CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP021912	Erythrobacter sp. KY5 chromosome, complete genome	1 crisprs	DEDDh,RT,DinG,csa3	0	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP021912_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021912_2

3281219-3281313

Orphan

Consensus_repeat	Method
CCGAAGCTGGACGTGCTGCCGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP021912_2

>merge|CP021912|2|3281219-3281313|CRISPRCasFinder
CCGAAGCTGGACGTGCTGCCGCCCGAACTGCTGCTCGACGAAGAACCCGACGAGCTGGACGATGACGATCCACCGAAGCTCGACGTGCTGCCGCC

>CP021912|2|2|3281219-3281313|CRISPRCasFinder
CCGAAGCTGGACGTGCTGCCGCC	CGAACTGCTGCTCGACGAAGAACCCGACGAGCTGGACGATGACGATCCA
CCGAAGCTCGACGTGCTGCCGCC

Protein	Signature genes	Signature genes Name	Protein_function
CP021912.1\|AWW75828.1\|3274469_3275183_+\|twin-arginine-translocation-pathway-signal	unknown	unknown	gnl\|CDD\|379310
CP021912.1\|AWW75837.1\|3284995_3285604_-\|Holliday-junction-branch-migration-protein-RuvA	unknown	unknown	gnl\|CDD\|234645
CP021912.1\|AWW75836.1\|3284477_3284999_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376874
CP021912.1\|AWW75830.1\|3276758_3277655_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|223769
CP021912.1\|AWW75839.1\|3287040_3288069_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372909
CP021912.1\|AWW75832.1\|3280486_3280960_+\|rhodanese	unknown	unknown	gnl\|CDD\|238089
CP021912.1\|AWW75835.1\|3284074_3284464_-\|hypothetical-protein	unknown	unknown	unknown
CP021912.1\|AWW75831.1\|3277804_3280477_+\|aconitate-hydratase-1	unknown	unknown	gnl\|CDD\|236445
CP021912.1\|AWW75841.1\|3289312_3290182_+\|epimerase	unknown	unknown	gnl\|CDD\|223528
CP021912.1\|AWW75826.1\|3272006_3272930_+\|histone-deacetylase	unknown	unknown	gnl\|CDD\|212519
CP021912.1\|AWW75823.1\|3269790_3270939_+\|4-hydroxy-3-methylbut-2-en-1-yl-diphosphate-synthase	unknown	unknown	gnl\|CDD\|234737
CP021912.1\|AWW75824.1\|3270945_3271449_+\|protein-disulfide-isomerase	unknown	unknown	gnl\|CDD\|379399
CP021912.1\|AWW75829.1\|3275179_3276574_-\|L,D-transpeptidase	unknown	unknown	gnl\|CDD\|225536
CP021912.1\|AWW75842.1\|3290368_3290935_+\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
CP021912.1\|AWW75838.1\|3285906_3286992_+\|chorismate-synthase	unknown	unknown	gnl\|CDD\|235438
CP021912.1\|AWW75833.1\|3281566_3282436_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236766
CP021912.1\|AWW75827.1\|3272971_3274420_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224983
CP021912.1\|AWW75834.1\|3283037_3284078_-\|Holliday-junction-branch-migration-DNA-helicase-RuvB	unknown	unknown	gnl\|CDD\|234619
CP021912.1\|AWW75825.1\|3271464_3272007_+\|manganese-efflux-pump-MntP	unknown	unknown	gnl\|CDD\|308338
CP021912.1\|AWW75840.1\|3288170_3289316_+\|fatty-acid-desaturase	unknown	unknown	gnl\|CDD\|239584

Protein	Function_ID	Function_description	E-value
CP021912.1\|AWW75828.1\|3274469_3275183_+\|twin-arginine-translocation-pathway-signal	gnl\|CDD\|379310	pfam13645, YkuD_2, L,D-transpeptidase catalytic domain. This family is related to pfam03734.	1.94087e-46
CP021912.1\|AWW75837.1\|3284995_3285604_-\|Holliday-junction-branch-migration-protein-RuvA	gnl\|CDD\|234645	PRK00116, ruvA, Holliday junction branch migration protein RuvA.	6.74241e-75
CP021912.1\|AWW75836.1\|3284477_3284999_-\|hypothetical-protein	gnl\|CDD\|376874	pfam02635, DrsE, DsrE/DsrF-like family. DsrE is a small soluble protein involved in intracellular sulfur reduction. This family also includes DsrF.	8.29264e-14
CP021912.1\|AWW75830.1\|3276758_3277655_+\|EamA-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	1.76305e-08
CP021912.1\|AWW75839.1\|3287040_3288069_-\|hypothetical-protein	gnl\|CDD\|372909	pfam14096, DUF4274, Domain of unknown function (DUF4274). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, and is approximately 80 amino acids in length.	1.85743e-09
CP021912.1\|AWW75832.1\|3280486_3280960_+\|rhodanese	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	1.21294e-25
CP021912.1\|AWW75831.1\|3277804_3280477_+\|aconitate-hydratase-1	gnl\|CDD\|236445	PRK09277, PRK09277, aconitate hydratase AcnA.	0
CP021912.1\|AWW75841.1\|3289312_3290182_+\|epimerase	gnl\|CDD\|223528	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	3.29552e-32
CP021912.1\|AWW75826.1\|3272006_3272930_+\|histone-deacetylase	gnl\|CDD\|212519	cd09993, HDAC_classIV, Histone deacetylase class IV also known as histone deacetylase 11. Class IV histone deacetylases (HDAC11; EC 3.5.1.98) are predicted Zn-dependent enzymes. This class includes animal HDAC11, plant HDA2 and related bacterial deacetylases. Enzymes in this subfamily participate in regulation of a number of different processes through protein modification (deacetylation). They catalyze hydrolysis of N(6)-acetyl-lysine of histones (or other proteins) to yield a deacetylated proteins. Histone deacetylases often act as members of large multi-protein complexes such as mSin3A or SMRT/N-CoR. Human HDAC11 does not associate with them but can interact with HDAC6 in vivo. It has been suggested that HDAC11 and HDAC6 may use non-histone proteins as their substrates and play a role other than to directly modulate chromatin structure. In normal tissues, expression of HDAC11 is limited to kidney, heart, brain, skeletal muscle and testis, suggesting that its function might be tissue-specific. In mammals, HDAC11 proteins are known to be involved in progression of various tumors. HDAC11 plays an essential role in regulating OX40 ligand (OX40L) expression in Hodgkin lymphoma (HL); selective inhibition of HDAC11 expression significantly up-regulates OX40L and induces apoptosis in HL cell lines. Thus, inhibition of HDAC11 could be a therapeutic drug option for antitumor immune response in HL patients.	1.28209e-129
CP021912.1\|AWW75823.1\|3269790_3270939_+\|4-hydroxy-3-methylbut-2-en-1-yl-diphosphate-synthase	gnl\|CDD\|234737	PRK00366, ispG, flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase.	0
CP021912.1\|AWW75824.1\|3270945_3271449_+\|protein-disulfide-isomerase	gnl\|CDD\|379399	pfam13899, Thioredoxin_7, Thioredoxin-like. Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond.	1.70439e-10
CP021912.1\|AWW75829.1\|3275179_3276574_-\|L,D-transpeptidase	gnl\|CDD\|225536	COG2989, COG2989, Uncharacterized protein conserved in bacteria [Function unknown].	2.72442e-58
CP021912.1\|AWW75842.1\|3290368_3290935_+\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	5.27902e-126
CP021912.1\|AWW75838.1\|3285906_3286992_+\|chorismate-synthase	gnl\|CDD\|235438	PRK05382, PRK05382, chorismate synthase; Validated.	0
CP021912.1\|AWW75833.1\|3281566_3282436_+\|hypothetical-protein	gnl\|CDD\|236766	PRK10811, rne, ribonuclease E; Reviewed.	6.43027e-05
CP021912.1\|AWW75827.1\|3272971_3274420_+\|hypothetical-protein	gnl\|CDD\|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	6.15029e-07
CP021912.1\|AWW75834.1\|3283037_3284078_-\|Holliday-junction-branch-migration-DNA-helicase-RuvB	gnl\|CDD\|234619	PRK00080, ruvB, Holliday junction branch migration DNA helicase RuvB.	0
CP021912.1\|AWW75825.1\|3271464_3272007_+\|manganese-efflux-pump-MntP	gnl\|CDD\|308338	pfam02659, Mntp, Putative manganese efflux pump. MntP is a family of bacterial proteins with a signal peptide and four transmembrane domains. It is a putative manganese efflux pump, since deletion of the gene leads to profound manganese sensitivity and elevated intracellular manganese levels in bacteria. Manganese is a highly important trace nutrient for organisms from bacteria to humans, and acts as an important element in the defense against oxidative stress and as an enzyme cofactor.	1.44007e-29
CP021912.1\|AWW75840.1\|3288170_3289316_+\|fatty-acid-desaturase	gnl\|CDD\|239584	cd03507, Delta12-FADS-like, The Delta12 Fatty Acid Desaturase (Delta12-FADS)-like CD includes the integral-membrane enzymes, delta-12 acyl-lipid desaturases, oleate 12-hydroxylases, omega3 and omega6 fatty acid desaturases, and other related proteins, found in a wide range of organisms including higher plants, green algae, diatoms, nematodes, fungi, and bacteria. The expression of these proteins appears to be temperature dependent: decreases in temperature result in increased levels of fatty acid desaturation within membrane lipids subsequently altering cell membrane fluidity. An important enzyme for the production of polyunsaturates in plants is the oleate delta-12 desaturase (Arabidopsis FAD2) of the endoplasmic reticulum. This enzyme accepts l-acyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate and requires NADH:cytochrome b oxidoreductase, cytochrome b, and oxygen for activity. FAD2 converts oleate(18:1) to linoleate (18:2) and is closely related to oleate 12-hydroxylase which catalyzes the hydroxylation of oleate to ricinoleate. Plastid-bound desaturases (Arabidopsis delta-12 desaturase (FAD6), omega-3 desaturase (FAD8), omega-6 desaturase (FAD6)), as well as, the cyanobacterial thylakoid-bound FADSs require oxygen, ferredoxin, and ferredoxin oxidoreductase for activity. As in higher plants, the cyanobacteria delta-12 (DesA) and omega-3 (DesB) FADSs desaturate oleate (18:1) to linoleate (18:2) and linoleate (18:2) to linolenate (18:3), respectively. Omega-3 (DesB/FAD8) and omega-6 (DesD/FAD6) desaturases catalyze reactions that introduce a double bond between carbons three and four, and carbons six and seven, respectively, from the methyl end of fatty acids. As with other members of this superfamily, this domain family has extensive hydrophobic regions that would be capable of spanning the membrane bilayer at least twice. Comparison of sequences also reveals the existence of three regions of conserved histidine cluster motifs that contain eight histidine residues: HXXXH, HXX(X)HH, and HXXHH. These histidine residues are reported to be catalytically essential and proposed to be the ligands for the iron atoms contained within the homologue, stearoyl CoA desaturase. Mutation of any one of four of these histidines in the Synechocystis delta-12 acyl-lipid desaturase resulted in complete inactivity.	1.91406e-63

>CP021912.1|AWW75832.1|3280486_3280960_+|rhodanese
MIESRLFLSSLTVLALAACAPSKDKDEGRDSAPPLGYELAMAKEAIPGVAATAAVVDLSVDELRARLDSGGTRLIDVRTSEEVARGTIPGAEHVALDQFDPASLDLSDGREVVLYCRSGRRSATAGEKLAAHTGKPAAHLGGGILAWQEAGEAIETP
>CP021912.1|AWW75831.1|3277804_3280477_+|aconitate-hydratase-1
MTATGKDTLSTRSTLDVNGKSYAYYSLAKAADQLGDVSKLPTSMKVLLENLLRFEDEGFTVGRDHIQAIVDWQNDPKTGNEIQYRPARVLLQDFTGVPCVVDLAAMRDAIKALGGDTQKINPQVPVDLVIDHSVMVDEFGHPKAMEANMALEYERNAERYDFLKWGSKSFKNFTAVPPGTGICHQVNLEYIGRGVWSSEDADGNMVAYPDTCVGTDSHTTMINGLGVLGWGVGGIEAEAAMLGQPISMLIPEVVGFKLTGKMAEGVTATDLVLTCVQMLREVGVVGRFVEFYGEGVANLTLADRATIANMAPEYGATCGFFGIDDKTIEYLRLTGRSEEEIALVEAYSKEQGMWFDPANEPVFTKTLELDVSSVVPSLAGPKRPQDRVILPEVDELFNGELKTVYNKAGAERTPVDGKDHDIGDGDVVIAAITSCTNTSNPDVLIAAGLVAKKANERGMKPKPWVKTSLAPGSQVVTDYLEKSGLQDDLNAIGFDLVGYGCTTCIGNSGPLAPPISAAINGNDIVAASVLSGNRNFEGRVSPDVRANFLASPPLVVAYALKGTVTEDITTTPIGQDQDGNDVMLADLWPTNAEVAEHRAANIDRSMFVNRYANVYDGDEHWQAITVEPSDTYQWRAGSTYVANPPYFEGMDMTPAPITDIVDAKPLAILGDSVTTDHISPAGAIKEDSPAGEYLKSNQVQKKDFNSYGSRRGNHDVMMRGTFANIRIRNEMVPGVEGGYTTYNGEQMPIYDAAMKHKADGTQLIVVGGKEYGTGSSRDWAAKGTILLGVRAVIVESFERIHRSNLVGMGVLPLQFEEGTTRETLELDSDCTFSIKGLADLTPGQTVEIEATRGDGTTFTFNALCRIDTANEMEYYRNGGILQYVLRKLAA
>CP021912.1|AWW75830.1|3276758_3277655_+|EamA-family-transporter
MSEPSPLSRLIPFAIAALGVGCLSTMDAFMKEAALATGTYTATILRSLIGAAIIAPFWLWQRTGWPKWATLKLHIERGIISAFMALTFFYALTKLPLAESIAISFIAPLIALYLARILLGEVIQPKAIFASLLGFAGTIVIISGKIGQDSFDNDAALGLASLLVSALLYSYNFIVIRRQSQVAGPVEIATFHSGVGGAVLLLGTPFFATPIASEAILPLVFAGVLTVCGAMAFAWAYARAEAQALVPIEYSGFLWASVLGWLFFREAVTIPTMAGTALIVTGCWLATRKGRARQPAPA
>CP021912.1|AWW75829.1|3275179_3276574_-|L,D-transpeptidase
MQNWVSSLAAGVAGAALLASGALAQDEAAPAPAQSAEGQQQTETPADASFDEAFPRMVSEPLIQGDLAPPGPMVQEWEVSQVNALIDVIEGIGAEGLEPAEYNLTQLKALVGQGRSETLDATASESFVWLVEDLRDGRTPMSARVQWFVVDPDRDTYRTGDLLTEALETGDVAGVLAKLNPTHPDYARLREELAVTPADETGKRKLIRANMDRWRWLARDLGTQYLITNVPEFQLRLTVRDRIISTYRTVVGKPGRTATPQLAEMVEGVVFNPTWTVPQSIVKGEGLGERVLGNPGWARANGYTATRGSNGWITVVQQPGPGNSLGRMKLEMPNPHAIFFHDTPSRHLFANANRALSHGCIRTERALELAITMAILGKGATRDEAVEIATSGKYTKVMIEKQLPAYITYFTMGVDIEGELRTFDDIYGRDAPVLASLDKPREANRSGESDDEVIVIENDPRGEA
>CP021912.1|AWW75828.1|3274469_3275183_+|twin-arginine-translocation-pathway-signal
MNRRDLIKSGLVAGAAMALPGLPAKLAAQPRAGNQRDRALFDIAKRELDRAGDAIWRRDIVGIADFGVHSAKPRFYFVNLDREEVSVAHCSHGAGSDPEHDGWLNSYSNVEGSNATSKGAYVTWEWYQGRYGTSVRLGGLDPTNDAALRRYIVMHRADYAEPSHVDRWGRLGRSNGCFAFGQDDFRYALMNLSGGRLLYADSIGLQADGAMLSREQQLAVLQPAKPNLTQRYNPGVY
>CP021912.1|AWW75827.1|3272971_3274420_+|hypothetical-protein
MSSQATDYLIIGAGAVGLAFADTLIDEDPDCHITIIDKHVAPGGHWNDAYSFVTLHQPSATYGVNSMELCPDRVDTHGHNAGMYPLAKHSEILAYYSKLMSERLIPSGRVAYHSLTEYIGKDASTHTARHILSGEEIAFDVRRKLVDATWFKTSVPATHKPAFDIAEGTRFAIPGDLPGLWKDTQNLPQHYVVIGGGKTAMDTAVWLLEAGVSPDRIDWVRPRDSWMFNRKLLQPAKHHIEDLIRFQVDLAECAASSETGDEMFAKLGERGTMLRIDPEVTPKMFHYAVISEAEIALLRQITNVHRGRHVTALEPQAMVLGDDRIELPEDTIFINCTATAVPFEQRDNQRPFFEGDLVTLQLAQTPFVPYSASLAAFLEANFETDEKRNALCPPAPLTDATDTYPYAVMANLMSTAILSNNEKTNAFNAKSRLHPTGPAVAEMIAKGDPRLAELSKVAPAIQANMPGIIQLGMKAKALHEAS
>CP021912.1|AWW75826.1|3272006_3272930_+|histone-deacetylase
MLHVVHHADYMVPRPASGSFNFDKYYLVMEELRGSGAPITEHAPDPCPREWLEAVHDPAYVDEVFNAQVPRAKERRIGFPVTTRIRDRVRHTNGGTWLAAQLAMQHGYAANSAAGSHHALGDTGAGYCVFNDLAVATNRLIAQGDAARVLIVDLDVHQGDGTASLLAGREDVFTLSVHAEKNFPVRKARSTLDIGLPDGTDDDGYMETLDRHLPGIIDSFAPDFVFYQAGVDPHVEDKLGRLALTDEGLMQRDRFVVREARRRGLAIASALGGGYGDDQRVVAARHARSMLAMADENTQVTLAPHRC
>CP021912.1|AWW75825.1|3271464_3272007_+|manganese-efflux-pump-MntP
MIEALLLAVALAMDAFAVALAQGARFRPDIGPALRIALVFGFAQGAMAALGWALGEAALVWAGGLFHWIAFALLVIIGGLMLRGGGEDEARPLMGVAALLGAALATSIDALAAGVALPEIALDPPITVALIAGATLALSLAAVQLGKIAGERFGRPAEICGGLILIALGCKIALEHTAAI
>CP021912.1|AWW75824.1|3270945_3271449_+|protein-disulfide-isomerase
MIKPILAGLAAALLVTGCATVADTGGHAAHDYPEARSYAVSQNAMGDVDAALARALDNDKRVLLVMGANWCHDSRALAGWLTSERIGPLVDEQYELVFVNIGMPQQGDGHNLHIAQRFGLDDLPGTPNVLVLTADGTLVNADTATTWRNAASRSEDAIYDELASLAG
>CP021912.1|AWW75823.1|3269790_3270939_+|4-hydroxy-3-methylbut-2-en-1-yl-diphosphate-synthase
MNAIRPWRTVERRECRQIMVGNVPVGGDAPITVQTMTNTPTEDAAATIDQIRRCEDVGCDIIRVSCPTEEATAAMPLITRAANIPVVADIHFHYKRALEAADAGAACLRINPGNIGGSDRVAEVVRAAKANGCAIRIGVNAGSLEKDLLEKYGEPCPEALIESALDHIKLLQDHDFHEFKVAVKASDVFLAVAAYHGLADAVDCPLHLGITEAGGLIGGTVKSSIGMGSLLWAGIGDTIRVSLSAEPEEEVKVGYEMLKALGIRTRGVRVVSCPSCSRQGFDVIRTVETLEKRLEHIKTPMSLSVLGCVVNGPGEARETDIGLTGGGSGKHMVYLSGVKAHTIEDEDMLDHIVRLVEEKAARIEAGEEVAFDPHATEVQADE
>CP021912.1|AWW75833.1|3281566_3282436_+|hypothetical-protein
MLPELPPLVAPPELELDEDELEEDELEELDEPEPPDEPLLDPLSPPEDELDEEDDELLDEELLDDELDDTLPEELLTLPEELETLPEELDTLPEELDTLPDELETLPDEVETAPVELDTPPVEVETAPVDVETPPVEVDTPPVLDETAPVDELIEPVDEVEVTLPDVVVEDIVPDDVEASTSMSMLMSPDEPPPDVLEPPLEVELEPPLVEVLKLPPLVVELKSPPEVVVVVETPRSPEDDPPPPKKPPMKPPPKPPPKPPPKPPPNTGPPKPPPPPVMGGSGGSGAGA
>CP021912.1|AWW75834.1|3283037_3284078_-|Holliday-junction-branch-migration-DNA-helicase-RuvB
MTEAAPIHSGENQPGDPDTALRPKRLAEFIGQEGAKDNLRVFIDSARARGEAMDHTLFHGPPGLGKTTLAQIVAGELGVGFRATSGPVIAKAGDLAALLTNLEPHDVLFIDEIHRLNPVVEEVLYPAMEDRALDIIIGEGPSARSVRIDLPPFTLVGATTRQGLLTTPLRDRFGIPVRLQFYTHEELDQVVNRAARLLGLNMDPAGAREIARRSRGTPRVAGRLLRRVRDFAQVAGEATVTRAMADDALTRLEIDRLGLDAMDRRYLTMIAETYKGGPVGVAALSAGLAEQRDTVEEVIEPYLIQLGLIARTERGRMLNDAGWEHLGVAKPVSRSGSQPSMFDESD
>CP021912.1|AWW75835.1|3284074_3284464_-|hypothetical-protein
MRTTIFVSLFVLTACGVAPNEDAPAESMEANDPSLVTREGFAAAGLAWPLTVESGRLGCTQMARWVEVNGTRYGLNGLASAERGYAELEDIWAVDEDMMAEFADAGAVDIPTVRINIGDMSSQADAFCE
>CP021912.1|AWW75836.1|3284477_3284999_-|hypothetical-protein
MKHALALALATLIASPLSAQQASREGFATGPVFDEFGPHAPVPTAEPIPSFSRFEIAFDVATAADDGARNRGFESAARFMNMHVAAGVPEDRIKLVVVVHGRAAGDLVSGEGNVSEAMIQAMLDRGVRFILCGQSAAARGVNPDELIEGVEMQLSAMTAHALLQQQGYTVNPF
>CP021912.1|AWW75837.1|3284995_3285604_-|Holliday-junction-branch-migration-protein-RuvA
MIAKLNGRLDETGEDWAIVDVSGVGYLVHCSARTLAALGEVGEACTVHTDLQVSENDMRLLGFAESAERDWFRLLTQVQGVGSKVGLAILSALSTGELRDACAAGDAAIVARANGVGPKLAGRIVNELKDKAGALPGGGLAGVAVGAANPAGSASADAVSALENLGFKPAIAAQAVARATAELGEDAPEGDLIRVALKKAAS
>CP021912.1|AWW75838.1|3285906_3286992_+|chorismate-synthase
MSFNTFGRSLRFTTWGESHGPGLGVVLDGCPPGIPLRETDIQPFMDARKPGQNKFTTQRKEADAVRILSGVFTTSEGDQVTTGTPIHLMIENTDQRSKDYSEIAQSYRPGHADYTYDAKYGIRDYRGGGRSSARETAARVAAGAVARLIIPEVTITGFVCELGGDRIERDAINYDIIDQNPFFCPDSWAAKRWEELVDLARKNGSSLGAVVECVAEGVPAGWGAPVYAKLDSELAAAMMSINATKGVEIGDGFEAARLTGEQNADPMRPGKDGKPIFASNHAGGTAGGISTGQPVVCRVAFKPTSSILTPVDSITSEGEATKVRTKGRHDPCVGIRGTPVVEAMMALVLADAKLMHRAQVG
>CP021912.1|AWW75839.1|3287040_3288069_-|hypothetical-protein
MPAADAVFDMDELRRRAWETTVPAGGDYQAQTDERLDWLDKGTPEDWHRFAIGFNWSDNIEPLYWIARQEQCEMATALHIFWHACPEWELMKLAEGEPIYDRDEAAMVEYIAKRIAAKGYKRRKIAWDANSLHKRDYDEMRAFVARIDNPPWKPHRDLLRSIWGKEVMDGPEAWEERPENVRTGFWLDLPKSDIVTWVMREARDEMRPTFFNLFAIGGLLAATVEFLNDPARWWLHLIGCIVMIGWWSWGISASTSTVRSLMRSELKIVPTRQMALTYLALVAIGALWLQGYFALSAIFAEAKDTSFEARAIKAAVCVVWIAPFWFGLRWAAEQYTYRHLFR
>CP021912.1|AWW75840.1|3288170_3289316_+|fatty-acid-desaturase
MTNAHVDAGVLHGEGQGHAASSGCAGENLHAMARSDHDQNPSQDRIDTDNPRAIARTLARFRTPRASRSGWELAVTFLPFAATFAAMLFAVEAGYYIALLLTPVAGLFLLRLFIIQHDCGHEAFFRKKGSNNWVGRGIGVFTLTPYDCWRRSHALHHASTGNLDARGFGDVDTLTVNEYMQKGRIARGFYRLYRHPVVLLGLGPAYLFLLRHRLPVGLMKAGAIYWVSALATNAVTAAILVGLAFAFGIATTALVFVPVLVTAASIGVWLFYVQHQFDEVAWDNREDWEFHAHALAGSSYLHLPGWLHWFTGNIGIHHVHHLMSRIPFYRLPDVLKEYPELAEVNRITLKQTPRLFLLALWDEERKRLVSFREAKRITANM
>CP021912.1|AWW75841.1|3289312_3290182_+|epimerase
MKRVVLTGSSGRIGRAIFGALASEYRVAGIDRNTFSTTHIVGDCAEPDVIAPALEGADAVIHTAGPHAPHVGILSDGEFERVNVEGTRTLFNLAAKSGVKRFVYTSTTALYGNAIVPGECTWVTDETQPAPKSIYHRTNLAAEAFLEEAASHAMPVRVMRMSRCFPEPAPTMALLRLHRGVDARGVGTCHRLALTHEGAPFERFIISGATPFGKEDCNDLAASAADVIRERVPDLARAFDARGWSLPDSVDRVYDATAAREALGWKQRWGWEEVLAQWDRDSIEVLAPE
>CP021912.1|AWW75842.1|3290368_3290935_+|peroxiredoxin
MGIIGSTIKPFTATAFKAGEDFYDVSQADIEGKWAVFFFYPADFTFVCPTELEDLGEKYDMLQSMGVEVFAVSTDTHFSHKAWHDTSDKIGKLKFPFLGDQNHVLANNFGVLREGVGLADRATFVVDPDGVIQIMEITCEGVGRNANELTRKIKAAQYVRNNPGQVCPAAWEEGSETLAPSLDLVGKI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

928132 : 935896

Escherichia_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWW73683.1\|928132_928828_-	hypothetical protein	A0A0P0YLT6	Yellowstone_lake_mimivirus	4.7e-15	45.3
AWW73684.1\|928938_930501_-	glycosyl transferase	NA	NA	NA	NA
AWW73685.1\|930545_931598_-	dTDP-glucose 4,6-dehydratase	A0A1D8EQC0	Escherichia_phage	7.0e-79	45.0
AWW73686.1\|931590_932439_-	dTDP-4-dehydrorhamnose reductase	I7HXC9	Enterobacteria_phage	1.0e-32	39.0
AWW73687.1\|932435_932981_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	5.5e-51	54.5
AWW73688.1\|932992_933886_-	glucose-1-phosphate thymidylyltransferase	K7QKA7	Escherichia_phage	2.1e-92	57.9
AWW73689.1\|934016_934829_-	mannose-6-phosphate isomerase	NA	NA	NA	NA
AWW73690.1\|934834_935896_-	mannose-1-phosphate guanylyltransferase	A0A1V0SH58	Hokovirus	1.0e-24	26.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage