMSHYQQDEQNIIINFYNGKTIKDVIEDIQKEDLCHENI
>CP028468.1|AWQ22139.1|598969_600292_-|FAD-containing-oxidoreductase
MKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSSKMYGGTCINIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNALNNKNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHGDIADSITAPHIIINTGATSVIPNIKDLDQAKHVFDSTGLLNINYQPKHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPREDQDVVAHAITDLENKGIALHTNVETTELSSDDHHTTVRTNVGNFEADAVLLAIGRKPNTDLALENTDIELGDRGEIKVNAHLQTTVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGNQSRTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTEHQLLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQSEELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLFNF
>CP028468.1|AWQ22138.1|598576_598918_+|DUF1450-domain-containing-protein
MKNTFLICDECQAVNIRTLQKKLEKLDPDAEIVIGCQSYCGPGRRKTFTFVNNRPLAALTEEELIEKVSQQLKKPRDSEEEERLRKRHEERKRRKEEQDRKLKEKLEKRKAQQ
>CP028468.1|AWQ22137.1|597323_598400_+|phosphomevalonate-kinase
MIQVKAPGKLYIAGEYAVTEPGYKSVLIALDRFVTATIEEADQYKGTIHSKALHHNPVTFSRDEDSIVISDPHAAKQLNYVVTAIEIFEQYAKSCDIAMKHFHLTIDSNLDDSNGHKYGLGSSAAVLVSVIKVLNEFYDMKLSNLYIYKLAVIANMKLQSLSSCGDIAVSVYSGWLAYSTFDHEWVKHQIEDTTVEEVLIKNWPGLHIEPLQAPENMEVLIGWTGSPASSPHFVSEVKRLKSDPSFYGDFLEDSHRCVEKLIHAFKTNNIKGVQKMVRQNRTIIQRMDKEATVDIETEKLKYLCDIAEKYHGASKTSGAGGGDCGITIINKDVDKEKIYDEWTKHGIKPLKFNIYHGQ
>CP028468.1|AWQ22148.1|606695_607232_+|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>CP028468.1|AWQ22149.1|607400_607877_+|N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>CP028468.1|AWQ22150.1|607916_609212_+|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>CP028468.1|AWQ24230.1|609239_609761_+|hypothetical-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>CP028468.1|AWQ22151.1|610251_611487_+|IS21-family-transposase
MRHDIYEGVLFYIMKGIKPNYAELGRQYNCDPRTVKKYYEAGKENELERLKKRQQNKKASKLDPFKEIINKKIELGCTAMAIFKYIEKKGYEGKYTILREYCKNKKQNETKKATIRVETNPGIAAQVDWKEDMVMHDKFGRTYQFNIFLYVLHYSKMKYITLTWDRKQDTLFECLKDAFEYTEGVPKEIWFDNMRTVVDRPRTQYKKVVFNNLFYQFSKDANFEPIACRPYRPQTKGSVESLAKFVEQRLRPYDYEFYDAVELIGLVNDLCHELNHLEISQATEQRPIDVFNYEEKEHLNSFNAKLLDTYIENECIRIVSKESMINFRKGKYSVPTKYIGEEVQVIFNNSTDELLIYYDGELIRRHNLSERKFNYIVEDMSEILKSDVFKHKDDKEILTYIENSLLLYDEI
>CP028468.1|AWQ22152.1|611498_612266_+|AAA-family-ATPase
MNTNHQKLLNNFEILKLKKFKDYYPNYIELLSKNEKSLTEILIDLTEKEIEYQSELKFKRAVNSARFPKIKYLHDFDFMFQPSINQQEILTLKSMHFLEDSINICFLGNSGVGKTHLAISLGIEACKQNIKTRFYTFKELIDLLTVSDSKGIINKTLKQLSRIELLIIDEIGYTPITKEQADLFYQLMSLRYEWKSTIITTNIPFSSWGESFSNKIVSAAIIDRLVHHSKVFKITGESYRLKDYKTEKSLNIRQS
>CP028468.1|AWQ22153.1|612462_613473_+|zinc-dependent-alcohol-dehydrogenase
MRAAVVTKDHKVSIEDKKIRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>CP028468.1|AWQ22154.1|613549_613657_+|hypothetical-protein
MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN
>CP028468.1|AWQ24231.1|613782_614166_+|DUF1934-domain-containing-protein
MLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>CP028468.1|AWQ22155.1|614162_615824_+|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM

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Crispr_ID: CP028468_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028468_3

890309-890393

Orphan

Consensus_repeat	Method
TTTTCGAAATTCTCTGTGTTTGGGCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP028468_3

>merge|CP028468|3|890309-890393|CRISPRCasFinder
TTTTCGAAATTCTCTGTGTTTGGGCCCGCTCCCCAACTCGCATTGCTTGTAGAATTTCTTTTTGAAATTCTCTGTGTTTGGGCCC

>CP028468|3|3|890309-890393|CRISPRCasFinder
TTTTCGAAATTCTCTGTGTTTGGGCCC	GCTCCCCAACTCGCATTGCTTGTAGAATTTC
TTTTTGAAATTCTCTGTGTTTGGGCCC

Protein	Signature genes	Signature genes Name	Protein_function
CP028468.1\|AWQ22430.1\|900238_900673_+\|MAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|367591
CP028468.1\|AWQ22422.1\|889922_890231_+\|metal-sulfur-cluster-assembly-factor	unknown	unknown	gnl\|CDD\|225062
CP028468.1\|AWQ22416.1\|878535_882012_+\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736
CP028468.1\|AWQ22420.1\|887616_888933_-\|CoA-disulfide-reductase	unknown	unknown	gnl\|CDD\|184103
CP028468.1\|AWQ22427.1\|897679_898321_+\|Sua5/YciO/YrdC/YwlC-family-protein	unknown	unknown	gnl\|CDD\|223088
CP028468.1\|AWQ22429.1\|899412_899928_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|224793
CP028468.1\|AWQ22431.1\|900929_901115_-\|DUF2929-domain-containing-protein	unknown	unknown	gnl\|CDD\|371396
CP028468.1\|AWQ22415.1\|877800_878376_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
CP028468.1\|AWQ22424.1\|892903_895513_+\|chaperone-protein-ClpB	unknown	unknown	gnl\|CDD\|274529
CP028468.1\|AWQ22417.1\|882012_885666_+\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
CP028468.1\|AWQ22419.1\|887056_887446_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237465
CP028468.1\|AWQ22418.1\|885829_886732_+\|FAA-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
CP028468.1\|AWQ22425.1\|895571_896441_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
CP028468.1\|AWQ22423.1\|890885_892700_+\|acyltransferase	unknown	unknown	gnl\|CDD\|224748
CP028468.1\|AWQ22413.1\|876680_877256_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
CP028468.1\|AWQ22421.1\|888984_889809_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
CP028468.1\|AWQ22428.1\|898313_899435_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
CP028468.1\|AWQ22426.1\|896550_897696_+\|2-isopropylmalate-synthase	unknown	unknown	gnl\|CDD\|223197
CP028468.1\|AWQ22414.1\|877260_877785_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
CP028468.1\|AWQ22432.1\|901409_902351_+\|3-oxoacyl-ACP-synthase-III	unknown	unknown	gnl\|CDD\|236475

Protein	Function_ID	Function_description	E-value
CP028468.1\|AWQ22430.1\|900238_900673_+\|MAP-domain-containing-protein	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	1.04833e-34
CP028468.1\|AWQ22422.1\|889922_890231_+\|metal-sulfur-cluster-assembly-factor	gnl\|CDD\|225062	COG2151, PaaD, Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only].	1.55915e-41
CP028468.1\|AWQ22416.1\|878535_882012_+\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
CP028468.1\|AWQ22420.1\|887616_888933_-\|CoA-disulfide-reductase	gnl\|CDD\|184103	PRK13512, PRK13512, coenzyme A disulfide reductase; Provisional.	0
CP028468.1\|AWQ22427.1\|897679_898321_+\|Sua5/YciO/YrdC/YwlC-family-protein	gnl\|CDD\|223088	COG0009, SUA5, Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis].	3.6208e-55
CP028468.1\|AWQ22429.1\|899412_899928_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|224793	COG1881, COG1881, Phospholipid-binding protein [General function prediction only].	7.30186e-43
CP028468.1\|AWQ22431.1\|900929_901115_-\|DUF2929-domain-containing-protein	gnl\|CDD\|371396	pfam11151, DUF2929, Protein of unknown function (DUF2929). This family of proteins with unknown function appears to be restricted to Firmicutes.	3.295e-11
CP028468.1\|AWQ22415.1\|877800_878376_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	9.57816e-54
CP028468.1\|AWQ22424.1\|892903_895513_+\|chaperone-protein-ClpB	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
CP028468.1\|AWQ22417.1\|882012_885666_+\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
CP028468.1\|AWQ22419.1\|887056_887446_+\|hypothetical-protein	gnl\|CDD\|237465	PRK13673, PRK13673, hypothetical protein; Provisional.	2.91098e-33
CP028468.1\|AWQ22418.1\|885829_886732_+\|FAA-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.74159e-87
CP028468.1\|AWQ22425.1\|895571_896441_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	3.64595e-38
CP028468.1\|AWQ22423.1\|890885_892700_+\|acyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	4.21639e-82
CP028468.1\|AWQ22413.1\|876680_877256_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	2.59702e-40
CP028468.1\|AWQ22421.1\|888984_889809_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.66336e-85
CP028468.1\|AWQ22428.1\|898313_899435_+\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.7725e-05
CP028468.1\|AWQ22426.1\|896550_897696_+\|2-isopropylmalate-synthase	gnl\|CDD\|223197	COG0119, LeuA, Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism].	1.29632e-86
CP028468.1\|AWQ22414.1\|877260_877785_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	6.16967e-49
CP028468.1\|AWQ22432.1\|901409_902351_+\|3-oxoacyl-ACP-synthase-III	gnl\|CDD\|236475	PRK09352, PRK09352, beta-ketoacyl-ACP synthase 3.	0

>CP028468.1|AWQ22422.1|889922_890231_+|metal-sulfur-cluster-assembly-factor
MEEALKDSILGALEMVIDPELGIDIVNLGLVYKVNVDDEGVCTVDMTLTSMGCPMGPQIIDQVKTVLAEIPEIQDTEVNIVWSPPWTKDMMSRYAKIALGVS
>CP028468.1|AWQ22421.1|888984_889809_-|Cof-type-HAD-IIB-family-hydrolase
MQPHLICLDLDGTLLNDNKEISSYTKQVLNELQQRGHQIMIATGRPYRASQMYYHELNLTTPIVNFNGAYVHHPKDKNFKTCHEILDLGIAQNIIQGLQQYQVSNIIAEVKDYVFINNHDPRLFEGFSMGNPRIQTGNLLVHLKESPTSILIEAEESKIPEIKNMLTHFYADHIEHRRWGAPFPVIEIVKLGINKARGIEQVRQFLNIDRNNIIAFGDEDNDIEMIEYARHGVAMENGLQELKDVANNITFNNNEDGIGRYLNDFFNLNIRYYC
>CP028468.1|AWQ22420.1|887616_888933_-|CoA-disulfide-reductase
MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRKYALAYTPEKFYDRKQITVKTYHEVIAINDERQTVTVLNRKTNEQFEESYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVVGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDTDMNQPILDELDKREIPYRLNEEIDAINGNEITFKSGKVEHYDMIIEGVGTHPNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLTASVPLAWGAHRAASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK
>CP028468.1|AWQ22419.1|887056_887446_+|hypothetical-protein
MLHLHILSWVLAIILFIATYLNISKNQGGSPFFKPLHMILRLFMLLTLISGFWILIQSFMNGGANHMLLTLKMLCGVAVVGLMEVSIAKRKRHEQSHTMFWITIALIIITMVLGVILPLGPISKLFGIG
>CP028468.1|AWQ22418.1|885829_886732_+|FAA-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVERLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK
>CP028468.1|AWQ22417.1|882012_885666_+|helicase-exonuclease-AddAB-subunit-AddA
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKANDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGAEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTINGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVNYDESAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEVADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYKAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQVEDSSRPNVNISIIYFEDVSTETILDNNEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>CP028468.1|AWQ22416.1|878535_882012_+|helicase-exonuclease-AddAB-subunit-AddB
MTLHAYLGRAGTGKSTKMLTEIKQKMKQDPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFKQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFKQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEQILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>CP028468.1|AWQ22415.1|877800_878376_+|signal-peptidase-I
MKKELLEWIISIAVAFVILFIVGKFIVTPYMIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>CP028468.1|AWQ22414.1|877260_877785_+|signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDYDNNQHDSRQFGLIDKKDIIGNISLRYYPFSKWTIQFKS
>CP028468.1|AWQ22413.1|876680_877256_+|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRWVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTQPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE
>CP028468.1|AWQ22423.1|890885_892700_+|acyltransferase
MNKTKGFTKYKKMRYMPGLDGLRAIAVLGIIIYHLNKQWLTGGFLGVDTFFVISGYLITSLLLKEYDDTGIIKLKSFWIRRLKRLLPAVIVLLMVVGTATLLLKSDNIIRVKHDIIAAIFYVSNWWYIAKDVNYFEQFSFMPLKHLWSLAIEEQFYIFFPVILVTLLLTIKKRYKIGFIFWGVSIISLGLMMFIYSINGDHSRVYFGTDTRLQTLLLGVILAFLWPPFKLKNDPPKVVKYVIDSIGSLSFIILILLFFIINDETNWIYDGGFYLISILTLFIIASVVHPSTWIAKIFSNPVLVFIGKRSYSLYLWHFAVISFVHSYYVDGQIPVYVYFIDISLTIIFAELSYRFIETPFRKEGIKALNWRPSYIPQFIRMAIVVTLLIPFMLILVGAFNKYGKDIIGEKANSFDTTIEDNYLMRIAPIDNIHIDGLVSEKKKESSDVYNNIKPLLIGDSVMVDIGESFKSSVPKSRIDGKVGRQLYQTLPLVKANYSQYKKSSDQVVLELGTNGDFTVKQLDDLLNQFGKAKIYLVNTRVPRIYEANVNRLLADAAKRKSNVTLIDWYKRSQGHSEYFAPDGVHLEYKGVLALKDEILKALKKK
>CP028468.1|AWQ22424.1|892903_895513_+|chaperone-protein-ClpB
MDINKMTYAVQSALQQAVELSQQHKLQNIEIEAILSAALNESESLYKSILERANIEVDQLNKAYEDKLNTYASVEGDNIQYGQYISQQANQLITKAESYMKEYEDEYISMEHILRSAMDIDQTTKHYINNKVEVIKEIIKKVRGGNHVTSQNPEVNYEALAKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPESLLDKTVFELDLSALVAGAKYRGEFEERLKAVLKEVKESDGRIILFIDEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYREYIEKDSALERRFQKVAVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDLVDQACATIRTEMGSNPTELDQVNRRVMQLEIEESALKNESDNASKQRLQELQEELANEKEKQAALQSRVESEKEKIANLQEKRAQLDESRQALEDAQTNNNLEKAAELQYGTIPQLEKELRELEDNFQDEQGEDTDRMIREVVTDEEIGDIVSQWTGIPVSKLVETEREKLLHLSDILHKRVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLAASLFDSEKHMIRIDMSEYMEKHAVSRLIGAPPGYIGHDEGGQLTEAVRRNPYSVILLDEVEKAHTDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIMTSNIGSQVLLENVKETGEITESTEKAVMTSLNAYFKPEILNRMDDIVLFKPLSIDDMSMIVDKILTQLNIRLLEQRISIEVSDDAKAWLGQEAYEPQYGARPLKRFVQRQIETPLARMMIKEGFPEGTTIKVNLNSDNNLTFNVEKIHE
>CP028468.1|AWQ22425.1|895571_896441_-|LysR-family-transcriptional-regulator
MNLDWYYTFVILAKTLNYRLASEEINLTIPSIHKQIKNLEQHLNVKLFETYKNQIILTEDGHTFLPIAQSFIEQYESGIKHIQLKKTMFQSKLNVVVSSYIATFIMPKFLKSFFNEHPFIDVSLHVKNENIEKDINNHTYDIGISRNQPKLREVHSEKVCEGKIVLIAPNKENNHLLTEASLFEKYKIISDNHPEYWSSLKNNILNIYEKAQFLSINDVHTSIKLIEMNQGISFLPIYITTDSDYNISVINTKILQAPISFTYIYSKKESPEILAFIRSFKKYIANEQL
>CP028468.1|AWQ22426.1|896550_897696_+|2-isopropylmalate-synthase
MIRIQDNTIRDGMQQSNVRKSIIVKKEVLQEINKISINSVEVGMCTTFEDEYNIHQYREILNNDKEIVVLTRLDENEINKILNLKIHNLAVKILLPISDLHIKEKLNFTSEYYNERINKCLNMIKVNQVAIDICFEDATRCSLEKLCEYMEMISKFPIRTVTFADTVGCSTPFEYGNIFKEFVKKYPNITFSAHCHNDLGLATANTFAAILNGAQQIETTFLGIGERAGNASIEEIIAILTKKQIVMTSLNLPDIYKTSMNISKILDIRLAENKPVIGKNIFKHESGIHQDGTNKNISMYQYILPSDLGLKNSKAVQFPISNISSKKILKNKFKSIVHPKDIEENISFYKLINKFIPEVVPEDTADLLQVIKGRSKDGNFK
>CP028468.1|AWQ22427.1|897679_898321_+|Sua5/YciO/YrdC/YwlC-family-protein
MEILNESVESFEKLYLQLQNSYPIIVPTDTNYNLCSLSNNKICIDRIFKYKKRSKDKPLSLFIDEPEDWKLYGENKNVELVDKLVNIFWPGPLNIILKNKTNYNYMLNNSDSIAIGCVQNKTMRNLISYIQSPIAITSANISGTADDILITENEAIKHMGNNVNYMLRSKNKSKYKSSSTIIKVTGNKIELLREGDIKFEEIKAKLGSGIQYE
>CP028468.1|AWQ22428.1|898313_899435_+|MFS-transporter
MNKLILGIYLYRILSRAYFYLPFLLIYFLAQNYSIMQLEILMATYGVAAFLFGLYKEKIFRIYQIKDAYKLIVSEVFKIIGLILLLYPSHFYILLVAQLLLGLSYSIMAGVDTSIIKMNIKNHKLIQNKSNGYMFLSLLISGIIGSYLYGINIKWPIYMTGLFSILTILVILLTLVENVDCNIKSESKRKRKKLLADEKFWVLHYSFLRALILGFFVGFIPINLYIDLKLNNVQFISVLTSYTIMGYISSRYLTRYLNYKFLSEICLVIFLIIYTFQNIIAITIAILFLGISSGLTRPQTINELSNSSNLAAILNYAETLYFIFNIAFLLIGGYLYSIGTIQYLMLFMSLLTFIYLLTLFYLRRDQHENQHRI
>CP028468.1|AWQ22429.1|899412_899928_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MKINTEFKGNNIPYEYAAGADISDLINGNPIKSFPFEITELPKDTKYLAWSLIDYDAIPVCGFAWIHWSVANVSVTRDSISIKPDLSRTKGDYVQGKNSFTSGLLADDFSEIENHYVGPTPPDQDHQYELTVYALDHSLNLKNGFYLNEFLKEVNQHKIDQTSINLIGRKI
>CP028468.1|AWQ22430.1|900238_900673_+|MAP-domain-containing-protein
MKLKSFITVTLALGMIATTGATVASNEVSAAEKDKQPATQKAKEMQNVPYTIAVDGIMAFNQSYLNLPKDSQLSYLDLGNKVKALLYDERGVTPEKIRNAKSAVYTITWKDSSKKEVDLKKDSYTANLFDSNSIKQIDINVKTK
>CP028468.1|AWQ22431.1|900929_901115_-|DUF2929-domain-containing-protein
MKHLVTFFWALLLMQMVNFVLNSLVGGDSLNLVNPIIMAVLFTIFTAIFAAVIKPPKDSSQ
>CP028468.1|AWQ22432.1|901409_902351_+|3-oxoacyl-ACP-synthase-III
MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASVKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSEGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKLKDDDTIVLVGFGGGLTWGAMTIKWGK

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Crispr_ID: CP028468_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028468_4

1897690-1897779

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGCCTGTAGAATTTCTTTT	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of CP028468_4

>merge|CP028468|4|1897690-1897779|CRISPRCasFinder
CCCCAACTTGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCACACCCCAACTTGCATTGCCTGTAGAATTTCTTTT

>CP028468|4|4|1897690-1897779|CRISPRCasFinder
CCCCAACTTGCATTGCCTGTAGAATTTCTTTT	CGAAATTCTCTGTGTTGGGGCCCACA
CCCCAACTTGCATTGCCTGTAGAATTTCTTTT

Protein	Signature genes	Signature genes Name	Protein_function
CP028468.1\|AWQ23344.1\|1895478_1896180_-\|transporter	unknown	unknown	gnl\|CDD\|227100
CP028468.1\|AWQ23351.1\|1902477_1902978_+\|non-heme-ferritin	unknown	unknown	gnl\|CDD\|224445
CP028468.1\|AWQ23343.1\|1894438_1895482_-\|two-component-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
CP028468.1\|AWQ23342.1\|1893819_1894449_-\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|225107
CP028468.1\|AWQ23347.1\|1898084_1899071_+\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
CP028468.1\|AWQ23352.1\|1903059_1903152_-\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ24272.1\|1899501_1899915_-\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ23350.1\|1900872_1902186_-\|DUF1727-domain-containing-protein	unknown	unknown	gnl\|CDD\|223840
CP028468.1\|AWQ23353.1\|1903367_1903922_+\|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
CP028468.1\|AWQ23354.1\|1903989_1905060_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
CP028468.1\|AWQ23340.1\|1891936_1892212_+\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ23349.1\|1900139_1900871_-\|glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
CP028468.1\|AWQ23338.1\|1889859_1891116_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723
CP028468.1\|AWQ23341.1\|1892489_1893707_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
CP028468.1\|AWQ23346.1\|1896797_1897556_-\|methionine-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
CP028468.1\|AWQ23355.1\|1905306_1905837_-\|DUF3267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378690
CP028468.1\|AWQ23348.1\|1899943_1900054_-\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ23339.1\|1891465_1891930_+\|protein-tyrosine-phosphatase	unknown	unknown	gnl\|CDD\|319971
CP028468.1\|AWQ24271.1\|1891118_1891319_-\|DUF1128-domain-containing-protein	unknown	unknown	gnl\|CDD\|227177
CP028468.1\|AWQ23345.1\|1896194_1896581_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP028468.1\|AWQ23344.1\|1895478_1896180_-\|transporter	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
CP028468.1\|AWQ23351.1\|1902477_1902978_+\|non-heme-ferritin	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
CP028468.1\|AWQ23343.1\|1894438_1895482_-\|two-component-sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
CP028468.1\|AWQ23342.1\|1893819_1894449_-\|DNA-binding-response-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.75115e-79
CP028468.1\|AWQ23347.1\|1898084_1899071_+\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.20478e-76
CP028468.1\|AWQ24271.1\|1891118_1891319_-\|DUF1128-domain-containing-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	9.24488e-25
CP028468.1\|AWQ23353.1\|1903367_1903922_+\|DNA-polymerase-III-subunit-epsilon	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
CP028468.1\|AWQ23354.1\|1903989_1905060_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
CP028468.1\|AWQ23350.1\|1900872_1902186_-\|DUF1727-domain-containing-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	3.37755e-99
CP028468.1\|AWQ23338.1\|1889859_1891116_-\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
CP028468.1\|AWQ23341.1\|1892489_1893707_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	4.24482e-85
CP028468.1\|AWQ23346.1\|1896797_1897556_-\|methionine-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126
CP028468.1\|AWQ23355.1\|1905306_1905837_-\|DUF3267-domain-containing-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.92343e-11
CP028468.1\|AWQ23339.1\|1891465_1891930_+\|protein-tyrosine-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
CP028468.1\|AWQ23349.1\|1900139_1900871_-\|glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	3.33663e-121

>CP028468.1|AWQ23346.1|1896797_1897556_-|methionine-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>CP028468.1|AWQ23345.1|1896194_1896581_-|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>CP028468.1|AWQ23344.1|1895478_1896180_-|transporter
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>CP028468.1|AWQ23343.1|1894438_1895482_-|two-component-sensor-histidine-kinase
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>CP028468.1|AWQ23342.1|1893819_1894449_-|DNA-binding-response-regulator
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>CP028468.1|AWQ23341.1|1892489_1893707_+|YihY/virulence-factor-BrkB-family-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIIFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>CP028468.1|AWQ23340.1|1891936_1892212_+|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>CP028468.1|AWQ23339.1|1891465_1891930_+|protein-tyrosine-phosphatase
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>CP028468.1|AWQ24271.1|1891118_1891319_-|DUF1128-domain-containing-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHD
>CP028468.1|AWQ23338.1|1889859_1891116_-|aminopeptidase
MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHELKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAEKGETVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF
>CP028468.1|AWQ23347.1|1898084_1899071_+|aromatic-acid-exporter-family-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>CP028468.1|AWQ24272.1|1899501_1899915_-|hypothetical-protein
MKPTKVILRDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEVKFEFALFDSDMDNLKHMDYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVAKSDFTKFINELASLH
>CP028468.1|AWQ23348.1|1899943_1900054_-|hypothetical-protein
MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT
>CP028468.1|AWQ23349.1|1900139_1900871_-|glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
>CP028468.1|AWQ23350.1|1900872_1902186_-|DUF1727-domain-containing-protein
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYSVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>CP028468.1|AWQ23351.1|1902477_1902978_+|non-heme-ferritin
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>CP028468.1|AWQ23352.1|1903059_1903152_-|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>CP028468.1|AWQ23353.1|1903367_1903922_+|DNA-polymerase-III-subunit-epsilon
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>CP028468.1|AWQ23354.1|1903989_1905060_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGLTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>CP028468.1|AWQ23355.1|1905306_1905837_-|DUF3267-domain-containing-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLFLLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ

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Crispr_ID: CP028468_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028468_5

2020515-2020603

Orphan

Consensus_repeat	Method
GTTTTTGACTGACTTCTCAATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP028468_5

>merge|CP028468|5|2020515-2020603|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCAATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAGTTTTTCGACTGACTTCTCAATCA

>CP028468|5|5|2020515-2020603|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCA	ATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAG
TTTTTCGACTGACTTCTCAATCA

Protein	Signature genes	Signature genes Name	Protein_function
CP028468.1\|AWQ23496.1\|2022598_2024215_-\|molecular-chaperone-GroEL	unknown	unknown	gnl\|CDD\|234573
CP028468.1\|AWQ23498.1\|2024751_2025495_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
CP028468.1\|AWQ23486.1\|2016257_2017967_-\|DUF927-domain-containing-protein	unknown	unknown	gnl\|CDD\|227806
CP028468.1\|AWQ23501.1\|2027871_2028657_+\|carbon-nitrogen-family-hydrolase	unknown	unknown	gnl\|CDD\|143607
CP028468.1\|AWQ23489.1\|2019231_2019615_-\|pathogenicity-island-protein	unknown	unknown	unknown
CP028468.1\|AWQ23499.1\|2025519_2026779_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236768
CP028468.1\|AWQ23495.1\|2021357_2022530_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
CP028468.1\|AWQ23494.1\|2020669_2021344_+\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
CP028468.1\|AWQ23502.1\|2029062_2029830_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|181681
CP028468.1\|AWQ23497.1\|2024290_2024575_-\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
CP028468.1\|AWQ23484.1\|2014927_2015569_-\|pathogenicity-island-protein	unknown	unknown	gnl\|CDD\|374630
CP028468.1\|AWQ23493.1\|2020278_2020497_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
CP028468.1\|AWQ23490.1\|2019616_2019820_-\|pathogenicity-island-protein	unknown	unknown	unknown
CP028468.1\|AWQ23488.1\|2018913_2019231_-\|DUF1474-domain-containing-protein	unknown	unknown	gnl\|CDD\|369323
CP028468.1\|AWQ23485.1\|2015565_2015946_-\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ23503.1\|2029841_2031077_-\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
CP028468.1\|AWQ23500.1\|2026975_2027602_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
CP028468.1\|AWQ23491.1\|2019804_2019960_-\|pathogenicity-island-protein	unknown	unknown	unknown
CP028468.1\|AWQ23492.1\|2019956_2020274_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|200128
CP028468.1\|AWQ23487.1\|2017980_2018850_-\|mobile-element-associated-protein	unknown	unknown	gnl\|CDD\|214926

Protein	Function_ID	Function_description	E-value
CP028468.1\|AWQ23496.1\|2022598_2024215_-\|molecular-chaperone-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
CP028468.1\|AWQ23486.1\|2016257_2017967_-\|DUF927-domain-containing-protein	gnl\|CDD\|227806	COG5519, COG5519, Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair].	4.69521e-166
CP028468.1\|AWQ23499.1\|2025519_2026779_-\|hypothetical-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	3.95542e-09
CP028468.1\|AWQ23495.1\|2021357_2022530_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	5.10093e-47
CP028468.1\|AWQ23494.1\|2020669_2021344_+\|XRE-family-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.58614e-10
CP028468.1\|AWQ23502.1\|2029062_2029830_-\|AAA-family-ATPase	gnl\|CDD\|181681	PRK09183, PRK09183, transposase/IS protein; Provisional.	2.85352e-66
CP028468.1\|AWQ23497.1\|2024290_2024575_-\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	5.94304e-45
CP028468.1\|AWQ23484.1\|2014927_2015569_-\|pathogenicity-island-protein	gnl\|CDD\|374630	pfam16560, SAPI, Putative mobile pathogenicity island. SAPI is a family of putative Gram-positive mobile pathogenicity island proteins. SAPIs are responsible for many superantigen-related diseases in humans as they carry two or more superantigens.	2.52046e-113
CP028468.1\|AWQ23493.1\|2020278_2020497_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	9.85461e-11
CP028468.1\|AWQ23488.1\|2018913_2019231_-\|DUF1474-domain-containing-protein	gnl\|CDD\|369323	pfam07342, DUF1474, Protein of unknown function (DUF1474). This family consists of several bacterial proteins of around 100 residues in length. Members of this family seem to be found exclusively in Staphylococcus aureus. The function of this family is unknown.	2.13556e-19
CP028468.1\|AWQ23501.1\|2027871_2028657_+\|carbon-nitrogen-family-hydrolase	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	1.6362e-126
CP028468.1\|AWQ23503.1\|2029841_2031077_-\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.13094e-34
CP028468.1\|AWQ23500.1\|2026975_2027602_+\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	5.71771e-116
CP028468.1\|AWQ23498.1\|2024751_2025495_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.01871e-11
CP028468.1\|AWQ23492.1\|2019956_2020274_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	5.89089e-17
CP028468.1\|AWQ23487.1\|2017980_2018850_-\|mobile-element-associated-protein	gnl\|CDD\|214926	smart00942, PriCT_1, Primase C terminal 1 (PriCT-1). This alpha helical domain is found at the C terminal of primases.	2.61429e-15

>CP028468.1|AWQ23493.1|2020278_2020497_-|XRE-family-transcriptional-regulator
MTILANTRKFKEAMFLKGFNLSDLSRETGVGISYLSQIINGKKIPSPKLAKKMAEVLQVEVNELFEFEVKEA
>CP028468.1|AWQ23492.1|2019956_2020274_-|helix-turn-helix-domain-containing-protein
MFNINIDEDEARELLEQAINARVDELAKEKYFMTYKELSNYLNLSKPTIEELLINNGMKYYMVGSTYRFKKSDVDEFMEQLTAHMNIQNNDFKQVNIKKLLEARQ
>CP028468.1|AWQ23491.1|2019804_2019960_-|pathogenicity-island-protein
MKIYLTYICLVSLLTILLLAISNMYVAFSVYAWLITLGCNLTGEITTCENK
>CP028468.1|AWQ23490.1|2019616_2019820_-|pathogenicity-island-protein
MRKQVIITKTVVGWYNIKDTQHNLMLNIPPKVFEQYFPDVSKDVQVVCLEMDLSKITEIKNKKKVGS
>CP028468.1|AWQ23489.1|2019231_2019615_-|pathogenicity-island-protein
MEIKQKYQLSKVVKILEVVLYEEDKFQSDKDYHYQDKALYEYALKLVHNGLFNILAELDFEDEAFLILDEVTMTLSDVMKETQHVYRYSVIDEKGEHKHTTDRKGHVIGMLEWALDYIAGNIEVEEL
>CP028468.1|AWQ23488.1|2018913_2019231_-|DUF1474-domain-containing-protein
MNWEIKDLMCDIEAVKEKINDVAIKHAWFVEDRFVKNELETKREHINFSASYLEHRIQNEHTVELLHVYLKEFGELIQKFHEIEKASSENFGEVSDDAQKLKITE
>CP028468.1|AWQ23487.1|2017980_2018850_-|mobile-element-associated-protein
MNEIKLEYDTHVSVVHYESLDSRSFNSFSKINWSKLVNKLSVPIEANYKYARGVAVYGDIKNGANDQGEIIKKHRNDKNVIYRDVIVLDYDEINDLKQLHEAISSALSNVAWFWHTSYSHRTEQARIRLYIPLNERISADDYRKYTKVLANKIGHKVDEGSYQPSRCFALPVIQKGHIFIKRVNDCPIMNVDMLEQWSKEFEQSNASPNVIGYTRRDSEYWRELCFGTTEGNRNNALASLIGHLLRCHVNDYIVYSFALLWGQFACKPPMKEQEINATFQSILNKHYNN
>CP028468.1|AWQ23486.1|2016257_2017967_-|DUF927-domain-containing-protein
METGKSDVLDKIEKINKKDSALQEIIPKGYEIEHHQCGIALNQLIPSKKEGEPDKKVFITSTIPQITERFEDIESNEVSFNMLFYDNKTPVNIAVSAEEISDSRQLLKLVNKKLDVTSSTSTKLVDYINASKRYNPPLNVKVATRLGHVKGYFIYPYQEVMKDSNIKLFSNDKGFQKLIDSFQSKGTLEGYSKKVFGQIKDLPMVMVMLYASLGSVLLREFGLQPFIVEISGSTSTGKTFTLNLVSSVWGTSDLITTWSSTQNSIESMASFLNSFPMFKDDTRNTHPKFVTSATYNFSSGESKSRSNINLTLNAKKEWRNILISTGESSIANMADEKAGVSARVVTLQDPPYPDNFDFTTLDKSFRENYGTLGLAFIKQYESKKDVYKNAFESYQRYFNQKGSNEIMQRLGRAFALLQVTGEVLNDIDGFEHDHFKIIEQAYDSMVKNNKTIDKPKQLLEELLQYLDANRNNIAGDGYSSVKNGDIKAIYKRDYLCILGQTVHDKLGHEMQTITGQWGKKGYLIKGEKDRLQKKVSHKNIKYRGFAINKEMLEELGFDFSNSHNPYSDY
>CP028468.1|AWQ23485.1|2015565_2015946_-|hypothetical-protein
MDKEQLKKYIYDYVKEYKEIPIYQLEDLFKEMNHDYIGRTSVTHDKDENIVFWSGWNKITMFALIELVKSEQLDLVYRGSFVMRYLLDGRVPNLPLAICYPEDGQQTDVPSWVPMVLRINKEEKIK
>CP028468.1|AWQ23484.1|2014927_2015569_-|pathogenicity-island-protein
MNIETIVNQFETRAGTLLRYYTGLLEHSKVQPCCFKLYNDPFDMAYVMMNGKLFGHVYIKDCKVRQSFELASPKHTEGLIRSIEGHYVGYELHDGKQLSISDMMASQLFEDEYFMYGLQTYAESNNSDVFEYLENGFDTDTLEGIQSSNTDVIANIEMLYQLATGINEPAPELVEGLRLVTEFVQDENATQEDYKALEHKLTELKSSYYSLNK
>CP028468.1|AWQ23494.1|2020669_2021344_+|XRE-family-transcriptional-regulator
MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRYDAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIENFDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSLSAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKSTTLHKEILQTDSRLSSDIFKEY
>CP028468.1|AWQ23495.1|2021357_2022530_+|site-specific-integrase
MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHAEMVERQLRNGDYIAPSTSTFKQVADDWISQYANEVKVSSVRAREKAINHAIERFNNKPIQTINKHEYQRFVNDISAQYSKNYVDSIIASTNMIFKYAYDMKLIRIMPSEGIKRPKKKISVEELEDTEIHKKFLEKDELFQFLEVAKNHHSPQNSFEVFCTLAYTGMRAGELLALKWSDIDFENNTINITKTYYNPNNNKKQFQILTPKTESSIGKISVDPHVIKLLKNYKTDVQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTDITNKQISTHSFRHTHCALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSKLMENVSKDLF
>CP028468.1|AWQ23496.1|2022598_2024215_-|molecular-chaperone-GroEL
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDSRVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>CP028468.1|AWQ23497.1|2024290_2024575_-|co-chaperone-GroES
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>CP028468.1|AWQ23498.1|2024751_2025495_+|CPBP-family-intramembrane-metalloprotease
MTRLWASLLTVIIYLLSQFLPAVIVNTTQFAQYSDLEQLKAGIYIQLVLFLIAATTIIFINFKIKDPTRLESEVKEPNKYIIPWALLGFALVMVYQFIVSIVLTQIYGGQQVSPNTEKIIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGSRIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRIAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>CP028468.1|AWQ23499.1|2025519_2026779_-|hypothetical-protein
MSYHWFKKMLLSTSILILSSSSLGLATHTVEAKDNLNGEKPTTNLNHNITSPSVNSEMNNNETGTPHKSNQTGNEETGSNSRDANPDSNNVKPDSNNQNPSPDSKPDSNNQNPSPNPKPNPDNPKPKPDPKPDPDKPKPNPDPKPDPDNPKPNPDPKPDPDKPKPNPDPKPDPDKPKPNPNPKPDPNKPNPNPSPDPDQPGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNTTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKHRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>CP028468.1|AWQ23500.1|2026975_2027602_+|nitroreductase-family-protein
MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSNEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK
>CP028468.1|AWQ23501.1|2027871_2028657_+|carbon-nitrogen-family-hydrolase
MKVQIYQLPIIFGDSSKNEIQITQWFEKNMNAEVDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNNQIFNTAFSVNKSGQLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSNGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESADILTVDLNLNEVEQQRENIPVFKSIKLDLYK
>CP028468.1|AWQ23502.1|2029062_2029830_-|AAA-family-ATPase
MNTNHQKLLNNFEILKLKKFKDYYPNYIELLSKNEKSLTEILIDLTEKEIEYQSELKFKRAVNSARFPKIKYLHDFDFMFQPSINQQEILTLKSMHFLEDSINICFLGNSGVGKTHLAISLGIEACKQNIKTRFYTFKELIDLLTVSDSKGIINKTLKQLSRIELLIIDEIGYTPITKEQADLFYQLMSLRYEWKSTIITTNIPFSSWGESFSNKIVSAAIIDRLVHHSKVFKITGESYRLKDYKTEKSLNIRQS
>CP028468.1|AWQ23503.1|2029841_2031077_-|IS21-family-transposase
MRHDIYEGVLFYIMKGIKPNYAELGRQYNCDPRTVKKYYEAGKENELERLKKRQQNKKASKLDPFKEIINKKIELGCTAMAIFKYIEKKGYEGKYTILREYCKNKKQNETKKATIRVETNPGIAAQVDWKEDMVMHDKFGRTYQFNIFLYVLHYSKMKYITLTWDRKQDTLFECLKDAFEYTEGVPKEIWFDNMRTVVDRPRTQYKKVVFNNLFYQFSKDANFEPIACRPYRPQTKGSVESLAKFVEQRLRPYDYEFYDAVELIGLVNDLCHELNHLEISQATEQRPIDVFNYEEKEHLNSFNAKLLDTYIENECIRIVSKESMINFRKGKYSVPTKYIGEEVQVIFNNSTDELLIYYDGELIRRHNLSERKFNYIVEDMSEILKSDVFKHKDDKEILTYIENSLLLYDEI

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Crispr_ID: CP028468_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028468_6

2152301-2152403

Orphan

Consensus_repeat	Method
AGCATCCAACTGTATTCCTCTATTTTTCAACTTTAGT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of CP028468_6

>merge|CP028468|6|2152301-2152403|CRISPRCasFinder
AGCATCCAACTGTATTCCTCTATTTTTCAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGCGCAGCATCCAACTGTGTTCCTCTATTTTTCAACTTTAGT

>CP028468|6|6|2152301-2152403|CRISPRCasFinder
AGCATCCAACTGTATTCCTCTATTTTTCAACTTTAGT	TGTTAGGGGCTCTTATGCAGTTGATGCGC
AGCATCCAACTGTGTTCCTCTATTTTTCAACTTTAGT

Protein	Signature genes	Signature genes Name	Protein_function
CP028468.1\|AWQ23622.1\|2154357_2155215_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
CP028468.1\|AWQ23613.1\|2145086_2146460_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
CP028468.1\|AWQ23619.1\|2151153_2152245_+\|transcriptional-regulator	unknown	unknown	unknown
CP028468.1\|AWQ23612.1\|2144217_2144631_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
CP028468.1\|AWQ23618.1\|2149907_2150888_+\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
CP028468.1\|AWQ23614.1\|2147133_2147364_-\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ23615.1\|2147394_2148333_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
CP028468.1\|AWQ23623.1\|2155282_2156065_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
CP028468.1\|AWQ23620.1\|2152759_2152864_-\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ23621.1\|2154144_2154237_+\|erm-Leader-peptide	unknown	unknown	unknown
CP028468.1\|AWQ23626.1\|2160355_2162488_+\|PRD-domain-containing-protein	unknown	unknown	gnl\|CDD\|226234
CP028468.1\|AWQ23610.1\|2142743_2143454_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
CP028468.1\|AWQ23625.1\|2158782_2160321_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
CP028468.1\|AWQ24279.1\|2153540_2153699_+\|integrase	unknown	unknown	unknown
CP028468.1\|AWQ23624.1\|2156296_2158102_-\|glutamine--fructose-6-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|234729
CP028468.1\|AWQ23617.1\|2149585_2149906_+\|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
CP028468.1\|AWQ23627.1\|2162499_2162934_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014
CP028468.1\|AWQ23616.1\|2148768_2149434_-\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
CP028468.1\|AWQ23611.1\|2143575_2144019_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
CP028468.1\|AWQ23628.1\|2162933_2164040_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031

Protein	Function_ID	Function_description	E-value
CP028468.1\|AWQ23622.1\|2154357_2155215_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	5.32332e-59
CP028468.1\|AWQ23613.1\|2145086_2146460_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.23955e-06
CP028468.1\|AWQ23623.1\|2155282_2156065_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	2.15146e-106
CP028468.1\|AWQ23612.1\|2144217_2144631_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.44732e-45
CP028468.1\|AWQ23618.1\|2149907_2150888_+\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.049e-108
CP028468.1\|AWQ23625.1\|2158782_2160321_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
CP028468.1\|AWQ23615.1\|2147394_2148333_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
CP028468.1\|AWQ23628.1\|2162933_2164040_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
CP028468.1\|AWQ23626.1\|2160355_2162488_+\|PRD-domain-containing-protein	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.54719e-67
CP028468.1\|AWQ23610.1\|2142743_2143454_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	1.82405e-156
CP028468.1\|AWQ23624.1\|2156296_2158102_-\|glutamine--fructose-6-phosphate-aminotransferase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP028468.1\|AWQ23617.1\|2149585_2149906_+\|ArsR-family-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.83702e-17
CP028468.1\|AWQ23627.1\|2162499_2162934_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
CP028468.1\|AWQ23616.1\|2148768_2149434_-\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	9.50195e-47
CP028468.1\|AWQ23611.1\|2143575_2144019_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	5.87929e-68

>CP028468.1|AWQ23619.1|2151153_2152245_+|transcriptional-regulator
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDKKVVTEPKNTKVENDKVATSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>CP028468.1|AWQ23618.1|2149907_2150888_+|cation-transporter
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>CP028468.1|AWQ23617.1|2149585_2149906_+|ArsR-family-transcriptional-regulator
MSEQYSEIHTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>CP028468.1|AWQ23616.1|2148768_2149434_-|NAD(P)-dependent-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNYQEFQIISGEQDIKDALTQFEIEKD
>CP028468.1|AWQ23615.1|2147394_2148333_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>CP028468.1|AWQ23614.1|2147133_2147364_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>CP028468.1|AWQ23613.1|2145086_2146460_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYEAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>CP028468.1|AWQ23612.1|2144217_2144631_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYRFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIQLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>CP028468.1|AWQ23611.1|2143575_2144019_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLEKAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>CP028468.1|AWQ23610.1|2142743_2143454_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNAAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>CP028468.1|AWQ23620.1|2152759_2152864_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK
>CP028468.1|AWQ24279.1|2153540_2153699_+|integrase
MRKSSDALFNLLTQSFELIEGVHNELVTDNLKTVMYKPRKERTNGRINRRFK
>CP028468.1|AWQ23621.1|2154144_2154237_+|erm-Leader-peptide
MTFGSIVAILCALFVIFFIPYMEKKDKKKK
>CP028468.1|AWQ23622.1|2154357_2155215_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINRLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQIINLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQDETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>CP028468.1|AWQ23623.1|2155282_2156065_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGEMPGKVGYSAETVRQHIGFVSHSLLEKFQDGERVIDVVISGAFKSIGVYQDIDDEVRNEAHQLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>CP028468.1|AWQ23624.1|2156296_2158102_-|glutamine--fructose-6-phosphate-aminotransferase
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>CP028468.1|AWQ23625.1|2158782_2160321_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPIMKFIMHILSVAVESLVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVATLIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>CP028468.1|AWQ23626.1|2160355_2162488_+|PRD-domain-containing-protein
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVESYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQLQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLDQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDTPYLMVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMNDKDDVHVETKDIDGNTSFENEQTSNLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDAIKDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRSKFLERIKKQFI
>CP028468.1|AWQ23627.1|2162499_2162934_+|mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>CP028468.1|AWQ23628.1|2162933_2164040_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFASFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTGDQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS

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Crispr_ID: CP028468_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028468_7

2232553-2232677

Orphan

Consensus_repeat	Method
CCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP028468_7

>merge|CP028468|7|2232553-2232677|CRISPRCasFinder
CCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCAATGATTTCCCATGATTTTTTAGTATTTTCTTTTGAGTTACTCGAAAATTATCCTCTTTACTCGAAAGCTCACAAAACGCTTGATATCA

>CP028468|7|7|2232553-2232677|CRISPRCasFinder
CCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCA	ATGATTTCCCATGATTTTTTAGTATTTTCTTTTGAGTTACTCGAAAATTAT
CCTCTTTACTCGAAAGCTCACAAAACGCTTGATATCA

Protein	Signature genes	Signature genes Name	Protein_function
CP028468.1\|AWQ23687.1\|2238357_2239302_-\|DNA-directed-RNA-polymerase-subunit-alpha	unknown	unknown	gnl\|CDD\|235359
CP028468.1\|AWQ23670.1\|2220410_2222837_+\|hyaluronate-lyase	unknown	unknown	gnl\|CDD\|238517
CP028468.1\|AWQ23671.1\|2222896_2223751_-\|M23-family-peptidase	unknown	unknown	gnl\|CDD\|223810
CP028468.1\|AWQ23686.1\|2237972_2238341_-\|50S-ribosomal-protein-L17	unknown	unknown	gnl\|CDD\|235522
CP028468.1\|AWQ23678.1\|2231475_2231658_-\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ23682.1\|2234164_2234968_-\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
CP028468.1\|AWQ23677.1\|2229316_2230981_-\|acetolactate-synthase-AlsS	unknown	unknown	gnl\|CDD\|236312
CP028468.1\|AWQ23673.1\|2224912_2226298_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|340855
CP028468.1\|AWQ23688.1\|2239376_2239766_-\|30S-ribosomal-protein-S11	unknown	unknown	gnl\|CDD\|180007
CP028468.1\|AWQ23676.1\|2228575_2229280_-\|acetolactate-decarboxylase	unknown	unknown	gnl\|CDD\|226058
CP028468.1\|AWQ23681.1\|2233487_2233925_-\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
CP028468.1\|AWQ23684.1\|2235768_2236629_-\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|184205
CP028468.1\|AWQ23672.1\|2224624_2224903_+\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ23679.1\|2232307_2232487_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236623
CP028468.1\|AWQ23685.1\|2236625_2237435_-\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|184207
CP028468.1\|AWQ23675.1\|2227771_2228197_+\|MAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|367591
CP028468.1\|AWQ23683.1\|2234972_2235779_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
CP028468.1\|AWQ23680.1\|2233075_2233474_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
CP028468.1\|AWQ23674.1\|2226661_2227477_-\|hydrolase	unknown	unknown	gnl\|CDD\|319792
CP028468.1\|AWQ23689.1\|2239789_2240155_-\|30S-ribosomal-protein-S13	unknown	unknown	gnl\|CDD\|235358

Protein	Function_ID	Function_description	E-value
CP028468.1\|AWQ23687.1\|2238357_2239302_-\|DNA-directed-RNA-polymerase-subunit-alpha	gnl\|CDD\|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	1.89947e-175
CP028468.1\|AWQ23670.1\|2220410_2222837_+\|hyaluronate-lyase	gnl\|CDD\|238517	cd01083, GAG_Lyase, Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.	0
CP028468.1\|AWQ23671.1\|2222896_2223751_-\|M23-family-peptidase	gnl\|CDD\|223810	COG0739, NlpD, Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane].	7.61272e-24
CP028468.1\|AWQ23682.1\|2234164_2234968_-\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	5.95917e-120
CP028468.1\|AWQ23681.1\|2233487_2233925_-\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	2.37368e-100
CP028468.1\|AWQ23673.1\|2224912_2226298_+\|hypothetical-protein	gnl\|CDD\|340855	cd04949, GT4_GtfA-like, accessory Sec system glycosyltransferase GtfA and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.	3.23915e-52
CP028468.1\|AWQ23688.1\|2239376_2239766_-\|30S-ribosomal-protein-S11	gnl\|CDD\|180007	PRK05309, PRK05309, 30S ribosomal protein S11; Validated.	2.01588e-89
CP028468.1\|AWQ23677.1\|2229316_2230981_-\|acetolactate-synthase-AlsS	gnl\|CDD\|236312	PRK08617, PRK08617, acetolactate synthase AlsS.	0
CP028468.1\|AWQ23686.1\|2237972_2238341_-\|50S-ribosomal-protein-L17	gnl\|CDD\|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	2.70058e-62
CP028468.1\|AWQ23684.1\|2235768_2236629_-\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|184205	PRK13646, cbiO, energy-coupling factor transporter ATPase.	0
CP028468.1\|AWQ23680.1\|2233075_2233474_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	4.27268e-81
CP028468.1\|AWQ23679.1\|2232307_2232487_-\|hypothetical-protein	gnl\|CDD\|236623	PRK09775, PRK09775, type II toxin-antitoxin system HipA family toxin YjjJ.	0.0004492
CP028468.1\|AWQ23675.1\|2227771_2228197_+\|MAP-domain-containing-protein	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	2.66977e-34
CP028468.1\|AWQ23683.1\|2234972_2235779_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	7.16976e-49
CP028468.1\|AWQ23685.1\|2236625_2237435_-\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|184207	PRK13648, cbiO, cobalt transporter ATP-binding subunit; Provisional.	0
CP028468.1\|AWQ23674.1\|2226661_2227477_-\|hydrolase	gnl\|CDD\|319792	cd02605, HAD_SPP, sucrose-phosphatase, similar to Synechocystis sp PCC 6803 SPP. Sucrose-phosphatase (SPP; EC 3.1.3.24) catalyzes the dephosphorylation of sucrose-6(F)-phosphate (Suc6P)-the final step in the pathway of sucrose biosynthesis in plants and cyanobacteria. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	5.0464e-100
CP028468.1\|AWQ23676.1\|2228575_2229280_-\|acetolactate-decarboxylase	gnl\|CDD\|226058	COG3527, AlsD, Alpha-acetolactate decarboxylase [Secondary metabolites biosynthesis, transport, and catabolism].	9.58959e-119
CP028468.1\|AWQ23689.1\|2239789_2240155_-\|30S-ribosomal-protein-S13	gnl\|CDD\|235358	PRK05179, rpsM, 30S ribosomal protein S13; Validated.	2.16257e-78

>CP028468.1|AWQ23679.1|2232307_2232487_-|hypothetical-protein
MTEIVEFLSDGKLASRLEIQETMGLQKSYTSELIAELKKLEIIGSEGRGPGTRYYLIRD
>CP028468.1|AWQ23678.1|2231475_2231658_-|hypothetical-protein
MKDSIFWKKAFIPVYFIVAMLVFLLFRFYIKTDNFSMYLMIIFLICLGTASIIYNYKNNR
>CP028468.1|AWQ23677.1|2229316_2230981_-|acetolactate-synthase-AlsS
MTDKKYTAADMVIDTLKNNGVEYVFGIPGAKIDYLFNALIDDGPELIVTRHEQNAAMMAQGIGRLTGKPGVVLVTSGPGVSNLTTGLLTATSEGDPVLALGGQVKRNDLLRLTHQSIDNAALLKYSSKYSEEVQDPESLSEVMTNAIRIATSGKNGASFISIPQDVISSPAESKAISLCQKPNLGVPSEQDINDVIEAIKNASFPVLLAGMRSSSADETNAIRKLVERTNLPVVETFQGAGLISRELENHFFGRVGLFRNQVGDELLRKSDLVVTIGYDPIEYEASNWNKELDTQIINIDEVQAEITNYMQPKKELIGNIAKTIEMISDKVDEPFINQQHLDELEQLRAHIDQETGIKATHEEGILHPVEIIESMQKVLTDETTVTVDVGSHYIWMARNFRSYNPRHLLFSNGMQTLGVALPWAISAALVRPNTQVVSVAGDGGFLFSSQDLETAVRKNLNIIQLIWNDGKYNMVEFQEEMKYKRSSGVDFGPVDFVKYAESFGAKGLRVTNQEELEAAIKEGYETDGPVLIDIPVNYKDNIKLSTNMLPDVFN
>CP028468.1|AWQ23676.1|2228575_2229280_-|acetolactate-decarboxylase
MASVLYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNGEVIFLDGKAYHANEHKEFVELKGDELTPYATVTKFVADTSYETKDKSSEAVFAEIKEKMLSENLFSAVKISGLFKKMHVRMMPAQEPPYTRLIDSARRQPEQTETYVKGSVVGFFTPELFHGIGSAGFHVHFANDDRNFGGHVLDFEVEDVKVEIQNIETFEQHFPIHDEDFTNANIDYKDISDEIREAE
>CP028468.1|AWQ23675.1|2227771_2228197_+|MAP-domain-containing-protein
MKLKSFVTATLALGLLSTVGAALPSHEASADSNNGYKEMTMDGYHTVPYTISVDGITALHRTYFVFPENKKVLYQEIDSKVKNELASQRGVTTEKINNAQTATYTLTLNDGNKKVVNLKKNDDAKNSIDPSTIKQIQIVVK
>CP028468.1|AWQ23674.1|2226661_2227477_-|hydrolase
MSKRLLLFDFDETYFKHNTNEEDLSHLREMEKLLEKLTNNNEVITAVLTGSTFQSVMDKMDQVNMTFKPLHIFSDLSSKMFTWNNGEYVESETYKKKVLSEPFLFEDIEDILRHISAQYNVEFIPQRAFEGNETHYNFYFHSTGNHNNDRRILEALVRYANDQNYTARFSRSNPLAGDPENAYDIDFTPSNAGKLYATQFLMKKYNIPVKSILGFGDSGNDEAYLSYLEHAYLMSNSRDEALKQKFRLTKYPYYQGITLHVKEFVEGKYDY
>CP028468.1|AWQ23673.1|2224912_2226298_+|hypothetical-protein
MTTYMLMYSIPEKAGGITSVMLNRSKLLAEKGYSCALLTLDDKNYDPLRAKLTNSGRLHKQVKIVNLYEELKMLYDVENTEIENKNMQTFEKLNLLNQEGFYIQKDEYEEKKYARYFKDNHYIMYKKWINGQLSHIDYFQNRKRFKRHVFQNKILRKEITFNDKNKMSEVKYLSNDGFCYLSYWYGDNENIVNIFYFDKNSKEVLNFKNNKAFHSYWLDKNLTSNDVLILDGIGTYHKVENMQNNDIKKIFTIHTNHFMSPYSYGAEIKPEFRNMLLNLKELDTLVVLTKEQKDDIIKQFGDYNNIKVIPNAISFEENLTQNIREKNSIIVLQRFVAMKNITHIISAINIVRKKVKDVKLHIYGTGTQKENYTKLIKKLKLQDNVFIHDYAFDIRALYTKTSLSVLTSDYEGLPMSLLEAMSYGVPVISYPINYGPKSIIQNNINGIITKKKDNINELAKK
>CP028468.1|AWQ23672.1|2224624_2224903_+|hypothetical-protein
MTLNEYNYNNELILKLNKIEVQKNNEKISEVFKDYEILKPKIVFNGSNPYLALNHIIVAEIENYSSLETFSKIYVDEDYYYNYGELIIKCKK
>CP028468.1|AWQ23671.1|2222896_2223751_-|M23-family-peptidase
MNKTNFGDYLNKSKSRKIYKIFDQNLKREFSYWHFRKLFKSYTRQSDVHELKVCTQNDGTMEQIWIDKANQFGVAVTWKDNSIIGFVMRPLINYDAIKNETTLKYAVPTTDCYEVFWGGDNELYNYHYLYPHQRYAIDLVIKENHKTYKNKGKVNTDYFYFGKDIIAPANGTVEKVANGVQDNSIGSTNESQFLGNYIVIKHAENEYSLIAHLQQYSIIVNEGQNVKYGDIIGKVGNSGNSTEPHIHFQVMNDKNIEACTSLKIRFINNRELIKGDVVCGLQGE
>CP028468.1|AWQ23670.1|2220410_2222837_+|hyaluronate-lyase
MTYRMKKWQKISTITLLMAGVITFNDSEFRSVDKHQIAVADTNVQTTDYEKLRNTWLNVNYGYNQYDENNDAMKKKFEATEKEATNLLSSMKTESDRKYLWENSKDLDTKSADMTRTYRNIEKIAEAMKHKNTKLNTPDNKNKVKDALEWLHKNAYGKEPTDKVKELTENFKNKTSRNTNLNWWDYEIGTPRALTNTLILLNGDISSDEKKKYTAPIKTFAPESDKILSSVGQPEQAKGGNLVDIAKVKLLESIIEEDTTMMKESIDAFNKVFTYVQSNATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPMIKETSFKDSNQNDTTLKSWIDEGFMPLIYKGEMMDLSRGRAISRENETSHSVSATVMKSLLRLSDAMDDSTKAKYKQIVKTSVKSDSSYKQNDYLSSYSDISKMKSLMEDSTISTNDLTQQLKIYNDMDRVTYHNKGLDFAFGLSMTSKNVARYESINNENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTIENEEPKGTDVKKSSKTFVGGTKFDDQHASIGMDFENQDKTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKTNGYTLYTDDKQTTASDNQDTNSVFLESTNKPKNNIGYHFLNKSKITVKKESHTGKWSDINKSQKSEDKTDEYYEVTQKHSDKDNKYGYVLYPGITKDNFKSKASQVTVVKQDDDFHVVKDNESVWAGVNYSDSAKTFEINGTKVEVKAKGMFILKKKNDKTYECSFYNPESTNPASDIESKISMTGYSITNKDTSTTNESGVRFELTK
>CP028468.1|AWQ23680.1|2233075_2233474_-|30S-ribosomal-protein-S9
MTLAQVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVRKYLPFESLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGLLTRDPRMKERKKPGLKAARRSPQFSKR
>CP028468.1|AWQ23681.1|2233487_2233925_-|50S-ribosomal-protein-L13
MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKATYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
>CP028468.1|AWQ23682.1|2234164_2234968_-|tRNA-pseudouridine(38-40)-synthase-TruA
MRILVEIAYQGNNFLGFQIQQNGRTVQQQFEKLLQRMHKRHVRIHPSSRTDRGVHAIQQYFHFDTELNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFHCRYDCVGKRYRYKVYQAQHRDPFQSGLKTFIPETLDLDKMNRAAQQFIGTHDFTGFCSQKTEVESKVRTLYQSEIVKTDDGFDYIVTGSGFLYNMVRVLVAFLIEVGKGRHEVSDVPKLLESKNRKNVPFTAPAEGLYLEKIYLDENELLKDFGNDIKIHRKKSLQND
>CP028468.1|AWQ23683.1|2234972_2235779_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MKNKLIIGRYLPINSFVHHLDPRAKLMFVFLFIILIFFCHSPLTYLWVFALILFFMRLAKIQLWFLIKGLTPIFFFLIFTLMMHIFLTKGGYVLVEWHGITIETNGILEGLYISLRLIGIVMIATIMTLSTSPIDLTDAFERLLAPLKMFKLPVHQLSMIMSIALRFIPTLMDELDKIILAQKSRGSEISSGNIATRIKSFIPLLVPLFISAFQRAEELAVAMEVRGYDANVQRTSYRQLKWQLRDTLSLIMIIPFAIILFVLKYSGV
>CP028468.1|AWQ23684.1|2235768_2236629_-|energy-coupling-factor-transporter-ATPase
MTIRFDNVSYTYQKGTPYQHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPVRKRIGMVFQFPESQLFEDTVEREMIFGPKNFKMNLDEAKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVVDEPTAGLDPQSKRQVMRLLKSLQTDENKAIILISHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKEKLADWHIGLPEIVQLQYDFEQKHQTKLKDIALTEEAFVSLYKEWQHEK
>CP028468.1|AWQ23685.1|2236625_2237435_-|energy-coupling-factor-transporter-ATPase
MEDKNSVIVFKNVSFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKDIGIVFQNPDNQFVGSIVKYDVAFGLENHAVPHDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIASVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAMEADHVIVMNKGTVYKEGTAIEIFDHAEELTTIGLDLPFPIKINQMLGYQTSFLTYEGLVDQL
>CP028468.1|AWQ23686.1|2237972_2238341_-|50S-ribosomal-protein-L17
MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV
>CP028468.1|AWQ23687.1|2238357_2239302_-|DNA-directed-RNA-polymerase-subunit-alpha
MIEIEKPRIETIEISEDAKFGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVKYIEIEGVLHEFSAVDNVVEDVSTIIMNIKQLALKIYSEEDKTLEIDVRDEGEVTASDITHDSDVEILNPELKIATVSKGGHLKIRLVANKGRGYALAEQNNTSDLPIGVIPVDSLYSPVERVNYTVENTRVGQSSDFDKLTLDVWTNGSITPQESVSLAAKIMTEHLNIFVGLTDEAQNAEIMIEKEEDQKEKVLEMSIEELDLSVRSYNCLKRAGINSVQELADKSEADMMKVRNLGRKSLEEVKYKLEDLGLGLRKED
>CP028468.1|AWQ23688.1|2239376_2239766_-|30S-ribosomal-protein-S11
MARKQVSRKRRVKKNIENGVAHIRSTFNNTIVTITDEFGNALSWSSAGALGFKGSKKSTPFAAQMASETASKSAMEHGLKTVEVTVKGPGPGRESAIRALQSAGLEVTAIRDVTPVPHNGCRPPKRRRV
>CP028468.1|AWQ23689.1|2239789_2240155_-|30S-ribosomal-protein-S13
MARIAGVDIPREKRVVISLTYIYGIGTSTAQKILEEANVSADTRVKDLTDDELGRIREVVDGYKVEGDLRRETNLNIKRLMEISSYRGIRHRRGLPVRGQKTKNNARTRKGPVKTVANKKK

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Crispr_ID: CP028468_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028468_8

2489187-2489270

Orphan

Consensus_repeat	Method
ACAGACAATGCAAGTTGGGGTGTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP028468_8

>merge|CP028468|8|2489187-2489270|CRISPRCasFinder
ACAGACAATGCAAGTTGGGGTGTGGGCCCCAACAAAGAGAAATTGGATTCCCAATTTCCACAGACAATGCAAGTTGGGGTGGGA

>CP028468|8|8|2489187-2489270|CRISPRCasFinder
ACAGACAATGCAAGTTGGGGTGTGG	GCCCCAACAAAGAGAAATTGGATTCCCAATTTCC
ACAGACAATGCAAGTTGGGGTGGGA

Protein	Signature genes	Signature genes Name	Protein_function
CP028468.1\|AWQ23939.1\|2481686_2482463_-\|iron-export-ABC-transporter-permease-subunit-FetB	unknown	unknown	gnl\|CDD\|223467
CP028468.1\|AWQ23948.1\|2489386_2490580_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
CP028468.1\|AWQ23946.1\|2486399_2487977_-\|FMN-binding-glutamate-synthase-family-protein	unknown	unknown	gnl\|CDD\|223147
CP028468.1\|AWQ23954.1\|2495700_2497002_-\|staphylopine-biosynthesis-dehydrogenase	unknown	unknown	gnl\|CDD\|226839
CP028468.1\|AWQ23952.1\|2493011_2493947_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
CP028468.1\|AWQ23950.1\|2491333_2492149_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
CP028468.1\|AWQ23941.1\|2483463_2484540_-\|M42-family-peptidase	unknown	unknown	gnl\|CDD\|349906
CP028468.1\|AWQ23956.1\|2497823_2498645_-\|histidine-racemase-CntK	unknown	unknown	gnl\|CDD\|223331
CP028468.1\|AWQ23953.1\|2493959_2495558_-\|staphylopine-dependent-metal-ABC-transporter-substrate-binding-protein-CntA	unknown	unknown	gnl\|CDD\|274072
CP028468.1\|AWQ23942.1\|2484894_2485161_-\|Txe/YoeB-family-addiction-module-toxin	unknown	unknown	gnl\|CDD\|226600
CP028468.1\|AWQ23949.1\|2490591_2491341_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224049
CP028468.1\|AWQ23957.1\|2498731_2498926_+\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ23947.1\|2488171_2488921_+\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ23944.1\|2485502_2485718_-\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ23940.1\|2482455_2483118_-\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226970
CP028468.1\|AWQ23945.1\|2485776_2486232_+\|DUF1307-domain-containing-protein	unknown	unknown	gnl\|CDD\|227145
CP028468.1\|AWQ23938.1\|2480105_2481293_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
CP028468.1\|AWQ23951.1\|2492145_2493015_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
CP028468.1\|AWQ23943.1\|2485160_2485418_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|225072
CP028468.1\|AWQ23955.1\|2496994_2497813_-\|staphylopine-biosynthesis-enzyme-CntL	unknown	unknown	gnl\|CDD\|176222

Protein	Function_ID	Function_description	E-value
CP028468.1\|AWQ23939.1\|2481686_2482463_-\|iron-export-ABC-transporter-permease-subunit-FetB	gnl\|CDD\|223467	COG0390, COG0390, ABC-type uncharacterized transport system, permease component [General function prediction only].	5.19402e-101
CP028468.1\|AWQ23948.1\|2489386_2490580_-\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.36995e-79
CP028468.1\|AWQ23946.1\|2486399_2487977_-\|FMN-binding-glutamate-synthase-family-protein	gnl\|CDD\|223147	COG0069, GltB, Glutamate synthase domain 2 [Amino acid transport and metabolism].	5.04566e-175
CP028468.1\|AWQ23954.1\|2495700_2497002_-\|staphylopine-biosynthesis-dehydrogenase	gnl\|CDD\|226839	COG4408, COG4408, Uncharacterized protein conserved in bacteria [Function unknown].	0
CP028468.1\|AWQ23952.1\|2493011_2493947_-\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.85614e-99
CP028468.1\|AWQ23950.1\|2491333_2492149_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.18808e-119
CP028468.1\|AWQ23941.1\|2483463_2484540_-\|M42-family-peptidase	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	3.30693e-171
CP028468.1\|AWQ23956.1\|2497823_2498645_-\|histidine-racemase-CntK	gnl\|CDD\|223331	COG0253, DapF, Diaminopimelate epimerase [Amino acid transport and metabolism].	1.05454e-73
CP028468.1\|AWQ23953.1\|2493959_2495558_-\|staphylopine-dependent-metal-ABC-transporter-substrate-binding-protein-CntA	gnl\|CDD\|274072	TIGR02294, Nickel-binding_periplasmic_protein, nickel ABC transporter, nickel/metallophore periplasmic binding protein. Members of this family are periplasmic nickel-binding proteins of nickel ABC transporters. Most appear to be lipoproteins. This protein was previously (circa 2003) thought to mediate binding to nickel through water molecules, but is now thought to involve a chelating organic molecule, perhaps butane-1,2,4-tricarboxylate, acting as a metallophore. [Transport and binding proteins, Cations and iron carrying compounds].	0
CP028468.1\|AWQ23942.1\|2484894_2485161_-\|Txe/YoeB-family-addiction-module-toxin	gnl\|CDD\|226600	COG4115, COG4115, Uncharacterized protein conserved in bacteria [Function unknown].	3.49994e-30
CP028468.1\|AWQ23949.1\|2490591_2491341_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.93009e-106
CP028468.1\|AWQ23940.1\|2482455_2483118_-\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|226970	COG4619, COG4619, ABC-type uncharacterized transport system, ATPase component [General function prediction only].	1.21101e-118
CP028468.1\|AWQ23945.1\|2485776_2486232_+\|DUF1307-domain-containing-protein	gnl\|CDD\|227145	COG4808, COG4808, Uncharacterized protein conserved in bacteria [Function unknown].	5.59595e-52
CP028468.1\|AWQ23938.1\|2480105_2481293_-\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.60636e-89
CP028468.1\|AWQ23951.1\|2492145_2493015_-\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.01187e-84
CP028468.1\|AWQ23943.1\|2485160_2485418_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|225072	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	1.00456e-14
CP028468.1\|AWQ23955.1\|2496994_2497813_-\|staphylopine-biosynthesis-enzyme-CntL	gnl\|CDD\|176222	cd08261, Zn_ADH7, Alcohol dehydrogenases of the MDR family. This group contains members identified as related to zinc-dependent alcohol dehydrogenase and other members of the MDR family. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group includes various activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0.000103671

>CP028468.1|AWQ23947.1|2488171_2488921_+|hypothetical-protein
MSNTNKHYIEEEYATEQSRFFKRDIGFIFLYIFLVNILPIIIVFLTFGLVAIFTQQAPWDFSFPISMNISYLLAVILSLAIFRRMHEDAFIPMIRSQIVASTKYKWHILISFTLSIVLFLLLNHFEIFALNVDSFTVFDIYPLIREYGSISLIAIFSLTIILNTLICQLIFRHILIQELSRLIPLKITIVLSVILETLYYYPYINTWWEFIPALILASSATYLYLKSNRNFMVSYFYQLAVILVLHIFM
>CP028468.1|AWQ23946.1|2486399_2487977_-|FMN-binding-glutamate-synthase-family-protein
MTFLTVMQFIVNIIIIGFLLTVIVIGLIWLIKDKRQSQHSVLRNYPLLARIRYISEKMGPELRQYLFSGDNEGKPFSRNDYKNIVLAGKYNSRMTSFGTTKDYQDGFYIQNTMFPMQRNEISVDNTTLLSTFIYKIANERLFSREEYRVPTKIDPYYLSDDHAIKLGEHLKYPFILKRIVGQSGMSYGALGKNAITALSKGLAKAGTWMNTGEGGLSEYHLKGNGDIIFQIGPGLFGVRDKEGNFSEGLFKEVAQLSNVRAFELKLAQGAKTRGGHMEAEKVNEEIAKIRNVEPYKTINSPNRYEFIHNAEDLIRFVDQLQQLGQKPVGFKIVVSKVSEIETLVRTMVELDKYPSFITIDGGEGGTGATFQELQDGVGLPLFTALPIVSGMLEKYGIRDKVKLAASGKLVTPDKIAIALGLGADFVNIARGMMISVGCIMSQQCHMNTCPVGVATTDAKKEKALIVGEKQYRVTNYVTSLHEGLFNIAAAVGVSSPTEITADHIVYRKIDGELQTIHDYKLKLIS
>CP028468.1|AWQ23945.1|2485776_2486232_+|DUF1307-domain-containing-protein
MKKLCSLIVVALVCIIALSACGKEQTKTYEGDVSGKHVLTSITYKDDKVLKQSTINTIKYDDLGMDKDEAKKLFAKSESIFKDLKGVKYKVDYKDKKAIEHLDIDYTEVDMKKLNKRLGVSTKENKDISFEKLEKQLKHRGLKEKDKMDDK
>CP028468.1|AWQ23944.1|2485502_2485718_-|hypothetical-protein
MMLFKNLNFVIFFGDMRFLKRISHKVFKIIKSENDKAVGNVVCSTADFFLSIIDGMLEEKNKSLCTIAYRY
>CP028468.1|AWQ23943.1|2485160_2485418_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MIITSPTEARKDFYQLLKNVNNNHEPIYISGNNAENNAVIIGLEDWKSIQETIYLESTGTMDKVREREKDNSGTTNIDDIDWDNL
>CP028468.1|AWQ23942.1|2484894_2485161_-|Txe/YoeB-family-addiction-module-toxin
MSNYTVKIKNSAKSDLKKIKHSYLKKSFLEIVETLKNDPYKITQSFEKLEPKYLERYSRRINHQHRVVYTVDDRNKEVLILSAWSHYD
>CP028468.1|AWQ23941.1|2483463_2484540_-|M42-family-peptidase
MNQSVKLLKHLTDVNGIAGYEMQVKEAMRNYIEPVSDQIIEDNLGGIFGKKNAENGQYSIMISGHMDEVGFMVTKIDKHGFISFTPVGGWWNQVMLSQKVTITTDSGKEIRGIIGSKPPHVLTPEERKKPMEIKNMFIDIGVSSKGEAEEAGVEVGNMVTPYSEFEVLANNKYLTAKAFDNRYGCALAIEVLQRLKDENIGINLYSGATVQEEVGLRGAKVAANTIKPDLAIAVDVGIAYDTPGMSGQTSDSKLGGGPVVIMMDATSIAHQGLRKHIKDVAKKHNIEVQWDTTPGGGTDAGSIHVANEGIPTMTIGVTLRYMHSNVSVLNVDDYENSIRLVTEIVRSLNDETYKNIMW
>CP028468.1|AWQ23940.1|2482455_2483118_-|methionine-ABC-transporter-ATP-binding-protein
MLLEIKDLVYEASDRVILNHINLKVDKGETIAIIGPSGSGKSTFQKIICNLISPTSGTLYFKDKPYDDYEPEILRRHISYLMQQSDLFGETIEDNMIFPSLARNDKFDKKRAKQLIKDVGLGHYQLSSKIEHMSGGERQRIAIARQLMYTPDILLLDESTSALDIHNKEKIENIIFKLADQGVAIMWITHSDDQSMRHFQKRITIVDGQISNIEELNQHE
>CP028468.1|AWQ23939.1|2481686_2482463_-|iron-export-ABC-transporter-permease-subunit-FetB
MSNTALGLTALLLVIPIIISYKEGLHIIKDLIVATLRAVVQLIILGFLLHYIFKINDKWLLVLCVFVIIVNASWNTISRSSPVMHHVFWISFVAIFVGTALPLAGTIATGAIQFTANEVIPIGGMLANNGLIAINLAYQNLDRAFVQDGTNIESKLSLAATPKLASKGAIRESIRLAIVPTIDSVKTYGLVSIPGMMTGLIIGGVPPLQAIKFQLLVVFIHTTATIMSALIATYLSYGQFFNARHQLVARNTDVKSES
>CP028468.1|AWQ23938.1|2480105_2481293_-|MFS-transporter
MSIMRLFTFILSIFIVGMVEMMVAGIMNLMSQDLHVSEAVVGQLVTMYALTFAICGPILVKLTNRFSSRPVLLWTLLIFIIGNGIIAVAPNFSILVVGRIISSAAAALIIVKVLAITAMLSAPKNRGKMIGLVYTGFSGANVFGVPIGTVIGDLVGWRYTFLFLIIVSIIVGFLMMSYLPKDQEIQRGSVNHEAPSHENHVTSKILRPAEVAKYLIITFLVLIANSVTFVFINPLILSNGHDMSFVSLALLVNGIAGVIGTSLGGIFSDKITSKRWLMISVSIFIVMMLLMNLILPGSGLLLAGLFIWNIMQWSTNPAVQSGVIQHVEGDTSQVMSWNMSSLNAGIGVGGIIGGLVMTHVSVQAITYTSAIIGALGLIVVLTLKNNHYAKTFKSS
>CP028468.1|AWQ23948.1|2489386_2490580_-|MFS-transporter
MKGAMAWPFLRLYILTLMFFSANAILNVFIPLRGHDLGATNTVIGIVMGAYMLTAMVFRPWAGQIIARVGPIKVLRIILIINAIALIIYGFTGLEGYFVARVMQGVCTAFFSMSLQLGIIDALPEEHRSEGVSLYSLFSTIPNLIGPLVAVGIWNANNISLFAIVIIFIALTTTFFGYRVTFAEQEPDTSDKIEKMPFNAVTVFAQFFKNKELLNSGIIMIVASIVFGAVSTFVPLYTVSLGFANAGIFLTIQAIAVVAARFYLRKYIPSDGMWHPKYMVSVLSLLVIASFVVAFGPQVGAIIFYGSAILIGMTQAMVYPTLTSYLSFVLPKVGRNMLLGLFIACADLGISLGGALMGPISDLVGFKWMYLICGMLVIVIMIMSLLKKPTPRPANSL
>CP028468.1|AWQ23949.1|2490591_2491341_-|ABC-transporter-ATP-binding-protein
MIKIKDVEKSYQSAHVFKRRRTPIVKGVSFECPIGATIAIIGESGSGKSTLSRMILGIEKPDKGCVTLNDHPMHKKKVRRHQIGAVFQDYTSSLHPFQTVREILFEVMCQCDGQPKDVMEVQAITLLEEVGLSKAYMDKYPNMLSGGEAQRVAIARAICINPKYILFDEAISSLDMSIQTQILDLLIHLRETRQLSYIFITHDIQAATYLCDQLIIFKNGKIEEQIPTSALHKSDNAYTRELIEKQLSF
>CP028468.1|AWQ23950.1|2491333_2492149_-|ABC-transporter-ATP-binding-protein
MTLLTVKHLTITDTWTDQPLVSDVNFTLTKGETLGVIGESGSGKSITCKSIIGLNPERLGVTGDITFDGKPMLSLSEAQLKKYRGKDIAMVMQQGSRAFDPSTTVGKQMFETMKVHTSMSTQEIEKTLIEYMDYLSLKDPKRILKSYPYMLSGGMLQRLMIALALALKPKLIIADEPTTALDTITQYDVLEAFIDIKKHFDCAMIFISHDLTVINKIADRVVVMKNGQLIEHGTRESVLHHPKHVYTKYLLSTKKKINDHFKHVMRGDVHD
>CP028468.1|AWQ23951.1|2492145_2493015_-|ABC-transporter-permease
MIILKRLLQDKGAVVALGIIVLYVFLGLAAPLVTFYDPNHIDTANKFAGMSFQHLLGTDHLGRDILTRLIYAIRPSLLYVFVALFVSVLIGSILGFLSGYFQGFVDALIMRACDVMLAFPSYVVTLALIALFGMGAENIIMAFILTRWAWFCRVIRTSVMQYTASDHVRFAKTIGMNDMKIIHKHIMPLTLADIAIISSSSMCSMILQISGFSFLGLGVKAPTAEWGMMLNEARKVMFTHPEMMFAPGIAIVIIVMAFNFLSDALQIAIDPRISSKDKLRSVKKGVVQS
>CP028468.1|AWQ23952.1|2493011_2493947_-|ABC-transporter-permease
MFKFILKRIALMFPLVIVVSFMTFLLTYITNENPAVTILHAQGTPNVTPELIAETNEKYGFNDPLLIQYKNWLLEAMQFNFGTSYITGDPVAERIGPAFMNTLKLTIISSVMVMITSIILGVVSALKRGKFTDRAIRSVAFFLTALPSYWIASILIIYVSVKLNILPTSGLTGPESYILPVIVITIAYAGIYFRNVRRSMVEQLNEDYVLYLRASGVKSITLMLHVLRNALQVAVSIFCMSIPMIMGGLVVIEYIFAWPGLGQLSLKAILEHDFPVIQAYVLIVAVLFIIFNTLADIINALLNPRLREGAR
>CP028468.1|AWQ23953.1|2493959_2495558_-|staphylopine-dependent-metal-ABC-transporter-substrate-binding-protein-CntA
MRKLTKMSAMLLASGLILTGCGGNKGLEEKKENKQLTYTTVKDIGDMNPHVYGGSMSAESMIYEPLVRNTKDGIKPLLSKKWDVSEDGKTYTFHLRDDVKFHDGTPFDADAVKKNIDAVQENKKLHSWLKISTLIDNVKVKDKYTVELNLKEAYQPALAELAMPRPYVFVSPKDFKNGTTKDGVKKFDGTGPFKLGEHKKDESADFNKNDQYWGEKSKLNKVQAKVMPAGETAFLSMKKGETNFAFTDDRGTDSLDKDSLKQLKDTGDYQVKRSQPMNTKMLVVNSGKKDNAVSDKTVRQAIGHMVNRDKIAKEILDGQEKPATQLFAKNVTDINFDMPTRKYDLKKAESLLDEAGWKKGKDSDVRQKDGKNLEMAMYYDKGSSSQKEQAEYLQAEFKKMGIKLNINGETSDKIAERRTSGDYDLMFNQTWGLLYDPQSTIAAFKAKNGYESATSGIENKDKIYNSIDDAFKIQNGKERSDAYKNILKQIDDEGIFIPISHGSMTVVAPKDLEKVSFTQSQYELPFNEMQYK
>CP028468.1|AWQ23954.1|2495700_2497002_-|staphylopine-biosynthesis-dehydrogenase
MSKLLMIGTGPVAIQLANICYLKSDYEIDMVGRASTSEKSKRLYQAYKKEKQFEVKIQNEAHQHLEGNFEINRLYKDVKNVKGEYETVVMACTADAYYDTLQQLSLETLQSVKHVILISPTFGSQMIVEQFMSKFNKDIEVISFSTYLGDTRIVDKEAPNHVLTTGVKKKLYMGSTHSNSTMCQRISALAEQLKIQLEVVESPLHAETRNSSLYVHPPLFMNDFSLKAIFEGTDVPVYVYKLFPEGPITMTLIREMRLMWKEMMAILQAFRVPSVNLIQFMVKENYPVRPETLDEGDIEHFEILPDILQEYLLYVRYTAILIDPFSQPDENGHYFDFSAVPFKQVYKNEQDVVQIPRMPSEDYYRTAMIQHIGKMLGIKTPMIDQFLTRYEASCQAYKDMHQDQQLSSQFNTNLFEGDKALVTNFLEINRTLS
>CP028468.1|AWQ23955.1|2496994_2497813_-|staphylopine-biosynthesis-enzyme-CntL
MNNFNNEIKLILQQYLEKFEAHYERVLQDDQYIEALETLMDDYSEFILNPIYEQQFNAWRDVEEKAQLIKSLQYITAQCVKQVEVIRARRLLDGQASTTGYFDNIEHCIDEEFGQCSIASNDKLLLVGSGAYPMTLIQVAKETGASVIGIDIDPQAVDLGRRIVNVLAPNEDITITDQKVSELKDIKDVTHIIFSSTIPLKYSILEELYDLTNENVVVAMRFGDGIKAIFNYPSQETAEDKWQCVNKHMRPQQIFDIALYKKAAIKVGITDV
>CP028468.1|AWQ23956.1|2497823_2498645_-|histidine-racemase-CntK
MNRQVIEFSKYNPSGNMTILVHSKHDASEYASIANQLMAATHVCCEQVGFIESTQNDDGNDFHLVMSGNEFCGNATMSYIHHLQESHLLKDQQFKVKVSGCSDLVQCAIHDCQYYEVQMPQAHRVVPTTINMGNHSWKAIEIIYETYVHYVIPVKQVTTEIQHLVESYVRKQQWNHKYKTVGMMLFDEQRQFLQPLIYIPEIQSLIWENSCGSGTASIGVFNNYQRNDACKDFTVHQPGGSILVTSKRCHQLGYQTSIKGQVTTVATGKAYIE
>CP028468.1|AWQ23957.1|2498731_2498926_+|hypothetical-protein
MTRIEKSLLQAHFRSVNYCHYNFVEHRTLIYVSGSYAVGAKQATVFLYNCNFLEGEPNSFPSIR

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Crispr_ID: CP028468_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028468_9

2616818-2616899

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP028468_9

>merge|CP028468|9|2616818-2616899|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGATGGGCCCCAACAAAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGG

>CP028468|9|9|2616818-2616899|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGG	ATGGGCCCCAACAAAGAGAAATTGGATTCCCAAT
TTCTACAGACAATGCAAGTTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
CP028468.1\|AWQ24297.1\|2614882_2615452_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
CP028468.1\|AWQ24064.1\|2618667_2619225_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
CP028468.1\|AWQ24059.1\|2615649_2616150_+\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ24062.1\|2617397_2618219_-\|NmrA/HSCARG-family-protein	unknown	unknown	gnl\|CDD\|187561
CP028468.1\|AWQ24066.1\|2620019_2621030_+\|amidohydrolase	unknown	unknown	gnl\|CDD\|225070
CP028468.1\|AWQ24063.1\|2618237_2618537_-\|DUF2316-domain-containing-protein	unknown	unknown	gnl\|CDD\|226806
CP028468.1\|AWQ24067.1\|2621049_2621880_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP028468.1\|AWQ24061.1\|2617003_2617381_-\|glyoxalase	unknown	unknown	gnl\|CDD\|226134
CP028468.1\|AWQ24068.1\|2622020_2623046_+\|NADP-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|176191
CP028468.1\|AWQ24054.1\|2607516_2608752_-\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
CP028468.1\|AWQ24058.1\|2614599_2614728_-\|hypothetical-protein	unknown	unknown	unknown
CP028468.1\|AWQ24056.1\|2612108_2612810_-\|transglycosylase	unknown	unknown	gnl\|CDD\|381607
CP028468.1\|AWQ24070.1\|2624256_2625597_-\|ferrous-iron-transporter-B	unknown	unknown	gnl\|CDD\|223447
CP028468.1\|AWQ24060.1\|2616369_2616600_+\|DUF896-domain-containing-protein	unknown	unknown	gnl\|CDD\|226677
CP028468.1\|AWQ24053.1\|2606737_2607505_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|181681
CP028468.1\|AWQ24052.1\|2605687_2606455_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
CP028468.1\|AWQ24069.1\|2623266_2624157_-\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
CP028468.1\|AWQ24057.1\|2613417_2614473_-\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
CP028468.1\|AWQ24065.1\|2619217_2619922_+\|KR-domain-containing-protein	unknown	unknown	gnl\|CDD\|187585
CP028468.1\|AWQ24055.1\|2609018_2610830_-\|O-acetyltransferase-OatA	unknown	unknown	gnl\|CDD\|224748

Protein	Function_ID	Function_description	E-value
CP028468.1\|AWQ24297.1\|2614882_2615452_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.43347e-07
CP028468.1\|AWQ24064.1\|2618667_2619225_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.49706e-13
CP028468.1\|AWQ24054.1\|2607516_2608752_-\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.13094e-34
CP028468.1\|AWQ24062.1\|2617397_2618219_-\|NmrA/HSCARG-family-protein	gnl\|CDD\|187561	cd05251, NmrA_like_SDR_a, NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs. NmrA and HSCARG like proteins. NmrA is a negative transcriptional regulator of various fungi, involved in the post-translational modulation of the GATA-type transcription factor AreA. NmrA lacks the canonical GXXGXXG NAD-binding motif and has altered residues at the catalytic triad, including a Met instead of the critical Tyr residue. NmrA may bind nucleotides but appears to lack any dehydrogenase activity. HSCARG has been identified as a putative NADP-sensing molecule, and redistributes and restructures in response to NADPH/NADP ratios. Like NmrA, it lacks most of the active site residues of the SDR family, but has an NAD(P)-binding motif similar to the extended SDR family, GXXGXXG. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Atypical SDRs are distinct from classical SDRs. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	4.51828e-85
CP028468.1\|AWQ24066.1\|2620019_2621030_+\|amidohydrolase	gnl\|CDD\|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	2.02807e-77
CP028468.1\|AWQ24063.1\|2618237_2618537_-\|DUF2316-domain-containing-protein	gnl\|CDD\|226806	COG4367, COG4367, Uncharacterized protein conserved in bacteria [Function unknown].	1.97434e-38
CP028468.1\|AWQ24067.1\|2621049_2621880_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.86854e-18
CP028468.1\|AWQ24061.1\|2617003_2617381_-\|glyoxalase	gnl\|CDD\|226134	COG3607, COG3607, Predicted lactoylglutathione lyase [General function prediction only].	1.48638e-58
CP028468.1\|AWQ24068.1\|2622020_2623046_+\|NADP-dependent-oxidoreductase	gnl\|CDD\|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.78714e-97
CP028468.1\|AWQ24056.1\|2612108_2612810_-\|transglycosylase	gnl\|CDD\|381607	cd13925, RPF, core lysozyme-like domain of resuscitation-promoting factor proteins. Resuscitation-promoting factor (RPF) proteins, found in various (G+C)-rich Gram-positive bacteria, act to reactivate cultures from stationary phase. This protein shares elements of the structural core of lysozyme and related proteins. Furthermore, it shares a conserved active site glutamate which is required for activity, and has a polysaccharide binding cleft that corresponds to the peptidoglycan binding cleft of lysozyme. Muralytic activity of Rpf in Micrococcus luteus correlates with resuscitation, supporting a mechanism dependent on cleavage of peptidoglycan by RPF.	2.63325e-06
CP028468.1\|AWQ24070.1\|2624256_2625597_-\|ferrous-iron-transporter-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	5.10424e-93
CP028468.1\|AWQ24060.1\|2616369_2616600_+\|DUF896-domain-containing-protein	gnl\|CDD\|226677	COG4224, COG4224, Uncharacterized protein conserved in bacteria [Function unknown].	6.01061e-31
CP028468.1\|AWQ24053.1\|2606737_2607505_-\|AAA-family-ATPase	gnl\|CDD\|181681	PRK09183, PRK09183, transposase/IS protein; Provisional.	2.85352e-66
CP028468.1\|AWQ24052.1\|2605687_2606455_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	9.90876e-31
CP028468.1\|AWQ24069.1\|2623266_2624157_-\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	1.21918e-76
CP028468.1\|AWQ24057.1\|2613417_2614473_-\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	5.38046e-117
CP028468.1\|AWQ24065.1\|2619217_2619922_+\|KR-domain-containing-protein	gnl\|CDD\|187585	cd05324, carb_red_PTCR-like_SDR_c, Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs. PTCR is a classical SDR which catalyzes the NADPH-dependent reduction of ketones on steroids and prostaglandins. Unlike most SDRs, PTCR functions as a monomer. This subgroup also includes human carbonyl reductase 1 (CBR1) and CBR3. CBR1 is an NADPH-dependent SDR with broad substrate specificity and may be responsible for the in vivo reduction of quinones, prostaglandins, and other carbonyl-containing compounds. In addition it includes poppy NADPH-dependent salutaridine reductase which catalyzes the stereospecific reduction of salutaridine to 7(S)-salutaridinol in the biosynthesis of morphine, and Arabidopsis SDR1,a menthone reductase, which catalyzes the reduction of menthone to neomenthol, a compound with antimicrobial activity; SDR1 can also carry out neomenthol oxidation. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	3.1238e-67
CP028468.1\|AWQ24055.1\|2609018_2610830_-\|O-acetyltransferase-OatA	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	3.4224e-84

>CP028468.1|AWQ24060.1|2616369_2616600_+|DUF896-domain-containing-protein
MKILDRINELANKEKVQPLTVAEKQEQHALRQDYLSMIRGQVLTTFSTIKVVDPIGQDVTPDKVYDLRQQYGYIQN
>CP028468.1|AWQ24059.1|2615649_2616150_+|hypothetical-protein
MTSIFVFAYLNNTSDNMLFRQQMIYACLLANVRHSSIVCLNNTCRIVDIRCLNTKIGGIDVSETDESQGFERTHNILNINQSSLGVVTYITNKLKSTLKQHIIIACGKKRIDYRLSYNFYTTYYDNVEIKKIDCEYTYAMPIAILIRHMMSFDNDYFFAQLRHPVL
>CP028468.1|AWQ24297.1|2614882_2615452_+|TetR/AcrR-family-transcriptional-regulator
MMESKSIDPRIVRTKQLLVDAFLKISREKKLSQITVKDITDIATLNRATFYAHFTDKEDLLDYTLSVTILKDLNDNLSISNVINEKVLRNIFISIASYIKDAAKSCELNSEAFCNKAHQRINNELEDIFAIMLENSYPEHQRDIIVNSASFLAAGISGLALHWFNTSQETADVFIDRNLPFLIHHIAHF
>CP028468.1|AWQ24058.1|2614599_2614728_-|hypothetical-protein
MDFKNEDKIKVYCNNMFEKLPISLSKNSEFCDILFFIVLSYR
>CP028468.1|AWQ24057.1|2613417_2614473_-|PTS-transporter-subunit-IIC
MTSIKTITPKDFIFRVLSGVAIGIVAGLVPNAILGEIFKYFMDYHPIFKTLLGVVVAIQFTVPALIGALVAMKFDLSPLAIAVVASAAYVGSGAAQFKNGAWMITGIGDLINTMITAAIAVLFILLIQHRVGSMALIVFPTVVGGISGAIGVLILPYTKMITTAIGNMVNGFTELQPIVMSILISMVFSLIIISPLSTVAIAFAIGITGLAAGSASIGISATEAVLIIGTSKVNRLGVPLSVFFGGVKMMIPNMVKYPILMLPILTTAIVSGLVSALVGIHGTKESAGFGFIGMVGPINAFKFMEVDSAWLSVLLIVVAFFVVPFVTAWLADIIYRKVFRLYTNDIFKFMG
>CP028468.1|AWQ24056.1|2612108_2612810_-|transglycosylase
MKKTIMASSLAVALGVTGYAASTGHEAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADYTTSYNQGSNVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSSAAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF
>CP028468.1|AWQ24055.1|2609018_2610830_-|O-acetyltransferase-OatA
MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSGGFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFTLIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLLFPLVITFLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLLGCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYIISFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIPVYVYVIEIVLTALMAEISYRFIETPIRKKGFKAFAFLPKKKGQFARTVLVILLLVPSIVVLSGQFDALGKQHEAEKKEKKTEFKTTKKKVVKKDKQEDKQTANSKEDIKKSSPLLIGDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNGAFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASAGHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK
>CP028468.1|AWQ24054.1|2607516_2608752_-|IS21-family-transposase
MRHDIYEGVLFYIMKGIKPNYAELGRQYNCDPRTVKKYYEAGKENELERLKKRQQNKKASKLDPFKEIINKKIELGCTAMAIFKYIEKKGYEGKYTILREYCKNKKQNETKKATIRVETNPGIAAQVDWKEDMVMHDKFGRTYQFNIFLYVLHYSKMKYITLTWDRKQDTLFECLKDAFEYTEGVPKEIWFDNMRTVVDRPRTQYKKVVFNNLFYQFSKDANFEPIACRPYRPQTKGSVESLAKFVEQRLRPYDYEFYDAVELIGLVNDLCHELNHLEISQATEQRPIDVFNYEEKEHLNSFNAKLLDTYIENECIRIVSKESMINFRKGKYSVPTKYIGEEVQVIFNNSTDELLIYYDGELIRRHNLSERKFNYIVEDMSEILKSDVFKHKDDKEILTYIENSLLLYDEI
>CP028468.1|AWQ24053.1|2606737_2607505_-|AAA-family-ATPase
MNTNHQKLLNNFEILKLKKFKDYYPNYIELLSKNEKSLTEILIDLTEKEIEYQSELKFKRAVNSARFPKIKYLHDFDFMFQPSINQQEILTLKSMHFLEDSINICFLGNSGVGKTHLAISLGIEACKQNIKTRFYTFKELIDLLTVSDSKGIINKTLKQLSRIELLIIDEIGYTPITKEQADLFYQLMSLRYEWKSTIITTNIPFSSWGESFSNKIVSAAIIDRLVHHSKVFKITGESYRLKDYKTEKSLNIRQS
>CP028468.1|AWQ24052.1|2605687_2606455_-|CHAP-domain-containing-protein
MKKIVTATIATAGLATIAFAGHDAQAAEQNNNGYNSNDAQSYSYTYTIDAQGNYHYTWTGNWNPSQLTQNNTYYYNNYNTYSYNNASYNNYYNHSYQYNNYTNNSQTATNNYYTGGSGASYSTTSNNVHVTTTAAPSSNGRSISNGYASGSNLYTSGQCTYYVFDRVGGKIGSTWGNASNWASAAASSGYTVNNTPKAGAIMQTTQGYYGHVAYVEGVNSNGSVRVSEMNYGHGAGVVTSRTISANQAGSYNFIH
>CP028468.1|AWQ24061.1|2617003_2617381_-|glyoxalase
MIQSMWFNLHVQDLEKSAQFYKALGFKINRNPQMLDKMVGIQIGQTTVILIENKHFQNVSQQSLNTEPNEVMISLGVNTNEEVDQLVNKVKEAGGTVVQEPTVSQGFYGAMFKDLDGHHFNFLVC
>CP028468.1|AWQ24062.1|2617397_2618219_-|NmrA/HSCARG-family-protein
MKDILVIGATGKQGNAVVKQLLEDGWYVSALTRNKNNRKLSDIGHPHLSIVEGDLSDSDSLQSAMKGKYGLYSIQPIVKDDVSEELRQGMKIIEIAEQENIQHIVYSTAGGVNRNRTGPHFEVLAKIENRLMESNINATVIKPSFFMDNFLRIAKVEDERITLPEFINPNIKFTMISSIDIAKIASYIFAHPQSFTHQSIEIGSDEVTLSEAATIFSEVTGKSTVIEGEFVSSVAEKQWLEEKGYEVDFELMAEINPTRLSLSDWLKVQDYNK
>CP028468.1|AWQ24063.1|2618237_2618537_-|DUF2316-domain-containing-protein
MSLNKEQRRITAEELQAHFEASTLSVQMIAEKLNVTTEDVEKALAMKAPLGIFSHQLQRFIHLVWDVRNVINDNIKENGQTPEPYTYLKGEKEDYWFLR
>CP028468.1|AWQ24064.1|2618667_2619225_+|TetR/AcrR-family-transcriptional-regulator
MRKDAKENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTLYRHFKDKSDLCYYVIQRDLDIFITHFKQIKDDYHSDYEVMQVSLDYLLQFKIDNKALLQCIEAGNNKLRFYQSAFYQELFNFYYDLFKSDDDIYKKFKTDMLLQALSTSVFAFQIEHRHISIEAYRNYLLNIYLDEVERND
>CP028468.1|AWQ24065.1|2619217_2619922_+|KR-domain-containing-protein
MTKIVLITGGNKGLGYASAEALKALGYKVYIGSRNDVRGQQASQKLGVHYVQLDVTSDYSVKNAYNMIAEKEGRLDILINNAGISGQFSAPSKLTPRDVEEVYQTNVFGIVRMMNTFVPLLEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSSKSAVTMLTLQYAKGLPNMQINAADPGATNTDLVGDFSNNSKHVSEGIKPIIQLATIDADGPTGTFINGDGEMPW
>CP028468.1|AWQ24066.1|2620019_2621030_+|amidohydrolase
MKSITFEEHYVIEDIQKETMNAISADPKGVPMKVMLEGLEKKTGFTNADELSHHDERIQFMNNQDVQIQVLSYGNGSPSNLVGQKAIELCQKANDQLANYIAQYPNRFVGFATLPINEPEAAAREFERCINDLGFKGALIMGRAQDGFLDQDKYDIIFKTAENLDVPIYLHPAPVNSDIYQSYYKGNYPEVTAATFACFGYGWHIDVGIHAIHLVLSGIFDRYPKLNMIIGHWGEFIPFFLERMDEALFAEHLNHPVSYYFKNNFYITPSGMLTKPQFDLVKKEVGIDRILYAADYPYIEPEKLGVFLDELGLTDEEKEKISYTNGAKLLGLSSNN
>CP028468.1|AWQ24067.1|2621049_2621880_+|alpha/beta-hydrolase
METLELQGAKLRYHQVGQGPVLIFIPGANGTGDIFLPLAEQLKDHFTVVAVDRRDYGESELTEPLPDSASNPDSDYRVKRDAQDIAELAKSLSDEPVYILGSSSGSIVAMHVLKDYPEVVKKIAFHEPPINTFLPDSTYWKDKNDDIVHQILTEGLEKGMKTFGETLNIAPIDAKMMSQPADTEEGRIEQYKRTMFWSEFEIRQYTHSDITLDDFTKYNDKITLLNGTDSRGSFPQDVNFYINNETGIPIVDIPGGHLGYIQKPEGFADVLLNMWS
>CP028468.1|AWQ24068.1|2622020_2623046_+|NADP-dependent-oxidoreductase
MKAIQIKKYNKNRDVQIRDITIPEIKSTEVLVKVAYAAINPLENLTINGSVKLIQNYKMPQTIGNELTGTIVKVGSKVEDYKLGDKIYSRLPIDRIGAFAEYVSIESNAIAKLPKNLNLKTGAAVPLTGLTAYQAITEELKAIPGKTLFIPGGSGSFGQMAVPIAKSLGLKVIVSGSPRLKDQFLAKGVDQYIDYKTENYCEVLSDIDYVIDTLGPNEFDKELSVMKPGGTIVSLINAPNKAFAVKNNFSPFKKLLFGLAGKKFDKKAQKKSIDYRFIFVRSDGEQLKILNKIIEQNNIIPDIDDHIFTIDEIDKALDYTFNHHTNGKVLIRIDNSDNTIY
>CP028468.1|AWQ24069.1|2623266_2624157_-|GTP-binding-protein
MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSVDGALVSEDIPLSELTEGCICCAMKADVSEQLHQLYLKEQPDIVFIECSGIAEPVSVLDACLTPILAPFTTITHMIGVVDASMYKHIKSFPKDIQGLFYEQLAYCSVLFVNKIDSADVETTSKLLKDLEVINPEADIQVGMHGSVTLPISVRQMTVTSDNKHESLHKTINHQFVQSPVKCTKAEFIKRLACLPSHIYRLKGFMTFEDTAHTYLIQFTQGQYELTPVAFSKKVPEYLVLIGKGISKEDYQCLEQ
>CP028468.1|AWQ24070.1|2624256_2625597_-|ferrous-iron-transporter-B
MLEVKYDMRTGHYTPIPNEPHYLVISHADKLNATEKAKLRLLIIKQKLDISLAESVVSSPIASEHVIEQLTLFQHERRHLRPKISATFLAWLLIFLMFALPIGIAYQFSDWFQNQYVSAWIEYLTQTTLLNHDILQHILFGDYGVLSLGTYSLVWALPVVILISLSTAIIDQTGFKSWMIWAIEPSMLRIGLQGNDIVPLLEGFGCNAAAISQAAHQCHTCTKTQCMSLISFGSSCSYQIGATLSIFSVAGKSWLFMPYLILVLLGGILHNRIWLKKNNQQLSVPLPYDRQLHMPNIRQMLLQMWQNIQMFIVQALPIFITICLIVSILSLTPILNVLSQIFTPILSLLGISSELSPGILFSMIRKDGMLLFNLHQGALLQGMTATQLLLLVFFSSTFTACSVTMTMLLKHLGGQSALKLIGKQMLTSLSLVIGVGIIVKIVMLII

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	377621-377648	0	1.0
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	606342-606369	0	1.0
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	778202-778229	0	1.0
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	1015945-1015972	0	1.0
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	1305875-1305902	0	1.0
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	1380085-1380112	0	1.0
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	1792663-1792690	0	1.0
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	1899162-1899189	0	1.0
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	2258855-2258882	0	1.0
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	2616802-2616829	0	1.0
CP028468_1	1.2\|261440\|29\|CP028468\|CRISPRCasFinder	261440-261468	29	CP028468.1	261329-261357	0	1.0
CP028468_1	1.2\|261440\|29\|CP028468\|CRISPRCasFinder	261440-261468	29	CP028468.1	787181-787209	0	1.0
CP028468_1	1.2\|261440\|29\|CP028468\|CRISPRCasFinder	261440-261468	29	CP028468.1	990033-990061	0	1.0
CP028468_1	1.2\|261440\|29\|CP028468\|CRISPRCasFinder	261440-261468	29	CP028468.1	2453302-2453330	0	1.0
CP028468_4	4.1\|1897722\|26\|CP028468\|CRISPRCasFinder	1897722-1897747	26	CP028468.1	778222-778247	0	1.0
CP028468_4	4.1\|1897722\|26\|CP028468\|CRISPRCasFinder	1897722-1897747	26	CP028468.1	1899182-1899207	0	1.0
CP028468_4	4.1\|1897722\|26\|CP028468\|CRISPRCasFinder	1897722-1897747	26	CP028468.1	2258875-2258900	0	1.0
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	337529-337556	1	0.964
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	890293-890320	1	0.964
CP028468_1	1.2\|261440\|29\|CP028468\|CRISPRCasFinder	261440-261468	29	CP028468.1	2107675-2107703	1	0.966
CP028468_2	2.1\|606380\|28\|CP028468\|CRISPRCasFinder	606380-606407	28	CP028468.1	1897781-1897808	1	0.964
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	1092333-1092360	2	0.929
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	1697657-1697684	2	0.929
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	1908512-1908539	2	0.929
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	1908628-1908655	2	0.929
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	2269663-2269690	2	0.929
CP028468_1	1.1\|261385\|28\|CP028468\|CRISPRCasFinder	261385-261412	28	CP028468.1	2733576-2733603	2	0.929
CP028468_1	1.2\|261440\|29\|CP028468\|CRISPRCasFinder	261440-261468	29	CP028468.1	337473-337501	2	0.931
CP028468_1	1.2\|261440\|29\|CP028468\|CRISPRCasFinder	261440-261468	29	CP028468.1	606454-606482	2	0.931
CP028468_1	1.2\|261440\|29\|CP028468\|CRISPRCasFinder	261440-261468	29	CP028468.1	1016002-1016030	2	0.931
CP028468_1	1.2\|261440\|29\|CP028468\|CRISPRCasFinder	261440-261468	29	CP028468.1	1092275-1092303	2	0.931
CP028468_1	1.2\|261440\|29\|CP028468\|CRISPRCasFinder	261440-261468	29	CP028468.1	1305933-1305961	2	0.931
CP028468_1	1.2\|261440\|29\|CP028468\|CRISPRCasFinder	261440-261468	29	CP028468.1	1380142-1380170	2	0.931
CP028468_1	1.2\|261440\|29\|CP028468\|CRISPRCasFinder	261440-261468	29	CP028468.1	1578220-1578248	2	0.931
CP028468_1	1.2\|261440\|29\|CP028468\|CRISPRCasFinder	261440-261468	29	CP028468.1	1592695-1592723	2	0.931
CP028468_1	1.2\|261440\|29\|CP028468\|CRISPRCasFinder	261440-261468	29	CP028468.1	1897819-1897847	2	0.931
CP028468_9	9.1\|2616842\|34\|CP028468\|CRISPRCasFinder	2616842-2616875	34	CP028468.1	989987-990020	2	0.941

1. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 377621-377648, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

2. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 606342-606369, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

3. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 778202-778229, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

4. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 1015945-1015972, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

5. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 1305875-1305902, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

6. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 1380085-1380112, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

7. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 1792663-1792690, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

8. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 1899162-1899189, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

9. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 2258855-2258882, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

10. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 2616802-2616829, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

11. spacer 1.2|261440|29|CP028468|CRISPRCasFinder matches to position: 261329-261357, mismatch: 0, identity: 1.0

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcggaaagtcagcttacaataatg	Protospacer
*****************************

12. spacer 1.2|261440|29|CP028468|CRISPRCasFinder matches to position: 787181-787209, mismatch: 0, identity: 1.0

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcggaaagtcagcttacaataatg	Protospacer
*****************************

13. spacer 1.2|261440|29|CP028468|CRISPRCasFinder matches to position: 990033-990061, mismatch: 0, identity: 1.0

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcggaaagtcagcttacaataatg	Protospacer
*****************************

14. spacer 1.2|261440|29|CP028468|CRISPRCasFinder matches to position: 2453302-2453330, mismatch: 0, identity: 1.0

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcggaaagtcagcttacaataatg	Protospacer
*****************************

15. spacer 4.1|1897722|26|CP028468|CRISPRCasFinder matches to position: 778222-778247, mismatch: 0, identity: 1.0

cgaaattctctgtgttggggcccaca	CRISPR spacer
cgaaattctctgtgttggggcccaca	Protospacer
**************************

16. spacer 4.1|1897722|26|CP028468|CRISPRCasFinder matches to position: 1899182-1899207, mismatch: 0, identity: 1.0

cgaaattctctgtgttggggcccaca	CRISPR spacer
cgaaattctctgtgttggggcccaca	Protospacer
**************************

17. spacer 4.1|1897722|26|CP028468|CRISPRCasFinder matches to position: 2258875-2258900, mismatch: 0, identity: 1.0

cgaaattctctgtgttggggcccaca	CRISPR spacer
cgaaattctctgtgttggggcccaca	Protospacer
**************************

18. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 337529-337556, mismatch: 1, identity: 0.964

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaagcaa	Protospacer
***********************.****

19. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 890293-890320, mismatch: 1, identity: 0.964

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaagcaa	Protospacer
***********************.****

20. spacer 1.2|261440|29|CP028468|CRISPRCasFinder matches to position: 2107675-2107703, mismatch: 1, identity: 0.966

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcggaaagtcagcttacattaatg	Protospacer
*********************** *****

21. spacer 2.1|606380|28|CP028468|CRISPRCasFinder matches to position: 1897781-1897808, mismatch: 1, identity: 0.964

ggtgtgggccccaacacagagaatttca	CRISPR spacer
ggtgtgggccccaacatagagaatttca	Protospacer
****************.***********

22. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 1092333-1092360, mismatch: 2, identity: 0.929

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcaaaaagaaattctacagacaa	Protospacer
*******.****************.***

23. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 1697657-1697684, mismatch: 2, identity: 0.929

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaaacaa	Protospacer
***********************..***

24. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 1908512-1908539, mismatch: 2, identity: 0.929

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaggaaattctacagacaa	Protospacer
***********.************.***

25. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 1908628-1908655, mismatch: 2, identity: 0.929

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaggaaattctacagacaa	Protospacer
***********.************.***

26. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 2269663-2269690, mismatch: 2, identity: 0.929

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcaaaaagaaattctacagacaa	Protospacer
*******.****************.***

27. spacer 1.1|261385|28|CP028468|CRISPRCasFinder matches to position: 2733576-2733603, mismatch: 2, identity: 0.929

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaaacaa	Protospacer
***********************..***

28. spacer 1.2|261440|29|CP028468|CRISPRCasFinder matches to position: 337473-337501, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

29. spacer 1.2|261440|29|CP028468|CRISPRCasFinder matches to position: 606454-606482, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcgaaaagacagcttacaataatg	Protospacer
********.**** ***************

30. spacer 1.2|261440|29|CP028468|CRISPRCasFinder matches to position: 1016002-1016030, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

31. spacer 1.2|261440|29|CP028468|CRISPRCasFinder matches to position: 1092275-1092303, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

32. spacer 1.2|261440|29|CP028468|CRISPRCasFinder matches to position: 1305933-1305961, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

33. spacer 1.2|261440|29|CP028468|CRISPRCasFinder matches to position: 1380142-1380170, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

34. spacer 1.2|261440|29|CP028468|CRISPRCasFinder matches to position: 1578220-1578248, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

35. spacer 1.2|261440|29|CP028468|CRISPRCasFinder matches to position: 1592695-1592723, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcgaaaagacagcttacaataatg	Protospacer
********.**** ***************

36. spacer 1.2|261440|29|CP028468|CRISPRCasFinder matches to position: 1897819-1897847, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

37. spacer 9.1|2616842|34|CP028468|CRISPRCasFinder matches to position: 989987-990020, mismatch: 2, identity: 0.941

atgggccccaacaaagagaaattggattcccaat	CRISPR spacer
atgggccccaacaaagaggaattggatttccaat	Protospacer
******************.*********.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

710789 : 718610

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ22249.1\|710789_711845_-	two-component sensor histidine kinase	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
AWQ22250.1\|711844_712531_-	DNA-binding response regulator	NA	NA	NA	NA
AWQ22251.1\|712505_712979_-	DoxX family membrane protein	NA	NA	NA	NA
AWQ22252.1\|713321_713762_-	hypothetical protein	NA	NA	NA	NA
AWQ22253.1\|714041_714626_-	hypothetical protein	NA	NA	NA	NA
AWQ22254.1\|714724_715438_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	9.3e-51	42.7
AWQ22255.1\|715441_715861_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
AWQ22256.1\|715862_716531_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
AWQ22257.1\|716881_717475_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	3.7e-37	42.4
AWQ22258.1\|717458_718610_+	aminodeoxychorismate synthase component I	S4VNU7	Pandoravirus	3.5e-23	35.7

DBSCAN-SWA_2

730583 : 744551

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ22268.1\|730583_731639_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	1.8e-21	26.4
AWQ22269.1\|731799_732342_+	5'(3')-deoxyribonucleotidase	NA	NA	NA	NA
AWQ22270.1\|732734_733652_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	6.2e-07	22.4
AWQ22271.1\|733742_733844_+	hypothetical protein	NA	NA	NA	NA
AWQ22272.1\|733921_735427_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
AWQ22273.1\|735764_736265_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
AWQ22274.1\|736284_737151_-	EamA/RhaT family transporter	NA	NA	NA	NA
AWQ22275.1\|737535_737802_+	ribonucleoside-diphosphate reductase	NA	NA	NA	NA
AWQ22276.1\|737951_738350_+	protein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
AWQ22277.1\|738312_740418_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.6
AWQ22278.1\|740537_741509_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
AWQ22279.1\|741878_742850_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	7.8e-141	80.2
AWQ22280.1\|742836_743793_+	iron ABC transporter permease	A0A2H4J116	uncultured_Caudovirales_phage	6.1e-05	57.8
AWQ22281.1\|743789_744551_+	iron ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	4.2e-17	30.6

DBSCAN-SWA_3

916768 : 971648

Lactococcus_phage(33.33%)

holin,tRNA,transposase,bacteriocin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ22444.1\|916768_917758_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
AWQ22445.1\|918052_918448_+	transcriptional regulator Spx	NA	NA	NA	NA
AWQ22446.1\|918659_919145_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	4.9e-19	35.4
AWQ22447.1\|919560_920280_+	adaptor protein MecA	NA	NA	NA	NA
AWQ22448.1\|920400_921387_+	competence protein CoiA	NA	NA	NA	NA
AWQ22449.1\|921434_923243_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	5.5e-47	24.5
AWQ22450.1\|923702_924509_-	DsbA family protein	NA	NA	NA	NA
AWQ22451.1\|924531_924897_-	globin	NA	NA	NA	NA
AWQ22452.1\|925000_925594_-	CYTH domain-containing protein	NA	NA	NA	NA
AWQ22453.1\|925779_926127_+	hypothetical protein	NA	NA	NA	NA
AWQ22454.1\|926143_926779_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
AWQ22455.1\|926795_927605_+	NAD(+) kinase	NA	NA	NA	NA
AWQ22456.1\|927601_928456_+	RluA family pseudouridine synthase	NA	NA	NA	NA
AWQ22457.1\|928476_929862_+	magnesium transporter	NA	NA	NA	NA
AWQ22458.1\|929871_931716_+	sodium:proton antiporter	NA	NA	NA	NA
AWQ22459.1\|931993_932764_+	enoyl-[acyl-carrier-protein] reductase FabI	NA	NA	NA	NA
AWQ22460.1\|932960_934046_-	AI-2E family transporter	NA	NA	NA	NA
AWQ22461.1\|934387_935956_+	alanine:cation symporter family protein	NA	NA	NA	NA
AWQ22462.1\|936100_936859_+	esterase family protein	NA	NA	NA	NA
AWQ22463.1\|937052_937562_+	hypothetical protein	NA	NA	NA	NA
AWQ22464.1\|937674_938883_-	MFS transporter	NA	NA	NA	NA
AWQ22465.1\|938842_940018_-	diacylglycerol beta-glucosyltransferase	NA	NA	NA	NA
AWQ22466.1\|940450_941935_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
AWQ22467.1\|941915_942176_+	hypothetical protein	NA	NA	NA	NA
AWQ22468.1\|942175_943738_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	1.7e-36	28.2
AWQ22469.1\|944039_944843_+	hypothetical protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
AWQ22470.1\|945061_947386_+	PDZ domain-containing protein	W5SAB9	Pithovirus	2.8e-11	27.4
AWQ22471.1\|947402_948761_+	Ktr system potassium uptake protein D	NA	NA	NA	NA
AWQ22472.1\|948899_950411_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
AWQ22473.1\|950899_951469_-	competence protein ComK	NA	NA	NA	NA
AWQ22474.1\|951678_951897_+	IDEAL domain-containing protein	NA	NA	NA	NA
AWQ22475.1\|951977_952964_-	lipoate--protein ligase	NA	NA	NA	NA
AWQ22476.1\|953162_953339_+	DUF2187 domain-containing protein	NA	NA	NA	NA
AWQ24239.1\|954175_954253_+\|holin	putative holin-like toxin	NA	NA	NA	NA
AWQ24240.1\|954899_955172_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
AWQ22477.1\|955215_956172_+	hypothetical protein	NA	NA	NA	NA
AWQ22478.1\|956269_957505_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	3.3e-104	49.1
AWQ22479.1\|957516_958284_+	AAA family ATPase	A0A059NT77	Lactococcus_phage	6.3e-53	44.6
AWQ22480.1\|959385_959706_+	YxeA family protein	NA	NA	NA	NA
AWQ22481.1\|959702_960344_+\|bacteriocin	bacteriocin ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-19	33.7
AWQ22482.1\|960431_960722_-	hypothetical protein	NA	NA	NA	NA
AWQ22483.1\|960862_961000_+	poly(glycerol-phosphate) alpha-glucosyltransferase	NA	NA	NA	NA
AWQ22484.1\|961088_961445_-	DoxX family protein	NA	NA	NA	NA
AWQ22485.1\|962938_963070_-	hypothetical protein	NA	NA	NA	NA
AWQ22486.1\|963133_963424_-	NINE protein	A0A060AN66	Enterococcus_phage	5.7e-07	38.0
AWQ22487.1\|963513_964065_+	N-acetyltransferase	NA	NA	NA	NA
AWQ22488.1\|964116_965055_-	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
AWQ24242.1\|965205_965283_+	hypothetical protein	NA	NA	NA	NA
AWQ24241.1\|965386_966598_+	isochorismate synthase	NA	NA	NA	NA
AWQ22489.1\|966584_968258_+	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
AWQ22490.1\|968244_969048_+	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
AWQ22491.1\|969040_969862_+	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
AWQ22492.1\|970099_970429_-	staphostatin B	NA	NA	NA	NA
AWQ22493.1\|970466_971648_-\|protease	cysteine protease staphopain B	NA	NA	NA	NA

DBSCAN-SWA_4

991341 : 999814

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ22511.1\|991341_991824_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	4.0e-21	44.0
AWQ22512.1\|991810_992935_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
AWQ22513.1\|992938_993643_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	3.6e-47	41.6
AWQ22514.1\|993642_993906_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AWQ22515.1\|993907_994579_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
AWQ22516.1\|994571_996761_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	4.6e-141	39.8
AWQ22517.1\|996739_998224_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.2e-45	31.7
AWQ22518.1\|998216_999245_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
AWQ22519.1\|999247_999814_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.5e-30	40.7

DBSCAN-SWA_5

1259759 : 1266117

Staphylococcus_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ22760.1\|1259759_1259957_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	1.7e-10	48.4
AWQ22761.1\|1260645_1260870_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	4.3e-18	71.0
AWQ22762.1\|1261163_1261370_+	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	1.3e-13	59.7
AWQ22763.1\|1262070_1262181_+	hypothetical protein	NA	NA	NA	NA
AWQ22764.1\|1262608_1262794_+	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.4e-19	78.7
AWQ22765.1\|1263305_1263410_+	hypothetical protein	NA	NA	NA	NA
AWQ22766.1\|1263364_1263538_+	hypothetical protein	NA	NA	NA	NA
AWQ22767.1\|1263538_1263790_+	hypothetical protein	NA	NA	NA	NA
AWQ22768.1\|1264102_1264870_-	AAA family ATPase	A0A059NT77	Lactococcus_phage	6.3e-53	44.6
AWQ22769.1\|1264881_1266117_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	3.3e-104	49.1

DBSCAN-SWA_6

1549819 : 1558149

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ23030.1\|1549819_1550605_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
AWQ23031.1\|1550730_1551621_-	endonuclease	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
AWQ23032.1\|1551630_1552977_-	DEAD/DEAH box family ATP-dependent RNA helicase	A0A1V0SIR5	Klosneuvirus	9.1e-55	33.7
AWQ23033.1\|1553090_1554191_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
AWQ23034.1\|1554193_1554871_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
AWQ23035.1\|1555001_1556108_-	RNA polymerase sigma factor SigA	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
AWQ23036.1\|1556331_1558149_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	7.9e-54	36.3

DBSCAN-SWA_7

1627483 : 1636526

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ23103.1\|1627483_1628002_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
AWQ23104.1\|1628023_1630297_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.1e-63	29.0
AWQ23105.1\|1630499_1632779_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
AWQ23106.1\|1633053_1633314_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
AWQ23107.1\|1633332_1634472_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
AWQ23108.1\|1634494_1635520_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
AWQ23109.1\|1635521_1636526_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_8

1775383 : 1784387

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ23231.1\|1775383_1776385_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	4.5e-184	99.4
AWQ23232.1\|1776506_1776971_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
AWQ23233.1\|1776983_1778165_-	riboflavin biosynthesis protein RibBA	A0A2H4PQS2	Staphylococcus_phage	1.7e-227	100.0
AWQ23234.1\|1778175_1778808_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
AWQ24266.1\|1778814_1779846_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.0e-196	98.8
AWQ23235.1\|1780338_1781841_-	pyridine nucleotide-disulfide oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
AWQ23236.1\|1782367_1782682_+	ArsR family transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	1.3e-52	98.1
AWQ23237.1\|1782681_1783974_+	arsenical efflux pump membrane protein ArsB	A0A2H4PQU3	Staphylococcus_phage	7.5e-216	94.2
AWQ23238.1\|1783991_1784387_+	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	4.5e-71	96.9

DBSCAN-SWA_9

1794306 : 1813555

Staphylococcus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ23250.1\|1794306_1794672_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	4.8e-59	99.2
AWQ23251.1\|1794668_1795022_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.9e-20	82.9
AWQ23252.1\|1797117_1797951_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	6.0e-158	99.3
AWQ23253.1\|1798167_1799076_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	2.9e-137	98.7
AWQ23254.1\|1799200_1800394_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	2.2e-217	99.5
AWQ23255.1\|1800764_1802357_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
AWQ24267.1\|1802734_1803481_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	7.8e-141	97.6
AWQ23256.1\|1803485_1803959_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	3.6e-83	98.1
AWQ23257.1\|1804024_1804282_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	2.0e-40	90.6
AWQ23258.1\|1804278_1805280_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.8e-186	97.9
AWQ23259.1\|1805284_1806763_-	2-succinylbenzoate-CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.6e-283	97.6
AWQ24268.1\|1806921_1807377_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.6e-80	99.3
AWQ23260.1\|1807678_1808329_+	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	4.8e-54	92.6
AWQ23261.1\|1808409_1809405_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	1.9e-70	95.2
AWQ23262.1\|1809480_1810107_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	6.4e-88	91.8
AWQ23263.1\|1810147_1810489_+	DUF3969 domain-containing protein	A0A2H4PQN6	Staphylococcus_phage	2.5e-54	92.9
AWQ23264.1\|1810589_1811162_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	7.8e-24	93.1
AWQ23265.1\|1811358_1811928_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	1.2e-77	95.0
AWQ23266.1\|1812113_1812299_-	hypothetical protein	NA	NA	NA	NA
AWQ23267.1\|1812300_1812477_-	hypothetical protein	NA	NA	NA	NA
AWQ23268.1\|1812487_1812871_-	hypothetical protein	NA	NA	NA	NA
AWQ23269.1\|1813052_1813277_-\|transposase	transposase	A0A2H4PQV6	Staphylococcus_phage	6.8e-24	86.8
AWQ23270.1\|1813450_1813555_-	hypothetical protein	A0A2H4PQU1	Staphylococcus_phage	7.2e-05	87.5

DBSCAN-SWA_10

1820525 : 1828188

Staphylococcus_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ23279.1\|1820525_1821654_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	5.2e-80	54.7
AWQ23280.1\|1822480_1822666_+	hypothetical protein	NA	NA	NA	NA
AWQ23281.1\|1822883_1823660_-	enterotoxin	NA	NA	NA	NA
AWQ23282.1\|1823942_1824698_-	exotoxin	A0A075M4C7	Staphylococcus_phage	6.0e-40	41.4
AWQ23283.1\|1824736_1825507_-	exotoxin	A0A097PAT7	Streptococcus_pyogenes_phage	6.3e-45	43.6
AWQ23284.1\|1825660_1826389_-	exotoxin	A0A1X9H080	Staphylococcus_phage	1.1e-27	39.2
AWQ23285.1\|1826423_1827143_-	exotoxin	A0A1X9H080	Staphylococcus_phage	2.3e-25	35.8
AWQ23286.1\|1827423_1828188_-	exotoxin	A0A1X9H080	Staphylococcus_phage	2.3e-31	37.1

DBSCAN-SWA_11

1912228 : 2024575

137

Staphylococcus_phage(82.47%)

coat,holin,tRNA,transposase,head,integrase,terminase,portal,tail,capsid,protease

attL 1954966:1955025|attR 2031140:2033338

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ23362.1\|1912228_1912531_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase GatCAB subunit C	NA	NA	NA	NA
AWQ23363.1\|1912896_1914435_+	sodium/proline symporter PutP	NA	NA	NA	NA
AWQ23364.1\|1914523_1915723_-	CamS family sex pheromone protein	NA	NA	NA	NA
AWQ23365.1\|1915735_1917739_-	DNA ligase (NAD(+)) LigA	A0A0K2QQN8	Ralstonia_phage	5.8e-114	36.1
AWQ23366.1\|1917742_1919935_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
AWQ23367.1\|1919931_1920624_-	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
AWQ23368.1\|1920795_1921098_-	hypothetical protein	NA	NA	NA	NA
AWQ23369.1\|1921206_1922502_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
AWQ23370.1\|1923361_1924528_+\|protease	cysteine protease staphopain A	NA	NA	NA	NA
AWQ23371.1\|1924558_1924885_+	staphostatin A	NA	NA	NA	NA
AWQ23372.1\|1926432_1926606_-	NETI motif-containing protein	NA	NA	NA	NA
AWQ23373.1\|1926586_1927189_-	DUF2179 domain-containing protein	NA	NA	NA	NA
AWQ23374.1\|1927459_1928281_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	7.9e-70	53.1
AWQ23375.1\|1928273_1929743_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	3.5e-108	45.1
AWQ23376.1\|1929926_1931003_+	nitric oxide synthase oxygenase	NA	NA	NA	NA
AWQ23377.1\|1931022_1931817_+	ACT domain-containing protein	NA	NA	NA	NA
AWQ23378.1\|1931888_1931996_+	hypothetical protein	NA	NA	NA	NA
AWQ23379.1\|1932006_1933569_-	SLC13 family permease	NA	NA	NA	NA
AWQ23380.1\|1933773_1934871_-	pectate lyase	U5PWM6	Bacillus_phage	1.6e-46	34.3
AWQ23381.1\|1935242_1935803_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
AWQ23382.1\|1935855_1936785_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
AWQ23383.1\|1936979_1937153_-	hypothetical protein	NA	NA	NA	NA
AWQ23384.1\|1937204_1938584_+	aldehyde dehydrogenase	NA	NA	NA	NA
AWQ23385.1\|1938703_1939732_-	hypothetical protein	NA	NA	NA	NA
AWQ23386.1\|1940001_1940403_+	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
AWQ23387.1\|1940459_1940633_-	hypothetical protein	NA	NA	NA	NA
AWQ23388.1\|1941083_1942124_+	linear amide C-N hydrolase	NA	NA	NA	NA
AWQ23389.1\|1942180_1943023_-	hypothetical protein	NA	NA	NA	NA
AWQ23390.1\|1943019_1943577_-	DUF1700 domain-containing protein	NA	NA	NA	NA
AWQ23391.1\|1943636_1944161_-	hypothetical protein	NA	NA	NA	NA
AWQ23392.1\|1944281_1944845_+	thioredoxin family protein	NA	NA	NA	NA
AWQ23393.1\|1944910_1945651_-	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
AWQ23394.1\|1945650_1946523_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
AWQ23395.1\|1946519_1947200_-	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
AWQ23396.1\|1947200_1948097_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	6.5e-17	30.2
AWQ23397.1\|1948093_1948474_-	GntR family transcriptional regulator	NA	NA	NA	NA
AWQ23398.1\|1948750_1948909_-	hypothetical protein	NA	NA	NA	NA
AWQ23399.1\|1949151_1949250_-	hypothetical protein	NA	NA	NA	NA
AWQ23400.1\|1949449_1950736_+	hypothetical protein	NA	NA	NA	NA
AWQ23401.1\|1951014_1953063_-	MAP domain-containing protein	NA	NA	NA	NA
AWQ23402.1\|1953448_1953649_+	hypothetical protein	A0A1P8L6A7	Staphylococcus_phage	1.0e-26	98.5
AWQ23403.1\|1954020_1954200_+	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
AWQ23404.1\|1954223_1954532_+	hypothetical protein	M9NTD8	Staphylococcus_phage	2.1e-39	100.0
AWQ23405.1\|1954510_1954771_+	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
1954966:1955025	attL	NA	NA	NA	NA
AWQ23406.1\|1955087_1956323_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	3.3e-104	49.1
AWQ23407.1\|1956334_1957102_+	AAA family ATPase	A0A059NT77	Lactococcus_phage	6.3e-53	44.6
AWQ23408.1\|1958059_1958509_+	chemotaxis inhibitory protein	A7TWR9	Staphylococcus_phage	1.5e-78	100.0
AWQ23409.1\|1958803_1959058_-	amidase	Q4ZCK0	Staphylococcus_virus	3.4e-11	90.7
AWQ23410.1\|1958984_1959140_+	amidase	NA	NA	NA	NA
AWQ23411.1\|1959587_1960079_-	kinase	A7TWR8	Staphylococcus_phage	8.0e-86	100.0
AWQ23412.1\|1960269_1961025_-	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
AWQ23413.1\|1961036_1961291_-\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
AWQ23414.1\|1961342_1961450_+	hypothetical protein	NA	NA	NA	NA
AWQ23415.1\|1961502_1961679_-\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	6.5e-22	96.6
AWQ23416.1\|1961830_1962127_-	DUF2951 domain-containing protein	D2JLG2	Staphylococcus_phage	2.9e-46	100.0
AWQ23417.1\|1962184_1962472_-	hypothetical protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
AWQ23418.1\|1962518_1962671_-	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
AWQ23419.1\|1962660_1966446_-	hypothetical protein	A0A1X9H0H3	Staphylococcus_phage	0.0e+00	98.5
AWQ23420.1\|1966461_1967946_-\|tail	phage tail protein	A0A2I6PDJ0	Staphylococcus_phage	3.4e-297	99.8
AWQ23421.1\|1967942_1972472_-\|tail	phage tail tape measure protein	A0A2I6PDK2	Staphylococcus_phage	0.0e+00	99.9
AWQ23422.1\|1972716_1973067_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
AWQ23423.1\|1973116_1973341_-	hypothetical protein	A0A075LYE8	Staphylococcus_phage	3.0e-32	100.0
AWQ23424.1\|1973382_1974027_-\|tail	phage tail protein	A0A2I6PDI6	Staphylococcus_phage	1.1e-119	100.0
AWQ23425.1\|1974027_1974435_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
AWQ23426.1\|1974431_1974836_-	hypothetical protein	A0A2I6PDJ6	Staphylococcus_phage	4.3e-69	100.0
AWQ23427.1\|1974832_1975195_-\|head,tail	phage head-tail adapter protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
AWQ23428.1\|1975178_1975463_-\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
AWQ23429.1\|1975452_1975737_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
AWQ23430.1\|1975756_1976902_-\|capsid	phage major capsid protein	A0A1X9H072	Staphylococcus_phage	5.6e-215	100.0
AWQ23431.1\|1976925_1977663_-\|protease	Clp protease ClpP	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
AWQ23432.1\|1977646_1978834_-\|portal	phage portal protein	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
AWQ23433.1\|1978849_1980511_-\|terminase	terminase large subunit	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
AWQ23434.1\|1980507_1980852_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
AWQ23435.1\|1980982_1981282_-	HNH endonuclease	A0EWY8	Staphylococcus_phage	4.6e-52	100.0
AWQ23436.1\|1981513_1981930_-	transcriptional regulator	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
AWQ23437.1\|1981957_1982158_-	DUF1514 domain-containing protein	D2JLD9	Staphylococcus_phage	1.4e-28	100.0
AWQ23438.1\|1982157_1982808_-	hypothetical protein	D2JLD8	Staphylococcus_phage	2.0e-116	99.5
AWQ23439.1\|1982966_1983116_-	transcriptional regulator	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
AWQ23440.1\|1983112_1983499_-	hypothetical protein	A7TWI1	Staphylococcus_phage	2.0e-63	98.4
AWQ23441.1\|1983495_1983702_-	DUF1381 domain-containing protein	A0A2I6PDB6	Staphylococcus_phage	1.9e-28	95.6
AWQ23442.1\|1983738_1984272_-	dUTP pyrophosphatase	A0A059T5A7	Staphylococcus_phage	3.5e-95	99.4
AWQ23443.1\|1984264_1984513_-	DUF1024 domain-containing protein	C8CH04	Staphylococcus_phage	2.0e-37	97.6
AWQ23444.1\|1984527_1984770_-	hypothetical protein	A0A1P8L6E3	Staphylococcus_phage	3.0e-41	100.0
AWQ23445.1\|1984773_1985142_-	hypothetical protein	A0A0E3XD52	Staphylococcus_phage	6.7e-53	100.0
AWQ23446.1\|1985154_1985559_-	RusA family crossover junction endodeoxyribonuclease	A0A0E3XBN4	Staphylococcus_phage	1.4e-72	100.0
AWQ23447.1\|1985567_1985786_-	hypothetical protein	A0A2I6PDG4	Staphylococcus_phage	1.0e-37	100.0
AWQ23448.1\|1985792_1986677_-	DnaD domain protein	A0A1W6JPN9	Staphylococcus_phage	1.7e-139	100.0
AWQ23449.1\|1986706_1987177_-	single-stranded DNA-binding protein	A0EWX3	Staphylococcus_phage	7.4e-81	100.0
AWQ23450.1\|1987177_1987795_-	MBL fold metallo-hydrolase	S4SWA4	Staphylococcus_phage	4.5e-86	99.4
AWQ23451.1\|1987875_1988796_-	recombinase	A0A2I6PDH5	Staphylococcus_phage	2.3e-166	100.0
AWQ23452.1\|1988797_1990741_-	ATPase	A0A0E3T8H3	Staphylococcus_phage	0.0e+00	98.9
AWQ23453.1\|1990749_1991013_-	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
AWQ24273.1\|1991021_1991282_-	DUF1108 domain-containing protein	A0EWW8	Staphylococcus_phage	8.9e-44	100.0
AWQ23454.1\|1991262_1991589_-	DUF2482 domain-containing protein	W5RAK4	Staphylococcus_phage	1.2e-53	100.0
AWQ23455.1\|1991683_1991845_-	DUF1270 domain-containing protein	D2JGJ6	Staphylococcus_phage	4.3e-20	100.0
AWQ23456.1\|1991841_1992162_-	DUF771 domain-containing protein	A0A2I6PDH6	Staphylococcus_phage	1.5e-56	100.0
AWQ23457.1\|1992220_1992853_+	hypothetical protein	A7TW95	Staphylococcus_phage	1.5e-113	100.0
AWQ23458.1\|1992867_1993008_-	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	1.9e-16	100.0
AWQ23459.1\|1993038_1993236_-	hypothetical protein	A0A1W6JPV3	Staphylococcus_phage	1.2e-24	100.0
AWQ23460.1\|1993251_1994001_-	oxidoreductase	Q8SDM9	Staphylococcus_phage	4.4e-136	99.6
AWQ23461.1\|1994057_1994597_+	hypothetical protein	A7TW92	Staphylococcus_phage	2.2e-97	99.4
AWQ23462.1\|1994620_1994881_-	transcriptional regulator	A7TW91	Staphylococcus_phage	2.7e-40	100.0
AWQ23463.1\|1994928_1995141_-	XRE family transcriptional regulator	A7TWF1	Staphylococcus_phage	1.6e-30	100.0
AWQ23464.1\|1995292_1996024_+	XRE family transcriptional regulator	A0A075LYE4	Staphylococcus_phage	9.8e-88	75.8
AWQ23465.1\|1996177_1996363_+	hypothetical protein	A0A2I6PDS4	Staphylococcus_phage	2.3e-25	100.0
AWQ23466.1\|1996562_1996730_+	hypothetical protein	Q4ZDJ4	Staphylococcus_virus	1.7e-24	100.0
AWQ23467.1\|1996869_1997574_+	hypothetical protein	U5U4R0	Staphylococcus_phage	6.7e-126	99.6
AWQ23468.1\|1997766_1998804_+\|integrase	site-specific integrase	Q38086	Staphylococcus_phage	2.2e-178	99.7
AWQ23469.1\|1999922_2000939_-	bi-component leukocidin LukGH subunit G	A0A2I6PER8	Staphylococcus_phage	3.9e-26	29.3
AWQ23470.1\|2000960_2002013_-	bi-component leukocidin LukGH subunit H	A0A2I6PDF3	Staphylococcus_phage	1.3e-35	32.1
AWQ23471.1\|2002447_2003671_+	succinyl-diaminopimelate desuccinylase	NA	NA	NA	NA
AWQ23472.1\|2004095_2004887_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
AWQ23473.1\|2004948_2005860_-	ferrichrome ABC transporter substrate-binding protein	NA	NA	NA	NA
AWQ23474.1\|2006020_2007328_+	TrkH family potassium uptake protein	NA	NA	NA	NA
AWQ23475.1\|2008441_2009377_+	permease	NA	NA	NA	NA
AWQ23476.1\|2010231_2010459_-	DUF3102 domain-containing protein	A0A2H4JAH5	uncultured_Caudovirales_phage	1.9e-13	47.4
AWQ23477.1\|2010877_2011582_+	toxin	NA	NA	NA	NA
AWQ23478.1\|2011736_2012306_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	3.5e-101	98.4
AWQ23479.1\|2012302_2012644_-	pathogenicity island protein	A0A1W6JQM3	Staphylococcus_phage	1.7e-58	100.0
AWQ23480.1\|2012646_2013174_-\|coat	spore coat protein	A0A1W6JQH7	Staphylococcus_phage	2.3e-86	96.6
AWQ23481.1\|2013224_2013443_-	hypothetical protein	NA	NA	NA	NA
AWQ23482.1\|2013460_2014039_-	pathogenicity island protein	A0A2H4JBG0	uncultured_Caudovirales_phage	1.4e-28	38.4
AWQ23483.1\|2014050_2014392_-	pathogenicity island protein	Q4ZE66	Staphylococcus_phage	7.1e-57	98.2
AWQ23484.1\|2014927_2015569_-	pathogenicity island protein	Q4ZE67	Staphylococcus_phage	3.5e-113	94.8
AWQ23485.1\|2015565_2015946_-	hypothetical protein	Q4ZE71	Staphylococcus_phage	6.9e-69	100.0
AWQ23486.1\|2016257_2017967_-	DUF927 domain-containing protein	Q4ZE73	Staphylococcus_phage	0.0e+00	100.0
AWQ23487.1\|2017980_2018850_-	mobile element-associated protein	Q4ZE74	Staphylococcus_phage	6.0e-169	99.3
AWQ23488.1\|2018913_2019231_-	DUF1474 domain-containing protein	A0A1W6JQH0	Staphylococcus_phage	1.6e-18	58.2
AWQ23489.1\|2019231_2019615_-	pathogenicity island protein	A0A1W6JQI7	Staphylococcus_phage	9.7e-63	96.1
AWQ23490.1\|2019616_2019820_-	pathogenicity island protein	A0A1W6JQF4	Staphylococcus_phage	7.5e-30	97.0
AWQ23491.1\|2019804_2019960_-	pathogenicity island protein	NA	NA	NA	NA
AWQ23492.1\|2019956_2020274_-	helix-turn-helix domain-containing protein	A0A1W6JQE0	Staphylococcus_phage	9.2e-51	98.1
AWQ23493.1\|2020278_2020497_-	XRE family transcriptional regulator	A0A2H4JB11	uncultured_Caudovirales_phage	1.3e-19	66.7
AWQ23494.1\|2020669_2021344_+	XRE family transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	1.6e-39	45.8
AWQ23495.1\|2021357_2022530_+\|integrase	site-specific integrase	A0A1W6JQD3	Staphylococcus_phage	3.5e-220	98.2
AWQ23496.1\|2022598_2024215_-	molecular chaperone GroEL	A0A240F779	uncultured_virus	5.8e-157	54.7
AWQ23497.1\|2024290_2024575_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
2031140:2033338	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP028469

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

15704 : 24615

Staphylococcus_phage(57.14%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ24314.1\|15704_17351_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	5.0e-289	98.2
AWQ24315.1\|17713_19894_-	cadmium-transporting ATPase	E4ZFI9	Streptococcus_phage	9.3e-251	63.7
AWQ24316.1\|19886_20252_-	ArsR family transcriptional regulator	E4ZFI8	Streptococcus_phage	8.5e-24	47.8
AWQ24317.1\|20489_20867_-\|transposase	transposase	NA	NA	NA	NA
AWQ24318.1\|20961_21636_+\|transposase	IS6-like element ISSau6 family transposase	A0A0N9RU54	Staphylococcus_phage	4.8e-113	87.9
AWQ24319.1\|21670_21883_-	hypothetical protein	NA	NA	NA	NA
AWQ24320.1\|22598_22913_+	ArsR family transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	4.7e-39	73.1
AWQ24321.1\|22912_24202_+	arsenical efflux pump membrane protein ArsB	A0A2H4PQU3	Staphylococcus_phage	6.6e-188	81.4
AWQ24322.1\|24219_24615_+	protein ArsC	A0A2H4PQT9	Staphylococcus_phage	8.5e-62	86.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP028468

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP028469

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection