CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP029480	Arcticibacterium luteifluviistationis strain SM1504 chromosome, complete genome	4 crisprs	cas3,DEDDh,RT,cas2,cas1,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,WYL,csa3,PD-DExK,Cas9_archaeal	0	6	1	0

1. CP029480

CRISPR-Cas detection and classification

Crispr_ID: CP029480_1

• CRISPR_ID: CP029480_1
• CRISPR_location: 1324128-1324989
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 12 spacers
• Cas_protein_info: cas2,cas1,RT,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10

Consensus repeat of CP029480_1

Consensus_repeat	Method
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAACG	CRT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	CRISPRCasFinder
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	PILER-CR

spacers of CP029480_1

>1.1|1324164|31|CP029480|CRT
TCTGAATATGGAAGACTTTTACAATTGTCAC
>1.2|1324231|32|CP029480|CRT
GTAATCCAATTTACTGACCAAAATCCAATTCT
>1.3|1324299|32|CP029480|CRT
GTAATCCAAATTACTGACCAAAATCCAATTCT
>1.4|1324367|34|CP029480|CRT,CRISPRCasFinder
AAGGAAGAGACAAGTTCTCTGAACTACTTACAAT
>1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR
AAATTTGTCAAAAAACAAGGAGAGAAAATTAAA
>1.6|1324506|35|CP029480|CRT,CRISPRCasFinder,PILER-CR
AAGCACAAACAGACCCTCTATGGCCGCTTAGAATC
>1.7|1324577|33|CP029480|CRT,CRISPRCasFinder,PILER-CR
ATTAAGAAAATTATGGAGTAATTCATGAAAAAT
>1.8|1324646|35|CP029480|CRT,CRISPRCasFinder,PILER-CR
GGTGGAAATTAGAATACTAAAGTTTAACACTTTAT
>1.9|1324717|32|CP029480|CRT,CRISPRCasFinder,PILER-CR
TATAGAAGGGAATATACCTTCAAAAAAAGTAT
>1.10|1324785|34|CP029480|CRT,CRISPRCasFinder,PILER-CR
AATTAAAGGCTTTGAAATAAGTCTAAAAATAAAA
>1.11|1324855|29|CP029480|CRT,CRISPRCasFinder,PILER-CR
TATAATATAGAAATAGGCAAAAGACAGTT
>1.12|1324920|34|CP029480|CRT,CRISPRCasFinder,PILER-CR
TTTTTACTGAGTATCAACAATGATATTTCAGCTC

CRISPR arrays and Neighbor proteins around CP029480_1

CRISPR arrays

The CRISPR arrays of CP029480_1

>merge|CP029480|1|1324128-1324989|CRT,CRISPRCasFinder,PILER-CR
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAACTCTGAATATGGAAGACTTTTACAATTGTCACGTCTAAGTGGAGTAGAAATCCTTAATCAACTGAACGGTAATCCAATTTACTGACCAAAATCCAATTCTGTCTAAGTGGAGTAGAAATCCTTAATCAACTGAACGGTAATCCAAATTACTGACCAAAATCCAATTCTGTCTAAGTGGAGTATAAAATCCTTAATCAACTGAACAAGGAAGAGACAAGTTCTCTGAACTACTTACAATGTCTAAGTGGAGTATAAAATCCTTAATCAACTGAACAAATTTGTCAAAAAACAAGGAGAGAAAATTAAAGTCTAAGTGGAGTATAAAATCCTTAATCAACTGAACAAGCACAAACAGACCCTCTATGGCCGCTTAGAATCGTCTAAGTGGAGTATAAAATCCTTAATCAACTGAACATTAAGAAAATTATGGAGTAATTCATGAAAAATGTCTAAGTGGAGTATAAAATCCTTAATCAACTGAACGGTGGAAATTAGAATACTAAAGTTTAACACTTTATGTCTAAGTGGAGTATAAAATCCTTAATCAACTGAACTATAGAAGGGAATATACCTTCAAAAAAAGTATGTCTAAGTGGAGTATAAAATCCTTAATCAACTGAACAATTAAAGGCTTTGAAATAAGTCTAAAAATAAAAGTCTAAGTGGAGTATAAAATCCTTAATCAACTGAACTATAATATAGAAATAGGCAAAAGACAGTTGTCTAAGTGGAGTATAAAATCCTTAATCAACTGAACTTTTTACTGAGTATCAACAATGATATTTCAGCTCGTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC

>CP029480|1|1|1324128-1324989|CRT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	TCTGAATATGGAAGACTTTTACAATTGTCAC
GTCTAAGTGGAGTAGAAATCCTTAATCAACTGAACG	GTAATCCAATTTACTGACCAAAATCCAATTCT
GTCTAAGTGGAGTAGAAATCCTTAATCAACTGAACG	GTAATCCAAATTACTGACCAAAATCCAATTCT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	AAGGAAGAGACAAGTTCTCTGAACTACTTACAAT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	AAATTTGTCAAAAAACAAGGAGAGAAAATTAAA
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	AAGCACAAACAGACCCTCTATGGCCGCTTAGAATC
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	ATTAAGAAAATTATGGAGTAATTCATGAAAAAT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	GGTGGAAATTAGAATACTAAAGTTTAACACTTTAT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	TATAGAAGGGAATATACCTTCAAAAAAAGTAT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	AATTAAAGGCTTTGAAATAAGTCTAAAAATAAAA
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	TATAATATAGAAATAGGCAAAAGACAGTT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	TTTTTACTGAGTATCAACAATGATATTTCAGCTC
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC

>CP029480|1|1|1324331-1324989|CRISPRCasFinder
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	AAGGAAGAGACAAGTTCTCTGAACTACTTACAAT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	AAATTTGTCAAAAAACAAGGAGAGAAAATTAAA
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	AAGCACAAACAGACCCTCTATGGCCGCTTAGAATC
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	ATTAAGAAAATTATGGAGTAATTCATGAAAAAT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	GGTGGAAATTAGAATACTAAAGTTTAACACTTTAT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	TATAGAAGGGAATATACCTTCAAAAAAAGTAT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	AATTAAAGGCTTTGAAATAAGTCTAAAAATAAAA
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	TATAATATAGAAATAGGCAAAAGACAGTT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	TTTTTACTGAGTATCAACAATGATATTTCAGCTC
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC

>CP029480|1|1|1324401-1324989|PILER-CR
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	AAATTTGTCAAAAAACAAGGAGAGAAAATTAAA
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	AAGCACAAACAGACCCTCTATGGCCGCTTAGAATC
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	ATTAAGAAAATTATGGAGTAATTCATGAAAAAT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	GGTGGAAATTAGAATACTAAAGTTTAACACTTTAT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	TATAGAAGGGAATATACCTTCAAAAAAAGTAT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	AATTAAAGGCTTTGAAATAAGTCTAAAAATAAAA
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	TATAATATAGAAATAGGCAAAAGACAGTT
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC	TTTTTACTGAGTATCAACAATGATATTTCAGCTC
GTCTAAGTGGAGTATAAAATCCTTAATCAACTGAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP029480.1|AWV97679.1|1329223_1330258_-|hypothetical-protein	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl|CDD|273866
CP029480.1|AWV97665.1|1306085_1307003_+|hypothetical-protein	unknown	unknown	unknown
CP029480.1|AWV97668.1|1314603_1316268_+|hypothetical-protein	unknown	unknown	unknown
CP029480.1|AWV97667.1|1309058_1312277_-|SusC/RagA-family-TonB-linked-outer-membrane-protein	unknown	unknown	gnl|CDD|274948
CP029480.1|AWV97669.1|1317037_1318429_+|hypothetical-protein	unknown	unknown	gnl|CDD|271185
CP029480.1|AWW00817.1|1312971_1314129_+|glucuronyl-hydrolase	unknown	unknown	gnl|CDD|369381
CP029480.1|AWV97675.1|1325393_1326380_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187766
CP029480.1|AWV97674.1|1325103_1325397_-|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|378256
CP029480.1|AWV97672.1|1320608_1323065_+|hypothetical-protein	unknown	unknown	gnl|CDD|132299
CP029480.1|AWV97683.1|1333034_1335749_+|hypothetical-protein	unknown	unknown	gnl|CDD|378942
CP029480.1|AWV97670.1|1318543_1319308_+|hypothetical-protein	unknown	unknown	gnl|CDD|238612
CP029480.1|AWV97677.1|1327431_1328106_-|hypothetical-protein	cas6	cls000004_cas6_CAS-I:CAS-III	gnl|CDD|379957
CP029480.1|AWV97673.1|1323078_1324029_+|hypothetical-protein	unknown	unknown	unknown
CP029480.1|AWV97678.1|1328102_1329224_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	COG1332_csm5gr7_CAS-III-A	gnl|CDD|273863
CP029480.1|AWV97682.1|1331374_1332853_-|hypothetical-protein	cas10	cd09680_cas10_CAS-III	gnl|CDD|187811
CP029480.1|AWV97676.1|1326381_1327422_-|hypothetical-protein	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|239569
CP029480.1|AWV97681.1|1330907_1331378_-|hypothetical-protein	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl|CDD|367635
CP029480.1|AWV97666.1|1307246_1309028_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|369630
CP029480.1|AWV97680.1|1330239_1330911_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187815
CP029480.1|AWV97671.1|1319352_1320627_+|hypothetical-protein	unknown	unknown	gnl|CDD|378409

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP029480.1|AWV97679.1|1329223_1330258_-|hypothetical-protein	csm4gr5	COG1567_csm4gr5_CAS-III-A	1.9e-26	87.7	0.5
CP029480.1|AWV97682.1|1331374_1332853_-|hypothetical-protein	cas10	cd09680_cas10_CAS-III	6.5e-50	165.0	15.6
CP029480.1|AWV97676.1|1326381_1327422_-|hypothetical-protein	RT	pfam00078_RT_CAS-I:CAS-III	1.9e-21	71.4	0.7
CP029480.1|AWV97677.1|1327431_1328106_-|hypothetical-protein	cas6	cls000004_cas6_CAS-I:CAS-III	2.3e-12	41.7	0.4
CP029480.1|AWV97678.1|1328102_1329224_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	COG1332_csm5gr7_CAS-III-A	9.9e-18	59.6	4.0
CP029480.1|AWV97675.1|1325393_1326380_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	2.1e-68	225.4	0.1
CP029480.1|AWV97674.1|1325103_1325397_-|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	2.4e-12	41.8	0.0
CP029480.1|AWV97681.1|1330907_1331378_-|hypothetical-protein	csm2gr11	pfam03750_csm2gr11_CAS-III-A	4.4e-12	41.2	2.6
CP029480.1|AWV97680.1|1330239_1330911_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	1.3e-50	166.8	0.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP029480.1|AWV97679.1|1329223_1330258_-|hypothetical-protein	gnl|CDD|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	4.24553e-14
CP029480.1|AWV97682.1|1331374_1332853_-|hypothetical-protein	gnl|CDD|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	4.37955e-25
CP029480.1|AWV97667.1|1309058_1312277_-|SusC/RagA-family-TonB-linked-outer-membrane-protein	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
CP029480.1|AWV97669.1|1317037_1318429_+|hypothetical-protein	gnl|CDD|271185	cd01185, INTN1_C_like, Integrase IntN1 of Bacteroides mobilizable transposon NBU1 and similar proteins, C-terminal catalytic domain. IntN1 is a tyrosine recombinase for the integration and excision of Bacteroides mobilizable transposon NBU1 from the host chromosome. IntN1 does not require strict homology between the recombining sites seen with other tyrosine recombinases. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.29963e-22
CP029480.1|AWW00817.1|1312971_1314129_+|glucuronyl-hydrolase	gnl|CDD|369381	pfam07470, Glyco_hydro_88, Glycosyl Hydrolase Family 88. Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.	3.52028e-17
CP029480.1|AWV97675.1|1325393_1326380_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	3.39836e-73
CP029480.1|AWV97674.1|1325103_1325397_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	2.39788e-05
CP029480.1|AWV97672.1|1320608_1323065_+|hypothetical-protein	gnl|CDD|132299	TIGR03255, PhnV, 2-aminoethylphosphonate ABC transport system, membrane component PhnV. This membrane component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.	0.00098625
CP029480.1|AWV97683.1|1333034_1335749_+|hypothetical-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	1.53302e-31
CP029480.1|AWV97670.1|1318543_1319308_+|hypothetical-protein	gnl|CDD|238612	cd01285, nucleoside_deaminase, Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on the substrate. The functional enzyme is a homodimer. Cytosine deaminase catalyzes the deamination of cytosine to uracil and ammonia and is a member of the pyrimidine salvage pathway. Cytosine deaminase is found in bacteria and fungi but is not present in mammals; for this reason, the enzyme is currently of interest for antimicrobial drug design and gene therapy applications against tumors. Some members of this family are tRNA-specific adenosine deaminases that generate inosine at the first position of their anticodon (position 34) of specific tRNAs; this modification is thought to enlarge the codon recognition capacity during protein synthesis. Other members of the family are guanine deaminases which deaminate guanine to xanthine as part of the utilization of guanine as a nitrogen source.	1.62363e-23
CP029480.1|AWV97677.1|1327431_1328106_-|hypothetical-protein	gnl|CDD|379957	pfam17262, DUF5328, Family of unknown function (DUF5328). This family of unknown function can be found in Bacteria and Archaea. Some of the proteins in this family are annotated in UniProt as putative DNA repair proteins.	2.255e-10
CP029480.1|AWV97678.1|1328102_1329224_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl|CDD|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	5.53444e-12
CP029480.1|AWV97676.1|1326381_1327422_-|hypothetical-protein	gnl|CDD|239569	cd03487, RT_Bac_retron_II, RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA branches out from a small ssRNA molecule via a 2'-5'phosphodiester linkage. Bacterial retron RTs produce cDNA corresponding to only a small portion of the retron genome.	2.49199e-54
CP029480.1|AWV97681.1|1330907_1331378_-|hypothetical-protein	gnl|CDD|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	0.000439915
CP029480.1|AWV97666.1|1307246_1309028_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	3.37216e-46
CP029480.1|AWV97680.1|1330239_1330911_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl|CDD|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	5.41144e-55
CP029480.1|AWV97671.1|1319352_1320627_+|hypothetical-protein	gnl|CDD|378409	pfam10137, TIR-like, Predicted nucleotide-binding protein containing TIR-like domain. Members of this family of bacterial nucleotide-binding proteins contain a TIR-like domain. Their exact function has not, as yet, been defined.	2.07618e-14

Protein sequences

>CP029480.1|AWV97673.1|1323078_1324029_+|hypothetical-protein
MEQIDSKLNKLMTRLDLEAEHVKRKRFKTTWIAGIICGVLAVISFAIALPFHSFIHNKHSLLGLATLEFSLILISFILLGRFAPKFKNKFLTLRRNAEYLRAIDAVHNSGLKVSGLDIKEPNAFFKISEEVSIIEKEILTSSLQSQVDKQSTDAINEKVTDFLDQQIAYHKTKRIKKYEREYHRNEVFLNLIKALFLIAISVKFALELSHHFHYQLTPSWISPEWLLALTQAGVISFPPIYAAIEGVNYFSEYRRNIKLSKKMVDELIDFKKKLALHDLNQKENLETLGKELRQLLEEENSDWAFRYNERIVEAKI
>CP029480.1|AWV97672.1|1320608_1323065_+|hypothetical-protein
MGHKTIALTGHIDLILDDKPIIYDKLRAKFIELLNVNKSIVLLIGKAEGADQIAREIAVELGITIVDLDKQLKPIQGEPSGEYYRRQGEYLVKNATMLIALWDGIFSGKLGGTSDIVKMALDASSEKTIHHLICPRESNHFPVSNFAAEIINLKSKTFNRIPFTVHYSWVQFNTSVKRKSTWWTSLVSNAIKSVQSGLFWIYLLPILLILATLGLGSWGFTIKNPCDTALNHFFNALNLITFDGSVIDGKSNLQIDISRILGLLLVLSAFIYGFYIALEKQRIKLKRRLWRKDFYLISGLTEKSIRLAKNLANHSQVVLIYKNDETSQTNSLVNNDKIITIHADSSSKRILKGAYAFDAKKTFLMDEDETQNIRTAQELDSLSKTEKKTINSLFVHVNKDENRKLLQQTLSYQTLIKSHIFNTEENTVRRLLLLYPPDRFHQNEGTETPAITCVNIIIGWEELSQQLVLAFLRQGHFTHDKKLKIIILCKDSETEHTKFLNNYPLFDATLHEFKSIKQYTWGNIELIFKELPNSSYEWLKEDNSIITSIKKQNIINLYFTFKNSIESSAILDNILPKVNTLKKTNNCNLQAFYFYNFPDKSEENQTEEHFNKKAPDVFLKCFGNYRDECSLDYLQNSNIDTLAKLINAKYSGIAIDQITLKENKTITTTAIEKAWLNCSEKDKSSSRQAADHLWVKLRLLWPLINWKFDPITFEPDGEVKNILYNKKNIQIFAEIEHRRWCAEQLLWGYSPITEDASSKAYLEMTEKWNNDKAWKKSQQAELKHIDLVPFEELTMHEIQKDIEQLLAIPEFLRNVIKP
>CP029480.1|AWV97671.1|1319352_1320627_+|hypothetical-protein
MQKNSRTLDKFHDGDTLNSPEGRLVKNLRAKKQKPSIFIGCSSEAHHIAREIQSFFNKSLFEVDTWKMSIFGGMHKDGTTLTISEHLKNFTDIYDFAIFLFVPDEEIQTKTRIIAGTQKVAESKGVKHNVIFEFGMFLGRLGAKRSIVLYHNGQEVRDFIELFFTDLKDDIGSPINDTKITNSFKLELYPFEGEYVDYINAEGTKEHSFNNDNLKKIVTDLQKKILKTQNEVDISFLPSTSLAFGYYNNFIKRLYEALKVLLKSNTDLKKLETDNRDISELILKKKEVIFYIIIPKKISEAKYNSIDKFKDKGFLVDKSLGVQKGRPVTIYVGKNGLSQTSEKLEIYDFPTTITSSIDAIKMVNKDKDIRELLAEKEKRNFIKVMESILAKNGTKIKNKNTIFRIEFIDLAKFKRQAEIWVTKQ
>CP029480.1|AWV97670.1|1318543_1319308_+|hypothetical-protein
MKKTIPVLCLSLLLFGCQTNKKLANTIMSPLNQVEEISEMQNERDEIFLLLAYSLVYNDWQPESVPRFERRGYNIGTVLVNAQNEPVYAGLNAINSTDNATQHGEVRAITGYLEENGGYNLKDFTVYTTLEPCIMCAGMITMTNVKRVVIGQKDFDYSHAFERLAIDTRAVEGFPPYPRKSDIYYPNLSVSQKLDIAFANFLKTEEEKYLARFLSSEIAKSIFKEAENEFLNYQVKFSENQDILTKTREFYIKS
>CP029480.1|AWV97669.1|1317037_1318429_+|hypothetical-protein
MPTVKIFLDTRNNSENKGIIKVSITHNRRQRLYTTGIKIDIDEYKNFNKGIGKDGISGRIKNPRFIDLYEVLYDSFKDGSETVSGYHKRAVEIIDKLGSQFTFEAFKYEFDNYSKKHLYNTSNENDIFIVADGIINKLWNEDRIANSNSYKTAIQSLKRFLREMDRHVRAELLLPQPPKDKTKPLTLNFEQVTVNFLNHYEDWMLKYGRKSQKKFGPGYPASRTTVGIYVRQIRAVFNEAISRKITDNYPFGKRAYVIPAGRNIKKALTKEEINKILNYVPESNTLEARSHAVWVFSYLGNGINVSDICRLKQSDYDVNNRKITFVRQKTKRTNKSNLKEIEIYLADEHISIIQNFGNSRRNGNAYLLNLLKPEMTEVNIIKTIQQIILITNKWMKKIATKLGISSPVTTYVARHSFATILLQSEAPIAFISKALGHSSLATTETYLGSFEDDKARGYMAALR
>CP029480.1|AWV97668.1|1314603_1316268_+|hypothetical-protein
MQKIPLCLTILFVGYLSLSCNGPSKSEIEFTPEQNTAFEQAQANGILVNTGLERCRLFVKDWLAQADSSTGLIPKNLYTDLDIWNAKDAAADNYPFMVLTAAITDKELFEGRMLDMLKNETRLTSRIDRMPDTYSFSKKGFDNPEADLESILFGSSEYIKDGLLPLTEWLGKSPWSERMIGILDDMWKHAPVETKFGKIVSTNVEENGEMLQVLSRVYWMTGEQKYLDWAIRLGDYYLLGDQHPTRDFTGLRLRDHGCEVVSGLSELYVTTHYASKGKKAEYQPHIHEMLDRILEVGRNKDGLFYDAINPQTGAILKERVADNFGYTFNAFYSVYQIDAVEAYRTATLKGLSVLNDKYRNYDWEDGSSDGYADAIEGALNLYAREPIASTAAWIDSETQVMWSLQDKSLRPNTSQWNSSGVIEGWHGDGNFARTTIMYCLWKTQGVTAYPWRSDIQIGAVKENGDLLISLNVEQDWEGVLKFDTPRHQTIMHMPSDWPRINQFPEWFTLEKDKNYEMINYTEQSEQSFSYQKLKEGIPLSLKKGVHKFIVKTAS
>CP029480.1|AWW00817.1|1312971_1314129_+|glucuronyl-hydrolase
MLACTSPTEETQSDQKDIELNKVLDNAAQKTKMTASALTKVDSFPRNISEGKTNWNLVDVKDWCSGFWPGVLWYAYEASGDEVLKEDAIRFTLPLKEIAYSPAENHDIGFMVNSSYGNAYRLTGNEEYKEVLIAAANNLATLYDPKVGTILSWPSQVENFQYNTIIDNMINLELLFWASKNGGGENLYDIAKSHAQKTMEHLVRPDSSLYHVGSFDQKTGEFLRGYTHQGYAHESMWARGQTWGIYGFSVAYRETADEEFLKTAIKLADHYIKRLPEDGIPFWDFDDPAIPNAPKDASAAAVAASGMLELSGLVKDPALKEKYYKAAESYIAKLATSEYLSGDTNQAILLHSTGHYPHNSEIDMPIIYADYYFMEALLRLKKSKD
>CP029480.1|AWV97667.1|1309058_1312277_-|SusC/RagA-family-TonB-linked-outer-membrane-protein
MTKFKHYQRNLNHFLSLFWVIGFLTCGVAAPSFAAEKITDINARVTGKVVASSDNLGMPGVNVLVKGTQKGTFTDGDGNYTIDNVDANSTLVFSFIGFESQEVTVGSQTVINVTLQDDERLLDEVIVVGYGTAKKETLTGSVEQVTSEAFEDLAVGSPALALQGRTPGLVVSRSSSRPGDEGVSFLIRGASSINGISPLIVIDGIPSINASSFNDMNPNDIESVSVLKGGSASVYGSRAAGGVILVTTKKGKGDVKVELSSVFRMGTIGIRPPSPTMAEYGQLYLAAVDEDLASNKPPRYFFWNDRPTLERIASGEEGYYDLPINGNVWLGNSAKFDEMFGNSASNQTNLSVSGGTAKSNYRISAGYDKNVGGLKVADDTADKYNFSANYGIDISDRLSLNTNITYFKNSFSGPAAGLAREAATWDAPLFPSYNPDGQYYANFGGVNITGDRNAIAQVKDAGRENLTREQFKVSAQATYKLTDHLNLTGSYALSKQNSVWQRYAVSVPLYSWQGGFSNNINNTTFIEEGTGPNTADGNITYNNYKAVLNYTNSFGDHNVSGIVGIEAEKNILDEYYLRRNGFVDYGVYDINIGATDQLVSTSGGGSTWGAFGYIGRLNYDYKGKYLLELQGRRDGSSRFAEGSKWSNYGSVSAGWVLSKEDFLVDNDMISFLKIRGGYGELGSTSGIGDFGYLSTVGFGTTVFGQTNASQQATSRASSLFSSTTTWERIATTEFGVDFGLFGDKMFGSFDLYKKNNIGMLVRGILPQTLGTAAPFTNIGTLETKGWEAMLGWRNKIGKDLDLAISANMSDSRNEITKYDGAQSIVENLNAASAGRNILGKPINSFYLWETDGYFGSQEEVNAYYSSLNAGGILPSQTSNDALRPGDMRVVDSNGDGTLDTDDLTYMGDNATHYVYGLNFDLKYKNFDLSGFFQGVLNQQIYRTGYFAQPFQAEWQNQSNTWLGRTWTEDNTDAEFPRLTTQRGLSAWNYRSKDHILQNNRYLRLKSLIVGYNIRGVKLGKTSVDNIRIYLSGNDLFEFTSVKDGYDPEFRASTNESVYPFMRTWAAGLKISL
>CP029480.1|AWV97666.1|1307246_1309028_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKKIIQIIIPCLMVLFTSCEDKFIDLTPPASITDDVYYTEAEHFLTGSNRFYTNLIRWNDQGIYSGHGSDLVGYTEDGGMQEYSRGDTQAAAEDAYYSAPYTAIRDMNLLLARAEAYEGNDIGEYVAATKFHRAWQYFFLVQRFGGVTLVTEPLDVDSESLFGARNSRYEVVAQILADLDDAIAGLPTEQDIAGGDKGKISKWAAMAFKANVLLHEATWMKYVGTSTDGDGTSTGAGSAGFSESNINTYLQEAVTLTKTVMDNGGFELWNHNEELDNLSSNFLFNLEDGGSNPGGFDKATNKEFILYNKYDFTFRQAGTLVSHVYEGRMKPSRKMIDMFLCDDGLPIDQSPKFEGYANTPDEFQNRDYRMRAYFTYHKNLGEVPQNGDVVLNGTNNFGYFNSKFMSWKWGTDEAYRATTTEAYDMPLIRLAEVYLMYAEALYELNGSLSDAQMAESINLVKARAGLPAITNAFLSANNMDIKTEIRRERTIELYAESGSRFNDLKRWGIAEQELGETIYGAVIEGTVYEGNTALYDPAKYGYGEETTMTGVGQRRCLIVQPSGIRNFTKDDYLFPLPTSQVGLNDNLRQNAGY
>CP029480.1|AWV97665.1|1306085_1307003_+|hypothetical-protein
MGIAHKKQSIQDWITQQWVIVFGKKIDRTNHKWLLGPFGGTNGIGHKFIKQLAEKEHLVIDNKKIDKGLIKSIDQLNLSTDELNALSQDVIDFYENTSNYDLRLKAKWNPLFKGFGIWVRIIFSKRIEQLNVPIQNVEDSSGLTSEIIQLHDSKTNEVKRTIWLRAFKSTGQVVYSGVYEICTIPSGKTCIKAIFPLPNGNATVILTPKIGKNGELILDSAGQKIGDSGFYFLLKDSKGQLWTKFIKSFKDELVVRSVNDRITATQTLTLWNLRVLKFEYEIKKTTHKKVYGALHPAGYAPSTNR
>CP029480.1|AWV97674.1|1325103_1325397_-|CRISPR-associated-endonuclease-Cas2
MIYMVLYDITNNSIRKRIANRLIAEGYERLQLSVYLGNKNLKNDKKLWPVFCQWIEKDNGKMAIMKLPPTVVQNIHLEGEQMIDFEYLLGQKFCMFV
>CP029480.1|AWV97675.1|1325393_1326380_-|CRISPR-associated-endonuclease-Cas1
MQLIIDTANTTITVRNKCFYIKNAAVQKQISPLRLSSIAITTNCLLNTSAIKLAAHHQVPVLVFNNFGTIQARMTSPYFANLAMLRKKQLLFSISPQATTWIIKLLKKKSRQQVKTLKWLGRKKSSRRQEIEVAIDKMKSLEAKMEEIGSRPIANSKAVLMGIEGSISKIYFMALRVTVPPLFDFDKRSRRPALDFFNSGLNYLYGMTYSLVESGIFAKGLDPMIGIMHADQFKEPTLAFDLIEPIRPVMDRIWLGIIFQDILKKTDFIKKEQGYWLSKSGKRIVIKTFNEYTQQRVNYGGRVLRFKDHIYQEANSLGNYLLGNVELL
>CP029480.1|AWV97676.1|1326381_1327422_-|hypothetical-protein
MKKLYLADIEERSRRFLGCRTIDDLCCLGFVKNELLLHSLNISYYSFELRKKSGKMRQIESPNESLKKVLRQFNYYLQCVYYIHQTDASQGYIITPKKSKVCKSILENARVHLRNRFMLNIDFQDFFHQISFERLAKRLSETPFKFDTSTSKLLALLFTYKGRLPMGAPTSPVLSNLCVMKLDMEMSEWSKKNGVTYSRFVDDLTFSRDDSEFISDTYTEINHICLKHSLKVNPAKIKYFGEGSLRKVTGLILRETIDIEDGFYHELDKDFNRMKNLVEVVIINHGVKSNDEVQTFKKEIEGQINFIGMVEGYNSPIFNQYRQKLKAVMNPAEEVLSVRWTNFNYV
>CP029480.1|AWV97677.1|1327431_1328106_-|hypothetical-protein
MKAIPICTIRLLDVTINDEPDYKKMLLIGAFEKVQNSLKGEKVEGIEPELFHNQENKYSGIQLAAYKKTAEYTAIGETEVATLNFWYEQYLKSTGEAPQNIVLINETYVPAFIAYQQTYRVKTMLISDELAKELNNMTDKFARWDRLEKYLYGNLKRFMRHIGYEPGEQFLKVTIQDIMHYDTSKPVYHGQKKTALDIRFQCNFRLPQTLRLGQSTAIGYGRVS
>CP029480.1|AWV97678.1|1328102_1329224_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MNMPRKELYHHYQLEIETLSPVSIGCKSQLTSRGEYFLTGNKTHFIDQDGISEILYQNLTEEDKKEYLATVLNQGVDFNFTDFFKNKGISLEQIPISRSLSFIGDATLVNKNRLLKLHIKSGADENQNNSAYFPGSSLKGMIRTAMVYVHLKSHPELVSKFADKINNWSQIDKYELSKEWKVLEDSIIGKEANQLRIADTQNISDTDMAVYQVRREPLYFTESDSELDWLEECVDKGHKIFGALTYVQKNTKELACINFVPNILLGLNEWMTDMLDFEILEIEKSNMPKKEIVLAQLKSLIESSLQNNEYAAIARLGSGKTFMFNTILLLLEKGLRERILMTVLKTDSIKTRILCSHEKAPLKGWIKLNLRKL
>CP029480.1|AWV97679.1|1329223_1330258_-|hypothetical-protein
MDRTKVNIAKIFLEPYSRFHFGEYKIDHDLSLSDSSFFCHSDTLFSALINQCDRLNDDPDSFVEAFKEDEICISSVFYFFEKANCDPIYLLPKPVFIDKKVKISGAANKKQIQGVKFVSKAVWDKGFEYEKWNDIKSYVILQGNIVLTKEEYDQFGFNRNSALVKKNTRPKNQVRRPKKQARRKEDGIYYQTDVMVCSPAGVKAGIYFFYDVEDENTKRQFFNAVNVLCFSGLGGEQALLGRTPRKVPDFDQSLSFDSNKARLASISLFSPTDEAELAACTIYETSLRGGHKSGLSQNTDVVPMVMEGAEFTSSAKGCLVDLSLLPEKPIFRNGKVFLLPFESK
>CP029480.1|AWV97680.1|1330239_1330911_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MSKQHYKNPLVQKLIFSGEIHLISGLHIGGSTTDLDIGGIDNEVIKIIENGEETPYIPGSSLKGKMRSLLVKADGNIEIMDDSDEVKLLFGYPVDSNTTRLLFRDCYLLNDAHLETKTENSIERATGRSNPRDIERVGKGAVFVFDMVMDVYEKDIPDLKKHINLIRLGMELLEIDYLGGHGSRGAGKIAFKQVAYVPWNIDLINAEIIKDAPVAVYKWTEQK
>CP029480.1|AWV97681.1|1330907_1331378_-|hypothetical-protein
MKTNQKENSISTKVGDEKKATSFKESSNIPIFESYAIKIIGNRSLKESSELVKDIEEFIKYRTRKKGGEYMHYSQLRKVYQIVKNKAYKQDLSNFHMKVIPKLAYVQARHKGNGAAMAYVIREMAAAVEVGKLDTYTNFIEIMEAIVAYHKLHAKL
>CP029480.1|AWV97682.1|1331374_1332853_-|hypothetical-protein
MIKLQLFGIQDFIFNVKSKGAAAEIKGRSFYIKLLLEVSKKIIFETFQIDLKAQPSCIISNSGGYFILHLENIASDKLENCVSNLQAKLKNELKGTELKAVLAFTESTGNYKNDISLLNQNLQDKSYSLLSVFSDFNKFAPVVNQSKWTSVSTKVKNADGKGNVILEKNSLKGPLILGYSFSIKEEIEGIPLFRFMESYICKTQDGGYSTFQDLLWHGKGEPKLGVLLMDVDGLGQYFNSIISLATHKAFDEKLQVFFVNQLGKQIKFIKSKYNESVYVVTAGGDDSAFVGRWNNLLNLAMDIEISFKEEFKKEKLTISGALVIVNPKYPIIRAVKLAHEALKEAKYGYSTKGNFSLFGEIIYWYTLQKEIFSLRERFRKGMKSEKKTDSHGKSITTNKEVRLTRGLLARARQTAANLSSKNHLDLSDYFKLDYYLRENQKLRNEVGKEYRDYLIKAEKSTDELERRNYKMILPIAARLAELDTRGKKKKEK
>CP029480.1|AWV97683.1|1333034_1335749_+|hypothetical-protein
MLKTCISFLLLFISLSVSSQPSILSEWTLGNSASRQRNFSQALQHYERSFNLAVNAKNTLWQANVQTDISGAFFGLGKYSDGADACLKGLQILSQARFQPDTIEVKLYSALGANYKNLYRAQDAIEAYTKANALLEQNPKIKDLIPLYIAHHYYNQGIFWYKLCDYPRAKVSFENALEISEEIGLSSVSIKALNTLGSLYLYDGEYEKGVVIVQRALNFISDKKLNDKLRIAQGQFILGALLSANGKKEKAISQFNLVQANKSFLTKTLAGKNIYLLSILEEAKLLHPHKGLSLIHGIKASEIPNSLRARLSLTEGIFLSKLKLFKEAEDKLLSGLQLTNYSNKNTSEVNLTKEPSLSFEFFNCLADNKYLQFSITQDLHDLEKALDFELESVKIGEYLRTNQLTVESRIFFSERYFKRYQNSVKYALELYFFQNDKSSFYRLVDISERSKSYLVKNNNSLNKTKTITNDSLLLKLSAYQEYLSYLKNNKPENLNTIRDYTLKVNQVLQLLHKTTVPKVNLNYDALKANVPPDLLYVNYILLPDKLVMLTHSKNGWNFKQIDIDNKQLRKDISTLINAISKVPEPLEGFENMLAQDRLYEVFIAQLPEDIREFTRISINADKQFLGLSFDTLKDKKSGQLLIEKIAISYSNSLTDIINNPLKRKVGQNWNVFLPFSGNNGKSFKNLKPLPFSWKYARGIKGDFFLENDATKDIFIDKLSYDTSPLLVSTHASSKESEPYLLFNEKGDYNSKLYLSEIPHIPLKTSLMVLSACESNLGNRVNGLGLHSLGVSFRAAGCPTVLGSLWQAEDESTSLIISLFYRNVMKGLTIDKALQKAKLDYLKTDVGKRNDIPFYWANIQVIGSPHTVISQLGRFRIIFVAISSLLILLMLKVLFKKNLKRYFPF

Crispr_ID: CP029480_2

• CRISPR_ID: CP029480_2
• CRISPR_location: 1731748-1731849
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP029480_2

Consensus_repeat	Method
GTGTCTTAGCGGTTGAAAAACTAACCG	CRISPRCasFinder

spacers of CP029480_2

>2.1|1731775|48|CP029480|CRISPRCasFinder
CGAAGCTGCACATCGAGAAAGATTCGAAAGTAAAAGCTTAGCGTCTTC

CRISPR arrays and Neighbor proteins around CP029480_2

CRISPR arrays

The CRISPR arrays of CP029480_2

>merge|CP029480|2|1731748-1731849|CRISPRCasFinder
GTGTCTTAGCGGTTGAAAAACTAACCGCGAAGCTGCACATCGAGAAAGATTCGAAAGTAAAAGCTTAGCGTCTTCGTGTCTTAGCGATTGAAAAACTAACCG

>CP029480|2|2|1731748-1731849|CRISPRCasFinder
GTGTCTTAGCGGTTGAAAAACTAACCG	CGAAGCTGCACATCGAGAAAGATTCGAAAGTAAAAGCTTAGCGTCTTC
GTGTCTTAGCGATTGAAAAACTAACCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP029480.1|AWV97980.1|1725701_1726880_-|sodium:proton-antiporter	unknown	unknown	gnl|CDD|366411
CP029480.1|AWV97984.1|1729229_1729934_-|short-chain-dehydrogenase	unknown	unknown	gnl|CDD|235990
CP029480.1|AWV97986.1|1731961_1733461_+|glutamate--tRNA-ligase	unknown	unknown	gnl|CDD|234953
CP029480.1|AWV97988.1|1733847_1734627_+|TIGR00266-family-protein	unknown	unknown	gnl|CDD|376704
CP029480.1|AWV97976.1|1723558_1724338_-|short-chain-dehydrogenase	unknown	unknown	gnl|CDD|187602
CP029480.1|AWV97987.1|1733653_1733851_+|hypothetical-protein	unknown	unknown	unknown
CP029480.1|AWV97985.1|1730081_1731521_-|arylsulfatase	unknown	unknown	gnl|CDD|293750
CP029480.1|AWV97981.1|1727047_1727662_+|FAA-hydrolase-family-protein	unknown	unknown	gnl|CDD|223257
CP029480.1|AWV97977.1|1724519_1724816_-|hypothetical-protein	unknown	unknown	unknown
CP029480.1|AWV97989.1|1734773_1735628_+|xylose-isomerase	unknown	unknown	gnl|CDD|224007
CP029480.1|AWV97983.1|1728258_1729167_-|DUF4357-domain-containing-protein	unknown	unknown	gnl|CDD|198394
CP029480.1|AWV97990.1|1735679_1736282_-|SET-domain-containing-protein-lysine-N-methyltransferase	unknown	unknown	gnl|CDD|376403
CP029480.1|AWV97993.1|1740178_1741138_-|galactose-oxidase	unknown	unknown	gnl|CDD|276965
CP029480.1|AWV97994.1|1741163_1742576_-|hypothetical-protein	unknown	unknown	gnl|CDD|369642
CP029480.1|AWV97978.1|1724877_1725228_-|ribose-5-phosphate-isomerase	unknown	unknown	unknown
CP029480.1|AWV97979.1|1725237_1725648_-|hypothetical-protein	unknown	unknown	unknown
CP029480.1|AWV97992.1|1739736_1740192_-|DUF4440-domain-containing-protein	unknown	unknown	gnl|CDD|379209
CP029480.1|AWV97995.1|1742788_1743634_+|hypothetical-protein	unknown	unknown	gnl|CDD|273146
CP029480.1|AWV97982.1|1727777_1728074_-|addiction-module-antidote-protein,-HigA-family	unknown	unknown	gnl|CDD|274228
CP029480.1|AWV97991.1|1736425_1739359_-|helicase-SNF2	unknown	unknown	gnl|CDD|350770

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP029480.1|AWV97980.1|1725701_1726880_-|sodium:proton-antiporter	gnl|CDD|366411	pfam00999, Na_H_Exchanger, Sodium/hydrogen exchanger family. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.	1.26123e-05
CP029480.1|AWV97984.1|1729229_1729934_-|short-chain-dehydrogenase	gnl|CDD|235990	PRK07326, PRK07326, SDR family oxidoreductase.	1.11096e-137
CP029480.1|AWV97986.1|1731961_1733461_+|glutamate--tRNA-ligase	gnl|CDD|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
CP029480.1|AWV97994.1|1741163_1742576_-|hypothetical-protein	gnl|CDD|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	9.75534e-162
CP029480.1|AWV97976.1|1723558_1724338_-|short-chain-dehydrogenase	gnl|CDD|187602	cd05344, BKR_like_SDR_like, putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR. This subgroup resembles the SDR family, but does not have a perfect match to the NAD-binding motif or the catalytic tetrad characteristic of the SDRs. It includes the SDRs, Q9HYA2 from Pseudomonas aeruginosa PAO1 and APE0912 from Aeropyrum pernix K1. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	1.1581e-79
CP029480.1|AWV97995.1|1742788_1743634_+|hypothetical-protein	gnl|CDD|273146	TIGR00571, DNA_adenine_methylase, DNA adenine methylase (dam). All proteins in this family for which functions are known are DNA-adenine methyltransferases. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). The DNA adenine methylase (dam) of E. coli and related species is instrumental in distinguishing the newly synthesized strand during DNA replication for methylation-directed mismatch repair. This family includes several phage methylases and a number of different restriction enzyme chromosomal site-specific modification systems. [DNA metabolism, DNA replication, recombination, and repair].	1.1158e-104
CP029480.1|AWV97985.1|1730081_1731521_-|arylsulfatase	gnl|CDD|293750	cd16026, GALNS_like, galactosamine-6-sulfatase; also known as N-acetylgalactosamine-6-sulfatase (GALNS). Lysosomal galactosamine-6-sulfatase removes sulfate groups from a terminal N-acetylgalactosamine-6-sulfate (or galactose-6-sulfate) in mucopolysaccharides such as keratan sulfate and chondroitin-6-sulfate. Defects in GALNS lead to accumulation of substrates, resulting in the development of the lysosomal storage disease mucopolysaccharidosis IV A.	0
CP029480.1|AWV97981.1|1727047_1727662_+|FAA-hydrolase-family-protein	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	4.03672e-59
CP029480.1|AWV97989.1|1734773_1735628_+|xylose-isomerase	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	6.96908e-14
CP029480.1|AWV97983.1|1728258_1729167_-|DUF4357-domain-containing-protein	gnl|CDD|198394	cd10447, GIY-YIG_unchar_2, GIY-YIG domain of uncharacterized hypothetical protein found in bacteria and archaea. The family includes a group of uncharacterized hypothetical proteins, mainly found in bacteria and a few found in archaea, with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.	7.89656e-39
CP029480.1|AWV97990.1|1735679_1736282_-|SET-domain-containing-protein-lysine-N-methyltransferase	gnl|CDD|376403	pfam00856, SET, SET domain. SET domains are protein lysine methyltransferase enzymes. SET domains appear to be protein-protein interaction domains. It has been demonstrated that SET domains mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). A subset of SET domains have been called PR domains. These domains are divergent in sequence from other SET domains, but also appear to mediate protein-protein interaction. The SET domain consists of two regions known as SET-N and SET-C. SET-C forms an unusual and conserved knot-like structure of probably functional importance. Additionally to SET-N and SET-C, an insert region (SET-I) and flanking regions of high structural variability form part of the overall structure.	8.20429e-10
CP029480.1|AWV97993.1|1740178_1741138_-|galactose-oxidase	gnl|CDD|276965	sd00038, Kelch, Kelch repeat. Kelch repeats are 44 to 56 amino acids in length and form a four-stranded beta-sheet corresponding to a single blade of five to seven bladed beta propellers. The Kelch superfamily is a large evolutionary conserved protein family whose members are present throughout the cell and extracellularly, and have diverse activities. Kelch repeats are often in combination with other domains, like BTB and BACK or F-box domains.	7.04929e-32
CP029480.1|AWV97988.1|1733847_1734627_+|TIGR00266-family-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	1.63119e-83
CP029480.1|AWV97992.1|1739736_1740192_-|DUF4440-domain-containing-protein	gnl|CDD|379209	pfam13474, SnoaL_3, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	0.00249494
CP029480.1|AWV97982.1|1727777_1728074_-|addiction-module-antidote-protein,-HigA-family	gnl|CDD|274228	TIGR02607, Virulence-associated_protein_I, addiction module antidote protein, HigA family. Members of this family form a distinct clade within the larger family HTH_3 of helix-turn-helix proteins, described by pfam01381. Members of this clade are strictly bacterial and nearly always shorter than 110 amino acids. This family includes the characterized member HigA, without which the killer protein HigB cannot be cloned. The hig (host inhibition of growth) system is noted to be unusual in that killer protein is uncoded by the upstream member of the gene pair. [Regulatory functions, DNA interactions, Regulatory functions, Protein interactions, Mobile and extrachromosomal element functions, Other].	2.34148e-32
CP029480.1|AWV97991.1|1736425_1739359_-|helicase-SNF2	gnl|CDD|350770	cd18012, DEXQc_arch_SWI2_SNF2, DEAQ-box helicase domain of archaeal and bacterial SNF2-related proteins. Proteins belonging to SNF2 family of DNA dependent ATPases are important members of the chromatin remodeling complexes that are implicated in epigenetic control of gene expression. The Snf2 family comprises a large group of ATP-hydrolyzing proteins that are ubiquitous in eukaryotes, but also present in eubacteria and archaea. Archaeal SWI2 and SNF2 are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	6.44908e-107

Protein sequences

>CP029480.1|AWV97985.1|1730081_1731521_-|arylsulfatase
MKKLLFLLPIAFLLQATVSFKAPKTPNIVLIFMDDMGYGDLSCYGASTYRTPNIDRLAAEGIRFTNFLSAQAVCSASRAGLMTGTYPNRIGVSGAFFPNAGVGIADQETTMAEMLKQKGYATAIFGKWHLGHEKQFLPLQHGFDEYTGLAYSNDMWPIWYNGKHEKGTFKEHWPTLHLIEGNEETRPITTLEDQAELTTLYTEKATDFIKRNARKPFFLYVPHTMPHVPIDVSSKFKGKSGQGLYADLMMEIDWSVGEIMKELKTQGLDDNTLVIFTSDNGPWINYGNHAGSTGGLREGKGVSYEGGQRVPGIMRWKGQVPAGMVCNQLSSTIDIFPTLASITGASLPNHKIDGVNLSEILEGNMDAKPRDFFAYYYRKNNLEAVRKDHWKLVLPHTGRTYKGFLPGNDGYPGPNTEQHEEPLALYDLRRDAGEEYDVQRQHPEIVEELQAYAEKIRADLGDEITGVEGSGRRPLGKLR
>CP029480.1|AWV97984.1|1729229_1729934_-|short-chain-dehydrogenase
MKTALITGGSKGIGYGVAEKLINDGIKVAITARTEADLKEATAALNKIKEGFAIGIVSDVKDLASQEAAVKQVLDTWGQIDYFIANAGVGHFAPIQEMTAEQWQQTIDINLTGLFFSAKASLDALKATKGYFITISSLAGTNFFAQGAAYNASKFGAVGFSQAMMMDVRNDDIKVTTIMPGSVSTYFAGHTPSDADAWKIQPEDIGQIVSDLIKMPARTLPSKIEVRPSKTAKG
>CP029480.1|AWV97983.1|1728258_1729167_-|DUF4357-domain-containing-protein
MTLGKSIRIYLKEGSVTGIKLAEVVNLTIQALSSPRNKFTDLNEYFYKEVNTQGVYFLIGTDDETGKPKVYIGEAENVWERLKNHAINKDFWSEVILFTSKDDNITKSHIKYLESRLLEITKQTERYLLDNSNTPSLSSLPLPDRDAMEEFILNIKLLNGVLGHKFLEAQISYKETISVIQDETTMPNVSNNLLDETELILSTKNITATALQTDEGLVVLSGSYVSEKPSKNYGYKTLREELIKDGTIQKVKNGKLAFVKQHLFASPSAAAAVIVGYSINGRRSWKDQKGRTLSEIEKSQIK
>CP029480.1|AWV97982.1|1727777_1728074_-|addiction-module-antidote-protein,-HigA-family
MKTLNNIHPGEILKEEFLIPLEISAYRLSKETFIPQTRISEIIKGNRRITADSALRFSKFFGTSAKFWLGLQDDFDLEEEESCKAQELDSIKTIEYAS
>CP029480.1|AWV97981.1|1727047_1727662_+|FAA-hydrolase-family-protein
MKILAIGKNYVNEGEDKNAGKTGNQIIFSKPESSLATGNVDVEYPSFTQDLRYEAELVIKIGTKGKNISEADAAKHISEIGIGIDYTAKDIFDESRSGKGPWDLGKGFDGAAPMSTFKPVSAFPDLDNINFDLKINGEQKQVGNTSLMVYNFAEIIAFVSKFMTLEPGDLIFTGTPASGTGQIHKGDHLQASIEGELILDFKMV
>CP029480.1|AWV97980.1|1725701_1726880_-|sodium:proton-antiporter
MTTAILITFCSLLLIAYLFDITSARTKIPSVIMLLLLGWGMKEVTVFLGFSLVDFSTLLPVLATIGLILIVLEGSLELKLNSSKIGLLKKSVLGALIPMISLSFILAYAFHYFGDFPFKVSLINAIPLCVISSAIAIPSVINLDDGEKEFVVYESSFSDILGILFFNFIALNETIGLLSVVNFGLHMLIMLVVSVLGTIGLSLLLSRIDHHVKFVPIILLIVLVYAILKSYHLPALLFILLFGLAIGNLKQFEKINWFKKLKTDNLKKEIKRFEEITIEGAFLVRALFFIIFGYMIKTSEILNTDTIFWALGIVILVFFIRAVQLKVSRFDLRPLVYIAPRGLITILLFISIEPENTITLVNNSLIIQVIILTAIIMGMGLMAKPKPPKIEE
>CP029480.1|AWV97979.1|1725237_1725648_-|hypothetical-protein
MNPIFKNILAIVAGVIVGSAVNMGLVMLGPILIPPPEGADITTMKGLTEAMPLMQPKHFIFPFLAHALGTLAGAWVVAKIAATRKLQMAMTIGLFFLFGGIMNIQMLPGSPEWFNVLDVVLAYLPMAWLGRKLAKG
>CP029480.1|AWV97978.1|1724877_1725228_-|ribose-5-phosphate-isomerase
MPKVTYQVYVIELNKKVFTLNSKFREANPQFNGVLECLYVGMTSKTPKERFLQHKTGYRNKKGYKLSANIVQKYGMYLRPSLYNHIEPVNTRAEALKLEERLALDLRRQRYAVWHN
>CP029480.1|AWV97977.1|1724519_1724816_-|hypothetical-protein
MYKDLITYELAENISEEQLLKVAGQIVNDWMKKQPGFISWEINLNSNGSYTDIVTWESKETAKASEKDMVNIPNAGDWFACYKKGSISSQNLTSLVIF
>CP029480.1|AWV97976.1|1723558_1724338_-|short-chain-dehydrogenase
MNLNLKNKYALVCGGTDGIGWASAVELAKMGANVWLFARNKEKLKQKVALLDISKGQRHRFLVADFTDRKSVEAALATNKCQFHVLVNNTGGPAGGAILEEAPEKFQETFEQHLVMNQIITQAVVPFMKAEKFGRIINIISISVKQPILGLGVSNTIRWAVAAWAKTLSKELSHTGITVNNVLPGYTKTGRLEQVNKMRAKNENKSIEKLEQEMEANVPSGRFATPEEVAAAVAFLASPAAFSINGVNLPVDGGLAATL
>CP029480.1|AWV97986.1|1731961_1733461_+|glutamate--tRNA-ligase
MSVRVRFAPSPTGPLHIGGVRTALYNYLFAKKNGGELILRIEDTDQTRYVEGAEEYIVDSLAWLGINFDEGPKEGPNAPYRQSERKELYHKHAQLLIDSGKAYYAFDTSDELAALRKELEEAKVDNPSYNSVTRMKMKNSITLGPDATKELIENGTPYVIRLKVPLKEEIRFQDAIRDWVVVHSSTIDDKVLLKADGMPTYHLANIVDDHEMAITHVIRGEEWLPSAPLHILLYKAFGWEHPKFAHLPLLLKPEGPGKLSKRDGDIGDFPVFPTEWNDGKGEVMRGFREDGYLPEAVLNFLALLGWNPGTEQEIFTLEGLVEAFSLDRINKSGARFDVAKAKWFNQHYIKEMDDAALVALVNEQVKDEALAANLVKLNKDRVTFVAEIVTLVPYLFEAPSAYDEQVAGKAWNDLAKQGMPVIIDLVNGMAAADFHSEAIHNTLWEGLAAKEIKPGKVMQALRLALTGEGKGPDLMLMLEILGQKQVVERIQTALEKLGA
>CP029480.1|AWV97987.1|1733653_1733851_+|hypothetical-protein
MGKKKELNDDKPKVHKDLDGFDIKINTFGEIQMSYDVEKINNFLNDNVDDKKLKDVDPPKTKKKK
>CP029480.1|AWV97988.1|1733847_1734627_+|TIGR00266-family-protein
MRSHEIDYEILGEDIQVVQIELDPSETVIAEAGSMLFMEDGIQFETKMGDGSNANESILGKLFKAGSRVLMGESLFMTHFTNRGHGKRKVAFAAPYPGTIKAVDLSQINGNTLIVQKDAFLCAAMGTQISIHFNKRFGAGLFGGEGFILERIQGDGLAFIHSGGVVMERTLNNETLRIDTGCIVGYEPQLNFDIQSAGGLKSMVFGGEGMFLATLSGTGKVWIQSLPISKLIRRLSPAGGNANKESGSVLGGITDMFER
>CP029480.1|AWV97989.1|1734773_1735628_+|xylose-isomerase
MKRRDFISQGSAALGLAMMSGNLLANGNAGTVKKFGCQLYSVRDLMPKDAKGTMEKLAGMGYKLFESYSADPFWGMNPKECKTFLKDIGVKMISTHMLLDGITDELAANAAEVGLKYIMCPFIGMQPNMDAWKKVADKFNAAGDICNRHGLKFGYHNHSYSFAFVSGMKGQMVLLKNTDPDKVCFELDMCWSEAAGENTMAHLKEYGDRYELCHIKQLISIEPKEGEQRPVQTDLSDGVIDYTKLLRVAKDNGMKYYLVEQEQYPKDSITSMANDAEFMKNLVF
>CP029480.1|AWV97990.1|1735679_1736282_-|SET-domain-containing-protein-lysine-N-methyltransferase
MIHPHTKLVFLNEQMGYGVFATRFIPKGTITYVKDSLEISISDIDFQRHSPELQEVIEKYSYRDQHGDKIISWDFGKYVNHCCNCNTISTGYGFEIAIRDIYPDEEITDEYGIFNLTEEMELSCGETCCRKKITPEDFSMHYQSWDEKIKQSIFHLFDVNQPLLSFIDDATKNDLETLQQDPNQYKSVSALMYQNTKVAA
>CP029480.1|AWV97991.1|1736425_1739359_-|helicase-SNF2
MKVSTSEPFNIIYSLYQHQYLGYLFESFMVQLNHRGELTFAHQNVSSKNIEEFSKGIDDVDIELVNLMDAIHQDTILQKFNPKKLKPFDYFTKVYAGERPDLGMQAAIEEYLNNYRAAILPKLVGKRFFIMGEDGDPTRQEVKVMGEKTKVFMNFQRKEDHTIYFPVLKCLGEKVRLQHVGAQMLSDSPAFLLSENRLHYFDKHIDGKKLRPFFDKNNIRIERRIEKTYFRKFVGPLIAQFNVFGHGEGFEITEERATASPELLITDLSTKKQSPTLFDTPAKAADSPDKINFDLSFVYGNSTFRFDSLAANANVKVEEKGDGWVFHKIKRDLDFEKEIITKIKALGQDLIHGRKALNKNEGFSWLQLNAKALEEAGIAVKQSADSEKRYHLGTSSIEVSIEENSDWFDIKTKVQFGSFEVPFLKLRELVLANIREFKLPNGHIAVIPEEWFIRYHELFTLTDIGEDDELILKKHHLNLVQNLEENGLATTVIGRKLQGLNNFEEIKSYEVPSNFQGELRPYQKAGYDWINFLRDFNLGGCLADDMGLGKTVMTLAFLQTLKNDGVKNPTLLIMPTSLIYNWEKEAERFTPELKILKHTGGQRIKKTDHFKDYDLILTSYGVLRLDVKFIEKFRFEYVILDESQAIKNPSSNISKSVRLLNCRNRLILTGTPLENSTMDLWSQMTFINPGLLGSQAYFKDKYQLPIEKKRDEAASKRLYSKIKPFMLRRHKSQVATELPEKIESVQYCDMSEEQEKVYEETKAYYRNMIIDHIQEKGVNKSQLVVLQGLSKLRQMANNPLMIDPDYEGESGKDSDVIHKLKSIIESGSKVLIFSQFVKHLTIIRKYLIDNKISHSYLDGSTKNREKEVDNFQNDDSIKVFLISLKAGGVGLNLTAAEYVFLLDPWWNPAIEAQAVDRAHRIGQKNTVFTYKFISRNTIEEKILALQNKKKRLFDELITTEETFMKSLSQDDILNLLE
>CP029480.1|AWV97992.1|1739736_1740192_-|DUF4440-domain-containing-protein
MAANKIAFLLLIFIAPLTLKAQKKSNQEQLKSLIQNSFDDIFSEQKKEKVTQYYTDDFLLLEAGVVWNMDSVYSYIERANARKIKPERINTFDFLEIKVKGKTAWVAYQNYADIRIDGKSVVKLHWLESGSAIKTKEGWKLELLHSTVVPR
>CP029480.1|AWV97993.1|1740178_1741138_-|galactose-oxidase
MKKILILLALSVSLSGFSQEWATLETIGESTPRGENSMVAIGKKLYLFGGRGMKPMEVYDTRTNTWEKKGEIPLEIHHFQAVAYDGEIYVLGALTGPFPHETPIPNIYIYNPEKDEWRKGDEIPRKRGSAACFVYNDKIYVVNGIIDGHWDGHVAWFDEYDPKTGAWRELPDSPNARDHVAAGVVKNKVVIAAGRKSRHRTGEVMTLTVPFTDIYDFKTNTWTTVEGSNIPTLRAGPGVATLGSKVLFMGGEAADQKLAHNEVEAFDLKTMKWTTLPHMIRGRHAIGAAKVGKKIYISSGVGNSGGSPELNSLECYGCK
>CP029480.1|AWV97994.1|1741163_1742576_-|hypothetical-protein
MLRICSFLLCLAALASCSKKSGLKTGSENIKQYTDTRAIYDRYCSSCHGEKVEAFVDRKWQHGKTKDAIIASISNGYIDAGMPIWKNTIQPEDISKLADLIVTSLSTVDQYNFEDVEKTDTYKSKGITVKLETVIDGLDSPWGITTLPDGSLLVTDRAGDLWKIAPDKSKSKITGVPEVLATGQGGLFDIKLHPNYEENGWIYLTYAKHKNENGRVVSTTAMTRGKLQGNTLVSKEDIFEAVPYSSTRHHYGARMIFDNDGYLFVSVGDRGNRDKNPQSLDNSCGKIHRIKDDGSIPEDNPFYNTPDAIKSIWSYGHRNPQGLDIDRATNTIWEHEHGPRGGDELNIIQKGKNYGWPVISYGINYDATTFTDITEKEDMLQPELYWIPSIAPCGMTYVTSDKYGAWQGDILAGSLRFKYLNKVALKDGVVGNEEKLLPNIGRLRSVTQGADGFIYVGVENPGVVYKLMPQ
>CP029480.1|AWV97995.1|1742788_1743634_+|hypothetical-protein
MGKNKLIGPFLKWVGGKRQLMPAITKLMPTEYSTYYEPFIGGGAVLFHHQPSLAVINDFNKELINVYEVIKNRPEELIQDLKTHKNESAYFYQLRLLDRQEGFEKMSEIKKASRVIYLNKTCFNGLYRVNSAGEFNSPFGRYKNPNIVNEITIRAVSKYLNDNKISILNKDFEEAVKGAKKGDFVYFDPPYDPVSKSSSFTGYVQGGFGDEEQIRLRDLCVSLDNKGVDFLLSNSATPFIKDLYKDFNVKIVKATRQINSNASKRGEVNEVLIRNYGSNQK

Crispr_ID: CP029480_3

• CRISPR_ID: CP029480_3
• CRISPR_location: 3071347-3071483
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of CP029480_3

Consensus_repeat	Method
GACGCGTAGTCCGTCTACCTACTCGGGCGATACGAACTATT	CRISPRCasFinder

spacers of CP029480_3

>3.1|3071388|55|CP029480|CRISPRCasFinder
TAGGCATAAAAAAACCCCAACACTTACGTATTGAGGTTTAATAAAAAAGTGACGA

CRISPR arrays and Neighbor proteins around CP029480_3

CRISPR arrays

The CRISPR arrays of CP029480_3

>merge|CP029480|3|3071347-3071483|CRISPRCasFinder
GACGCGTAGTCCGTCTACCTACTCGGGCGATACGAACTATTTAGGCATAAAAAAACCCCAACACTTACGTATTGAGGTTTAATAAAAAAGTGACGAGACGCGTAGTCCGTCTACCTACTCGGGCGATACCAACTATT

>CP029480|3|3|3071347-3071483|CRISPRCasFinder
GACGCGTAGTCCGTCTACCTACTCGGGCGATACGAACTATT	TAGGCATAAAAAAACCCCAACACTTACGTATTGAGGTTTAATAAAAAAGTGACGA
GACGCGTAGTCCGTCTACCTACTCGGGCGATACCAACTATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP029480.1|AWV98964.1|3083164_3083710_-|DinB-family-protein	unknown	unknown	gnl|CDD|378981
CP029480.1|AWV98966.1|3085381_3086053_+|DUF4290-domain-containing-protein	unknown	unknown	gnl|CDD|379482
CP029480.1|AWV98953.1|3064063_3064480_+|DUF1761-domain-containing-protein	unknown	unknown	gnl|CDD|369962
CP029480.1|AWV98958.1|3078408_3079095_-|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|223816
CP029480.1|AWV98954.1|3064480_3065062_+|hypothetical-protein	unknown	unknown	gnl|CDD|226851
CP029480.1|AWV98949.1|3057128_3059546_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
CP029480.1|AWV98952.1|3063298_3063988_+|DNA-binding-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
CP029480.1|AWV98955.1|3065058_3065634_-|NAD(P)H-dehydrogenase	unknown	unknown	gnl|CDD|225158
CP029480.1|AWV98950.1|3059617_3060658_+|hypothetical-protein	unknown	unknown	gnl|CDD|225117
CP029480.1|AWV98960.1|3080495_3081137_+|oxidoreductase	unknown	unknown	gnl|CDD|187560
CP029480.1|AWV98959.1|3079091_3080348_-|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|223715
CP029480.1|AWV98967.1|3086075_3087380_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl|CDD|236486
CP029480.1|AWV98965.1|3083684_3085235_-|glycoside-hydrolase	unknown	unknown	gnl|CDD|224563
CP029480.1|AWV98948.1|3055755_3057114_-|hypothetical-protein	unknown	unknown	unknown
CP029480.1|AWV98956.1|3065709_3066492_-|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225117
CP029480.1|AWV98963.1|3082247_3083159_+|DUF58-domain-containing-protein	unknown	unknown	gnl|CDD|224635
CP029480.1|AWV98951.1|3060806_3063089_-|beta-N-acetylhexosaminidase	unknown	unknown	gnl|CDD|119333
CP029480.1|AWV98957.1|3066771_3070461_+|phosphoribosylformylglycinamidine-synthase	unknown	unknown	gnl|CDD|235394
CP029480.1|AWV98962.1|3081767_3082235_+|hypothetical-protein	unknown	unknown	gnl|CDD|223868
CP029480.1|AWV98961.1|3081137_3081533_-|DNA-binding-protein	unknown	unknown	gnl|CDD|378691

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP029480.1|AWV98952.1|3063298_3063988_+|DNA-binding-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	5.6e-53	175.1	0.6

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP029480.1|AWV98964.1|3083164_3083710_-|DinB-family-protein	gnl|CDD|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	1.59961e-06
CP029480.1|AWV98966.1|3085381_3086053_+|DUF4290-domain-containing-protein	gnl|CDD|379482	pfam14123, DUF4290, Domain of unknown function (DUF4290). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 200 and 221 amino acids in length. There are two conserved sequence motifs: EYGR and KLWD.	1.74765e-68
CP029480.1|AWV98953.1|3064063_3064480_+|DUF1761-domain-containing-protein	gnl|CDD|369962	pfam08570, DUF1761, Protein of unknown function (DUF1761). Family of conserved fungal and bacterial membrane proteins with unknown function.	4.4079e-15
CP029480.1|AWV98958.1|3078408_3079095_-|DNA-binding-response-regulator	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.02631e-62
CP029480.1|AWV98954.1|3064480_3065062_+|hypothetical-protein	gnl|CDD|226851	COG4430, COG4430, Uncharacterized protein conserved in bacteria [Function unknown].	2.50471e-33
CP029480.1|AWV98949.1|3057128_3059546_-|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	1.41735e-37
CP029480.1|AWV98952.1|3063298_3063988_+|DNA-binding-transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	2.21395e-50
CP029480.1|AWV98955.1|3065058_3065634_-|NAD(P)H-dehydrogenase	gnl|CDD|225158	COG2249, MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only].	2.5725e-55
CP029480.1|AWV98950.1|3059617_3060658_+|hypothetical-protein	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.85419e-24
CP029480.1|AWV98960.1|3080495_3081137_+|oxidoreductase	gnl|CDD|187560	cd05250, CC3_like_SDR_a, CC3(TIP30)-like, atypical (a) SDRs. Atypical SDRs in this subgroup include CC3 (also known as TIP30) which is implicated in tumor suppression. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine rich NAD(P)-binding motif that resembles the extended SDRs, and have an active site triad of the SDRs (YXXXK and upstream Ser), although the upstream Asn of the usual SDR active site is substituted with Asp. For CC3, the Tyr of the triad is displaced compared to the usual SDRs and the protein is monomeric, both these observations suggest that the usual SDR catalytic activity is not present. NADP appears to serve an important role as a ligand, and may be important in the interaction with other macromolecules. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.05242e-82
CP029480.1|AWV98967.1|3086075_3087380_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl|CDD|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
CP029480.1|AWV98965.1|3083684_3085235_-|glycoside-hydrolase	gnl|CDD|224563	COG1649, COG1649, Uncharacterized protein conserved in bacteria [Function unknown].	3.94653e-69
CP029480.1|AWV98959.1|3079091_3080348_-|two-component-sensor-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.18079e-41
CP029480.1|AWV98956.1|3065709_3066492_-|AraC-family-transcriptional-regulator	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.60289e-10
CP029480.1|AWV98963.1|3082247_3083159_+|DUF58-domain-containing-protein	gnl|CDD|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	1.95267e-23
CP029480.1|AWV98951.1|3060806_3063089_-|beta-N-acetylhexosaminidase	gnl|CDD|119333	cd06563, GH20_chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. This GH20 domain family includes an N-acetylglucosamidase (GlcNAcase A) from Pseudoalteromonas piscicida and an N-acetylhexosaminidase (SpHex) from Streptomyces plicatus. SpHex lacks the C-terminal PKD (polycystic kidney disease I)-like domain found in the chitobiases. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	0
CP029480.1|AWV98957.1|3066771_3070461_+|phosphoribosylformylglycinamidine-synthase	gnl|CDD|235394	PRK05297, PRK05297, phosphoribosylformylglycinamidine synthase; Provisional.	0
CP029480.1|AWV98962.1|3081767_3082235_+|hypothetical-protein	gnl|CDD|223868	COG0797, RlpA, Lipoproteins [Cell envelope biogenesis, outer membrane].	2.80502e-42
CP029480.1|AWV98961.1|3081137_3081533_-|DNA-binding-protein	gnl|CDD|378691	pfam11680, DUF3276, Protein of unknown function (DUF3276). This bacterial family of proteins has no known function.	9.48484e-32

Protein sequences

>CP029480.1|AWV98957.1|3066771_3070461_+|phosphoribosylformylglycinamidine-synthase
MIHFFGGQANTVFAVQTESTISDEDIKKLIWLFQSQIDHKHTKTNDSKAILTASFVGPRAAMITPWSTNAVEITQNMGISGLIRIEEFKEVEGDEVSFDPMLSQKYNSLTQDIYTINIKPEPIIEIEDINAYNLSEGLSLNEEEVNYLVELSKKLERKLTDSEVFGFSQVNSEHCRHKIFNGTFIIDGEEKPTSLFKLIKKTSQENPNDIVSAYKDNVAFVKGPTVTQFAPKSADKPDFYQEKDFDSVISLKAETHNFPTTVEPFNGAATGAGGEIRDRLAGGQGSLPLAGTAVYMTSYSRLEENRPWENAMDERPWLYQTPMDILIKASNGASDFGNKFGQPLISGSLLTFEHIENSRKLGFDKVIMMAGGIGYGKASQAIKAVPEKGDKVVILGGENYRIGMGGAAVSSADTGEMASGIELNAVQRSNPEMQKRAANAIRGLVESEHNPIVSIHDHGAGGHLNCLSELVEETGGVIDLDRLPVGDPTLSAKEIIGNESQERMGLVIGEKDIDTLKKIADRERSPMYTVGEVTGEHRFTFVSKTTGAKPMDFAISDMFGSSPKTIMDDKTVVRNYADLSYSKEKIGEYLNKLLQLEAVASKDWLTNKVDRCVGGKVAKQQCAGPLQLPLNNVGVMALDFKGKEGIATSIGHSPVSALVNPDAGSRNSIGEALSNIVWAPLPEGLKSVALSANWMWACKNEGEDANLYKAVEACSEFAIALGINIPTGKDSLSMKQKYPNDEVIAPGTVIISAGSACSDIKKVVEPVLKRDGGNIYYLNLSKDSFKLGGSSFAQILNKIGKEVPSVTDAAYFKTAFNTLQDLIKEGKITAGHDIGSGGLITTLLEMCFANVNLAADYDLTGLGEADFVKTLFNENIAVVFQAESEVEAVFKTNGIDIIKIGKPKEGNEVLIKSNDDQISLNVSDLRDTWFKTSFLLDQKQAFNGTAAERYKNYKNQALNYTFPSNFDGSAPIIDIKAVRPKAAIIREKGSNSEREMANAMFLAGFDVKDVHMTDLISGRETLEDIQFIGAVGGFSNSDVLGSAKGWAGAFLYNEKANTALKNFFKREDTLSVGICNGCQLLMELEMINPDHEIHGKLIHNDSHKHESIFTSVTVQKNNSVMLSTLEGTTLGVWVSHGEGKFNLPYGEEKYNIVGKYGYESYPANPNGSDFNTAMMCDSTGRHLVMMPHIERSTFPWNWAHYPANRQGDKVSPWLEGFVNARKWVEAKNK
>CP029480.1|AWV98956.1|3065709_3066492_-|AraC-family-transcriptional-regulator
MALIEERVNIPEEFNGVFSHFYMAHNKTDESIARTLMPSFQMLMIFSFGGSIKLNTSGANVIEITDCMVLGPLKKSIEYTLSPKAEMFVVNFVDDAFYLFFGPLMFLEGNPVDPEKLVDDNCFENLHGLLKNRNSKERTEVILSFCQPYLKENDNVFKEYKSEEIENPIKAVAQKTNKSERAIQTRYKQYYGFTSKEKIRFERFSKAIEIIQTGAFESWFDVILTCGFYDQSQLIHDFKHFIKLTPSQYLKFQQDICQVD
>CP029480.1|AWV98955.1|3065058_3065634_-|NAD(P)H-dehydrogenase
MKYLIIYAHPLESSLNNYLKAVVEQKLSNHMHEVVVRDLNQLNFNPVLSDDDMVGQMKGIVSEDVKTEQEYITWADGIIMIYPIWWTGMPAIMKGYIDRVFSYGFAYRYDKGVQKGLLVGKSLYVFNTHGKSKEEYQEIGMDVALKLTSDTGIFTYSGLEIKKHFYFGQADRVEASVVEKWVLEITESFSA
>CP029480.1|AWV98954.1|3064480_3065062_+|hypothetical-protein
MTHKKDDTFYPKSQTEWRAWLEENHVSQPSVWLIFYKKSSPKPSILWSDAVDEALCFGWIDSKKQTIDKDSYRQFFSRRKPNSTWSKINKEKVKTFIANGQMTPAGLKSIAIAKENGSWSILDSVEALIVPDNLEHEFSKHAGAKEYYQSLNKSHKKQVLYWIVAAKREETRMKRISEIAHLAGQNKRPKHII
>CP029480.1|AWV98953.1|3064063_3064480_+|DUF1761-domain-containing-protein
MFSNLSEINWLAVLVAFVPYFMLGGLWFTALFKKPYAISLGKENSLPEKPAPIFIMGPALCVLVITIATAILISALQISDSSSAIRLALLVGLGYLVANTMNIAINPNIPKPILYGVISGAYHLVGIIVTCLILVAMQ
>CP029480.1|AWV98952.1|3063298_3063988_+|DNA-binding-transcriptional-regulator
MEQNDTKRISRLTAILTQLQSKRILTAPELASKFGLSVRTIYRDIRALERAGVPIITEDGKGYSLMDGYKIPPVMFTESEANALILAEQLVLKNKDASLVKEYAEAINKIKAVLRNEVKDKANLLSDRTRNSLNLNTERTSSSLTTLQFALTNYFLVSINYTNESGEVSERLIEPFAILSTENWLLIAYCRKREAFRFFRLDRITHLEMQLEHFSPHKMTLQEYFDKYH
>CP029480.1|AWV98951.1|3060806_3063089_-|beta-N-acetylhexosaminidase
MNKFLTLTFIFLSSLSFAQDIIPKPVSYTAGDGRFVFDEHTSVSVNSLDKGLMEIIANLQEAVKACSGFGVPVQKKNENSITFLHDNKLKDEAYEITVSTSKVILKAGSNKGFFYAYQSLLQLLSDEIYDRNSALVKLSLPVCNIKDEPRFVYRGLMLDVGRHMMPVSFVKKFIDLMAMYKFNQFHWHLTEDQGWRIEIKKYPKLTEIGAYRKESPLGHDSENRGDGKPYGGFYTQEEVKEVVAYATSKYINVIPEIEMPGHAVAALASYPELGCSGGPYEVRTRWGVAKDVYCPTEKTFAFLEDVLTEVMTLFPSKYIHIGGDECPKDSWKASEFCQDLIRKEGLKDEHELQSYFISRIDSFLTSKGRKLIGWDEILEGGLSPNATVMSWRGTEGGIEAAKQKHDVIMSPNSFHYLDYYQGDPISEPLAIGGFLPLEKVYSYEPLAEPLAPEELKHILGVQANLWTEYISTPEKVEYMLFPRALAVAETAWSTAENKEYSDFENRVKRHFGKLAKLKVNYAESIYNIKAALKTTNKGEVLVNLNNIETAPNILYTLDGSEPNRRSNKYDGKTGILVKKQTTVKASLFNENGQKYGNTFEADIRVNKATGKFYEYRSKKTKYTGNTEMALTDGQIGNEKNLQTWVGLEGGKLDLTIDLTAVNELSNLSIGFLHSPGSWVMFPSSLEVSVSKKGKKFKTLSSQSFNKGGELSQFVERIKVNLNGKKARYIKVTAGSFGELPEGHAGAGADAWLFVDEIEVN
>CP029480.1|AWV98950.1|3059617_3060658_+|hypothetical-protein
MVGVIPRKELLSTQKEVMRIEEEDGRRIMYREICVEELLENSYVGDCIRFNTVEVSKKDNAAHISGVDFTTNKLPFKPNTAISISSDEPLIKIHFSLEGTYSYQPLTHIKYLVQIPENHCNMFYYPATEGRELYNEENTKAFELYIKPSVLKELLGTGYKRSLEKLDEAIKNSNTYLHWDKSTFIPPHIRNRILEVLQCPYKGEVRKRYIESSLTILFIEFLLGRESIAVTKDRAKLPNADYLALVKVETYIRKNLQKQLRIIDLAELAGFNATKLKRDFKKVYGLTIFKHITSLRMERAIKLITEEGVPIAQASYEVGFSHPQHFTTAFKRTMGYLPSQLKPTEL
>CP029480.1|AWV98949.1|3057128_3059546_-|TonB-dependent-receptor
MKGLFTAIFLLIFWNAQGLEVTGTISGTIYDASGKPMPYATVLIKKLNIGISSDDNGVYSIDKVPFGEHTVLVNFIGYNTVTKTIKLNNKNFETKVNFVLEEKTESLNEINVIGKTEETEKETQGFAVNVIKTKEASLRNIQTNELLNTTVGVKIRQNGGLGSEVSYSLNGLSGNSVRIFIDGIPISIYGSSFNLNSIPPSMIKNIEVYKGVVPGHLADDALGGAINIVLHKSAQSNFNASASYGSFNTFQTSVNGLYRYEESGFTVKASAFHNYSDNDYKVSGRSVVVTGLGGVQTPVTARRFNDAYRSTGGMAQIGFTDVKWADQFLIGLTGSDDYKEVQHGAFMTIIPYKGRFLESEALLSTLTYQKRDFLIDGLDVNVNGTYGKRNRIVNDTVAAAYSWNGQRAIDFRGNEYNYSWGSQQEGGPTLTKIDRNVASIRTGLSYAINKHHKFLVNHVYSGVDREDSDALRSVLENTFKGTRDLNKNIYSLTYELSALDDRLKASLFGKYYQQETISIDPTIEKGVDGKSKIVDETVSSNKKHDGYGFALSYALNSKITLLTSAEKAVRLPSETEVFGDDGDNVIANSSINPEQSRNYNVGFRLGTFAIRKHNFVVSTNLFARNIKDRIGLPIETSLNVDDELILYVNQGSATSKGIDAQLNYSYNKNFGLNFNVSRFDLKVINRGIEIDVPNTPFFTMNGSLRYSFKDLIQKNSRLNLFYTMYFTDDFSYITSQGTNTVGNDYFNVPQQLAQDFGLSYAFPKNRVVASFDIKNIFDKPVYDNLSVQKPGRAFYLKLNYSINKF
>CP029480.1|AWV98948.1|3055755_3057114_-|hypothetical-protein
MIKTILNNKTLALLLTFGLLNACTTNDEPVVEPEPEPEESRWITVAAAKMGENPGDGNGGTLIYSISSEDAKNPNFSIDPFNNGFIAPSNRTARLQSSEDGKTIFNISYAGDTGGNYTKYTVEGGQTFTPTGSPVSIAPYVGSAPRWIKLFDGDQTGAAVYVSNEHEINDNGTPDDASDDTYVRTDAKIGVVTLDLVNSAIKEFQEHSVPLTAQEEANGYYISRIDMPTLNAAGNKLYIGARLSKVDPATAESDGNGEILGSKTIILDYPSLLNPTVITSTVGHGNTNGYRSINAFEYNGSVYQANQSDPEGSHILKINANNEYDNSYDFNLDDALGIEGAYVLAWRPAANGKAVVAYRHNGSADGVAGAQGFFALVDLNTKTAQKIDAIPYDPDFYLFQYQGFVVDGNEIYLTQAAVGQNGNIYVVNTESGEVTKGAQLVNIAGSHFIGVF
>CP029480.1|AWV98958.1|3078408_3079095_-|DNA-binding-response-regulator
MMAKILYVEDDKNLSYVIKDNLEEEGFEISHFADGKEALKNFQKEKFDLCLLDVMLPELDGFSLAEKIREQNEQIPIIFLTAKVLQEDKIEGLKIGGDDYITKPFSIEELTLRIKVFLKRSTVSDIEDEQNEYRIGKYNFSFSQLILDSEEGIKKLTHREAEVLKYLCDKRDSVIKREDILTKIWGRDDYFLGRSLDVFITRLRKMLATDDSLKIENVHGVGFRFVTE
>CP029480.1|AWV98959.1|3079091_3080348_-|two-component-sensor-histidine-kinase
MTRNAIRLIIITGSLAIAAIIGIQIFWVKRAYDIENDRFRQSAVEALNEVANNISRIYDLTEIETPVERLEDDYYVVNLRTPLDAAVLEHYLRQEFKRHDVNTSFEYGIYDCDTDEIRYGGSVNANFEIDHIEPTILPKTDKFLNYFGVRFPSKGSFLFQNLDFWILSSIVTLLITGFFVYAMFVILRQKKLSEVQRDFVNNMTHEFQTPISTIRVATDVLAQDKIMEQPERMKRYVQIIKQENLRLKNQVETVLTTAKVGKGKLELNIQLQELHVLLSEVLESVKLEIGSGLTLKLDAEQTSIYADKVHLLSVVRNLVENAIKYSKKPADITVVTKNDDYGVVLEVKDKGIGIPEEYLGKIFNKFYRVPTGNVHNVKGFGLGLNYVEQIVKAHKWKINVESKYGVGSIFRINIPQEK
>CP029480.1|AWV98960.1|3080495_3081137_+|oxidoreductase
MSTDQKSALLVGASGLIGKSLLKQLLESTDYEKVIILVRRKIDLEHPLLEQRVIDFDKLGSLTFKTDHVFCTLGTTIKTAGSKEAFKRVDEDYPFQIAENCFKNGATLFAIVSSMGSDKNSRFFYNQVKGQVEEKLENIGFPYLGIFRPSMLLGDRNEKRIGETIGQAFMKGLGFLIPKKYKAIHVDKVALAMLEYAKRPNKGLSIIESDKML
>CP029480.1|AWV98961.1|3081137_3081533_-|DNA-binding-protein
MQNEEREMIYSKRVRAGKRTYFFDVRATRANDYYLTVTESRRQQRDGDFFYEKSKMFIYKEDFNKFVDALQETVDHIKTELLPEFDFEQFDNKEDSEKAEAAAPIVKEVEKDSEITDIDSDSFGDSELKWE
>CP029480.1|AWV98962.1|3081767_3082235_+|hypothetical-protein
MLNNVKIISFIFILSLFSSGEPEIKNFAPFLGTEFKGKASFYGPKFHGKTTANGEKMDQNAFTCAHKNLPFGTMLEVRNPENGTQVVVRVNDRGPFIKGRVLDVSAGAAKALKMRDNGVIDIEATIVGQDGKVFIKSTSPFSRFLNSEVVEQVTD
>CP029480.1|AWV98963.1|3082247_3083159_+|DUF58-domain-containing-protein
MMEKLDLGKVREYGNLELLARQMVEGFITGLHKSPFHGFSVEFAEHRLYNVGESTKHIDWKVFGKTDRLFVKRYEEETNLRCHLLIDTSSSMYYPAKNNGKLTFSCLAAATLANLMKKQRDAVSLTAFSDKIEVQTAVKSTGGHIHQIYVELEKLMTLSQPNKTSSVADTLHQIADSIHKRSLVVIFSDMFENMDDLTAIFSALQHLKHNKHEVLLFHVTEHSTERDFDFDERPYEFIDVETGEKVRAQPSQVKEQYQTAVQSFYKDLRLKCGQYKIDFVEADINQGFDQVMASFLTRRAKMK
>CP029480.1|AWV98964.1|3083164_3083710_-|DinB-family-protein
MNLFLLDINYTMENTLIESLKPYIDSLDSYSEEQFSFKQSPDIWSLAQMYEHIQASGFVFFLANINRCLEQRKGQLGGTPSEAGYVILKNNGFPLNQKFKRPDTDVNPIIVGNSLSYYKEGFSKLKEALLSTIPAIEKDAGEYRTNHFYFGMLNAKEWFLNTEFHFRHHLTQKAELESYLK
>CP029480.1|AWV98965.1|3083684_3085235_-|glycoside-hydrolase
MLKLLASATILIVLFYSCSKKPLESFQKEVEIPEFKAVNIKTSIPKSEFRGAWVATIANIDWPSQKGLNSETQKKEFQDIVKHHKKRGINALLVQVRAASDAFYAKSKEPWSEWLMGEQGKGPQPFYDPLEFMIEEAHQEGLEFHAWLNLNRGKHRLAGSVMPNHLIYTKPEWFISYGDYELYNFGLPEVRSYIIDVVMNIVREYDVDGIHFDDYFYPYKVTGLELEDHAAFAKYPNGFRSIEDWRRNNIDLVIKGISDAIKREKSWVSFGISPFGVWRNKSDDPLGSETRGGQPSYDLLFADTRKWAMEGWIDYIAPQIYFPFEHNLVPYGTLTDWWTKNHGKAKLYIGHGVYRVEANSSTKAWKDPNQIPRQLDYNRYSSGVDGSIFYNTNTFIKNNLGLADSIATRYKYPALVPEVNGVAKAIVQAPKRLLLTDIKEGLKLTWANETPKGFKNVVYRFKEGQELNAGDPEHILAITLSSEYVDKTRRSNTAYIYMITAVNRWNKESEPIFIRH
>CP029480.1|AWV98966.1|3085381_3086053_+|DUF4290-domain-containing-protein
MKEYGSNIQKLVEHVISVPDKDKRTKHAHILIELMRQIHPQMRDGNDYSKKLWDDLYIMANFDLDVDSPFPPPPKEILGKRPPKMPYRQANLKHKYYGRNIELLVLKAVATESYDERKAFVSYLVKLMQNSFLAWNKDNIQTETVLQQILDMSGYKLQDEVDAIRKDGLVPDANPKDGNRVPNRFNNAQTFRKNQSTGGNSNSGKRFKNNKNKGGKFKQRRRY
>CP029480.1|AWV98967.1|3086075_3087380_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MSSFKITGGKKLQGELTPQGAKNEALQILCAVILTREVVEIHNIPNIRDVNKLMELLEDMGVKRTKLGEGSYRFEASEVNFEYFETEAYKEKASSLRGSIMLLGPMLARFSKGKAPRPGGDKIGRRPLDTHFVGFQKLGATFTYEADDAFYTVDGENMEGGYVWMDEISVTGTANVVMAAVMTKGITTVYNAACEPYLQQLCKMLNRMGAKIEGVGSNLLTIEGVEEMSGCEHTMLPDMIEIGSFIGLAAMTKSEITIKNCQIKELGIIPATFKKLGIEMEFRGDDIYIPAQENYEINTLIDGSILTIYDAPWPGFTPDLISIILVTAIQAKGTLLVHQKMFESRLFFVDKLIDMGGQIILCDPHRATVVGLNRTHNLKGIRMTSPDIRAGVALLIAALSADGTSIIDNIEQIDRGYQNIDDRLNAIGAEIVRV

Crispr_ID: CP029480_4

• CRISPR_ID: CP029480_4
• CRISPR_location: 3854289-3854366
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP029480_4

Consensus_repeat	Method
ACCGATGTCATGTCCCTAAGGGAC	CRISPRCasFinder

spacers of CP029480_4

>4.1|3854313|30|CP029480|CRISPRCasFinder
ACCTTTTATTCAACAAAACAATCTTTTCCT

CRISPR arrays and Neighbor proteins around CP029480_4

CRISPR arrays

The CRISPR arrays of CP029480_4

>merge|CP029480|4|3854289-3854366|CRISPRCasFinder
ACCGATGTCATGTCCCTAAGGGACACCTTTTATTCAACAAAACAATCTTTTCCTACCGATGTCATGTCCCTACGGGAC

>CP029480|4|4|3854289-3854366|CRISPRCasFinder
ACCGATGTCATGTCCCTAAGGGAC	ACCTTTTATTCAACAAAACAATCTTTTCCT
ACCGATGTCATGTCCCTACGGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP029480.1|AWV99532.1|3861416_3862607_+|MFS-transporter	unknown	unknown	gnl|CDD|225371
CP029480.1|AWV99528.1|3856496_3858590_-|hypothetical-protein	unknown	unknown	gnl|CDD|223839
CP029480.1|AWV99516.1|3840986_3841385_+|hypothetical-protein	unknown	unknown	gnl|CDD|374446
CP029480.1|AWV99530.1|3859103_3860021_-|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase	unknown	unknown	gnl|CDD|234597
CP029480.1|AWV99531.1|3860117_3861341_+|alkyl-hydroperoxide-reductase	unknown	unknown	gnl|CDD|239264
CP029480.1|AWV99518.1|3843985_3844708_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|237084
CP029480.1|AWV99535.1|3864910_3865891_-|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl|CDD|274250
CP029480.1|AWV99521.1|3848626_3849664_-|hypothetical-protein	unknown	unknown	gnl|CDD|225814
CP029480.1|AWV99533.1|3862603_3863341_-|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl|CDD|236181
CP029480.1|AWV99517.1|3841442_3843791_-|hypothetical-protein	unknown	unknown	gnl|CDD|187676
CP029480.1|AWV99529.1|3858603_3858975_-|hypothetical-protein	unknown	unknown	unknown
CP029480.1|AWV99534.1|3863463_3864894_-|L-arabinose-isomerase	unknown	unknown	gnl|CDD|179503
CP029480.1|AWV99524.1|3852291_3852978_+|disulfide-bond-formation-protein-DsbA	unknown	unknown	gnl|CDD|239322
CP029480.1|AWV99519.1|3844836_3847812_+|hypothetical-protein	unknown	unknown	gnl|CDD|377403
CP029480.1|AWV99522.1|3849971_3850637_+|hypothetical-protein	unknown	unknown	gnl|CDD|225107
CP029480.1|AWV99523.1|3850949_3852152_+|aspartate-aminotransferase	unknown	unknown	gnl|CDD|235596
CP029480.1|AWV99526.1|3854500_3855268_-|hypothetical-protein	unknown	unknown	gnl|CDD|372685
CP029480.1|AWV99525.1|3853002_3854235_+|hypothetical-protein	unknown	unknown	gnl|CDD|224938
CP029480.1|AWV99527.1|3855273_3856506_-|peptidase-M14	unknown	unknown	gnl|CDD|349458
CP029480.1|AWV99520.1|3847821_3848544_-|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|225818

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP029480.1|AWV99532.1|3861416_3862607_+|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	6.69356e-55
CP029480.1|AWV99528.1|3856496_3858590_-|hypothetical-protein	gnl|CDD|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	1.64735e-103
CP029480.1|AWV99516.1|3840986_3841385_+|hypothetical-protein	gnl|CDD|374446	pfam16231, DUF4890, Domain of unknown function (DUF4890). This family consists of uncharacterized proteins around 200 residues in length and is mainly found in various Bacteroides species. The function of this family is unknown.	8.86488e-06
CP029480.1|AWV99530.1|3859103_3860021_-|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase	gnl|CDD|234597	PRK00050, PRK00050, 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH.	1.5373e-146
CP029480.1|AWV99531.1|3860117_3861341_+|alkyl-hydroperoxide-reductase	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	5.64841e-20
CP029480.1|AWV99518.1|3843985_3844708_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl|CDD|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	8.20525e-114
CP029480.1|AWV99535.1|3864910_3865891_-|GTP-3',8-cyclase-MoaA	gnl|CDD|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	7.24187e-125
CP029480.1|AWV99521.1|3848626_3849664_-|hypothetical-protein	gnl|CDD|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	3.61404e-30
CP029480.1|AWV99533.1|3862603_3863341_-|L-ribulose-5-phosphate-4-epimerase	gnl|CDD|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	8.68122e-156
CP029480.1|AWV99517.1|3841442_3843791_-|hypothetical-protein	gnl|CDD|187676	cd09618, CBM9_like_2, DOMON-like type 9 carbohydrate binding module. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. CBM9 domains found in this uncharacterized subfamily are typically found at the N-terminus of longer proteins that lack additional annotation with domain footprints.	8.64999e-51
CP029480.1|AWV99534.1|3863463_3864894_-|L-arabinose-isomerase	gnl|CDD|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
CP029480.1|AWV99524.1|3852291_3852978_+|disulfide-bond-formation-protein-DsbA	gnl|CDD|239322	cd03024, DsbA_FrnE, DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins.	6.89718e-74
CP029480.1|AWV99519.1|3844836_3847812_+|hypothetical-protein	gnl|CDD|377403	pfam04738, Lant_dehydr_N, Lantibiotic dehydratase, C-terminus. Lantibiotics are ribosomally synthesized antimicrobial agents derived from ribosomally synthesized peptides. They are produced by bacteria of the Firmicutes phylum, and include mutacin, subtilin, and nisin. Lantibiotic peptides contain thioether bridges termed lanthionines that are thought to be generated by dehydration of serine and threonine residues followed by addition of cysteine residues. This family constitutes the N-terminus of the enzyme proposed to catalyze the dehydration step, via glutamylation of the substrate during lantibiotic biosynthesis. The enzyme dehydrates Ser/Thr residues in the precursor by glutamylation.	2.67738e-111
CP029480.1|AWV99522.1|3849971_3850637_+|hypothetical-protein	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.21834e-29
CP029480.1|AWV99523.1|3850949_3852152_+|aspartate-aminotransferase	gnl|CDD|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	0
CP029480.1|AWV99526.1|3854500_3855268_-|hypothetical-protein	gnl|CDD|372685	pfam13715, CarbopepD_reg_2, CarboxypepD_reg-like domain. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.	0.000268336
CP029480.1|AWV99525.1|3853002_3854235_+|hypothetical-protein	gnl|CDD|224938	COG2027, DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane].	1.05086e-31
CP029480.1|AWV99527.1|3855273_3856506_-|peptidase-M14	gnl|CDD|349458	cd06239, M14-like, Peptidase M14-like domain; uncharacterized subgroup. Peptidase M14-like domain of a functionally uncharacterized subgroup of the M14 family of metallocarboxypeptidases (MCPs). The M14 family are zinc-binding carboxypeptidases (CPs) which hydrolyze single, C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. Two major subfamilies of the M14 family, defined based on sequence and structural homology, are the A/B and N/E subfamilies. Enzymes belonging to the A/B subfamily are normally synthesized as inactive precursors containing preceding signal peptide, followed by an N-terminal pro-region linked to the enzyme; these proenzymes are called procarboxypeptidases. The A/B enzymes can be further divided based on their substrate specificity; Carboxypeptidase A-like (CPA-like) enzymes favor hydrophobic residues while carboxypeptidase B-like (CPB-like) enzymes only cleave the basic residues lysine or arginine. The A forms have slightly different specificities, with Carboxypeptidase A1 (CPA1) preferring aliphatic and small aromatic residues, and CPA2 preferring the bulky aromatic side chains. Enzymes belonging to the N/E subfamily enzymes are not produced as inactive precursors and instead rely on their substrate specificity and subcellular compartmentalization to prevent inappropriate cleavage. They contain an extra C-terminal transthyretin-like domain, thought to be involved in folding or formation of oligomers. MCPs can also be classified based on their involvement in specific physiological processes; the pancreatic MCPs participate only in alimentary digestion and include carboxypeptidase A and B (A/B subfamily), while others, namely regulatory MCPs or the N/E subfamily, are involved in more selective reactions, mainly in non-digestive tissues and fluids, acting on blood coagulation/fibrinolysis, inflammation and local anaphylaxis, pro-hormone and neuropeptide processing, cellular response and others. Another MCP subfamily, is that of succinylglutamate desuccinylase /aspartoacylase, which hydrolyzes N-acetyl-L-aspartate (NAA), and deficiency in which is the established cause of Canavan disease. Another subfamily (referred to as subfamily C) includes an exceptional type of activity in the MCP family, that of dipeptidyl-peptidase activity of gamma-glutamyl-(L)-meso-diaminopimelate peptidase I which is involved in bacterial cell wall metabolism.	4.35462e-82
CP029480.1|AWV99520.1|3847821_3848544_-|DNA-binding-response-regulator	gnl|CDD|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	7.27647e-38

Protein sequences

>CP029480.1|AWV99525.1|3853002_3854235_+|hypothetical-protein
MKNTLVSLFLIAFLGACQVQKISNKVIHPSDDKHHLGYLFIDTITGDTLFQQNASRYFNPASTTKLFTWYSSLSLLGEKIPALKYYETADSLIFWGTGDPTFLRADFPENNTLVFLKSKANKKLIFSDANFQGKHYGQGWMWDDYLEAYQTEVSPLPIYGNLVTFNNQNIEPSYFEVLTQKSSDLKSKVLREEGQNHFSIAEKAKLKNVKIPFKTDGETLASLLSDTLNVPVIYDQNQVYDYAYATLFSEPRDSLIVPMLEHSDNMLAEQLMLMASGQISDSLSVTKAINYMLENKLSDLPQKPRWVDGSGLSRYNMFTPNDLVYLLQKIKGEIGIDKAFYILPKIGENHETYIWAKSGSMSGVYNLAGFIKTKKGKTLTFALMNNNFTKPVSTVRKEMAAFLEGIREAY
>CP029480.1|AWV99524.1|3852291_3852978_+|disulfide-bond-formation-protein-DsbA
MKKKINIDIVSDIACPWCFVGKRRLEEAIKSLDKYDLNINWHPFQLDPNIPQEGADKEEYMANKFGSVERYEMLAENLISAGDGVGISFDFKSAKTIPNTMKMHQLLHVASKEGFADSLKERLFKANFEEVLDLTQDATLVNIMKEFDWTEEYTLSVINDQEIAYWVTQEIRNYQQMGVTGVPFFIFNNKYAFSGAQPPQVFIDTIKDVSQKMEVAKAESCDIDDPNC
>CP029480.1|AWV99523.1|3850949_3852152_+|aspartate-aminotransferase
MSAAHQVSDRIQNLESSATIAMSQKSRELRDEGHDVINLSIGEPDFKTPEHICEEAKKAIDAGFHSYTPVPGIPELRKAIADKFKRDNNIDWAPANIVVSTGAKHSLANALQVMVNPGDEVVIFAPYWVSYSEMVKLAEGTPVIVKGSFENGFKVTPEQLEAAITDKTKVIMFSSPSNPTGAVFSKAELTAIAKVVEKHENVFVLADEIYEYINFMEEGHFSIGSIPAIKDRVITVNGMAKGFAMTGWRIGYIGAAEWIVKGITKLQGQVTSGTNHIAQRASVVAWDDMTSSETMKRAYLVRRKLVVDGLKSIPGFKVNTPDGAFYAFPDISDFFGKANGETKINNSDDFSMYLLLNAHVATVAGESFGAPDCIRISTAASDEALTEAIARIKKACSELK
>CP029480.1|AWV99522.1|3849971_3850637_+|hypothetical-protein
MQTLPKVLLIHRSTLICEVLRESLEQREYDVVSYATSGEDALKNTSKYKPDVIIVSNYLSDYSGLEIVNQLNKESFKGSFIFLSQSATDARLVHQKLNVAGHIHTFDGMSELFFALQEIRSGRQYTSQSVKKEISKSYKEETDSIQMDTAILKSLTPRELQIMQALADSNTTPQIAKQFLISPATVNNHRANIMHKLKLRGRNQLIGVAISLKPFYDSDAA
>CP029480.1|AWV99521.1|3848626_3849664_-|hypothetical-protein
MNAIIEQLRKNKAEIRLHILAWSIYYLVDFVFVIGFTEDVTQGMIVTYFCTVIVYTFCFYFIVEIYKKYFPNQKLKGVVFGILAVLLFSGLNFIWDIYVIEYEASVKRLEEKAWTLYLFETWRFSTSALYGFAYWIYLQRIDDQRLRREVEKQLHSAEIAFLRAQINPHFLFNTLNFVYGDVAEKSTEAGNAILSLTKLLRYSVESTKTENSSLRREVEAVTEYLVLQKLRFGGRAYVDFEKSGLFMLFVIPPLVLLSLVENAFKYGVIDDPETPIKINLDVDKNGLKFVCFNTKRLDFKDKETTSVGIKNIERRLELTYGSDYNLLVNEEDETYEVLLTIVWKK
>CP029480.1|AWV99520.1|3847821_3848544_-|DNA-binding-response-regulator
MILSVIVDDESAAIKVLENYVKRLSFVENVASFSNPVEALTFVNENQIDVVFLDINMPHLTGFSFMDMLKNDTKIVLTTAYSEYAIDGYKYDVVDYLTKPIPFDDFLRAVQRVQNRFLAASTANKLESLSDYIMVKTEHKGKYVKVKFENILYIESLKNYVAIYTLQKEQIITLLTMKELAEKLPKEHFIRTHKSFIVSLNHLKYVDGGEIVLQTDIDKIPLGITYRDTFFDLLESKMLQ
>CP029480.1|AWV99519.1|3844836_3847812_+|hypothetical-protein
MSKYTFLPELILRTPAKPFQSQLTELEIINLLKDKGFQETIFLASPSLYQAILDYNEGKLSEKSQKGVLSSAAKYIIRSHTRSTPFGLFAGTATLKWGEKTSISINQNYKRKTQLDFGVINDLYKKIKNNGQQLREVRLYPNSTFYIFQEEIRYIEKAVDGNEVSLQISALEKNDFILFVLNKAESGLTISELSGILEKEGIEKTEAHEFLISLIDSQILVDKLEPILNSTDKLESLISLHRNLGTEEDTVNELKKISSDLNQIDIEQESNIEKYLEFEDSINRKTFHTECFFELDEARASLNQNLQKNILEALTVLNTLKTRTEDNRLNHFKTKFERRFGSSEVPLLVALDTEKGLGYDKEFDIVIAPLIKELDWTPVKNLDETVKTESYLESLLKKALSQNCHEIKLEEENLPELNYDLNLSASSSILFKTISKNQILLEAVGGSSAINLICRFANSNPDLGHLVEKIAAKEVSNNPSVVFAEIIHLPNTKLGNVLSRKSVFEHEISFLGVGKGEKQIALRDLVVFLQEDTLFLKDLRSNQIIIPKLNCTHNVGETDLPVYKFLYDLQFQGLDGSLKFDWDGKINNNIFFPRVSYKGVIISLATWEFRKTALADVHKLKSINDFEKWHQKLNIPPLFVISEGDNDLLIDTKSEFLIQLFIDTVKNKKQLTLKEFLLNESQPVKNSYGESMANQFIATLLKSGEAYKLPGKEALKSVDTNQVLIKTENAPYSNWLYIKVYCPLASVDSILSNEIANALKEAFDKNLIDKWFFIRYRDPDFHLRVRFHLNDIEQYQELIKLLNHYISNQTDIWKVELGSYEPEYKRFAAIGIEAAESIFHFESSSYLNFLACTEADSREDIRWLYALKYIDDLMSFFEYSLSEKLNFISFVRNGFAEEFGLNQEKKKLIDKLYRENKQKINETLSQKSYIKPEVTLDLHCKKEDSFNKSTLAGLTHMCINRIMNTQPRLHEFVIYDFLLRSYKSILAQQKN
>CP029480.1|AWV99518.1|3843985_3844708_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MGRAFEFRKARKMKRWSSMAKTFTRIGKDIVMSVKEGGPDPSANSRLRAIIQNAKAANMPKTNVENAIKRASSKDQEDYKEVILEGYGLYGVAVLVECTTDNNKRTVANVRSYFSKTGGSLGTNGMLDFIFDRKCVFKIENKEGLDLEELELELIDFSVDDVFLDDETGEVNIYGEFASYGDIQKYLEENEFEVVSSGFERIPTDTKTLSEEQGADIDKLLEKLDEDDDVQNVYHNMVLE
>CP029480.1|AWV99517.1|3841442_3843791_-|hypothetical-protein
MIVYSLINTNYCCRILVLLQKPYQRDLRFFLIALLQFPLLAVSQSAIHDPSDYFLKVYRSAEKIDVDGEANERVWAKGEVAGEFWQLFPRAEDKSEIKTNIRAAFDDDFVYFLIEAFDSTNTYVSQSLKRDASIGLNDGVAIILDPINKKSNGFVFSCTPYNVQSEYQYGTDYAGITYAWDNKWYSAVKRLDDRYVVEMAIPFKTLRYNAGNTEWGINILRSDLKSNQLSSWTNIPVQFSALDLGYLGTLQFDGALGEQKSNISIIPYAIAGGHGDSENSTVEGWSGFIPGNGKNDNHSFHLNAGFDAKVAINASLNLDFTINPDFSQVEVDQQVTNLTRYSILYPERRTFFLENSDLFSNFGSTTFKPFFSRSLGLDENANAIPILYGARLSGNVAKKVRVGVMNMQTLKSGDFAAQNYTAASVHQRIGARSLIKGYFLNREATGLTGEELNDDLSLYGRNAGLEVNLIDRNGVNQFWAGYHKSIKKGIDKENDFYQLGYSYSGRTYSGFIEWADFSKDYYADMGFINRIETHAQMGASYTAPDTLIRAGFKHLYNHNTFTLRPKDSKVVQVVFGLSNFMAFFDNNKLSDKYHSLTGGVYFKNTSGINVEYKIQEDNLLYYFPLPTNKPLAPGNYKYSNVSFNYLGDERKNFVINGGVMFGKYYNADIRQYNLSMLIRKQPYYSMMLSAQFNDLLFPMDYGRTKLWLIGPKLEATLTNKLFWTTFLQFNTQENNFNINSRIQYRYSPMSDFFLVYSDNYYSNSFVNKNRAIVLKFNYWFSL
>CP029480.1|AWV99516.1|3840986_3841385_+|hypothetical-protein
MKKLIIAAALVIAAAGSSFAQRPEQKKVDPKERAEKMSQKLKSDLSLNEDQYAQILALNTAKTEKLEANKDLKKEEMKAKHEAMKVEREAYNANLKEILTQEQYIKFLEMKTEQKGEMRRKHAPRKRMKKEN
>CP029480.1|AWV99526.1|3854500_3855268_-|hypothetical-protein
MTIKLRILFVLLTSLVAFQSNGQKLWSVYGKVLNSQSKSPLSSLTVTNQRTEYVVVTNKSGDFFIRAAEGDSLIIRGIGFGETTIYWDKEVGHPTIGLDQQAIALEEVVVRDKRSETIEREIKAFLENPRNAKTMKRDIVGNLVRTTASGGLGGGAGISIDALYDLWSKDGKSKRKAAELEYQDLRRFYIELRYNKGKVAAITNLKDPDLSEFMEYCKLGDEIILNASDYDLTYQIMLCLREFNNTASFPVLKSN
>CP029480.1|AWV99527.1|3855273_3856506_-|peptidase-M14
MELTLTDLDLLSDYEKIKEPFFTKRRFKHADLVKLLEKFSFEKEVVGQSFEGRDIYKVKLGSGKTEVLLWSQMHGNEATATMAIVDILNYFQETSNGFVEDILNGLTLHLVPMLNPDGAERFIRRTAQQIDMNRDALALVCPESKLLKKLQEDIKPAFSFNLHDQNVRYSAGATKNQAAISFLATAYNEATEWNENRTKAMQVICEMNAVLQQIIPDKVGRFSDEFEPRAFGDNIQKWGSSLILIESGGYGTDHEKMYLRKLNFLIILKALESINVGAYKTKNLADYSAIPTNQKYLFDLLIRNVNMEGETVDIGINKDEVNIEKATDFEFNSIVEDIGDLSTFWGIETFDATGYTLSPLSDFLEILTSFKVKKEDLGRLEFEKKANFALTKNGELCHLVLNGEFVAVPS
>CP029480.1|AWV99528.1|3856496_3858590_-|hypothetical-protein
MSSIKGQIQSRSLWTFGFMGLIAVIIVWGILSVQNNDKYKNSIVEKNLIYEKDIPAMRGNIYGSDGKSLLATSVPYYYVGLDVKQSSEALFNQSVDELSKKLSAHFGDKTWNEYKSQIVSKRKSKKSRYLRLTGRRISHQEKMDISEFPLFKEGPYKGGGVFEKISTRSLPFNDMAKRTIGSLDRDTKTRGLFGIEFSYNNYLAGKNGKSLFKRLAGGVNQPLDSEINEEAIPGQDVVTTLDVNFQDIVEHALREKVTQTNANFGTAIVMEIATGEIKALANLSRRTRNNETSYIEDMNYAVLASTDPGSTFKLASMMAVLEKGNLSGKDWAANCTGTIMHRGKKFTCDHEHGNITVSEVFEKSCNIGVYKLIERVFGANGIDDYLTYISKYRLDKPIGFQLKGEKKPYFKNGADKTYSKFTLPWMSIGYESQISPIQMLAFYNAVANDGYWVEPFLVREIKEGNNTIEEYDNVKISKRIAPDDVIEMAKQMMKGVVTDGTAKGISSGFCKVAGKTGTAQKLDANGYNKGRYFTSFIGFFPADNPKYTAAVVIDEPRGDQVYASQVCAPVFRDIADKIFAYDVAIHPASKKAKQKNLIAKQQKSGMADDFQEIADELSIDMEPILVDGMVKFGIANNDSVYWKPIKATGGVPNVSGMTLKDALPILENKGYVVRHQGFGKVAEYGLVNSGVVNLILN
>CP029480.1|AWV99529.1|3858603_3858975_-|hypothetical-protein
MSFNVPKGQRKEPLMSRLANKFNLGEWISDTLNISEELPTSMLKKVGFAFMLVLTYIFFQHNFENLIRGLDKAEQEIKEKRAEYISHKSSYMFKSKHSQVSSALEQRGLLRNIEPPVKIVVVQ
>CP029480.1|AWV99530.1|3859103_3860021_-|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase
MSNTDYHVPVMLSECIEGLNINPDGIYVDITFGGGGHSKAIMDKLENGKLYSFDQDEDAKKNAENFDKSKFTFIQANFRHIKKFLRVHGVKKVDGILADLGVSSYQIDTPERGFSTRFDADLDMRMNRKAGPTAKDVINNYEVAELHKILGMYGEIKNAKTAAQAIDMARSGEPIKTIEELKKVLDTVAPKFKEFKYYAQVFQALRIEVNEEMKALEEFLFQVPDLLNTEGRLVVMSYHSLEDRMVKNYIKSGFLDGHLEKDFFGNVLKPLKGVTRKPITASDVELQKNPRSRSAKLRIAEKPEK
>CP029480.1|AWV99531.1|3860117_3861341_+|alkyl-hydroperoxide-reductase
MRKLLLMLSAFLLWQCQSENKKNIDGVWRAEVPTLIGPIPFNLEIETKNDTIKVYAINADEKLELDNAFFKNDSLHITMEVFDAEIVAHVSDKTMHGIYTKKLDDNSNRTGAFSASMGDSYRFTADSETAKHDVSGKWQVSFTEPEGKIYPAVGIFSQKGNKVTGTFLTSTGDYRFLDGNVVGDSLKLSCFDGTHIFLFKAKINENKLEGGRFSSSLLYKETWEGVKDDNAKLPDPDSLTFIKAGFDKFELSFKNTKGETISLSDAQYKDKVVLVQILGSWCPNCMDESKFYVKWLKENPEKDVEIIGLAFEKSTEPDIAYPKIDKMKKRFGMEYEVLLAGTIDKEDANKSLPMLNHIMSYPTTIYLDKKHHVRKIHTGFSGPGTGEYYAQFTEDFERFMELLISEE
>CP029480.1|AWV99532.1|3861416_3862607_+|MFS-transporter
MSSKEKLLLIVLACVNFTHIMDFMILMPLGPQLIDIFDINTQQFGFLVATYGVAAAISGFTLAFFADRFDRKKVLLFAYIGFVVGTFACAISPTFTILISARTITGLFGGMIGSQVLSIVADAFPYERRASAMGIIMMAFSLASVIGVPGGLYLATKFSWHAPFFTVGGLGIIVMILIWAFVPNVTAHLEQESAKQKKLEVLTNILKTPNQLWALALSVVIMLGHFSIIPYIAPSLVSNIGYKEDQIFLIYLVGGLLTIFSAPLVGKLADKRGKFPIFVTFAILSCIPIFLITNLIPTPIYVVLTISGLFFIFSNGRLIPTQAMVSGVVTPKQRGGFMAINSSVQLMAQAIASSIGGLIIIQREDGYLDHYDWVGYYAISMILLSIFIARKIKNIN
>CP029480.1|AWV99533.1|3862603_3863341_-|L-ribulose-5-phosphate-4-epimerase
MKTLQYIKTKNLKKYKNLKEECYEANLELPKLGLVLFTFGNVSAVDRKEGVFAIKPSGVPYEKLKVEDIVIMDYDAKVVEGNMRPSSDTKTHALLYKTWDDIGGITHTHSTYAVAWAQAGKNIPIFGTTHADHTHQDIPCAPVLSDEMIQGDYEFETGNQIINVFKERGLSHLEMEMVLLQNHGPFTWGKDAAKSVYNAAVLEEVAKMAQLTLAINPETPRLKETLKNKHFQRKHGKDAYYGQGC
>CP029480.1|AWV99534.1|3863463_3864894_-|L-arabinose-isomerase
MIKLADFEVWFITGSQHLYGEETLRQVDEHSEEIVRFFQASENIAVNVIFKPVVKTPEEISGMLNAANAQENCVGIITWMHTFSPAKMWINGLNALQKPLLHLHTQFNRDIPFADIDMDFMNLNQSAHGDREFGHILTKMNIKRKTVVGHWQDPEVLESINVWSRVAVAANEMKTLKVARFGDNMREVAVTDGDKVAAQMKFGFSVNTHPVGDLVAYINKVTNTEIKTLIEEYKSVYKMMPSLEEGAEKYESLVEAARIELGMKAFLEEGDFGAYTNTFEDLHGMRQLPGIGSQRMMAAGYGYGGEGDWKTSAMVRILKTMATGMKGGNSFMEDYTYHFNPENPMVLGSHMLEICPSISSSEVACEVHPLGIGGKEDPVRLVFNGDAGRAMNVSLVDMGDRFRLIVNLVQGLEVTEEFPKLPTARVMWRPEPSMKEGLKQWLEAGGAHHTVYSQNLSLEYMEDFARMFDLELVVIS
>CP029480.1|AWV99535.1|3864910_3865891_-|GTP-3',8-cyclase-MoaA
MLIDNHGRPITYLRLAVTDRCNLRCFYCMPEEGITFLPKPHLLTFEEMLRMVRMMAELGIKKVRITGGEPFVRKELMSFLRALVAIPGIEKVNITTNGVLTEHLVPELKALGISSINLSLDTLDRERFKEMTRRDELPNVLRTLDALLEHEIDTKINAVVMAGKNDQDILPLVGLSEKMPVSVRFIEEMPFNGSGLNEAAFMSYHKILDIIKEAHPSLAKLKDEASSTSYNYSIANHLGNVGVIAAYSRTFCGTCNRIRVTPTGTLKTCLYDDGVLNIRDLLRSNTDDVEIKEILTKVFTNRHKDGFEAEANRKSEVTESMTTIGG

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP029480_1	1.11|1324855|29|CP029480|CRT,CRISPRCasFinder,PILER-CR	1324855-1324883	29	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	86340-86368	4	0.862
CP029480_1	1.9|1324717|32|CP029480|CRT,CRISPRCasFinder,PILER-CR	1324717-1324748	32	NZ_CP012265	Cronobacter condimenti 1330 strain LMG 26250 plasmid pCCO1, complete sequence	119136-119167	7	0.781
CP029480_1	1.11|1324855|29|CP029480|CRT,CRISPRCasFinder,PILER-CR	1324855-1324883	29	NZ_CP017591	Pantoea stewartii subsp. stewartii DC283 plasmid pDSJ10, complete sequence	288274-288302	7	0.759
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	NZ_CP006684	Melissococcus plutonius S1 plasmid pMEPL_178, complete sequence	9259-9288	7	0.767
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	NZ_AP021886	Melissococcus plutonius strain DAT1033 plasmid pMP1, complete sequence	9259-9288	7	0.767
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	NZ_AP018525	Melissococcus plutonius strain DAT585 plasmid pMP1, complete sequence	9276-9305	7	0.767
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	NC_018265	Melissococcus plutonius DAT561 plasmid 1, complete sequence	189764-189793	7	0.767
CP029480_1	1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR	1324437-1324469	33	AP013489	Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S45-C81	2411-2443	8	0.758
CP029480_1	1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR	1324437-1324469	33	AP013488	Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S38-C82	310-342	8	0.758
CP029480_1	1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR	1324437-1324469	33	AP013486	Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S29-C73	9639-9671	8	0.758
CP029480_1	1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR	1324437-1324469	33	AP013487	Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S33-C83	18767-18799	8	0.758
CP029480_1	1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR	1324437-1324469	33	KP836356	Marinitoga camini virus 2, complete genome	13942-13974	8	0.758
CP029480_1	1.9|1324717|32|CP029480|CRT,CRISPRCasFinder,PILER-CR	1324717-1324748	32	NC_010393	Phage Gifsy-2, complete genome	14234-14265	8	0.75
CP029480_1	1.10|1324785|34|CP029480|CRT,CRISPRCasFinder,PILER-CR	1324785-1324818	34	NZ_CP031076	Bacillus mycoides strain BPN401 plasmid pl36, complete sequence	240-273	8	0.765
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	NZ_AP018939	Escherichia coli strain JSWP006 plasmid pJSWP006_1, complete sequence	32513-32542	8	0.733
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	NZ_CP044980	Bacillus thuringiensis strain BT62 plasmid pBT62B, complete sequence	2888-2917	8	0.733
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	NZ_MN328348	Salmonella enterica subsp. enterica serovar Enteritidis strain S14 plasmid pTS14, complete sequence	10932-10961	8	0.733
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	NZ_CP027156	Klebsiella pneumoniae strain AR_0363 plasmid unnamed4	151822-151851	8	0.733
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	NC_029050	Salmonella phage 21, complete genome	38731-38760	8	0.733
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	KR296685	UNVERIFIED: Salmonella phage 21, complete genome	38731-38760	8	0.733
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	AP013721	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22A-MedDCM-OCT-S45-C35, *** SEQUENCING IN PROGRESS ***	18847-18876	8	0.733
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	HG918041	Klebsiella pneumoniae Kp15 plasmid pENVA complete sequence	6563-6592	8	0.733
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	AP014427	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22-MedDCM-OCT-S28-C14, *** SEQUENCING IN PROGRESS ***, 3 ordered pieces	38335-38364	8	0.733
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	KY744240	Weissella phage PWc, complete genome	38681-38710	8	0.733
CP029480_4	4.1|3854313|30|CP029480|CRISPRCasFinder	3854313-3854342	30	AP013719	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22A-MedDCM-OCT-S33-C25, *** SEQUENCING IN PROGRESS ***	18520-18549	8	0.733
CP029480_1	1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR	1324437-1324469	33	CP009912	Borreliella chilensis strain VA1 plasmid lp54, complete sequence	50483-50515	9	0.727
CP029480_1	1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR	1324437-1324469	33	MN693109	Marine virus AFVG_25M321, complete genome	4290-4322	9	0.727
CP029480_1	1.12|1324920|34|CP029480|CRT,CRISPRCasFinder,PILER-CR	1324920-1324953	34	MW057859	Providencia phage PSTCR8lys, complete genome	18140-18173	9	0.735

1. spacer 1.11|1324855|29|CP029480|CRT,CRISPRCasFinder,PILER-CR matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 4, identity: 0.862

tataatatagaaataggcaaaag-acagtt	CRISPR spacer
aataataaaaaaataggcaaaagaacagt-	Protospacer
 ****** *.************* ***** 

2. spacer 1.9|1324717|32|CP029480|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP012265 (Cronobacter condimenti 1330 strain LMG 26250 plasmid pCCO1, complete sequence) position: , mismatch: 7, identity: 0.781

tatagaagggaatataccttcaaaaaaagtat-	CRISPR spacer
gaaaaaaaggaatataccatcaaaaaaa-catg	Protospacer
 * *.**.********** ********* .** 

3. spacer 1.11|1324855|29|CP029480|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP017591 (Pantoea stewartii subsp. stewartii DC283 plasmid pDSJ10, complete sequence) position: , mismatch: 7, identity: 0.759

tataatatagaaataggcaaaagacagtt	CRISPR spacer
aataatataaaaataggcataagactcag	Protospacer
 ********.********* *****    

4. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to NZ_CP006684 (Melissococcus plutonius S1 plasmid pMEPL_178, complete sequence) position: , mismatch: 7, identity: 0.767

accttttattcaacaaaacaatcttttcct	CRISPR spacer
cacttttatttaacaaaagaatctttttaa	Protospacer
  ********.******* ********.  

5. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to NZ_AP021886 (Melissococcus plutonius strain DAT1033 plasmid pMP1, complete sequence) position: , mismatch: 7, identity: 0.767

accttttattcaacaaaacaatcttttcct	CRISPR spacer
cacttttatttaacaaaagaatctttttaa	Protospacer
  ********.******* ********.  

6. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to NZ_AP018525 (Melissococcus plutonius strain DAT585 plasmid pMP1, complete sequence) position: , mismatch: 7, identity: 0.767

accttttattcaacaaaacaatcttttcct	CRISPR spacer
cacttttatttaacaaaagaatctttttaa	Protospacer
  ********.******* ********.  

7. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to NC_018265 (Melissococcus plutonius DAT561 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.767

accttttattcaacaaaacaatcttttcct	CRISPR spacer
cacttttatttaacaaaagaatctttttaa	Protospacer
  ********.******* ********.  

8. spacer 1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR matches to AP013489 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S45-C81) position: , mismatch: 8, identity: 0.758

aaatttgtcaaaaaacaaggagagaaaattaaa	CRISPR spacer
ttaactaacaaaaaacaaggagagagaatgaaa	Protospacer
  * .*. *****************.*** ***

9. spacer 1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR matches to AP013488 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S38-C82) position: , mismatch: 8, identity: 0.758

aaatttgtcaaaaaacaaggagagaaaattaaa	CRISPR spacer
ttaactaacaaaaaacaaggagagagaatgaaa	Protospacer
  * .*. *****************.*** ***

10. spacer 1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR matches to AP013486 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S29-C73) position: , mismatch: 8, identity: 0.758

aaatttgtcaaaaaacaaggagagaaaattaaa	CRISPR spacer
ttaactaacaaaaaacaaggagagagaatgaaa	Protospacer
  * .*. *****************.*** ***

11. spacer 1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR matches to AP013487 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S33-C83) position: , mismatch: 8, identity: 0.758

aaatttgtcaaaaaacaaggagagaaaattaaa	CRISPR spacer
ttaactaacaaaaaacaaggagagagaatgaaa	Protospacer
  * .*. *****************.*** ***

12. spacer 1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR matches to KP836356 (Marinitoga camini virus 2, complete genome) position: , mismatch: 8, identity: 0.758

aaatttgtcaaaaaacaaggagagaaaattaaa	CRISPR spacer
agaagttggaaaaaacaaagagggaaaattaaa	Protospacer
*.*  *   *********.***.**********

13. spacer 1.9|1324717|32|CP029480|CRT,CRISPRCasFinder,PILER-CR matches to NC_010393 (Phage Gifsy-2, complete genome) position: , mismatch: 8, identity: 0.75

tata-gaagggaatataccttcaaaaaaagtat	CRISPR spacer
-acaccaagggaatataccaccaaaaaaaacaa	Protospacer
 *.*  ************* .********..* 

14. spacer 1.10|1324785|34|CP029480|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP031076 (Bacillus mycoides strain BPN401 plasmid pl36, complete sequence) position: , mismatch: 8, identity: 0.765

aattaaaggctttgaaataagtctaaaaataaaa	CRISPR spacer
aattgttttctttgaaataagtctaataacaaac	Protospacer
****.    ***************** **.*** 

15. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to NZ_AP018939 (Escherichia coli strain JSWP006 plasmid pJSWP006_1, complete sequence) position: , mismatch: 8, identity: 0.733

accttttattcaacaaaacaatcttttcct	CRISPR spacer
gcctttttttcaacaaaacaatattcgtgc	Protospacer
.****** ************** **. . .

16. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to NZ_CP044980 (Bacillus thuringiensis strain BT62 plasmid pBT62B, complete sequence) position: , mismatch: 8, identity: 0.733

accttttattcaacaaaacaatcttttcct	CRISPR spacer
ttatttttttcaacaaaaaaatcttttaaa	Protospacer
 . **** ********** ********   

17. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to NZ_MN328348 (Salmonella enterica subsp. enterica serovar Enteritidis strain S14 plasmid pTS14, complete sequence) position: , mismatch: 8, identity: 0.733

accttttattcaacaaaacaatcttttcct	CRISPR spacer
gcctttttttcaacaaaacaatattcgtgc	Protospacer
.****** ************** **. . .

18. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to NZ_CP027156 (Klebsiella pneumoniae strain AR_0363 plasmid unnamed4) position: , mismatch: 8, identity: 0.733

accttttattcaacaaaacaatcttttcct	CRISPR spacer
ggctttttttcaacaaaacattcttaacta	Protospacer
. ***** ************ ****  *. 

19. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to NC_029050 (Salmonella phage 21, complete genome) position: , mismatch: 8, identity: 0.733

accttttattcaacaaaacaatcttttcct	CRISPR spacer
ccagcccattcaccaagacaatcttttcct	Protospacer
 *  ...***** ***.*************

20. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to KR296685 (UNVERIFIED: Salmonella phage 21, complete genome) position: , mismatch: 8, identity: 0.733

accttttattcaacaaaacaatcttttcct	CRISPR spacer
ccagcccattcaccaagacaatcttttcct	Protospacer
 *  ...***** ***.*************

21. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to AP013721 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22A-MedDCM-OCT-S45-C35, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.733

accttttattcaacaaaacaatcttttcct	CRISPR spacer
aatgtaatttcaacaaaacaatctttacca	Protospacer
* . *   ****************** ** 

22. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to HG918041 (Klebsiella pneumoniae Kp15 plasmid pENVA complete sequence) position: , mismatch: 8, identity: 0.733

accttttattcaacaaaacaatcttttcct	CRISPR spacer
ggctttttttcaacaaaacattcttaacta	Protospacer
. ***** ************ ****  *. 

23. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to AP014427 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22-MedDCM-OCT-S28-C14, *** SEQUENCING IN PROGRESS ***, 3 ordered pieces) position: , mismatch: 8, identity: 0.733

accttttattcaacaaaacaatcttttcct	CRISPR spacer
aatgtaatttcaacaaaacaatctttacca	Protospacer
* . *   ****************** ** 

24. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to KY744240 (Weissella phage PWc, complete genome) position: , mismatch: 8, identity: 0.733

accttttattcaacaaaacaatcttttcct	CRISPR spacer
tagggttattcagcaacacaatcttttcat	Protospacer
     *******.*** *********** *

25. spacer 4.1|3854313|30|CP029480|CRISPRCasFinder matches to AP013719 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22A-MedDCM-OCT-S33-C25, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.733

accttttattcaacaaaacaatcttttcct	CRISPR spacer
aatgtaatttcaacaaaacaatctttacca	Protospacer
* . *   ****************** ** 

26. spacer 1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR matches to CP009912 (Borreliella chilensis strain VA1 plasmid lp54, complete sequence) position: , mismatch: 9, identity: 0.727

---aaatttgtcaaaaaacaaggagagaaaattaaa	CRISPR spacer
ctcagac---tcaaaaaacaatgagagaagattatt	Protospacer
   *.*.   *********** *******.****  

27. spacer 1.5|1324437|33|CP029480|CRT,CRISPRCasFinder,PILER-CR matches to MN693109 (Marine virus AFVG_25M321, complete genome) position: , mismatch: 9, identity: 0.727

aaatttgtcaaaaaacaaggagagaaaattaaa	CRISPR spacer
gactgaaggaaaaaacaaggataggaaattaaa	Protospacer
.* *  .  ************ **.********

28. spacer 1.12|1324920|34|CP029480|CRT,CRISPRCasFinder,PILER-CR matches to MW057859 (Providencia phage PSTCR8lys, complete genome) position: , mismatch: 9, identity: 0.735

tttttactgagtatcaacaatgatatttcagctc	CRISPR spacer
ttgctttacagcatcaacaatgatatttccgcta	Protospacer
** .* .  **.***************** *** 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	5305143 : 5312972	8	Streptococcus_phage(33.33%)	tRNA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>CP029480|5305143:5312972|DBSCAN-SWA
ATCAGCTATACAAATCGCTGCTCAAATAACGGTCTCCACGGTCACAAACTATGAAAACGATATTGCCGTGCTCTAATTCTCCAGCTAATTTAATTGCCGCTGAGGCCGCACCTCCACTGCTCATTCCAGAAAAAATAGATTCTACTTTTGCTAAGTCTCTAGCTGTTTTAGCAGCTATTTCTGTAGAAATATCAAAAACTCTATCGACACGCGACTCGTCAAATATTTTTGGCAAATATTCCTTAGGCCAGCGTCTAATTCCAGGAATAGAAGAACCCTCGGTTGGTTGACAACCTACTATTTGAATATTAGCGTTTTGCTCTTTTAAATACATCGAAGTACCCATAATAGTACCTGTGGTACCCATAGCACTCACAAAATGAGTAATCTTACCATCTGAATCCCTCCAAATCTCAGGCCCCGTAGTTTTATAATGTGCTAGGTAATTATCAGGGTTGGCAAACTGGTTAAACTGAAAATAGCCATCCTCTTTGCCTTTTTCATCGGCATAGTCTCGGCATGTTTCTATACCGTCTAGTAGCGTTACTTTTGCTCCGTAAGCTTCCATCGTTTTGGCACGTTCTACCGTACTGTTCTTCGGCATTACCAGTTCTATTTTCAAGTCATATTGACAAGCTATCATAGCTAAGGCTATGCCCGTATTGCCACTGGTGGCTTCTATCAACTTATCTCCCGGCTTGATATCCCCTCTTTCTAAAGCAGACTGAATCATATTTAAAGCCGCTCTATCTTTTACAGAACCTCCAGGATTATCGCCTTCTAATTTAGCGTAAATCTTAACCTTAGGGTTATCACTGTTTTTATAATGTGGGTTGAGCCTTTTCAGCTCTACTAAAGGAGTATTTCCTACTAAATCTATTATGGTAGCCATATTATGCTAATTCTCTTTCTTTAACTTCTATTTCTGGTTTGTGATACACTATGCTATTGGCAGGGACACTTTTGGTGAGCCAAACATTACCACCGATAATGCTATTAGCACCAATGACCGTTTGCCCTCCCAGTATGGTGGCATTGGCATAAATCACGGTTCCGTCTTCTACCGTAGGATGTCTTTTTACATTTGCCAAAGCTTTATCTACACTTAGTGCTCCCAAAGTTACCCCTTGATAAATTTTCACGTTTTCGCCAATGATAGACGTTCCGCCAATCACTATTCCTGAGCCATGGTCAATGAAGAAATTTTCTCCTATCTGTGCACCTGGGTGTATATCAATTCCGGTTTTAGAGTGTGAAAACTCTGTCAATATTCTAGGAATTAATGGGATGTCCATTTTTAAAAGTAAATGAGCCAACCTGTAAAATGAAATGGCATGAAAACCCGGATATGCTCTAATAATTTCAAACTCGCTAGTAGCGGCAGGGTCACCTGCCATTATAGCCTTTACGTCGGCACTTAATAGCCTAAAAAGCTCTGGAAGCGACTCTTTGAAAAGCGTTGCTCTTTCGTCGTTGTCACAATCTTTGCATTTATCTGTCGCATTCAACATGATTTTTAACTCATTTCCCAAGTTCCAGATTTCACCCTCTATCTCGTCTACACTAGGGAAAAAATCTTTAGCCTGCTCTGGAAATAAAAGATGAAAAACCTCAGTAGCCCACTCCCCTATTTTTTTGGTTTGTGGCACAGCTTCAGTCTTTTGATGCTTTTCGTAGATATGTTGCAAAAACTGCTTTTCCATTTATTTAAATTTTCATTTCACTTTTAACGAACAATTTGCCTGCCACGTTCAATTCTTTAAACAGCTTTTTAATAAACCTTAGCCTACTTGAACTAATATCAAATCATGCCGAGCCTTCCTTCATCAGAACTTAATAGTGACTAAATGTAATTCAATGTTGCATAAAAATGAGCTAAAACTGTCAATCTGTCAGCCTTTTGCCAATTGGAATATCCTTTGTTCAGTCTTTAGTGCTGAAAGGCAAATGAAAATAGAATTTTTAAAACAAAAATATAAGATAACATGTCAACTGAAAAAGGTAGTATTTCCATTAATACGGAAAACATCTTCCCGATAATCAAGAAGTTTTTATACTCTGACAATGAAATTTTCTTAAGAGAATTAGTTTCTAATGCGGTAGACGCCACTCAAAAAATCAAAAAACTTGCTTCAATGGGCAAATTTGATGGTGAGTTGGGAGATTTAAAAATTAAAGTAGCGGTAGACAAAGAAGCTAAAACCATCACTATTTCTGACAGAGGTTTAGGAATGAGTGCTGAAGAGGTGAAAAAGTACATTAACCAAATAGCCTTTTCTGGTGCTAAAGACTTCTTAGAAAAATATAAAGATGTAGATGATAAGAACCCGATAATTGGTCAATTTGGACTTGGTTTTTACTCAGCCTACATGGTGGCTAAAGAGGTAGAGATTCATACAAAATCTTACCAAGACGCTCCTGCCGTAAAATGGCTATGCGACGGAACTACGGAATATGAAATTTCTGATATTGAAAAAACAGAAAGAGGTACAGACATTATTCTTCATGTAGCAGAAGACTCTGAAGAGTTTTTAGAAGAAGCTAGAATTGAAACCATCCTTAATAAGTATGGTAAATTCTTACCTGTAGAAATTGAGTTTAAAGAAGAGGTTATCAACAACCCTGCTCCAATCTGGATTAAAGCACCTTCTGACCTTAAAGATGAAGATTACATAGCTTTTTACAAAGAGCTTTACCCTGCTGGTGAAGACCCACTTTTCTGGATTCATTTAAATGTAGATTACCCTTTCAATTTGACAGGTGTACTTTACTTCCCGAAAATCAAGCAAGATTTCCAACTAAGCAGAGAAGGTATTCAGCTATATAGTCGTCAAGTATTCATCACGGATAATGTAAAAGACATTGTTCCTGAATTCTTACAGTTACTTCACGGTGTAATTGACTCTCCAGATATTCCGTTAAACGTATCTAGAAGTTATCTTCAAGCTGACGGAAACGTTAAGAAAATCAATAGCCATATCACTAAAAAAGTAGCTGATAAACTTGGCGAGCTTTTCAATAATGACCGTAAGGCTTTTGAAGAGAAATGGGATAGCATTGGCCTTTTTGTGAAATACGGAATTATCTCTGATGATAAATTCTACGATAGAGCTCAAAACTTCTTGTTGTTCAAAAACACAGAGAATGAGTACTTCACTCCGGAAGAATACAAAACGAAAGTAGAGGCTCTTCAAAAAGACAAAGACGAGAACACGATTATTCTTTATACTTCCGATGCTGAAAAGCAAGATGCTTTCATCAAAGGAGCAAAGAAGCGTGAGTTTGACGTAATAGTTCTTAATGATGTGCTTGACCCTCACTTCATAAACACCATGGAGCAAAAACTTGAAAAAGTTAGCTTCAAACGTGTGGATGGAGATTCTTTAGACAAACTAGTGGACAAAGGTTTAACGTCTGAGTCTGTTTTAGGAGAAAAAGAAAAGGAAAAAGTAGAAGGTCTTTTCAAAGAATTGGCTGGAAACAACGTGGTTCAGATAGAGGCTCTTCCTGCTGACGATGCTCCTGTGAGCATAGTACAGCCTGAGTTTATGCGTAGATACATGGACATGAGCAAGCTTAATGGCCAAGCTGGCATGATGGGTAATATGCCAACCATGTACAATTTGGTAGTAAACGGAAACAGTCCAATTATAGCGAAGATGCTTAAGATGAAAGGTGAAGACAGAAGACAGACCTACGCAAAACAATTGCACGATTTAGCTCTTCTTTCTCAAGGCATGCTTTCAGGTGGTAACTTGACGGACTTTGTGAATAGAACTTTTGAAGAGATGGCTTAATTTTTTTCGATATTCGTTTTTTGATATTGGATATTAGTTGTTCTTCAATGACTATAGTTCGATATTAGGGGCTTACGCCTTATTAATTAGACCTCGTGGATTTATTCTGCGAGGTCTTTTATTGTTCTAGAAACTAATTATTCCCTACATTTGTTCACTTATAGTAAACTTTATGTTTAATATTATAAATAGAAGAACCATTTTGCACTACTGCACCATGTACCTTAAAGCAAAAAATGCTTTGCTAGAATGGTATCATGAAGTAAAGAGTGCCGAATTTGAAAGTTTCCAAGAACTAAAACAGAGCTATGGAAGTGCAAGTATAGTGGGAGACGACAGAGTAGTATTTAACCTAATGGGGAATCAATTTAGGTTAGTGGTAAGATTTGTATTTCCATTTAAAACAGTTCAAATTAAATGGTTTGGAACACATAAGGAATACGACAAGATTGATGTGACAACTATTAAATTCAAGAAAAAATGAAAAGCATAACTTTAAAACCTATTCGCACAGAGGATGAATATGAAGTTTTTTTAGAGTTTGTCGATGAACAATTTGACAAAAAAGTAACTAAAAACTCACCAGAGGGTGATGTTTTAGAAATGGCTTTACTTCTAATCAAGGATTACGAGGATAAGCATTATGCTATTCCGTACCCTGACCCTATTGAAGCCATTAAGGGAAAAATGGCGGACGAGGGCATTAAGAGTAAAGACCTCATTGGTCTTGTAGGTAGCAAAAGCTACATTTCAGCTATTCTAAACAGGAAGAAACCCTTAACATTAAAGATTGCACGAATTTTCCATGAAAAATTGGGTATTCCTGCTGAGGTTTTACTTGGGTAGTTACCCTTCTCTGGATTAAGGACTATTTACTTGAGATACGCATACTCCTTCAATAACTCCACCTCCACATCGTAACCTTGATACTGGCTTATGAATTGAAAGCTATCATTATACGCTTCTTCGGAGAGCCAAACTTTGTTTTTTTCAAGACCTGATAGAATTAGTAAGATATCTTGGTCTAGCCTTAATCCTTAGTAAAGTAACCAGATTGGTCATAACGCTCATACACTGATATAGCGGAATTTTTGGTTTGATACTCTGTATCTGTAAGTGCAGTTTTGCTTGCCTCTAAACTTGCTTTTATAAGCTCTTTCGTCAAGTTTATTTCTAGTTCTGTAACCTTTGAGATACTCGCAGTGAAGCTATGCTCTACACCGGCATCTGTAGTTAGTGTTACTTTGTTTGCTATTAATGTATAGGTTCCTTTGATAGTCCCAGCTTTAAAAGAATCGAAGCCATAATCTCCTATGGAGAATTTATTCATGTTGAAAGTACCATCTTTCATAAAAACCACTTGACTGCCATCTGGTGAATTAATAGTAGAATTCAGAACATTAGCTCCGCTTTTCTGACTAACAGTAAATATATAATCTGACTCCCAAGTACCCACAATATTTAAAGTAGATTGTTGCTCTGATTCTTGCTCTGGCTCCATCTCTGAATCAGAATCCTTTGTACATGAAAAAGTGAAAATTATCAGAAAGGCGAAAAGTAGATTTTTCATCGATGAATTGTTAAACGTATTTTCATAAAACTCATTCAATAATCATACCTGAATCTAGACTTTGAACTTAAACTTCTGAAGACTCTAATTCCACAAACCTTAAATCCAAAACCGCCTCTTTTACTTCCTCTAATAGAGAAAGCCTCACCTCAATGGTCAAAATGTATTTATCCGTATAGTCTTGCGATAAAATATTCAACTCATACTTCTTAATTATCCGCATCACCTCATTCATGTATTGAATATTAAAAGAAAGTTGAAGTGACTCGTTTATAGTTCTTTCTTCTAGTTTGACTTCGTCCAAAGCTTCTATGCTCGCCATTTTGTACGCATTGATAAGTCCTGGCACCCCTAAAAGCGTTCCGCCAAAATACCTAACCACCACTATAAACACATTTCTTAAGTTTTGCGACAGCAAAACATTCAATATTGGCTTGCCTGCCGAACCCGAAGGCTCTCCATCATCATAAGCCCTAAAATTGTCATCATTGATTCCTAAGCGGTACGCAAAACAATGATGCCGTGCTTTAGGATGAAGTTTTTTAGCCTCATCTAAATGGAATTTAACATCGTCTTCGTCAGCCACCGGGAATGCAAAACCATAGAACTTACTTCCCTTATCTTTAAATAAACTTACCGATGGTTTAGAAATAGTGAAATACGTATCAGAAATAGACATGTTTTAAGGAAATCTTAAGTAATTTTGCGGCCTTATAAAGTCAAATTTAGGCTTTAATTTTAAAGCTATAGACCAAAAGAAGGCATACTCTCATATTTAAGAGAAGTAAGCAAGGAGATAACATAATGGCAAACGAGGAAAAAGAAAAAAGCTTAAACTTTATTGAGGAGATAGTTGAAAACGACTTATCCTCCGGTAAACACAAATCTATACTAACCAGGTTTCCACCTGAGCCTAATGGCTATTTACATATTGGCCATGCAAAATCTATTTGTTTAAACTTTGGTTTGGCTGAGTCATATGGCGGAAAAACCAATTTACGTTTTGATGACACTAATCCAGTGACGGAAGACACCGAATACGTAGATTCTATAAAAGAGGACGTAAAATGGTTGGGCTTTGACTGGGCTAGTGAGCATTATGCTTCAGATTATTTTGACACACTTTATGAGTATGCCGAAAAACTGATAAACCTAGGACTAGCTTATGTAGACGACAGTAACTCAGAAGAGCTTGCTGCTCAAAAAGGAACACCAACTACCCCTGGAACTAACAGTCCGTTTAGGGATAGAAGTATAGAAGAAAACCTTACGCTTTTCAGAGAAATGCGTGAAGGAAAACATGAGGAAGGTAGTAAAGCATTGAGAGCCAAAATTGACATGGCCTCTACCAACATGCTTATGCGTGACCCAATCATCTACAGAATAAAATTTGCGAAGCATCACCGTACTGGCGACAAATGGTGCATCTATCCTATGTATGATTTGGCTCATGGCCAGTCAGACTCCATAGAAGAAATAACCCACTCTGTATGTACGCTGGAGTTTGTAGCTCACAGAGAATTGTACGATTGGTTTATTGCCAAATTAGAAATATTCCCTTCAAAACAGTACGAGTTTGCTCGTTTAAATCTTGGCTATACCTTAATGAGCAAGCGTAAGCTTAGACTTTTGGTAGAAGAAAACCATGTCAATGGTTGGGACGACCCAAGAATGCCTACTATTTCTGGACTAAGAAGAAGAGGATACACACCAAAATCAATTAGAGATTTCTGCGATAGAATAGGAATAGCAAAACGCGACAACATGATTGACGCTAGTTTGTTAGAGTTCTTTATCAAAGATCATCTAAACAAAATCTCTTCTAGAGTGATGGCGGTAACTGACCCATTAAAAGTTACCATTACTAATTTCCCTGAAGGTCAAACGGAAGATTGCGAAATTGACAATAATCCTGAAGATGAAAACAGCGGGAGCCGAATGGTGCCTTTCGACAGAGAGATTTTCATTGAAAAATCAGATTTCTTAGAAGAAGCTCCTAAAAAATATTTCCGCTTAAAACCAGGTGGAGTAGTAAGACTTAAAGGAGCCTACATTATTCAGTGCGACGACATTGTTAAAGATGAAAACGGCGAAGTAATAGAGCTAAAATGTAGCTTTATAGAAAACAGTAAAAGTGGACAAGACACTTCTGGTGTAAAATGCAAAGGCGTAATACACTGGGTAAGTCAGAAAAACAACGTGCCATTAGAACTTCGCGTTTACGATAGACTTTTCAAAGAAGAAGATGTGGCAGGTTATGATGGTGACTTTAGAGACATTCTTAACGAAAACTCTTTAGAAGTATTAAAAGCCTACGGCGAGCCAAGTTTGAAAGACGCTAAGCTTGATGATAAATTTCAATTTATACGTAAGGGTTATTATGTACTGGACAAAGACAGCACAGAAAACCAGATAATTTTCAATCAGACTGTAGGCATGAGAGACAGCTGGAAAAAGAACTAG

Protein sequences of DBSCAN-SWA_1

>CP029480|5305143:5312972|5310576_5311188_-|AWW00671.1|DBSCAN-SWA
MSISDTYFTISKPSVSLFKDKGSKFYGFAFPVADEDDVKFHLDEAKKLHPKARHHCFAYRLGINDDNFRAYDDGEPSGSAGKPILNVLLSQNLRNVFIVVVRYFGGTLLGVPGLINAYKMASIEALDEVKLEERTINESLQLSFNIQYMNEVMRIIKKYELNILSQDYTDKYILTIEVRLSLLEEVKEAVLDLRFVELESSEV
>CP029480|5305143:5312972|5305143_5306034_-|AWW00666.1|DBSCAN-SWA
MATIIDLVGNTPLVELKRLNPHYKNSDNPKVKIYAKLEGDNPGGSVKDRAALNMIQSALERGDIKPGDKLIEATSGNTGIALAMIACQYDLKIELVMPKNSTVERAKTMEAYGAKVTLLDGIETCRDYADEKGKEDGYFQFNQFANPDNYLAHYKTTGPEIWRDSDGKITHFVSAMGTTGTIMGTSMYLKEQNANIQIVGCQPTEGSSIPGIRRWPKEYLPKIFDESRVDRVFDISTEIAAKTARDLAKVESIFSGMSSGGAASAAIKLAGELEHGNIVFIVCDRGDRYLSSDLYS
>CP029480|5305143:5312972|5309428_5309785_+|AWW00992.1|DBSCAN-SWA
MTLKPIRTEDEYEVFLEFVDEQFDKKVTKNSPEGDVLEMALLLIKDYEDKHYAIPYPDPIEAIKGKMADEGIKSKDLIGLVGSKSYISAILNRKKPLTLKIARIFHEKLGIPAEVLLG
>CP029480|5305143:5312972|5306035_5306845_-|AWW00667.1|DBSCAN-SWA
MEKQFLQHIYEKHQKTEAVPQTKKIGEWATEVFHLLFPEQAKDFFPSVDEIEGEIWNLGNELKIMLNATDKCKDCDNDERATLFKESLPELFRLLSADVKAIMAGDPAATSEFEIIRAYPGFHAISFYRLAHLLLKMDIPLIPRILTEFSHSKTGIDIHPGAQIGENFFIDHGSGIVIGGTSIIGENVKIYQGVTLGALSVDKALANVKRHPTVEDGTVIYANATILGGQTVIGANSIIGGNVWLTKSVPANSIVYHKPEIEVKERELA
>CP029480|5305143:5312972|5307127_5308939_+|AWW00668.1|DBSCAN-SWA
MSTEKGSISINTENIFPIIKKFLYSDNEIFLRELVSNAVDATQKIKKLASMGKFDGELGDLKIKVAVDKEAKTITISDRGLGMSAEEVKKYINQIAFSGAKDFLEKYKDVDDKNPIIGQFGLGFYSAYMVAKEVEIHTKSYQDAPAVKWLCDGTTEYEISDIEKTERGTDIILHVAEDSEEFLEEARIETILNKYGKFLPVEIEFKEEVINNPAPIWIKAPSDLKDEDYIAFYKELYPAGEDPLFWIHLNVDYPFNLTGVLYFPKIKQDFQLSREGIQLYSRQVFITDNVKDIVPEFLQLLHGVIDSPDIPLNVSRSYLQADGNVKKINSHITKKVADKLGELFNNDRKAFEEKWDSIGLFVKYGIISDDKFYDRAQNFLLFKNTENEYFTPEEYKTKVEALQKDKDENTIILYTSDAEKQDAFIKGAKKREFDVIVLNDVLDPHFINTMEQKLEKVSFKRVDGDSLDKLVDKGLTSESVLGEKEKEKVEGLFKELAGNNVVQIEALPADDAPVSIVQPEFMRRYMDMSKLNGQAGMMGNMPTMYNLVVNGNSPIIAKMLKMKGEDRRQTYAKQLHDLALLSQGMLSGGNLTDFVNRTFEEMA
>CP029480|5305143:5312972|5309111_5309423_+|AWW00669.1|DBSCAN-SWA
MFNIINRRTILHYCTMYLKAKNALLEWYHEVKSAEFESFQELKQSYGSASIVGDDRVVFNLMGNQFRLVVRFVFPFKTVQIKWFGTHKEYDKIDVTTIKFKKK
>CP029480|5305143:5312972|5309969_5310509_-|AWW00670.1|DBSCAN-SWA
MKNLLFAFLIIFTFSCTKDSDSEMEPEQESEQQSTLNIVGTWESDYIFTVSQKSGANVLNSTINSPDGSQVVFMKDGTFNMNKFSIGDYGFDSFKAGTIKGTYTLIANKVTLTTDAGVEHSFTASISKVTELEINLTKELIKASLEASKTALTDTEYQTKNSAISVYERYDQSGYFTKD
>CP029480|5305143:5312972|5311313_5312972_+|AWW00672.1|tRNA|DBSCAN-SWA
MANEEKEKSLNFIEEIVENDLSSGKHKSILTRFPPEPNGYLHIGHAKSICLNFGLAESYGGKTNLRFDDTNPVTEDTEYVDSIKEDVKWLGFDWASEHYASDYFDTLYEYAEKLINLGLAYVDDSNSEELAAQKGTPTTPGTNSPFRDRSIEENLTLFREMREGKHEEGSKALRAKIDMASTNMLMRDPIIYRIKFAKHHRTGDKWCIYPMYDLAHGQSDSIEEITHSVCTLEFVAHRELYDWFIAKLEIFPSKQYEFARLNLGYTLMSKRKLRLLVEENHVNGWDDPRMPTISGLRRRGYTPKSIRDFCDRIGIAKRDNMIDASLLEFFIKDHLNKISSRVMAVTDPLKVTITNFPEGQTEDCEIDNNPEDENSGSRMVPFDREIFIEKSDFLEEAPKKYFRLKPGGVVRLKGAYIIQCDDIVKDENGEVIELKCSFIENSKSGQDTSGVKCKGVIHWVSQKNNVPLELRVYDRLFKEEDVAGYDGDFRDILNENSLEVLKAYGEPSLKDAKLDDKFQFIRKGYYVLDKDSTENQIIFNQTVGMRDSWKKN

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWW00666.1|5305143_5306034_-	cysteine synthase B	A0A1X9I5K7	Streptococcus_phage	2.3e-46	38.6
AWW00667.1|5306035_5306845_-	serine acetyltransferase	NA	NA	NA	NA
AWW00668.1|5307127_5308939_+	molecular chaperone HtpG	A0A1B1ISV4	uncultured_Mediterranean_phage	1.2e-49	26.4
AWW00669.1|5309111_5309423_+	addiction module toxin RelE	A0A0P0ZE17	Stx2-converting_phage	2.9e-09	34.8
AWW00992.1|5309428_5309785_+	transcriptional regulator	A0A0P0ZCT8	Stx2-converting_phage	1.6e-14	36.6
AWW00670.1|5309969_5310509_-	hypothetical protein	NA	NA	NA	NA
AWW00671.1|5310576_5311188_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	1.5e-17	34.2
AWW00672.1|5311313_5312972_+|tRNA	glutamine--tRNA ligase	A0A222YZ70	Escherichia_phage	1.8e-177	55.6