CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
CP029825	Burkholderia sp. JP2-270 chromosome 2, complete sequence	0 crisprs	DinG,cas3,csa3,c2c9_V-U4	0	3
CP029828	Burkholderia sp. JP2-270 plasmid p2, complete sequence	0 crisprs	csa3,RT	0	5
CP029826	Burkholderia sp. JP2-270 chromosome 3, complete sequence	0 crisprs	RT,PD-DExK,cas14j	0	101
CP029827	Burkholderia sp. JP2-270 plasmid p1, complete sequence	1 crisprs	NA	1	0
CP029824	Burkholderia sp. JP2-270 chromosome 1, complete sequence	6 crisprs	WYL,Cas14u_CAS-V,DEDDh,cas3,DinG,csa3	2	5

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

10926 : 90470

Bacillus_phage(11.11%)

transposase,tRNA,plate,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV01415.1\|10926_12630_+\|protease	serine protease	A0A217EQY2	Bacillus_phage	3.6e-24	35.9
AWV01416.1\|12717_13377_+	hypothetical protein	NA	NA	NA	NA
AWV01417.1\|14472_15426_+	hypothetical protein	NA	NA	NA	NA
AWV01418.1\|15412_15955_+	glycoside hydrolase family 19 protein	A0A059VA40	Pseudomonas_phage	4.0e-38	56.2
AWV01419.1\|15896_17006_+	hypothetical protein	NA	NA	NA	NA
AWV01420.1\|17284_18067_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
AWV01421.1\|18065_18317_+	hypothetical protein	NA	NA	NA	NA
AWV01422.1\|18675_19323_+	OsmY domain-containing protein	NA	NA	NA	NA
AWV01423.1\|19363_19873_+\|tRNA	glutamyl-tRNA amidotransferase	NA	NA	NA	NA
AWV01424.1\|19906_21814_+	cell division protein FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	3.8e-107	43.3
AWV01425.1\|23890_24826_+	1-phosphofructokinase family hexose kinase	NA	NA	NA	NA
AWV01426.1\|24943_25732_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
AWV01427.1\|25724_26972_+	GTP-binding protein	NA	NA	NA	NA
AWV01428.1\|26917_29293_+	serine hydrolase	NA	NA	NA	NA
AWV01429.1\|29720_31394_-	electron transfer flavoprotein-ubiquinone oxidoreductase	NA	NA	NA	NA
AWV01430.1\|31414_32053_-	hypothetical protein	NA	NA	NA	NA
AWV01431.1\|32049_32988_-	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
AWV01432.1\|32984_33764_-	electron transfer flavoprotein subunit alpha	NA	NA	NA	NA
AWV01433.1\|33789_34974_-	FAD-binding oxidoreductase	NA	NA	NA	NA
AWV01434.1\|35155_36121_+	LysR family transcriptional regulator	NA	NA	NA	NA
AWV01435.1\|36138_36948_+	N-formylglutamate deformylase	NA	NA	NA	NA
AWV01436.1\|37151_37754_-	XRE family transcriptional regulator	NA	NA	NA	NA
AWV03977.1\|38031_39384_+	type III glutamate--ammonia ligase	NA	NA	NA	NA
AWV01437.1\|39396_40305_+	amidophosphoribosyltransferase	NA	NA	NA	NA
AWV01438.1\|40292_40982_+	protein glxC	NA	NA	NA	NA
AWV01439.1\|41008_42370_+	FMN-binding glutamate synthase family protein	NA	NA	NA	NA
AWV01440.1\|42595_43996_+	ammonia channel protein	NA	NA	NA	NA
AWV01441.1\|44451_44841_-	gamma carboxymuconolactone decarboxylase	NA	NA	NA	NA
AWV01442.1\|44856_46269_-	cytosine permease	NA	NA	NA	NA
AWV01443.1\|46385_47855_-	carnitine dehydratase	NA	NA	NA	NA
AWV01444.1\|47867_48905_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
AWV01445.1\|48916_49852_-	flavin reductase	NA	NA	NA	NA
AWV01446.1\|49853_50672_-	alpha/beta hydrolase	NA	NA	NA	NA
AWV01447.1\|50640_51243_-	amino acid synthesis family protein	NA	NA	NA	NA
AWV01448.1\|51353_51644_+	DUF1330 domain-containing protein	NA	NA	NA	NA
AWV01449.1\|51708_52464_+	GntR family transcriptional regulator	NA	NA	NA	NA
AWV03978.1\|52665_53622_+	flavin reductase	NA	NA	NA	NA
AWV01450.1\|53772_54813_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AWV01451.1\|54948_55833_+	ABC transporter permease	NA	NA	NA	NA
AWV01452.1\|55834_56635_+	ABC transporter permease	NA	NA	NA	NA
AWV01453.1\|56646_57753_+	polyamine ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.3e-27	35.3
AWV01454.1\|57764_58472_+	GntR family transcriptional regulator	NA	NA	NA	NA
AWV01455.1\|58704_60165_+	succinate-semialdehyde dehydrogenase (NADP(+))	NA	NA	NA	NA
AWV03979.1\|60307_61579_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.7e-39	42.8
AWV01456.1\|62885_67502_-	type IV secretion protein Rhs	A0A2H4JFP5	uncultured_Caudovirales_phage	2.3e-25	36.0
AWV01457.1\|67516_68782_-	hypothetical protein	NA	NA	NA	NA
AWV01458.1\|68797_71002_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	5.3e-44	28.3
AWV01459.1\|70998_73650_-	type VI secretion system ATPase TssH	A0A248SJW6	Salicola_phage	1.3e-73	29.5
AWV01460.1\|73662_74781_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
AWV01461.1\|74777_76649_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
AWV03980.1\|76653_77163_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
AWV01462.1\|77246_77738_-	Hcp1 family type VI secretion system effector	NA	NA	NA	NA
AWV01463.1\|77821_79330_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
AWV01464.1\|79322_79877_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
AWV01465.1\|79950_81066_-	type VI secretion system protein TssA	NA	NA	NA	NA
AWV01466.1\|81052_83365_-	serine/threonine protein kinase	S4VYW6	Pandoravirus	3.5e-06	26.3
AWV01467.1\|83418_84114_-	type VI secretion system-associated protein TagF	NA	NA	NA	NA
AWV01468.1\|84095_87722_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
AWV01469.1\|87723_89058_-	type VI secretion system protein TssL	NA	NA	NA	NA
AWV01470.1\|89072_90470_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

DBSCAN-SWA_2

731981 : 790451

Burkholderia_phage(90.48%)

holin,head,portal,tail,terminase,capsid,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV01967.1\|731981_733679_+	recombinase family protein	Q3HQV4	Burkholderia_phage	1.6e-261	81.7
AWV04036.1\|734067_735054_+	DUF262 domain-containing protein	A0A0R6PKN1	Moraxella_phage	4.2e-17	28.8
AWV01968.1\|735185_735989_+	hypothetical protein	NA	NA	NA	NA
AWV01969.1\|736247_736952_-	DUF159 family protein	A0A1S5NTJ1	Burkholderia_phage	1.7e-116	83.2
AWV01970.1\|737006_737498_+	hypothetical protein	C7BGE3	Burkholderia_phage	7.3e-87	92.0
AWV01971.1\|737524_738421_-	hypothetical protein	C7BGE2	Burkholderia_phage	2.9e-150	91.3
AWV01972.1\|738523_739315_-	DNA adenine methylase	C7BGE1	Burkholderia_phage	1.0e-154	98.9
AWV01973.1\|739453_739936_-	hypothetical protein	C7BGD9	Burkholderia_phage	6.7e-53	71.2
AWV01974.1\|739932_740382_-	peptidase M15	C7BGD8	Burkholderia_phage	1.1e-73	96.0
AWV01975.1\|740384_740669_-\|holin	holin	C7BGD7	Burkholderia_phage	1.0e-40	97.9
AWV01976.1\|740726_741443_-	hypothetical protein	C7BGD6	Burkholderia_phage	2.3e-89	64.7
AWV01977.1\|741442_741751_-	hypothetical protein	C7BGD5	Burkholderia_phage	1.2e-34	65.7
AWV01978.1\|741750_745659_-	host specificity protein	C7BGD4	Burkholderia_phage	0.0e+00	95.2
AWV01979.1\|745655_746219_-\|tail	tail assembly protein	C7BGD3	Burkholderia_phage	1.9e-91	96.3
AWV01980.1\|746215_746968_-\|tail	phage tail protein	C7BGD2	Burkholderia_phage	2.8e-146	95.6
AWV01981.1\|747017_747701_-\|tail	phage minor tail protein L	C7BGD1	Burkholderia_phage	3.3e-122	92.1
AWV01982.1\|747705_749097_-	hypothetical protein	C7BGD0	Burkholderia_phage	6.8e-98	58.5
AWV01983.1\|749204_749543_-\|tail	phage tail protein	C7BGC9	Burkholderia_phage	1.6e-56	92.0
AWV01984.1\|749542_753643_-\|tail	phage tail tape measure protein	C7BGC8	Burkholderia_phage	0.0e+00	93.1
AWV04037.1\|753656_753935_-\|tail	phage tail protein	Q4FAS6	Burkholderia_phage	2.4e-39	91.3
AWV01985.1\|753931_754399_-\|tail	phage tail protein	C7BGC7	Burkholderia_phage	1.0e-74	89.7
AWV01986.1\|754426_754891_-\|tail	phage tail protein	Q4FAS7	Burkholderia_phage	3.7e-72	91.6
AWV01987.1\|754950_755295_-	hypothetical protein	Q3HQT5	Burkholderia_phage	3.6e-40	75.4
AWV01988.1\|755291_755714_-	hypothetical protein	C7BGH3	Burkholderia_phage	5.7e-64	92.1
AWV01989.1\|755706_756033_-\|head,tail	head-tail adaptor protein	C7BGH2	Burkholderia_phage	3.2e-54	98.1
AWV01990.1\|756043_756628_-	hypothetical protein	C7BGH1	Burkholderia_phage	5.8e-99	94.8
AWV01991.1\|756678_757944_-\|capsid	phage major capsid protein	C7BGH0	Burkholderia_phage	2.5e-232	97.4
AWV01992.1\|758012_758816_-\|protease	Clp protease ClpP	C7BGG9	Burkholderia_phage	9.1e-111	90.4
AWV01993.1\|758781_760071_-\|portal	phage portal protein	C7BGG8	Burkholderia_phage	2.6e-216	85.3
AWV01994.1\|760067_761732_-\|terminase	terminase large subunit	C7BGG7	Burkholderia_phage	2.7e-298	89.8
AWV01995.1\|761776_762280_-	hypothetical protein	C7BGG6	Burkholderia_phage	7.4e-87	91.0
AWV01996.1\|762475_762844_-	HNH endonuclease	C7BGG5	Burkholderia_phage	2.5e-63	94.3
AWV01997.1\|762844_763057_-	hypothetical protein	NA	NA	NA	NA
AWV01998.1\|763219_763618_-	hypothetical protein	C7BGG3	Burkholderia_phage	1.1e-64	94.7
AWV01999.1\|763628_764669_-	helix-turn-helix domain-containing protein	C7BGG2	Burkholderia_phage	3.6e-160	82.7
AWV02000.1\|764714_766082_-	replicative DNA helicase	C7BGG1	Burkholderia_phage	9.9e-251	98.9
AWV02001.1\|766109_766616_-	hypothetical protein	C7BGG0	Burkholderia_phage	9.2e-85	97.0
AWV02002.1\|766706_766907_+	hypothetical protein	C7BGF9	Burkholderia_phage	9.3e-33	90.9
AWV02003.1\|767087_767327_-	hypothetical protein	K7PHA1	Enterobacteria_phage	1.5e-05	33.8
AWV02004.1\|767413_767818_+	hypothetical protein	NA	NA	NA	NA
AWV02005.1\|767814_768075_-	hypothetical protein	NA	NA	NA	NA
AWV02006.1\|768407_768641_+	hypothetical protein	NA	NA	NA	NA
AWV02007.1\|768782_768989_+	hypothetical protein	C7BGF3	Burkholderia_phage	6.9e-23	83.8
AWV02008.1\|768992_769283_+	hypothetical protein	Q546W6	Burkholderia_phage	4.8e-22	56.7
AWV02009.1\|769304_769859_+	hypothetical protein	NA	NA	NA	NA
AWV02010.1\|769873_770368_+	PRTRC system protein C	NA	NA	NA	NA
AWV02011.1\|770364_770550_+	hypothetical protein	NA	NA	NA	NA
AWV02012.1\|770546_771608_+	hypothetical protein	NA	NA	NA	NA
AWV02013.1\|771604_772318_+	PRTRC system protein B	NA	NA	NA	NA
AWV04038.1\|772332_773124_+	PRTRC system protein A	NA	NA	NA	NA
AWV02014.1\|773120_773501_+	hypothetical protein	NA	NA	NA	NA
AWV02015.1\|773485_774262_+	PRTRC system ThiF family protein	NA	NA	NA	NA
AWV02016.1\|774728_775016_+	hypothetical protein	Q3HQV5	Burkholderia_phage	3.0e-24	60.2
AWV02017.1\|775408_775747_+	hypothetical protein	NA	NA	NA	NA
AWV04039.1\|775805_776678_-	phosphatidylinositol diacylglycerol-lyase	NA	NA	NA	NA
AWV02018.1\|776729_777752_+	LacI family transcriptional regulator	NA	NA	NA	NA
AWV02019.1\|777784_778645_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
AWV02020.1\|778641_779511_-	sugar ABC transporter permease	NA	NA	NA	NA
AWV02021.1\|779545_780784_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
AWV02022.1\|780971_782180_-	porin	NA	NA	NA	NA
AWV02023.1\|782313_783252_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AWV02024.1\|783320_783908_-	DUF3156 domain-containing protein	NA	NA	NA	NA
AWV02025.1\|783904_785407_-	APC family amino acid permease	NA	NA	NA	NA
AWV02026.1\|785594_786935_-	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	1.7e-21	26.4
AWV02027.1\|787005_788508_-	NAD-dependent phenylacetaldehyde dehydrogenase	NA	NA	NA	NA
AWV02028.1\|788671_789412_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
AWV02029.1\|789569_790451_-\|protease	metalloprotease	A0A1I9SA48	Rhodococcus_phage	6.2e-36	39.3

DBSCAN-SWA_3

2496902 : 2553621

uncultured_virus(28.57%)

plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV03373.1\|2496902_2497707_+\|transposase	IS5 family transposase	NA	NA	NA	NA
AWV03374.1\|2497931_2498159_-	hypothetical protein	NA	NA	NA	NA
AWV03375.1\|2498719_2499271_+	PAAR domain-containing protein	NA	NA	NA	NA
AWV03376.1\|2499267_2500215_+	glycine zipper family protein	NA	NA	NA	NA
AWV03377.1\|2501568_2502828_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.1e-44	45.0
AWV03378.1\|2503243_2503540_+	hypothetical protein	NA	NA	NA	NA
AWV03379.1\|2503801_2505043_-	amidohydrolase family protein	NA	NA	NA	NA
AWV03380.1\|2505055_2506372_-	MFS transporter	Q6JIH2	Burkholderia_virus	1.5e-131	57.0
AWV03381.1\|2506495_2507407_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	8.0e-71	46.4
AWV03382.1\|2507606_2507843_+	hypothetical protein	NA	NA	NA	NA
AWV03383.1\|2508942_2509353_+	TIGR02594 family protein	A0A249Y3Q7	Serratia_phage	1.2e-29	43.3
AWV03384.1\|2509493_2510126_+	glutathione transferase	NA	NA	NA	NA
AWV03385.1\|2510273_2510897_+	lysine transporter LysE	NA	NA	NA	NA
AWV03386.1\|2510916_2511099_+	hypothetical protein	NA	NA	NA	NA
AWV04186.1\|2511241_2512513_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.7e-39	42.8
AWV03387.1\|2512531_2513965_-	RND transporter	NA	NA	NA	NA
AWV03388.1\|2513975_2515550_-	EmrB/QacA family drug resistance transporter	NA	NA	NA	NA
AWV03389.1\|2515563_2516658_-	HlyD family secretion protein	NA	NA	NA	NA
AWV03390.1\|2516722_2517154_-	MarR family transcriptional regulator	NA	NA	NA	NA
AWV03391.1\|2517261_2518182_-	LysR family transcriptional regulator	NA	NA	NA	NA
AWV03392.1\|2518293_2518722_+	MarR family transcriptional regulator	NA	NA	NA	NA
AWV03393.1\|2518946_2520194_+	aconitase subunit 1	NA	NA	NA	NA
AWV03394.1\|2520186_2520636_+	aconitase subunit 2	NA	NA	NA	NA
AWV03395.1\|2520655_2521258_-	hypothetical protein	NA	NA	NA	NA
AWV04187.1\|2521254_2521800_-	hypothetical protein	NA	NA	NA	NA
AWV03396.1\|2521900_2522980_-	AraC family transcriptional regulator	NA	NA	NA	NA
AWV03397.1\|2523055_2525089_+	NADPH-dependent 2,4-dienoyl-CoA reductase	NA	NA	NA	NA
AWV03398.1\|2525194_2525605_-	DUF2471 domain-containing protein	NA	NA	NA	NA
AWV03399.1\|2525825_2526719_-	LysR family transcriptional regulator	NA	NA	NA	NA
AWV04188.1\|2526805_2527591_+	flavodoxin family protein	NA	NA	NA	NA
AWV03400.1\|2527601_2528024_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
AWV03401.1\|2528020_2530735_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	8.7e-89	31.5
AWV03402.1\|2530870_2531356_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
AWV03403.1\|2531450_2533286_-	OmpA family protein	NA	NA	NA	NA
AWV03404.1\|2533210_2533885_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
AWV03405.1\|2533962_2535315_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
AWV03406.1\|2535888_2536401_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
AWV03407.1\|2536474_2538025_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
AWV03408.1\|2538105_2540574_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	4.4e-07	25.3
AWV03409.1\|2540604_2542395_+	hypothetical protein	NA	NA	NA	NA
AWV04189.1\|2542772_2543291_+	hypothetical protein	NA	NA	NA	NA
AWV03410.1\|2543287_2543500_+	hypothetical protein	NA	NA	NA	NA
AWV04190.1\|2543901_2544399_+	hypothetical protein	NA	NA	NA	NA
AWV03411.1\|2544395_2544620_+	hypothetical protein	NA	NA	NA	NA
AWV03412.1\|2544666_2545971_+	hypothetical protein	NA	NA	NA	NA
AWV03413.1\|2546041_2546332_+	PAAR domain-containing protein	NA	NA	NA	NA
AWV03414.1\|2546437_2550205_+	type VI secretion protein VasK	NA	NA	NA	NA
AWV03415.1\|2550213_2551797_+	type VI secretion system protein TssA	NA	NA	NA	NA
AWV03416.1\|2551806_2553621_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP029824

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP029824_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029824_1

178257-178329

Orphan

Consensus_repeat	Method
GTCGATGAGAGTTGGCGCTTTAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029824_1

>merge|CP029824|1|178257-178329|CRISPRCasFinder
GTCGATGAGAGTTGGCGCTTTAGCGCTTACTCTCATCCCATGCTTCGCGGTCGATGAGAGTTGGCGCTTCAGC

>CP029824|1|1|178257-178329|CRISPRCasFinder
GTCGATGAGAGTTGGCGCTTTAGC	GCTTACTCTCATCCCATGCTTCGCG
GTCGATGAGAGTTGGCGCTTCAGC

Protein	Signature genes	Signature genes Name	Protein_function
CP029824.1\|AWU98261.1\|177238_178246_-\|allantoicase	unknown	unknown	gnl\|CDD\|237319
CP029824.1\|AWU98270.1\|188066_188483_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319910
CP029824.1\|AWU98260.1\|176097_176526_+\|ferric-iron-uptake-transcriptional-regulator	unknown	unknown	gnl\|CDD\|236527
CP029824.1\|AWV01150.1\|176699_177224_-\|ureidoglycolate-lyase	unknown	unknown	gnl\|CDD\|237375
CP029824.1\|AWU98253.1\|168507_169602_-\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|235511
CP029824.1\|AWU98259.1\|175136_175955_-\|outer-membrane-protein-assembly-factor-BamE	unknown	unknown	gnl\|CDD\|367908
CP029824.1\|AWU98266.1\|182789_183677_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176106
CP029824.1\|AWU98255.1\|170210_172805_-\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
CP029824.1\|AWU98258.1\|174273_175071_-\|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl\|CDD\|234595
CP029824.1\|AWU98267.1\|183770_184781_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|223135
CP029824.1\|AWV01151.1\|188500_189268_+\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|236959
CP029824.1\|AWU98257.1\|173584_174253_-\|MotA/TolQ/ExbB-proton-channel-family-protein	unknown	unknown	gnl\|CDD\|131843
CP029824.1\|AWU98256.1\|173098_173560_-\|biopolymer-transporter-ExbD	unknown	unknown	gnl\|CDD\|223917
CP029824.1\|AWU98264.1\|180801_181860_-\|L-idonate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|176194
CP029824.1\|AWU98265.1\|181871_182645_-\|gluconate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|236040
CP029824.1\|AWU98268.1\|184868_186941_-\|transketolase	unknown	unknown	gnl\|CDD\|183723
CP029824.1\|AWU98254.1\|169620_170172_-\|lipopolysaccharide-assembly-family-protein	unknown	unknown	gnl\|CDD\|225527
CP029824.1\|AWU98262.1\|178452_179775_-\|C4-dicarboxylate-transporter-DctA	unknown	unknown	gnl\|CDD\|183850
CP029824.1\|AWU98263.1\|179989_180712_+\|FadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225097
CP029824.1\|AWU98269.1\|187157_188015_+\|polyamine-aminopropyltransferase	unknown	unknown	gnl\|CDD\|234843

Protein	Function_ID	Function_description	E-value
CP029824.1\|AWU98261.1\|177238_178246_-\|allantoicase	gnl\|CDD\|237319	PRK13257, PRK13257, allantoicase; Provisional.	0
CP029824.1\|AWU98270.1\|188066_188483_+\|VOC-family-protein	gnl\|CDD\|319910	cd07246, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	7.40781e-32
CP029824.1\|AWU98260.1\|176097_176526_+\|ferric-iron-uptake-transcriptional-regulator	gnl\|CDD\|236527	PRK09462, fur, ferric uptake regulator; Provisional.	1.42191e-61
CP029824.1\|AWV01150.1\|176699_177224_-\|ureidoglycolate-lyase	gnl\|CDD\|237375	PRK13395, PRK13395, ureidoglycolate lyase.	2.04583e-100
CP029824.1\|AWU98253.1\|168507_169602_-\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|235511	PRK05574, holA, DNA polymerase III subunit delta; Reviewed.	1.38006e-146
CP029824.1\|AWU98259.1\|175136_175955_-\|outer-membrane-protein-assembly-factor-BamE	gnl\|CDD\|367908	pfam04355, SmpA_OmlA, SmpA / OmlA family. Lipoprotein Bacterial outer membrane lipoprotein, possibly involved in in maintaining the structural integrity of the cell envelope. Lipid attachment site is a conserved N terminal cysteine residue. Sometimes found adjacent to the OmpA domain (pfam00691).	4.78448e-32
CP029824.1\|AWU98266.1\|182789_183677_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176106	cd08414, PBP2_LTTR_aromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LTTRs involved in degradation of aromatic compounds, such as CbnR, BenM, CatM, ClcR and TfdR, as well as that of other transcriptional regulators clustered together in phylogenetic trees, including XapR, HcaR, MprR, IlvR, BudR, AlsR, LysR, and OccR. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	3.74832e-60
CP029824.1\|AWU98255.1\|170210_172805_-\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
CP029824.1\|AWU98258.1\|174273_175071_-\|4-hydroxy-tetrahydrodipicolinate-reductase	gnl\|CDD\|234595	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional.	3.5302e-141
CP029824.1\|AWU98267.1\|183770_184781_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	0
CP029824.1\|AWV01151.1\|188500_189268_+\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|236959	PRK11713, PRK11713, 16S ribosomal RNA methyltransferase RsmE; Provisional.	6.50787e-97
CP029824.1\|AWU98257.1\|173584_174253_-\|MotA/TolQ/ExbB-proton-channel-family-protein	gnl\|CDD\|131843	TIGR02796, Protein_TolQ, TolQ protein. TolQ is one of the essential components of the Tol-Pal system. Together with TolR, it harnesses protonmotive force to energize TolA, which spans the periplasm to reach the complex of TolB and Pal at the outer member. The tol-pal system proves to be important for maintaining outer membrane integrity. Gene pairs similar to the TolQ and TolR gene pair often number several per genome, but this model describes specificially TolQ per se, as found in tol-pal operons. A close homolog, excluded from this model, is ExbB of the ExbB/ExbD/TonB protein complex, which powers transport of siderophores and vitamin B12 across the bacterial outer membrane. The Tol-Pal system is exploited by colicin and filamentous phage DNA to enter the cell. It is also implicated in pathogenesis in several bacterial species [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	1.42841e-41
CP029824.1\|AWU98256.1\|173098_173560_-\|biopolymer-transporter-ExbD	gnl\|CDD\|223917	COG0848, ExbD, Biopolymer transport protein [Intracellular trafficking and secretion].	6.47711e-44
CP029824.1\|AWU98264.1\|180801_181860_-\|L-idonate-5-dehydrogenase	gnl\|CDD\|176194	cd08232, idonate-5-DH, L-idonate 5-dehydrogenase. L-idonate 5-dehydrogenase (L-ido 5-DH ) catalyzes the conversion of L-lodonate to 5-ketogluconate in the metabolism of L-Idonate to 6-P-gluconate. In E. coli, this GntII pathway is a subsidiary pathway to the canonical GntI system, which also phosphorylates and transports gluconate. L-ido 5-DH is found in an operon with a regulator indR, transporter idnT, 5-keto-D-gluconate 5-reductase, and Gnt kinase. L-ido 5-DH is a zinc-dependent alcohol dehydrogenase-like protein. The alcohol dehydrogenase ADH-like family of proteins is a diverse group of proteins related to the first identified member, class I mammalian ADH. This group is also called the medium chain dehydrogenases/reductase family (MDR) which displays a broad range of activities and are distinguished from the smaller short chain dehydrogenases(~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal GroES-like catalytic domain. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
CP029824.1\|AWU98265.1\|181871_182645_-\|gluconate-5-dehydrogenase	gnl\|CDD\|236040	PRK07523, PRK07523, gluconate 5-dehydrogenase; Provisional.	2.0139e-131
CP029824.1\|AWU98268.1\|184868_186941_-\|transketolase	gnl\|CDD\|183723	PRK12753, PRK12753, transketolase; Reviewed.	0
CP029824.1\|AWU98254.1\|169620_170172_-\|lipopolysaccharide-assembly-family-protein	gnl\|CDD\|225527	COG2980, RlpB, Rare lipoprotein B [Cell envelope biogenesis, outer membrane].	4.01347e-21
CP029824.1\|AWU98262.1\|178452_179775_-\|C4-dicarboxylate-transporter-DctA	gnl\|CDD\|183850	PRK13027, PRK13027, C4-dicarboxylate transporter DctA; Reviewed.	0
CP029824.1\|AWU98263.1\|179989_180712_+\|FadR-family-transcriptional-regulator	gnl\|CDD\|225097	COG2186, FadR, Transcriptional regulators [Transcription].	2.90539e-42
CP029824.1\|AWU98269.1\|187157_188015_+\|polyamine-aminopropyltransferase	gnl\|CDD\|234843	PRK00811, PRK00811, polyamine aminopropyltransferase.	1.40893e-134

>CP029824.1|AWU98261.1|177238_178246_-|allantoicase
MAAPILDPNAPAFTRRYMNLADPRLGAQALFASDEFFAPKERMLNPEPAVFIPGKYDDHGKWMDGWETRRKRTTGHDFCVVRLARPGVIFGVDLDTSHFTGNFPPAASIEACVADGDTPPDDAEWRTIVPATTLQGNSHHYVSVDDAQPVTHLRVNLYPDGGLARLRVYGQPQRDWRHVPAGELVDLAAIENGGYLVAANNQHFGPASQMLMPGRGANMGDGWETRRRREPGNDWAIVALARPGIIRRIEVDTAFFKGNFPDRCSLQAARVAGGTDDSLVTQAMFWAELLGEQKLSMDHVHTFDQLAALGPVTHVRFNIFPDGGVSRLRLWGEPA
>CP029824.1|AWV01150.1|176699_177224_-|ureidoglycolate-lyase
MSGPHILRVERLTREAFAPFGDVIALEGARHFPINGGTTERFHDLATIDVCADGGRPLVSVFRAQPRALPVAVTLMERHPHGSQAFIPLAAVSRYAVVVAPAGEFRPEAMRAFLAVGWQGVNYAKGVWHHPLLALDAVSDFVIVDRGGPQPNCDEIPLDRAWALEFEPACASTA
>CP029824.1|AWU98260.1|176097_176526_+|ferric-iron-uptake-transcriptional-regulator
MTNPTDLKNIGLKATLPRLKILEIFQQSPVRHLTAEDVYRNLLNEQLDIGLATVYRVLTQFEQAGLLTRSNFESGKAVFELNEGSHHDHLVCLDCGRVEEFFDAEIEGRQQAIAKERGFRLQEHSLAMYGSCTTENCPHRKH
>CP029824.1|AWU98259.1|175136_175955_-|outer-membrane-protein-assembly-factor-BamE
MRSAIIAAAAVAALAGCSSYDSVTQRIAQSITPYRITVVQGNFVSQEKAAQLQVGMTREQVRALLGTPLLADMFHADRWDYLFYFKRGSTAIVQQRDLVVTFSGDRLAGWTGAENLPSELDLLADIDGDRGGKKAKAAAAAKAASEAAAARAAQAASAPAAEAVASPSAVPASGAVVDQDANAQAARAANRATNQVSGQGSNARRFTPSTQASGGAPVPGGQPPGAVPAIQPQFQFHRPPQPNASSEASPPVGPQGSDTLQNQPLTAPAQSQ
>CP029824.1|AWU98258.1|174273_175071_-|4-hydroxy-tetrahydrodipicolinate-reductase
MKIAIAGASGRMGRMLIEAVLNDPDAQLVGALDRADSPFLGQDAGAFLGKETGIKLTDDLDAVFAQADYLIDFTRPEGTIAHVEAALRHDVKLVIGTTGFTAEQKAELQAAAAKIGIVFAANMSVGVNVTLKLLEFAAKHFSHGYDIEIIEAHHRHKVDAPSGTALMMGEAVAGALGRSLDDCAVYGRHGVTGERDPSSIGFAAVRGGDIVGDHTVLFAGIGERIEITHKSSSRVSYAQGALRAVRFLSARGAGLFDMQDVLGLR
>CP029824.1|AWU98257.1|173584_174253_-|MotA/TolQ/ExbB-proton-channel-family-protein
MAIPTGVVHYLESGDAITHAVAYVLLAMSVASWCFLFMKTWLLVRAKRQGPRALAAFWRAPSLDAGIAALAGADRERVFAPLAEAARDAVDDHDPATLAARVERSERVLRALRHAMLRSQRRLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAASGQAQIENVAGPVGEALIMTAFGLVVAIPAVLAYNILGRLVRQLAEELDGFARDLHVFVCAQGA
>CP029824.1|AWU98256.1|173098_173560_-|biopolymer-transporter-ExbD
MAFGGLEHHKTSAPMAEINMTPLIDVMLVLLVIFIITAPLMTHAIRLDLPKVAASVARDTPQSVTLSIDDAGKLYWDDAPVALDALPARFRAAAAGGAPPELRLRASRATRYDVIAQVMGAAQAAGLTRIGFVTDVPPQAGGSAVPSAVPANR
>CP029824.1|AWU98255.1|170210_172805_-|leucine--tRNA-ligase
MHERYVPADVEAAAQGDWRAADAYKTKEDSQKPKFYCVSMLPYPSGKLHMGHVRNYTINDVMYRYLRMNGYNTLMPMGWDAFGMPAENAAMANGVPPAKWTYDNIDYMKGQMQSMGLAIDWSREIATCKPDYYKWNQWLFLKMLEKGIAYKKTGTVNWDPVDQTVLANEQVIDGRGWRSGALVEKREIPMYYLRITQYADELLNDLDGLGWPERVKIMQQNWIGKSFGVNFGFPYELDGEKKLLRVFTTRADTIMGVTFCAVAAEHPLATRLAQDKPELLAFIDECKRGGVAEADVATMEKKGVATGFSVTHPLTGEPVEVWIGNYVLMSYGEGAVMGVPAHDERDFAFAKKYDLPIKQVIAAEGQTYSLDAWQEWYGDKEVAVCVNSGKYDGLAYGAAVDAIAADLKAGGFGDKQVTWRLRDWGVSRQRYWGTPIPIIHCPSCGDVPVPEKDLPVVLPEDLVPDGSGNPLAKSEAFLNCTCPKCGAAAKRETDTMDTFVDSSWYFSRYTAPDAETMVDARTDYWMPMDQYIGGIEHAILHLLYSRFWTKVMRDLGLVKFGEPAKNLLTQGMVLNETFYREDASGKKTWYNPADVTVTHDDKGRPVGATLDADGQPVVLGGIEKMSKSKNNGVDPQVLIDLYGADTARLFTMFAAPPEQQLEWSGAGVEGASRFLRRVWSFGYANREALAARGGFDAAALGEADKALRREIYSVLKQADFDYQRLQYNTVVSAAMKMLNAVDGAKGATPGVLRETYGVLLRVLYPVVPHVTFELWKALGYAGEFGPLLDAPWPKVDEAALEQAEIELVLQVNGKVRGALKVAKDASREAIEAAAVADDAFAKFSDGKPAKKIVVVPGRLVNIVV
>CP029824.1|AWU98254.1|169620_170172_-|lipopolysaccharide-assembly-family-protein
MIRRSFLMLVGSAVALSACGFQLRGQQDYAFKHLLVAGAPAPVEARLTRLVEAGSDTKIVKSADDADAVLRMWESRGQNTLTLNKYGSAQEYALFYTLNYTLTSKDGTVLIPPSVIALNRAMTYSDQYTNAKAQEADILFGDMQNDAVDQLMRRLAIVHSLTPAPEDVVPGVAPRAPLPPPPL
>CP029824.1|AWU98253.1|168507_169602_-|DNA-polymerase-III-subunit-delta
MQLRLDALEPHLAKGLAGLYTVYGDEPLLAQEACDRIRAAARAAGFTERSVHTVERGFDWSVLLGATQAMSLFGERQLIELRIPSGKPGKEGADALKTLAATANPDALMLVTLPRLDAATQKSAWFTALQNGGVALKIDPVDRAQLPNWIGQRLSMQGQRVAAGDDGRRALQFIAERVEGNLLAAHQEIQKLGLLYPQGALSFEQVHDAVLNVARYDVFKLNEAMLAGDAARLARMIDGLKGEGEAIVLVMWAVVEELRTLLRIKRGATAGKPLATLLRENRVWGPRERLIGPALNRVSEPVLEKALAFAAQLDRQVKGLTAVVPGRRTQDQPPPDPWDGLFQLAMTVAGARGERPPTAGRVRR
>CP029824.1|AWU98262.1|178452_179775_-|C4-dicarboxylate-transporter-DctA
MSKFLNSLFGRVVVALILGVALGAFFPHFAESLRPLGDGFLKLIKMVIGPIVFCVVVSGMANAGDLKKVGRVGLKAVIYFEIMTTLALGIGLVLAWVTRPGVGMNIDLHSLDASSLASYAKNAESLKDTAGYLMKIIPDTAIDAFAKGDILQILVFAVLFGSALSLLGDNAQRVNSLIEELSHVFFRIIGFIIKLAPLGVLGAIAFTTGKYGVASLKQLGYLVAVFYLSCFVFVTVVLGIVMRLAGFSVFKLIRYLREELSIVLGTASSDAVLPQVMRKLEYMGVKDSTVGLVIPTGYSFNLDGFSIYLTLAVLFIAQATNTPLSTHDLIVVLLVSLVTSKGAHGIPGSAIVILAATLSAIPAIPVLGLVLILPVDWFVGIARALTNLIGNCVATVVVAVWENDIDKVRAKRVLNRELRYVPAEEEGRAAPVAGDQAHAL
>CP029824.1|AWU98263.1|179989_180712_+|FadR-family-transcriptional-regulator
MPVRPAIAHIMKNVPHTVTDAAIATIRDRIEAGVYPVGSLLPAQRQLSEELEISRASLREALSTLEALGMLRIRAGKGVYVESAQATAAQAWQFAEQSSPPDTYQMRYALEGFAARMAARVVSDDDIAWFEDNLADLRVALTESALDEASQLDFDFHMRIIHLAGNAAIESILRSSADIMKESQRMPFYRRELLLSTWHEHRAIVDALIARDAAAAGSAIETHIANAAQRAGIFFPTPGA
>CP029824.1|AWU98264.1|180801_181860_-|L-idonate-5-dehydrogenase
MRMRCMCVVIHGPNDLRVEEQDAGEIGPGQVRVDVAMGGICGSDLHYFRHGGFGAIRLQQPMVLGHEVAGTVAAVAPDVTSVKVGDRVAVNPSRPCGACRYCLEGLPNQCLDMRFYGSAMRMPHVQGAFRNALVCDAAQCVKVADHVPLSLAALAEPFAVGLHAVSRAGPLIGKRVLVSGCGPIGVLAVAAARVHGAAEIVATDVVEAPLEVARALGADRTINAAADAGWVARYGADKGTFDVMIECSGNARALRDGLDVMRPRGVVVQLGLGGDVSLPQNVVVAKELSICGSFRFHAEFALAVQLINAARVDLRPAITRVFPMRDANLAFELAGDRQRAMKVLIDFAGEAA
>CP029824.1|AWU98265.1|181871_182645_-|gluconate-5-dehydrogenase
MTNALERFRLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARHLRDEGFAADHAVFDVAEHAQVRAAIDDFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGVFNVAQAVARHMIARGRGKIINICSVQSELARPTIAPYAASKGAVRMLTKGMCADWARHGIQANGLAPGYFETELNRALVDDAAFSDWLCKRTPAGRWGRVDELCGAAIFLASAASDFVNGQTLFVDGGLTSAV
>CP029824.1|AWU98266.1|182789_183677_+|LysR-family-transcriptional-regulator
MELKQLRAFVTLAEELHFGRAAQRLFIVQPALSMQIKALEEELGARLFERDRHKVELSDTGRVFLPEARATLQQAARAEQMARLSSRGEIGTLRIAFVSSVLPALLPAVLRTMRERYPLIALELKDMPTPDQIAALRDRRIDFGMIRLPAAYAGIDTRVVLEEGFVVALPLDHPLAAHDTIPPTALRGQPAFVLARRYAPGFHDDMLLALSRAGTTLEFAQEFGEFTTMLALVAAGMGIGLIPAEAASALPPNVLARPLDLAGYRTGIGLAWTDLDSPLKRAFVDALEQVTADRR
>CP029824.1|AWU98267.1|183770_184781_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MTIRVAINGYGRIGRNTLRAFYENGKKHDLEIVAINDLGDAKTNAHLTQYDTAHGKFPGEVSVDGDYLVVNGDKIRVLANRNPAELPWGELGVDVVMECTGFFTTKEKASAHLKGGAKKVIISAPGGKDVDATIVYGVNHNVLKAEHTVISNASCTTNCLAPLVKPLNDKIGLETGLMTTIHAYTNDQVLTDVYHEDLRRARSATHSQIPTKTGAASAVGLVLPELNGKLDGYAIRVPTINVSIVDLSFIAKRDTTVEEVNAIMKEASEGALKGILGYNDAPLVSIDFNHNPASSTFDATLTKVSGRLVKVSSWYDNEWGFSNRMLDTAVAFANAK
>CP029824.1|AWU98268.1|184868_186941_-|transketolase
MPPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRDGAKIVDHHTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHDVDAVDAAIAKAKLSDKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKWEPFVIPQEVYAAWDAKEAGKRAEADWGATFAQYRAKFPAEAAEFERRMANQLPADWAQKAAAIIAGANERAETVATRKASQQAIEGLAAALPELLGGSADLTGSNLTNWKASKAVRANPEGAGVVLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPSIFVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNHDVWRPADTVETAVAWTHAVAADRPSSLIFSRQNLAFNPRTDAQIANIEKGGYVLKDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAGVTAFWHKYVGLEGGVVGIDTFGESAPAGVLFKYFGFTVDKVVETAKAVLA
>CP029824.1|AWU98269.1|187157_188015_+|polyamine-aminopropyltransferase
MSTTLLFHPTPDATYGFPNARRLARVASLHQQIEVWETPQLGRLFTLDGRPMTSVGDEYVYHECMTHPAALAHPSPRKALVLGGGDGGAARQLLKHACIERIVIAELDDEVVGMARRYLDDVHQGALDDPRVEVVIGDAAHFVESTIEHFDLVVFDLTPPDSPAAGLYTRAFYARLKRILTPCGAISMHLGSPVFHAARIAALLDDLRASFAVVDPLSAHVPLYGSQWLMAIASDTLDAAALFAHDVDERLAARHVQGLRYYDARLHASLFALPHALRDTLGARR
>CP029824.1|AWU98270.1|188066_188483_+|VOC-family-protein
MTDPRPANVPWLTPYLAVRNARAAIDFFKAAFGFELRDVHDEDGAIMHVEMAYHGRLIVMFAPEGAFGSIALTPKSAHATAPQSFYLYVDDVDATWQRALDAGAKSLSAPQDQFWGDRFAQIEDLDGYRWALARHLDA
>CP029824.1|AWV01151.1|188500_189268_+|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MNEATTTAAVPRFFVDAALHTDATLALPADVARHAQVLRLQPGDVLALFDGTGGQYRARLVEIDKRSALAQIDAFEPAEAEPPYRVTLAQGIAGGDKMDWVIEKAVELGVAAIVPLSTARGVVKLSGERADKRVAHWRGVVRASCEQCGRNRLPEVAPVLGFNAWLDALPAEPAGGELRLLLSPRASIPFASLPDTPPGAPVTLLIGPEGGLSPDEENAARARGFTALSLGPRVLRTETAGAAVLAALAARWGGW

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Crispr_ID: CP029824_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029824_2

744912-745037

Orphan

Consensus_repeat	Method
GGTCCCATGGCGTGGCTGGGTGGAGTCAGCGCTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029824_2

>merge|CP029824|2|744912-745037|CRISPRCasFinder
GGTCCCATGGCGTGGCTGGGTGGAGTCAGCGCTTTAGCGCTTACTCCATCCCCACGGCGGTCGACCCGAGTTAGTGCTTTAGCACTTACTCAGGTCCCATGGCGTGGCTGGATGGAGTCAGCGCTT

>CP029824|2|2|744912-745037|CRISPRCasFinder
GGTCCCATGGCGTGGCTGGGTGGAGTCAGCGCTT	TAGCGCTTACTCCATCCCCACGGCGGTCGACCCGAGTTAGTGCTTTAGCACTTACTCA
GGTCCCATGGCGTGGCTGGATGGAGTCAGCGCTT

Protein	Signature genes	Signature genes Name	Protein_function
CP029824.1\|AWU98738.1\|751811_752342_-\|SET-domain-containing-protein-lysine-N-methyltransferase	unknown	unknown	gnl\|CDD\|380916
CP029824.1\|AWU98722.1\|734383_735439_-\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|119324
CP029824.1\|AWU98729.1\|741953_742733_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213186
CP029824.1\|AWU98735.1\|749034_749265_-\|DUF3717-domain-containing-protein	unknown	unknown	gnl\|CDD\|378869
CP029824.1\|AWU98728.1\|741201_741957_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223487
CP029824.1\|AWU98731.1\|745274_746174_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
CP029824.1\|AWU98732.1\|746367_746901_+\|adenylate-cyclase	unknown	unknown	gnl\|CDD\|143628
CP029824.1\|AWU98721.1\|732594_734379_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|223488
CP029824.1\|AWU98725.1\|737918_738896_-\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|119323
CP029824.1\|AWU98737.1\|750195_751680_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
CP029824.1\|AWU98723.1\|735639_736797_-\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380556
CP029824.1\|AWU98734.1\|747573_748500_+\|phenylalanine-4-monooxygenase	unknown	unknown	gnl\|CDD\|237020
CP029824.1\|AWU98736.1\|749387_750080_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|223816
CP029824.1\|AWU98730.1\|743180_744866_-\|choline-dehydrogenase	unknown	unknown	gnl\|CDD\|235000
CP029824.1\|AWV01184.1\|748633_748942_+\|4a-hydroxytetrahydrobiopterin-dehydratase	unknown	unknown	gnl\|CDD\|234845
CP029824.1\|AWU98726.1\|738892_739777_-\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223633
CP029824.1\|AWU98727.1\|739924_741124_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|380550
CP029824.1\|AWU98724.1\|737003_737426_+\|hypothetical-protein	unknown	unknown	unknown
CP029824.1\|AWU98739.1\|752521_753634_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|239242
CP029824.1\|AWU98733.1\|746981_747482_-\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439

Protein	Function_ID	Function_description	E-value
CP029824.1\|AWU98733.1\|746981_747482_-\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	3.67352e-42
CP029824.1\|AWU98738.1\|751811_752342_-\|SET-domain-containing-protein-lysine-N-methyltransferase	gnl\|CDD\|380916	cd10518, SET_SETD1-like, SET domain (including post-SET domain) found in SET domain-containing proteins (SETD1A/SETD1B), histone-lysine N-methyltransferases (KMT2A/KMT2B/KMT2C/KMT2D) and similar proteins. This family includes SET domain-containing protein 1A (SETD1A), 1B (SETD1B), as well as histone-lysine N-methyltransferase 2A (KMT2A), 2B (KMT2B), 2C (KMT2C), 2D (KMT2D). These proteins are histone-lysine N-methyltransferases (EC 2.1.1.43) that specifically methylate 'Lys-4' of histone H3 (H3K4me).	4.98527e-34
CP029824.1\|AWU98729.1\|741953_742733_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213186	cd03219, ABC_Mj1267_LivG_branched, ATP-binding cassette component of branched chain amino acids transport system. The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).	5.93755e-111
CP029824.1\|AWU98732.1\|746367_746901_+\|adenylate-cyclase	gnl\|CDD\|143628	cd07890, CYTH-like_AC_IV-like, Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily. This subgroup contains class IV ACs and similar proteins. AC catalyzes the conversion of ATP to 3',5'-cyclic AMP (cAMP) and PPi. cAMP is a key signaling molecule which conveys a variety of signals in different cell types. In prokaryotes, cAMP is a catabolite derepression signal which triggers the expression of metabolic pathways including the lactose operon. Six non-homologous classes of ACs have been identified (I-VI). Class IV ACs are found in this group. In bacteria, the gene encoding Class IV AC has been designated cyaB and the protein as AC2. AC-IV occurs in addition to AC-I in bacterial pathogens such as Yersinia pestis (plague disease). The role of AC-IV is unknown but it has been speculated that it may be a factor in pathogenesis, perhaps providing cAMP for a secondary internal signaling function, or for secretion and uptake into host cells, where it may disrupt normal cellular processes. This subgroup belongs to the CYTH/triphosphate tunnel metalloenzyme (TTM)-like superfamily, whose enzymes have a unique active site located within an eight-stranded beta barrel.	1.41733e-43
CP029824.1\|AWU98735.1\|749034_749265_-\|DUF3717-domain-containing-protein	gnl\|CDD\|378869	pfam12512, DUF3717, Protein of unknown function (DUF3717). This family of proteins is found in bacteria. Proteins in this family are typically between 75 and 117 amino acids in length. There is a conserved AIN sequence motif. There are two completely conserved residues (L and Y) that may be functionally important.	7.07242e-29
CP029824.1\|AWU98728.1\|741201_741957_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223487	COG0410, LivF, ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism].	4.7424e-106
CP029824.1\|AWU98731.1\|745274_746174_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.8813e-37
CP029824.1\|AWU98737.1\|750195_751680_+\|sensor-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.03754e-49
CP029824.1\|AWU98721.1\|732594_734379_-\|metal-dependent-hydrolase	gnl\|CDD\|223488	COG0411, LivG, ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism].	3.15612e-114
CP029824.1\|AWU98725.1\|737918_738896_-\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|119323	cd06581, TM_PBP1_LivM_like, Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	2.45454e-67
CP029824.1\|AWU98723.1\|735639_736797_-\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380556	cd06333, PBP1_ABC_RPA1789-like, type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, RPA1791-1793), involved in active transport of lignin-derived aromatic substrates, and its close homologs. This group includes RPA1789 (CouP) from Rhodopseudomonas palustris and its close homologs in other bacteria. RPA1789 (CouP) is the periplasmic binding-protein component of an ABC system (CouPSTU; RPA1789, RPA1791-1793) that is involved in the active transport of lignin-derived aromatic substrates. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).	6.52362e-154
CP029824.1\|AWU98734.1\|747573_748500_+\|phenylalanine-4-monooxygenase	gnl\|CDD\|237020	PRK11913, phhA, phenylalanine 4-monooxygenase; Reviewed.	2.55191e-161
CP029824.1\|AWU98736.1\|749387_750080_+\|DNA-binding-response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.18094e-72
CP029824.1\|AWU98730.1\|743180_744866_-\|choline-dehydrogenase	gnl\|CDD\|235000	PRK02106, PRK02106, choline dehydrogenase; Validated.	0
CP029824.1\|AWV01184.1\|748633_748942_+\|4a-hydroxytetrahydrobiopterin-dehydratase	gnl\|CDD\|234845	PRK00823, phhB, pterin-4-alpha-carbinolamine dehydratase; Validated.	3.28465e-49
CP029824.1\|AWU98727.1\|739924_741124_-\|ABC-transporter-permease	gnl\|CDD\|380550	cd06327, PBP1_SBP-like, periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs). Periplasmic substrate-binding domain of active transport proteins found in gram-negative, gram-positive bacteria, and archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.	0
CP029824.1\|AWU98726.1\|738892_739777_-\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|223633	COG0559, LivH, Branched-chain amino acid ABC-type transport system, permease components [Amino acid transport and metabolism].	2.38818e-72
CP029824.1\|AWU98739.1\|752521_753634_-\|oxidoreductase	gnl\|CDD\|239242	cd02932, OYE_YqiM_FMN, Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis. Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing agent. The YqjM enzyme exists as a homotetramer that is assembled as a dimer of catalytically dependent dimers, while other OYE members exist only as monomers or dimers. Moreover, the protein displays a shared active site architecture where an arginine finger at the COOH terminus of one monomer extends into the active site of the adjacent monomer and is directly involved in substrate recognition. Another remarkable difference in the binding of the ligand in YqjM is represented by the contribution of the NH2-terminal tyrosine instead of a COOH-terminal tyrosine in OYE and its homologs.	0
CP029824.1\|AWU98722.1\|734383_735439_-\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|119324	cd06582, TM_PBP1_LivH_like, Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivH forms a heterodimer with another TM, LivM, to generate the transmembrane pore. LivM is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	1.17625e-42

>CP029824.1|AWU98730.1|743180_744866_-|choline-dehydrogenase
MTTQRTLEGEFDYVIVGAGTAGCVLANRLTEDPDIHVLLLEAGGKDDYHWIHIPVGYLYCIGNPRTDWLYKTQPEAALNGRALSYPRGRVLGGCSSINGMIYMRGQREDYDSWAHETGDEGWSWDSVLPIFKRSEDHHAGASDAHGAGGYWRVEKQRLRWEILESFAQAAQQTGIPATDDFNRGDNSGVGYFEVNQKRGVRWNTSKAFLRPAMARPNLTVITGAQAQRVIFEGRRAVGVEYHGGGTDYVARARAEVLLTSGAVNSPQLLELSGIGCGRRLQALGIDVVQDLPGVGENLQDHLQLRMAFRVEGVRTLNTLSAHWWGKLMIGAEYALLQRGPMSMAPSQLGAFAKSDPEDPALTRPDLEYHVQPLSLERFGEPLHSFNAFTASVCHLRPTSRGSVHVTSADPGIAPAIAPNYLSTDHDRHVAANALRLTRRIASAPALARYRPEEILPGTRYRTEAELIEAAGAVGTTIFHPVGTCRMGRADDERAVVDSRLRVRGVAGLRIVDASVMPFITSGNTNSPTLMIAERASDMIRADRRAARDATPVRTEATVTAA
>CP029824.1|AWU98729.1|741953_742733_-|ABC-transporter-ATP-binding-protein
MILGDTILETRGLTKEFRGFTAVNGVNLRVRRGAIHALIGPNGAGKTTCFNLLTKFLTPTAGQIVFNGIDITDERPAQVARRGIIRSFQISAVFPHLTALQNVRIGLQRALGTEFHFWRSERTLKRLDDRAMDLLTQVGLTDFAHVPTVELAYGRKRALEIATTLAMEPELMLLDEPTQGMGHEDVDRVTALIKKVASGRTILMVEHNMNVIAGISDTITVLQRGEVLAEGSYAEVSKNPLVIEAYMGSADAALAGAHA
>CP029824.1|AWU98728.1|741201_741957_-|ABC-transporter-ATP-binding-protein
MKHSEREERELSGVESGTPALEITGLEAWYGESHILHGVDLTVHRGEVVTLLGRNGAGRTTTLRAIMGLTGRRSGSIKVAGNETIGLATHRIAHFGIGYCPEERGIFSSLSCEENLMLPPPIGSREHAMSLDEIYAMFPNLASRRQSQGTRLSGGEQQMLAVARILRTGANLLLLDEISEGLAPVIVQALARMIVALKARGYTIVMVEQNFRFAAPLADRFYVMEHGRIVEHFRAAELESKMPTLHDLLGV
>CP029824.1|AWU98727.1|739924_741124_-|ABC-transporter-permease
MKMKTLAHACLALATAALTAGAAHAADTVKIGFITDMSGLYADIDGQGGLEAIRMAVADFGGKVLGKPIEVVYADHQNKADIAASKAREWMDRGGLDLLVGGTNSATALSMNQVAAEKKKVYINIGAGADTLTNEQCTPYTVHYAYDTMALAKGTGSAVVKQGGKSWFFLTADYAFGKALEKNTSDVVKANGGQVLGYVRHPLSASDFSSFLLQAQSSKAQILGLANAGGDTINAIKAAKEFGITKTMKLAALLMFINDVHSLGLETTQGLVLTDSWYWNRDAASRQWAQRYFGKMKKMPSSLQAADYSSVTTYLKAVQAAGTTDSDKVMAELKKAKISDFYAKGYIRADGSMIHDMYLMEVKKPSESKEPWDYYKVLATIPGEQAFTTKQETRCAMWK
>CP029824.1|AWU98726.1|738892_739777_-|branched-chain-amino-acid-ABC-transporter-permease
MEIFGIPLPAMLSQLLLGLVNGSFYAILSLGLAVIFGLLNVINFAHGALFMLGAMLAWMGLSYLGLPYWAMLVLAPLVVGAFGIAIERSMLRWLYKLDHLYGLLLTFGLTLVVEGVFRSIYGASGQPYDVPSQLSGATNLGFMFLPNYRAWVVVASLAVCLATWFVIEKTRLGAYLRAGTENPKLVEAFGVNVPMMITLTYGFGVALAAFAGVLAAPVIQVSPLMGQPMIITVFAVVVIGGMGSILGSIVTGLMLGVIEGFTRVFYPEASATVVFVIMAIVLLFRPAGLFGKEK
>CP029824.1|AWU98725.1|737918_738896_-|branched-chain-amino-acid-ABC-transporter-permease
MMQRKVLYGVLLAALLVAPFIGAYPVFVMKVLTFALFAAAFNLLIGYTGLLSFGHAMFLATAGYATGYSMQTLGFTPELGVLVGTVVATLLGLVVGLFAIRRQGIYFAMITLAFAQMVYFIYLQAPFTHGEDGLQGVPRGHLFGLLDLSNDVALYYVVLAVVVVACAFIVRVVHSPFGQVLVAIKENEARAISLGYDTDRFKLLAFILSAGLAGLAGSLKVLVLGFETLSDAHWTMSGLVVLMTLVGGMGTLFGPLLGAALIVALEDRLGDIGEWLASTTGVAWFHSLGESTTIVTGLIFIACVLAFRRGIVGEMVARIKPLRAS
>CP029824.1|AWU98724.1|737003_737426_+|hypothetical-protein
MRSSSVVRMKKAKKCGSVRVIDARATIAGRCAGQARPGHARRRRKIGKAAVHAETGASATTGEGTMPANRAGTRVPAAGGLGKAGKYRCAPNDERAAPAALPAPIHRPALLIQPYSLFCIVLIGELPTDFPDRSVGESQV
>CP029824.1|AWU98723.1|735639_736797_-|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein
MKMNRWMEAVLAAGLVCAAATASAQVKIGVTLSATGPAASLGIPEKNTIALLPKEIAGKSVQYIVLDDASDTSRAVQNVRKLIDEDHVDAIIGSSVTPNSLAMLDPVSQGKTPTISLAASAQIIAPMDAKRAWMFKVPQNDQLMADAIAGYMAKHGVKTVGFIGFADAYGDSWYKTFSAAAEKNGLKIVSNERFNRTDASVMGQVLKLMGSNPDAMLIAGSGTPAALPAKTLKERGYKGKVYQTHGVANNDFLRVCGKDCEGEILPAGPVLVTEQLPDSNPVKKAALGYKAAYEKAYGAGSLATFGGHAWDAGLLLQRAIPDALKKGQPGSEAFREALRASLESVKDLPVSHGVINMTSTDHNGFDTRARVMVQIVDGKWKLQSE
>CP029824.1|AWU98722.1|734383_735439_-|branched-chain-amino-acid-ABC-transporter-permease
MDLSIAAILAQDGITTGAIYALLSLALVLVFSVTRVIFIPQGEFVAYGALTLAALQAQKFPATCWLLFVMGVACFLLEVGGLIRHRERRHQLGRTLATLGSRYILLPLAVFAITRSFAAQPMPMLAQIALTLAIVVPMGPFVYRLVYQPIAEGTTLLLLIVSVAVHFAMVGLGLVMFGAEGSRTNGFSDASLSIGSMTVSVQSILVVVTALVLIGALYVYFGRTIAGKALRATSVNRLGARLVGIGTTEAGRLAFTFAAGLGVLSGILVGPLTTIYYDSGFLIGLKGFVGAIIGGLVSYPLAAAGSLLVGVLESYSSFWASAYKEVIVFTLIIPVLLWRSFVTPHAEEEEE
>CP029824.1|AWU98721.1|732594_734379_-|metal-dependent-hydrolase
MKTMVRNKTFWMFLVVLFALPVLPGALQVPEYWITLLNYIGLYAIVAIGLVLLTGVGGMTSFGQAAFVGIGAYATAFLTTRYGVSPWLALIVGVVLTALVALVLGAVTMRLSGHFLPLGTIAWGLALFYLFGNLELLGKYDGINGIPALNLFGITLESGRSLYFLIWAVVLAAIVSVQNLLNSRPGRAIRALRGGGVMAEAMGVNTAWMRVVIFVYAAVLAAVSGFLYAHLQRAVNPTPFGLNHGIEFLFMAVVGGVSHVWGAVLGAAILTVLQDYLQTLLPKLLGSEGNFEIIVFGVLMVLLLQYARQGVWPFVARLFPRGPRAHVPEHADSLPQRAKPAAGEPLLVVDNARKQFGGLVAVNDVSFDVKAGQIIGLIGPNGAGKSTTFNLVTGVLKPTGGAITFRGERIDGLTSRQIVRRGIGRTFQHVKLLPAMTVLENVAIGAHLRGHTGVWRSVARLNAHEEAQLLAEAARQIRRVGLEKHMYDEAGSLALGQQRILEIARALCCDPTLLLLDEPAAGLRYQEKQQLADLLRRLKAEGMSVLLVEHDMDFVMNLTDRLVVMEFGTRIAEGLPQDVQQDPAVLEAYLGGVE
>CP029824.1|AWU98731.1|745274_746174_+|LysR-family-transcriptional-regulator
MDLILLRAFATVAREGNLTRAAAQLHLTQPAVSLQIKHLQETLGVTLFTRTSRGLALTRDGQTLLPHAERALAAAADVQRAAAALRHEVRGRLRIGTILDPGFLRLGGFLRALVETHPQIETALRHGMSGWVIEQVRAQALDVGYYIGRPGEDDQLDGALFHTVTLTHFQYRVLAPAGWKERVQRAHDWRALAALPWIWTPPASAHHRLLSRRFAEAGAQPVKVAEVDQEQSMLDLVKSGIGLTLARDSTALAEAHAHALTIVERVTVPTELTFVTLAERRDEPAIAAALRLIEAQWTI
>CP029824.1|AWU98732.1|746367_746901_+|adenylate-cyclase
MARNIEIKARAREFDQLRERAATLAAEAPLFYRQQDFFYDVPRGRLKLRRFEDGTPAELIFYQRDDRDGPKASYYTRSPVTNPDAMHALLATALTTRGIVTKERHVYLAGRTRIHLDRVDGLGDFIELEVVLGPDDDEAGGEAEAHDVFTKLGVSQDDLVAVAYVDLLNAGTPHEAA
>CP029824.1|AWU98733.1|746981_747482_-|Lrp/AsnC-family-transcriptional-regulator
MRRMLMLELDHFDLALLDVLQRFGRATHQQLGEEVPLSPSQIGRRLQRLEAAGVIEGYRVMLRPEKLGLGVTAFTSLKLKHHGDSIIEQFQQQIDVLPEVLECHAVVGDADYLLRIVAPDLNALSQFVMKKLMRVPGVDSVRSNIVLTTFKRNGALPLAHLAPGAA
>CP029824.1|AWU98734.1|747573_748500_+|phenylalanine-4-monooxygenase
MVPNHSVQSLIMSTVVTAKLQEQFDAGLETRADFTIDQPLERYGQVDHAVWKQLYARQSALLRGRACGAFVAGLGKIDLPADRVPSFADVNRQLKPATGWEIVAVPGLVPDRVFFGHLANRRFPVTWWMRRPDQLDYLQEPDCFHDLFGHVPLLIDPVFADYMQAYGRTALAVADDEAALARLARLYWYTVEFGLIRDPHGTNGLSIYGAGIVSSKGESLYSLESAAPNRLGFDLERVMRTKYRIDTFQKTYFVIDDFAQLFALADIDGRALADRLAALPEFAAGAVLDTDRVLHRGTGEGWPDDADA
>CP029824.1|AWV01184.1|748633_748942_+|4a-hydroxytetrahydrobiopterin-dehydratase
MIHKLTSEERKTRLEGLPLWTAVPGRDAIQRSLRFADFNEAFGFMTRVAIKAQEMNHHPEWFNVYNRVDVTLSTHDADGLTERDIELALFIDRAGAHAQPAA
>CP029824.1|AWU98735.1|749034_749265_-|DUF3717-domain-containing-protein
MSDISINDLEAAINFWRARSPSSGDELKLCEEASALSKPYALLIVQRESALQLEGLDPKARKAYETYVRLKDGLES
>CP029824.1|AWU98736.1|749387_750080_+|DNA-binding-response-regulator
MRLLLIEDDRPIARGIQSSLEQAGFTVDMVHDGIFAEQALAQNRHELVILDLGLPGIDGMTLLTRFRQTNRHTPVIVLTARDELNDRIQGLNSGADDYMLKPFEPAELEARIRAVMRRSGPHSDMPRPEVSLGGVRLSGVDRRIFNDDKPLELSPREFAVLEMLLLRHGRVVSKAQLQDHLTHFGGDLGDTAIEVYVHRVRKKLEQCRVEIVTVRGFGYLLQEIRQTASV
>CP029824.1|AWU98737.1|750195_751680_+|sensor-histidine-kinase
MSPDPAVTTSLRRSLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVIDRSLADLATAISKQIQIAGPDAPFTVPPLAQAMFSDPAEALIYRISDGEQELAGDPKLPLRGINVRRMHHAYVFEAEYDNRAVRVAQVRVDNVEGGKPMVVEVAQPVRHRYRIAAEFLVAIMMPLLLLLLAGWGIVWRVVNQQLGPLTHLADSLNRQTHTSLEPVDETEVPLEIRPLTSAMNALLGRLKTALDAQRKFIADAAHQLRTPLTAVKLHAEQAAVARDPHQTFAAVRELRAAADRAVRLSNQLLSLARAEPGEQAARFVDVDLAAMAFETGAEWVPRALASHVDLGFQRSDDPGDDEKLIVRGNPVLLREVIANLLDNALKYVPLARPDGARITVNVARSALEDGQPAAEIVVEDNGPGVPANQQADLFKRFFRGDAQSGNGVETGAGLGLAIVHDIIAMHGGTVSYEDASEGGSRFVVRVPLAQRTEKPASETPAAASAH
>CP029824.1|AWU98738.1|751811_752342_-|SET-domain-containing-protein-lysine-N-methyltransferase
MSSRRIAVRRSGVHGKGVFAVAPIRAGERVVEYKGERISWKEALRRHPHDPSEPNHTFYFALDEGGVIDGKIDGNSARWINHSCAPNCEAEEVKGRVYIHALRDIGPEEELFYDYGLVIDAKLTKKLKREYACHCGAASCRGTLLATSEDGEKKKKKKAKKDGKSESSAKDKKNKK
>CP029824.1|AWU98739.1|752521_753634_-|oxidoreductase
MTALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAGLLCIEATAVEPDGRITHGDLGLWDDATEAALKPVLAAIRKHSPVRVAMQLSHAGRKASSDVPWQGGQLVSVADGGWLPHGPSAVPHKEGETPPLALDAAGLNRIRDAFAAAAKRAARLGIDAIEVHAAHGYLLHQFLSPLANRRTDEYGGSRENRMRFPLEIFEIVRAAFPEDRPVGVRVSATDWVEGGWELDDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRAVGMPTMAVGLINEPAHANRLIEAGDADFVAMARAMLYDPRWPWHAAAELGAQVTAPPQYWRSQPREHKALFGDIAFGQR

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Crispr_ID: CP029824_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029824_3

1065468-1065587

Orphan

Consensus_repeat	Method
CACTCGAAGCGCTGTGGTTTTCAACGGTGAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029824_3

>merge|CP029824|3|1065468-1065587|CRISPRCasFinder
CACTCGAAGGGCGGTGCATTCTAACGGTGAGAGCGGACGTGTGGTCCGCAACGAGCAGATTTCAATGCGCGTACCAACCTTCTCAAGCGACTCGAAGCGCTGTGCAATTCAATGGTGAGC

>CP029824|3|3|1065468-1065587|CRISPRCasFinder
CACTCGAAGGGCGGTGCATTCTAACGGTGAG	AGCGGACGTGTGGTCCGCAACGAGCAGATTTCAATGCGCGTACCAACCTTCTCAAGC
GACTCGAAGCGCTGTGCAATTCAATGGTGAGC

Protein	Signature genes	Signature genes Name	Protein_function
CP029824.1\|AWU99001.1\|1058573_1059641_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237907
CP029824.1\|AWU98998.1\|1055477_1056398_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990
CP029824.1\|AWU99004.1\|1062378_1063341_+\|Inward-rectifier-potassium-channel	unknown	unknown	gnl\|CDD\|375232
CP029824.1\|AWU98997.1\|1055032_1055317_-\|hypothetical-protein	unknown	unknown	unknown
CP029824.1\|AWU99005.1\|1063378_1063993_-\|glutathione-S-transferase	unknown	unknown	gnl\|CDD\|239344
CP029824.1\|AWU99015.1\|1077297_1078488_-\|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl\|CDD\|235655
CP029824.1\|AWU99014.1\|1076581_1077301_-\|dethiobiotin-synthase	unknown	unknown	gnl\|CDD\|234625
CP029824.1\|AWU99010.1\|1073782_1074169_+\|hypothetical-protein	unknown	unknown	unknown
CP029824.1\|AWU99003.1\|1061168_1062188_+\|sulfate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224529
CP029824.1\|AWU98999.1\|1056509_1057148_+\|glutathione-S-transferase	unknown	unknown	gnl\|CDD\|182533
CP029824.1\|AWU99011.1\|1074165_1074570_+\|hypothetical-protein	unknown	unknown	unknown
CP029824.1\|AWU99002.1\|1059822_1060716_-\|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl\|CDD\|188637
CP029824.1\|AWU99006.1\|1064407_1064965_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
CP029824.1\|AWU99008.1\|1070357_1072025_-\|Na+/H+-antiporter	unknown	unknown	gnl\|CDD\|129911
CP029824.1\|AWU99000.1\|1057204_1058476_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341028
CP029824.1\|AWU99012.1\|1074653_1075379_+\|copper-homeostasis-protein-CutC	unknown	unknown	gnl\|CDD\|225684
CP029824.1\|AWU99007.1\|1066700_1070273_+\|pyruvate-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|237279
CP029824.1\|AWU99016.1\|1078487_1079831_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|235894
CP029824.1\|AWU99013.1\|1075520_1076540_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|273075
CP029824.1\|AWU99009.1\|1072321_1073608_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923

Protein	Function_ID	Function_description	E-value
CP029824.1\|AWU99001.1\|1058573_1059641_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|237907	PRK15092, PRK15092, DNA-binding transcriptional repressor LrhA; Provisional.	2.46205e-58
CP029824.1\|AWU98998.1\|1055477_1056398_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	1.94781e-76
CP029824.1\|AWU99004.1\|1062378_1063341_+\|Inward-rectifier-potassium-channel	gnl\|CDD\|375232	pfam17655, IRK_C, Inward rectifier potassium channel C-terminal domain. This cytoplasmic C-terminal domain has an Ig fold.	1.15568e-30
CP029824.1\|AWU99009.1\|1072321_1073608_+\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.3686e-60
CP029824.1\|AWU99005.1\|1063378_1063993_-\|glutathione-S-transferase	gnl\|CDD\|239344	cd03046, GST_N_GTT1_like, GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress. GSTs also show GSH peroxidase activity and are involved in the synthesis of prostaglandins and leukotrienes. The GST fold contains an N-terminal TRX-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GTT1, a homodimer, exhibits GST activity with standard substrates and associates with the endoplasmic reticulum. Its expression is induced after diauxic shift and remains high throughout the stationary phase. S. pombe GST-III is implicated in the detoxification of various metals.	5.31095e-29
CP029824.1\|AWU99015.1\|1077297_1078488_-\|8-amino-7-oxononanoate-synthase	gnl\|CDD\|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	0
CP029824.1\|AWU99014.1\|1076581_1077301_-\|dethiobiotin-synthase	gnl\|CDD\|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	1.23677e-91
CP029824.1\|AWU99016.1\|1078487_1079831_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|235894	PRK06943, PRK06943, adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional.	0
CP029824.1\|AWU99003.1\|1061168_1062188_+\|sulfate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224529	COG1613, Sbp, ABC-type sulfate transport system, periplasmic component [Inorganic ion transport and metabolism].	2.98462e-171
CP029824.1\|AWU98999.1\|1056509_1057148_+\|glutathione-S-transferase	gnl\|CDD\|182533	PRK10542, PRK10542, glutathionine S-transferase; Provisional.	2.11045e-29
CP029824.1\|AWU99002.1\|1059822_1060716_-\|4-hydroxy-tetrahydrodipicolinate-synthase	gnl\|CDD\|188637	cd00950, DHDPS, Dihydrodipicolinate synthase (DHDPS). Dihydrodipicolinate synthase (DHDPS) is a key enzyme in lysine biosynthesis. It catalyzes the aldol condensation of L-aspartate-beta- semialdehyde and pyruvate to dihydropicolinic acid via a Schiff base formation between pyruvate and a lysine residue. The functional enzyme is a homotetramer consisting of a dimer of dimers. DHDPS is member of dihydrodipicolinate synthase family that comprises several pyruvate-dependent class I aldolases that use the same catalytic step to catalyze different reactions in different pathways.	7.26353e-114
CP029824.1\|AWU99006.1\|1064407_1064965_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	2.09017e-62
CP029824.1\|AWU99012.1\|1074653_1075379_+\|copper-homeostasis-protein-CutC	gnl\|CDD\|225684	COG3142, CutC, Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism].	5.78483e-57
CP029824.1\|AWU99008.1\|1070357_1072025_-\|Na+/H+-antiporter	gnl\|CDD\|129911	TIGR00831, Putative_Na+/H+_exchanger_Rv2287/MT2345/Mb2309., Na+/H+ antiporter, bacterial form. The Monovalent Cation:Proton Antiporter-1 (CPA1) Family (TC 2.A.36) The CPA1 family is a large family of proteins derived from Gram-positive and Gram-negative bacteria, blue green bacteria, yeast, plants and animals. Transporters from eukaryotes have been functionally characterized, and all of these catalyze Na+:H+ exchange. Their primary physiological functions may be in (1) cytoplasmic pH regulation, extruding the H+ generated during metabolism, and (2) salt tolerance (in plants), due to Na+ uptake into vacuoles. This model is specific for the bacterial members of this family. [Transport and binding proteins, Cations and iron carrying compounds].	6.81783e-116
CP029824.1\|AWU99007.1\|1066700_1070273_+\|pyruvate-ferredoxin-oxidoreductase	gnl\|CDD\|237279	PRK13030, PRK13030, indolepyruvate ferredoxin oxidoreductase family protein.	0
CP029824.1\|AWU99000.1\|1057204_1058476_-\|MFS-transporter	gnl\|CDD\|341028	cd17475, MFS_MT3072_like, Mycobacterium tuberculosis uncharacterized MFS-type transporter MT3072 and similar transporters of the Major Facilitator Superfamily. This family includes the Mycobacterium tuberculosis uncharacterized MFS-type transporter MT3072. It belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.36272e-99
CP029824.1\|AWU99013.1\|1075520_1076540_-\|biotin-synthase-BioB	gnl\|CDD\|273075	TIGR00433, biotin_synthase, biotin synthase. Catalyzes the last step of the biotin biosynthesis pathway. All members of the seed alignment are in the immediate gene neighborhood of a bioA gene. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	3.23583e-179

>CP029824.1|AWU99006.1|1064407_1064965_+|sugar-O-acetyltransferase
MANDDRTTIIPRRTPESVAMVAEVKRAMAITARLNRLTFDDAAEVRALFSELIGTQVDDGFMLIQPFHATGGAGMKIGRNVFVNQNCTFYDLGGLEIGDDVMIGPNVSLITSGHPVEPSRRRDFVVAKPIAIERNVWIGAGATIIGGVTVGEHSVVAAGAVVTRDVPPNTLVGGNPATVIRSIAE
>CP029824.1|AWU99005.1|1063378_1063993_-|glutathione-S-transferase
MKLYYWPKTRAFRALWMLEEIGVVYELVPIDLRSHEQGSDAFVQVNPMAKLPALDDGSAPFAESGAVLLYLADRCPGAGLGIAPDDPLRGRFLQWMFFTPTCLEPAMAEKFTGASGNPVAFGWGNIARVQRALAQTLAHCPWLVGDRFTAADLLLASTLKIAFDAHLLPHEGVLGDYVARAEDRDAFRRAVAIEQREAARLLHA
>CP029824.1|AWU99004.1|1062378_1063341_+|Inward-rectifier-potassium-channel
MNVDSPSPASRGRGRKIWSGTRPVIAYGMPPLGWRDFYHRALTVSWPVFFLSLAVLFLLLNGGFAMLYMLGHAPIANQSPAGFGGAFFFSVETLATVGYGDMHPQTTYAHLVATFEIFVGMSSIALATGLVFARFSRPQAKILFARYAIVRPLNGRMTLMVRAANARQNVIAEAQAKLRLMRVEGTHEGYSLRKIHDLPLVRSEHPIFLLGWNLMHVIDESSALFGETPESLAARDASLLITIEGSDETTSQVMQARHSWAHGEIRWRHRYVDLMHDEDGITHIDYTHFHDIVPVDADTDERGSPGVVVEAGAATQGPAA
>CP029824.1|AWU99003.1|1061168_1062188_+|sulfate-ABC-transporter-substrate-binding-protein
MASIKGIGRWLHTGAAAALVVAATAAHADTSILNVSYDVTRELYKDINASFAAAYKQKTGETVALKQSHGASSAQALSVLQGLQADVVTMNQPNDIDLLAERGQLLPKDWRARFPDNSSPYSTTMVFLVRKGNPKAIKDWSDLAKPGVQVIIANPKTSGNGRYAYLAAWGFQKQKGATDQQALDFEKAIFRNVPVLDSGGRGATTTFTQRGIGDVLVTFENEVALMDTGASGAQFDAVYPSASILAEPPVAVVDKVVDKKGTRKVAQAYLDYLYTPEAQEIIAQHHLRPRDANVLKKHAAEFKSLKTFSVEQVFGSWANAQKTHFADGGTFDQVIVDRK
>CP029824.1|AWU99002.1|1059822_1060716_-|4-hydroxy-tetrahydrodipicolinate-synthase
MHTRFEGIWLPIITPFHHGEVDHAALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDAVFATLRDAAPGLPIVVGLTASATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHVEAIVDAADLPVLVYNIPYRTGVTVELETLQVLARDPRVAGIKECGGTLDRMSRLVHDTPLAILSGDDNQNFAALCAGAHGAIASSAHVLPEWHVRIHALLRDGRLADARRLSVALQPLVAALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASDGLRERLAAICTALDEIEPDLAAA
>CP029824.1|AWU99001.1|1058573_1059641_+|LysR-family-transcriptional-regulator
MVDVPRQDIPLAMPDAAQARPNFDVAALRSLVAGVDLGSFAKAAERVARSSSAVSAQIRKLEEQAGTPLFVKAGRGLALTDAGDAMLRYARRLIELNDEAAAAVRGVNLDGWVRVGLQEDFGEAILPDVLGRFARAHPKVRIEARVARNAELLDRLDANQLDLALVWGDPASAALVSRAGIDSEAIAQVPMQWIGAVGAGGFGIPDGGGEGAEDGAAPVARGETGSEAGGRAVRAPGEPLPLVVFDRPCRFFGAATDALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSHYGLPASVRVLDAASSGLPELPSLPLILLRRTSSATPTVDRLARIVTQAVRDATEGAVAALAA
>CP029824.1|AWU99000.1|1057204_1058476_-|MFS-transporter
MDTTCIASPSSPARDARGPAHRWRVLAAGVAANMSFSAAAAGIPTTAVWMRTAYHLDNGALGLVLGALGFGVALSELPWGIAADRFGDRRVLLTGLVATAAMLALMVCTIAPTAHAVPPLMRVVAMMSCVGLLGGSVNGSSGRAVMRWFGERERGLAMSIRQTAVPLGGGVGAALLPSLASHLGFAAVFGALMLLCAGSAALTWRWLHEPPAVPAAVHGTVHRPVEQQQPARHARGPLASGRVWRIVLGMGLLCTPQFAVLTFATVFLHDFGRLGLPGISAAMVALQFGAMVMRVWSGRHTDRHGNRRAYLRGSVLVAAGSFALLAAATAGSPHVPLAAIVAILVFAGICVSAWHGVAYTELATLAGANHAGTALGMANTIVYLGLFATPLAIPPLLAVSSWSVVWLAAALVAGATYPLFAAR
>CP029824.1|AWU98999.1|1056509_1057148_+|glutathione-S-transferase
MNAYRLYLSPGACSLAAHIALEETGAPFDVEIVSVQKQQNLEARYLAINAKARVPVLAIPGEPRVLTETPAILTYLARRYPDARLLPLDDPLREARCHEWLAWLVGWVHGVGYGALWRPGRFIGDPALHGAVRPHGRGTIDAANETIETALADGRTWAEPGGHSIVDPFLLVLYRWGVAIGLDMTRHPAWTAHAQREAERPAVRRALAREAG
>CP029824.1|AWU98998.1|1055477_1056398_-|LysR-family-transcriptional-regulator
MRRIHLPPLQTLRAFEAAVRLQSFTRAADALALTQGAVSQHIRTLEAQLGYPLFTRERNGATPTHAAHTLALQVRQGLSVLERAFEPTLAVRSRPRTCDVTLNVSVLPSVAERWLAPRLPRFSAAHPHIAIALHPDATLAPLRKRDRIDVALRYGPGTWPGVVAEKLMNETIFPVASPVYRNRDGVAPRAPADLVRATLLRHPAQPWEPWFQAARLDLTESARAPRFTDANALINAALKGRGVALARRSLIEPELAAGTLVRVSTVRVTDVYAHYVVWRPGHPHEAAIRTWLDWLRSEVRRRTPRR
>CP029824.1|AWU98997.1|1055032_1055317_-|hypothetical-protein
MRRVSVVVVLCAAALIAACSDDAPHDAHAADASQQAGASSGSASAFNSNATANAAASDAAPLAPPVVHYPPDDDDDAKPASNAAASATAASSPG
>CP029824.1|AWU99007.1|1066700_1070273_+|pyruvate-ferredoxin-oxidoreductase
MTARLPVDGPPALSDYRLTDNLTATRGRIFLTGTQALVRLLLMQRAVDTEQGLNTAGFVSGYRGSPLGMVDQQLWKAKKLLDGSDVRFLPAINEELGGTAVLGTQRVEADPERTVEGVYAMWYGKGPGVDRAGDALKHGNAYGSSPHGGVLVVAGDDHGCVSSSMPHQSDFAMIAWHMPVVNPANIADMLEFGLYGWALSRYSGAWVGFKAISETVESGSTVDLDGLQTQWPAPAGFTPPAGGLHNRWPDLPSLTIEARLAAKLDAVRHFARTNSIDKWIAPSAQANVGIVTCGKAHLDLMEALRRLDLTVADLDAAGVRIYKVGLSYPLEMTRIETFVDGLAEVLVIEEKGPVIEQQIKDYLYNRTEGARPRVLGKHDAAGASLLSELGELRPSRILPVFADWLARHKPALDRRERVVELVAPQILSNEADAVKRTPYFCSGCPHNTSTKVPEGSIAQAGIGCHFMASWMERDTTGLIQMGGEGVDWAAHAMFTNTKHVFQNLGDGTYFHSGILAIRQAVAAKANITYKILYNDAVAMTGGQPVDGSISVPQIARQVEAEGVSRFVVVSDEPEKYDGHHGLFPKGTTFHHRSELDTVQRELRETPGVTVLIYDQTCAAEKRRRRKKGEFPDPDKRLFINDAVCEGCGDCGVQSNCLSVEPLETPLGRKRRIDQSSCNKDYSCVNGFCPSFVTVEGAALKKAAGAAFDEAALAVRVDALPVPATHLDAAPFDMLVTGVGGTGVVTVGALISMAAHLEGKSASVLDFMGFAQKGGSVLSFVRIAASDRWLNQVRIDTQQADVLLACDMVVGASAEALQTVRHERSRIVVNTHRIPNASFVQNPDANLHADALLEKMRHAAGDGYLSSCDAQALAAKFLGDSIGANILMLGYAWQLGLVPVSLAAMMRAIELNNVAVPMNKLAFSIGRMAAGDAAGLDALWNARHAVAAHAVPETLAELIADREARLDAYGGARYVERYRALVNAARAKGDDALTRAVATTFYRLLAVKDEYEVARLYADDAFRTALEAQFEGVPGHAYRVKFNLAPPTIAKAGRDGGVPKKRVFGQWMWPVFGMLARVRSLRGTWLDPFGRTVERRMERALADDYETTLARALAATTAGNAAQVVQLADLHARVRGFGHVKVRNLAGVKRAERELALQLGIDAATSAAVQHALDEMKGAGMLKGIPVVVAK
>CP029824.1|AWU99008.1|1070357_1072025_-|Na+/H+-antiporter
MEIVFTVLILLLTVALSGAVTRNLPLQLPLPLMQIAFGAILAWPKFNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYLQRRAILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALAAVLSPTDAVALSGIAGRGRIPPQLMHILEGEALMNDASGLVALKFAIAAALTGVFSLRAASVTFVIVAAGGLATGAIVSWVFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHLDLSGVLAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVDAHHTSDALVGRMIFNVCAMMLALYAIRFLWVWLLRWFASRRAARQGLAGTMAGVRTIAVMTVGGVRGAVTLAGVLSIPVALADGAPLPGRDTAIFVASAVILGSLVVAVIGLPLLLRGVRSSRNPLADEERAARAAAAQAAIRAIDSSHDAISADLDESGAARCADISARVMDQYRRRLTALAEDGPTPRAEAKQSETMELQMRIAAVRAERSVLYRLRSESKISDETLTKLIREIDLSETALSTRKKGIL
>CP029824.1|AWU99009.1|1072321_1073608_+|EAL-domain-containing-protein
MTIVQQERPAAASPYRFEREMSSGLERLATQHRDLTLTTVFQPIFSLSHQRAVGYEALLRAHDALDRPVSPLDVFGEAARQGELLQLDRLAQALHLENFALFGAEREWLFLNVHPGVLTDPFQAAALLANLKRLGMPPRRVVLEVLEQRADDVERLAEAVREFRTHGFLIALDDFGAGHSNLERIWQLNPDIVKLDRIMLSHAAHRTGLTAILHGLVTLLHEAGKLVLVEGIETEHEAQIALSCEADFVQGYYFGRPAPGLPDSAAATSCIGELTERFRQQTEVRERRDAQRIAPYLRAFERAAERLAAGEPLDEVCWNFLALDAAARCFLLDAHGRQSGRNVVLRADRALSEARFSPLADAQGANWLRRPYFRSAIAEPGRVQVTRPYLSINEAQPCVTLSVAVRVGDAQRVLCGDIDWVDDEADAG
>CP029824.1|AWU99010.1|1073782_1074169_+|hypothetical-protein
MKRPISLTILAWVIIVTNAITCVYTPFSIGMPTTQALLSHYLLPVWATLGISVIIEAANVVIGIAILKGREWSRKAYIATSVLGFAFSFVNMPPSMFAMLIPGFLLFALFVYLLFRRPATAYFRQALA
>CP029824.1|AWU99011.1|1074165_1074570_+|hypothetical-protein
MSFVRNALAVVLFTIAGMCVIAAQMVAFTKIGHTGAMFVFVAVLFAFSAALLAAGAFAGAFRPRARGAGIAVLVATAATAFGMMGWASLLLSPGIVDVMQQQGVEVNARMFRFAPGAVATALSALAGVWLVRRG
>CP029824.1|AWU99012.1|1074653_1075379_+|copper-homeostasis-protein-CutC
MNRNAASSVLLEVIATTVGDAKAAARAGADRLELVTAITEGGLTPSVGLIEAVVAAVPIPVNVIVRPHSRSFVYDADDLRVIERDVRAAVAAGANGVVFGALDARGDVDLGALARIAAAADGRALTFHRAFDVSRDLNAAFDALLRVPAVTSVLTSGGHPSVLDAAATIARMVRQAEGATCTVLAGSGLTVDAVGDFVRATGVRAVHFGSGVRPRGEVLAPVDAQLVERVRAALDGAASHV
>CP029824.1|AWU99013.1|1075520_1076540_-|biotin-synthase-BioB
MTQAQTAAVQPDAIPVAAPAPQRWRVADVVALFALPFNDLIFRAQQLHREHFDANAVQLSTLLSIKTGGCEEDCGYCSQSSHHDTGLKAEKLMDVDTVLDAARAAKANGASRFCMGAAWRNPKERHMPALTEMVRGVKELGLETCMTLGMLEDEQAQQLADAGLDYYNHNLDTSPEFYGQVISTRTYQDRLDTLDRVRDAGINVCCGGIIGMGESRRERAGLISQLANLNPYPESVPINNLVAIEGTPLEGTAPLDPFEFVRTIAVARITMPKAVVRLSAGREQLDDAMQAMCFLAGANSMFYGDQLLTTSNPQTQRDRALFERLGIRASQADALSDNA
>CP029824.1|AWU99014.1|1076581_1077301_-|dethiobiotin-synthase
MTAPLSLFVTGTDTEIGKTFVSAAMLHGFARHGLRAAALKPVAAGAYERDGIWHNEDADQLDAAANVVLPPELRTPFLLKAPAAPHIVAAQEGVTLELDTIVACHREALTRADIVVVEGVGGFRVPLNDTQDTADLAVALGLPVVLVVGVRLGCISHALLTADAIRQRGLTLAGWVANHVDPAMSFADENVATIRDWLAREHRAPLVGRIPYMTPAAPESAAAMLDIAALVESLRTAQH
>CP029824.1|AWU99015.1|1077297_1078488_-|8-amino-7-oxononanoate-synthase
MTTSLLDTLQRGLADLDAQGLRRVRRIADTACDARMTVDGREIVGFASNDYLGLAAHPALVAAFAEGAQRYGSGSGGSHLLGGHSRAHAKLEDELAGFSGGFCDAPRALYFSTGYMANLAAMTALTGKGATIFSDALNHASLIDGMRLSRANVQVYPHADTAALAALLEASDAETKLIVSDTVFSMDGDIAPLAELVALAERHRAWLVVDDAHGFGVLGPQGRGALAAAALRSPNLVYVGTLGKAAGVAGAFVIAHETVIEWLIQRARSYIFTTAAPPAVAHAVSASLKVIAGDEGDARRAHLAALIERTRTLLRNTRWQPVDSHTAVQPLVIGSNDATLAAMRALDAHGLWVPAIRPPTVPAGTSRLRVSLSAAHSFDDLARLETALIEASEAAA
>CP029824.1|AWU99016.1|1078487_1079831_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MSTPATDDWVARSLRAVWHPCTQMKHHERLPLIPVARGAGVWLYDRDGRRYFDAISSWWVNLFGHANPDINAALKDQLDTLEHAMLAGCTHEPAIELAERLHALTARTLGHAFFASDGASAVEIALKMSFHAWRNRGRANKQEFVCVANSYHGETIGALGVTDVALFKDAYDPLIRHAHVVASPDARGALPGETAADVAGRALADVRRLFVERGDRIAALIVEPLVQCAAGMAMHDPSYVRGLRALCDEFGVHLIADEIAVGCGRTGTFFACEQAGVWPDFMCLSKGISGGYLPLSLVLTRDDVFAAFYDDDTTRGFLHSHSYTGNPLACRAAVATLDLFSRDDVLAQNARKSAAMRAALAPLDAHPQVRHLRERGTLFAFDVALDGDAARGFSRRFFERALERELLLRPIGTTVYLMPPYVMSDDDIAWLAQHTRDTLDATLAEIA

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Crispr_ID: CP029824_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029824_4

1065889-1066364

Orphan

Consensus_repeat	Method
CACTCGAAGCGCTGTGGTTTTCAACGGTGAG	CRISPRCasFinder

5 spacers

The CRISPR arrays of CP029824_4

>merge|CP029824|4|1065889-1066364|CRISPRCasFinder
CACTCGAAGCGCTGTGGTTTTCAACGGTGAGGGTGCGTGCGAGACCGGACGGCAGCGTCGGTTCGAGCATGGACAACCGCCGCCGCAACCACTCGAAGCCCTGTGGTTTTCAACGGTGAGTGCAGGCCTGCGATTGCGCAGCGGACGTGTTCCGGTGTGAATATCCGGCCAACGAACCCACTCGCGCTCCTGTGTATTCGATCGGTGAGGGTGAACGGCGGATCGACGAAACGAGCCGATCCCGATGTGGATATCCACCGCCGAAATCCACTCGCCGCGCTGTGAATCTCAACGGTGAGCATCGGCGCCCGAGTGAACCGGATACCGATTTCGGATGTGGACATCCCGGCCCCAACGCCACTCGAAACGCTGTGCATTCGAACGGTGAGCGCACGAGCCCGATCGGCCGAAGGGCGCAGCATTGTGGACATCCCGCGCTCCCGACCAATCGGAATGCTGTGCATTTCAATGGTGAG

>CP029824|4|4|1065889-1066364|CRISPRCasFinder
CACTCGAAGCGCTGTGGTTTTCAACGGTGAG	GGTGCGTGCGAGACCGGACGGCAGCGTCGGTTCGAGCATGGACAACCGCCGCCGCAAC
CACTCGAAGCCCTGTGGTTTTCAACGGTGAG	TGCAGGCCTGCGATTGCGCAGCGGACGTGTTCCGGTGTGAATATCCGGCCAACGAACC
CACTCGCGCTCCTGTGTATTCGATCGGTGAG	GGTGAACGGCGGATCGACGAAACGAGCCGATCCCGATGTGGATATCCACCGCCGAAATC
CACTCGCCGCGCTGTGAATCTCAACGGTGAG	CATCGGCGCCCGAGTGAACCGGATACCGATTTCGGATGTGGACATCCCGGCCCCAACGC
CACTCGAAACGCTGTGCATTCGAACGGTGAG	CGCACGAGCCCGATCGGCCGAAGGGCGCAGCATTGTGGACATCCCGCGCTCCCGAC
CAATCGGAATGCTGTGCATTTCAATGGTGAG

Protein	Signature genes	Signature genes Name	Protein_function
CP029824.1\|AWU99001.1\|1058573_1059641_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237907
CP029824.1\|AWU98998.1\|1055477_1056398_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990
CP029824.1\|AWU99004.1\|1062378_1063341_+\|Inward-rectifier-potassium-channel	unknown	unknown	gnl\|CDD\|375232
CP029824.1\|AWU98997.1\|1055032_1055317_-\|hypothetical-protein	unknown	unknown	unknown
CP029824.1\|AWU99005.1\|1063378_1063993_-\|glutathione-S-transferase	unknown	unknown	gnl\|CDD\|239344
CP029824.1\|AWU99015.1\|1077297_1078488_-\|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl\|CDD\|235655
CP029824.1\|AWU99014.1\|1076581_1077301_-\|dethiobiotin-synthase	unknown	unknown	gnl\|CDD\|234625
CP029824.1\|AWU99010.1\|1073782_1074169_+\|hypothetical-protein	unknown	unknown	unknown
CP029824.1\|AWU99003.1\|1061168_1062188_+\|sulfate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224529
CP029824.1\|AWU98999.1\|1056509_1057148_+\|glutathione-S-transferase	unknown	unknown	gnl\|CDD\|182533
CP029824.1\|AWU99011.1\|1074165_1074570_+\|hypothetical-protein	unknown	unknown	unknown
CP029824.1\|AWU99002.1\|1059822_1060716_-\|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl\|CDD\|188637
CP029824.1\|AWU99006.1\|1064407_1064965_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
CP029824.1\|AWU99008.1\|1070357_1072025_-\|Na+/H+-antiporter	unknown	unknown	gnl\|CDD\|129911
CP029824.1\|AWU99000.1\|1057204_1058476_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341028
CP029824.1\|AWU99012.1\|1074653_1075379_+\|copper-homeostasis-protein-CutC	unknown	unknown	gnl\|CDD\|225684
CP029824.1\|AWU99007.1\|1066700_1070273_+\|pyruvate-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|237279
CP029824.1\|AWU99016.1\|1078487_1079831_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|235894
CP029824.1\|AWU99013.1\|1075520_1076540_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|273075
CP029824.1\|AWU99009.1\|1072321_1073608_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923

Protein	Function_ID	Function_description	E-value
CP029824.1\|AWU99001.1\|1058573_1059641_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|237907	PRK15092, PRK15092, DNA-binding transcriptional repressor LrhA; Provisional.	2.46205e-58
CP029824.1\|AWU98998.1\|1055477_1056398_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	1.94781e-76
CP029824.1\|AWU99004.1\|1062378_1063341_+\|Inward-rectifier-potassium-channel	gnl\|CDD\|375232	pfam17655, IRK_C, Inward rectifier potassium channel C-terminal domain. This cytoplasmic C-terminal domain has an Ig fold.	1.15568e-30
CP029824.1\|AWU99009.1\|1072321_1073608_+\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.3686e-60
CP029824.1\|AWU99005.1\|1063378_1063993_-\|glutathione-S-transferase	gnl\|CDD\|239344	cd03046, GST_N_GTT1_like, GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress. GSTs also show GSH peroxidase activity and are involved in the synthesis of prostaglandins and leukotrienes. The GST fold contains an N-terminal TRX-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GTT1, a homodimer, exhibits GST activity with standard substrates and associates with the endoplasmic reticulum. Its expression is induced after diauxic shift and remains high throughout the stationary phase. S. pombe GST-III is implicated in the detoxification of various metals.	5.31095e-29
CP029824.1\|AWU99015.1\|1077297_1078488_-\|8-amino-7-oxononanoate-synthase	gnl\|CDD\|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	0
CP029824.1\|AWU99014.1\|1076581_1077301_-\|dethiobiotin-synthase	gnl\|CDD\|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	1.23677e-91
CP029824.1\|AWU99016.1\|1078487_1079831_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|235894	PRK06943, PRK06943, adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional.	0
CP029824.1\|AWU99003.1\|1061168_1062188_+\|sulfate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224529	COG1613, Sbp, ABC-type sulfate transport system, periplasmic component [Inorganic ion transport and metabolism].	2.98462e-171
CP029824.1\|AWU98999.1\|1056509_1057148_+\|glutathione-S-transferase	gnl\|CDD\|182533	PRK10542, PRK10542, glutathionine S-transferase; Provisional.	2.11045e-29
CP029824.1\|AWU99002.1\|1059822_1060716_-\|4-hydroxy-tetrahydrodipicolinate-synthase	gnl\|CDD\|188637	cd00950, DHDPS, Dihydrodipicolinate synthase (DHDPS). Dihydrodipicolinate synthase (DHDPS) is a key enzyme in lysine biosynthesis. It catalyzes the aldol condensation of L-aspartate-beta- semialdehyde and pyruvate to dihydropicolinic acid via a Schiff base formation between pyruvate and a lysine residue. The functional enzyme is a homotetramer consisting of a dimer of dimers. DHDPS is member of dihydrodipicolinate synthase family that comprises several pyruvate-dependent class I aldolases that use the same catalytic step to catalyze different reactions in different pathways.	7.26353e-114
CP029824.1\|AWU99006.1\|1064407_1064965_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	2.09017e-62
CP029824.1\|AWU99012.1\|1074653_1075379_+\|copper-homeostasis-protein-CutC	gnl\|CDD\|225684	COG3142, CutC, Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism].	5.78483e-57
CP029824.1\|AWU99008.1\|1070357_1072025_-\|Na+/H+-antiporter	gnl\|CDD\|129911	TIGR00831, Putative_Na+/H+_exchanger_Rv2287/MT2345/Mb2309., Na+/H+ antiporter, bacterial form. The Monovalent Cation:Proton Antiporter-1 (CPA1) Family (TC 2.A.36) The CPA1 family is a large family of proteins derived from Gram-positive and Gram-negative bacteria, blue green bacteria, yeast, plants and animals. Transporters from eukaryotes have been functionally characterized, and all of these catalyze Na+:H+ exchange. Their primary physiological functions may be in (1) cytoplasmic pH regulation, extruding the H+ generated during metabolism, and (2) salt tolerance (in plants), due to Na+ uptake into vacuoles. This model is specific for the bacterial members of this family. [Transport and binding proteins, Cations and iron carrying compounds].	6.81783e-116
CP029824.1\|AWU99007.1\|1066700_1070273_+\|pyruvate-ferredoxin-oxidoreductase	gnl\|CDD\|237279	PRK13030, PRK13030, indolepyruvate ferredoxin oxidoreductase family protein.	0
CP029824.1\|AWU99000.1\|1057204_1058476_-\|MFS-transporter	gnl\|CDD\|341028	cd17475, MFS_MT3072_like, Mycobacterium tuberculosis uncharacterized MFS-type transporter MT3072 and similar transporters of the Major Facilitator Superfamily. This family includes the Mycobacterium tuberculosis uncharacterized MFS-type transporter MT3072. It belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.36272e-99
CP029824.1\|AWU99013.1\|1075520_1076540_-\|biotin-synthase-BioB	gnl\|CDD\|273075	TIGR00433, biotin_synthase, biotin synthase. Catalyzes the last step of the biotin biosynthesis pathway. All members of the seed alignment are in the immediate gene neighborhood of a bioA gene. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	3.23583e-179

>CP029824.1|AWU99006.1|1064407_1064965_+|sugar-O-acetyltransferase
MANDDRTTIIPRRTPESVAMVAEVKRAMAITARLNRLTFDDAAEVRALFSELIGTQVDDGFMLIQPFHATGGAGMKIGRNVFVNQNCTFYDLGGLEIGDDVMIGPNVSLITSGHPVEPSRRRDFVVAKPIAIERNVWIGAGATIIGGVTVGEHSVVAAGAVVTRDVPPNTLVGGNPATVIRSIAE
>CP029824.1|AWU99005.1|1063378_1063993_-|glutathione-S-transferase
MKLYYWPKTRAFRALWMLEEIGVVYELVPIDLRSHEQGSDAFVQVNPMAKLPALDDGSAPFAESGAVLLYLADRCPGAGLGIAPDDPLRGRFLQWMFFTPTCLEPAMAEKFTGASGNPVAFGWGNIARVQRALAQTLAHCPWLVGDRFTAADLLLASTLKIAFDAHLLPHEGVLGDYVARAEDRDAFRRAVAIEQREAARLLHA
>CP029824.1|AWU99004.1|1062378_1063341_+|Inward-rectifier-potassium-channel
MNVDSPSPASRGRGRKIWSGTRPVIAYGMPPLGWRDFYHRALTVSWPVFFLSLAVLFLLLNGGFAMLYMLGHAPIANQSPAGFGGAFFFSVETLATVGYGDMHPQTTYAHLVATFEIFVGMSSIALATGLVFARFSRPQAKILFARYAIVRPLNGRMTLMVRAANARQNVIAEAQAKLRLMRVEGTHEGYSLRKIHDLPLVRSEHPIFLLGWNLMHVIDESSALFGETPESLAARDASLLITIEGSDETTSQVMQARHSWAHGEIRWRHRYVDLMHDEDGITHIDYTHFHDIVPVDADTDERGSPGVVVEAGAATQGPAA
>CP029824.1|AWU99003.1|1061168_1062188_+|sulfate-ABC-transporter-substrate-binding-protein
MASIKGIGRWLHTGAAAALVVAATAAHADTSILNVSYDVTRELYKDINASFAAAYKQKTGETVALKQSHGASSAQALSVLQGLQADVVTMNQPNDIDLLAERGQLLPKDWRARFPDNSSPYSTTMVFLVRKGNPKAIKDWSDLAKPGVQVIIANPKTSGNGRYAYLAAWGFQKQKGATDQQALDFEKAIFRNVPVLDSGGRGATTTFTQRGIGDVLVTFENEVALMDTGASGAQFDAVYPSASILAEPPVAVVDKVVDKKGTRKVAQAYLDYLYTPEAQEIIAQHHLRPRDANVLKKHAAEFKSLKTFSVEQVFGSWANAQKTHFADGGTFDQVIVDRK
>CP029824.1|AWU99002.1|1059822_1060716_-|4-hydroxy-tetrahydrodipicolinate-synthase
MHTRFEGIWLPIITPFHHGEVDHAALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDAVFATLRDAAPGLPIVVGLTASATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHVEAIVDAADLPVLVYNIPYRTGVTVELETLQVLARDPRVAGIKECGGTLDRMSRLVHDTPLAILSGDDNQNFAALCAGAHGAIASSAHVLPEWHVRIHALLRDGRLADARRLSVALQPLVAALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASDGLRERLAAICTALDEIEPDLAAA
>CP029824.1|AWU99001.1|1058573_1059641_+|LysR-family-transcriptional-regulator
MVDVPRQDIPLAMPDAAQARPNFDVAALRSLVAGVDLGSFAKAAERVARSSSAVSAQIRKLEEQAGTPLFVKAGRGLALTDAGDAMLRYARRLIELNDEAAAAVRGVNLDGWVRVGLQEDFGEAILPDVLGRFARAHPKVRIEARVARNAELLDRLDANQLDLALVWGDPASAALVSRAGIDSEAIAQVPMQWIGAVGAGGFGIPDGGGEGAEDGAAPVARGETGSEAGGRAVRAPGEPLPLVVFDRPCRFFGAATDALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSHYGLPASVRVLDAASSGLPELPSLPLILLRRTSSATPTVDRLARIVTQAVRDATEGAVAALAA
>CP029824.1|AWU99000.1|1057204_1058476_-|MFS-transporter
MDTTCIASPSSPARDARGPAHRWRVLAAGVAANMSFSAAAAGIPTTAVWMRTAYHLDNGALGLVLGALGFGVALSELPWGIAADRFGDRRVLLTGLVATAAMLALMVCTIAPTAHAVPPLMRVVAMMSCVGLLGGSVNGSSGRAVMRWFGERERGLAMSIRQTAVPLGGGVGAALLPSLASHLGFAAVFGALMLLCAGSAALTWRWLHEPPAVPAAVHGTVHRPVEQQQPARHARGPLASGRVWRIVLGMGLLCTPQFAVLTFATVFLHDFGRLGLPGISAAMVALQFGAMVMRVWSGRHTDRHGNRRAYLRGSVLVAAGSFALLAAATAGSPHVPLAAIVAILVFAGICVSAWHGVAYTELATLAGANHAGTALGMANTIVYLGLFATPLAIPPLLAVSSWSVVWLAAALVAGATYPLFAAR
>CP029824.1|AWU98999.1|1056509_1057148_+|glutathione-S-transferase
MNAYRLYLSPGACSLAAHIALEETGAPFDVEIVSVQKQQNLEARYLAINAKARVPVLAIPGEPRVLTETPAILTYLARRYPDARLLPLDDPLREARCHEWLAWLVGWVHGVGYGALWRPGRFIGDPALHGAVRPHGRGTIDAANETIETALADGRTWAEPGGHSIVDPFLLVLYRWGVAIGLDMTRHPAWTAHAQREAERPAVRRALAREAG
>CP029824.1|AWU98998.1|1055477_1056398_-|LysR-family-transcriptional-regulator
MRRIHLPPLQTLRAFEAAVRLQSFTRAADALALTQGAVSQHIRTLEAQLGYPLFTRERNGATPTHAAHTLALQVRQGLSVLERAFEPTLAVRSRPRTCDVTLNVSVLPSVAERWLAPRLPRFSAAHPHIAIALHPDATLAPLRKRDRIDVALRYGPGTWPGVVAEKLMNETIFPVASPVYRNRDGVAPRAPADLVRATLLRHPAQPWEPWFQAARLDLTESARAPRFTDANALINAALKGRGVALARRSLIEPELAAGTLVRVSTVRVTDVYAHYVVWRPGHPHEAAIRTWLDWLRSEVRRRTPRR
>CP029824.1|AWU98997.1|1055032_1055317_-|hypothetical-protein
MRRVSVVVVLCAAALIAACSDDAPHDAHAADASQQAGASSGSASAFNSNATANAAASDAAPLAPPVVHYPPDDDDDAKPASNAAASATAASSPG
>CP029824.1|AWU99007.1|1066700_1070273_+|pyruvate-ferredoxin-oxidoreductase
MTARLPVDGPPALSDYRLTDNLTATRGRIFLTGTQALVRLLLMQRAVDTEQGLNTAGFVSGYRGSPLGMVDQQLWKAKKLLDGSDVRFLPAINEELGGTAVLGTQRVEADPERTVEGVYAMWYGKGPGVDRAGDALKHGNAYGSSPHGGVLVVAGDDHGCVSSSMPHQSDFAMIAWHMPVVNPANIADMLEFGLYGWALSRYSGAWVGFKAISETVESGSTVDLDGLQTQWPAPAGFTPPAGGLHNRWPDLPSLTIEARLAAKLDAVRHFARTNSIDKWIAPSAQANVGIVTCGKAHLDLMEALRRLDLTVADLDAAGVRIYKVGLSYPLEMTRIETFVDGLAEVLVIEEKGPVIEQQIKDYLYNRTEGARPRVLGKHDAAGASLLSELGELRPSRILPVFADWLARHKPALDRRERVVELVAPQILSNEADAVKRTPYFCSGCPHNTSTKVPEGSIAQAGIGCHFMASWMERDTTGLIQMGGEGVDWAAHAMFTNTKHVFQNLGDGTYFHSGILAIRQAVAAKANITYKILYNDAVAMTGGQPVDGSISVPQIARQVEAEGVSRFVVVSDEPEKYDGHHGLFPKGTTFHHRSELDTVQRELRETPGVTVLIYDQTCAAEKRRRRKKGEFPDPDKRLFINDAVCEGCGDCGVQSNCLSVEPLETPLGRKRRIDQSSCNKDYSCVNGFCPSFVTVEGAALKKAAGAAFDEAALAVRVDALPVPATHLDAAPFDMLVTGVGGTGVVTVGALISMAAHLEGKSASVLDFMGFAQKGGSVLSFVRIAASDRWLNQVRIDTQQADVLLACDMVVGASAEALQTVRHERSRIVVNTHRIPNASFVQNPDANLHADALLEKMRHAAGDGYLSSCDAQALAAKFLGDSIGANILMLGYAWQLGLVPVSLAAMMRAIELNNVAVPMNKLAFSIGRMAAGDAAGLDALWNARHAVAAHAVPETLAELIADREARLDAYGGARYVERYRALVNAARAKGDDALTRAVATTFYRLLAVKDEYEVARLYADDAFRTALEAQFEGVPGHAYRVKFNLAPPTIAKAGRDGGVPKKRVFGQWMWPVFGMLARVRSLRGTWLDPFGRTVERRMERALADDYETTLARALAATTAGNAAQVVQLADLHARVRGFGHVKVRNLAGVKRAERELALQLGIDAATSAAVQHALDEMKGAGMLKGIPVVVAK
>CP029824.1|AWU99008.1|1070357_1072025_-|Na+/H+-antiporter
MEIVFTVLILLLTVALSGAVTRNLPLQLPLPLMQIAFGAILAWPKFNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYLQRRAILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALAAVLSPTDAVALSGIAGRGRIPPQLMHILEGEALMNDASGLVALKFAIAAALTGVFSLRAASVTFVIVAAGGLATGAIVSWVFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHLDLSGVLAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVDAHHTSDALVGRMIFNVCAMMLALYAIRFLWVWLLRWFASRRAARQGLAGTMAGVRTIAVMTVGGVRGAVTLAGVLSIPVALADGAPLPGRDTAIFVASAVILGSLVVAVIGLPLLLRGVRSSRNPLADEERAARAAAAQAAIRAIDSSHDAISADLDESGAARCADISARVMDQYRRRLTALAEDGPTPRAEAKQSETMELQMRIAAVRAERSVLYRLRSESKISDETLTKLIREIDLSETALSTRKKGIL
>CP029824.1|AWU99009.1|1072321_1073608_+|EAL-domain-containing-protein
MTIVQQERPAAASPYRFEREMSSGLERLATQHRDLTLTTVFQPIFSLSHQRAVGYEALLRAHDALDRPVSPLDVFGEAARQGELLQLDRLAQALHLENFALFGAEREWLFLNVHPGVLTDPFQAAALLANLKRLGMPPRRVVLEVLEQRADDVERLAEAVREFRTHGFLIALDDFGAGHSNLERIWQLNPDIVKLDRIMLSHAAHRTGLTAILHGLVTLLHEAGKLVLVEGIETEHEAQIALSCEADFVQGYYFGRPAPGLPDSAAATSCIGELTERFRQQTEVRERRDAQRIAPYLRAFERAAERLAAGEPLDEVCWNFLALDAAARCFLLDAHGRQSGRNVVLRADRALSEARFSPLADAQGANWLRRPYFRSAIAEPGRVQVTRPYLSINEAQPCVTLSVAVRVGDAQRVLCGDIDWVDDEADAG
>CP029824.1|AWU99010.1|1073782_1074169_+|hypothetical-protein
MKRPISLTILAWVIIVTNAITCVYTPFSIGMPTTQALLSHYLLPVWATLGISVIIEAANVVIGIAILKGREWSRKAYIATSVLGFAFSFVNMPPSMFAMLIPGFLLFALFVYLLFRRPATAYFRQALA
>CP029824.1|AWU99011.1|1074165_1074570_+|hypothetical-protein
MSFVRNALAVVLFTIAGMCVIAAQMVAFTKIGHTGAMFVFVAVLFAFSAALLAAGAFAGAFRPRARGAGIAVLVATAATAFGMMGWASLLLSPGIVDVMQQQGVEVNARMFRFAPGAVATALSALAGVWLVRRG
>CP029824.1|AWU99012.1|1074653_1075379_+|copper-homeostasis-protein-CutC
MNRNAASSVLLEVIATTVGDAKAAARAGADRLELVTAITEGGLTPSVGLIEAVVAAVPIPVNVIVRPHSRSFVYDADDLRVIERDVRAAVAAGANGVVFGALDARGDVDLGALARIAAAADGRALTFHRAFDVSRDLNAAFDALLRVPAVTSVLTSGGHPSVLDAAATIARMVRQAEGATCTVLAGSGLTVDAVGDFVRATGVRAVHFGSGVRPRGEVLAPVDAQLVERVRAALDGAASHV
>CP029824.1|AWU99013.1|1075520_1076540_-|biotin-synthase-BioB
MTQAQTAAVQPDAIPVAAPAPQRWRVADVVALFALPFNDLIFRAQQLHREHFDANAVQLSTLLSIKTGGCEEDCGYCSQSSHHDTGLKAEKLMDVDTVLDAARAAKANGASRFCMGAAWRNPKERHMPALTEMVRGVKELGLETCMTLGMLEDEQAQQLADAGLDYYNHNLDTSPEFYGQVISTRTYQDRLDTLDRVRDAGINVCCGGIIGMGESRRERAGLISQLANLNPYPESVPINNLVAIEGTPLEGTAPLDPFEFVRTIAVARITMPKAVVRLSAGREQLDDAMQAMCFLAGANSMFYGDQLLTTSNPQTQRDRALFERLGIRASQADALSDNA
>CP029824.1|AWU99014.1|1076581_1077301_-|dethiobiotin-synthase
MTAPLSLFVTGTDTEIGKTFVSAAMLHGFARHGLRAAALKPVAAGAYERDGIWHNEDADQLDAAANVVLPPELRTPFLLKAPAAPHIVAAQEGVTLELDTIVACHREALTRADIVVVEGVGGFRVPLNDTQDTADLAVALGLPVVLVVGVRLGCISHALLTADAIRQRGLTLAGWVANHVDPAMSFADENVATIRDWLAREHRAPLVGRIPYMTPAAPESAAAMLDIAALVESLRTAQH
>CP029824.1|AWU99015.1|1077297_1078488_-|8-amino-7-oxononanoate-synthase
MTTSLLDTLQRGLADLDAQGLRRVRRIADTACDARMTVDGREIVGFASNDYLGLAAHPALVAAFAEGAQRYGSGSGGSHLLGGHSRAHAKLEDELAGFSGGFCDAPRALYFSTGYMANLAAMTALTGKGATIFSDALNHASLIDGMRLSRANVQVYPHADTAALAALLEASDAETKLIVSDTVFSMDGDIAPLAELVALAERHRAWLVVDDAHGFGVLGPQGRGALAAAALRSPNLVYVGTLGKAAGVAGAFVIAHETVIEWLIQRARSYIFTTAAPPAVAHAVSASLKVIAGDEGDARRAHLAALIERTRTLLRNTRWQPVDSHTAVQPLVIGSNDATLAAMRALDAHGLWVPAIRPPTVPAGTSRLRVSLSAAHSFDDLARLETALIEASEAAA
>CP029824.1|AWU99016.1|1078487_1079831_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MSTPATDDWVARSLRAVWHPCTQMKHHERLPLIPVARGAGVWLYDRDGRRYFDAISSWWVNLFGHANPDINAALKDQLDTLEHAMLAGCTHEPAIELAERLHALTARTLGHAFFASDGASAVEIALKMSFHAWRNRGRANKQEFVCVANSYHGETIGALGVTDVALFKDAYDPLIRHAHVVASPDARGALPGETAADVAGRALADVRRLFVERGDRIAALIVEPLVQCAAGMAMHDPSYVRGLRALCDEFGVHLIADEIAVGCGRTGTFFACEQAGVWPDFMCLSKGISGGYLPLSLVLTRDDVFAAFYDDDTTRGFLHSHSYTGNPLACRAAVATLDLFSRDDVLAQNARKSAAMRAALAPLDAHPQVRHLRERGTLFAFDVALDGDAARGFSRRFFERALERELLLRPIGTTVYLMPPYVMSDDDIAWLAQHTRDTLDATLAEIA

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Crispr_ID: CP029824_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029824_6

1865686-1865758

Orphan

Consensus_repeat	Method
CGACCGCGAAGCATGGGATCGGAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029824_6

>merge|CP029824|6|1865686-1865758|CRISPRCasFinder
CGACCGCGAAGCATGGGATCGGAGCAAGTGCTAAAGCGCTAACTCCGGTCGACCGCGAAGCATGGGACCGGAG

>CP029824|6|5|1865686-1865758|CRISPRCasFinder
CGACCGCGAAGCATGGGATCGGAG	CAAGTGCTAAAGCGCTAACTCCGGT
CGACCGCGAAGCATGGGACCGGAG

Protein	Signature genes	Signature genes Name	Protein_function
CP029824.1\|AWV01276.1\|1868195_1868657_+\|dehydratase	unknown	unknown	gnl\|CDD\|239538
CP029824.1\|AWU99664.1\|1865801_1866998_+\|pimeloyl-CoA-dehydrogenase-large-subunit	unknown	unknown	gnl\|CDD\|132248
CP029824.1\|AWU99654.1\|1856397_1857465_+\|NADH-quinone-oxidoreductase-subunit-NuoH	unknown	unknown	gnl\|CDD\|235692
CP029824.1\|AWU99662.1\|1864450_1865041_+\|ADP-ribose-pyrophosphatase	unknown	unknown	gnl\|CDD\|239516
CP029824.1\|AWU99671.1\|1873027_1873525_-\|putative-toxin-antitoxin-system-toxin-component,-PIN-family	unknown	unknown	gnl\|CDD\|379205
CP029824.1\|AWU99672.1\|1873581_1874364_+\|peroxide-stress-protein-YaaA	unknown	unknown	gnl\|CDD\|234999
CP029824.1\|AWU99665.1\|1867023_1868157_+\|pimeloyl-CoA-dehydrogenase-small-subunit	unknown	unknown	gnl\|CDD\|132247
CP029824.1\|AWU99666.1\|1868653_1869130_+\|MaoC-family-dehydratase	unknown	unknown	gnl\|CDD\|239534
CP029824.1\|AWU99660.1\|1862648_1864118_+\|NADH-quinone-oxidoreductase-subunit-NuoN	unknown	unknown	gnl\|CDD\|235603
CP029824.1\|AWU99667.1\|1869177_1869870_-\|glutathione-S-transferase-family-protein	unknown	unknown	gnl\|CDD\|183298
CP029824.1\|AWU99669.1\|1871120_1871777_+\|glutathione-S-transferase	unknown	unknown	gnl\|CDD\|198344
CP029824.1\|AWU99657.1\|1858737_1859043_+\|NADH-quinone-oxidoreductase-subunit-NuoK	unknown	unknown	gnl\|CDD\|180218
CP029824.1\|AWU99670.1\|1871821_1872994_-\|methionine-aminotransferase	unknown	unknown	gnl\|CDD\|181642
CP029824.1\|AWU99668.1\|1870127_1870919_-\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|181009
CP029824.1\|AWU99656.1\|1858069_1858720_+\|NADH-quinone-oxidoreductase-subunit-J	unknown	unknown	gnl\|CDD\|235844
CP029824.1\|AWU99659.1\|1861133_1862624_+\|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl\|CDD\|235622
CP029824.1\|AWU99661.1\|1864117_1864414_+\|DUF2818-domain-containing-protein	unknown	unknown	gnl\|CDD\|378532
CP029824.1\|AWU99663.1\|1865177_1865600_+\|DUF1178-family-protein	unknown	unknown	gnl\|CDD\|377685
CP029824.1\|AWU99658.1\|1859060_1861115_+\|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl\|CDD\|235836
CP029824.1\|AWU99655.1\|1857477_1857966_+\|NADH-quinone-oxidoreductase-subunit-I	unknown	unknown	gnl\|CDD\|235637

Protein	Function_ID	Function_description	E-value
CP029824.1\|AWV01276.1\|1868195_1868657_+\|dehydratase	gnl\|CDD\|239538	cd03454, YdeM, YdeM is a Bacillus subtilis protein that belongs to a family of prokaryotic proteins of unkown function. YdeM has sequence similarity to the hot-dog fold of (R)-specific enoyl-CoA hydratase. Other enzymes with this fold include the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.	5.86093e-72
CP029824.1\|AWU99664.1\|1865801_1866998_+\|pimeloyl-CoA-dehydrogenase-large-subunit	gnl\|CDD\|132248	TIGR03204, pimC_large, pimeloyl-CoA dehydrogenase, large subunit. Members of this protein family are the PimC proteins of species such as Rhodopseudomonas palustris and Bradyrhizobium japonicum. The pimFABCDE operon encodes proteins for the metabolism of straight chain dicarboxylates of seven to fourteen carbons. Especially relevant is pimeloyl-CoA, basis of the gene symbol, as it is a catabolite of benzoyl-CoA degradation, which occurs in Rhodopseudomonas palustris.	1.56055e-175
CP029824.1\|AWU99654.1\|1856397_1857465_+\|NADH-quinone-oxidoreductase-subunit-NuoH	gnl\|CDD\|235692	PRK06076, PRK06076, NADH-quinone oxidoreductase subunit NuoH.	1.51757e-153
CP029824.1\|AWU99662.1\|1864450_1865041_+\|ADP-ribose-pyrophosphatase	gnl\|CDD\|239516	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, for its activity. It also contains a highly conserved 23-residue Nudix motif (GX5EX7REUXEEXGU, where U = I, L or V) which functions as a metal binding site/catalytic site. In addition to the Nudix motif, there are additional conserved amino acid residues, distal from the signature sequence, that correlate with substrate specificity. In humans, there are four distinct ADPRase activities, three putative cytosolic enzymes (ADPRase-I, -II, and -Mn) and a single mitochondrial enzyme (ADPRase-m). Human ADPRase-II is also referred to as NUDT5. It lacks the N-terminal target sequence unique to mitochondrial ADPRase. The different cytosolic types are distinguished by their specificities for substrate and specific requirement for metal ions. NUDT5 forms a homodimer.	7.71162e-47
CP029824.1\|AWU99671.1\|1873027_1873525_-\|putative-toxin-antitoxin-system-toxin-component,-PIN-family	gnl\|CDD\|379205	pfam13470, PIN_3, PIN domain. Members of this family of bacterial domains are predicted to be RNases (from similarities to 5'-exonucleases).	9.28616e-26
CP029824.1\|AWU99672.1\|1873581_1874364_+\|peroxide-stress-protein-YaaA	gnl\|CDD\|234999	PRK02101, PRK02101, peroxide stress protein YaaA.	5.38079e-144
CP029824.1\|AWU99665.1\|1867023_1868157_+\|pimeloyl-CoA-dehydrogenase-small-subunit	gnl\|CDD\|132247	TIGR03203, pimD_small, pimeloyl-CoA dehydrogenase, small subunit. Members of this protein family are the PimD proteins of species such as Rhodopseudomonas palustris, Bradyrhizobium japonicum. The pimFABCDE operon encodes proteins for the metabolism of straight chain dicarboxylates of seven to fourteen carbons. Especially relevant is pimeloyl-CoA, basis of the gene symbol, as it is a catabolite of benzoyl-CoA degradation, which occurs in Rhodopseudomonas palustris.	4.56615e-93
CP029824.1\|AWU99666.1\|1868653_1869130_+\|MaoC-family-dehydratase	gnl\|CDD\|239534	cd03450, NodN, NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. Rhizobium and related species form nodules on the roots of their legume hosts, a symbiotic process that requires production of Nod factors, which are signal molecules involved in root hair deformation and meristematic cell division. The nodulation gene products, including NodN, are involved in producing the Nod factors, however the role played by NodN is unclear.	2.76974e-73
CP029824.1\|AWU99660.1\|1862648_1864118_+\|NADH-quinone-oxidoreductase-subunit-NuoN	gnl\|CDD\|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	0
CP029824.1\|AWU99667.1\|1869177_1869870_-\|glutathione-S-transferase-family-protein	gnl\|CDD\|183298	PRK11752, PRK11752, putative S-transferase; Provisional.	5.94401e-85
CP029824.1\|AWU99669.1\|1871120_1871777_+\|glutathione-S-transferase	gnl\|CDD\|198344	cd10424, GST_C_9, C-terminal, alpha helical domain of an unknown subfamily 9 of Glutathione S-transferases. Glutathione S-transferase (GST) C-terminal domain family, unknown subfamily 9; composed of uncharacterized proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. GSTs also show GSH peroxidase activity and are involved in the synthesis of prostaglandins and leukotrienes. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain.	5.20481e-38
CP029824.1\|AWU99657.1\|1858737_1859043_+\|NADH-quinone-oxidoreductase-subunit-NuoK	gnl\|CDD\|180218	PRK05715, PRK05715, NADH-quinone oxidoreductase subunit NuoK.	1.31987e-40
CP029824.1\|AWU99670.1\|1871821_1872994_-\|methionine-aminotransferase	gnl\|CDD\|181642	PRK09082, PRK09082, methionine aminotransferase; Validated.	0
CP029824.1\|AWU99668.1\|1870127_1870919_-\|enoyl-CoA-hydratase	gnl\|CDD\|181009	PRK07511, PRK07511, enoyl-CoA hydratase; Provisional.	2.81275e-153
CP029824.1\|AWU99656.1\|1858069_1858720_+\|NADH-quinone-oxidoreductase-subunit-J	gnl\|CDD\|235844	PRK06638, PRK06638, NADH-quinone oxidoreductase subunit J.	2.76085e-71
CP029824.1\|AWU99659.1\|1861133_1862624_+\|NADH-quinone-oxidoreductase-subunit-M	gnl\|CDD\|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	0
CP029824.1\|AWU99661.1\|1864117_1864414_+\|DUF2818-domain-containing-protein	gnl\|CDD\|378532	pfam10993, DUF2818, Protein of unknown function (DUF2818). This bacterial family of proteins has no known function.	7.5073e-39
CP029824.1\|AWU99663.1\|1865177_1865600_+\|DUF1178-family-protein	gnl\|CDD\|377685	pfam06676, DUF1178, Protein of unknown function (DUF1178). This family consists of several hypothetical bacterial proteins of around 150 residues in length. The function of this family is unknown.	9.69964e-70
CP029824.1\|AWU99658.1\|1859060_1861115_+\|NADH-quinone-oxidoreductase-subunit-L	gnl\|CDD\|235836	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed.	0
CP029824.1\|AWU99655.1\|1857477_1857966_+\|NADH-quinone-oxidoreductase-subunit-I	gnl\|CDD\|235637	PRK05888, PRK05888, NADH-quinone oxidoreductase subunit NuoI.	3.02681e-90

>CP029824.1|AWU99663.1|1865177_1865600_+|DUF1178-family-protein
MKVLDLQCPHGHRFEGWFASADEFEAQLSRKLVECPVCGTTEVNRLPSAPRLNLSGATQAQPADPRALQAQVMRALREVLEKTENVGERFAEEARRIHYNEAPARSIRGVTTPEDAQSLVEEGIDVMPLPIPAALKEPLQ
>CP029824.1|AWU99662.1|1864450_1865041_+|ADP-ribose-pyrophosphatase
MAELPNHDAALTETCLESEAIFEGSFLKLKRDTVRLPDGKKATREYVQHPGAVMVIPLFDDGRVLMESQYRYPIGKVMAEFPAGKLDPDEGALACAIRELREETGYTAREYVFLARIHPIISYSTEFIDLYLARGLTAGERKLDEGEFLETFTATQADLQEWVRTGQITDVKTIIGTMWLDKVASGTWPLGPVLTP
>CP029824.1|AWU99661.1|1864117_1864414_+|DUF2818-domain-containing-protein
MSAAGWFIVLLALVCANLPFLNQRLFAVVPFGATKKSAWVRIGELIVLYFIVGALGFWLESRAGNRFEQGWQFYAITFSLFIVFAFPGFTFQYLVKRR
>CP029824.1|AWU99660.1|1862648_1864118_+|NADH-quinone-oxidoreductase-subunit-NuoN
MQNAPMNVLLPDALVMAAIVVAWLNDTFTGASGRRLTYLIAVVSSVVAGVWFAVQALDPQQYYFFSKMVVVDSFASTMKAVVSFGFAVSLVYSRKYLEDRDMFRGDVFLLGMFSLLGQLVMVSGNNFLTLYLGLELMSLSLYAVIALRRDAPQSSEAAMKYYVLGALASGFVLYGISMLYGATGSLELGEVYKAVGGNTDAAVLMFGVVFIVAGIAFKLGAVPFHMWVPDVYQGAPTAMTLFVGGGPKVAAFAWGLRFLVMGLLPLAQNWQTALVILAALSLIVGNITGIVQRNIKRMLAYSAISNMGFVLLGLLAGIVKGDAAAPANAYSSAMFYAIVYLITTLGSFGVVMLLARRDFEAETIDDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYAKLAVLEATVNAGLTWLAVLAVITSLFGAFYYLRIVKLMYFDAPQDSTPISGDICKRTILVLNGLAVVVLGLIPSPLLTACLQAIRHTLPL
>CP029824.1|AWU99659.1|1861133_1862624_+|NADH-quinone-oxidoreductase-subunit-M
MHAFPILSTAIWLPIVFGLLVLAVGNDKNPGPARWLALIGSLLGLAVTIPLITGFDASTAALQFVEQSTWIERFNISYHLGVDGISMWFVVLTALITVIVVIAGWEVITEHVSQYLAAFLILSGIMVGVFSAADGLLFYVFFEATLIPMYIIIGVWGGPNRVYAAFKFFLYTLAGSLLMLVALIYLYTETHSFDLATWQNAKIAMTPQILLFIAFFLAFAVKVPMWPVHTWLPDAHVEAPTGGSVVLAAIMLKLGAYGFLRFSLPITPDASHFLAPVVITLSLIAVIYIGLVAMVQADMKKLVAYSSIAHMGFVTLGFFIFNQLGVEGAIIQMISHGFVSGAMFLCIGVLYDRVHSRQIADYGGVVNVMPKFAAFAMLFSMANCGLPGTSGFVGEFMVILAAVQYNFWIAFGAAFTLILGAAYTLWMYKRVYFGAVANDHVAKLKDIGRREFLMLAVLAAFTMLMGLYPKPFTDVMHVSVENLLSHVAQSKLPLAQ
>CP029824.1|AWU99658.1|1859060_1861115_+|NADH-quinone-oxidoreductase-subunit-L
MSTTLNENLLLAIPLAPLAGSLIAGLFGNAVGRKGAHRITILGVMIAFLLSAKVFVDVMGGASFNATIYEWMRVGSLKLEVGFLVDSMTAMMMVVVTFVSLMVHIYTIGYMSEEDGYQRFFSYISLFTFSMLMLVMSNNFLQLFFGWEAVGLVSYLLIGFYFTRESAIYANMKAFLVNRVGDFGFLLGIGLLLAFAGSMNYGEVFAKRAELASLHFPGTDWGLLTVACICLFIGAMGKSAQFPLHVWLPDSMEGPTPISALIHAATMVTAGIFMVSRMSPLFELSDTALSFVTVIGAITALFMGFLGIIQNDIKRVVAYSTLSQLGYMTVALGVSAYPVALFHLMTHAFFKALLFLGAGSVIIGMHHDQDIRNMGGLRKYMPITWITSLIGSLALIGTPFFSGFYSKDSIIEAVKESHLAGSGFAYFAVVASVFVTALYSFRMYFLVFHGEERFRNPKHPESPMGMAAAHGHDDHGHGHGHDDHAHEPHETPWVVWLPLVLLAIPSVIVGAIAIGPMLYGSFFEHGVAFDKVIFIGENHPGLEELGKEFHGWAAMGLHSLTTLPLWLAIAGVVVAWFLYLKRPELPAVIRRAFGPIYTLLDNKYYMDKINEVVFAKGSVAIGRGLWKEGDVVVIDGLVNGSARFIGWFAGVIRFLQSGYIYHYAFAMIIGMLGLLTLFVTLGGK
>CP029824.1|AWU99657.1|1858737_1859043_+|NADH-quinone-oxidoreductase-subunit-NuoK
MLTLAHYLVLGAILFAIAIVGIFLNRRNIIIILMAIELMLLAVNTNFVAFSHYLGDVHGQIFVFFVLTVAAAEAAIGLAILVTLFRKLDTINVEDLDQLKG
>CP029824.1|AWU99656.1|1858069_1858720_+|NADH-quinone-oxidoreductase-subunit-J
MEFTTVLFYIFALLLVVSGLKVITSRNPVASALFLVLAFFNAAAIWMLLEAEFLAILLVLVYVGAVMVLFLFVVMMLDINIDYLRRDFKRFVPMATVVGAIIVIETALILWRGYGDTHTVHAMATGEMANWSNTRLIGKVIYTDYIFAFEIAGLVLLVAIIAAIGLTERKGKDSKRQRVSDQVKVRRNDRVRLVKMEADKPEPETAQSEAGTSTNG
>CP029824.1|AWU99655.1|1857477_1857966_+|NADH-quinone-oxidoreductase-subunit-I
MTAIQHFFKTFFLTELLKGLALTGRYTFKRKFTVQFPEEKTPISPRFRGLHALRRYENGEERCIACKLCEAVCPALAITIESETRADNTRRTTRYDIDLTKCIFCGFCEESCPVDSIVETQILEYHGEKRGDLYFTKEMLLAVGDRYEKDIAAAKAADAPYR
>CP029824.1|AWU99654.1|1856397_1857465_+|NADH-quinone-oxidoreductase-subunit-NuoH
MSLFDTINAGGAQLLGFAWPTVWAIVRILVVSVVILLCVAYLILWERKLIGWMHVRLGPNRVGPGGLLQPIADVLKLLLKEVIQPSAASRWLYLIAPVMTVVPAFAVWAVIPFQAKAVLANINAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVLVLMTAGSLNMSEIVNSQQHGFFAGHGVNFLSWNWLPLLPAFVVYFISGIAETNRHPFDVVEGESEIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLKVFALLSVFIWVRATFPRYRYDQIMRLGWKVFLPVTVIWVVVVGFWMMSPLNIWVK
>CP029824.1|AWU99664.1|1865801_1866998_+|pimeloyl-CoA-dehydrogenase-large-subunit
MDLDYSPADDAFRVDVRTWLEANLPHALRAKVLDHKRLDREDFASWHRILGQRGWSAPAWPAEYGGPGWNATQRHIWDEECARIGAPTVLPFGVSMVAPVLMKYGSEAQKRHYLPRILDGSDWWCQGYSEPGSGSDLASLRTRAERQGDHYVVNGQKTWTTLGQYADMMFCLVRTDPAAKKQEGISFLLIDMKTPGITVRPIITLDEDHEVNEVFFEDVKVPVENLVGDENRGWTYAKYLLGHERTGIARVGASKRELAFLKRVASNQRKNGKPLLADPVFAAKVAALEVELMALEVTVLRVVSRETSGKGPGPEASMLKIKGTEVQQALTELMFDAIGPLAAPFDVPFLNGEREHSIAGDDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL
>CP029824.1|AWU99665.1|1867023_1868157_+|pimeloyl-CoA-dehydrogenase-small-subunit
MDFSFTDEQQQFADALRRYLGEQYGFDARQAIVRSDAGVSDTQWSAFAELGLTALPVPDAQGGFGGGPVDMLVAMQELGRALVIEPYWATAVGIEALRIAGSGAGDDAALLEAVAQGQKRLAVAFHEPHARYDLFELDTRAREQGGTHRLTGTKSVVQHGAQAHAWIVPARVDGGGIGLFVVERDAANAMVVDYRTIDGQRAATIEFNETPARLLTGGARDAAALEQIADYATFLLCAEAVGALDELNRATVEYTKTREQFGVPIARFQALQHRMVDMLIHAEQARSLTYLAAVRYAGGDADARRKAVSAAKARVGAAARFVGQQAVQLHGGMGVTNEVAAAHLFKRLSIIETTLGDTDHHLARIAALPDFAQADAA
>CP029824.1|AWV01276.1|1868195_1868657_+|dehydratase
MGISYEDLVVGSTIEVGSYTFEPDDIKAFAQRYDPQPFHLDEEAAKASPFGGLVASGWHTCSVFMSLLIKKLGPDSTSMGSPGIDSIRWLKPVRAGDTITMHQKIHDKRVSESKPDRGIVSTEWIGINGSGETVITVHSKVIFGLRDPRGTNA
>CP029824.1|AWU99666.1|1868653_1869130_+|MaoC-family-dehydratase
MTDVTLPLIASAQALQARVGAEPLASGWIAIDQRRVDGFADATGDHQWIHVDPERARRESPFGGPIAHGFLTLSLIPALMTDAMRFEQKMGVNYGLNRVRFLKPVPVGARVRALFAVKETAEVARGGVQVTWSVSIQAERPDAPLLVCAAEFITQHYF
>CP029824.1|AWU99667.1|1869177_1869870_-|glutathione-S-transferase-family-protein
MIDVYSWATPNGHKVHIMLEETGLAYRALPVDIGAGDQFKPEFLKISPNNKIPAIVDPDGPGGKPISLFESGAILIYLAEKTGKFLPTDPAARYATLEWLMFQMGGIGPMLGQAHHFRLYAPEKIEYAVNRYTNEAKRLYNVMEKRLGESEYLAGDAYTIADIATFPWTRSWQNQGIVLDEFPNVKRWHEAIAARPAVQRGVAVLASMRKALQDDKAREVLFGATQYAKH
>CP029824.1|AWU99668.1|1870127_1870919_-|enoyl-CoA-hydratase
MSAELLASRPPESDSTLVLTLSNPGARNALHPDMYAAGVEALATAERDPGIRAVVLTGADRFFCAGGNLNRLLDNRSKDPSYQADSIDQLGAWVTAIRESTKPVIAAVEGAAAGAGFSLALACDLIVAAHDAKFVMSYARVGLTPDGGGSWFLARALPRAIAAEILFEGKPVAAERLHALGVVNRLAAPGAALNDALAWADALAGISPNALSRVKSLLDVATTQPLEPHLGTERDHFVASLHHADGLEGITAFLEKRQPRYKR
>CP029824.1|AWU99669.1|1871120_1871777_+|glutathione-S-transferase
MLQLCGIPLSNYYNKVKFVLLEHDIPFEESVCSLPITDPAQLADSPLGKIPFLKTEEGALFESQVIIEYLAARYPEKAIFPAGPFAAAKVRELVETLELYLEWMAREVYTEAFFGGKVSDGMKAHVEKRLPRAIDAFKQMTQFSPYVLGESFSLADIAASIHLPVIGMATKAVFGRDFLLDAGIDWKAHAKKVGERAAAQRVAAERKAYVDATGGARS
>CP029824.1|AWU99670.1|1871821_1872994_-|methionine-aminotransferase
MNAPSDMPTTPVFPSRLPNVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVATAMRNGHNQYPPMAGVAPLRDAIADKIAHVYGRRYDPATEITVTAGATQALLTAILCAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDRLAAALTPKTRMILINTPHNPTGTVWREADMRKLEEIVRGTNVLILSDEVYEHMVYDGARHESVARYPELAARSFIVSSFGKTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLTLAGFYQKKRDFFRAGLERTRFKLLPCTGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFYHEPHESGVVRFCFAKQESTLASALERLARL
>CP029824.1|AWU99671.1|1873027_1873525_-|putative-toxin-antitoxin-system-toxin-component,-PIN-family
MTSSLAPHVAHRVVLDSNVWIDILVFDDPATRPIRAALERGALAAVIDGRCLTELEYVLDYPQFQARAIDKAAALATVARLASLVEPPPVDADAPPLPKCKDRDDQKFLELARAAQAEWLVSKDRALLKLAKRTARDFGFRIAQPAPFAEACALDAAAATPATPA
>CP029824.1|AWU99672.1|1873581_1874364_+|peroxide-stress-protein-YaaA
MIIVLSPAKSLDYDTPAHVQSYTKPAFVDDASELIDGLRKLSPQDIATLMDISDPLARLNFQRYADWSPIFTPANAKQAVLAFNGDVYEGFDAKSLSSADLDYAQQHVRVLSGLYGLLRPLDLLQPYRLEMGTRFANARGKDLYAFWGDRITRALNEQLETRRGAARVLVNCASTEYFKSVKPKLLAAPVITPVFEDWKGGRYKIISFHAKRARGLMARFIVENRIAEPKALKEFATEGYAFDVAASNDSTYVYRRRVGE

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Crispr_ID: CP029824_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029824_7

2103155-2103257

Orphan

Consensus_repeat	Method
CGCAGCGGCCGGCGCGCGATAGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029824_7

>merge|CP029824|7|2103155-2103257|CRISPRCasFinder
CGCAGCGGCCGGCGCGCGATAGGCGGTCGGCCGGCGCGGCATCGACCCACGGGCCCGTTTCGCGAAAGGCAGCCGGAAGCGGAGCGGCCGGCGCGCGATAGGC

>CP029824|7|6|2103155-2103257|CRISPRCasFinder
CGCAGCGGCCGGCGCGCGATAGGC	GGTCGGCCGGCGCGGCATCGACCCACGGGCCCGTTTCGCGAAAGGCAGCCGGAAG
CGGAGCGGCCGGCGCGCGATAGGC

Protein	Signature genes	Signature genes Name	Protein_function
CP029824.1\|AWU99848.1\|2111166_2112093_-\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|224666
CP029824.1\|AWU99846.1\|2108584_2110207_+\|microcin-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226641
CP029824.1\|AWU99842.1\|2103962_2104322_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235540
CP029824.1\|AWU99837.1\|2098260_2098593_+\|cytochrome-o-ubiquinol-oxidase-subunit-IV	unknown	unknown	gnl\|CDD\|131894
CP029824.1\|AWU99835.1\|2095645_2097652_+\|cytochrome-o-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|131890
CP029824.1\|AWU99833.1\|2092954_2094484_+\|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl\|CDD\|235622
CP029824.1\|AWU99845.1\|2107490_2108588_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226690
CP029824.1\|AWU99836.1\|2097651_2098260_+\|cytochrome-o-ubiquinol-oxidase-subunit-III	unknown	unknown	gnl\|CDD\|131889
CP029824.1\|AWU99849.1\|2112373_2113783_+\|glutamate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234953
CP029824.1\|AWU99847.1\|2110335_2111010_+\|peptidoglycan-endopeptidase	unknown	unknown	gnl\|CDD\|223862
CP029824.1\|AWU99844.1\|2106398_2107442_+\|microcin-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226642
CP029824.1\|AWV01296.1\|2099207_2099882_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|223816
CP029824.1\|AWU99841.1\|2102043_2102286_-\|DUF4148-domain-containing-protein	unknown	unknown	gnl\|CDD\|379321
CP029824.1\|AWU99834.1\|2094754_2095642_+\|ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|182518
CP029824.1\|AWU99838.1\|2098692_2098989_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379321
CP029824.1\|AWU99843.1\|2104462_2106346_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173862
CP029824.1\|AWU99850.1\|2115301_2115766_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP029824.1\|AWU99840.1\|2101304_2101970_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|223816
CP029824.1\|AWU99851.1\|2115785_2116664_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380379
CP029824.1\|AWU99839.1\|2099893_2101285_+\|histidine-kinase	unknown	unknown	gnl\|CDD\|223715

Protein	Function_ID	Function_description	E-value
CP029824.1\|AWU99848.1\|2111166_2112093_-\|patatin-like-phospholipase-family-protein	gnl\|CDD\|224666	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only].	1.88039e-63
CP029824.1\|AWU99846.1\|2108584_2110207_+\|microcin-ABC-transporter-ATP-binding-protein	gnl\|CDD\|226641	COG4172, COG4172, ABC-type uncharacterized transport system, duplicated ATPase component [General function prediction only].	0
CP029824.1\|AWU99842.1\|2103962_2104322_+\|hypothetical-protein	gnl\|CDD\|235540	PRK05641, PRK05641, putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated.	0.000342551
CP029824.1\|AWU99837.1\|2098260_2098593_+\|cytochrome-o-ubiquinol-oxidase-subunit-IV	gnl\|CDD\|131894	TIGR02847, Cytochrome_bo3_ubiquinol_oxidase_subunit_4, cytochrome o ubiquinol oxidase subunit IV. Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant. [Energy metabolism, Electron transport].	2.18581e-37
CP029824.1\|AWU99835.1\|2095645_2097652_+\|cytochrome-o-ubiquinol-oxidase-subunit-I	gnl\|CDD\|131890	TIGR02843, Cytochrome_bo3_ubiquinol_oxidase_subunit_1, cytochrome o ubiquinol oxidase, subunit I. Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant. [Energy metabolism, Electron transport].	0
CP029824.1\|AWU99833.1\|2092954_2094484_+\|NADH-quinone-oxidoreductase-subunit-M	gnl\|CDD\|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	0
CP029824.1\|AWU99845.1\|2107490_2108588_+\|ABC-transporter-permease	gnl\|CDD\|226690	COG4239, COG4239, ABC-type uncharacterized transport system, permease component [General function prediction only].	4.64998e-167
CP029824.1\|AWU99836.1\|2097651_2098260_+\|cytochrome-o-ubiquinol-oxidase-subunit-III	gnl\|CDD\|131889	TIGR02842, Cytochrome_bo3_ubiquinol_oxidase_subunit_3, cytochrome o ubiquinol oxidase, subunit III. Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant. [Energy metabolism, Electron transport].	7.25472e-97
CP029824.1\|AWU99849.1\|2112373_2113783_+\|glutamate--tRNA-ligase	gnl\|CDD\|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
CP029824.1\|AWU99847.1\|2110335_2111010_+\|peptidoglycan-endopeptidase	gnl\|CDD\|223862	COG0791, Spr, Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane].	1.00077e-41
CP029824.1\|AWU99844.1\|2106398_2107442_+\|microcin-ABC-transporter-permease	gnl\|CDD\|226642	COG4174, COG4174, ABC-type uncharacterized transport system, permease component [General function prediction only].	0
CP029824.1\|AWV01296.1\|2099207_2099882_+\|DNA-binding-response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.14634e-79
CP029824.1\|AWU99841.1\|2102043_2102286_-\|DUF4148-domain-containing-protein	gnl\|CDD\|379321	pfam13663, DUF4148, Domain of unknown function (DUF4148).	0.00123937
CP029824.1\|AWU99834.1\|2094754_2095642_+\|ubiquinol-oxidase-subunit-II	gnl\|CDD\|182518	PRK10525, PRK10525, cytochrome o ubiquinol oxidase subunit II; Provisional.	4.48379e-153
CP029824.1\|AWU99838.1\|2098692_2098989_-\|hypothetical-protein	gnl\|CDD\|379321	pfam13663, DUF4148, Domain of unknown function (DUF4148).	8.76145e-09
CP029824.1\|AWU99843.1\|2104462_2106346_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173862	cd08497, PBP2_NikA_DppA_OppA_like_14, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
CP029824.1\|AWU99850.1\|2115301_2115766_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.41196e-10
CP029824.1\|AWU99840.1\|2101304_2101970_+\|DNA-binding-response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.88195e-24
CP029824.1\|AWU99851.1\|2115785_2116664_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|380379	cd06124, cupin_NimR-like_N, AraC/XylS family transcriptional regulators similar to NimR, N-terminal cupin domain. This family contains mostly bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included in this family is Escherichia coli HTH-type transcriptional regulator NimR (also called YeaM) that negatively regulates expression of the nimT operon and its own expression. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	3.80325e-32
CP029824.1\|AWU99839.1\|2099893_2101285_+\|histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	9.83217e-40

>CP029824.1|AWU99841.1|2102043_2102286_-|DUF4148-domain-containing-protein
MKTSMFAILLSAFCVALPGRAGATQPTAATAPQTPAPSSPHAAWNTPQAMPLTRAQVYRELVHAERDGQLAQLDRELYSH
>CP029824.1|AWU99840.1|2101304_2101970_+|DNA-binding-response-regulator
MRILLIAPPHPEAARLDKAFRESTHGVERVGEWRDGCFAATQDRFDAIVIIAPDAADGPAVLDALPRLAGSAAGATIAAIVAGATPTQRARMLQAGCDVCLAHPCSFVELHERLRALWRRAGVIEMREPVRLDTATRALEEGGRRLALSAREFRLVECLLRASGRPVGRDAVLRYAWGDADIEPETVNALVVRLRRKLAAHAFSARIETVARFGFRFDSGA
>CP029824.1|AWU99839.1|2099893_2101285_+|histidine-kinase
MDAARAANFTRRWHTTTFRWLCAYAAIFSVSLLLLAGVISVAATHTMARDTDEVLAWQLIYFDSIPDAQLPLAIHRRLEHEHLHTSFYGLFDAAGRRVAGDIATLPALRTDRNGRTLNRTLVPLDGQPARITRAMAVRRDNGMTLVVARDLSHFIQIRDVAIRGLVIGGVMILIAGIAGGSMLGMRQMRRVAAIRRATRQIAEGDLGKRLPVGRYDELDLLAHLVNHMLDEVERLMGEVRHTCDGIAHDLRTPLARVHTMLARLAEQPFCADDPASAALLASARDETDRLLERFRAMLRISEIGTLSRRGGFAAVDVAALLRDVCELYEPLAEAVDVSFELDAAPVDGIHGDRALLFEAFSNLADNAIKFTPPGGRVRAVLRSTPGGPLVRFEDTGPGIPPGERDAVLERFYRGEHTRHVKGSGLGLSIVSAVMHVHGFALRIGDAQPAGAAITVECWPRSLA
>CP029824.1|AWV01296.1|2099207_2099882_+|DNA-binding-response-regulator
MRVLTVEDDAVTANEIVGELTARGFEVDWIDNGREGMMRAMSASYDAITLDRMLPGADGLAILTAMRTVGIDTPVLMLSALGDVDERIRGLRAGGDDYLTKPFDSGELSARIEVLLRRRQASGVPQQTLLKVGALELDLISRCARRGADEIPLLPTEFRVLEFMMRNAGQTITRTMLFEAVWGYHFDPGTNLIDVHMGRLRKKIDPPGANPMIQTVRGSGYMLA
>CP029824.1|AWU99838.1|2098692_2098989_-|hypothetical-protein
MKLSTTVACMLFACASTAAFAAPHLTPQECNAYPFVHTGHEVTHADLVRELTELEQAGYDPAHASPYYPDDLDAAKHRLAAEYRTDCTHALTADAGKH
>CP029824.1|AWU99837.1|2098260_2098593_+|cytochrome-o-ubiquinol-oxidase-subunit-IV
MAHSHSSQLEEGHGSVGGYVAGFILSVLLTAASFGLVMGGVLSPHASLIALAVLAFVQIVVHLVYFLHMNGSSGQRWNVMAFSYTVLTAAILIVGTLWVMHNVSMNMMSR
>CP029824.1|AWU99836.1|2097651_2098260_+|cytochrome-o-ubiquinol-oxidase-subunit-III
MLQKTLSATLLEHDDHPPSHSVFGFWLYLMTDCVIFAALFATFAVLGQQYAGGPTAKDLFDIPGVAVETAALLLSSITYGFAMLAAYKQRRGALLAWLAVTFVLGAAFLAMELREFSHLIAEGAGPQRSAFLSAFFTLVGTHGLHVTAGLLWMLVLAGQIVFRGGDLTDRDLRRLTCLSLFWHFLDIVWICVFSFVYLASVI
>CP029824.1|AWU99835.1|2095645_2097652_+|cytochrome-o-ubiquinol-oxidase-subunit-I
MFGKLTLSAIPFDQPIIMVAGAFMGLAVLGILAALTITGRWKWLWTEWLTTVDHKKLGVMYIIVALIMLLRGFADAIMMRMQLALAYNAPGYLPPHHYDQIFTAHGVIMIFFMAMVFMVGLMNLIVPLQIGARDVAFPFINSLSFWMTAVSAILINISLVIGEFAQTGWLAYPPLSELQFSPGVGVDYYLWALQISGVGTLLTGVNFFVTIIKMRAPGMTLLKMPVFTWTALCTNVLIMASFPILTATLALLGLDRYLGMHFFTNEAGGNAMLYLNLIWAWGHPEVYILILPAFGIFSEVIATFAKKPLFGYKTMVYATCAIMVLSFLVWLHHFFTMGSGANVNAFFGIMTMIIAIPTGVKVFNWLFTMYRGRIEFTTPVLWTIGFMVTFTLGGMTGVMMAIPGADFVLHNSLFLIAHFHNVIIGGVLFGYLAGFNYWFPKAFGFKLNEKLGKAAFWFWQVGFYVAFVPLYVLGFMGMTRRLNHYDNPAWHPWLLVAAFGAVLIAIGIACQLLQLVVSIRNRNLPEYRDTTGDPWGGRTLEWATSSPPADYNFAVIPQVRTLDAYADLKARGEGRPNPASIRDIHMPSNTCAGLVVAIFSLVLGFALVWHIWWLAITGLVGIVATLVIYSSRDNDGYYIPASTVRKIEDKQPTKRVPARVDDVELEAN
>CP029824.1|AWU99834.1|2094754_2095642_+|ubiquinol-oxidase-subunit-II
MKTRASRGWSALMSIGAALSLSGCNLDVLNPKGSVGSAEKALIATSTWAMLIVVVPVILLTLWFAWRYRASNRNATYAPNWSHSTAIEVVIWTVPTLIILFLGVLTWKTTHELDPYKPLESSVKPIDVEVVALDWKWLFIYPELGIASVNQLAIPVGTPVNFRITSDSVMNSFFIPQLGGQVYAMAGMQTRLHLIADEPGNYAGTSANFSGRGFSDMKFRTLAEPREQFDAWVQKVKASPDRLDATVYGTVAQPSEKAPVRYFSSVDPRLFHNIIAKYNDGHVLDLKDAACGTKG
>CP029824.1|AWU99833.1|2092954_2094484_+|NADH-quinone-oxidoreductase-subunit-M
MHDFPFLSLAIWVPILFGACLLRAGSDRHPRRTRLIALAGALAGLVAVVPLVAGFDAHSAAMQFVESRNWLAAFNSGWRVGIDGASLWLVVLTAFTTLMVVVASWEAVTVRVAQYYASFLILSGLMVGVFAAQDGLLFFIFFEATLIPLYLLIGTWGRERRVYAAVKFFFISFAGSLLLLMAMLYLYAQSHTFDLAVWRTLQLGFAPQLLVFLGFFVAFAVKVPMWPVHTWLSDVYTDGPTGAALMLAMLKLGGYGFLRFALPITPDASHFFAPAVIALSLFAIVYASLIALAQTDLGKLLAYSTVAHMGIVTLGLFLFNRIGVEGAIVQLVSYGFVAGAMLLCVNVLVDRTKQREIAAYGGVAGVMPRFATFTLLFAMANVGLPGTSGFVGEFMVIMGAIRFNFWIGAIAALTLILSASYTLWMLKRVVFGKVSSQRIAKLADLNRREIAMFASLALIVLAIGIDPKPFTDAIDPTVGKLIDEASRSKVPAADGPVHAQPAYMASTHG
>CP029824.1|AWU99842.1|2103962_2104322_+|hypothetical-protein
MKTLRVASLLTAMTALLVSGAAMAGVNVGINVGVPAPVYVAPAPVYAPPPPVIYQPAPVYAPAPVYAPAPAIVIGWHGDRYWDGRRYWGRDEWYRHHGRGWGGDRDRGHWDHGRHNGWR
>CP029824.1|AWU99843.1|2104462_2106346_+|ABC-transporter-substrate-binding-protein
MTKGSPRAAIARVRFGALRAARAAGRGAAVFALQAALAATAAHAAYAIAQYGEPKYPPGFKHFDYVNPAAPKGGTLVLANPNRLTSFDKFNPFTMRGNSAPGIDMLFESLATGSSDEPASAYGLLADDIDIAPDRRSVTFHLNPRARFSNGDAVTADDVKFSFDTLKSRLAAPQFGAYFAEIAKAVVVDRATVRFEFRSANRELPLIAGGVPVFSRKWGLRADGSRIPFDQLAFEQPIGSGPYLIERYDNGRTITYRRNPAYWGADLPVRVGTHNFERIVYKLYGDGVTRLEAFKAGEYDVLVEYIARNWARRDVGKRFDSGELVKREFRQHNGAGMQGFFMNLRRPLFRDARVRQALDLAFDFEWLNRQLFYSAYTRLDSYFADTDLQATGTPGAGELKLLEPLRAQLDPAVFGPMVAQPDTNPPGSLRANLLKARALLAQAGWTYRDGALRNAKGEPFTFEILDDAGGAMEGVVTAYRRNLAKLGIDARFRTADYALLQKRLDAFDYDMTTVRLPGVQVPGAEQFSRYGSKFADVPGSDNIIGLKSPAVDALLHALGTAQTRDELLDATHALDRVLMHGYYAVPQWYSTTHRIAYKRTLAYPQTLPLYYSAEGWVVSTWWAKPDH
>CP029824.1|AWU99844.1|2106398_2107442_+|microcin-ABC-transporter-permease
MWSYILKRLLLMIPTLVGVLTLTFAVTQFVPGGPVEQTVQELRKGATEQGAVPFGMRAHTGVDAQQLAQIKALYGFDKPPLERYWLMLKRFARFDLGDSYFRHQSVWSLIVQKLPVSISIGLWTFFLTYLISVPLGIAKAVRNGSPFDVATSLVVLVGYAIPGFVLGVLLLVLFGGGSFWQLFPLRGLTSDNFAELSLVGKVLDYLWHIALPITASVVGSFAVVTMLTKNAFLDQIRRQYVLTARAKGLSERSVLWKHVFRNAMLPLIVGFPAAFIGAFFTGSLLIETLFSLDGLGLLSYESVVRRDYPVVLGTLYLFTLIGLATKLISDLCYVWVDPRIQFDNLER
>CP029824.1|AWU99845.1|2107490_2108588_+|ABC-transporter-permease
MNRAVVSSRIDVARAHVSPSPARRVWQRFRQQRIGYWSFVIFVVAFAASLAAPLWSNDKPLVVRYDGQYYFPLFHAYPETTFGGDFPAPADYLDPYVRKRLEAPGNFVVYPPNRYYYDTLNYFSNVPNPAPPSRQNWLGTDAQGRDLLARLVYGFRVSVEFGLILTVIGTLLGIAAGAVQGFFGGRIDIVGQRLIEIWSSLPELYLLIIFASIFEPSFLLLIVLLSLFGWIGLADYVRAEFLRNRTQDYVRAARAMGLTNWQIIWRHVLPNSLTPVITFLPFRMSGAILALTSLDFLGLGVPPPTPSLGELLAQGKGNLDAWWISLSTFGVLVATLLLLTFMGDALRNALDTRIADSIRAAGGQR
>CP029824.1|AWU99846.1|2108584_2110207_+|microcin-ABC-transporter-ATP-binding-protein
MSETVVSKHDEPLLSLERLHVRFGDTVAVDDVTLAIGRGERVALVGESGSGKSVTALSILRLLYDADVSGAIRFAGQDLSTKSEREMRGLRGSDIAMIFQEPMTALNPLYTIGAQIGETIVLHDGVSAVEARKRAIALLARTGIAEPDKRVDSYPHQLSGGQRQRAMIAMALACRPRLLLADEPTTALDVTIRAQIVELLLELQREEAEKRGMAILLITHDLNLVRHFADRVAVMEHGRLVESGPVERIFAEPEHPYTQRLLNSRPQRAVAPVMPIAPVVLDARHVSVQFARKRPGFAGWFGTVPVTAVADVSVSVRQGETLGIVGESGSGKSTLAMALLGLQKTAGGEIEFQGRALSTYRGRERTALRSNMQVVFQDPFSSLSPRHTIERIVGEGLELHRPEMTPDARRAKSLAVLREVGLDRTVLHRYPHEFSGGQRQRIAIARALVLEPRILILDEPTSALDVSIQQQVLKLLANLQQKYNLGYVFISHDLEVIGAMAHRVAVMQDGAVVESGDVADIFTKPSHPYTQKLLKAVWKA
>CP029824.1|AWU99847.1|2110335_2111010_+|peptidoglycan-endopeptidase
MQHRSLTQACARTIAGLFIGALFAAVPGAFADEVSSFNQNVTNSTQIGSGSSLQQTSAQPSGGGAKSFLAGMAGKAGDVVVGALNMIGVRYRWGGNSPDSGLDCSGFVRYVFQDTLGMSLPRRAEEMSRVGEKVSMSNLKPGDLVFFNTMRRTFSHVGIYIGDNKFVHSPSTGSTVRVDDLDSGYWEKRFTGARRLESEFPMKAEDLRQRVRATIGDDSASGNN
>CP029824.1|AWU99848.1|2111166_2112093_-|patatin-like-phospholipase-family-protein
MSSPRLSRRHFTIACASASLAACTSFGGKSRPDNASNPAQPNEKPVKIGIALGGGAARGFSHIGVLKALEARGIPIEIVAGTSAGSVVGALYASGMSALQINKIALDMDQAAISDWALPFRSRGLLQGVALQNFLNKTLNNRSIEKMAKPLGIVATDLQSGQPILFQQGNTGLAVRASCSVPSVFEPVKIGNREYVDGGLVSPVPASYARKMGASFVIAVDISARPDGAATNNPIEMLLQTFTIMGQTIKTYELDKYADVVVRPNLAAMGGSDFNQRNAAILAGEEAVARIMPELQRKLAAARGVAAA
>CP029824.1|AWU99849.1|2112373_2113783_+|glutamate--tRNA-ligase
MTRPVRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDVERSSQEAVDAILEGMQWLGLDFDEGPIYQMQRMDRYREVLAQMLEKGLAYPCYMSAEELDALRERQREAGLKPRYDGTWRPEPGKVLPEPPAGVKPVLRFRNPLTGTVVWDDAVKGRVEISNEELDDLVIARPDGTPIYNFCVVVDDMDMGITHVIRGDDHVNNTPRQINILNALGGEAPVYAHLPTVLNEQGEKMSKRHGAMSVMAYRDAGFLPEAVVNYLARLGWSHGDAEIFSREQFVEWFDLEHLGKSPAQYDHSKLSWLNAHYIKEADNARLAALAKPFLDALGIDDAAIATGPALDAVVGLMKDRATTVKEIAEGAGMFYRVPAPEADALAQHVTDAVRPALADLVVALKAADWTKEAVSAALKATLGTHKLKMPQLAMPVRLLVAGTTHTPSIDAVLVLFGRDVVVSRIEAALA
>CP029824.1|AWU99850.1|2115301_2115766_+|GNAT-family-N-acetyltransferase
MLDPTDLRLLYQLRPAEPDDFPFAEALTHGNMGGYYKRHGLVWRSDLFYASWRESENFILEADGERIGVLRVTEEGDSLHIRDVQIAAGHRGQGAGTYMLDMSHRWARARGLHELQLRVFVDNPAARLYLRMGYQVAGPRLAQLGSIRHMVRPV
>CP029824.1|AWU99851.1|2115785_2116664_-|AraC-family-transcriptional-regulator
MNPPVQADASNPYDVIDIPPEFAPTTVHPMRVRARRVDAGHRIPLHTHAWAQLAYASRGVLRVATTGTTWMVPPSRAIWVPPHVTHEVVIVEEAYLRTLYIDESIVPDGLDACRVVEVTGLLRELIVALDARNLGTARERLLCGLVLDELSHAEPLPLAVPMPDEKRLRMLCESVLAQPAHAESLEHWASEVGASTRTISRLFKQELGVSFSQWRQQALLARAIPLLNQGRPLSHIARELGYQSQSAFSAMFRRAFGESPRAFMLRGYEHRGAEGRIADDESPDDDAIDAGR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP029824_6	6.1\|1865710\|25\|CP029824\|CRISPRCasFinder	1865710-1865734	25	NC_018696	Paraburkholderia phenoliruptrix BR3459a plasmid pSYMBR3459, complete sequence	676458-676482	3	0.88
CP029824_1	1.1\|178281\|25\|CP029824\|CRISPRCasFinder	178281-178305	25	NZ_AP018751	Klebsiella pneumoniae strain KP64 plasmid pKP6401, complete sequence	10663-10687	4	0.84
CP029824_6	6.1\|1865710\|25\|CP029824\|CRISPRCasFinder	1865710-1865734	25	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	646885-646909	4	0.84

1. spacer 6.1|1865710|25|CP029824|CRISPRCasFinder matches to NC_018696 (Paraburkholderia phenoliruptrix BR3459a plasmid pSYMBR3459, complete sequence) position: , mismatch: 3, identity: 0.88

caagtgctaaagcgctaactccggt	CRISPR spacer
taagcgctaaagcgctaactcccgt	Protospacer
.***.***************** **

2. spacer 1.1|178281|25|CP029824|CRISPRCasFinder matches to NZ_AP018751 (Klebsiella pneumoniae strain KP64 plasmid pKP6401, complete sequence) position: , mismatch: 4, identity: 0.84

gcttactctcatcccatgcttcgcg	CRISPR spacer
ccttaatctcatcacatgcttcgct	Protospacer
 **** ******* **********

3. spacer 6.1|1865710|25|CP029824|CRISPRCasFinder matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 4, identity: 0.84

caagtgctaaagcgctaactccggt	CRISPR spacer
taagtgctgaagcgctaactcccat	Protospacer
.*******.************* .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

51156 : 60216

unidentified_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWU98163.1\|51156_52692_+	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	8.0e-23	31.0
AWU98164.1\|52727_53270_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
AWU98165.1\|53266_53953_+	deoxynucleoside kinase	A0A0M3UL55	Enterococcus_phage	3.6e-07	28.8
AWU98166.1\|53998_54814_+	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	2.0e-36	33.3
AWU98167.1\|54929_56846_-	aminodeoxychorismate synthase component I	S4VT78	Pandoravirus	1.3e-54	36.4
AWU98168.1\|56859_57996_-	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	5.3e-24	39.5
AWU98169.1\|58007_58286_+	hypothetical protein	NA	NA	NA	NA
AWU98170.1\|58263_60216_-	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	4.1e-149	49.9

DBSCAN-SWA_2

322251 : 372941

Pseudomonas_phage(20.0%)

tRNA,transposase,plate,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWU98382.1\|322251_323550_+\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
AWU98383.1\|323631_324714_+	peptide chain release factor 1	A0A0S4KWG0	Pseudomonas_phage	6.7e-08	46.6
AWU98384.1\|324721_325564_+	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
AWU98385.1\|325631_325943_+	Grx4 family monothiol glutaredoxin	NA	NA	NA	NA
AWU98386.1\|325977_326574_+	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	NA	NA	NA	NA
AWU98387.1\|326784_327576_+	dioxygenase	NA	NA	NA	NA
AWU98388.1\|327685_329284_-	amino acid:proton symporter	NA	NA	NA	NA
AWU98389.1\|329266_329488_+	hypothetical protein	NA	NA	NA	NA
AWU98390.1\|329704_329908_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	8.3e-21	71.6
AWU98391.1\|330002_331253_-	heat-shock protein	NA	NA	NA	NA
AWU98392.1\|331440_332046_-	nitroreductase	NA	NA	NA	NA
AWU98393.1\|332203_333487_-	MFS transporter	NA	NA	NA	NA
AWU98394.1\|333707_334328_+	TetR family transcriptional regulator	NA	NA	NA	NA
AWU98395.1\|334404_334977_+	DUF1415 domain-containing protein	NA	NA	NA	NA
AWV01161.1\|335026_335917_-	SAM-dependent methyltransferase	NA	NA	NA	NA
AWU98396.1\|336006_337140_-	methyltransferase	NA	NA	NA	NA
AWU98397.1\|337265_337598_-	hypothetical protein	NA	NA	NA	NA
AWU98398.1\|337766_338261_-	Water stress and hypersensitive response domain-containing protein	NA	NA	NA	NA
AWU98399.1\|338904_341073_+	peptidase M1	A0A0P0IY26	Acinetobacter_phage	6.3e-50	26.7
AWU98400.1\|341207_342128_-	LysR family transcriptional regulator	NA	NA	NA	NA
AWU98401.1\|342290_343268_+	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
AWU98402.1\|343292_343445_+	DUF1427 family protein	NA	NA	NA	NA
AWU98403.1\|343466_344495_-	magnesium transporter CorA	NA	NA	NA	NA
AWU98404.1\|344700_345681_-\|tail	phage tail protein	NA	NA	NA	NA
AWU98405.1\|345802_346648_+	M15 family peptidase	NA	NA	NA	NA
AWU98406.1\|346949_350894_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
AWU98407.1\|350890_351880_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
AWU98408.1\|351884_352844_+	cell envelope biogenesis protein OmpA	NA	NA	NA	NA
AWU98409.1\|352926_354048_-	type VI secretion system protein TssA	NA	NA	NA	NA
AWU98410.1\|354104_356774_-	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	3.8e-89	32.0
AWU98411.1\|356818_357919_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
AWU98412.1\|357882_359718_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
AWU98413.1\|359794_360280_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
AWU98414.1\|360342_360846_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
AWU98415.1\|360916_362407_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
AWU98416.1\|362422_362938_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
AWU98417.1\|362985_363633_-	hypothetical protein	NA	NA	NA	NA
AWU98418.1\|364007_364619_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
AWU98419.1\|364721_366068_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
AWU98420.1\|366064_366847_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
AWU98421.1\|366932_367256_-	hypothetical protein	NA	NA	NA	NA
AWU98422.1\|367681_367987_-	hypothetical protein	NA	NA	NA	NA
AWU98423.1\|369129_369420_-	hypothetical protein	NA	NA	NA	NA
AWU98424.1\|370148_370367_-	hypothetical protein	NA	NA	NA	NA
AWU98425.1\|370308_371109_+	cystine ABC transporter substrate-binding protein	NA	NA	NA	NA
AWU98426.1\|371168_371372_-	hypothetical protein	NA	NA	NA	NA
AWU98427.1\|371681_372941_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.1e-44	45.0

DBSCAN-SWA_3

2164155 : 2233379

uncultured_Caudovirales_phage(25.0%)

plate,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWU99890.1\|2164155_2165541_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
AWU99891.1\|2165603_2167913_+	outer membrane protein assembly factor BamA	NA	NA	NA	NA
AWU99892.1\|2167947_2168475_+	OmpH family outer membrane protein	NA	NA	NA	NA
AWU99893.1\|2168491_2169574_+	UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase	NA	NA	NA	NA
AWU99894.1\|2169703_2170171_+	beta-hydroxyacyl-ACP dehydratase	NA	NA	NA	NA
AWV01299.1\|2170224_2171013_+	acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase	NA	NA	NA	NA
AWU99895.1\|2171016_2172186_+	lipid-A-disaccharide synthase	NA	NA	NA	NA
AWU99896.1\|2172182_2172827_+	ribonuclease HII	D2TEQ2	Emiliania_huxleyi_virus	1.4e-29	42.9
AWU99897.1\|2172823_2173606_+	RNA methyltransferase	NA	NA	NA	NA
AWU99898.1\|2173707_2174523_-	kinase/pyrophosphorylase	NA	NA	NA	NA
AWU99899.1\|2174900_2177300_+	phosphoenolpyruvate synthase	A0A1V0SGR7	Hokovirus	4.9e-168	35.7
AWU99900.1\|2177553_2177988_+	NfeD family protein	NA	NA	NA	NA
AWU99901.1\|2178021_2178957_+	SPFH/Band 7/PHB domain protein	NA	NA	NA	NA
AWU99902.1\|2179197_2179644_-	SsrA-binding protein	W5RAM5	Staphylococcus_phage	3.4e-27	43.4
AWU99903.1\|2179742_2180180_+	type II toxin-antitoxin system RatA family toxin	NA	NA	NA	NA
AWU99904.1\|2180184_2180508_+	RnfH family protein	NA	NA	NA	NA
AWU99905.1\|2180569_2181553_-	EamA/RhaT family transporter	NA	NA	NA	NA
AWV01300.1\|2181731_2182418_-	glutamine cyclotransferase	NA	NA	NA	NA
AWU99906.1\|2182449_2183670_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AWU99907.1\|2183784_2184549_+	DUF899 domain-containing protein	NA	NA	NA	NA
AWU99908.1\|2184579_2185386_+	DUF2182 domain-containing protein	NA	NA	NA	NA
AWU99909.1\|2185663_2187124_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.0e-95	39.6
AWU99910.1\|2187130_2187730_+	hypothetical protein	NA	NA	NA	NA
AWU99911.1\|2187844_2189464_+	GMP synthase (glutamine-hydrolyzing)	A0A1V0SH76	Hokovirus	6.5e-15	27.3
AWU99912.1\|2190566_2191289_-	hypothetical protein	NA	NA	NA	NA
AWU99913.1\|2191776_2194458_+	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	1.9e-80	31.8
AWU99914.1\|2194497_2195040_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
AWU99915.1\|2195067_2196561_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
AWU99916.1\|2196652_2197138_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
AWU99917.1\|2197223_2197724_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
AWU99918.1\|2197755_2199102_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
AWU99919.1\|2199153_2200416_+	type VI secretion system protein TssL	NA	NA	NA	NA
AWU99920.1\|2200441_2204512_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
AWU99921.1\|2204530_2205796_+	type IV secretion protein DotU	NA	NA	NA	NA
AWV01301.1\|2205837_2206089_+	PAAR domain-containing protein	NA	NA	NA	NA
AWU99922.1\|2208864_2210097_+	hypothetical protein	NA	NA	NA	NA
AWU99923.1\|2210098_2210989_+	hypothetical protein	NA	NA	NA	NA
AWU99924.1\|2213750_2214731_+	hypothetical protein	NA	NA	NA	NA
AWU99925.1\|2214695_2215715_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	2.9e-45	35.6
AWU99926.1\|2216056_2216917_+	hypothetical protein	NA	NA	NA	NA
AWU99927.1\|2217179_2218142_+	hypothetical protein	NA	NA	NA	NA
AWU99928.1\|2218805_2221541_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	8.0e-34	25.5
AWU99929.1\|2221588_2226196_+	RHS family protein	A0A2H4JFP5	uncultured_Caudovirales_phage	4.5e-53	48.8
AWU99930.1\|2226195_2226579_+	DUF2750 domain-containing protein	NA	NA	NA	NA
AWU99931.1\|2226614_2227094_+	hypothetical protein	A0A2H4JHK7	uncultured_Caudovirales_phage	1.6e-17	66.1
AWU99932.1\|2227090_2227486_+	hypothetical protein	NA	NA	NA	NA
AWU99933.1\|2228702_2228954_+	hypothetical protein	NA	NA	NA	NA
AWU99934.1\|2228999_2230019_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	2.9e-45	35.6
AWU99935.1\|2230145_2231232_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.4e-44	37.2
AWU99936.1\|2231741_2232053_+	hypothetical protein	NA	NA	NA	NA
AWU99937.1\|2232104_2233379_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_4

3541139 : 3551579

Bacillus_virus(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV00972.1\|3541139_3542441_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	4.7e-93	50.4
AWV00973.1\|3542687_3542957_+	DUF2164 domain-containing protein	NA	NA	NA	NA
AWV00974.1\|3542996_3544307_-	recombination factor protein RarA	G3MBE0	Bacillus_virus	1.9e-81	40.2
AWV00975.1\|3544483_3545173_-	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
AWV00976.1\|3545219_3547529_-	DNA translocase FtsK	G1FGP1	Mycobacterium_phage	1.4e-84	50.0
AWV00977.1\|3547882_3548845_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.2e-61	43.3
AWV00978.1\|3548980_3549760_+	DNA mismatch repair protein MutS	A0A0P0IDT4	Acinetobacter_phage	3.8e-13	31.4
AWV00979.1\|3549746_3550370_+	trimeric intracellular cation channel family protein	NA	NA	NA	NA
AWV00980.1\|3550460_3551579_-	sugar ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.0e-24	35.3

DBSCAN-SWA_5

3632147 : 3639413

Escherichia_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV01057.1\|3632147_3633368_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.4e-14	27.0
AWV01058.1\|3633367_3634162_-	ABC transporter permease	NA	NA	NA	NA
AWV01059.1\|3634161_3635610_-	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	1.6e-52	28.4
AWV01060.1\|3636018_3636918_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	6.5e-25	35.8
AWV01061.1\|3636910_3637462_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	4.7e-50	53.0
AWV01062.1\|3637446_3638340_-	glucose-1-phosphate thymidylyltransferase	A0A291LA53	Escherichia_phage	4.9e-97	58.9
AWV01063.1\|3638351_3639413_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	4.1e-87	47.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP029826

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 27903

Tupanvirus(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04261.1\|1152_2421_-	hypothetical protein	NA	NA	NA	NA
AWV04262.1\|2372_3104_-	hypothetical protein	NA	NA	NA	NA
AWV04263.1\|2956_11344_-	hypothetical protein	D0R7J2	Paenibacillus_phage	4.1e-28	31.5
AWV04264.1\|11394_23904_-	hypothetical protein	A0A2K9KZV5	Tupanvirus	1.1e-56	31.8
AWV04265.1\|24037_25135_-	alpha/beta hydrolase	NA	NA	NA	NA
AWV04266.1\|25131_26073_-	chlorinating enzyme	NA	NA	NA	NA
AWV04267.1\|26073_27903_-	hypothetical protein	A0A2K9L3I8	Tupanvirus	2.2e-51	28.3

DBSCAN-SWA_2

44283 : 47388

Leptospira_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04282.1\|44283_47388_+	AcrB/AcrD/AcrF family protein	S5VTK5	Leptospira_phage	4.8e-59	22.2

DBSCAN-SWA_3

53774 : 58465

Synechococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04287.1\|53774_54647_-	NAD(P)-dependent oxidoreductase	A0A1D8KKD5	Synechococcus_phage	5.0e-06	27.9
AWV04288.1\|54790_55699_+	LysR family transcriptional regulator	NA	NA	NA	NA
AWV04289.1\|56383_57322_-	EamA family transporter	NA	NA	NA	NA
AWV04290.1\|57366_58465_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.0e-36	37.3

DBSCAN-SWA_4

84139 : 85468

Burkholderia_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04306.1\|84139_85468_-	alpha-ketoglutarate transporter	Q6JIH2	Burkholderia_virus	1.3e-42	30.8

DBSCAN-SWA_5

88817 : 89714

Lactobacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04310.1\|88817_89714_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	4.8e-12	26.1

DBSCAN-SWA_6

93656 : 101792

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04313.1\|93656_94607_+	SDR family NAD-dependent epimerase/dehydratase	A0A2K9KZK0	Tupanvirus	4.2e-83	47.9
AWV04314.1\|94805_96116_+	diaminobutyrate--2-oxoglutarate transaminase	A0A1V0SKB7	Klosneuvirus	5.8e-22	24.9
AWV05261.1\|96193_97165_+	TauD/TfdA family dioxygenase	NA	NA	NA	NA
AWV04315.1\|97376_101792_+	beta-ketoacyl synthase	D0R7J2	Paenibacillus_phage	1.3e-33	33.3

DBSCAN-SWA_7

105108 : 110898

Paenibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04317.1\|105108_110898_+	hypothetical protein	D0R7J2	Paenibacillus_phage	5.0e-25	29.8

DBSCAN-SWA_8

114550 : 133125

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04319.1\|114550_118504_+	hypothetical protein	A0A2K9KZV5	Tupanvirus	5.0e-85	28.4
AWV04320.1\|118514_120131_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
AWV04321.1\|120118_124033_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	1.7e-69	30.7
AWV04322.1\|124029_133125_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	8.0e-70	19.8

DBSCAN-SWA_9

143926 : 145627

Organic_Lake_phycodnavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04323.1\|143926_145627_+	ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	1.1e-09	25.7

DBSCAN-SWA_10

172832 : 174767

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05265.1\|172832_173747_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.4e-35	42.9
AWV04339.1\|173792_174767_-	ABC transporter permease	G3M9Y4	Bacillus_virus	3.4e-19	25.8

DBSCAN-SWA_11

206200 : 207571

Burkholderia_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04357.1\|206200_207571_+	MFS transporter	Q6JIH2	Burkholderia_virus	4.7e-43	33.4

DBSCAN-SWA_12

216087 : 216894

Feldmannia_irregularis_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04361.1\|216087_216894_+	DNA-binding response regulator	Q6XM27	Feldmannia_irregularis_virus	1.0e-05	26.6

DBSCAN-SWA_13

225691 : 226939

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04366.1\|225691_226939_+	dienelactone hydrolase family protein	S4VXZ7	Pandoravirus	8.2e-10	33.3

DBSCAN-SWA_14

231675 : 234926

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04371.1\|231675_232194_-	(2Fe-2S)-binding protein	A0A0P0IVM8	Acinetobacter_phage	1.5e-13	32.2
AWV04372.1\|232190_234926_-	xanthine dehydrogenase family protein molybdopterin-binding subunit	A0A0P0I429	Acinetobacter_phage	2.6e-16	23.7

DBSCAN-SWA_15

243147 : 245079

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04381.1\|243147_245079_-	secretin	R9TEZ5	Vibrio_phage	2.0e-07	24.2

DBSCAN-SWA_16

252566 : 253610

Shigella_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04389.1\|252566_253610_+	glycosyltransferase	U5P087	Shigella_phage	1.5e-89	56.4

DBSCAN-SWA_17

258528 : 259962

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05278.1\|258528_259962_+	MFS transporter	A0A0M3UL24	Mycobacterium_phage	5.0e-27	30.0

DBSCAN-SWA_18

264786 : 266556

Feldmannia_species_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04398.1\|264786_266556_-	histidine kinase	B5LWN8	Feldmannia_species_virus	4.6e-06	28.8

DBSCAN-SWA_19

281309 : 290579

Acidovorax_phage(50.0%)

bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04410.1\|281309_282233_+	recombination-associated protein RdgC	A0A218M310	Acidovorax_phage	1.8e-54	38.7
AWV05282.1\|282482_283052_+\|bacteriocin	bacteriocin-protection protein	NA	NA	NA	NA
AWV04411.1\|283270_283435_-	zinc ribbon domain-containing protein	NA	NA	NA	NA
AWV04412.1\|283645_284374_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AWV04413.1\|284675_290579_-	excinuclease ABC subunit A	A0A1B1IVR3	uncultured_Mediterranean_phage	1.2e-191	38.3

DBSCAN-SWA_20

302168 : 305343

Feldmannia_irregularis_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04419.1\|302168_303002_+	DNA-binding response regulator	Q6XM27	Feldmannia_irregularis_virus	2.0e-07	28.2
AWV04420.1\|302994_305343_+	hybrid sensor histidine kinase/response regulator	A0A1V0SGX0	Hokovirus	2.8e-19	31.1

DBSCAN-SWA_21

326534 : 328406

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04436.1\|326534_328406_-	ABC transporter	G9BWD6	Planktothrix_phage	1.3e-14	31.3

DBSCAN-SWA_22

332909 : 334448

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04441.1\|332909_334448_-	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.8e-11	45.5

DBSCAN-SWA_23

344441 : 346028

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05287.1\|344441_346028_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	4.8e-15	34.2

DBSCAN-SWA_24

351274 : 352285

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04455.1\|351274_352285_-	dehydrogenase	A0A2K9L339	Tupanvirus	8.1e-08	23.9

DBSCAN-SWA_25

356255 : 357809

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04460.1\|356255_357809_-	D-xylose ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.7e-15	28.3

DBSCAN-SWA_26

363584 : 364949

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04464.1\|363584_364949_+	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	1.2e-22	23.7

DBSCAN-SWA_27

372674 : 376629

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04472.1\|372674_373574_-	alpha/beta hydrolase	A0A249XU20	Mycobacterium_phage	4.7e-07	26.7
AWV04473.1\|373580_374186_-	amino acid synthesis family protein	NA	NA	NA	NA
AWV04474.1\|374235_374751_-	glyoxalase	NA	NA	NA	NA
AWV04475.1\|374763_375801_-	glycosyl hydrolase	NA	NA	NA	NA
AWV04476.1\|375816_376629_-	short-chain dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	2.9e-08	27.5

DBSCAN-SWA_28

383039 : 384599

Anomala_cuprea_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04480.1\|383039_384599_-	D-xylose ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	4.6e-10	26.7

DBSCAN-SWA_29

393427 : 406839

Bacillus_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05290.1\|393427_394942_-	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.5e-16	25.5
AWV04488.1\|395003_395966_-	LacI family transcriptional regulator	NA	NA	NA	NA
AWV04489.1\|396489_397575_+	DNA topoisomerase IB	A0A0G2Y4T8	Acanthamoeba_polyphaga_mimivirus	3.2e-34	30.4
AWV04490.1\|397703_397931_-	hypothetical protein	NA	NA	NA	NA
AWV04491.1\|397946_398222_-	hypothetical protein	NA	NA	NA	NA
AWV04492.1\|398491_401731_+	AcrB/AcrD/AcrF family protein	S5VTK5	Leptospira_phage	3.6e-57	22.7
AWV04493.1\|401780_403142_+	efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
AWV04494.1\|403173_404703_+	RND transporter	NA	NA	NA	NA
AWV04495.1\|404683_406165_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	2.0e-18	26.9
AWV05291.1\|406161_406839_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	7.5e-34	36.1

DBSCAN-SWA_30

415672 : 421267

Faustovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04503.1\|415672_416830_+	histidinol-phosphate transaminase	A0A1X7QHI1	Faustovirus	6.2e-12	25.9
AWV04504.1\|416914_417166_-	hypothetical protein	NA	NA	NA	NA
AWV04505.1\|418805_419549_-	NmrA family transcriptional regulator	NA	NA	NA	NA
AWV05292.1\|419746_421267_+	PLP-dependent aminotransferase family protein	A0A1X9I5H2	Streptococcus_phage	1.1e-13	24.7

DBSCAN-SWA_31

425967 : 426750

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04510.1\|425967_426750_+	3-hydroxybutyrate dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	7.7e-06	27.6

DBSCAN-SWA_32

448580 : 456643

Pandoravirus(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04530.1\|448580_449225_-	phosphohydrolase	S4W232	Pandoravirus	1.5e-07	29.4
AWV04531.1\|449381_449789_+	DUF3224 domain-containing protein	NA	NA	NA	NA
AWV04532.1\|449926_451492_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	3.1e-14	34.1
AWV04533.1\|451798_452209_-	VOC family protein	NA	NA	NA	NA
AWV04534.1\|452695_454141_+	ATP-dependent helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.6e-52	34.0
AWV04535.1\|454709_454913_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	1.8e-20	71.6
AWV04536.1\|455191_455416_+	hypothetical protein	NA	NA	NA	NA
AWV04537.1\|455515_456643_-	aminotransferase	A0A0N9QIZ2	Chrysochromulina_ericina_virus	4.1e-85	43.3

DBSCAN-SWA_33

473066 : 474532

Anomala_cuprea_entomopoxvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04550.1\|473066_473768_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.0e-09	25.6
AWV04551.1\|473764_474532_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	8.9e-15	29.5

DBSCAN-SWA_34

480279 : 481677

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04557.1\|480279_481677_-	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	8.6e-16	25.7

DBSCAN-SWA_35

493474 : 496190

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04567.1\|493474_494824_-	RNA-directed DNA polymerase	Q7M2A9	Enterobacteria_phage	1.7e-08	27.4
AWV04568.1\|495224_496190_-	SDR family NAD(P)-dependent oxidoreductase	A0A291LA50	Escherichia_phage	8.0e-13	27.6

DBSCAN-SWA_36

501295 : 502384

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04573.1\|501295_502384_+	LacI family transcriptional regulator	C6ZCU4	Enterobacteria_phage	4.2e-18	28.2

DBSCAN-SWA_37

508387 : 512834

Moumouvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04581.1\|508387_509422_-	alpha/beta hydrolase	M1PGN2	Moumouvirus	1.8e-58	40.2
AWV04582.1\|509479_509905_-	organic hydroperoxide resistance protein	NA	NA	NA	NA
AWV04583.1\|510128_510695_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AWV04584.1\|510977_512834_+	multidrug ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.1e-29	26.3

DBSCAN-SWA_38

523928 : 524816

Burkholderia_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04593.1\|523928_524816_+	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	7.9e-23	29.8

DBSCAN-SWA_39

548592 : 549288

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04615.1\|548592_549288_+	ParA family protein	D4HTX7	Vibrio_phage	1.3e-20	31.4

DBSCAN-SWA_40

555857 : 557156

Megavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04620.1\|555857_557156_+	adenylosuccinate synthase	A0A2P1EKE7	Megavirus	2.6e-59	34.0

DBSCAN-SWA_41

573170 : 573695

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04632.1\|573170_573695_+	phosphohydrolase	A0A1B1IUF0	uncultured_Mediterranean_phage	7.3e-45	54.3

DBSCAN-SWA_42

583820 : 585488

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04638.1\|583820_585488_+	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	1.1e-81	40.1

DBSCAN-SWA_43

589770 : 594013

Aeromonas_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04642.1\|589770_591027_-	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	1.7e-95	54.2
AWV05305.1\|591148_594013_-	glycine dehydrogenase (aminomethyl-transferring)	M4QFZ1	Prochlorococcus_phage	3.8e-268	51.3

DBSCAN-SWA_44

600285 : 601971

Catovirus(100.0%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04648.1\|600285_601971_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	1.1e-60	29.6

DBSCAN-SWA_45

611841 : 613158

Geobacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04656.1\|611841_613158_+	thymidine phosphorylase	A0A0H3UZD4	Geobacillus_virus	1.3e-69	39.0

DBSCAN-SWA_46

618588 : 622176

uncultured_Caudovirales_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04662.1\|618588_620022_+	DUF4102 domain-containing protein	A0A2H4IYX8	uncultured_Caudovirales_phage	2.0e-44	30.2
AWV04663.1\|620292_620571_+	DNA-binding protein	Q6QIE5	Burkholderia_phage	2.8e-19	58.4
AWV05306.1\|620907_622176_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.7e-39	42.8

DBSCAN-SWA_47

627723 : 633476

Burkholderia_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04665.1\|627723_628002_+	HU family DNA-binding protein	Q6QIE5	Burkholderia_phage	1.8e-18	56.2
AWV04666.1\|627998_629153_+	DUF1016 domain-containing protein	A0A0U2BZN7	Salmonella_phage	1.2e-60	72.2
AWV04667.1\|629256_629691_+	hypothetical protein	NA	NA	NA	NA
AWV04668.1\|630785_633476_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.7e-52	25.3

DBSCAN-SWA_48

643400 : 649396

Leptospira_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04678.1\|643400_644966_-\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	2.4e-67	33.8
AWV04679.1\|644997_645348_-	IS66 family insertion sequence hypothetical protein	S5VXZ8	Leptospira_phage	1.9e-17	39.4
AWV04680.1\|645323_645866_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
AWV05307.1\|647338_649396_+	K(+)-transporting ATPase subunit B	E4ZFI9	Streptococcus_phage	7.2e-27	26.6

DBSCAN-SWA_49

660306 : 669357

Bacillus_virus(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05308.1\|660306_661683_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	1.1e-63	37.5
AWV04693.1\|661679_662756_+	hypothetical protein	NA	NA	NA	NA
AWV04694.1\|663823_665003_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.4e-59	41.8
AWV04695.1\|665710_665914_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	2.4e-20	70.1
AWV05309.1\|666022_668011_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	2.0e-34	38.1
AWV04696.1\|669216_669357_+	hypothetical protein	Q8W6Q2	Burkholderia_virus	1.4e-06	65.2

DBSCAN-SWA_50

678833 : 680741

Bathycoccus_sp._RCC1105_virus(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04704.1\|678833_680741_+\|protease	ATP-dependent zinc metalloprotease FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	1.0e-104	43.5

DBSCAN-SWA_51

692049 : 693684

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04716.1\|692049_693684_-	chaperonin GroEL	A0A240F779	uncultured_virus	3.0e-129	46.9

DBSCAN-SWA_52

698399 : 700115

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04722.1\|698399_700115_+	hypothetical protein	A0A1V0SGX0	Hokovirus	1.1e-41	30.7

DBSCAN-SWA_53

718576 : 719359

Aeromonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04734.1\|718576_719359_-	LuxR family transcriptional regulator	A0A1I9KF49	Aeromonas_phage	3.9e-10	26.8

DBSCAN-SWA_54

723389 : 726214

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04739.1\|723389_724598_-	pyridoxal-dependent decarboxylase, exosortase A system-associated	A0A2K9L0W9	Tupanvirus	5.1e-17	23.1
AWV04740.1\|724594_726214_-	acyl-CoA ligase (AMP-forming), exosortase A system-associated	Q75ZG1	Hepacivirus	1.9e-19	23.1

DBSCAN-SWA_55

735570 : 737062

Brazilian_cedratvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04749.1\|735570_736305_+	branched-chain amino acid ABC transporter substrate-binding protein	A0A2R8FG22	Brazilian_cedratvirus	2.4e-09	28.3
AWV04750.1\|736291_737062_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-14	27.2

DBSCAN-SWA_56

756550 : 758404

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04769.1\|756550_758404_+	DNA replication protein	M4QC51	Vibrio_phage	3.6e-09	34.5

DBSCAN-SWA_57

765064 : 768225

Emiliania_huxleyi_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04772.1\|765064_767266_-	chromosome partitioning protein ParB	G8DH78	Emiliania_huxleyi_virus	6.1e-24	34.0
AWV04773.1\|767391_768225_-	hypothetical protein	A0A2C9CYF8	Yersinia_phage	6.9e-45	37.2

DBSCAN-SWA_58

773576 : 779682

Stx2-converting_phage(40.0%)

transposase,integrase

attL 774221:774237|attR 787748:787764

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04776.1\|773576_774494_+	hypothetical protein	S5VKI3	Leptospira_phage	9.6e-32	32.1
774221:774237	attL	NA	NA	NA	NA
AWV04777.1\|774490_775525_+	hypothetical protein	NA	NA	NA	NA
AWV04778.1\|775623_775875_+	hypothetical protein	NA	NA	NA	NA
AWV04779.1\|776117_776318_+	hypothetical protein	NA	NA	NA	NA
AWV04780.1\|776394_776808_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	5.3e-06	29.8
AWV04781.1\|776804_777152_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZDM8	Stx2-converting_phage	9.2e-36	65.7
AWV04782.1\|777493_778753_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.1e-44	45.0
AWV04783.1\|778764_779682_+\|integrase	integrase	A0A0K2CP59	Brevibacillus_phage	6.2e-15	26.6
787748:787764	attR	NA	NA	NA	NA

DBSCAN-SWA_59

788084 : 790142

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04791.1\|788084_790142_+	radical SAM protein	A0A0M4R1U9	Streptomyces_phage	8.8e-17	26.2

DBSCAN-SWA_60

793353 : 798013

uncultured_virus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04794.1\|793353_794928_+\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	3.7e-124	46.6
AWV04795.1\|796926_798013_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	4.4e-44	36.8

DBSCAN-SWA_61

803935 : 804499

Wolbachia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04802.1\|803935_804499_-	Hsp20/alpha crystallin family protein	A0A1B2LRT2	Wolbachia_phage	1.0e-12	32.5

DBSCAN-SWA_62

813573 : 814377

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04809.1\|813573_814377_+	ectoine/hydroxyectoine ABC transporter ATP-binding protein EhuA	G9BWD6	Planktothrix_phage	2.9e-32	39.8

DBSCAN-SWA_63

823242 : 825474

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04818.1\|823242_825474_+	lipopolysaccharide biosynthesis protein	A0A1X9I5D6	Streptococcus_phage	2.4e-12	29.7

DBSCAN-SWA_64

844870 : 846343

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04829.1\|844870_846343_+	peptidase S8	U5J9E4	Bacillus_phage	4.7e-12	27.2

DBSCAN-SWA_65

854925 : 856221

Burkholderia_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04836.1\|854925_856221_+	citrate-proton symporter	Q6JIH2	Burkholderia_virus	1.8e-60	37.0

DBSCAN-SWA_66

865512 : 866697

Aeropyrum_coil-shaped_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04844.1\|865512_866697_+	MSMEG_0565 family glycosyltransferase	J7Q7I8	Aeropyrum_coil-shaped_virus	9.9e-05	29.9

DBSCAN-SWA_67

878265 : 879015

Chrysochromulina_ericina_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04853.1\|878265_879015_+	short-chain dehydrogenase	A0A0N9R355	Chrysochromulina_ericina_virus	5.6e-06	24.1

DBSCAN-SWA_68

882923 : 888244

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04857.1\|882923_883643_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	7.5e-32	33.2
AWV05336.1\|883642_885136_+	two-component sensor histidine kinase	NA	NA	NA	NA
AWV04858.1\|885164_886265_-	AraC family transcriptional regulator	NA	NA	NA	NA
AWV04859.1\|886609_888244_+	long-chain-fatty-acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.5e-32	29.9

DBSCAN-SWA_69

916350 : 917859

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05338.1\|916350_917859_+	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.3e-13	28.4

DBSCAN-SWA_70

920924 : 921761

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04882.1\|920924_921761_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.6e-25	35.3

DBSCAN-SWA_71

930771 : 931542

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04890.1\|930771_931542_+	DNA-binding transcriptional repressor DeoR	A0A077SK06	Escherichia_phage	2.7e-19	31.2

DBSCAN-SWA_72

937575 : 938325

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04896.1\|937575_938325_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-30	40.7

DBSCAN-SWA_73

943488 : 944325

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04902.1\|943488_944325_+	alpha/beta hydrolase	A0A249XU20	Mycobacterium_phage	2.0e-07	25.8

DBSCAN-SWA_74

947897 : 954152

Escherichia_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04906.1\|947897_948902_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	5.1e-79	45.7
AWV04907.1\|948898_949783_-	dTDP-4-dehydrorhamnose reductase	A0A1D7XFA3	Escherichia_phage	2.8e-28	34.5
AWV04908.1\|949779_950352_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	3.1e-49	53.4
AWV04909.1\|950348_951245_-	glucose-1-phosphate thymidylyltransferase	K7QKA7	Escherichia_phage	4.4e-98	58.4
AWV04910.1\|951286_952657_-	MFS transporter	A0A0M3UL24	Mycobacterium_phage	4.3e-28	29.4
AWV04911.1\|952653_953373_-	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	3.7e-15	29.2
AWV04912.1\|953369_954152_-	ABC transporter ATP-binding protein	A0A1M7XV31	Cedratvirus	1.0e-10	27.1

DBSCAN-SWA_75

962854 : 964828

Oenococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04922.1\|962854_964033_+	L-rhamnonate dehydratase	Q6A202	Oenococcus_phage	1.6e-26	26.8
AWV04923.1\|964042_964828_+	short-chain dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	1.8e-15	28.7

DBSCAN-SWA_76

986232 : 987762

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04938.1\|986232_987762_+	nitrate reductase subunit beta	A0A077SL61	Escherichia_phage	1.7e-20	37.5

DBSCAN-SWA_77

991364 : 1054998

Stx2-converting_phage(27.27%)

transposase,integrase

attL 1028239:1028255|attR 1059692:1059708

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04943.1\|991364_993086_+\|integrase	integrase	NA	NA	NA	NA
AWV04944.1\|993325_993649_+	competence protein TfoX	NA	NA	NA	NA
AWV04945.1\|993733_994654_+	hypothetical protein	NA	NA	NA	NA
AWV04946.1\|994679_995831_-	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
AWV04947.1\|995871_997101_-	amino acid dehydrogenase	NA	NA	NA	NA
AWV04948.1\|997332_998745_+	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
AWV04949.1\|998755_1000930_-	hypothetical protein	NA	NA	NA	NA
AWV04950.1\|1000922_1001237_-	transcriptional regulator	NA	NA	NA	NA
AWV04951.1\|1001683_1003108_+	2-aminoadipate aminotransferase	NA	NA	NA	NA
AWV04952.1\|1003825_1004341_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AWV04953.1\|1004476_1005382_-	LysR family transcriptional regulator	NA	NA	NA	NA
AWV04954.1\|1005706_1006507_-	phosphodiesterase	NA	NA	NA	NA
AWV04955.1\|1006909_1008112_+	hypothetical protein	NA	NA	NA	NA
AWV05342.1\|1008123_1008747_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.2e-09	25.4
AWV04956.1\|1009076_1009784_-	pirin family protein	NA	NA	NA	NA
AWV04957.1\|1009867_1010632_-	oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.2e-14	31.4
AWV04958.1\|1010773_1011691_+	LysR family transcriptional regulator	NA	NA	NA	NA
AWV04959.1\|1011852_1012818_+	alpha/beta hydrolase	L7RDF8	Acanthamoeba_polyphaga_moumouvirus	5.0e-55	39.5
AWV04960.1\|1012851_1013247_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
AWV04961.1\|1013277_1013643_+	hypothetical protein	NA	NA	NA	NA
AWV04962.1\|1013639_1015202_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	4.4e-154	55.3
AWV04963.1\|1015231_1015579_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBY2	Stx2-converting_phage	1.6e-40	72.9
AWV04964.1\|1015575_1015983_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	7.5e-13	45.8
AWV04965.1\|1016248_1017802_-	PLP-dependent aminotransferase family protein	A0A1X9I5H2	Streptococcus_phage	3.1e-22	24.6
AWV04966.1\|1017825_1018878_+	low-specificity L-threonine aldolase	NA	NA	NA	NA
AWV04967.1\|1018951_1019725_+	arylamine N-acetyltransferase	NA	NA	NA	NA
AWV05343.1\|1020879_1022148_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.9e-40	43.1
AWV04968.1\|1024448_1024976_-	2'-5' RNA ligase family protein	NA	NA	NA	NA
AWV04969.1\|1025051_1025618_-	hypothetical protein	NA	NA	NA	NA
AWV04970.1\|1025730_1026447_-	alpha/beta hydrolase	NA	NA	NA	NA
AWV04971.1\|1028155_1028362_-	hypothetical protein	NA	NA	NA	NA
1028239:1028255	attL	NA	NA	NA	NA
AWV04972.1\|1028724_1030617_-	SAM-dependent methyltransferase	NA	NA	NA	NA
AWV04973.1\|1030755_1032015_-	MFS transporter	NA	NA	NA	NA
AWV05344.1\|1032606_1033224_-	haloacid dehalogenase	NA	NA	NA	NA
AWV04974.1\|1033429_1033771_-	hypothetical protein	NA	NA	NA	NA
AWV05345.1\|1034113_1034581_-	RidA family protein	NA	NA	NA	NA
AWV04975.1\|1034824_1035451_-\|integrase	integrase	A0A1S5SFL0	Streptococcus_phage	1.6e-09	29.0
AWV04976.1\|1035891_1036818_-	LysR family transcriptional regulator	NA	NA	NA	NA
AWV04977.1\|1037237_1038200_+	esterase	NA	NA	NA	NA
AWV04978.1\|1038271_1039594_+	cation:proton symporter	NA	NA	NA	NA
AWV04979.1\|1039672_1040788_+	porin	NA	NA	NA	NA
AWV05346.1\|1041877_1043254_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	7.1e-31	33.5
AWV04980.1\|1044015_1044273_-	molybdopterin converting factor subunit 1	NA	NA	NA	NA
AWV04981.1\|1044325_1044898_-	molybdenum cofactor biosynthesis protein MoaE	NA	NA	NA	NA
AWV04982.1\|1044944_1046069_-	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
AWV05347.1\|1046044_1046245_-	hypothetical protein	NA	NA	NA	NA
AWV04983.1\|1046268_1047483_-	molybdopterin molybdenumtransferase MoeA	NA	NA	NA	NA
AWV04984.1\|1047479_1048352_-	formate dehydrogenase accessory sulfurtransferase FdhD	NA	NA	NA	NA
AWV04985.1\|1048774_1050175_+	cytochrome ubiquinol oxidase subunit I	NA	NA	NA	NA
AWV04986.1\|1050177_1051185_+	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
AWV04987.1\|1051337_1052258_+	hypothetical protein	NA	NA	NA	NA
AWV04988.1\|1052354_1052948_+	SMI1/KNR4 family protein	NA	NA	NA	NA
AWV04989.1\|1053031_1053418_+	VOC family protein	NA	NA	NA	NA
AWV05348.1\|1053945_1054998_+\|transposase	transposase	A0A0R8V9X2	Thermobifida_phage	7.1e-31	36.6
1059692:1059708	attR	NA	NA	NA	NA

DBSCAN-SWA_78

1059612 : 1060711

Leptospira_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04991.1\|1059612_1060711_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	9.1e-37	37.1

DBSCAN-SWA_79

1070187 : 1073031

Agrobacterium_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV04999.1\|1070187_1073031_-\|protease	Clp protease ClpC	A0A223W0B1	Agrobacterium_phage	9.6e-123	35.7

DBSCAN-SWA_80

1082619 : 1087924

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05007.1\|1082619_1084926_+	hybrid sensor histidine kinase/response regulator	W8CYF6	Bacillus_phage	3.1e-18	27.9
AWV05008.1\|1086916_1087399_-	PRC-barrel domain containing protein	NA	NA	NA	NA
AWV05009.1\|1087492_1087924_-	CBS domain-containing protein	A0A2I6B2H4	Macacine_betaherpesvirus	4.1e-17	40.5

DBSCAN-SWA_81

1092753 : 1094426

Sinorhizobium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05017.1\|1092753_1093110_-	hypothetical protein	A0A0F6TH17	Sinorhizobium_phage	1.1e-20	58.2
AWV05351.1\|1093334_1093703_+	hypothetical protein	NA	NA	NA	NA
AWV05018.1\|1093877_1094426_+	type 1 glutamine amidotransferase	A0A0N7KVR4	Yellowstone_lake_phycodnavirus	4.2e-19	36.3

DBSCAN-SWA_82

1119468 : 1123435

Trichoplusia_ni_ascovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05034.1\|1119468_1120245_-	oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	7.6e-22	36.0
AWV05035.1\|1120403_1121306_+	LysR family transcriptional regulator	NA	NA	NA	NA
AWV05036.1\|1121526_1121931_+	hypothetical protein	NA	NA	NA	NA
AWV05037.1\|1122298_1123435_+	muconate cycloisomerase	Q6A202	Oenococcus_phage	1.1e-08	23.2

DBSCAN-SWA_83

1127439 : 1128216

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05042.1\|1127439_1128216_+	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase	W8CYX9	Bacillus_phage	5.8e-06	47.2

DBSCAN-SWA_84

1139186 : 1140233

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05047.1\|1139186_1140233_-	acyltransferase	A0A2H4JA46	uncultured_Caudovirales_phage	4.6e-14	29.7

DBSCAN-SWA_85

1145770 : 1147306

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05050.1\|1145770_1147306_+	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	7.7e-42	27.1

DBSCAN-SWA_86

1167801 : 1170480

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05063.1\|1167801_1170480_-	hypothetical protein	G3MA91	Bacillus_virus	1.5e-16	33.1

DBSCAN-SWA_87

1181649 : 1183839

Feldmannia_species_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05074.1\|1181649_1183839_+	hybrid sensor histidine kinase/response regulator	B5LWA6	Feldmannia_species_virus	6.3e-05	33.3

DBSCAN-SWA_88

1200085 : 1200922

Pelagibacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05088.1\|1200085_1200922_+	spermidine synthase	M1ICM1	Pelagibacter_phage	4.1e-05	38.8

DBSCAN-SWA_89

1218754 : 1219519

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05106.1\|1218754_1219519_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.6e-30	37.5

DBSCAN-SWA_90

1234980 : 1236006

Cyanophage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05117.1\|1234980_1236006_-	phosphate ABC transporter substrate-binding protein PstS	M4QHS4	Cyanophage	6.9e-47	35.4

DBSCAN-SWA_91

1240891 : 1241869

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05123.1\|1240891_1241869_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	9.2e-33	42.7

DBSCAN-SWA_92

1253301 : 1254177

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05133.1\|1253301_1254177_-	alpha/beta hydrolase	A0A2K9KZN8	Tupanvirus	1.2e-07	29.9

DBSCAN-SWA_93

1280076 : 1280577

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05148.1\|1280076_1280577_-	(2Fe-2S)-binding protein	A0A0P0IVM8	Acinetobacter_phage	2.4e-08	28.7

DBSCAN-SWA_94

1289191 : 1295591

Orpheovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05156.1\|1289191_1290463_+	pyridine nucleotide-disulfide oxidoreductase	A0A2I2L5E1	Orpheovirus	1.2e-29	29.9
AWV05157.1\|1290506_1295591_-	histidine kinase	W8CYF6	Bacillus_phage	2.2e-05	24.0

DBSCAN-SWA_95

1303188 : 1304163

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05163.1\|1303188_1304163_-	alpha/beta hydrolase	A0A249XU20	Mycobacterium_phage	3.4e-11	25.7

DBSCAN-SWA_96

1319325 : 1321618

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05176.1\|1319325_1320117_+	histidine/lysine/arginine/ornithine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.7e-32	37.7
AWV05177.1\|1320124_1321618_+	histidine ammonia-lyase	A0A1V0S940	Catovirus	1.0e-51	33.7

DBSCAN-SWA_97

1350022 : 1355584

Synechococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05199.1\|1350022_1351639_-	tryptophan 7-halogenase	A0A1Z1LWL6	Synechococcus_phage	2.5e-59	32.6
AWV05200.1\|1352742_1353342_-	LysE family translocator	NA	NA	NA	NA
AWV05201.1\|1354360_1355584_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	7.2e-51	31.1

DBSCAN-SWA_98

1367753 : 1413395

Paenibacillus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05211.1\|1367753_1369751_+	asparagine synthase (glutamine-hydrolyzing)	A0A0G2Y824	Acanthamoeba_polyphaga_mimivirus	1.3e-28	27.8
AWV05212.1\|1369743_1379469_+	polyketide synthase	D0R7J2	Paenibacillus_phage	8.9e-27	29.7
AWV05213.1\|1379469_1409994_+	hypothetical protein	D0R7J2	Paenibacillus_phage	3.8e-39	32.7
AWV05214.1\|1410054_1410768_+	hypothetical protein	NA	NA	NA	NA
AWV05215.1\|1410802_1411825_+	NADP-dependent oxidoreductase	NA	NA	NA	NA
AWV05371.1\|1412126_1413395_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.7e-39	42.8

DBSCAN-SWA_99

1433917 : 1436896

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05230.1\|1433917_1436896_+	pyrogallol hydroxytransferase large subunit	A0A077SK27	Escherichia_phage	1.4e-52	28.2

DBSCAN-SWA_100

1443480 : 1446162

Caulobacter_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05235.1\|1443480_1444038_+	peptide deformylase	K4JRM9	Caulobacter_phage	2.1e-10	33.1
AWV05236.1\|1444034_1444982_+	branched-chain amino acid transferase	NA	NA	NA	NA
AWV05237.1\|1444971_1446162_+	glycine C-acetyltransferase	D2TEZ5	Emiliania_huxleyi_virus	2.3e-25	27.5

DBSCAN-SWA_101

1461320 : 1466279

Burkholderia_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05248.1\|1461320_1462355_-	acyltransferase	A9YX16	Burkholderia_phage	2.2e-24	32.6
AWV05249.1\|1464499_1464790_-	hypothetical protein	NA	NA	NA	NA
AWV05250.1\|1464902_1466279_-\|tRNA	cysteine--tRNA ligase	F1C984	Moumouvirus	3.4e-33	30.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. CP029827

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP029827_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029827_1

6605-6698

Orphan

Consensus_repeat	Method
GACAAATTCTGGGTTAGTCGGGCTTTTTCCGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029827_1

>merge|CP029827|1|6605-6698|CRISPRCasFinder
GACAAATTCTGGGTTAGTCGGGCTTTTTCCGGGTTAGTCGGGCTTTTTTCGGGATATACCTGACAAATTCCGGGTTAGTCGGGCTTTTTCCGGG

>CP029827|1|1|6605-6698|CRISPRCasFinder
GACAAATTCTGGGTTAGTCGGGCTTTTTCCGGG	TTAGTCGGGCTTTTTTCGGGATATACCT
GACAAATTCCGGGTTAGTCGGGCTTTTTCCGGG

Protein	Signature genes	Signature genes Name	Protein_function
CP029827.1\|AWV05377.1\|3735_3996_+\|hypothetical-protein	unknown	unknown	unknown
CP029827.1\|AWV05386.1\|14004_14322_+\|hypothetical-protein	unknown	unknown	unknown
CP029827.1\|AWV05387.1\|14278_14602_+\|hypothetical-protein	unknown	unknown	unknown
CP029827.1\|AWV05380.1\|6790_7582_+\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
CP029827.1\|AWV05384.1\|12017_12980_-\|integrase	unknown	unknown	gnl\|CDD\|271196
CP029827.1\|AWV05385.1\|12972_13371_-\|DUF2513-domain-containing-protein	unknown	unknown	gnl\|CDD\|378481
CP029827.1\|AWV05379.1\|5374_5614_+\|hypothetical-protein	unknown	unknown	unknown
CP029827.1\|AWV05378.1\|4488_5391_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372340
CP029827.1\|AWV05382.1\|8659_8905_+\|toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|310261
CP029827.1\|AWV05383.1\|10641_11529_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227645
CP029827.1\|AWV05388.1\|13399_13741_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375742
CP029827.1\|AWV05381.1\|7975_8623_+\|cobyrinic-acid-ac-diamide-synthase	unknown	unknown	gnl\|CDD\|222854

Protein	Function_ID	Function_description	E-value
CP029827.1\|AWV05385.1\|12972_13371_-\|DUF2513-domain-containing-protein	gnl\|CDD\|378481	pfam10711, DUF2513, Hypothetical protein (DUF2513). This family is found in bacteria. The function is not known.	3.4996e-30
CP029827.1\|AWV05384.1\|12017_12980_-\|integrase	gnl\|CDD\|271196	cd01196, INT_C_like_6, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	5.02738e-98
CP029827.1\|AWV05378.1\|4488_5391_+\|hypothetical-protein	gnl\|CDD\|372340	pfam12835, Integrase_1, Integrase. This is a family of DNA-binding prophage integrases found in Proteobacteria.	2.24161e-18
CP029827.1\|AWV05380.1\|6790_7582_+\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	1.27479e-51
CP029827.1\|AWV05382.1\|8659_8905_+\|toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|310261	pfam05534, HicB, HicB family. This family consists of several bacterial HicB related proteins. The function of HicB is unknown although it is thought to be involved in pilus formation. It has been speculated that HicB performs a function antagonistic to that of pili and yet is necessary for invasion of certain niches.	0.000203319
CP029827.1\|AWV05383.1\|10641_11529_-\|hypothetical-protein	gnl\|CDD\|227645	COG5340, COG5340, Predicted transcriptional regulator [Transcription].	9.73779e-07
CP029827.1\|AWV05388.1\|13399_13741_-\|hypothetical-protein	gnl\|CDD\|375742	pfam18315, VCH_CASS14, Integron cassette protein VCH_CASS1 chain. This domain is a chain that forms part of the integron cassette protein VCH_CASS14 present in Vibrio cholerae. In each monomer lies a deep binding pocket for small molecule substrates formed by helices alpha-1 and alpha-2 and residues from the central four strands of the beta-sheet. The pocket is extensively lined with hydrophobic side chains.	3.79534e-27
CP029827.1\|AWV05381.1\|7975_8623_+\|cobyrinic-acid-ac-diamide-synthase	gnl\|CDD\|222854	PHA02518, PHA02518, ParA-like protein; Provisional.	8.91893e-34

>CP029827.1|AWV05379.1|5374_5614_+|hypothetical-protein
MNRKTEFITSARLQEGSLWKVVNEVVGGSHLQEVVTDSNALPRIKVSHEAFAVAKRLRRKGETVRDVVERLIFAATGNR
>CP029827.1|AWV05378.1|4488_5391_+|hypothetical-protein
MSKPTSSKPRSIEAKFMSAALHKGAATLTKQKMRTTFLAFAAHAKQRRYGQVDPATVTEKQLRNYVGSRIDAGISARTIQNEMSHLRRAIRGAGRGEWADALTNADLGVPSGTRIGTGKVVDARVLAHALERAAPDTRTWIQLERCLGLRREEMIESHKSLAQWEAALARGQSFITIRHGTKGGRVRDTHIPEPYRPRALDAVRAALAIVADRRYLVDAPTNHAAKQQVQGRFAALGLERENSGHSLRRAFCRDNFEHYLSERCSRKEALALCSRDLGHGEGRGRWVWNNYLRSTYESEN
>CP029827.1|AWV05377.1|3735_3996_+|hypothetical-protein
MLHFVFKNAGKLLALCLVLYLASTSYLIGGIVAVVFLKKAFTGKLALSKHFAFVTPTEPTRLVKQVKRHYANPIGATPVKARSRVR
>CP029827.1|AWV05380.1|6790_7582_+|replication-initiation-protein
MGDLAELHDPATRERSVTIKNELVRRIQRMKLSEKRLLALAIAKCNPKAKILKDRAMRPDPMTGDAPGWTIRVTAKEFIEAYPHIEAKHAYSELKEAAENLFECRVEWDEEVIERGKKTTKHRVVRWIYEKVDTTTAGWVDIKFSPSIAPYLLGIESEFTKYKLRHAADLRSIYSWRLLEVMAQYRDKGFVSIGYDEFCQAMGAPDSCVKDSGQLRRRVIEPAVKELQEKNSLAIEWEPVKPSGRKVTGFRFKFKPDPQGRLF
>CP029827.1|AWV05381.1|7975_8623_+|cobyrinic-acid-ac-diamide-synthase
MIVLIGGEKGGVGKSTLASNLAVHLVREQVDVVLVDTDGQATGARFVERRDESGIQPSIPCVQRTGDVAATLRDLAKRYQVVIVDAGGRDSRELRTALAVANLLLTPIRASQADLETLPKVNELVGLARGLNPELKASAVLSMAPSNPAIREVEDARELLAQFDQLELADTVIRDRKVYRDALLAGQGVVELNNSLARAEIQLLAQEFFELEPSA
>CP029827.1|AWV05382.1|8659_8905_+|toxin-antitoxin-system-HicB-family-antitoxin
MSKFKISAKSGGQPPSQPVTHAEFAAGAAMVQSQVGNRPAKPIRLNLDLDPELHRRLKVRAAETGISIAELVRGLITREIG
>CP029827.1|AWV05383.1|10641_11529_-|hypothetical-protein
MNRSRIQIAKADIIKHFDELPTHVLKLKEIRAILADQRAFWRLAQSTTADNFIAFLQLHAKLRKVEFPFPQRAEQCYAWGDVPLLTILLSLRKNLYLSHYTAMRLHGLTEQSPTTIYTTDERSNTYQDERATLDQLAIDQAFSRPPRVSHNWVEHAGKKIYLLNGAYTGHLGVVTEPVTDEGGQEVLARLTNLERTLIDITVRPVYAGGVFEVAKAFELAKDRVSINRLVAMLRKLNFAYPYHQAIGYYLERAGYKPNQIDLIRRLPIERDFYLTHEMGDTRYVSNWRLSVPSGF
>CP029827.1|AWV05384.1|12017_12980_-|integrase
MANAVLALPTEATVPVLVASAGERAGLRFLEFFAAAIRNQHTRRAYARAASDFLAWCAGAGVPSIAAVQPLHVASWVELQTRTHAAPTVKQRLAAIRHLFDWLVTGQVVPHNPAASVRGPSHVTKTGKTPVLEAAEARQLLDSIDVTTPAGLRDRALIALMVFSFARIGAALAMRVDDVYVQQRRLWVRLREKGGKAHAMPCHHTLEAALHAYLDGTGIGADLKGPLFRTIARGTRQLSRTPLPQANAYAMVRRRAAAAGIATAIGNHTFRATGITAYLQNGGTLESAAAMANHASTRTTQLYDRRHDALSLDEVERIRL
>CP029827.1|AWV05385.1|12972_13371_-|DUF2513-domain-containing-protein
MKRDMDLIRELMLKLEELPVPTAGMVVVDAAKVGVEGYTAEQIDYHLSLLEQARFIHAGGLDMGMSGPGFGPGVGFCSLTWAGHDFLDAVRSPDVWDRTTQAATAAGGFTVELLVFAAKTYLEGKIKGLIGG
>CP029827.1|AWV05388.1|13399_13741_-|hypothetical-protein
MARHLRTQKQIDAFIAQVIQQAIHHASQVAQIIQPLANAVLGHSAFSRLEVYERNGNLARTCWVTVGTNRWVFSYSYGQHVIELRKDSTRGPVVFQFDNHTSAAALSQQVSRL
>CP029827.1|AWV05386.1|14004_14322_+|hypothetical-protein
MNPNLHDPKTSVKVVGSSGQISLGKEYAGRQVLVEEREPGVWLVRTALVIPENEAWLHAPQAQRDLQEALAWAQGNAPKESNLDALLNELGNEEEKRRPRKVGPK
>CP029827.1|AWV05387.1|14278_14602_+|hypothetical-protein
MRKKSDDLVKLDLNNPVFQRQWVALDKAEASRVLTTLKKLLPMSWNQVYQDSGLKWEKITSVQPPAGVDAMYSLRITQARRATAYRDGEYMRLLTIAPDHDATYGKK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP029827_1	1.1\|6638\|28\|CP029827\|CRISPRCasFinder	6638-6665	28	NZ_CP029827	Burkholderia sp. JP2-270 plasmid p1, complete sequence	6638-6665	0	1.0
CP029827_1	1.1\|6638\|28\|CP029827\|CRISPRCasFinder	6638-6665	28	NZ_CP029827	Burkholderia sp. JP2-270 plasmid p1, complete sequence	6618-6645	6	0.786

1. spacer 1.1|6638|28|CP029827|CRISPRCasFinder matches to NZ_CP029827 (Burkholderia sp. JP2-270 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

ttagtcgggcttttttcgggatatacct	CRISPR spacer
ttagtcgggcttttttcgggatatacct	Protospacer
****************************

2. spacer 1.1|6638|28|CP029827|CRISPRCasFinder matches to NZ_CP029827 (Burkholderia sp. JP2-270 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.786

ttagtcgggcttttttcgggatatacct	CRISPR spacer
ttagtcgggctttttccgggttagtcgg	Protospacer
***************.**** **  *

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. CP029828

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

17553 : 69962

Leptospira_phage(27.27%)

tRNA,coat,transposase,integrase

attL 12231:12248|attR 78948:78965

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
12231:12248	attL	NA	NA	NA	NA
AWV05396.1\|17553_18673_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	7.3e-50	40.3
AWV05689.1\|18902_20198_+\|transposase	IS701 family transposase	NA	NA	NA	NA
AWV05397.1\|20437_21430_-\|transposase	IS5 family transposase	E5E3P6	Burkholderia_phage	1.1e-158	86.1
AWV05398.1\|21765_22896_+\|transposase	IS110 family transposase	NA	NA	NA	NA
AWV05399.1\|23346_23802_-	SCPU domain-containing protein	NA	NA	NA	NA
AWV05400.1\|23798_26189_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
AWV05401.1\|26206_26938_-	molecular chaperone	NA	NA	NA	NA
AWV05402.1\|26941_27523_-\|coat	spore coat protein	NA	NA	NA	NA
AWV05403.1\|28293_29429_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.6e-10	25.7
AWV05404.1\|29777_30908_-\|transposase	IS110 family transposase	NA	NA	NA	NA
AWV05405.1\|31102_31369_+	DUF1488 domain-containing protein	NA	NA	NA	NA
AWV05406.1\|31739_32036_+	H-NS histone family protein	NA	NA	NA	NA
AWV05407.1\|32058_32268_+	hypothetical protein	NA	NA	NA	NA
AWV05408.1\|32279_32465_+	hypothetical protein	NA	NA	NA	NA
AWV05409.1\|32482_32809_+	hypothetical protein	NA	NA	NA	NA
AWV05410.1\|33051_33468_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
AWV05411.1\|33464_33806_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZDM8	Stx2-converting_phage	1.2e-35	66.7
AWV05412.1\|33857_35408_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	6.8e-155	56.2
AWV05413.1\|35632_35884_+	hypothetical protein	NA	NA	NA	NA
AWV05414.1\|35918_37448_-\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	1.6e-124	46.3
AWV05415.1\|37842_38238_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
AWV05416.1\|38313_38580_-	helicase	NA	NA	NA	NA
AWV05417.1\|39205_39913_-	hypothetical protein	NA	NA	NA	NA
AWV05418.1\|39914_40559_-	hypothetical protein	NA	NA	NA	NA
AWV05419.1\|41184_42675_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
AWV05690.1\|43538_44701_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	1.2e-84	53.2
AWV05420.1\|44878_45535_+	DNA-binding response regulator	NA	NA	NA	NA
AWV05421.1\|45990_46974_-	AraC family transcriptional regulator	NA	NA	NA	NA
AWV05422.1\|47235_48288_+	phenylacetaldoxime dehydratase	NA	NA	NA	NA
AWV05423.1\|48381_49245_+	transporter	NA	NA	NA	NA
AWV05424.1\|49327_50374_+	carbon-nitrogen hydrolase family protein	NA	NA	NA	NA
AWV05425.1\|50249_50567_-	hypothetical protein	S5WIU1	Leptospira_phage	5.3e-06	40.7
AWV05426.1\|50928_52608_+\|integrase	integrase	NA	NA	NA	NA
AWV05427.1\|52604_55586_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	4.6e-75	26.6
AWV05428.1\|55960_56230_+	hypothetical protein	NA	NA	NA	NA
AWV05429.1\|56276_56945_-\|tRNA	glutamyl-tRNA amidotransferase	NA	NA	NA	NA
AWV05430.1\|56957_58244_-	hypothetical protein	NA	NA	NA	NA
AWV05431.1\|58228_59242_-	hypothetical protein	NA	NA	NA	NA
AWV05432.1\|59406_60108_-	formylglycine-generating enzyme family protein	A0A7F1	Microcystis_virus	1.0e-33	43.6
AWV05433.1\|61325_61841_-	flavodoxin	NA	NA	NA	NA
AWV05434.1\|62046_62589_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
AWV05435.1\|62805_63282_-	universal stress protein	NA	NA	NA	NA
AWV05436.1\|63247_63811_-	hypothetical protein	NA	NA	NA	NA
AWV05437.1\|63953_65270_-	erythromycin esterase family protein	NA	NA	NA	NA
AWV05438.1\|65366_66080_-	phosphoribosyltransferase	NA	NA	NA	NA
AWV05439.1\|66636_66762_-	hypothetical protein	NA	NA	NA	NA
AWV05440.1\|67511_69419_-	cell division protein FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	7.2e-106	44.3
AWV05441.1\|69452_69962_-\|tRNA	glutamyl-tRNA amidotransferase	NA	NA	NA	NA
78948:78965	attR	NA	NA	NA	NA

DBSCAN-SWA_2

119188 : 172114

Leptospira_phage(28.57%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05477.1\|119188_119623_+	IS66 family insertion sequence hypothetical protein	B6DZU5	Stx2-converting_phage	1.6e-13	43.6
AWV05478.1\|119619_119967_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBY2	Stx2-converting_phage	2.0e-35	63.6
AWV05479.1\|120018_121563_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.7e-137	49.0
AWV05480.1\|121574_122171_+	plasmid pRiA4b ORF-3 family protein	A0A2H4PDG5	Mycobacterium_phage	6.9e-23	33.5
AWV05481.1\|122896_123970_-	arsenical-resistance protein	NA	NA	NA	NA
AWV05482.1\|124034_124529_-	arsenate reductase ArsC	A0A2H4J8A6	uncultured_Caudovirales_phage	7.7e-28	47.1
AWV05483.1\|124546_125041_-	arsenate reductase ArsC	A0A2H4J8A6	uncultured_Caudovirales_phage	8.0e-25	41.3
AWV05484.1\|125050_125530_-	glyoxalase/bleomycin resistance/dioxygenase family protein	NA	NA	NA	NA
AWV05485.1\|125526_125868_-	transcriptional regulator	NA	NA	NA	NA
AWV05486.1\|126002_128492_-	arsenate reductase (azurin) large subunit	NA	NA	NA	NA
AWV05487.1\|128503_129022_-	arsenate reductase (azurin) small subunit	NA	NA	NA	NA
AWV05488.1\|129474_129738_-	hypothetical protein	NA	NA	NA	NA
AWV05489.1\|130436_131246_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
AWV05696.1\|131422_132691_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.7e-39	42.8
AWV05490.1\|133198_133357_+	DUF3309 domain-containing protein	NA	NA	NA	NA
AWV05491.1\|133508_133820_+	transporter	NA	NA	NA	NA
AWV05492.1\|134157_135267_+	glycosyltransferase family 4 protein	A0A1D8KU90	Synechococcus_phage	4.6e-12	29.7
AWV05493.1\|136103_136604_-	hypothetical protein	NA	NA	NA	NA
AWV05494.1\|136627_137020_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
AWV05495.1\|137211_137823_-	hypothetical protein	NA	NA	NA	NA
AWV05496.1\|140110_141231_-\|transposase	IS3-like element IS407 family transposase	S5WIU1	Leptospira_phage	1.2e-49	39.9
AWV05497.1\|141178_141379_-	hypothetical protein	NA	NA	NA	NA
AWV05498.1\|142078_142753_-	DNA-binding response regulator	NA	NA	NA	NA
AWV05697.1\|142742_144890_-	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
AWV05499.1\|144980_145367_-	response regulator	NA	NA	NA	NA
AWV05500.1\|145772_146126_+	DUF4148 domain-containing protein	NA	NA	NA	NA
AWV05501.1\|146349_147510_+	HoxN/HupN/NixA family nickel/cobalt transporter	NA	NA	NA	NA
AWV05502.1\|149300_149744_-	hypothetical protein	NA	NA	NA	NA
AWV05503.1\|149740_149947_-	hypothetical protein	NA	NA	NA	NA
AWV05504.1\|150002_150956_-	AraC family transcriptional regulator	A0A291LAM3	Bordetella_phage	2.2e-10	29.9
AWV05505.1\|151642_151993_+	phospholipid-binding protein	NA	NA	NA	NA
AWV05506.1\|153823_155341_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.4e-43	30.7
AWV05507.1\|156041_156344_+	hypothetical protein	NA	NA	NA	NA
AWV05508.1\|157080_157260_-	hypothetical protein	NA	NA	NA	NA
AWV05509.1\|157917_158913_-	NAD(P)H-quinone oxidoreductase	NA	NA	NA	NA
AWV05510.1\|158909_159287_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
AWV05511.1\|159300_160737_-	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
AWV05512.1\|160947_161184_-	Sec-independent protein translocase subunit TatA	NA	NA	NA	NA
AWV05513.1\|161571_163062_-	class II fumarate hydratase	NA	NA	NA	NA
AWV05514.1\|163365_163923_-	hypothetical protein	NA	NA	NA	NA
AWV05515.1\|164604_164994_+\|transposase	IS3 family transposase	NA	NA	NA	NA
AWV05516.1\|164990_165353_+	hypothetical protein	NA	NA	NA	NA
AWV05517.1\|166309_166660_+	hypothetical protein	NA	NA	NA	NA
AWV05518.1\|167030_167597_-	chloramphenicol phosphotransferase	NA	NA	NA	NA
AWV05519.1\|167695_169261_-\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	1.3e-68	33.9
AWV05520.1\|169292_169643_-	IS66 family insertion sequence hypothetical protein	S5VXZ8	Leptospira_phage	3.7e-16	38.5
AWV05698.1\|169618_170161_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
AWV05521.1\|171015_172114_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.5e-36	36.9

DBSCAN-SWA_3

178156 : 250356

Leptospira_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05523.1\|178156_179251_-\|transposase	IS5 family transposase	NA	NA	NA	NA
AWV05524.1\|179477_179681_-	hypothetical protein	NA	NA	NA	NA
AWV05525.1\|181517_181910_-	hypothetical protein	NA	NA	NA	NA
AWV05699.1\|182609_183696_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.8e-45	37.9
AWV05526.1\|186129_188973_-	fatty acyl-AMP ligase	A0A2H4PQU7	Staphylococcus_phage	5.4e-17	24.8
AWV05700.1\|189109_190681_-	AMP-dependent synthetase	A0A2H4PQU7	Staphylococcus_phage	2.6e-21	26.3
AWV05527.1\|191685_192948_+	MFS transporter	NA	NA	NA	NA
AWV05528.1\|193045_195550_-	DUF3417 domain-containing protein	NA	NA	NA	NA
AWV05701.1\|195589_197221_-	glycogen synthase GlgA	NA	NA	NA	NA
AWV05529.1\|197495_199754_+	1,4-alpha-glucan branching enzyme	NA	NA	NA	NA
AWV05530.1\|199680_203688_+	4-alpha-glucanotransferase	NA	NA	NA	NA
AWV05531.1\|203872_204100_-	hypothetical protein	NA	NA	NA	NA
AWV05702.1\|204233_204872_-	DNA-binding response regulator	NA	NA	NA	NA
AWV05532.1\|205969_207115_-	AI-2E family transporter	NA	NA	NA	NA
AWV05533.1\|207111_209817_-	ATPase	M1I547	Acanthocystis_turfacea_Chlorella_virus	2.9e-76	29.6
AWV05534.1\|211925_213161_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	4.6e-05	23.0
AWV05535.1\|215334_215763_-	hypothetical protein	NA	NA	NA	NA
AWV05536.1\|216346_217363_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
AWV05703.1\|217381_217705_-	hypothetical protein	NA	NA	NA	NA
AWV05537.1\|217872_219387_+	histidine kinase	NA	NA	NA	NA
AWV05538.1\|220303_220495_+	hypothetical protein	NA	NA	NA	NA
AWV05704.1\|220773_221112_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
AWV05539.1\|221184_222066_+	DNA-binding protein	NA	NA	NA	NA
AWV05540.1\|222629_223589_-	acetyltransferase	NA	NA	NA	NA
AWV05541.1\|223612_224620_+	ribose-phosphate pyrophosphokinase	A0A1V0SHF7	Hokovirus	1.3e-21	26.3
AWV05542.1\|225523_225940_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
AWV05543.1\|225936_226278_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZDM8	Stx2-converting_phage	1.2e-35	66.7
AWV05544.1\|226329_227880_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	6.8e-155	56.2
AWV05545.1\|229615_230071_-	hypothetical protein	NA	NA	NA	NA
AWV05546.1\|230275_230515_-	hypothetical protein	NA	NA	NA	NA
AWV05547.1\|231098_231548_-	CBS domain-containing protein	NA	NA	NA	NA
AWV05548.1\|231609_232260_-	OsmY domain-containing protein	NA	NA	NA	NA
AWV05549.1\|232332_232746_-	hypothetical protein	NA	NA	NA	NA
AWV05550.1\|233140_233356_+	hypothetical protein	NA	NA	NA	NA
AWV05551.1\|234056_234638_+	cold shock domain-containing protein	NA	NA	NA	NA
AWV05552.1\|234730_235117_+	hypothetical protein	NA	NA	NA	NA
AWV05553.1\|235239_236433_-	hypothetical protein	S5WIU1	Leptospira_phage	4.3e-40	37.1
AWV05554.1\|236453_236852_-	hypothetical protein	NA	NA	NA	NA
AWV05555.1\|237014_237947_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
AWV05705.1\|238136_238709_+	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
AWV05706.1\|238727_239477_-	short-chain dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	7.1e-17	30.8
AWV05556.1\|239585_240464_+	LysR family transcriptional regulator	NA	NA	NA	NA
AWV05557.1\|240540_240948_-	cupin	NA	NA	NA	NA
AWV05558.1\|241011_241491_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
AWV05559.1\|241791_242790_+	multidrug transporter	NA	NA	NA	NA
AWV05560.1\|242815_243328_-	peroxiredoxin	NA	NA	NA	NA
AWV05561.1\|243540_244551_-	LysR family transcriptional regulator	NA	NA	NA	NA
AWV05562.1\|244700_245582_-	RNA polymerase subunit sigma-24	NA	NA	NA	NA
AWV05563.1\|246518_247654_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.6e-10	25.7
AWV05564.1\|248002_249133_-\|transposase	IS110 family transposase	NA	NA	NA	NA
AWV05565.1\|249296_250356_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.0e-49	39.9

DBSCAN-SWA_4

268636 : 338670

Leptospira_phage(14.29%)

transposase,integrase

attL 264453:264468|attR 340721:340736

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
264453:264468	attL	NA	NA	NA	NA
AWV05579.1\|268636_269659_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	3.8e-05	28.0
AWV05580.1\|270292_271392_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	5.9e-36	36.5
AWV05581.1\|271410_272498_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.2e-44	37.5
AWV05582.1\|273151_274171_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	2.9e-45	35.6
AWV05583.1\|274773_274965_-	hypothetical protein	NA	NA	NA	NA
AWV05584.1\|275356_276211_-	peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
AWV05585.1\|276301_278089_-	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
AWV05586.1\|278213_280298_-	filamentous hemagglutinin	A0A0R6PJK4	Moraxella_phage	1.8e-17	29.8
AWV05711.1\|280870_289282_-	filamentous hemagglutinin	NA	NA	NA	NA
AWV05587.1\|290298_290598_+	H-NS histone family protein	F8TUP5	EBPR_podovirus	2.4e-08	38.2
AWV05588.1\|290699_291092_+	hypothetical protein	NA	NA	NA	NA
AWV05589.1\|291241_292171_+\|integrase	site-specific integrase	NA	NA	NA	NA
AWV05590.1\|292241_292721_+	hypothetical protein	NA	NA	NA	NA
AWV05712.1\|292852_294655_-	hypothetical protein	NA	NA	NA	NA
AWV05591.1\|294726_295290_-	endonuclease	A0A1B2LRT6	Wolbachia_phage	8.2e-18	30.7
AWV05592.1\|295377_295707_-	hypothetical protein	NA	NA	NA	NA
AWV05593.1\|295844_296039_-	hypothetical protein	NA	NA	NA	NA
AWV05713.1\|296950_297760_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	9.0e-34	34.2
AWV05714.1\|297749_299267_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.3e-17	32.1
AWV05594.1\|300051_300768_-	type IV secretion system protein	NA	NA	NA	NA
AWV05595.1\|301169_301745_+	hypothetical protein	NA	NA	NA	NA
AWV05596.1\|302831_303713_+	replication initiation protein	E5FFJ0	Burkholderia_phage	2.6e-34	38.1
AWV05597.1\|303829_304861_-	chromosome partitioning protein ParB	NA	NA	NA	NA
AWV05598.1\|304857_305517_-	ParA family protein	A2I303	Vibrio_virus	6.2e-17	32.9
AWV05599.1\|305810_306056_+	hypothetical protein	NA	NA	NA	NA
AWV05600.1\|309401_310058_+	hypothetical protein	NA	NA	NA	NA
AWV05601.1\|310469_311690_-\|integrase	integrase	NA	NA	NA	NA
AWV05602.1\|312423_312681_+	hypothetical protein	NA	NA	NA	NA
AWV05603.1\|312680_313952_+	hypothetical protein	NA	NA	NA	NA
AWV05604.1\|314022_314805_+	hypothetical protein	NA	NA	NA	NA
AWV05605.1\|314870_315539_+	hypothetical protein	NA	NA	NA	NA
AWV05606.1\|315540_317856_+\|integrase	integrase	A0A2D1G8E2	Mycobacterium_phage	4.2e-07	31.8
AWV05607.1\|317909_318512_+	hypothetical protein	NA	NA	NA	NA
AWV05715.1\|320317_320773_-	hypothetical protein	NA	NA	NA	NA
AWV05716.1\|321076_321448_+	hypothetical protein	NA	NA	NA	NA
AWV05608.1\|321455_321743_-	PAAR domain-containing protein	NA	NA	NA	NA
AWV05717.1\|321756_322713_-	hypothetical protein	NA	NA	NA	NA
AWV05609.1\|322817_324488_-	hypothetical protein	NA	NA	NA	NA
AWV05610.1\|324735_327399_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	3.5e-42	26.1
AWV05611.1\|327809_330959_-	error-prone DNA polymerase	A0A0K1Y9G6	Streptomyces_phage	1.4e-93	27.4
AWV05718.1\|330964_332425_-	DNA polymerase Y family protein	NA	NA	NA	NA
AWV05612.1\|332363_333080_-	translesion DNA synthesis-associated protein ImuA	NA	NA	NA	NA
AWV05613.1\|333627_334812_+\|integrase	site-specific integrase	NA	NA	NA	NA
AWV05614.1\|336717_338670_+\|integrase	integrase	NA	NA	NA	NA
340721:340736	attR	NA	NA	NA	NA

DBSCAN-SWA_5

348252 : 410603

Bacillus_phage(28.57%)

transposase,integrase

attL 355246:355262|attR 404730:404746

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV05622.1\|348252_348924_+\|integrase	site-specific integrase	A0A1W6DWU1	Sphingobium_phage	1.1e-11	28.6
AWV05623.1\|348979_349183_+	XRE family transcriptional regulator	NA	NA	NA	NA
AWV05721.1\|349266_349542_+	YkgJ family cysteine cluster protein	NA	NA	NA	NA
AWV05624.1\|349847_350114_+	hypothetical protein	NA	NA	NA	NA
AWV05625.1\|350139_350652_+	hypothetical protein	NA	NA	NA	NA
AWV05626.1\|350673_351483_+	hypothetical protein	NA	NA	NA	NA
AWV05627.1\|351768_352047_+	HU family DNA-binding protein	A4JWM7	Burkholderia_virus	2.4e-18	56.2
AWV05628.1\|352166_353012_+	hypothetical protein	NA	NA	NA	NA
AWV05629.1\|353083_353854_+	hypothetical protein	NA	NA	NA	NA
AWV05630.1\|353870_354119_+	hypothetical protein	NA	NA	NA	NA
AWV05631.1\|354126_354369_+	hypothetical protein	NA	NA	NA	NA
AWV05632.1\|354385_354607_+	hypothetical protein	NA	NA	NA	NA
AWV05633.1\|354653_354917_-	hypothetical protein	NA	NA	NA	NA
AWV05634.1\|354983_355616_+	hypothetical protein	NA	NA	NA	NA
355246:355262	attL	NA	NA	NA	NA
AWV05635.1\|355615_357601_+\|integrase	integrase	NA	NA	NA	NA
AWV05722.1\|357627_358605_+	ATP-binding protein	NA	NA	NA	NA
AWV05723.1\|358672_359224_+	hypothetical protein	NA	NA	NA	NA
AWV05636.1\|359575_360595_+\|transposase	IS110 family transposase	NA	NA	NA	NA
AWV05637.1\|361182_361899_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AWV05638.1\|361987_362722_-	3-alpha-hydroxysteroid dehydrogenase	W8CYX9	Bacillus_phage	5.0e-07	33.6
AWV05639.1\|362805_363294_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
AWV05640.1\|363396_364116_-	oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.9e-14	30.4
AWV05641.1\|364152_364893_-	short-chain dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	2.9e-15	30.0
AWV05642.1\|364968_366645_-	FAD-binding dehydrogenase	A0A2P0ZL82	Lactobacillus_phage	2.9e-18	24.3
AWV05643.1\|367089_368310_-\|transposase	ISL3 family transposase	A9YX10	Burkholderia_phage	7.5e-226	93.1
AWV05644.1\|368204_369488_-	benzaldehyde dehydrogenase	NA	NA	NA	NA
AWV05645.1\|369685_369973_+	hypothetical protein	NA	NA	NA	NA
AWV05646.1\|370230_370998_+	short-chain dehydrogenase	NA	NA	NA	NA
AWV05647.1\|371088_371829_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AWV05648.1\|373175_374039_+	VOC family protein	NA	NA	NA	NA
AWV05649.1\|374061_375747_+	(2,3-dihydroxybenzoyl)adenylate synthase	NA	NA	NA	NA
AWV05650.1\|375748_376531_+	Asp/Glu racemase	NA	NA	NA	NA
AWV05651.1\|376532_377030_+	thioesterase	NA	NA	NA	NA
AWV05652.1\|377026_378193_+	monooxygenase	NA	NA	NA	NA
AWV05653.1\|378304_379651_+	aromatic acid/H+ symport family MFS transporter	NA	NA	NA	NA
AWV05654.1\|379616_380612_-	hypothetical protein	NA	NA	NA	NA
AWV05655.1\|380608_381838_-	MFS transporter	NA	NA	NA	NA
AWV05656.1\|382172_383075_+	LysR family transcriptional regulator	NA	NA	NA	NA
AWV05657.1\|383106_383583_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
AWV05658.1\|383603_384434_-	short-chain dehydrogenase/reductase	W8CYX9	Bacillus_phage	7.9e-09	38.4
AWV05659.1\|384430_385330_-	epimerase	NA	NA	NA	NA
AWV05660.1\|385414_386038_-	hypothetical protein	NA	NA	NA	NA
AWV05661.1\|386736_388209_-	benzaldehyde dehydrogenase	NA	NA	NA	NA
AWV05724.1\|388303_389908_-	dehydrogenase	A0A1V0S9M4	Catovirus	7.3e-35	27.2
AWV05662.1\|390060_390963_-	LysR family transcriptional regulator	NA	NA	NA	NA
AWV05663.1\|391272_392838_-\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	6.4e-68	33.8
AWV05664.1\|392869_393220_-	IS66 family insertion sequence hypothetical protein	S5VXZ8	Leptospira_phage	3.7e-16	38.5
AWV05665.1\|393195_393738_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
AWV05666.1\|393797_394148_-	hypothetical protein	NA	NA	NA	NA
AWV05667.1\|396417_398583_+	dextransucrase	NA	NA	NA	NA
AWV05668.1\|399557_399854_-	DUF4148 domain-containing protein	NA	NA	NA	NA
AWV05669.1\|400071_400746_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	3.1e-27	32.4
AWV05670.1\|400757_402149_+	histidine kinase	W8CYF6	Bacillus_phage	1.1e-15	24.1
AWV05671.1\|402168_402834_+	DNA-binding response regulator	NA	NA	NA	NA
AWV05672.1\|402892_403156_-	DUF4148 domain-containing protein	NA	NA	NA	NA
AWV05673.1\|404675_405851_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
404730:404746	attR	NA	NA	NA	NA
AWV05674.1\|409232_409364_+	hypothetical protein	NA	NA	NA	NA
AWV05675.1\|409467_410603_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	5.2e-11	25.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage