CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP030110	Enterococcus faecium strain BM4105-RF chromosome, complete genome	2 crisprs	cas9,cas1,cas2,csn2,DEDDh,cas3,csa3,DinG,cas14j	1	2	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP030110_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030110_1

334524-335086

TypeII

II-A

Consensus_repeat	Method
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	PILER-CR
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CRISPRCasFinder
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CRT

8 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of CP030110_1

>merge|CP030110|1|334524-335086|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACTTTACCGATTGCCAACACTTCTAATCCAAAGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACAACTTTTCCATCTCTACCACCCTCTGGGAAGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACACAAGACTATGTTAGTGCTGCTTAGAGCTGGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACCTTATATGACAGCTTATAAAGTGTTATGTAGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACATGCCTCGAGTGCTGTCGTGTGTGTGCTGTGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACCTTTTCCTAATAATTTACAATCATCAATATGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACTTTAATAGTTAACGGAAATCACGATCGCGGGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACTTGATTTGTGTCCTCGATTTGCACTTTTAGTTTTAGAGCTATGCTGATTTGAATACTACTCTAGA

>CP030110|1|1|334524-335021|PILER-CR
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTACCGATTGCCAACACTTCTAATCCAAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AACTTTTCCATCTCTACCACCCTCTGGGAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ACAAGACTATGTTAGTGCTGCTTAGAGCTG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CTTATATGACAGCTTATAAAGTGTTATGTA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ATGCCTCGAGTGCTGTCGTGTGTGTGCTGT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CTTTTCCTAATAATTTACAATCATCAATAT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTAATAGTTAACGGAAATCACGATCGCGG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC

>CP030110|1|1|334524-335086|CRISPRCasFinder
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTACCGATTGCCAACACTTCTAATCCAAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AACTTTTCCATCTCTACCACCCTCTGGGAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ACAAGACTATGTTAGTGCTGCTTAGAGCTG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CTTATATGACAGCTTATAAAGTGTTATGTA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ATGCCTCGAGTGCTGTCGTGTGTGTGCTGT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CTTTTCCTAATAATTTACAATCATCAATAT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTAATAGTTAACGGAAATCACGATCGCGG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTGATTTGTGTCCTCGATTTGCACTTTTA
GTTTTAGAGCTATGCTGATTTGAATACTACTCTAGA

>CP030110|1|1|334524-335086|CRT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTACCGATTGCCAACACTTCTAATCCAAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AACTTTTCCATCTCTACCACCCTCTGGGAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ACAAGACTATGTTAGTGCTGCTTAGAGCTG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CTTATATGACAGCTTATAAAGTGTTATGTA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ATGCCTCGAGTGCTGTCGTGTGTGTGCTGT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CTTTTCCTAATAATTTACAATCATCAATAT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTAATAGTTAACGGAAATCACGATCGCGG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTGATTTGTGTCCTCGATTTGCACTTTTA
GTTTTAGAGCTATGCTGATTTGAATACTACTCTAGA

Protein	Signature genes	Signature genes Name	Protein_function
CP030110.1\|AWX46702.1\|327899_328028_-\|methanol-dehydrogenase	unknown	unknown	unknown
CP030110.1\|AWX46711.1\|340835_342275_-\|HTH-domain-containing-protein	unknown	unknown	gnl\|CDD\|375760
CP030110.1\|AWX46708.1\|335618_335984_+\|DUF1622-domain-containing-protein	unknown	unknown	gnl\|CDD\|377914
CP030110.1\|AWX46705.1\|332573_333440_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
CP030110.1\|AWX46709.1\|336144_337572_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|311953
CP030110.1\|AWX46714.1\|343945_344857_+\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|132175
CP030110.1\|AWX46716.1\|346611_346911_+\|malonate-decarboxylase-subunit-delta	unknown	unknown	gnl\|CDD\|188283
CP030110.1\|AWX46710.1\|338276_340829_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319775
CP030110.1\|AWX46698.1\|323647_324607_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
CP030110.1\|AWX46712.1\|342418_342781_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225197
CP030110.1\|AWX46713.1\|342968_343826_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
CP030110.1\|AWX46703.1\|328344_328542_+\|hypothetical-protein	unknown	unknown	unknown
CP030110.1\|AWX46706.1\|333436_333781_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
CP030110.1\|AWX46707.1\|335256_335622_+\|DUF1622-domain-containing-protein	unknown	unknown	gnl\|CDD\|377914
CP030110.1\|AWX46699.1\|324754_325615_+\|hypothetical-protein	unknown	unknown	unknown
CP030110.1\|AWX46700.1\|325639_325831_-\|hypothetical-protein	unknown	unknown	unknown
CP030110.1\|AWX48818.1\|333770_334433_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
CP030110.1\|AWX46715.1\|344863_346510_+\|malonate-decarboxylase-subunit-alpha	unknown	unknown	gnl\|CDD\|379906
CP030110.1\|AWX46704.1\|328550_332573_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
CP030110.1\|AWX46701.1\|326148_327843_-\|oleate-hydratase	unknown	unknown	gnl\|CDD\|237575

Protein	Function_ID	Function_description	E-value
CP030110.1\|AWX46714.1\|343945_344857_+\|ACP-S-malonyltransferase	gnl\|CDD\|132175	TIGR03131, malonate_mdcH, malonate decarboxylase, epsilon subunit. Members of this protein family are the epsilon subunit of malonate decarboxylase. This subunit has malonyl-CoA/dephospho-CoA acyltransferase activity. Malonate decarboxylase may be a soluble enzyme, or linked to membrane subunits and active as a sodium pump. The epsilon subunit is closely related to the malonyl CoA-acyl carrier protein (ACP) transacylase family described by TIGR00128, but acts on an ACP subunit of malonate decarboxylase that has an unusual coenzyme A derivative as its prothetic group.	8.48016e-67
CP030110.1\|AWX46708.1\|335618_335984_+\|DUF1622-domain-containing-protein	gnl\|CDD\|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	8.2154e-25
CP030110.1\|AWX46705.1\|332573_333440_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	6.57421e-121
CP030110.1\|AWX46709.1\|336144_337572_-\|DNA-binding-protein	gnl\|CDD\|311953	pfam08280, HTH_Mga, M protein trans-acting positive regulator (MGA) HTH domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions.	0.00286938
CP030110.1\|AWX46716.1\|346611_346911_+\|malonate-decarboxylase-subunit-delta	gnl\|CDD\|188283	TIGR03130, malonate_delta, malonate decarboxylase acyl carrier protein. Members of this protein family are the acyl carrier protein, also called the delta subunit, of malonate decarboxylase. This subunit has the same covalently bound prosthetic group, derived from and similar to coenzyme A, as does citrate lyase, although this protein and the acyl carrier protein of citrate lyase do not show significant sequence similarity. Both malonyl and acetyl groups are transferred to the prosthetic group for catalysis.	5.72696e-47
CP030110.1\|AWX46710.1\|338276_340829_+\|HAD-family-hydrolase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
CP030110.1\|AWX46698.1\|323647_324607_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	6.348e-54
CP030110.1\|AWX46712.1\|342418_342781_+\|hypothetical-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	1.06856e-20
CP030110.1\|AWX46713.1\|342968_343826_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.12473e-38
CP030110.1\|AWX46711.1\|340835_342275_-\|HTH-domain-containing-protein	gnl\|CDD\|375760	pfam18333, ssDNA_DBD, Non-canonical single-stranded DNA-binding domain. This domain is found in ThermoDBP, a non-canonical single-stranded DNA-binding protein in Thermoproteales. Single-stranded DNA-binding proteins are needed for DNA metabolism, sequestering and protecting transiently formed ssDNA during DNA replication and recombination, detecting DNA damage and recruiting repair proteins. The outer edge of the ssDNA-binding cleft, formed by this domain, has a strongly positive electrostatic surface potential because of the conserved basic residues R49, K54, R65, R80, R86, R90, K97, and R112.	3.55805e-38
CP030110.1\|AWX46706.1\|333436_333781_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.51394e-45
CP030110.1\|AWX46707.1\|335256_335622_+\|DUF1622-domain-containing-protein	gnl\|CDD\|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	1.12042e-21
CP030110.1\|AWX48818.1\|333770_334433_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.29943e-107
CP030110.1\|AWX46715.1\|344863_346510_+\|malonate-decarboxylase-subunit-alpha	gnl\|CDD\|379906	pfam16957, Mal_decarbox_Al, Malonate decarboxylase, alpha subunit, transporter. Mal_decarbox_Al is a family of Na+-transporting carboxylic acid decarboxylases.	0
CP030110.1\|AWX46704.1\|328550_332573_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
CP030110.1\|AWX46701.1\|326148_327843_-\|oleate-hydratase	gnl\|CDD\|237575	PRK13977, PRK13977, myosin-cross-reactive antigen; Provisional.	0

>CP030110.1|AWX48818.1|333770_334433_+|type-II-A-CRISPR-associated-protein-Csn2
MNLNFPLLEQPLSLEKATFLIVEDVTVFAKIVKWFYQYSESHELKLFNDKYKELKESDLLIITDVLGFDINSASTLKLIYADLERQLNEKVEVKSMIDKLTATISELIGYELLDHELDLEGDEITVLELFKALGIKIETRSDTIFEKLLELLQVYKYLSKKKLLVLINVCSYLTEEEISEVQNYISLYHMEVLFVEPRSIKGIKQFVLDKDYFLNLENMV
>CP030110.1|AWX46706.1|333436_333781_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETADERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNPTASQAMLKRLKSNNPKKGFVTLLTVTEKQFARMVYLSGERDTSVANSDKRVIYLGEDEDAES
>CP030110.1|AWX46705.1|332573_333440_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVNTHSKLAYVNNHLIFKNAEKTERLHLSEIDVLLLETTDITITTMLLKRLVDEKILVLFCDDKRLPVAKLLPFYSRHDSSLQLTRQLAWSPEKKGQVWTAIISQKIQNQSNFLQKQSFTEKAESIQELHEGLLEFDPTNREGHAARIYFQTLFGTKFTREENNEINAGLDYGYTLLLSMFAREIVKNGCMTQFGLKHANQFNDFNLASDFMEPFRPVIDEIVYRYRNCEFPVIKRRLFDLFTNKYSYGKKEMFLTNIVSDYTSKVIKVLNNETEGVPQFRI
>CP030110.1|AWX46704.1|328550_332573_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKEYTIGLDIGTNSVGWSVLTDDYRLVSKKMKVAGNTEKSSTKKNFWGVRLFDEGQTAEARRSKRTARRRLARRRQRILELQKIFAPEILKIDEHFFARLNESFLVLDEKKQSRHPVFATIKQEKSYHQTYPTIYHLRQALADSSEKADIRLVYLAMAHLLKYRGHFLIEGELNTENSSVTETFRQFLSTYNQQFSEADDKQTEKLDEAVDCSFVFTEKMSKTKKAETLLKYFPHEKSNGYLSQFIKLMVGNQGNFKNVFGLEEEAKLQFSKETYEEDLEELLEKIGDDYIDLFVQAKNVYDAVLLSEILSDSTKNTRAKLSAGMIRRYDAHKEDLVLLKRFVKENLPKKYRAFFGDNSVNGYAGYIEGHATQEDFYKFVKKELTGIRGSEVFLTKIEQENFLRKQRTFDNGVIPHQIHLTELRAIIANQKKHYPFLKEEQEKLESLLTFKIPYYVGPLAKKQENSPFAWLIRKSEEKIKPWNLPEIVDMEGSAVRFIERMINTDMYMPHNKVLPKNSLLYQKFSIYNELTKVRYQDERGQMNYFSSIEKKEIFHELFEKNRKVTKKDLQEFLYLKYDIKHAELSGIEKAFNASYTTYHDFLTMSENKREMKQWLEDPELASMFEEIIKTLTVFEDREMIKTRLSHHEATLGKHIIKKLTKKHYTGWGRLSKELIQGIRDKQSNKTILDYLINDDDFPHHRNRNFMQLINDDSLSFKKEIKKAQMITDTENLEEIVKELTGSPAIKKGILQSLKIVDEIVGIMGYEPANIVVEMARENQTTGRGLKSSRPRLKALEESLKDFGSQLLKEYPTDNSSLQKDRLYLYYLQNGRDMYTGAPLDIHRLSDYDIDHIIPRSFTTDNSIDNKVLVSSKENRLKKDDVPSEKVVKKMRSFWYDLYSSKLISKRKLDNLTKIKLTEEDKAGFIKRQLVETRQITKHVAGILHHRFNKAEDTNEPIRKVRIITLKSALVSQFRNRFGIYKVREINEYHHAHDAYLNGVVALALLKKYPQLAPEFVYGEYLKFNAHKANKATVKKEFYSNIMKFFESDTPVCDENGEIFWDKSKSIAQVKKVINHHHMNIVKKTEIQKGGFSKETVEPKKDSSKLLPRKNNWDPAKYGGLGSPNVAYTVAFTYEKGKARKRTNALEGITIMEREAFEQSPVLFLKNKGYEQAEIEMKLPKYALFELENGRKRMVASNKEAQKANSFLLPEHLVTLLYHAKQYDEISHKESFDYVNEHHKEFSEVFARVLEFAGKYTLAEKNIEKLEKIYKENQTDDLAKLASSFVNLMQFNAMGAPADFKFFDVTIPRKRYTSLTEIWQSTIIHQSITGLYETRIRMGK
>CP030110.1|AWX46703.1|328344_328542_+|hypothetical-protein
MILKSKAQKKRREQRCFKKADDGQSLILTCYIDLNATNIFIIAKITAFTIGVFVFSIMMSCWMKG
>CP030110.1|AWX46702.1|327899_328028_-|methanol-dehydrogenase
MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI
>CP030110.1|AWX46701.1|326148_327843_-|oleate-hydratase
MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSNDGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTAEEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDNITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVNRTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQEEEHVTVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGNPDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITSLGQKDVNMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSKVDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGEFVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE
>CP030110.1|AWX46700.1|325639_325831_-|hypothetical-protein
MHKFGLIPRNWLLNTVYQEVVSLPFSSESQGTISKNSFLCFMNIVTCDRGVGRGTPFIHNKRL
>CP030110.1|AWX46699.1|324754_325615_+|hypothetical-protein
MKQIQNKWNKRIIVMISSVCLFCLTVMLCLISTLANQHFMLEQNMQSDYAKKVAAEINQEIQSYHYEIGAPAEALEKIVSEELVQKNIELFIHNRYEKEPVELIGEKEVEEKLQEIINTYKQEEAEDDPFASEENNLLIYMTSGIFRRGIQSIYLMSFIDQILTIRERMVSFLPVISSILLVLLSGVFYLYRMSWKKVLWSFAVVIGGAGFQLLSLSVSLYLYDMTSQLDIRTQALQHLLDTYILSFIQFFSVVAIVEVVIAAGLWWIGKRVNTEKMVFSKRNEYK
>CP030110.1|AWX46698.1|323647_324607_+|IS30-family-transposase
MTYTHLTTDELVIIESYFKINQSIAKTAHCLNRSRQTIHKVYLFFKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI
>CP030110.1|AWX46707.1|335256_335622_+|DUF1622-domain-containing-protein
MFNTQLIGYLEWIIAILNICSIGILIAGIVLVLFKLFDWSHVKKNYAERNARNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVISYFLNQEIEDKEKQRRGEVG
>CP030110.1|AWX46708.1|335618_335984_+|DUF1622-domain-containing-protein
MTTELMQFLLPYFEKLVLGLDIFAICLLIWGVCLSIKDFLKYLFVHTEAKNDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIRTIISYFLNKEIGPVDVPNK
>CP030110.1|AWX46709.1|336144_337572_-|DNA-binding-protein
MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSYLLHVCKTTLLNDINNIKKEFEEQIVYTHREKDCYTLYFSEHIPRCKIMQQLTQNSLFLKTCLLYLEENEPDYLQLTECEFISVSKAYSLKKQVLAYFHDCGIEIDRYSPRFTEMERRLLLLNVAYRLGSFKSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQLCTVTIDPTFIEEIKKRPIYNYVESAWETTDFQTYYKKEEFAFILTLFNLCNYGCHSYQLIAEDFQQLHQVFIDNTPEIKELVATFETHFHQELFGNQPFERALIHLMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQTLFSSWAKRLPYDLRFNPNCMRAFVIELSGILRLTKERLTIYIVTNSDVHYLIYREALEAVTTFDFQVAPTIYASISDIKKYAQQSSNRVLCERTLYTPDAVQYENIIPISINTIERAIVSAVQNK
>CP030110.1|AWX46710.1|338276_340829_+|HAD-family-hydrolase
MNWYKLTVEDTLKNHQTSTEGLSQEERQKRLTDQGYNEIEARQQTKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEESLNGLKQLMGQEAIVLSNGMQVKIPAKELVKGDVIVLRAGYVVPADVRLIEVHDLLVEESILTGESEASEKNHSVLAAEESIGDQKNMAFSGTLVQFGSAVGVVVETGNTTEIGKINQALQSVEQQTTPLIKKINRLNKQIFQGILCLILFLVVFTTFRYGMDWHILLSAMIALVVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNEMTVVDVAAKEETRVLSIMKNCQELKTKEEQKIENLSGNPTELALIRHTETANLPLKKIEAKIPFSSEYKYMATMHTEEKGTVIYVKGAPEVLLAKSTLSYSEQEAWGQTATAFAKKGQRVLGFAYKKVDSKQELTHESLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKMITGDHKDTAKAIVEQIGLKHTAKVLEGIDLDLMSEEELTRQVPKVDVFARTTPEHKLRIVKALQKNGEIVGMTGDGVNDAPALKRADIGIAMGIKGSEVSKQAADMVLGDDNFHTIAKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALILNRPLPLSPVQILWVNMVTTITLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVALLIMVPAYLLAMQFEGQSLQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKSLFLSLGILALLQGMVIFLPIGQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREFSR
>CP030110.1|AWX46711.1|340835_342275_-|HTH-domain-containing-protein
MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTERTIFSDLQSIRSHLPEGWDIFSDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLFTKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACIRGKERAIRTFYHRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKANCRLDSSIHINSTLSSLYDSALKKLYLKEGIYLKDTELSFASFCFLESWNYNNNYGQEIARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLVLKYHESPILIEPLERQYHRFLETYDQQYAHLYQQKENLLNDLKKEMEINEPNYFLQLLSLLIQQTIFSIKPNLFNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDSLDIPIVYISSIPTKNELNRLTELTFKTFL
>CP030110.1|AWX46712.1|342418_342781_+|hypothetical-protein
MLTKKELIDHIDETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVLMSVPEEKIYDDASDHRIIDILDLKVDPELGGILRGKEGYFPAYHMNKEHWISVDLRKIEKLDELAGLIDESFKSTQ
>CP030110.1|AWX46713.1|342968_343826_-|LysR-family-transcriptional-regulator
MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELGVPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASVSIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAIPKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATLRSIFKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAKTMREFYLGK
>CP030110.1|AWX46714.1|343945_344857_+|ACP-S-malonyltransferase
MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENYQDTVFIQLALLTKAVFYLDEMEKNGIQPDIVAGHSIGAFCAAVACRSLTFENAAELVYHRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSIEGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKNTDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKFGVDKGIRTINLDQHGIDDATFLYQKWR
>CP030110.1|AWX46715.1|344863_346510_+|malonate-decarboxylase-subunit-alpha
MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLIAPGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKIDFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNLYTGFNTEETPTIVEAAAFKDGIVIVQVNEVVDKLPRVDIPGDWVDVVVKADQPYQLEALFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLKGKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSNRTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPAWQSLRNNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSEDTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDRLRDAGIVKLPEDLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS
>CP030110.1|AWX46716.1|346611_346911_+|malonate-decarboxylase-subunit-delta
MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKKESTVKICTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK

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Crispr_ID: CP030110_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030110_2

1123733-1123836

Orphan

II-A,II-B

Consensus_repeat	Method
AGTTTTAGATCTATGTTAATTTGAATGATACCAAATCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP030110_2

>merge|CP030110|2|1123733-1123836|CRISPRCasFinder
AGTTTTAGATCTATGTTAATTTGAATGATACCAAATCCATGACACAGATATTGACCTATGAGCAACAGTTTTAGATCTATGTTAATTTGAATGATACCAAATCC

>CP030110|2|2|1123733-1123836|CRISPRCasFinder
AGTTTTAGATCTATGTTAATTTGAATGATACCAAATCC	ATGACACAGATATTGACCTATGAGCAAC
AGTTTTAGATCTATGTTAATTTGAATGATACCAAATCC

Protein	Signature genes	Signature genes Name	Protein_function
CP030110.1\|AWX47449.1\|1135924_1136464_+\|hypothetical-protein	unknown	unknown	unknown
CP030110.1\|AWX47436.1\|1119032_1119800_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
CP030110.1\|AWX47437.1\|1119800_1120244_+\|hypothetical-protein	unknown	unknown	unknown
CP030110.1\|AWX47430.1\|1112846_1113215_-\|iron-chaperone	unknown	unknown	gnl\|CDD\|227933
CP030110.1\|AWX47440.1\|1123878_1125156_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
CP030110.1\|AWX47441.1\|1125279_1128363_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|227268
CP030110.1\|AWX47442.1\|1128483_1129467_+\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|372237
CP030110.1\|AWX47438.1\|1120452_1121043_-\|glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153234
CP030110.1\|AWX47446.1\|1132632_1134594_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227596
CP030110.1\|AWX47444.1\|1129704_1130094_+\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|372239
CP030110.1\|AWX47434.1\|1115982_1117572_+\|PTS-alpha-glucoside-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|273925
CP030110.1\|AWX47448.1\|1135700_1135928_+\|hypothetical-protein	unknown	unknown	unknown
CP030110.1\|AWX47439.1\|1121719_1122679_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
CP030110.1\|AWX47435.1\|1117616_1118948_+\|6-phospho-alpha-glucosidase	unknown	unknown	gnl\|CDD\|133434
CP030110.1\|AWX47433.1\|1115008_1115719_-\|hypothetical-protein	unknown	unknown	unknown
CP030110.1\|AWX47431.1\|1113364_1113859_+\|prolyl-tRNA-editing-protein	unknown	unknown	gnl\|CDD\|239827
CP030110.1\|AWX47443.1\|1129470_1129695_+\|hypothetical-protein	unknown	unknown	unknown
CP030110.1\|AWX47445.1\|1130113_1132618_+\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|315512
CP030110.1\|AWX47432.1\|1113882_1114893_+\|LD-carboxypeptidase	unknown	unknown	gnl\|CDD\|132883
CP030110.1\|AWX47447.1\|1134651_1135686_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|380090

Protein	Function_ID	Function_description	E-value
CP030110.1\|AWX47436.1\|1119032_1119800_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	4.51248e-40
CP030110.1\|AWX47447.1\|1134651_1135686_+\|CHAP-domain-containing-protein	gnl\|CDD\|380090	pfam18013, Phage_lysozyme2, Phage tail lysozyme. This domain has a lysozyme like fold. It is found in the tail protein of various phages probably giving them the ability to degrade the host cell wall peptidoglycan layer.	1.10625e-29
CP030110.1\|AWX47430.1\|1112846_1113215_-\|iron-chaperone	gnl\|CDD\|227933	COG5646, COG5646, Uncharacterized conserved protein [Function unknown].	1.63691e-24
CP030110.1\|AWX47440.1\|1123878_1125156_+\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	9.00006e-08
CP030110.1\|AWX47441.1\|1125279_1128363_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|227268	COG4932, COG4932, Predicted outer membrane protein [Cell envelope biogenesis, outer membrane].	1.4447e-30
CP030110.1\|AWX47442.1\|1128483_1129467_+\|conjugal-transfer-protein	gnl\|CDD\|372237	pfam12642, TpcC, Conjugative transposon protein TcpC. This family of proteins are annotated as conjugative transposon protein TcpC. The transfer clostridial plasmid (tcp) locus is part of some conjugative antibiotic resistance and virulence plasmids. TcpC was one of five genes whose products had low-level sequence identity to Tn916 proteins, having similarity to ORF13 homologs from Tn916, Tn5397, and CW459tet. This family of proteins is found in bacteria. Proteins in this family are typically between 302 and 351 amino acids in length.	1.91037e-44
CP030110.1\|AWX47438.1\|1120452_1121043_-\|glutamine-amidotransferase	gnl\|CDD\|153234	cd03140, GATase1_PfpI_3, Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.	6.83953e-75
CP030110.1\|AWX47446.1\|1132632_1134594_+\|hypothetical-protein	gnl\|CDD\|227596	COG5271, MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain [General function prediction only].	0.00636636
CP030110.1\|AWX47444.1\|1129704_1130094_+\|conjugal-transfer-protein	gnl\|CDD\|372239	pfam12648, TcpE, TcpE family. This family of proteins includes TcpE a conjugative transposon membrane protein.This family of proteins is found in bacteria. Proteins in this family are typically between 122 and 168 amino acids in length.	8.62001e-15
CP030110.1\|AWX47434.1\|1115982_1117572_+\|PTS-alpha-glucoside-transporter-subunit-IIBC	gnl\|CDD\|273925	TIGR02005, PTS-IIBC-alpha, PTS system, alpha-glucoside-specific IIBC component. This model represents a family of fused PTS enzyme II B and C domains. A gene from Clostridium has been partially characterized as a maltose transporter, while genes from Fusobacterium and Klebsiella have been proposed to transport the five non-standard isomers of sucrose. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
CP030110.1\|AWX47439.1\|1121719_1122679_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	6.348e-54
CP030110.1\|AWX47435.1\|1117616_1118948_+\|6-phospho-alpha-glucosidase	gnl\|CDD\|133434	cd05298, GH4_GlvA_pagL_like, Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases. Bacillus subtilis GlvA and Clostridium acetobutylicum pagL are 6-phospho-alpha-glucosidase, catalyzing the hydrolysis of alpha-glucopyranoside bonds to release glucose from oligosaccharides. The substrate specificities of other members of this subgroup are unknown. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP_PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases, which include 6-phospho-beta-glucosidases, 6-phospho-alpha-glucosidases, alpha-glucosidases/alpha-glucuronidases (only from Thermotoga), and alpha-galactosidases. Members of this subfamily are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
CP030110.1\|AWX47431.1\|1113364_1113859_+\|prolyl-tRNA-editing-protein	gnl\|CDD\|239827	cd04335, PrdX_deacylase, This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the YbaK and ProX proteins, and the prolyl-tRNA synthetase-editing domain (ProRS-INS), specifically hydrolyzes Ala-tRNA(Pro). In this CD, many of the eukaryotic editing domains are N-terminal and cis-acting, expressed from a multidomain ProRS, however, similar to the bacterial PrdX, the mammalian, amphibian, and echinoderm PrdX-like proteins are trans-acting, single-domain proteins.	5.59169e-32
CP030110.1\|AWX47445.1\|1130113_1132618_+\|conjugal-transfer-protein	gnl\|CDD\|315512	pfam12846, AAA_10, AAA-like domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.	4.96127e-142
CP030110.1\|AWX47432.1\|1113882_1114893_+\|LD-carboxypeptidase	gnl\|CDD\|132883	cd07062, Peptidase_S66_mccF_like, Microcin C7 self-immunity protein determines resistance to exogenous microcin C7. Microcin C7 self-immunity protein (mccF): MccF, a homolog of the LD-carboxypeptidase family, mediates resistance against exogenously added microcin C7 (MccC7), a ribosomally-encoded peptide antibiotic that contains a phosphoramidate linkage to adenosine monophosphate at its C-terminus. The plasmid-encoded mccF gene is transcribed in the opposite direction to the other five genes (mccA-E) and is required for the full expression of immunity but not for production. The catalytic triad residues (Ser, His, Glu) of LD-carboxypeptidase are also conserved in MccF, strongly suggesting that MccF shares the hydrolytic activity with LD-carboxypeptidases. Substrates of MccF have not been deduced, but could likely be microcin C7 precursors. The possible role of MccF is to defend producer cells against exogenous microcin from re-entering after having been exported. It is suggested that MccF is involved in microcin degradation or sequestration in the periplasm.	5.16056e-116

>CP030110.1|AWX47439.1|1121719_1122679_-|IS30-family-transposase
MTYTHLTTDELVIIESYFKINQSIAKTAHCLNRSRQTIHKVYLFFKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI
>CP030110.1|AWX47438.1|1120452_1121043_-|glutamine-amidotransferase
MKTAVTFLLEEYADWEGAYITSTLNQNEGWQNKTASIQSEVTSMGGLKTKIDYLIEQIPEKIDLFIMIGGNSWDIENHHLYLIIDKFLKTGVPVAAICGAVDYLAQSGLLQGYKHTGNMQFPWLESENYQNKEDFIEQQAVKDHNLITANGTAPIESTDLILQAVHFETEEIRQKTIRLYKLGYYDYYEKYGDSFS
>CP030110.1|AWX47437.1|1119800_1120244_+|hypothetical-protein
MRRDRIEGLWKHILLGYWIAAAFLFYFYAILMTIRMNGVIHEAFFHNPYVALGSLFPFLMLFQASILYFLEKRTIDISLLRIYLQFTVVQQVITGNLIGALLAFLYVRSLKRCGKKSTIYSKVLVLSSTIFIGTISLLAIFLLLRMS
>CP030110.1|AWX47436.1|1119032_1119800_+|MurR/RpiR-family-transcriptional-regulator
MELEKLIHQHAEKLSELDRGILNFILSDPSLIQNLKITDLAERLYVSKSSIMRTTKKLGFSGYSEFKYFLRHVTNKENGLRTKEDIFEKQLEDIQQTLHYMKAVNLKPILQCLDRSKMIYCYATGFSQKKVIDEFYKMMLGIGKRVMVLPNKTEFDMAMPLITLEDMAIIVSLSGETHEVKENLTAFELQKIPVLTITAAGDNYFTRHSTYHLNYYCNCFILGKENKPFQSLISLSCLADYLVRAYGVYTLREES
>CP030110.1|AWX47435.1|1117616_1118948_+|6-phospho-alpha-glucosidase
MKKFSITIAGGGSTFTPGIVLMLLKHLDRFPIRQIKFYDNLEERQTRIASACEILLKERAPDILFTATTDPETAFTDVDFVMAHIRVGLYAMREKDEKIPLKYGVVGQETCGPGGIAYGMRSIGGVLELIDYMEKYSPNAWMLNYSNPAAIVAEATRKLRPKAKIINICDMPVGIEERMAQAIGLASRKEMVVRYYGLNHFGWWTDIRDTEGNDLMPKIQEYVSQFGYALPSESQESQQTDASWKHTFMKAKEVYDIDPTTLPNTYLKYYFYPQDEVAHTNPEFTRANEVMVGREKQVFNECDRITSSGSAENTILEIDEHASYIVDLARAIAYNTHERMLLIVPNNGAIENFDESAMVEIPCIVGSNGPEPLIQGKIPRFQKGLMEQQVAVEKLVVEAWEERSYQKLWQALTLSKIVPNAKVAKNLLDDLVSVNQEYWPELK
>CP030110.1|AWX47434.1|1115982_1117572_+|PTS-alpha-glucoside-transporter-subunit-IIBC
MIMEKIQRFGGAMFTPVLLFSFSGIMVALCIIFKNPMLVGSIATEGTAWYSIWSVVESGAWTVFNQMELLFVIGLPIGLAKKASARAVMEAFVVYITCNYFISTMLGFYSGFFGVDFSADPGGASGLKMIAGIKTLDTGIIGAILISAVVVYLHNRFFDKKLPDFLGIYQGSSFVVIISFFIMLPIAFLICLIWPKIQSAISSLQGFLAGAGIFGVWLYTFLERILIPTGLHHFIYAPFAFGLAVVEEGIARYWMTHLQEFARSEQPLKHLFPEGGFALHGNSKIFASPGIAAAFYFTARPENRKKVLMILIPATLTAVLAGITEPLEFTFLFISPPLFAIHSLLAATMAAIMYGFGVVGDIGGGFIDLFVKVWIPLFQNHKGMIFTQLVIGLAFTGIYFIVFRYLIIKFDIATTGREENTDAVKLYTKKDYKEKERKTSKTEIENVYENQAAIYLEGFGGAGNIEKVTNCATRLRITVKNEMLVLEDTIFKEGGAHGVVRNGNAFQVIVGLDVPQVREQFERLLEIEQ
>CP030110.1|AWX47433.1|1115008_1115719_-|hypothetical-protein
MKKLGFILASISLFLVGCTSASKETSESSATAVKSSIRQTSSAEKSSTQKSASSESNTSSTTSKLSESNPSSISSGTVDTSLSSTADTSFSQSSQSVDPLAGYSDLQIEYARVWLAVKGNTFKDASGDFELHVIHYPAGTPIDPYDAGSVGYPKDVVMLTGKYGYQGILVYSSNHDGTITSYPVPSHWQIPADQASDPAFIKKTTQEIIDHASVVAIPTGNPNDVKQLIDVTVIDN
>CP030110.1|AWX47432.1|1113882_1114893_+|LD-carboxypeptidase
MIRYPLLGKNTTIGVIAPSSGVAEEHHLLLEMALKSMEEKSFHVVTGKTLWTQDKEKSAPARERADEFNQMMKDENIQMIFPPWGGELLIEILDSVDFDALQPKWIVGYSDISTLLLAITLKTGIATAHGTNLIDLRGNYSDKTTAMWKSVLETGKGESILQRSSEKYQKEWHHEQPSPSVFHLTEPTNWQTVSGEAVRIKGRLLGGCIDTIRHLIGTPYGDVQTFKRTYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFEDSSGIMFGRSAAEDLLDYRMKDVYEDLSKELNIPILYDIDCGHVPPQLTLINGAYAEVSVKDGKETILQTFI
>CP030110.1|AWX47431.1|1113364_1113859_+|prolyl-tRNA-editing-protein
MIDLAKKFSHANIYFELYHHRAIYTNEDALVVKKEQGFTGTETKSLFLKDKKDNNYVYLTFTTKQTDFKALGKIIGKRLSIVSSEHMEEQTGQKQGAVSPFGYEEQIPIIIDEELLSKEKLVFAPGRPDQTMVIKTFDLNKIIQLLKIPMFLMPANENNNNQTK
>CP030110.1|AWX47430.1|1112846_1113215_-|iron-chaperone
MEKFRLIIDQIKEKENQQKINDLFSKIAKTYPQLDTTVKWNQPIFTDHGTFIIAFSFAENHFSIAPEKAAIRALEKTIQEIGYIYTDNVIKVPWKSAINWELIDHFISFNIEDKKDHNKFWR
>CP030110.1|AWX47440.1|1123878_1125156_+|hypothetical-protein
MKKKVHWGVVGATIIVAGGMAVFTINEQNYSRQVEAVASELSTHKKQLQKIETEIAGLYADEHKQFLSSDVTQAKIDSLKKTIEKFKSEAESHAKKVETLRKQDQETCQKELVDITKLDEKINEVQMIFDQTQAVNSLFSTPYIENAEINEEAIIIDDLNSEMIEEKKEKIELENLEENEFSSAISKAIKSAENQLAQIERARKVVEELYKDGKPTDKVTRETLESVKKEVELIKNEKAKKSFNEPLKAIEEKVTADEKAEAERVAAEEAKRQEEQASENQATQQTEVPETQSATTDPVDTPTTPNRPVQNVTENITVQPTTPVAPPTNSGSGSNTGGTTSTPGSNTSGGSTGGGMTPAPTPTPTPEAPYALNPYRGSGTMYTSNSSAIAAGENWILTSPNSSGGYNIIDEYWSDGSVRYYLELY
>CP030110.1|AWX47441.1|1125279_1128363_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKKYQIKLRIWLMLGILFGSFLSQPMTALAITNNQEQSEKTESVQNEQENEPDIVEQFLQKNNLIRGEDGKLYTTTPSTYVNESIHDILSGNQLTKAANQVVYVDPSTNVANIDIHLSNGSREYGWYGKRVNGQIALCIEQGVAVNVGSNGGYTAVLQDTELMKRISLIKYYGIILPGHTLQREIMTQILAYEQQGIYPTSISGVFSMADYQAFKSNVMANVNKFYTKPSFDGRTVTLKVGESITLNDTTGAFSNYESNAVVNTSNVLIEKNGNMVKITATKESNQSGMVRFRYNIPANYAGTPVIYNHPYTQNVLLGRVRDPSFVTFNINVLKNGNARIRKVDETTKQPLAGAVFRFTTSDGQSREITTGSDGYATWNDLLVDTRVTIQEIKAPNGYILNSTPQTITIRANETTTVTMDNKEQLANLTVIKEDEETGNTPQGAAQLIGAVYELTDGNGASVAKLTMEDVNGVAQAELKGLKLGTYYLQEIEPPKGYNLDPTKYTVQLTYAGQNETVAIHRKTVTDRVIKGHIEGYKLGSRPLIPQTITEILNQISNKNQDIKPPLEGVELTATSHTTGQEYVQVTGKNGYFRFENLPYDTYTIEETKGVDGYLLIEPFEVTITEEGYTHFFLLEDKIIESRLHIVKVDEETGENIPYAGAQFKIFDTWANDGEGAFVSMQRPNDTESTDIFETNEKGEIVTTESLAWGIDRYELHEIKAPEGYVPLEEPLVFSVTEEDAGALIRLEVPNRLARQNIQLIKRDRLNEQPLANVPFNLFKLETDEAGESTEVLLDEYLTDETGEINIEGLPYGEYKFVEGEPLEGYLPLEDALEFSVTVEKDGELIVLEAFNERKQLELMSLFTDVNGKKELDPTVDHRLKDTVWVKGAAIEVGHTYTVFTQYKNTKTGEVVSEATSTYTAKSKEDEFDVFLDLKANTVKDGDQLTATHVLYYEEEQLNEVAREDDLTNKDQTVSFKTPEQPKENKSETPKKQTTLPKTGSVHTILGVVLGGLLVTLVVFVWLSRAKK
>CP030110.1|AWX47442.1|1128483_1129467_+|conjugal-transfer-protein
MKLKTIKKKEKKEKKPKVKKLSQKRANKIVFTGMSLLMIASAVGVIRANVVATNFDNLTDKVDQLAKSKNEKSIQKEVFDYSALSFYATSFAEEYLNYDASANEEEKKERLDRLEKYLSVDVDAVDETSKSQKEFIRRFKSAAVVQIKEESECLLVSLNVIYETEKEEEKKTLTQEMVLPIQTKNQLFSIVGRPYFLATTLPQGKTTELKQAEASLDVPPQEKEAIEKFLTLFFEKYANGEKQELMLLMKEPVQTSGVTEFISLNENEIKYFETKQKEVKGIQVSVTFADKQTGMTHTEDFSLWLTQTENSYFVRTLKHYFTEKEGN
>CP030110.1|AWX47443.1|1129470_1129695_+|hypothetical-protein
MNVSNLDNFMRTGFITLLSFAVILLIFKHWRGAEWLKIGSVILIALILNDFATNQGRNIFNLVKWFLGLFGITM
>CP030110.1|AWX47444.1|1129704_1130094_+|conjugal-transfer-protein
MKHYDYSRGLKAPYSIQVISSPKGKALWVFAQPLNMSYLLMLFFLLFVTGVFWYKVRIPNIAGINLNLLLMLSVPHKVARWYSEAELDGKSTNLFLKDFIVYLKNFVMDQRPIIAFERVDQLEEFSFKR
>CP030110.1|AWX47445.1|1130113_1132618_+|conjugal-transfer-protein
MQLEYPLSEYMHENMLLTQEKTAIAYYRIRSETVMLTDFEKKQKTKKKVARALKRLKGSGGFEINLLPVNADIRGKMGAMRSLIDPENHAVGVDKLMKTAQILENEMGMVYEYAWIIGVPLVKKEIAIDLKENISKAVNHVTETIVKGLGFDVALEKEWAKDYQEQEQEIYQNLSELLIERLTEDELYYYQAYQFLKNIPHERQDVLASQTFENLMETKIQPIFSGGLHFQCDYGESYVSYLPVGDIGVFLDGNHLLEIVQKMPFPVEVKIQASFAESKGQLALSGRSARARTRTKNIMQEAHLAGSKQKRKIVEGQLSLDDLDQKIDDGVDILDWKAVLVVSGSTKKQLQARKKYLINRFDGLGIPLLKATFDDPYLFQSTLFGNFLRMKDKKWQHTSTIESFAELNFFTSLKAGTNLGYYFGRVDTTLEEKEDRKSILLNSKNLIYMNLFLANKQDIVGKKTNNPHWALTGDTGNGKSVTAKKLFMECATLKDRVLYIDPKKEMRRQFMRTINDPAYQKKYPLDTAFVRSFNFVTLDVRDKKNLGVLDPIVLFDETEAIATAKAMLTNIYEGIWNLKQKTEINETIAAIVKERKSGKKVGFWQVVEKLASSSIPDVQDMGRFLISTIKGSILELAFSHGEVPGLSFEKKVTILEIEDLDLPTDKNEHMDENKRLSVTLMFALGTFCSKFGSRNPKQETVTFFDESWIFQSSPEGKAILKSMKRIGRSFNNFLVLITQSVNDLDDKEDGTGFGTVICFDEVQNREGILQYLNLPINEQNMKWVSNMVQGQCLLKDMFNQVNRVVVHVLFEEWLELFKTVDDSDASVMENHFAV
>CP030110.1|AWX47446.1|1132632_1134594_+|hypothetical-protein
MKFLIDSYDAYMVGGGLLDKGWQVVNWFFVGLPFFFLKLCVSFFLFCESVLNQSDYFIAKQAEMFDMSVQILRNFGGTGFGRGTLMGLAIMLSAYYLLYHFFSNRHNFSQSLLHYVVVLLLFFGWFGQITTRQGTYNTSSFFIQSVNSIVKTVQNQFISGTNYGSDSDQSPMFDATVKQTFYFVNSGSLDGTMENGEKLDEAKLLQVPNLSKEEKETFKKDREQYIDSLENENPYFAQDGSKTMEKSFAIWVGVANLFILALPVLYINMMLTIIQILVNLLILAFPILALASFFPRCQMLMFKFFKTLIGILFMPVIYGVFISVLFWVNQLIDQVFLHAAQGINENLLNVLSGSILLLGTRLIMVLVKIVFISTVWKNRYRILGFFADGQIQQPIFEKKVNEKTKEGAEQISGASIGAAQLAAGAYTGNPNIALNGLSKILPDKAMTLGKEHFLDEENQFTGVKQGLGSLFRPSDYDDTELSIPEEDKMEMDQVDQQVEDEVLVDEEVDDKALEDVLAEINEADPTFDQSLSESDALISDDVLMSDLSDSDLTNDTEALFEQDEVAMSENEIPIDPTVLSEKMNVTVDNFDELQLSQEEQAYFDHAYDPELIANYSSEVEPIHQIEENFKSLESEETFFDAWEEEQKEPMEDW
>CP030110.1|AWX47447.1|1134651_1135686_+|CHAP-domain-containing-protein
MKKIAYIILGTCFAFLLPFLLFIGIFSANQNGSTSEFEPGTPQEQVALEVAQYVQQKGGTKEFAAAWIGNMEHESGLIPSRIQSDLAFNPVWAYNPDIGGYAMGLAQWDSSRRVNMLNLAREQNEDWKAVAFQMDFAWYHDGSDSDLLKNMSNGTEIEKLAVDILKYWERAGTKDDPVEQNKRKTSAVNWYKRLFEGSLGGGSANIGGDKIDILESVMGQTINGGQCYGLTAYYVQKLGGPQMMGSGFMYAQSIGSDYDWQKYGWAVIFDPKPSEIKAGDVINWYAGEALSPGIYGHTGIIASVESEGKFITYEQNAEQGQICAKYARQWGREFNRVASVVRKK
>CP030110.1|AWX47448.1|1135700_1135928_+|hypothetical-protein
MFFTHPGLTRRQVKEICAKFQCSQNEFVARRFEDGFLVSLRNKEYRVKFSPGRFSQIVFVKEVVRVTANRKQGRG
>CP030110.1|AWX47449.1|1135924_1136464_+|hypothetical-protein
MKRILFLIGTTLSVLTLVACSSPDEQAETTESVKDSSIMEAVENSSLKLENAKAESSQPTATQEIVEEDREENPIEDHMELLQAYGEAYANFKTINHRNEKLKDLMTEECIQMNGIDVETGNALGSEGKVTSIYQNNQDEYAVLLDCIQNGSPIRILLLAKVEDNKIAEMTYNTLKREY

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP030110_1	1.1\|334560\|30\|CP030110\|PILER-CR,CRISPRCasFinder,CRT	334560-334589	30	CP030110.1	931161-931190	0	1.0

1. spacer 1.1|334560|30|CP030110|PILER-CR,CRISPRCasFinder,CRT matches to position: 931161-931190, mismatch: 0, identity: 1.0

tttaccgattgccaacacttctaatccaaa	CRISPR spacer
tttaccgattgccaacacttctaatccaaa	Protospacer
******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP030110_1	1.6\|334890\|30\|CP030110\|PILER-CR,CRISPRCasFinder,CRT	334890-334919	30	NC_011245	Borrelia duttonii Ly plasmid pl28, complete sequence	23714-23743	5	0.833
CP030110_1	1.6\|334890\|30\|CP030110\|PILER-CR,CRISPRCasFinder,CRT	334890-334919	30	MN693212	Marine virus AFVG_25M426, complete genome	7433-7462	6	0.8
CP030110_1	1.4\|334758\|30\|CP030110\|PILER-CR,CRISPRCasFinder,CRT	334758-334787	30	MG592515	Vibrio phage 1.144.O._10N.286.45.B3, partial genome	27153-27182	7	0.767
CP030110_1	1.6\|334890\|30\|CP030110\|PILER-CR,CRISPRCasFinder,CRT	334890-334919	30	NC_014023	Bacillus megaterium QM B1551 plasmid pBM700, complete sequence	73613-73642	8	0.733
CP030110_1	1.6\|334890\|30\|CP030110\|PILER-CR,CRISPRCasFinder,CRT	334890-334919	30	NC_014025	Bacillus megaterium QM B1551 plasmid pBM500, complete sequence	20379-20408	8	0.733

1. spacer 1.6|334890|30|CP030110|PILER-CR,CRISPRCasFinder,CRT matches to NC_011245 (Borrelia duttonii Ly plasmid pl28, complete sequence) position: , mismatch: 5, identity: 0.833

cttttcctaataatttacaatc-atcaatat	CRISPR spacer
attttactaataatttacaatctggcaata-	Protospacer
 **** **************** . *****

2. spacer 1.6|334890|30|CP030110|PILER-CR,CRISPRCasFinder,CRT matches to MN693212 (Marine virus AFVG_25M426, complete genome) position: , mismatch: 6, identity: 0.8

cttttcctaataatttacaatcatcaatat	CRISPR spacer
cttttgctaataatttacaatgttgtaaat	Protospacer
***** ***************  *  * **

3. spacer 1.4|334758|30|CP030110|PILER-CR,CRISPRCasFinder,CRT matches to MG592515 (Vibrio phage 1.144.O._10N.286.45.B3, partial genome) position: , mismatch: 7, identity: 0.767

cttatatgacagcttataaagtgttatgta	CRISPR spacer
ctctgatgacagattataaactgttatgct	Protospacer
**.  ******* ******* *******.

4. spacer 1.6|334890|30|CP030110|PILER-CR,CRISPRCasFinder,CRT matches to NC_014023 (Bacillus megaterium QM B1551 plasmid pBM700, complete sequence) position: , mismatch: 8, identity: 0.733

cttttcctaataatttacaatcatcaatat	CRISPR spacer
attttcctaataattgagaatcatttccct	Protospacer
 ************** * ******.  . *

5. spacer 1.6|334890|30|CP030110|PILER-CR,CRISPRCasFinder,CRT matches to NC_014025 (Bacillus megaterium QM B1551 plasmid pBM500, complete sequence) position: , mismatch: 8, identity: 0.733

cttttcctaataatttacaatcatcaatat	CRISPR spacer
attttcctaataattgagaatcattttcct	Protospacer
 ************** * ******.  . *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

981292 : 1065014

Enterococcus_phage(20.93%)

head,tail,protease,portal,integrase,capsid,tRNA,terminase,holin

attL 988719:988740|attR 1032855:1032876

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWX47293.1\|981292_982054_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
AWX47294.1\|982189_982537_+	50S ribosomal protein L19	NA	NA	NA	NA
AWX47295.1\|982797_983091_+	DUF2087 domain-containing protein	NA	NA	NA	NA
AWX47296.1\|983380_985045_+	acetolactate synthase AlsS	NA	NA	NA	NA
AWX47297.1\|985057_985768_+	acetolactate decarboxylase	NA	NA	NA	NA
AWX47298.1\|985896_986394_+	GAF domain-containing protein	NA	NA	NA	NA
AWX47299.1\|986578_986839_+	hypothetical protein	NA	NA	NA	NA
AWX47300.1\|987251_987788_-	VanZ family protein	NA	NA	NA	NA
988719:988740	attL	NA	NA	NA	NA
AWX47301.1\|988745_989888_-\|integrase	site-specific integrase	M1PRU8	Streptococcus_phage	6.3e-57	36.9
AWX47302.1\|989994_990951_-	Abi family protein	X2L062	Streptococcus_phage	1.6e-82	48.6
AWX47303.1\|991141_991348_-	DUF4177 domain-containing protein	NA	NA	NA	NA
AWX48841.1\|991371_991473_-	LysM domain-containing protein	NA	NA	NA	NA
AWX47304.1\|991744_992746_-	Abi family protein	A0A2H4JB40	uncultured_Caudovirales_phage	4.1e-28	26.7
AWX47305.1\|992857_993277_-	hypothetical protein	NA	NA	NA	NA
AWX47306.1\|993409_994063_-	hypothetical protein	NA	NA	NA	NA
AWX47307.1\|994112_994541_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
AWX47308.1\|994545_994920_-	XRE family transcriptional regulator	A0A2P0ZLA1	Lactobacillus_phage	1.4e-21	45.5
AWX47309.1\|995204_995390_+	XRE family transcriptional regulator	Q5YAA3	Bacillus_phage	3.8e-12	58.3
AWX47310.1\|995403_995652_+	hypothetical protein	NA	NA	NA	NA
AWX47311.1\|995859_996642_-	hypothetical protein	NA	NA	NA	NA
AWX47312.1\|996694_997402_+	phage regulatory protein	D2IYT0	Enterococcus_phage	2.0e-69	56.5
AWX47313.1\|997577_997919_+	hypothetical protein	NA	NA	NA	NA
AWX47314.1\|997911_998643_+	DUF1071 domain-containing protein	A0A2I7RDU5	Vibrio_phage	1.2e-45	53.6
AWX47315.1\|998648_999335_+	hypothetical protein	C9E2N1	Enterococcus_phage	4.9e-89	70.0
AWX47316.1\|999338_1000085_+	helix-turn-helix domain-containing protein	F8J194	Lactobacillus_virus	3.3e-30	58.8
AWX47317.1\|1000096_1000366_+	hypothetical protein	NA	NA	NA	NA
AWX47318.1\|1000527_1000830_+	hypothetical protein	NA	NA	NA	NA
AWX47319.1\|1000826_1000988_+	antitoxin	NA	NA	NA	NA
AWX47320.1\|1000984_1001296_+	hypothetical protein	NA	NA	NA	NA
AWX47321.1\|1001398_1001929_+	hypothetical protein	A0A0S2MYJ7	Enterococcus_phage	3.7e-52	59.3
AWX47322.1\|1002098_1002716_+	DUF1642 domain-containing protein	A0A141E1K4	Streptococcus_phage	5.1e-13	34.9
AWX47323.1\|1002712_1003009_+	hypothetical protein	NA	NA	NA	NA
AWX47324.1\|1003084_1003501_+	autolysin	C9E2P5	Enterococcus_phage	1.4e-46	67.4
AWX47325.1\|1003776_1004415_+	hypothetical protein	NA	NA	NA	NA
AWX47326.1\|1004899_1005085_+	hypothetical protein	F0PII8	Enterococcus_phage	5.8e-21	82.0
AWX47327.1\|1005077_1005341_+	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	1.6e-32	74.7
AWX47328.1\|1005381_1005609_+	hypothetical protein	NA	NA	NA	NA
AWX47329.1\|1005605_1005893_+	hypothetical protein	NA	NA	NA	NA
AWX47330.1\|1006422_1006737_+	HNH endonuclease	A0A0K2CYS9	Paenibacillus_phage	5.2e-14	43.8
AWX47331.1\|1006720_1006939_+	hypothetical protein	NA	NA	NA	NA
AWX47332.1\|1007024_1007615_-	hypothetical protein	NA	NA	NA	NA
AWX47333.1\|1007666_1008122_+\|terminase	phage terminase small subunit P27 family	A6M947	Geobacillus_virus	3.1e-15	32.9
AWX47334.1\|1008112_1009903_+\|terminase	terminase large subunit	A0A1B1P7R3	Bacillus_phage	5.9e-195	55.8
AWX47335.1\|1009902_1011138_+\|portal	phage portal protein	A0A0U3SQF0	Bacillus_phage	5.6e-120	53.8
AWX47336.1\|1011172_1011898_+\|protease	Clp protease ClpP	A0A0B5A796	Paenibacillus_phage	3.7e-71	57.8
AWX47337.1\|1011898_1013035_+\|capsid	phage major capsid protein	A0A0C5AEH1	Paenibacillus_phage	4.8e-134	65.9
AWX47338.1\|1013108_1013471_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
AWX47339.1\|1013448_1013811_+\|head,tail	phage head-tail adapter protein	A0A059T6F2	Listeria_phage	9.0e-26	53.3
AWX47340.1\|1013803_1014208_+	hypothetical protein	A0A2H4J7V9	uncultured_Caudovirales_phage	9.1e-19	37.9
AWX47341.1\|1014204_1014615_+	hypothetical protein	A0A059T681	Listeria_phage	3.1e-22	47.2
AWX47342.1\|1014675_1015263_+\|tail	phage tail protein	A0A2P0ZLF5	Lactobacillus_phage	2.7e-35	41.0
AWX47343.1\|1015335_1015803_+	hypothetical protein	A5GYM0	Lactococcus_phage	1.6e-06	52.6
AWX47344.1\|1015848_1016157_+	hypothetical protein	NA	NA	NA	NA
AWX47345.1\|1016351_1022987_+\|tail	phage tail tape measure protein	M1PKM6	Streptococcus_phage	5.0e-130	42.2
AWX47346.1\|1022990_1023812_+\|tail	phage tail family protein	Q9T1A6	Listeria_phage	2.2e-56	44.6
AWX47347.1\|1023820_1024864_+	hypothetical protein	Q9T1A5	Listeria_phage	5.7e-105	54.4
AWX47348.1\|1024863_1025913_+	hypothetical protein	Q9T1A4	Listeria_phage	1.0e-21	31.9
AWX47349.1\|1025912_1028186_+	DUF2479 domain-containing protein	A0A0M4RT83	Enterococcus_phage	2.5e-65	42.1
AWX47350.1\|1028204_1028651_+	hypothetical protein	NA	NA	NA	NA
AWX47351.1\|1028652_1028790_+	XkdX family protein	NA	NA	NA	NA
AWX47352.1\|1028827_1029121_+	hypothetical protein	NA	NA	NA	NA
AWX47353.1\|1029143_1029341_+\|holin	holin	A0A0S2MYF6	Enterococcus_phage	8.6e-23	82.8
AWX47354.1\|1029351_1030371_+	N-acetylmuramoyl-L-alanine amidase	A0A1G5SA77	Enterococcus_phage	4.1e-60	66.1
AWX47355.1\|1030560_1031586_-	hypothetical protein	NA	NA	NA	NA
AWX47356.1\|1032450_1032753_-	hypothetical protein	NA	NA	NA	NA
AWX47357.1\|1033508_1034282_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
1032855:1032876	attR	NA	NA	NA	NA
AWX47358.1\|1034425_1034776_+	hypothetical protein	NA	NA	NA	NA
AWX47359.1\|1034756_1035473_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	6.1e-34	36.2
AWX47360.1\|1035472_1036921_+	sensor histidine kinase	A0A1V0SGX0	Hokovirus	6.0e-20	29.8
AWX47361.1\|1036993_1037503_-	hypothetical protein	NA	NA	NA	NA
AWX47362.1\|1037492_1038218_-	hypothetical protein	NA	NA	NA	NA
AWX47363.1\|1038389_1040510_-	LTA synthase family protein	W6LM83	Streptococcus_phage	7.5e-221	58.4
AWX47364.1\|1040738_1041917_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	6.0e-103	49.2
AWX47365.1\|1041932_1042685_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	1.3e-26	35.9
AWX47366.1\|1042707_1043193_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
AWX47367.1\|1043263_1044517_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	1.7e-23	55.3
AWX47368.1\|1044633_1045983_+	NADP-specific glutamate dehydrogenase	NA	NA	NA	NA
AWX47369.1\|1046094_1047441_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
AWX47370.1\|1047741_1048128_-	YxeA family protein	NA	NA	NA	NA
AWX47371.1\|1048993_1049206_+	hypothetical protein	NA	NA	NA	NA
AWX47372.1\|1049483_1051283_-	glycerophosphodiester phosphodiesterase	I6XE30	Staphylococcus_phage	6.3e-11	27.3
AWX47373.1\|1051409_1052006_-	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	4.3e-33	41.1
AWX47374.1\|1052376_1052721_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
AWX47375.1\|1052721_1053141_+	cupin domain-containing protein	NA	NA	NA	NA
AWX47376.1\|1053230_1053584_-	hypothetical protein	NA	NA	NA	NA
AWX47377.1\|1053549_1054881_-	DUF1576 domain-containing protein	NA	NA	NA	NA
AWX47378.1\|1055136_1055703_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AWX47379.1\|1056224_1058120_+	asparagine synthase (glutamine-hydrolyzing)	F2Y2L7	Organic_Lake_phycodnavirus	3.5e-20	26.2
AWX47380.1\|1058201_1058648_-	DUF2188 domain-containing protein	NA	NA	NA	NA
AWX47381.1\|1058875_1059025_+	50S ribosomal protein L33	NA	NA	NA	NA
AWX47382.1\|1059112_1059631_+	dihydrofolate reductase	G3MBI7	Bacillus_virus	5.4e-24	39.1
AWX47383.1\|1059704_1060661_-	ferrichrome ABC transporter substrate-binding protein	NA	NA	NA	NA
AWX47384.1\|1060826_1061633_+	ABC transporter ATP-binding protein	A0A1V0SJ29	Klosneuvirus	7.9e-14	30.0
AWX47385.1\|1061629_1062619_+	iron ABC transporter permease	NA	NA	NA	NA
AWX47386.1\|1062615_1063620_+	iron ABC transporter permease	NA	NA	NA	NA
AWX47387.1\|1063753_1064296_+	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
AWX47388.1\|1064315_1065014_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA

DBSCAN-SWA_2

1596797 : 1605836

Synechococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWX47859.1\|1596797_1597376_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.3e-26	36.9
AWX48862.1\|1597372_1598416_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	2.9e-61	43.9
AWX47860.1\|1598447_1599887_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.8e-53	33.3
AWX47861.1\|1599871_1602094_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.6e-152	41.6
AWX47862.1\|1602094_1602766_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AWX47863.1\|1602767_1603022_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AWX47864.1\|1603021_1603750_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	1.1e-41	40.9
AWX47865.1\|1604005_1604383_+	hypothetical protein	NA	NA	NA	NA
AWX47866.1\|1604540_1605836_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.0e-18	33.1

DBSCAN-SWA_3

2009894 : 2018366

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWX48238.1\|2009894_2012084_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	6.8e-286	66.7
AWX48239.1\|2012398_2013001_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A288TZV3	Enterococcus_phage	4.9e-53	58.0
AWX48240.1\|2013054_2014176_-	DNA polymerase IV	NA	NA	NA	NA
AWX48241.1\|2014284_2015157_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	9.6e-90	60.4
AWX48242.1\|2015225_2015573_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	5.1e-18	41.1
AWX48243.1\|2015565_2016390_-	signal peptidase	NA	NA	NA	NA
AWX48244.1\|2016425_2017364_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.3e-33	33.4
AWX48245.1\|2017377_2017707_-	hypothetical protein	NA	NA	NA	NA
AWX48246.1\|2017721_2018366_-	dTMP kinase	M1PSC7	Streptococcus_phage	4.2e-58	52.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP030110

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection