CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
CP029676	Staphylococcus aureus strain AR_0216 plasmid unnamed1, complete sequence	0 crisprs	NA	0	0	0
CP029677	Staphylococcus aureus strain AR_0216 plasmid unnamed2, complete sequence	0 crisprs	csa3,WYL	0	0	1
CP029678	Staphylococcus aureus strain AR_0216 chromosome, complete genome	9 crisprs	cas3,DEDDh,DinG,csa3,WYL	8	4	12

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

17994 : 26421

Staphylococcus_phage(37.5%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ92979.1\|17994_18573_+	resolvase, N terminal domain protein	A0A0A7NPV4	Enterobacteria_phage	4.9e-42	51.7
AWQ92976.1\|19242_19917_+\|transposase	transposase IS66 family protein	A0A0N9SKD3	Staphylococcus_phage	6.8e-128	99.6
AWQ92993.1\|20085_20451_-	WYL domain protein	E4ZFP5	Streptococcus_phage	1.9e-63	100.0
AWQ92977.1\|20932_21727_-	aminoglycoside 3'-phosphotransferase	E4ZFP6	Streptococcus_phage	2.3e-154	100.0
AWQ92999.1\|21819_22350_-	acetyltransferase family protein	A0A1B0RXL7	Streptococcus_phage	1.3e-89	97.8
AWQ93002.1\|23122_23797_-	DDE domain protein	A0A0N9SKD3	Staphylococcus_phage	2.6e-127	98.7
AWQ92989.1\|23826_24030_-	bacitracin resistance BacA family protein	NA	NA	NA	NA
AWQ92987.1\|24043_24733_-	ABC-2 transporter family protein	NA	NA	NA	NA
AWQ92990.1\|24773_25694_-	ABC transporter family protein	A0A2H4PQG7	Staphylococcus_phage	1.0e-41	42.2
AWQ92986.1\|25818_26421_-	histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein	Q6XLV6	Feldmannia_irregularis_virus	2.8e-08	29.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP029678

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CRISPR-Cas detection and classification

Crispr_ID: CP029678_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029678_1

432086-432186

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029678_1

>merge|CP029678|1|432086-432186|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>CP029678|1|1|432086-432186|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
CP029678.1\|AWQ94911.1\|435001_435580_+\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
CP029678.1\|AWQ95577.1\|425330_425957_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380196
CP029678.1\|AWQ95311.1\|422805_423069_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238045
CP029678.1\|AWQ94872.1\|424045_424627_+\|histidine-phosphatase-super-family-protein	unknown	unknown	gnl\|CDD\|223483
CP029678.1\|AWQ93781.1\|440030_440567_-\|hypothetical-protein	unknown	unknown	unknown
CP029678.1\|AWQ94378.1\|426029_426287_-\|hypothetical-protein	unknown	unknown	unknown
CP029678.1\|AWQ93743.1\|440959_441664_-\|pemK-like-family-protein	unknown	unknown	gnl\|CDD\|367091
CP029678.1\|AWQ93081.1\|424692_425076_-\|putative-membrane-protein	unknown	unknown	unknown
CP029678.1\|AWQ95084.1\|434081_434489_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378584
CP029678.1\|AWQ93842.1\|429837_431226_-\|L-cystine-uptake-protein-TcyP	unknown	unknown	gnl\|CDD\|224736
CP029678.1\|AWQ93033.1\|429001_429757_+\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
CP029678.1\|AWQ95717.1\|438376_439918_+\|GMP-synthase	unknown	unknown	gnl\|CDD\|234614
CP029678.1\|AWQ95217.1\|432202_433159_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235334
CP029678.1\|AWQ95314.1\|435579_436848_+\|xanthine-permease-family-protein	unknown	unknown	gnl\|CDD\|274468
CP029678.1\|AWQ93232.1\|436885_438352_+\|inosine-5'-monophosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
CP029678.1\|AWQ95153.1\|433276_433939_-\|hypothetical-protein	unknown	unknown	unknown
CP029678.1\|AWQ93282.1\|423368_423620_+\|transglycosylase-associated-family-protein	unknown	unknown	gnl\|CDD\|225170
CP029678.1\|AWQ93873.1\|427940_428510_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
CP029678.1\|AWQ95119.1\|442062_442335_-\|transposase-family-protein	unknown	unknown	gnl\|CDD\|225511
CP029678.1\|AWQ95571.1\|426401_427925_-\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942

Protein	Function_ID	Function_description	E-value
CP029678.1\|AWQ94911.1\|435001_435580_+\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
CP029678.1\|AWQ95577.1\|425330_425957_-\|hypothetical-protein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.67126e-71
CP029678.1\|AWQ95311.1\|422805_423069_-\|hypothetical-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.0037414
CP029678.1\|AWQ95571.1\|426401_427925_-\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
CP029678.1\|AWQ93873.1\|427940_428510_-\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
CP029678.1\|AWQ93743.1\|440959_441664_-\|pemK-like-family-protein	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	9.65175e-08
CP029678.1\|AWQ95084.1\|434081_434489_-\|hypothetical-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.0219e-12
CP029678.1\|AWQ93842.1\|429837_431226_-\|L-cystine-uptake-protein-TcyP	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
CP029678.1\|AWQ93033.1\|429001_429757_+\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	5.03864e-88
CP029678.1\|AWQ95717.1\|438376_439918_+\|GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
CP029678.1\|AWQ95217.1\|432202_433159_-\|hypothetical-protein	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.000748442
CP029678.1\|AWQ95314.1\|435579_436848_+\|xanthine-permease-family-protein	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	2.75897e-170
CP029678.1\|AWQ93232.1\|436885_438352_+\|inosine-5'-monophosphate-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
CP029678.1\|AWQ95119.1\|442062_442335_-\|transposase-family-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.23077e-11
CP029678.1\|AWQ94872.1\|424045_424627_+\|histidine-phosphatase-super-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	7.98269e-49
CP029678.1\|AWQ93282.1\|423368_423620_+\|transglycosylase-associated-family-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.58864e-09

>CP029678.1|AWQ93842.1|429837_431226_-|L-cystine-uptake-protein-TcyP
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH
>CP029678.1|AWQ93033.1|429001_429757_+|NADPH-dependent-oxidoreductase
MSEHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>CP029678.1|AWQ93873.1|427940_428510_-|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>CP029678.1|AWQ95571.1|426401_427925_-|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDDKSKELKDLLTEITDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKKLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMNTGEEHLLNLDGIFVQIGLLPNTSWLNDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>CP029678.1|AWQ94378.1|426029_426287_-|hypothetical-protein
MLKVCTSRKQINMKNDIEKEKYVNEIIMLLRTIPTSKLVQPIMQLFIDKAILNNVQNDALLIEKATHARNHLRLWSLQGHRDIPN
>CP029678.1|AWQ95577.1|425330_425957_-|hypothetical-protein
MKKRLLLSTFLASTLILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>CP029678.1|AWQ93081.1|424692_425076_-|putative-membrane-protein
MKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNIIIMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFTSTIITLAIGGKSVEKNDSP
>CP029678.1|AWQ94872.1|424045_424627_+|histidine-phosphatase-super-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYDKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSRAEAVDLKVENCKPYIIE
>CP029678.1|AWQ93282.1|423368_423620_+|transglycosylase-associated-family-protein
MFGFIGMLIVGGLIGWAAGAIMGKDIPGGILGNIIAGIIGSWVGGKLFGQWGPELGSIYILPALIGSIILIAIVTLILRAMRK
>CP029678.1|AWQ95311.1|422805_423069_-|hypothetical-protein
MNMHILYNLRTKHNLEIDELAQQLNEKYGTKYEAHQIWEWENHHHEPKFKDAMHLADFFDAPYEMFLESKVKEYQKHLEEVDIRMDK
>CP029678.1|AWQ95217.1|432202_433159_-|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKALAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNDNAAETSNKEATVDAEAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>CP029678.1|AWQ95153.1|433276_433939_-|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>CP029678.1|AWQ95084.1|434081_434489_-|hypothetical-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHQEVHENNSAYEEIDITHFAEASKGPKA
>CP029678.1|AWQ94911.1|435001_435580_+|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>CP029678.1|AWQ95314.1|435579_436848_+|xanthine-permease-family-protein
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILLLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>CP029678.1|AWQ93232.1|436885_438352_+|inosine-5'-monophosphate-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>CP029678.1|AWQ95717.1|438376_439918_+|GMP-synthase
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>CP029678.1|AWQ93781.1|440030_440567_-|hypothetical-protein
MHNNNEFNKKLKDFIGSDKRMALVKGYVNEYKLTTVLRALNNSDYTKGTIHTRSIGNLKQIVDNRIIPKNITQNTIFKLSNLTLEVNLYERNTIYHGDFAIYYPVESALIIETDTPRLINHINNNPVQKIFIITTNDWSFNTLELEKIVDETIIYDLKQEDPKQYEILYKNKHGKLPY
>CP029678.1|AWQ93743.1|440959_441664_-|pemK-like-family-protein
MSKNINQANSKLNTSNKKLKQAYSKSDSKNMKVIYMPHWLEFYSIAIHSDVTSNKKRYYKSYSRGTVVYVKLGSNIGSEFSGNHFCVILDNKDNKGKETVTIVPLSSKGNKNYLKLNESVLNLTATDLKKQIIDISSKVQALAQKYREIDIKLSTEDKKLLSNLNQKANELYRVIGVYSKHKGKDTYVNISAITTISKRRISKINDSDPTGTIIISEDDMNEIEKQLKIKFFSN
>CP029678.1|AWQ95119.1|442062_442335_-|transposase-family-protein
MTKERRTFSSEFKLQMVRLYKNGKLKNEIIRKYDLKPSIISNSIKQHQNTGPFNHQDNLKSDEKELIKLRKEVQHLKMEHDVLKQILKLI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP029678_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029678_2

676423-676515

Orphan

Consensus_repeat	Method
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029678_2

>merge|CP029678|2|676423-676515|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTAAGGCACAACTGCATAAAAGCCTCTAATCGCTAAAGATGAAGAGGAACGCAGTTGGATGCTA

>CP029678|2|2|676423-676515|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	AGGCACAACTGCATAAAAGCCTCTAATCG
CTAAAGATGAAGAGGAACGCAGTTGGATGCTA

Protein	Signature genes	Signature genes Name	Protein_function
CP029678.1\|AWQ94314.1\|680262_680769_+\|hypothetical-protein	unknown	unknown	unknown
CP029678.1\|AWQ94453.1\|680930_681647_+\|putative-membrane-protein	unknown	unknown	unknown
CP029678.1\|AWQ94398.1\|684176_684737_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377396
CP029678.1\|AWQ94948.1\|676583_677471_+\|periplasmic-binding-family-protein	unknown	unknown	gnl\|CDD\|238563
CP029678.1\|AWQ94219.1\|670817_671324_+\|ywhD-family-protein	unknown	unknown	gnl\|CDD\|378039
CP029678.1\|AWQ93946.1\|666216_666840_+\|tandem-five-TM-family-protein	unknown	unknown	gnl\|CDD\|335700
CP029678.1\|AWQ93319.1\|675569_676205_+\|hhH-GPD-superbase-excision-DNA-repair-family-protein	unknown	unknown	gnl\|CDD\|225140
CP029678.1\|AWQ93619.1\|673520_675182_+\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
CP029678.1\|AWQ94493.1\|669479_670775_+\|HD-domain-protein	unknown	unknown	gnl\|CDD\|224004
CP029678.1\|AWQ95037.1\|678623_679343_+\|HAD-hydrolase,-IA,-variant-1-family-protein	unknown	unknown	gnl\|CDD\|223943
CP029678.1\|AWQ94469.1\|677582_678569_+\|fecCD-transport-family-protein	unknown	unknown	gnl\|CDD\|376439
CP029678.1\|AWQ95181.1\|681815_682604_+\|alpha/beta-hydrolase-fold-family-protein	unknown	unknown	gnl\|CDD\|223669
CP029678.1\|AWQ94814.1\|671822_672833_+\|alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|181842
CP029678.1\|AWQ95147.1\|673107_673524_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226896
CP029678.1\|AWQ93347.1\|684944_685298_-\|integrase-core-domain-protein	unknown	unknown	gnl\|CDD\|225382
CP029678.1\|AWQ94210.1\|668963_669440_+\|acetyltransferase-family-protein	unknown	unknown	gnl\|CDD\|366181
CP029678.1\|AWQ93495.1\|679326_680127_+\|alpha/beta-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223669
CP029678.1\|AWQ93627.1\|682854_683229_-\|transcriptional-regulator-SarA	unknown	unknown	gnl\|CDD\|130944
CP029678.1\|AWQ95554.1\|668258_668795_+\|putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-YwqN	unknown	unknown	gnl\|CDD\|223728
CP029678.1\|AWQ93395.1\|667109_668048_+\|protein-IolS	unknown	unknown	gnl\|CDD\|381309

Protein	Function_ID	Function_description	E-value
CP029678.1\|AWQ93347.1\|684944_685298_-\|integrase-core-domain-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	4.7431e-37
CP029678.1\|AWQ94398.1\|684176_684737_-\|hypothetical-protein	gnl\|CDD\|377396	pfam04657, DMT_YdcZ, Putative inner membrane exporter, YdcZ. DMT_YdcZ is a family of putative inner membrane exporters from both Gram-positive and Gram-negative bacteria.	3.72334e-33
CP029678.1\|AWQ94948.1\|676583_677471_+\|periplasmic-binding-family-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	8.54601e-73
CP029678.1\|AWQ94219.1\|670817_671324_+\|ywhD-family-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	1.08203e-97
CP029678.1\|AWQ93946.1\|666216_666840_+\|tandem-five-TM-family-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	2.9419e-60
CP029678.1\|AWQ93319.1\|675569_676205_+\|hhH-GPD-superbase-excision-DNA-repair-family-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	3.98158e-90
CP029678.1\|AWQ93619.1\|673520_675182_+\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
CP029678.1\|AWQ94493.1\|669479_670775_+\|HD-domain-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
CP029678.1\|AWQ95037.1\|678623_679343_+\|HAD-hydrolase,-IA,-variant-1-family-protein	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
CP029678.1\|AWQ94469.1\|677582_678569_+\|fecCD-transport-family-protein	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	1.17074e-49
CP029678.1\|AWQ95181.1\|681815_682604_+\|alpha/beta-hydrolase-fold-family-protein	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.55978e-34
CP029678.1\|AWQ94814.1\|671822_672833_+\|alcohol-dehydrogenase	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
CP029678.1\|AWQ95147.1\|673107_673524_+\|hypothetical-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	2.62525e-58
CP029678.1\|AWQ94210.1\|668963_669440_+\|acetyltransferase-family-protein	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
CP029678.1\|AWQ93495.1\|679326_680127_+\|alpha/beta-hydrolase-family-protein	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	7.17592e-26
CP029678.1\|AWQ93627.1\|682854_683229_-\|transcriptional-regulator-SarA	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
CP029678.1\|AWQ95554.1\|668258_668795_+\|putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-YwqN	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
CP029678.1\|AWQ93395.1\|667109_668048_+\|protein-IolS	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	7.3194e-168

>CP029678.1|AWQ93319.1|675569_676205_+|hhH-GPD-superbase-excision-DNA-repair-family-protein
MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>CP029678.1|AWQ93619.1|673520_675182_+|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>CP029678.1|AWQ95147.1|673107_673524_+|hypothetical-protein
MDKKVSIQTKQVLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>CP029678.1|AWQ94814.1|671822_672833_+|alcohol-dehydrogenase
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>CP029678.1|AWQ94219.1|670817_671324_+|ywhD-family-protein
MSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>CP029678.1|AWQ94493.1|669479_670775_+|HD-domain-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>CP029678.1|AWQ94210.1|668963_669440_+|acetyltransferase-family-protein
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>CP029678.1|AWQ95554.1|668258_668795_+|putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-YwqN
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>CP029678.1|AWQ93395.1|667109_668048_+|protein-IolS
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDNNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVVENIKAADIVLSDDEIQYIDELFPIED
>CP029678.1|AWQ93946.1|666216_666840_+|tandem-five-TM-family-protein
MLCESKIINKNPKYRIIKYNDEYLMVDIISTWISLFFPFINWFIPKEYVKISREEFENLNIVKPAKKNVFWPVAGSSALLGVALRKYTHLLDIQLDKKLVIAICCITFIGILIFYVRLIKKSSLNIYNTKNKRSKIFLIPTLKNVCFTLFGYILFGGLTMLFLDALLSMSYQNIIVYFVWIAVIMGFFLVNIALIIDKNIHVILKNQ
>CP029678.1|AWQ94948.1|676583_677471_+|periplasmic-binding-family-protein
MKKSLIAFILIFMLVLSGCGMKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>CP029678.1|AWQ94469.1|677582_678569_+|fecCD-transport-family-protein
MNVIIDERKENAMTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVTGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>CP029678.1|AWQ95037.1|678623_679343_+|HAD-hydrolase,-IA,-variant-1-family-protein
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>CP029678.1|AWQ93495.1|679326_680127_+|alpha/beta-hydrolase-family-protein
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLTLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTAAFINKHHDEKHV
>CP029678.1|AWQ94314.1|680262_680769_+|hypothetical-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>CP029678.1|AWQ94453.1|680930_681647_+|putative-membrane-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>CP029678.1|AWQ95181.1|681815_682604_+|alpha/beta-hydrolase-fold-family-protein
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLKFLKSVS
>CP029678.1|AWQ93627.1|682854_683229_-|transcriptional-regulator-SarA
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>CP029678.1|AWQ94398.1|684176_684737_-|hypothetical-protein
MTHCHLIKAIGVLLLIVGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSIALLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>CP029678.1|AWQ93347.1|684944_685298_-|integrase-core-domain-protein
MKPLLPKSITMDRGKEFALFEEIEDELNCSIYFSDLGCPYQRGSIENANGLLRQYYPKGTDFANITQKSLDEAVKQINARPRMIFDYKSSEEMLKYHVSTQNCEPILNDCVRHEPVN

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Crispr_ID: CP029678_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029678_3

852233-852318

Unclear

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029678_3

>merge|CP029678|3|852233-852318|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>CP029678|3|3|852233-852318|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	CCGCCAGCTTCTGTGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
CP029678.1\|AWQ94395.1\|854763_855708_+\|sporulation-Regulator-WhiA-C-terminal-domain-protein	unknown	unknown	gnl\|CDD\|273194
CP029678.1\|AWQ93187.1\|841145_841382_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227234
CP029678.1\|AWQ94829.1\|849140_849422_+\|bacterial-transferase-hexapeptide-family-protein	unknown	unknown	gnl\|CDD\|100047
CP029678.1\|AWQ93258.1\|840498_841149_+\|HD-containing-hydrolase-like-enzyme-family-protein	unknown	unknown	gnl\|CDD\|378993
CP029678.1\|AWQ93360.1\|862319_863510_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
CP029678.1\|AWQ93425.1\|861170_862181_+\|glyceraldehyde-3-phosphate-dehydrogenase,-type-I	unknown	unknown	gnl\|CDD\|273675
CP029678.1\|AWQ95159.1\|853658_854654_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|211689
CP029678.1\|AWQ95693.1\|848089_848929_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
CP029678.1\|AWQ95561.1\|841650_843636_+\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
CP029678.1\|AWQ95303.1\|843643_846490_+\|excinuclease-ABC-subunit-A	unknown	unknown	gnl\|CDD\|234734
CP029678.1\|AWQ95367.1\|863631_864393_+\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
CP029678.1\|AWQ94486.1\|839485_840325_+\|staphyloxanthin-biosynthesis-protein,-putative	unknown	unknown	gnl\|CDD\|226451
CP029678.1\|AWQ95723.1\|857111_858014_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|224015
CP029678.1\|AWQ93067.1\|860104_861118_+\|glycolytic-operon-regulator	unknown	unknown	gnl\|CDD\|225263
CP029678.1\|AWQ95532.1\|856281_856869_+\|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
CP029678.1\|AWQ95415.1\|849429_850869_+\|tetratricopeptide-repeat-family-protein	unknown	unknown	gnl\|CDD\|276808
CP029678.1\|AWQ94824.1\|847151_848084_+\|HPr(Ser)-kinase/phosphatase	unknown	unknown	gnl\|CDD\|235459
CP029678.1\|AWQ95408.1\|852750_853662_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224574
CP029678.1\|AWQ93703.1\|858715_859345_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234750
CP029678.1\|AWQ93719.1\|850935_851871_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540

Protein	Function_ID	Function_description	E-value
CP029678.1\|AWQ94395.1\|854763_855708_+\|sporulation-Regulator-WhiA-C-terminal-domain-protein	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	2.25668e-152
CP029678.1\|AWQ93187.1\|841145_841382_+\|hypothetical-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
CP029678.1\|AWQ94829.1\|849140_849422_+\|bacterial-transferase-hexapeptide-family-protein	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.13458e-26
CP029678.1\|AWQ93258.1\|840498_841149_+\|HD-containing-hydrolase-like-enzyme-family-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
CP029678.1\|AWQ93360.1\|862319_863510_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
CP029678.1\|AWQ93425.1\|861170_862181_+\|glyceraldehyde-3-phosphate-dehydrogenase,-type-I	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
CP029678.1\|AWQ95159.1\|853658_854654_+\|hypothetical-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
CP029678.1\|AWQ95693.1\|848089_848929_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.39921e-119
CP029678.1\|AWQ95561.1\|841650_843636_+\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP029678.1\|AWQ95303.1\|843643_846490_+\|excinuclease-ABC-subunit-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP029678.1\|AWQ95367.1\|863631_864393_+\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.84083e-146
CP029678.1\|AWQ94486.1\|839485_840325_+\|staphyloxanthin-biosynthesis-protein,-putative	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	2.23913e-42
CP029678.1\|AWQ95723.1\|857111_858014_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	4.94096e-153
CP029678.1\|AWQ93067.1\|860104_861118_+\|glycolytic-operon-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92
CP029678.1\|AWQ95532.1\|856281_856869_+\|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
CP029678.1\|AWQ95415.1\|849429_850869_+\|tetratricopeptide-repeat-family-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.28078e-06
CP029678.1\|AWQ94824.1\|847151_848084_+\|HPr(Ser)-kinase/phosphatase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
CP029678.1\|AWQ95408.1\|852750_853662_+\|hypothetical-protein	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
CP029678.1\|AWQ93703.1\|858715_859345_+\|hypothetical-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.85535e-05
CP029678.1\|AWQ93719.1\|850935_851871_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154

>CP029678.1|AWQ93719.1|850935_851871_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>CP029678.1|AWQ95415.1|849429_850869_+|tetratricopeptide-repeat-family-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDMEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVSENDVMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP029678.1|AWQ94829.1|849140_849422_+|bacterial-transferase-hexapeptide-family-protein
MLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP029678.1|AWQ95693.1|848089_848929_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGSVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>CP029678.1|AWQ94824.1|847151_848084_+|HPr(Ser)-kinase/phosphatase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>CP029678.1|AWQ95303.1|843643_846490_+|excinuclease-ABC-subunit-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEHDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>CP029678.1|AWQ95561.1|841650_843636_+|excinuclease-ABC-subunit-B
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>CP029678.1|AWQ93187.1|841145_841382_+|hypothetical-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>CP029678.1|AWQ93258.1|840498_841149_+|HD-containing-hydrolase-like-enzyme-family-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>CP029678.1|AWQ94486.1|839485_840325_+|staphyloxanthin-biosynthesis-protein,-putative
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVTKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>CP029678.1|AWQ95408.1|852750_853662_+|hypothetical-protein
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>CP029678.1|AWQ95159.1|853658_854654_+|hypothetical-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>CP029678.1|AWQ94395.1|854763_855708_+|sporulation-Regulator-WhiA-C-terminal-domain-protein
MSFASEMKNELTRIDVEEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>CP029678.1|AWQ95532.1|856281_856869_+|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>CP029678.1|AWQ95723.1|857111_858014_-|NAD-dependent-epimerase/dehydratase-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKALFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>CP029678.1|AWQ93703.1|858715_859345_+|hypothetical-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDKASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>CP029678.1|AWQ93067.1|860104_861118_+|glycolytic-operon-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>CP029678.1|AWQ93425.1|861170_862181_+|glyceraldehyde-3-phosphate-dehydrogenase,-type-I
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>CP029678.1|AWQ93360.1|862319_863510_+|phosphoglycerate-kinase
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>CP029678.1|AWQ95367.1|863631_864393_+|triose-phosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK

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Crispr_ID: CP029678_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029678_4

895562-895643

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029678_4

>merge|CP029678|4|895562-895643|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>CP029678|4|4|895562-895643|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP029678.1\|AWQ94124.1\|896199_896586_+\|toprim-domain-protein	unknown	unknown	gnl\|CDD\|224572
CP029678.1\|AWQ95502.1\|896578_896875_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
CP029678.1\|AWQ95480.1\|898184_898838_+\|methionine-import-system-permease-protein-MetP	unknown	unknown	gnl\|CDD\|224922
CP029678.1\|AWQ94059.1\|890984_891407_-\|peroxiredoxin,-Ohr-subfamily-protein	unknown	unknown	gnl\|CDD\|274649
CP029678.1\|AWQ94938.1\|891554_892271_+\|3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
CP029678.1\|AWQ93778.1\|898855_899677_+\|NLPA-lipofamily-protein	unknown	unknown	gnl\|CDD\|224381
CP029678.1\|AWQ95683.1\|901879_902608_-\|toxin-beta-grasp-domain-protein	unknown	unknown	gnl\|CDD\|280949
CP029678.1\|AWQ95339.1\|902624_903083_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368753
CP029678.1\|AWQ94662.1\|893506_893863_+\|transcriptional-regulator,-Spx/MgsR-family-protein	unknown	unknown	gnl\|CDD\|239334
CP029678.1\|AWQ93049.1\|897124_898150_+\|methionine-import-ATP-binding-protein-MetN-2	unknown	unknown	gnl\|CDD\|224058
CP029678.1\|AWQ94458.1\|901127_901856_-\|toxin-beta-grasp-domain-protein	unknown	unknown	gnl\|CDD\|280949
CP029678.1\|AWQ95310.1\|894579_895458_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226395
CP029678.1\|AWQ93534.1\|893042_893363_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
CP029678.1\|AWQ94807.1\|889319_889937_-\|lysE-type-translocator-family-protein	unknown	unknown	gnl\|CDD\|224198
CP029678.1\|AWQ94670.1\|899819_901040_-\|phage-integrase-family-protein	unknown	unknown	gnl\|CDD\|271189
CP029678.1\|AWQ93815.1\|894020_894401_+\|glycine-cleavage-system-H-protein	unknown	unknown	gnl\|CDD\|234918
CP029678.1\|AWQ95133.1\|894464_894578_+\|hypothetical-protein	unknown	unknown	unknown
CP029678.1\|AWQ95243.1\|892353_892893_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|380312
CP029678.1\|AWQ93989.1\|903094_903427_-\|helix-turn-helix-family-protein	unknown	unknown	gnl\|CDD\|197775
CP029678.1\|AWQ95493.1\|890091_890586_-\|acetyltransferase-domain-protein	unknown	unknown	gnl\|CDD\|372596

Protein	Function_ID	Function_description	E-value
CP029678.1\|AWQ94124.1\|896199_896586_+\|toprim-domain-protein	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
CP029678.1\|AWQ95502.1\|896578_896875_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
CP029678.1\|AWQ95480.1\|898184_898838_+\|methionine-import-system-permease-protein-MetP	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	1.0876e-98
CP029678.1\|AWQ93534.1\|893042_893363_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.70086e-24
CP029678.1\|AWQ94938.1\|891554_892271_+\|3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.26721e-148
CP029678.1\|AWQ93778.1\|898855_899677_+\|NLPA-lipofamily-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112
CP029678.1\|AWQ95683.1\|901879_902608_-\|toxin-beta-grasp-domain-protein	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	1.46097e-28
CP029678.1\|AWQ94662.1\|893506_893863_+\|transcriptional-regulator,-Spx/MgsR-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
CP029678.1\|AWQ93049.1\|897124_898150_+\|methionine-import-ATP-binding-protein-MetN-2	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
CP029678.1\|AWQ94458.1\|901127_901856_-\|toxin-beta-grasp-domain-protein	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	1.03678e-24
CP029678.1\|AWQ95310.1\|894579_895458_+\|hypothetical-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	9.06932e-75
CP029678.1\|AWQ94059.1\|890984_891407_-\|peroxiredoxin,-Ohr-subfamily-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
CP029678.1\|AWQ94807.1\|889319_889937_-\|lysE-type-translocator-family-protein	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	9.12336e-62
CP029678.1\|AWQ94670.1\|899819_901040_-\|phage-integrase-family-protein	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	9.89414e-38
CP029678.1\|AWQ93815.1\|894020_894401_+\|glycine-cleavage-system-H-protein	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	2.81086e-68
CP029678.1\|AWQ95339.1\|902624_903083_-\|hypothetical-protein	gnl\|CDD\|368753	pfam06114, Peptidase_M78, IrrE N-terminal-like domain. This entry includes the catalytic domain of the protein ImmA, which is a metallopeptidase containing an HEXXH zinc-binding motif from peptidase family M78. ImmA is encoded on a conjugative transposon. Conjugating bacteria are able to transfer conjugative transposons that can, for example, confer resistance to antibiotics. The transposon is integrated into the chromosome, but during conjugation excises itself and then moves to the recipient bacterium and re-integrate into its chromosome. Typically a conjugative tranposon encodes only the proteins required for this activity and the proteins that regulate it. During exponential growth, the ICEBs1 transposon of Bacillus subtilis is inactivated by the immunity repressor protein ImmR, which is encoded by the transposon and represses the genes for excision and transfer. Cleavage of ImmR relaxes repression and allows transfer of the transposon. ImmA has been shown to be essential for the cleavage of ImmR. This domain is also found in in metalloprotease IrrE, a central regulator of DNA damage repair in Deinococcaceae, HTH-type transcriptional regulators RamB and PrpC.	0.00223487
CP029678.1\|AWQ95243.1\|892353_892893_+\|nitroreductase-family-protein	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	1.47647e-49
CP029678.1\|AWQ93989.1\|903094_903427_-\|helix-turn-helix-family-protein	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	6.56309e-09
CP029678.1\|AWQ95493.1\|890091_890586_-\|acetyltransferase-domain-protein	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47

>CP029678.1|AWQ95310.1|894579_895458_+|hypothetical-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLNQSKIGGMPFLKYFKDIPLDENNVPMVLLAQINLDDLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>CP029678.1|AWQ95133.1|894464_894578_+|hypothetical-protein
MKEKLLGTIIWSIATFYYSRMMEIMNLAILKIKIGGS
>CP029678.1|AWQ93815.1|894020_894401_+|glycine-cleavage-system-H-protein
MAVPNELKYSKEHEWVKVEGNVAIIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
>CP029678.1|AWQ94662.1|893506_893863_+|transcriptional-regulator,-Spx/MgsR-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>CP029678.1|AWQ93534.1|893042_893363_-|thioredoxin-family-protein
MQSIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>CP029678.1|AWQ95243.1|892353_892893_+|nitroreductase-family-protein
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEGDMPKAPRKNRNLITLY
>CP029678.1|AWQ94938.1|891554_892271_+|3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGVPQAPGQIDVTDLKAQVTLY
>CP029678.1|AWQ94059.1|890984_891407_-|peroxiredoxin,-Ohr-subfamily-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>CP029678.1|AWQ95493.1|890091_890586_-|acetyltransferase-domain-protein
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>CP029678.1|AWQ94807.1|889319_889937_-|lysE-type-translocator-family-protein
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGETQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF
>CP029678.1|AWQ94124.1|896199_896586_+|toprim-domain-protein
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>CP029678.1|AWQ95502.1|896578_896875_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>CP029678.1|AWQ93049.1|897124_898150_+|methionine-import-ATP-binding-protein-MetN-2
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>CP029678.1|AWQ95480.1|898184_898838_+|methionine-import-system-permease-protein-MetP
MPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>CP029678.1|AWQ93778.1|898855_899677_+|NLPA-lipofamily-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>CP029678.1|AWQ94670.1|899819_901040_-|phage-integrase-family-protein
MWLEKFKNKNKETKYRYYEKYKDPLTAKWRRVSVVLNKNGKQSQKEAQRLLNERIEEKLNDKKPTTLKSLTFHVACDEWFQNYIKTSGSKRTTIKTKLSKLNTLKKFVDEDILINKITLSYAQQVFDEMDSKGYVYQVNKDALSIFKNVFEYTRRIYKLQDLEFLKDITLNKRIKSYDEVKAKRNKYLELNEIESIIKDINTKAQKMHSGIHKRFYLFVALMTEFQALNGMRIGEMLAIQNEDIDFDNKSLNINGTIHWFHDESGGFGVKDTTKTESSYRTIGLSSRSCEILKKAILENKKDSKWNDGYLNRNFVFTNHKGNPMQTERFNKILREAAKDVGIDKEVSSHILRHSHISLLSQQGVSLKAIMDRVGHSDHRTTLSIYSHVTEQMDKDMMNKLEQVKLG
>CP029678.1|AWQ94458.1|901127_901856_-|toxin-beta-grasp-domain-protein
MKKLIVIILINIITLSVSNSASAQGDIGIDNLRNFYTKKDFVDLKDVKDNDTPIANQLQFSNVSYDLISESKDFNKFSNFKGKKLDVFGISYNGQCNNKYIYGGVTATNEYLDKPRNIPINIWINGNHKTISTNKVSTNKKFVTAQEIDVKLRKYLQEEYNIYGHNGTKKGEEYGHKSKFYSGFNIGKVTFHLNNNDTFSYDLFYTGDDGLPKSFLKIYEDNKTVESEKFHLDVDISYKETI
>CP029678.1|AWQ95683.1|901879_902608_-|toxin-beta-grasp-domain-protein
MNKIFRVLTVSLFFFTFLIKNNLAYADVGVINLRNFYTNYQPETLQGVSSGNFSTSHQLEYIDGKYTLYSQFHNEYEAKRLKDHKVDIFGISYSGLCNTKYMYGGITLANQNLDKPRNIPINLWVNGKQNTISTDEVSTQKKEVTAQEIDIKLRKYLQNEYNIYGFNKTKKGQEYGYQSKFNSGFNKGKITFHLNNETSFTYDLFYTGTGQAESFLKIYNDNKTIDAENFHLDVEISYEKTE
>CP029678.1|AWQ95339.1|902624_903083_-|hypothetical-protein
MYLYEKMVIENKEIPIDDGKSLGNFEGLYDNGVILINKNLSETRKAEVLYEELAHHKLTYGNILDQSKWINRKFENYARRHGFISAVPLREIVEAYNYGVRNLYELSEYLQLSEKYILEAIEQYKKIYGIGTHYGEYSITFEPLRVFKYKEI
>CP029678.1|AWQ93989.1|903094_903427_-|helix-turn-helix-family-protein
MRTNDEIITIIKTSMKEQNMSLSELARRVGVAKSAVSRYLNLTREFPLNRAEDFAKVLGIKTEYLLGFAEREESTKQDTIAAHLDGDFTEEELIEIRKYAELVRKAHRNQ

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Crispr_ID: CP029678_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029678_5

1002131-1002413

Orphan

Consensus_repeat	Method
AAAGNCAGCTNNNNANANNNTGCAAGTTGG	CRT

4 spacers

The CRISPR arrays of CP029678_5

>merge|CP029678|5|1002131-1002413|CRT
AAAGTCAGCTTACAATAGTGTGCAAGTTGGCGGGGCCCCAACACAGAGGCTGGCGGAAAGTCAGCTTACAATAGTGTGCAAGTTGGGGTGGAGCCCCGACACAGAGAAATTAGCTCCTCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGCGAAAAGTCAGCTTACAATAGTGTGCAAGTTGGGGTGGGACGACGAAATAAATTTTGCGAAAATATCATTTCTGTCCCACTCCCAAAAAGACAGCAGTAGGATAATTTCAATTTGG

>CP029678|5|1|1002131-1002413|CRT
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	CGGGGCCCCAACACAGAGGCTGGCGG
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	GGTGGAGCCCCGACACAGAGAAATTAGC
TCCTCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACACAGAAGCTGGCGA
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	GGTGGGACGACGAAATAAATTTTGCGAAAATATCATTTCTGTCCCACTCCCAA
AAAGACAGCAGTAGGATAATTTCAATTTGG

Protein	Signature genes	Signature genes Name	Protein_function
CP029678.1\|AWQ93428.1\|995806_996190_-\|kinase-associated-B-family-protein	unknown	unknown	gnl\|CDD\|378054
CP029678.1\|AWQ94907.1\|1017385_1018288_+\|fumarylacetoacetate-(FAA)-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
CP029678.1\|AWQ95722.1\|1006578_1007910_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
CP029678.1\|AWQ94435.1\|992849_993278_-\|na(+)/H(+)-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
CP029678.1\|AWQ95250.1\|997262_997640_+\|S1-RNA-binding-domain-protein	unknown	unknown	gnl\|CDD\|224023
CP029678.1\|AWQ93550.1\|1013566_1017220_+\|helicase-exonuclease-AddAB,-AddA-subunit	unknown	unknown	gnl\|CDD\|274299
CP029678.1\|AWQ95741.1\|1002482_1003412_-\|glycerophosphoryl-diester-phosphodiesterase-family-protein	unknown	unknown	gnl\|CDD\|176543
CP029678.1\|AWQ93806.1\|1009354_1009930_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
CP029678.1\|AWQ93808.1\|991019_992516_-\|na(+)/H(+)-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
CP029678.1\|AWQ94883.1\|1008234_1008810_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223475
CP029678.1\|AWQ95254.1\|993270_995676_-\|na(+)/H(+)-antiporter-subunit-A1	unknown	unknown	gnl\|CDD\|237155
CP029678.1\|AWQ94895.1\|1003653_1005033_-\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
CP029678.1\|AWQ93669.1\|1005022_1006228_-\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
CP029678.1\|AWQ95756.1\|1010089_1013566_+\|helicase-exonuclease-AddAB,-AddB-subunit	unknown	unknown	gnl\|CDD\|213736
CP029678.1\|AWQ94484.1\|998001_999129_+\|flavin-oxidoreductase-/-NADH-oxidase-family-protein	unknown	unknown	gnl\|CDD\|240086
CP029678.1\|AWQ94372.1\|996253_996847_+\|cyclophilin-type-peptidyl-prolyl-cis-trans-isomerase/CLD-family-protein	unknown	unknown	gnl\|CDD\|238908
CP029678.1\|AWQ94415.1\|992508_992763_-\|na(+)/H(+)-antiporter-subunit-C	unknown	unknown	gnl\|CDD\|181497
CP029678.1\|AWQ93519.1\|999436_1000627_+\|ornithine--oxo-acid-transaminase	unknown	unknown	gnl\|CDD\|179736
CP029678.1\|AWQ94973.1\|1008814_1009339_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
CP029678.1\|AWQ94302.1\|1000735_1001980_+\|NAD-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|223411

Protein	Function_ID	Function_description	E-value
CP029678.1\|AWQ93428.1\|995806_996190_-\|kinase-associated-B-family-protein	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	1.89892e-52
CP029678.1\|AWQ94907.1\|1017385_1018288_+\|fumarylacetoacetate-(FAA)-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.0042e-87
CP029678.1\|AWQ95722.1\|1006578_1007910_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
CP029678.1\|AWQ94435.1\|992849_993278_-\|na(+)/H(+)-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
CP029678.1\|AWQ95250.1\|997262_997640_+\|S1-RNA-binding-domain-protein	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
CP029678.1\|AWQ93550.1\|1013566_1017220_+\|helicase-exonuclease-AddAB,-AddA-subunit	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
CP029678.1\|AWQ95741.1\|1002482_1003412_-\|glycerophosphoryl-diester-phosphodiesterase-family-protein	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	5.11302e-151
CP029678.1\|AWQ93806.1\|1009354_1009930_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	4.05406e-53
CP029678.1\|AWQ93808.1\|991019_992516_-\|na(+)/H(+)-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
CP029678.1\|AWQ94883.1\|1008234_1008810_+\|hypothetical-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.01759e-40
CP029678.1\|AWQ95254.1\|993270_995676_-\|na(+)/H(+)-antiporter-subunit-A1	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
CP029678.1\|AWQ94895.1\|1003653_1005033_-\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
CP029678.1\|AWQ93669.1\|1005022_1006228_-\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
CP029678.1\|AWQ95756.1\|1010089_1013566_+\|helicase-exonuclease-AddAB,-AddB-subunit	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
CP029678.1\|AWQ94484.1\|998001_999129_+\|flavin-oxidoreductase-/-NADH-oxidase-family-protein	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
CP029678.1\|AWQ94372.1\|996253_996847_+\|cyclophilin-type-peptidyl-prolyl-cis-trans-isomerase/CLD-family-protein	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
CP029678.1\|AWQ94415.1\|992508_992763_-\|na(+)/H(+)-antiporter-subunit-C	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	7.96732e-49
CP029678.1\|AWQ93519.1\|999436_1000627_+\|ornithine--oxo-acid-transaminase	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
CP029678.1\|AWQ94973.1\|1008814_1009339_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.63848e-48
CP029678.1\|AWQ94302.1\|1000735_1001980_+\|NAD-specific-glutamate-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0

>CP029678.1|AWQ94302.1|1000735_1001980_+|NAD-specific-glutamate-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVDEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>CP029678.1|AWQ93519.1|999436_1000627_+|ornithine--oxo-acid-transaminase
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>CP029678.1|AWQ94484.1|998001_999129_+|flavin-oxidoreductase-/-NADH-oxidase-family-protein
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSNIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPVAVIEEVLKAKEAYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>CP029678.1|AWQ95250.1|997262_997640_+|S1-RNA-binding-domain-protein
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>CP029678.1|AWQ94372.1|996253_996847_+|cyclophilin-type-peptidyl-prolyl-cis-trans-isomerase/CLD-family-protein
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>CP029678.1|AWQ93428.1|995806_996190_-|kinase-associated-B-family-protein
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHDRKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>CP029678.1|AWQ95254.1|993270_995676_-|na(+)/H(+)-antiporter-subunit-A1
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>CP029678.1|AWQ94435.1|992849_993278_-|na(+)/H(+)-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>CP029678.1|AWQ94415.1|992508_992763_-|na(+)/H(+)-antiporter-subunit-C
MGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>CP029678.1|AWQ93808.1|991019_992516_-|na(+)/H(+)-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVYFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK
>CP029678.1|AWQ95741.1|1002482_1003412_-|glycerophosphoryl-diester-phosphodiesterase-family-protein
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>CP029678.1|AWQ94895.1|1003653_1005033_-|argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPSYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>CP029678.1|AWQ93669.1|1005022_1006228_-|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>CP029678.1|AWQ95722.1|1006578_1007910_+|glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>CP029678.1|AWQ94883.1|1008234_1008810_+|hypothetical-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE
>CP029678.1|AWQ94973.1|1008814_1009339_+|signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDQDNNKHDSRQFGLIDKKDIIGNVSLRYYPFSKWTVQFKS
>CP029678.1|AWQ93806.1|1009354_1009930_+|signal-peptidase-I
MKKEILEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>CP029678.1|AWQ95756.1|1010089_1013566_+|helicase-exonuclease-AddAB,-AddB-subunit
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>CP029678.1|AWQ93550.1|1013566_1017220_+|helicase-exonuclease-AddAB,-AddA-subunit
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPKNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDSVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYRYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>CP029678.1|AWQ94907.1|1017385_1018288_+|fumarylacetoacetate-(FAA)-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK

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Crispr_ID: CP029678_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029678_6

1135803-1135890

Orphan

Consensus_repeat	Method
CCCCTAACAACTAAAAGTTGTAAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029678_6

>merge|CP029678|6|1135803-1135890|CRISPRCasFinder
CCCCTAACAACTAAAAGTTGTAAGGAAGGAGAGGGATACATGCGCCGAGCACATGCATAAAATCCCCTAACAACTAAAAGTTGTAAGG

>CP029678|6|5|1135803-1135890|CRISPRCasFinder
CCCCTAACAACTAAAAGTTGTAAGG	AAGGAGAGGGATACATGCGCCGAGCACATGCATAAAAT
CCCCTAACAACTAAAAGTTGTAAGG

Protein	Signature genes	Signature genes Name	Protein_function
CP029678.1\|AWQ94871.1\|1144992_1145655_+\|trkA-N-domain-protein	unknown	unknown	gnl\|CDD\|223643
CP029678.1\|AWQ93005.1\|1127902_1128931_+\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
CP029678.1\|AWQ94485.1\|1133325_1134726_-\|heme-ABC-exporter,-ATP-binding-protein-CcmA	unknown	unknown	gnl\|CDD\|213192
CP029678.1\|AWQ95572.1\|1137905_1139078_+\|S-adenosylmethionine-dependent-methyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224017
CP029678.1\|AWQ94006.1\|1135899_1136034_-\|hypothetical-protein	unknown	unknown	unknown
CP029678.1\|AWQ93006.1\|1140096_1141815_+\|phosphoenolpyruvate-protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
CP029678.1\|AWQ93015.1\|1131014_1132262_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|237507
CP029678.1\|AWQ93104.1\|1139131_1139674_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368297
CP029678.1\|AWQ95232.1\|1143840_1144860_+\|cytochrome-oxidase-subunit-II-family-protein	unknown	unknown	gnl\|CDD\|224213
CP029678.1\|AWQ94975.1\|1136185_1137481_+\|putative-membrane-protein	unknown	unknown	unknown
CP029678.1\|AWQ93267.1\|1123593_1124265_+\|phosphoribosylformylglycinamidine-synthase-I	unknown	unknown	gnl\|CDD\|235140
CP029678.1\|AWQ93718.1\|1128933_1129500_+\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|223376
CP029678.1\|AWQ93746.1\|1142482_1143844_+\|bacterial-Cytochrome-Ubiquinol-Oxidase-family-protein	unknown	unknown	gnl\|CDD\|376587
CP029678.1\|AWQ93217.1\|1124257_1126447_+\|phosphoribosylformylglycinamidine-synthase-II	unknown	unknown	gnl\|CDD\|234921
CP029678.1\|AWQ93264.1\|1139827_1140094_+\|phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|237503
CP029678.1\|AWQ93401.1\|1134740_1135316_-\|ABC-type-cobalt-transport-system,-permease-component-family-protein	unknown	unknown	gnl\|CDD\|227065
CP029678.1\|AWQ94640.1\|1126425_1127910_+\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
CP029678.1\|AWQ95114.1\|1132526_1133333_-\|cobalt-transport-family-protein	unknown	unknown	gnl\|CDD\|223692
CP029678.1\|AWQ93043.1\|1129514_1130993_+\|phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
CP029678.1\|AWQ95742.1\|1142051_1142285_-\|glutaredoxin-family-protein	unknown	unknown	gnl\|CDD\|239274

Protein	Function_ID	Function_description	E-value
CP029678.1\|AWQ94871.1\|1144992_1145655_+\|trkA-N-domain-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	4.35421e-66
CP029678.1\|AWQ93005.1\|1127902_1128931_+\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
CP029678.1\|AWQ94485.1\|1133325_1134726_-\|heme-ABC-exporter,-ATP-binding-protein-CcmA	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.67975e-64
CP029678.1\|AWQ93006.1\|1140096_1141815_+\|phosphoenolpyruvate-protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
CP029678.1\|AWQ93015.1\|1131014_1132262_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|237507	PRK13790, PRK13790, phosphoribosylamine--glycine ligase; Provisional.	0
CP029678.1\|AWQ93104.1\|1139131_1139674_+\|hypothetical-protein	gnl\|CDD\|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	0.00779365
CP029678.1\|AWQ95232.1\|1143840_1144860_+\|cytochrome-oxidase-subunit-II-family-protein	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	6.42118e-76
CP029678.1\|AWQ95572.1\|1137905_1139078_+\|S-adenosylmethionine-dependent-methyltransferase-family-protein	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	5.6543e-145
CP029678.1\|AWQ93267.1\|1123593_1124265_+\|phosphoribosylformylglycinamidine-synthase-I	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	1.77638e-140
CP029678.1\|AWQ93718.1\|1128933_1129500_+\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|223376	COG0299, PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism].	7.23817e-92
CP029678.1\|AWQ93746.1\|1142482_1143844_+\|bacterial-Cytochrome-Ubiquinol-Oxidase-family-protein	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	1.72131e-164
CP029678.1\|AWQ93217.1\|1124257_1126447_+\|phosphoribosylformylglycinamidine-synthase-II	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
CP029678.1\|AWQ93264.1\|1139827_1140094_+\|phosphocarrier-protein-HPr	gnl\|CDD\|237503	PRK13780, PRK13780, phosphocarrier protein HPr; Provisional.	2.44795e-51
CP029678.1\|AWQ93401.1\|1134740_1135316_-\|ABC-type-cobalt-transport-system,-permease-component-family-protein	gnl\|CDD\|227065	COG4721, COG4721, ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism].	4.34592e-70
CP029678.1\|AWQ94640.1\|1126425_1127910_+\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
CP029678.1\|AWQ95114.1\|1132526_1133333_-\|cobalt-transport-family-protein	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	7.39205e-29
CP029678.1\|AWQ93043.1\|1129514_1130993_+\|phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
CP029678.1\|AWQ95742.1\|1142051_1142285_-\|glutaredoxin-family-protein	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	5.00495e-16

>CP029678.1|AWQ93401.1|1134740_1135316_-|ABC-type-cobalt-transport-system,-permease-component-family-protein
MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQLTNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELVFAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVAGVLSYLLVKALDKTGVTKLFRPAAKEDYDNL
>CP029678.1|AWQ94485.1|1133325_1134726_-|heme-ABC-exporter,-ATP-binding-protein-CcmA
MLKVSDLRLKYPSGQRKIFDHLNITIQDKEKVLLLGPSGCGKSTLLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQLPREDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAMLDVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQKYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGLGEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQFITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLQNVKDQHPYELSIGQKRRLSVATALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRLKISDGALLDCDGDTNV
>CP029678.1|AWQ95114.1|1132526_1133333_-|cobalt-transport-family-protein
MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYITILMLVFLLMFNGTQFKITAIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTESLVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLMISSLIQLRRSLKMRYQMIDAANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRDGPRTYYYNVPFSYKDIIFIIVLIAIITMAYYCSITLPITGIDDVRLGRVG
>CP029678.1|AWQ93015.1|1131014_1132262_+|phosphoribosylamine--glycine-ligase
MNVLVIGAGGREHALAYKLNQSNLVKQVFVIPGNEAMTPIAEVHTEISESDHQAILDFAKRQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMEKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKDGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVQDAQRDAYKKVSQIQSDHLFYRHDIANKALQLK
>CP029678.1|AWQ93043.1|1129514_1130993_+|phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPATVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPSGSIKDQDSIDMANKHGIAMVVTGTRHFKH
>CP029678.1|AWQ93718.1|1128933_1129500_+|phosphoribosylglycinamide-formyltransferase
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRKCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
>CP029678.1|AWQ93005.1|1127902_1128931_+|phosphoribosylformylglycinamidine-cyclo-ligase
MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDGSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDTNEMYNIFNMGIGYTVIVDEKDVSRALKILAEQNVEAYQIGHIVKNESTAIELLGV
>CP029678.1|AWQ94640.1|1126425_1127910_+|amidophosphoribosyltransferase
MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
>CP029678.1|AWQ93217.1|1124257_1126447_+|phosphoribosylformylglycinamidine-synthase-II
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGDHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
>CP029678.1|AWQ93267.1|1123593_1124265_+|phosphoribosylformylglycinamidine-synthase-I
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGAMASVAPIISEVKRLAAEGKPVLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANNQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV
>CP029678.1|AWQ94006.1|1135899_1136034_-|hypothetical-protein
MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
>CP029678.1|AWQ94975.1|1136185_1137481_+|putative-membrane-protein
MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVDTHVHNVWEFLNAFFSEIIKVMSRFIGDFPIVSAIVIIIFGILVMLIGHTLLRTIKYDYDISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHFMWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRRALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAKRDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFVSGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLTEFINIMIHGLLLSVFITPTLLLMLLAIIISYSLQLRERP
>CP029678.1|AWQ95572.1|1137905_1139078_+|S-adenosylmethionine-dependent-methyltransferase-family-protein
MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDKSQYVATAYVGRQHKGLGWVLTYDKAQQINTAFFVKLFNTALAERDYYFNIDGTNAFRLFNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDSEYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRDQYAKERHVLNLFSYTGAFSAIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDFYKYAARHGHSYDTIVIDPPSFARNKKRTFSVQKDYDKLINGALNILSSEGTLLLCTNASVYPLKQFKNTIKKTLEESGVDYELTEVMGLPKDFKTHPHYKPSKYLKAVFVNIRH
>CP029678.1|AWQ93104.1|1139131_1139674_+|hypothetical-protein
MGFKNNLTSNLTNKIGNSVFKIENVDGKGAMPTTIQELRERRQRAEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVKERIMSAAAIQGSQFIGKRISNAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYFMNKIGKDHIQKCENVIKNVM
>CP029678.1|AWQ93264.1|1139827_1140094_+|phosphocarrier-protein-HPr
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
>CP029678.1|AWQ93006.1|1140096_1141815_+|phosphoenolpyruvate-protein-phosphotransferase
MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANAATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMGGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK
>CP029678.1|AWQ95742.1|1142051_1142285_-|glutaredoxin-family-protein
MSEIIVYTQNDCPPCTFVKNYLNEHHIDFEERNINNQQYRNEMIDFDAFSTPFILLNGNPMYHVDLDEINKVLNIQD
>CP029678.1|AWQ93746.1|1142482_1143844_+|bacterial-Cytochrome-Ubiquinol-Oxidase-family-protein
MDTVEIGRFLTAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKNDLQYIAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAFFFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKNGKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKKALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDEKTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCFVISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGYMRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAHEDVNRLAKKQGGEIEK
>CP029678.1|AWQ95232.1|1143840_1144860_+|cytochrome-oxidase-subunit-II-family-protein
MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKINHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSFYAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLSPFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFLSLRIQNSEHFYSAVFDYWWMFGISFLFFALASLLTFFKKKHGLAFVFVILQMMFAFFGYGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYVEGKKS
>CP029678.1|AWQ94871.1|1144992_1145655_+|trkA-N-domain-protein
MGKEYVVIGLGRFGGSIVRELNALDMDVMAIDHDENRVNEYSDIATHAVVADTTDEAVMKSLGIRNFDHVIVAIGENIQSSTLTTLILKELGVKKVTAKAQNDYHAKILNKIGADTVVHPERDMGRRIAHNVASASVLDYLELADEHSIVELKATEKMAGQSIIDLDIRAQYGINIIAIKRGKEFIISPNPNINLEIGDILIMIGHDNDLNRFEKNIATR

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Crispr_ID: CP029678_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029678_7

2077819-2077897

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACCTGCA	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of CP029678_7

>merge|CP029678|7|2077819-2077897|CRISPRCasFinder
TGTTGGGGCCCCGCCAACCTGCACATTATCGTAAGCTGACTTTTCGTCAGCTTCTGTGTTGGGGCCCCGCCAACCTGCA

>CP029678|7|6|2077819-2077897|CRISPRCasFinder
TGTTGGGGCCCCGCCAACCTGCA	CATTATCGTAAGCTGACTTTTCGTCAGCTTCTG
TGTTGGGGCCCCGCCAACCTGCA

Protein	Signature genes	Signature genes Name	Protein_function
CP029678.1\|AWQ94754.1\|2071195_2071396_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227177
CP029678.1\|AWQ93404.1\|2078163_2079150_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226614
CP029678.1\|AWQ94555.1\|2085443_2085974_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378690
CP029678.1\|AWQ93299.1\|2080277_2081009_-\|cobB/CobQ-like-glutamine-amidotransferase-domain-protein	unknown	unknown	gnl\|CDD\|225974
CP029678.1\|AWQ94813.1\|2069936_2071184_-\|thermophilic-metalloprotease-family-protein	unknown	unknown	gnl\|CDD\|376723
CP029678.1\|AWQ94529.1\|2079639_2080092_-\|hypothetical-protein	unknown	unknown	unknown
CP029678.1\|AWQ94577.1\|2086143_2087505_-\|23S-rRNA-(uracil-5-)-methyltransferase-RumA	unknown	unknown	gnl\|CDD\|225174
CP029678.1\|AWQ95123.1\|2072013_2072289_+\|hypothetical-protein	unknown	unknown	unknown
CP029678.1\|AWQ95638.1\|2071542_2072007_+\|low-molecular-weight-protein-tyrosine-phosphatase-PtpA	unknown	unknown	gnl\|CDD\|319971
CP029678.1\|AWQ93637.1\|2083504_2084059_+\|exonuclease-family-protein	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
CP029678.1\|AWQ95753.1\|2076274_2076661_-\|hypothetical-protein	unknown	unknown	unknown
CP029678.1\|AWQ93157.1\|2087585_2088533_-\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|183982
CP029678.1\|AWQ95582.1\|2082615_2083116_+\|ferritin	unknown	unknown	gnl\|CDD\|224445
CP029678.1\|AWQ95346.1\|2084126_2085197_-\|impB/mucB/samB-family-protein	unknown	unknown	gnl\|CDD\|235035
CP029678.1\|AWQ94164.1\|2074518_2075562_-\|sensor-protein-VraS	unknown	unknown	gnl\|CDD\|226951
CP029678.1\|AWQ94879.1\|2072566_2073784_+\|yihY-family-inner-membrane-domain-protein	unknown	unknown	gnl\|CDD\|224214
CP029678.1\|AWQ94804.1\|2073899_2074529_-\|response-regulator	unknown	unknown	gnl\|CDD\|225107
CP029678.1\|AWQ95012.1\|2081010_2082324_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223840
CP029678.1\|AWQ93433.1\|2075558_2076260_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227100
CP029678.1\|AWQ93502.1\|2076877_2077636_-\|methionine-aminopeptidase,-type-I	unknown	unknown	gnl\|CDD\|235576

Protein	Function_ID	Function_description	E-value
CP029678.1\|AWQ94754.1\|2071195_2071396_-\|hypothetical-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	2.44511e-24
CP029678.1\|AWQ93404.1\|2078163_2079150_+\|hypothetical-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.20478e-76
CP029678.1\|AWQ94555.1\|2085443_2085974_-\|hypothetical-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.4991e-11
CP029678.1\|AWQ93299.1\|2080277_2081009_-\|cobB/CobQ-like-glutamine-amidotransferase-domain-protein	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	3.33663e-121
CP029678.1\|AWQ94813.1\|2069936_2071184_-\|thermophilic-metalloprotease-family-protein	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
CP029678.1\|AWQ94577.1\|2086143_2087505_-\|23S-rRNA-(uracil-5-)-methyltransferase-RumA	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	0
CP029678.1\|AWQ95638.1\|2071542_2072007_+\|low-molecular-weight-protein-tyrosine-phosphatase-PtpA	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
CP029678.1\|AWQ93637.1\|2083504_2084059_+\|exonuclease-family-protein	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	1.92778e-75
CP029678.1\|AWQ93157.1\|2087585_2088533_-\|diacylglycerol-kinase	gnl\|CDD\|183982	PRK13337, PRK13337, putative lipid kinase; Reviewed.	0
CP029678.1\|AWQ95582.1\|2082615_2083116_+\|ferritin	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
CP029678.1\|AWQ95346.1\|2084126_2085197_-\|impB/mucB/samB-family-protein	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
CP029678.1\|AWQ94164.1\|2074518_2075562_-\|sensor-protein-VraS	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
CP029678.1\|AWQ94879.1\|2072566_2073784_+\|yihY-family-inner-membrane-domain-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	4.24482e-85
CP029678.1\|AWQ94804.1\|2073899_2074529_-\|response-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.91794e-79
CP029678.1\|AWQ95012.1\|2081010_2082324_-\|hypothetical-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	7.18737e-99
CP029678.1\|AWQ93433.1\|2075558_2076260_-\|hypothetical-protein	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
CP029678.1\|AWQ93502.1\|2076877_2077636_-\|methionine-aminopeptidase,-type-I	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126

>CP029678.1|AWQ93502.1|2076877_2077636_-|methionine-aminopeptidase,-type-I
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>CP029678.1|AWQ95753.1|2076274_2076661_-|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>CP029678.1|AWQ93433.1|2075558_2076260_-|hypothetical-protein
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>CP029678.1|AWQ94164.1|2074518_2075562_-|sensor-protein-VraS
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>CP029678.1|AWQ94804.1|2073899_2074529_-|response-regulator
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>CP029678.1|AWQ94879.1|2072566_2073784_+|yihY-family-inner-membrane-domain-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIIFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>CP029678.1|AWQ95123.1|2072013_2072289_+|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>CP029678.1|AWQ95638.1|2071542_2072007_+|low-molecular-weight-protein-tyrosine-phosphatase-PtpA
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>CP029678.1|AWQ94754.1|2071195_2071396_-|hypothetical-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHE
>CP029678.1|AWQ94813.1|2069936_2071184_-|thermophilic-metalloprotease-family-protein
MTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHEIKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAGKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF
>CP029678.1|AWQ93404.1|2078163_2079150_+|hypothetical-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>CP029678.1|AWQ94529.1|2079639_2080092_-|hypothetical-protein
MQHEKMNDERNLTMKPTKVILKDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEVKFEFALFDSDMDNLKHMDCDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVAKSDFTKFINELASLH
>CP029678.1|AWQ93299.1|2080277_2081009_-|cobB/CobQ-like-glutamine-amidotransferase-domain-protein
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
>CP029678.1|AWQ95012.1|2081010_2082324_-|hypothetical-protein
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLYLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>CP029678.1|AWQ95582.1|2082615_2083116_+|ferritin
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>CP029678.1|AWQ93637.1|2083504_2084059_+|exonuclease-family-protein
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKIHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>CP029678.1|AWQ95346.1|2084126_2085197_-|impB/mucB/samB-family-protein
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>CP029678.1|AWQ94555.1|2085443_2085974_-|hypothetical-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ
>CP029678.1|AWQ94577.1|2086143_2087505_-|23S-rRNA-(uracil-5-)-methyltransferase-RumA
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVTSIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGTIGLYMAPLAKHVYGVEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
>CP029678.1|AWQ93157.1|2087585_2088533_-|diacylglycerol-kinase
MRKRARIIYNPTSGKELFKRELPDALIKLEKAGYETSAYATEKIGDATLEAERAMHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPFAYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGYFTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGGKLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE

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Crispr_ID: CP029678_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029678_8

2312770-2312920

Orphan

Consensus_repeat	Method
AACTTTAGTTGTTAGGGGCTCTTATGCA	CRISPRCasFinder

2 spacers

csa3

The CRISPR arrays of CP029678_8

>merge|CP029678|8|2312770-2312920|CRISPRCasFinder
AACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTAAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTCAACTTTAGTTGTTAGGGGCTTCTTTCTA

>CP029678|8|7|2312770-2312920|CRISPRCasFinder
AACTTTAGTTGTTAGGGGCTCTTATGCA	TGCGCTTAGCGCAGGCGCTCCTACTTTTA
AACTTTAGTTGTTAGGGGCTCTTATGCA	GTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTC
AACTTTAGTTGTTAGGGGCTTCTTTCTA

Protein	Signature genes	Signature genes Name	Protein_function
CP029678.1\|AWQ93915.1\|2311660_2312752_+\|putative-membrane-protein	unknown	unknown	unknown
CP029678.1\|AWQ94718.1\|2310092_2310413_+\|HTH-type-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
CP029678.1\|AWQ95655.1\|2318203_2320009_-\|glutamine-fructose-6-phosphate-transaminase	unknown	unknown	gnl\|CDD\|234729
CP029678.1\|AWQ94269.1\|2316264_2317122_-\|HAD-hydrolase,-IIB-family-protein	unknown	unknown	gnl\|CDD\|223635
CP029678.1\|AWQ93651.1\|2305596_2306970_-\|EVE-domain-protein	unknown	unknown	gnl\|CDD\|376640
CP029678.1\|AWQ93207.1\|2303251_2303962_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
CP029678.1\|AWQ95485.1\|2310414_2311395_+\|cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter	unknown	unknown	gnl\|CDD\|224151
CP029678.1\|AWQ93577.1\|2304082_2304526_-\|DNA-protection-during-starvation-protein-1	unknown	unknown	gnl\|CDD\|223854
CP029678.1\|AWQ94746.1\|2324840_2325947_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
CP029678.1\|AWQ93438.1\|2320689_2322228_+\|PTS-system-mannitol-specific-EIICB-component	unknown	unknown	gnl\|CDD\|225123
CP029678.1\|AWQ94605.1\|2322262_2324395_+\|PRD-domain-protein	unknown	unknown	gnl\|CDD\|226234
CP029678.1\|AWQ95434.1\|2307641_2307872_-\|putative-membrane-protein	unknown	unknown	unknown
CP029678.1\|AWQ93456.1\|2314042_2315179_-\|SAP-domain-protein	unknown	unknown	gnl\|CDD\|366887
CP029678.1\|AWQ94654.1\|2309275_2309941_-\|NADH(P)-binding-family-protein	unknown	unknown	gnl\|CDD\|187554
CP029678.1\|AWQ95261.1\|2304725_2305139_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225556
CP029678.1\|AWQ93834.1\|2317189_2317972_-\|ABC-transporter-family-protein	unknown	unknown	gnl\|CDD\|224044
CP029678.1\|AWQ94648.1\|2307902_2308841_-\|mannose-6-phosphate-isomerase,-class-I	unknown	unknown	gnl\|CDD\|224399
CP029678.1\|AWQ93996.1\|2326265_2328266_-\|LPXTG-cell-wall-anchor-domain-protein	unknown	unknown	gnl\|CDD\|336743
CP029678.1\|AWQ94857.1\|2313780_2313984_-\|resolvase,-N-terminal-domain-protein	unknown	unknown	gnl\|CDD\|239737
CP029678.1\|AWQ95023.1\|2324406_2324841_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014

Protein	Function_ID	Function_description	E-value
CP029678.1\|AWQ94857.1\|2313780_2313984_-\|resolvase,-N-terminal-domain-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	1.78732e-14
CP029678.1\|AWQ94718.1\|2310092_2310413_+\|HTH-type-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
CP029678.1\|AWQ95655.1\|2318203_2320009_-\|glutamine-fructose-6-phosphate-transaminase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP029678.1\|AWQ95261.1\|2304725_2305139_-\|hypothetical-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
CP029678.1\|AWQ93651.1\|2305596_2306970_-\|EVE-domain-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.73013e-06
CP029678.1\|AWQ93207.1\|2303251_2303962_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
CP029678.1\|AWQ95485.1\|2310414_2311395_+\|cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.049e-108
CP029678.1\|AWQ93577.1\|2304082_2304526_-\|DNA-protection-during-starvation-protein-1	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
CP029678.1\|AWQ94746.1\|2324840_2325947_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
CP029678.1\|AWQ93438.1\|2320689_2322228_+\|PTS-system-mannitol-specific-EIICB-component	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
CP029678.1\|AWQ94605.1\|2322262_2324395_+\|PRD-domain-protein	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	9.74009e-67
CP029678.1\|AWQ94654.1\|2309275_2309941_-\|NADH(P)-binding-family-protein	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.03984e-46
CP029678.1\|AWQ94269.1\|2316264_2317122_-\|HAD-hydrolase,-IIB-family-protein	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	5.39747e-59
CP029678.1\|AWQ93834.1\|2317189_2317972_-\|ABC-transporter-family-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	4.88024e-103
CP029678.1\|AWQ94648.1\|2307902_2308841_-\|mannose-6-phosphate-isomerase,-class-I	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
CP029678.1\|AWQ93996.1\|2326265_2328266_-\|LPXTG-cell-wall-anchor-domain-protein	gnl\|CDD\|336743	pfam07564, DUF1542, Domain of Unknown Function (DUF1542). This domain is found in several cell surface proteins. Some are involved in antibiotic resistance and/or cellular adhesion.	3.35569e-07
CP029678.1\|AWQ93456.1\|2314042_2315179_-\|SAP-domain-protein	gnl\|CDD\|366887	pfam02037, SAP, SAP domain. The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.	3.91533e-06
CP029678.1\|AWQ95023.1\|2324406_2324841_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62

>CP029678.1|AWQ93915.1|2311660_2312752_+|putative-membrane-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>CP029678.1|AWQ95485.1|2310414_2311395_+|cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>CP029678.1|AWQ94718.1|2310092_2310413_+|HTH-type-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>CP029678.1|AWQ94654.1|2309275_2309941_-|NADH(P)-binding-family-protein
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDAATVLKEIVTSNHFNHQEFQIISGDQDIKDALTQFENETD
>CP029678.1|AWQ94648.1|2307902_2308841_-|mannose-6-phosphate-isomerase,-class-I
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>CP029678.1|AWQ95434.1|2307641_2307872_-|putative-membrane-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>CP029678.1|AWQ93651.1|2305596_2306970_-|EVE-domain-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRISNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHG
>CP029678.1|AWQ95261.1|2304725_2305139_-|hypothetical-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>CP029678.1|AWQ93577.1|2304082_2304526_-|DNA-protection-during-starvation-protein-1
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>CP029678.1|AWQ93207.1|2303251_2303962_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>CP029678.1|AWQ94857.1|2313780_2313984_-|resolvase,-N-terminal-domain-protein
MIVYQRKINIDTLKEFGCGCVYSERISGVKRTELVKCLDYLRESDTLVVYQLDRLGRTTKLLIELSQ
>CP029678.1|AWQ93456.1|2314042_2315179_-|SAP-domain-protein
MSVNARDLLVLHTNVNRLVGEEIFANKCLANNDVQIMNSIKKLIEAELLTTTNDFEVSIYKKTRPELQSILKSFGIKTTGNKPDLIKRIDDNFHIINNLDLPYVYIPTKKGEEILKKTEYLTSFIQSYGEISLERAYYLVENYIDENCDDKVAEIYKFEFQRKYDNGEFDFNHGYNFELNMLIDHYKRDVKDYDNARKYSNIYLYFGLRDFLKKLMSNYSYYDSKGNIDLNEIQNDLNRFINSSASGMYERLIYNENLSNNIMFELFKKDTQDYSDLEEQLIEKFINYVVSNVKKESRSNTLIELSKILENGYTIDKEEFKKEDDYLSKYIFTDIDYLKKLESKINVAIDIRSGEIHLVLDDDSLDILIQNQKYGNEF
>CP029678.1|AWQ94269.1|2316264_2317122_-|HAD-hydrolase,-IIB-family-protein
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAEHFLAE
>CP029678.1|AWQ93834.1|2317189_2317972_-|ABC-transporter-family-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEIRNEAHQLLKLVGMFAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITANFSKILLLKDGQSIQQGAVEDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>CP029678.1|AWQ95655.1|2318203_2320009_-|glutamine-fructose-6-phosphate-transaminase
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>CP029678.1|AWQ93438.1|2320689_2322228_+|PTS-system-mannitol-specific-EIICB-component
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>CP029678.1|AWQ94605.1|2322262_2324395_+|PRD-domain-protein
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLDQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFISDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>CP029678.1|AWQ95023.1|2324406_2324841_+|mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>CP029678.1|AWQ94746.1|2324840_2325947_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVLAETSQYITNEFDFTEAEQAAYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>CP029678.1|AWQ93996.1|2326265_2328266_-|LPXTG-cell-wall-anchor-domain-protein
MDNGDVDDALTQGKAAIDAIQVDATVKPKANQAIEVKAEDTKESIDQSDQLTAEEKTEALAMIKQITDQAKQGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVNADATTEEKEAFTNALEDILSKATEDISDQTTNAEIATVKNSALEQLKAQRINPEVKKNALEAIREVVNKQIEIIKNADADASAKEIARTDLGRYFDRFADKLDKTQTNAEVAELQNVTIPAIEAIVPQNDPDANDTNNGIDNNDATANSNANATPENTGQPNVSETTANGKADASPTTPNNSDAATGETTATSATDDANDKPQANNNSSVDASTNSPTMDNDVTSKPEVESTNNGTTDKPVTETDNATPAESTTNNNSTTTATNENAPTGSTATAPTTASTEAASSADSKDNASVNDSKQNAEVNNSAESQSTNDKVAQPKSENKAKAEKDGSDSTNQSMVESTTETLPSADITEPNVPSNTSKDKEESTTNQTDAGQLKSETNVASNEADKSPSKADTEVSNKPSTSASSEAKEKMTSTNVSQKDDTATADTNDTQKSVGSAANNKATQNDGANASPATVSNGSNSANQDMLNVTNTDDHQAKTKSAQQGKVNKAKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKDQQTEE

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Crispr_ID: CP029678_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029678_9

2436688-2436881

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACTTGCA	CRT

3 spacers

The CRISPR arrays of CP029678_9

>merge|CP029678|9|2436688-2436881|CRT
TGTTGGGGCCCCGCCAACTTGCACATTATTGTATGCTGACTTTTCGTCACCTTCTGTGTTGGGGCCCCGTTCCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTCTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTGTA

>CP029678|9|2|2436688-2436881|CRT
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTATGCTGACTTTTCGTCACCTTCTG
TGTTGGGGCCCCGTTCCCCAACT	TGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTA
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTAAGCTGACTTTCTGTCAGCTTCTG
TGTTGGGGCCCCGCCAACTTGTA

Protein	Signature genes	Signature genes Name	Protein_function
CP029678.1\|AWQ93038.1\|2434668_2435880_+\|sugar-(and-other)-transporter-family-protein	unknown	unknown	gnl\|CDD\|341042
CP029678.1\|AWQ93868.1\|2435981_2436332_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
CP029678.1\|AWQ93987.1\|2439851_2441111_-\|molybdopterin-molybdenumtransferase	unknown	unknown	gnl\|CDD\|238452
CP029678.1\|AWQ94361.1\|2426174_2427083_-\|membrane-transport-family-protein	unknown	unknown	gnl\|CDD\|223751
CP029678.1\|AWQ95706.1\|2442206_2443211_-\|thiF-family-protein	unknown	unknown	gnl\|CDD\|181084
CP029678.1\|AWQ94637.1\|2431412_2432678_-\|glycine-glycyltransferase	unknown	unknown	gnl\|CDD\|225224
CP029678.1\|AWQ95425.1\|2427215_2427380_+\|hypothetical-protein	unknown	unknown	unknown
CP029678.1\|AWQ95736.1\|2438064_2438664_-\|putative-molybdenum-cofactor-guanylyltransferase	unknown	unknown	gnl\|CDD\|234725
CP029678.1\|AWQ93586.1\|2438670_2438904_-\|molybdopterin-converting-factor,-subunit-1	unknown	unknown	gnl\|CDD\|340452
CP029678.1\|AWQ93041.1\|2427624_2427942_+\|putative-membrane-protein	unknown	unknown	unknown
CP029678.1\|AWQ93512.1\|2433309_2434074_-\|glyoxalase-like-domain-protein	unknown	unknown	gnl\|CDD\|379203
CP029678.1\|AWQ94859.1\|2441669_2442176_-\|molybdenum-cofactor-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|223595
CP029678.1\|AWQ94799.1\|2425872_2426004_-\|hypothetical-protein	unknown	unknown	unknown
CP029678.1\|AWQ93897.1\|2434235_2434676_+\|winged-helix-DNA-binding-domain-protein	unknown	unknown	gnl\|CDD\|197670
CP029678.1\|AWQ95247.1\|2441173_2441668_+\|molybdenum-cofactor-biosynthesis-protein-C	unknown	unknown	gnl\|CDD\|236483
CP029678.1\|AWQ95109.1\|2438909_2439356_-\|molybdopterin-synthase-catalytic-subunit	unknown	unknown	gnl\|CDD\|223391
CP029678.1\|AWQ94801.1\|2428128_2431296_-\|swarming-motility-protein-SwrC	unknown	unknown	gnl\|CDD\|223911
CP029678.1\|AWQ94774.1\|2437022_2438045_-\|molybdenum-cofactor-biosynthesis-protein-A	unknown	unknown	gnl\|CDD\|274250
CP029678.1\|AWQ93642.1\|2439369_2439855_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
CP029678.1\|AWQ93941.1\|2443380_2443986_-\|ABC-transporter-family-protein	unknown	unknown	gnl\|CDD\|226628

Protein	Function_ID	Function_description	E-value
CP029678.1\|AWQ93038.1\|2434668_2435880_+\|sugar-(and-other)-transporter-family-protein	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.27961e-72
CP029678.1\|AWQ93868.1\|2435981_2436332_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
CP029678.1\|AWQ93987.1\|2439851_2441111_-\|molybdopterin-molybdenumtransferase	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.49423e-160
CP029678.1\|AWQ94361.1\|2426174_2427083_-\|membrane-transport-family-protein	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	1.24911e-42
CP029678.1\|AWQ95706.1\|2442206_2443211_-\|thiF-family-protein	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	3.67241e-132
CP029678.1\|AWQ95736.1\|2438064_2438664_-\|putative-molybdenum-cofactor-guanylyltransferase	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
CP029678.1\|AWQ93586.1\|2438670_2438904_-\|molybdopterin-converting-factor,-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
CP029678.1\|AWQ93512.1\|2433309_2434074_-\|glyoxalase-like-domain-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
CP029678.1\|AWQ94859.1\|2441669_2442176_-\|molybdenum-cofactor-biosynthesis-protein-B	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	1.02752e-64
CP029678.1\|AWQ94637.1\|2431412_2432678_-\|glycine-glycyltransferase	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	4.8324e-143
CP029678.1\|AWQ93897.1\|2434235_2434676_+\|winged-helix-DNA-binding-domain-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.873e-15
CP029678.1\|AWQ95247.1\|2441173_2441668_+\|molybdenum-cofactor-biosynthesis-protein-C	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	3.63862e-98
CP029678.1\|AWQ95109.1\|2438909_2439356_-\|molybdopterin-synthase-catalytic-subunit	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
CP029678.1\|AWQ94801.1\|2428128_2431296_-\|swarming-motility-protein-SwrC	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
CP029678.1\|AWQ94774.1\|2437022_2438045_-\|molybdenum-cofactor-biosynthesis-protein-A	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
CP029678.1\|AWQ93642.1\|2439369_2439855_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50
CP029678.1\|AWQ93941.1\|2443380_2443986_-\|ABC-transporter-family-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.32197e-115

>CP029678.1|AWQ93868.1|2435981_2436332_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>CP029678.1|AWQ93038.1|2434668_2435880_+|sugar-(and-other)-transporter-family-protein
MTNQGSLNKSPIFTKSFTINFLVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>CP029678.1|AWQ93897.1|2434235_2434676_+|winged-helix-DNA-binding-domain-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLREAHND
>CP029678.1|AWQ93512.1|2433309_2434074_-|glyoxalase-like-domain-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>CP029678.1|AWQ94637.1|2431412_2432678_-|glycine-glycyltransferase
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>CP029678.1|AWQ94801.1|2428128_2431296_-|swarming-motility-protein-SwrC
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>CP029678.1|AWQ93041.1|2427624_2427942_+|putative-membrane-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>CP029678.1|AWQ95425.1|2427215_2427380_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDIEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>CP029678.1|AWQ94361.1|2426174_2427083_-|membrane-transport-family-protein
MTEQFTMIILLIALGYFLKRINFIKATDSQVIATLVLNVTLPSLVIVNLNSAELKLSFSILPILMIIYGIVAKMIAVWFFRKYDNHMRGSVGMMTGAMNIGLFAYPLIEVIWPKTGLIYFVMADIGGAFVMFGITYFVGSYFSEGSDQFDFKYLGKKLLQSVPLVTYIVMFILNISHIHLPHVAIDFFSILSHANMPLSMILLGVMLNFTLERKYIPATIKYLCLHYGLALVAGLLVYVLLPVSDDMIKTTLLVTWMFPVGVAIISYGIQFKYRTLTFIGMTTNLTIIISIIILYVYQAVFV
>CP029678.1|AWQ94799.1|2425872_2426004_-|hypothetical-protein
MYGAYLIYEYHQDFKSIANFKVLKRMINVMMCYCVLFLEPRIS
>CP029678.1|AWQ94774.1|2437022_2438045_-|molybdenum-cofactor-biosynthesis-protein-A
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>CP029678.1|AWQ95736.1|2438064_2438664_-|putative-molybdenum-cofactor-guanylyltransferase
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>CP029678.1|AWQ93586.1|2438670_2438904_-|molybdopterin-converting-factor,-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>CP029678.1|AWQ95109.1|2438909_2439356_-|molybdopterin-synthase-catalytic-subunit
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>CP029678.1|AWQ93642.1|2439369_2439855_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>CP029678.1|AWQ93987.1|2439851_2441111_-|molybdopterin-molybdenumtransferase
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>CP029678.1|AWQ95247.1|2441173_2441668_+|molybdenum-cofactor-biosynthesis-protein-C
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTLIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
>CP029678.1|AWQ94859.1|2441669_2442176_-|molybdenum-cofactor-biosynthesis-protein-B
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIDGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>CP029678.1|AWQ95706.1|2442206_2443211_-|thiF-family-protein
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>CP029678.1|AWQ93941.1|2443380_2443986_-|ABC-transporter-family-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP029678_4	4.1\|895586\|34\|CP029678\|CRISPRCasFinder	895586-895619	34	CP029678.1	1428310-1428343	0	1.0
CP029678_4	4.1\|895586\|34\|CP029678\|CRISPRCasFinder	895586-895619	34	CP029678.1	1517501-1517534	0	1.0
CP029678_9	9.2\|2436767\|36\|CP029678\|CRT	2436767-2436802	36	CP029678.1	1220078-1220113	0	1.0
CP029678_3	3.1\|852263\|26\|CP029678\|CRISPRCasFinder	852263-852288	26	CP029678.1	815200-815225	1	0.962
CP029678_3	3.1\|852263\|26\|CP029678\|CRISPRCasFinder	852263-852288	26	CP029678.1	2877996-2878021	1	0.962
CP029678_3	3.1\|852263\|26\|CP029678\|CRISPRCasFinder	852263-852288	26	CP029678.1	2878052-2878077	1	0.962
CP029678_5	5.1\|1002161\|26\|CP029678\|CRT	1002161-1002186	26	CP029678.1	1002105-1002130	1	0.962
CP029678_5	5.3\|1002275\|26\|CP029678\|CRT	1002275-1002300	26	CP029678.1	852319-852344	1	0.962
CP029678_7	7.1\|2077842\|33\|CP029678\|CRISPRCasFinder	2077842-2077874	33	CP029678.1	852299-852331	1	0.97
CP029678_7	7.1\|2077842\|33\|CP029678\|CRISPRCasFinder	2077842-2077874	33	CP029678.1	1220134-1220166	1	0.97
CP029678_7	7.1\|2077842\|33\|CP029678\|CRISPRCasFinder	2077842-2077874	33	CP029678.1	1428265-1428297	1	0.97
CP029678_7	7.1\|2077842\|33\|CP029678\|CRISPRCasFinder	2077842-2077874	33	CP029678.1	1742773-1742805	1	0.97
CP029678_7	7.1\|2077842\|33\|CP029678\|CRISPRCasFinder	2077842-2077874	33	CP029678.1	2712646-2712678	1	0.97
CP029678_9	9.2\|2436767\|36\|CP029678\|CRT	2436767-2436802	36	CP029678.1	1921220-1921255	1	0.972
CP029678_3	3.1\|852263\|26\|CP029678\|CRISPRCasFinder	852263-852288	26	CP029678.1	815256-815281	2	0.923
CP029678_3	3.1\|852263\|26\|CP029678\|CRISPRCasFinder	852263-852288	26	CP029678.1	1002105-1002130	2	0.923
CP029678_5	5.1\|1002161\|26\|CP029678\|CRT	1002161-1002186	26	CP029678.1	815200-815225	2	0.923
CP029678_5	5.1\|1002161\|26\|CP029678\|CRT	1002161-1002186	26	CP029678.1	2877996-2878021	2	0.923
CP029678_5	5.1\|1002161\|26\|CP029678\|CRT	1002161-1002186	26	CP029678.1	2878052-2878077	2	0.923
CP029678_5	5.3\|1002275\|26\|CP029678\|CRT	1002275-1002300	26	CP029678.1	393419-393444	2	0.923
CP029678_7	7.1\|2077842\|33\|CP029678\|CRISPRCasFinder	2077842-2077874	33	CP029678.1	1517547-1517579	2	0.939
CP029678_9	9.1\|2436711\|33\|CP029678\|CRT	2436711-2436743	33	CP029678.1	852299-852331	2	0.939
CP029678_9	9.1\|2436711\|33\|CP029678\|CRT	2436711-2436743	33	CP029678.1	1220134-1220166	2	0.939
CP029678_9	9.1\|2436711\|33\|CP029678\|CRT	2436711-2436743	33	CP029678.1	1428265-1428297	2	0.939
CP029678_9	9.1\|2436711\|33\|CP029678\|CRT	2436711-2436743	33	CP029678.1	1517547-1517579	2	0.939
CP029678_9	9.1\|2436711\|33\|CP029678\|CRT	2436711-2436743	33	CP029678.1	2712646-2712678	2	0.939
CP029678_9	9.2\|2436767\|36\|CP029678\|CRT	2436767-2436802	36	CP029678.1	1742712-1742747	2	0.944
CP029678_9	9.2\|2436767\|36\|CP029678\|CRT	2436767-2436802	36	CP029678.1	2088645-2088680	2	0.944
CP029678_9	9.3\|2436826\|33\|CP029678\|CRT	2436826-2436858	33	CP029678.1	852299-852331	2	0.939
CP029678_9	9.3\|2436826\|33\|CP029678\|CRT	2436826-2436858	33	CP029678.1	1220134-1220166	2	0.939
CP029678_9	9.3\|2436826\|33\|CP029678\|CRT	2436826-2436858	33	CP029678.1	1428265-1428297	2	0.939
CP029678_9	9.3\|2436826\|33\|CP029678\|CRT	2436826-2436858	33	CP029678.1	2712646-2712678	2	0.939

1. spacer 4.1|895586|34|CP029678|CRISPRCasFinder matches to position: 1428310-1428343, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

2. spacer 4.1|895586|34|CP029678|CRISPRCasFinder matches to position: 1517501-1517534, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

3. spacer 9.2|2436767|36|CP029678|CRT matches to position: 1220078-1220113, mismatch: 0, identity: 1.0

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttctttttgaaattctcta	Protospacer
************************************

4. spacer 3.1|852263|26|CP029678|CRISPRCasFinder matches to position: 815200-815225, mismatch: 1, identity: 0.962

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgcctgcttctgtgttggggccccg	Protospacer
***** ********************

5. spacer 3.1|852263|26|CP029678|CRISPRCasFinder matches to position: 2877996-2878021, mismatch: 1, identity: 0.962

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
************.*************

6. spacer 3.1|852263|26|CP029678|CRISPRCasFinder matches to position: 2878052-2878077, mismatch: 1, identity: 0.962

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctttgttggggccccg	Protospacer
************ *************

7. spacer 5.1|1002161|26|CP029678|CRT matches to position: 1002105-1002130, mismatch: 1, identity: 0.962

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacacagaggctggtgg	Protospacer
***********************.**

8. spacer 5.3|1002275|26|CP029678|CRT matches to position: 852319-852344, mismatch: 1, identity: 0.962

cggggccccaacacagaagctggcga	CRISPR spacer
cggggccccaacacagaagctgacga	Protospacer
**********************.***

9. spacer 7.1|2077842|33|CP029678|CRISPRCasFinder matches to position: 852299-852331, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

10. spacer 7.1|2077842|33|CP029678|CRISPRCasFinder matches to position: 1220134-1220166, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

11. spacer 7.1|2077842|33|CP029678|CRISPRCasFinder matches to position: 1428265-1428297, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

12. spacer 7.1|2077842|33|CP029678|CRISPRCasFinder matches to position: 1742773-1742805, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattatagtaagctgacttttcgtcagcttctg	Protospacer
****** **************************

13. spacer 7.1|2077842|33|CP029678|CRISPRCasFinder matches to position: 2712646-2712678, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

14. spacer 9.2|2436767|36|CP029678|CRT matches to position: 1921220-1921255, mismatch: 1, identity: 0.972

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaattctcta	Protospacer
************************.***********

15. spacer 3.1|852263|26|CP029678|CRISPRCasFinder matches to position: 815256-815281, mismatch: 2, identity: 0.923

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgcctgcttctatgttggggccccg	Protospacer
***** ******.*************

16. spacer 3.1|852263|26|CP029678|CRISPRCasFinder matches to position: 1002105-1002130, mismatch: 2, identity: 0.923

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccaccagcctctgtgttggggccccg	Protospacer
**.*****.*****************

17. spacer 5.1|1002161|26|CP029678|CRT matches to position: 815200-815225, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacacagaagcaggcgg	Protospacer
*****************.** *****

18. spacer 5.1|1002161|26|CP029678|CRT matches to position: 2877996-2878021, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
*************.***.********

19. spacer 5.1|1002161|26|CP029678|CRT matches to position: 2878052-2878077, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacaaagaagctggcgg	Protospacer
************* ***.********

20. spacer 5.3|1002275|26|CP029678|CRT matches to position: 393419-393444, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggcga	CRISPR spacer
cggggccccaacaaagaagctgacga	Protospacer
************* ********.***

21. spacer 7.1|2077842|33|CP029678|CRISPRCasFinder matches to position: 1517547-1517579, mismatch: 2, identity: 0.939

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcatcttctg	Protospacer
******.******************* ******

22. spacer 9.1|2436711|33|CP029678|CRT matches to position: 852299-852331, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

23. spacer 9.1|2436711|33|CP029678|CRT matches to position: 1220134-1220166, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

24. spacer 9.1|2436711|33|CP029678|CRT matches to position: 1428265-1428297, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

25. spacer 9.1|2436711|33|CP029678|CRT matches to position: 1517547-1517579, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcatcttctg	Protospacer
********** ***************.******

26. spacer 9.1|2436711|33|CP029678|CRT matches to position: 2712646-2712678, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

27. spacer 9.2|2436767|36|CP029678|CRT matches to position: 1742712-1742747, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaattctcta	Protospacer
*******.****************.***********

28. spacer 9.2|2436767|36|CP029678|CRT matches to position: 2088645-2088680, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcctttcgaaattctcta	Protospacer
********************.***.***********

29. spacer 9.3|2436826|33|CP029678|CRT matches to position: 852299-852331, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

30. spacer 9.3|2436826|33|CP029678|CRT matches to position: 1220134-1220166, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

31. spacer 9.3|2436826|33|CP029678|CRT matches to position: 1428265-1428297, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

32. spacer 9.3|2436826|33|CP029678|CRT matches to position: 2712646-2712678, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP029678_5	5.4\|1002331\|53\|CP029678\|CRT	1002331-1002383	53	MG543995	Staphylococcus phage UPMK_1, partial genome	76246-76298	4	0.925
CP029678_3	3.1\|852263\|26\|CP029678\|CRISPRCasFinder	852263-852288	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808
CP029678_3	3.1\|852263\|26\|CP029678\|CRISPRCasFinder	852263-852288	26	NZ_CP034332	Tabrizicola piscis strain K13M18 plasmid unnamed4, complete sequence	3359-3384	5	0.808
CP029678_3	3.1\|852263\|26\|CP029678\|CRISPRCasFinder	852263-852288	26	NZ_CP022605	Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence	715511-715536	5	0.808
CP029678_5	5.3\|1002275\|26\|CP029678\|CRT	1002275-1002300	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808
CP029678_7	7.1\|2077842\|33\|CP029678\|CRISPRCasFinder	2077842-2077874	33	NC_021536	Synechococcus phage S-IOM18 genomic sequence	159745-159777	10	0.697

1. spacer 5.4|1002331|53|CP029678|CRT matches to MG543995 (Staphylococcus phage UPMK_1, partial genome) position: , mismatch: 4, identity: 0.925

ggtgggacgacgaaataaattttgcgaaaatatcatttctgtcccactcccaa	CRISPR spacer
ggtgggacgacgaaataaattttgagaaactatcatttctgtcccactccctt	Protospacer
************************ **** *********************

2. spacer 3.1|852263|26|CP029678|CRISPRCasFinder matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
acgccagcttctgtgttgaggcctta	Protospacer
 *****************.****...

3. spacer 3.1|852263|26|CP029678|CRISPRCasFinder matches to NZ_CP034332 (Tabrizicola piscis strain K13M18 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctgtgtctgggcctac	Protospacer
****************. *****.

4. spacer 3.1|852263|26|CP029678|CRISPRCasFinder matches to NZ_CP022605 (Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctgtgtttggccctga	Protospacer
***************** ** **. .

5. spacer 5.3|1002275|26|CP029678|CRT matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

cggggccccaacacagaagctggcga	CRISPR spacer
taaggcctcaacacagaagctggcgt	Protospacer
...****.*****************

6. spacer 7.1|2077842|33|CP029678|CRISPRCasFinder matches to NC_021536 (Synechococcus phage S-IOM18 genomic sequence) position: , mismatch: 10, identity: 0.697

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
ttttatcgtaaggtgagttttcgtcaagcacct	Protospacer
. ********** *** *********. . *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

35339 : 78798

Staphylococcus_phage(50.0%)

integrase,transposase

attL 35280:35296|attR 75565:75581

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
35280:35296	attL	NA	NA	NA	NA
AWQ95430.1\|35339_36014_-\|transposase	transposase IS66 family protein	A0A0N9RU54	Staphylococcus_phage	2.6e-127	99.1
AWQ93824.1\|36271_36439_+	HMG-CoA synthase domain protein	NA	NA	NA	NA
AWQ93585.1\|37275_38019_+	glycerophosphoryl diester phosphodiesterase family protein	NA	NA	NA	NA
AWQ95682.1\|38115_38544_+	maoC like domain protein	NA	NA	NA	NA
AWQ93910.1\|38589_40596_-	penicillin-binding protein 2'	NA	NA	NA	NA
AWQ94783.1\|40695_41682_+	peptidase M48 family protein	NA	NA	NA	NA
AWQ93071.1\|41644_41914_+	hypothetical protein	NA	NA	NA	NA
AWQ94416.1\|41904_43428_-\|transposase	transposase DDE domain protein	A0ZS58	Staphylococcus_virus	1.6e-209	75.2
AWQ95010.1\|43563_44070_-	hypothetical protein	NA	NA	NA	NA
AWQ94140.1\|44084_44396_-	hypothetical protein	NA	NA	NA	NA
AWQ94820.1\|44482_44833_-	hypothetical protein	NA	NA	NA	NA
AWQ94089.1\|45354_46983_-	ogr/Delta-like zinc finger family protein	A0A0S2SXR4	Bacillus_phage	5.4e-46	31.4
AWQ93265.1\|47004_48354_-	recombinase family protein	Q9T200	Bacillus_phage	1.4e-18	24.8
AWQ94231.1\|48587_50375_-	hypothetical protein	NA	NA	NA	NA
AWQ95030.1\|50374_50665_-	hypothetical protein	NA	NA	NA	NA
AWQ93012.1\|50803_51853_+	putative actin depolymerizing protein	NA	NA	NA	NA
AWQ93532.1\|52470_53961_+	divergent AAA domain protein	NA	NA	NA	NA
AWQ95583.1\|54333_54507_-	putative rhodanese-like protein	NA	NA	NA	NA
AWQ93353.1\|54584_55589_-	metallo-beta-lactamase superfamily protein	NA	NA	NA	NA
AWQ94609.1\|55707_55845_+	hypothetical protein	NA	NA	NA	NA
AWQ93076.1\|55841_56213_+	HNH endonuclease family protein	NA	NA	NA	NA
AWQ95745.1\|56341_56962_+	hypothetical protein	NA	NA	NA	NA
AWQ94751.1\|57878_58049_-	hypothetical protein	NA	NA	NA	NA
AWQ94921.1\|58450_59416_+	HNH endonuclease family protein	NA	NA	NA	NA
AWQ94150.1\|59512_59704_+	hypothetical protein	NA	NA	NA	NA
AWQ94856.1\|59795_60125_+	hypothetical protein	NA	NA	NA	NA
AWQ94349.1\|60201_60561_-	tic20-like family protein	NA	NA	NA	NA
AWQ94702.1\|61131_61941_-\|integrase	integrase core domain protein	A0A0N9SIX5	Staphylococcus_phage	6.4e-56	94.8
AWQ95563.1\|61959_62142_+	hypothetical protein	NA	NA	NA	NA
AWQ94722.1\|62452_62950_-	acetyltransferase family protein	NA	NA	NA	NA
AWQ93205.1\|63137_63266_-	hypothetical protein	NA	NA	NA	NA
AWQ93440.1\|63447_64575_+	alcohol dehydrogenase GroES-like domain protein	A0A2K9L7I1	Tupanvirus	6.9e-16	30.9
AWQ95503.1\|64829_65054_-	hypothetical protein	NA	NA	NA	NA
AWQ93146.1\|65067_65571_-	hypothetical protein	NA	NA	NA	NA
AWQ94401.1\|65586_65898_-	hypothetical protein	NA	NA	NA	NA
AWQ93553.1\|65984_66335_-	hypothetical protein	NA	NA	NA	NA
AWQ93874.1\|67318_68143_+\|integrase	integrase core domain protein	A0A0N9SIX5	Staphylococcus_phage	2.9e-64	89.4
AWQ95516.1\|68242_69172_-	carbamate kinase	NA	NA	NA	NA
AWQ95260.1\|69191_70190_-	ornithine carbamoyltransferase	NA	NA	NA	NA
AWQ95661.1\|70227_70917_-	HTH-type transcriptional regulator ArcR	NA	NA	NA	NA
AWQ94816.1\|70958_72380_-	arginine-ornithine antiporter	NA	NA	NA	NA
AWQ94275.1\|72465_73701_-	arginine deiminase	NA	NA	NA	NA
AWQ94914.1\|73969_74416_-	arginine repressor, C-terminal domain protein	NA	NA	NA	NA
AWQ95744.1\|74917_75349_+	universal stress family protein	NA	NA	NA	NA
AWQ93436.1\|75425_75578_-	putative cadmium-transporting ATPase domain protein	NA	NA	NA	NA
AWQ93314.1\|75621_75867_+\|transposase	putative transposase	A0A0N9RU54	Staphylococcus_phage	1.9e-32	98.5
75565:75581	attR	NA	NA	NA	NA
AWQ93587.1\|75929_76295_+	DDE domain protein	A0A0N9RU54	Staphylococcus_phage	1.3e-61	95.9
AWQ95360.1\|76482_77298_+	alpha/beta hydrolase fold family protein	NA	NA	NA	NA
AWQ95475.1\|77784_78798_+\|transposase	transposase IS116/IS110/IS902 family protein	A0A1X9I619	Streptococcus_phage	6.0e-51	38.0

DBSCAN-SWA_2

783891 : 791711

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ95058.1\|783891_784947_-	histidine protein kinase SaeS	A0A1V0SGX0	Hokovirus	2.1e-14	30.0
AWQ93237.1\|784946_785633_-	response regulator	NA	NA	NA	NA
AWQ94003.1\|785607_786081_-	doxX family protein	NA	NA	NA	NA
AWQ93891.1\|786422_786863_-	electron transfer DM13 family protein	NA	NA	NA	NA
AWQ93836.1\|787142_787727_-	putative membrane protein	NA	NA	NA	NA
AWQ93234.1\|787825_788539_-	7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
AWQ94590.1\|788542_788962_-	queuosine biosynthesis protein QueD	S4U060	uncultured_phage	6.3e-07	28.7
AWQ93557.1\|788963_789632_-	queuosine biosynthesis protein QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
AWQ94599.1\|789982_790576_+	glutamine amidotransferase of anthranilate synthase/aminodeoxychorismate synthase family protein	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
AWQ95166.1\|790559_791711_+	chorismate binding enzyme family protein	A0A0B5J984	Pandoravirus	1.6e-23	35.7

DBSCAN-SWA_3

803683 : 818414

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ94217.1\|803683_804742_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
AWQ94182.1\|805092_805635_+	putative 5'(3')-deoxyribonucleotidase	NA	NA	NA	NA
AWQ95739.1\|806258_807176_-	putative lipid kinase	A0A1V0SBJ0	Catovirus	3.7e-07	22.0
AWQ95108.1\|807445_808951_-	H+ symporter family protein	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
AWQ93751.1\|809291_809792_-	7-cyano-7-deazaguanine reductase	E7DN65	Pneumococcus_phage	5.9e-52	71.5
AWQ95352.1\|809811_810678_-	eamA-like transporter family protein	NA	NA	NA	NA
AWQ93980.1\|811478_811877_+	nrdI protein	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
AWQ95456.1\|811839_813945_+	ribonucleoside-diphosphate reductase, alpha subunit	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
AWQ94197.1\|814062_815034_+	ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
AWQ94680.1\|815741_816713_+	fecCD transport family protein	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
AWQ95183.1\|816699_817656_+	fecCD transport family protein	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
AWQ93451.1\|817652_818414_+	ABC transporter family protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6

DBSCAN-SWA_4

897124 : 964377

Staphylococcus_phage(61.63%)

tail,terminase,holin,capsid,head,portal,integrase

attL 921092:921151|attR 964850:964939

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ93049.1\|897124_898150_+	methionine import ATP-binding protein MetN 2	G9BWD6	Planktothrix_phage	1.2e-27	36.8
AWQ95480.1\|898184_898838_+	methionine import system permease protein MetP	NA	NA	NA	NA
AWQ93778.1\|898855_899677_+	NLPA lipofamily protein	NA	NA	NA	NA
AWQ94670.1\|899819_901040_-\|integrase	phage integrase family protein	Q4ZE80	Staphylococcus_phage	2.9e-100	47.5
AWQ94458.1\|901127_901856_-	toxin beta-grasp domain protein	A0EX09	Staphylococcus_phage	1.2e-21	31.8
AWQ95683.1\|901879_902608_-	toxin beta-grasp domain protein	A0EX09	Staphylococcus_phage	1.6e-26	34.1
AWQ95339.1\|902624_903083_-	hypothetical protein	A0A2I6PEK4	Staphylococcus_phage	4.3e-65	82.1
AWQ93989.1\|903094_903427_-	helix-turn-helix family protein	A0A1J0MFC1	Staphylococcus_phage	1.6e-37	74.5
AWQ93188.1\|903619_903883_+	helix-turn-helix family protein	A0A2H4J9X2	uncultured_Caudovirales_phage	4.1e-36	94.8
AWQ95027.1\|903875_904148_+	putative pathogenicity island DNA-binding protein	Q4ZE77	Staphylococcus_phage	4.8e-40	88.9
AWQ93206.1\|904159_904333_+	pathogenicity island family protein	NA	NA	NA	NA
AWQ94885.1\|904299_904503_+	putative pathogenicity island protein	A0A1W6JQF4	Staphylococcus_phage	2.0e-30	98.5
AWQ95286.1\|904504_904888_+	putative pathogenicity island protein	A0A1W6JQI7	Staphylococcus_phage	4.4e-63	96.9
AWQ94761.1\|904888_905137_+	hypothetical protein	Q4ZE75	Staphylococcus_phage	1.4e-22	58.6
AWQ94036.1\|905228_907601_+	phage/plasmid primase, P4 family, C-terminal domain protein	A0A2H4JCU9	uncultured_Caudovirales_phage	9.8e-137	39.3
AWQ94634.1\|908271_908616_+	putative interference protein with phage growth	A0A1W6JQD5	Staphylococcus_phage	9.4e-41	65.2
AWQ94789.1\|908840_909047_+	hypothetical protein	NA	NA	NA	NA
AWQ94310.1\|909033_910092_+\|capsid	phage capsid family protein	A0A0K2CZ99	Paenibacillus_phage	3.6e-14	26.6
AWQ94335.1\|910275_910767_+\|terminase	putative terminase small subunit	A0A2H4JB26	uncultured_Caudovirales_phage	7.9e-25	40.5
AWQ93933.1\|911195_912164_+	abi-like family protein	A0A0H4U080	Erysipelothrix_phage	5.9e-24	27.3
AWQ93858.1\|912398_912953_-	putative penicillin binding protein	A0A1W6JQE5	Staphylococcus_phage	4.8e-71	76.1
AWQ94704.1\|913986_914181_+	hypothetical protein	NA	NA	NA	NA
AWQ94028.1\|914413_915265_-	hypothetical protein	NA	NA	NA	NA
AWQ94917.1\|915592_916354_+	feS assembly ATPase SufC	A0A1V0SE00	Indivirus	4.4e-06	23.3
AWQ95576.1\|916451_917759_+	feS assembly protein SufD	NA	NA	NA	NA
AWQ93732.1\|917873_919115_+	putative cysteine desulfurase	Q2XUY6	environmental_halophage	1.1e-110	44.5
AWQ95393.1\|919104_919569_+	SUF system FeS assembly protein, NifU family	NA	NA	NA	NA
AWQ93544.1\|919719_921117_+	feS assembly protein SufB	NA	NA	NA	NA
921092:921151	attL	NA	NA	NA	NA
AWQ94540.1\|921184_922234_-\|integrase	phage integrase family protein	A0A0F6N3M4	Staphylococcus_phage	9.1e-204	100.0
AWQ94004.1\|922295_922811_-	hypothetical protein	I1W624	Staphylococcus_phage	1.5e-37	100.0
AWQ95041.1\|922814_923315_-	hypothetical protein	B7T094	Staphylococcus_virus	2.6e-71	99.4
AWQ93415.1\|923367_923553_-	hypothetical protein	E9LT71	Staphylococcus_phage	4.3e-24	100.0
AWQ93186.1\|923613_923799_-	hypothetical protein	Q9G041	Staphylococcus_virus	5.1e-25	98.4
AWQ95569.1\|923795_923942_-	hypothetical protein	U5U441	Staphylococcus_phage	4.3e-19	100.0
AWQ94472.1\|923953_924664_-	helix-turn-helix family protein	Q9MBT4	Staphylococcus_prophage	2.6e-130	100.0
AWQ93100.1\|924834_925074_+	helix-turn-helix family protein	Q9MBT3	Staphylococcus_prophage	8.0e-39	100.0
AWQ93245.1\|925086_925530_+	putative phage transcriptional regulator	A0A0H3U2S6	Staphylococcus_phage	2.0e-75	99.3
AWQ95297.1\|925544_925688_+	hypothetical protein	W5R8I6	Staphylococcus_phage	2.5e-16	100.0
AWQ93640.1\|925677_925887_-	hypothetical protein	W5R9J5	Staphylococcus_phage	1.2e-30	100.0
AWQ95135.1\|925943_926657_+	hypothetical protein	A0A059T7N7	Staphylococcus_phage	2.6e-125	97.9
AWQ95050.1\|927011_927272_+	hypothetical protein	A9CR59	Staphylococcus_phage	9.9e-43	98.8
AWQ94470.1\|927286_927766_+	siphovirus Gp157 family protein	Q9MBS3	Staphylococcus_prophage	8.1e-83	100.0
AWQ95566.1\|927765_928404_+	ERF superfamily protein	Q9MBS2	Staphylococcus_prophage	1.7e-115	100.0
AWQ95026.1\|928403_928832_+	single-stranded DNA-binding protein ssb	A0A2H4JHI1	uncultured_Caudovirales_phage	1.2e-53	93.0
AWQ94328.1\|928845_929520_+	hypothetical protein	Q4ZD97	Staphylococcus_virus	2.8e-129	100.0
AWQ95676.1\|929625_930483_-	hypothetical protein	Q4ZBL8	Staphylococcus_phage	9.5e-159	100.0
AWQ93087.1\|930547_931303_+	conserved phage family protein	W5R8N2	Staphylococcus_phage	2.6e-115	98.0
AWQ95617.1\|931312_932092_+	AAA domain family protein	W5RAN3	Staphylococcus_phage	1.2e-144	100.0
AWQ93390.1\|932085_932247_+	hypothetical protein	D2JGK6	Staphylococcus_phage	4.5e-22	100.0
AWQ93895.1\|932259_932481_+	hypothetical protein	A7TWN4	Staphylococcus_phage	1.3e-35	100.0
AWQ93371.1\|932491_932896_+	hypothetical protein	A7TWN5	Staphylococcus_phage	7.1e-72	100.0
AWQ95144.1\|932900_933086_+	hypothetical protein	A0A068A236	Staphylococcus_phage	7.8e-26	95.1
AWQ95149.1\|933086_933272_+	PVL ORF-50-like family protein	R4II61	Staphylococcus_phage	1.5e-29	100.0
AWQ95035.1\|933272_933449_+	PVL ORF-50-like family protein	B7T0B4	Staphylococcus_virus	1.1e-21	87.9
AWQ95055.1\|933448_933703_+	hypothetical protein	Q6R831	Staphylococcus_virus	1.3e-42	100.0
AWQ93379.1\|933708_933951_+	phage family protein	A0A2K9VBX5	Staphylococcus_phage	1.1e-40	100.0
AWQ93549.1\|933964_934369_+	hypothetical protein	A0A0E3T8H9	Staphylococcus_phage	1.2e-71	98.5
AWQ93603.1\|934365_934713_+	yopX family protein	D2JGL4	Staphylococcus_phage	5.9e-59	100.0
AWQ95749.1\|935010_935259_+	hypothetical protein	A0A2K9VBU0	Staphylococcus_phage	1.6e-37	97.6
AWQ93944.1\|935251_935782_+	dUTPase family protein	I1W653	Staphylococcus_phage	3.5e-95	98.3
AWQ94322.1\|935818_936106_+	hypothetical protein	Q4ZAB6	Staphylococcus_virus	4.4e-44	96.8
AWQ94311.1\|936098_936335_+	hypothetical protein	A0A2I6PEM4	Staphylococcus_phage	2.0e-34	94.9
AWQ93122.1\|936327_936714_+	hypothetical protein	Q4ZBK1	Staphylococcus_phage	1.6e-60	91.4
AWQ95403.1\|936710_936884_+	transcriptional activator RinB family protein	A9CR97	Staphylococcus_phage	7.5e-23	98.2
AWQ93570.1\|936884_937031_+	hypothetical protein	A0A059T5A8	Staphylococcus_phage	2.2e-15	100.0
AWQ95412.1\|937054_937477_+	phage transcriptional regulator, RinA family protein	A0A0F6N3E5	Staphylococcus_phage	1.2e-74	100.0
AWQ95450.1\|937664_938159_+\|terminase	terminase small subunit	A0A0F6N3K6	Staphylococcus_phage	2.3e-88	99.4
AWQ93120.1\|938161_939457_+\|terminase	phage terminase, large subunit, PBSX family	A0A0F6N3L3	Staphylococcus_phage	2.8e-255	99.3
AWQ94615.1\|939467_941003_+\|portal	phage portal protein, SPP1 family	A1KX25	Staphylococcus_virus	4.6e-289	99.2
AWQ93510.1\|941009_942005_+\|head	phage head morphogenesis, SPP1 gp7 family domain protein	E0Y3K7	Staphylococcus_virus	4.2e-182	98.5
AWQ94527.1\|942077_942248_+	hypothetical protein	Q4ZDF2	Staphylococcus_virus	3.3e-23	100.0
AWQ95523.1\|942382_942997_+	hypothetical protein	I1W646	Staphylococcus_phage	2.9e-40	100.0
AWQ94407.1\|943010_943985_+\|capsid	phage major capsid protein, HK97 family	Q4ZDM8	Staphylococcus_virus	2.2e-183	100.0
AWQ93341.1\|944006_944294_+	hypothetical protein	Q8SDU4	Staphylococcus_phage	1.4e-45	98.9
AWQ94991.1\|944302_944635_+\|head,tail	phage gp6-like head-tail connector family protein	E0Y3L2	Staphylococcus_virus	1.6e-53	99.1
AWQ94949.1\|944933_945281_+	hypothetical protein	A0A0F6N3F5	Staphylococcus_phage	4.1e-60	100.0
AWQ95409.1\|945292_945676_+	hypothetical protein	E0Y3L5	Staphylococcus_virus	1.7e-67	97.6
AWQ93616.1\|945694_946276_+\|tail	phage major tail protein, TP901-1 family	A0A0F6N3L8	Staphylococcus_phage	2.4e-105	99.5
AWQ94501.1\|946338_946704_+	phage family protein	A0A0F6N4J9	Staphylococcus_phage	3.6e-59	100.0
AWQ94838.1\|946733_947078_+	hypothetical protein	A0A0F6N3F7	Staphylococcus_phage	2.5e-57	100.0
AWQ93716.1\|947094_950562_+	putative membrane protein	Q4ZDU6	Staphylococcus_virus	9.8e-271	97.7
AWQ94282.1\|950574_951522_+\|tail	phage tail family protein	I1W635	Staphylococcus_phage	4.7e-183	99.7
AWQ94050.1\|951530_953432_+\|tail	prophage endopeptidase tail family protein	Q4ZDD8	Staphylococcus_virus	0.0e+00	99.8
AWQ95384.1\|953446_955357_+	putative minor structural protein	A0EWM6	Staphylococcus_virus	0.0e+00	100.0
AWQ93832.1\|955356_957180_+	hypothetical protein	Q4ZBH7	Staphylococcus_virus	0.0e+00	99.8
AWQ95738.1\|957179_957557_+	hypothetical protein	A0A0F6N3G4	Staphylococcus_phage	1.5e-60	100.0
AWQ95453.1\|957559_957733_+	hypothetical protein	A0A0F6N3L7	Staphylococcus_phage	6.6e-27	100.0
AWQ95618.1\|957773_958073_+	hypothetical protein	A0A0F6N3M6	Staphylococcus_phage	1.3e-46	99.0
AWQ95187.1\|958209_960108_+	CHAP domain protein	E0Y3M7	Staphylococcus_virus	0.0e+00	99.7
AWQ93758.1\|960120_961293_+	hypothetical protein	A0EWN2	Staphylococcus_virus	8.4e-198	100.0
AWQ93983.1\|961298_961694_+	hypothetical protein	Q4ZBP5	Staphylococcus_phage	2.7e-68	100.0
AWQ93747.1\|961749_962187_+\|holin	holin, phage phi LC3 family	A0EWV0	Staphylococcus_virus	2.0e-72	99.3
AWQ94013.1\|962167_963613_+	CHAP domain protein	A0EWV1	Staphylococcus_virus	3.4e-294	99.2
AWQ93291.1\|963880_964009_+	hypothetical protein	A0A0F6N3H2	Staphylococcus_phage	1.1e-15	100.0
AWQ95707.1\|964191_964377_+	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.7e-26	100.0
964850:964939	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1121027 : 1129500

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ93193.1\|1121027_1121510_+	phosphoribosylaminoimidazole carboxylase, catalytic subunit	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
AWQ94682.1\|1121496_1122621_+	N5-carboxyaminoimidazole ribonucleotide synthase	NA	NA	NA	NA
AWQ93901.1\|1122624_1123329_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
AWQ93620.1\|1123328_1123592_+	phosphoribosylformylglycinamidine synthase, purS protein	NA	NA	NA	NA
AWQ93267.1\|1123593_1124265_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
AWQ93217.1\|1124257_1126447_+	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	1.0e-140	39.7
AWQ94640.1\|1126425_1127910_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
AWQ93005.1\|1127902_1128931_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
AWQ93718.1\|1128933_1129500_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_6

1386197 : 1392241

Staphylococcus_phage(66.67%)

head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ94744.1\|1386197_1386395_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	1.7e-10	48.4
AWQ95605.1\|1387095_1387308_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	3.1e-18	71.0
AWQ93900.1\|1387601_1387808_+	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	1.3e-13	59.7
AWQ93112.1\|1389046_1389232_+	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.4e-19	78.7
AWQ93095.1\|1389976_1390228_+	hypothetical protein	NA	NA	NA	NA
AWQ94496.1\|1390273_1390858_+\|head	phage head morphogenesis, SPP1 gp7 family domain protein	Q4ZE35	Staphylococcus_virus	2.0e-30	72.0
AWQ94596.1\|1390978_1391227_+	hypothetical protein	NA	NA	NA	NA
AWQ93132.1\|1391653_1391770_+	hypothetical protein	NA	NA	NA	NA
AWQ95601.1\|1391778_1391904_+	hypothetical protein	NA	NA	NA	NA
AWQ93643.1\|1392106_1392241_+	hypothetical protein	Q4ZE35	Staphylococcus_virus	2.9e-14	76.2

DBSCAN-SWA_7

1474448 : 1509497

Staphylococcus_prophage(16.67%)

lysis,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ94531.1\|1474448_1474745_+\|transposase	transposase DDE domain protein	Q9MBP7	Staphylococcus_prophage	6.2e-41	89.7
AWQ93982.1\|1474879_1475782_-	conserved virulence factor B	NA	NA	NA	NA
AWQ95471.1\|1475928_1477530_+	ABC transporter family protein	A0A1V0SKJ1	Klosneuvirus	5.5e-51	25.7
AWQ95289.1\|1478389_1479595_+	aspartate kinase domain protein	NA	NA	NA	NA
AWQ93004.1\|1479658_1480648_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
AWQ95482.1\|1480649_1481537_+	dihydrodipicolinate synthase	NA	NA	NA	NA
AWQ94478.1\|1481533_1482256_+	dihydrodipicolinate reductase	NA	NA	NA	NA
AWQ93978.1\|1482282_1483002_+	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase	NA	NA	NA	NA
AWQ94152.1\|1483144_1484296_+	amidohydrolase family protein	NA	NA	NA	NA
AWQ93094.1\|1484300_1485386_+	alanine racemase 2	NA	NA	NA	NA
AWQ95210.1\|1485375_1486641_+	diaminopimelate decarboxylase	A0A0P0YM38	Yellowstone_lake_phycodnavirus	6.2e-13	23.2
AWQ93717.1\|1486880_1487282_-	putative membrane protein	NA	NA	NA	NA
AWQ95700.1\|1487478_1487679_-	cold shock protein CspA	Q9AZD3	Lactococcus_phage	8.4e-18	66.2
AWQ94010.1\|1487849_1488158_-	hypothetical protein	NA	NA	NA	NA
AWQ95069.1\|1488320_1488590_+	acylphosphatase family protein	NA	NA	NA	NA
AWQ93128.1\|1488614_1489238_+\|lysis	5-bromo-4-chloroindolyl phosphate hydrolysis family protein	NA	NA	NA	NA
AWQ95592.1\|1489269_1490406_+	telA-like protein	A0A291I9K4	Lactobacillus_phage	7.4e-34	28.3
AWQ94357.1\|1490461_1490644_-\|transposase	putative transposase	Q9MBP7	Staphylococcus_prophage	5.1e-22	88.3
AWQ93498.1\|1490673_1491066_-\|transposase	transposase DDE domain protein	A0A146ICT8	Staphylococcus_phage	7.7e-15	93.2
AWQ95497.1\|1491418_1492762_-	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
AWQ94216.1\|1492986_1494873_-	cobalamin biosynthesis CobT VWA domain protein	NA	NA	NA	NA
AWQ93233.1\|1494886_1495678_-	ATPase associated with various cellular activities family protein	R4TG24	Halovirus	2.1e-11	28.2
AWQ94530.1\|1495858_1496062_-	putative hypothetical protein YozC	NA	NA	NA	NA
AWQ93413.1\|1496090_1496900_-	putative lactoylglutathione lyase	NA	NA	NA	NA
AWQ94812.1\|1497479_1498748_-	dihydrolipoyllysine-residue succinyltransferase	NA	NA	NA	NA
AWQ93403.1\|1498761_1501560_-	oxoglutarate dehydrogenase (succinyl-transferring), E1 component	NA	NA	NA	NA
AWQ95296.1\|1501843_1503199_-	signal transduction histidine-protein kinase ArlS	A0A1V0SGX0	Hokovirus	3.5e-14	27.8
AWQ94899.1\|1503195_1503855_-	response regulator	W8CYM9	Bacillus_phage	1.1e-34	33.8
AWQ94287.1\|1504768_1505254_+\|transposase	transposase IS200 like family protein	A0A1P8BMC0	Lactococcus_phage	4.9e-19	35.4
AWQ94858.1\|1505384_1505999_-	PAP2 superfamily protein	NA	NA	NA	NA
AWQ94035.1\|1506015_1507086_-	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	NA	NA	NA	NA
AWQ93599.1\|1507097_1507607_-	acetyltransferase domain protein	NA	NA	NA	NA
AWQ95001.1\|1508006_1509497_-\|protease	putative CtpA-like serine protease	A0A0R6PIZ1	Moraxella_phage	2.3e-22	30.5

DBSCAN-SWA_8

1571273 : 1658409

105

Staphylococcus_phage(83.12%)

tail,terminase,holin,tRNA,capsid,head,portal,integrase,protease

attL 1607636:1607656|attR 1653529:1653549

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ93243.1\|1571273_1572566_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.9e-54	30.0
AWQ95080.1\|1572887_1575581_-	hypothetical protein	A0A1X9I5C8	Streptococcus_phage	8.2e-47	34.4
AWQ95374.1\|1575604_1576576_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
AWQ94592.1\|1576562_1577765_-\|head	poly A polymerase head domain protein	H7BUW3	unidentified_phage	3.2e-35	42.5
AWQ95143.1\|1577769_1578912_-	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
AWQ94538.1\|1579152_1579470_-	mazG nucleotide pyrophosphohydrolase domain protein	NA	NA	NA	NA
AWQ95754.1\|1579806_1580505_-	neutral zinc metallopeptidase family protein	NA	NA	NA	NA
AWQ93821.1\|1580558_1581146_-	hypothetical protein	NA	NA	NA	NA
AWQ94817.1\|1581135_1581711_-	hypothetical protein	G3MAV7	Bacillus_virus	2.7e-08	27.2
AWQ95586.1\|1581724_1582969_-	TPR repeat family protein	NA	NA	NA	NA
AWQ94805.1\|1582975_1584274_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
AWQ94735.1\|1584283_1585348_-	3-dehydroquinate synthase	NA	NA	NA	NA
AWQ94721.1\|1585373_1586540_-	chorismate synthase	A0A291AU41	Pandoravirus	7.6e-34	32.1
AWQ95007.1\|1587334_1587784_-	nucleoside diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
AWQ93896.1\|1587875_1588835_-	heptaprenyl diphosphate synthase component 2	A0A1V0SE37	Indivirus	1.3e-10	24.4
AWQ94607.1\|1588836_1589562_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
AWQ95186.1\|1589564_1590137_-	heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 family protein	NA	NA	NA	NA
AWQ93101.1\|1590567_1590840_-	DNA-binding protein HU	A7KV42	Bacillus_phage	4.2e-28	73.3
AWQ93810.1\|1591010_1592009_-	NAD-dependent glycerol-3-phosphate dehydrogenase family protein	NA	NA	NA	NA
AWQ93098.1\|1592025_1593336_-	ribosome-associated GTPase EngA	NA	NA	NA	NA
AWQ94085.1\|1593557_1594733_-	30S ribosomal protein S1	NA	NA	NA	NA
AWQ94515.1\|1595297_1595414_-	hypothetical protein	NA	NA	NA	NA
AWQ94636.1\|1595444_1596104_-	cytidylate kinase	NA	NA	NA	NA
AWQ94719.1\|1596180_1597149_+	asparaginase family protein	NA	NA	NA	NA
AWQ93613.1\|1597263_1598250_-	pyridine nucleotide-disulfide oxidoreductase family protein	NA	NA	NA	NA
AWQ95446.1\|1598410_1598527_-	hypothetical protein	NA	NA	NA	NA
AWQ94798.1\|1598651_1600112_-	elastin-binding protein EbpS	NA	NA	NA	NA
AWQ94913.1\|1600264_1601644_-	ATP-dependent DNA helicase, RecQ family protein	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	2.9e-56	33.6
AWQ94762.1\|1601633_1602587_-	hypothetical protein	NA	NA	NA	NA
AWQ94556.1\|1602694_1602943_+	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
AWQ94171.1\|1603048_1603594_-	riboflavin transporter RibU	NA	NA	NA	NA
AWQ93657.1\|1603872_1603992_-	hypothetical protein	NA	NA	NA	NA
AWQ93562.1\|1604190_1605105_-	hypothetical protein	NA	NA	NA	NA
AWQ95036.1\|1605119_1605326_-	hypothetical protein	NA	NA	NA	NA
AWQ94421.1\|1605318_1606257_-	hypothetical protein	NA	NA	NA	NA
AWQ94833.1\|1606313_1607231_-	hypothetical protein	NA	NA	NA	NA
AWQ93230.1\|1607321_1607507_-	hypothetical protein	A0ZS61	Staphylococcus_virus	1.7e-25	100.0
1607636:1607656	attL	NA	NA	NA	NA
AWQ95022.1\|1607755_1608733_-	lukF-PV	A0A2I6PEU3	Staphylococcus_phage	7.5e-184	100.0
AWQ95580.1\|1608734_1609673_-	gamma-hemolysin component C	A0A2I6PER8	Staphylococcus_phage	3.7e-180	100.0
AWQ95550.1\|1610062_1611517_-	N-acetylmuramoyl-L-alanine amidase family protein	A0A2I6PET7	Staphylococcus_phage	5.7e-289	100.0
AWQ94359.1\|1611527_1611830_-\|holin	holin, SPP1 family	A0A2I6PET6	Staphylococcus_phage	7.0e-48	100.0
AWQ93505.1\|1611965_1612265_-	hypothetical protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
AWQ94423.1\|1612310_1612475_-	hypothetical protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
AWQ93673.1\|1612467_1612857_-	hypothetical protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
AWQ94101.1\|1612856_1614323_-	hypothetical protein	A0A2I6PES7	Staphylococcus_phage	1.5e-273	100.0
AWQ93724.1\|1614322_1616233_-	putative minor structural protein	A0A2I6PEQ9	Staphylococcus_phage	0.0e+00	100.0
AWQ93080.1\|1616248_1616539_-	putative phage protein	U5U457	Staphylococcus_phage	2.1e-49	100.0
AWQ94162.1\|1616538_1618122_-\|tail	prophage endopeptidase tail family protein	A0A2I6PEQ5	Staphylococcus_phage	9.3e-309	100.0
AWQ94714.1\|1618130_1618955_-\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
AWQ95585.1\|1618954_1625155_-\|tail	phage tail tape measure protein, TP901 family, core region	A0A1X9IGU9	Staphylococcus_phage	0.0e+00	99.7
AWQ93274.1\|1625168_1625327_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
AWQ95227.1\|1625368_1625719_-	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
AWQ94707.1\|1625776_1626232_-	bacterial Ig-like domain family protein	A0A2I6PER6	Staphylococcus_phage	5.7e-78	100.0
AWQ94396.1\|1626323_1626965_-\|tail	phage major tail, phi13 family protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
AWQ95385.1\|1626999_1627395_-	hypothetical protein	A0A2I6PEQ4	Staphylococcus_phage	8.8e-67	100.0
AWQ94946.1\|1627395_1627797_-	hypothetical protein	A0A2I6PF54	Staphylococcus_phage	8.1e-68	100.0
AWQ95671.1\|1627793_1628126_-	hypothetical protein	A0A2I6PES3	Staphylococcus_phage	4.1e-57	100.0
AWQ94088.1\|1628137_1628416_-\|head,tail	phage gp6-like head-tail connector family protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
AWQ95091.1\|1628484_1629648_-\|capsid	phage major capsid protein, HK97 family	A0A2I6PEQ3	Staphylococcus_phage	1.2e-217	100.0
AWQ95199.1\|1629659_1630433_-\|protease	clp protease family protein	A0A2I6PEQ7	Staphylococcus_phage	2.4e-137	100.0
AWQ93750.1\|1630416_1631655_-\|portal	phage portal protein, HK97 family	A0A2I6PER5	Staphylococcus_phage	6.9e-235	100.0
AWQ93823.1\|1631659_1633351_-	phage Terminase family protein	A0A1X9IGU0	Staphylococcus_phage	0.0e+00	100.0
AWQ95535.1\|1633340_1633646_-\|terminase	phage terminase, small subunit	A0A2I6PEQ6	Staphylococcus_phage	2.9e-49	100.0
AWQ95702.1\|1633772_1634087_-	HNH endonuclease family protein	A0A2I6PEN4	Staphylococcus_phage	5.0e-57	100.0
AWQ93531.1\|1634243_1634681_-	phage transcriptional regulator, RinA family protein	A0A2I6PEN3	Staphylococcus_phage	7.9e-77	100.0
AWQ94875.1\|1634693_1636052_-	SNF2 family N-terminal domain protein	A0A1X9IH01	Staphylococcus_phage	2.8e-261	99.8
AWQ93595.1\|1636041_1636332_-	VRR-NUC domain protein	A0A2I6PE31	Staphylococcus_phage	6.5e-51	100.0
AWQ95093.1\|1636526_1636649_+	hypothetical protein	Q4ZCF9	Staphylococcus_virus	6.9e-15	95.0
AWQ93993.1\|1636672_1639120_-	virulence-associated E family protein	A0A2I6PEP4	Staphylococcus_phage	0.0e+00	100.0
AWQ94628.1\|1639407_1639608_-	hypothetical protein	A0A2I6PEP5	Staphylococcus_phage	4.9e-26	100.0
AWQ93030.1\|1639675_1639828_-	transcriptional activator RinB family protein	A0A2I6PEM5	Staphylococcus_phage	2.0e-19	100.0
AWQ94403.1\|1639824_1640211_-	hypothetical protein	A0A1X9IGZ2	Staphylococcus_phage	3.0e-64	100.0
AWQ95621.1\|1640203_1640440_-	hypothetical protein	A0A2I6PEM4	Staphylococcus_phage	2.8e-36	100.0
AWQ95020.1\|1640432_1640636_-	hypothetical protein	A0A2I6PEQ8	Staphylococcus_phage	3.4e-30	100.0
AWQ95376.1\|1640632_1640839_-	hypothetical protein	A0A2I6PEM9	Staphylococcus_phage	1.6e-19	100.0
AWQ95207.1\|1640875_1641412_-	dUTPase family protein	A0A2I6PEN6	Staphylococcus_phage	1.6e-95	100.0
AWQ94593.1\|1641404_1641653_-	hypothetical protein	A0A2I6PEP2	Staphylococcus_phage	1.4e-38	100.0
AWQ95096.1\|1641667_1641910_-	phage family protein	A0A2I6PEV3	Staphylococcus_phage	1.5e-40	100.0
AWQ94988.1\|1641924_1642125_-	hypothetical protein	A0A2I6PEM3	Staphylococcus_phage	2.5e-30	100.0
AWQ95448.1\|1642127_1642385_-	hypothetical protein	A0A2I6PEN5	Staphylococcus_phage	2.6e-43	100.0
AWQ94788.1\|1642384_1642786_-	PVL ORF-50-like family protein	A0A2I6PEL5	Staphylococcus_phage	1.2e-68	100.0
AWQ95174.1\|1642785_1642971_-	hypothetical protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
AWQ95011.1\|1642983_1644945_-	DNA polymerase A family protein	A0A2I6PEL4	Staphylococcus_phage	0.0e+00	100.0
AWQ94633.1\|1645003_1645561_-	hypothetical protein	A0A2I6PEP8	Staphylococcus_phage	1.8e-97	100.0
AWQ93973.1\|1645586_1646753_-	hypothetical protein	A0A2I6PEL9	Staphylococcus_phage	1.4e-221	100.0
AWQ94614.1\|1646749_1647112_-	hypothetical protein	A0A2I6PEM7	Staphylococcus_phage	3.7e-56	100.0
AWQ94677.1\|1647125_1647386_-	hypothetical protein	A0A2I6PEM2	Staphylococcus_phage	3.4e-43	100.0
AWQ93849.1\|1647390_1647693_-	hypothetical protein	A0A1X9IGX2	Staphylococcus_phage	2.4e-48	100.0
AWQ93565.1\|1647685_1648003_-	hypothetical protein	A0A2I6PEL3	Staphylococcus_phage	1.1e-35	100.0
AWQ95148.1\|1648268_1648532_-	homeo-like domain protein	A0A2I6PEL8	Staphylococcus_phage	2.5e-46	100.0
AWQ93468.1\|1648556_1648772_-	hypothetical protein	A0A2I6PEK7	Staphylococcus_phage	1.0e-32	100.0
AWQ95045.1\|1648839_1649058_+	hypothetical protein	A0A2I6PE22	Staphylococcus_phage	9.2e-34	98.6
AWQ95323.1\|1649054_1649231_-	hypothetical protein	A0A2I6PEL1	Staphylococcus_phage	8.8e-27	100.0
AWQ94632.1\|1649314_1649506_-	helix-turn-helix family protein	A0A2I6PEL6	Staphylococcus_phage	2.3e-28	100.0
AWQ94268.1\|1649666_1649996_+	bacteriophage CI repressor helix-turn-helix domain protein	A0A2I6PEN2	Staphylococcus_phage	3.2e-54	100.0
AWQ94128.1\|1650098_1650470_+	hypothetical protein	A0A2I6PEK4	Staphylococcus_phage	1.6e-65	99.2
AWQ94471.1\|1650487_1650922_+	putative translation initiation factor IF-2	A0A2I6PEM0	Staphylococcus_phage	3.6e-21	96.5
AWQ93119.1\|1650950_1651346_+	hypothetical protein	A0A2I6PEJ7	Staphylococcus_phage	3.8e-70	100.0
AWQ93383.1\|1651456_1651582_+	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	3.3e-12	100.0
AWQ95031.1\|1651578_1652193_-	hypothetical protein	A0A2I6PEZ0	Staphylococcus_phage	6.7e-106	100.0
AWQ93458.1\|1652318_1653524_+\|integrase	phage integrase family protein	A0A2I6PEN0	Staphylococcus_phage	7.7e-223	100.0
AWQ94621.1\|1653566_1654721_-	hypothetical protein	B5WZK7	Staphylococcus_phage	3.9e-115	97.7
1653529:1653549	attR	NA	NA	NA	NA
AWQ94526.1\|1654747_1655593_-	hypothetical protein	NA	NA	NA	NA
AWQ94510.1\|1655585_1656455_-	hypothetical protein	NA	NA	NA	NA
AWQ95382.1\|1656759_1658409_-	sensor protein SrrB	A0A1V0SGX0	Hokovirus	1.6e-21	33.6

DBSCAN-SWA_9

1714342 : 1722647

Staphylococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ93776.1\|1714342_1715128_-	ABC transporter family protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
AWQ94122.1\|1715253_1716144_-	putative endonuclease 4	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
AWQ94007.1\|1716153_1717500_-	DEAD/DEAH box helicase family protein	A0A1V0SIR5	Klosneuvirus	5.3e-55	33.7
AWQ94481.1\|1717613_1718714_-	NIF3 family protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
AWQ94520.1\|1718716_1719394_-	hypothetical protein	NA	NA	NA	NA
AWQ93176.1\|1719508_1720624_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
AWQ93439.1\|1720847_1722647_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.6e-54	36.0

DBSCAN-SWA_10

1791784 : 1800827

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ93416.1\|1791784_1792303_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
AWQ95067.1\|1792324_1794598_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-62	28.8
AWQ95043.1\|1794800_1797080_-	protein-export membrane protein SecD	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
AWQ95196.1\|1797354_1797615_-	preprotein translocase, YajC subunit	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
AWQ94630.1\|1797633_1798773_-\|tRNA	queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
AWQ94916.1\|1798795_1799821_-\|tRNA	tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
AWQ93653.1\|1799822_1800827_-	holliday junction DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_11

1926283 : 2043363

106

Staphylococcus_phage(86.76%)

bacteriocin,tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ93968.1\|1926283_1932844_-	sasC/Mrp/FmtB intercellular aggregation domain protein	A0A2H4PQU6	Staphylococcus_phage	2.0e-304	98.1
AWQ94277.1\|1933169_1933481_-	rhodanese-like domain protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
AWQ93269.1\|1933502_1935917_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.2
AWQ93092.1\|1936207_1937389_-	major Facilitator Superfamily protein	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
AWQ94191.1\|1937498_1938452_+	radical SAM superfamily protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
AWQ93220.1\|1938448_1939012_+	rRNA methylase family protein	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
AWQ93555.1\|1939131_1939533_-	HTH-type transcriptional regulator rot	NA	NA	NA	NA
AWQ93213.1\|1940052_1940277_-	hypothetical protein	Q9MBP7	Staphylococcus_prophage	4.5e-20	81.8
AWQ95411.1\|1940273_1940765_-	hypothetical protein	A0A146ICT8	Staphylococcus_phage	2.4e-74	91.6
AWQ94220.1\|1941111_1941939_-	alpha/beta hydrolase family protein	NA	NA	NA	NA
AWQ94123.1\|1942172_1943174_+	proline dehydrogenase family protein	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
AWQ93727.1\|1943295_1943760_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
AWQ93680.1\|1943772_1944954_-	riboflavin biosynthesis protein RibBA	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
AWQ95348.1\|1944964_1945597_-	riboflavin synthase, alpha subunit	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
AWQ94270.1\|1945603_1946647_-	riboflavin biosynthesis protein RibD	A0A2H4PQS8	Staphylococcus_phage	6.3e-197	99.4
AWQ95746.1\|1947127_1948630_-	FAD-NAD(P)-binding family protein	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
AWQ93871.1\|1949466_1950759_+	arsenite/antimonite efflux pump membrane family protein	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
AWQ95487.1\|1950776_1951172_+	arsenate reductase	A0A2H4PQT9	Staphylococcus_phage	6.3e-73	100.0
AWQ94166.1\|1951466_1952321_-	mannosyl-glycoendo-beta-N-acetylglucosaminidase family protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
AWQ94016.1\|1952596_1952821_-	hypothetical protein	NA	NA	NA	NA
AWQ94931.1\|1953019_1953490_+	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
AWQ93725.1\|1953902_1954046_+	hypothetical protein	NA	NA	NA	NA
AWQ95542.1\|1954032_1954476_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	8.6e-55	84.4
AWQ93437.1\|1954771_1955407_+\|protease	CAAX protease self-immunity family protein	NA	NA	NA	NA
AWQ94227.1\|1955846_1956560_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
AWQ94616.1\|1956819_1957122_+	putative membrane protein	NA	NA	NA	NA
AWQ94995.1\|1957377_1957743_+	crcB-like family protein	A0A2H4PQR0	Staphylococcus_phage	1.4e-58	99.2
AWQ95223.1\|1957739_1958093_+	crcB-like family protein	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
AWQ94494.1\|1958647_1959472_+\|transposase	transposase DDE domain protein	A0ZS58	Staphylococcus_virus	1.7e-125	98.2
AWQ94791.1\|1959504_1960113_+\|transposase	transposase DDE domain protein	A0ZS58	Staphylococcus_virus	1.3e-109	96.0
AWQ95300.1\|1960175_1961009_-	aldo/keto reductase family protein	A0A2H4PQR8	Staphylococcus_phage	9.6e-156	98.6
AWQ95341.1\|1961220_1962129_-	nuclease-related domain protein	A0A2H4PQQ8	Staphylococcus_phage	3.2e-136	98.7
AWQ93770.1\|1962253_1963447_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
AWQ93794.1\|1963817_1965410_+	phosphoenolpyruvate carboxykinase	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
AWQ95529.1\|1965545_1965908_-\|transposase	transposase IS200 like family protein	A0A1P8BMC0	Lactococcus_phage	1.8e-10	37.8
AWQ94225.1\|1966405_1967176_-	prolyl oligopeptidase family protein	A0A2H4PQM6	Staphylococcus_phage	7.3e-142	98.4
AWQ93729.1\|1967156_1967636_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	1.5e-84	98.7
AWQ93827.1\|1967695_1967953_+	putative membrane protein insertion efficiency factor	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
AWQ94280.1\|1967949_1968951_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	4.8e-186	97.6
AWQ94749.1\|1968955_1970434_-	O-succinylbenzoate-CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.0e-281	97.0
AWQ94855.1\|1970592_1971075_-	putative lipoprotein	A0A2H4PQN7	Staphylococcus_phage	2.5e-79	98.6
AWQ93144.1\|1971386_1972001_+	excalibur calcium-binding domain protein	A0A2H4PQM8	Staphylococcus_phage	9.5e-36	87.3
AWQ95507.1\|1972081_1973077_+	hypothetical protein	A0A2H4PQN2	Staphylococcus_phage	7.1e-73	96.4
AWQ95668.1\|1973152_1973308_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	4.7e-08	96.9
AWQ93663.1\|1973308_1973779_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	7.0e-63	80.1
AWQ94202.1\|1973819_1974164_+	hypothetical protein	A0A2H4PQN6	Staphylococcus_phage	6.3e-53	92.0
AWQ93712.1\|1974261_1974813_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.0e-20	94.1
AWQ95189.1\|1975030_1975600_-	hypothetical protein	A0A2H4PQN8	Staphylococcus_phage	2.3e-76	93.2
AWQ93276.1\|1975785_1975971_-	hypothetical protein	NA	NA	NA	NA
AWQ93976.1\|1975972_1976149_-	putative membrane protein	NA	NA	NA	NA
AWQ94360.1\|1976159_1976543_-	hypothetical protein	NA	NA	NA	NA
AWQ95039.1\|1977146_1977290_-\|transposase	transposase family protein	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0
AWQ95213.1\|1978159_1978537_-	hypothetical protein	NA	NA	NA	NA
AWQ95760.1\|1979057_1983170_-	NACHT domain protein	A0A2H4PQT3	Staphylococcus_phage	0.0e+00	100.0
AWQ94410.1\|1984019_1985219_-	type I restriction modification DNA specificity domain protein	A0A2H4PQP5	Staphylococcus_phage	5.5e-229	99.7
AWQ94509.1\|1985211_1986768_-	type I restriction-modification system, M subunit	A0A2H4PQP4	Staphylococcus_phage	2.3e-288	99.4
AWQ93791.1\|1987130_1987850_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.1e-131	100.0
AWQ94385.1\|1988000_1988717_-\|protease	serine protease SplF	A0A2H4PQN5	Staphylococcus_phage	1.1e-131	100.0
AWQ94600.1\|1988874_1989594_-\|protease	serine protease SplF	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
AWQ94388.1\|1989714_1990434_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.2e-130	99.2
AWQ94024.1\|1990491_1991214_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	2.4e-131	99.6
AWQ93948.1\|1991338_1992046_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	2.6e-130	100.0
AWQ95054.1\|1993009_1993576_+	hypothetical protein	A0A2H4PQH6	Staphylococcus_phage	3.3e-99	100.0
AWQ93963.1\|1994049_1994748_-	putative membrane protein	A0A2H4PQH0	Staphylococcus_phage	3.8e-113	94.4
AWQ95078.1\|1994744_1995506_-	lantibiotic protection ABC transporter permease subunit, MutE/EpiE family protein	A0A2H4PQH2	Staphylococcus_phage	4.4e-131	100.0
AWQ93523.1\|1995502_1996195_-	lantibiotic protection ABC transporter, ATP-binding subunit	A0A2H4PQG7	Staphylococcus_phage	6.2e-124	100.0
AWQ94234.1\|1996217_1997591_-	subtilase family protein	A0A2H4PQH1	Staphylococcus_phage	2.9e-258	100.0
AWQ94351.1\|1997600_1998119_-	epidermin decarboxylase	A0A2H4PQG9	Staphylococcus_phage	2.0e-95	100.0
AWQ95201.1\|1998134_1999379_-	lanthionine synthetase C-like family protein	A0A2H4PQH9	Staphylococcus_phage	5.1e-238	100.0
AWQ94205.1\|1999371_2002365_-\|bacteriocin	thiopeptide-type bacteriocin biosynthesis domain protein	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	97.3
AWQ94504.1\|2002429_2002573_-	lantibiotic gallidermin	A0A2H4PQH4	Staphylococcus_phage	5.3e-14	80.9
AWQ94105.1\|2003694_2004678_-	leucotoxin LukDv	A0A2H4PQH7	Staphylococcus_phage	2.3e-185	99.1
AWQ95435.1\|2004679_2005615_-	leucotoxin LukEv	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0
AWQ95308.1\|2006497_2006953_+	hypothetical protein	Q4ZCB9	Staphylococcus_virus	1.7e-61	76.8
AWQ93617.1\|2006965_2007607_+	hypothetical protein	A0A2H4PQI0	Staphylococcus_phage	1.1e-111	94.8
AWQ94147.1\|2010209_2010764_-	serine hydrolase family protein	NA	NA	NA	NA
AWQ95116.1\|2011086_2012487_-	protoporphyrinogen oxidase	NA	NA	NA	NA
AWQ94958.1\|2012510_2013434_-	ferrochelatase	NA	NA	NA	NA
AWQ93315.1\|2013491_2014529_-	uroporphyrinogen decarboxylase	NA	NA	NA	NA
AWQ94130.1\|2014791_2015295_+	signal transduction protein TRAP	NA	NA	NA	NA
AWQ95598.1\|2015418_2016642_-	bacterial ABC transporter EcsB family protein	NA	NA	NA	NA
AWQ95490.1\|2016634_2017375_-	ABC transporter family protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-24	29.8
AWQ93386.1\|2017508_2017931_+	protein hit	NA	NA	NA	NA
AWQ95658.1\|2018072_2018438_+	hypothetical protein	NA	NA	NA	NA
AWQ95178.1\|2019170_2019728_+	hypothetical protein	NA	NA	NA	NA
AWQ93957.1\|2019932_2020559_+	foldase protein PrsA	NA	NA	NA	NA
AWQ95567.1\|2020548_2020884_+	foldase protein PrsA 1	NA	NA	NA	NA
AWQ95241.1\|2021004_2021946_-	3'-5' exoribonuclease YhaM	NA	NA	NA	NA
AWQ94543.1\|2021942_2024879_-	AAA domain protein	NA	NA	NA	NA
AWQ95266.1\|2024868_2026065_-	calcineurin-like phosphoesterase superfamily domain protein	NA	NA	NA	NA
AWQ94674.1\|2026836_2027181_-	hypothetical protein	A0A1X9I5Y8	Streptococcus_phage	7.5e-06	29.7
AWQ94365.1\|2027249_2028374_-	hypothetical protein	NA	NA	NA	NA
AWQ95111.1\|2028552_2029017_-	helix-turn-helix family protein	NA	NA	NA	NA
AWQ95160.1\|2029372_2029996_-	response regulator	NA	NA	NA	NA
AWQ93621.1\|2030017_2031130_-	histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein	NA	NA	NA	NA
AWQ94998.1\|2031292_2032114_+	RNA pseudouridylate synthase family protein	NA	NA	NA	NA
AWQ93322.1\|2032576_2033962_-	fumarate hydratase, class II	NA	NA	NA	NA
AWQ94087.1\|2034157_2034553_-	putative membrane protein	NA	NA	NA	NA
AWQ94778.1\|2035329_2035482_-	hypothetical protein	NA	NA	NA	NA
AWQ93141.1\|2035506_2036106_-	glucosamine-6-phosphate isomerase family protein	NA	NA	NA	NA
AWQ95392.1\|2036264_2036735_-\|tRNA	tRNA (cytidine(34)-2'-O)-methyltransferase	NA	NA	NA	NA
AWQ94451.1\|2036739_2037867_-	epoxyqueuosine reductase	NA	NA	NA	NA
AWQ94034.1\|2038017_2038740_-	recF/RecN/SMC N terminal domain protein	G9BWD6	Planktothrix_phage	1.3e-36	42.7
AWQ93266.1\|2038732_2040190_-	amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein	NA	NA	NA	NA
AWQ93575.1\|2040447_2041509_-	phosphotransferase system, EIIC family protein	NA	NA	NA	NA
AWQ93160.1\|2042001_2043363_+\|transposase	transposase family protein	NA	NA	NA	NA

DBSCAN-SWA_12

2132742 : 2190981

Staphylococcus_phage(97.1%)

tail,terminase,holin,capsid,head,portal,integrase,protease

attL 2152167:2152184|attR 2177098:2177115

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ93025.1\|2132742_2132940_+	phospholipase C domain protein	A0A1P8L6A7	Staphylococcus_phage	3.4e-27	100.0
AWQ93850.1\|2133311_2133491_+	putative membrane protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
AWQ93373.1\|2133870_2134062_+	putative membrane protein	M9NS66	Staphylococcus_phage	1.7e-23	100.0
AWQ95077.1\|2134114_2134465_-	complement inhibitor	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
AWQ93784.1\|2135149_2135599_+	chemotaxis inhibitory protein	A0A1P8L6A8	Staphylococcus_phage	1.1e-78	100.0
AWQ93073.1\|2135693_2135990_-	bacterial SH3 domain protein	A0A1P8L6B4	Staphylococcus_phage	1.3e-51	100.0
AWQ94635.1\|2136678_2137170_-	staphylokinase	A0A1X9H028	Staphylococcus_phage	9.5e-87	100.0
AWQ93252.1\|2137360_2138116_-	CHAP domain protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
AWQ94806.1\|2138127_2138382_-\|holin	holin, phage phi LC3 family	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
AWQ94994.1\|2138593_2138728_-	putative membrane protein	D2JLG3	Staphylococcus_phage	9.3e-13	100.0
AWQ93155.1\|2138919_2139216_-	hypothetical protein	D2JLG2	Staphylococcus_phage	2.9e-46	100.0
AWQ95639.1\|2139273_2139561_-	hypothetical protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
AWQ94106.1\|2139607_2139760_-	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
AWQ94255.1\|2139749_2143535_-	phage minor structural, N-terminal region domain protein	A0A1X9H0H3	Staphylococcus_phage	0.0e+00	98.5
AWQ94075.1\|2143550_2145035_-\|tail	phage tail family protein	A0A0H3U501	Staphylococcus_phage	2.0e-297	100.0
AWQ95190.1\|2145031_2149561_-\|tail	phage tail tape measure protein, TP901 family, core region	A0A1X9H084	Staphylococcus_phage	0.0e+00	95.0
AWQ95229.1\|2149617_2149752_-	hypothetical protein	A0A2I6PDX7	Staphylococcus_phage	9.6e-18	100.0
AWQ93818.1\|2149805_2150156_-	hypothetical protein	A0A0H3U503	Staphylococcus_phage	1.3e-58	100.0
AWQ93464.1\|2150205_2150346_-	bacterial Ig-like domain family protein	A0A2I6PDK6	Staphylococcus_phage	7.2e-16	97.8
AWQ93994.1\|2150471_2151116_-\|tail	phage major tail, phi13 family protein	A0A0H3U4E6	Staphylococcus_phage	6.5e-120	100.0
AWQ94490.1\|2151520_2151925_-	hypothetical protein	A0A0H3U2V1	Staphylococcus_phage	8.7e-70	100.0
AWQ94567.1\|2151921_2152284_-\|head,tail	phage head-tail joining family protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
2152167:2152184	attL	NA	NA	NA	NA
AWQ95512.1\|2152267_2152552_-\|head,tail	phage gp6-like head-tail connector family protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
AWQ93610.1\|2152541_2152826_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
AWQ94658.1\|2152845_2153991_-\|capsid	phage major capsid protein, HK97 family	G4KNQ3	Staphylococcus_phage	9.6e-215	100.0
AWQ93490.1\|2154014_2154752_-\|protease	clp protease family protein	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
AWQ93307.1\|2154735_2155923_-\|portal	phage portal protein, HK97 family	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
AWQ94557.1\|2155938_2157600_-	phage Terminase family protein	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
AWQ93686.1\|2157596_2157941_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
AWQ93992.1\|2158070_2158370_-	HNH endonuclease family protein	A0EWY8	Staphylococcus_phage	4.6e-52	100.0
AWQ94133.1\|2158601_2159018_-	phage transcriptional regulator, RinA family protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
AWQ95732.1\|2159045_2159246_-	hypothetical protein	A0A2I6PDV9	Staphylococcus_phage	1.4e-28	100.0
AWQ93472.1\|2159245_2159395_-	transcriptional activator RinB family protein	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
AWQ95648.1\|2159391_2159778_-	hypothetical protein	W5R986	Staphylococcus_phage	3.0e-64	100.0
AWQ94347.1\|2159774_2159981_-	hypothetical protein	A0A0H3U2R7	Staphylococcus_phage	1.3e-29	100.0
AWQ95042.1\|2159977_2160223_-	putative membrane protein	A0A2I6PDW7	Staphylococcus_phage	5.0e-36	100.0
AWQ93796.1\|2160259_2160793_-	dUTP diphosphatase family protein	A0A0H3U2T1	Staphylococcus_phage	1.6e-95	100.0
AWQ94740.1\|2160785_2161028_-	hypothetical protein	A0A2I6PF40	Staphylococcus_phage	3.7e-36	100.0
AWQ95182.1\|2161017_2161254_-	hypothetical protein	A0A0H3U313	Staphylococcus_phage	5.3e-35	100.0
AWQ93300.1\|2161246_2161612_-	acetyltransferase family protein	A0A0H3U4X7	Staphylococcus_phage	1.1e-52	96.4
AWQ94918.1\|2161626_2161791_-	phage family protein	A0A0H3U4B0	Staphylococcus_phage	1.7e-24	98.1
AWQ94260.1\|2161872_2162241_-	PVL ORF-50-like family protein	A0A0H3U2T3	Staphylococcus_phage	2.0e-49	100.0
AWQ93200.1\|2162253_2162658_-	endodeoxyribonuclease RusA family protein	A0A0H3U2W2	Staphylococcus_phage	1.4e-72	100.0
AWQ94574.1\|2162666_2162885_-	hypothetical protein	A0A2I6PDG4	Staphylococcus_phage	1.0e-37	100.0
AWQ95557.1\|2162891_2163785_-	dnaD domain protein	A0A1P8L6F0	Staphylococcus_phage	3.2e-141	100.0
AWQ93789.1\|2163814_2164285_-	single-stranded DNA-binding family protein	A0A0H3U4B5	Staphylococcus_phage	4.4e-81	100.0
AWQ95708.1\|2164285_2164771_-	beta-lactamase superfamily domain protein	A0A0H3U2T4	Staphylococcus_phage	4.2e-87	100.0
AWQ95581.1\|2164983_2165904_-	recombinase, phage RecT family protein	A0A2I6PDH5	Staphylococcus_phage	2.3e-166	100.0
AWQ95325.1\|2165905_2167849_-	AAA domain protein	A0A2I6PDH3	Staphylococcus_phage	0.0e+00	94.7
AWQ93773.1\|2168129_2168390_-	hypothetical protein	A0A0H3U2T6	Staphylococcus_phage	6.8e-44	100.0
AWQ93816.1\|2168429_2168690_-	hypothetical protein	A0A0H3U2W4	Staphylococcus_phage	9.3e-41	100.0
AWQ93859.1\|2168942_2169263_-	hypothetical protein	A0A0H3U4C3	Staphylococcus_phage	1.5e-56	100.0
AWQ94170.1\|2169333_2169552_+	putative phiSLT ORF78-like protein	A0A0H3U2T9	Staphylococcus_phage	7.0e-34	98.6
AWQ94984.1\|2169548_2169725_-	hypothetical protein	A0A2I6PEL1	Staphylococcus_phage	8.8e-27	100.0
AWQ95419.1\|2169740_2170493_-	phage antirepressor KilAC domain protein	A0A0H3U319	Staphylococcus_phage	5.6e-139	100.0
AWQ93812.1\|2170543_2170873_+	hypothetical protein	A0A0H3U4Z1	Staphylococcus_phage	4.6e-53	100.0
AWQ94598.1\|2171092_2171356_-	helix-turn-helix family protein	A0A2I6PF09	Staphylococcus_phage	7.2e-41	100.0
AWQ95085.1\|2171488_2172202_+	peptidase S24-like family protein	M9NUL0	Staphylococcus_phage	1.2e-130	100.0
AWQ95751.1\|2172217_2173150_+	exonuclease family protein	A0A2I6PEZ7	Staphylococcus_phage	5.7e-173	100.0
AWQ93644.1\|2173155_2173497_+	hypothetical protein	A0A2I6PF04	Staphylococcus_phage	4.6e-56	100.0
AWQ93521.1\|2173700_2173883_+	hypothetical protein	A0A0H3U4Z4	Staphylococcus_phage	4.1e-27	100.0
AWQ93127.1\|2173960_2174674_+	pemK-like family protein	A0A1X9H026	Staphylococcus_phage	5.0e-129	100.0
AWQ93387.1\|2174864_2175902_+\|integrase	integrase	A0A1X9H022	Staphylococcus_phage	3.8e-178	99.7
AWQ95659.1\|2175958_2176783_+	sphingomyelin phosphodiesterase	A0A1P8L6H7	Staphylococcus_phage	6.8e-162	100.0
AWQ94782.1\|2177020_2178037_-	hypothetical protein	A0A2I6PER8	Staphylococcus_phage	1.1e-25	29.0
2177098:2177115	attR	NA	NA	NA	NA
AWQ95461.1\|2178058_2179114_-	hypothetical protein	A0A1X9IGW5	Staphylococcus_phage	2.8e-35	34.3
AWQ93749.1\|2179548_2180772_+	putative succinyl-diaminopimelate desuccinylase	NA	NA	NA	NA
AWQ93954.1\|2181143_2181989_-	leucine carboxyl methyltransferase family protein	NA	NA	NA	NA
AWQ95218.1\|2182050_2182962_-	periplasmic binding family protein	NA	NA	NA	NA
AWQ94342.1\|2183122_2184430_+	ktr system potassium uptake protein B	NA	NA	NA	NA
AWQ94086.1\|2185282_2185726_-	acetyltransferase family protein	NA	NA	NA	NA
AWQ94261.1\|2185890_2186232_-	putative membrane protein	NA	NA	NA	NA
AWQ94242.1\|2186585_2187176_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.1e-97	95.8
AWQ93294.1\|2188086_2189703_-	chaperonin GroL	A0A240F779	uncultured_virus	3.4e-157	54.7
AWQ93338.1\|2189778_2190063_-	10 kDa chaperonin	A0A221S386	uncultured_virus	4.7e-14	46.2
AWQ93539.1\|2190237_2190981_+\|protease	CAAX protease self-immunity family protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP029677

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP029678

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection