CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP030104	Flagellimonas sp. HME9304 chromosome, complete genome	2 crisprs	WYL,csa3,DEDDh,RT,cas3	4	4	0	0

1. CP030104

CRISPR-Cas detection and classification

Crispr_ID: CP030104_3

• CRISPR_ID: CP030104_3
• CRISPR_location: 972838-972938
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP030104_3

Consensus_repeat	Method
CTGAACCAACTGAGCTACGCGCCC	CRISPRCasFinder

spacers of CP030104_3

>3.1|972862|53|CP030104|CRISPRCasFinder
GAAATCTTTATTTTTCGGGAACCTGAACCCTCCCGATGCAAAATCGGGATGCC

CRISPR arrays and Neighbor proteins around CP030104_3

CRISPR arrays

The CRISPR arrays of CP030104_3

>merge|CP030104|3|972838-972938|CRISPRCasFinder
CTGAACCAACTGAGCTACGCGCCCGAAATCTTTATTTTTCGGGAACCTGAACCCTCCCGATGCAAAATCGGGATGCCCTGAACCAACTGAGCTAAGCGCCC

>CP030104|3|3|972838-972938|CRISPRCasFinder
CTGAACCAACTGAGCTACGCGCCC	GAAATCTTTATTTTTCGGGAACCTGAACCCTCCCGATGCAAAATCGGGATGCC
CTGAACCAACTGAGCTAAGCGCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP030104.1|AWX43887.1|973011_974223_-|Dihydrofolate-synthase	unknown	unknown	gnl|CDD|223362
CP030104.1|AWX43892.1|977877_979017_+|Acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
CP030104.1|AWX43885.1|971124_972003_+|Molybdate-transporting-ATPase	unknown	unknown	gnl|CDD|224043
CP030104.1|AWX43890.1|975499_976192_-|Biopolymer-transport-protein-ExbB	unknown	unknown	gnl|CDD|376576
CP030104.1|AWX43879.1|963695_964400_-|hypothetical-protein	unknown	unknown	unknown
CP030104.1|AWX43893.1|979342_983848_+|Glutamate-synthase-(ferredoxin)	unknown	unknown	gnl|CDD|236968
CP030104.1|AWX43894.1|983856_985323_+|Glutamate-synthase-(NADPH)	unknown	unknown	gnl|CDD|237213
CP030104.1|AWX43883.1|970055_970457_+|hypothetical-protein	unknown	unknown	gnl|CDD|226113
CP030104.1|AWX43877.1|962720_963095_+|DCC-family-protein-chloroplastic	unknown	unknown	gnl|CDD|367833
CP030104.1|AWX43882.1|969289_970063_+|Molybdate-binding-periplasmic-protein	unknown	unknown	gnl|CDD|270257
CP030104.1|AWX43884.1|970453_971128_+|Putative-molybdenum-transport-system-permease-protein-YvgM	unknown	unknown	gnl|CDD|226629
CP030104.1|AWX43880.1|964472_965888_-|hypothetical-protein	unknown	unknown	gnl|CDD|185760
CP030104.1|AWX43878.1|963206_963617_-|6-pyruvoyltetrahydropterin-synthase	unknown	unknown	gnl|CDD|238264
CP030104.1|AWX43896.1|993103_994585_-|hypothetical-protein	unknown	unknown	gnl|CDD|185760
CP030104.1|AWX43889.1|975104_975491_-|hypothetical-protein	unknown	unknown	gnl|CDD|376792
CP030104.1|AWX43881.1|965899_968920_-|TonB-dependent-receptor-SusC	unknown	unknown	gnl|CDD|274948
CP030104.1|AWX43895.1|990975_992961_-|hypothetical-protein	unknown	unknown	gnl|CDD|379481
CP030104.1|AWX43891.1|976249_977635_-|hypothetical-protein	unknown	unknown	gnl|CDD|215071
CP030104.1|AWX43886.1|972159_972546_-|hypothetical-protein	unknown	unknown	gnl|CDD|198396
CP030104.1|AWX43888.1|974226_975105_-|hypothetical-protein	unknown	unknown	gnl|CDD|274303

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP030104.1|AWX43887.1|973011_974223_-|Dihydrofolate-synthase	gnl|CDD|223362	COG0285, FolC, Folylpolyglutamate synthase [Coenzyme metabolism].	1.53997e-117
CP030104.1|AWX43892.1|977877_979017_+|Acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	0
CP030104.1|AWX43885.1|971124_972003_+|Molybdate-transporting-ATPase	gnl|CDD|224043	COG1118, CysA, ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism].	1.17437e-84
CP030104.1|AWX43890.1|975499_976192_-|Biopolymer-transport-protein-ExbB	gnl|CDD|376576	pfam01618, MotA_ExbB, MotA/TolQ/ExbB proton channel family. This family groups together integral membrane proteins that appear to be involved translocation of proteins across a membrane. These proteins are probably proton channels. MotA is an essential component of the flageller motor that uses a proton gradient to generate rotational motion in the flageller. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane.	2.65149e-31
CP030104.1|AWX43893.1|979342_983848_+|Glutamate-synthase-(ferredoxin)	gnl|CDD|236968	PRK11750, gltB, glutamate synthase subunit alpha; Provisional.	0
CP030104.1|AWX43894.1|983856_985323_+|Glutamate-synthase-(NADPH)	gnl|CDD|237213	PRK12810, gltD, glutamate synthase subunit beta; Reviewed.	0
CP030104.1|AWX43883.1|970055_970457_+|hypothetical-protein	gnl|CDD|226113	COG3585, MopI, Molybdopterin-binding protein [Coenzyme metabolism].	1.9857e-08
CP030104.1|AWX43877.1|962720_963095_+|DCC-family-protein-chloroplastic	gnl|CDD|367833	pfam04134, DUF393, Protein of unknown function, DUF393. Members of this family have two highly conserved cysteine residues near their N-terminus. The function of these proteins is unknown.	8.30403e-31
CP030104.1|AWX43882.1|969289_970063_+|Molybdate-binding-periplasmic-protein	gnl|CDD|270257	cd13539, PBP2_AvModA, Substrate binding domain of ModA/WtpA from Azotobacter vinelandii and its closest homologs;the type 2 periplasmic binding protein fold. This subfamily contains domains found in ModA proteins that serve as initial receptors in the ABC transport of molybdate in eubacteria and archaea. Bacteria and archaea import molybdenum and tungsten from the environment in the form of the oxyanions molybdate (MoO(4) (2-)) and tungstate (WO(4) (2-)). After binding molybdate with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. In contrast to the structure of the two ModA homologs from Escherichia coli and Azotobacter vinelandii, where the oxygen atoms are tetrahedrally arranged around the metal center, the structure of Pyrococcus furiosus ModA/WtpA (PfModA) has shown that a binding site for molybdate and tungstate is where the central metal atom is in a hexacoordinate configuration. This octahedral geometry was rather unexpected. The ModA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.48247e-100
CP030104.1|AWX43884.1|970453_971128_+|Putative-molybdenum-transport-system-permease-protein-YvgM	gnl|CDD|226629	COG4149, ModC, ABC-type molybdate transport system, permease component [Inorganic ion transport and metabolism].	2.53331e-81
CP030104.1|AWX43880.1|964472_965888_-|hypothetical-protein	gnl|CDD|185760	cd08977, SusD, starch binding outer membrane protein SusD. SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.	2.24584e-40
CP030104.1|AWX43878.1|963206_963617_-|6-pyruvoyltetrahydropterin-synthase	gnl|CDD|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	4.4715e-40
CP030104.1|AWX43896.1|993103_994585_-|hypothetical-protein	gnl|CDD|185760	cd08977, SusD, starch binding outer membrane protein SusD. SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.	2.63741e-19
CP030104.1|AWX43889.1|975104_975491_-|hypothetical-protein	gnl|CDD|376792	pfam02472, ExbD, Biopolymer transport protein ExbD/TolR. This group of proteins are membrane bound transport proteins essential for ferric ion uptake in bacteria. The Pfam family consists of ExbD, and TolR which are involved in TonB-dependent transport of various receptor bound substrates including colicins.	3.69218e-21
CP030104.1|AWX43881.1|965899_968920_-|TonB-dependent-receptor-SusC	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
CP030104.1|AWX43895.1|990975_992961_-|hypothetical-protein	gnl|CDD|379481	pfam14121, Porin_10, Putative porin. This family of membrane bet-barrel proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 655 and 722 amino acids in length. SRI_1264 is identified by Gene3D as a membrane bound beta-barrel. These sequences are putative porins.	0
CP030104.1|AWX43891.1|976249_977635_-|hypothetical-protein	gnl|CDD|215071	PLN00137, PLN00137, NHAD transporter family protein; Provisional.	1.34591e-118
CP030104.1|AWX43886.1|972159_972546_-|hypothetical-protein	gnl|CDD|198396	cd10449, GIY-YIG_SLX1_like, Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its homologs. Structure-specific endonuclease subunit SLX1 is a highly conserved protein from yeast to human, with an N-terminal GIY-YIG endonuclease domain and a C-terminal PHD-type zinc finger postulated to mediate protein-protein or protein-DNA interaction. SLX1 forms active heterodimeric complexes with its SLX4 partner, which has additional roles in the DNA damage response that are distinct from the function of the heterodimeric SLX1-SLX4 nuclease. In yeast, the SLX1-SLX4 complex functions as a 5' flap endonuclease that maintains ribosomal DNA copy number, where SLX1 and SLX4 are shown to be catalytic and regulatory subunits, respectively. This endonuclease introduces single-strand cuts in duplex DNA on the 3' side of junctions with single-strand DNA. In addition to 5' flap endonuclease activity, human SLX1-SLX4 complex has been identified as a Holliday junction resolvase that promotes symmetrical cleavage of static and migrating Holliday junctions. SLX1 also associates with MUS81, EME1, C20orf94, PLK1, and ERCC1. Some eukaryotic SLX1 homologs lack the zinc finger domain, but possess intrinsically unstructured extensions of unknown function. These unstructured segments might be involved in interactions with other proteins.	4.32355e-27
CP030104.1|AWX43888.1|974226_975105_-|hypothetical-protein	gnl|CDD|274303	TIGR02794, Protein_TolA, TolA protein. TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	6.6284e-07

Protein sequences

>CP030104.1|AWX43886.1|972159_972546_-|hypothetical-protein
MEEPQDDRKINREVVFQDIPILHREGQGFESLRAHKGFPCMGGLFLYTMFYTYILYSRVLDKFYIGYTENLEARLIKHNQFHKGFTGRAKDWEIKFVEGFVSKTEAMSREKQIKRWKSRKMIEKLIGK
>CP030104.1|AWX43885.1|971124_972003_+|Molybdate-transporting-ATPase
MIELDIDKKLHAADGEMNLGLHFSIEKGKLITLYGESGAGKTSTLRLLSGLMKPDKGKIIVKGKTWFDSDKKTNLPPQKRKIGYVFQDYALFPNMTVYKNLEFTLSKGQDKKKVSDLIEIMELGELQYRKPETLSGGQKQRVALARALVEQPEILLLDEPLAALDIKIRLKLQDYILKVHREFNLTTLLISHDIGEINKLSDHVIFLEKGKVVRQGNPDDLFINRNISGKFKFTGEILKIEKQEIVNIATVLIQSSVVKVIVLDSEIQQLRVGDKVMVATKAFNPILYKVEI
>CP030104.1|AWX43884.1|970453_971128_+|Putative-molybdenum-transport-system-permease-protein-YvgM
MIDWNPLLLTFELAIATTVILLILSIPLAYWLSNTKTRFKAIVETLVSMPLVLPPTVIGFYFLMAFSPNNFFGEWINEWLGITLVFSFPGLVIASIIYSLPFMVHPIQSGLSNLPKSIQEAAYVMGKSKLTTLFRIQLPNIKTSLLTGIVLSFAHTVGEFGVVLMIGGNIPGRTKVASIAIYDEVEALNYEAANLYSIILFAITFCILLAVYLKTGKHLNKLGR
>CP030104.1|AWX43883.1|970055_970457_+|hypothetical-protein
MNSLNGHITHIKVNGSLSLVTIGLGKNATIQSIVIETPKTAPYLQTGKPVKVFFKETEVIIGNNENHAITLQNRILGTIKEIEKGTLLSKVSIDSDAGKLISVISTDSCEYLNLKKGDMVFAMVKLNEIMLSE
>CP030104.1|AWX43882.1|969289_970063_+|Molybdate-binding-periplasmic-protein
MRLSNAITYSFIGIFLYLFSSCDIQNTGETVTIAAAANMRYPLKELTKAFTKETGIKCNLVISSSGTLTAQIKQGAPYDIFVSADTTYPEEIWESGLTEKPPKIYAYGKLVLWTMKSGIKPAISMLKNDSISHIAIANPKIAPYGRAAISVLNHYKLLDEVEDKLVYGESISQTNQFILSTSAQLGFTAMSVVLAPELKKKGTWVELENNLYEPIAQSAVQIIHKEVNKESAESFYDFLFSKKAREILENFGYSVNE
>CP030104.1|AWX43881.1|965899_968920_-|TonB-dependent-receptor-SusC
MKVKKLFGTFFVMLFFMAFAHSQEKTITGTITDQGGMPLPGVNIVVEGTANGTQSDFDGNYTINASEGQVLVFTYLGQRTVQRTIGGQSTIDIQMEEDASQLEEVVVIGYGNQEERKIIQNVGIVKEEAIENLQVVSADQLLQGQSAGTQIVNASGVLGSAAVIRVRGVNSINSGSQPLIVIDGVPITDTEGNTLNRGGNTDINPLSYVNPNDIESLTVLKDAGATSIYGSRGANGVVLITTKKGRRNSKAQLTLDISTQFSESTDVPDILSADEFRQWKSEIATIQNGTLTTPEDLGLGAIGSGGTDWLEGVQRTGISQNYNLGVRGGGEKTSYFFGLDFQDAQGFVIGNDQQRTGARINIDSDVTNWLKAGMNLGITNNRLARVFVENEIDAPFTTAFLQSPVVRAFDDEGNFLQSGSFIPNIFARVALDDRELKTFRVIGNAFTEITPFEGLTWRSEFGMDWLSVEETTREAEFNTPGGLGQVVSVREERWLTNQTLNYTPNLGEDHSLNILLGLNYEETLRTRLNVSSTGFLTDGLRNLGSGSTPSVLNGDRFPSRLFGLFSRASYDYKGRYLVEGSLRRDGSSRFGVNNRFGYFWSVAAGWIISDESFMDDVSFVDYLSLRASIGTVGNDRLGTFPSLGLFNAGAFGDYNGESGVVPNQPPNPDLKWEESETLDIGLKSTFLNGRLNFNMSYFKKTTSDLLLNQVLPPQTGLRFISRNIGELENKGWEFDVSSINVLTEDFEWRTSFNITTIENTITQLNEDAATDAQGRKIIDGPIQRAIEGESLNNFFLIRYVGINSQTGDAEWLDVNGNITTTPNSGDRVVTGSPLPDFSGGMTNSFRFKDFDLSVLMNYSYGNDVVIDGLRFADGADAIGGIVNVRKQNLNIWRQPGDNAFLPSPNSSTFNPFNQRSTQQQLDASYLRVKNVTLGYNMPEQALEKLGGLFSGIRFYATATNLFTLKKDEMKGIDPEVTDDIDPRFQGESFFTAPQAKSYLIGARLTF
>CP030104.1|AWX43880.1|964472_965888_-|hypothetical-protein
MKIYKAIIIFLGIGIFFACEDRLDVVPEDSVEIETVFDTRGSINGAVVGIYSKNQSGDLNGNPQLISDFMADDVNFVGSFTSLQEIDQFETLATNTTIDNIWLDGYELIGAANNIIVNLPDIDLLDLSETEKAQFIGEAKFLRALTYFTLVNHFAQPFQVSGGSNLGVPLVLVPYAPEVDISEFQLERSTVNEVHALIEQDLLDAVASLPEDNGERAEAGAARGLLARLYLYREDWASAANLADQVISSGEYALAPDFDFYDDNPTSPENIFSVINTPTDGPQDESVPGSDEVYVNFYNPAPGGRGDAPFSQDLLDVFAGEPGDRRFAELSQAATDAGGNDTFFTTKYPDIVNNASDGMVLRMADMYLMRAEANLRGGTAIGDTPLNDVNTVRARAGLPALVTVDLDAILLERRKEFCFEGLRRMDLLRNDRNLRPAGGAESAPGADKVIFPIVDDELTNNPNITQNPGNF
>CP030104.1|AWX43879.1|963695_964400_-|hypothetical-protein
MKKIISYVTSILFLTSLQCQIVQNSAEGLNELDFFIHLNNTKYDNVEGSKYLFDEFRPAKINTIKTTHLVRFDVLEHIIELKKSESEIMGLSKNKTYSVTLLDGSNRIFLTKDFQDDNKQVKNGIFEQLHQNQKFILFKRSRIKFQEAKPIKSSYEKAVPAKFIPLEDVFYVSFRKNEEYSGLIKVPQKKKALKLFFGKYFAKIEKLVKEEKLKFDLEQDLIKIFNYYVEIRKE
>CP030104.1|AWX43878.1|963206_963617_-|6-pyruvoyltetrahydropterin-synthase
MIATICRKAHFNAAHRLHNPNWSDAKNIEVFGKCNSPNYHGHNFDLEVRIRGEVNPDTGFVMDLAVLGILIKEEVEDRFDHKNLNIDCPEFDEILPTTEYFVKIIYDILRPKLQKEQLLHITLHETQKNSAEYGDW
>CP030104.1|AWX43877.1|962720_963095_+|DCC-family-protein-chloroplastic
MEKSIIVFDGECNLCNGVVGWLLKFAPEDIFHFVPFQSPKGQELLKKHGFSTRQLETVILFDKNGKHTHSDGFLKIISKIPKWKLVAALLAFVPRIIRDTIYNMASKNRVKWFGKSRTCTVSFK
>CP030104.1|AWX43887.1|973011_974223_-|Dihydrofolate-synthase
MTYAATLDWMFQQLPMYQQKGSLAYKDKLDNVISFSKVLGNPEKKFKSIHVAGTNGKGSSSHMLASILQQAGYKVGLYTSPHLKDFRERIKINGEKVSEDYIQKFVDVNKNFLDQNELSFFEMTVGMAFNYFAKEKVDIAVIEVGLGGRLDSTNIITPEISLITNIGLDHVQILGNTLQKIALEKAGIIKKNIPVVISEKQPETEVIFRMIAAQKNTEIIFAEDIDIKNYETDLLGSYQKKNCKGVVAVINELKGFKIQDKHIEVGLKNTVTNTGLLGRWQVLGENPKIICDTAHNKEGLTLVMQQIEKLGFSQVHFVLGFVNDKSLDDVLPLFPKEAEYYFVRPNIPRGLSADELKAIASNFNLKGKVFKSVGKGLEAAVKNAKPRDLVYVGGSTFVVAEVV
>CP030104.1|AWX43888.1|974226_975105_-|hypothetical-protein
MSFLDTRHKKKSFTLTTLLLSVLLLLLFYIGLTYMDPPIENGIAVNFGTMDFGSGEVQPKEKVRSEPKTEQATPAEEIPEQFQEQETAENKPVEEVLTNESEETIKINQQKEAKRKADETAKKAKAEAERVALERKKAEEQKRKEQEAKKKSLDALIGGIGKSDGTTTGSEGDDNKAGGKGQPDGDPYATSYYGSPGSGSGTGGYGLNGRSLVNSGKVQQECNEEGRVVVRIVVDRNGKVIDATPGVKGTTNNAPCLLKPARETAQQHKWNLDSNAPSQQIGFVVVNFKLGQ
>CP030104.1|AWX43889.1|975104_975491_-|hypothetical-protein
MKLKGRNKVSPEFSMSSMTDIVFLLLVFFMLTSNAPNALDLLLPKAKGKSTNTQNVSVTINKNLEYFVNNERINEEYIEIELKKALEGQEKPTIILRAEESVAIKEAVNVMDIANRNSYKVILAVRPK
>CP030104.1|AWX43890.1|975499_976192_-|Biopolymer-transport-protein-ExbB
MIFFQDLEEGAEIGTSISEEKTLSVIDLIVNGGAGSIIIIAVLFVLLFTALYIYFERIFAIKAASKIDKNFMNQIRDHVMSGKLEAAKLLCAQTDSPVARLTEKGVSRIGKPLDDINTAIENAGTLEVYKLEKNVSVLATVAGAAPMIGFLGTVIGMILAFHEMASSGGQAEMGSLASGIYTAMTTTVAGLVVGIIAYIGYNHLVNRTDKVVHKMEANAVEFLDLLNEPI
>CP030104.1|AWX43891.1|976249_977635_-|hypothetical-protein
METVLIAVFVIGYLAITIEHTIKIDKLIPALAMMAILWALIAFGIDGFTTWFDSGKHALLDNFGLLDHEEKMHIMEESLLHHLGKTAEILVFLLGAMTIVEIIDYFDGFATIKSFIKTRSKRRILWIFAFLAFILSAIIDNLTATIVLISILQKIVRERNDRLWYAGLIIVAANAGGAWSPIGDVTTTMLWIGDKVTTSRLIGYLLIPSLVCMLVPTFIASFLPAFKGTIDSEETEPPKSKFGSTMLYLGLGAIVFVPIFKTVTHLPPYVGMMLSLAVVATFAEIYSNSKITISSVDMDSDAESHSGPVHSALTKIELPSILFFLGILMAVAALESLGLLFNFADNLKEGIGLMGTELPGTEVSDLVVIILGFGSAVIDNVPLVAASLGMFSEPQDNPLWHFIAYSAGTGGSMLIIGSAAGVVAMGMEKIDFFWYLKKIAWLAAIGFIAGAICFIVMRYFL
>CP030104.1|AWX43892.1|977877_979017_+|Acyl-CoA-dehydrogenase
MDFTLSEEQLMVQQAAKDFAQNELFPEVIERDDAQKFPTEQVKKMGELGFMGMMVNEKYGGSGLDTLSYVLVMEELSKIDASASVIVSVNNSLVCWGLETFGTEEQKQKYLTKLSTGEIIGAFCLSEPEAGSDATSQKTTALDKGDHYILNGTKNWITNGSTAEIYLVIAQTDVEKGHKGINALIVEKGMEGFEIGPKENKLGIRGSDTHSLIFNDVKVPKENRIGENGFGFKFAMKTLAGGRIGIAAQALGIAAGAYELSKKYAKERKAFGTEIANHQAIAFKLADMHTKIQAARHLVYQAACDKDNGADYTLSSAMAKLYASEVAMETTVEAVQIHGGNGFVKDYHVERLMRDAKITQIYEGTSEIQKIVISRSILK
>CP030104.1|AWX43893.1|979342_983848_+|Glutamate-synthase-(ferredoxin)
MRLEKQGLYLPEFEHDNCGAGFICSLKGRKSNDIIHKALEILDKLEHRGAVSSDGKTGDGAGILIDIPHDFFTEVCNFNLPKAGEYAVSNVFLPRKENQRDFCVSSLEKNIKKQGLVLLGWRDVPVNRSVPGRIASETEPYVKQVFIGRGNAIDDFQFNLKLFIARKITEHTIIKSKLSQHQFFYLPSLSTKIIIFKGLLVPNDISRYYEDLLDPRVVTRLALVHQRFSTNTFPTWDLAQPFRYMCHNGEINTLRGNVSRMRSREELLKSDWFGDDIKKILPVVLPRKSDSASMDMVVELLLMTGRSLPEVMMLLVPEAWEKNAEMSSSKRAFYEYNSCLMEPWDGPASIPFTDGNYIGAVLDRNGLRPSRYSVTKKGYVIMSSETGVVELEPEDIEFHGRLEPGKMFLVNMEEGRIINDEEIKESIAGKHPYKKWLKNNLVHLKDIPYNECPVFFGEFPLDTRRAAFGYTLEDINTIILPMAKNGKEPIGSMGSDTPIAVLSERPQLLYNYFKQLFAQVTNPPLDGIREELITDISLTLGSDQNIFDVTELHCRKLKIQNPVISKEDLDKIKNYDASPDYKVISISILYEIAKGHNGLEEALESVLKQASIAIDGGANIIILSDRMVSSEMAAIPALLACSFVNSGLRKLRKRSKLSIIIESAEPREVHHFALLFGFGASAINPYLVNEIIGEQIQENDITEYTFDEAIKNYNKAVGKGILKVMNKIGISTLNSYRGSQLFECIGINTKVVDKYFPNTPTRIQGIGLYEIEKEIAKRHKKAFKSQDLAANLNIEIGGEYRWRRDGEKHMFNPLSIAKLQKSVRNNEPDTYKEYSKLVNEQSKNLMTIRGLFEFSNYDPIPIEEVEPWTEIVKRFKTGAMSYGSISKEAHENLAIAMNRIGGKSNSGEGGEDSERFYKNQTGDWKNSAIKQVASGRFGVTSDYLTNAKEIQIKMAQGAKPGEGGQLPGPKVNPAIAKTRNSTPYVGLISPPPHHDIYSIEDLSQLIYDLKSANRDARINVKLVSEVGVGTVAAGVSKAKADVILISGFDGGTGASPLTSLKHAGLPWELGIAEAQQTLVMNDLRNRIVLECDGQLKTGRDVAVACLLGAEEFGFATAPLVASGCIMMRVCHLNTCPVGIATQKPELRKKFKGKPEHVVNYMYFVAEELRGIMAKLGFRTIDEMVGQVQKLDRKSAIEHYKAAGIDLSPILYQVDVPEETKFHNTDKQTHNIEKSIEFDIIAQAHPALFRKEKISLDFPIYNTDRAVGAIISNEISKIYGADGLPDNTLKLNFTGSAGQSFGAFATKGLTMVVNGNTNDYLGKGLSGAKLIIKVPYKSTLKPEDNIITGNVTLYGATSGEAYINGKAGERFCVRNSGAKAVVEGIGDHGCEYMTGGITVILGSVGRNFGAGMSGGIAYVFDTDRSFEKRCNAETLNFLPVEEDIDIRQLKELIENHYNATLSPLAQNILENWEKHLSKFVKVFPEEYRQALIRLEKEKLQTL
>CP030104.1|AWX43894.1|983856_985323_+|Glutamate-synthase-(NADPH)
MGKITGFMEFDRKVEAYVPVKKRIKNYNEFTVPLKEKELKNQGARCMDCGIPFCHSGCPLGNLIPDFNHAVYQGKWEKATKILHSTNNFPEFTGRLCPAPCEESCVLGINEDPVSIENIEKNIVETAFENGWIKPEPPINRTSKKVAVVGSGPAGLATAQQLNRAGHSVTVFERDEKIGGLLRYGIPDFKLEKSIIDRRLDIMTKEGIIFRTGVHIGFDIEAKELQKKFDAIVLCGGASIRRNLPIPGSELKGIVQAMDFLPQNNRKVDDIPYKGEEISAKEKKVIVIGGGDTGSDCIGTSIRQGAVSVINFEIMPKSTIHRPEGQPWPFWPMRLRTSSSHKEGAERVFSILTKKFIGDQDGNLTGLITSEVYWEKKPGERPVLKEVEGTEKEWECDLVLLALGFTGSETTIADQLRLKIDSRTNISASEKNYKTNISGIFVAGDQRRGQSLIVWAISEGREAAHHIDNFLMGESDLPTKGDGDLPRV
>CP030104.1|AWX43895.1|990975_992961_-|hypothetical-protein
MRFFCIALLLLVRLSVFAQQDSLPPVQQIDTVGQNGPKVLKSKEAIEKDSVLISDYKIISYSRDTIVLDTTLTIKKEYKYNYLRKDDFELMPFANIGQPYNSLGRTFSENTFYPQLGALTKHFNYMEVEDIDYYHVPTPMTELMFKTTLEQGQLLDALLTFNINKGFNASIAYKGFRSLGKYRFNQAQSGNFRTTFNYTTNNKKYIVRGHITAQDIESEENGGLEDRAQFEGGTPDFEDRFRIDVLYTDATNRVQGRRYFLDQQFKLFNYKKDSTSKKPTALVIGHEFNYETKYYQFTQTEQNNAFGEDVFSEPIDDRARLKTMFNKLSIEFSNRVLGKISGNASLYNYNYFFNSILVTDEGIIGNQLKGEEIAIGGTYSKDLGRLKLDGSINYNILGELTGNTFNTSVQYIINKNNLFFGSINASSRMPNFNYLLYQSDYENFNWQNTDNFEKQQIQNIAFGFDSFFFGNIKAEYSAIDNYTYFASSEAEQEEIDNGLETAFVKPIQETSTINHLRIKYFKEFKWRKWALANTVLYQDVTQDTQVLNVPQVVTRNTLYFSTDAFKKAMFLQTGVTLKYFTSYNMNAYNPLLSEFYTQNREEFGGFPMMDFFINAKVRQTRIYLKAEHFNSSFSEPNFYAAPNYPYRDFVIRFGLVWNFFS
>CP030104.1|AWX43896.1|993103_994585_-|hypothetical-protein
MKNKFYISTIMALMLLTFSCEDDFLDREPSEFITQNQITDAAVTNPGIVAGTIAGIYSLMIQTETGGTTGDDDFGQKGNDIFGDMLCGDMALSRSTFGWYRASITEFQGPQDFTFGDNRQVWRYYFRLVRSANSAISAFGGSDAVPELEEARYNLGQALAIRAHSYFYLTQYFANDYNPSAEILPLYDDIEDVNGPKVATSVIYDLMESDLTSAISLLEGFGRSAKNEINQDVARGILAYVLGSRRDRWGDVASQTGAVIDGGAFPLMTAEEIVGGFNDVNTPGWMWGIDLTSEIGLNLVSWWGQMDSFTFSYAWAGDYKAIDQDLYDAISADDARKAQFNDDPENRFLLPLDKFYDPGRVIGGQRFIETDYIYMRVAEMYLLNAEALAKSGNEPGARERLKELLDLRIPDSSYIDGLAGQDLLDEIYLQTRIELWGEGKSYLAMKRNQATITRGPNHLSFVGIPIEHNDERLTFEIPFLEIQNNPFINTQNE

Crispr_ID: CP030104_4

• CRISPR_ID: CP030104_4
• CRISPR_location: 2638042-2638329
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of CP030104_4

Consensus_repeat	Method
TTCNCCTTGGATTCCCTGTTCNCCCTG	CRT

spacers of CP030104_4

>4.1|2638069|27|CP030104|CRT
CGGCCCTTGTGGCCCTTCGGGTCCGAC
>4.2|2638123|27|CP030104|CRT
GGGTCCTTCAGGTCCAATCTCACCTTG
>4.3|2638177|18|CP030104|CRT
TGGTCCTTCGGGTCCGAT
>4.4|2638222|18|CP030104|CRT
TGGTCCTTCGGGTCCGAT
>4.5|2638267|36|CP030104|CRT
CTCGCCTTGTGGCCCTTGCGGTCCTTCGGGTCCGAT

CRISPR arrays and Neighbor proteins around CP030104_4

CRISPR arrays

The CRISPR arrays of CP030104_4

>merge|CP030104|4|2638042-2638329|CRT
TTCACCTTGGATTCCCTGTTCGCCCTGCGGCCCTTGTGGCCCTTCGGGTCCGACTTCTCCTTGGATTCCCTGTTCGCCATGGGGTCCTTCAGGTCCAATCTCACCTTGTATACCTTGGATTCCCTGTTCGCCCTGTGGTCCTTCGGGTCCGATTTCACCTTGGATTCCCTGTTCGCCCTGTGGTCCTTCGGGTCCGATTTCTCCTTGGATTCCTTGTTCACCCTGCTCGCCTTGTGGCCCTTGCGGTCCTTCGGGTCCGATTTCTCCTTGGATTCCCTGTTCACCCTG

>CP030104|4|1|2638042-2638329|CRT
TTCACCTTGGATTCCCTGTTCGCCCTG	CGGCCCTTGTGGCCCTTCGGGTCCGAC
TTCTCCTTGGATTCCCTGTTCGCCATG	GGGTCCTTCAGGTCCAATCTCACCTTG
TATACCTTGGATTCCCTGTTCGCCCTG	TGGTCCTTCGGGTCCGAT
TTCACCTTGGATTCCCTGTTCGCCCTG	TGGTCCTTCGGGTCCGAT
TTCTCCTTGGATTCCTTGTTCACCCTG	CTCGCCTTGTGGCCCTTGCGGTCCTTCGGGTCCGAT
TTCTCCTTGGATTCCCTGTTCACCCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP030104.1|AWX45370.1|2649938_2650217_+|Sec-independent-protein-translocase-protein-TatA	unknown	unknown	gnl|CDD|224739
CP030104.1|AWX45367.1|2645976_2646774_+|hypothetical-protein	unknown	unknown	gnl|CDD|274948
CP030104.1|AWX45362.1|2636649_2637300_-|hypothetical-protein	unknown	unknown	unknown
CP030104.1|AWX45360.1|2634659_2635394_-|hypothetical-protein	unknown	unknown	gnl|CDD|350622
CP030104.1|AWX45358.1|2633076_2633469_+|hypothetical-protein	unknown	unknown	gnl|CDD|293786
CP030104.1|AWX45355.1|2628329_2629145_-|Methionyl-aminopeptidase	unknown	unknown	gnl|CDD|235576
CP030104.1|AWX45372.1|2650758_2651400_-|Caffeoyl-CoA-O-methyltransferase	unknown	unknown	gnl|CDD|226607
CP030104.1|AWX45353.1|2627150_2627915_-|Demethylmenaquinone-methyltransferase	unknown	unknown	gnl|CDD|369777
CP030104.1|AWX45366.1|2645246_2645987_+|hypothetical-protein	unknown	unknown	gnl|CDD|274948
CP030104.1|AWX45361.1|2635471_2636647_-|hypothetical-protein	unknown	unknown	gnl|CDD|372639
CP030104.1|AWX45368.1|2646868_2647372_+|hypothetical-protein	unknown	unknown	unknown
CP030104.1|AWX45356.1|2629206_2631294_-|Alpha-glucosidase	unknown	unknown	gnl|CDD|371140
CP030104.1|AWX45369.1|2647432_2649748_+|Membrane-alanyl-aminopeptidase	unknown	unknown	gnl|CDD|341067
CP030104.1|AWX45365.1|2642561_2645018_-|Glycoprotein-gp2	unknown	unknown	unknown
CP030104.1|AWX45359.1|2633857_2634622_-|hypothetical-protein	unknown	unknown	gnl|CDD|320692
CP030104.1|AWX45354.1|2628033_2628318_-|hypothetical-protein	unknown	unknown	gnl|CDD|275083
CP030104.1|AWX45371.1|2650220_2650805_+|Undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl|CDD|239489
CP030104.1|AWX45364.1|2641393_2642560_-|hypothetical-protein	unknown	unknown	gnl|CDD|372639
CP030104.1|AWX45363.1|2638362_2640879_+|hypothetical-protein	unknown	unknown	unknown
CP030104.1|AWX45357.1|2631351_2632869_-|Phosphoglycerate-mutase-(2,3-diphosphoglycerate-independent)	unknown	unknown	gnl|CDD|235463

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP030104.1|AWX45370.1|2649938_2650217_+|Sec-independent-protein-translocase-protein-TatA	gnl|CDD|224739	COG1826, TatA, Sec-independent protein secretion pathway components [Intracellular trafficking and secretion].	7.39392e-12
CP030104.1|AWX45367.1|2645976_2646774_+|hypothetical-protein	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	5.26228e-12
CP030104.1|AWX45360.1|2634659_2635394_-|hypothetical-protein	gnl|CDD|350622	cd14847, DD-carboxypeptidase_like, Uncharacterized proteins of the MEROPS peptidase family M15, subfamily B. This family of uncharacterized proteins similar to D-Ala-D-Ala carboxypeptidase pdcA (Myxococcus-type) are zinc-binding enzymes that belong to the peptidase M15 subfamily B. The enzyme D-Ala-D-Ala carbozypeptidase catalyzes carboxypeptidation reactions involved in bacterial cell wall metabolism.	2.45932e-66
CP030104.1|AWX45358.1|2633076_2633469_+|hypothetical-protein	gnl|CDD|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	1.06466e-14
CP030104.1|AWX45355.1|2628329_2629145_-|Methionyl-aminopeptidase	gnl|CDD|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	4.51862e-122
CP030104.1|AWX45372.1|2650758_2651400_-|Caffeoyl-CoA-O-methyltransferase	gnl|CDD|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	4.56765e-55
CP030104.1|AWX45353.1|2627150_2627915_-|Demethylmenaquinone-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	2.786e-18
CP030104.1|AWX45366.1|2645246_2645987_+|hypothetical-protein	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	7.4054e-09
CP030104.1|AWX45356.1|2629206_2631294_-|Alpha-glucosidase	gnl|CDD|371140	pfam10566, Glyco_hydro_97, Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.	3.29525e-139
CP030104.1|AWX45371.1|2650220_2650805_+|Undecaprenyl-diphosphate-phosphatase	gnl|CDD|239489	cd03395, PAP2_like_4, PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	6.72391e-41
CP030104.1|AWX45369.1|2647432_2649748_+|Membrane-alanyl-aminopeptidase	gnl|CDD|341067	cd09604, M1_APN_like, Peptidase M1 family similar to aminopeptidase N catalytic domain. This family contains bacterial M1 peptidases with smilarity to the catalytic domain of aminopeptidase N (APN; CD13; alanyl aminopeptidase; EC 3.4.11.2), a type II integral membrane protease belonging to the M1 gluzincin family. APN preferentially cleaves neutral amino acids from the N-terminus of oligopeptides and, in higher eukaryotes, is present in a variety of human tissues and cell types (leukocyte, fibroblast, endothelial and epithelial cells). APN expression is dysregulated in inflammatory diseases such as chronic pain, rheumatoid arthritis, multiple sclerosis, systemic sclerosis, systemic lupus erythematosus, polymyositis/dermatomyosytis and pulmonary sarcoidosis, and is enhanced in tumor cells such as melanoma, renal, prostate, pancreas, colon, gastric and thyroid cancers. It is predominantly expressed on stem cells and on cells of the granulocytic and monocytic lineages at distinct stages of differentiation, thus considered a marker of differentiation. Thus, APN inhibition may lead to the development of anti-cancer and anti-inflammatory drugs. APNs are also present in many pathogenic bacteria and represent potential drug targets. Some APNs have been used commercially, such as one from Lactococcus lactis used in the food industry. APN also serves as a receptor for coronaviruses, although the virus receptor interaction site seems to be distinct from the enzymatic site and aminopeptidase activity is not necessary for viral infection. APNs have also been extensively studied as putative Cry toxin receptors. Cry1 proteins are pore-forming toxins that bind to the midgut epithelial cell membrane of susceptible insect larvae, causing extensive damage. Several different toxins, including Cry1Aa, Cry1Ab, Cry1Ac, Cry1Ba, Cry1Ca and Cry1Fa, have been shown to bind to APNs; however, a direct role of APN in cytotoxicity has been yet to be firmly established.	5.31193e-134
CP030104.1|AWX45361.1|2635471_2636647_-|hypothetical-protein	gnl|CDD|372639	pfam13585, CHU_C, C-terminal domain of CHU protein family. The function of this C-terminal domain is not known; there are several conserved tryptophan and asparagine residues.	1.24393e-28
CP030104.1|AWX45354.1|2628033_2628318_-|hypothetical-protein	gnl|CDD|275083	TIGR04256, conserved_hypothetical_protein, GxxExxY protein. Members of this protein family average about 130 residues in length and include an almost perfectly conserved motif GxxExxY. Members occur in a wide range of prokaryotes, including Proteobacteria, Perrucomicrobia, Cyanobacteria, Bacteriodetes, Archaea, etc.	2.70788e-33
CP030104.1|AWX45364.1|2641393_2642560_-|hypothetical-protein	gnl|CDD|372639	pfam13585, CHU_C, C-terminal domain of CHU protein family. The function of this C-terminal domain is not known; there are several conserved tryptophan and asparagine residues.	7.18505e-22
CP030104.1|AWX45359.1|2633857_2634622_-|hypothetical-protein	gnl|CDD|320692	cd07333, M48C_bepA_like, Peptidase M48C Ste24p bepA-like, integral membrane protein. This family contains peptidase M48C Ste24p protease bepA (formerly yfgC)-like proteins considered to be putative metallopeptidases, containing a zinc-binding motif, HEXXH, and a COOH-terminal ER retrieval signal (KKXX). They proteolytically remove the C-terminal three residues of farnesylated proteins. They are integral membrane proteins associated with the endoplasmic reticulum and golgi, binding one zinc ion per subunit. In eukaryotes, Ste24p is required for the first NH2-terminal proteolytic processing event within the a-factor precursor, which takes place after COOH-terminal CAAX modification (C is cysteine; A is usually aliphatic; X is one of several amino acids) is complete. Mutation studies have shown that the HEXXH protease motif, which is extracellular but adjacent to a transmembrane domain and therefore close to the membrane surface, is critical for Ste24p activity. Several members of this family also contain tetratricopeptide (TPR) repeat motifs, which are involved in a variety of functions including protein-protein interactions. BepA has been shown to possess protease activity and is responsible for the degradation of incorrectly folded LptD, an essential outer-membrane protein (OMP) involved in OM transport and assembly of lipopolysaccharide. Overexpression of the bepA protease causes abnormal biofilm architecture.	8.55215e-51
CP030104.1|AWX45357.1|2631351_2632869_-|Phosphoglycerate-mutase-(2,3-diphosphoglycerate-independent)	gnl|CDD|235463	PRK05434, PRK05434, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.	0

Protein sequences

>CP030104.1|AWX45362.1|2636649_2637300_-|hypothetical-protein
MKKVIILGLLFSFFKVVAQTPTAGDLVGIHNVTTLEMNSITNPIEGSMVFNTTTSSMHFYSNAAWVEIPNVANVYVGAFQITGTGNQVINGLPFEPSSITFTAYANVESLNINSDNGTNNNNNGIANSFGSMNGFARNDNGSISEQVIYVGGSGNSINDISRYASSSHSIGLRYGNQNGDNLGVTSATVTSFNNDGFTLNTDSFADGIVVLFQAYR
>CP030104.1|AWX45361.1|2635471_2636647_-|hypothetical-protein
MFKNNQHRGLRVLGLMFMIFNLMSGQDAFHNFGNLQFHGNTSVGFHIDLIDDGVFDENLGLTGFYSENQLNISGTSNPVFNDIEIVTENGLYLNTWVGIKNNANFIIGNVLTDKSSSGSYLNFIDDAFFTGTGELTHVNGYAGATNKELITFPVGDGQQLRYLTLTSDAINSLARCAYYREDPNNSTSLGQQFDTANKEFDDLQISEFEFWRLESSQPSAITLTWNVSSNISLLTESTEGLLVVGWNKTENRWESLGNTSITGNLESGNITSNSFLPNDYEIVTLGGTESLLETFSVLELDNYFMTPNNDGTNDFLEIDGIENFPNNILNIYNRYGILVYSKLNYNNEFDGKSNQNAAISRNSGLAAGVYFYVLTLTDSKEKFQGYLYLSQ
>CP030104.1|AWX45360.1|2634659_2635394_-|hypothetical-protein
MKRRTFIKKTSISGLACTLPAIYPILPNTDYSVLELMGKEEIELFGEGINLRKEAYEAFLNMKKSAYSDGFDIKMVSSFRDYYRQEAIWERKYLRYTEDNDMQPLDAIDKIIEYSTIPGTSRHHWGTDIDIINGYANVSENVLDPQKFEQGGPFEAFKLWLDENSEKFGFYLVYTNEPKRRGFKYEPWHYSYAPISIPMLTAFRKINILKLLQKEEFLGSEHFTTGFLKTYLQDNILDINQKLL
>CP030104.1|AWX45359.1|2633857_2634622_-|hypothetical-protein
MRRGSWKIRILIGLAIVAFAFFKRCNNKEENPYTGRVQNINMTPDQEIAIGLQSAPEMAQQHGGLYPDERMQSLVDAVGKKLVNNSIARETPYEYDFHLLADDSAINAFALPGGQCFITYALFSQLTEAQLAGVLGHEIGHVIGRHSAERIAESNFWQTLTMGASVGGDMGGLVSGIGQNTLLKNGRGDELESDELGVLFMIQAGYDPYEMIKVMEILKTAAGPNRVPEFQSTHPDPENRIEMIKEAIEKYSGR
>CP030104.1|AWX45358.1|2633076_2633469_+|hypothetical-protein
MKKTIITAAAAFLVVVTGVCANETATISNGTLESSIVSVELNSFCKAIVQGDTETVKKLIELGEDVNQKSLGMAPIHYAARYNKPEIMEMLISNGADVKKRCDKGYTAKKHAELSNAVEVLEVLKLAMKK
>CP030104.1|AWX45357.1|2631351_2632869_-|Phosphoglycerate-mutase-(2,3-diphosphoglycerate-independent)
MDKKVILMILDGWGKSPNPKVSAIDQANTPFIDSLYKKYANANLLTDGMNVGLPEGQMGNSEVGHMNLGAGRIVYQDLAKINKAVAENTLKEEKVLQDAFEHAKTHKKAVHFLGLVSNGGVHSHINHLKALIKASEQNGVKHSFVHAFTDGRDVDPKSGKGFLQDITDFCSDKNTKLASVVGRYYAMDRDKRWERVKMAYNLLVNHEGEKVSNIAKAMQKSYDEGVTDEFIKPLVVTDAENIPLAKIADGDIVIFFNFRTDRGRELTQVLSQKDFHEQNMHKLNLYYVTMTNYDDSFKEIKVVYDKENIKDTLGEVLARNGKMQIRIAETEKYPHVTFFFNGGREEPFNGEQRILCPSPKVATYDLKPEMSAYEIRDSIIPELEKGNSSFICLNFANPDMVGHTGVMEAAIKACETVDQCAKDIINVGLQHGYSTIVIADHGNCDTMINPDGSPNTAHTTNPVPLILVDDELKEIKDGVLGDIAPTILKMIGLPQPDLMTQKSLV
>CP030104.1|AWX45356.1|2629206_2631294_-|Alpha-glucosidase
MVAQRLKSPNGNFELVFQLENGVPTYRLSMNSEALIAKSKLGFELKDMPDFLDGFKLKTEEQKSFDETWEPVWGETKSIRNNYNELLVMLEQTTTGRFLNIRFRLFNDGLGFRYEFPEQPNLTYFVIKEERTQFALTGNHKTFWIPGDYDTQEYDYTTSKLSQISSLMDKAITPNASQKTFSKTGVQTALMMKADDGTYINVHEAALVEYPCMHLEVDETNFILESHLTPDAIGNKGYMQAPRNTPWRTIIASKNAGDILLSNITLNLNEPTEYEDTSWIRPVKYIGVWWEMITGKSSWAYTDIPSVRLGDTDFSVTKPNGRHAANTENVKMHIDFAAEHGFDQVLVEGWNEGWEDWFGKSKDFVFDFLTPYPDFDVVGLRDYAKSKNVRLMMHHETSGAIRNYERFMDKAYQFMVDNNYNAVKSGYVGDIIPRGEHHYGQWAINHYLYAVTKAAEYKIMVNAHEAVRPTGLSRTYPNLIGNESARGTEYEAFGGSNADHTTILPFTRLIGGPMDYTPGIFEPDVSKYNPNNRSWVNTTIARQLALYVTMYSPLQMAADLPETYNKHLDAFQFIKDVALDWDNSLVLEAEPGDFITYARKEKGTNNWFVGRTNDEQPRNSFITFDFLDSDKDYLATVYSDAKNAHYRDNPKAYEIKKYHVTQKSNLKLYCASGGGYAISIFEVKDKSQLKGLKKL
>CP030104.1|AWX45355.1|2628329_2629145_-|Methionyl-aminopeptidase
MIKIKTSEEIELMRESALVVSKTLGMLASEIKPGANPLKLDKLAEEFIQEQGAKPGFLGMYDFPNTLNWSPNAQVVHGIPDNEPLKEGDIISVDCGAFKNGYYGDHAYTFEVGEVADETRKLLKITKESLYVGIREFKEGNRVGDVGYAIQKYCENHGYGIVRELVGHGLGKELHEDPQMPNYGKRGRGKKFVEGMVVAIEPMVNMGTRRIKQLKDGWTILTVDGKPSAHFEHDVALIDGKPELLSTFQYIYDALGITSDEEAEFRRHEFH
>CP030104.1|AWX45354.1|2628033_2628318_-|hypothetical-protein
MSDKLLYKDESYFVIGLCMDVHNELGKGFSESVYADALEIELGINGVPYQKEVNYRINYKGKVLKHHYYADFVIDNKIILELKAIEKIASGHVK
>CP030104.1|AWX45353.1|2627150_2627915_-|Demethylmenaquinone-methyltransferase
MSSLFKFFLNLIPRPWLIKISYWARPLLSFLLKGKQFTDPIDGKSFRTFLPYGYENPRENVLSPSTLSLERHRLLWLYLKNETEFFTKSLKVLHFAPEQAFYKRFKNLSNIEYTTTDLNSPLAEIKADICDLPFDDNSFDVILCNHVLEHIPNDTKAMEELYRILAPDGWGIFQIPQDLKREKTFEDDSIIDKKERTRIFGQYDHVRIYGIDYFDKLRSIGFKVEEVNYTKQLSQENVEKYRLAKGEIIPLVRK
>CP030104.1|AWX45363.1|2638362_2640879_+|hypothetical-protein
MRSFGSNLSLRSLRSLWSNLSLNALFSLRSNFTLDTLFALGSLRSLGSNFTLYSLNSLFSLSSFRSDFSLFTLDSLFALGSLWPFRSDFSLYSLFSLRSLRSLGSNLSLYSLFSLWSFGSNFTLYSLFSLWSFGSNFTLYSLNSLFTLRSLGSNLSLDSLLTLGSLWSDFSLDSLFTLRSLGSDFTLDTLLTLGSLRSFGSDLSLYSLFALWSFRSNFSLDTLLTLGSLRSFGSDFTLNSLFALGSFGSDFTLDALFALRPLWSLGSDFTLYSLFSLDSLLALWSFGPDFSLNSLFALRSLRSFGSDLALDTLLALWSFGSDFSLFSLDSLLTLNSLFSLRSLWSFGSDFTLDSLFSLDSLFTLLALWPFWSNFSLYALDALFALRSFWSNFSLDALFALWSLRSFGSDFTLYSLLALDSLFALGSLRSDFTLYSLWSLRSFGSDFSLNSLFALGSFRSNLTLYTLDSLFTLLALWPFWSNFSLYALDALFALWSLGSDFSLNSLFALGSYLSLDSLRPLRSFGSDFTLDSLFALGSFRPNLTLYTLDSLFTLLALWPFWSNFSLYALDALFALRPLRSLGSNFTLDSLLALWSLGSDFSLNSLFALRSFRSDFTLFSLDSLLALRSLRSFGSDFSLNSLNSLLTLGSFGSDFTLYSLFSLYSLFSLRPFGSDFSLDSLFALGSLRSLWSNLSLNALFSLDALFALGSLWPFWSDFTLYSLNSLFALRSFRSDFTLFSLDSLLTLRPFWSNFSLYALDALFALRSLRSLGSNLTLYSLFSLYSLFALWSFRSNFSLYSLLALWSLGSNLSLDSLLALRSVGSNLSLNSLFSLWPFGSS
>CP030104.1|AWX45364.1|2641393_2642560_-|hypothetical-protein
MNPPLYIPFLLLFGFTQAQNALYNSGNIRIHPNGNLGFHTNLINDTAFDQNDGLAGFYGNATLQVEGSISPIFNDAEFMVSNDIFLQNSVNVQNNVNFVEGNVLSPLNDQTINLNFTSNGFFTGENDANKVTGFAAITDRQFFSFPVGDENQLRPLMLDSQSDTPLAFCAYFFENPSNPISIAESYNVEEKVRDIGTVNNKEFWIVQSDVPATVTVSWNQRSALGAIPNTTLDAIILVGWSKQSNQWVAIGNSAQSGDENQGFLTSQTFVPSDYEAITFGTVPLPTDTFAVNNPTLGNYFLSPNGDGTNDFLVIEGMSESPNNALRIFNRFGQKVFEKINYVDEFSGFTNSGSFLLNKDIGLPEGIYYYLATLDDLNLEYQGFIFLDR
>CP030104.1|AWX45365.1|2642561_2645018_-|Glycoprotein-gp2
MIVGLLIITSANGQIKIGENPQNLDPASVLELESTSRALVITRVTDTQMNNIVPLRGALVYNTDQECIHYYNGIGWVNICEALDNSFTTTTEAIVNTASEDNTIAITQVDDNYNFEVNQIRGENVVPRTLFGSNLAIESITDQELQNGSVTRAKLAEGSTGISGELLRWDGAVWTLTNENSLNISEVDGEIGNEVTGPADGTLELSGGGITGNPFLLDVSPDGITNAELADNAVTSNNIFDGTILDADIAAAAAVQGTKIAPDFGAQNVSTTGTLNSGSATIAGTISSTGTATVGANTITNIDGANGQVLTTDGAGNATWQNTSSAAVQTTTAIDGNGLAATPLDLADNAVTSVKIADGAILDADIAAAAAVQGTKIAPDFGAQNVSTTGTLNSGSATIAGTISSTGTATVGANTITNIDGANGQVLTTDGAGNATWQNTSSAAVQTTTAIDGNGLAATPLDLADNAVTSVKIADGAILDADIAAAAAVQGTKIAPDFGAQNVSTTGTLNSGSATIAGTISSTGTATVGANTITNIDGANGQVLTTDGAGNATWQNTSSAAVQTTTAIDGNGLAATPLDLADNAVTSVKIADGAILDADIAAAAAVQGTKIAPDFGAQNVSTTGTLNSGSATIAGTISSTGTATVGANTITNIDGANGQVLTTDGAGNATWQNTSSSTVQTTTAIDGNGLAATPLDLADNAVTLPKIADGTAAGQLMQWDGINWVLIDDGALDVTDEIVFKGRVLAASGVTGAYTINDPTITATSIIQLTVEENPSGNPIIIQLTNQGLGTFSVQINEFTGPGFTEINANWQYIVVNP
>CP030104.1|AWX45366.1|2645246_2645987_+|hypothetical-protein
MKNTILLVILLAFTSISFAQDNRQVLRGKVLYKGGNVPNENVINSTAETATITNDDGQFSILVKEGDQLVFTAVNFQLEVITVTPEMLNNNRLVVEVSEKVTRLDEVVITPENQKKFLEVKNENFKQFEYEIDRTTEVENIAESQTTRGMRDGLNFVNIFKAMFNSNRNDGVDQEPLKVSEVLRQIYDDQFFVVDLKLPQDKIDAFLIYCDDKVPSQTLLRKENEFQLIDFLVTHSKTFLAELNEE
>CP030104.1|AWX45367.1|2645976_2646774_+|hypothetical-protein
MRSKLFFFLSVAVIFASNAQKSNQKEIKGKVYSKDKDVVGVVVQNITSNSAVITGIDGNFSILAKLSDTLIFSAVQFKRKLLPVTEELLNTKSVTVILEEFVNELKEVVVKPFNLSGDLGQDLGGLELEKNVSAEALGLPNAHRKIPTQSERKLQQSTFGKFNPSMILAPPLDPIINAITGRTKMLKNRVKVDKAYARTQRVQDVYIDSLFVTTFKIPAEKINDFMYFCEVDEKFQQTVDSKDRLKILDYLISRSRVYREVNNLD
>CP030104.1|AWX45368.1|2646868_2647372_+|hypothetical-protein
MKKSLIVIIFLILPLLSFTSHKFYLSVTNMAYSEKNSSFQITSRIFIDDLEEVLEERYGVTTALGTKNETKVANEYIEKYLRAKFVVELNGEAVKYTFLGKEYDNDVVICYMEMTDIELSNLESIAVQNEILTDMFEEQQNIVHLKWNGQKRSFVLFRENNKGMLNL
>CP030104.1|AWX45369.1|2647432_2649748_+|Membrane-alanyl-aminopeptidase
MNKIKYCFASLLFLFGAMAIAQEEGEAKEERKPGHYNQSKFKQLYEEFSTPNTYRSASGAPGPDYYQQQADYKMNIELDDKNAKIYGEETITYHNNSPDDLEFLWVQLDQNVRTKDSKSLLRNGDGVNFAYTAGNFAKTYVTGPFDGGFNIEFVKDSNGKPLSYTINQTMMRLNIPQPLKSGEKMSFSIKWWYNIPDHTVDRARSGYEYFAKDGNRAYVIAQFFPRMAVYSDVEGWQNHQFWGSGEFALPFGNYDVNITVPADHVLDATGVLQNRDEVFSKEMMKRYKEASKSYDKPVIIVSQAEAEAAEKGFSDKKKTWKFKATNVRDYGFATSRKFIWDMQAVKVGGKDVMAVSLYPKEGNPLWEEQSTKAVVQTLETYSKHTFDYPYHKAISVHAKNQGMEYPMICWNYGRPNEDGTYSDRTKYGMISVIIHEVGHNFFPMIVNSDERQWGWMDEGLDTFMQYLAEQEFGKNYPDVIAPNANYPSRRGAPEKIVPYMSGDQDFMSPIMSNPENVYKLGPNAYGKPATGLNILRETVMGKELFDHAFKTYAQRWKFKHPTPEDFFRTMEDASAVDLDWFWRGWFYTTDYVDIGVKGVKKYYVSNTPTKEMEKYMADRNLTEADMPPLVYLAEEDSEDFTPELKGKSPTETSKNLKEFMMDNMTESERAQVKEPKYFYEVTFDKPGGMPMPLIVEYTYADGSKENITYPAEIWRKNDAEVSRVISSQKELVGIVIDPKLETADIDTTNNSWPMKEEKSDFDKFKENIKGE
>CP030104.1|AWX45370.1|2649938_2650217_+|Sec-independent-protein-translocase-protein-TatA
MHFLFISGAEIFFILFIVVMVFGADKIPGIAKGLGKGMRQLRDATDDIKREIQKSADKQGIDTDFTKDIRKELEEVKKNVDEVTGAVKRSTK
>CP030104.1|AWX45371.1|2650220_2650805_+|Undecaprenyl-diphosphate-phosphatase
MLKKILEWDRDTFVYLNSLGIEDYDVFWSTVTSITTWIPLFILFIALLFLKFPILEALYKLLTVLCLVAFIIFITDLTKTAVARLRPNNTEEINTLIRILKSPTDFSFFSGHAASSFSITVLIFLFLRKKLKWVVLFFIWPMLFATSRIYVGVHYPVDIIVGALVGIFSGLLFYKLYNRFIPPYLKSTRPSRVE
>CP030104.1|AWX45372.1|2650758_2651400_-|Caffeoyl-CoA-O-methyltransferase
MHFLSESLENYINNNSETEPDILRELTRETHLKVVQPRMITGHFQGRVLSLLSKIISPKHILEIGTYTGYSAISLAEGLKENGALHTIEINEELYKMQRKYFDKSGFGSMIKQHTGDALDIVPKLDIYFDLIFIDAQKINYDAYFEAVIKKTKPGSVILSDNVLWSGKVIEPVSNSDKATAALIAYNQKLKNDPRVETVILPVRDGLTLSRVV

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP030104_4	4.2|2638123|27|CP030104|CRT	2638123-2638149	27	CP030104.1	2639725-2639751	0	1.0
CP030104_4	4.3|2638177|18|CP030104|CRT	2638177-2638194	18	CP030104.1	2639392-2639409	0	1.0
CP030104_4	4.4|2638222|18|CP030104|CRT	2638222-2638239	18	CP030104.1	2639392-2639409	0	1.0
CP030104_4	4.2|2638123|27|CP030104|CRT	2638123-2638149	27	CP030104.1	2639968-2639994	1	0.963
CP030104_4	4.3|2638177|18|CP030104|CRT	2638177-2638194	18	CP030104.1	2637871-2637888	1	0.944
CP030104_4	4.3|2638177|18|CP030104|CRT	2638177-2638194	18	CP030104.1	2639842-2639859	1	0.944
CP030104_4	4.3|2638177|18|CP030104|CRT	2638177-2638194	18	CP030104.1	2640139-2640156	1	0.944
CP030104_4	4.4|2638222|18|CP030104|CRT	2638222-2638239	18	CP030104.1	2637871-2637888	1	0.944
CP030104_4	4.4|2638222|18|CP030104|CRT	2638222-2638239	18	CP030104.1	2639842-2639859	1	0.944
CP030104_4	4.4|2638222|18|CP030104|CRT	2638222-2638239	18	CP030104.1	2640139-2640156	1	0.944
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	CP030104.1	2639140-2639166	2	0.926
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	CP030104.1	2639914-2639940	2	0.926

1. spacer 4.2|2638123|27|CP030104|CRT matches to position: 2639725-2639751, mismatch: 0, identity: 1.0

gggtccttcaggtccaatctcaccttg	CRISPR spacer
gggtccttcaggtccaatctcaccttg	Protospacer
***************************

2. spacer 4.3|2638177|18|CP030104|CRT matches to position: 2639392-2639409, mismatch: 0, identity: 1.0

tggtccttcgggtccgat	CRISPR spacer
tggtccttcgggtccgat	Protospacer
******************

3. spacer 4.4|2638222|18|CP030104|CRT matches to position: 2639392-2639409, mismatch: 0, identity: 1.0

tggtccttcgggtccgat	CRISPR spacer
tggtccttcgggtccgat	Protospacer
******************

4. spacer 4.2|2638123|27|CP030104|CRT matches to position: 2639968-2639994, mismatch: 1, identity: 0.963

gggtccttcaggtccaatctcaccttg	CRISPR spacer
gggtccttcaggcccaatctcaccttg	Protospacer
************.**************

5. spacer 4.3|2638177|18|CP030104|CRT matches to position: 2637871-2637888, mismatch: 1, identity: 0.944

tggtccttcgggtccgat	CRISPR spacer
tggcccttcgggtccgat	Protospacer
***.**************

6. spacer 4.3|2638177|18|CP030104|CRT matches to position: 2639842-2639859, mismatch: 1, identity: 0.944

tggtccttcgggtccgat	CRISPR spacer
tggtccctcgggtccgat	Protospacer
******.***********

7. spacer 4.3|2638177|18|CP030104|CRT matches to position: 2640139-2640156, mismatch: 1, identity: 0.944

tggtccttcgggtccgat	CRISPR spacer
tggtccctcgggtccgat	Protospacer
******.***********

8. spacer 4.4|2638222|18|CP030104|CRT matches to position: 2637871-2637888, mismatch: 1, identity: 0.944

tggtccttcgggtccgat	CRISPR spacer
tggcccttcgggtccgat	Protospacer
***.**************

9. spacer 4.4|2638222|18|CP030104|CRT matches to position: 2639842-2639859, mismatch: 1, identity: 0.944

tggtccttcgggtccgat	CRISPR spacer
tggtccctcgggtccgat	Protospacer
******.***********

10. spacer 4.4|2638222|18|CP030104|CRT matches to position: 2640139-2640156, mismatch: 1, identity: 0.944

tggtccttcgggtccgat	CRISPR spacer
tggtccctcgggtccgat	Protospacer
******.***********

11. spacer 4.1|2638069|27|CP030104|CRT matches to position: 2639140-2639166, mismatch: 2, identity: 0.926

cggcccttgtggcccttcgggtccgac	CRISPR spacer
cggcccttgtggtccctcgggtccgac	Protospacer
************.**.***********

12. spacer 4.1|2638069|27|CP030104|CRT matches to position: 2639914-2639940, mismatch: 2, identity: 0.926

cggcccttgtggcccttcgggtccgac	CRISPR spacer
cggcccttgcggtccttcgggtccgac	Protospacer
*********.**.**************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP030104_1	1.3|172699|27|CP030104|CRISPRCasFinder	172699-172725	27	MG592671	Vibrio phage 2.275.O._10N.286.54.E11, partial genome	233364-233390	5	0.815
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	NZ_CP018472	Xanthomonas perforans strain LH3 plasmid pLH3.1, complete sequence	19287-19313	5	0.815
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	NZ_CP018726	Xanthomonas vesicatoria ATCC 35937 strain LMG911 plasmid pLMG911.1, complete sequence	92724-92750	5	0.815
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	NZ_CP018732	Xanthomonas gardneri strain ICMP 7383 plasmid pICMP7383.1, complete sequence	199851-199877	5	0.815
CP030104_4	4.2|2638123|27|CP030104|CRT	2638123-2638149	27	MG592473	Vibrio phage 1.101.O._10N.261.45.C6, partial genome	94728-94754	5	0.815
CP030104_4	4.2|2638123|27|CP030104|CRT	2638123-2638149	27	NC_047707	Uncultured phage_MedDCM-OCT-S38-C3 DNA, complete genome, group G9, isolate: uvMED-CGR-U-MedDCM-OCT-S38-C3	32610-32636	5	0.815
CP030104_1	1.1|172582|30|CP030104|CRISPRCasFinder	172582-172611	30	MT773557	Myoviridae sp. isolate BML_S_1 genomic sequence	128773-128802	6	0.8
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	MH020248	Mycobacterium phage Panamaxus, complete genome	2131-2157	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	MN062712	Mycobacterium phage Pocahontas, complete genome	2131-2157	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	KX640831	Mycobacterium phage Margo, complete genome	2131-2157	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	MG812492	Mycobacterium phage Lambert1, complete genome	2131-2157	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	MT776810	Gordonia phage BigChungus, complete genome	22670-22696	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	MK284519	Mycobacterium phage Norbert, complete genome	2131-2157	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	MN284906	Gordonia phage CherryonLim, complete genome	24407-24433	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	MK967385	Gordonia phage SheckWes, complete genome	22633-22659	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	MN586015	Gordonia phage Lauer, complete genome	23700-23726	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	MT776808	Gordonia phage Feastonyeet, complete genome	22670-22696	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	MK524496	Mycobacterium phage Veracruz, complete genome	2131-2157	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	MN062716	Gordonia phage Mayweather, complete genome	24283-24309	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	MH976517	Mycobacterium phage Popcicle, complete genome	2131-2157	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	KT326767	Mycobacterium phage Texage, complete genome	2131-2157	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	KM592966	Mycobacterium phage QuinnKiro, complete genome	2131-2157	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	MH316563	Mycobacterium phage Hookmount, complete genome	2131-2157	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	KX670828	Mycobacterium phage Todacoro, complete genome	2131-2157	6	0.778
CP030104_4	4.1|2638069|27|CP030104|CRT	2638069-2638095	27	MK494127	Mycobacterium phage Noella, complete genome	2131-2157	6	0.778
CP030104_4	4.2|2638123|27|CP030104|CRT	2638123-2638149	27	NC_021795	Cellulophaga phage phi17:1, complete genome	26448-26474	6	0.778
CP030104_1	1.1|172582|30|CP030104|CRISPRCasFinder	172582-172611	30	MN694154	Marine virus AFVG_250M77, complete genome	29189-29218	8	0.733
CP030104_1	1.1|172582|30|CP030104|CRISPRCasFinder	172582-172611	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	241082-241111	8	0.733

1. spacer 1.3|172699|27|CP030104|CRISPRCasFinder matches to MG592671 (Vibrio phage 2.275.O._10N.286.54.E11, partial genome) position: , mismatch: 5, identity: 0.815

gttaacgtatcagaatcacttgttgca	CRISPR spacer
cttaaggtatcagaagcacttgttcga	Protospacer
 **** ********* ********  *

2. spacer 4.1|2638069|27|CP030104|CRT matches to NZ_CP018472 (Xanthomonas perforans strain LH3 plasmid pLH3.1, complete sequence) position: , mismatch: 5, identity: 0.815

cggcccttgtggcccttcgggtccgac	CRISPR spacer
aggcccctgtcgcccttcgggtcccag	Protospacer
 *****.*** ************* * 

3. spacer 4.1|2638069|27|CP030104|CRT matches to NZ_CP018726 (Xanthomonas vesicatoria ATCC 35937 strain LMG911 plasmid pLMG911.1, complete sequence) position: , mismatch: 5, identity: 0.815

cggcccttgtggcccttcgggtccgac	CRISPR spacer
aggcccctgtcgcccttcgggtcccag	Protospacer
 *****.*** ************* * 

4. spacer 4.1|2638069|27|CP030104|CRT matches to NZ_CP018732 (Xanthomonas gardneri strain ICMP 7383 plasmid pICMP7383.1, complete sequence) position: , mismatch: 5, identity: 0.815

cggcccttgtggcccttcgggtccgac	CRISPR spacer
aggcccctgtcgcccttcgggtcccag	Protospacer
 *****.*** ************* * 

5. spacer 4.2|2638123|27|CP030104|CRT matches to MG592473 (Vibrio phage 1.101.O._10N.261.45.C6, partial genome) position: , mismatch: 5, identity: 0.815

gggtccttcaggtccaatctcaccttg	CRISPR spacer
ctttccttcagggccaatttcaccttg	Protospacer
   ********* *****.********

6. spacer 4.2|2638123|27|CP030104|CRT matches to NC_047707 (Uncultured phage_MedDCM-OCT-S38-C3 DNA, complete genome, group G9, isolate: uvMED-CGR-U-MedDCM-OCT-S38-C3) position: , mismatch: 5, identity: 0.815

gggtccttcaggtccaatctcaccttg	CRISPR spacer
aggtccttcaggtccaacatcaccgcg	Protospacer
.****************. ***** .*

7. spacer 1.1|172582|30|CP030104|CRISPRCasFinder matches to MT773557 (Myoviridae sp. isolate BML_S_1 genomic sequence) position: , mismatch: 6, identity: 0.8

gtatctggcaatacagatatcttttatgca	CRISPR spacer
ataactggcaatatagatatcttttaagat	Protospacer
.** *********.************ *  

8. spacer 4.1|2638069|27|CP030104|CRT matches to MH020248 (Mycobacterium phage Panamaxus, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
gatgccttgtgggcctgcgggtccgac	Protospacer
 .  ******** *** **********

9. spacer 4.1|2638069|27|CP030104|CRT matches to MN062712 (Mycobacterium phage Pocahontas, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
gatgccttgtgggcctgcgggtccgac	Protospacer
 .  ******** *** **********

10. spacer 4.1|2638069|27|CP030104|CRT matches to KX640831 (Mycobacterium phage Margo, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
gatgccttgtgggcctgcgggtccgac	Protospacer
 .  ******** *** **********

11. spacer 4.1|2638069|27|CP030104|CRT matches to MG812492 (Mycobacterium phage Lambert1, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
gatgccttgtgggcctgcgggtccgac	Protospacer
 .  ******** *** **********

12. spacer 4.1|2638069|27|CP030104|CRT matches to MT776810 (Gordonia phage BigChungus, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
atctccttgaggcccttcgggtcccac	Protospacer
   .***** ************** **

13. spacer 4.1|2638069|27|CP030104|CRT matches to MK284519 (Mycobacterium phage Norbert, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
gatgccttgtgggcctgcgggtccgac	Protospacer
 .  ******** *** **********

14. spacer 4.1|2638069|27|CP030104|CRT matches to MN284906 (Gordonia phage CherryonLim, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
atctccttgaggcccttcgggtcccac	Protospacer
   .***** ************** **

15. spacer 4.1|2638069|27|CP030104|CRT matches to MK967385 (Gordonia phage SheckWes, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
atctccttgaggcccttcgggtcccac	Protospacer
   .***** ************** **

16. spacer 4.1|2638069|27|CP030104|CRT matches to MN586015 (Gordonia phage Lauer, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
atctccttgaggcccttcgggtcccac	Protospacer
   .***** ************** **

17. spacer 4.1|2638069|27|CP030104|CRT matches to MT776808 (Gordonia phage Feastonyeet, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
atctccttgaggcccttcgggtcccac	Protospacer
   .***** ************** **

18. spacer 4.1|2638069|27|CP030104|CRT matches to MK524496 (Mycobacterium phage Veracruz, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
gatgccttgtgggcctgcgggtccgac	Protospacer
 .  ******** *** **********

19. spacer 4.1|2638069|27|CP030104|CRT matches to MN062716 (Gordonia phage Mayweather, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
atctccttgaggcccttcgggtcccac	Protospacer
   .***** ************** **

20. spacer 4.1|2638069|27|CP030104|CRT matches to MH976517 (Mycobacterium phage Popcicle, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
gatgccttgtgggcctgcgggtccgac	Protospacer
 .  ******** *** **********

21. spacer 4.1|2638069|27|CP030104|CRT matches to KT326767 (Mycobacterium phage Texage, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
gatgccttgtgggcctgcgggtccgac	Protospacer
 .  ******** *** **********

22. spacer 4.1|2638069|27|CP030104|CRT matches to KM592966 (Mycobacterium phage QuinnKiro, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
gatgccttgtgggcctgcgggtccgac	Protospacer
 .  ******** *** **********

23. spacer 4.1|2638069|27|CP030104|CRT matches to MH316563 (Mycobacterium phage Hookmount, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
gatgccttgtgggcctgcgggtccgac	Protospacer
 .  ******** *** **********

24. spacer 4.1|2638069|27|CP030104|CRT matches to KX670828 (Mycobacterium phage Todacoro, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
gatgccttgtgggcctgcgggtccgac	Protospacer
 .  ******** *** **********

25. spacer 4.1|2638069|27|CP030104|CRT matches to MK494127 (Mycobacterium phage Noella, complete genome) position: , mismatch: 6, identity: 0.778

cggcccttgtggcccttcgggtccgac	CRISPR spacer
gatgccttgtgggcctgcgggtccgac	Protospacer
 .  ******** *** **********

26. spacer 4.2|2638123|27|CP030104|CRT matches to NC_021795 (Cellulophaga phage phi17:1, complete genome) position: , mismatch: 6, identity: 0.778

gggtccttcaggtccaatctcaccttg	CRISPR spacer
tataccttgaggtccagtctcaccttg	Protospacer
 .  **** *******.**********

27. spacer 1.1|172582|30|CP030104|CRISPRCasFinder matches to MN694154 (Marine virus AFVG_250M77, complete genome) position: , mismatch: 8, identity: 0.733

gtatctggcaatacagatatcttttatgca	CRISPR spacer
atatctgataatacagatatcttttggttc	Protospacer
.******..****************.  . 

28. spacer 1.1|172582|30|CP030104|CRISPRCasFinder matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 8, identity: 0.733

gtatctggcaatacagatatcttttatgca	CRISPR spacer
gaatctggaaatacagatatatttttaatt	Protospacer
* ****** *********** ****  ..