CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP021963	Citrobacter youngae strain L6 chromosome, complete genome	3 crisprs	cas3,WYL,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,csa3,DEDDh,DinG,RT	0	13	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP021963_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021963_1

1010000-1011310

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

21 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of CP021963_1

>merge|CP021963|1|1010000-1011310|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGTGTTTATTTGTCGTTTCTGGTTTCTAGATGTGGTGTTCCCCGCGCCAGCGGGGATAAACCGAGAGGAAGAATGAAAAAGGTGATCACCCCGCGGTGTTCCCCGCGCCAGCGGGGATAAACCGCGCCGCAGATCCCTGAGCTGCTGTTTGACCTGCGTGTTCCCCGCGCCAGCGGGGATAAACCGAATGCAACGCCCTGAGCGCCGACGTAAGCCGCGTGTTCCCCGCGCCAGCGGGGATAAACCGACGACGACCCGGCGCAGACCGCCATCGACCGGGTGTTCCCCGCGCCAGCGGGGATAAACCGCACATAGTTAACCGTGTCCCAGTCGGACAAGTGTGTTCCCCGCGCCAGCGGGGATAAACCGGTGGAATGGCGAGAAGGCGCAGGCCTTTATGCGTGTTCCCCGCGCCAGCGGGGATAAACCGAGGTCCAGGAGAGCGCCATGCGTATCACGACAGTGTTCCCCGCGCCAGCGGGGATAAACCGCAAATGCGGGATGGATGGAGAGTTAACAGGACGTGTTCCCCGCGCCAGCGGGGATAAACCGCAATCAAGACCTAGACAATCTTGATTATACGGGTGTTCCCCGCGCCAGCGGGGATAAACCGAGGTGCAATTGCGTGAGGCTCGGGAGCGCGTTGTGTTCCCCGCGCCAGCGGGGATAAACCGACAATGTTGCGTCTAATTCTCATTAAATAAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGGTGATCGGCCTGTCCGGTACACCATTCACTAAGTGTTCCCCGCGCCAGCGGGGATAAACCGATACTGGCCGTTGCCCCGGGCATCGAGCTTAAGTGTTCCCCGCGCCAGCGGGGATAAACCGCGCTGGAGCAGGACGCAGCGGACGGCACATTTGTGTTCCCCGCGCCAGCGGGGATAAACCGACGGCATGAAAATGCTGATGGGCCAAATGGCGGTGTTCCCCGCGCCAGCGGGGATAAACCGTGGAAGCGATCGGACCCGGCTCCTGCGCAGCAGTGTTCCCCGCGCCAGCGGGGATAAACCGCTGTCCCTTTGTTTTACCAGAGCGGTCCAGTAGTGTTCCCCGCGCCAGCGGGGATAAACCGACTCATCAATACTGCAAAAACTCGGTGTATCTGTGTTCCCCGCGCCAGCGGGGATAAACCGGATACGCCTGAATTCGACGTTATCTCGCCAACGTGTTCCCCGCACCAGCGGGGATAAACCGAATTTATCCGGGACTACAACATATCTCTTTATGTGTTCCCCGCGCCAGCGGGGATAAAGTC

>CP021963|1|1|1010000-1011249|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGTTTATTTGTCGTTTCTGGTTTCTAGATGTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGAGGAAGAATGAAAAAGGTGATCACCCCGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCCGCAGATCCCTGAGCTGCTGTTTGACCTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATGCAACGCCCTGAGCGCCGACGTAAGCCGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGACGACCCGGCGCAGACCGCCATCGACCGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CACATAGTTAACCGTGTCCCAGTCGGACAAGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTGGAATGGCGAGAAGGCGCAGGCCTTTATGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGGTCCAGGAGAGCGCCATGCGTATCACGACA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAAATGCGGGATGGATGGAGAGTTAACAGGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAATCAAGACCTAGACAATCTTGATTATACGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGGTGCAATTGCGTGAGGCTCGGGAGCGCGTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACAATGTTGCGTCTAATTCTCATTAAATAAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTGATCGGCCTGTCCGGTACACCATTCACTAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATACTGGCCGTTGCCCCGGGCATCGAGCTTAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCTGGAGCAGGACGCAGCGGACGGCACATTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGCATGAAAATGCTGATGGGCCAAATGGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGGAAGCGATCGGACCCGGCTCCTGCGCAGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTGTCCCTTTGTTTTACCAGAGCGGTCCAGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACTCATCAATACTGCAAAAACTCGGTGTATCT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GATACGCCTGAATTCGACGTTATCTCGCCAAC
GTGTTCCCCGCACCAGCGGGGATAAACCG

>CP021963|1|1|1010000-1011310|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGTTTATTTGTCGTTTCTGGTTTCTAGATGTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGAGGAAGAATGAAAAAGGTGATCACCCCGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCCGCAGATCCCTGAGCTGCTGTTTGACCTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATGCAACGCCCTGAGCGCCGACGTAAGCCGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGACGACCCGGCGCAGACCGCCATCGACCGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CACATAGTTAACCGTGTCCCAGTCGGACAAGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTGGAATGGCGAGAAGGCGCAGGCCTTTATGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGGTCCAGGAGAGCGCCATGCGTATCACGACA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAAATGCGGGATGGATGGAGAGTTAACAGGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAATCAAGACCTAGACAATCTTGATTATACGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGGTGCAATTGCGTGAGGCTCGGGAGCGCGTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACAATGTTGCGTCTAATTCTCATTAAATAAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTGATCGGCCTGTCCGGTACACCATTCACTAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATACTGGCCGTTGCCCCGGGCATCGAGCTTAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCTGGAGCAGGACGCAGCGGACGGCACATTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGCATGAAAATGCTGATGGGCCAAATGGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGGAAGCGATCGGACCCGGCTCCTGCGCAGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTGTCCCTTTGTTTTACCAGAGCGGTCCAGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACTCATCAATACTGCAAAAACTCGGTGTATCT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GATACGCCTGAATTCGACGTTATCTCGCCAAC
GTGTTCCCCGCACCAGCGGGGATAAACCG	AATTTATCCGGGACTACAACATATCTCTTTAT
GTGTTCCCCGCGCCAGCGGGGATAAAGTC

>CP021963|1|1|1010000-1011310|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGTTTATTTGTCGTTTCTGGTTTCTAGATGTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGAGGAAGAATGAAAAAGGTGATCACCCCGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCCGCAGATCCCTGAGCTGCTGTTTGACCTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATGCAACGCCCTGAGCGCCGACGTAAGCCGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGACGACCCGGCGCAGACCGCCATCGACCGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CACATAGTTAACCGTGTCCCAGTCGGACAAGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTGGAATGGCGAGAAGGCGCAGGCCTTTATGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGGTCCAGGAGAGCGCCATGCGTATCACGACA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAAATGCGGGATGGATGGAGAGTTAACAGGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAATCAAGACCTAGACAATCTTGATTATACGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGGTGCAATTGCGTGAGGCTCGGGAGCGCGTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACAATGTTGCGTCTAATTCTCATTAAATAAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTGATCGGCCTGTCCGGTACACCATTCACTAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATACTGGCCGTTGCCCCGGGCATCGAGCTTAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCTGGAGCAGGACGCAGCGGACGGCACATTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGCATGAAAATGCTGATGGGCCAAATGGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGGAAGCGATCGGACCCGGCTCCTGCGCAGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTGTCCCTTTGTTTTACCAGAGCGGTCCAGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACTCATCAATACTGCAAAAACTCGGTGTATCT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GATACGCCTGAATTCGACGTTATCTCGCCAAC
GTGTTCCCCGCACCAGCGGGGATAAACCG	AATTTATCCGGGACTACAACATATCTCTTTAT
GTGTTCCCCGCGCCAGCGGGGATAAAGTC

Protein	Signature genes	Signature genes Name	Protein_function
CP021963.1\|AWV25630.1\|1004028_1005564_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
CP021963.1\|AWV25637.1\|1011401_1012448_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
CP021963.1\|AWV25643.1\|1016568_1017264_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
CP021963.1\|AWV25635.1\|1008701_1009619_+\|subtype-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
CP021963.1\|AWV25628.1\|1000194_1000929_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
CP021963.1\|AWV25641.1\|1015700_1016024_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371891
CP021963.1\|AWV25638.1\|1012702_1013611_+\|sulfate-adenylyltransferase-small-subunit	unknown	unknown	gnl\|CDD\|235375
CP021963.1\|AWV25631.1\|1005579_1006182_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|274193
CP021963.1\|AWV25640.1\|1015047_1015653_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
CP021963.1\|AWV25632.1\|1006204_1007263_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
CP021963.1\|AWV25646.1\|1018825_1019587_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
CP021963.1\|AWV25633.1\|1007272_1007998_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
CP021963.1\|AWV25642.1\|1016238_1016550_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
CP021963.1\|AWV25644.1\|1017319_1017799_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
CP021963.1\|AWV25639.1\|1013620_1015048_+\|sulfate-adenylyltransferase	unknown	unknown	gnl\|CDD\|235349
CP021963.1\|AWV25629.1\|1000973_1003673_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|182031
CP021963.1\|AWV25645.1\|1017795_1018845_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
CP021963.1\|AWV25634.1\|1007997_1008702_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|187795
CP021963.1\|AWV25636.1\|1009621_1009915_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
CP021963.1\|AWV29132.1\|1000067_1000250_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP021963.1\|AWV25630.1\|1004028_1005564_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	2.68012e-178
CP021963.1\|AWV25637.1\|1011401_1012448_-\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
CP021963.1\|AWV25635.1\|1008701_1009619_+\|subtype-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	3.91432e-158
CP021963.1\|AWV25628.1\|1000194_1000929_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	4.28156e-138
CP021963.1\|AWV25641.1\|1015700_1016024_+\|hypothetical-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	2.18311e-46
CP021963.1\|AWV25634.1\|1007997_1008702_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|187795	cd09664, Cas6_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas6e. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6e is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-E subtype; Homologous to Cas6 (RAMP superfamily protein); Possesses double RRM/ferredoxin fold; also known as Cse3 family.	3.71828e-73
CP021963.1\|AWV25631.1\|1005579_1006182_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|274193	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It was designated Cse2 originally, and renamed CasB based on its characterization in the CASCADE complex.	7.52081e-35
CP021963.1\|AWV25640.1\|1015047_1015653_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	3.06027e-149
CP021963.1\|AWV25632.1\|1006204_1007263_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.94667e-119
CP021963.1\|AWV25646.1\|1018825_1019587_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.70412e-149
CP021963.1\|AWV25633.1\|1007272_1007998_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.1162e-46
CP021963.1\|AWV25642.1\|1016238_1016550_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	3.92359e-64
CP021963.1\|AWV25644.1\|1017319_1017799_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.67718e-103
CP021963.1\|AWV25639.1\|1013620_1015048_+\|sulfate-adenylyltransferase	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
CP021963.1\|AWV25629.1\|1000973_1003673_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	7.52701e-149
CP021963.1\|AWV25645.1\|1017795_1018845_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
CP021963.1\|AWV25638.1\|1012702_1013611_+\|sulfate-adenylyltransferase-small-subunit	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
CP021963.1\|AWV25636.1\|1009621_1009915_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	4.77025e-62
CP021963.1\|AWV25643.1\|1016568_1017264_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	4.81053e-120

>CP021963.1|AWV25636.1|1009621_1009915_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSVLVVVTENVPPRLRGRLAVWLLEIRAGVYVGNVSTKIREMIWQQVSVLAEEGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVLNQ
>CP021963.1|AWV25635.1|1008701_1009619_+|subtype-I-E-CRISPR-associated-endonuclease-Cas1
MAWLPLNPIPLKDRVSMIFLQYGQIDVIDGTFVLIDKTGVRTHIPVGSVACIMLEPGTRVSHAAVRLAATVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPSRRSVEQLRGIEGSRVRATYALLAKQYGVKWQGRRYDPKDWEKGDVINQCISSATACLYGVTEAATLAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIAKRNPTDPDREVRLACRDIFRSGKTLAKLIPLIEDVLAAGEIQPPLPPEDSQPIAIPLPVSVGDSGHRIN
>CP021963.1|AWV25634.1|1007997_1008702_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRIQLRFNQLRPEMLEKWHSARPYASHQWLWQLFPEQESRQFLFREEAHGGFFMLSAIPPLAQHSLFLVETKAFNPQLTNGFMLDFQLRANPVITRNGKRSDVMMDAKFQAKTQGVAQEQWWELQQQAAQAWLERQGQQHGFRLLEEETDDFAQWAGAEQSEMQARCGCVQAYQQHRFVRNDREESIAFSSVDFSGTLCITDASRFEQALYSGLGKSKALGCGMLMVKRKR
>CP021963.1|AWV25633.1|1007272_1007998_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MKEYLVFQLYAPLASWGEEASGEIRHSATVPTRSALLGLLAAALGIRRDEEERLNSFNQHYHLAVHALASQDRWLRDYHTVSAPRENKKYRYYTRRDELTLAPDEVGTLISQREYRCDGYWHVAISVTPDAPHTLSEMRAALLTPHFPLYLGRKSCPLALPLAPRLMTGTLKEIFTQAVEELSAAELSGFTLREGVCYWDDPDEASLVWQQKQHSNNQPVSRQRWQFGGYTRFYGPLQERT
>CP021963.1|AWV25632.1|1006204_1007263_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTSFIQLHLLTAYAPANLNRDESGRPKTAYMGGVERLRVSSQSLKRAWRVSETFEGAMDGFMGKRTRRIGVDYVYRPMTAAGVIGKTAKSAAEKIAAQFGKLKSDKNAPEEKNLEIEQIVHVSNHEISLIKQLVDTLIAEKREPSDEEVKLLRKEQRSVDMALFGRMLASSPEFNVEAACQVSHALGVSAVTVESDFFTAVDDLNNKEEDAGSGHMGEQGFASALFYTYVCISRDLLVENLGGNEDLAKRAIAALTETALTVSPTGKQNSFASRAYATYALAEIGQKQPRSLAAAFFQPVRDTDQIPAAIARLTQQRASFDSVYGNCADDYRELNVQDGTGSLAELLAFVSQ
>CP021963.1|AWV25631.1|1005579_1006182_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MLNSNTAALCRILNSDAQKALLDWFATLSERYERKDDKRINGRAWRAELKRMAPPYGVMMCEGYDALRQALLKHMPLQPLDEMALALFVSVAAHIKSHKEKASFAAQLGEKLKGSTPCVSALRFERLQKASDPETFCLLLIQAVKIRGTEGVNVLSLADGIFLWMEEWQRRENHQPEPANPFERNRTRWANEYLSMSRGK
>CP021963.1|AWV25630.1|1004028_1005564_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDLTREKWLPVIFSSGEKKRISLSELLDNNIQDLAYPRADFQGAAWQMLIGILQCTVAPEDKEEWADIWHDGIEFEQWEKALTTISLALQFGEQKPSFLQSFDPLDSEYGSIAGLLVDAPGGNTLKLNKDHFVKRGNVEKICPHCAAIALFAIQANSPAGGAGYRVGMRGGGPLTTLVVPQEEDKYPLWKKLWLNVLPQEAKPTVAQYPLIFPWLAPTKTSEKAGNVVTPENSHPLQAYWGMPRRIELDFSQTMAGICDLCGEHHESLLLQMRSKNYGVQYDSWLHPFSPYRQVLKDPSAPWLALKGQPGGLSYKDWLGLMLNREDKFNKMQPAKVVRAAGQRNNMSLWCFAFDMENAKARCWYQNRIPLISVSHEEQFLAALNAVLVLASEALSLLRNALKSAKFETPKEAKMDFSMVDIAFWQETEPAFRVLQEALVADPLRQNPLTHRAVRQWEQELARYLFHVFDRDALTNPDCPDDILLRQLTARQDFASSYRKHKARKDVLALVE
>CP021963.1|AWV25629.1|1000973_1003673_-|CRISPR-associated-helicase/endonuclease-Cas3
MTQIENLDYLRYWGKTNKSTKNTINNYHLLAYHCLDVAACGYYIIENNIFDSKDILQKCGITGTDAENWLIWFLASHDIGKFARGFQRYAEFPDSPLFPPVSGISAFERHDSLGFYLWGKLFEAWCSGSNEIIAGIESENRARFESPLNTWMLISTGHHGIPPETMKNRSSLAFADEDIVAATHYLEALSQLFPFTIPQEWKTKAGRKCLKQHSWFFAGLVTLADWMGSDETQFPLLSQPMPLVDYWPLACEKAQQAILKMPPLSQHSHYQSHQALFPFIHTLTPLQERATTLDISAPGPQLVILEDVTGAGKTEAALILTPRLMSANKGHGLYVGLPTMATANAMYKRLAAAYHALFTDDSRPSLILAHGGREMTDAFRQSIWQPTENMVDDYARDDGNASTECHTWFADSRKKALLAEVGVGTLDQLLMAVMPFRHQSLRLLGMRDKILLLDEVHAYDGYMVKLLEGLLRFHAAQGGSAIILSATLPAALREKLLHAFNDGADFTATETNEDAGYPWLSHLSSSGLLEQPLDTRPEVQRTVTIKWIQQRQQALDIIYRVVAAGQCVCWIRNTVDDARDVYQQLLHEGMLPEQDLLLFHSRFAFTDRIDIENKTLSWFGNNAPVSERRGKVLIATQVVEQSLDLDFDWMISDLAPIDLLIQRAGRLQRHIRDADGQRKPTLPDGRQPPVLHILVPEWQEQAEEGWLGQGLKGTGFVYADHACLWRTQAVLRQHGEIRMPENARALVDGVYKQEIAAPAGLQTLSDIAFGKVLSQRSVAAQNLLRHDLGYDREASDFLWDKDREFSTRLGEESVDVYLAWQNEEGEFHPVVDEGDFRWEMSRLSVRLSWWRKQSGDFLLPNDEQLELFRKKQHRPAAQMILVSPEGEAGYYNKRTGLGN
>CP021963.1|AWV25628.1|1000194_1000929_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVERVMALAQTNDQLEKLSAEDRVAWALENLPGEYVLSSSFGIQAAVSLHLVNQVRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLQVYRAKESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALQELNAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>CP021963.1|AWV29132.1|1000067_1000250_-|hypothetical-protein
MTRSTFGSSFNALRSSLDISSSLFALPDGASLIRPTDSADPISQFHIIPRNPGRDRAPGE
>CP021963.1|AWV25637.1|1011401_1012448_-|aminopeptidase
MFSALRHLTTALALGACFILPAQATSSKPGDIANTQARYIATFFPGRVTGSPAEMLSADYIRQQFQQMGYSSDIRTFNSRYVYTAKDNRKNWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAAQSDADSDANLGGLTLQGIDDNAAGVGVMLELAEKLKNVPTQYGIRFIATSGEEEGKLGAENILKRMSAAEKKNTLLVINLDNLIVGDKLYFNSGKKTPEAVRKLTRDRALAIAHSRGIVASTNPGLNKDYPKGTGCCNDAEVFDNAGIAVLSVEATNWNLGKKDGYQQRAKSASFPAGNSWHDVRLDNQQHIDKALPGRIEHRSRDVVRIMLPLVKELAKAGKNS
>CP021963.1|AWV25638.1|1012702_1013611_+|sulfate-adenylyltransferase-small-subunit
MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMMYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFSEMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>CP021963.1|AWV25639.1|1013620_1015048_+|sulfate-adenylyltransferase
MNTTLAQQIANEGGVEAWMVAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDFSEETFNRIREDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSASMPWYSGPTLLEVLETVEIQRIVDTQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGQRVKVLPSGVESSVARIVTFDGDLQEAHAGEAITLVLKDEIDISRGDLLLDAGETLPTVQSAAVDVVWMAEQPLSPGQSYDIKVAGKKTRARVDSVQYQVDINNLTQRDVEALPLNGIGLVNLTFDEPLVLDTYQQNPVTGGLIIIDRLTNVTVGAGLVREPIVQELATASQFSAFELELNALVRRHFPHWGARDLLGGK
>CP021963.1|AWV25640.1|1015047_1015653_+|adenylyl-sulfate-kinase
MALHDENVVWHAHPVTPQQREQRHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVDAGLVVLTAFISPHRAERKMVRERVGEGRFIEVFVDTPLATCEARDPKGLYKKARAGELRNFTGIDSVYEAPESPEIHLDGEQLVTNLVPQLLDLLRQEDIIRS
>CP021963.1|AWV25641.1|1015700_1016024_+|hypothetical-protein
MRNSHNITITESDTFAADDETTWSLPGAVVGFVAWLLALGFPCLMYGPNTLFFFLYTWPFFLALLPVAIVAGIALHSLLKGRLLLSIACTLLVVGAMFGALFLWLLG
>CP021963.1|AWV25642.1|1016238_1016550_+|cell-division-protein-FtsB
MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAQTAGQNNR
>CP021963.1|AWV25643.1|1016568_1017264_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MAATLMDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVDALLAHPRVTRVVIAISPGDSRFAQLPLAAHPQITVVDGGNERADSVLAGLQAAGEASWVLVHDAARPCLHQEDLSRLLAISETSRIGGILAAPVRDTMKRAEPGRTDIAHTVDRTDLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPLLVEGRADNIKVTRPEDLALAEFYLTRTI
>CP021963.1|AWV25644.1|1017319_1017799_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGVGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>CP021963.1|AWV25645.1|1017795_1018845_+|tRNA-pseudouridine(13)-synthase-TruD
MTAFEDLTYLHGKPQGHGVLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGNAMPDLSKFELEGCKVLEYARHKRKLRLGALKGNEFTLVLREVSQRNDVEARLQAISERGVPNYFGAQRFGIGGSNLQGALRWAQSDAPVRDRNKRSFWLSAARSALFNQIVSERLKKTDFNQVVDGDALQLSGRGSWFVATQEEQTELQRRVDDKELMITAALPGSGEWGTQRDALAFEEAAIADETALQSLLLREKVDASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAYIAE
>CP021963.1|AWV25646.1|1018825_1019587_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTYENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCRILRALSREPLRTGRILNINVPDLPLDQIKGIRVTRCGSRHPADQVIPQQDPRGNTLYWIGPPGEKCDAGPDTDFAAVDEGYVSITPLHVDLTAYGAHEVVSDWLDSVGADTQW

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Crispr_ID: CP021963_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021963_2

2815835-2815958

Orphan

Consensus_repeat	Method
TAGGCCTGATAAGCACAGCGCATCAGGCAGTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP021963_2

>merge|CP021963|2|2815835-2815958|CRISPRCasFinder
TAGGCCTGATAAGCACAGCGCATCAGGCAGTTACACGTCCCCATGCCGGATGCGGCTAACGCCTTATCCGGCCTACAAACTACACGCAGCCATAGGCCTGATAAGCACAGCGCGTCAGGCAGTT

>CP021963|2|2|2815835-2815958|CRISPRCasFinder
TAGGCCTGATAAGCACAGCGCATCAGGCAGTT	ACACGTCCCCATGCCGGATGCGGCTAACGCCTTATCCGGCCTACAAACTACACGCAGCCA
TAGGCCTGATAAGCACAGCGCGTCAGGCAGTT

Protein	Signature genes	Signature genes Name	Protein_function
CP021963.1\|AWV29200.1\|2812352_2812697_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|236895
CP021963.1\|AWV27234.1\|2812742_2813018_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225681
CP021963.1\|AWV27242.1\|2819637_2821572_+\|serine-protein-kinase-PrkA	unknown	unknown	gnl\|CDD\|185352
CP021963.1\|AWV27237.1\|2814883_2815768_+\|D-hexose-6-phosphate-mutarotase	unknown	unknown	gnl\|CDD\|223748
CP021963.1\|AWV27231.1\|2808226_2809606_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|273327
CP021963.1\|AWV27244.1\|2823071_2823842_-\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
CP021963.1\|AWV27240.1\|2817634_2817877_-\|hypothetical-protein	unknown	unknown	unknown
CP021963.1\|AWV27229.1\|2806304_2807141_-\|ketose-bisphosphate-aldolase	unknown	unknown	gnl\|CDD\|272938
CP021963.1\|AWV27239.1\|2817273_2817624_-\|hypothetical-protein	unknown	unknown	unknown
CP021963.1\|AWV27245.1\|2824006_2825497_+\|diguanylate-cylase	unknown	unknown	gnl\|CDD\|319173
CP021963.1\|AWV27247.1\|2826182_2826629_+\|DUF441-family-protein	unknown	unknown	gnl\|CDD\|225334
CP021963.1\|AWV27246.1\|2825541_2826045_+\|YbaK/prolyl-tRNA-synthetase-associated-domain-containing-protein	unknown	unknown	gnl\|CDD\|239828
CP021963.1\|AWV27233.1\|2811005_2812259_+\|chitinase	unknown	unknown	gnl\|CDD\|119365
CP021963.1\|AWV27235.1\|2813060_2813474_-\|peptide-methionine-(R)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|234692
CP021963.1\|AWV27232.1\|2809632_2810709_-\|alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|176219
CP021963.1\|AWV27243.1\|2821693_2822977_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377280
CP021963.1\|AWV27241.1\|2818457_2819204_-\|MipA/OmpV-family-protein	unknown	unknown	gnl\|CDD\|226236
CP021963.1\|AWV27236.1\|2813815_2814811_+\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|185323
CP021963.1\|AWV27238.1\|2816241_2817093_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|381364
CP021963.1\|AWV27230.1\|2807165_2808209_-\|alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|176188

Protein	Function_ID	Function_description	E-value
CP021963.1\|AWV29200.1\|2812352_2812697_+\|HNH-endonuclease	gnl\|CDD\|236895	PRK11295, PRK11295, HNH nuclease family protein.	2.02704e-82
CP021963.1\|AWV27234.1\|2812742_2813018_-\|hypothetical-protein	gnl\|CDD\|225681	COG3139, COG3139, Uncharacterized protein conserved in bacteria [Function unknown].	8.55841e-47
CP021963.1\|AWV27242.1\|2819637_2821572_+\|serine-protein-kinase-PrkA	gnl\|CDD\|185352	PRK15455, PRK15455, PrkA family serine protein kinase; Provisional.	0
CP021963.1\|AWV27237.1\|2814883_2815768_+\|D-hexose-6-phosphate-mutarotase	gnl\|CDD\|223748	COG0676, COG0676, Uncharacterized enzymes related to aldose 1-epimerase [Carbohydrate transport and metabolism].	1.4595e-148
CP021963.1\|AWV27231.1\|2808226_2809606_-\|MFS-transporter	gnl\|CDD\|273327	TIGR00895, transport_protein, benzoate transport. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.27286e-32
CP021963.1\|AWV27229.1\|2806304_2807141_-\|ketose-bisphosphate-aldolase	gnl\|CDD\|272938	TIGR00167, Fructose-bisphosphate_aldolase, ketose-bisphosphate aldolase. This model is under revision. Proteins found by this model include fructose-bisphosphate and tagatose-bisphosphate aldolase. [Energy metabolism, Glycolysis/gluconeogenesis].	3.4651e-127
CP021963.1\|AWV27244.1\|2823071_2823842_-\|SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.76285e-23
CP021963.1\|AWV27245.1\|2824006_2825497_+\|diguanylate-cylase	gnl\|CDD\|319173	pfam17155, GAPES1, Gammaproteobacterial periplasmic sensor domain. GAPES1 (GAmmaproteobacterial PEriplasmic Sensor) domain is a periplasmic sensor domain found in diguanylate cyclases and methyl-accepting chemotaxis proteins, including the diguanylate cyclase DgcJ (YeaJ) that regulates biofilm formation and motility in Escherichia coli and (Hengge R. et al. ((2015)) 'A systematic naming system for GGDEF- and EAL-containing c-di-GMP turnover proteins in Escherichia coli K-12'. J.Bacteriol., in preparation).	1.78278e-142
CP021963.1\|AWV27247.1\|2826182_2826629_+\|DUF441-family-protein	gnl\|CDD\|225334	COG2707, COG2707, Predicted membrane protein [Function unknown].	4.65306e-55
CP021963.1\|AWV27246.1\|2825541_2826045_+\|YbaK/prolyl-tRNA-synthetase-associated-domain-containing-protein	gnl\|CDD\|239828	cd04336, YeaK, YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function. The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, and ProX. The primary function of INS is to hydrolyze mischarged cysteinyl-tRNA(Pro)'s, thus helping ensure the fidelity of translation. Organisms whose ProRS lacks the INS domain express a single-domain INS homolog such as YbaK, ProX, or PrdX which supplies the function of INS in trans.	4.45476e-80
CP021963.1\|AWV27233.1\|2811005_2812259_+\|chitinase	gnl\|CDD\|119365	cd06548, GH18_chitinase, The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel.	1.16874e-96
CP021963.1\|AWV27235.1\|2813060_2813474_-\|peptide-methionine-(R)-S-oxide-reductase	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	1.07727e-93
CP021963.1\|AWV27232.1\|2809632_2810709_-\|alcohol-dehydrogenase	gnl\|CDD\|176219	cd08258, Zn_ADH4, Alcohol dehydrogenases of the MDR family. This group shares the zinc coordination sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of an beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	9.55347e-149
CP021963.1\|AWV27243.1\|2821693_2822977_+\|hypothetical-protein	gnl\|CDD\|377280	pfam04285, DUF444, Protein of unknown function (DUF444). Bacterial protein of unknown function. One family member is predicted to contain a von Willebrand factor (vWF) type A domain (Smart:VWA).	0
CP021963.1\|AWV27241.1\|2818457_2819204_-\|MipA/OmpV-family-protein	gnl\|CDD\|226236	COG3713, OmpV, Outer membrane protein V [Cell envelope biogenesis, outer membrane].	4.02433e-90
CP021963.1\|AWV27236.1\|2813815_2814811_+\|aldehyde-dehydrogenase	gnl\|CDD\|185323	PRK15425, gapA, glyceraldehyde-3-phosphate dehydrogenase.	0
CP021963.1\|AWV27238.1\|2816241_2817093_-\|hypothetical-protein	gnl\|CDD\|381364	cd19138, AKR_YeaE, Escherichia coli YeaE and similar proteins. Escherichia coli YeaE is the prototype of this family. It acts as an aldo-keto reductase (AKR) that catalyzes the reversible reduction of ketones to the respective alcohols using NAD(P)H as a hydride donor.	3.67549e-162
CP021963.1\|AWV27230.1\|2807165_2808209_-\|alcohol-dehydrogenase	gnl\|CDD\|176188	cd05285, sorbitol_DH, Sorbitol dehydrogenase. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit. Aldose reductase catalyzes the NADP(H)-dependent conversion of glucose to sorbital, and SDH uses NAD(H) in the conversion of sorbitol to fructose. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. The medium chain alcohol dehydrogenase family (MDR) have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit.	4.49491e-157

>CP021963.1|AWV27237.1|2814883_2815768_+|D-hexose-6-phosphate-mutarotase
MINKIFALPVIEQITPVLSRRQLDELEVLVVDHPQVKASFALQGAHLLSWKPNGEEEVLWLSNNTPFKTGVALRGGVPICWPWFGPAAKQGLPSHGFARNLPWTLKAHNEDDYGVVLTFELQSNAETRQLWPHEFCLLARFKVGATCEMELEAHGEFETTSALHTYFNVGDIAAVKVSGLGDRLIDKVNDAKEDVLADGIQTFPDRTDRVYLNPEACSVIHDDALNRNIDVVHHHHLNVVGWNPGPALSVSMGDMPDDGYKTFVCVETAYATAPQKTTEEKPSRLAQTIRVAKR
>CP021963.1|AWV27236.1|2813815_2814811_+|aldehyde-dehydrogenase
MTIKVGINGFGRIGRIVFRAAQERSDIEIVAINDLLDADYMAYMLKYDSTHGRFNGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVLTGPSKDNTPMFVKGANFDKYEGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAASYEEIKKAIKAASEGPMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK
>CP021963.1|AWV27235.1|2813060_2813474_-|peptide-methionine-(R)-S-oxide-reductase
MANQPSPEELKKNLTEMQFYVTQNHGTEPPFTGRLLHNKRDGIYHCLICDNPLFRSETKYDSGCGWPSFYEPVSDEAIRYIKDTSHGMQRIEIRCGNCDAHLGHVFPDGPKPTGERYCVNSASLNFTDGENGEQTKG
>CP021963.1|AWV27234.1|2812742_2813018_-|hypothetical-protein
MNLDEMINSMTPEVYQRLSTAVELGKWPDGVALTAEQKENSLQLVMLWQARNNIDAQHMTIDTNGEMVMKSKQQLKVEFGITPEPIATFKS
>CP021963.1|AWV29200.1|2812352_2812697_+|HNH-endonuclease
MAFIPKNYARLEVGYREKALKLFPWVCGRCSREFVYSNLRELTVHHIDHDHSNNPEDGSNWEMLCLYCHDHEHSKYTEADQYGSTVVAGEDAQKAVGEAKYNPFADLKAMMNKK
>CP021963.1|AWV27233.1|2811005_2812259_+|chitinase
MKLLPLLAALPLLCASVVSASSLMSVGYFNGGGDVTAGPGGDINKLDVRQITHLNYSFGLVYNNEKDETNDALKDASKLHQIWLSQKVQDDLLKIPQLRKQNPNLKVLLSVGGWGARGFSGAAATKETRAVFIQSAQEIIAKYGLDGIDLDWEYPVNGAWGLVESQPADRANFTALLTELRDALGHKKLLTIAVGANAESPKSWVDVKAIAPSLDYINLMTYDMAYGTQYFNSNLYDSTQWPTVAAADKYSADFVVNNYLAAGLKPSQMNLGIGFYGRVPKRAVEPGIDWSKPDAQKNPATQPYFESAQIELFKSLGVDLSKDTYVKYNDIVAKLINDPQKRFSQHWDDEAKVPWLSVQSADGKKLFALSYENPRSVAIKADYIKSKGLAGAMFWEYGADDNNQLAKQLADSLGIKH
>CP021963.1|AWV27232.1|2809632_2810709_-|alcohol-dehydrogenase
MKALARFGKAFGGYKMIDVPEPVCGPDDVVIEIKAAAICGADMKHYNVDSGSEQFNSIRGHEFAGQIVQVGDKVKDWKVGQRVVSDNSGHVCGVCPACEQGDFLCCTEKVNLGLDNNTWGGGFSKYCLVPGEILKIHRHALWEIPAGVDYEEAAVLDPICNAYKSIAQQSKFLPGQDVVVFGTGPLGLFSVQMARIMGAVNIVMVGLEEDVAVRFPIAKELGATAVVNGSTEDVVARCQEICGKDNLGLVIECSGANIALKQSIEMLRPNGEVVRVGMGFKPLDFSINDITAWNKSIIGHMAYDSTSWRNAIRLLASGAINVKPMITHRIGLSQWREGFDAMVDKTAIKVIMTYDFDE
>CP021963.1|AWV27231.1|2808226_2809606_-|MFS-transporter
MEQIAKPHCGARLDRLPDCRWHTSMFAMVAFGLLVCWSNAVGGLILAQLKELGWTDNSTTATFSAITTAGMFLGALGGGIIGDKTGRKNAFILYEAIHIISMIVGAFSPNMTFLIACRFVMGVGLGALLVTLFAGFTEYMPGRNRGTWSSRVSFIGNWSYPLCSLIAMGLTPLISAEWNWRVQLLIPAVLSLVATVIAWRSFPESPRWLESRGRYAEAEKVMRAIEEGVVQQTGKPLPPVVFEDDGKAPRTVPYSALLTGVLLKRVILGSFVLIAMNVVQYTLINWLPTIFMTQGINLKDSIVLNTMSMFGAPFGIFIAMLVMDKIPRKTTGVGLLVLIAVLGYIYSLQTSMLLITLIGFFLITFVYMYVCYASAVYVPEIWPTEAKLRGSGLANAVGRISGIAAPYAVAVLLNGYGVTGVFVLLGAVSIIVAVAIATIGIETKGVSVESLGIDAVTSK
>CP021963.1|AWV27230.1|2807165_2808209_-|alcohol-dehydrogenase
MKNSKAILKTPGTMKIIAADIPVPKEHEVLIKIEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGNRVSKFKPGDRVNIEPGVPCGHCRYCLEDKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHAAMLADVKPGKKIVILGAGCIGLMTLQACKCLGATDIAVVDVLEKRLAMAEQLGATTVINGAKEDTVARCQQFSGDMGADIVFETAGSAITVKQAPYLVMRGGKIMIVGTVPGDSAINFLKINREVSIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYEDVQRAFDESVNNKREIIKGVIKVNH
>CP021963.1|AWV27229.1|2806304_2807141_-|ketose-bisphosphate-aldolase
MLADIKYWENDAQNKHYAIAHFNVWNAEMLMGVMDAAEESKSPVIISFGTGFVGNTSFEDFSHMMVSMAKKASVPVITHWDHGRSMEIIHNAWTHGMNSLMRDASAFDFEENIRLTKEAVDFFHPLGIPVEAELGHVGNETVYEEALAGYHYTDPSQAAEFVERTGCDSLAVAIGNQHGVYTSEPKLNFDVVKRVREAVSVPLVLHGASGISDADIKKAISLGISKINIHTELCQAAMAAVQENQNQPFLHVEREVRNAVKERALEKIKLFGSDGKAE
>CP021963.1|AWV27238.1|2816241_2817093_-|hypothetical-protein
MTAKQVTFTNQVSLPAIGQGTWYMGEDPSRRRDEVSALQAGLDLGLRLIDTAEMYADGAAEEVVGEALTGRRDSAFLVSKVYPWNAGGQKAIAACEASLRRLKTDYLDLYLLHWMGDFSFAETIDAMETLIAQGKICRWGVSNLDYDDMQALWQVPGGRECATNQVLYHLASRGIEYDLLPWCQQQMPVMAYSPLAQAGRLRGDLLSNSVVNDIARAHNVSAAQILLAWVIRQSGVIAIPKAASVAHVEQNAAVLEITLSVDELKQLDKAYPAPKGKTALDMA
>CP021963.1|AWV27239.1|2817273_2817624_-|hypothetical-protein
MKKLIIIVALVASFAAPAYAISEAYRQQLQHEHKTMVSDTNAPVHASKIMPVHVNKLGVDFKRGADGIAYINGKPAANDENSAEAQSYSAGLTSVIVYKNGKINAMKEGKYLGRLK
>CP021963.1|AWV27240.1|2817634_2817877_-|hypothetical-protein
MKKLIMIAVMGGILAGCSTEASRMNACESKGVSRDACYVAEQNRQATINAAAEKQAMENAQNLYSTNDTNSSHHHKHDKY
>CP021963.1|AWV27241.1|2818457_2819204_-|MipA/OmpV-family-protein
MTKLKLLALGVLAATAVSTAQAESQWTVGAGVGVINSPYKQYDRDVYPVPVVTYEGDNVWFHGLGGGYYLWNDTADKLSIMAYYDPTHFKPGDSDSHALRQLDKRKSSLMAGLSYVHNTQYGFLRTALAGDTLDNSNGFIWDLAWLYRYTNGGLTLTPGIGVQYSSENYNDYYYGVSNHESRRSGLKSYNADDGWDPYLELTASYNFIGNWNVYGTGRYVRLSDEVKDSPMVDKSWSGIFSVGVTYKF
>CP021963.1|AWV27242.1|2819637_2821572_+|serine-protein-kinase-PrkA
MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLMAIGEPVMVDTAHEPRLSRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEKKQILYLLGPVGGGKSSLAERLKSLMQRVPIYVLSANGERSPVNDHPLCLFNPQEDAQILEKEYGIPRRYLGTIMSPWAAKRLHDFGGDITKFRVVKVWPSILEQIAIAKTEPGDENNQDISALVGKVDIRKLEHHAQNDPDAYGYSGALCRSNQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGTEGISALPFNGIILAHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLRISEEIKIYEKLLNHSELTHAPCAPGTLETLSRFTILSRLKEPENSSIYSKMRVYDGESLKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHAEVAANPVHLFYVLEQQIEREQFPQEQAERYLEFLKGYLIPKYAEFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPDTGQLFDRESLNSELEKIEKPAGISNPKDFRNEIVNFVLRARANNSGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNAKTSTDEQKKHDDFVDRMMEKGYTRKQVRLLCEWYLRVRKSS
>CP021963.1|AWV27243.1|2821693_2822977_+|hypothetical-protein
MTWFIDRRLNGKNKSTVNRQRFLRRYKSQIKQSISEAINKRSVTDVDSGESVSIPTDDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGFTSNGVPANISVVRSLQNSLARRTAMTAGKRRELHALEADLETIAKSEPAQLLEEERLRKEIAELRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNPAQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHLQSTFDNFAMQHIRDQDDIYPVFRELFHKQSTTSNS
>CP021963.1|AWV27244.1|2823071_2823842_-|SAM-dependent-methyltransferase
MSATEKAGHTFLASLGKTRLRPGGVEATEWLFSQSQLTPGSQVLEAACNMATTAIELVQRYGCTVYAIDMDKTALSNARNNVAANGLENHIHVMAANANTLPFADSSFDVVINEAMLTMYADKAKAKLIAEYYRVLKPGGRLLTHDIMFTAQKLGAGDQGQLVDVVKSNVSPMTRQGWRDLFLNCGFEQVLQQNGNMSLMSPRGLVRDEGLTGAVKIVFNGLRTSKNRRRFLKMFRFFRSQRHQLNYIACCSVKGK
>CP021963.1|AWV27245.1|2824006_2825497_+|diguanylate-cylase
MKLHHKALRIFISVSVIVLTSSFLVYELIASDKAMNAYMRYINEKADSSFLYDKYTNQSIAAHLMRTFSSPQGPASLEQQKVLCNAFDSVNGTHGLNLTKRNYLPLHGTLQTTSTKCSEQLDDIFLLPSFDRAVNVNRQQKDYGQGLGTLEYKFRYYVDLKNNYVYFYDVIDSRKFAIHNWSFLQKGTLGIDQNDIDGIFTGRTVISSIYEDNLTEKKVMSFLTPVYYANKLKGVVMVDINKENLQNIFYTSDRPLVWRYLNVMVSDTSSGKEILVHKSETDLFRYVHYEKDIPGGIRITLSLDVMYFIVSSWKIFAFYLLATILLLNMVRTHFRLYHNVTRENVSDAMTGLYNRKILTPALEQRLQQLVNTGTLVTFIAIDCDKLKVINDTLGHKEGDRIITILAKAIQTSIRKSDYAIRLGGDEFCIILIDHPSELTPRLLERIRYNLQIIAQDRSISFSVGIYNMQPNDTIDDAYKASDAQLYLNKQKKRTDA
>CP021963.1|AWV27246.1|2825541_2826045_+|YbaK/prolyl-tRNA-synthetase-associated-domain-containing-protein
MTEVNKGNATHQRLISLLSEHGATYRVVSHEAVGKCEAVSEIRGTALGQGAKALVCKVKGNGVNQHVLAILSADQQADLSLLASHIGGLRASLASPAEVDELTGCVFGAIPPFSFHPNLKLVADPLLFERFNEIAFNAGMLEKSVIMDTADYLRIAQPELIPFRREQ
>CP021963.1|AWV27247.1|2826182_2826629_+|DUF441-family-protein
MFDVTLLILLGLAALGFVSHNTTVAVSILVLIIVRVTPLNTFFPWIEKQGLTVGIIILTIGVMAPIASGTLPPSTLIHSFVNWKSLVAIAVGVFVSWLGGRGVTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ

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Crispr_ID: CP021963_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021963_3

4562263-4562411

Orphan

Consensus_repeat	Method
CTTGCGCCGCATCCGGCAACCGTTGTGCCTGATGGCGCTGCGCTTATCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP021963_3

>merge|CP021963|3|4562263-4562411|CRISPRCasFinder
CTTGCGCCGCATCCGGCAACCGTTGTGCCTGATGGCGCTGCGCTTATCAGGCCTACGAAACTACAGAATATGCATAAAGCCTGTAGGGCGGATAAGGCACTTGCGCCGCATCCGGCAACCGTTGTGCCTGATGGCGCTACGCTTATCAG

>CP021963|3|3|4562263-4562411|CRISPRCasFinder
CTTGCGCCGCATCCGGCAACCGTTGTGCCTGATGGCGCTGCGCTTATCAG	GCCTACGAAACTACAGAATATGCATAAAGCCTGTAGGGCGGATAAGGCA
CTTGCGCCGCATCCGGCAACCGTTGTGCCTGATGGCGCTACGCTTATCAG

Protein	Signature genes	Signature genes Name	Protein_function
CP021963.1\|AWV29270.1\|4567766_4568750_+\|quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|182701
CP021963.1\|AWV28760.1\|4549836_4550727_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176129
CP021963.1\|AWV28772.1\|4563868_4565062_-\|aromatic-amino-acid-aminotransferase	unknown	unknown	gnl\|CDD\|181731
CP021963.1\|AWV28764.1\|4555246_4555705_-\|redox-sensitive-transcriptional-activator-SoxR	unknown	unknown	gnl\|CDD\|184964
CP021963.1\|AWV28768.1\|4558604_4559129_-\|ssDNA-binding-protein	unknown	unknown	gnl\|CDD\|236362
CP021963.1\|AWV28763.1\|4553288_4554638_-\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
CP021963.1\|AWV28776.1\|4569305_4570304_-\|tRNA-dihydrouridine(20/20a)-synthase-DusA	unknown	unknown	gnl\|CDD\|236991
CP021963.1\|AWV28766.1\|4556117_4557704_-\|cyclic-diguanylate-phosphodiesterase	unknown	unknown	gnl\|CDD\|227279
CP021963.1\|AWV28762.1\|4551484_4553131_-\|Na+/H+-antiporter	unknown	unknown	gnl\|CDD\|129911
CP021963.1\|AWV28769.1\|4559380_4562203_+\|excinuclease-ABC-subunit-A	unknown	unknown	gnl\|CDD\|234734
CP021963.1\|AWV28773.1\|4565190_4566270_-\|alanine-racemase	unknown	unknown	gnl\|CDD\|143500
CP021963.1\|AWV28765.1\|4555791_4556115_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182314
CP021963.1\|AWV28778.1\|4571015_4571534_+\|transcriptional-regulator-Zur	unknown	unknown	gnl\|CDD\|183251
CP021963.1\|AWV28777.1\|4570411_4570900_-\|cupin	unknown	unknown	gnl\|CDD\|380353
CP021963.1\|AWV28771.1\|4562970_4563684_-\|acid-phosphatase/phosphotransferase	unknown	unknown	gnl\|CDD\|236818
CP021963.1\|AWV28774.1\|4566286_4567702_-\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|181193
CP021963.1\|AWV28770.1\|4562486_4562843_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225197
CP021963.1\|AWV28767.1\|4558256_4558538_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374240
CP021963.1\|AWV28761.1\|4550804_4551296_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224854
CP021963.1\|AWV28775.1\|4568929_4569172_-\|envelope-stress-response-protein-PspG	unknown	unknown	gnl\|CDD\|181875

Protein	Function_ID	Function_description	E-value
CP021963.1\|AWV29270.1\|4567766_4568750_+\|quinone-oxidoreductase	gnl\|CDD\|182701	PRK10754, PRK10754, NADPH:quinone reductase.	0
CP021963.1\|AWV28760.1\|4549836_4550727_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176129	cd08438, PBP2_CidR, The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold. This CD includes the substrate binding domain of CidR which positively up-regulates the expression of cidABC operon in the presence of acetic acid produced by the metabolism of excess glucose. The CidR affects the control of murein hydrolase activity by enhancing cidABC expression in the presence of acetic acid. Thus, up-regulation of cidABC expression results in increased murein hydrolase activity. This substrate binding domain has significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.04763e-89
CP021963.1\|AWV28772.1\|4563868_4565062_-\|aromatic-amino-acid-aminotransferase	gnl\|CDD\|181731	PRK09257, PRK09257, aromatic amino acid transaminase.	0
CP021963.1\|AWV28764.1\|4555246_4555705_-\|redox-sensitive-transcriptional-activator-SoxR	gnl\|CDD\|184964	PRK15002, PRK15002, redox-sensitive transcriptional activator SoxR.	2.81792e-107
CP021963.1\|AWV28768.1\|4558604_4559129_-\|ssDNA-binding-protein	gnl\|CDD\|236362	PRK09010, PRK09010, single-stranded DNA-binding protein; Provisional.	4.66491e-115
CP021963.1\|AWV28763.1\|4553288_4554638_-\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	2.76229e-144
CP021963.1\|AWV28776.1\|4569305_4570304_-\|tRNA-dihydrouridine(20/20a)-synthase-DusA	gnl\|CDD\|236991	PRK11815, PRK11815, tRNA dihydrouridine(20/20a) synthase DusA.	0
CP021963.1\|AWV28766.1\|4556117_4557704_-\|cyclic-diguanylate-phosphodiesterase	gnl\|CDD\|227279	COG4943, COG4943, Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms].	0
CP021963.1\|AWV28762.1\|4551484_4553131_-\|Na+/H+-antiporter	gnl\|CDD\|129911	TIGR00831, Putative_Na+/H+_exchanger_Rv2287/MT2345/Mb2309., Na+/H+ antiporter, bacterial form. The Monovalent Cation:Proton Antiporter-1 (CPA1) Family (TC 2.A.36) The CPA1 family is a large family of proteins derived from Gram-positive and Gram-negative bacteria, blue green bacteria, yeast, plants and animals. Transporters from eukaryotes have been functionally characterized, and all of these catalyze Na+:H+ exchange. Their primary physiological functions may be in (1) cytoplasmic pH regulation, extruding the H+ generated during metabolism, and (2) salt tolerance (in plants), due to Na+ uptake into vacuoles. This model is specific for the bacterial members of this family. [Transport and binding proteins, Cations and iron carrying compounds].	0
CP021963.1\|AWV28769.1\|4559380_4562203_+\|excinuclease-ABC-subunit-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP021963.1\|AWV28773.1\|4565190_4566270_-\|alanine-racemase	gnl\|CDD\|143500	cd06827, PLPDE_III_AR_proteobact, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases. This subfamily is composed mainly of proteobacterial alanine racemases (EC 5.1.1.1), fold type III PLP-dependent enzymes that catalyze the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. hese proteins are similar to other bacterial ARs and are fold type III PLP-dependent enzymes containing contains an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Homodimer formation and the presence of the PLP cofactor are required for catalytic activity.	0
CP021963.1\|AWV28765.1\|4555791_4556115_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|182314	PRK10219, PRK10219, superoxide response transcriptional regulator SoxS.	9.05826e-64
CP021963.1\|AWV28778.1\|4571015_4571534_+\|transcriptional-regulator-Zur	gnl\|CDD\|183251	PRK11639, PRK11639, zinc uptake transcriptional repressor Zur.	1.13317e-122
CP021963.1\|AWV28777.1\|4570411_4570900_-\|cupin	gnl\|CDD\|380353	cd02224, cupin_SPO2919-like, Silicibacter pomeroyi SPO2919 and related proteins, uncharacterized sugar phosphate isomerase with a cupin domain. This family includes proteins similar to sugar phosphate isomerase SPO2919 from Silicibacter pomeroyi and Afe_0303 from Acidithiobacillus ferrooxidans, but are as yet uncharacterized. Structures of these proteins show a cupin fold with a conserved "jelly roll-like" beta-barrel fold that form a homodimer.	1.51197e-42
CP021963.1\|AWV28771.1\|4562970_4563684_-\|acid-phosphatase/phosphotransferase	gnl\|CDD\|236818	PRK11009, aphA, class B acid phosphatase.	3.17046e-171
CP021963.1\|AWV28774.1\|4566286_4567702_-\|replicative-DNA-helicase	gnl\|CDD\|181193	PRK08006, PRK08006, replicative DNA helicase DnaB.	0
CP021963.1\|AWV28770.1\|4562486_4562843_-\|hypothetical-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	8.35622e-50
CP021963.1\|AWV28767.1\|4558256_4558538_+\|hypothetical-protein	gnl\|CDD\|374240	pfam15940, YjcB, Family of unknown function. This family of proteins is found in bacteria. Proteins in this family are approximately 90 amino acids in length.	9.24285e-41
CP021963.1\|AWV28761.1\|4550804_4551296_-\|hypothetical-protein	gnl\|CDD\|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.99238e-36
CP021963.1\|AWV28775.1\|4568929_4569172_-\|envelope-stress-response-protein-PspG	gnl\|CDD\|181875	PRK09459, pspG, envelope stress response protein PspG.	5.56761e-23

>CP021963.1|AWV28769.1|4559380_4562203_+|excinuclease-ABC-subunit-A
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPVIKERKGEHTKTLENLAGQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVIDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDPKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQMLKSLAEHYKFDVEAPWASLNPAVHKVVLYGSGKENIEFKYMNDRGDTSVRRHPFEGVLHNMERRYKETESSAVREELAKFISNRPCASCEGTRLRREARHVFVENTPLPAISDMSIGHAMDFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRNLGNTVIVVEHDEDAIRAADHVIDIGPGAGVHGGQVVAEGTLDDIMAVPESLTGQYMSGKRKIEVPKQRVAADPEKVLKLTGARGNNLKDVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQTALNGATLAEPAPYRDVQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHQLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPLL
>CP021963.1|AWV28768.1|4558604_4559129_-|ssDNA-binding-protein
MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKATGEMKEQTEWHRVVLFGKLAEVASEYLRKGSQVYIEGQLRTRKWTDQSGVEKYTTEVVVNVGGTMQMLGGRQGGGAPAGGGQQQGGWGQPQQPQGGNQFSGGAQSRPQQSAPAAPSNEPPMDFDDDIPF
>CP021963.1|AWV28767.1|4558256_4558538_+|hypothetical-protein
MATITTGVVLLRWQLLSAVLMFLASTLNIRFRKSDYIGLAVISSGLGLVFACWFATGLLGITLVDMSAIWKNIETVMVDVMSHTPPDWPMVLN
>CP021963.1|AWV28766.1|4556117_4557704_-|cyclic-diguanylate-phosphodiesterase
MNHSARRKMLKFLGTFMVVLFPVVLAIWFAHIRAMTETHSQLRSFAQLVLNKTELVILQADLARDMAQLYQGKMCTPAHQKSMLNIIRGRLYISELIYAQGDHFLCSTSMAPPVTYIMPTADYKRTPDIAIYYYRDTPFFAGYRMTYMQRGNYVAVINPLSYSEVMSDDPDLSWGVYDTVTDTFFSASEAANIAQFAPLIRGEASTFQQDDRFYTIVHSEKRPIAIIVSTSDNRVSQIFYHEAVLTIPFGIICSILILLMWWRTRQEYLSPRRLLKRAIKKRQLCLHYQPIIDIKNGQCVGAEALLRWPGCKGEVMSPTEFIPLAEKEGMIERITDYVVEEVFNDLGYFLSAHPQLSISINLSASDFHSSRLIALINDKNREYSVAAQQIKVEVTERGFIDVHKMTPVIQAFRKAGYEVAFDDFGTGYSNLHNLSALNVDILKIDKSFISTLSTNSTSHLIAEHIIEMAQSLHLKTIAEGVETKEQIEWLLERGVQYCQGWYFAKALPPQEFMHWIQRSPAILTQSGQ
>CP021963.1|AWV28765.1|4555791_4556115_+|AraC-family-transcriptional-regulator
MSHQQIIQTLIEWIDEHIDQPLNIEAVAKKSGYSKWYLQRMFRTVTRQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRREFDRTPSDYRHRL
>CP021963.1|AWV28764.1|4555246_4555705_-|redox-sensitive-transcriptional-activator-SoxR
MEKKLPRIKALLTPGEVAKRSGVAVSTLHFYESKGLISSMRNSGNQRRYKRDVLRYVAIIKIAQRIGIPLATIGDALGVLPEGHSLSAKEWKQLSSQWREELDRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDQLGEQGTGARLLEDD
>CP021963.1|AWV28763.1|4553288_4554638_-|NCS2-family-permease
MSTPSARTGGSLDAWFKISLRGSTVRQEVVAGLTTFLAMVYSVIVVPGMLGKAGFPPAAVFVATCLVAGVGSIVMGLWANLPLAIGCAISLTAFTAFSLVLGQHISVPVALGAVFLMGVLFTIISATGIRSWILRNLPQGVAHGTGIGIGLFLLLIAANGVGLVIKNPLDGLPVALGDFDTFPVIMSLIGLAVIIGLEKLKVPGGILLTIIGISVVGLIFDPAVHFSGIFAMPSLSDENGNSLIGSLDIMGALNPIVLPSVLALVMTAVFDATGTIRAVAGQANLLDKDGQIIDGGKALTTDSLSSVFSGLVGAAPAAVYIESAAGTAAGGKTGLTAITVGVLFLLILFLSPLSYLVPVYATAPALMYVGLLMLSNVAKIDFADFVDAMAGLVTAVFIVLTCNIVTGIMIGFATLVIGRIVSGEWRKLNIGTVVIAIALVAFYAGGWAI
>CP021963.1|AWV28762.1|4551484_4553131_-|Na+/H+-antiporter
MEIFFTILIMTLVVSLSGVFTRVLPFQLPLPLMQIAIGALLAWPTFGLHVEFDPELFLVLFIPPLLFADGWKTPTREFLEHGREIFGLALALVLVTVVGIGFMIYWLVPGIPLIPAFALAAVLSPTDAVALSGIVGEGRIPKKIMGILQGEALMNDASGLVSLKFAVAVAMGTMVFTVGGATLEFFKVAIGGILAGFVVSWLYGRSLRFLSRWGGDEPATQIVLLFLLPFASYLIAEHIGVSGILAAVAAGMTITRSGVMRRAPLAMRLRANSTWAMLEFVFNGMVFLLLGLQLPGILESSLAAAEADPNVEIWMLFTDVVLIYVALMLVRFGWLWTMKKFSLRFLKKKPMEFGSWTTREIMIASFAGVRGAITLAGVLSIPLLLPDGSGFPARYELIFLAAGVILFSLFVGVVMLPILLQHLEVADHSQQQKEERIARAATAEVAIVAIQKMEERLAADTEENIDNQLLTEVSSRVIGNLRRRADGRNDVESSMQEENLERRFRLAALRSERAELYHLRATREISNETLQKLLHDLDLLEALLIENQ
>CP021963.1|AWV28761.1|4550804_4551296_-|hypothetical-protein
MSNYRRNYINGGTWFFTVNLQDRRSHLLTDNIHALRCAIAAVKKVRPFRINAWVVLPEHMHCIWTLPGNDADYSSRWREIKKHFTHSLSSRHIWQSRFWEHTIRDEHDYRQHVDYIYINPVKHGWVKQVQDWPFSTFHRDVRHGLYPQDWAGEIMDFNAGERA
>CP021963.1|AWV28760.1|4549836_4550727_+|LysR-family-transcriptional-regulator
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCTLLIRDGRRLLLTDTGQVVFERGLAILAEFRQLEAELSDINHLNKGVLRLGIPPMVGMLMAGPIGLFRQRYPGVELKVSEFGGLTVQQAVMNGDLDVAMTALPVEEESGLATLPLFSHPLCVLVPRSGQWTTCESIPPEALAEHPLLIYNEDFALSRQLLELFSQHNVKPRIAVRSGQWDFLAAMVQAGVGIAILPEPICQRLDKQTLRWIPLESDLRWQLGMIWREGVYLSHSAQAWLKCCEGFWLPQAS
>CP021963.1|AWV28770.1|4562486_4562843_-|hypothetical-protein
MTNSELLQYCMAKTGAEQSVHSDWKATQIKVEDVLFAMVKEVEERPAVSLKTSPELAELLRQQHSDVRPSRHLNKAHWSTVYLDGSLPDSQIYYLVDASYQQAVNTLPEDKRRILTQP
>CP021963.1|AWV28771.1|4562970_4563684_-|acid-phosphatase/phosphotransferase
MRKFTLALSAVCLLFTLNQPAQALVSSPSQLNPGTNVAKLAEQAPIHWVSVAQIENSLTGRPPMAVGFDIDDTVLFSSPGFWRGKKTYSPDSEDYLKNPAFWEKMNNGWDEFSIPKEVARQLIDMHVRRGDSIFFVTGRSQTKTETVSKTLSDNFHIPAGNMNPVIFAGDKPGQNTKTQWLQDKNIRMFYGDSDNDITAARDVGIRGIRILRASNSTYKPLPQAGAFGEEVIVNSEY
>CP021963.1|AWV28772.1|4563868_4565062_-|aromatic-amino-acid-aminotransferase
MFQKVDAYAGDPILSLMERFKEDSRSDKVNLSIGLYYNEDGIIPQLKAVAEAEARFNAKPHGASLYLPMEGLNTYRHTIAPLLFGAEHPVLQQQRVATIQTLGGSGALKVGADFLKRYFPDSGVWVSDPTWENHIAIFEGAGFEVSTYPWYDDTTNGVRFNDLLATLNTLPARSIVLLHPCCHNPTGADLTPAQWDSVIEILKARDLIPFLDIAYQGFGGGMEDDAYAIRAIASAGLPALVSNSFSKIFSLYGERVGGLSVVCEDAETASRVLGQLKATVRRNYSSPPNFGAQVVAAVLGDDALKASWLAEVEEMRTRILAMRQELVNVLNTEIPGRNFDYLLQQRGMFSYTGLSAAQVDRLRDEFGVYLIASGRMCVAGLNHGNVQRVAKAFAAVM
>CP021963.1|AWV28773.1|4565190_4566270_-|alanine-racemase
MQAATVVINRRALRHNLQRLRELAPASKLVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAGGITQPILLLEGFFDASDLPTISAQRLHTAVHNQEQLEALEAAKLAEPVTVWMKLDTGMHRLGVRPEQAEAFYQRLTQCENVRQPVNIVSHFARADEPECGATEKQLDIFNSFCEGKPGQRSIAASGGILLWPQSHFDWARPGLILYGVSPLENHSIGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWQSERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPEAQDKAGDSVILWGEGLPVERIAEMTKVSAYELITRLTSRVAMKYID
>CP021963.1|AWV28774.1|4566286_4567702_-|replicative-DNA-helicase
MAGNKPFNKQQTDARERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVAEDFYTRPHRHIFTEMHRLQEMGKPIDLITLAESLEVQGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVRDMISVANEIAEAGFDPQGRSSEDLLDLAESRVFKIAESRANKDEGPKNITDVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQLMRVPSLSDNRTLEIAEISRSLKALAKELHVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQYDDE
>CP021963.1|AWV29270.1|4567766_4568750_+|quinone-oxidoreductase
MATRIEFHKHGGPDVLKAVEFTPVDPAENEIQVENKAIGINYIDTYIRSGLYPPPSLPSGLGTEAAGVVSKVGSKVTHIKAGDRVVYAQSALGAYSSVHNVPADKAAILPNAISFEQAAASFLKGLTVFYLLRKTYEIQPDEPFLFHAAAGGVGMIACQWAKALGAKLIGTVGSAQKAQIALQAGAWQVINYREESIVERVKEVTGGKKVRVVYDSVGKDTWEASLDCLQRRGLMVSFGNASGPVTGVNLGILNQKGSLYVTRPSLQGYITNHRELTEASNELFSLIASGVIKVDVAPGQTFALHDAQRAHEVLESRATQGSSLLIP
>CP021963.1|AWV28775.1|4568929_4569172_-|envelope-stress-response-protein-PspG
MLELLFVIGFFIMLMVTGVSLLGVLAALVVATAVMFLGGLFALMIKLLPWLLLAVAVVWVIKAIKAPKVPQYQRNNRRFY
>CP021963.1|AWV28776.1|4569305_4570304_-|tRNA-dihydrouridine(20/20a)-synthase-DusA
MLPESQSTAFPAHRFSIAPMLDWTDRHCRYFLRLLSSQTLLYTEMVTTGAIIHGKGDYLAYSEEEHPVALQLGGSDPAALAQCAKLAEQRGYDEINLNVGCPSDRVQNGMFGACLMGNAQLVADCIKAMRDVVSIPVTVKTRIGIDDQDSYEFLCDFINTVSGKGECEMFIIHARKAWLSGLSPKENREIPPLDYDRVYQLKRDFPHLTMSINGGIKSLEEAKIHLQHMDGVMVGREAYQNPGILASVDREIFAATTEDTDPVAVVRAMYPYIERELSKGTYLGHVTRHMLGLFQGIPGARQWRRYLSENAHKAGADINVLEHALKLVADKR
>CP021963.1|AWV28777.1|4570411_4570900_-|cupin
MKRPDCIRHWREVEGADDSTYPDSDELFAIGAPLARKLGLGRLGIHHERLPPGRRTSYPHAESDEEEFIYVLEGYPEAWINGYLWKLEPGDSVGFPAGTGVCHTFINNTSEEVRLLVVGEANKKYNRIYYPLNPVYAATREDRWVDHPPQFFGSHDGKPGRK
>CP021963.1|AWV28778.1|4571015_4571534_+|transcriptional-regulator-Zur
MDKTTTQELLAQAEKLCAQRNVRLTPQRLEVLRLMSLQEGAISAYDLLDLLRETEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHSSAMFICDRCGVVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCPACVEVESCRHPGECQHDHTIQVKKKVGR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP021963_1	1.3\|1010151\|33\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010151-1010183	33	JF974302	Vibrio phage VBpm10, * SEQUENCING IN PROGRESS *, 8 unordered pieces	8621-8653	5	0.848
CP021963_1	1.4\|1010213\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010213-1010244	32	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1247544-1247575	5	0.844
CP021963_1	1.4\|1010213\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010213-1010244	32	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	955747-955778	5	0.844
CP021963_1	1.4\|1010213\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010213-1010244	32	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1247688-1247719	5	0.844
CP021963_1	1.4\|1010213\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010213-1010244	32	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	995377-995408	5	0.844
CP021963_1	1.13\|1010762\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010762-1010793	32	MT843276	Serratia phage vB_SspS_OS31, complete genome	9950-9981	6	0.812
CP021963_1	1.15\|1010884\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010884-1010915	32	NZ_CP032350	Azospirillum brasilense strain MTCC4039 plasmid p5, complete sequence	73073-73104	6	0.812
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	789057-789088	7	0.781
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP027299	Streptomyces sp. SGAir0924 plasmid unnamed_5	53295-53326	8	0.75
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	185071-185102	8	0.75
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	MH113815	Pseudomonas phage Alpheus, complete genome	26169-26200	8	0.75
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	176490-176521	8	0.75
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP048638	Rhizobium oryzihabitans strain M15 plasmid p6, complete sequence	37823-37854	8	0.75
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP048639	Rhizobium oryzihabitans strain M15 plasmid p7, complete sequence	1809-1840	8	0.75
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP029836	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed6, complete sequence	47018-47049	8	0.75
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	176506-176537	8	0.75
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	176505-176536	8	0.75
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP042332	Bosea sp. F3-2 plasmid pB32-1, complete sequence	287296-287327	8	0.75
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	176503-176534	8	0.75
CP021963_1	1.6\|1010335\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010335-1010366	32	JQ809663	Stenotrophomonas phage Smp131, complete genome	707-738	8	0.75
CP021963_1	1.14\|1010823\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010823-1010854	32	CP000622	Burkholderia phage phiE255, complete genome	1655-1686	8	0.75
CP021963_1	1.14\|1010823\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010823-1010854	32	NC_009237	Burkholderia phage phiE255 chromosome, complete genome	1655-1686	8	0.75
CP021963_1	1.14\|1010823\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010823-1010854	32	NZ_CP026276	Klebsiella oxytoca strain KONIH5 plasmid pKOR-ab4d, complete sequence	161356-161387	8	0.75
CP021963_1	1.14\|1010823\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010823-1010854	32	NZ_CP022275	Citrobacter freundii strain 18-1 plasmid pBKPC18-1, complete sequence	29110-29141	8	0.75
CP021963_1	1.14\|1010823\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010823-1010854	32	LR134252	Klebsiella aerogenes strain NCTC9997 genome assembly, plasmid: 2	143875-143906	8	0.75
CP021963_1	1.14\|1010823\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010823-1010854	32	NZ_CP022349	Klebsiella michiganensis strain K516 plasmid pK516_KPC, complete sequence	73948-73979	8	0.75
CP021963_1	1.14\|1010823\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010823-1010854	32	NZ_CP036439	Klebsiella pneumoniae strain ABFQB plasmid unnamed1, complete sequence	79427-79458	8	0.75
CP021963_1	1.14\|1010823\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010823-1010854	32	NZ_CP023186	Klebsiella michiganensis strain K518 plasmid pK518_KPC, complete sequence	118457-118488	8	0.75
CP021963_1	1.14\|1010823\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010823-1010854	32	MN661402	Klebsiella quasipneumoniae strain KP18-31 plasmid pKP18-31-IMP,KPC, complete sequence	105621-105652	8	0.75
CP021963_1	1.16\|1010945\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010945-1010976	32	NC_022437	Pseudomonas fluorescens R124 plasmid pMP-R124, complete sequence	13265-13296	8	0.75
CP021963_1	1.2\|1010090\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010090-1010121	32	NZ_CP049040	Pseudohalocynthiibacter aestuariivivens strain RR4-35 plasmid pRR4-35_3, complete sequence	87512-87543	9	0.719
CP021963_1	1.4\|1010213\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010213-1010244	32	NC_007766	Rhizobium etli CFN 42 plasmid p42f, complete sequence	454649-454680	9	0.719
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP041514	Klebsiella michiganensis strain KNU07 plasmid unnamed, complete sequence	102721-102752	9	0.719
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP033823	Klebsiella sp. FDAARGOS_511 plasmid unnamed1, complete sequence	70339-70370	9	0.719
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	436368-436399	9	0.719
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP008843	Klebsiella michiganensis strain M1 plasmid pKOXM1B, complete sequence	79439-79470	9	0.719
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP024642	Klebsiella michiganensis strain F107 plasmid unnamed2, complete sequence	91679-91710	9	0.719
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP042547	Klebsiella michiganensis strain C52 plasmid pC52_002, complete sequence	18325-18356	9	0.719
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP026198	Enterobacteriaceae bacterium ENNIH3 plasmid pKPC-c606, complete sequence	144387-144418	9	0.719
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP025983	Enterobacteriaceae bacterium A-F18 plasmid pAF18_1, complete sequence	113932-113963	9	0.719
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP018361	Klebsiella oxytoca strain CAV1752 plasmid pCAV1752-278, complete sequence	53065-53096	9	0.719
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP026189	Enterobacteriaceae bacterium ENNIH2 plasmid pENT-812c, complete sequence	143437-143468	9	0.719
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP026718	Klebsiella oxytoca strain AR_0028 plasmid unitig_3_pilon, complete sequence	40544-40575	9	0.719
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	NZ_CP044111	Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2	182871-182902	9	0.719
CP021963_1	1.8\|1010457\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010457-1010488	32	NZ_CP015737	Shinella sp. HZN7 plasmid pShin-01, complete sequence	447466-447497	9	0.719
CP021963_1	1.8\|1010457\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010457-1010488	32	NZ_CP018229	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence	520053-520084	9	0.719
CP021963_1	1.15\|1010884\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010884-1010915	32	NZ_HG938356	Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence	750025-750056	9	0.719
CP021963_1	1.5\|1010274\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010274-1010305	32	MN820898	Sphingomonas phage vB_StuS_MMDA13, complete genome	43997-44028	10	0.688
CP021963_1	1.7\|1010396\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010396-1010427	32	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	302139-302170	10	0.688
CP021963_1	1.7\|1010396\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010396-1010427	32	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	1339686-1339717	10	0.688
CP021963_1	1.14\|1010823\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010823-1010854	32	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	138613-138644	10	0.688
CP021963_1	1.14\|1010823\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010823-1010854	32	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1674504-1674535	10	0.688
CP021963_1	1.14\|1010823\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010823-1010854	32	NZ_CP018080	Sulfitobacter sp. AM1-D1 plasmid unnamed4, complete sequence	160391-160422	10	0.688
CP021963_1	1.15\|1010884\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010884-1010915	32	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1795812-1795843	10	0.688
CP021963_1	1.20\|1011189\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1011189-1011220	32	NZ_KY416992	Escherichia coli strain FAM21805 plasmid unnamed, complete sequence	41104-41135	10	0.688
CP021963_1	1.20\|1011189\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1011189-1011220	32	NZ_KY416992	Escherichia coli strain FAM21805 plasmid unnamed, complete sequence	50792-50823	10	0.688
CP021963_1	1.20\|1011189\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1011189-1011220	32	NZ_KY416992	Escherichia coli strain FAM21805 plasmid unnamed, complete sequence	64086-64117	10	0.688
CP021963_1	1.20\|1011189\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1011189-1011220	32	NC_019013	Escherichia coli strain G3/10 plasmid pSYM1, complete sequence	14571-14602	10	0.688
CP021963_1	1.20\|1011189\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1011189-1011220	32	NZ_LT883139	Escherichia coli isolate 6666666.257727.embl plasmid I	1841-1872	10	0.688
CP021963_1	1.20\|1011189\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1011189-1011220	32	NZ_LT883139	Escherichia coli isolate 6666666.257727.embl plasmid I	106567-106598	10	0.688
CP021963_1	1.21\|1011250\|32\|CP021963\|CRISPRCasFinder,CRT	1011250-1011281	32	NC_014838	Pantoea sp. At-9b plasmid pPAT9B01, complete sequence	480130-480161	10	0.688
CP021963_1	1.14\|1010823\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010823-1010854	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3924534-3924565	11	0.656
CP021963_1	1.14\|1010823\|32\|CP021963\|PILER-CR,CRISPRCasFinder,CRT	1010823-1010854	32	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	608774-608805	11	0.656

1. spacer 1.3|1010151|33|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to JF974302 (Vibrio phage VBpm10, *** SEQUENCING IN PROGRESS ***, 8 unordered pieces) position: , mismatch: 5, identity: 0.848

-cgccgcagatccctgagctgctgtttgacctgc	CRISPR spacer
atgac-caaatccctgagctgctgtttgacttgc	Protospacer
 .* * **.*********************.***

2. spacer 1.4|1010213|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.844

aatgcaacgccctgagcgccgacgtaagccgc--	CRISPR spacer
gatgcaacgccctgaccgctgacg--agccgccc	Protospacer
.************** ***.****  ******

3. spacer 1.4|1010213|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 5, identity: 0.844

aatgcaacgccctgagcgccgacgtaagccgc--	CRISPR spacer
gatgcaacgccctgaccgctgacg--agccgccc	Protospacer
.************** ***.****  ******

4. spacer 1.4|1010213|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.844

aatgcaacgccctgagcgccgacgtaagccgc--	CRISPR spacer
gatgcaacgccctgaccgctgacg--agccgccc	Protospacer
.************** ***.****  ******

5. spacer 1.4|1010213|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.844

aatgcaacgccctgagcgccgacgtaagccgc--	CRISPR spacer
gatgcaacgccctgaccgctgacg--agccgccc	Protospacer
.************** ***.****  ******

6. spacer 1.13|1010762|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to MT843276 (Serratia phage vB_SspS_OS31, complete genome) position: , mismatch: 6, identity: 0.812

gtgatcggcctgtccggtacaccattcactaa	CRISPR spacer
gttatcggcctgtccggtacaccgttctccgc	Protospacer
** ********************.*** *..

7. spacer 1.15|1010884|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032350 (Azospirillum brasilense strain MTCC4039 plasmid p5, complete sequence) position: , mismatch: 6, identity: 0.812

cgctggagcaggacgcagcggacggc-acattt	CRISPR spacer
tgctgcagcaggacgcggcggacgactacatc-	Protospacer
.**** **********.*******.* ****.

8. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 7, identity: 0.781

acgacgacccggcgcagaccgccat-cgaccgg	CRISPR spacer
gggacgatccggcgcaggccgccatacgatcc-	Protospacer
. *****.*********.******* ***.*

9. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027299 (Streptomyces sp. SGAir0924 plasmid unnamed_5) position: , mismatch: 8, identity: 0.75

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
cgcacgacccggcgcagaccgtcgtcgacgct	Protospacer
   ******************.*.*****

10. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 8, identity: 0.75

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
ggatcgaccaggcccagaccgccatcgaccac	Protospacer
. . ***** *** ****************.

11. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to MH113815 (Pseudomonas phage Alpheus, complete genome) position: , mismatch: 8, identity: 0.75

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
acgacgacctgccgcagaccgccaaggatgcc	Protospacer
*********.* ************  **.

12. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tcgccccaccggcgcaggccgacatcgaccga	Protospacer
 ** *   *********.*** *********.

13. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP048638 (Rhizobium oryzihabitans strain M15 plasmid p6, complete sequence) position: , mismatch: 8, identity: 0.75

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
ctggcgtttcggcgcagatcgtcatcgaccgg	Protospacer
 .*.** ..*********.**.**********

14. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP048639 (Rhizobium oryzihabitans strain M15 plasmid p7, complete sequence) position: , mismatch: 8, identity: 0.75

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
ctggcgtttcggcgcagatcgtcatcgaccgg	Protospacer
 .*.** ..*********.**.**********

15. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029836 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed6, complete sequence) position: , mismatch: 8, identity: 0.75

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
ccgccgacccggcgctgaccgccaagcagcgc	Protospacer
 ** *********** ********   * **

16. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tcgccccaccggcgcaggccgacatcgaccga	Protospacer
 ** *   *********.*** *********.

17. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tcgccccaccggcgcaggccgacatcgaccga	Protospacer
 ** *   *********.*** *********.

18. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042332 (Bosea sp. F3-2 plasmid pB32-1, complete sequence) position: , mismatch: 8, identity: 0.75

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
gcatcgacccggcgcggatcgccatcgtcacg	Protospacer
.*. ***********.**.******** *  *

19. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tcgccccaccggcgcaggccgacatcgaccga	Protospacer
 ** *   *********.*** *********.

20. spacer 1.6|1010335|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to JQ809663 (Stenotrophomonas phage Smp131, complete genome) position: , mismatch: 8, identity: 0.75

cacatagttaaccgtgtcccagtcggacaagt-	CRISPR spacer
gtcatagttaaccgggtcgcagtc-gtcgcgtg	Protospacer
  ************ *** ***** * *. **

21. spacer 1.14|1010823|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to CP000622 (Burkholderia phage phiE255, complete genome) position: , mismatch: 8, identity: 0.75

atactggccgttgccccgggcatcgagcttaa	CRISPR spacer
gtactggccgttgccgcgcgcatcgaaggcac	Protospacer
.************** ** *******.  .*

22. spacer 1.14|1010823|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NC_009237 (Burkholderia phage phiE255 chromosome, complete genome) position: , mismatch: 8, identity: 0.75

atactggccgttgccccgggcatcgagcttaa	CRISPR spacer
gtactggccgttgccgcgcgcatcgaaggcac	Protospacer
.************** ** *******.  .*

23. spacer 1.14|1010823|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026276 (Klebsiella oxytoca strain KONIH5 plasmid pKOR-ab4d, complete sequence) position: , mismatch: 8, identity: 0.75

atactggccgttgccccgggcatcgagcttaa	CRISPR spacer
acagtggccaatgccccgggcatcgaggaaac	Protospacer
*.* *****. ****************   *

24. spacer 1.14|1010823|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022275 (Citrobacter freundii strain 18-1 plasmid pBKPC18-1, complete sequence) position: , mismatch: 8, identity: 0.75

atactggccgttgccccgggcatcgagcttaa	CRISPR spacer
acagtggccaatgccccgggcatcgaggaaac	Protospacer
*.* *****. ****************   *

25. spacer 1.14|1010823|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to LR134252 (Klebsiella aerogenes strain NCTC9997 genome assembly, plasmid: 2) position: , mismatch: 8, identity: 0.75

atactggccgttgccccgggcatcgagcttaa	CRISPR spacer
acagtggccaatgccccgggcatcgaggaaac	Protospacer
*.* *****. ****************   *

26. spacer 1.14|1010823|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022349 (Klebsiella michiganensis strain K516 plasmid pK516_KPC, complete sequence) position: , mismatch: 8, identity: 0.75

atactggccgttgccccgggcatcgagcttaa	CRISPR spacer
acagtggccaatgccccgggcatcgaggaaac	Protospacer
*.* *****. ****************   *

27. spacer 1.14|1010823|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP036439 (Klebsiella pneumoniae strain ABFQB plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

atactggccgttgccccgggcatcgagcttaa	CRISPR spacer
acagtggccaatgccccgggcatcgaggaaac	Protospacer
*.* *****. ****************   *

28. spacer 1.14|1010823|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023186 (Klebsiella michiganensis strain K518 plasmid pK518_KPC, complete sequence) position: , mismatch: 8, identity: 0.75

atactggccgttgccccgggcatcgagcttaa	CRISPR spacer
acagtggccaatgccccgggcatcgaggaaac	Protospacer
*.* *****. ****************   *

29. spacer 1.14|1010823|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to MN661402 (Klebsiella quasipneumoniae strain KP18-31 plasmid pKP18-31-IMP,KPC, complete sequence) position: , mismatch: 8, identity: 0.75

atactggccgttgccccgggcatcgagcttaa	CRISPR spacer
acagtggccaatgccccgggcatcgaggaaac	Protospacer
*.* *****. ****************   *

30. spacer 1.16|1010945|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NC_022437 (Pseudomonas fluorescens R124 plasmid pMP-R124, complete sequence) position: , mismatch: 8, identity: 0.75

acggcatgaaaatgctgatgggccaaatggcg	CRISPR spacer
aaaacatgaaaatgctgatggaacaaaaagag	Protospacer
* ..*****************. **** .* *

31. spacer 1.2|1010090|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049040 (Pseudohalocynthiibacter aestuariivivens strain RR4-35 plasmid pRR4-35_3, complete sequence) position: , mismatch: 9, identity: 0.719

agaggaagaatgaaaaaggtgatcaccccgcg	CRISPR spacer
ggaggaagaatgaagaagttgatcgtcgggat	Protospacer
.*************.*** *****..*  *

32. spacer 1.4|1010213|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NC_007766 (Rhizobium etli CFN 42 plasmid p42f, complete sequence) position: , mismatch: 9, identity: 0.719

aatgcaacgccctgagcgccgacgtaagccgc	CRISPR spacer
acataaacgccctgagtgccgccgtaagactt	Protospacer
*    ***********.**** ****** * .

33. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041514 (Klebsiella michiganensis strain KNU07 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tccgataccggacgcagaccgccatcgaccat	Protospacer
 * .  *** *.******************.

34. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033823 (Klebsiella sp. FDAARGOS_511 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tccgataccggacgcagaccgccatcgaccat	Protospacer
 * .  *** *.******************.

35. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
agatcgacccggcgcacaccgccgtcgccttc	Protospacer
* . ************ ******.*** *.

36. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP008843 (Klebsiella michiganensis strain M1 plasmid pKOXM1B, complete sequence) position: , mismatch: 9, identity: 0.719

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tccgataccggacgcagaccgccatcgaccat	Protospacer
 * .  *** *.******************.

37. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024642 (Klebsiella michiganensis strain F107 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tccgataccggacgcagaccgccatcgaccat	Protospacer
 * .  *** *.******************.

38. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042547 (Klebsiella michiganensis strain C52 plasmid pC52_002, complete sequence) position: , mismatch: 9, identity: 0.719

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tccgataccggacgcagaccgccatcgaccat	Protospacer
 * .  *** *.******************.

39. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026198 (Enterobacteriaceae bacterium ENNIH3 plasmid pKPC-c606, complete sequence) position: , mismatch: 9, identity: 0.719

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tccgataccggacgcagaccgccatcgaccat	Protospacer
 * .  *** *.******************.

40. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025983 (Enterobacteriaceae bacterium A-F18 plasmid pAF18_1, complete sequence) position: , mismatch: 9, identity: 0.719

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tccgataccggacgcagaccgccatcgaccat	Protospacer
 * .  *** *.******************.

41. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018361 (Klebsiella oxytoca strain CAV1752 plasmid pCAV1752-278, complete sequence) position: , mismatch: 9, identity: 0.719

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tccgataccggacgcagaccgccatcgaccat	Protospacer
 * .  *** *.******************.

42. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026189 (Enterobacteriaceae bacterium ENNIH2 plasmid pENT-812c, complete sequence) position: , mismatch: 9, identity: 0.719

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tccgataccggacgcagaccgccatcgaccat	Protospacer
 * .  *** *.******************.

43. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026718 (Klebsiella oxytoca strain AR_0028 plasmid unitig_3_pilon, complete sequence) position: , mismatch: 9, identity: 0.719

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tccgataccggacgcagaccgccatcgaccat	Protospacer
 * .  *** *.******************.

44. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044111 (Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2) position: , mismatch: 9, identity: 0.719

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
tccgataccggacgcagaccgccatcgaccat	Protospacer
 * .  *** *.******************.

45. spacer 1.8|1010457|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015737 (Shinella sp. HZN7 plasmid pShin-01, complete sequence) position: , mismatch: 9, identity: 0.719

aggtccaggagagcgccatgcgtatcacgaca	CRISPR spacer
gcgcccaggagagcgccatgcggaccagttcc	Protospacer
. *.****************** *.**   *

46. spacer 1.8|1010457|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018229 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

aggtccaggagagcgccatgcgtatcacgaca	CRISPR spacer
gcgcccaggagagcgccatgcgcaccaggttt	Protospacer
. *.******************.*.** * .

47. spacer 1.15|1010884|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_HG938356 (Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence) position: , mismatch: 9, identity: 0.719

cgctggagcaggacgcagcggacggcacattt	CRISPR spacer
gggtggagcaggaggccgcggacggcttcatc	Protospacer
 * ********** ** ********* .  *.

48. spacer 1.5|1010274|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to MN820898 (Sphingomonas phage vB_StuS_MMDA13, complete genome) position: , mismatch: 10, identity: 0.688

acgacgacccggcgcagaccgccatcgaccgg	CRISPR spacer
ttctgttcccgccgcagaccggcatcgaccgc	Protospacer
 .     **** ********* *********

49. spacer 1.7|1010396|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

gtggaatggcgagaaggcgcaggcctttatgc	CRISPR spacer
gccaggcagcgagaaggcgcaggccgttgtgg	Protospacer
*. .....***************** **.**

50. spacer 1.7|1010396|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 10, identity: 0.688

gtggaatggcgagaaggcgcaggcctttatgc	CRISPR spacer
cctcagccccgagcaggcgcaggcctttacgc	Protospacer
 .  *..  **** ***************.**

51. spacer 1.14|1010823|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 10, identity: 0.688

atactggccgttgccccgggcatcgagcttaa	CRISPR spacer
gcggcggccgtggccctgggcatcgagcccac	Protospacer
... .****** ****.***********..*

52. spacer 1.14|1010823|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 10, identity: 0.688

atactggccgttgccccgggcatcgagcttaa	CRISPR spacer
gcggcggccgtggccctgggcatcgagcccac	Protospacer
... .****** ****.***********..*

53. spacer 1.14|1010823|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018080 (Sulfitobacter sp. AM1-D1 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.688

atactggccgttgccccgggcatcgagcttaa	CRISPR spacer
gatccggccgttgccccgggcctccagcgcgt	Protospacer
.  *.**************** ** *** ..

54. spacer 1.15|1010884|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 10, identity: 0.688

cgctggagcaggacgcagcggacggcacattt	CRISPR spacer
ccctggagcaggtcgcagccgacggagaccag	Protospacer
* ********** ****** ***** .  .

55. spacer 1.20|1011189|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY416992 (Escherichia coli strain FAM21805 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

gatacgcctgaattcgacgttatctcgccaac	CRISPR spacer
ttgatatctgaattcggcgttatctccccaca	Protospacer
   *...*********.********* ***

56. spacer 1.20|1011189|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY416992 (Escherichia coli strain FAM21805 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

gatacgcctgaattcgacgttatctcgccaac	CRISPR spacer
ttgatatctgaattcggcgttatctccccaca	Protospacer
   *...*********.********* ***

57. spacer 1.20|1011189|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY416992 (Escherichia coli strain FAM21805 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

gatacgcctgaattcgacgttatctcgccaac	CRISPR spacer
ttgatatctgaattcggcgttatctccccaca	Protospacer
   *...*********.********* ***

58. spacer 1.20|1011189|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NC_019013 (Escherichia coli strain G3/10 plasmid pSYM1, complete sequence) position: , mismatch: 10, identity: 0.688

gatacgcctgaattcgacgttatctcgccaac	CRISPR spacer
ttgatatctgaattcggcgttatctccccaca	Protospacer
   *...*********.********* ***

59. spacer 1.20|1011189|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT883139 (Escherichia coli isolate 6666666.257727.embl plasmid I) position: , mismatch: 10, identity: 0.688

gatacgcctgaattcgacgttatctcgccaac	CRISPR spacer
ttgatatctgaattcggcgttatctccccaca	Protospacer
   *...*********.********* ***

60. spacer 1.20|1011189|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT883139 (Escherichia coli isolate 6666666.257727.embl plasmid I) position: , mismatch: 10, identity: 0.688

gatacgcctgaattcgacgttatctcgccaac	CRISPR spacer
ttgatatctgaattcggcgttatctccccaca	Protospacer
   *...*********.********* ***

61. spacer 1.21|1011250|32|CP021963|CRISPRCasFinder,CRT matches to NC_014838 (Pantoea sp. At-9b plasmid pPAT9B01, complete sequence) position: , mismatch: 10, identity: 0.688

aatttatccgggactacaacatatctctttat	CRISPR spacer
tgtttatcccggactacaacatttcggtggcc	Protospacer
 .******* ************ **  *   .

62. spacer 1.14|1010823|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 11, identity: 0.656

atactggccgttgccccgggcatcgagcttaa	CRISPR spacer
tcggcggccgtcgccccgggcatcgggcacgg	Protospacer
 .. .******.*************.** ...

63. spacer 1.14|1010823|32|CP021963|PILER-CR,CRISPRCasFinder,CRT matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 11, identity: 0.656

atactggccgttgccccgggcatcgagcttaa	CRISPR spacer
gccgtggccgttgccccgaccatcgaggcgct	Protospacer
..  **************. ******* .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1749278 : 1757845

Enterobacteria_phage(66.67%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV26259.1\|1749278_1750226_+	ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	1.7e-07	25.3
AWV26260.1\|1750209_1750941_+	osmoprotectant uptake system permease	NA	NA	NA	NA
AWV26261.1\|1750921_1751029_-	hypothetical protein	NA	NA	NA	NA
AWV26262.1\|1751228_1751960_-	transcriptional regulator	Q9EYF2	Enterobacteria_phage	1.5e-104	93.0
AWV26263.1\|1752185_1753871_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	2.1e-279	91.1
AWV26264.1\|1753867_1754587_+	DNA-binding response regulator	NA	NA	NA	NA
AWV29161.1\|1754633_1755104_+	hypothetical protein	Q9EYF4	Enterobacteria_phage	1.8e-63	77.4
AWV26265.1\|1755147_1755606_-	hypothetical protein	Q9EYF5	Enterobacteria_phage	3.2e-52	69.9
AWV26266.1\|1755811_1757845_-\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	2.0e-53	27.6

DBSCAN-SWA_2

1798862 : 1808440

Bacillus_phage(28.57%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV26305.1\|1798862_1800809_+	macrolide ABC transporter permease/ATP-binding protein MacB	G9BWD6	Planktothrix_phage	3.7e-41	42.2
AWV26306.1\|1800883_1801108_-	cold shock domain protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	3.6e-17	62.7
AWV26307.1\|1801431_1801752_+\|protease	ATP-dependent Clp protease adaptor ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	3.5e-13	45.7
AWV26308.1\|1801782_1804059_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.4e-164	42.1
AWV26309.1\|1804328_1805690_-	U32 family peptidase	Q6DW11	Phage_TP	5.3e-204	92.9
AWV26310.1\|1805849_1806182_-	hypothetical protein	NA	NA	NA	NA
AWV26311.1\|1806317_1807040_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	9.2e-30	32.7
AWV26312.1\|1807036_1808440_-	two-component system sensor histidine kinase BaeA	W8CYF6	Bacillus_phage	2.3e-32	29.2

DBSCAN-SWA_3

1851832 : 1860830

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV26343.1\|1851832_1852828_+	UDP-N-acetylglucosamine 4-epimerase	A0A0K1L6Z1	Scale_drop_disease_virus	6.6e-10	28.5
AWV26344.1\|1853065_1853959_+	GalU regulator GalF	A0A127AW70	Bacillus_phage	4.8e-44	40.9
AWV26345.1\|1854379_1855408_+	glycosyl transferase	NA	NA	NA	NA
AWV26346.1\|1855418_1856537_+	GDP-mannose 4,6-dehydratase	M1HVG7	Acanthocystis_turfacea_Chlorella_virus	3.1e-133	64.7
AWV26347.1\|1856540_1857506_+	GDP-fucose synthetase	D1LW79	Prochlorococcus_phage	1.2e-85	50.5
AWV26348.1\|1857508_1858009_+	GDP-mannose mannosyl hydrolase	NA	NA	NA	NA
AWV26349.1\|1858001_1859450_+	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	1.0e-56	32.4
AWV26350.1\|1859453_1860830_+	phosphomannomutase	A0A127AWJ1	Bacillus_phage	1.2e-30	26.4

DBSCAN-SWA_4

2743958 : 2753966

Brazilian_cedratvirus(28.57%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV27166.1\|2743958_2744738_+	heme ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.3e-10	26.9
AWV27167.1\|2744734_2746177_-	hypothetical protein	A0A075BSJ0	Microcystis_phage	2.2e-51	35.3
AWV27168.1\|2746238_2746952_-	EAL domain-containing protein	NA	NA	NA	NA
AWV27169.1\|2747270_2747735_-	endopeptidase	A0A1V0DZX6	Clostridioides_phage	3.5e-14	38.2
AWV27170.1\|2747812_2748562_-	vitamin B12 ABC transporter ATP-binding protein BtuD	A0A2R8FG22	Brazilian_cedratvirus	9.3e-09	30.3
AWV27171.1\|2748561_2749113_-	glutathione peroxidase	NA	NA	NA	NA
AWV27172.1\|2749173_2750154_-	vitamin B12 ABC transporter permease BtuC	A0A2H4IY97	uncultured_Caudovirales_phage	6.7e-15	24.8
AWV27173.1\|2750275_2750575_-	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	7.2e-13	40.0
AWV27174.1\|2750579_2752967_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
AWV27175.1\|2752982_2753966_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	1.4e-33	38.5

DBSCAN-SWA_5

3115749 : 3207170

Salmonella_phage(66.67%)

head,capsid,portal,tRNA,tail,plate,integrase,transposase

attL 3145136:3145160|attR 3180343:3180367

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV27507.1\|3115749_3117042_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	4.3e-94	48.0
AWV27508.1\|3117134_3118478_-	recombination factor protein RarA	G3MBE0	Bacillus_virus	1.9e-81	41.0
AWV27509.1\|3118488_3119100_-	outer membrane lipoprotein carrier protein LolA	NA	NA	NA	NA
AWV27510.1\|3119211_3123276_-	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	2.9e-88	49.2
AWV27511.1\|3123410_3123905_-	leucine-responsive regulatory protein	NA	NA	NA	NA
AWV27512.1\|3124452_3125421_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	1.9e-62	44.3
AWV27513.1\|3125535_3127302_+	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	W8CYL7	Bacillus_phage	2.7e-22	23.3
AWV27514.1\|3127302_3129024_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	W8CYL7	Bacillus_phage	2.4e-15	23.6
AWV27515.1\|3129068_3129773_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
AWV27516.1\|3130058_3130277_+	translation initiation factor IF-1	NA	NA	NA	NA
AWV27517.1\|3130356_3131268_-	LysR family transcriptional regulator	NA	NA	NA	NA
AWV27518.1\|3131376_3132237_+	quercetin 2,3-dioxygenase	NA	NA	NA	NA
AWV27519.1\|3132253_3132931_+	amidohydrolase	NA	NA	NA	NA
AWV27520.1\|3133318_3134446_-	23S rRNA (uracil(747)-C(5))-methyltransferase	A0A1X9I6F4	Streptococcus_phage	5.5e-29	27.7
AWV27521.1\|3134487_3134976_-	hypothetical protein	NA	NA	NA	NA
AWV27522.1\|3135035_3135881_-	putrescine ABC transporter permease PotI	NA	NA	NA	NA
AWV27523.1\|3135877_3136831_-	putrescine ABC transporter permease	NA	NA	NA	NA
AWV27524.1\|3136840_3137974_-	polyamine ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-29	34.9
AWV27525.1\|3138112_3139225_-	spermidine/putrescine ABC transporter substrate-binding protein PotF	NA	NA	NA	NA
AWV27526.1\|3139658_3140135_-	YbjN domain-containing protein	NA	NA	NA	NA
AWV27527.1\|3140225_3141128_-	30S ribosomal protein S6--L-glutamate ligase	I3ULC9	Synechococcus_phage	4.4e-37	33.6
AWV27528.1\|3141187_3141910_-	NADPH-dependent oxidoreductase	NA	NA	NA	NA
AWV27529.1\|3141893_3142184_-	hypothetical protein	NA	NA	NA	NA
AWV27530.1\|3142356_3142620_+	glutaredoxin, GrxA family	A0A2I7SAE2	Vibrio_phage	1.5e-25	66.7
AWV27531.1\|3142654_3143035_-	hypothetical protein	NA	NA	NA	NA
AWV27532.1\|3143304_3144990_+	transporter	NA	NA	NA	NA
3145136:3145160	attL	NA	NA	NA	NA
AWV27533.1\|3145279_3145495_-	late control protein B	Q53ZE7	Salmonella_virus	7.9e-22	69.4
AWV27534.1\|3145562_3146663_-	late control protein D	E5G6Q3	Salmonella_phage	1.1e-188	94.3
AWV27535.1\|3146659_3147145_-\|tail	phage tail protein	E5G6Q2	Salmonella_phage	2.5e-63	95.4
AWV27536.1\|3147141_3150207_-\|tail	phage tail tape measure protein	A0A1S6L010	Salmonella_phage	0.0e+00	78.6
AWV27537.1\|3150199_3150319_-\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	6.7e-15	97.4
AWV27538.1\|3150333_3150636_-\|tail	phage tail assembly protein	A0A1S6KZZ9	Salmonella_phage	6.1e-44	97.0
AWV27539.1\|3150690_3151206_-\|tail	phage major tail tube protein	A0A1S6L002	Salmonella_phage	1.1e-90	97.1
AWV27540.1\|3151215_3152388_-\|tail	phage tail protein	A0A1S6KZY7	Salmonella_phage	9.5e-210	93.6
AWV27541.1\|3152654_3153719_+	hypothetical protein	NA	NA	NA	NA
AWV27542.1\|3153750_3154116_-\|tail	phage tail protein	A0A0M4S6V4	Salmonella_phage	2.6e-33	61.9
AWV27543.1\|3155713_3156319_-\|tail	phage tail protein I	E5G6N9	Salmonella_phage	7.8e-115	97.5
AWV27544.1\|3156311_3157220_-\|plate	baseplate assembly protein	E5G6N8	Salmonella_phage	9.5e-149	93.7
AWV27545.1\|3157206_3157566_-\|plate	baseplate assembly protein	E5G6N7	Salmonella_phage	2.6e-57	95.0
AWV27546.1\|3157562_3158141_-\|plate	baseplate assembly protein	E5G6N6	Salmonella_phage	8.0e-101	92.2
AWV27547.1\|3158217_3159378_+	hypothetical protein	NA	NA	NA	NA
AWV27548.1\|3159355_3159802_-	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	2.4e-60	83.1
AWV27549.1\|3159794_3160226_-\|tail	phage tail protein	A0A1S6KZY0	Salmonella_phage	3.2e-70	92.3
AWV27550.1\|3160191_3160392_-	hypothetical protein	A0A1S6KZX6	Salmonella_phage	3.8e-26	86.4
AWV27551.1\|3160321_3160750_-	hypothetical protein	A0A1S6KZX8	Salmonella_phage	6.2e-58	87.1
AWV27552.1\|3160746_3161262_-	glycoside hydrolase	E5G6N1	Salmonella_phage	1.9e-74	78.8
AWV27553.1\|3161242_3161458_-	hypothetical protein	E5G6N0	Salmonella_phage	8.5e-32	97.2
AWV27554.1\|3161461_3161665_-\|tail	phage tail protein	E5G6M9	Salmonella_phage	2.1e-32	94.0
AWV27555.1\|3161664_3162129_-\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	7.4e-81	94.2
AWV27556.1\|3162222_3162873_-	hypothetical protein	A0A1S6KZX1	Salmonella_phage	6.0e-113	97.7
AWV27557.1\|3162876_3163974_-\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	2.6e-177	90.1
AWV27558.1\|3163990_3164824_-\|capsid	capsid protein	A0A1S6KZW9	Salmonella_phage	9.1e-122	92.4
AWV27559.1\|3164966_3166733_+	oxidoreductase	A0A1S6KZW3	Salmonella_phage	0.0e+00	95.1
AWV27560.1\|3166732_3167767_+\|portal	phage portal protein	E5G6M3	Salmonella_phage	3.7e-173	91.0
AWV27561.1\|3167811_3169572_-	ribonuclease H	NA	NA	NA	NA
AWV27562.1\|3170037_3170226_-	hypothetical protein	E5G6M0	Salmonella_phage	5.7e-24	91.7
AWV27563.1\|3170363_3170591_+	hypothetical protein	NA	NA	NA	NA
AWV27564.1\|3170610_3173019_-	endonuclease	A0A1S6L028	Salmonella_phage	0.0e+00	95.1
AWV27565.1\|3173009_3173867_-	DNA adenine methylase	A0A1S6L011	Salmonella_phage	6.4e-131	81.4
AWV27566.1\|3173863_3174091_-	hypothetical protein	A0A1S6L007	Salmonella_phage	4.3e-34	90.7
AWV27567.1\|3174090_3174324_-	hypothetical protein	A0A1S6L021	Salmonella_phage	1.2e-31	93.5
AWV29219.1\|3174391_3174733_-	hypothetical protein	E5G6L5	Salmonella_phage	6.4e-50	86.7
AWV27568.1\|3174811_3175060_+	hypothetical protein	NA	NA	NA	NA
AWV27569.1\|3175103_3175439_-	fil domain protein	A0A1S6L005	Salmonella_phage	4.6e-24	89.3
AWV27570.1\|3175446_3175956_-	hypothetical protein	A0A1S6L008	Salmonella_phage	1.6e-81	92.9
AWV27571.1\|3175988_3176210_-	regulator	NA	NA	NA	NA
AWV27572.1\|3176335_3176896_+	phage repressor protein	A0A1S6KZZ7	Salmonella_phage	1.2e-40	46.4
AWV27573.1\|3176969_3178247_+	hypothetical protein	NA	NA	NA	NA
AWV27574.1\|3178330_3179350_+\|integrase	integrase	A0A218M4I3	Erwinia_phage	1.0e-103	56.4
AWV27575.1\|3180469_3181267_+	short-chain dehydrogenase	NA	NA	NA	NA
3180343:3180367	attR	NA	NA	NA	NA
AWV27576.1\|3181253_3181814_-	DNA-binding transcriptional regulator	NA	NA	NA	NA
AWV27577.1\|3181899_3183108_+	MFS transporter	NA	NA	NA	NA
AWV27578.1\|3183107_3183923_+	sugar-phosphatase	NA	NA	NA	NA
AWV27579.1\|3184030_3184312_+	hypothetical protein	NA	NA	NA	NA
AWV27580.1\|3184529_3185762_-	multidrug transporter MdfA	NA	NA	NA	NA
AWV27581.1\|3186059_3186668_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
AWV27582.1\|3186732_3187491_+	DNA-binding transcriptional repressor DeoR	A0A077SK06	Escherichia_phage	3.3e-14	28.3
AWV29220.1\|3187536_3188739_-	serine-type D-Ala-D-Ala carboxypeptidase	B6DZZ7	Stx2-converting_phage	2.9e-97	47.1
AWV27583.1\|3189067_3189694_+	glutathione S-transferase family protein	NA	NA	NA	NA
AWV27584.1\|3189699_3190797_-	oxidoreductase	NA	NA	NA	NA
AWV27585.1\|3190899_3191283_-	transcriptional regulator	NA	NA	NA	NA
AWV27586.1\|3191503_3192430_+	LysR family transcriptional regulator	NA	NA	NA	NA
AWV27587.1\|3192462_3194913_-	glycogen phosphorylase	A0A140XAG6	Dickeya_phage	1.3e-22	74.6
AWV27588.1\|3194964_3195162_-	glycine cleavage system protein T	NA	NA	NA	NA
AWV27589.1\|3195381_3196689_+	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
AWV27590.1\|3196781_3197693_-	glutathione ABC transporter permease GsiD	NA	NA	NA	NA
AWV27591.1\|3197695_3198616_-	glutathione ABC transporter permease GsiC	NA	NA	NA	NA
AWV27592.1\|3198662_3200201_-	glutathione ABC transporter substrate-binding protein GsiB	NA	NA	NA	NA
AWV27593.1\|3200229_3202101_-	glutathione ABC transporter ATP-binding protein GsiA	G9BWD6	Planktothrix_phage	1.1e-13	29.1
AWV27594.1\|3202087_3203053_-	beta-aspartyl-peptidase	NA	NA	NA	NA
AWV27595.1\|3203244_3204033_-	aminoglycoside resistance protein	NA	NA	NA	NA
AWV27596.1\|3204207_3205443_+	molybdopterin molybdenumtransferase MoeA	NA	NA	NA	NA
AWV27597.1\|3205442_3206192_+	molybdopterin-synthase adenylyltransferase MoeB	NA	NA	NA	NA
AWV27598.1\|3206240_3207170_-\|transposase	ISNCY family transposase	Q2A0A7	Sodalis_phage	3.0e-65	48.3

DBSCAN-SWA_6

3220965 : 3248057

Cronobacter_phage(87.5%)

head,capsid,terminase,portal,tail,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWV27608.1\|3220965_3222669_-	hypothetical protein	F1BUJ7	Cronobacter_phage	1.5e-224	80.2
AWV27609.1\|3222668_3223214_-	hypothetical protein	F1BUJ9	Cronobacter_phage	7.4e-64	72.0
AWV27610.1\|3223185_3223911_-	hypothetical protein	F1BUK1	Cronobacter_phage	8.9e-65	53.9
AWV27611.1\|3223900_3224437_-\|tail	phage tail protein	F1BUK2	Cronobacter_phage	2.4e-22	37.0
AWV27612.1\|3224448_3226545_-\|tail	phage tail protein	F1BUK3	Cronobacter_phage	1.0e-145	77.8
AWV27613.1\|3226555_3227149_-	hypothetical protein	F1BUK5	Cronobacter_phage	3.1e-92	82.6
AWV27614.1\|3227135_3228320_-	hypothetical protein	F1BUK6	Cronobacter_phage	2.6e-183	81.4
AWV27615.1\|3228316_3228646_-	hypothetical protein	F1BUK8	Cronobacter_phage	9.3e-38	68.8
AWV27616.1\|3228642_3230703_-\|tail	phage tail tape measure protein	F1BUK9	Cronobacter_phage	5.3e-272	69.5
AWV27617.1\|3230890_3231157_-	hypothetical protein	A5X9I7	Aeromonas_virus	3.0e-18	57.3
AWV27618.1\|3231134_3231323_-	hypothetical protein	F1BUL1	Cronobacter_phage	2.0e-21	75.8
AWV27619.1\|3231252_3231633_-	hypothetical protein	F1BUL2	Cronobacter_phage	1.8e-29	64.0
AWV27620.1\|3231632_3231974_-	hypothetical protein	F1BUL3	Cronobacter_phage	6.9e-52	94.1
AWV27621.1\|3231960_3232263_-\|holin	holin	A0A0M5M1H1	Salmonella_phage	1.4e-19	55.3
AWV27622.1\|3232273_3232729_-\|tail	phage tail protein	F1BUL4	Cronobacter_phage	5.9e-59	72.8
AWV27623.1\|3232725_3233853_-\|tail	phage tail protein	F1BUL5	Cronobacter_phage	3.1e-173	81.6
AWV27624.1\|3233849_3234557_-	hypothetical protein	F1BUL6	Cronobacter_phage	1.4e-99	75.2
AWV27625.1\|3234553_3235060_-\|tail	phage tail protein	F1BUL7	Cronobacter_phage	6.2e-65	68.7
AWV27626.1\|3235056_3235560_-\|head	head completion protein	F1BUL8	Cronobacter_phage	1.2e-63	82.7
AWV27627.1\|3235605_3236307_-\|terminase	terminase	F1BUM0	Cronobacter_phage	1.2e-90	69.4
AWV27628.1\|3236310_3237333_-\|capsid	major capsid protein	F1BUM2	Cronobacter_phage	1.0e-159	81.8
AWV27629.1\|3237394_3238198_-\|capsid	phage capsid protein	F1BUM4	Cronobacter_phage	1.3e-80	56.8
AWV27630.1\|3238359_3240135_+\|terminase	terminase	F1BUM5	Cronobacter_phage	4.2e-294	86.3
AWV27631.1\|3240131_3241193_+\|portal	phage portal protein	F1BUM7	Cronobacter_phage	7.9e-163	77.8
AWV27632.1\|3241189_3241513_+	transcriptional regulator	F1BUM8	Cronobacter_phage	4.7e-50	93.3
AWV27633.1\|3241486_3241693_-	hypothetical protein	NA	NA	NA	NA
AWV27634.1\|3241812_3243828_-	replication protein A	F1BUM9	Cronobacter_phage	2.2e-299	75.0
AWV27635.1\|3243829_3244042_-	hypothetical protein	NA	NA	NA	NA
AWV27636.1\|3244038_3244908_-	adenine methylase	F1BUN1	Cronobacter_phage	1.3e-131	81.7
AWV27637.1\|3244897_3245227_-	hypothetical protein	Q7Y4B7	Escherichia_virus	6.7e-12	46.4
AWV27638.1\|3245217_3245451_-	hypothetical protein	NA	NA	NA	NA
AWV27639.1\|3245518_3245920_-	hypothetical protein	F1BUN2	Cronobacter_phage	2.0e-50	67.7
AWV27640.1\|3245919_3246348_-	hypothetical protein	F1BUN5	Cronobacter_phage	1.6e-26	53.3
AWV27641.1\|3246337_3246565_-	hypothetical protein	NA	NA	NA	NA
AWV27642.1\|3246574_3247078_-	hypothetical protein	F1BUN6	Cronobacter_phage	4.5e-60	72.5
AWV27643.1\|3247108_3247330_-	regulator	NA	NA	NA	NA
AWV27644.1\|3247475_3248057_+	phage repressor protein	A0A218M4J1	Erwinia_phage	1.8e-31	39.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP021963

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection