CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP020651	Bordetella bronchiseptica strain D755 chromosome, complete genome	10 crisprs	csa3,DEDDh,DinG,cas3	2	0	2	0

1. CP020651

CRISPR-Cas detection and classification

Crispr_ID: CP020651_1

• CRISPR_ID: CP020651_1
• CRISPR_location: 487499-487600
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP020651_1

Consensus_repeat	Method
CTGCGGCCAGGGAGCCTGTCCCCGC	CRISPRCasFinder

spacers of CP020651_1

>1.1|487524|52|CP020651|CRISPRCasFinder
CGGGGGAGCGACACCTGCGGCCAGGGAGCCTGTCCCCGCCGGGGAGCGACAT

CRISPR arrays and Neighbor proteins around CP020651_1

CRISPR arrays

The CRISPR arrays of CP020651_1

>merge|CP020651|1|487499-487600|CRISPRCasFinder
CTGCGGCCAGGGAGCCTGTCCCCGCCGGGGGAGCGACACCTGCGGCCAGGGAGCCTGTCCCCGCCGGGGAGCGACATCTGCGGCCAGGGAGCCTGTCCCCGC

>CP020651|1|1|487499-487600|CRISPRCasFinder
CTGCGGCCAGGGAGCCTGTCCCCGC	CGGGGGAGCGACACCTGCGGCCAGGGAGCCTGTCCCCGCCGGGGAGCGACAT
CTGCGGCCAGGGAGCCTGTCCCCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP020651.1|AWP82989.1|479691_486822_+|autotransporter-outer-membrane-beta-barrel-domain-containing-protein	unknown	unknown	gnl|CDD|185219
CP020651.1|AWP82996.1|492416_493397_+|hypothetical-protein	unknown	unknown	gnl|CDD|270296
CP020651.1|AWP82987.1|479151_479313_+|hypothetical-protein	unknown	unknown	unknown
CP020651.1|AWP82992.1|488872_490447_+|long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|223395
CP020651.1|AWP82990.1|486855_487455_+|ureidoglycolate-hydrolase	unknown	unknown	gnl|CDD|380432
CP020651.1|AWP82982.1|469284_470430_-|alanine-racemase	unknown	unknown	gnl|CDD|143487
CP020651.1|AWP82995.1|492027_492363_+|alkylhydroperoxidase	unknown	unknown	gnl|CDD|223672
CP020651.1|AWP82994.1|491218_491983_+|enoyl-CoA-hydratase	unknown	unknown	gnl|CDD|119339
CP020651.1|AWP82988.1|479344_479476_+|entericidin	unknown	unknown	gnl|CDD|227797
CP020651.1|AWP82984.1|471207_472116_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176168
CP020651.1|AWP87145.1|496488_496965_+|dehydratase	unknown	unknown	gnl|CDD|239535
CP020651.1|AWP82986.1|472608_479067_+|autotransporter-outer-membrane-beta-barrel-domain-containing-protein	unknown	unknown	gnl|CDD|273608
CP020651.1|AWP82991.1|487881_488859_+|hypothetical-protein	unknown	unknown	gnl|CDD|270234
CP020651.1|AWP82983.1|470456_471116_-|haloacid-dehalogenase	unknown	unknown	gnl|CDD|319787
CP020651.1|AWP82981.1|468808_469144_-|hypothetical-protein	unknown	unknown	gnl|CDD|377831
CP020651.1|AWP82999.1|495373_496336_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176131
CP020651.1|AWP82993.1|490454_491195_+|transcriptional-regulator	unknown	unknown	gnl|CDD|224332
CP020651.1|AWP82997.1|493496_494051_+|hypothetical-protein	unknown	unknown	gnl|CDD|176248
CP020651.1|AWP82985.1|472112_472295_+|integrase	unknown	unknown	gnl|CDD|371934
CP020651.1|AWP82998.1|494142_495396_+|CoA-transferase	unknown	unknown	gnl|CDD|367110

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP020651.1|AWP82989.1|479691_486822_+|autotransporter-outer-membrane-beta-barrel-domain-containing-protein	gnl|CDD|185219	PRK15319, PRK15319, fibronectin-binding autotransporter adhesin ShdA.	1.64461e-42
CP020651.1|AWP82996.1|492416_493397_+|hypothetical-protein	gnl|CDD|270296	cd13578, PBP2_Bug27, Aromatic solutes transporter of Bug (Bordetella uptake gene) protein family; contains the type 2 periplasmic binding fold. Bug27 binds non-carboxylated solute nicotinamide, in contrast to BugD (aspartic acid transporter) and BugE (glutamate transporter) which both bind aliphatic carboxylated ligands. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) receptors present in a number of bacterial species, but mainly in proteobacteria. Bug proteins are the PBP components of the tripartite carboxylate transporters (TTT). Their expansive expansion in proteobacteria indicates a large functional diversity.	7.38592e-131
CP020651.1|AWP82992.1|488872_490447_+|long-chain-fatty-acid--CoA-ligase	gnl|CDD|223395	COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	5.01509e-133
CP020651.1|AWP82990.1|486855_487455_+|ureidoglycolate-hydrolase	gnl|CDD|380432	cd20298, cupin_UAH, ureidoglycolate amidohydrolase (UAH) and related proteins, cupin domain. This family includes the cupin-fold protein, ureidoglycolate hydrolase (AllA; EC 3.5.3.19), which is involved in the breakdown of allantoin under aerobic conditions. Allantoin is the key intermediate of nitrogen fixation in bacteria, and its degradation occurs in several steps. AllA is involved in the third step of this pathway which consists of hydrolysis of (S)-ureidoglycolate to yield glyoxylate, ammonia, and CO2. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.23299e-15
CP020651.1|AWP82982.1|469284_470430_-|alanine-racemase	gnl|CDD|143487	cd06812, PLPDE_III_DSD_D-TA_like_1, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes Similar to D-Serine Dehydratase and D-Threonine Aldolase, Unknown Group 1. This subfamily is composed of uncharacterized bacterial proteins with similarity to eukaryotic D-serine dehydratases (DSD) and D-threonine aldolases (D-TA). DSD catalyzes the dehydration of D-serine to aminoacrylate, which is rapidly hydrolyzed to pyruvate and ammonia. D-TA reversibly catalyzes the aldol cleavage of D-threonine into glycine and acetaldehyde, and the synthesis of D-threonine from glycine and acetaldehyde. DSD and D-TA are fold type III PLP-dependent enzymes, similar to bacterial alanine racemase (AR), which contains an N-terminal PLP-binding TIM barrel domain and a C-terminal beta-sandwich domain. AR exists as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Based on their similarity to AR, it is possible members of this family also form dimers in solution.	0
CP020651.1|AWP82995.1|492027_492363_+|alkylhydroperoxidase	gnl|CDD|223672	COG0599, COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown].	1.70453e-16
CP020651.1|AWP82994.1|491218_491983_+|enoyl-CoA-hydratase	gnl|CDD|119339	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.	6.87831e-58
CP020651.1|AWP82988.1|479344_479476_+|entericidin	gnl|CDD|227797	COG5510, COG5510, Predicted small secreted protein [Function unknown].	1.86823e-05
CP020651.1|AWP82984.1|471207_472116_+|LysR-family-transcriptional-regulator	gnl|CDD|176168	cd08479, PBP2_CrgA_like_9, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 9. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.49194e-92
CP020651.1|AWP87145.1|496488_496965_+|dehydratase	gnl|CDD|239535	cd03451, FkbR2, FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2 has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. The function of FkbR2 is unknown.	1.58721e-71
CP020651.1|AWP82986.1|472608_479067_+|autotransporter-outer-membrane-beta-barrel-domain-containing-protein	gnl|CDD|273608	TIGR01414, Contains:_AIDA-I_translocator, outer membrane autotransporter barrel domain. A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	6.72849e-45
CP020651.1|AWP82991.1|487881_488859_+|hypothetical-protein	gnl|CDD|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	8.51184e-99
CP020651.1|AWP82983.1|470456_471116_-|haloacid-dehalogenase	gnl|CDD|319787	cd02588, HAD_L2-DEX, L-2-haloacid dehalogenase. L-2-Haloacid dehalogenase catalyzes the hydrolytic dehalogenation of L-2-haloacids to produce the corresponding D-2-hydroxyacids with an inversion of the C2-configuration. 2-haloacid dehalogenases are of interest for their potential to degrade recalcitrant halogenated environmental pollutants and their use in the synthesis of industrial chemicals. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.90626e-33
CP020651.1|AWP82981.1|468808_469144_-|hypothetical-protein	gnl|CDD|377831	pfam07411, DUF1508, Domain of unknown function (DUF1508). This family represents a series of bacterial domains of unknown function of around 50 residues in length. Members of this family are often found as tandem repeats and in some cases represent the whole protein. All member proteins are described as being hypothetical.	1.7869e-18
CP020651.1|AWP82999.1|495373_496336_-|LysR-family-transcriptional-regulator	gnl|CDD|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.47076e-59
CP020651.1|AWP82993.1|490454_491195_+|transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	4.17717e-46
CP020651.1|AWP82997.1|493496_494051_+|hypothetical-protein	gnl|CDD|176248	cd08288, MDR_yhdh, Yhdh putative quinone oxidoreductases. Yhdh putative quinone oxidoreductases (QOR). QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.86669e-58
CP020651.1|AWP82985.1|472112_472295_+|integrase	gnl|CDD|371934	pfam12167, Arm-DNA-bind_2, Arm DNA-binding domain. This domain is found at the N-terminus of various phage integrases. The domain binds to DNA.	5.99489e-08
CP020651.1|AWP82998.1|494142_495396_+|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	5.83088e-144

Protein sequences

>CP020651.1|AWP82990.1|486855_487455_+|ureidoglycolate-hydrolase
MRLYWRMPTTTPALRPQVLTEAAFAPYGWMLGKPLPAGDDVPRFSNPATDFWQEHVFDTGVGAGRETEVLWVNYRVSQPGFDTLEKHLLTQQAIVPLTGAIVQIVARSAFDGSPDLASLAAFVVPPGQGICMRPGCWHATRISGGEVTCLMLTRRSTTLDLVRHLHGEPARESEIVAIVPHGLDLPARPTTEGPSPHGR
>CP020651.1|AWP82989.1|479691_486822_+|autotransporter-outer-membrane-beta-barrel-domain-containing-protein
MIAGVSSHWQASWEDYEFLSGFRRHARVRPLTASDRHGRTDQFAAWPLHPSCFIHKPYQRRGVIPACAHTFHFAGEIMRRLKAQAFEGRRSRPAGHGVAPTLLALALGFQGTAAWANCTTSGSSTTCTAAGGAHGATVGGGSTGHNKQVTVQAGARIEAGDKAAISVGNNSQVQIQGGAVVQSTVNTAASGQYAKTLEAASNNNISIQEGAQLLAKGSASQSSALGLSGAGNTVTNRGTIRADNAAAIWVTANTAGANTIDNYGTIETVLNGGYANAIGSTRNNNATGAGVTVRNHANGRIVGNVKFEAGDDSVILDGGSTITGSLNGGSGNNSLTLKAGDGTLGRAIRNFGTITKQEAGTWTLNGQVGRNDNNLKSTVKVEGGTLALRGDNSGATQGGVLQVSAGATADVTAASAMQSISNAGTVQFTQDSNAAYAGVLSGTGSIVKRGGGDLTLTGNNTHTGKVVVEAGSLSVSAANNLGGAGSSVQLKGGALALKKTIAVNRGLTLDSGAQTLIIEPGTTTTWQGQVSGAGKLVTQGGTLVLEHASNTYSGGTEINNGTLRAAHDASLGSGTLALKNSQLAATDSFTATRALTLAGNESIDVAATKILSWNGEISGAGTLVKEGQGTLLLRGTNQQNGGTTVNAGTLQISRDANLGRGALALNDGTLQSTGSFATSRAATLRGQATMEVDASHTVTWNGELSGGGMLRKSGQGTLALAGANTYSGGTVVEAGALRAGHEDNLGRGAITLQGGDLLAGGSFSSNRDLTLVRGSLDVARDVTLTWSGAISGAGDLVKTGDGTLALTGVNEYAGQTVLRQGKLRVAREESLGGGALVLENNTVFESAGSYAIGRRVTLKGAPKVATPAGDTLEWRGTVDGDGKLYKQGGGTLVLSGNNTYAKGVEVWGGVVQVSRDQNLGAANGAVTLNGGGLAANGDFTSNRQLELTAGAKAIDVAAGKDVTWRGVVNGAGALTKAGDGTLRLEGVNTYTGGTRLQGGTVQVSRDNNLGQAAGAVTFDGGRLASTGSFATARAATLNNAGQIDTAQGTTLTWNGAIGGKGELRKQGAGTLVLGGANTYQGDTRVEAGTLQVSADANLGQGAVHLHDSRLATTGTFATSRRLELTGRGTVQAAAAATLDWRGTVAGAGTLVKEGAGTLVLAGDNQHAGGTEVRAGTLQVSRATNLGPGALALENAALATTASFTATQAATLTGNAAIDTAAGTTLGWEGAIGGTGSLHKKGEGKLVLVKDNHHDGGTTIHAGTLQVSRDANLGSGQSAVTLDGGALAVSAGFSSGREIVVGAGHGALSVAGGHTLQWQGQVGGAGTLTKTGDGTLVLEHDNTHAGGTRVTGGVLRVSRDENLGEAHGMLTLDGGTLSATAGFASRRNATVGNGGGRIVVADSATLDLQGDVAGAGRLVKEGAGTLALGGTNTYAGGTVVEAGTLRVARDANLGGGALTLNNSRLHATAGFATGRDATLTGRASIDTDNRATLQWRGTVDGAGTLVKQGAGTLVLDGDNRYAGGTEVNAGTLQVARDANLGAGDVALNGSRLAATASFATARTATLSGAAAIDTADGATLDWNGLLDGDGALVKQGNGTLALAAANRYGGGTIVKAGAVRIARDANLGRAGTGVTLDGGALATTADLATGRAATLGAAHGTLDVAAGTRLDWNGAIGGAGALTKTGAGTLALNHDNQHAGGTLVHGGTLRIARDANLGAAGTAVTLDGGTLATTASLALDRALRVGARNGVLLPDAGTTLDWRGVVAGAGKLTKAGPGMLVLSADNRHGGGTAVTGGTLQVSRDANLGAAAGALTLDGGTLLSTASFASARAATLDAAGGTFVTRDGTRLDWDGAIGGAGGLVKEGAGELRLGNANTYQGPTRIAAGRLAVNGSIASPVTVEQAGVLGGTGRIVGDVANRGVVAPGNSIGALTVAGNYAGTGGSLEVEAVLGGDAVPADRLVLDGGAASGVTPVVVKPQGGVGGLTLRGIPVVVAQGGATTAPGAFRLAQPLVAGAYEYQLLRGAGDGAAAQAQDWYLRTSRVERDKAGRIVKVVPFYRPEVALYAGTPMLMRMTGTEMLGSYRERAGQTGAVSPEAGATAARGGWARTFGRRFERSAGGEAAPSFDGHLAGAQLGADLYARSSATRHTDAFGVFGGYATVRGDVHGLARGEIQAVGTSTLRATQLGAYWTHTGPGGWYIDTVLAGTRYRQQTKSSAQVGAVSRGWGMTASVEAGYPWQLNPRWRIEPQAQVVYQQLGIANGADRVSTVSYKTPDALTARLGTRLSGQYAYGKAQLRPFMGVSLLHDFTGADTVTFAGAHGVRASRQNTAVDLKAGVDTQLGKSVGLWGQVGYGKSVGSGDGSDRGWSANLGLRVAY
>CP020651.1|AWP82988.1|479344_479476_+|entericidin
MNNRIRAALLAAITLVALAGCNTMSGAGKDIERGGEKIQEKAQ
>CP020651.1|AWP82987.1|479151_479313_+|hypothetical-protein
MGAQADRLHGKRYECAFLPTEEDNMKTCIHVLAAVSGDVRDQHETDAEMRDGK
>CP020651.1|AWP82986.1|472608_479067_+|autotransporter-outer-membrane-beta-barrel-domain-containing-protein
MPQRSQPFNSCTGHSGVRGHGVAPTVLVLALGFHGTAAWANCQTAGSAVTCDASSPNPYTGTVGSGASSGNLTITVGPGARIESGNAHAISVGTGNTISLDGNAQVSNSVTTGGPGNYNAGLNTIEFEHSNTLMIGADARVAAEGTDPAAHAIAFTGRSNAVTNYGTVSSASGAAIWNQFEDDYVNNTIHNYGVIETTANGGDAVVIGSATGNGASGRGMTLYNYAGGRIVGNVVLGEGDDTVRLEAGSTLTGSLDGGAAGTDVLYLEGTSGSGELTQDISNFNEINKIVNGSTWTLAGSLGANSSGKATVVNAYNGELIVTGDNSAATAGSMMTVWAGARLQVNTTSAMAAIQSNGSGVAAFSQQTDGTYAGVLSGSGNFAKEGAGSLTLTGVNTYTGTLQLKEGKVIVSAAENLGGANSMLEFDGGTLNTTSDMTSVRRASIAAGGGTFEVAGGTTLNWTGRVTGNGTLVKEGAGTLALSGFNAHGGTVVNAGTVQISSDYGLGNGALTLNNSRLASTADIYTEAAATVNGNGTFDTANGTTLQWMGDIGGAGALVKTGAGTLLLGGDSLYAGGTVVNAGTVQVFKDASLGGGALTLNNASLASLGSFSTARAATLTGNGTFDTATGTTLGWTGDIGGAGALVKTGQGTLVLGGDNQYGGGTTVNAGAVQVARDANLGAAAGTVALNDARLASTGTFSTARAATLTGNGTFDTATGTTLEWTGDIGGAGALVKTGQGTLVLGGDNQYGGGTTVNAGAVQVARDANLGVAAGTVALNGGTLAASASFSSARGVTIGAGNGAMSVASGASLDWQGLIGGTGALAKEGAGTLVLGNDNQYAGGTVVNAGTVQVARDANLGAAAGAVTLDGGTLAASAGFTSARGVTIGAGNGAMSVASGASLDWQGLIGGTGALIKEGAGTLVLGNDNQYGGGTTVNGGTVQVARDANLGAAAGTVALNDARLASTGTFSTARAATLTGNGTFDTATGTTLGWSGDIGGAGALVKTGQGTLVLGGDNQYAGGTTVNAGAVQVARDANLGAAAGAVALNDARLASTGTFSTARAATLTGNGTFDTADGTTLGWTGDIGGAGALVKTGQGTLVLDGDNQYGGGTTVNAGTVQVSRDANLGAAAGAVALDGGTLAASAGFTSARGVTIGAGNGAMSVASGASLDWQGLIGGTGALAKEGAGTLVLGNDNQYAGGTVVNAGTVQVARDANLGAAAGAVTLDGGTLAASAGFTSARGVTIGAGNGAMSVASGASLDWQGLIGGTGALIKEGAGTLVLGNDNQYGGGTTVNGGTVQVARDANLGAAAGTVALNDARLASTGTFSTARAATLTGNGTFDTATGTTLGWSGDIGGAGALVKTGQGTLVLGGDNQYAGGTTVNAGAVQVARDANLGAAAGAVALNDARLASTGTFSTARAATLTGNGTFDTADGTTLGWTGDIGGAGALVKTGQGTLVLDGDNQYGGGTTVNAGTVQVSRDANLGAAAGAVALNDARLASTGTFSTARAATLTGNGTFDTADGTALGWTGDIGGAGALVKEGLGTLVLDGDNQYGGGTTVNAGTVQVARDANLGAAGGAVRLQGATLASTGSFASARALTLGAAGGTFATLGATTLGWDAAIDGAGGLTKTGAGDLVLSQANTYAGPTLIKEGRLAVNGSIASPVTIDPGGVLGGTGRVLGAVANSGTVAPGNSIGTLTIVGNYAGTGGRLEMEAQLGGDASPADRLVIDGGAATGRTDVVVINQGGLGGQTDQGIPLVVARNGATTTADAFSLASPVAAGAYEYKLLRGTPDGTAANAQNWYLRSGLLVPPAEVPGGGPGGAPEPEFIPFYRPEVALYAGAPMLMRAVGLQALGTYHERTGEQGLMTRDDPDPVRRGAWTRAFGRTFERSGSGDVDPRFDGHVAGLQAGVDLYARRSDQGHADLAGVFGGYANARGHMDGFARGETGAYAGKPDLNAYYIGGYWTHIGPSGWYVDAVLAGTRYEQKAKSSNDLRTEAKGWGVTASVEAGYPVPIGEKWHIEPQAQLVYQRLTVSNGEDDVSSVSYRTPDSVTARLGARLSGQYAYNTTQLRPFMEVSLLRDFAGTDTVTFSGIDRIDSRYQATAVDLTAGLVAQVRKDVGLWGQVGYGKSIGGGDGSDRGWAASLGLRIEY
>CP020651.1|AWP82985.1|472112_472295_+|integrase
MSGKFEGVRPASESSIEISFVYQGRICVRRLRMKPTAANLKRAAEQRAAIVEAIARGEQA
>CP020651.1|AWP82984.1|471207_472116_+|LysR-family-transcriptional-regulator
MLRIEDLQLAAALAQAPSLSAAARALNVTPPALSMRLRKLEAGLGLALAVRSARRLSLTPEGERLAREAAALLAQLQALPESLRRDDSRLTGTLRVAAPFGYGRRHIAPVLARLAQRHPELRVQLDLRETPWPDHQDADAVVHIGAVRDSSWVTRRLADNERWLCASPQYLQDHGMPREPRDLLHHRCICIRENDEDASLWRFRRADAGAAGRKAAETVRIAPAYVSNDGNVARTWAEQGLGLVVRSQWDAEGAVARGALVRVMPQWQLDSAPVMLLVPGRKGRSARVKALLECFDEQAGHA
>CP020651.1|AWP82983.1|470456_471116_-|haloacid-dehalogenase
MSIATPTGYPRAVLFDLLTGLLDSWTAWNAAAGSEPAGRAWRAEYLRLAYGCGRYVPYGQLVRDAARATGLPDGAPAALEANWHELPVWDDARSLLRALRPHCKLAVVTNCSRDLGHQAAGLLGVDWDAVVTAEEAGFYKPDPRPYRMALQALQVPAGDAAFVAGSGHDLFGTAAVGLRTCWHNRLGLARPQGAPEPELQSATLAAALPWLQAFRPAVR
>CP020651.1|AWP82982.1|469284_470430_-|alanine-racemase
MTTTHAHPLDTLDTPAAIVDVARMQHNIARMQDRMNGLGVSLRPHVKTSKCTPVALAQLAAGARGVTVSTLKEAEQFFAAGIADILYAVGMAEHRLPAALALRRRGCDLKIITDNAESARTIADFGRAHDEVFEVWIEIDTDGHRSGIKPEEAALLAVGAALHEGGMRLGGVMTHAGSSYDLDTPEALAAMAEQERAGCVRAAERLRAAGLPCPVVSVGSTPTALSAAQLQGVTEVRAGVYVFFDLVMHNIGVCRVDELALSVLATVIGHQADKGWVIVDAGWMAMSRDRGTQKQKQDFGYGQVCTADGAPLAGYTLIGANQEHGIMAGGPAGEDVTTRFPVGMRLRILPNHACATGAQFPQYHALEADGGLQAWERAHGW
>CP020651.1|AWP82981.1|468808_469144_-|hypothetical-protein
MSGYFVLKASGTQYMFNLHAGNHEIILTSERYTSKASAQDGIASVQKNAPDDARYQRLTAKDGSPYFSLTATNGQSIGRSEMYKTTQARDNGIASVKSNAPGAPTKDQTQA
>CP020651.1|AWP82991.1|487881_488859_+|hypothetical-protein
MYRIVSALAVSVTCLAGMGAAQADQGAAAYPDKPIKIVIPYSAGGGTDQFMRIVSERASRVLGQPITILNKPGGSTVIGVNAVIGAAPDGYTLLVSTNTSYTLIPYVMSPPPYAPEKSLDYVATLGQTSMVLTANKTMPSDLKTVLDSARQSPGRYTYATYGVGSSTHLAGEVFMNDTGVEFRHIPYKGVEAVTALAGNQVDLMIDGINAAGTMLDAGKTQALVVLQRTRSQFLPDTPTLVEAGYPEAAENVISYVMAAPKGTPAAVIDKLQKSFAEALRDPGVLAQAKAMRTEAAFKGPAQTQAFVDSQSALFKDIVAKKNIKF
>CP020651.1|AWP82992.1|488872_490447_+|long-chain-fatty-acid--CoA-ligase
MSSLEQQMQPPGQTWWDIIEAHARRFPERDALAHGDGAITYGELVARVRRCAAGLSARGIGAGDCVALLAPPTPDAMVCLLAAARLGALWVGLNPRYQAREMAYVIGHAQPKLVLSVREFEARRYADDLEAALATLAPQARRPELLYYDSQASCDEAMLHALCDAPDAACPAPFDDAAQPCMLVYTSGTTGNPKGVLLSQTALIYRSTVQARTFATRSHPVVINFAPINHIGGMHFRGLSQILADGTIIYQERYRPAEVMGLIEKHRVNMLMLGSTMLQMLIREPSFDMSIMRGMEWFIFSGAAIPMPILQRVKEHCPRIGSTYGLTESCGSVSYIVASDSLEAAAYTVGRAIPEGQLRVADEQGQPLPAGTQGELQVRGQYCMNGYLRDAAATAGAFTRDGWLKTGDMAQREDDGNFRLVGRIKEMYKSGGYNVYPREIEVVLEQHPNVLMSAVIAVDDELYQQVGHAHLILRPDTEVSEPELVQWCRERMANYKVPKRIFVRNSLPMLSIGKVDKIALRQQH
>CP020651.1|AWP82993.1|490454_491195_+|transcriptional-regulator
MSNPLNRYHHILHAIAGRPGGLSLADLAAATGLPRSTTHRMATTLREIDYLGQDDASGNFVLGDGLIGLMRSSLAQDSKLALFDPALNFVVGRLEETAFCARLWNDEVDLVQAVTPTRKDQLYIYPGVGGRPLDKCSSSKAILAYLDPARIQALLEPLASSTPGLRVDTLMQELDQVHRQGFAICDGEIDEGVLSVACPVMSGPARGLYSIGVVGPAARLKSHDLQEIVEVLHSAADLAAAELLNS
>CP020651.1|AWP82994.1|491218_491983_+|enoyl-CoA-hydratase
MKEIISLEKTGAVATVTIDRGGKRNALSQEMVLRLTDIALQLQQDTSVACIVLSGNQNEFSAGIDLGDATRWSLDDKTQLERRAIALRGTRLCKAWEDLPQITIAAVEGMNVGGGIALTLACDWRVMGKSAFLFVPEVQIGIPLGWQTIPRLVNLVGPARAKQIVLLGEKMSADTALEWGVADFVVADGAACAHAQDLAARIGKMPELAVRMSKQSINAYANALNHLGSHMDVDQAMLCGQTQDAVAVRDRYAR
>CP020651.1|AWP82995.1|492027_492363_+|alkylhydroperoxidase
MLDWNQYRSELMTRIGEIAKASPETVKGYQQLSAAGKQTNQLDAKTRELIALAVAVTTRCDGCIAVHAKAATDNGATKGEIAEALGVAVALNAGAALVYSARVMDAVDAAQ
>CP020651.1|AWP82996.1|492416_493397_+|hypothetical-protein
MSRLARLLLAGCCALGAAAPAGAGNWPAGPVTFIVPFPAGGSMDTFSRPIAGQLSKELGVPVVVSNRSGAGGGVGIAAIARAAPDGYTIGMSSVGNMAINPHIYPDLPYSPLKDFTPIGLAGRFVNVLVVNSKIPARNVQELIELDRKKPGNITFASAGNGSTNHLSGELLKQLTHTSFLHVPYRGSGPALADVVAGNVAFMFDTLNTSMPLIESGALRALAVTSAERSPFLPDVPTMNEAGVAGYAKSGEDLWWAIIAPQGVPADVRDKLNAALNKALGSPALQAQVRAQRVETLTSTPDALQTILRDDYNRWGGIVREAGVKLD
>CP020651.1|AWP82997.1|493496_494051_+|hypothetical-protein
MPCLVRFEESSMFDALLLTQNDDRAIVAQRVQLDEARLPDGDVLVDIAWSTVNYKDALAITGRIPIVRQFPMVPGIDFAGTVLESHDSRHRAGDAVLLDGWGLGQAHWGGLARKARVKADWLVPMPGGMDARRAEAWGRLASELPAEITDANTRAITLDEVVDLAPRLLAGQVRGRVVVDVGAG
>CP020651.1|AWP82998.1|494142_495396_+|CoA-transferase
MQSFYQEPAVAADLKEAPHPPKALSGLRVLDIATFLAAPFCGTIMADFGADVIKIEQPKGGDSLRKFGTPSPCGDTYMWMSEARNKRFVTLDLRTPEGAALFKELVRESDVVLENFRPGTLEKWGLGYDVLSELNPGLILLRVSAYGQDGPKREEPGFARIAHAFGGLAHLAGEPDGPPVVPGSTSLADYISGLWGAIGVLTALQARNHTGLGQVVDIGLYESVFRLLDEIAPVYAATGFVRRRLGADVPNVAPHSHYQTRCGQWVAIACSNDRMFERLASAMGKPELAGDARFATAAARAENRPAINAQVAAWSARFDLQALLDLCRDEGVPCSKVYSIEDIFQDEQYRARGNLMEVDDPRIGKTVLPAPVPRLSGTPARFLRAGGALGQDNAGVFEELLGVCGERLAALRQAGVV
>CP020651.1|AWP82999.1|495373_496336_-|LysR-family-transcriptional-regulator
MGKEKSRPLPNINLKLLHTFMLVAEHCSFRQAAELSHRSQAAVTGQIKQLEAQLGVDLFHRTTRQVRLTAEGTQLLESARRAVHEMENGLRQIQETVDLKRGRIFLSCSTTVSSTRLAPILAAFERDYPGVEVFVRELTSGDMFETVRREEADFGIGPIMELPEFDFEPILTENLYAVVPRNLFPDTAEQITLARLASMPLLLLNPGTALRALIDDTARSRGLTINTKFQFSQAQTLISMATAGLGAAVLPAMVLPAKPHKDVQVLPIASPRMTRDVAIVRLRHRKLTPAAARLAQLVRDLIHGPSGRRTARATTRRPPA
>CP020651.1|AWP87145.1|496488_496965_+|dehydratase
MLLARGRLLEDFKTGDQYAHWPGRTITEADNIQFSLLTMNRHPAHCDHHYASQTEFGKPLVNSGLTLAIVLGMSVDDISANAVANLGWQEIELLAPVHPGDTVYARSQVLSVRESKSRPGQGVVTVRTEGVRADGVVFMRFVRSCLVPSRASLAGARQ

Crispr_ID: CP020651_2

• CRISPR_ID: CP020651_2
• CRISPR_location: 1003987-1004071
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of CP020651_2

Consensus_repeat	Method
GGTGCCTGTCCCCGCGGGGACAG	CRISPRCasFinder

spacers of CP020651_2

>2.1|1004010|39|CP020651|CRISPRCasFinder
ATACCGTCTTGGCAGGCTAGTGTTCATGGCGTATGACAG

CRISPR arrays and Neighbor proteins around CP020651_2

CRISPR arrays

The CRISPR arrays of CP020651_2

>merge|CP020651|2|1003987-1004071|CRISPRCasFinder
GGTGCCTGTCCCCGCGGGGACAGATACCGTCTTGGCAGGCTAGTGTTCATGGCGTATGACAGTGTGCCTGTCCCCGCGGGGACAG

>CP020651|2|2|1003987-1004071|CRISPRCasFinder
GGTGCCTGTCCCCGCGGGGACAG	ATACCGTCTTGGCAGGCTAGTGTTCATGGCGTATGACAG
TGTGCCTGTCCCCGCGGGGACAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP020651.1|AWP83431.1|1002280_1003879_-|inorganic-triphosphatase	unknown	unknown	gnl|CDD|143624
CP020651.1|AWP83441.1|1011755_1012772_+|thiamine-monophosphate-kinase	unknown	unknown	gnl|CDD|235583
CP020651.1|AWP83436.1|1007751_1008579_-|transcriptional-regulator	unknown	unknown	gnl|CDD|224332
CP020651.1|AWP83439.1|1010716_1011244_+|6,7-dimethyl-8-ribityllumazine-synthase	unknown	unknown	gnl|CDD|234606
CP020651.1|AWP83424.1|995378_997898_+|AsmA-family-protein	unknown	unknown	gnl|CDD|236772
CP020651.1|AWP83440.1|1011251_1011716_+|N-utilization-substance-protein-B	unknown	unknown	gnl|CDD|234686
CP020651.1|AWP83430.1|1001028_1002234_+|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl|CDD|236686
CP020651.1|AWP83438.1|1009527_1010703_+|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II	unknown	unknown	gnl|CDD|237587
CP020651.1|AWP83428.1|999808_1000318_-|phosphopantetheine-adenylyltransferase	unknown	unknown	gnl|CDD|234674
CP020651.1|AWP83423.1|994611_994950_-|transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|223713
CP020651.1|AWP83429.1|1000338_1000959_-|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	unknown	unknown	gnl|CDD|223813
CP020651.1|AWP83433.1|1004935_1005826_-|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl|CDD|273441
CP020651.1|AWP83427.1|999502_999754_-|ferredoxin	unknown	unknown	gnl|CDD|319871
CP020651.1|AWP83432.1|1004117_1004939_-|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl|CDD|273441
CP020651.1|AWP83437.1|1008584_1009382_-|HAD-family-hydrolase	unknown	unknown	gnl|CDD|273651
CP020651.1|AWP83425.1|997894_998281_+|hypothetical-protein	unknown	unknown	gnl|CDD|281474
CP020651.1|AWP83434.1|1005822_1006593_-|phosphonates-import-ATP-binding-protein-PhnC	unknown	unknown	gnl|CDD|213223
CP020651.1|AWP83426.1|998288_999506_-|transporter	unknown	unknown	gnl|CDD|281578
CP020651.1|AWP83435.1|1006595_1007603_-|phosphonate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270291
CP020651.1|AWP83422.1|994108_994615_-|polyketide-cyclase	unknown	unknown	gnl|CDD|176905

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP020651.1|AWP83423.1|994611_994950_-|transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	3.6e-19	64.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP020651.1|AWP83431.1|1002280_1003879_-|inorganic-triphosphatase	gnl|CDD|143624	cd07756, CYTH-like_Pase_CHAD, Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain. This subgroup belongs to the CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) superfamily. Members of this superfamily hydrolyze triphosphate-containing substrates, require metal cations as cofactors, and have a unique active site located at the center of an eight-stranded antiparallel beta barrel tunnel (the triphosphate tunnel). A number of proteins in this subgroup also contain a C-terminal CHAD (Conserved Histidine Alpha-helical Domain) domain which may participate in metal chelation or act as a phosphor-acceptor. The name CYTH originated from the gene designation for bacterial class IV adenylyl cyclases (CyaB) and from thiamine triphosphatase. Class IV adenylate cyclases catalyze the conversion of ATP to 3',5'-cyclic AMP (cAMP) and PPi. Thiamine triphosphatase is a soluble cytosolic enzyme which converts thiamine triphosphate to thiamine diphosphate. This domain superfamily also contains RNA triphosphatases, membrane-associated polyphosphate polymerases, tripolyphosphatases, nucleoside triphosphatases, nucleoside tetraphosphatases and other proteins with unknown functions. Proteins of this subgroup have not been characterized.	5.26778e-56
CP020651.1|AWP83441.1|1011755_1012772_+|thiamine-monophosphate-kinase	gnl|CDD|235583	PRK05731, PRK05731, thiamine monophosphate kinase; Provisional.	1.95453e-132
CP020651.1|AWP83436.1|1007751_1008579_-|transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	9.15813e-52
CP020651.1|AWP83439.1|1010716_1011244_+|6,7-dimethyl-8-ribityllumazine-synthase	gnl|CDD|234606	PRK00061, ribH, 6,7-dimethyl-8-ribityllumazine synthase; Provisional.	4.04555e-65
CP020651.1|AWP83424.1|995378_997898_+|AsmA-family-protein	gnl|CDD|236772	PRK10833, PRK10833, putative assembly protein; Provisional.	2.80816e-30
CP020651.1|AWP83440.1|1011251_1011716_+|N-utilization-substance-protein-B	gnl|CDD|234686	PRK00202, nusB, transcription antitermination factor NusB.	1.22823e-51
CP020651.1|AWP83430.1|1001028_1002234_+|signal-recognition-particle-docking-protein-FtsY	gnl|CDD|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	2.49182e-175
CP020651.1|AWP83438.1|1009527_1010703_+|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II	gnl|CDD|237587	PRK14019, PRK14019, bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II.	0
CP020651.1|AWP83428.1|999808_1000318_-|phosphopantetheine-adenylyltransferase	gnl|CDD|234674	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional.	3.03384e-101
CP020651.1|AWP83423.1|994611_994950_-|transcriptional-regulator	gnl|CDD|223713	COG0640, ArsR, Predicted transcriptional regulators [Transcription].	2.51065e-15
CP020651.1|AWP83429.1|1000338_1000959_-|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	gnl|CDD|223813	COG0742, COG0742, N6-adenine-specific methylase [DNA replication, recombination, and repair].	1.53382e-57
CP020651.1|AWP83433.1|1004935_1005826_-|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl|CDD|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	2.14802e-90
CP020651.1|AWP83427.1|999502_999754_-|ferredoxin	gnl|CDD|319871	cd10549, MtMvhB_like, Uncharacterized polyferredoxin-like protein. This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.	1.53234e-06
CP020651.1|AWP83432.1|1004117_1004939_-|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl|CDD|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	1.08607e-97
CP020651.1|AWP83437.1|1008584_1009382_-|HAD-family-hydrolase	gnl|CDD|273651	TIGR01484, Putative_mannosyl-3-phosphoglycerate_phosphatase, HAD-superfamily hydrolase, subfamily IIB. This subfamily falls within the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The Class II subfamilies are characterized by a domain that is located between the second and third conserved catalytic motifs of the superfamily domain. The IIB subfamily is distinguished from the IIA subfamily (TIGR01460) by homology and the predicted secondary structure of this domain by PSI-PRED. The IIB subfamily's Class II domain has the following predicted structure: Helix-Sheet-Sheet-(Helix or Sheet)-Helix-Sheet-(variable)-Helix-Sheet-Sheet. The IIB subfamily consists of Trehalose-6-phosphatase (TIGR00685), plant and cyanobacterial Sucrose-phosphatase and a closely related group of bacterial and archaeal sequences, eukaryotic phosphomannomutase (pfam03332), a large subfamily ("Cof-like hydrolases", TIGR00099) containing many closely related bacterial sequences, a hypothetical equivalog containing the E. coli YedP protein, as well as two small clusters containing OMNI|TC0379 and OMNI|SA2196 whose relationship to the other groups is unclear. [Unknown function, Enzymes of unknown specificity].	7.51884e-15
CP020651.1|AWP83425.1|997894_998281_+|hypothetical-protein	gnl|CDD|281474	pfam03476, MOSC_N, MOSC N-terminal beta barrel domain. This domain is found to the N-terminus of pfam03473. The function of this domain is unknown, however it is predicted to adopt a beta barrel fold.	7.15282e-08
CP020651.1|AWP83434.1|1005822_1006593_-|phosphonates-import-ATP-binding-protein-PhnC	gnl|CDD|213223	cd03256, ABC_PhnC_transporter, ATP-binding cassette domain of the binding protein-dependent phosphonate transport system. Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	6.7095e-115
CP020651.1|AWP83426.1|998288_999506_-|transporter	gnl|CDD|281578	pfam03594, BenE, Benzoate membrane transport protein.	3.72852e-112
CP020651.1|AWP83435.1|1006595_1007603_-|phosphonate-ABC-transporter-substrate-binding-protein	gnl|CDD|270291	cd13573, PBP2_PnhD_3, Substrate binding domain of uncharacterized ABC-type phosphonate-like transporter; contains the type 2 periplasmic binding fold. This subfamily includes putative periplasmic binding component of an ABC transport system similar to alkylphosphonate binding domain PnhD. These domains are found in PnhD-like proteins that are predicted to function as initial receptors in hypophosphite, phosphonate, or phosphate ABC transport in archaea and eubacteria. They belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.92107e-151
CP020651.1|AWP83422.1|994108_994615_-|polyketide-cyclase	gnl|CDD|176905	cd08896, SRPBCC_CalC_Aha1-like_3, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins. SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of a functionally uncharacterized subgroup of CalC- and Aha1-like proteins. This group shows similarity to the SRPBCC domains of Micromonospora echinospora CalC (a protein which confers resistance to enediynes) and human Aha1 (one of several co-chaperones which regulate the dimeric chaperone Hsp90), and belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	7.32648e-83

Protein sequences

>CP020651.1|AWP83431.1|1002280_1003879_-|inorganic-triphosphatase
MSEQELKLHVPAAARAAVQQQIQQRQAARIRLHAMYFDTPGRELARARIAIRLRQEGRDWVQTLKMPGANAISRVEINHPRPGPVLDLSVYAGTEAQAALTAIKGELGLRYETDVQRLFCKVRGRHGTVELAYDTGVLRAGALELPISELEFELVSGRPAAIFAMARSWLQRHGLVLDARSKSERGDALAQLAHDLAAAPGEADDAARATRDQQAVAGFWAPRNAGAVKLDESMTPMQAMAAVAAECVDHIARNAAVLAEVDTLGVYRAGTPEHVHQLRVGVRRLRSAWRLFDGWVADPSETLAQGARTHFSAFGMARDQDVLADTIMPLLARAGMPALPAEAAPSNDNAQSLAADRAFQGWLLELLAWSLDVPPPPAPAATAEAAPASPTIIPLAPPAEAAPPALRKRLTGRLRRWHLKVIDEGLRFGALELEARHELRKRVKRLRYGLSFAESLLPAARLRTYRKQLARVQDLLGEINDLAVARDYYQAALQAHPQAWFAVGWIGARLDGLTPQAQEAFDQLARAKPFWK
>CP020651.1|AWP83430.1|1001028_1002234_+|signal-recognition-particle-docking-protein-FtsY
MPMFSFFKKKSPPPAAPAQPAPPPEAVDAGSAAPAQPQPAEPQPAPMPAPQPEPQPEPQPQQPPEPAPPAMASPPVAEPQPSVAEPQPPVAAAPEAPRKASWLSRLKQGLSRTGQNIGGLFVGVKVDENLFEELESALIMADAGIEATEKLLAALRARVKKERIDDPAQVKTALRQLLADHLRPLERSFDLGRAQPLVVMIAGVNGAGKTTSIGKLAHTFQRQGASVLLAAGDTFRAAAREQLVEWGSRNNVTVISQDGGDPAAVAFDSVNAGRARNVGVVMVDTAGRLPTQLHLMEELKKIRRVIGKAEASAPHEVLLVVDGNTGQNALAQIRAFDAAITLTGLVVTKLDGTAKGGTLAAVAAGSQGVRPIPVYWIGVGEGLEDLQPFVADEFAAALLAD
>CP020651.1|AWP83429.1|1000338_1000959_-|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD
MKPSRPGSKPIRIVGGLYRRTLIPVADAPGLRPTPDRVRETLFNWLNHLWGGEFADKRVLDLFAGSGALGFEAASRGAGQVQMVERDRGAAAALRTLRDKLQAGAVRIHAGDAMQVIERMDASRFDLVLLDPPFGQGWLERLWPLLPAVLAEDGLVYVESETAPAPPAGFELLREGKAGAVHYRLFQFAAMRKSMNNPALEDGASH
>CP020651.1|AWP83428.1|999808_1000318_-|phosphopantetheine-adenylyltransferase
MIIAVYPGTFDPLTRGHEDLVRRAATLFDKVVVGIAHSRNKKPFFTIEERVDIAREVLGHYPNVEVHSFGGLLKDFVRDQNGRVIIRGLRAVSDFEYEFQMAGMNRHLLPDVETMFMTPSDQYQFISGTIVREIAQLGGDVSKFVFPSVERWLQAKAKERREQSAQGGA
>CP020651.1|AWP83427.1|999502_999754_-|ferredoxin
MALKITEECINCDVCEPQCPNEAISMGADYYVIDPDRCTECVGHHDEPQCKVVCPVECIELHPQWQEGQEQLMAKYRRLTGAA
>CP020651.1|AWP83426.1|998288_999506_-|transporter
MNGADSASSPLAARRPVTGALSLSAIVAGLVAVLVSFGGTAVLMVQAGHAAGLDAARIGSWLGSICLALGVGGALISLRSRMPVVFAWSTPGAALLVTGLVGVPFDQAVGAFVLAAALTLACGVFGWIDPIVRRIPAELAAAMLAGVLLNFGMGIFGSIAAQPVLVLSMCAAYLLGRRWAPRFAVLAVLVVGLAAASSLDLLRLGHVQWAWTEFVWTTPSFTWQAAISLGIPLFVVAMASQNLPGLAILQAAGYRPPASRLVGLTGLAGLLAAPFGAHSVTLGAIIAALCAGPEAHADPGRRYVAAATYGLTYVLLSVAAGAVAVFFQALPGALIAALAGLALLGAIMGGMTTAMADPQRREAALVTLLATASGISFWGIGSAFWGLAAGLATHGALAWRRARSA
>CP020651.1|AWP83425.1|997894_998281_+|hypothetical-protein
MSTTAYQPIAECGATTQSEAAAYQKRWLVANDAGQWLNRDLCPRLAEVSVELRMGYLVLKAPGMLRLDIPLDVIEDDDSVRYQMLVGEQTVDVVDEGELAAAWISNHAGVPCRILKVHPDMAEVRWPS
>CP020651.1|AWP83424.1|995378_997898_+|AsmA-family-protein
MKTWFKRIVIGLVVLVVVAVVGLAIFLLTFDPNAYKYKLEEAVQARYERTLNIEGEIELSLFPRIGLAVQGVSLSEPNSPDVFASIDSMRLAVAVWPLLSNSLVVDHVTINGFKARVIRGKDGHFNFENLVGGSVQSTDVPGNAAEATAGAITGTAQAIVNGTVSTPKSMQIDIAGLDLKDGEIQLQDAMSGMAVAITKLNAATGRVTYNQPFDVSLSARVEGGNPRLDAGLTGQAQLTLDPLAKRYAAQRLDLRMEGRLPGAQAKSLAARGNVAFNGMTSSLDVAGLEILFQGDIVDTATKLTNVEASVAMPKLAVDPHKTELQIDKLAVRAKGAMPGGPFELAVDAPALNISPTNASGDALSGRVRTQELDASFGLNGISGNAGELDIKEAKLDSTLKQGERVVKSAFASPVTLNLLQRSIGLSALKGDVNITDPGLPKGSLQIPVIGSVNANLLKDQANARINAVLEGGKFDLSADIVALSAVPRVTFALAVDTLDLDKLAPPAGASAPPKPAGDGKQDESKPPAKPQPAPAPAAADDSINLSGLVGPTASGTIKIGQLVMRGLKAEQVAANIKLEKGKLDISTLTAALYGGKLGGVMSVDAVNGNQLVAKMSLAGIAIQPLLSDLAGKDTLSGTGSLAFDLKTAGANTYAMKSGLAGTMQVRLRDGAIKGINVAQTLRELKAMFRGEAHDPTVQDDQTRQTDFTSLESDLVFNKGVATVKRLDMAAPLLRVNQGNPANIDFVRSELDFVARVRVVNTSTGQDGKDLAELRNLTIPLLITGPFDKPVYTLQWREVAGEALKRGLEKQLKEALTGGEGASGSPAKNIDKALKGILGK
>CP020651.1|AWP83423.1|994611_994950_-|transcriptional-regulator
MPNQAAQLSQVFQALSDPTRRAVLERLCQGSAAMSELARPFNMALPSFSQHLDVLERCGLVRSRKSGRVRIYTLAPQPLGMAEHWMTRQRAIWERRLDQLDLYLQDLKEQKR
>CP020651.1|AWP83422.1|994108_994615_-|polyketide-cyclase
MTRQHSTQPDPKLDLVLERTIDVPPALVWQAWTQPEHIKHWLTPAPWQTVRCDVDLRPGGRFRFVMRSPEGEEHTHDCCYLEIVEGSRLVWTNALLPGFRPAGGGGDVPAFTAVIRIEPHDQGTRYTATAMHGTQAGCRQHSDMGFHDGWGAALDQLVAHARNMQQAS
>CP020651.1|AWP83432.1|1004117_1004939_-|phosphonate-ABC-transporter,-permease-protein-PhnE
MNTSVTSLEPGHPRTWQRYSGGQKALRFMLYLLLVAAIVQAVRSVEVIPEFLYDAPEQMADLLRRMWPIDWSYYPEGVHAALVETLHIATLGTILSVGMAVPVGLLAANNLTPSRTINMLARLILVSSRSVNSLVWALLFIAIFGPGALAGTLAIAFRSIGFVGKLVGEAIEEAQRGPIEALTATGASKAAVLWYGYWPQIRPSFWSIVLLRWDINVRESAVLGLVGAGGIGMALDTALNLFQWDRVALVLAAIFIVVVAAEIVITQARKRIL
>CP020651.1|AWP83433.1|1004935_1005826_-|phosphonate-ABC-transporter,-permease-protein-PhnE
MTVRTANMARRPFSLSWRAKTGVLLVVLYTFYAAAQLDFSWARFETGLGHAATFLARMFPPNFEKPDTLWKGIAESLEIAVLASVLGILLSLPIGLLGARNLMPAWASWPARALVALCRALHPVIVAILFVKAVGFGALAGILALTVASIGFIGKLFTEAIEEISLKQVEAVRASGASFGNVIIFGVLPQVFARFVGFATYQFDSNLRNSTMVGIVGAGGIGGTLFSAFQRFDYDFVAAILLTLIAIIMLGEILAGFVRKVFLDNMGFERILQRRFTAARGLGSTTPLARKGEVDE
>CP020651.1|AWP83434.1|1005822_1006593_-|phosphonates-import-ATP-binding-protein-PhnC
MATSLRITGLVKEYRAGKPVLNGIDLDIAGQGLTAIIGPSGTGKSTLLRCINRLIEPTSGEIVLKDAEGTVDLARVRGQSLRRARRRIGMVFQEYNLVERLTVMENLLTGRLGYTSALNAWMRRFDPADIERAFQLLDTVGLAGFADQRADALSGGQRQRVGIARALMQRPQLLLADEPTSSLDPKTSVEIMELLTEQGSVNGIPVLVNIHDVELARRYANRIVGMSGGHVVYDGDGKGLDATMLKTIYGGESWLE
>CP020651.1|AWP83435.1|1006595_1007603_-|phosphonate-ABC-transporter-substrate-binding-protein
MRAKRLLQAAAVTALIFGSYAAQAADAACSNRGDLDNMYCDANKDLVADTPTDKSKLKTPSTLVFTYTPVEDPAVYEDIFKPFTKHLSECTGKRVVFYQVQSNAAEIEAMRSGRLHVGGFSTGPTAFAVNIAGAVPFAVKGYADEFQGYNLIVIVKKDSPYQKLTDLKGKKLAHTAPSSNSGHMAPVALFPKEGLTPDKDYKVIFSGKHDQSVMGVNSGDYDAAAVASDVFKRMAERGQVKEEDFRVIYRSEKFPTSSFAYAHDLEPAFRDKMLKCFYDYRFPDEMKKAFDGADRFYPVTYQKDWAIVREVAESGGEKFNRAAYDRETAKSKGKQ
>CP020651.1|AWP83436.1|1007751_1008579_-|transcriptional-regulator
MSAAKSTAKPAAAPGNDGRRSIQSVEVGFPLLAALVDAGRPLTLRDLAGAAGMTSAKAHPYLVSFTRVGLVQQDTVTGQYELGPFALQMGLVSLQRLDPVRVALPEVDKLQSEIGHTLGIAVLGSHGPTMIHITEASYPVHVNMRKGTVMSMLHTATGQVFAAWLPPKVAEHYIAREDGDAAVIASLTPRKTTRANLDAMLADIRVHGMARALGNPLPGVDALSVPVFDHTGGIVLALTSLGPTGLFDASFTGAIARPLLACAQEISRKLGYRGN
>CP020651.1|AWP83437.1|1008584_1009382_-|HAD-family-hydrolase
MQALAAMPAPVAASVRIVLTDIDDTLTTEGRLPAGAYAALERLEQAGIVVVPITGRPAGWCDHIARMWPVRAVVGENGAFYYAYDRSARRMNAHYWADAATRAANRQALQAIRERVLREVPGTAVASDQDYRVADLAIDFCEDVPALPDGAVGRIVEIFHEAGAQAKVSSIHVNGWFGDYDKLTMTRTLFEREFGLNIDSALQHTLFIGDSPNDEPMFKFFPISVGVANIQSQLHRIQHRPAFVAAARGGDGFVEMAERLLANRG
>CP020651.1|AWP83438.1|1009527_1010703_+|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II
MSAQISSLNAGAAPESFGIASVPEIIAELRAGRIVILVDEEDRENEGDLVMAAEFVTPEAINFMVTHGRGLVCLTLTEERCRQLDLPLMASRNGTRYGTNFTQSIEAAEGVETGISAADRARTIQVAVARDAQPSDLVQPGHIFPVRAVPGGVLVRAGHTEAGCDLTAMGGLTPAAVICEILKPDGTMARLPDLVEFAREHKLKIGTIADLIQYRSEHESIIARMGERMMQTPWGDFRCIAYRDDATRSPHLALVHGNIDPERETLVRVHEPASLLDVLDTGASPHSWSVGQALHAIAASPAGVLVLMNCQSSTEHLFGQIANWAGPAERAAAQEGDRFGLRTYGIGAQILRDLNVGRMKLLARPRKMPSMAGFALTITGYDCAPPNLRND
>CP020651.1|AWP83439.1|1010716_1011244_+|6,7-dimethyl-8-ribityllumazine-synthase
MNPYILTPDLNGEGLHIGIVRARFNEEIGQAQLQACLEELGKLGVDERDVMVVSVPGALELGVALARMAESYEFDALIALGAVIRGETYHFEVVSNESAAAISRIALETGIPVANGVLTVDTDEQAQARAAGKGADCAQVAVEMANLAAALEPEEDDEDEDDEDEDFDDEEDDGR
>CP020651.1|AWP83440.1|1011251_1011716_+|N-utilization-substance-protein-B
MQARANARSARRRAREFALQGVYAWLLRGGEGTQDAGEIDAHLRDAEDFSEADAQWFKTLLHGVLREAPVLRERFLPYIDRPLAELSPVEHGILLIGSFELMHHVEVPYKVAINEAVELAKSFGGTDGFKFVNGVLDKLAADVRTAEVQAAPRR
>CP020651.1|AWP83441.1|1011755_1012772_+|thiamine-monophosphate-kinase
MLAGVALASEFDLIARYFTRPAPDGVLGVGDDCALFPVPPGQQVATSTDLLIEGRHFFPDVDPQALGHKALAVNLSDLAAMGARPVGCLLGLALPGVDEAWLAAFARGFQALADTHACPLIGGDTTRAPQGLLAISVTVFGAVAPGHALRRAAAQPGDDVWVSGELGAADIAYRLLDRQLPADPLRLAATRAALEWPRPRVELGMALAGLARAGIDISDGLLQDLGHILAASGVAAELRYDALPVAAALAGLPAETVRRAALGGGDVYELCFTADPAHRQAIGQAAHGAGAPVSRIGRILAGQGLRVLDADGAPLGELPGGFDHFSDATDQPAPGRRP

Crispr_ID: CP020651_3

• CRISPR_ID: CP020651_3
• CRISPR_location: 1529896-1529982
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP020651_3

Consensus_repeat	Method
AGTGTGCCTGTCCCCGCAGGGACAG	CRISPRCasFinder

spacers of CP020651_3

>3.1|1529921|37|CP020651|CRISPRCasFinder
ATACCGTCTTGGCGGGCTAGCGTCGATGGCGTACGGC

CRISPR arrays and Neighbor proteins around CP020651_3

CRISPR arrays

The CRISPR arrays of CP020651_3

>merge|CP020651|3|1529896-1529982|CRISPRCasFinder
AGTGTGCCTGTCCCCGCAGGGACAGATACCGTCTTGGCGGGCTAGCGTCGATGGCGTACGGCAGTGTGCCTGTCCCCGCGGGGACAG

>CP020651|3|3|1529896-1529982|CRISPRCasFinder
AGTGTGCCTGTCCCCGCAGGGACAG	ATACCGTCTTGGCGGGCTAGCGTCGATGGCGTACGGC
AGTGTGCCTGTCCCCGCGGGGACAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP020651.1|AWP83890.1|1523321_1524305_-|transaldolase	unknown	unknown	gnl|CDD|235381
CP020651.1|AWP83897.1|1532697_1534407_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224099
CP020651.1|AWP83898.1|1534483_1535806_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270236
CP020651.1|AWP83899.1|1535906_1536224_-|hypothetical-protein	unknown	unknown	unknown
CP020651.1|AWP83887.1|1520639_1521680_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270367
CP020651.1|AWP83891.1|1524567_1525665_+|carbamoyl-phosphate-synthase-small-subunit	unknown	unknown	gnl|CDD|237139
CP020651.1|AWP83900.1|1536357_1537671_+|pyrimidine-utilization-transport-protein-G	unknown	unknown	gnl|CDD|132655
CP020651.1|AWP83888.1|1521672_1522482_+|mannosyltransferase	unknown	unknown	gnl|CDD|224041
CP020651.1|AWP83902.1|1539962_1540439_+|transcription-elongation-factor-GreA	unknown	unknown	gnl|CDD|234693
CP020651.1|AWP83896.1|1531615_1532701_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226361
CP020651.1|AWP83892.1|1525675_1528918_+|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl|CDD|235393
CP020651.1|AWP83893.1|1529068_1529833_+|short-chain-dehydrogenase	unknown	unknown	gnl|CDD|235910
CP020651.1|AWP83889.1|1522485_1523280_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223673
CP020651.1|AWP83885.1|1518600_1519209_+|recombination-protein-RecR	unknown	unknown	gnl|CDD|234616
CP020651.1|AWP83901.1|1537701_1539339_-|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|185001
CP020651.1|AWP83894.1|1530013_1530658_-|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
CP020651.1|AWP83884.1|1518224_1518551_+|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl|CDD|234669
CP020651.1|AWP83903.1|1540793_1541396_-|hypothetical-protein	unknown	unknown	gnl|CDD|198171
CP020651.1|AWP83886.1|1519283_1520534_+|formyl-CoA-transferase	unknown	unknown	gnl|CDD|367110
CP020651.1|AWP83895.1|1530668_1531568_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP020651.1|AWP83890.1|1523321_1524305_-|transaldolase	gnl|CDD|235381	PRK05269, PRK05269, transaldolase B; Provisional.	0
CP020651.1|AWP83897.1|1532697_1534407_-|ABC-transporter-permease	gnl|CDD|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	7.43695e-89
CP020651.1|AWP83898.1|1534483_1535806_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270236	cd13518, PBP2_Fe3_thiamine_like, Substrate binding domain of iron and thiamine transporters-like, a member of the type 2 periplasmic binding fold superfamily. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. On the other hand, thiamin is an essential cofactor in all living systems. Thiamin diphosphate (ThDP)-dependent enzymes play an important role in carbohydrate and branched-chain amino acid metabolism. Most prokaryotes, plants, and fungi can synthesize thiamin, but it is not synthesized in vertebrates. These periplasmic domains have high affinities for their respective substrates and serve as the primary receptor for transport. After binding iron and thiamine with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The iron- and thiamine-binding proteins belong to the PBPI2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.02894e-39
CP020651.1|AWP83887.1|1520639_1521680_+|ABC-transporter-substrate-binding-protein	gnl|CDD|270367	cd13649, PBP2_Cae31940, Substrate binding domain of an uncharacterized protein similar to ABC-type transporter for thiamin biosynthetic pathway intermediates; a member of the type 2 periplasmic binding fold superfamily. This subfamily includes the periplamic-binding protein Cae31940 which is phylogenetically similar to the ThiY/THI5 family. ThiY is the periplasmic N-formyl-4-amino-5-(aminomethyl)-2-methylpyrimidine (FAMP) binding component of the ABC transport system (ThiXYZ). FAMP is imported into cell by the transporter, where it is then incorporated into the thiamin biosynthetic pathway. The closest structural homologs of ThiY are THI5, which is responsible for the synthesis of 4-amino-5-(hydroxymethyl)-2-methylpyrimidine phosphate (HMP-P) in the thiamin biosynthetic pathway of eukaryotes, and periplasmic binding proteins involved in alkanesulfonate/nitrate and bicarbonate transport. After binding the ligand, They interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ThiY/THI5 proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.02712e-131
CP020651.1|AWP83891.1|1524567_1525665_+|carbamoyl-phosphate-synthase-small-subunit	gnl|CDD|237139	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit.	0
CP020651.1|AWP83900.1|1536357_1537671_+|pyrimidine-utilization-transport-protein-G	gnl|CDD|132655	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the uracil-xanthine permease family defined by TIGR00801. As well as the The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40).	0
CP020651.1|AWP83888.1|1521672_1522482_+|mannosyltransferase	gnl|CDD|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	2.56701e-115
CP020651.1|AWP83902.1|1539962_1540439_+|transcription-elongation-factor-GreA	gnl|CDD|234693	PRK00226, greA, transcription elongation factor GreA; Reviewed.	7.10406e-83
CP020651.1|AWP83896.1|1531615_1532701_-|ABC-transporter-ATP-binding-protein	gnl|CDD|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	3.76041e-148
CP020651.1|AWP83892.1|1525675_1528918_+|carbamoyl-phosphate-synthase-large-subunit	gnl|CDD|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
CP020651.1|AWP83893.1|1529068_1529833_+|short-chain-dehydrogenase	gnl|CDD|235910	PRK07024, PRK07024, SDR family oxidoreductase.	4.78988e-141
CP020651.1|AWP83889.1|1522485_1523280_+|ABC-transporter-permease	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	8.9481e-72
CP020651.1|AWP83885.1|1518600_1519209_+|recombination-protein-RecR	gnl|CDD|234616	PRK00076, recR, recombination protein RecR; Reviewed.	7.18255e-106
CP020651.1|AWP83901.1|1537701_1539339_-|methyl-accepting-chemotaxis-protein	gnl|CDD|185001	PRK15041, PRK15041, methyl-accepting chemotaxis protein.	2.87381e-117
CP020651.1|AWP83894.1|1530013_1530658_-|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	5.41773e-70
CP020651.1|AWP83884.1|1518224_1518551_+|YbaB/EbfC-family-nucleoid-associated-protein	gnl|CDD|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	6.20353e-44
CP020651.1|AWP83903.1|1540793_1541396_-|hypothetical-protein	gnl|CDD|198171	smart01103, CRS1_YhbY, Escherichia coli YhbY is associated with pre-50S ribosomal subunits, which implies a function in ribosome assembly. GFP fused to a single-domain CRM protein from maize localises to the nucleolus, suggesting that an analogous activity may have been retained in plants. A CRM domain containing protein in plant chloroplasts has been shown to function in group I and II intron splicing. In vitro experiments with an isolated maize CRM domain have shown it to have RNA binding activity. These and other results suggest that the CRM domain evolved in the context of ribosome function prior to the divergence of Archaea and Bacteria, that this function has been maintained in extant prokaryotes, and that the domain was recruited to serve as an RNA binding module during the evolution of plant genomes. YhbY has a fold similar to that of the C-terminal domain of translation initiation factor 3 (IF3C), which binds to 16S rRNA in the 30S ribosome.	1.06237e-30
CP020651.1|AWP83886.1|1519283_1520534_+|formyl-CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	8.94099e-141
CP020651.1|AWP83895.1|1530668_1531568_-|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	7.08863e-33

Protein sequences

>CP020651.1|AWP83893.1|1529068_1529833_+|short-chain-dehydrogenase
MQHVFITGASSGLGQALARRYAADGARLGLLGRRAQALEALASSLPGQHRCYAVDVRDRAALHAAAQDFIAHCGGRVDVVIASAGVSAGTLTEAGEDYAVFKEIVDTNLLATVATFEPFIAGMRAARAGRLVGIASVAGVRGLPGAGAYSASKAAVATYCESLRLELAQAGVRVVTIAPGYVKTAMTAHNPYAMPFLMEADAFAGRAHAAIARGVSYRVIPWQMGVVAKLMRLLPDAVYDRLARDAPRKPRRGQ
>CP020651.1|AWP83892.1|1525675_1528918_+|carbamoyl-phosphate-synthase-large-subunit
MPKRTDLKSILIIGAGPIIIGQACEFDYSGAQACKALKAEGYRTILVNSNPATIMTDPETADVTYIEPITWQAVEKIIEREKPDALLPTMGGQTALNCALDLAHHGVLKKHNVELIGANEHAIEKAEDRQKFKQAMTDIGLESAKSGVAHSMDEAWEVQRRIAADIGTAGFPVVIRPSFTLGGSGGGIAYNAEEFEVICRRGLEASPTKELLIEESLLGWKEFEMEVVRDKADNCIIVCSIENLDPMGVHTGDSITVAPAQTLTDKEYQIMRNASIAVLREIGVDTGGSNVQFAVNPQNGRMIVIEMNPRVSRSSALASKATGFPIAKVAARLAVGYTLDELRNEITGGATPASFEPTIDYVVTKVPRFAFEKFPQADARLTTQMKSVGEVMAMGRTFQESFQKALRGLEVGVDGLNQKTTDREKLQIELGEPGPERIWYVGDAFAQGFTLDEVHGLTRIDPWFLAQIKEIVDIELALEQKTLADLDYATLWELKRRGFSDRRLAFLLDSSESEVRKLRHQLNVRPVYKRVDTCAAEFATNTAYMYSTYEEECESQPTDRKKIIVLGGGPNRIGQGIEFDYCCVHAALALREDGYETIMVNCNPETVSTDYDTSDRLYFEPLTLEDVLEIVHKENPVGMIVQYGGQTPLKLARALEANGVPIIGTSPESIDVAEDRERFQKLLNKLGLRQPPNRTARTEAEALAHASEIGYPLVVRPSYVLGGRAMEIVHEQQDLERYMREAVKVSNDSPVLLDRFLNDATEVDVDCLADGQTVFIGGVMEHIEQAGVHSGDSACSLPPYSLSAEVIAEIKRQTTMMAKALNVSGLMNVQFAIQGGDVYVLEVNPRASRTVPYVSKATGLQLAKIAARAMAGRTLADQGITREVVPPYFSVKEAVFPFVKFPGVDTILGPEMKSTGEVMGVGNSFGEAFVKSQLAAGVRLPDSGTVFISVRNQDKPRAVEVARGLHNLGFKLVATRGTAAEIEAAGIPVQVVNKVTEGRPHIVDMVKNGEVSLVINTVEERRNAIADSRTIRTQALANRITFFTTIAGARAAVEGMQFMRQGLGLQVYPLQELHAGLTAQ
>CP020651.1|AWP83891.1|1524567_1525665_+|carbamoyl-phosphate-synthase-small-subunit
MADGTIFRGVSIGAPGHTVAEVVFNTSMTGYQEILTDPSYAGQTVMLTYPHIGNTGVNPEDVEANRVYAAGLVVRDCPARVSNFRATQSLPEYLNAQGIVAIAGIDTRKLTRILRESGAQGSCILVGEDAERAVELARGFPGMSGQDLAKVVSIKERADWTQGTWELGSGYTQPAQDRFHVVAYDYGVKSNILRLLADRGCRVTLVPAQTTAEEAFKLQPDGVFLSNGPGDPEPCDYAVDATRAFLERKLPVFGICLGHQLMGLALGGKTVKMKTGHHGANHPVQDVQSGRVFITSQNHGFAVDAATLPANTRVTHISLFDGTLQGFELTDRPAFCFQGHPEASPGPHDIIVLFDKFISLMAGQK
>CP020651.1|AWP83890.1|1523321_1524305_-|transaldolase
MSAQIRLMPSQLEALRRHTVVVADTGDFEAMRALRPTDATTNPSLILKAVQQEAYRPLLVQTARAHQGASPAEITDRLLVAFGRQILDIVPGRVSTEVDARLSFDTRATVERARGLIALYQAAGVPRERVLIKIASTWEGIQAARVLQAEGIRCNLTLLFCLPQAAACADAGVQLISPFVGRIYDWHKKNAGAEWVEDARRGANDPGVQSVSRIYRYYKRFGIETEIMGASFRNVDQILALAGCDLLTISPELLTRLSQTEGEVPAALSPQAGHDDADAVRLDGGEVAFRTQLNEDAMASEKLSEGIRLFVADARKLDALIESHGAA
>CP020651.1|AWP83889.1|1522485_1523280_+|ABC-transporter-permease
MSKLIKPGSLSLRFWQLLLFVVILLVWHAASRDPKVAFFFGEPLKVWGRIWAWFVSNGDIYGHLWVTLSETVLAFFIGTVSGLGFGLWLGLSPGASAILDPYIKAANSMPRVILAPIFGMWFGLGIWSKVALAVTLVFFIVFFNVYQGVREVSPTLLDNARMLGARRRQLLRHVYLPSATSWVFSSLHTSVGLAFVGAVVGEYLGSASGVGYLILQAEGTFDVNTVFAGIVVLTAFALLLDYVVGMGEKRLMKWQPKSGETEKL
>CP020651.1|AWP83888.1|1521672_1522482_+|mannosyltransferase
MAEAALSLEGITCTFIAREDRSRRYTAVQDTSLAVAPGEFVSVVGPTGCGKSTLLNVGAGLLAPSSGTVRVFGQALAGINERAGYMFQGEALLPWRSALENVVAGLDFAGVPRAQADERGREWMRRVGLGGFETRYPHQMSGGMRKRVMLAQTLIRDPDIILMDEPFSALDIQTRQLMENEVLDLWMAKRKAVLFITHDLDEAIAMSDRVIVLSAGPGTHPIGEFAIDLPRPRDVAEVRTHPRFVELHAAIWGVLREEVLKGYAQQKRA
>CP020651.1|AWP83887.1|1520639_1521680_+|ABC-transporter-substrate-binding-protein
MSVTRRELLKLAGAAGAMSLAPAIVRAQKLEKAKVQIAVGGKPLIYYLPLTIAEVKGFFKDEGLDVSIADFAGGSKALQAVVGGSADVVSGAFEHTLSLQAKGQFYRAFALQGRAPMIGVGVSKKNLPGYKGPADLKGRKIGVTAPGSSTNMVVNFFLAKHGLKASDVSFIGVGAGAGAVTALRSGQIDAISNTDPVVSMLETSGDIQIIVDTRTLKDTKEIFGGNMPAGCLYAPQAFVDANPNTAQALTNAIVRADKWIQKAGADEIAKAVPEGYLLGDPAVYKAAIGKSMEGLSPDGVIPEDGAATALKALAAFVPDFDAAKVDPAKAWTNEYTRRANEKYPNG
>CP020651.1|AWP83886.1|1519283_1520534_+|formyl-CoA-transferase
MSALKGLKVLELGTLIAGPFAARMFGEFGAEVIKVETPHGPDGTGGGDPIRSWRHLHRGDSLWWTVQARNKQSIALNLKDPRAQEIARRLALEADVVVENYRPGVLEKWGLGYEQLRAINPATIMVRLSGYGQTGPLRDLPGFGAIGESMGGLRYVSGHPDRPPVRVGISIGDSLAALHGVIGALMALRHRDATGGRWNGATGEQCQAGQGQMVDVALYESVFNMMESLVPEYDVAGVVRERTGGALPGIVPSNTYTTRDGQNIVIAGNGDAIFHRLMLAIGRSDLAHDPQLERNDGRARRATEIDSAIQRWCDTHTIEQALATLRAADVPVGKIYSVADMFTDPQFLARGMIEQHHFPDGSPVKLPAVVPKLSETPGGTRWLGPRLGEHAEEVLRSLGYDAAAIAELAQTGAIGR
>CP020651.1|AWP83885.1|1518600_1519209_+|recombination-protein-RecR
MDPQLPEPEPLIALIEALRRLPGVGVRSARRMAYHLLQHDLQGADMLGRALSGAVQHLRHCARCNSFTEDEVCATCANPKRDPGLLCIVETPADQNMIESSHGYRGLYYVLMGRIAPLEGVGPRELDFQRVIERACDGVVQEVILATNFTAEGETTAHFLGDALSERGLKVTRLARGVPAGSELEYVDAGTIAWALMERRST
>CP020651.1|AWP83884.1|1518224_1518551_+|YbaB/EbfC-family-nucleoid-associated-protein
MMKGQLAGLMRQAQQMQENMKKAQDALAEIQVEGAAGGGLVKVTMTCRHDVKRVAIDPSLLGEDKDMLEDLVAAAFNDALRKAEATSQEKMASVTAGMPLPPGMKLPF
>CP020651.1|AWP83894.1|1530013_1530658_-|histidine-phosphatase-family-protein
MTEIWFIRHGETDWNRQRRLQGWQDIPLNESGREQARLLAERLRDTASEHPFAALYSSDLKRAHDTAASLSAALQLRVRTEPGIRERGFGVLEGLEMENLEQQAPQAAQAWRSRDPLRALESGETLGQFQARIIATVDDLAARHAGERILAVTHGGALDIIWRHASGVPLDAPRYAALLNVSINRVAIAQRKWEVLGWGDVEHIGAETGNDVTP
>CP020651.1|AWP83895.1|1530668_1531568_-|LysR-family-transcriptional-regulator
MEIYQIRAFVTVARLGNLTKAAEALSLTQPAVTAQLKALEQSLGVALFDRAAGRLSLAKAGEALLPTAEALLVLGAQLKSEARQLQGQLQGVIDLGVPSEQPDFLRLGELAAALRQRLPLVELKTHVLPSTALLEQVGTARLAGALTIVAHPPRGVTWHALRSVRYRIALPASLADTLKRAGWRDIAQLPWLDGPSGSHLHLLLRDMFERHGLAPRVVMQNDDQSNLDALVRAGAGCALLREETALAGAAAGDFIVWGQARADATLGFIAPPEQAGEPMLVALISMIQKIWKPGAAVAT
>CP020651.1|AWP83896.1|1531615_1532701_-|ABC-transporter-ATP-binding-protein
MKKVSVECRNIRLSYGRNEVLKDISIHIEPGEFFALLGPSGSGKSTLLRLIAGFNRQSHGQLLVDGRDIGATPPWDRNIGMVFQNYALWPHMTVWDNVAFGLVERRLPRAEIRDKVAAALELVGLADFGRRRPNQLSGGQQQRVALARTIVIEPQVLLLDEPLSNLDKKLRVQMRQDLLSLQRRLGITTIFVTHDQEEAMTTADRMAVLDHGVVQQIGAPSTLFDYPVNRFVANFVGTMNVLEGEVRERSRGGVVLAVDGVGELHLPVNGDAPQAGRLAASFRPHTVLIEMADGTGDARYVWLPGVVESSEFLGEFTRYQVQVGEQRLTADQHHLAGLSPFPVGAPVAVGLEPTQIRLLAA
>CP020651.1|AWP83897.1|1532697_1534407_-|ABC-transporter-permease
MTSTGTFRLPAGPALAALLVLAFLALFLVFPVGTVFYTAFVNADGSFTLGHFGAFFNQPLMKEAFFNSLYVAGWSSLLASLIAVPLAYFTVRFEFRGTLLIQTLGVPPLIMPPFVGAVAMQLIFGRSGSVNLLLDDWLGITLPFMDGLNGVIFVESLHYFPFILMNLVVALRNIDGSMEEAAFNLGSRGFRLFCRIIFPLALPGYLAGTSLVFVKVFDDLGTPLVLGTTNMLAPQAYLRITQVGLEDPLGYVISVIMIGFSILALWLSARVLKGKDYSTLQKGGNAIHKRRLRPVESVLAYAWIGAVLLLVLSPHLGVLLLSLASVWSYAPLPDGYTLAHYTAVFTESQGMIANTLLYCGLAAGVDVVLGTAIAYLMLRTRLPARQWLDFIASAALAIPGIVLAIGYLRTFRGVEIPGTGVLLTSSWVLIMIAYSVRRLPYALRSCVAALQQINVSLEEAAESLGASRLRTIRRIVVPLMAGGMLAGFVTSFITAAVELSATIMLVTRDSQAPMSYGIYLYMQSAAGRGPGAALGVLAVVAVGIGTYVSHLLVERASARQRPARSGESS
>CP020651.1|AWP83898.1|1534483_1535806_-|ABC-transporter-substrate-binding-protein
MQALRPVLAAAIMAACAPALAGTVTVITSFPKDLTQAYKAAFEKAHPDIKLEILNKNTVSGIAFVRETPAGQRPEVFWASAPDAFEVLGRDKLLAKAPDVANPAVPDKIGSYPINDPSGMYMGQALAGYGIIYNTRYIKANKLPAPVEWKDLLAPHWFGHVGITAPSRSGTMHLTVETILQGEGWNDGWGTLLRMSGNASAVTERSFGVPDGVNNGQFGAGPVIDFFGLSSKYSKFPVDFVYPSETAIVPANIALIEGAKNTEEGKKFIAFTLSQAGQELLLEPKISRLPVLPYAALAGKIPPGYPDPAEIAKRSKVHFDADLSQARYYVVQSLFDQTITFRLKELQAATKAIYDAEAKLGERAGQGKAAELLAQARQLAWTPLVDAQRAADPAFLKLFAGNKKDAAVNQQITQLEGEWNGKARANYEQAQKLAREAAAL
>CP020651.1|AWP83899.1|1535906_1536224_-|hypothetical-protein
MTVSSVSSRISAGAFDQYARQLRDRAAASGAKDEAGSPAAEALQALQRRLAAIMRQMRQVRESNATAEQQARQLQDLNRQAFAIQGQIQKLLEEQLRLAQRLAAR
>CP020651.1|AWP83900.1|1536357_1537671_+|pyrimidine-utilization-transport-protein-G
MSNTYFPRWRLADDTVPGAVIAPDERLSWPKNIAMGAQHVVAMFGSTVLAPLLMGFDPNVAILMSGIGTLIFFLFVGGRVPSYLGSSFAFIGGVVAVTGYVAPGANANIGVALGAIIACGLVYALIGLVVWAASARGNGARWIEAMMPPVVTGAVVAVIGLNLAPIAAKGAMGSSGFEASMALMTILCVGGIAVYTRGMVQRLLILVGLVLACVIYAVCANGLGLGAPMDFAKVAAAPWFGLPSFAAPVFEPQAMGLIVPVAIILVAENLGHVKAVAAMTGQDLDRYVGRAFVGDGVATMVSGAVGGTGVTTYAENIGVMAVTRIYSTLVFVVAAVIALVLGFSPKFGALIQTIPGPVLGGMSVVVFGLIAIAGARIWVVNQVDFSDNRNLIVAAVTLVLGAGDFSVKLGDFSMNGIGTATFGAIILYALLGLARRR
>CP020651.1|AWP83901.1|1537701_1539339_-|methyl-accepting-chemotaxis-protein
MPMLERIKVRTAMVAVFACFLAVLMLSGALTWRNAGRSAAEIEGLNQVAVNQVDPLFEASGAALRARVALLEALANLQANHLDPVATLHQQAGAAQRQAATQFQRYVDVPKEPAAAELAATLQTRWRAYQSVLDELAAAVDAGQAEPALAAMNRAQQAEHAFQRDMEAFLARVQAHSDEVRSGAEDTHVVARWSAIALAALGVLLTLAGWLFVRRAVLRPLLEAGHHFDRIADGDLTARIEVRSANAIGALFAALKRMQEGLTRTIAVMRRGVDEINVGAAEISAGNANLSSRTEEQAAALEETAATMEELATTVKQNADNAAQANQLAAVSMQVAQRGGESVAQVVQTMHGISASSRQIADIVTVIDGIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRSLAQRAAQAAKEIKALIESSVATVRAGSQQVASAGGTMDEVVASVQRVADIMGEISAASAQQASGIDQVSLAISQMDETTQQNAALVEQAAAAATAMEEQARHLAAAAAVFRTQGGAIIDIAAAPLAGPAGGHAALPPAAAR
>CP020651.1|AWP83902.1|1539962_1540439_+|transcription-elongation-factor-GreA
MSAIPLTVRGAERLQQELHRLKTVERPAVISAIAEARAQGDLSENAEYDAARERQGFIEGRISELEGTLSNAHLIDPTALDAEGRAVFGATVEIEDLDSGDRLTYQIVGDVEADIKSNLISVSSPVARALIGKSEGDVVEVKVPAGVREYEVIGVRYL
>CP020651.1|AWP83903.1|1540793_1541396_-|hypothetical-protein
MPILELTSRERSDLRSAAHPLRPVVLIGDNGLTDAVLKEIDLALTAHELIKVRAGGDDREAREAMLATICDTLSCAAVHHLGKTLILFRPDLRAAAAKAAADTPAKRRPSEPHTPKKMAAEGKRLTKTRPARKAAEAAAPAAGARPGRDDLNQAGRPARPSTRKASPGHAIPRRSGSALSLRAGARGGLAGRKPARANKR

Crispr_ID: CP020651_5

• CRISPR_ID: CP020651_5
• CRISPR_location: 3124430-3124557
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP020651_5

Consensus_repeat	Method
GCCCCCACGCTGCGCCCGCTACGCGGGCTTGCTGCCCCCCGAG	CRISPRCasFinder

spacers of CP020651_5

>5.1|3124473|42|CP020651|CRISPRCasFinder
AGGGGGCTTTTTTGCCTTGGGGCGGCCCAGCGGCAAAGTAGT

CRISPR arrays and Neighbor proteins around CP020651_5

CRISPR arrays

The CRISPR arrays of CP020651_5

>merge|CP020651|5|3124430-3124557|CRISPRCasFinder
GCCCCCACGCTGCGCCCGCTACGCGGGCTTGCTGCCCCCCGAGAGGGGGCTTTTTTGCCTTGGGGCGGCCCAGCGGCAAAGTAGTGCCCCCACGCTGCGCCCGCTATGCGGGCTTGCTGCCCCCCGAG

>CP020651|5|5|3124430-3124557|CRISPRCasFinder
GCCCCCACGCTGCGCCCGCTACGCGGGCTTGCTGCCCCCCGAG	AGGGGGCTTTTTTGCCTTGGGGCGGCCCAGCGGCAAAGTAGT
GCCCCCACGCTGCGCCCGCTATGCGGGCTTGCTGCCCCCCGAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP020651.1|AWP85273.1|3117616_3118828_-|IscS-subfamily-cysteine-desulfurase	unknown	unknown	gnl|CDD|184450
CP020651.1|AWP85284.1|3130977_3131769_-|3-oxoacyl-ACP-reductase	unknown	unknown	gnl|CDD|235546
CP020651.1|AWP85286.1|3132929_3133361_-|hypothetical-protein	unknown	unknown	gnl|CDD|224462
CP020651.1|AWP85276.1|3120326_3122354_-|UvrABC-system-protein-B	unknown	unknown	gnl|CDD|235395
CP020651.1|AWP85278.1|3123684_3124413_+|repressor-LexA	unknown	unknown	gnl|CDD|234688
CP020651.1|AWP85283.1|3129817_3130981_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173841
CP020651.1|AWP85279.1|3126456_3127419_-|hypothetical-protein	unknown	unknown	gnl|CDD|270296
CP020651.1|AWP85282.1|3128800_3129796_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173838
CP020651.1|AWP85274.1|3118845_3119358_-|Fe-S-cluster-assembly-transcriptional-regulator-IscR	unknown	unknown	gnl|CDD|273927
CP020651.1|AWP85281.1|3128087_3128804_-|3-oxoadipate-CoA-transferase	unknown	unknown	gnl|CDD|131482
CP020651.1|AWP85269.1|3114340_3116203_-|molecular-chaperone-HscA	unknown	unknown	gnl|CDD|235360
CP020651.1|AWP85277.1|3122431_3123634_+|aromatic-amino-acid-aminotransferase	unknown	unknown	gnl|CDD|181731
CP020651.1|AWP85280.1|3127453_3128095_-|succinyl-CoA--3-ketoacid-CoA-transferase	unknown	unknown	gnl|CDD|188219
CP020651.1|AWP85287.1|3133357_3134161_-|enoyl-CoA-hydratase	unknown	unknown	gnl|CDD|223955
CP020651.1|AWP85285.1|3131775_3132933_-|thiolase	unknown	unknown	gnl|CDD|180434
CP020651.1|AWP85272.1|3117172_3117583_-|iron-sulfur-cluster-scaffold-like-protein	unknown	unknown	gnl|CDD|183087
CP020651.1|AWP85270.1|3116332_3116845_-|co-chaperone-protein-HscB	unknown	unknown	gnl|CDD|235133
CP020651.1|AWP85275.1|3119573_3120065_-|protein-tyrosine-phosphatase	unknown	unknown	gnl|CDD|319971
CP020651.1|AWP85271.1|3116847_3117171_-|iron-sulfur-cluster-assembly-protein-IscA	unknown	unknown	gnl|CDD|213674
CP020651.1|AWP85288.1|3134174_3134639_-|oxidoreductase	unknown	unknown	gnl|CDD|239534

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP020651.1|AWP85273.1|3117616_3118828_-|IscS-subfamily-cysteine-desulfurase	gnl|CDD|184450	PRK14012, PRK14012, IscS subfamily cysteine desulfurase.	0
CP020651.1|AWP85284.1|3130977_3131769_-|3-oxoacyl-ACP-reductase	gnl|CDD|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	5.93465e-80
CP020651.1|AWP85286.1|3132929_3133361_-|hypothetical-protein	gnl|CDD|224462	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only].	1.42164e-21
CP020651.1|AWP85276.1|3120326_3122354_-|UvrABC-system-protein-B	gnl|CDD|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP020651.1|AWP85278.1|3123684_3124413_+|repressor-LexA	gnl|CDD|234688	PRK00215, PRK00215, transcriptional repressor LexA.	1.30999e-106
CP020651.1|AWP85283.1|3129817_3130981_-|acyl-CoA-dehydrogenase	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	1.189e-78
CP020651.1|AWP85279.1|3126456_3127419_-|hypothetical-protein	gnl|CDD|270296	cd13578, PBP2_Bug27, Aromatic solutes transporter of Bug (Bordetella uptake gene) protein family; contains the type 2 periplasmic binding fold. Bug27 binds non-carboxylated solute nicotinamide, in contrast to BugD (aspartic acid transporter) and BugE (glutamate transporter) which both bind aliphatic carboxylated ligands. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) receptors present in a number of bacterial species, but mainly in proteobacteria. Bug proteins are the PBP components of the tripartite carboxylate transporters (TTT). Their expansive expansion in proteobacteria indicates a large functional diversity.	2.39297e-140
CP020651.1|AWP85282.1|3128800_3129796_-|acyl-CoA-dehydrogenase	gnl|CDD|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	6.3649e-20
CP020651.1|AWP85274.1|3118845_3119358_-|Fe-S-cluster-assembly-transcriptional-regulator-IscR	gnl|CDD|273927	TIGR02010, Putative_HTH-type_transcriptional_regulator, iron-sulfur cluster assembly transcription factor IscR. This model describes IscR, an iron-sulfur binding transcription factor of the ISC iron-sulfur cluster assembly system. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other, Regulatory functions, DNA interactions].	1.00126e-77
CP020651.1|AWP85281.1|3128087_3128804_-|3-oxoadipate-CoA-transferase	gnl|CDD|131482	TIGR02429, 3-oxoadipate_CoA-transferase_subunit_A, 3-oxoacid CoA-transferase, A subunit. Various members of this family are characterized as the A subunits of succinyl-CoA:3-ketoacid-CoA transferase (EC 2.8.3.5), beta-ketoadipate:succinyl-CoA transferase (EC 2.8.3.6), acetyl-CoA:acetoacetate CoA transferase (EC 2.8.3.8), and butyrate-acetoacetate CoA-transferase (EC 2.8.3.9). This represents a very distinct clade with strong sequence conservation within the larger family defined by pfam01144. The B subunit represents a different clade in pfam01144, described by TIGR02428. The two are found in general as tandem genes and occasionally as a fusion.	1.51824e-141
CP020651.1|AWP85269.1|3114340_3116203_-|molecular-chaperone-HscA	gnl|CDD|235360	PRK05183, hscA, chaperone protein HscA; Provisional.	0
CP020651.1|AWP85277.1|3122431_3123634_+|aromatic-amino-acid-aminotransferase	gnl|CDD|181731	PRK09257, PRK09257, aromatic amino acid transaminase.	0
CP020651.1|AWP85280.1|3127453_3128095_-|succinyl-CoA--3-ketoacid-CoA-transferase	gnl|CDD|188219	TIGR02428, 3-oxoadipate_CoA-transferase_subunit_B, 3-oxoacid CoA-transferase, B subunit. Various members of this family are characterized as the B subunits of succinyl-CoA:3-ketoacid-CoA transferase (EC 2.8.3.5), beta-ketoadipate:succinyl-CoA transferase (EC 2.8.3.6), acetyl-CoA:acetoacetate CoA transferase (EC 2.8.3.8), and butyrate-acetoacetate CoA-transferase (EC 2.8.3.9). This represents a very distinct clade with strong sequence conservation within the larger family defined by pfam01144. The A subunit represents a different clade in pfam01144.	3.32577e-117
CP020651.1|AWP85287.1|3133357_3134161_-|enoyl-CoA-hydratase	gnl|CDD|223955	COG1024, CaiD, Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism].	1.56988e-63
CP020651.1|AWP85285.1|3131775_3132933_-|thiolase	gnl|CDD|180434	PRK06158, PRK06158, thiolase; Provisional.	0
CP020651.1|AWP85272.1|3117172_3117583_-|iron-sulfur-cluster-scaffold-like-protein	gnl|CDD|183087	PRK11325, PRK11325, scaffold protein; Provisional.	5.84746e-99
CP020651.1|AWP85270.1|3116332_3116845_-|co-chaperone-protein-HscB	gnl|CDD|235133	PRK03578, hscB, Fe-S protein assembly co-chaperone HscB.	2.55481e-79
CP020651.1|AWP85275.1|3119573_3120065_-|protein-tyrosine-phosphatase	gnl|CDD|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	1.0991e-75
CP020651.1|AWP85271.1|3116847_3117171_-|iron-sulfur-cluster-assembly-protein-IscA	gnl|CDD|213674	TIGR02011, Protein_yfhF., iron-sulfur cluster assembly protein IscA. This model represents the IscA component of the ISC system for iron-sulfur cluster assembly. The ISC system consists of IscRASU, HscAB and an Isc-specific ferredoxin. IscA previously was believed to act as a scaffold and now is seen as an iron donor protein. This clade is limited to the proteobacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	4.04388e-54
CP020651.1|AWP85288.1|3134174_3134639_-|oxidoreductase	gnl|CDD|239534	cd03450, NodN, NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. Rhizobium and related species form nodules on the roots of their legume hosts, a symbiotic process that requires production of Nod factors, which are signal molecules involved in root hair deformation and meristematic cell division. The nodulation gene products, including NodN, are involved in producing the Nod factors, however the role played by NodN is unclear.	1.35039e-75

Protein sequences

>CP020651.1|AWP85278.1|3123684_3124413_+|repressor-LexA
MRLAFFPWVLQNGAVYPYSPQKRVIAMATKLTERQQEILDLIRQTVARTGFPPTRAEIAQALGFRSPNAAEDHLKALARKGAIELTAGASRGIRLKVPDSATPSAQLTHPLLAQLVLPLVGRVAAGSPILASEHVEREVGVDPGLFAQTPDYLLKVRGMSMRDAGILEGDLLAVKRAAEARNGQIVVARLGDEVTVKRLQRQNGRIELLPENPDFAPIVVANTDEFALEGIAVGLIRTQPLH
>CP020651.1|AWP85277.1|3122431_3123634_+|aromatic-amino-acid-aminotransferase
MSTLFASVELAPRDPILGLNEQYNADTRPGKVNLGVGVYYDDEGRIPLLQAVRKAEVARIEAAAARGYLPIEGIAGYNKGAQALLLGADSPLAAEGRVLTAQALGGTGALKIGADFLRQLLPQSKVLISDPSWENHRALFERAGFPVETYAYYDAATHGLNFEAMLAALQAAPEQTIVVLHACCHNPTGVDPTPQQWEQIAAVVKARNLVPFLDIAYQGFGEGLEQDAAVVRMFAALDLTMFISSSFSKSFSLYGERVGALTVVAGSKDEAARVLSQLKRVIRTNYSNPPTHGGTVVSTVLNTPELFALWENELAGMRDRIRLMRKELVEKIKAQGVAQDFSFVLAQRGMFSYSGLTATQVDRLREEHGIYAVSSGRICVAALNSRNIDAVAAGIAAVLK
>CP020651.1|AWP85276.1|3120326_3122354_-|UvrABC-system-protein-B
MTAPGFVEFPDSPFHLYQPYPPAGDQPGAIDALTEGVSDGLMFQTLLGVTGSGKTYTMANMIARLGRPALVLAPNKTLAAQLYAEMREFFPRNAVEYFVSYYDYYQPEAYVPTRDLFIEKDSSINEHIEQMRLSATKSLLERRDTVIVGTVSCIYGIGNPGDYHAMVLILRTGDRISRREVLARLVAMQYTRNDADFTRGVFRVRGETIDIFPAESPELALRLTLFDDEIESLELFDPLTGRVRQKLPRFTVYPGSHYVTPRETVLRAIETIKEELRERLAQLIADGKLVEAQRLEQRTRFDLEMLQELGFCKGIENYSRHLSGAAPGEPPPTLIDYLPADALMFIDESHVTIGQLGGMYRGDRSRKETLVQYGFRLPSALDNRPLRLEEFEARMRQCVFVSATPAAYEQEHADNVVEQVVRPTGLVDPIVEVRPAHTQVDDLLGEIHKRAALQERVLVTTLTKRMAEDLTDFLSEHGVRVRYLHSDIDTVERVEIIRDLRLGVFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGRAILYADRITDSMRRAIDETERRRAKQIQHNTDHGITARGVSKAVRELIDGVVAPAGHDALESAVPAEVLTDEKAMAREIRRLEKLMMDHARNLEFEQAAAARDALNALKSRLLLDGVG
>CP020651.1|AWP85275.1|3119573_3120065_-|protein-tyrosine-phosphatase
MMTKVLFVCMGNICRSPSAEGVFRHLVNDAGMGDVVRVDSAGTHAFHIGEAPDARAQAAARKRGYDLTHCAARQVTADDFREFDLILAMDWDNLAALQQQCPKAYQHKLMLLMRFANEFEEATVPDPYYGGPEGFGKVLDYLEDACQGVLELVRKRATQYQAA
>CP020651.1|AWP85274.1|3118845_3119358_-|Fe-S-cluster-assembly-transcriptional-regulator-IscR
MRLTTKGRFAVTAMIDLAMRQHSGPVTLAAISQRQNISLSYLEQLFGKLRRHELVDSVRGPGGGYSLARLARNVTVADIIFAVDEPLDATSCGGKRDCTSGNDGKPGKCMTHELWTTLNRKMVDYLDSVSLQDLVDQQRVRQLQEAANQAQGCSAVRVNRSTPVAANATA
>CP020651.1|AWP85273.1|3117616_3118828_-|IscS-subfamily-cysteine-desulfurase
MSNRPIYLDYSATTPVDPRVVEKMIPWLYESFGNPASRSHAFGWEAEDAVEKAREEVAKLVNADPREIVWTSGATESDNLAIKGAANFYAERGKHIITVKTEHKAVLDTCRELERQGFEVTYLDVQDDGLLSLDAFKAALRPDTILVSVMMVNNEIGVIQDIAALGEICREKGIIFHVDAAQATGKVEIDLQKLKVDLMSFSAHKTYGPKGIGALYVRRKPRVRIEAQMHGGGHERGFRSGTLATHQIVGMGEAFRLAREEMGTENERVRMLRDRLLAGLTQIEEVYVNGSMEHRVPHNLNISFNYVEGESLIMAIKELAVSSGSACTSASLEPSYVLRALGRNDELAHSSIRFTLGRFTTEQEIDFTIELIKSRVGKLRDMSPLWEMAQEGIDLNSVQWAAH
>CP020651.1|AWP85272.1|3117172_3117583_-|iron-sulfur-cluster-scaffold-like-protein
MAYSSKVLDHYENPRNVGSFDKGDDSVGTGMVGAPACGDVMKLQIKVNEAGVIEDARFKTYGCGSAIASSSLVTEWVKGKTLDEAMNIRNTQIAEELALPPVKIHCSILAEDAIKAAVQDYKTKHGAETPEAVAAN
>CP020651.1|AWP85271.1|3116847_3117171_-|iron-sulfur-cluster-assembly-protein-IscA
MAVTLTQSAANHVGRYLQKRGKGIGLRLGVRTTGCSGMAYKLEYVDEQAADDVVFDSFGVKVFIDPKSLAYLDGTELDYAREGLNEGFRFSNPNEKATCGCGESFTV
>CP020651.1|AWP85270.1|3116332_3116845_-|co-chaperone-protein-HscB
MAADDHFSLFGLPTRFALDPVQLEQAWRAVAARVHPDRYATASAAERRVAMQWAARANEAYRQLRDPMLRARYLCEQAGVDLQTESNTAMDPAFLMQQMEWREMLDDARRDPAAFAALRAELEQARLRMQQTLSELIDERGDYQQAGTKVREWMFVEKLAQELSAAQPMQ
>CP020651.1|AWP85269.1|3114340_3116203_-|molecular-chaperone-HscA
MALLQISEPGDSPAPHQRKLAVGIDLGTTNSLVAAVRSSVPEVLADAQGQVLLPSAVRYLDGGAVRIGREALLEQARDPLNTIVSVKRFMGRSAADAVASGAPYEFVDAPGMVRLRTVQGDLSPVEVSAQILAVLRQRAEDVLGDDLVGAVITVPAYFDDAQRQATRDAARLAGLNVLRLLNEPTAAAIAYGLDQAAEGIYAVYDLGGGTFDISILRLTQGVFEVIATGGDTALGGDDFDSAIVAHACAGEDVAALPVADRRALLVAARAAREALTDQAQAPFEVTLRDGRAIQATLTRAQFEQLAEPLVGRTLDSARRALRDAGLAVGDVRGVVMVGGATRMPVVRQQVGALFGTEPLTNLDPDQVVALGAALQANLLAGNRAPGEDWLLLDVIPLSLGLETMGGLVERIIPRNSTIPVARAQEFTTFKDGQTAMSVHVVQGERDLVSDCRSLARFELRGIPPMVAGAARIRVTFQVDADGLLSVTAREQSTGVEAAVAVKPSYGLSDDEIARMLADSVTQADSDARARMLREQQVEARQLVESVGAALAADGDLLDPAERATVDQRLQAAAQAQSLDDVEAVRAAVQALSDATEEFAARRMDRSIRAALAGRKLDELA
>CP020651.1|AWP85279.1|3126456_3127419_-|hypothetical-protein
MKTKIKIVTLALCAFSSAVFASSFPSKPINLIVPYPPGGAVDPIARLYAEKISQSWGVPVIVLNRPGAGTTIGLNQAARAEPDGYTVVLGTASITSNAPLYRSLPYDTLKDFTYLSMAGMIPLAITANPRTAVNSMDELVGQLKKKPGSLTYSSSGNGTIIHLGGELFKSLAGVDMVHVPYKGSGPSVMAGVAGEVDLTFDSVFLMDPQVKAGKLKYIAVASEKRLKSLPEVPAIGEKYPGYFVTSWVGFMGPAGIPADITAAWAKEIARVAALPDVSEKLATLGVESVSSTPQQFSAFVESEIRKWEKVVQDAHIPPVQ
>CP020651.1|AWP85280.1|3127453_3128095_-|succinyl-CoA--3-ketoacid-CoA-transferase
MSKGWSNDEIAARIAVDLPEHAIVNLGIGLPILVANHIPEGKTIFFHSENGIIGLGPVPAPGQEDPDIVNAAKKHATLIAGASIVHHADSFSLIRGGRLDYSVLGGLQVSSGGDIANWKVPGQKGGGGVGGAMDLAVGARNVLVMMRHQDKTGASKLVKSCTFPLTAVSAVTRVYTELGIFECAGDAFIVRESAPGIGKDELLRKTEAALTFP
>CP020651.1|AWP85281.1|3128087_3128804_-|3-oxoadipate-CoA-transferase
MTAGTSTHFNQVNGVGMLNKTCESADEAVSVVESGATILISGFGDIGLPFELLHALARTSVKDLTIVSNNAGTGELGLSRLFRNRQVSRLIASFPSQPDSHHYFAAYQEGLVDLELVPQGTLAERIRAAGAGLAGFFTPTGYGTELAQGKECRMFKGKGYVFEEALPGDFAFIKAHVADAYGNLRYRRASRTFNPIMAMAARTTIAEAKQMVPVGSIDPDDVHTPGVFVDRIVEVRDE
>CP020651.1|AWP85282.1|3128800_3129796_-|acyl-CoA-dehydrogenase
MYSDAFEDLLKGRCEPAVVRAIEAGGDVQALWNAIVQSGFLDLMAPEQAGGAAADLADALPLFTALGAYAVPLPVGQAIALRTLLPAGMEVPGGLPSFAPALRTGPDGALRAPRVPYGMLAGPVLGELDGALCLLDARAAQRRDCGLHGEPTADLSWDAGVRQDAVRRLDDAGGAPGRLAAWGAALHAALLTGAMTRCFEMSLQYGNDRTQFGRSIGKFQAVQHQLAVMAEHVAAARIATAAAFRAGLAQPALLPAAIAKARASEAAALAANTAHAVHGAIGVTEEYDLQLYTRRLHGWRLAHGSEAYWHQVVGAALMGSGDGAVQFVRGL
>CP020651.1|AWP85283.1|3129817_3130981_-|acyl-CoA-dehydrogenase
MIVSALIDRFELAELPARAQAFRQDVQAFLKAELPPLPADRRARSWMGFDAGFSRKLAARGWVGVTLPRAYGGAEMDAFSRFVLIEELLCAGAPVSAHWIADRQSGPQIRKFGSEAQRSFYLPRICRGEAFFCIGMSEPNSGSDLASVGTRATRRADGGWTLSGRKIWTTNAQHCHYMIALVRTSGTPQDRNQGLSQFIVDLSLPGVTVRPISDLAGDAHFSEVFFDDVQLSDEALIGQEGSGWEQVTAELAFERSGPERIYSSMVLLDGWIQWLRGRGDVSQTAAVGRYATHLAALRNLSLSVTARLAAGESPVVEAALVKELGTTFEQEIPAAIEAALGSDPGADIDAELLRTCAYVNQVCPTYSLRGGTREILRGMIARGLGLR
>CP020651.1|AWP85284.1|3130977_3131769_-|3-oxoacyl-ACP-reductase
MKETAMQDKLLTLENRQVIVTGAGQGIGRALASAIAELGGRVVAVDLNADALAALREALGHERCVTVAGNVADPSLAQQAVDAGVTAFGGVNGLVNNAGVTRTAMIDKMSISDWQQVIDVHLSGSFYFLQALGRHLLGRAKAGGDGAGAIVNISSDAGRRGTIGQINYGAAKAGVLGLTMCAAREWARYGIRTNTVGFGVVETPMTETIRGEKFRDTYLSQIPLGRWGEADEVVRPVCFLLSDAASYVTGQHLSVNGGYTIGL
>CP020651.1|AWP85285.1|3131775_3132933_-|thiolase
MIQERFPRGKTAIVACATYGIGESPGLSSLDLAVRASVQALDSVDLTPADVDGLFIGLPDDFVSGLSFTEYLGISPRLTDNNRTGGSSFLTHAIHAALALEAGLCDVALIAYGSNQRSGAGKLVSSMRPSPYEGAYKLARPVGAYALAASRYAAQYGLKKEQLGAVALAARQWAQKNPEAYMRAPLTMDEYLASRLVCDPFSVRDCCLVTDGAAAVVMVRADRARDLAARPAYLLGGAAAAWHKDITNMPDLTVTAASLSGPRAMAQAGVTPADIDVLELYDAFTLNTILFLEDLGFCAKGEGGAFVEDGRIAPGGALPVNTNGGGLSCVHPGMYGLFTMVEAAQQLAGAAGERQVAQARLALAHGNGGELSSQATLILGTEETI
>CP020651.1|AWP85286.1|3132929_3133361_-|hypothetical-protein
MTEHPQAASALLPQQEYFAHLADGRFMIQRSRSSGEYVFYPRVAAPRTGAQDLEWVAASGRGTVYATTVMRVRPPAAPYNVCLVELEEGPRMMSRVEGIGPEDVQVGMAVRARIIRDDAGEPLVVFEPAGPSDAGIGQGRAAQ
>CP020651.1|AWP85287.1|3133357_3134161_-|enoyl-CoA-hydratase
MIMSVLEISRVGACAVLTLNRPAARNALDMDLRNALAKALPEIRDDATVRAVVLTGAGGHFCAGGDIRAIAAGQGNADVFEGRNRILSMQRWFDGLVDLEKPVIAAVDGVAFGAGLSLALAADFVLASPRATFCAVFARLGYVPDLGGMYLLPRAVGLARAKALAFSARVVGAPEALEMGIAHQLVDDRPVLDAALELAGRFEQAPAGALGIVKSVMNHAFESDRRTVYMQEALAQALCRESAFHQEAARRFLDKQAPLYQWPQEQQ
>CP020651.1|AWP85288.1|3134174_3134639_-|oxidoreductase
MKKISFDSIAALKAFAGQPAAVGQPIVVDQSAIDTFGDVVHDRQWIHVDPVRAAAESPFGTTIAHGLLTLSLITGWYHQLFEFPGRKLALNYGFDKVRFPAPVPSGSALVGSFRLARVDDLGPDEARCLWEVDVRVAGAERPAMVAEWLMQLRY

Crispr_ID: CP020651_6

• CRISPR_ID: CP020651_6
• CRISPR_location: 3248425-3248540
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP020651_6

Consensus_repeat	Method
TTTTTGCCTTGGGACGGCCCGGCGGCAAAAAAA	CRISPRCasFinder

spacers of CP020651_6

>6.1|3248458|50|CP020651|CRISPRCasFinder
GGCCCCCACGCTGCGCCCGCTGTGCGGGCTTGCTGCCCCCCAAGGGGGCT

CRISPR arrays and Neighbor proteins around CP020651_6

CRISPR arrays

The CRISPR arrays of CP020651_6

>merge|CP020651|6|3248425-3248540|CRISPRCasFinder
TTTTTGCCTTGGGACGGCCCGGCGGCAAAAAAAGGCCCCCACGCTGCGCCCGCTGTGCGGGCTTGCTGCCCCCCAAGGGGGCTTTTTTGCCTTGGGGCGGCCCGGCGGCAAAAAAA

>CP020651|6|6|3248425-3248540|CRISPRCasFinder
TTTTTGCCTTGGGACGGCCCGGCGGCAAAAAAA	GGCCCCCACGCTGCGCCCGCTGTGCGGGCTTGCTGCCCCCCAAGGGGGCT
TTTTTGCCTTGGGGCGGCCCGGCGGCAAAAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP020651.1|AWP85402.1|3255770_3256466_-|hypothetical-protein	unknown	unknown	gnl|CDD|163429
CP020651.1|AWP85390.1|3244536_3245382_-|Flp-pilus-assembly-protein-CpaB	unknown	unknown	gnl|CDD|274472
CP020651.1|AWP85389.1|3243127_3244540_-|secretion-protein	unknown	unknown	gnl|CDD|333965
CP020651.1|AWP85395.1|3248585_3248717_-|entericidin	unknown	unknown	gnl|CDD|227797
CP020651.1|AWP85388.1|3241514_3243131_-|secretion-protein	unknown	unknown	gnl|CDD|227297
CP020651.1|AWP85391.1|3245378_3246035_-|hypothetical-protein	unknown	unknown	gnl|CDD|184854
CP020651.1|AWP85386.1|3239765_3240662_-|hypothetical-protein	unknown	unknown	gnl|CDD|224975
CP020651.1|AWP85392.1|3246031_3246655_-|hypothetical-protein	unknown	unknown	unknown
CP020651.1|AWP85393.1|3246651_3247968_-|hypothetical-protein	unknown	unknown	unknown
CP020651.1|AWP85396.1|3248743_3249439_-|5-carboxymethyl-2-hydroxymuconate-isomerase	unknown	unknown	gnl|CDD|223257
CP020651.1|AWP85398.1|3250187_3251783_-|protoheme-IX-synthesis-protein	unknown	unknown	gnl|CDD|273126
CP020651.1|AWP87277.1|3251786_3252971_-|heme-biosynthesis-operon-protein-HemX	unknown	unknown	gnl|CDD|235899
CP020651.1|AWP85394.1|3247964_3248228_-|hypothetical-protein	unknown	unknown	unknown
CP020651.1|AWP85401.1|3254892_3255612_-|hypothetical-protein	unknown	unknown	gnl|CDD|163429
CP020651.1|AWP85387.1|3240672_3241518_-|pilus-assembly-protein	unknown	unknown	gnl|CDD|227300
CP020651.1|AWP85399.1|3253008_3253833_-|uroporphyrinogen-III-synthase	unknown	unknown	gnl|CDD|119440
CP020651.1|AWP85403.1|3256741_3257623_-|succinyl-CoA-synthetase-subunit-alpha	unknown	unknown	gnl|CDD|180194
CP020651.1|AWP85397.1|3249622_3250159_-|inorganic-pyrophosphatase	unknown	unknown	gnl|CDD|179262
CP020651.1|AWP85400.1|3253829_3254774_-|hydroxymethylbilane-synthase	unknown	unknown	gnl|CDD|234612
CP020651.1|AWP85385.1|3238743_3239544_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP020651.1|AWP85402.1|3255770_3256466_-|hypothetical-protein	gnl|CDD|163429	TIGR03717, R_switched_YjbE, integral membrane protein, YjbE family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family commonly are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains protein YjbE from Bacillus subtilis. A transport function is proposed.	1.70286e-69
CP020651.1|AWP85390.1|3244536_3245382_-|Flp-pilus-assembly-protein-CpaB	gnl|CDD|274472	TIGR03177, pilus_cpaB, Flp pilus assembly protein CpaB. Members of this protein family are the CpaB protein of Flp-type pilus assembly. Similar proteins include the FlgA protein of bacterial flagellum biosynthesis.	3.27424e-49
CP020651.1|AWP85389.1|3243127_3244540_-|secretion-protein	gnl|CDD|333965	pfam00263, Secretin, Bacterial type II and III secretion system protein.	4.23385e-53
CP020651.1|AWP85398.1|3250187_3251783_-|protoheme-IX-synthesis-protein	gnl|CDD|273126	TIGR00540, TPR_hemY_coli, heme biosynthesis-associated TPR protein. Members of this protein family are uncharacterized tetratricopeptide repeat (TPR) proteins invariably found in heme biosynthesis gene clusters. The absence of any invariant residues other than Ala argues against this protein serving as an enzyme per se. The gene symbol hemY assigned in E. coli is unfortunate in that an unrelated protein, protoporphyrinogen oxidase (HemG in E. coli) is designated HemY in Bacillus subtilis. [Unknown function, General].	5.88418e-71
CP020651.1|AWP85388.1|3241514_3243131_-|secretion-protein	gnl|CDD|227297	COG4962, CpaF, Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion].	1.81087e-139
CP020651.1|AWP85391.1|3245378_3246035_-|hypothetical-protein	gnl|CDD|184854	PRK14852, PRK14852, hypothetical protein; Provisional.	0.00208036
CP020651.1|AWP85386.1|3239765_3240662_-|hypothetical-protein	gnl|CDD|224975	COG2064, TadC, Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion].	9.08185e-19
CP020651.1|AWP85396.1|3248743_3249439_-|5-carboxymethyl-2-hydroxymuconate-isomerase	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	9.66779e-90
CP020651.1|AWP87277.1|3251786_3252971_-|heme-biosynthesis-operon-protein-HemX	gnl|CDD|235899	PRK06975, PRK06975, bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed.	4.52015e-54
CP020651.1|AWP85395.1|3248585_3248717_-|entericidin	gnl|CDD|227797	COG5510, COG5510, Predicted small secreted protein [Function unknown].	8.70055e-07
CP020651.1|AWP85403.1|3256741_3257623_-|succinyl-CoA-synthetase-subunit-alpha	gnl|CDD|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
CP020651.1|AWP85387.1|3240672_3241518_-|pilus-assembly-protein	gnl|CDD|227300	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion].	3.18806e-34
CP020651.1|AWP85399.1|3253008_3253833_-|uroporphyrinogen-III-synthase	gnl|CDD|119440	cd06578, HemD, Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in the human uroporphyrinogen-III synthase gene cause congenital erythropoietic porphyria, a recessive inborn error of metabolism also known as Gunther disease.	4.88788e-45
CP020651.1|AWP85397.1|3249622_3250159_-|inorganic-pyrophosphatase	gnl|CDD|179262	PRK01250, PRK01250, inorganic diphosphatase.	2.68623e-113
CP020651.1|AWP85400.1|3253829_3254774_-|hydroxymethylbilane-synthase	gnl|CDD|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	8.72133e-165
CP020651.1|AWP85401.1|3254892_3255612_-|hypothetical-protein	gnl|CDD|163429	TIGR03717, R_switched_YjbE, integral membrane protein, YjbE family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family commonly are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains protein YjbE from Bacillus subtilis. A transport function is proposed.	3.14656e-77

Protein sequences

>CP020651.1|AWP85394.1|3247964_3248228_-|hypothetical-protein
MSVKQRQLGQGMTEYIIVVALVAVAAIAVYQLFGQVVRSQTAAMARELAGEDGSAQARAAQSAAGRAASQTRARSLKSFTGNAQGAK
>CP020651.1|AWP85393.1|3246651_3247968_-|hypothetical-protein
MRPTRAAVTRQAGQALALGLALMALAGMAWLALYGLGQRAGARAQLLRATDAAAYSGAVVQARALNLLAYIHRAQVGHQVALAHLASLAAWARFAQTQAARRTAQNPPVALIGLLFGPRAARGYGAAHDALAGDLMQAYAAHDELAHRVLQQAADTLARDARATRDATMRAVLRAHYPQGDDGLTLEVLRDDWPGYLRRVPGTSARGLRGWAQRAAGYFDFLQPRDFTREGNWIVSPRCPTRRHELRRRGVTWLDRDGRWGASDTLSFHAVRSNRWIGCYFREYAMGWGLAADSGATRAGPHVLRAPEDFSQQDFWRWVHRHTSWSLLGGRHNPLALSYAASRRLSPGGRGLPAVYEPASSSEAAVGFEIRTQRREEGIVLSARAAGQSHFSLPPGTSVARGRPDVLFLPYWQARRAAADAALPMAARRTVRGPESRP
>CP020651.1|AWP85392.1|3246031_3246655_-|hypothetical-protein
MRGAAFSRRQRGQALAEALPLLAMLLLAWAAVAWLGTLRHQALRLGQHSRVAAFMAAAAAPSAPRTATLARQAGLAGRTAADGMPALLARDWLQVDTRLLHAQAAEPAAMPGGLLREGAIAAALRGVTVLAIGPGHASDARAGNDRLARSVAGWQLAHRAAAPAVAATRRRVRPVEAAWGLRDAGQDWLRTWADMASADGAVLRRQP
>CP020651.1|AWP85391.1|3245378_3246035_-|hypothetical-protein
MTPAHLAASASAWLHLPPGVVAAALAGQIQMFGVPAEVRVFHAPQGIDALLAHFATRHAELRDLTVLPGLAVLAGGAGDCTHTISLAPQSGGVEGVAARLCWPRGLPSRQPLADVLLPPHARLRLDVATRDGPVSVAQQVWHWRAAGPTETARWAVRREARLRASGWRLQGAAGPACRCGAPQTWLRAGPQGRERLSLQPALHANGCGMRLLHIGGAP
>CP020651.1|AWP85390.1|3244536_3245382_-|Flp-pilus-assembly-protein-CpaB
MRAARWRQGLRALGGYAFALVAGSLAAWAAREHIQRRVHDIEQQARVPMVASLVAARDLEAGTPLHDELVAVRDMPQAWLPAGALLPDEAARLDGAVLRAPVKAGEALQAALLSYPEQTPALTEQLEAGQGAITLPLQELPGLSAAARPGDLVDLYVSFTHRQRQLTMPLLAGSKVLALDPADAQGGASTITLRASAREVARLVAARQEGTLTAVLRRAGAPAQGPARAFAAPSAREAGDLPALLGMPRDAAPRAAVPVLYGDRLDAPAGALPGDTEAVMP
>CP020651.1|AWP85389.1|3243127_3244540_-|secretion-protein
MSMRSRLPLHARGWLPWMAVLLAGGSMLWTPGGRAASPAQPAVLRMEVGETQVLAAAGVTRVAVGNGQVLSATVVDGAEVALFARQPGTSSVHIWSGRGARQAYAVEVLPAGRRRLREEVAALLARIPRARSSAVGAHIVIEGSQLSEDDHARIATLAQRYPEVLDFTGRVGWDRMVLLDVQVVELPRQSLRELGLRWDEPAAGGVHAGAVWNGGSAALAPPPGPLAGAAAVRHAGGLLGVNALLSARLSALAQRGEAVLLAQPQLLARSGATASFQAGGELPYRATDKEGNGTTLFKPYGVSLQITPRIDADGAVHARIEVEASSVDPTLALAAGPALRKRRAVTEFNVHSGQTLVLGGFLSRERSHEEKGLPWLSELPLIGALFGARRAALRETELAIFVTPTIVSPSDSFLQRRALLGQMQLDQAFPEAPRLGTGAAADQSADWSRPGGAGSQWRQPPSADAQEGAP
>CP020651.1|AWP85388.1|3241514_3243131_-|secretion-protein
MNVLELALHFEDGARRRMRLAAPVTIGRGAQCALRIANWRVGRVHARLSCLDGAVVLEDLGTLGGTSVNGLRVATHAPVLPDDEIVIGPCLIRVSACCTGSAPSPAPAALPAGGASRGEDLDAALQQSLVLLPHRRRLHAALLEALDLRRRDVSAMSDRMLRAQAEQRLVELVGQDGELPEGIDRAQLCRAVLDEAVGLGPLEPLLADGGISEIMVNRHDEIYVERAGRLQRHAAAFSSEQAVRWVVERIVAPLGRRIDDSSPMVDARLPDGSRVNAVIAPIAIRGVSLTIRKFPRQRPGMADLLAAGSLSEPMARFLLQCVHARKNLLVSGGTGSGKTTLLNILSNAIPEGERIVTIEDAAELRLDHAHLVALEARPANAEGRGRVDIRDLVRNALRMRPDRIVVGECRGAEAFDMLTAMNTGHEGSLTTLHANTPRDALARLEAMTLMAGLDLPLPVVREHIAASIDIIVQQARMADGRRIVTAIVEIAGMESGRIQTQELFRYDARHGFIAGDAPVLADGAWARGPFTGQPEPAP
>CP020651.1|AWP85387.1|3240672_3241518_-|pilus-assembly-protein
MIWLAMGMAMAAAAWLAWRVLAWSGPAARRYRAVYTQQAGAHLSEVFLFVDPAQLWAAALAMAAAGAAAAWVFSGSAWLAAVAAVALLRLPHLLLGAARRRRLRQLERQLPGALVAMACALRAGAGIAAALRQLVEHGEAPLAQEFGLLLREQRMGVSFDAALARLARRASFESMALVAAALRVAAHTGGNLAETLEGIAQTVSARLQLQDRVRALCAQGRMQAWIVGALPPVLMGVLGRLQPEAMAALWHTLYGWAALALIVVLEGTGIWLIRRIVAIDV
>CP020651.1|AWP85386.1|3239765_3240662_-|hypothetical-protein
MWLWLAASVAGVAAGWACLALLRGWCGAGWAAACGPEPAPGPPAWRLPRIWRCCRPWLGPLLPWCDRLLSWRMRAVIERAIVRAGCDGLVRPCEVAALSLWMAWLGGVVAVTAASLADGWRAWLPLAPAACAAGAWPALWLRRCAARRRQRIARELPFILDLMTLCAEAGLGMHGALQQAASHGPPGPLRELLVQALCDMRAGMPRRQAMQALAARADSPPVRAWVGALAHADAQGMSLGPMLRGLATRYRAERHQRAERLAMEAPVKMLLPLIACIFPCTFIVLAFPIGYALLQGGL
>CP020651.1|AWP85385.1|3238743_3239544_+|hypothetical-protein
MQAVSLPAISGWQWVRDGLRLFMKQPLAMFTWAMAISLLLLFATYTPLVGPLLFVALMPSITLMTLSACKHVEAGRVMLPSMWLQPLKKPGVFKKLFLMGMLYVGLCLAAGLLAFLPFSSSLAEGVRMASANNLAPIMTAMRAPLLVFTALYVIIAAVFWHAPVLVGWHGLRLLQALFFSGIACWRNKWPFLVYGVVWILVFLFIDLCIGLLIGMGVPDTLAGTLQVPVTIIAGGVLYCSFYPAYTSVFGVNDAHAGLDNSDSAHA
>CP020651.1|AWP85395.1|3248585_3248717_-|entericidin
MRSKIVLTAFVVFGFVLQGCNTVAGMGKDMSDAGSAITHAAEK
>CP020651.1|AWP85396.1|3248743_3249439_-|5-carboxymethyl-2-hydroxymuconate-isomerase
MDYVFPPSPPAAVPVAGGNARFPVRRVYCVGRNYAEHAKEMGFTGREDPFFFCKPADAILSVADGATGEMPYPPKTANLHYEMELVVVLGKGGRDLTVEQADECVWGYALGLDMTRRDLQGEAKKQGRPWEVGKAFDLSAPLGPIHPRSAVGTLDKGAIWLDVNGERKQSSDISQMIWNIPESVAYLSGLFELQPGDIIFTGTPEGVGAVVKGDVIVGGVEGLGELRVRIA
>CP020651.1|AWP85397.1|3249622_3250159_-|inorganic-pyrophosphatase
MSLDRVAPGKKLPDDFNVIIEIPMNADPVKYEVDKESGAIFVDRFMLTAMHYPCNYGYIPQTLSEDGDPADVLVLTPFPIQIGAVVRCRAIGVLEMDDESGGDAKLLAVPIEKLYPPYRNIKSYEDLPAEDVSRIQHFFEHYKDLEKGKWVKVKGWKGVDAAHEEIVRSAERYAKGQA
>CP020651.1|AWP85398.1|3250187_3251783_-|protoheme-IX-synthesis-protein
MRTWFWTLLLAVVAVALAVVLRAHAGNVLLLVWPWRIELSLTLTVLLLVAAFVTLYIGLRLLAWLVAIPDRLRAWRGRRAQERDHELLERGWIGLLEGRFAQAEKDLSKLFDQTKVRSRRVLAALSGARAAHNLGEYERRDRMLESAREQAGEDAGLQEATATVSADMLLDQGRAQQALDLLEPLQDGGARHLHTMRLLLRAETALQHHERVFMLARGLLRRNAIGKAEAEQLIDSAGAARLRAGMAVDQWRPIWKDLKSDERLLPNIALAGAAAFEDAGEASEAARILEAAVAVKFNPALVAAYARCDAAQVPHRLAKAETWLQQRPADTDLLTALGLLCLNGQLWGQAERYLQRSVSRRNDPQAHALLGSLYDRLDRPADAARHWRQATAARVALPVLAADIALPAADTKADPAWLDAEREYVPNMSEYTAPVIADAPPEVEPGAVDYVLDPDARAAGEHEPASAVAPEPVSVPPRTAIDIEDYFDSAPIPAAAIEAPVSSYRAGGDDEQPAKPGGAVSSAGPASGDKA
>CP020651.1|AWP87277.1|3251786_3252971_-|heme-biosynthesis-operon-protein-HemX
MTDNTSATPPGTVPGTPGTAAADEAVASQSRKGKGVNSTLVTALIIVILLAVGLGWAAWLQRKQFVSAGQEVAARLNTLGAELTQSRNDMREALALAQAQSGKVAELEGKVREAQSQYSALQQALQNLNDGASDEMLANDIERLITIASQQLRLAGNVSNAIVALETAQARLARADRPRFASLQQSINGDLDRLRAVGVVDIAAQSARIDRLVALVGRAPLLVPDAAAPGVTAVPQANEAVPASVDPGADLPADAAWWQRWQAEIASWPGRAGSALAHELGDLIRVQRVDQPTALLLSPEQAGQLRSTLRQRLLTAQLSMLMRQPAVWKSELDAVAATLAQYFDGKAPDTVAALALARELGQVEIAVRVPDVADSLNGIAALRAAGFNADGQQD
>CP020651.1|AWP85399.1|3253008_3253833_-|uroporphyrinogen-III-synthase
MTGRSGPRGGLPMSQIAILTRPQGRNGALAQRLHEAGWQTLCLPALRIEPLPPENGAVPLPRDYDLVVFVSGNAARLYLEQLGERGQLPWPAGAVAATVGPASARALLDSGQFGADTTVLHPAETAPTHDSEALWSLLRARPALPRRALLVRGTQGRDWLADRLAAAGVEVSRHAVYRRRPAPWAQEGRQRLRDWARAGERPTWLLTSGEGIDALVQGLREEQLLDWWLQGRFVVTHPVLAERLRALAGGGADAPMVKNCMPADEAIFATFVAA
>CP020651.1|AWP85400.1|3253829_3254774_-|hydroxymethylbilane-synthase
MAAVERLTIATRASRLALWQAEHVRDLLRARYPACSVELLTLTTRGDQILDRTLSKVGGKGLFVKELETALLDGRADLAVHSLKDVPVDLHAPFELSCVLERADPRDAFVSNDYGSLADLPPGAAVGTSSLRRESQIRARYPHLVVKPLRGNLDTRLGKLDNGDYAAIVLAAAGLERLGLAARIRALLEPADSLPAAGQGALGIEILQGRADVRAMLAPLGDAATLACVTAERAVSRMLGGSCQVPLAAYARIDGDELALRALVAAPDGRRIVRAERRGPRDQAQAIGESAARDLLADGADAILAELLPTSPAP
>CP020651.1|AWP85401.1|3254892_3255612_-|hypothetical-protein
MLEFFQTLSWAAVFQIILIDILLGGDNAVVIALACRNLAPKQRMQGILWGTAGAIILRVVLIAFALTLLNIPFLKVVGGLLLVWIGVKLLVPEDEGHDSIKGGTSIVAAVKTIIIADFVMSLDNVIAIAGAAQNAHADHQIGLVVFGLVVSVPIIIWGSTLVLKLIDRFPMVVTFGAALLGWIAGGMLITDVFVVRQFGEQPSAVKIGVEIAGALLVVLLGRWLASRKTASKESVNESA
>CP020651.1|AWP85402.1|3255770_3256466_-|hypothetical-protein
MELSSAAFWIALLQIIWVNILLSGDNAVVIALAARSLPPDQQKKAIVVGSAAAIVMRIVLTLVAAKLLLLPWLKLIGAALLVYIGVSLLLPEGEDDGAEKGHGSLLVAIRTIMIADLVMSLDNVVAVAAAAMGDTTLLVLGLAISIPLVIFGSALLLKVIERFPIIVWVGAALLGFIAGELLVGDPALEESVARIDTMLGVTQHDFALMVGAIGAILVLALGKIFQARQRA
>CP020651.1|AWP85403.1|3256741_3257623_-|succinyl-CoA-synthetase-subunit-alpha
MSILINKDTKVITQGITGKTGQFHTRMCREYANGKAAFVAGVNPKKAGEDFEGVPIYANVKDAKADTGATVSVIYVPPAGAAAAIWEAVEAELDLVICITEGIPVRDMLEVKNRMQAMNSKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGIVSRSGTLTYEAVAQVTELGLGQSSAVGIGGDPINGLKHVDVLKLFNDDPDTDAVIMIGEIGGPDEVNAAQWAKDNMKKPVVGFIAGVTAPAGKRMGHAGALISGGADTADAKLEVMEACGIRTTRNPSEMGKLLKSVL

Crispr_ID: CP020651_7

• CRISPR_ID: CP020651_7
• CRISPR_location: 4108734-4108859
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP020651_7

Consensus_repeat	Method
GGGGGGCAGCAAGCTGGCGCAGCGAGCGCAGCGTGGGGGCATTTTC	CRISPRCasFinder

spacers of CP020651_7

>7.1|4108780|34|CP020651|CRISPRCasFinder
CACCGCCGGGCCGCCCCAAGGCAAAAGCCCCCCT

CRISPR arrays and Neighbor proteins around CP020651_7

CRISPR arrays

The CRISPR arrays of CP020651_7

>merge|CP020651|7|4108734-4108859|CRISPRCasFinder
GGGGGGCAGCAAGCTGGCGCAGCGAGCGCAGCGTGGGGGCATTTTCCACCGCCGGGCCGCCCCAAGGCAAAAGCCCCCCTGGGGGGCAGCAAGCTGGCGCAGCGAGCGCAGCGTGGGGGCTTTTCT

>CP020651|7|7|4108734-4108859|CRISPRCasFinder
GGGGGGCAGCAAGCTGGCGCAGCGAGCGCAGCGTGGGGGCATTTTC	CACCGCCGGGCCGCCCCAAGGCAAAAGCCCCCCT
GGGGGGCAGCAAGCTGGCGCAGCGAGCGCAGCGTGGGGGCTTTTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP020651.1|AWP86156.1|4108863_4109193_-|hypothetical-protein	unknown	unknown	gnl|CDD|226827
CP020651.1|AWP86162.1|4112965_4114483_-|peptidase	unknown	unknown	gnl|CDD|227122
CP020651.1|AWP86159.1|4111094_4111307_+|zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|226826
CP020651.1|AWP86151.1|4104011_4104860_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
CP020651.1|AWP86149.1|4098345_4099323_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270294
CP020651.1|AWP86165.1|4116382_4117477_-|porin	unknown	unknown	gnl|CDD|238208
CP020651.1|AWP86158.1|4110127_4111048_+|branched-chain-amino-acid-aminotransferase	unknown	unknown	gnl|CDD|235841
CP020651.1|AWP86148.1|4097380_4097959_-|Phasin-(PHA-granule-associated-protein)	unknown	unknown	gnl|CDD|130900
CP020651.1|AWP86152.1|4105018_4105831_-|competence/damage-inducible-protein-A	unknown	unknown	gnl|CDD|223986
CP020651.1|AWP86160.1|4111329_4111752_+|DUF4440-domain-containing-protein	unknown	unknown	gnl|CDD|379209
CP020651.1|AWP86161.1|4111768_4112869_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223506
CP020651.1|AWP86164.1|4115419_4116301_-|hypothetical-protein	unknown	unknown	gnl|CDD|378238
CP020651.1|AWP86147.1|4096183_4097233_+|dihydroorotate-dehydrogenase-(quinone)	unknown	unknown	gnl|CDD|235388
CP020651.1|AWP86163.1|4114558_4115398_+|UTP--glucose-1-phosphate-uridylyltransferase	unknown	unknown	gnl|CDD|224131
CP020651.1|AWP86155.1|4107142_4108576_-|ATP-dependent-RNA-helicase	unknown	unknown	gnl|CDD|223587
CP020651.1|AWP86150.1|4099416_4103811_-|dermonecrotic-toxin	unknown	unknown	gnl|CDD|283449
CP020651.1|AWP86153.1|4105885_4106686_-|hypothetical-protein	unknown	unknown	gnl|CDD|377798
CP020651.1|AWP86146.1|4095408_4096143_+|arginyltransferase	unknown	unknown	gnl|CDD|234939
CP020651.1|AWP86154.1|4106747_4107131_+|thiol-reductase-thioredoxin	unknown	unknown	gnl|CDD|239245
CP020651.1|AWP86157.1|4109195_4109864_-|hypothetical-protein	unknown	unknown	gnl|CDD|224215

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP020651.1|AWP86156.1|4108863_4109193_-|hypothetical-protein	gnl|CDD|226827	COG4392, COG4392, Predicted membrane protein [Function unknown].	7.8037e-15
CP020651.1|AWP86162.1|4112965_4114483_-|peptidase	gnl|CDD|227122	COG4783, COG4783, Putative Zn-dependent protease, contains TPR repeats [General function prediction only].	4.64199e-95
CP020651.1|AWP86159.1|4111094_4111307_+|zinc-finger-domain-containing-protein	gnl|CDD|226826	COG4391, COG4391, Uncharacterized protein conserved in bacteria [Function unknown].	5.98518e-12
CP020651.1|AWP86151.1|4104011_4104860_-|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	4.34506e-72
CP020651.1|AWP86149.1|4098345_4099323_+|ABC-transporter-substrate-binding-protein	gnl|CDD|270294	cd13576, PBP2_BugD_Asp, Aspartic acid transporter of Bug (Bordetella uptake gene) protein family; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) receptors present in a number of bacterial species, but mainly in proteobacteria. Bug proteins are the PBP components of the tripartite carboxylate transporters (TTT). Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	5.90091e-161
CP020651.1|AWP86165.1|4116382_4117477_-|porin	gnl|CDD|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	8.91426e-53
CP020651.1|AWP86158.1|4110127_4111048_+|branched-chain-amino-acid-aminotransferase	gnl|CDD|235841	PRK06606, PRK06606, branched-chain amino acid transaminase.	0
CP020651.1|AWP86148.1|4097380_4097959_-|Phasin-(PHA-granule-associated-protein)	gnl|CDD|130900	TIGR01841, hypothetical_protein, phasin family protein. This model describes a family of small proteins found associated with inclusions in bacterial cells. Most associate with polyhydroxyalkanoate (PHA) inclusions, the most common of which consist of polyhydroxybutyrate (PHB). These are designated granule-associate proteins or phasins; the member from Rhodospirillum rubrum is an activator of polyhydroxybutyrate (PHB) degradation. However, the member from Magnetospirillum sp. AMB-1 is called a magnetic particle membrane-specific GTPase.	3.19978e-10
CP020651.1|AWP86152.1|4105018_4105831_-|competence/damage-inducible-protein-A	gnl|CDD|223986	COG1058, CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only].	2.67138e-63
CP020651.1|AWP86160.1|4111329_4111752_+|DUF4440-domain-containing-protein	gnl|CDD|379209	pfam13474, SnoaL_3, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.07341e-14
CP020651.1|AWP86161.1|4111768_4112869_+|alpha/beta-hydrolase	gnl|CDD|223506	COG0429, COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only].	1.04959e-90
CP020651.1|AWP86164.1|4115419_4116301_-|hypothetical-protein	gnl|CDD|378238	pfam09678, Caa3_CtaG, Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG). Members of this family are the CtaG protein required for assembly of active cytochrome c oxidase of the caa3 type, as found in Bacillus subtilis.	4.8617e-46
CP020651.1|AWP86147.1|4096183_4097233_+|dihydroorotate-dehydrogenase-(quinone)	gnl|CDD|235388	PRK05286, PRK05286, quinone-dependent dihydroorotate dehydrogenase.	0
CP020651.1|AWP86163.1|4114558_4115398_+|UTP--glucose-1-phosphate-uridylyltransferase	gnl|CDD|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	2.75704e-156
CP020651.1|AWP86155.1|4107142_4108576_-|ATP-dependent-RNA-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	8.74039e-162
CP020651.1|AWP86150.1|4099416_4103811_-|dermonecrotic-toxin	gnl|CDD|283449	pfam05785, CNF1, Rho-activating domain of cytotoxic necrotizing factor. This family consists of several bacterial cytotoxic necrotizing factor proteins as well as related dermonecrotic toxin (DNT) from Bordetella species. Cytotoxic necrotizing factor 1 (CNF1) causes necrosis of rabbit skin and re-organisation of the actin cytoskeleton in cultured cells. Bordetella dermonecrotic toxin (DNT) stimulates the assembly of actin stress fibers and focal adhesions by deamidating or polyaminating Gln63 of the small GTPase Rho. DNT is an A-B toxin which is composed of an N-terminal receptor-binding (B) domain and a C-terminal enzymatically active (A) domain.	7.27553e-144
CP020651.1|AWP86153.1|4105885_4106686_-|hypothetical-protein	gnl|CDD|377798	pfam07264, EI24, Etoposide-induced protein 2.4 (EI24). This family contains a number of eukaryotic etoposide-induced 2.4 (EI24) proteins approximately 350 residues long as well as bacterial CysZ proteins (formerly known as DUF540). In cells treated with the cytotoxic drug etoposide, EI24 is induced by p53. It has been suggested to play an important role in negative cell growth control.	1.28978e-07
CP020651.1|AWP86146.1|4095408_4096143_+|arginyltransferase	gnl|CDD|234939	PRK01305, PRK01305, arginyl-tRNA-protein transferase; Provisional.	6.93678e-140
CP020651.1|AWP86154.1|4106747_4107131_+|thiol-reductase-thioredoxin	gnl|CDD|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	1.97539e-15
CP020651.1|AWP86157.1|4109195_4109864_-|hypothetical-protein	gnl|CDD|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	2.16802e-27

Protein sequences

>CP020651.1|AWP86155.1|4107142_4108576_-|ATP-dependent-RNA-helicase
MTESTSSDAPVTDAPTRTFADFGLHPLLLKSIADTGYTNPTPIQAQAIPVVVEGRDVMGAAQTGTGKTAAFTLPILHRLMPLANTSASPARHPVRALILTPTRELADQVYESVKRYSLHTPLRSAVVFGGVDIGPQKEALRRGCEVLVATPGRLLDHVEQKNVNLSQVGILVLDEADRMLDMGFLPDLERIIRLLPAQRQGLLFSATFSNEIRKLGRSYLNHPVEIEVAARNATADTVTQIAYQMHGDTKRAAVVHLVKSRGLKQVIVFSNTKIGTARLARQLERDGVKAESIHGDKTQGDRMKALEAFKAGDLEVLVATDVAARGLDVAGVPCVINYDLPYNAEDYVHRIGRTGRAGASGEAIALFTADEERYLLDIEKLIKRQVPRGKLELPADLVARSHGRDRDAPRERGADRHRGERRTSGAAAPRQPVDELFYKPYEPANGQPASPETPKQEGRSNAPKRQLAVLLGGSRKG
>CP020651.1|AWP86154.1|4106747_4107131_+|thiol-reductase-thioredoxin
MPLHVPGSDIPTLRAALARSDAWLVACFCAAWCDTCQQYRPKLLELARARPGHTFAWIDIEDHPDLLGEEDVENFPTLLVQAHGKVLFYGPMLPHIGHLERLLDSLDPQGRPVATGLPDVARLLAAA
>CP020651.1|AWP86153.1|4105885_4106686_-|hypothetical-protein
MTVPRPESIIPPAGNAATGAAGIARAFKRALVSQCHPNMLFAVLLPFLIALLGAILLLWLFWTPLNEWLRFEASQWQAINQVDDWMVAAGLFSLKIYLVPVIAAAILLPISGILGLAIAAVFVMPLVLRHVGGREYAGLARQGRNATAVSVWNALWVSLAFGAGWLLTLPFWLIPPMAVILSVFWWAFAFTRMLRLDAIVEHASPAERAILLKRHNSGFWLIGLVCSLLNLLPPAWIILPVFSGLVYAHYGLDALQRLRQERTIDV
>CP020651.1|AWP86152.1|4105018_4105831_-|competence/damage-inducible-protein-A
MAAESARRIGLIIVGDEILSGRRQDKHFSKVVELLGARGLKLSWAELLPDDRATLAAVLRRSFASGDIVFSCGGIGGTPDDHTRQAAAEALDLPLALHPEAEQAIALRAAEMAAKGQGTADMGTPENQQRLQMGMFPRGCEIVPNPYNRIPGFFVRDHTFVPGFPVMAWPMLEWTLDTRYRALHHQVRHAEHSFLVFDMPESRITPAMVEIEQRWPGVRAFSLPSVGETGGPSHIDLGVKGEPEAAAQALAFLRAEVVRLGGKLAPPAQN
>CP020651.1|AWP86151.1|4104011_4104860_-|IclR-family-transcriptional-regulator
MSRIPNATARGPGSHSDDGAGQHPIAIQVIDRAMRLLDALAAQPEPVTLKELSATTGLHASTAHRILNDLVVGRYVERVDNGLYQLGMRLLELGSLVKGRLNVREAAIGAMRSLHKQTGQTINLSVQQGDEIVYIDRAWSERSGMQVVRAIGGRAPLHLTSTGKLFLSTYDTRLVRAYALRTGLAGHTRNSLTELDRLERELALVRRHGYARDNEELELGVRCIAAGIYDDTGKLVAGLSISAPAERLQDEWIRLLVDAAASISEALGYEPGVNGIHAPAAA
>CP020651.1|AWP86150.1|4099416_4103811_-|dermonecrotic-toxin
MDKDESALRQLVDMALVGYDGVVEELLALPSEESGDLAGGRAKREKAEFALFGEAPNGDEPIGQDARTWFYYPKYRPVAVSNLKKMQAAIRARLEPESLILQWLIALDVYLGVLIAALSRTAISDLVFEYVKARYEIYYLLNRVPHPLAAAYLKRRRQRPVDRSGRLGSVFEHPLWFAYDELAGTVDLDADIYEQALAESIERRMDGEPDDGSLDTAGHDVWRLCRDGINRGEQAIFQASGPYGVVADAGYMRTVADLAYADALADCLHAQLRIRAQGSVDSPGDEMPRKLDAWEIAKFHLAATQQARVDLLEAAFALDYAALRDVRVYGDYRNALALRFIKREALRLLGARRGNASTMPAVAAGEYDEIVASGAANDAAYVSMAAALIAGVLCDLESAQRTLPVVLARFRPLGVLARFRRLEQETAGMLLGDQEPEPRGFISFTDFRDSDAFASYAEYAAQFNDYIDQYSILEAQRLARILALGSRMTVDQWCLPLQKVRHYKVLTSQPGLIARGIENHNRGIEYCLGRPPLTDLPGLFTMFQLHDSSWLLVSNINGELWSDVLANAEVMQNPTLAALAEPQGRFRTGRRTGGWFLGGPATEGPSLRDNYLLKLRQSNPGLDVKKCWYFGYRQEYRLPAGALGVPLFAVSVALRHSLDDLAAHAKSALYKPSEWQKFAFWIVPFYREIFFSTQDRSYRVDVGSIVFDSISLLASVFSIGGKLGSFTRTQYGNLRNFVVRQRIAGLSGQRLWRSVLKELPALIGASGLRLSRSLLVDLYEIFEPVPIRRLVAGFVSTTTVGGRNQAFLRQAFSAASSSAGRTGGQLASEWRMAGVDATGLVESTSGGRFEGIYTRGLGPLSERTEYFIVESGNAYRVIWDAYTHGWRVVNGRLPPRLTYTVPVRLNGQGHWETHLDVPGRGGAPEIFGRIRTRNLVALAAEQAAPMRRLLNQARRVALRHIDTCRSRLASPRAESDMDAAIRIFFGEPDAGLRQRIGRRLQEVRAYIGDLSPVNDVLYRAGYDLDDVATLFNAVDRNTSLGRQARMELYLDAIVDLHARLGYENARFVDLMAFHLLSLGHAATASEVVEAVSPRLLGNVFDISNVAQLERGIGNPASTGLFVMLGAYSESSPAIFQSFVNDIFPAWRQASGGGPLVWNFGPAAISPTRLDYANTDIGLLNHGDISPLRARPPLGGRRDIDLPPGLDISFVRYDRPVRMSAPRALDASVFRPVDGPVHGYIQSWTGAEIEYAYGAPAAAREVMLTDNVRIISIENGDEGAIGVRVRLDTVPVATPLILTGGSLSGCTTMVGVKEGYLAFYHTGKSTELGDWATAREGVQALYQAHLAMGYAPISIPAPMRNDDLVSIAATYDRAVIAYLGKDVPGGGSTRITRHDAGAGSVVSFDYNAAVQASAVPRLGQVYVLISNDGQGARAVLLAEDLAWAGSGSALDVLNERLVTLFPAPV
>CP020651.1|AWP86149.1|4098345_4099323_+|ABC-transporter-substrate-binding-protein
MPPISRKLSALFAAVALTGAGTALAEYPERPVNMVVPFAAGGPTDNVARSLAESMRPTLGETVVVENKGGAGGTIGTTQVARAQPDGYSILLMHAGFSTAPSLYKNPGYEPYTSFEPIGLVVDVPMTIIARGDFPPNNIKELAEYVKKNADKISLANAGIGAASHLCGTMLVEALGVNLLTIPYKGTAPAMNDLLGKQVDLMCDQTTNTTQQITGGKVKAYAVTSLKRVPTLPDLPTMDESGYKGFEVGIWHGMWAPKGTPKPVVDKLVKSLQAGLADPKFQERMKQLGAEVLTNEANPEALQAKVKQQVPQWAELFKKAGVEKQ
>CP020651.1|AWP86148.1|4097380_4097959_-|Phasin-(PHA-granule-associated-protein)
MSAIPQQVLARQKATVNSLVAAQSAMFAGFEKLVDLNLKVVRATLDEVAQQSQQAAELKDPQDVASFTSGLVQPGAEKALAYGKHVYDIVAGVQAELAQLAEAQIAEGQQQLTEAVEQFSKNAPTGSESAVALIKSSLATANSAYDSLTKAAKQAAEVAESNLNAAANASFKAASDAAEVATKAAGRNRRAA
>CP020651.1|AWP86147.1|4096183_4097233_+|dihydroorotate-dehydrogenase-(quinone)
MSILFHAYPLARPALFAMDAETAHEVTLAQLQRAYDCGLTRKLLHAQPEAPATLMGLSLRNPVGLAAGLDKNGAHIDALGNLGFGFVEVGTVTPRAQPGNPKPRMFRLPRANALINRLGFNNQGLDAFIANVQRSQWRSQGGILGLNIGKNADTPIERAAEDYLIGLAGVYPHADYVTVNISSPNTKNLRALQGGDELSALLGQLQERRLALADQHQRHVPLAVKIAPDLSDDQIDAIAEILPRHGIDGVIATNTTLARDAVQGLPHAEEAGGVSGAPVHELSLRVIERLRSRLGDAVAIIGVGGILSGRQASEKMAAGAQAVQLYTGLIYRGPALVGECVRALAQGSR
>CP020651.1|AWP86146.1|4095408_4096143_+|arginyltransferase
MPDMSQLKELPFSTLQFYATAPYPCSYLPGRQARSQVAAPGHLINAGTYSQLVEQGFRRSGLFTYRPHCDNCHACVPVRVDAARFEPNRTQRRAWRSHQALRAFVAELAWSPEHYDLYTRYQQGRHPGGGMDEDSRTQYAQFLLTTRVNTRLVEFRTPQGQLAMISIIDVLDDGLSSVYTFYDPDMAGSLGTYSILWQIEQCRTLDLPWLYLGYWIADSRKMAYKANFRPLQMHVDGAWRETPP
>CP020651.1|AWP86156.1|4108863_4109193_-|hypothetical-protein
MSDRDLYVYGAILLLTLCSVLTRAGFMLFGDYIPLPDGVRRALRYAPAAALTAIVVPDLLPWKAGLGPAFDYKLVAGVLAIMAFLRTRSAVLVIVVGMVALWGLRWLAG
>CP020651.1|AWP86157.1|4109195_4109864_-|hypothetical-protein
MRAITPALIATGTWGMVTGVAMVKSGLTESMALAMTLLMYAGSAQLTSLPLIATGAPLWLIFAAGFVVNLRFLIFGAALHPYFRHMSWPRRLGLGYFTTDMGFVLFMPRFGDAAERGTREQLWFFLGTVAPGWMVWQVTSIVGIYLGSLVPEAWSLDFAAVLALLAITVPLANSKPMLVSMLAAGMVAWVGQLLPLRLGLAAAVVAGIVAGIWAERFFKGRT
>CP020651.1|AWP86158.1|4110127_4111048_+|branched-chain-amino-acid-aminotransferase
MSMSDRDGFIWYDGKLVPWREATTHVLTHSLHYGLSVFEGVRAYETAAGTAIFRLQDHTNRLFNSAHIYQIPLPYDRDTLNEAQREVVRANGLASCYLRPLAFYGSEKMGVSPKGAQVHVAIAAWPWGAYLGETALAQGIRVKVSSFARQHVNVTMPRAKVATTYANSIIANAEALQDGYDEALLLDTEGFVAEGAGENIFIVKDGVLCEPEIASALTGITRSTIHALAADLGLRVVTKRLTRDDVYIADEAFFTGTAAEVTPIREVDNRQIGAGRRGPVTEKLQQAFFDLVNGRNPKYQHWLTPV
>CP020651.1|AWP86159.1|4111094_4111307_+|zinc-finger-domain-containing-protein
MTAAAQAAVPAHDAIEVGAEDLPVYCPGPKAPLWSMHPRVFLDVTHTGQASCPYCGAAYRLKPGTVVHGH
>CP020651.1|AWP86160.1|4111329_4111752_+|DUF4440-domain-containing-protein
MFATPDEAEHAFYEALEHADLDRLMQVWSDDEEIACIHPGGLRIVGHTAVHESWQQVLANGPLHLRPLRPLVMQSMMCAVHVLVEQVTVMTREGAQFANCYATNVYHKGPAGWRMVLHHASQAPAEAGVLDLHDFPDRLH
>CP020651.1|AWP86161.1|4111768_4112869_+|alpha/beta-hydrolase
MAASRIDLTPCPVPPWLPDRHSQTVYAAALAQYHRIAFVRERVDTPDTDFVDFDWTGPGLFPHKTAEGAAPAGPAPQGNGRIAAARWITATDWASLPQTADTPALILFHGLEGGSASRYAQSIAHYFRARGWIVVIAHFRGCSGVPNRLARAYYSGDSAEVGFMLDTVRARIPHARWHAVGVSLGGNALLKYLGEHHDEASWLAAAAGVSVPLDLVAGGKALCTGFIARRIYTAYFLKTMRRKVLEKAKRFPGAIDVIRIAHARDLRDFDDAYTARMHGYRNALDYWTRASSKPWLAHIKTPTLVLNARNDPFLPESALPIPAECSDSVLLHQPAEGGHAGFPTGPFPAHLNWLPQRLGRFFEMGS
>CP020651.1|AWP86162.1|4112965_4114483_-|peptidase
MNRWNLTFSPSLGRRALAAALSLALGLPVAPAVGQPSGLPSMGAASASELSPMLERQLGDAIMAQGRRDPTYINDPELRQYLTTMGRKLASFAPGAAPHVEMFGVRDPEINAFAMPGGYIGVNTGLIVSSASESELAAVLAHEIGHVAQRHIARGMTQQNQNSMVMLASLAGALLAALAGGGGNLAMGVAAFGQAAAINRQLGFSRDAEREADRTGLQMLAKAGYDPDGMAQMFSRLMNASRLNEGMGGGAWASTHPLSIDRMSDVQNRIRGLPGSRHVDSDDFWFIRAKMRVAQGRDALSLRTAQQQLQDESRALSGVRQAAAFYGLALYAFQRNDLAQARAFLEQAGAGGRSSPQMARLAIDVAVAAKDNDQALALAQAAVKRWPDRKALGIAYAQALQAAGRHADAQAYLRERARQWGGDEPSLYQLLAQSEERTGHPVDARRNMARYYDLTGAYASAESQLQQARGLSNDFYEQSQIDVSIREIKQKLADERQLLERFKSG
>CP020651.1|AWP86163.1|4114558_4115398_+|UTP--glucose-1-phosphate-uridylyltransferase
MQVVRKAVFPVAGMGTRFLPATKAMPKEMLPVVDKPLIQYAVEEAVAAGITDLIFVTGRNKRAIEDHFDAAPELETDLEAKGKHELLALVRDILPAHVNCLYIRQSAPLGLGHAVLTAAPAVGNEPFAVLLADDLIDADTPVLKQLIDVAVARQGSVLGVQEVPREDTRKYGIVASQPVDARTERVTHIVEKPAPEQAPTTLAVVGRYVLEAAIFDHLRATTVGAGNEIQLTDGIAALLRERDVYAHRYDGKRYDCGSKAGMFQATVALGRKYHGLIPE
>CP020651.1|AWP86164.1|4115419_4116301_-|hypothetical-protein
MTRMDWLEWLIPWEFSPTLVAAFVVAIVLFVRGQRVHHVTAARQWLFWSGMVLLYLSMHTRLDYYAERMFFIHRAQHLVLHHLGPLLVMAAFPGSAMRAGLPMAWRVRLRDFLRTGTGRALAAVLTHKVFVPTLFVFLVLVWLLPSVQFYSMLDWRLYRLMNWSVVISGFMYWNLILDRRPSPPAAMTPGGRVLSPALTMAPQMVAGAVIAFTERDLYPLFELCGRAIAMSAQTDQTIGGLTMWIPAALVEVVGLLVALGTLMRLSGKGRLRPQDRAARARQRAAGSPTSPAA
>CP020651.1|AWP86165.1|4116382_4117477_-|porin
MRRLLVVAAMAAGSSSVFWSVAPARAANQLELYGVVDVGLATTRVSGLGTRQQVLGGGQTDNLWGLRGTEELDGGWRASFGLESGFDAANGTRNDDARLFDYGTWVGLGHAGVGELSLGRQQSIGLQYGGQLEIASWRDMGMGALFKASDNYRVNNLVNYLSPEFSGWQWGVGYAFDVESGDTGRFDRSPAFSTGLKYEDGPLLAAFTWDKLNLHDTSATGGRSPQALQAGFTYDFEALKMALAWSRQRNGFVGLNGGGQIGLGPEPFAHGGAINAWLLGLEVPVHGNGAWLVQGSMARPDWHWANGQQASKAYVVTLGYRQDLSARTSLYAYGGYMKGYDPEDPFASDVGRATRFGVGMTQRF

Crispr_ID: CP020651_8

• CRISPR_ID: CP020651_8
• CRISPR_location: 4397769-4397862
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP020651_8

Consensus_repeat	Method
GTGCCTGTCCCCGCCGGGACAGGCAC	CRISPRCasFinder

spacers of CP020651_8

>8.1|4397795|42|CP020651|CRISPRCasFinder
CCGGGCCCAGGAAAACCCCCACGCTGCGCCCGCTGTGCGGGC

CRISPR arrays and Neighbor proteins around CP020651_8

CRISPR arrays

The CRISPR arrays of CP020651_8

>merge|CP020651|8|4397769-4397862|CRISPRCasFinder
GTGCCTGTCCCCGCCGGGACAGGCACCCGGGCCCAGGAAAACCCCCACGCTGCGCCCGCTGTGCGGGCGTGCCTGTCCCCGCCGGGACAGGCAC

>CP020651|8|8|4397769-4397862|CRISPRCasFinder
GTGCCTGTCCCCGCCGGGACAGGCAC	CCGGGCCCAGGAAAACCCCCACGCTGCGCCCGCTGTGCGGGC
GTGCCTGTCCCCGCCGGGACAGGCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP020651.1|AWP86406.1|4394033_4394789_-|hypothetical-protein	unknown	unknown	gnl|CDD|223930
CP020651.1|AWP86405.1|4392605_4393838_-|CoA-transferase	unknown	unknown	gnl|CDD|367110
CP020651.1|AWP86402.1|4389801_4390779_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176106
CP020651.1|AWP87317.1|4404604_4404913_+|sugar-translocase	unknown	unknown	gnl|CDD|377229
CP020651.1|AWP86410.1|4398507_4398852_-|TIGR01244-family-protein	unknown	unknown	gnl|CDD|225984
CP020651.1|AWP86408.1|4395414_4397538_-|elongation-factor-G	unknown	unknown	gnl|CDD|234569
CP020651.1|AWP86404.1|4391827_4392613_-|enoyl-CoA-hydratase	unknown	unknown	gnl|CDD|181723
CP020651.1|AWP86403.1|4390789_4391761_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270234
CP020651.1|AWP86413.1|4401451_4402111_+|hypothetical-protein	unknown	unknown	gnl|CDD|224199
CP020651.1|AWP86401.1|4388503_4389676_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173841
CP020651.1|AWP86415.1|4403129_4403585_-|hypothetical-protein	unknown	unknown	gnl|CDD|226610
CP020651.1|AWP86416.1|4403581_4404685_-|hypothetical-protein	unknown	unknown	gnl|CDD|212118
CP020651.1|AWP86412.1|4400540_4401455_+|EamA-family-transporter	unknown	unknown	gnl|CDD|223769
CP020651.1|AWP86409.1|4397948_4398419_-|universal-stress-protein	unknown	unknown	gnl|CDD|366180
CP020651.1|AWP86417.1|4404872_4406492_-|dolichyl-phosphate-mannose--protein-mannosyltransferase	unknown	unknown	gnl|CDD|224720
CP020651.1|AWP86407.1|4394899_4395418_+|methyltransferase	unknown	unknown	gnl|CDD|224204
CP020651.1|AWP86399.1|4386189_4387383_-|acetyl-CoA-acetyltransferase	unknown	unknown	gnl|CDD|180775
CP020651.1|AWP86411.1|4398951_4400352_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224089
CP020651.1|AWP86400.1|4387448_4388477_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|366103
CP020651.1|AWP86414.1|4402200_4403124_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|378820

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP020651.1|AWP86406.1|4394033_4394789_-|hypothetical-protein	gnl|CDD|223930	COG0861, TerC, Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism].	1.14565e-78
CP020651.1|AWP86405.1|4392605_4393838_-|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	8.36236e-118
CP020651.1|AWP86402.1|4389801_4390779_+|LysR-family-transcriptional-regulator	gnl|CDD|176106	cd08414, PBP2_LTTR_aromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LTTRs involved in degradation of aromatic compounds, such as CbnR, BenM, CatM, ClcR and TfdR, as well as that of other transcriptional regulators clustered together in phylogenetic trees, including XapR, HcaR, MprR, IlvR, BudR, AlsR, LysR, and OccR. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	2.33368e-60
CP020651.1|AWP87317.1|4404604_4404913_+|sugar-translocase	gnl|CDD|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	1.61408e-10
CP020651.1|AWP86410.1|4398507_4398852_-|TIGR01244-family-protein	gnl|CDD|225984	COG3453, COG3453, Uncharacterized protein conserved in bacteria [Function unknown].	3.40043e-35
CP020651.1|AWP86408.1|4395414_4397538_-|elongation-factor-G	gnl|CDD|234569	PRK00007, PRK00007, elongation factor G; Reviewed.	0
CP020651.1|AWP86404.1|4391827_4392613_-|enoyl-CoA-hydratase	gnl|CDD|181723	PRK09245, PRK09245, crotonase/enoyl-CoA hydratase family protein.	2.06175e-156
CP020651.1|AWP86403.1|4390789_4391761_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	2.06741e-117
CP020651.1|AWP86413.1|4401451_4402111_+|hypothetical-protein	gnl|CDD|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	4.25651e-32
CP020651.1|AWP86401.1|4388503_4389676_-|acyl-CoA-dehydrogenase	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	6.87275e-84
CP020651.1|AWP86415.1|4403129_4403585_-|hypothetical-protein	gnl|CDD|226610	COG4125, COG4125, Predicted membrane protein [Function unknown].	2.35069e-54
CP020651.1|AWP86416.1|4403581_4404685_-|hypothetical-protein	gnl|CDD|212118	cd10807, YdjC_like_3, uncharacterized YdjC-like family proteins from bacteria. This subfamily contains many hypothetical proteins, and belongs to the YdjC-like family of uncharacterized proteins from bacteria. The YdjC-family is represented by an uncharacterised protein YdjC (also known as ChbG) encoded by the chb (N,N'-diacetylchitobiose, also called [GlcNAc]2) or cel operon in Escherichia coli, which encodes enzymes involved in growth on an N,N'-diacetylchitobiose carbon source. The molecular function of this subfamily is unclear.	1.3947e-92
CP020651.1|AWP86412.1|4400540_4401455_+|EamA-family-transporter	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	8.05606e-10
CP020651.1|AWP86409.1|4397948_4398419_-|universal-stress-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.38587e-30
CP020651.1|AWP86417.1|4404872_4406492_-|dolichyl-phosphate-mannose--protein-mannosyltransferase	gnl|CDD|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	2.23603e-50
CP020651.1|AWP86407.1|4394899_4395418_+|methyltransferase	gnl|CDD|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	1.52093e-44
CP020651.1|AWP86399.1|4386189_4387383_-|acetyl-CoA-acetyltransferase	gnl|CDD|180775	PRK06954, PRK06954, acetyl-CoA C-acetyltransferase.	6.15168e-175
CP020651.1|AWP86411.1|4398951_4400352_-|GntR-family-transcriptional-regulator	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.52472e-110
CP020651.1|AWP86400.1|4387448_4388477_-|acyl-CoA-dehydrogenase	gnl|CDD|366103	pfam00441, Acyl-CoA_dh_1, Acyl-CoA dehydrogenase, C-terminal domain. C-terminal domain of Acyl-CoA dehydrogenase is an all-alpha, four helical up-and-down bundle.	3.23873e-12
CP020651.1|AWP86414.1|4402200_4403124_+|alpha/beta-hydrolase	gnl|CDD|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	2.97616e-21

Protein sequences

>CP020651.1|AWP86408.1|4395414_4397538_-|elongation-factor-G
MTRRTSIERYRNIGISAHIDAGKTTTTERILFYTGITHKLGEVHEGAATMDWMEQEQERGITITSAATTAFWRGMAGNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYDSVGGVQPQSETVWRQANKYGVPRIAFVNKMDRVGADFFRVQRQIVERLKGDAVPIQIPVGAEDHFEGVVDLVKMKAIIWDDASQGVRFEYRDIPPELQAQAEQWREKMIEKAAEANEALLEKYLSGQPLSEDEIKSGLRARTVANEIVPMLCGSAFKNKGVQAMLDAVIDYLPSPADVPAIIGHDERDREIERHPADDEPFSALAFKIMTDPFVGQLIFFRVYSGVVKSGDSVLNPLKSKKERLGRILQMHANERREISEVYAGDIAAAVGIKEITTGDTLTDPAHVIILERMTFPEPVISQAVEPRTKADQEKMGIALNRLAQEDPSFRVRTDEESGQTIISGMGELHLEILVDRMKREFGVEANVGKPQVAYRETIRSTVTDVEGKFVKQSGGRGQYGHVVLKLEPQEQGKGYEFVDAIKGGVVPREFIPAVDRGVRETLNTGVLAGYPVVDVKVTLVFGSYHDVDSNENAFRMAASMAFKEGMRRAKPVLLEPMMHVEVETPEDFTGNVMGDLSSRRGMVQGMEDIAGGGGKLVRAEVPLAEMFGYSTSLRSLTQGRATYSMEFKHYAEAPRQVAEQIIAARGSGAAARG
>CP020651.1|AWP86407.1|4394899_4395418_+|methyltransferase
MDTVWMEIWTTVRNEFADIPDVAEATRIVLRLGMAVALGGLLGYERERSGKAAGLRTHMLVALGAALFVLVPLQGGMEVGDLSRVLQGVIAGIGFLGAGAIIKLGNEGEIRGLTTSAGIWLTAAIGVAAGMGREATALASTLIALFVLAALRRLEKRIAARDDKRVVAQPPP
>CP020651.1|AWP86406.1|4394033_4394789_-|hypothetical-protein
MDYLVSLAQQPAAWAALATLIAMEVVLGIDNLIFISILTNKLPPQHQTKARRIGIGMALILRLALLGTVAFIVQLTQPVFELFGHGFSWRDVILVAGGLFLVWKATKEIHHHVDPNPGDDMFGGKAATLGFAAAVAQILMLDLVFSIDSIITAVGMTEHIPIMFVAVIVAVAVMLLAAEPLARFIERNPTVVMLALAFLMMIGMTLIAEGFGAHVPKGYIYAAMAFSALVEGLNMMARRAREGRGAGAAGG
>CP020651.1|AWP86405.1|4392605_4393838_-|CoA-transferase
MSGPLEGVRILDVTTVLMGPYATQILGDLGADVIKVEPPAGDNVRGIGPGRHADMGGIFLHANRSKRSIALDLKNPAGREALLKVAATCDVLVYNVRPQAMARLGLSYAEVAQANPSILYVGMYGYDQRGPYAARAAYDDLIQGAVGIPSLSVEAGSDIPRYAPSAMVDRIVGISAANAVTAGLYHRARTGQGQAIDVPMFETMAHLILGDHMMGQTFEPPLGPPGYPRILNADRRPYATRNGHICVLLYADKHWKAFFELIGQPGRDAADPRFRDIGTRTQHIHAIYRLVSDAIASRTTEEWLAAFEAADIPAMPVHTMASLLRDPHLEAIGFFGMVDHPSEGAVRMMAVPSRWSGTPPQPRGHAPRLGEHSVDVLKEAGYDDEAIAALVRNGAAIAAARQLPEGTDHD
>CP020651.1|AWP86404.1|4391827_4392613_-|enoyl-CoA-hydratase
MTDFLRHERHGGVLLLTMDRERTRNALSDADAVEALVQACARIGADLSVRAVVLTGSHGVFSSGGNLKTLSDTVGAGLGEPVHSRQAYRSGIQRIPLALYNLEVPTIAAVNGPAIGAGCDLACMCDIRLAARQASFAESFVKLGLTPGDGGAWLLPRIVGMSRACELAFTGRSIDAARARELGLVSEVFDADALLPAALALAQEIAQHSGHALRLTKRLLREGQHTRLDTLLELSAGFQALAHHTQEHAGALDAHLSRKRG
>CP020651.1|AWP86403.1|4390789_4391761_-|ABC-transporter-substrate-binding-protein
MHSRTLALALLSVAALAQGGSARAASDYPAHPVKIIVSLPPGSGADTTARFLSKHLAERFKQPFVVENRPGGNSFIAAQAVATAPPDGYTLFVASNSPMTTNAAVFKNLPYDAVKDFAPVAPIARFPMALVVPANSPYRSVADLVAAARAAPGQLNFASGTATYQVVLELFHEQNGIKATHVPYKGTSAALADVAGGVVQYSVADVSAALPLIRGGKLRPLAVTSTRRIKDLPDVPTMQESGNKGFEAYAWTAAFFPAKVDPAIVARVSDAVQALVRSQEGKAFMEQLGGEPFVGGPDTLAAFQRDELASMRRIAKLANIQQE
>CP020651.1|AWP86402.1|4389801_4390779_+|LysR-family-transcriptional-regulator
MWTGQYIVHIASPAHHWRRAVELRQLKQLLVLSETLNFHRAAERLHMAQPPLSTAIKKLEQELGVQLFERLPAGLQPTPAAEVVLRYARATLFYADEIQRAAQEGASGKQGMLKVGFVGSSIYSLMPQLLSAFRKDYPRVDLVIEESTTVDLLRRLDAHTLDVALVRFPVLEPSTARITLLQADHLMLAVPAGSRYAQRDDVALDELADEPFIGYSRTHVPGMHALIMYAFQQYGVVPHIAQEAIQVQTILSLVESGLGLAIVPKVACRQAGSGVRLVNVPQLAETIKVGIALAVHPDNATPTTANFVDMACRLMQTEPAAGQAR
>CP020651.1|AWP86401.1|4388503_4389676_-|acyl-CoA-dehydrogenase
MGAILGTIIEALQLAAIPAHDEALRPAVRAFLDEALREMPADRRARSWMGHDAEFSRALARQGWLGLTLPVEYGGAGRSNFARFVLSEELLAAGAPVSAHWIADRQTAPLILRFGSPAQRAFYLPRIIRGEAFFAIGMSEPDTGSDLASVRTRATPVADGWLLNGRKIWTTNAHRSHYMCALVRTSGAPEDRHRGLSQMIFDLALPGIEIRPIRDIAGDAHFCEVLFDNVLLPHDALVGEEGSGWRQVMAELALERSGPERIYSSMVLLDGWLAHLRRDAAPQRAQVCLAGRLAARLAVLRSMSLAVSQRLEQGADASLAAVLVKDLGTEFEQAVPELIGQALHASPQPAPDDVLMRTLAYLTLINPTFSLRGGTRHILRGIIARELGLR
>CP020651.1|AWP86400.1|4387448_4388477_-|acyl-CoA-dehydrogenase
MVSTMQQDLYETFARALAGLCPLERVRELEAAADPRAGAARAWNEVDALGYGDALSPAEHGGAGLSLADAEGLLRAAGAMALPFPFADTLLARALLRAAGQAVPDGPIALGVALPHGAGWRCAPIAGVALAQAVAVEHDGCLALWPAPDAVQPGLFRPRASGAPAWRGTPAQAGRAGAPAGAVQAWRNAADAAGMAGAMQAVLDRCVAYVQERQQFGRALGRFQAVQQDISMLAEQVAAVAMAARLACASGVLFPDPALAACARLRACEAVPVVCALAHAVHGAIGITEELPLGLYTARLHEWRATGMSEDDCAELLGRRVLADGERTLLDVVRGMVSAAHA
>CP020651.1|AWP86399.1|4386189_4387383_-|acetyl-CoA-acetyltransferase
MSVHPDPVVIVAARRTPIGAFQGALAHYSAPQLGAHALAAAVRQAGLQPDAAQEALMGCCLFAGLGQAPARQAVLGAGLPTDVQATTLSKMCGSGMKAAMLAHDMLRAGSADVVLAGGMESMSNAPHLIPKARQGYRLGDGQLLDHMYRDGLQDAYEGRLMGHYADLAAREYGFSREQQDAYAHESVLRAQRSVAEGEFAEEIAPIAGLARRGAPAAMVAVDETPGLCDVSRLASLKPVFNADGTVTAGNASSISDGAAALVLTRQAHAERLGLAPQARIVGHATAALPPGQFPAAPVRAIARLFERVGWDRDSVDLFEINEAFAVVTMIALRELGLPAERVNVNGGACALGHPVGATGARLIVTLMHALRRRGLRRGVACLCLGGGEATAIAVERA
>CP020651.1|AWP86409.1|4397948_4398419_-|universal-stress-protein
MFKKILIPTDGSPLSAQAANAGICFARSTGAEVVALHVTQPFAATIGFDGMAAAYAITDEDYEKASAEQAEKYLKLILDRAETAGVKAESRAVSNFNVADGIVQAAGEAGCDLIFIGSHGRSGLSRLLLGSVTAKVLSLAHTAVLVYRVKEDKDKK
>CP020651.1|AWP86410.1|4398507_4398852_-|TIGR01244-family-protein
MSAAIKPLTENFAVAPQLGPADMADVAAAGYKSVIINRPDFEGGPDQPTAADVSQAAQALGLQVEYQPVVGSAMTAADVARFAELLRTMPGPVLAYCRTGTRCTNLFAAAQQLG
>CP020651.1|AWP86411.1|4398951_4400352_-|GntR-family-transcriptional-regulator
MRQADATLVTQLADDLARRIDEHGLRPGTRLPSIRRMAEQSGVSRFTVVEAYDRLVARGLVQSRRGAGFFVRARSASLTALASARVPQAAPETPVRVDVSWLLRNMFRETAAGMPGGAGLLPPEWLDPDMVAAAVRAVGRTVRGNLVSYGSPQGYAPLRQQLASMLQADGVPAHPERNLLTTNGVTHGLDIVARHLIKPGDTVLVEDPAWFVIFGRLAAFGARPVGVPRGPDGPDLAMLDRLAAEHKPRLYIINGAVHNPTGHTLSAGAAYDILRLAERHDFMVVEDDTYADLHPGGAMKLAALDRLERVILVGGFSKMLAASLRVGYIAAGAETLQRLTDLKMLAGLTSPELGERVVHRVLVEGQYRRHIERVRARVNEARLRSIQALQQLGLSVPHEPHAGMFVWADCGRDSEPVARNAAERGMLLAPGTLFSPSGAPSTMLRFSVAMVDTPGIWQSIAAVMAQ
>CP020651.1|AWP86412.1|4400540_4401455_+|EamA-family-transporter
MSPPSAQASAPSASPHAPSWEGYGYGLIGVLVFALTLPMTRLAVGELSPLLVGLGRALLAAVPAAALLWLTRSRRPDRAEWSGIVLAAVGIVVGWPVASTLAMASVPAAHGAVFNGLLPLSTAVFAAWRSGERPSPAFWSFAVLGAVLVAGYALRQGHGALQPGDLWLLLAVVLGGMGYAEGARASRTLGGWRTICWALVVSVPALLPAVLWLAHDAAWPSLPVAGAFAYLAFGSMFLGFFAWYRGLAIGGIARVGQIQLLQPFLTVVAAALLFNEQVEPITYVFAVAVVLVIAGGRRAMVRKA
>CP020651.1|AWP86413.1|4401451_4402111_+|hypothetical-protein
MIGSDLSSLDQAPLASLSVLMPLVLFTLVNSLTPGPNNVMLASSGLTFGFRRTIPHLLGISVGFSIMLLMVGLGLGATLERLPWLYSTLKYGGAAYLLYLAWKIATSGPMESGAERGKPLTFIQAALFQWVNPKAWVMIVSVVATYTPQHGYFANLIIATLVCGVVNLPSVGVWAAFGMALRRWLHRPAAVRAFNVGMAVLLVVSLYPVGLDLLALYTG
>CP020651.1|AWP86414.1|4402200_4403124_+|alpha/beta-hydrolase
MVSLPFRLSWRRMAAVLLLAAGALGFNQLDAWQRQAIFSPQTDQQRWWREPPAGTEVFDLALPNGDKVHAWYWQSPRRDAPTVLYLHGARWNLNGSAFRMEGWTRMGYSMLAIDYRGFGQSTPLLPSEQSASQDAAAALQELARRQPDPARRFIYGHSLGGAIAIDLAARPDLPPFAGLIVESSFTSIGAMLGTMKWGWVPGATLLVTQPFASVDKLAALTTPMLLLHGTADRVVPHTMSDELYRAAQQVPADLKRLVKIEGASHSGAIRSGRIYEDAVADFVRDAGRGYAGRQGAPTPLTASRPGT
>CP020651.1|AWP86415.1|4403129_4403585_-|hypothetical-protein
MSSSSKQTPKTIKERFLHAFFFEIIAIGLSAPVAAWAMDQPLFDMGVLTAVIAWIALLWNMVYNAGFERLERRFGVVRTMPVRVAHAVGFELGLVLIIVPLAAWWLAISFWEAFMLDIGLLMFYLPYAFFYNLAYDKLRARWWGRIEPAGA
>CP020651.1|AWP86416.1|4403581_4404685_-|hypothetical-protein
MTSERYDEGQQPAHHVGPQRGQAGPFHAGDRDGPMGGGRGASDGNEPGNLSQQAAHVEEVSPLRNQAGDVRCRRIAVCGDDFGMNEAIDGALIELAGAGRLSAVSCMPLAPAFAADAPALARLDVDLGVHVDFTEAFAGAAPAAPGLAALLWRAYAGQLDPDWIDARLASQFDAFERAFGRAPDYVDGHQHVHQLPGILPRLRALLKRRYAGQRIWLRHTAPGLQFGLPLAEAAKARLIGALGAGALARAAGQEGWQTNRRMLGVYGFTGGPRRYAGLLHHWLMNARDGDLLMCHPGWPQVHGAAHASQRAAEYEVLAHPELGTWLARNGLRIVRLSQVRGRQASQESGKVRNVPHSGSFRRLASRL
>CP020651.1|AWP87317.1|4404604_4404913_+|sugar-translocase
MEWAGLPPLGANVVGWLLAFVVSFTGHFRLTFRHLAASWTIAARRFFLVSALGFAINELSYAWLLHATSLPYDVLLALVLIGLAFLTFVASRLWAFRHRHAP
>CP020651.1|AWP86417.1|4404872_4406492_-|dolichyl-phosphate-mannose--protein-mannosyltransferase
MTLATRSMQPHAVSPGQARSWPLPAAGWLLLAVGVWLAFLSWMRPLALPDEGRYAGVAWDMLRNGSFAVPLIDGMPYFHKPPLYYWLAELSFRLFGVNEWAARLPSALAAWASAVALYLFVRRHRDAASATLCVLVLATLPLFFGGAQYANMDMLVAGMITLCVLAGADTALRVRGGQAWRAMALATGVCAALAMLAKGLIGLVLPGAILLAWLAWRRDWRGLRALLWPPAILAFAVVAVPWFWLMQVRYPGFFQYFFVHQHFERFAQTGFNNVQPFWFYLPVIAGLALPWSLWAGGLLRKQFWAADADPDGLRRLALVWLAVIVAFFSMPQSKLVGYIMPVLPPLAFLLAEVVMGALRDPAVARATRRMARVSALVAVAICVTAVFVASFNARGSSRELALSLRGELRPNDTLVALHTYPFDLQLYAHAARPMWVVDDWSNPEIPKRDNWRRELYDAVQFEPALGERLLVSADTFQQRLCQAPEGSRYWVWGTAADEEAYAPLRGQAARFADARRSLWLVLVDEAFKGRVCDGTPTGG

Crispr_ID: CP020651_9

• CRISPR_ID: CP020651_9
• CRISPR_location: 4533243-4533323
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP020651_9

Consensus_repeat	Method
GTGCCTGTCCCCGCCGGGACAGGC	CRISPRCasFinder

spacers of CP020651_9

>9.1|4533267|33|CP020651|CRISPRCasFinder
GCCTGCAAGATTTCATGGCATCTGCCCGTGCGT

CRISPR arrays and Neighbor proteins around CP020651_9

CRISPR arrays

The CRISPR arrays of CP020651_9

>merge|CP020651|9|4533243-4533323|CRISPRCasFinder
GTGCCTGTCCCCGCCGGGACAGGCGCCTGCAAGATTTCATGGCATCTGCCCGTGCGTGTGCCTGTCCCCGCCGGGACAGGC

>CP020651|9|9|4533243-4533323|CRISPRCasFinder
GTGCCTGTCCCCGCCGGGACAGGC	GCCTGCAAGATTTCATGGCATCTGCCCGTGCGT
GTGCCTGTCCCCGCCGGGACAGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP020651.1|AWP86527.1|4538508_4538958_-|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit	unknown	unknown	gnl|CDD|235777
CP020651.1|AWP86528.1|4539047_4539482_-|type-II-3-dehydroquinate-dehydratase	unknown	unknown	gnl|CDD|235443
CP020651.1|AWP87328.1|4534104_4535046_-|carbohydrate-kinase-family-protein	unknown	unknown	gnl|CDD|238917
CP020651.1|AWP86531.1|4541572_4542166_+|esterase	unknown	unknown	gnl|CDD|225692
CP020651.1|AWP86515.1|4523222_4526150_+|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl|CDD|235966
CP020651.1|AWP86517.1|4528402_4528978_+|YggT-family-protein	unknown	unknown	gnl|CDD|376765
CP020651.1|AWP86518.1|4528985_4530449_-|D-alanine--poly(phosphoribitol)-ligase	unknown	unknown	gnl|CDD|341267
CP020651.1|AWP86514.1|4519410_4522917_+|pyruvate-ferredoxin-oxidoreductase	unknown	unknown	gnl|CDD|237279
CP020651.1|AWP86525.1|4536210_4537134_-|ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl|CDD|283886
CP020651.1|AWP86520.1|4531594_4531720_-|hypothetical-protein	unknown	unknown	unknown
CP020651.1|AWP86523.1|4533427_4533931_-|lipoprotein	unknown	unknown	gnl|CDD|225675
CP020651.1|AWP86519.1|4530459_4531587_-|membrane-bound-O-acyltransferase	unknown	unknown	gnl|CDD|274974
CP020651.1|AWP86516.1|4526171_4527374_+|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl|CDD|235968
CP020651.1|AWP86521.1|4531716_4532844_-|teichoic-acid-biosynthesis-protein	unknown	unknown	gnl|CDD|368189
CP020651.1|AWP87327.1|4527691_4528264_+|histone	unknown	unknown	gnl|CDD|237855
CP020651.1|AWP86524.1|4535057_4536185_-|hypothetical-protein	unknown	unknown	gnl|CDD|378759
CP020651.1|AWP86522.1|4532869_4533109_-|acyl-carrier-protein	unknown	unknown	gnl|CDD|223314
CP020651.1|AWP86529.1|4539560_4540109_-|thioredoxin	unknown	unknown	gnl|CDD|239264
CP020651.1|AWP86526.1|4537152_4538499_-|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	unknown	unknown	gnl|CDD|236307
CP020651.1|AWP86530.1|4540191_4541562_+|UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl--meso-diaminopimelate-ligase	unknown	unknown	gnl|CDD|130153

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP020651.1|AWP86527.1|4538508_4538958_-|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit	gnl|CDD|235777	PRK06302, PRK06302, acetyl-CoA carboxylase biotin carboxyl carrier protein.	2.94729e-77
CP020651.1|AWP86528.1|4539047_4539482_-|type-II-3-dehydroquinate-dehydratase	gnl|CDD|235443	PRK05395, PRK05395, type II 3-dehydroquinate dehydratase.	2.95712e-86
CP020651.1|AWP86531.1|4541572_4542166_+|esterase	gnl|CDD|225692	COG3150, COG3150, Predicted esterase [General function prediction only].	8.39901e-54
CP020651.1|AWP86515.1|4523222_4526150_+|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl|CDD|235966	PRK07207, PRK07207, ribonucleoside-diphosphate reductase subunit alpha.	0
CP020651.1|AWP86517.1|4528402_4528978_+|YggT-family-protein	gnl|CDD|376765	pfam02325, YGGT, YGGT family. This family consists of a repeat found in conserved hypothetical integral membrane proteins. The function of this region and the proteins which possess it is unknown.	2.04276e-07
CP020651.1|AWP86518.1|4528985_4530449_-|D-alanine--poly(phosphoribitol)-ligase	gnl|CDD|341267	cd05945, DltA, D-alanine:D-alanyl carrier protein ligase (DltA) and similar proteins. This family includes D-alanyl carrier protein ligase DltA and aliphatic beta-amino acid adenylation enzymes IdnL1 and CmiS6. DltA incorporates D-ala in techoic acids in gram-positive bacteria via a two-step process, starting with adenylation of D-alanine that transfers D-alanine to the D-alanyl carrier protein. IdnL1, a short-chain aliphatic beta-amino acid adenylation enzyme, recognizes 3-aminobutanoic acid, and is involved in the synthesis of the macrolactam antibiotic incednine. CmiS6 is a medium-chain beta-amino acid adenylation enzyme that recognizes 3-aminononanoic acid, and is involved in the synthesis of cremimycin, also a macrolactam antibiotic. The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions.	0
CP020651.1|AWP86514.1|4519410_4522917_+|pyruvate-ferredoxin-oxidoreductase	gnl|CDD|237279	PRK13030, PRK13030, indolepyruvate ferredoxin oxidoreductase family protein.	0
CP020651.1|AWP86525.1|4536210_4537134_-|ribosomal-protein-L11-methyltransferase	gnl|CDD|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	9.01589e-110
CP020651.1|AWP87328.1|4534104_4535046_-|carbohydrate-kinase-family-protein	gnl|CDD|238917	cd01942, ribokinase_group_A, Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.	8.05228e-106
CP020651.1|AWP86523.1|4533427_4533931_-|lipoprotein	gnl|CDD|225675	COG3133, SlyB, Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane].	3.3638e-32
CP020651.1|AWP86519.1|4530459_4531587_-|membrane-bound-O-acyltransferase	gnl|CDD|274974	TIGR04091, hypothetical_protein, D-alanyl-lipoteichoic acid biosynthesis protein DltB. Members of this protein family are DltB, part of a four-gene operon for D-alanyl-lipoteichoic acid biosynthesis that is present in the vast majority of low-GC Gram-positive organisms. This protein may be involved in transport of D-alanine across the plasma membrane. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	6.72878e-50
CP020651.1|AWP86516.1|4526171_4527374_+|ribonucleotide-diphosphate-reductase-subunit-beta	gnl|CDD|235968	PRK07209, PRK07209, ribonucleotide-diphosphate reductase subunit beta; Validated.	0
CP020651.1|AWP86521.1|4531716_4532844_-|teichoic-acid-biosynthesis-protein	gnl|CDD|368189	pfam04914, DltD, DltD protein. DltD is and integral membrane protein involved in the biosynthesis of D-alanyl-lipoteichoic acid. This is important in controlling the net ionic charge in lipoteichoic acid (LTA). This family is found in bacteria of the Bacillus/Clostridium group. DltD binds Dcp and ligates it with D-alanine. DltD does not ligate acyl carrier protein (ACP) with D-alanine. It also has thioesterase activity for mischarged D-alanyl-acyl carrier protein (ACP). DltD is thought to be responsible for discriminating between Dcp involved in the D-alanylation of LTA, and ACP involved in fatty acid biosynthesis.	1.09917e-76
CP020651.1|AWP87327.1|4527691_4528264_+|histone	gnl|CDD|237855	PRK14900, valS, valyl-tRNA synthetase; Provisional.	9.48222e-16
CP020651.1|AWP86524.1|4535057_4536185_-|hypothetical-protein	gnl|CDD|378759	pfam11906, DUF3426, Protein of unknown function (DUF3426). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 262 to 463 amino acids in length.	1.69179e-42
CP020651.1|AWP86522.1|4532869_4533109_-|acyl-carrier-protein	gnl|CDD|223314	COG0236, AcpP, Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	3.22825e-07
CP020651.1|AWP86529.1|4539560_4540109_-|thioredoxin	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	8.20462e-37
CP020651.1|AWP86526.1|4537152_4538499_-|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	gnl|CDD|236307	PRK08591, PRK08591, acetyl-CoA carboxylase biotin carboxylase subunit; Validated.	0
CP020651.1|AWP86530.1|4540191_4541562_+|UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl--meso-diaminopimelate-ligase	gnl|CDD|130153	TIGR01081, mpl, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase. Alternate name: murein tripeptide ligase [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0

Protein sequences

>CP020651.1|AWP86522.1|4532869_4533109_-|acyl-carrier-protein
MHTEQELHTRIADIVESIILKKVTPDTALISSGLVDSLAAVDITLAVESEYGCSIPAPEIAEHLQSVRTLAGYVAANSQ
>CP020651.1|AWP86521.1|4531716_4532844_-|teichoic-acid-biosynthesis-protein
MASAVALSLGLYWGADGALSALVHPHSSVASVRDNYLPNLGPDWGTQNVNLNRLGNALADGTLVVLGSSELSSHDLRFVPYRFFPQELKVPTLAYGHAMFQSYGIVSVLEAVADSLTPNTRLVIMVSPAWFASGGQLPRSAFAEHVTGPVWDRLWDKPATREQMQDWIADNANWGLLWLIANGQVAELKDKIALWWNSRGERAPDRPRSPLAVPAHKYVSWPAAARLDAGRWHDLLGQARGIEAELGGHNPYDVRDDYYRQYLAPLNSPARNEFPEMPPMTRPELGDLARVMALLQQRKVRAYFVIQPFNPKLILDVERFDPVADAIKGMCARYGMGCLDMYSVPFQPGMVRDDMHLAELGWAIADQGIAEFFSR
>CP020651.1|AWP86520.1|4531594_4531720_-|hypothetical-protein
MKRFFWHLCLYLGLILVFVLQAQPTTGSGGPIKVEFQYQQF
>CP020651.1|AWP86519.1|4530459_4531587_-|membrane-bound-O-acyltransferase
MELFGSFAFFGGALFGGLGLLLYRALGLPWRLGYRHLIGALCLAVWLAVFWTRPYQPLGLLAVASAALWAMRRGHLPTWAAVLLTMAPLLLLKCGITTMTGMLGLSFATFRAVDVLLFAPRNERISPLDYCIYLFFPLTLLAGPMYRWRNFQADLKRGYEGVTLETWLAGLELLIFGVIQKFGVAEAIWRYGLNTLDAHDYSLTGVALNASLYSFYLFFDFAGYSSMAIGVGMLFGFTLPVNFRNPLASANPQDFWRRWHISLSEWLRDVVFMPIYKALSKTAFFGRHRLAAQNIGILATLLAMGVWNGLALHYVVSGLMFGAYSVGHNLLVQHARTRPALQAFLARRPVQWAGRALTLILAALALYVFSGRSPI
>CP020651.1|AWP86518.1|4528985_4530449_-|D-alanine--poly(phosphoribitol)-ligase
MRGMYFDLRSFEFVSDARGGQADAVVGSDRVLTWQALREEACQWAARARAHGIGPDVPVVIHGHKEAAFFVAMAGALLAGAPFVPVDTIYPPERVRRIVEIVRAAAVYDTQADVFRPGAAEPAALAERGLAYVMFTSGSTGDPKGVQIGRESVALLGDWLRDGLALGEAPVFMNQAPFSFDLSMYEVFGTLAAGGTCVLNAREQIAAPQQWLARLAGSGVTVWVSTPSFAHQQLANRDFSPQQLRALRTFLFCGEPLPVALARKLRQRFPEAAILNTYGPTEATVATTALVVDDAVLAEHDPLPVGYAKPASLLYVADDEICIVGDHVMRGYLNRPDLNQAKLFVHHDGRRGFRTGDLGRMREDGLLFCRGRMDDQIKLNGYRIELAEIDAALHALPGVAGGACAVLRRPDGTAVRVIGFVAQRTVEQASFQLPAALQQWKAQLTGRLPSYMVPSELVACPDLPVSNNHKIDRKKLLEIYAAIPAAA
>CP020651.1|AWP86517.1|4528402_4528978_+|YggT-family-protein
MATALMLGDIIRFLLEITFTLFGAALILRAWIHAVRLHPFNPLARAIYQGTNWLVLPLRRVIPATGSIDWTSLIAAWVAALIYLILVWLSAVGALPPASALPSAMGSALLMVLKWTLNLMVWMTLIQAVLSWVNPLSPLMPLLQTLTAPLLDPIRRILPRTAIDFSPLVLLIGAQILLMMVARLAYGIFGV
>CP020651.1|AWP87327.1|4527691_4528264_+|histone
MATAKKAAKKAVKKPAAKKAAAKKATPAKKAAVKKVAVKKVAAKKPAVKKVAAKKPAAKKVAKKAVAKKAVAKKPAAKKVAKKAVAKKAVAKKAVAKKAVAKKAVAKKAVAKKAVAKKAPAKKAAAKKAPAKKAAAARKPAAKKPAAKKPAAKKAAPKKPATPPSTAAAPGAKTALNPAASWPFPTGGRP
>CP020651.1|AWP86516.1|4526171_4527374_+|ribonucleotide-diphosphate-reductase-subunit-beta
MLNWEEENIATKPATSPAPAPAGGREAAPAVRAATGVFGDAALPTPTAPQHAASLGASDATAGRVKVADKRIINGETDVNQLVPFKYKWAWEKYLATCANHWMPQEINMSRDIALWKNPNGLTEDERRIVKRNLGFFVTADSLAANNIVLGTYRHITAPECRQFLLRQAFEEAIHTHAYQYIVESLDLDEAEIFNAYNEVPSIRAKDEFLIPFIDAIADPNFHTGTPEADQKLLKSLIVFACLMEGLFFYVGFTQILALGRQNKMTGAAEQYMYILRDESMHCNFGIDLINTIKLENPHLWTPEFREEIRELFRKAVELEYAYAEDTMPRGVLGLNAPMFKSYLRFIANRRCQQIGIEPLFPQEENPFPWMAEMIDLKKERNFFETRVIEYQTGGTLSWE
>CP020651.1|AWP86515.1|4523222_4526150_+|ribonucleoside-diphosphate-reductase-subunit-alpha
MQTTIASVTRPTAVPPAQSETSTDPNSGQWASYNIIRRNGSVVGFEPSKIAIAMTKAFLAVNGGQGAASARVRELVEQLTAQAVSALVRNRPAGGTFHIEDVQDQVELALMRSGEHDVARAYVLYRERRAQERAAAAEVLEKSSPAAAQEPTLSVVDNGVRRPLDLAALRATIEAAGEGLTQYTDTEAILKETVKNLYDGVPVDEVFKSAILAARALVEKDPAYSQVTARLLLHTIRKEVLGEEVSQADMATRYAEYFPAFIQRGIEGGLLDAKLAEYDLERVAKALDGRRDLQFGYLGLQTLYDRYFLHVRGTRIELPQVFFMRVAMGLALREADREARAIEFYEILSSFDFMSSTPTLFNSGTLHSQLSSCYLTTVSDDLEGIYDAIKENALLAKYAGGLGNDWTPVRALRSHIKGTNGESQGVVPFLKVVNDTAVAVNQGGKRKGAVCTYLETWHLDIEEFLELRKNTGDERRRTHDMNTANWIPDLFMKRVMENGEWTLFSPSDCPDLHDKYGKAFEQAYAGYEAKVASGELKLFKKMPAVSLWRKMLSMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNATEIAVCNLGSVNLVAHMKPSANGGYELDHDKLKRTIGVAMRMLDNVIDINYYAVDKARNSNERHRPVGMGIMGFQDCLHVMRVPYASQDAIDFADRSMEAVCYHAYWASSELAQERGRYQSYEGSLWSRGILPQDTLAMLREERGGNVDVDDSSSLDWDTLRSRIKEHGMRNSNCIAIAPTATISNIIGVSACIEPTFQNLYVKSNLSGEFTVVNDYLVRDLKKLGLWDEVMVADLKYFDGSLSRIDRVPSELRKLYATAFEVEPSWLVECASRRQKWIDQAQSLNIYMSGASGKKLDDTYKLAWQRGLKTTYYLRTLGATSAEKSTGRGGELNAVSAGDHGAGSAVSAAPVLPEPEIVGAVCTMRPGDPGFEECEACQ
>CP020651.1|AWP86514.1|4519410_4522917_+|pyruvate-ferredoxin-oxidoreductase
MDGTPAVDPHIDLDYQLGDNLTRTSGRVFLTGTQALVRMMLTQRRLDRDRGLNTAGFVSGYRGSPLGGFDMAMWKAGQALADNQVSFLPGINEDMAATAVMGTQQAGVRADRKVDGVFAMWYGKGPGVDRAGDALHHGNAAGASRHGGVLVVVGDDHTAVSSSIPHASEASLIGWHMPIVHPASIDEYETFALWGWALSRYSGAWVAFKAVSETVECGQSFVLEPPAAYEMPDDPELPAEQLEYTARDFLSPAVELRMHRRLRAVRAFARRHSLDRLVCAAPRATLGIVTVGKAHLDTMEALHRLGLDTVGAQAPVRIYKPGLTWPLDGPRLIEFAQGLRHILVIEEKGAVVESQIKDLLFNLPQRPSVAGKTGLDGAELIPAAGQLRPSLLAAPLAAWLRRAGHMPGGAAPAAFACPAPLSNDADGMRRRPYFCSGCPHSTSTKVPEGSQALAGVGCHYMAAWMDRDTGGLTQMGGEGADWIGLSPYIEMPHVFQNMGEGTYYHSGYLAIRQAVAARANITYKILFNDAVAMTGGQPVDGPISVPQICQQLRGENVARIVVTTDEPEKYRGVALGAGIDVHHRRDLDAVQRELRATPGVTVLIHDQTCAAEKRRRRKKNQFPDPPRRLLINSAVCEGCGDCGVQSNCLSVVPLETPYGRKRAIDQSSCNKDYSCVEGFCPSFVSVMGGKPRKSAAPAADHERLRARIARLPEPRPAPLEAPYRLLVAGMGGTGVITIGAIVSMAAHLQGLSAAVLDLTGLAQKGGTVVSHIRLAPSGTANGPVRLDWQQADAAILCDPVAAVAPDSLGALRRDHTRTTVNTYVAPVSDFTRNPDAPLRADALLAKIRHAAGEHVAALDAHAAAQALFGDSILSNMFMLGHAWQRGDVPLALAALARAIELNGVAVAANRAAFDAGRLAAHEPQSMAQALRPAAQVVQLHIPESFERAVERRVADLTAYQSAAYAQAYRDLVEQVAARERELAPAARAPRLAMAVARSLFKLMAYKDEYEVARLYTDDAFRAQLDSQFEGDYSLRLHLAPPLLARKDPRTGAPRKITLGPRTLTLMKALARLKGLRGTWFDPFGHTAERRMERALVAEYRATVIQLLAGLSVDRLAQAATIAALAETVRGYGHVKQASVRKYRDELERQLRRYQEPTGSPDVSLRQTA
>CP020651.1|AWP86523.1|4533427_4533931_-|lipoprotein
MNYMHSPSVVAGRARRLLAVAAVAGSVAVLAGCANPSASSGVYTYGQAQREQIVRTGTVTGVRPITIQNDKSSGVGMVAGGALGGVAGNAVGGGTGRTIATVGGVILGALAGNAIENRAGKSSGYEITVRLDNGETRVVAQEADVPISVGQRVQVISGAGPTRVTPY
>CP020651.1|AWP87328.1|4534104_4535046_-|carbohydrate-kinase-family-protein
MTAPVLVCGSMAFDTIAVFEGRFKEHILAERIQSLSVSFLVPAMRKEYGGCAGNIAYNLKLLGGQPVPVATVGEDAGEYLARLSGLGIDVSRIQVVPGTFTAQCFITTDLEDNQIAAFHPGAMEFSSGNDLSDAQAAWAIIAPDSKAGMFAHAERLHARGIPFIFDLGQAMPLFDGADLERMLKLAQALTVNDYEAGVVEQRTGRSLAEIASGLRAAVVTRGAHGATVMAGGQTIEVAPVQAQAVVDPTGCGDAHRAGLLYGLTSGWGWADSCRLGNLMGAIKIASRGPQNHAPSRSEIDALMRANYGIGLPD
>CP020651.1|AWP86524.1|4535057_4536185_-|hypothetical-protein
MALTTRCPQCGAAFRVVADQLRVRNGLVRCGECATVFDGRACLVPAPDAGAPRAAAPPVPSAPPVPSAPPSDPPFDPPYAHRAASEPAAPATQAPPAVLRGRADMQRGDAPPVDEDEPDAMADGAPEDEADWDAAPRLESAEAGWRPILPRDPAHDDREPAFRIGRTATACAAADAEDAVQVPGEVRTRYSNAVDSGRTPPEFLDDDRIQARQLVRRLWAYACVLGVLALAAQLVYVYRGAIAGAAPALRPVLEQACVPLQCSVGHARRIERISITSSSLRPAAGAAQGDDARTRLTLNVVLRNRYDRPQEWPALVLDLTDISDTVVARKIILPQDYLPSQAGPAFAAGSEINLAIPVEVAGLQVNGYQLDKFFP
>CP020651.1|AWP86525.1|4536210_4537134_-|ribosomal-protein-L11-methyltransferase
MRELVLNCREAQADALSDALLEAGVLSVSVEDADLGTEAERPLFGEPGTEPQVQAWERNCVVALLPDGADPAQILEQAIAAAGLDPALAHGWSLREVPDADWVRLTQSQFGPIPISERLWIVPSWHRDDPAVPGLVPDAARDAIHIELDPGLAFGTGSHPTTHLCLAWLEAELPAGARLLDYGCGSGILAIAARKLGAGETVAVDIDPQAVQSTVDNAEVNQVRLQAMLPDALPAGEFQVVVANILSNPLKVLAPMLAGRVAPGGHLVLSGVLERQADEVAAAYAPWLTMSVWRERDGWVCLHGVKA
>CP020651.1|AWP86526.1|4537152_4538499_-|acetyl-CoA-carboxylase-biotin-carboxylase-subunit
MFEKILIANRGEIALRIQRACRELGIKTVVVHSEADRTAKYVRLADESVCIGPAPSRESYLNMPALISAAEVTDAEAIHPGYGFLAENADFAERVEKSGFVFIGPRPETIRQMGDKVSAKRAMIEAGVPVVPGSEGALPDDPQEILRIAREVGYPVIIKASGGGGGRGMRVVYTEAALLNAVNMTRSEAGAAFNNPEVYLEKFLENPRHVEIQVLADGGRNAVWLGERDCSMQRRHQKVIEEAPAPGIPRRLIERIGDRCADACRKMGYRGAGTFEFLYENGEFYFIEMNTRIQVEHPVTELITGVDVVQQQILIAAGEKFTLRQRDIQFKGHALECRINAEDPFRFVPSPGRITNWHVPGGPGVRIDSHAFNGYFVPPNYDSMIAKVITYGDTREQALARMRIALSEMVVEGISTNIPLHRELLQDARFIEGGTSIHYLEHKLAQRP
>CP020651.1|AWP86527.1|4538508_4538958_-|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit
MDLRKLKTLIDLVAESGIAELEITEGEGKVRIVKFSQALQPVAYHMPEAVAPAAAPAAAAVPAAEAAPAAPQGHVVKAPMVGTFYRAPNPGAAPFVDVGQSVKEGDPLCIIEAMKLLNEIEADKAGVIKEILVENGEPVEYGQPLFIIG
>CP020651.1|AWP86528.1|4539047_4539482_-|type-II-3-dehydroquinate-dehydratase
MAQRILVLHGPNLNLLGTREPHIYGSLTLAQIDQGLAALAGQLGVALTSWQSNHEGALVERIQAAAADGTDFIIINAAAYTHTSVAIRDALAAVAIPFIEVHLSNLYKRDSFRQHSYLSDLAIGLITGLGADGYEAALRYAARH
>CP020651.1|AWP86529.1|4539560_4540109_-|thioredoxin
MNRRLFLYAGVAAAAAASGGYFLAERRNARPAPSAAAPAEGAGDPLAQLRQLALPDLQGTPRKLADWGGQPLVVNFWATWCAPCVKEMPELDALQKKYPQVRFVGIGVDTADNMRKFVEKIPVSYPLLVMGAGAIDTLRSLGNPSGGLPFTLLLSADGSMKRKILGQIVYDDLDRSVAGLSA
>CP020651.1|AWP86530.1|4540191_4541562_+|UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl--meso-diaminopimelate-ligase
MHLHILGICGTFMGGLALIARSAGHKVTGCDAGVYPPMSTQLAEQGIELIEGFGADQLALAPDLFVIGNVVSRGNPLMEAILDSGARYISGPQWLGEHILPGAHVLAVAGTHGKTTTSSMLAWILQCAQRQPNFLIGGVAPDLQVSARYAPGARPFVIEADEYDTAFFDKRSKFVHYRPRTAILNNLEYDHADIFPDLAAIETQFHHLVRTVPSNGQLVLPTDAPALERVLERGCWTPVARFGPGGQWQAGPADEQGAFEVSVDGRDAGTVRWTLGGEHNRRNALAALAAARHAGVAPAEGIEALSRFGGVKRRMELRGTVNGIRVYDDFAHHPTAIATTIEGLRRQVGAARILAVLEPRSNTMKLGTMAARLPEALAGADLVFCFGDHAGKHALGWDPARVLAPLGERAAGYDDLPALVRAVAAAARPGDHVLVMSNGGFGGVHGKLLDALAQPR
>CP020651.1|AWP86531.1|4541572_4542166_+|esterase
MPILYLHGFRSSPDSFKARLLAQAMHQRGLAGQWQCPQLPASPRQAAELALALAREQLAGQQDPRRLTVIGSSLGGYYATWLAERLGCQAVLLNPAVQAARDLATQVGEHRMYHSDAPFHFLPEYVEELRALYADPLTHPERYFLVAATGDEVLDWREMRDRYPGCRQRIVQGGDHGLSDFPRWMPEVLEFALGSPH

Crispr_ID: CP020651_10

• CRISPR_ID: CP020651_10
• CRISPR_location: 4676331-4676414
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP020651_10

Consensus_repeat	Method
GGTGCCTGTCCCCGCGGGGACAG	CRISPRCasFinder

spacers of CP020651_10

>10.1|4676354|38|CP020651|CRISPRCasFinder
ATACCGTCTTGGCCGTCAAGCGTTCTGGCGTATGACGG

CRISPR arrays and Neighbor proteins around CP020651_10

CRISPR arrays

The CRISPR arrays of CP020651_10

>merge|CP020651|10|4676331-4676414|CRISPRCasFinder
GGTGCCTGTCCCCGCGGGGACAGATACCGTCTTGGCCGTCAAGCGTTCTGGCGTATGACGGGGTGCCTGTCCCCGCGGGGACAG

>CP020651|10|10|4676331-4676414|CRISPRCasFinder
GGTGCCTGTCCCCGCGGGGACAG	ATACCGTCTTGGCCGTCAAGCGTTCTGGCGTATGACGG
GGTGCCTGTCCCCGCGGGGACAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP020651.1|AWP86652.1|4675080_4675824_+|phospholipid-binding-protein	unknown	unknown	gnl|CDD|182907
CP020651.1|AWP86661.1|4683722_4685675_-|penicillin-binding-protein-2	unknown	unknown	gnl|CDD|274573
CP020651.1|AWP87330.1|4669634_4670387_-|cytochrome-c	unknown	unknown	gnl|CDD|225418
CP020651.1|AWP86654.1|4676468_4677257_-|methionine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|224381
CP020651.1|AWP86651.1|4674481_4675084_+|phosphoheptose-isomerase	unknown	unknown	gnl|CDD|237567
CP020651.1|AWP86663.1|4686238_4687123_-|rod-shape-determining-protein-MreC	unknown	unknown	gnl|CDD|237560
CP020651.1|AWP86646.1|4670558_4671431_+|RNase-adaptor-protein-RapZ	unknown	unknown	gnl|CDD|235450
CP020651.1|AWP86653.1|4675820_4676312_+|thioredoxin	unknown	unknown	gnl|CDD|239264
CP020651.1|AWP86645.1|4668337_4669624_-|cytochrome-c	unknown	unknown	gnl|CDD|365823
CP020651.1|AWP86656.1|4678420_4679167_+|pyrimidine-5'-nucleotidase	unknown	unknown	gnl|CDD|319791
CP020651.1|AWP86648.1|4672374_4672947_-|cysteine-methyltransferase	unknown	unknown	gnl|CDD|223427
CP020651.1|AWP86650.1|4673948_4674482_+|YraN-family-protein	unknown	unknown	gnl|CDD|173148
CP020651.1|AWP86657.1|4679216_4679792_+|nucleoid-occlusion-factor-SlmA	unknown	unknown	gnl|CDD|181894
CP020651.1|AWP86660.1|4682589_4683726_-|rod-shape-determining-protein-RodA	unknown	unknown	gnl|CDD|274033
CP020651.1|AWP86658.1|4680004_4681498_+|hypothetical-protein	unknown	unknown	gnl|CDD|279307
CP020651.1|AWP86647.1|4671427_4672378_+|lipoprotein	unknown	unknown	gnl|CDD|223868
CP020651.1|AWP86649.1|4672943_4673882_-|rRNA-(cytidine-2'-O-)-methyltransferase	unknown	unknown	gnl|CDD|223390
CP020651.1|AWP86659.1|4681508_4682564_+|lactate-dehydrogenase	unknown	unknown	gnl|CDD|376860
CP020651.1|AWP86662.1|4685688_4686252_-|rod-shape-determining-protein-MreD	unknown	unknown	gnl|CDD|274574
CP020651.1|AWP86655.1|4677518_4678421_+|acetylglutamate-kinase	unknown	unknown	gnl|CDD|234869

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP020651.1|AWP86652.1|4675080_4675824_+|phospholipid-binding-protein	gnl|CDD|182907	PRK11023, PRK11023, divisome-associated lipoprotein YraP.	1.20064e-42
CP020651.1|AWP86661.1|4683722_4685675_-|penicillin-binding-protein-2	gnl|CDD|274573	TIGR03423, pbp2_mrdA, penicillin-binding protein 2. Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
CP020651.1|AWP87330.1|4669634_4670387_-|cytochrome-c	gnl|CDD|225418	COG2863, COG2863, Cytochrome c553 [Energy production and conversion].	1.39738e-12
CP020651.1|AWP86654.1|4676468_4677257_-|methionine-ABC-transporter-substrate-binding-protein	gnl|CDD|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	1.17353e-136
CP020651.1|AWP86651.1|4674481_4675084_+|phosphoheptose-isomerase	gnl|CDD|237567	PRK13936, PRK13936, phosphoheptose isomerase; Provisional.	1.25469e-125
CP020651.1|AWP86663.1|4686238_4687123_-|rod-shape-determining-protein-MreC	gnl|CDD|237560	PRK13922, PRK13922, rod shape-determining protein MreC; Provisional.	9.0892e-90
CP020651.1|AWP86646.1|4670558_4671431_+|RNase-adaptor-protein-RapZ	gnl|CDD|235450	PRK05416, PRK05416, RNase adapter RapZ.	1.18739e-149
CP020651.1|AWP86653.1|4675820_4676312_+|thioredoxin	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.58284e-41
CP020651.1|AWP86645.1|4668337_4669624_-|cytochrome-c	gnl|CDD|365823	pfam00034, Cytochrom_C, Cytochrome c. The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family.	4.18466e-10
CP020651.1|AWP86656.1|4678420_4679167_+|pyrimidine-5'-nucleotidase	gnl|CDD|319791	cd02604, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to Saccharomyces cerevisiae Phm8p and Sdt1p. This family includes Saccharomyces cerevisiae Phm8p (phosphate metabolism protein 8) and Sdt1p (Suppressor of disruption of TFIIS). Phm8p participates in the ribose salvage pathway, it catalyzes the dephosphorylation of nucleotide monophosphates to nucleosides, its preferred substrates are nucleotide monophosphates AMP, GMP, CMP, and UMP. Phm8p is also a lysophosphatidic acid phosphatase, dephosphorylating lysophosphatidic acids (LPAs) to monoacylglycerol in response to phosphate starvation. Sdt1p is a pyrimidine and pyridine-specific 5'-nucleotidase; it is an NMN/NaMN 5'-nucleotidases involved in the production of nicotinamide riboside and nicotinic acid riboside, and is a pyrimidine 5'-nucleotidase with high specificity for UMP and CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.14842e-46
CP020651.1|AWP86648.1|4672374_4672947_-|cysteine-methyltransferase	gnl|CDD|223427	COG0350, Ada, Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair].	7.98182e-54
CP020651.1|AWP86650.1|4673948_4674482_+|YraN-family-protein	gnl|CDD|173148	PRK14685, PRK14685, hypothetical protein; Provisional.	1.2057e-90
CP020651.1|AWP86657.1|4679216_4679792_+|nucleoid-occlusion-factor-SlmA	gnl|CDD|181894	PRK09480, slmA, division inhibitor protein; Provisional.	1.59741e-107
CP020651.1|AWP86660.1|4682589_4683726_-|rod-shape-determining-protein-RodA	gnl|CDD|274033	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA. This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	3.23854e-160
CP020651.1|AWP86658.1|4680004_4681498_+|hypothetical-protein	gnl|CDD|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	2.68833e-115
CP020651.1|AWP86647.1|4671427_4672378_+|lipoprotein	gnl|CDD|223868	COG0797, RlpA, Lipoproteins [Cell envelope biogenesis, outer membrane].	3.79567e-55
CP020651.1|AWP86649.1|4672943_4673882_-|rRNA-(cytidine-2'-O-)-methyltransferase	gnl|CDD|223390	COG0313, COG0313, Predicted methyltransferases [General function prediction only].	9.54075e-109
CP020651.1|AWP86659.1|4681508_4682564_+|lactate-dehydrogenase	gnl|CDD|376860	pfam02615, Ldh_2, Malate/L-lactate dehydrogenase. This family consists of bacterial and archaeal Malate/L-lactate dehydrogenase. L-lactate dehydrogenase, EC:1.1.1.27, catalyzes the reaction (S)-lactate + NAD(+) <=> pyruvate + NADH. Malate dehydrogenase, EC:1.1.1.37 and EC:1.1.1.82, catalyzes the reactions: (S)-malate + NAD(+) <=> oxaloacetate + NADH, and (S)-malate + NADP(+) <=> oxaloacetate + NADPH respectively.	1.11307e-125
CP020651.1|AWP86662.1|4685688_4686252_-|rod-shape-determining-protein-MreD	gnl|CDD|274574	TIGR03426, shape_MreD, rod shape-determining protein MreD. Members of this protein family are the MreD protein of bacterial cell shape determination. Most rod-shaped bacteria depend on MreB and RodA to achieve either a rod shape or some other non-spherical morphology such as coil or stalk formation. MreD is encoded in an operon with MreB, and often with RodA and PBP-2 as well. It is highly hydrophobic (therefore somewhat low-complexity) and highly divergent, and therefore sometimes tricky to discover by homology, but this model finds most examples. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	7.62373e-19
CP020651.1|AWP86655.1|4677518_4678421_+|acetylglutamate-kinase	gnl|CDD|234869	PRK00942, PRK00942, acetylglutamate kinase; Provisional.	1.71108e-158

Protein sequences

>CP020651.1|AWP86653.1|4675820_4676312_+|thioredoxin
MKKIALVLIIAVAAGIGGWFMWRPAQTAPDVAFTTLEGQKITMQDLRGKVVLVKFWATSCVTCVKQMPDNIANYNQYHPQGYETIAVAMNYDPPNYVLNFAQTRKLPFPVALDTSGELAQAFGNVRLTPTAFLIDKQGQIIKRYLGEYDKAEFQATVQKALAG
>CP020651.1|AWP86652.1|4675080_4675824_+|phospholipid-binding-protein
MMPDAKTAARPLLLAAALSAAALTLSACAPLVIGGAAATTAVVVTDRRTSGVQLEDQNIAFKAESQIAQKLGNTARVNAMVYGGHVLLTGDAPTEEAKAQATAIAQSIENVKAVTNQLTVGPAADFSTRSNDTWLTSKVKTALINTKYVPSGTISVTTSRGVVYLMGKVTQAEGDYAANAAAGVGGVARVVKLFETISREEAIRLSGSGTKSGEGSSDGTAAQKAPIESGAAPAGSGSNGVEAIPIK
>CP020651.1|AWP86651.1|4674481_4675084_+|phosphoheptose-isomerase
MRAMDMTSRMTSHFRDAMALCEQSADALAAPLAAAVDLLFAALANNGRILACGNGGSAADAQHFIAELVGRFERERLPLAGIALNTDTSIMTAVGNDYGFDEIFERQVHALGQPGDVLVAISTSGNSPNVVRAMETAREREMHVIALTGKGGGVMGELITPHDVHLCVPHDRTMRIQEVHIILLHALCDGIDALLLGDTE
>CP020651.1|AWP86650.1|4673948_4674482_+|YraN-family-protein
MTDTATRLAFARAAQAQRRLHRRPPASPRARPGARDGGSPTQRRGQAYESAALRWLARQGLRPLARNLRCRAGEIDLAMRDGEVLVLVEVRVRAHAGYGGAAASIGASKQGRLARAAALLLPVLLRRHWPGAPPPVRFDVVAFEAGRPHWLRGAFWLAEHAPAQGRRGQDAQGWRVR
>CP020651.1|AWP86649.1|4672943_4673882_-|rRNA-(cytidine-2'-O-)-methyltransferase
MNQDVLSPAPGDAWSRVADRVAAQHWPAATLYVIATPIGNLGDLGLRAWQALVRADVIAAEDTRASRTLLDAWGVSTPLMAAHRHNEASAAQAICERLAQGQRVALVSDAGAPAVSDPGARIVRAVREAGYAVVPVPGPSAVIAALMGSGATSDENPAFAFAGFPPAKAVARQRWLRQWCALPAPVVMFESPHRLAATLADLREAGGPARLLTVARELTKRFEEIATMPLGEAADWLAADAHRGQGEFVLIVHQAPGAQDDEADPADPRTDALLDALLESLSVRDAARVAAKVTGLARDVLYARALARKEQP
>CP020651.1|AWP86648.1|4672374_4672947_-|cysteine-methyltransferase
MNPPSEQATDILYCDTDTPLGPMRLAARGQALCGAWFVDQRDCPAAAGWTPDAAHPALRQAAAELEQWFAGRRRAFEVDMQPEGTPFQRQVWQALLELPFGATISYGELARRVGRPKAARAVAGAVGRNPISILIPCHRIIGHDTSLTGFGGGLPRKQALLAHEGHRYLSRAARARRVSTTQMELPFGAA
>CP020651.1|AWP86647.1|4671427_4672378_+|lipoprotein
MIRSRPLALLSTLLLALAIAGCSTPGKKRGGYYKDDGPDANPPSNLDNVPDATPRLEPLASGPNRPYVVFGKRYVPDTSERPFRQQGLASWYGKKFHGNSTSNGESYDMYAMTAAHPTMPIPSYARVTSKINGRTVIVRVNDRGPFHSDRIMDLSYVAAHKLGIIGPGSGPVTVERILPAEILAMNGGAAAPRPGPASATGPLPVAAPSAAAAVELHPATQLASNAPTPPRPATGAGSGIYLQLGAFSQPANAESLVSRINGQLDPASGIPPAVVEQANNLYRVRIGPYATREAALGAVQPVADRTGILPSLSATP
>CP020651.1|AWP86646.1|4670558_4671431_+|RNase-adaptor-protein-RapZ
MLRVVLITGISGSGKSVALRLLEDAGFTCIDNLPVRFLAEFIANARDDAMERVAVAIDVRSPGELAELPDVITASRAMGTSLSVIFLDANTDTLVQRYSESRRRHPLTDRLARGGKTPSLAECIALERELMAPLRDQEHVIDTSDLTPGQLRAWIRDLIQADRPPLVLTFESFAYKRGVPSDADLMFDVRCLPNPYYDRTLRPLTGRDEPVATWLGGFDIVTQMIDDIAAFIRRWLPQYTQDTRNYLTVAIGCTGGQHRSVYVVEQLARRFSDHDPLLVRHRTQLPDDPA
>CP020651.1|AWP87330.1|4669634_4670387_-|cytochrome-c
MLAFKSDLRIAMRAWRAACGVLAAAAGMLAMSQAVAQGEAALRPDTMAARVAACTACHGEQGRAGPDGYYPRLAGKPQDYLYHQLLNFRDARRQYPPMAHLLNGLPDAYLREMAAYFAGQDVPYPPPARVEASAALVERGRLLVREGDPARAIPSCASCHGASLAGVAPAIPGLLGLPRDYLVAQIGSWQNGLRRAAEPDCMAQVSLKLTPEDIGAVSAWLAGQPVGHPYTPQPAGSLTLPLECGSQAGH
>CP020651.1|AWP86645.1|4668337_4669624_-|cytochrome-c
MKIIKRVLVVAILALLAAVATLYWLGTRDHVPAGPQAAPATGSADELVEQGRYLARAGNCMACHTARGGQAYAGGTPIPTPFGTLYGPNITPDAETGIGGWSADDFWQALHNGKGPGGRLLYPAFPYTEYTRMTRADADALYAFLRTVEPVRQASRPHELASPYDQRLLLAAWRALYFEPGGPQADPGQSLQWNRGRYLTEGLGHCAACHTPRNSLGATRAAEALGGGMIDGLGWYAPPLTGQPGTGLGDWSAQDIAALLTTGIAPHSTVAGPMAEVVLGSTQYLSGDDALAIGTYLKSLPAAAPPPARRGAPSATVMELGGKLYGQHCAQCHQADGKGSFPAWPALAGNPSVIAAEPANVIRMVLDGGFAPATAANPRPHGMPPFAQALPDNDIAMLVSYVRNSWGNQAGAVTPLDVKRTRESGAGR
>CP020651.1|AWP86654.1|4676468_4677257_-|methionine-ABC-transporter-substrate-binding-protein
MRMNFVRSALLASAFLLAGGAAQAEKLVVGATQVPHAEILEVVKPALAKEGVELDIKVFTDYVQPNLQLADKQLDANFFQHQPYLDTFNKDRKTNLVSVGLVHVEPFGGYSKKIKSLAELKDGATIAIPNDPSNSGRALLLLQKQGLLKLKDPSNIVATPIDIAENPKKLKFRELEAAMLPRSLDDLDLALINTNYALEAGLVPTRDALFIEGADSPYANLVAARPDNKDAPAVKKLVNALHSEAVRKFIIEKYKGAVVPAF
>CP020651.1|AWP86655.1|4677518_4678421_+|acetylglutamate-kinase
MTDTPDPAAVLSPAVKAAVLSEALPYIRRFHGKTIVVKYGGNAMTEERLQRSFAHDVVLLKLVGLNPVVVHGGGPQIDDALRRIGKQGTFVQGMRVTDAETMEVVEWVLGGQVQQDIVMMINEVGGKAVGLTGKDGMLIQATKKLMVNKDDPSQPLDIGFVGDITRVEPAVVKALQDDQFIPVISPIGYGEDGTAYNINADVVAGKMAEVLGAEKLLMMTNTPGVLDKGGKLLRSLSAQTIDELFADGTISGGMLPKISSSLDAAKNGVNSVHIVDGRVPHCLLLEILTDQGVGTMISSH
>CP020651.1|AWP86656.1|4678420_4679167_+|pyrimidine-5'-nucleotidase
MQARRYLLRPAARLRRSRRIATAAPERLWLFDLDNTLHDTSHAIFPLIDRGMTEAVAETLAVDEATANRLRAEYWRRYGATVIGLVRHHGVDADAFLHRSHNFEVAPLVRAETALADKLRRLPGRKVLLTNAPLHYARAVLRHLGLLRQFDSIWAIEQMRMHGQFRPKPSDALLRYVLAREGVPAARAVLIEDTLDNLRSARRVGLRTVHVFHPGTPFARGHRQRPGYVDLRVNSVSDLLLRRRPLRG
>CP020651.1|AWP86657.1|4679216_4679792_+|nucleoid-occlusion-factor-SlmA
MASKPGERKTQILHTLAEMLEQPHAARITTSALAARMQVSEAALYRHFASKAQMFEGLIEFIETSIFTVVNQIAVSEPYGMGQARKTVAMLLAFAERNRGITRVLTGDALVTEDNRLQERINHINDRIEASLKQCLRVAVSDGALPADANIAAHASLLTHLVLGRWLRYAQSGWRVAPTTHLEEHLRLALG
>CP020651.1|AWP86658.1|4680004_4681498_+|hypothetical-protein
MTAPAAVPAPQSPPKVKIPIGLIAGIIAMVVVLLLPLPAELPPAGHRMLAILAFAVVVWITEAVSYEASAIMITTLMAFLLGTAPNVKNPDVLYGTSAAISMALTGFSNSALALVTGALFIAAAMTFTGLDKRIALVTLARVGTSTRRILLGAIAVTIVLSLVVPSATARSAAVVPIMLGVIAAFGVDKRSNIAAGIMIIVAQATSIWNVGIQTAAAQNLLTVGFMDKMLGERVAWSDWLIAGVPWSLLMSAVLIFVVLRLLPPESDAIAGGKEAVEASLRELGPMTSAQKRLMLVSIMLLLFWSTEGKLHKFDTTSTTYFGLVLLMLPRFGVMTWKDVQTRIPWGTVIVFGVGISLGTALLTTQAGQWLGAQVVAHTGLDHLGPLGIFAILSAFLILIHLGFASATALTSAMLPILIAVLQTLPGDFNRLGMTMLLGFVVSYGFILPINAPQNMVALGTETFTAKQFAKVGIVLTIVGYLLMLLMSVTYWRWLGWM
>CP020651.1|AWP86659.1|4681508_4682564_+|lactate-dehydrogenase
MKLSIAQAIAFGQRLLAAQGVPDDIARDVAEHLVESDRVGYTSHGLSILPNYRRVLAEGFVKADGRARLLNDRGAMLAFDGDNGFGQHVGKAVMQQAIERARQYGQCIVTLRRTHHLGRMGYYGEMAAEAGLILLAFTNVVNRPPTVAPYGGAQACLTTNPLCFAGPLPGGRPPFLVDMATSSIAVNKARVLAARGEPAPDGALIDAQGNPTNDPNALFADPPGALLPFGGHKGYAMGLVAELLAGVLSGGGTIQPEHPRNGVATNNMFAILLDPQVDFNADWRTQEVGAFIDYLHACPPQPGVDRVQYPGEYEAMNRARHAEAIEFEGAIWDSLAKLAQDLGAADALPRA
>CP020651.1|AWP86660.1|4682589_4683726_-|rod-shape-determining-protein-RodA
MKRLGLILLRVFTAFDWPLLLILILFTLLGLTVMHSAVGSTDWRFAEQSRNFLIAFAAMWAMALVPPNTLMKLALPFYVLGVILLLGVEFFGETSKGATRWLNLGVTRIQPSEMMKIAVPMMLAWYFQRHDGAVRIRDFFVAAAMLAAPFVLIVLQPDLGTALLVFGAGFFVIYFAGLSFKLLVPCLLAGIIAIGTLIYYEDQLCEPEVDWVVLHDYQKHRVCTLLNPSSDPLGKGFHTIQSMIAVGSGGLYGKGYMQGTQTHLDFIPERTTDFIFAVYAEEFGLYGGVALLVLYGLFMARGLAIASRASSQFGRLLAGAITMMMFIYVFVNVGMVTGILPVVGVPLPFMSYGGTALLTMGIACGILMSISRRRPAPA
>CP020651.1|AWP86661.1|4683722_4685675_-|penicillin-binding-protein-2
MFEFKKTGQQQKQRFRLRAWVGGLFALACFGVLAGRFWYLQVDRYEGFSERADRNRIAVVPIPPRRGEILDRNGEVLARNYRTYTLEVVPAQAGNLDQLFDRLARVVYISPSDQRRFKRRVGESSRYASLQLRNNLNDTEAAWFSAHSFEFPGVELRARWVREYPQGEAAAHVVGFIGRIAENDIEELDKAGQLGNYRGTDVIGKKGIEKTWEAALHGRTGLEEVEVTAGGRPMRTLRRIDPVPGSDIMLSIDLELQKLAEQAFEGRRGALVALDPDTGEVLAFVSQPSFDPNLFVDGIDVENWRRLNESPDHPLINRPLYGTYPIGSTYKPFVALAALELGKRRATDRMPDPGYFEFGGQKFRNAGGAAYGMTDMHRAIVVSSDTYFYSLGPEIGVNALHDFSKQFGFGQITGIDLEGEKAGVLPSTEWKRKAYKDRDRQRWYAGETISVAVGQGYNSFTLLQLAQATSTLANSGLYRRPHLVHAIRDSRSGSVNPTEIAPDYRIPLKQENVDVIKRAMADVVRAGTARRAFAGAPYQAAGKTGTAQVFSLRGGQYRASAIDERLRDHALFMGFAPVEQPRIAVALIVENAGWGASAAAPIARTLFDNWLGRADAPSVVRAGAKPVAAEPEAAALELGATDGPMQERRQ
>CP020651.1|AWP86662.1|4685688_4686252_-|rod-shape-determining-protein-MreD
MERTKVSVPARRKLGTPSNVEPERLARPAHGVFVWGTVLLVWLLSLLPWRQWPGSPDVLVLVIAFWCVHEPRRVGLLTAFVFGLLLDVHDAGLLGGHALSYTLTAYGAIALHRRLQRFDLWSQAMHMLPVFFLAQLVTQIILAWLAGKWPGWQWAVSVGLTVAIWPLAGWVLHMPQRRYDDVESSAV
>CP020651.1|AWP86663.1|4686238_4687123_-|rod-shape-determining-protein-MreC
MQRQATPPLFRRGPPAEVRLAVLVILALALLIVDSQLRVLEPVRRAVSVALYPFQRAVMAPRDLVQQVDEWINAASLIRSENEALQRQRIELAQVATHAAQLAAENAQLRRLLGVTDTVAQSAVVVEVLYEPPNAFHQRLVFNKGAKSGLAPGMPVIDEGGVVGQIVRVTPMTAEAALVTDERVSIPVQVLRNGLRLIAFGANTPGVIEVRYLAANADIKVGDTIVTSGVGGLFPAGLPVAKVASVERDTASGFARALGEPLAHPERYRHFLVLQVDVDQAESNRQEADVDGAD

Crispr_ID: CP020651_11

• CRISPR_ID: CP020651_11
• CRISPR_location: 4759352-4759432
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP020651_11

Consensus_repeat	Method
GTGCCTGTCCCCGCGGGGACAGGCACCT	CRISPRCasFinder

spacers of CP020651_11

>11.1|4759380|25|CP020651|CRISPRCasFinder
TGTGCCGGCCCTCCGCAACGCTCGG

CRISPR arrays and Neighbor proteins around CP020651_11

CRISPR arrays

The CRISPR arrays of CP020651_11

>merge|CP020651|11|4759352-4759432|CRISPRCasFinder
GTGCCTGTCCCCGCGGGGACAGGCACCTTGTGCCGGCCCTCCGCAACGCTCGGGTGCCTGTCCCCACGGGGACAGGCACCT

>CP020651|11|11|4759352-4759432|CRISPRCasFinder
GTGCCTGTCCCCGCGGGGACAGGCACCT	TGTGCCGGCCCTCCGCAACGCTCGG
GTGCCTGTCCCCACGGGGACAGGCACCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP020651.1|AWP86726.1|4753342_4754320_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
CP020651.1|AWP86733.1|4761563_4763666_-|primosomal-protein-N'	unknown	unknown	gnl|CDD|235514
CP020651.1|AWP86729.1|4756224_4757235_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226967
CP020651.1|AWP86732.1|4759451_4761521_-|ATP-dependent-DNA-helicase-Rep	unknown	unknown	gnl|CDD|130146
CP020651.1|AWP86734.1|4763972_4765049_-|uroporphyrinogen-decarboxylase	unknown	unknown	gnl|CDD|234644
CP020651.1|AWP86723.1|4750030_4750267_+|hypothetical-protein	unknown	unknown	unknown
CP020651.1|AWP86727.1|4754327_4755248_+|peptide-ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
CP020651.1|AWP87333.1|4765124_4766006_-|hypothetical-protein	unknown	unknown	gnl|CDD|185070
CP020651.1|AWP86740.1|4771195_4771666_-|ATP-synthase-subunit-B	unknown	unknown	gnl|CDD|180240
CP020651.1|AWP86739.1|4770643_4771183_-|ATP-synthase-subunit-delta	unknown	unknown	gnl|CDD|235593
CP020651.1|AWP86736.1|4766620_4768021_-|ATP-synthase-subunit-beta	unknown	unknown	gnl|CDD|236447
CP020651.1|AWP86724.1|4750563_4752192_+|transporter	unknown	unknown	gnl|CDD|173863
CP020651.1|AWP86722.1|4749042_4749903_+|NAD(P)H-hydrate-dehydratase	unknown	unknown	gnl|CDD|238576
CP020651.1|AWP86730.1|4757237_4758143_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|226040
CP020651.1|AWP86728.1|4755244_4756228_+|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|223521
CP020651.1|AWP86737.1|4768063_4768969_-|ATP-synthase-subunit-gamma	unknown	unknown	gnl|CDD|235535
CP020651.1|AWP86731.1|4758186_4759320_+|peptidase	unknown	unknown	gnl|CDD|349881
CP020651.1|AWP86725.1|4752240_4753284_+|succinylglutamate-desuccinylase	unknown	unknown	gnl|CDD|349481
CP020651.1|AWP86735.1|4766188_4766611_-|ATP-synthase-epsilon-chain	unknown	unknown	gnl|CDD|234796
CP020651.1|AWP86738.1|4769067_4770609_-|ATP-synthase-subunit-alpha	unknown	unknown	gnl|CDD|236448

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP020651.1|AWP86726.1|4753342_4754320_+|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	7.49002e-115
CP020651.1|AWP86733.1|4761563_4763666_-|primosomal-protein-N'	gnl|CDD|235514	PRK05580, PRK05580, primosome assembly protein PriA; Validated.	0
CP020651.1|AWP86729.1|4756224_4757235_+|ABC-transporter-ATP-binding-protein	gnl|CDD|226967	COG4608, AppF, ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism].	5.08932e-129
CP020651.1|AWP86732.1|4759451_4761521_-|ATP-dependent-DNA-helicase-Rep	gnl|CDD|130146	TIGR01074, ATP-dependent_DNA_helicase_Rep, ATP-dependent DNA helicase Rep. Designed to identify rep members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
CP020651.1|AWP86734.1|4763972_4765049_-|uroporphyrinogen-decarboxylase	gnl|CDD|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	0
CP020651.1|AWP86727.1|4754327_4755248_+|peptide-ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.17965e-94
CP020651.1|AWP87333.1|4765124_4766006_-|hypothetical-protein	gnl|CDD|185070	PRK15115, PRK15115, response regulator GlrR; Provisional.	3.28422e-05
CP020651.1|AWP86740.1|4771195_4771666_-|ATP-synthase-subunit-B	gnl|CDD|180240	PRK05759, PRK05759, F0F1 ATP synthase subunit B; Validated.	2.79837e-52
CP020651.1|AWP86739.1|4770643_4771183_-|ATP-synthase-subunit-delta	gnl|CDD|235593	PRK05758, PRK05758, F0F1 ATP synthase subunit delta; Validated.	1.16567e-65
CP020651.1|AWP86736.1|4766620_4768021_-|ATP-synthase-subunit-beta	gnl|CDD|236447	PRK09280, PRK09280, F0F1 ATP synthase subunit beta; Validated.	0
CP020651.1|AWP86724.1|4750563_4752192_+|transporter	gnl|CDD|173863	cd08498, PBP2_NikA_DppA_OppA_like_2, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
CP020651.1|AWP86722.1|4749042_4749903_+|NAD(P)H-hydrate-dehydratase	gnl|CDD|238576	cd01171, YXKO-related, B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily.	3.94937e-73
CP020651.1|AWP86730.1|4757237_4758143_+|alpha/beta-hydrolase	gnl|CDD|226040	COG3509, LpqC, Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism].	9.10797e-08
CP020651.1|AWP86728.1|4755244_4756228_+|methionine-ABC-transporter-ATP-binding-protein	gnl|CDD|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.69803e-169
CP020651.1|AWP86737.1|4768063_4768969_-|ATP-synthase-subunit-gamma	gnl|CDD|235535	PRK05621, PRK05621, F0F1 ATP synthase subunit gamma; Validated.	1.30561e-149
CP020651.1|AWP86731.1|4758186_4759320_+|peptidase	gnl|CDD|349881	cd03885, M20_CPDG2, M20 Peptidase Glutamate carboxypeptidase, a periplasmic enzyme. Peptidase M20 family, Glutamate carboxypeptidase (carboxypeptidase G; carboxypeptidase G1; carboxypeptidase G2; CPDG2; CPG2; Folate hydrolase G2; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase; E.C. 3.4.17.11) subfamily. CPDG2 is a periplasmic enzyme that is synthesized with a signal peptide. It is a dimeric zinc-dependent exopeptidase, with two domains, a catalytic domain, which provides the ligands for the two zinc ions in the active site, and a dimerization domain. CPDG2 cleaves the C-terminal glutamate moiety from a wide range of N-acyl groups, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl, and pteroyl groups to release benzoic acid, phenol, and aniline mustards. It is used clinically to treat methotrexate toxicity by hydrolyzing it to inactive and non-toxic metabolites. It is also proposed for use in antibody-directed enzyme prodrug therapy; for example, glutamate can be cleaved from glutamated benzoyl nitrogen mustards, producing nitrogen mustards with effective cytotoxicity against tumor cells.	3.60898e-158
CP020651.1|AWP86725.1|4752240_4753284_+|succinylglutamate-desuccinylase	gnl|CDD|349481	cd06910, M14_ASTE_ASPA-like, Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like; uncharacterized subgroup. A functionally uncharacterized subgroup of the Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA) subfamily which is part of the M14 family of metallocarboxypeptidases. ASTE catalyzes the fifth and last step in arginine catabolism by the arginine succinyltransferase pathway, and aspartoacylase (ASPA, also known as aminoacylase 2, and ACY-2; EC:3.5.1.15) cleaves N-acetyl L-aspartic acid (NAA) into aspartate and acetate. NAA is abundant in the brain, and hydrolysis of NAA by ASPA may help maintain white matter. ASPA is an NAA scavenger in other tissues. Mutations in the gene encoding ASPA cause Canavan disease (CD), a fatal progressive neurodegenerative disorder involving dysmyelination and spongiform degeneration of white matter in children. This enzyme binds zinc which is necessary for activity. Measurement of elevated NAA levels in urine is used in the diagnosis of CD.	1.24688e-79
CP020651.1|AWP86735.1|4766188_4766611_-|ATP-synthase-epsilon-chain	gnl|CDD|234796	PRK00571, atpC, F0F1 ATP synthase subunit epsilon; Validated.	1.40936e-54
CP020651.1|AWP86738.1|4769067_4770609_-|ATP-synthase-subunit-alpha	gnl|CDD|236448	PRK09281, PRK09281, F0F1 ATP synthase subunit alpha; Validated.	0

Protein sequences

>CP020651.1|AWP86731.1|4758186_4759320_+|peptidase
MTTTLPDTDQLVAGIQSWIQCESPSNSPAGVTAMAHLAAEYARAVGLAVEIRPLNAEVGPLVYATNRAAGDTRPGVLVLGHLDTVHPIGTLQDNPCRIDGDRLYGPGSYDMKAGIYLALSALRGLPSPHATALPIDFLLVPDEETGSHASREHIEHYAARAKYALVCEPARPNGGKCVTARKGTGMLRLNVKGRPAHAGMQHEKGRSAIREMAHQVLELESMTDYERGITVSVGTIAGGTVTNTVPALCRCVVDFRVPDMGAAEDVLRRMRNLCAVGPDMELDIDVELNRPPMVKTEAATALLQLAQDFAAQAGFALEDAPMTGGGSDANFTSAMGVPTLDGLGADGDGAHTLNEYILVSTLATRMRFWELLLKALH
>CP020651.1|AWP86730.1|4757237_4758143_+|alpha/beta-hydrolase
MKPADLTNADRIALELGHAGRNAIPYLDDDRNADRPFTLNTYRPYGYTPDRPVVVVQHGVLRNGADYRDFWIPAADRHKLLIVAPTFSDEIWPGVESYNNGRAFTAAGNPRHVDGWTYALVARVLANIRAAEIADCEQVYLFGHSAGGQFVHRLMSSQPHAPFHAVTAANPGWYTLPTFEHRFPEGLDGVGLTEDHLARLLAYPMTILAGDQDIATDDPNLPSEPAALRQGPHRYARARHYYEAGQRAAAQRGLPFGWQLQVVPGIGHDGQAMSQVCASLWFDGRMPDAAELARLAGSQSA
>CP020651.1|AWP86729.1|4756224_4757235_+|ABC-transporter-ATP-binding-protein
MTTSDLPVIELRDVHKRFEHRPDMAQRLLALTGKPLDRRTVHAVNGVSLSVRRGEVLGLVGESGCGKSTLGRVVAGLHRESAGELLYQGRPAAQLRGADRLAYVLGVQMIFQDPQASLNPRQRLRQILAEALKVHKLAPPAEIPARVDRALAEVGLDREYRERYSHQISGGQRQRIGIARALMVEPRFLVCDEPVAALDVSIQAQVINLFMDLREQRGLTYLFISHDLGVVRHISDRVAIMYLGKIVEQASSAEIFAHPNHPYTQALMAEVPDVGRRGRVFTPIRGEIPSPLDPPPGCTFHPRCPHAMPRCREQAPVLREIAPGHVSACHLNDTAS
>CP020651.1|AWP86728.1|4755244_4756228_+|methionine-ABC-transporter-ATP-binding-protein
MKDILLDVRGLRTAFHTEAGAWPAVDGVDLVVRRGEIVGLVGESGSGKSVTGFSLLGLIDPPGEVVEGEIRFKGKDLRKLGEEQMRQLRGNRIAMIFQDPLMTLNPVLRIGEQMAEAILTHENVPRAQAMERCREALEMVGIPSPEKRLRSFPHEFSGGMRQRVAIAIAMLNKPDLIICDEPTTALDVTIQGQILYRMQEICRQHDTALIWITHDLGVVAELADRVAVMYAGRIVESGSVDAVLDAPRHPYTRGLLESMPAQTQPGARLRQIDGMAPTLSARPWGCAFRPRCPNAVTRCTEQAPSVTQEGPRSYRCYVPIASETATA
>CP020651.1|AWP86727.1|4754327_4755248_+|peptide-ABC-transporter-permease
MANPPSNGRTRTVHPLSETPRRAQILKKLHSRPTVRGSVIALLALVALILLAPYFAPQNPYDLASLNLLDGRLPPRSPTMDGGFYWLGTDDQGRDMFSAILYGLRISLLVGLTAVVLATAIGSLVGLLAAYAGGVIDAVLMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVVVQWAHYARIMRGRALQERRKEYVEAAANLGFPAWRIMLFHLLPNCMAPVMVFATIQIANAIVLEATLSFLGVGVPVTEPSLGLLIANGFQYLLSGDYWISLFPGLALLLLILSINIVGDRLRESLDPRRA
>CP020651.1|AWP86726.1|4753342_4754320_+|ABC-transporter-permease
MALFILRRLIQSLFVLLAVSVVVFFAVYAVGDPIELLVSPEASADARQAMIARLGLDLPVWQQYGNFLWRALHGDLGNSFVHGIPAISLILQRIPATFELVLVAIVLTCTIGIPLGLVAGLHRDRPLGRGIMATSVLGFSLPNFWQGMMLILLFSVWLGWLPASGRGDTANLFGVPLSILTLDGWSHVIMPAINLAVANVALVLRLTASGVVEAQSQEYVKFARAKGIKPGRIVRRHILRNILIPVVTVIGMEFGHLIAYSTITETVFAWPGMGKLLIDSVYQLDRPVVVAYVMLVTLIFVVINLVVDILYAALDPRVQLVAPAQ
>CP020651.1|AWP86725.1|4752240_4753284_+|succinylglutamate-desuccinylase
MRRPYAFQRAVVVTPIQFEPLSGVAMSPPPAVAAVRPFELACPRLDAERVGNGATPGVWHFDAGLPGRHVLLTALIHGNELCGAWALKDALAAGLRPRRGKLTLAFCNLAAFDRFDPLNYAPARFVDEDMNRVWSADKLAAPDTQERRRARALLPWVEQADWLLDFHSMSNADEPLQLTGTQPRNIELALKLGNPAHLVADAGHAAGVRLRDYGRFGAEGENGTRSLLIECGFHGAPASRTVARDILARFLLEAGTLAADDIPPGWLADAAPRQRALRVTHAVAARSADFRFAQPWQGLERIARAGTVIGWSDGEPVATPYDDCVLIMPSLANLRPGVTVVRLAQPI
>CP020651.1|AWP86724.1|4750563_4752192_+|transporter
MKLRTTLALLATSAGLAAAPGSASAQSLKIALSSEPTSADPHYHKQTQNDAFSAHVYSSLIGRDADMKLVPALATSWKNLDDLTWEFKLRDDVKFSNGKPFTSEDVLFTICRTLNNETNVSQSYMDTTKRIADVQTPDAHTVIIKTAAPLPLLPAELARSLPIVWNGIVEHGKLTFNPKEGCGVTGPWPTVADFNNGKDAIGTGPYKLKSYVKGTGIELERNDNYWGPKPYWKDVKMVPVPNAGPRLTGLLSGDFDVIENPAARDLPRIKSNPQFGFVATPSTRLIFFQPDVGRNPSPLVKSADGKNPLQDLRVRQAISMAIDRKTIVTRLMDCIATPAYQYMPDGMFGGVPNAPEIKYDPEGAKKLLAEAGYANGFELTISTPNDRYVNDGQIAQAVAQYLSRVGIKANVDAMTASLYFPKRAKREFSFSMGGWPAEVGEASALFQLWVASLDSPRSLGTSNYGGFSNAEFDKVFTEALVTVDVAKREKLLQQSTQIALDNVPLIPLHFESSIWAFRKGLTYEGRRDQFTLAMSVQPADQK
>CP020651.1|AWP86723.1|4750030_4750267_+|hypothetical-protein
MSDLTLSHNARLTDSLERELLRGAMEDQSNTIRPLAAVKAAAVGVGRGVRAVFAFIDEVNESMNRARAQSAHYTGSQW
>CP020651.1|AWP86722.1|4749042_4749903_+|NAD(P)H-hydrate-dehydratase
MDTSSSSLPAIERQHLPALFAARPTDAHKGSCGTLGVIGGGPGMVGAALLAARAGLKVGAGKVLVGLVAETPPLPCDPMQPELMLRDFRGLLEAGLGIDAWTAGCGCGMDALAANALSELFQLRGDAALVLDADGLNLLAAGAVQPRWGNAPVVLTPHPAEAGRLLGLSTEAVQADRPAAARTLAARYGAWVVLKGAGSIVCDPAGACRINRTGNPGLATAGTGDVLAGILGALLAQRIAPEQAVPGAVWLHGAAADALVTHGIGPIGLTAGELADSARRLRNSRA
>CP020651.1|AWP86732.1|4759451_4761521_-|ATP-dependent-DNA-helicase-Rep
MSASDTSIGSGLNPSQKEAVLYLDGPCLVLAGAGSGKTRVITQKMAYLLRECGYMGRNIVALTFTNKAAREMAERVKTLVDPKLAKGLTISTFHALGVRLLREEAAHAGLKPQFSILDADDAMSIIQELLATTDRGRLREVQSIISLWKNALLTPDQAAAAAITPTEVEAVTVYRGYAATLAAYQAVDFDDLIRIPAELLERNEEVRTRWQNRVRYLLVDEYQDTNVCQYRVVQLLTGVRAMFTAVGDDDQAIYAWRGATIENLAKLTTDYPNLKLIKLEQNYRSVQRILAAANNVIERNPKLFEKKLWSDLGHGEPIIVSPMNGDEHEAESIAMKVSAARFERQAQWKDFAILYRSNHQSRVLEQALRNLKIPYTISGGQSFFDKAEVRDILAYLRLVANDEDDPAFIRAATTPKRGIGQGTLQTLGQYAAQRQCSLLAAVDEAGLESLLAPRQLEPLRTFAEFVRRIQWRAGRGVEGQPARAPEPAGQILDDLLSAIQYERYLYDMLEERPAQTRWQNVLELTGWLKRKAEEDGMTLFDLVQHVALVTMLERGEEEEPDAVKLSTLHASKGLEYPHVYLAGVEEGLLPHLGKDDEDSGDPARAAETLATRIQEERRLMYVGITRAQRSLNLSWCKKRRRAREDVVREPSRFIEEMGLGDAKVQEDEATRAMSPKERLGMLKALLKKD
>CP020651.1|AWP86733.1|4761563_4763666_-|primosomal-protein-N'
MSDASSADPALPAADAAGVWVRVALDVPLPGPFDYRSAAPLPLGARVIVPFGRRKLVGVVVEHPAQPSIDPAQVREVEQPLEDLPPMPADWMRLARFAADYYQRPLGEVMLPVLPPPLRKPSAYQGKRSGLGPVARLDARKPRAEAAVAAEPDQAPELNEAQREAVDTIGALSAFQPVLLHGVTGSGKTEVYLHAAARVLQAGRQVLLMVPEINLTPQLEGALRARLEALVGPQGVAILHSGLADGERVQAWARAQRGQARLLLGTRMSIFAPLPELGLIVVDEEHDPSYKQQEGLRYSARDLAIWRARDLDIPVVLGSATPSLESWQHAERGRYLRLTLPGRARASSLPEIRLIDTRRLQLKQGLAPQFIEAIGQRLERGEQSLVFLNRRGYAPVLHCASCAWVSHCPRCSTFTVLHRGPGAGGYRLQCHHCGYQAPVPRACPECGDQDLEPMGRGTQRIEEQLAEWFPQARIARIDADSTRRKGSAQALFAAVHAGEVDIMVGTQMVAKGHDFARLGLVGVLNADSMLFAHDFRAPERLFAQLMQVAGRAGRHAAGAQVLIQTGYPEQPVYQALLRHDYAGFARHALQEREDTGLPPFAYQALLTAEARELTVAQGFLQRARDLATGEPWPGVDAITLYDPVPLRVVRVAHVERAQLLIESTSRPALQGFLTAWAACLPQLAAEARVRWQLEVDPLEI
>CP020651.1|AWP86734.1|4763972_4765049_-|uroporphyrinogen-decarboxylase
MSVAPLKNDVFLRALLREPVPYTPIWLMRQAGRYLPEYNATRARAGSFMGLAQNPDYACEVTLQPLARYPLDAAILFSDILTVPHAMGLGLDFAPGEGPRFAHPVRDESDVAKLAVPDMDSLRYVFDAVRTIRRELDGRVPLIGFAGSPWTIACYMVEGRGSDDYRLIKSMLYGRPDLLHRILEINAEATRHYLNAQIDAGAQAVMLFDSWGGVLADGLFQQFSLAYTRRVVEGLTREREGRRVPVIVFTKGGGQWLEEIAACGCDAVGLDWTVNLGTARRRVADAVALQGNLDPMTLFGGAQAVRAEARRTLDAFGPVGKGGHVFNLGHGISQYSPPEVVSELVDEVHTYSRALHAG
>CP020651.1|AWP87333.1|4765124_4766006_-|hypothetical-protein
MRALLECAVLVMPDQPSWVGAWLAAVRSPEARLADRLRLHEYPLSGGRDGLALGQAAMSLRRFDALLLPVQASTLGWARLVLAQASPALSTPVLVLVRDLTAPAIADLLRLGARDFLRVPACLEELRVRASRAWRAIPPPAAGARAAVPVPGAEPGGGRGPGAPTDPGEGDGYRLPGMPETADASAAAPCMLAQTRAPYAATLGDARMAVQRELPFRQAKAQVVGRFERAYLRGALARHGGNVAQAARAACKHRRAFWALMRKHGIDARPYREGVAGAWPYETAPPRDPADEA
>CP020651.1|AWP86735.1|4766188_4766611_-|ATP-synthase-epsilon-chain
MATLHVDVVSAEEAIFTGEAKFVVLPGEAGELGILPGHTPLISRIRPGTVKIVRADEGEENIFVAGGILEVQPGSVTVLADTAIRAADLDEARAVAAREKAEEALRNAKDKADIAVVEAELAMLAAQAVAARKLRQGRTH
>CP020651.1|AWP86736.1|4766620_4768021_-|ATP-synthase-subunit-beta
MSNGTIVQCIGAVVDIQFPRDNMPKIYEALTLVDEGSSFAEKGLTLEVQQQLGDGVVRTIALGSSDGLRRGMQVAGTGAPISVPVGHGTLGRIMDVLGRPIDEAGPIASDEKRAIHQPAPRFDELSPSVELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKQHSGLSVFAGVGERTREGNDFYHEMEESNVLDKVAMVFGQMNEPPGNRLRVALTGLTMAEKFRDEGRDILFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSIQAVYVPADDLTDPSPATTFQHLDSTVVLSRDIAALGIYPAVDPLDSSSRQLDPQVVGEEHYQVARGVQQTLQRYKELRDIIAILGMDELSPEDKQAVARARKIQRFLSQPFHVAEVFTGSPGKYVSLAETIRGFKMIVDGECDALPEQAFYMVGTIDEAFEKAKKLQ
>CP020651.1|AWP86737.1|4768063_4768969_-|ATP-synthase-subunit-gamma
MPGIKEIRTKIKSVQNTRKITKAMEMVAASKMRKAQERMRAGRPYATKVREIAAHLMQANPEYSHPYLVEREVKAVGVVLVTTDKGLCGGLNTNISRVTLSKLKEFEQRSIKVQATAFGNKGLGLLTRIGAKLVSQEVQLGDKPDLDRLLGAIKVQLDDYLEGRIDALYVATTRFVNTMRQEPVFLRLLPLSNGLDDPFQSGVETLAKTAEIKSDYSWDYIYEPDAKSVIDDLLQRYVEGLLYQAVAENMASEQSARMVAMKSASDNAKKVIGDLQLVYNKTRQAAITKEISEIVGGAAAV
>CP020651.1|AWP86738.1|4769067_4770609_-|ATP-synthase-subunit-alpha
MQLNPSEISELLKSRIEGLGASTDVRTQGTVVSVTDGITRIHGLSDVMQGEMLEFPNNVFGVALNLERDSVGAVVLGDYTGVSEGDQVKTTGRILEVPVGPELKGRVVNTLGDAIDGKGPINTTQTDIIEKVAPGVIARRSVSQPLQTGIKAIDSMVPIGRGQRELIIGDRQTGKTAVAVDTIISQKGKGVTCVYVAIGQKASTINNVVRKLEEHGAMEYTIVVAAAASDSAAMQYLAAYAGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNEEYVEKFTNGAVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGVRPAINAGISVSRVGGAAQTKVIKKLSGGIRTDLAQYRELAAFAQFASDLDDATRRQLERGKRVVELLKQPQYQPLQVWELAVSLYAVNNGYLDDVDVAQILAFEKSLKDHLKAKHAALIQRIEDTKELSKDDEAELAAAVQDFKKHGAF
>CP020651.1|AWP86739.1|4770643_4771183_-|ATP-synthase-subunit-delta
MAELSTVARPYAEALFGAARDDKAGLAVWADLVSEMAQVAANPDVREAMADPRLDDKQRSEVFTGLIKSQLPQAARNFIELLVKNDRLLLLPVIATQFVALKNRHEGTAQAEITSAFELSDAQVKELIAALELKFGLKLKPHVSVDQELIGGVRVAVGDQVLDTSVKAQLARLRDTLAA
>CP020651.1|AWP86740.1|4771195_4771666_-|ATP-synthase-subunit-B
MNLNATIFFQMLVFFVLGWFTMKFVWPPLTKAIDERRQKIADGLAAAEKGKADLAQAQARVSLIEASAKSETHARIIEAEKQAASVIEQARREAEAERARIVAQAAQDAAQEVQRAREALRDDVAALAVKGAEQILKREVDARAHAELLNQLKAQL

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP020651_6	6.1|3248458|50|CP020651|CRISPRCasFinder	3248458-3248507	50	CP020651.1	1486880-1486929	0	1.0
CP020651_6	6.1|3248458|50|CP020651|CRISPRCasFinder	3248458-3248507	50	CP020651.1	3091251-3091300	0	1.0
CP020651_6	6.1|3248458|50|CP020651|CRISPRCasFinder	3248458-3248507	50	CP020651.1	1442262-1442311	1	0.98
CP020651_6	6.1|3248458|50|CP020651|CRISPRCasFinder	3248458-3248507	50	CP020651.1	1442345-1442394	1	0.98
CP020651_9	9.1|4533267|33|CP020651|CRISPRCasFinder	4533267-4533299	33	CP020651.1	3963477-3963509	1	0.97
CP020651_6	6.1|3248458|50|CP020651|CRISPRCasFinder	3248458-3248507	50	CP020651.1	3269363-3269412	2	0.96

1. spacer 6.1|3248458|50|CP020651|CRISPRCasFinder matches to position: 1486880-1486929, mismatch: 0, identity: 1.0

ggcccccacgctgcgcccgctgtgcgggcttgctgccccccaagggggct	CRISPR spacer
ggcccccacgctgcgcccgctgtgcgggcttgctgccccccaagggggct	Protospacer
**************************************************

2. spacer 6.1|3248458|50|CP020651|CRISPRCasFinder matches to position: 3091251-3091300, mismatch: 0, identity: 1.0

ggcccccacgctgcgcccgctgtgcgggcttgctgccccccaagggggct	CRISPR spacer
ggcccccacgctgcgcccgctgtgcgggcttgctgccccccaagggggct	Protospacer
**************************************************

3. spacer 6.1|3248458|50|CP020651|CRISPRCasFinder matches to position: 1442262-1442311, mismatch: 1, identity: 0.98

ggcccccacgctgcgcccgctgtgcgggcttgctgccccccaagggggct	CRISPR spacer
ggcccccacgctgcgcccgctgtgcgggcttgctgccccccgagggggct	Protospacer
*****************************************.********

4. spacer 6.1|3248458|50|CP020651|CRISPRCasFinder matches to position: 1442345-1442394, mismatch: 1, identity: 0.98

ggcccccacgctgcgcccgctgtgcgggcttgctgccccccaagggggct	CRISPR spacer
ggcccccacgctgcgcccgctgtgcgggcttgctgccccccgagggggct	Protospacer
*****************************************.********

5. spacer 9.1|4533267|33|CP020651|CRISPRCasFinder matches to position: 3963477-3963509, mismatch: 1, identity: 0.97

gcctgcaagatttcatggcatctgcccgtgcgt	CRISPR spacer
gcctgcaagatttcatggcgtctgcccgtgcgt	Protospacer
*******************.*************

6. spacer 6.1|3248458|50|CP020651|CRISPRCasFinder matches to position: 3269363-3269412, mismatch: 2, identity: 0.96

ggcccccacgctgcgcccgctgtgcgggcttgctgccccccaagggggct	CRISPR spacer
ggcccccacgctgcgcccgctgcgcgggcttgctgccccccgagggggct	Protospacer
**********************.******************.********

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	2308520 : 2316586	9	Moraxella_phage(28.57%)	tRNA	NA
DBSCAN-SWA_2	3619340 : 3641709	30	Pseudomonas_phage(18.18%)	terminase,tail	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>CP020651|2308520:2316586|DBSCAN-SWA
TATGATGCACACGCTTGCCGCCGCCTGCCGCCACCAGGAAGAAATCAAGAAAAGCCGCTTTGCCGCCTATGCCGCGCCCGTGGGCACGATCGCCGAGGCCATGGCGCATTTCGCTGCGCACAGCGACCCGGCGGCCACGCATAATTGCTGGGCCTACCGCATCGGCAACGAATACCGCTTCAATGACGACGGCGAGCCGGGCGGCACGGCCGGGCGGCCCATCCTGCAGGCCATAGACGGGCAGGGGCTGGACCGCGTGGCGGTGCTGGTGGCGCGCTGGTTCGGCGGCATCAAGCTGGGCGCAGGCGGCCTGGTGCGCGCCTATGGCGGCTGCGCCGCCAACTGCCTGCGCGCCGGCGAGCGCTTGCCGGTCATCGCGCTGGCGACGGTGCGCTGCCGCTGCGGCTTCGCCGAGCTGCCGCTGCTGCAGGCGCGGCTGGCGCAGGCGGGCGCCAGCGTGCGCAGCGAAACCTTCGACGCCGACGGCGCGCAACTGGAGCTGGACGTGCCCTGCGCCGCGCTCGAAGAGCTGGCGCGCACGTTCGCCAACATCACCCGCGGGCGCGGCGGCTGGGACGTGCAGGCCTGAGCCAGGCCCGCCGTGGCCTCAGGCCTGTTCGCCTTCGCCGTTTTCGCGCGCCTGCGCGATATCGCGGTGCACCTCGGCCATGTCGACTTCCTTGACCTTGGTCAGCAGCTCGCCGAGCTGGCCGGCCGACAGGGCGCCGGGTTGCGAGAACAGCAGGACCTTCTCGCGAAACACCATCAAGGTCGGGATCGAGCGGATGCCCAGCGCGCCGGCCAGCTCCTGTTCGACGTCGGTATTGACCTTGGCGAAGGTCACGTCGGGGTGTTGCTCGGCCGCCTGCTCGAACACGGGGGCGAAGCCGCGGCACGGGCCACACCAGGGGGCCCAGAAGTCGATGATCAGGGTGCCGTCGGGCGTGATGGCGTCCTGGAAGGTGTCCTTGGTCAGTTCAACGATGCTCATGCGTGTCGTCCTTGCCGCCCGCGTAGGGTGGCGTCTGGGGCCCGTGGGCCCGGTTGGCGCGGCCGGGGCCGCGCAGTGGATGTTCCGTCCGTGGTCGGTGGGCGAAACGCGTGGCGCGATCGCGCGCCGTGCCGGTCAGGCGTTCGCGGTGCGGGTTGATACGCCTGCGTCCTGCTTGAGCGAGGCGACGATCTCGTACGAACGCAGCCGATCGGAAAAGTCGTAAAAATCGGAAACGATCATCACCTCGTCGGCCTGGGTCTGCGCGACCAGGCTCTCCAGTTCGCGCTTGACCGTATCGGGGCCGCCAACGATGGCCGCGCCCAGTCTCTGTTGGACCGCGGAGCGCTCCCACTCGTTCCATATGCCGTCCATGCTTTCCACGGGCGGCTGCAGCGGCAGGCGGTTGCCGCGGATCAGCGACAGGAATTTCAGTTGCTGGGTGGTGGACAGGAAATGCGCCTGCTCGTCGGTGTCGGCCGCCACCACCGGCACGCCTATCATGGCATGGGGGCGCGCCAGCGTCTGCGACGGCTTGAACAGTTGCCGATACAGGCGCATGGCGGCCATGCCTTCGGGCGAGAAGTGGCCCGCGAACGAGAAGGGCAGGCCCAGCTCGGCGGCCAGCCGCGCGCTGAAATCGCTCGAGCCCAGCAGCCAGATGGGCACGTCGGTGCCGGCGCCGGGAATCGCGCGCACCGGCTGGCCCGGCCGCGCCGGCGCGAGGTACGCGCGCAGCTCGTGCAGCAGTTCGGGAAAGTCCAGGCCGCTGCGCGGCCCGCGCCGCAGCGCCTGCTGGGTGGCCCCGTCGCTGCCGGGCGCGCGGCCCAGGCCCAGGTCGATGCGGCCGGGAAACAGGCTCTCCAGGGTGCCGAACTGCTCGGCGATGATGAGCGGCGCGTGGTTGGGCAGCATCACGCCGCCCGAGCCCACCCGCAGCGTGCTGGTATGCGCGGCGACGTGGCCGATCAGTACCGCCGTGGCGCTGCTGGCCACGCCGGTGATGTTGTGGTGTTCGGCCAGCCAGAAGCGGCGATAGCCCCAGCCTTCGACGTGGCGCGCCAGGTCGACGGTGTTGCGAAACGCCTGCGCGGCCGTGCCGCCCTGCACGATGGGGGCAAGGTCGAGGACCGAGAACGGCACGCTGGCCAATACACTCATGCGGGTGCTCCGGTTGTGTCGCGGCGCGGCGCGCCCGACGGGTCAGGAATATATGGAGAGTGTATCGGCGATTTCAACCGCGCACCCGAACAACCTTGGGCGCCATCGGGTCGATAGTCTCGCTGTATCGCGGCGATTGAAGGCCTCGAAAGCAGGCAGGCCGCGCGAGGCGGCCTGCTTGCGGGGCGAGGCGCGCGGCCCGGCCTTATTCGGGGAAGAAGGCGTAGCGGACGATGAACAGGATCGCCACCAGCCAGGTGGCCGGGTGCACCTCGCGGATGCGGCCGGTGCAGGTCTTGAGCACCACGTAGCTGATGAAGCCGAAGGCCAGGCCGTTGGCGATGGAGTACGTGAACGGCATGACCAGGGCGGTCAGCGCGGCCGGCGTGGCCTCGGACACGTCGTTCCAGTCGATGTCGATCAGCTCGCGCATCATCAGCCCGGCGACATACAGCAGCGCGGGCGCGGTGGCGTAGGCGGGCACCGAGCCGGCCAGCGGCGCGATGAACAGCGCGGCCAGGAACAGCAGCGCCACGACCAGCGCCGTCAGGCCGGTGCGTCCGCCCGCCTGTACGCCCGAGGCGCTTTCCACATAGGCGGTGGTGCTGCTGGTGCCCAGCATCGAGCCGGCCACGATGGCGGTGCTGTCGGCAAACAGCGCGCGTCCCAGGCGGTTGGGGCGGTCTTCCGGCACCAGGCCGGCGCGCTTGGCGATGCCCATCAGCGTGCCGGTGGCGTCGAACACCTCGACCAGCACGAACACCAGGATCACGTGCACGAAGCCGGTGTGCAGGGCGCCCAGGATGTCCAGTTGCATGAACGTCGGGGCCAGGCTGGGCGGCGAGGAGAAGATGCCGTTGAACTGGTTGTAGCCCAGCAGCATGGACAGCACGGTCACCGACAGGATGCCGATCAGGATCGCGCCGCGCACGCGCAGCGCATCCAGCGCCGCGATGATGAAAAAGCCCAGGATGGCGAACAGCGGGCCGGGCTCGCGCAGGTCGCCCAGCGTCACCTTGGTGGCGGGGTGCGCGACGACGATGTTGGCGTTGGACAGCGCGATGATGGCCAGGAACAGCCCGATCCCGGCGGCGATGGCGCTGCGCAGCGAGTGCGGGATGCCGCGGATGAGCCAGGCGCGGATGCCCGAGATGGTCAGGAACAGGAAGATGACGCCCGAGATGAACACGGCGCCCAGCGCCTGCTCCCAGGTGTAGCCCATGGTCTTGACCACGGTGAACGCGAAGAACGCGTTCAGGCCCATGCCCGGCGCCATGCCGATCGGCCAGTTGGCCACCAGCGCCATGATCAGCGAACCCAGGGCGGCGGCCAGGCAGGTCGCCACGAACACGGCATTGCGATCCATGCCGGTGCTCGACAGGATGTCGGGGTTCAGGAAGATGATGTACGACATGGTGAGGAATGTCGTCAGCCCAGCCACGATCTCCGTGCGTACGGTCGTGGCGTGGTCACGCAGTTGGAATAGCTTCTCCAGCATGGAAGTCCCCGGGGGTTTGAGAGCGGTTGTTGTGTGCTTGCGCCGGCGCCGCCTGCCGCGCAGGCGATAATGTAAGCGCAAAACCCGTATTTTTGCACCAGGGCCCGCGGACCCTGGTTGTAAACTCTGCGCCCATGATCATTCTCGGCTTTGAAAGCTCGTGCGACGAAACCGGCGTGGCCGCCGTCTGCACCGAGCGCGGCCTGCTTGCGCACGCCCTGCATACCCAGATCGCCATGCACCAGGAATATGGTGGCGTGGTGCCCGAACTCGCCTCGCGCGACCATATCCGGCGCGTGGTGCCCCTGACCCGCCAGGTGCTGGCCGAGGCCGGCCTGACGCTGGCCGACGTGGGCGCGGTGGCCTACACCGCCGGGCCGGGCCTGGCCGGCGCCTTGCTGGTGGGCGCCAGCGTGGCCCAGGCGCTGGCCTGGTCGCGCGCGCTGCCGGCCATCGGCATCCATCACCTGGAAGGACATCTGCTGTCGCCGCTGCTGGCCGAGCCGCGTCCCGAGTTTCCGTTCGTGGCCTTGCTGGTCTCGGGCGGGCATACCCAGCTGATGCGGGTCGACGGCGTGGGCCGCTACGAACTGCTGGGCGAGACGCTGGACGACGCCGCCGGCGAGGCCTTCGACAAATCGGCCAAACTGATGGGCCTGGGCTATCCGGGCGGCCCCGCGCTGGCGCGCCTGGCCGAGCAGGGCGACGCCAGCCGCTACGACCTGCCGCGCCCCATGCTGCACAGCGGCGACCTGGATTTCAGCTTCAGCGGATTGAAGACCGCGGTCCTGACCCGTGTGAAAGCGGCCACGCGCGATGGCGGCGAACTGGGCGAACAGGACCGCGCCGACCTGGCGGCGGCAACGCAGGCCGCCATCGTCGAGGTGCTGGCGGCCAAGGCGATCCGCGCCTTGAAGCAGACGGGCCTGCGCCGCCTGGTGGTGGCCGGCGGGGTGGGCGCCAACGCGCTGCTGCGCGCGCATCTGGCGCGCGCGCTCAAGCCCTTGCGGGCCGAAGCCTATTTTCCGCCGCTGTCGCTGTGCACCGACAATGGCGCCATGATCGCGTTCGCGGCGGCCGAGCGGGTCAAGGCCGGACTGGCCGACCTGCGCGAGGGCGACCACGCCTTCACGGTGCGGCCGCGCTGGGACCTGGCGGATATCCAGGCCGGGTAGGCTGACGGGGGGCCTGTCCCCGCGGGGGCAGGCTCCTGAGTGGGTTACTTCTTCTTCCCGATGCGGCTTTCGGTGCCCTTGAGCAGCCGCGCGATGTTGGCGCGGTGGCGGTAGAACAGCAGGGCGCTGATGACGGCGATGGCCAGGCCGACTTCCAGCCGCGCATGCCAGGCTGCGCCCGAGCCGAATACGTAGTAGACGGGCGCGAAAAATGCGGCGACCAGGGCCGCCAGGGACGAATAGCGCGAGAACACGGCCACGATCAGCCAGGTTGCGATGGTGGCCACGGCCAGCCATGGCTCGATGGCCATCAGTACGCCCAGCGCCGTGGCGACGCCCTTGCCGCCCTTGAAGCGCAGGAACAGGGGGTAGAGGTGGCCGAGGAACACCGCCAGCGCCACCAGCGCGTAGGCGCCCCAGGAGAGTTCGGGGACCAGCGCGCGGGCCAGCCACAGCGCGAACCAGCCCTTGGCCGCGTCGCCCAGCAGGGTCAGCGCGGCGGCGGTCTTGTTGCCGGTGCGCAGCACATTGGTGGCGCCCGGATTGCCGGAGCCGTAACTGCGCGGATCCTGCAGCCCCATCAGCTTGCTGACCACGACGGCAAAGGGGATGGAGCCGATCAGATAGGCCAGGACAATCAGTGCCGAACTGGACAGGAGCGAAGGGGCGGTCAGGACCATGGTGGCAGGCATTCCGTTACGGTTGCGTCGTTTGGCTGCGGATTCTACCTCGGGCGGCGATTCTGACGCGATGATGCCGCTTCATGACGGTACAATCGGTCGCGGTTTGTGGCGATCCCCACGATTCAGGAAGATTGATGCGTATTCTGGTTTCAAACGACGATGGTTACAACGCCCCCGGGCTGGAAGCGCTGGTCGAGGCGCTGTCCGGGCTGGGCGAACTGACCGTGGTCGCGCCGGAGACGAATCACAGCGGCGCCTCGAATTCCCTGACCCTGAACCGGCCGCTGACGGTGCGCACCGCTTCCAACGGCTTCATCTACGTCAACGGCACGCCGTCCGATTGCGTGCACGTCGCCCTGACCGGCCTGATGGATGCGCGCCCCGACCTGGTGGTGTCCGGCATCAACAATGGCGCCAACATGGGCGACGACACGCTTTATTCCGGCACGGTGGCCGCGGCCAGCGAGGGCTACCTGTTCGGCATTCCCTCGATCGCCTTCTCGCTGATCGAAAAAGGCTGGCAGCACATCGAATCGGCCGCGCGCGCCGCCCGCCAGGTGGTCGAGCGCCAGATCGCGCAGCCGCTGGCCGCGCCGGTCCTGCTCAACGTCAATATCCCCAATCGCCGCTACGAAGACATGAAAGGCTACGCCGTCACGCGGTTGGGCAAGCGCCATCCGTCCGAGCCGGTGGTGCGTACCACCACGCCTTATGGCGACACGGTGTACTGGATCGGCCCGGTCGGCCTGGCCGCCGACGCCACGCCGGGGACGGACTTCCACGCCACGGCGCAGGGGCAGGTCTCGGTGACGCCGCTGCGCCTGGACCTGACCCAGCACAGCCAGCTTGACGATGTGCGCAACTGGGCGGAGCCGCTATGCGTAAACGCGTAGACCCGCCGGCCGGCGGCCGCCTCGCGCCCGGCATCACGCCGGCCAACAGCAACACCCGCATTTCGGCCGGCGCCTTGCCGCGCGCGCCTGCGCAGCCCGCGCCGCTGGCCAGCGGCAACCTGGGCCTGAACTCCGACCGGCTGCGCCAGGCGATGGTGCAGCGGCTGCGCACGCAGGGCATCGTCGACGAACGGGTGCTCAACGCCATGGCGGCGGTGCCGCGCCATCTGTTCGTCGATGAAGCGCTGGCCAGCCGTGCCTACGAAGACGCGGCGCTGCCCATCGGGCACTCGCAGACCATTTCGCAGCCGTGGGTGGTGGCCCGCATGATCGCCGCCGTCTGCGAGGACCGTGCCCCGGCCCGGGTGCTCGAGGTTGGCGCCGGCTGCGGCTACCAGGCGGCGGTACTGGCCCAGATCGTGCGCGAGGTGCATGCCATCGAGCGCATCCGCGGCCTGTACGAGCTGGCGCGCGGCCATCTGCGGGCGCTGCGCCTGGCCACCCGGGTGCGCCTGATCCATGGCGACGGCATGCTGGGCGTGCCCGGCGTGGCGCCGTTCGATGCTATTGTTGTGGCTGCGGCGGGCCTGGCCATTCCGCAGGCCTTGCTGGATCAGCTTGCGCCGGGCGGGCGGCTGATCGCGCCCGAAGGGTCCACCCACCAGCGGCTGGTGCTGATCGAACGCACCGGGGCCACCGCCTGGAGCCGAAAAGAACTCGAAGCTGTACGTTTTGTGCCCCTCAGGGCCGGAATACAATCTTGAGCAAACAGGAGAATCGTATGCTCAACGGGCAGTTGCAACTGACCGAATCCCAATCCGTGGCTGGCGCATCCGCCGCCGCCGCTTCCCGACCCGTTCTCTGGGCGGGCGTGCTGGCCATCGCCTTGCTGGCCGGCTGCGCCTCGAAGGGCCCGCGCGCGCCCGTGGTCGACCTCACCGGACAGCCCGGCGCCTCCGGCCCGACCGACGGCAGCTATGTCGTCAAGCCTGGCGATACGCTCTACAAGATCGCGCGCGCCAACAATGTCGATATCGAAAACCTCAAGCGCTGGAACAACCTCACCGATCCCAACCAGATCAGTGTCGGCCAGGTGCTGCGCCTGTCGAGCTCGGGCGCCGGCGGCGCGCAGACCACGCCGGTGACCTCCTCCAAGCCGCAACCCAAGCCGCTGGACCAGGGAAGCGCCGAAACGCCGGCCGGCGGCATGGAAGCCGGCGCCGGCGGCGAAACCGGCGGGGCCACCACCCCGCCCGCGGCAACGGTGCCCGATCCCAAGCCCGCGCGCGCGGCCGATGCCGCCGTCATCAACTGGGGCTGGCCGGCCAATGGCGCCATCCTGCAGACCTTCAACAGCAACACCAAGGGCATCGACCTGGCCGGCTCGCTGGGCGATCCGGTGATCGCGGCGGCCGATGGCAAGGTGATGTACAGCGGCAATGGCGTGCGCGGCCTGGGCAACCTGATCATCATCAATCACCAGAACGGCTTCATCACGGCCTATGCGCACAACCGCGCGCTGCTGGTCAAGACCGGCCAGAACGTCAAGCGCGGGGCCAAGATCGCCGAGATCGGCGAGACCGACACCACGTCGCCGCGCCTGCATTTCGAGATCCGCCGCCAGGGCACGCCGGTCGACCCGATGCAGTATCTGCCGCCGCGATGA

Protein sequences of DBSCAN-SWA_1

>CP020651|2308520:2316586|2312303_2313344_+|AWP84578.1|tRNA|DBSCAN-SWA
MIILGFESSCDETGVAAVCTERGLLAHALHTQIAMHQEYGGVVPELASRDHIRRVVPLTRQVLAEAGLTLADVGAVAYTAGPGLAGALLVGASVAQALAWSRALPAIGIHHLEGHLLSPLLAEPRPEFPFVALLVSGGHTQLMRVDGVGRYELLGETLDDAAGEAFDKSAKLMGLGYPGGPALARLAEQGDASRYDLPRPMLHSGDLDFSFSGLKTAVLTRVKAATRDGGELGEQDRADLAAATQAAIVEVLAAKAIRALKQTGLRRLVVAGGVGANALLRAHLARALKPLRAEAYFPPLSLCTDNGAMIAFAAAERVKAGLADLREGDHAFTVRPRWDLADIQAG
>CP020651|2308520:2316586|2309645_2310671_-|AWP84576.1|DBSCAN-SWA
MSVLASVPFSVLDLAPIVQGGTAAQAFRNTVDLARHVEGWGYRRFWLAEHHNITGVASSATAVLIGHVAAHTSTLRVGSGGVMLPNHAPLIIAEQFGTLESLFPGRIDLGLGRAPGSDGATQQALRRGPRSGLDFPELLHELRAYLAPARPGQPVRAIPGAGTDVPIWLLGSSDFSARLAAELGLPFSFAGHFSPEGMAAMRLYRQLFKPSQTLARPHAMIGVPVVAADTDEQAHFLSTTQQLKFLSLIRGNRLPLQPPVESMDGIWNEWERSAVQQRLGAAIVGGPDTVKRELESLVAQTQADEVMIVSDFYDFSDRLRSYEIVASLKQDAGVSTRTANA
>CP020651|2308520:2316586|2308520_2309108_+|AWP84574.1|DBSCAN-SWA
MMHTLAAACRHQEEIKKSRFAAYAAPVGTIAEAMAHFAAHSDPAATHNCWAYRIGNEYRFNDDGEPGGTAGRPILQAIDGQGLDRVAVLVARWFGGIKLGAGGLVRAYGGCAANCLRAGERLPVIALATVRCRCGFAELPLLQARLAQAGASVRSETFDADGAQLELDVPCAALEELARTFANITRGRGGWDVQA
>CP020651|2308520:2316586|2314161_2314920_+|AWP84580.1|DBSCAN-SWA
MRILVSNDDGYNAPGLEALVEALSGLGELTVVAPETNHSGASNSLTLNRPLTVRTASNGFIYVNGTPSDCVHVALTGLMDARPDLVVSGINNGANMGDDTLYSGTVAAASEGYLFGIPSIAFSLIEKGWQHIESAARAARQVVERQIAQPLAAPVLLNVNIPNRRYEDMKGYAVTRLGKRHPSEPVVRTTTPYGDTVYWIGPVGLAADATPGTDFHATAQGQVSVTPLRLDLTQHSQLDDVRNWAEPLCVNA
>CP020651|2308520:2316586|2313388_2314036_-|AWP84579.1|DBSCAN-SWA
MPATMVLTAPSLLSSSALIVLAYLIGSIPFAVVVSKLMGLQDPRSYGSGNPGATNVLRTGNKTAAALTLLGDAAKGWFALWLARALVPELSWGAYALVALAVFLGHLYPLFLRFKGGKGVATALGVLMAIEPWLAVATIATWLIVAVFSRYSSLAALVAAFFAPVYYVFGSGAAWHARLEVGLAIAVISALLFYRHRANIARLLKGTESRIGKKK
>CP020651|2308520:2316586|2309126_2309510_-|AWP84575.1|DBSCAN-SWA
MSIVELTKDTFQDAITPDGTLIIDFWAPWCGPCRGFAPVFEQAAEQHPDVTFAKVNTDVEQELAGALGIRSIPTLMVFREKVLLFSQPGALSAGQLGELLTKVKEVDMAEVHRDIAQARENGEGEQA
>CP020651|2308520:2316586|2310876_2312169_-|AWP84577.1|DBSCAN-SWA
MLEKLFQLRDHATTVRTEIVAGLTTFLTMSYIIFLNPDILSSTGMDRNAVFVATCLAAALGSLIMALVANWPIGMAPGMGLNAFFAFTVVKTMGYTWEQALGAVFISGVIFLFLTISGIRAWLIRGIPHSLRSAIAAGIGLFLAIIALSNANIVVAHPATKVTLGDLREPGPLFAILGFFIIAALDALRVRGAILIGILSVTVLSMLLGYNQFNGIFSSPPSLAPTFMQLDILGALHTGFVHVILVFVLVEVFDATGTLMGIAKRAGLVPEDRPNRLGRALFADSTAIVAGSMLGTSSTTAYVESASGVQAGGRTGLTALVVALLFLAALFIAPLAGSVPAYATAPALLYVAGLMMRELIDIDWNDVSEATPAALTALVMPFTYSIANGLAFGFISYVVLKTCTGRIREVHPATWLVAILFIVRYAFFPE
>CP020651|2308520:2316586|2315701_2316586_+|AWP84581.1|DBSCAN-SWA
MLNGQLQLTESQSVAGASAAAASRPVLWAGVLAIALLAGCASKGPRAPVVDLTGQPGASGPTDGSYVVKPGDTLYKIARANNVDIENLKRWNNLTDPNQISVGQVLRLSSSGAGGAQTTPVTSSKPQPKPLDQGSAETPAGGMEAGAGGETGGATTPPAATVPDPKPARAADAAVINWGWPANGAILQTFNSNTKGIDLAGSLGDPVIAAADGKVMYSGNGVRGLGNLIIINHQNGFITAYAHNRALLVKTGQNVKRGAKIAEIGETDTTSPRLHFEIRRQGTPVDPMQYLPPR
>CP020651|2308520:2316586|2314994_2315684_+|AWP87239.1|DBSCAN-SWA
MPRAPAQPAPLASGNLGLNSDRLRQAMVQRLRTQGIVDERVLNAMAAVPRHLFVDEALASRAYEDAALPIGHSQTISQPWVVARMIAAVCEDRAPARVLEVGAGCGYQAAVLAQIVREVHAIERIRGLYELARGHLRALRLATRVRLIHGDGMLGVPGVAPFDAIVVAAAGLAIPQALLDQLAPGGRLIAPEGSTHQRLVLIERTGATAWSRKELEAVRFVPLRAGIQS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWP84574.1|2308520_2309108_+	thymidylate synthase	A0A1X9I5T8	Streptococcus_phage	2.8e-16	46.8
AWP84575.1|2309126_2309510_-	thiol reductase thioredoxin	V9SJ74	Achromobacter_phage	8.1e-09	25.8
AWP84576.1|2309645_2310671_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
AWP84577.1|2310876_2312169_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	1.7e-66	36.0
AWP84578.1|2312303_2313344_+|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	9.3e-92	51.6
AWP84579.1|2313388_2314036_-	glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
AWP84580.1|2314161_2314920_+	5'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	6.2e-69	51.2
AWP87239.1|2314994_2315684_+	protein-L-isoaspartate O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	4.2e-32	46.9
AWP84581.1|2315701_2316586_+	peptidase	A0A292GJG6	Xanthomonas_phage	4.6e-15	49.5

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>CP020651|3619340:3641709|DBSCAN-SWA
ATCACCGCTGGATCGCCAGCACTGCTACGCGGCCGCCTATGTAGTACGTACCATCGACCGGATGTCTGGCTTTGATCGACCAAGAGATCGTTTTCCCTCCCGGCAAGGCATCGCTGATCCAGGTAATCATGGCAGCCCCATCGGGAGGATTCGACAAAGCATTCGGGATGATCTCTCCGTCAATGGAAACAATGGTGTTACGCCCAAATGGAAACCGCCCTCCCGATTGCGCGTACTGCATAAAGACTACTACCGAACCGCCATAGGGCAGGTACAAACTACCGGTCGCAACAGTCGCCAACTCCGATCCCCCTCGCCCCAAGGACTTGGAGATGATGCTGTGAGAGCCTGTCACAACAGCACCAGATGCGAGGCGCAACGTATCGACCTGCGCGACACCTATATGGGCAGTCTTGACGTAGGCCGTGGTGAAGCTGGCCAGCTTCGCTATCAGAGACTCGGCGTTGATCCGATCGGCGCTCATAACGCCTACCACGATCTTTCCCGCGTCTAGGCTCTCGATCTGCGCACTCTTGATCCAGGCCGTCCCGATGAATGCCTTATTTAGGAAGGTTTGCCCATTCTGGACCACGAATGGCGTGGAAATCTTTCCGTTCGCTAGATTGAGGAAGGCGAAGCGATCCGCAAGAAAGTAGACCGATGTTTGCACCCGGCCGCGCTCATTCGTGTAGGCGCCGAGCGCCATGCCAGCCGCGTATACCTTGCCGTCTTGGGCGACCTGCGTCTGGACAGACCAGGTCGCCCGCAGACGTCCATCTAGGCTGGAAAGTGCCGTGCTAGTCTGCTTTACAGCCGTTGCACTCGCACCATTTGCTGCAATCGCATCTTCGACCCGACGAGCCAATGCGCCATCCTGGTTAAGGCGCTCCTCTCTTTCCTGATCCAGCTTCGCAGTGACCGTATTGATGTTGCGCCCCATCCCCGAAATGGTCTGCGTCAAATCACGTGTCAGCTGCTCCGGCCCGATCTGGCCACTCAAGTAGTCAAGAATCTTGCCCGCATCGCTACTTGCACTACCCGGCACGCCCTGCCCGTCGGGATACCATGGACCCACCTGTCCCGCCTCGTCGCGTATTCGCCCCCAGAACCAAATTCTCGTACCATGGCTCAGGCCGAATCGGGTAAAGCGGCTTTGAGGCAACCGAAACTCTCCCATCAACGAAGCATCCCCGAGGTTGGAAGTCGAAGACTCCCAAATCTCGACTGAGCTTATCCATGGGGCGTCCGGCACAGTCCACGCCAATTCAATCGCCATCACTTGGCTTACCGCCGTCAACGCGGAGAGCCTAGGCGGTGGTGCAGCGCTTGCGCTAACGTTGCCCTGCCAAGTCTTCCACGGCCCGGACAATGCGCCGACACCTCGAACCCGCACCTGCCAGGATCCCGCGCGAAGGTGGACCTCAAGACTCGGTAACTCGGCCATCCCCAGAGGCTGCCAATGTACGCCTCCATCGTCACTGGCTTCAAACTCGTAGCGATAGGCACCGGAGGCCGGCGTGGCTGATACGATCTGTTGTCCTGGTCGAGGAGCGGAAAACACCGTCACGCCATCAACAATCGGCCCCAGCGGTACGATGGGTAGCAAAGAAGGAGACGCGAACTCCGGTTCCTGCCCACCCAGTTCCGCTGTATGCACCGATGGTGCATAGTTCACCAAGTCCAGCGTCCATAATCCACCCTCGCTCGGCACCGCCCGCATTACCTGTGCAAGCAATGCCCGCCGCTCGCCTGGACCAAACGTGTAGTGGGTAGGCTCTTCAGTTTCCCCTGTAGAAATATACAAACCGTGCCCATCAACCAAATCCGCAATGCGCATCTCACGCTCGTGCGAGCCCGGCTCGACGCGAAAAGGTCCGGCGGGTCCGCCATCTCGGCCGCGCAAACTGATATAGTGGTTCTGGCCTTGCCACCACTGCAAAGGCTCGGACGTAGTAAGCAGAAGCGCACGAGGATCGTAGTCTTCCACGATTCCCGACAGCCCCCACTTGGGAACATCATGGCTGATCTCGACTAGATCGGCATAGCCCGGAATGGCTCCTTCCAGTTCCGTCTGAAAACTTGCAAAACGACGCTGGTCCCGGTTGCGGGCCAATAGTGCCATGCCCTCACGCCATGCCTGCGCACGCCCCGTCACACCCACTAGACGCAACCGATAAGGCCGCCGTTTGGCCGCACCGGGCCAAGCACACTCCACCTCGTCGTCCTTCCACGTCCTCTCGTTGACGAACTCGACAATGATGTAGTCTGGGTCGTCATGCGCTGGAAATACATAGTCAACGGAGAACGAACGCGTCACGATGTTGGCGGGCGTAAACATCTGCGTTCGCACGGACTTGGGCTCATCTCTGATGACATCTATCACGCCAGCGTGATAGATCGGTAGCGCCCGCCCAGCACGGGCGATCTGCGTCACTGCTTCCCAAAATGTCGTACTGACGTCAAAAACGCCGTCGAACCAATCGCCCCGCTCATCCCAGACTTTTGCCAAGCGATAGAGTGCCGCCAGATTGATGCGGCTGTCCGGCAGTCCTCGTCCATACTCCCGGTCCGTGCACGCATCGGCGATCGCCCAGGCAGGATTACGAGTAGGTTTGAGGTCCTGGGACCACCCTTGGACCGGATCCCAGGTTCGCAACCGCCGGGTGGCGATAATATTGATCCGCCGCGCGGTGGTTTGGTTCAGATTACCCGTCGCGCGCATAGCTACCGCCAGCATCGTGACGTTTCCATAAGTCCTCTGAGATGGCAGGTAGGACCGCAACCCTAACCATGTCACGTCGCGGATCATACGGGTAGCGCGCTCAGCAAGGTGGCCAGAATTTCGCTCTACGCTAATCTCCCAGCGACCAGGCTCTACCTTGTACCGAAATGTCCGGTATTGGGGCGTAAGTGTTGCCGCGACAATGTTCTCCCTACCCAGAACGATCGTAGTACCAATCGGCTTTCCTGAATCATCGATTTGGCGCGCGTACACATTGACGCCGGTGCCAGCCGATTCCAACGTCCCATCATGCGCCGCGTAGAACAACCCCTTTGGCAGGAGGATATCTATAGCGATTTCACTAGCCAGGGTACCCGGCGGGTTTGCTGCGAACGGCCCTTTGGGCCCGGCTCCTTCCACATTGATCGCAGGTAACTCAATACCTTGTACTTCCGCAGAAGTGACGACATTGTCTGGAAACAGCGTCACCTGCCCGCCAGGCTCCACCACCTCATACTCGACCTCCGAAAAATTTCCTATCGGAGTCTCTTCGATTCGTATCTCTTCAATTTCATAGCGCCCTTGTCCAACGCAAAACAACTGGTAGAGATGGGTCTGATTGTTGACCATCTCCGTGTAGGGTTGCGCAGCAAAATCGAGGTACGAACGATACCTTCCGTAGCGAGCAGGTATGGCTTCCATTGGACGCGCCATATTGCCCTGTGCGCTTAACGTATAGGTGGGACTGGCTTTCTCACGCTGCAGCGAGCCTGGCAACCGTGCTGGTGGAAAAAGCGAGTTCACCACCATCCCACCGACCAGACCAACGGCCGTCGCCGCTCCAGCACCAACAGTCAAAGCAGCGGCGCTAGTCGCCGCAACCCCGGCAGCGCCGGCGTACGCAGATGCCGCCCATGCTCCTACACCCGCCGTAGCTGCAGCCAGTGCCGCCATAGCGACCACTTGCAGCGGATTAGAGCCCCCACCCCCAGCCGGCAAGACAACGACCGCCACGACATCATGCTTTCTCAACCGAACGTGCCACGCCGACTGAACCTTCCAACTTCCATTGAGCTGCACGACAAAGGTCCGTGTGCGCACAAGACTCTTGCCCCGTCCGACGATAAAACCTTCCCGCCGCAACACCGTATCCAGGCGGACACCTTGTGGTGCCACGATGGTTTCTTGCCGCAAATGTGGCCGAAACGGATCGCGCTGTATCGTGATATCAGGCATGGATTCGATAGAAGATAGGCTGAGAAAAACCCATCGTGAACAGCGCGCGCATGGGAGAAAATATGACGCCCCGCCCTTCTAGCGCATGCAGTACGCCACCGCCGTCAAGGTCAAGATAAATGCCGACATGCGGATCATTTCCAGCACGCAACATCACACCATCGCCATGCTGAGGATGAGTCACAATCTTCCAGGCCCCCGTGCGCATCTTGTGCGCATACAGCGCACGTGCTTGCTCACCCAGCGCAGTTTCAGGTATACCGCCTTCAAAGTATCGCTCTCGACATTCCCTCAACAGGCCCCAGCAGTCATAAGCGTCTGGTCCTCGCCCACCCAAACGCCACATCAAGCCGATGTAGCGATTCACATCGCTGCTGGTCATCGGAACAACCCCGGAAAGCGTTCACGCACGTAGCGCTCATGTGGAAACGCCCAGTTATGGACATCAGAAAGCGTCGCTGTTCCAGACACGGAAGAACCCGTCACTGTCACCTTGTTCAATTCCATTGTGATAGGCGGGTTCATTTGAGGCATGCTAAGGTCCGTCGACAAATACGGACGATAGGTAACGTAGATGGGAAACCGTGACTGCACAGCCGCTTCGACATGATCGACGATCTGTTCGCTGGCACCGTCTATGGCAATAAGCAGCGATGGAACCTGACCTTCTTCAAAACCGGGCAATCGGAATCGGAATGCACCTGCCTGAAACATGACGTCTTGCCCGCCGTCAAGCGGCGCCTCAGTTTCCAAGCGGGCACGGATGTCCTCATACCCGAGCACAACGCGAACAGCGGTTGGCTCTCCATGCGGATCTACGAATGCCGGGTGACGCAGTTCCAACGTATCGAACACCACACGATCTTGCGGCGCACTGGCGTAGGCTTCCTTCAAGGCTTGTTCGAGTGACATGACAAAAGCACGGGACAATATGTAAATGCAACGCGAGAGGCTGCAACGCCATTCCGGCATTGCGCATTACGCATCGCTCATCGTTTCCAATTGACCAGAGACACGCCATAGGTCTCCTGGTATCCGTTCTTCACGGGGAACGGGAAGCAACCACCGAACCTTTCTGAGCTTCAGCCCACCTGGGCCGTTGATGGCCATCAGGAACCATCCCGCATAGCCGTTCAGATCGATGGAGCAAAACCGCTGATAGGCATCGTATTGATCACCATCCAGCACGAAGCTCACGGGTGCATGAATCGGATACACGCGGGAATGTCGCCGGTGTCGGGAACGCCCACTATCCATTTCAGTGCGTTGAAAAGGCGAGATAGGCTGGCGCGAGAATTCCACCAACGGCAAGCCCGCTGGCCAAACTGGAAGGGGCATATACGAAACCTATGCGAGTTGACGGCTCAGCCCGTAACGCCGCTCCAGGGCACGAGGCAAACTGCCCATGCCTGAGTCGATGTCATGGGCGAGCTGGTCCTTTACCTGGCGGAAGATTAGATCGAGGGTCAAGCCGCCGCGAGCGTCAGGCCGCGCACGAACCTGTGGCTGGGACTCCACACCGTGCAGGTTCACTGTCACAGGCGTCGAGGGGCGATAGGAACTGTGTGTCAGTGGTGTGACATGTCCACCGTCCCCACCCGCCAACAGATAGGTGCGGCCGCCCTCGTCATACAACTCCGGACCATTCTCAGCCACTTCATAAAGGCGGCGCGGTAGGGTGGGGCCGCCCATCGCGCGTCTACCAGCCAACTCGGGCATGGCCCAACTGGCCGTAGCCGGAAGCGCTGACCCGAATGCGTTCCTGAACACACTGCCAAGAGCGCTTGCCAACGGCCCGGTTATGCTCTGCCGTACGGAAATGCGCGTCAAGTCTGCAATAATGCTATCGGCGAAGTCGGCAAAGCGAGCCTTGCCCGTGACGACCAACTTGACCAATGCATTCTCAGCCCCTGAGAACGCATTGGCGAATGCGCTGCGCGTTAACTTCGCGACATCGCTGACCAGTTCAGCGTAGTCGTTGAACGCCTGCCTCGCCCCTTCCTTCCAGTCCTTTTCTAGAAGCCGCGCCTTGTTATAGTGGTCGGCCAGCAGTTCCAGACGCCGCTCTAGGCTCTGTTTGAGCACACGAACGCGATCCGCATATGCTTGTGGGGTTATTTCTTTCGCCTCGTTCTGCTCTGCTGCGCGCTGCACTTGACGCTGAAAGTCGCGGTAAATCTGCTGCTGAGCGTGTAGTTGCTCGCGCAGGCGTGGACTGGCCGTCAAACCTGCCAACAGGTCGTTGTAGCGCTGTTGGTCAGCAATGAGCGTCTCCTGCGCCGAGCGCTCCAGCACCTTCAGCTGAACCGCTTCCTTTTTTAGGGTGATCTGGTCCGCCAGTCCGGCGTTCAACTCCAGCTGCTGCCGGAGGGCCTGTTCGTTTGCCAGGACGCTCTTCTCGTCCGCGCTGAGCTGGTCCCTTGCCTTCAGATCCGCGATCCGCTGTTCGAACTTGACCAGTTCCTGGCGCGCTGACGTGATCTTGACGGCACTCTCCAGCTGAGCCCGCAGAGCGGCTTCCTGCTCGCGGGCGCGCTCCAGCTCCCGGACACCAGAAGCAACAGCTCCCTTCGACCCGGCGAACTGCCTCTGGATCTGCGCCACTCGAGCGACGTGCAGCTTCAGCGCCTTTTTATACTCGTCGCTGTTTTGCTTGAACTCGGCTGTTGCCTTTTTGAATGCTGCGTTCTCTGCCTCCATGGACGCCGCCAGTGACGCACCCTTGTGCGACTCCAAATAGCTGTCCAGGTCTTTGCGAGCCTGAATACCGCGCGCGACGGCGCCAGCTTGGTCGGCGCGAGACTTGGCCGCGGCCTTTTGCCACTTGTCCAACTCCTCGAGGCCGGCGATCTCGCCACGCAACTGCTTGATCCGGTCGTCATCGAGGAAGGTGCGAAAGCGCGAGGTCTCCAACGACTGGAGATTCTTCCGTGCCTGGGCCAGCTTCTGTTCAAGCGCCTCTTCACGACCGACCGCCAGCATGGCGTCCCAGGCGCCTTTTGCGACGTCGGTCACCGCTTTCCATGCACGTTCCAGATCGCCAATGTTCTCAACGACCTGCGGGTAGCGCTCCTCCATTGCCTGTGCGTAGGTGTTCAGCGCCAGCCGCGCAGCGTCCTGAGTCCGTCCCTCGGCCTCCAGCGCCTTTACCTGGTCATAGACCGCCAGCGTCAGGAAGTGGTAGCGCTCGTTCAGTTTAGTCAGGGCCTCGGCGGGCGCGTCAGCGATCCGCTCATAGTCCTTGACCATTTCGTCGACGCTGCGCCCAGTGGCGGCCTCGGCCAGTACCGCAGCACGGCCCAGCCCCTCAATCGAGTCGCCGGCGATTTTCCCGGTCTCGACCAGCTTCGTTAGGGCTGCAGCAGCGTTTCCGGTGGTGCCCTGAATATCGGAGATCCGATTCGCCATGGCGGCGAGCTGGCTTTCCGTCACGCCGGCCGCGTTGCCAGTCAGCGTGATAGCGGCAGTAAAGCGCCGCCCTTCCTCTGCCCCTTGTTGGTACGCCACTGCTAAGGCGACTGCACCCGCGGCCGCCGCGGTAAACGGCGTGATGAGGCTGGCGACATAGCCACCCACGGCCTTTATCGCCGGCCCAATGCCGCCGAAGAGGTCTTTCAACTGACCGCCTTGCTGCAGGAGAACGTAGAAGGGAGACTGACCCGTGGACAAGCCTACTGCGATATCTGTCATCTGCATCGGCAGTGAACGCATGGCCGTCCGCATTTCGCCCACCGACAGAGTCGCTGCGGCGGTCTGAGCCTGAGCGGCCTTGGCCGCCTTGCCCATGGCTCCAAGTCCTGTAGCTGCCGCCTTTCCCGCCGTACCAACCTTAACCGTCGCCTGCTCAGCTTTCGCGCCGGCCGCCGCCAGCTTGTCAAGATCAGTAGACGCACCTTTGACTTGGGTGCTGTCCACGCGCAGTACGAGAGAAGCGACTTCATCAGCCATAAGGAACCGTTTACACCCAGCCGGGGGTTACTTCTTGTTCATCATCCGCAGGGCTGCGGACTCCATGACGCGCACACCGTCGAACACATCGATCTCTTGTTCCGGCGGGACGCCAAGCATACGCATGACACCTGCGAGCGCGCCGTAATCGAGGCCAGTTGGCCCGGCGAAGCCAATGCGCCACTGTGAGCCCATCGCTTCGAATACCACCTTGGGCATCACGTTGTCCGGCCACAGTTCGATTACCGCGGCGGGGAAATCGTCTGGTCTCAAGCCAAACTCGGCCAATTGGGCCTTATCCGGCATCGGCCGGTACATTTCCTCCGCCGCGGCTATCAGTTTTTTCGGCGAGCCTGCAGCAACTCGAGGCTGTATGCCTGCACTAATGCCGGTACTGCGCCCTGGTAGTTCTGGATCAAAAGCCCGACTGCCTCGTCGCTGAATTCCATGTCGGGGCCGTCCCAGCCGGCGATCATCTCGTTCACCAGTGCGATATCCTGGGACGCCTCCGACTTGTCGGCCCGCTCCAGGAAGTCCTTCATTTCGTCCCGTGATTTGTGCCTGAACGTGACCTTGATATTGGCTGGCTCTTCACCATGCCGGGGTATTTCCACCGGTACTGTGAAGGTCGGAGCCGGCTGGAGCTTGAATATGATGTTGCTCATCTCTCCCCCTCATCACGCCAGCGGCGCATAACGTGTGAAATCAGACATCATGGAGAACGTGGCGGTGTTCTGCATATTCACGTCCAGCTCCATCGACGGGTCCGAATCGAAGGACGGGTACACCAGGTAGTACAGTTCGTCGTGGTTGGGCAGCTTCGCCCTCAACACAACCGCATCTTTAGCCGCGTCGGCTTCTTTCAACGCCTCATACCATGCCAAGGCGGGGTCGTAGTCCAGCGTCAGAGTGATGAACTTGGCGCTCTTGTAGGTCGGGCGTTGCCGTTGACGACTGTTGCGGTCTTCGACGTACCTCCATTGATAGAACTGCTGTTCACCTCCTGTCTTGGCCACATTGGTGACCTGTGACAGGTCTACCCATGTCGAAACTGGCGTTGCCGTGCCAATACCCTGCCCCTTGGAAAACCGACCGACCTTCGTCGTATCGATCCCCTCCAATGCGAATGTGTTTGATGCTGTGTTGACCGCACGTACAACACGTTCGTTCAGCTCCGGCCAACCGGACTTCATGATCAGGATCGTGCCTGCCTTCGGCGGACTCGTCGCGCTGGCGACGGCAGGATTGGCATTAGTAATTGCAGAAACAGCAACAGCCGCACCCAATCCAGTAGATACCGAGAAGACGGTGCCGTTGGGGAATATTGCGCTGATGATAGTTCCTTAGGGGGCCAACGGCCCCTCATCGAAGCCCAGAGGGCAATAAAAAACCGCCATGTGGCGGGTTCCAGTTGCGCCCTTACGGGCCATCGGCATACGCCGAATCTTCAGATCGAGCATCCTTCGTGCAGCTTCCGCTTCTTGGCTACATACGCCGCATGAGCTACGGCGGGGTCATCGAACAGCCCGACCTCGTGTGCCTTCCCCGCAACCTGTACGCGACTGCGCCATTTCTTCGCACCTCGCTCCCAATACACCCCTAGGTAGCCTGATTTATTGTCAGCCTGGGGGTGTCGCCGGTTCTGCATATTCACGGCCTGAGGGACATCCCGAAGGTTTGCAATGCGATTGTCTGAGCGGTCGCCATTCATATGGTCTATATGCTGTGTGGGCCATGCTCCGTGCATATATAGCCAGGCAAGCCTATGCGCCAGATACCGCTGTCCGTCGATGCCGACGCGCTGATAACCGTTGGCGGTGGCATGGGCCGCATCGTCGCCCACATTGTGACGCTGGGCGAGGCGGACCAACCGCGTGAACTTGCCCGTTTCGGGGTCGTAATGGACAACTGAACGCAGTCGTTCCGCCGTGATTCTGGCTTCGTTCATTGCTATTTCACTCCGGGTAAAACTGGACGTCATATCCCAGGGATATGGGCACGGTGTGATCGGCGTCTCCCGTGGTGGGCTGTCCGTTACTGATCGGTGTGCGCACGCGCACCGCGAGGCCGCCGGACTGCATGACCAGGTTCACGGGGAACAGCGCGTCAAGCTCCGCCGCAACCTGCTCCGCGCTGCGCGACCCGTCGCCGATCGGCATCACCACGTTCACCTGGAACACGCCGCGGTACTGCCGGTGATCGCCGGCGGCGTCCCGGCTGATGGTCGCGGCGGGCATGACATAGGCGCGCAGGTAGACCCCAGCGGCGGGCGGCGTGAACTTCGTGTTCTGCCACGCCACGGGCAGCGCCGGCGTGCGGGCCTTGGCCCAGTCGCTCAGCCGCTTCTCGAAAGCGGCGCGGATCAAATCCTGGCTCATTTGTTGGCGTCCTTTGCCGCCTGGCTCACGTATTGCGGAAACTCCTGCGCGGTCAGCTTGACCATGCCCTGCGGCGCCTGCTTGGACCAGCCGTTTTCCAGCGGGACTGCATACGGCAGCGAGTTGGACAGGTAGGTCACGCCACCCGCGCCGGTGCGCTGGATCTCTGCCACCAGGCGGTTCAGCGTGACCTGGCCACCACGATCAACAGCGAGCGACGTGGCGCGCTGAATGCCAGACGCCGAGAATTGCCAATTGGCCCGAAACCGCCCTTTGTCTACCGGCGACTTCAGAATCACGCCCTCGGCGAGCAGCACCGTGGCCTGGCGCGTCGCGGTGTCGACGTTGCCCTTGGCGCGCGCGACGAACTTACCGAGATCAGCGGTGAAGCTCATGCTTGCCTCAACTGCAGTTCGAACAGCAGCACCAGGCCGGCTGGCGCCAACGTCTTGACCGTCACCACGCGCCAGGTGGCGCCCAGCGCCAGCACTAGGTCGGCCGGCTTGGGCTCGGGCATCGCGCCGCCCGCGGCCAGCTCCGGCGCCAGATACATCTGCTTGTCGCCGGTCTCGATGACGGAGCCGGCCATGTTGGCCAGGCCCGCGGCCTGCGCGGTGTAGTCGAACAGCGCGCCAATGCCGTCGTTGTCCACCGTGGTGGTGGACGCCTGACCAAGATCCGGGTCATACTCGCCCGTCACTATCTGGCGCACAGTCACCGGGCCGCCGAACTCATCCAGCAATTCTTGGGCGGTAGCGGCCATATCGGCATAGTCGAAGGTGGCCATCAGTCGGGCTTCCCTGAAACATTCACGTCCATGATCAGCGTGGCGCGCCAGATCGGCTCATCGGTACCCGCTTCCAGCTTCACCGCCACCAAGCCTGGAATCGGTGCGCCGTCCGCCGTGTACAGCCGGATGCCGCGGCAGTCCTGCAAGCCTGGCGCATCGGTGGGCGTCGGTAGAACCAGGCGAAGGAAGTTGCCCATCTCAGCACCTCACCAGCTTGACCGACGAGCCGTAGGACGACAGCCAGCGGCGCAGCATGGCCGTCACGCCCGCATAGCGCGTCTGGCCGTCGTTGCGCGCGCCGGCGGCGTTGGCGTACTTCGTCGTGATCGGGCCGACGGTCTTCTCGATAGCGGCGCCCACCGTGGTGCCGCTGACGTCCTGCCACAGCGGGCTCTTCAGCGCACGCGCCGCCAGTTCGCAGCAGGCGTTCACGACCTCGCGCGGCACGCCGGTGGCGACCGTGCGCGGCCATTCCAGCGCCTGGATGTCGGTGGCGCGCTCGCCGCGGTAGGTGTATTCGCCATCCAGGTACAGCGTGGCGTTGCGCAGCGCGGCTTCCAGTGCCGCAGCCTCGCCGGCGAAGGCCAGGCCATGGTCGGCTGCATAGGCCTGGCAGTCCGCCACGCTCACGTAGCTGTCCGCGTTCGCCAGGCCGGATCCGTCTTCGACGATCAGGGGCATTGAGGTATCTCCACAGGCTGACGGAAGCCCCCGCGTGAGCAGGGGCGACCGTCAAACGGCGGTCAGGCCTTGGCCGGATCCTTGACCGGGTCCTTGGGCGTCGGCTCGAGTTCCTTCTCCTTGGCGGCCTCGGCCTTGCCCTTCGGCCGGTACTCCGGCTTCAGGGTGACCTTCGGCACGTCCTTGGCGGCCCCCTTGCGGTCCTCGGTGGCGTTGGCATCGACGATGCGCACGCCTGCCTTGGCGGCCTCGGCCTTGACGTCCTGCTCGTAGCGGTAGAACGGGCCCGGCAGGTACCAGATGGGCAGCTTTGCTTTCATGGTGGTCCCTTACTTGGAAGCGTCACCGATGGCGATAACGCCGGCGGTGTGCTTGATATCGGTAGCCACTTTGTCCCAGTTGGTGCCCGTGGCCAACTCGGCGTCGGTCGGCGACTTGCCGCCGGTGGCCTCGTCCCACGTGTAGCCCTTGAGGCCCAGACCAAATGTGTAGTCCGCCTGGAAGGTGGTTTCGATGCGCTCCTTGCCGTTCGAGGTTTCGATGTTGGTGATCAGATCGCCGCCATCAGACACTGTTGCAGCGCCGGCCACCAGACCCAGCACCTTCTGCAGGTTGGGCGTGCCCGTGGCATAGAGCGCCGGCGCGTCAGTTACCACCACAGTCTTGCCCAGGATGTCCACAACAGTGACCGCACCGTACTCGAACAGTTGCTGAGCGTTGACAAGATTCTGGCCGATCAACTTGTGGTAGACCTGGCCGCTCATCACGTTGGCGACGATCAGACCGGAGCTATCGCCGAACTTGGCATGAGCGTCGTTCAGCACCGAGTAGTTCAGTCCGGTCTTGGCCGAAACGTTGACCGTTGCCAAAGCCTGATTACTGATGGCGGCCACTAGCGCGGCAATGGCGGTATTCAGCTGGTCCTGCAAGAGCGCCTCGGCGAAGTGGCGCGAAGCCACCTCGATGCCCTCCGCCGTAGGCTTCTCCAGCCATGTCATTTGCGACGGCTCGTAGCGGATCGGGCCGAAGCCGCCCGCGACCTTCACCGAGCTGTGCTTCAGCTGGGTCAGATCGGTGGGCGAGGCGCTGCCATTGGCAGCATAGCGATCGACACGACGACGGGCGCCGTGGATGGCTTGGTAGAACGATTCCTGGAGGAAGTCGCCTTCGAAGCCGGCCGTGGTCAGCATGATCGCGCCGCGCGAGGCAGCATTGAACTTCTGGATCTGCTGCCCCAGCGTCTCGATGATCGCGGGCATGAAGTACTTGTTAAAAACCTGCATCTGCGAGATAGACATGAATTCTCCTCTATCGTTGTGCGGTATCAGCCCGAAAGCTCGGGGAATTTGGCCTTCAGGGCTGCCACGCGATCCTCGCGCGAGCCGCCCATGTTGCCCGTGCACTTACCGCCACCGTTTCCGCCCTGGCCGCCACCGCCGGTATTCGCGGGTGCAGTAATGAAGTGCTTGCCCTGATCGGTGCTCGCCCATTCCATGACGTGGTCGTCCAGTAGCTTGTCACCGATTACCGCTGCACCGTCCTTGATAGACGTTTGGCTGCGCAGCATTGCTTTGACGGCGTCCATGAAGTGCGGCGCCACGCCGGCCTTGGCCAGCGCGGTCGACAAGCCGCCATCGATCAGGTGCTGGGTCAAGGCGCCCTCCTTTTCGGTCAGGTCCTTGGTCAGCTTTTCGATCTGGCGGGCGCTGTCCTTGGTCGCCTTCTCCAGCTTGCCGGTCAGCTCCTCGACTTGGGTCTGGAGCCGGGCGTGCTCTTCGGGGTCGATCTCGGAGCCCTTGGCTTTCGCCTTCGCCGTGCGCAGCTCGGCGATCAGCTCCTTGTTCTTGGCGCTCAGCGCCTCGGTAGCCTCGGCAGTCACCTCTTCGATCAAGGCTTTGACTTCGGGGTCGTTACGGTCAAGCGGCATGGTGTTGTCCTCTGGACGGTTGCAGGGCACAGCCCCAAATACAAAAGCCCCGCCGACACAGTCGGCAGGGCTAAGAAAGAAAAAAGGCCCGCGCAGTGGCGGGCCGGACGGGAATGGCTCAGATCATTTCAAAACGACGCGCTCACCGCGCACGAAACACAGCGCGCACAGCAGTACCTTCGTTCCGCCCGACCACGAGCGGCCAGACTCGAACACGCCAATGCGGGTCTCAATGACCTCGCGTGCACCACAGCGGTGACACTGGATCATGTCTTTCGGCTTCGGCAGGGCCTTGATCCGCTTCCGGATACGGTCCTTCTCCGTTTCCGCCGGCTTGGGAGCGTCGGGTACGAGGTGGAGAGGCATGCACACTATTTTACGCCGGCCCGGGCAAACGCGGCAGCATCCTTACGCCTCAGCTCGGCCAGCGTGAGATATACGCCTCGGTCGTTGTAGAAACTTTCCAGCTCAACCCCCCCCTTGCGGAACAGCGCGCCGCGGGTCGGACCCAGGATATCGTCCTGGATCGCGGCGGGCTGCCTGCGGAGCCACTCCGCATAGGTCGTTGTCGCCCGCACTTGCTCGCCCTTGCCGCGCGCGCTGTCTCGGTAGTCCTTCGCCGCTCTGGTGCCGATGAGCGGGTCATCTTCCATCCCCTTCAGGATCGGCACTGAGCCGCTGCGGCAACACCAATGTAGCTTGCCAGGGCCAGCGCCCCAAGGGACTCGGTGGCCGATCGGTTTGTGATCAGTCGTGTACTGCAGGCCATCGCGCAGCCGGCACATCTGGCTGGTGCGCGAGTCCAGCGTACTGACCCAGACCAGCGCGCCGATGATGTCGTCGTTGGCCTCGTACCAGCGATCTCGGGCAAGGCCGGCCGTGTGGCTGATTGCAGTGCGCACCACGGCTTCGGCGTTGCGTCGGTCGATCTCCAGCAGACCGTCAGCATAGCCCTTCGCCCGAGTGCCGCGCACGCGCTGCACCACCTGCTGAATGGTCTGTCCCTCCACATAGCCCATGCGCACGGCATCGCGGATTCGGCTGGCGCGCCCTGACTCGAGACCGGCCATCCATTCCCGCAACAGGCGCCCCTGGAATGGTTGAGCCATAGCGCCGACATAGACCTGCCCGGCCGTGACACCGCGCGTGGTGAACTCGATGCCCAGCGATTCGAATAGCTGGCTCTGGTAGCCGACCTCGTAGCCAGCTAGGTCACGCAGATCCTTCTCCAACTCGCCGCGCACCTGCCGGTACGCCTCGGCGTTCAGGTTACGGACGTCCTTCAGCACCGCATCCAAGCGCGCCACCGTAAAGGCGCTGGCTGGCAGACGTTCCATGGCCCGGGCCACCTGCTCGGCCAGGTCGATGTCGACGCGGTTTAGCAAGGCAATAATCCGACGCACCACCCCGTTGCTGTAACGCACCAGGTCGATGGAGTGCCGGACGGTGGCGTCATACAGCTCTGTTTGCAGGCTGGCCATCCTGGCCTCCCAGCGTGCCCAGCGCCGGGCCGGCAGCTTCGATGCGGGCTTGCTCTTCCTCGAATGTCACCCCGTCGTCGATGATGCCGCCGCGGCGCATGTTGTCGTAGAACGTTTCCGGGCTGATCGCCGCGGCCTGCAGCGCGCCCACCAGGGCGGTCAGGTCCTGGGCGGTCAGGCCGACCGGGAAGAACTCAGTGTTCAGCTTCACCTCGACGGTGCCCGAGCCGGCGCCTGCCCACTCGGCGGCCCAGCGGAAGGCCTTGGCCAGCGACCGACCCACGCCCAGGGCGATGCCGCCCAGCACGCTGTTCTCGCCGGCTCGGTGGATCTTGGCCGTCTCGGCCGCCTCGGCGTCGCGCTTCTCCGGTGCCAAAATGCGGGCGCCCAGGGTGGCCATCATGCCCTCCTTGCGCTCCAGGCTGACCTTGATGCTGTCCAGGCCCTGGCCGGAGAACTCCAGGTACTGAGCTCGCGCCTCGGCCTCGGAGAATACCCAAGCCTCGGAAGAGCCGATCTTCAGGGACTGGCCAGCCTGCAACTCATGCCCGGTAACAACCGCCGTGGGCAGCGCCGTGAAGTGCAGCGCGTGCTCGTAGTCGGCCGTGCCACGGTAGTGCGACATGTTCACATCGACCAGGTCGAGTAGCACAGGCTTCTGTGGGTCGATCGCTTCACCGTTGCGCCCTATCAGGACGAAGGGGATGTAAGGCAGCCGCTTGCCGTTCATCATCGGCGTGTACTCGAATGCCGGCGTGTTCAGGTCGGTGCGGTAGATGCGCACACGATAGGCACCGTCCGCCAGGTCGAGCACCCGGTACTGCGTCTTCTCCTCGGCGGTGAACTCGTCCTTCTGCTCGGTGTAGGTCTCGGCCAACACCACCAGCACCAGCTGGTTCACGCCGCTCACCCGGGCCGTGCGCCAGTTGATGATGGCCTCGGCCTTGTAGGTGGCCAGGTAGGGCCGCAGGCCGACCGCCTGGGCCTGGCCCACGGTCATGAACTCGCCGCTGGCCACCGGGTAATCCACCAGCACGCCCACGCGGGTGACGTCGATCACCTCCTTCACCACGTTCTCGATGAACGTGTCTACCGGCGTGCCCGCTAGGTCGGCGTCCTCGATCATCGGCTGCAGCGCCGCCGGCAGCGTCACGGTGGGCTCCTTGCGGAACACCATGCCGATCAGCGCTTCCTCGGTGCGGGCGGTGGCGCCGTAGAACAGCGCGCGGCCCTTGTAGGCGTCGTACTCCTCCTGCTCCTGCCCTGCCAGCTTGGGCAGGTACTTGGTGCCGGCCGCATGCACGGCGTCCTGGCCCTGCAGCGCGGTTCGGCAGCGCTCCCATCGCGGCTGGCTGGCCGTCCAGAGAGGGTGTTTGCTGTCGACGGGCATGATCAGGTTCCTGTGAGTTTGATGCGGCTCATGCCGGTGGGCGTGATCGGGTATCGGTGCACCAGGAAGTAGCCCTGGGCGTCGTTCGGGTGGTCGTGCCCCGTCGACTTGTCCGGCTCCCCGTTCTTGTCGTAGGCCTGCTGCTCCAGCGCCTCGGTCAGCGTCGGGCACCGGTCGGTATTGACCAGCCAGCGCCGGGCGCCTTCGTCGTTGAGCAGCATGCCGTTCACGGCGTTGATTCGGTCCTTCACGGCCGGGTTTCGGCTGTTCACCCGAACGGTGAACCCCGCCTTGCGCAGGATGCTCAAATCCGACTCACTGGCGTTTTTGCTGCTGGTATTCCCGCCGCTGGCGTCGGGGTAGATCGTGACGCCGTGGCCCTTGTCCTTGAAGCGCTCCTTGAGCATGCGGGCCATTTCCGGCGTGTCGCGCACCTTCGTCAACTCTCCCACCGTCAGCGGCAAGCCGGCCCGGATCACGTTGACCGTCGCCGTCATGTTCAGCACGTTGAAGTCCATGCCGATGTGCAGCTCTTCGTGCGGCTCCTCGGCGGCGTCCGTGTGGTGCAGGCGCCGGTCAAAGTTGGGGTACACGCTACCGCTGGTCAGGTTGGTGAACTGGCCACGCAAATACGCCGCGATCAGCTGCGGCGGATAGCTCGCCCGCAGCGACGGGATGTAGTCTTCCGGCAGGTTCTTACCGTTCTCGTAGGTGCTGGCTTGCACCAAGCCGTACAAGGCAACCAGATCGGGCCGCTCGCGCACCTGCTTGACGAACTGCTGGTAGACGAACTTGAACCCCTCGGGCGTCGTCGTGACGTCCACGCCGTTGATCAGGCCGGGCGCGGTGTGGCGCAGGCGAGCAATGATCTTTCGCCAGGCCAGCGCGGCCTTGTCCGTCTTCATGACGTCTAGCTCGTCGATCAGCCCCTTGCCGATCTTGAAGCCCACGATGTCGCCCGGCTTCTCCATCGACCGGCAGATCACCGTGCCGCGGTACTTGCGGCCAGCGAACAGGTGCACCTCCTTGTTCGACTCGTTGATCTTGGCTGCCAGCCCCCAGTCGTGGGCCACCTCCTCGATCGTCGGGTAGAAGATGTCCCGGATCTGTCCGTAGGTCGGCGCGAAGTAGCCAGAGTTGACCCGGGGAAACTCCCAGGCGTGGCGACACAGTCCGGCGCCACCTACCCAGGTCTTGCCGCTGCCGAAGCCGGCGACGAACGCGCGGAACTTGTGCGGCAGCGCCAGGAACCGAGCCTGGGGCTGATTAAGGCTCGGCATCGGGGACGCTCGCGTCCTTGACCTCGATCACGACCTTCACCGGCGGCGGCGCGTTGTCGTCGTTCGTGGAGTCCGGCTTGTCCCGCCAGCTATCCGGCGACCGATTCTTCAGATAGAAGATCATTGCGGTGACGTTTCCGCCCACTGCCGCGTCATACAGCGCAGACGACACATCCGCGATGCCGAGCGCCTTCCCTTTTTTAAGGGCCGCCTGGAGCTGTTCATTGCTCGCCTTGTGGCGGCGTAGAGTGCTGTAGGAAATTCCCAGCGCGGACGCAATCTGCTCTTCGTTCAAGCCCTTAGAGGCCAGCGCCTCTATCTGCCCTAGATCGGGCAGTTCTTTCTTCGGTCGTGCCATAAGCTCGCGGTCCCTCTGGGAGCGACGCCGCAGGCATCGATTCCGCGTTGAAAGTGATTCAGGATGCGCCCATCCGACTTACCCGCCAACGGAGCGAGCTGGGCGTGTGCGGTTCTCGTCTACCAGATCCAGCGACGAGGCCGGGGAGAAAGCCCCGCGCGCTTTGATATCCCGCGCGGGCGCCCGTCTGGCTAGGCGGTGTCCTGGGGCGGTGATTCTTGACAGTCCCGAGCCCGCAAAGCAAAAGCCCCGGCCATCGGCTCGGGGCTTCGTTTCTGACGGACGCACAGCGCCCGCCATGGGCATCGGGTCACGTCCTTAGACGGTAGTCGGTCTGTCTTGGGCTGGATTATGCATAACAACGGCGTAGCGTGCAACAAAATCCTCGAAGTTGCTGACCGCCCGCACCAGCACGTCGTCGTATTCGCGCGATCGAAGGTCCAGCGCGCGACATGTTGCCCGCCAGTACGAGCGCGTCACGTAGTGGGCCCGCAGGATGTCGCGGTGCTGATGCAGCATGCGGTAGACCGAGTTGCGCCAGGCAGCCTCGATGAGACCTGCGTCGCTCTCGTCGAGCTCGCGCATATCTTCCTCGCCTCCCCATGCGCCCTGTCCTGCCCGCTTCGCAAGCCTGCGGCACACCTCGTAGGTAGGCGAGACAGCGTAATGCGGCCGGCTACGCATGACTTCGCCCCAGTTCTCGAGGCGGGCATGGAAGTCTGATGGCAGGCGATCCAGCAGCAGCTTGGGCGTCTTCATCGACCTCGTTCCTCGAAAAGTCGGCACCGCTGGCCTACCTGCATGCCATGACCGCAAGCCAGAATGCGGCGCCCGTCGAATTCGCTCTTGACCAAGCGGATATGCGCGCAGCCAGCGCAACTGCGCAACGGCGGCGGCTCTTGGCGGCGCTCTAGCACCTTGAGCGGGTCGCCGCGCTCGGACCGGCGGGCCCACGTCATGCTGCACGCTCCTGCGCTACCGCCCAGCTCAGAATGGCCAGGGCGTCGGCGTCGTTGTCGGTCTCGGGACGGAATCCGCGGGCCTTCGCCTCAGCGATCATGTCGGCCTTGTCGGCGTTGCCCTTCCCCGTCCAATGCTTCTTGATCGTGCCCACACCCACAGGCAACAGGCGCAGGCGATGGCTGTCGGCGAGCATTTCCACGATGCACAGGAAGGCGCCGTAGGCATGCGCCGCGTCCGTGCCGGTGTGCCGCTTCACATCCTCGTAGGCGATGGCGTGCACCTGGCGCTGGGTGATCACCTCGACCAGGAAGGAACGGGCGCGCAGCCAGCGCTGGCCGGGCGACCAGCTGGCGCGCGGCGTGAACACCTCGGTGCCGTGGGAGGTTCGGCCGTCGCGCCCGCGCACCGCCCAGCCCAGCTTCGTGCCCAGGTCCAGGGCCAGGATGGTGACGTTCGGGCCCAGCTCGGGCACCACCGTAGATCCAGCATTGGCGCGGCGTGGCGCGGCGTCGGGGGCCGTTTCAGCACCACCTCGCGCCCAGGGATCTGCGACGTCCGTGTTAATTTTTTCGAGGTCGAATGTGGGCACGCGCGCGTGGCTGCCCGCCAGCGTCCCCGCCAACGGGTCCAGCGGAACGCCTGCCGGCTGCCCGGCGATCAGGTCAACGTGCGTCATGCGAGGGCTCCAATCATGTCCAGGGGCTGGCGACGCTTGTCGCCGGTGAATTGCAGGCTGTCGGCGTGGCGCCAGAGCTGGATCCGCCCTTCCCATTCGCCGTGCCGATTCTTGTCGCAGATCAGCAACGTGTCAGGGGAGTCGTGCGTGTCGGCGGAGACTTCTCCGTCCTTGCGCAGCTCGGCCTCGGCGATCCGCTCCTTTTTCTTGTTCCGCCAGACGGTCAGCATCTGGTCGACCTGGTCGACGATGGCCCCCGAGCCCTTGGCCGAGAACTTCCCCGGCACCTGGTCCTCGTTCTCGCCCTTCTTAGCGTGGTGGACCAGGTGGATGTGCATCCGCAGGTCGCGCGCCAGCGTGCAGAGCATGTCCACGAAGTCCTTCTGGCCGTTGTAGTCATCCTCGCCCCGCACGCACTTCATCAGGCTGTCGATCACCATGTGACGGACCTTCAGGCGGTCAGCGCAGTACCGAATCACGGCGTACAGCATGGCCGGCGTCACGGTGCCCTGCTGGTCGTACAGCCACAGCCGGTCCCGCGACCAGTCGATGAGGCGGTCGACGGCCTGCACGCCAGGCCGGGCGTTCATCGCCGTTTGACGCAGCATGCGCTTCAGGGTGGCCTGGGGCTTCATTTCGAACGAGGCGATGCACACCCGCTCGCCCTGGGTAGCAAAGCCGATGCAGGCCTGGCCCAGCAGCTCGCTCTTGCCGTGGCCGTTGATGCCCTGCCACAACGTCACCTCGCCCGGCCGGAAGCGCAGCAAGTCGTGCGTCTTGGACCAGGGCAGCTTGGCGCCCGTGATCTGATCCCCGTGCTCAACGGTGCGGACCAGGTCGTCGCGCCACGCCTCGGCGGCCAGCACCTTGGCCTGCGGCTCGGCCTCGGCCATGTAGGCCTGGAAGTCGACGTCGTTGGAACTGATGATCTGGCTCATACCCGAAGCTCCTGTAGGTCGGCGGCCGGATCCCACAGCAGGATCCCCCACTCGCCCGATGCGATCGCCTTAGCGGGCGAGAAGTCGCGGACGCGGCGCAGCAGCTGCATTGCCCTGGAGCGTGACGGCGCAACGATGTGGACGACCAAGCCGACCACGACGCGCAGGTCCAGCGCCGCGGCGTTCTCGTCATCGTGGATGTGGATGTCCGGGAACCCTACCCAGCGCCCGTTCGTCATCTGCCCGAGCTGGGCTTCGGGGTGCGTGAAGCGCCCGCAGGGCTGTTCGGCAGTCAGGCAGGTCAGCCAGACGTCGGTGGGCCGGTAGCCACCCATGCGGGCAGCGATGAGGCTCTGGTGTCCTATCACACTGCCCCCGTCCATGGCTGGTCGCTCCCCAGGGCCCCCTGCAACGCCGCGTCTGCCTTCGGCGGGTAGAACGTGTCCCAGGCATGCAGGATCGACTGGTCCATCATCGTCGCCACGTCGTGGCCAGCAGCTCGCAGCGCGTCCAGCTTTGTCACGGCCAGCTTGCGGGCTGCGTCGGTCATGGGCTTTTTCTTCTTCCGCCGCATTTCCTCGAACTGCCGCCAGGGGTCAGCAGGGATCCAGTCCGGCAGCCTCCAGCCCTCGGCCCCCGGCAGGGGGCTTTGGGGGTTATCTTTTTCTTCTCTACTCTTCTCTTCTCTAGGCGTCACTTTTGCGTCACGCGTTACGTTACGCGTGACGTTACGCGTGACGTCACTTTCTAGCTTCTGACGCTCGCGATAACGCTGCTGTCGAGCGGCTGATTTCGACTTGGGAGACGCGTCCGGATCAACGTTGTGATCCTCAAAAAACCTCGGAAATACAAGGCCTTCCGCAGTGCTGACGACCCAGCCAACGGCCTCCATTGCAGCGCCCATTCCAGGCAGATCGGCAATGTCGTCCAGCACGCTTGTGGTAACGGCGCGACATACAAGATCGGTGCCTTCGGCCTTGCCACGCAGCCGCATGACACCCCATACCGAAACCAGCGCTCCTACCGTTACGTTACGCATAACGTTACGCGTGACGCTCATGTGACGCTGGCAATGTTGATTCACGTAACGCGCGAGTTCGCCGTCTTCGTTCATCAAGATATCGGCCATCACGCAAATTCTTGGATCCCTGTAGAGATCCGTCCGCATCTTGATCCAGTCATTGGCCATTACGCGGCCTCCTTCATCTTGTCGTCGTTCGCGGTCAACTTCGCAGCGCAAACGGGTTCCCACCGCGTGTAGCCCCAGTCCCAGGTGGCACGCTTGTGCTCGCGGTCAAGGCCGCTCTGGTCGTACAGCGTGTGGCAGTGGTAGCAGGCGGGAACGGTGAAACGGTCAGGCACCTTCAGGCCGGTGCCCTTCCCCTGGTTCTGGTGCGCCGGCACGACCGTTGGGTCGCCCTTGTAGCTGCAGCACCCGGCGAATTGCTGGTAGCAGCGCTCGCCGCGGCAAGCGGCCAAGTACTTGGGGTCGTGATAGCCCGGGCGTTTCTTCGGGGCGCGGCGCTTGATGACCGACCTCGACATAGGTGTCGACAACCTCGACATGGGCGTCTTGCGCTGGAGAGGTGTACGGCGCAGCAT

Protein sequences of DBSCAN-SWA_2

>CP020651|3619340:3641709|3627272_3627563_-|AWP85724.1|DBSCAN-SWA
MYRPMPDKAQLAEFGLRPDDFPAAVIELWPDNVMPKVVFEAMGSQWRIGFAGPTGLDYGALAGVMRMLGVPPEQEIDVFDGVRVMESAALRMMNKK
>CP020651|3619340:3641709|3619340_3623297_-|AWP85719.1|DBSCAN-SWA
MPDITIQRDPFRPHLRQETIVAPQGVRLDTVLRREGFIVGRGKSLVRTRTFVVQLNGSWKVQSAWHVRLRKHDVVAVVVLPAGGGGSNPLQVVAMAALAAATAGVGAWAASAYAGAAGVAATSAAALTVGAGAATAVGLVGGMVVNSLFPPARLPGSLQREKASPTYTLSAQGNMARPMEAIPARYGRYRSYLDFAAQPYTEMVNNQTHLYQLFCVGQGRYEIEEIRIEETPIGNFSEVEYEVVEPGGQVTLFPDNVVTSAEVQGIELPAINVEGAGPKGPFAANPPGTLASEIAIDILLPKGLFYAAHDGTLESAGTGVNVYARQIDDSGKPIGTTIVLGRENIVAATLTPQYRTFRYKVEPGRWEISVERNSGHLAERATRMIRDVTWLGLRSYLPSQRTYGNVTMLAVAMRATGNLNQTTARRINIIATRRLRTWDPVQGWSQDLKPTRNPAWAIADACTDREYGRGLPDSRINLAALYRLAKVWDERGDWFDGVFDVSTTFWEAVTQIARAGRALPIYHAGVIDVIRDEPKSVRTQMFTPANIVTRSFSVDYVFPAHDDPDYIIVEFVNERTWKDDEVECAWPGAAKRRPYRLRLVGVTGRAQAWREGMALLARNRDQRRFASFQTELEGAIPGYADLVEISHDVPKWGLSGIVEDYDPRALLLTTSEPLQWWQGQNHYISLRGRDGGPAGPFRVEPGSHEREMRIADLVDGHGLYISTGETEEPTHYTFGPGERRALLAQVMRAVPSEGGLWTLDLVNYAPSVHTAELGGQEPEFASPSLLPIVPLGPIVDGVTVFSAPRPGQQIVSATPASGAYRYEFEASDDGGVHWQPLGMAELPSLEVHLRAGSWQVRVRGVGALSGPWKTWQGNVSASAAPPPRLSALTAVSQVMAIELAWTVPDAPWISSVEIWESSTSNLGDASLMGEFRLPQSRFTRFGLSHGTRIWFWGRIRDEAGQVGPWYPDGQGVPGSASSDAGKILDYLSGQIGPEQLTRDLTQTISGMGRNINTVTAKLDQEREERLNQDGALARRVEDAIAANGASATAVKQTSTALSSLDGRLRATWSVQTQVAQDGKVYAAGMALGAYTNERGRVQTSVYFLADRFAFLNLANGKISTPFVVQNGQTFLNKAFIGTAWIKSAQIESLDAGKIVVGVMSADRINAESLIAKLASFTTAYVKTAHIGVAQVDTLRLASGAVVTGSHSIISKSLGRGGSELATVATGSLYLPYGGSVVVFMQYAQSGGRFPFGRNTIVSIDGEIIPNALSNPPDGAAMITWISDALPGGKTISWSIKARHPVDGTYYIGGRVAVLAIQR
>CP020651|3619340:3641709|3633392_3634445_-|AWP87285.1|DBSCAN-SWA
MRYSNGVVRRIIALLNRVDIDLAEQVARAMERLPASAFTVARLDAVLKDVRNLNAEAYRQVRGELEKDLRDLAGYEVGYQSQLFESLGIEFTTRGVTAGQVYVGAMAQPFQGRLLREWMAGLESGRASRIRDAVRMGYVEGQTIQQVVQRVRGTRAKGYADGLLEIDRRNAEAVVRTAISHTAGLARDRWYEANDDIIGALVWVSTLDSRTSQMCRLRDGLQYTTDHKPIGHRVPWGAGPGKLHWCCRSGSVPILKGMEDDPLIGTRAAKDYRDSARGKGEQVRATTTYAEWLRRQPAAIQDDILGPTRGALFRKGGVELESFYNDRGVYLTLAELRRKDAAAFARAGVK
>CP020651|3619340:3641709|3629619_3630018_-|AWP85729.1|DBSCAN-SWA
MSFTADLGKFVARAKGNVDTATRQATVLLAEGVILKSPVDKGRFRANWQFSASGIQRATSLAVDRGGQVTLNRLVAEIQRTGAGGVTYLSNSLPYAVPLENGWSKQAPQGMVKLTAQEFPQYVSQAAKDANK
>CP020651|3619340:3641709|3632418_3633021_-|AWP85735.1|DBSCAN-SWA
MPLDRNDPEVKALIEEVTAEATEALSAKNKELIAELRTAKAKAKGSEIDPEEHARLQTQVEELTGKLEKATKDSARQIEKLTKDLTEKEGALTQHLIDGGLSTALAKAGVAPHFMDAVKAMLRSQTSIKDGAAVIGDKLLDDHVMEWASTDQGKHFITAPANTGGGGQGGNGGGKCTGNMGGSREDRVAALKAKFPELSG
>CP020651|3619340:3641709|3630611_3631094_-|AWP85732.1|DBSCAN-SWA
MPLIVEDGSGLANADSYVSVADCQAYAADHGLAFAGEAAALEAALRNATLYLDGEYTYRGERATDIQALEWPRTVATGVPREVVNACCELAARALKSPLWQDVSGTTVGAAIEKTVGPITTKYANAAGARNDGQTRYAGVTAMLRRWLSSYGSSVKLVRC
>CP020651|3619340:3641709|3630409_3630610_-|AWP85731.1|DBSCAN-SWA
MGNFLRLVLPTPTDAPGLQDCRGIRLYTADGAPIPGLVAVKLEAGTDEPIWRATLIMDVNVSGKPD
>CP020651|3619340:3641709|3630014_3630410_-|AWP85730.1|DBSCAN-SWA
MATFDYADMAATAQELLDEFGGPVTVRQIVTGEYDPDLGQASTTTVDNDGIGALFDYTAQAAGLANMAGSVIETGDKQMYLAPELAAGGAMPEPKPADLVLALGATWRVVTVKTLAPAGLVLLFELQLRQA
>CP020651|3619340:3641709|3640103_3640475_-|AWP87286.1|DBSCAN-SWA
MIGHQSLIAARMGGYRPTDVWLTCLTAEQPCGRFTHPEAQLGQMTNGRWVGFPDIHIHDDENAAALDLRVVVGLVVHIVAPSRSRAMQLLRRVRDFSPAKAIASGEWGILLWDPAADLQELRV
>CP020651|3619340:3641709|3627580_3627910_-|AWP85725.1|DBSCAN-SWA
MSNIIFKLQPAPTFTVPVEIPRHGEEPANIKVTFRHKSRDEMKDFLERADKSEASQDIALVNEMIAGWDGPDMEFSDEAVGLLIQNYQGAVPALVQAYSLELLQARRKN
>CP020651|3619340:3641709|3628692_3629193_-|AWP85727.1|DBSCAN-SWA
MNEARITAERLRSVVHYDPETGKFTRLVRLAQRHNVGDDAAHATANGYQRVGIDGQRYLAHRLAWLYMHGAWPTQHIDHMNGDRSDNRIANLRDVPQAVNMQNRRHPQADNKSGYLGVYWERGAKKWRSRVQVAGKAHEVGLFDDPAVAHAAYVAKKRKLHEGCSI
>CP020651|3619340:3641709|3637848_3638289_-|AWP85740.1|DBSCAN-SWA
MKTPKLLLDRLPSDFHARLENWGEVMRSRPHYAVSPTYEVCRRLAKRAGQGAWGGEEDMRELDESDAGLIEAAWRNSVYRMLHQHRDILRAHYVTRSYWRATCRALDLRSREYDDVLVRAVSNFEDFVARYAVVMHNPAQDRPTTV
>CP020651|3619340:3641709|3627922_3628438_-|AWP85726.1|tail|DBSCAN-SWA
MKSGWPELNERVVRAVNTASNTFALEGIDTTKVGRFSKGQGIGTATPVSTWVDLSQVTNVAKTGGEQQFYQWRYVEDRNSRQRQRPTYKSAKFITLTLDYDPALAWYEALKEADAAKDAVVLRAKLPNHDELYYLVYPSFDSDPSMELDVNMQNTATFSMMSDFTRYAPLA
>CP020651|3619340:3641709|3638285_3638489_-|AWP85741.1|DBSCAN-SWA
MTWARRSERGDPLKVLERRQEPPPLRSCAGCAHIRLVKSEFDGRRILACGHGMQVGQRCRLFEERGR
>CP020651|3619340:3641709|3633144_3633387_-|AWP87284.1|DBSCAN-SWA
MPLHLVPDAPKPAETEKDRIRKRIKALPKPKDMIQCHRCGAREVIETRIGVFESGRSWSGGTKVLLCALCFVRGERVVLK
>CP020651|3619340:3641709|3637158_3637530_-|AWP85738.1|DBSCAN-SWA
MARPKKELPDLGQIEALASKGLNEEQIASALGISYSTLRRHKASNEQLQAALKKGKALGIADVSSALYDAAVGGNVTAMIFYLKNRSPDSWRDKPDSTNDDNAPPPVKVVIEVKDASVPDAEP
>CP020651|3619340:3641709|3634473_3635892_-|AWP85736.1|DBSCAN-SWA
MPVDSKHPLWTASQPRWERCRTALQGQDAVHAAGTKYLPKLAGQEQEEYDAYKGRALFYGATARTEEALIGMVFRKEPTVTLPAALQPMIEDADLAGTPVDTFIENVVKEVIDVTRVGVLVDYPVASGEFMTVGQAQAVGLRPYLATYKAEAIINWRTARVSGVNQLVLVVLAETYTEQKDEFTAEEKTQYRVLDLADGAYRVRIYRTDLNTPAFEYTPMMNGKRLPYIPFVLIGRNGEAIDPQKPVLLDLVDVNMSHYRGTADYEHALHFTALPTAVVTGHELQAGQSLKIGSSEAWVFSEAEARAQYLEFSGQGLDSIKVSLERKEGMMATLGARILAPEKRDAEAAETAKIHRAGENSVLGGIALGVGRSLAKAFRWAAEWAGAGSGTVEVKLNTEFFPVGLTAQDLTALVGALQAAAISPETFYDNMRRGGIIDDGVTFEEEQARIEAAGPALGTLGGQDGQPANRAV
>CP020651|3619340:3641709|3631423_3632392_-|AWP85734.1|DBSCAN-SWA
MSISQMQVFNKYFMPAIIETLGQQIQKFNAASRGAIMLTTAGFEGDFLQESFYQAIHGARRRVDRYAANGSASPTDLTQLKHSSVKVAGGFGPIRYEPSQMTWLEKPTAEGIEVASRHFAEALLQDQLNTAIAALVAAISNQALATVNVSAKTGLNYSVLNDAHAKFGDSSGLIVANVMSGQVYHKLIGQNLVNAQQLFEYGAVTVVDILGKTVVVTDAPALYATGTPNLQKVLGLVAGAATVSDGGDLITNIETSNGKERIETTFQADYTFGLGLKGYTWDEATGGKSPTDAELATGTNWDKVATDIKHTAGVIAIGDASK
>CP020651|3619340:3641709|3631156_3631414_-|AWP85733.1|DBSCAN-SWA
MKAKLPIWYLPGPFYRYEQDVKAEAAKAGVRIVDANATEDRKGAAKDVPKVTLKPEYRPKGKAEAAKEKELEPTPKDPVKDPAKA
>CP020651|3619340:3641709|3623675_3624209_-|AWP85721.1|DBSCAN-SWA
MSLEQALKEAYASAPQDRVVFDTLELRHPAFVDPHGEPTAVRVVLGYEDIRARLETEAPLDGGQDVMFQAGAFRFRLPGFEEGQVPSLLIAIDGASEQIVDHVEAAVQSRFPIYVTYRPYLSTDLSMPQMNPPITMELNKVTVTGSSVSGTATLSDVHNWAFPHERYVRERFPGLFR
>CP020651|3619340:3641709|3629200_3629623_-|AWP85728.1|DBSCAN-SWA
MSQDLIRAAFEKRLSDWAKARTPALPVAWQNTKFTPPAAGVYLRAYVMPAATISRDAAGDHRQYRGVFQVNVVMPIGDGSRSAEQVAAELDALFPVNLVMQSGGLAVRVRTPISNGQPTTGDADHTVPISLGYDVQFYPE
>CP020651|3619340:3641709|3639165_3640107_-|AWP85743.1|DBSCAN-SWA
MSQIISSNDVDFQAYMAEAEPQAKVLAAEAWRDDLVRTVEHGDQITGAKLPWSKTHDLLRFRPGEVTLWQGINGHGKSELLGQACIGFATQGERVCIASFEMKPQATLKRMLRQTAMNARPGVQAVDRLIDWSRDRLWLYDQQGTVTPAMLYAVIRYCADRLKVRHMVIDSLMKCVRGEDDYNGQKDFVDMLCTLARDLRMHIHLVHHAKKGENEDQVPGKFSAKGSGAIVDQVDQMLTVWRNKKKERIAEAELRKDGEVSADTHDSPDTLLICDKNRHGEWEGRIQLWRHADSLQFTGDKRRQPLDMIGALA
>CP020651|3619340:3641709|3624275_3624635_-|AWP85722.1|DBSCAN-SWA
MPLPVWPAGLPLVEFSRQPISPFQRTEMDSGRSRHRRHSRVYPIHAPVSFVLDGDQYDAYQRFCSIDLNGYAGWFLMAINGPGGLKLRKVRWLLPVPREERIPGDLWRVSGQLETMSDA
>CP020651|3619340:3641709|3641295_3641709_-|AWP85745.1|DBSCAN-SWA
MLRRTPLQRKTPMSRLSTPMSRSVIKRRAPKKRPGYHDPKYLAACRGERCYQQFAGCCSYKGDPTVVPAHQNQGKGTGLKVPDRFTVPACYHCHTLYDQSGLDREHKRATWDWGYTRWEPVCAAKLTANDDKMKEAA
>CP020651|3619340:3641709|3637608_3637836_-|AWP85739.1|DBSCAN-SWA
MPMAGAVRPSETKPRADGRGFCFAGSGLSRITAPGHRLARRAPARDIKARGAFSPASSLDLVDENRTRPARSVGG
>CP020651|3619340:3641709|3638485_3639169_-|AWP85742.1|DBSCAN-SWA
MTHVDLIAGQPAGVPLDPLAGTLAGSHARVPTFDLEKINTDVADPWARGGAETAPDAAPRRANAGSTVVPELGPNVTILALDLGTKLGWAVRGRDGRTSHGTEVFTPRASWSPGQRWLRARSFLVEVITQRQVHAIAYEDVKRHTGTDAAHAYGAFLCIVEMLADSHRLRLLPVGVGTIKKHWTGKGNADKADMIAEAKARGFRPETDNDADALAILSWAVAQERAA
>CP020651|3619340:3641709|3640471_3641296_-|AWP85744.1|DBSCAN-SWA
MANDWIKMRTDLYRDPRICVMADILMNEDGELARYVNQHCQRHMSVTRNVMRNVTVGALVSVWGVMRLRGKAEGTDLVCRAVTTSVLDDIADLPGMGAAMEAVGWVVSTAEGLVFPRFFEDHNVDPDASPKSKSAARQQRYRERQKLESDVTRNVTRNVTRDAKVTPREEKSREEKDNPQSPLPGAEGWRLPDWIPADPWRQFEEMRRKKKKPMTDAARKLAVTKLDALRAAGHDVATMMDQSILHAWDTFYPPKADAALQGALGSDQPWTGAV
>CP020651|3619340:3641709|3624644_3627245_-|AWP85723.1|tail|DBSCAN-SWA
MADEVASLVLRVDSTQVKGASTDLDKLAAAGAKAEQATVKVGTAGKAAATGLGAMGKAAKAAQAQTAAATLSVGEMRTAMRSLPMQMTDIAVGLSTGQSPFYVLLQQGGQLKDLFGGIGPAIKAVGGYVASLITPFTAAAAGAVALAVAYQQGAEEGRRFTAAITLTGNAAGVTESQLAAMANRISDIQGTTGNAAAALTKLVETGKIAGDSIEGLGRAAVLAEAATGRSVDEMVKDYERIADAPAEALTKLNERYHFLTLAVYDQVKALEAEGRTQDAARLALNTYAQAMEERYPQVVENIGDLERAWKAVTDVAKGAWDAMLAVGREEALEQKLAQARKNLQSLETSRFRTFLDDDRIKQLRGEIAGLEELDKWQKAAAKSRADQAGAVARGIQARKDLDSYLESHKGASLAASMEAENAAFKKATAEFKQNSDEYKKALKLHVARVAQIQRQFAGSKGAVASGVRELERAREQEAALRAQLESAVKITSARQELVKFEQRIADLKARDQLSADEKSVLANEQALRQQLELNAGLADQITLKKEAVQLKVLERSAQETLIADQQRYNDLLAGLTASPRLREQLHAQQQIYRDFQRQVQRAAEQNEAKEITPQAYADRVRVLKQSLERRLELLADHYNKARLLEKDWKEGARQAFNDYAELVSDVAKLTRSAFANAFSGAENALVKLVVTGKARFADFADSIIADLTRISVRQSITGPLASALGSVFRNAFGSALPATASWAMPELAGRRAMGGPTLPRRLYEVAENGPELYDEGGRTYLLAGGDGGHVTPLTHSSYRPSTPVTVNLHGVESQPQVRARPDARGGLTLDLIFRQVKDQLAHDIDSGMGSLPRALERRYGLSRQLA
>CP020651|3619340:3641709|3623289_3623679_-|AWP85720.1|DBSCAN-SWA
MTSSDVNRYIGLMWRLGGRGPDAYDCWGLLRECRERYFEGGIPETALGEQARALYAHKMRTGAWKIVTHPQHGDGVMLRAGNDPHVGIYLDLDGGGVLHALEGRGVIFSPMRALFTMGFSQPIFYRIHA
>CP020651|3619340:3641709|3635894_3637172_-|AWP85737.1|terminase|DBSCAN-SWA
MPSLNQPQARFLALPHKFRAFVAGFGSGKTWVGGAGLCRHAWEFPRVNSGYFAPTYGQIRDIFYPTIEEVAHDWGLAAKINESNKEVHLFAGRKYRGTVICRSMEKPGDIVGFKIGKGLIDELDVMKTDKAALAWRKIIARLRHTAPGLINGVDVTTTPEGFKFVYQQFVKQVRERPDLVALYGLVQASTYENGKNLPEDYIPSLRASYPPQLIAAYLRGQFTNLTSGSVYPNFDRRLHHTDAAEEPHEELHIGMDFNVLNMTATVNVIRAGLPLTVGELTKVRDTPEMARMLKERFKDKGHGVTIYPDASGGNTSSKNASESDLSILRKAGFTVRVNSRNPAVKDRINAVNGMLLNDEGARRWLVNTDRCPTLTEALEQQAYDKNGEPDKSTGHDHPNDAQGYFLVHRYPITPTGMSRIKLTGT

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWP85719.1|3619340_3623297_-	hypothetical protein	A0A0B5A1N2	Achromobacter_phage	1.2e-219	41.1
AWP85720.1|3623289_3623679_-	hypothetical protein	A0A0G3EYJ9	Achromobacter_phage	3.3e-34	49.2
AWP85721.1|3623675_3624209_-	hypothetical protein	A0A0B5A6T7	Achromobacter_phage	1.2e-47	56.5
AWP85722.1|3624275_3624635_-	hypothetical protein	NA	NA	NA	NA
AWP85723.1|3624644_3627245_-|tail	phage tail tape measure protein	A0A1V0E821	Vibrio_phage	4.5e-103	36.4
AWP85724.1|3627272_3627563_-	hypothetical protein	A0A2H4JBP7	uncultured_Caudovirales_phage	6.3e-14	41.9
AWP85725.1|3627580_3627910_-	hypothetical protein	A0A2H4J121	uncultured_Caudovirales_phage	3.8e-15	43.1
AWP85726.1|3627922_3628438_-|tail	phage tail protein	A0A1S5R1H0	Pseudomonas_phage	1.2e-23	38.3
AWP85727.1|3628692_3629193_-	HNH endonuclease	A0A1I9SEX5	Klebsiella_phage	7.5e-31	45.1
AWP85728.1|3629200_3629623_-	hypothetical protein	NA	NA	NA	NA
AWP85729.1|3629619_3630018_-	hypothetical protein	A0A088FBW9	Salmonella_phage	2.4e-19	39.4
AWP85730.1|3630014_3630410_-	hypothetical protein	A0A2D2W284	Stenotrophomonas_phage	7.8e-07	35.0
AWP85731.1|3630409_3630610_-	hypothetical protein	NA	NA	NA	NA
AWP85732.1|3630611_3631094_-	hypothetical protein	A0A2H4JE38	uncultured_Caudovirales_phage	2.6e-12	38.5
AWP85733.1|3631156_3631414_-	hypothetical protein	NA	NA	NA	NA
AWP85734.1|3631423_3632392_-	hypothetical protein	R9TJ64	Synechococcus_phage	6.6e-124	71.7
AWP85735.1|3632418_3633021_-	hypothetical protein	R9TF81	Synechococcus_phage	5.5e-28	44.3
AWP87284.1|3633144_3633387_-	hypothetical protein	A0A0H5AUE5	Pseudomonas_phage	1.9e-16	51.9
AWP87285.1|3633392_3634445_-	hypothetical protein	A0A0H5BBX3	Pseudomonas_phage	6.3e-96	50.8
AWP85736.1|3634473_3635892_-	hypothetical protein	R9TF43	Synechococcus_phage	1.2e-97	41.5
AWP85737.1|3635894_3637172_-|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	9.2e-150	64.2
AWP85738.1|3637158_3637530_-	DNA-binding protein	A0A090DCM3	Clostridium_phage	6.2e-06	36.7
AWP85739.1|3637608_3637836_-	hypothetical protein	NA	NA	NA	NA
AWP85740.1|3637848_3638289_-	hypothetical protein	NA	NA	NA	NA
AWP85741.1|3638285_3638489_-	hypothetical protein	NA	NA	NA	NA
AWP85742.1|3638485_3639169_-	hypothetical protein	K4ICN3	Acidithiobacillus_phage	4.9e-33	50.0
AWP85743.1|3639165_3640107_-	hypothetical protein	A0A0U4B0G9	Pseudomonas_phage	8.5e-52	36.5
AWP87286.1|3640103_3640475_-	hypothetical protein	NA	NA	NA	NA
AWP85744.1|3640471_3641296_-	hypothetical protein	R9TJW3	Synechococcus_phage	1.9e-07	45.3
AWP85745.1|3641295_3641709_-	hypothetical protein	A4JX58	Burkholderia_virus	8.1e-15	39.1