CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP019610	Mycobacterium tuberculosis strain H54 chromosome, complete genome	0 crisprs	cas4,WYL,csa3,DinG,cas3,c2c9_V-U4,DEDDh,cas6,cas10,csm2gr11,csm3gr7,csm4gr5	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1367154 : 1379957

uncultured_Caudovirales_phage(25.0%)

protease,transposase,integrase

attL 1359261:1359277|attR 1384424:1384440

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1359261:1359277	attL	NA	NA	NA	NA
AWY72165.1\|1367154_1367349_-\|integrase	integrase	A0A2H4JG32	uncultured_Caudovirales_phage	3.8e-07	54.5
AWY72166.1\|1367285_1367600_-\|integrase	integrase	Q854H9	Mycobacterium_phage	1.0e-09	53.6
AWY72167.1\|1367623_1367962_-\|integrase	integrase	NA	NA	NA	NA
AWY72168.1\|1368657_1368861_-	hypothetical protein	NA	NA	NA	NA
AWY74825.1\|1368906_1369533_+	hypothetical protein	NA	NA	NA	NA
AWY72169.1\|1369827_1370583_+	hypothetical protein	NA	NA	NA	NA
AWY74826.1\|1370741_1371647_-	oxidoreductase	NA	NA	NA	NA
AWY72170.1\|1371695_1372142_-	MarR family transcriptional regulator	NA	NA	NA	NA
AWY72171.1\|1372214_1372418_+	hypothetical protein	NA	NA	NA	NA
AWY72172.1\|1372374_1373490_+	hypothetical protein	NA	NA	NA	NA
AWY72173.1\|1373857_1375105_-\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	3.1e-81	45.1
AWY72174.1\|1375104_1375893_+	hypothetical protein	NA	NA	NA	NA
AWY72175.1\|1376851_1377475_-	hypothetical protein	NA	NA	NA	NA
AWY74827.1\|1377721_1378747_+\|protease	serine protease	NA	NA	NA	NA
AWY72176.1\|1379093_1379957_+\|transposase	IS5 family transposase	A0A1V0SLQ8	Klosneuvirus	8.5e-06	28.7
1384424:1384440	attR	NA	NA	NA	NA

DBSCAN-SWA_2

3075533 : 3110497

Mycobacterium_phage(25.0%)

tRNA,protease,transposase,integrase

attL 3107153:3107174|attR 3112576:3112597

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWY73565.1\|3075533_3076427_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
AWY73566.1\|3076388_3078074_-	hypothetical protein	NA	NA	NA	NA
AWY73567.1\|3078048_3078288_-	hypothetical protein	NA	NA	NA	NA
AWY75016.1\|3078345_3079026_-	cutinase family protein	NA	NA	NA	NA
AWY73568.1\|3079072_3079861_-	cutinase	NA	NA	NA	NA
AWY73569.1\|3079981_3081394_+	type VII secretion protein EccB	NA	NA	NA	NA
AWY75017.1\|3081358_3082726_-\|protease	type VII secretion-associated serine protease	NA	NA	NA	NA
AWY73570.1\|3082722_3084126_-	type VII secretion integral membrane protein EccD	NA	NA	NA	NA
AWY73571.1\|3084239_3087950_+	type VII secretion protein EccC	V5UPA0	Mycobacterium_phage	2.7e-77	27.1
AWY73572.1\|3087946_3089161_+	type VII secretion-associated protein	NA	NA	NA	NA
AWY73573.1\|3089213_3089531_+	type VII secretion protein EsxU	NA	NA	NA	NA
AWY73574.1\|3089551_3089854_+	WXG100 family type VII secretion target	NA	NA	NA	NA
AWY75018.1\|3090086_3090530_+	50S ribosomal protein L13	NA	NA	NA	NA
AWY73575.1\|3090526_3090982_+	30S ribosomal protein S9	NA	NA	NA	NA
AWY73576.1\|3091106_3092453_+	phosphoglucosamine mutase	NA	NA	NA	NA
AWY73577.1\|3092500_3092812_+	hypothetical protein	NA	NA	NA	NA
AWY75019.1\|3092814_3094218_+	hypothetical protein	NA	NA	NA	NA
AWY73578.1\|3094237_3095080_-	alpha/beta hydrolase	NA	NA	NA	NA
AWY73579.1\|3095089_3095566_-	hypothetical protein	NA	NA	NA	NA
AWY73580.1\|3095587_3097462_+	glutamine--fructose-6-phosphate aminotransferase	Q84421	Paramecium_bursaria_Chlorella_virus	4.6e-97	36.1
AWY73581.1\|3097683_3098538_+	DUF4436 domain-containing protein	NA	NA	NA	NA
AWY73582.1\|3098548_3099262_+	hypothetical protein	NA	NA	NA	NA
AWY73583.1\|3099263_3100685_+	bifunctional ADP-dependent (S)-NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase	NA	NA	NA	NA
AWY73584.1\|3100722_3102105_+	glutamate decarboxylase	NA	NA	NA	NA
AWY73585.1\|3102337_3103183_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	2.7e-73	53.2
AWY73586.1\|3103477_3103633_+	hypothetical protein	NA	NA	NA	NA
AWY73587.1\|3103671_3104835_+\|transposase	transposase	U5P429	Shigella_phage	3.2e-08	27.6
AWY73588.1\|3104775_3105312_-	PPE family protein	NA	NA	NA	NA
AWY73589.1\|3105474_3105837_+	hypothetical protein	NA	NA	NA	NA
AWY75020.1\|3106304_3106571_+\|transposase	transposase	NA	NA	NA	NA
AWY73590.1\|3106719_3107115_-	hypothetical protein	NA	NA	NA	NA
3107153:3107174	attL	NA	NA	NA	NA
AWY73591.1\|3107205_3107748_-	PPE family protein	NA	NA	NA	NA
AWY75021.1\|3107833_3108133_-	PE family protein	NA	NA	NA	NA
AWY73592.1\|3108648_3108846_+\|integrase	integrase	NA	NA	NA	NA
AWY73593.1\|3108928_3110497_+\|transposase	transposase	NA	NA	NA	NA
3112576:3112597	attR	NA	NA	NA	NA

DBSCAN-SWA_3

3155410 : 3203119

Burkholderia_virus(25.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWY75027.1\|3155410_3156088_-\|transposase	transposase	NA	NA	NA	NA
AWY75028.1\|3156077_3156782_-\|transposase	transposase	NA	NA	NA	NA
AWY73635.1\|3156930_3157239_+	antitoxin VapB46	NA	NA	NA	NA
AWY73636.1\|3157238_3157631_+	ribonuclease VapC46	NA	NA	NA	NA
AWY73637.1\|3158384_3159065_+	polyprenyl synthetase	NA	NA	NA	NA
AWY75031.1\|3159091_3159928_-\|transposase	transposase	Q8W6R2	Burkholderia_virus	2.9e-83	59.0
AWY73638.1\|3160026_3160353_-	hypothetical protein	A0A1B3AZF8	Gordonia_phage	4.4e-16	46.1
AWY75030.1\|3160794_3161784_+	4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2	NA	NA	NA	NA
AWY75029.1\|3161813_3163619_+	1-deoxy-D-xylulose-5-phosphate synthase	NA	NA	NA	NA
AWY73639.1\|3163627_3164518_+	diterpene synthase	NA	NA	NA	NA
AWY73640.1\|3164522_3166028_+	cyclase	NA	NA	NA	NA
AWY75032.1\|3166066_3166720_-	haloacid dehalogenase	NA	NA	NA	NA
AWY73641.1\|3166827_3168255_-	amidase	NA	NA	NA	NA
AWY73642.1\|3168259_3168508_-	enoyl-CoA hydratase	NA	NA	NA	NA
AWY73643.1\|3168508_3169150_-	enoyl-CoA hydratase	NA	NA	NA	NA
AWY73644.1\|3169228_3169333_-	PE family protein	NA	NA	NA	NA
AWY73645.1\|3169386_3170562_-	trehalose-phosphatase	NA	NA	NA	NA
AWY73646.1\|3170603_3171944_-	wax ester/triacylglycerol synthase family O-acyltransferase	NA	NA	NA	NA
AWY73647.1\|3172135_3175375_+	error-prone DNA polymerase	A0A1C9LWS4	Streptomyces_phage	1.6e-118	32.4
AWY73648.1\|3175463_3175898_-	PPOX class F420-dependent oxidoreductase	NA	NA	NA	NA
AWY73649.1\|3175896_3176541_+	oxidoreductase	NA	NA	NA	NA
AWY75033.1\|3176541_3178317_-	PE family protein	NA	NA	NA	NA
AWY73650.1\|3178683_3179148_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
AWY73651.1\|3179383_3182014_+	ATP-binding protein	NA	NA	NA	NA
AWY73652.1\|3182010_3182403_+	dynein regulation protein LC7	NA	NA	NA	NA
AWY73653.1\|3182380_3182749_+	hypothetical protein	NA	NA	NA	NA
AWY73654.1\|3182729_3183311_+	ATP/GTP-binding protein	NA	NA	NA	NA
AWY73655.1\|3183317_3183869_+	pentapeptide repeat protein MfpA	NA	NA	NA	NA
AWY73656.1\|3183865_3184234_-	hypothetical protein	NA	NA	NA	NA
AWY73657.1\|3184350_3185541_-	oxidoreductase	NA	NA	NA	NA
AWY73658.1\|3185582_3185840_-	toxin YoeB	NA	NA	NA	NA
AWY73659.1\|3185836_3186112_-	antitoxin	NA	NA	NA	NA
AWY73660.1\|3186235_3187081_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	NA	NA	NA	NA
AWY73661.1\|3187077_3187371_+	hypothetical protein	NA	NA	NA	NA
AWY73662.1\|3187384_3187774_-	hypothetical protein	NA	NA	NA	NA
AWY73663.1\|3187888_3188149_+	oxidoreductase	NA	NA	NA	NA
AWY73664.1\|3188291_3188663_+	oxidoreductase	A0A0B5JBT9	Pandoravirus	3.3e-15	56.4
AWY73665.1\|3188744_3189539_+	oxidoreductase	NA	NA	NA	NA
AWY73666.1\|3189782_3195983_+	PPE family protein	NA	NA	NA	NA
AWY73667.1\|3195877_3200932_+	hypothetical protein	NA	NA	NA	NA
AWY73668.1\|3201319_3201556_+\|transposase	transposase	NA	NA	NA	NA
AWY75034.1\|3201850_3202591_+\|transposase	transposase	NA	NA	NA	NA
AWY73669.1\|3202627_3203119_-\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

3817754 : 3865606

Burkholderia_virus(25.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWY74151.1\|3817754_3819503_+\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
AWY74152.1\|3819503_3819992_-	hypothetical protein	NA	NA	NA	NA
AWY74153.1\|3819988_3820534_-	hypothetical protein	NA	NA	NA	NA
AWY74154.1\|3820728_3821280_+	ribosome maturation factor RimP	NA	NA	NA	NA
AWY74155.1\|3821276_3822320_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
AWY74156.1\|3822446_3822746_+	hypothetical protein	NA	NA	NA	NA
AWY74157.1\|3822831_3825534_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.6e-21	23.1
AWY74158.1\|3825533_3826085_+	ribosome-binding factor A	NA	NA	NA	NA
AWY74159.1\|3826059_3827070_+	phosphoesterase	NA	NA	NA	NA
AWY74160.1\|3827076_3828396_+	DNA-damage-inducible protein DinF	NA	NA	NA	NA
AWY75105.1\|3828482_3829394_+	sn-glycerol-3-phosphate ABC transporter permease UgpA	NA	NA	NA	NA
AWY74161.1\|3829390_3830218_+	glycerol-3-phosphate ABC transporter permease	NA	NA	NA	NA
AWY74162.1\|3830220_3831531_+	sn-glycerol-3-phosphate ABC transporter substrate-binding lipoprotein UgpB	NA	NA	NA	NA
AWY74163.1\|3831523_3832606_+	sugar ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.9e-21	33.9
AWY74164.1\|3832684_3833434_-	enoyl-CoA hydratase	NA	NA	NA	NA
AWY75106.1\|3833480_3833696_+	prevent-host-death family protein	NA	NA	NA	NA
AWY74165.1\|3833692_3834085_+	ribonuclease VapC22	NA	NA	NA	NA
AWY74166.1\|3834105_3834375_+	hypothetical protein	NA	NA	NA	NA
AWY74167.1\|3834371_3834917_+	hypothetical protein	NA	NA	NA	NA
AWY75107.1\|3835221_3836109_+	hypothetical protein	NA	NA	NA	NA
AWY74168.1\|3836111_3836996_+	hypothetical protein	NA	NA	NA	NA
AWY75108.1\|3837267_3837813_+	hypothetical protein	NA	NA	NA	NA
AWY74169.1\|3837990_3838935_+	CRISPR-associated endoribonuclease Cas6	NA	NA	NA	NA
AWY74170.1\|3838931_3841370_+	type III-A CRISPR-associated protein Cas10/Csm1	NA	NA	NA	NA
AWY74171.1\|3841366_3841741_+	type III-A CRISPR-associated protein Csm2	NA	NA	NA	NA
AWY74172.1\|3841750_3842461_+	CRISPR type III-associated RAMP protein Csm3	NA	NA	NA	NA
AWY74173.1\|3842441_3842798_+	type III-A CRISPR-associated RAMP protein Csm4	NA	NA	NA	NA
AWY75109.1\|3842824_3843661_-\|transposase	transposase	Q8W6R2	Burkholderia_virus	2.9e-83	59.0
AWY74174.1\|3843759_3844086_-	hypothetical protein	A0A1B3AZF8	Gordonia_phage	4.4e-16	46.1
AWY74175.1\|3845413_3846226_-	AAA family ATPase	NA	NA	NA	NA
AWY74176.1\|3846222_3847632_-\|transposase	transposase	NA	NA	NA	NA
AWY74177.1\|3847702_3848311_-	hypothetical protein	NA	NA	NA	NA
AWY74178.1\|3848730_3849042_-	hypothetical protein	NA	NA	NA	NA
AWY74179.1\|3849146_3849404_-	hypothetical protein	NA	NA	NA	NA
AWY74180.1\|3849736_3850063_+	hypothetical protein	A0A1B3AZF8	Gordonia_phage	4.4e-16	46.1
AWY75110.1\|3850161_3850998_+\|transposase	transposase	Q8W6R2	Burkholderia_virus	2.9e-83	59.0
AWY74181.1\|3851037_3852150_-\|transposase	transposase	NA	NA	NA	NA
AWY74182.1\|3852348_3852540_-	hypothetical protein	NA	NA	NA	NA
AWY75111.1\|3852536_3852941_-	hypothetical protein	NA	NA	NA	NA
AWY75112.1\|3853013_3853169_-	histone acetyltransferase	NA	NA	NA	NA
AWY75113.1\|3853151_3853343_+	hypothetical protein	NA	NA	NA	NA
AWY74183.1\|3853518_3853986_-	hypothetical protein	NA	NA	NA	NA
AWY74184.1\|3853984_3855028_+	hypothetical protein	NA	NA	NA	NA
AWY74185.1\|3855070_3855301_+	antitoxin MazE	NA	NA	NA	NA
AWY74186.1\|3855284_3855641_+	mRNA interferase MazF9	NA	NA	NA	NA
AWY74187.1\|3855742_3857392_-	hydrolase	NA	NA	NA	NA
AWY74188.1\|3857410_3858040_-	DUF3558 domain-containing protein	NA	NA	NA	NA
AWY74189.1\|3858170_3858497_+	hypothetical protein	NA	NA	NA	NA
AWY74190.1\|3858500_3860189_+	hypothetical protein	NA	NA	NA	NA
AWY74191.1\|3860188_3860752_+	hypothetical protein	NA	NA	NA	NA
AWY74192.1\|3860896_3861871_+	metallophosphoesterase	NA	NA	NA	NA
AWY74193.1\|3861867_3862551_+	4'-phosphopantetheinyl transferase	NA	NA	NA	NA
AWY74194.1\|3862547_3863444_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
AWY74195.1\|3863645_3864227_+\|transposase	IS607 family transposase	F9VHY9	Thermus_phage	5.0e-18	30.6
AWY74196.1\|3864226_3865606_+\|transposase	transposase	A0A7P9	Microcystis_virus	9.3e-31	30.3

DBSCAN-SWA_5

3982073 : 4013268

Mycobacterium_phage(30.0%)

protease,capsid,transposase,integrase

attL 3984950:3984977|attR 3994574:3994601

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWY74302.1\|3982073_3982877_-\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	3.5e-46	46.4
AWY74303.1\|3982876_3983368_+	hypothetical protein	NA	NA	NA	NA
AWY74304.1\|3983596_3983851_-	hypothetical protein	NA	NA	NA	NA
AWY74305.1\|3983861_3984095_-	hypothetical protein	NA	NA	NA	NA
AWY74306.1\|3984193_3984466_-	hypothetical protein	NA	NA	NA	NA
AWY74307.1\|3984371_3984761_+	hypothetical protein	NA	NA	NA	NA
AWY74308.1\|3984757_3984985_+	hypothetical protein	NA	NA	NA	NA
3984950:3984977	attL	NA	NA	NA	NA
AWY74309.1\|3985129_3986257_+\|integrase	integrase	A0A1X9SFC1	Mycobacterium_phage	1.5e-66	40.4
AWY75137.1\|3986259_3986622_+	hypothetical protein	NA	NA	NA	NA
AWY74310.1\|3986638_3986899_+	hypothetical protein	A0A2P1CHK7	Mycobacterium_phage	3.0e-15	64.6
AWY74311.1\|3986895_3987288_+	hypothetical protein	NA	NA	NA	NA
AWY74312.1\|3987289_3988717_+	hypothetical protein	NA	NA	NA	NA
AWY74313.1\|3988713_3988959_+	antitoxin	NA	NA	NA	NA
AWY75138.1\|3989038_3989362_+	toxin	NA	NA	NA	NA
AWY74314.1\|3989393_3990020_+	hypothetical protein	V9H0V4	Actinophage	1.6e-17	47.2
AWY75139.1\|3990172_3990706_+\|protease	prophage protease	A0A2H4JB68	uncultured_Caudovirales_phage	3.1e-06	32.9
AWY74315.1\|3990713_3992153_+\|capsid	major capsid protein	A0A1B3AYS4	Gordonia_phage	1.4e-66	40.6
AWY74316.1\|3992323_3992575_-	hypothetical protein	NA	NA	NA	NA
AWY74317.1\|3992562_3993027_-	hypothetical protein	NA	NA	NA	NA
AWY74318.1\|3993040_3994039_-\|integrase	integrase	A0A2D1G8E2	Mycobacterium_phage	7.4e-62	47.8
AWY74319.1\|3994035_3994467_-	hypothetical protein	NA	NA	NA	NA
AWY75140.1\|3995757_3995949_-	antitoxin MazE	NA	NA	NA	NA
3994574:3994601	attR	NA	NA	NA	NA
AWY74320.1\|3996183_3997680_-	arsenic-transport integral membrane protein ArsC	A0A2H4PQT9	Staphylococcus_phage	5.1e-14	39.7
AWY74321.1\|3997676_3998057_-	transcriptional regulator	NA	NA	NA	NA
AWY74322.1\|3998192_3998651_-	cadmium-induced protein CadI	NA	NA	NA	NA
AWY74323.1\|3998752_3999112_+	transcriptional regulator	NA	NA	NA	NA
AWY74324.1\|3999231_3999564_+	hypothetical protein	NA	NA	NA	NA
AWY74325.1\|3999738_4000185_-	anti-anti-sigma factor	NA	NA	NA	NA
AWY74326.1\|4000347_4001004_-	protein DedA	NA	NA	NA	NA
AWY74327.1\|4001199_4001877_-	hypothetical protein	NA	NA	NA	NA
AWY74328.1\|4001877_4002120_-	hypothetical protein	NA	NA	NA	NA
AWY74329.1\|4002148_4004485_+	PE family protein	NA	NA	NA	NA
AWY74330.1\|4004485_4004743_+	hypothetical protein	NA	NA	NA	NA
AWY74331.1\|4004769_4005255_+	hypothetical protein	NA	NA	NA	NA
AWY74332.1\|4005399_4005681_+	hypothetical protein	NA	NA	NA	NA
AWY74333.1\|4005719_4007018_-	RNA-splicing ligase RtcB	A2RQD0	Archaeal_BJ1_virus	3.8e-90	43.3
AWY74334.1\|4007157_4007697_-	archease	NA	NA	NA	NA
AWY74335.1\|4007698_4008823_-	hypothetical protein	NA	NA	NA	NA
AWY75141.1\|4009169_4009532_-	hypothetical protein	NA	NA	NA	NA
AWY74336.1\|4009841_4011083_+	alpha/beta hydrolase	NA	NA	NA	NA
AWY74337.1\|4011596_4012028_+	hypoxic response protein 1	A0A2I6B2H4	Macacine_betaherpesvirus	1.9e-75	100.0
AWY74338.1\|4012086_4013268_+\|protease	site-2 protease family protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage