CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP021771	Streptococcus agalactiae strain B507 chromosome, complete genome	2 crisprs	cas3,cas5,cas8c,cas7,cas4,cas1,cas2,cas9,csn2,csm6,DEDDh,WYL,csa3	0	10	5	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP021771_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021771_1

315631-316322

TypeI

I-C

Consensus_repeat	Method
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	PILER-CR
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	CRT

10 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of CP021771_1

>merge|CP021771|1|315631-316322|PILER-CR,CRISPRCasFinder,CRT
GTCGCACCCTTTGCGGGTGCGTGGATTGAAATATAGTCCCACATATTGCTATGAAAAAACGGAAAAGTCGCACCCTTTGCGGGTGCGTGGATTGAAATATAGTCCCACATATTGCTATGAAAAAACGGAAAAGTCGCACCCTTTGCGGGTGCGTGGATTGAAATTACTATATTTCCATTTATGTTCTGTCTGAAAAGACGTCGCACCCTTTGCGGGTGCGTGGATTGAAATTAAGTCTCGCTGTTACGCTTGACGCAGAGCAAACGTCGCACCCTTTGCGGGTGCGTGGATTGAAATTATTTTATATTAAAAATAAGACTACCATAATTATGTCGCACCCTTTGCGGGTGCGTGGATTGAAATAGGCAAAAGTCAACGAGCTACTCAAACAGCCAAAGTCGCACCCTTTGCGGGTGCGTGGATTGAAATGTCGTAAAGACGTAGCATATCACTAATTAGATCAGTCGCACCCTTTGCGGGTGCGTGGATTGAAATTAGCTGATAGCCTGCAATATACAACCATCCGTTTTGTCGCACCCTTTGCGGGTGCGTGGATTGAAATATCATATCTCTATAATTTCCTTTCATATCAACGCGTCGCACCCTTTGCGGGTGCGTGGATTGAAATTAATAATGATTATTTTTTTATTAATTCATTATCATCGCCCCTTTGCGGGTGTGTAGTTTCAACT

>CP021771|1|1|315631-316258|PILER-CR
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	ATAGTCCCACATATTGCTATGAAAAAACGGAAAA
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	ATAGTCCCACATATTGCTATGAAAAAACGGAAAA
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	TACTATATTTCCATTTATGTTCTGTCTGAAAAGAC
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	TAAGTCTCGCTGTTACGCTTGACGCAGAGCAAAC
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	TATTTTATATTAAAAATAAGACTACCATAATTAT
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	AGGCAAAAGTCAACGAGCTACTCAAACAGCCAAA
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	GTCGTAAAGACGTAGCATATCACTAATTAGATCA
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	TAGCTGATAGCCTGCAATATACAACCATCCGTTTT
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	ATCATATCTCTATAATTTCCTTTCATATCAACGC
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT

>CP021771|1|1|315631-316258|CRISPRCasFinder
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	ATAGTCCCACATATTGCTATGAAAAAACGGAAAA
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	ATAGTCCCACATATTGCTATGAAAAAACGGAAAA
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	TACTATATTTCCATTTATGTTCTGTCTGAAAAGAC
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	TAAGTCTCGCTGTTACGCTTGACGCAGAGCAAAC
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	TATTTTATATTAAAAATAAGACTACCATAATTAT
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	AGGCAAAAGTCAACGAGCTACTCAAACAGCCAAA
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	GTCGTAAAGACGTAGCATATCACTAATTAGATCA
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	TAGCTGATAGCCTGCAATATACAACCATCCGTTTT
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	ATCATATCTCTATAATTTCCTTTCATATCAACGC
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT

>CP021771|1|1|315631-316322|CRT
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	ATAGTCCCACATATTGCTATGAAAAAACGGAAAA
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	ATAGTCCCACATATTGCTATGAAAAAACGGAAAA
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	TACTATATTTCCATTTATGTTCTGTCTGAAAAGAC
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	TAAGTCTCGCTGTTACGCTTGACGCAGAGCAAAC
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	TATTTTATATTAAAAATAAGACTACCATAATTAT
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	AGGCAAAAGTCAACGAGCTACTCAAACAGCCAAA
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	GTCGTAAAGACGTAGCATATCACTAATTAGATCA
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	TAGCTGATAGCCTGCAATATACAACCATCCGTTTT
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	ATCATATCTCTATAATTTCCTTTCATATCAACGC
GTCGCACCCTTTGCGGGTGCGTGGATTGAAAT	TAATAATGATTATTTTTTTATTAATTCATTAT
CATCGCCCCTTTGCGGGTGTGTAGTTTCAACT

Protein	Signature genes	Signature genes Name	Protein_function
CP021771.1\|AWZ33152.1\|313576_314221_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|224385
CP021771.1\|AWZ31546.1\|322273_322759_+\|phosphopantetheine-adenylyltransferase	unknown	unknown	gnl\|CDD\|173914
CP021771.1\|AWZ31535.1\|310799_312695_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|187773
CP021771.1\|AWZ31547.1\|322748_323822_+\|peptidase-S16	unknown	unknown	gnl\|CDD\|226011
CP021771.1\|AWZ31532.1\|306734_306926_-\|hypothetical-protein	unknown	unknown	unknown
CP021771.1\|AWZ31542.1\|319818_320811_+\|asparagine-synthetase-A	unknown	unknown	gnl\|CDD\|225304
CP021771.1\|AWZ31543.1\|320855_321305_-\|thiol-reductase-thioredoxin	unknown	unknown	gnl\|CDD\|273542
CP021771.1\|AWZ31531.1\|304863_305643_-\|hypothetical-protein	unknown	unknown	unknown
CP021771.1\|AWZ31545.1\|321986_322277_+\|hypothetical-protein	unknown	unknown	unknown
CP021771.1\|AWZ31539.1\|316458_317418_+\|gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
CP021771.1\|AWZ31548.1\|323896_325231_+\|phosphoesterase	unknown	unknown	gnl\|CDD\|277323
CP021771.1\|AWZ31538.1\|315253_315547_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
CP021771.1\|AWZ31534.1\|310071_310800_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
CP021771.1\|AWZ31537.1\|314217_315243_+\|subtype-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
CP021771.1\|AWZ31544.1\|321435_321975_+\|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	unknown	unknown	gnl\|CDD\|367574
CP021771.1\|AWZ31533.1\|307515_309939_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
CP021771.1\|AWZ31530.1\|301994_304646_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
CP021771.1\|AWZ31540.1\|317578_318481_+\|magnesium-transporter-CorA	unknown	unknown	gnl\|CDD\|213361
CP021771.1\|AWZ31536.1\|312699_313548_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
CP021771.1\|AWZ31541.1\|318641_319706_+\|MmcQ-family-protein	unknown	unknown	gnl\|CDD\|225197

Protein	Function_ID	Function_description	E-value
CP021771.1\|AWZ33152.1\|313576_314221_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	5.19253e-30
CP021771.1\|AWZ31546.1\|322273_322759_+\|phosphopantetheine-adenylyltransferase	gnl\|CDD\|173914	cd02163, PPAT, Phosphopantetheine adenylyltransferase. Phosphopantetheine adenylyltransferase (PPAT). PPAT is an essential enzyme in bacteria, responsible for catalyzing the rate-limiting step in coenzyme A (CoA) biosynthesis. The dinucleotide-binding fold of PPAT is homologous to class I aminoacyl-tRNA synthetases. CoA has been shown to inhibit PPAT and competes with ATP, PhP, and dPCoA. PPAT is a homohexamer in E. coli.	9.07742e-77
CP021771.1\|AWZ31535.1\|310799_312695_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187773	cd09642, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-C subtype; also known as Csd1 family.	0
CP021771.1\|AWZ31547.1\|322748_323822_+\|peptidase-S16	gnl\|CDD\|226011	COG3480, SdrC, Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms].	1.28781e-135
CP021771.1\|AWZ31542.1\|319818_320811_+\|asparagine-synthetase-A	gnl\|CDD\|225304	COG2502, AsnA, Asparagine synthetase A [Amino acid transport and metabolism].	0
CP021771.1\|AWZ31543.1\|320855_321305_-\|thiol-reductase-thioredoxin	gnl\|CDD\|273542	TIGR01295, Pediocin_PA-1_biosynthesis_protein_PedC, bacteriocin transport accessory protein, putative. This model describes a small family of proteins believed to aid in the export of various class II bacteriocins, which are ribosomally-synthesized, non-lantibiotic bacterial peptide antibiotics. Members of this family are found in operons for pediocin PA-1 from Pediococcus acidilactici and brochocin-C from Brochothrix campestris.	2.96539e-08
CP021771.1\|AWZ31539.1\|316458_317418_+\|gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.72879e-57
CP021771.1\|AWZ31548.1\|323896_325231_+\|phosphoesterase	gnl\|CDD\|277323	cd00845, MPP_UshA_N_like, Escherichia coli UshA-like family, N-terminal metallophosphatase domain. This family includes the bacterial enzyme UshA, and related enzymes including SoxB, CpdB, YhcR, and CD73. All members have a similar domain architecture which includes an N-terminal metallophosphatase domain and a C-terminal nucleotidase domain. The N-terminal metallophosphatase domain belongs to a large superfamily of distantly related metallophosphatases (MPPs) that includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	7.10499e-59
CP021771.1\|AWZ31538.1\|315253_315547_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.98207e-31
CP021771.1\|AWZ31537.1\|314217_315243_+\|subtype-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	5.95494e-174
CP021771.1\|AWZ31544.1\|321435_321975_+\|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	gnl\|CDD\|367574	pfam03602, Cons_hypoth95, Conserved hypothetical protein 95.	9.30355e-83
CP021771.1\|AWZ31533.1\|307515_309939_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.11439e-155
CP021771.1\|AWZ31534.1\|310071_310800_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	1.52076e-112
CP021771.1\|AWZ31541.1\|318641_319706_+\|MmcQ-family-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	1.01714e-19
CP021771.1\|AWZ31536.1\|312699_313548_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	5.09634e-156
CP021771.1\|AWZ31540.1\|317578_318481_+\|magnesium-transporter-CorA	gnl\|CDD\|213361	cd12827, EcCorA_ZntB-like_u2, uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family. A uncharacterized subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB (EcCorA-ZntB_like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes.The EcCorA-ZntB-like family includes the Mg2+ transporters Escherichia coli and Salmonella typhimurium CorAs, which can also transport Co2+, and Ni2+. Structures of the intracellular domain of EcCorA-ZntB-like family members, Vibrio parahaemolyticus and Salmonella typhimurium ZntB, form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA. Natural variants such as GVN and GIN, such as occur in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.	4.87179e-70
CP021771.1\|AWZ31530.1\|301994_304646_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0

>CP021771.1|AWZ31538.1|315253_315547_+|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVNTKTVAGRRRLRHVAKLCVDYGQRVQNSVFECSVTPAEFVEIKNELLTIIDQKSDSIRFYLLGKNWQNRVETIGKNDSYDPDIGVLLL
>CP021771.1|AWZ31537.1|314217_315243_+|subtype-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYLTQDNFYLTRERDNIVIKQEGKIVHRFPYRIIDGIICFSYLGASPSLIELCTEKQINLSFHTPQGRFCGRFVGSTNGNVLLRREHYRLADHALSIEYAKRFILAKVSNSRKYLIRFKRDHRDRIDIQLFEDINTELMWALELIQSAPDKETLLGIEGQAANQYFRAFNELVLTDKDTFRFNGRTRRPPQDCINALMSLGYSLLTYECQSALEAVGLDSYVGFYHTDRPGRASLALDLVEEFRSYIVDRFVFSLVNKGQLNKRHFDIKENSSVILTEKGRTIFIESWQKRKHTVVEHPFTKEKVKLMLLPYVQAQLLSKAIRGDLESYPPFLI
>CP021771.1|AWZ33152.1|313576_314221_+|CRISPR-associated-protein-Cas4
MLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQILHTKADNPYIKGKRKDFLVSRAMHVSSKILGLYGILDVVEFYKDENGFSLKGKRGKWLPCIVEYKRGKPKKDRRDIVQLVAQTICLEETFGCYIEKGCLYYHSVNQKKTIEITEELRQEVLDLAEQMHFYYDNKIIGKAEYFKNCPLCSLVDICKPRLSKKTRNVDNYIRQSLVNEDSL
>CP021771.1|AWZ31536.1|312699_313548_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MLEHKIDFIVTFEVKEANANGDPLNGNMPRTDAKGYGVMSDVSIKRKIRNRLQDMGKPIFVQANERIEDDFRSLEKRFSQHFTAKTPDKEIEEKANALWFDVRAFGQVFTYLKKSIGVRGPISISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTMGTKHFVDYGIYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRVREVFWFTHSSKLGNVSSARVFDLLEYNQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTVKILEGL
>CP021771.1|AWZ31535.1|310799_312695_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MDFFTSLLKTYEKAELADLVDHQKRNNEPVLLPIYHTSLKSNGKNIISVKLDKDGQFHKAEFMTDKQMIIFPVTADSVARSGSNPAPHPLVDKFAYYSAEMGQSQYDSFHKQLNNWIDYCEEGDVKRFLTIVQQFILKPEFLTLILDSLIGPDYQNNQLKVTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKTLHQSYISFVEANRENLGICNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLMIKYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDEDMPSVIALATEENKRIGKSFIKGQKLFANDATYYIAILNKTSNGRIALKYFRQIQASQLLTNLDKWQEKYSWESRSKSGKSRLRTPAFHDILNVSYGVDRDRFLELDNDNFKSDQVQKLVTSLIDGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLNHTNQNRSYLFGRLLAIFELIETLRYSLEGNGSDRITNAERYWTAYTGQPTKLMMLLENKIKPYEETLKLNRRGSWKKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYPKQNTEVTESEE
>CP021771.1|AWZ31534.1|310071_310800_+|type-I-C-CRISPR-associated-protein-Cas5
MYRSRDFYVRVSGQRALFTNPATKGGSERASYSVPTRQALNGIVDAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFIWNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRESVGLVDDISQEEYEAAVSYYNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMENGVITFKTQSDCDIVNTLSSYAFKVPGEIKSVNDEYMEYDAMEKGEN
>CP021771.1|AWZ31533.1|307515_309939_+|CRISPR-associated-helicase/endonuclease-Cas3
MMTKETLAHYQKKIEQESEKKQSLDEHLWHVACFSRQEASIIGQGDVLFLISLYHDLGKADRAFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKSRGVDKDERMTFNEMVGYVISAHHGMYDFCYCSDDAEYYSFNKFKNRINRDLDDYHYHEDIKGYAIKLEEKLCDYGYKDLRELIDKAFDNYQQAMSSLNWQDNSEWDYYQSCMVRLYLSLLKNADILDTVNAYGLEISPMDKTERSSLKHSYLAAIEQKYASFGRPNNQLNTIRTEIAERVKERGKRDSKGIYRLDLPTGAGKTNLSMRYAFHQLVHQDKSRFFYITPFLSVLEQNASEIRKVTGDLGVLEHHSNMVKQANEDDDKDSLLSAYLIDSWDSQVVLTSMVQFFQTLFKTKSANLRRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEIDHRICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVYLTDVINLILGEENSVLAIFNTKKTVHNCYTMLKDMTDRPIYQLSTNMCAQHRLDLVAKIKTELQNNTPIICISTQLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLTEIKAKKEATESILYKIGSPINISTLNRDFFEYYYANNQGLMDYPLEDNISIYDYLSLNTYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVPYGDAEKKLAYLEELGTSHFLSAEDYQTIKSLLKELQPFTVNVRENDPLLEATKSYLNGQILVLTSEYYDTERGVKYDSASFYF
>CP021771.1|AWZ31532.1|306734_306926_-|hypothetical-protein
MTKVKYSLFFLIYLALLYLTSIYFPAIYKVLMYLHFLCLFIFSIMFLYNLIVILKYIFTHKKK
>CP021771.1|AWZ31531.1|304863_305643_-|hypothetical-protein
MLNSDFIISKSLANYIHHRRLEVGVSSTDLAEISNMSKSDWESFEKNGGAIPLKSKDIILDLLFLERFPKEKECDFIDKLFEEAKENKLWPEKIYQTMGLTPALSFIAGCEILSDDINNDLEELSKLPKESHLGQLDTSLLLSLLPQQFITKYDYEFVYKLSKVLAQYTSRNKVGSSYTAHNVIEEICLYLIAKESILYFESLDENSHLQLKELLDYNDEWPFDIFDDMDSYTFLYTDIYIEEDSPYHFKNWFVPQFYL
>CP021771.1|AWZ31530.1|301994_304646_+|valine--tRNA-ligase
MSKELSPKYNPAEVEAGRYQTWLDQDVFKPSGDAEAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGISRYDLGREKFLDKVWEWKDEYAATIKSQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYNRGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVATTRPETMFGDVAVAVNPEDPRYKDLIGQNVILPIINKPIPIVADEHADPEFGTGVVKITPAHDPNDFAVGQRHNLPQVNVMNDDGTMNELADEFNGMDRFEARKAVVAKLESLGNLVKIEKMTHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDTFMSWMENVHDWVISRQLWWGHQIPAWYNVNGEMYVGEDAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTEAADFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFSNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLDQARENVEKVVNSQVGNVTDRWILHNLNETVGKITENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDEKVVTRSVLLYTLDQILRLLHPIMPFVTEEIFGQYAEGSIVLASYPQVNATFENQTAHKGVESLKDLIRSVRNSRAEVNVAPSKPITILVKTSDSELESFFKDNSNYIKRFTNPETLEISSAIATPELAMSSVITGAEIFLPLADLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQKEKDKQADYQAKYDATQERIVEMQKLVK
>CP021771.1|AWZ31539.1|316458_317418_+|gfo/Idh/MocA-family-oxidoreductase
MSKVRYGVVSTAKVAPRFIEGVRLAGNGEVVAVSSRTLESAQAFANKYHLPKAYDKLEDMLADESIDVIYVATINQDHYKVAKAALLAGKHVLVEKPFTLTYDQANELFALAESCNLFLMEAQKSVFIPMTQVIKKLLASGEIGEVISISSTTAYPNIDHVTWFRELELGGGTVHFMAPYALSYLQYLFDATITHASGTATFPKGQSDSQSKLLLQLSNGVLVDIFLTTRLNLPHEMIIYGTEGRLIIPHFWKTTHAKLVRNDTSAQTIQVDMVSDFEKEAYHVSQMILEGQRVSHIMTPQLTLSGVKIIEDLYRSWGK
>CP021771.1|AWZ31540.1|317578_318481_+|magnesium-transporter-CorA
MFSSDFGFEIINVDDLSLQEERFLPSELLAYARDENESSFVRDIEGHLTLVYQLLDTQGHVDDVRHVPRVIPVTLFLKEDGLFVLANHKNINLVKKALNRVEKVDSPKHLLLSLVTAFSKQYFDVLDTISEERDKLINDLRKRPNKSNLARLANLQSGTVHLMMGTKQNFEMLTDLQNIEQDKENTRNEKMQLQDAIIEARQLSNMCSLNSQVFQELSSSYNNVLSNNLNDNVTTLTIISIGISIIAMVTSFYGMNVKLPFDSVDAVWVLIILITTIITIMLSIVMYIYVHKEDNHPKHK
>CP021771.1|AWZ31541.1|318641_319706_+|MmcQ-family-protein
MSIESDFFRKKRFIFSSLEEFGFIKSDQEYIYCQTFMDNDFKAIITISLDGKIAGKVIDSALEEEYLPLRAANYNGSFVGEVRSAYMAILGDISDSCCKDLLFTKDQSNRLAEKIAKTFEDSVDYPFAKHPQYASYRVSGKWYALLFPLKMGKLENVPAQLSEDEVEVLNIKVNPQDMEILLQKEGIYPSYHMSKKTWVSIVLDNTLSDIEIFKLVSDSRKLVSPNKKSNSEPEFWIIPANPKFYDIDKEFAEHQLIDWTQKGKIAVGDYVFIYITAPIRALRYVCQVIERDLKTSTYLGARDVKAYMRLKLIRQFEDSTYPVAFLAEHGVKTVRGPRRMTKELRQVMAKTILE
>CP021771.1|AWZ31542.1|319818_320811_+|asparagine-synthetase-A
MKKSFIHQQQEISFVKNTFTQYLIDKLEIVEVQGPILSQVGDGMQDNLSGIEHPVSVKVLNIPEAEFEVVHSLAKWKRHTLARFGFNEGEGLFVHMKALRPDEDSLDPTHSVYVDQWDWEKVIPDGRRNLDYLKETVEKIYKAIRLTELAVEARFDIESILPKRITFIHTEELVEKYPDLSPKERENAIAKEYGAVFLIGIGGELADGKPHDGRAPDYDDWTTPSENGFKGLNGDILVWNEQLGTAFELSSMGIRVDEDALKRQVVLTGDEDRLEFEWHKTLLRGFFPLTIGGGIGQSRLAMFLLRKKHIGEVQSSVWPKEVRDTFENIL
>CP021771.1|AWZ31543.1|320855_321305_-|thiol-reductase-thioredoxin
MIKKLLLSLIAILCLTTLKSNLSSADTMTISPQQYQHMITNSDLIAITDKALVSKSQQSEATIFIGRPTCQYCRAFLPKLLKSQATLHSKIYYLDSQKYKGERLKSFFKKHHITTVPNLAHYQRGKMTKYLVQGSQATPQQIQTFLSQK
>CP021771.1|AWZ31544.1|321435_321975_+|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD
MRVVAGTFGGRPLKTLDGKTTRPTTDKVKGAIFNMIGPFFEGGRVLDLFSGSGSLAIEAISRGMDQAVLVEKDRRAQVVIQENIAMTKSPEQFQLLKMEANRALEQLTGQFDLVLLDPPYAKEEIVKQIQIMDSKGLLGDDIMIVCETDKSVDLPEEIASFGIWKQKIYGISKVTVYVR
>CP021771.1|AWZ31545.1|321986_322277_+|hypothetical-protein
MDYKLVMIILILVILIYLLLRLHYLEELLKHYHFKNDEGVCSLSRTKNPLYLLMAMITFLPNLINWIANGFEAIDIVRLIPVVVFLWLYYCGDDDE
>CP021771.1|AWZ31546.1|322273_322759_+|phosphopantetheine-adenylyltransferase
MTKKALFTGSFDPVTNGHLDIIERASYLFDHVYIGLFYNLEKQGYFSIECRKKMLEEAIRQFKNVSVLVAQDRLAVDLAREVGAKYFVRGLRNSQDFDYEANLEFFNKQLADDIETVYLSTSPSLSPISSSRIRELIHFKASVKPFVPKSVVREVEKMSEE
>CP021771.1|AWZ31547.1|322748_323822_+|peptidase-S16
MKNKDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATPAQVFYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESVYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHLADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVSSDVPVDFNTEGVGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKVQTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK
>CP021771.1|AWZ31548.1|323896_325231_+|phosphoesterase
MTELIRILHLNDLHSHFENFPKVKRFFHDNQAQPIETISLDLGDNIDKSHPLTEASSGKANIQLMNELGIELATIGNNEGVGLSKKDLDQVYKDSDFTVIVGNLKDNTIEPSWAKPYIIYETQQGTKLAFLAYTFPYYKTYEPHGWMIEDPIDCLKCHLQINEIKEANCRILMSHLGIRFDTRIAQEFSEIDLIIGAHTHHLFEEGELINGTYLAAAGKYGRFVGSIDITFDNHTLKDILISTCDTKQLTGYPSDSDWAKKIESEGKEQLRKESLISFPAPLSLEESCQLVMDAMLFYAGADVAIINSGLIVQPFRKDFSRKNLHESLPHQMRLAKLTVSSQELLEIYETIYQQGQFLAQQKIHGMGFRGKYFGDVLHSGFDYKNGKIVYNEKDIDAKEEVILVIVDQYYFASYFECLKTKKVDLLFPELLRDVVADYLINMTL

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Crispr_ID: CP021771_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021771_2

722837-723202

TypeII

II-A

Consensus_repeat	Method
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	PILER-CR
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CRISPRCasFinder
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CRT

5 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of CP021771_2

>merge|CP021771|2|722837-723202|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACCCACACGAGTGTGTGACTGTATGCGGTAAGGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACACCATCAAGACGCTTATTTGCAGATTGTTAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACCGGAACAATCAATCGAATTGAACGTATTGTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACATTTTTCTTTAGGCTACGACGGATAAGCTTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACATCTTCTTTTGACCTAACAAAAGGATATGTGTTTTAGAGCTGTGCTGTTATTATGCTAGGACATCA

>CP021771|2|2|722837-723136|PILER-CR
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CCACACGAGTGTGTGACTGTATGCGGTAAG
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ACCATCAAGACGCTTATTTGCAGATTGTTA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CGGAACAATCAATCGAATTGAACGTATTGT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTTTTCTTTAGGCTACGACGGATAAGCTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

>CP021771|2|2|722837-723136|CRISPRCasFinder
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CCACACGAGTGTGTGACTGTATGCGGTAAG
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ACCATCAAGACGCTTATTTGCAGATTGTTA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CGGAACAATCAATCGAATTGAACGTATTGT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTTTTCTTTAGGCTACGACGGATAAGCTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

>CP021771|2|2|722837-723202|CRT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CCACACGAGTGTGTGACTGTATGCGGTAAG
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ACCATCAAGACGCTTATTTGCAGATTGTTA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CGGAACAATCAATCGAATTGAACGTATTGT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTTTTCTTTAGGCTACGACGGATAAGCTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATCTTCTTTTGACCTAACAAAAGGATATGT
GTTTTAGAGCTGTGCTGTTATTATGCTAGGACATCA

Protein	Signature genes	Signature genes Name	Protein_function
CP021771.1\|AWZ31894.1\|722070_722736_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	pfam09711_csn2_CAS-II-A	gnl\|CDD\|213408
CP021771.1\|AWZ31887.1\|713086_714217_+\|coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
CP021771.1\|AWZ31897.1\|724311_726144_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
CP021771.1\|AWZ31903.1\|734856_735495_-\|chloramphenicol-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
CP021771.1\|AWZ31892.1\|720876_721746_+\|subtype-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
CP021771.1\|AWZ31898.1\|726404_729023_+\|internalin	unknown	unknown	gnl\|CDD\|380193
CP021771.1\|AWZ31889.1\|714958_715729_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
CP021771.1\|AWZ31902.1\|733632_734736_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371412
CP021771.1\|AWZ31901.1\|730840_733633_+\|haloacid-dehalogenase	unknown	unknown	gnl\|CDD\|223550
CP021771.1\|AWZ31896.1\|723759_724176_+\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
CP021771.1\|AWZ31900.1\|730254_730689_+\|peptide-methionine-(R)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|234692
CP021771.1\|AWZ31891.1\|716762_720875_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|273840
CP021771.1\|AWZ33168.1\|729170_729782_+\|phosphohydrolase	unknown	unknown	gnl\|CDD\|224336
CP021771.1\|AWZ31893.1\|721742_722084_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
CP021771.1\|AWZ31888.1\|714220_714958_+\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|366738
CP021771.1\|AWZ31890.1\|715718_716375_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
CP021771.1\|AWZ31895.1\|723456_723627_+\|hypothetical-protein	unknown	unknown	unknown
CP021771.1\|AWZ31886.1\|712614_712995_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131381
CP021771.1\|AWZ31885.1\|712218_712590_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377982
CP021771.1\|AWZ31899.1\|729790_730255_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181

Protein	Function_ID	Function_description	E-value
CP021771.1\|AWZ31894.1\|722070_722736_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.61399e-122
CP021771.1\|AWZ31897.1\|724311_726144_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
CP021771.1\|AWZ31903.1\|734856_735495_-\|chloramphenicol-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	9.50556e-71
CP021771.1\|AWZ31892.1\|720876_721746_+\|subtype-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	2.54315e-139
CP021771.1\|AWZ31898.1\|726404_729023_+\|internalin	gnl\|CDD\|380193	NF033189, internalin_A, class 1 internalin InlA. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface or secreted proteins with an N-terminal signal peptide, leucine-rich repeats, and usually a C-terminal LPXTG processing and cell surface anchoring site. See PMID:17764999 for a general discussion of internalins. Members of this family are internalin A (InlA), a class 1 (LPXTG-type) internalin.	1.10721e-21
CP021771.1\|AWZ31889.1\|714958_715729_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.19143e-132
CP021771.1\|AWZ31902.1\|733632_734736_+\|hypothetical-protein	gnl\|CDD\|371412	pfam11187, DUF2974, Protein of unknown function (DUF2974). This bacterial family of proteins has no known function.	1.82724e-105
CP021771.1\|AWZ31901.1\|730840_733633_+\|haloacid-dehalogenase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
CP021771.1\|AWZ31896.1\|723759_724176_+\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	4.64422e-78
CP021771.1\|AWZ31900.1\|730254_730689_+\|peptide-methionine-(R)-S-oxide-reductase	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	6.40832e-86
CP021771.1\|AWZ31891.1\|716762_720875_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|273840	TIGR01865, conserved_hypothetical_protein, CRISPR subtype II/NMENI RNA-guided endonuclease Cas9/Csn1. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein found only in CRISPR-containing species, near other CRISPR-associated proteins (cas), as part of the NMENI subtype of CRISPR/Cas locus. The species range so far for this protein is animal pathogens and commensals only.	0
CP021771.1\|AWZ33168.1\|729170_729782_+\|phosphohydrolase	gnl\|CDD\|224336	COG1418, COG1418, Predicted HD superfamily hydrolase [General function prediction only].	2.09273e-33
CP021771.1\|AWZ31893.1\|721742_722084_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.38084e-52
CP021771.1\|AWZ31888.1\|714220_714958_+\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|366738	pfam01643, Acyl-ACP_TE, Acyl-ACP thioesterase. This family consists of various acyl-acyl carrier protein (ACP) thioesterases (TE) these terminate fatty acyl group extension via hydrolysing an acyl group on a fatty acid.	3.68196e-111
CP021771.1\|AWZ31890.1\|715718_716375_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	9.75792e-52
CP021771.1\|AWZ31887.1\|713086_714217_+\|coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
CP021771.1\|AWZ31886.1\|712614_712995_+\|hypothetical-protein	gnl\|CDD\|131381	TIGR02328, TIGR02328, conserved hypothetical protein. Members of this protein are found in a small number of taxonomically well separated species, yet are strongly conserved, suggesting lateral gene transfer. Members are found in Treponema denticola, Clostridium acetobutylicum, and several of the Firmicutes. The function of this protein is unknown. [Hypothetical proteins, Conserved].	6.45558e-80
CP021771.1\|AWZ31885.1\|712218_712590_+\|hypothetical-protein	gnl\|CDD\|377982	pfam08349, DUF1722, Protein of unknown function (DUF1722). This domain of unknown function is found in bacteria and archaea and is homologous to the hypothetical protein ybgA from E. coli.	6.08694e-28
CP021771.1\|AWZ31899.1\|729790_730255_+\|N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.91796e-19

>CP021771.1|AWZ31894.1|722070_722736_+|type-II-A-CRISPR-associated-protein-Csn2
MIKINFPILDEPLVLSNATILTIEDVSVYSSLVKHFYQYDVDEHLKLFDDKQKSLKATELMLVTDILGYDVNSAPILKLIHGDLENQFNEKPEVKSMVEKLAATITELIAFECLENELDLEYDEITILELIKALGVKIETQSDTIFEKCFEIIQVYHYLTKKNLLVFVNSGAYLTKDEVIKLCEYINLMQKSVLFLEPRRLYDLPQYVIDKDYFLIGENMV
>CP021771.1|AWZ31893.1|721742_722084_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETAEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNTANNAMIGRLKVNNPKKGNITLLTVTEKQFARMVYLHGERNTSVANSDSRLVFLGDSYDQD
>CP021771.1|AWZ31892.1|720876_721746_+|subtype-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLIFKDSYQTEMIHLSEIDILIMETTDIVLSTMLIKRLVDENILVIFCDDKRLPTAMLMPYYARHDSSLQLSRQMSWIEDVKADVWTSIIAQKILNQSFYLGECSFFEKSQSIMNLYHDLEPFDPSNREGHAARIYFNTLFGNDFSREQDNPINAGLDYGYSLLLSMFAREVVKCGCMTQFGLKHANQFNQFNLASDIMEPFRPIVDRIIYENRQSDFVKMKRELFSMFSETYSYNGKEMYLSNIVSDYTKKVIKSLNSDGNGIPEFRI
>CP021771.1|AWZ31891.1|716762_720875_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MNKPYSIGLDIGTNSVGWSIITDDYKVPAKKMRVLGNTDKEYIKKNLIGALLFDGGNTAADRRLKRTARRRYTRRRNRILYLQEIFAEEMSKVDDSFFHRLEDSFLVEEDKRGSKYPIFATLQEEKDYHEKFSTIYHLRKELADKKEKADLRLIYIALAHIIKFRGHFLIEDDSFDVRNTDISKQYQDFLEIFNTTFENNDLLSQNVDVEAILTDKISKSAKKDRILAQYPNQKSTGIFAEFLKLIVGNQADFKKYFNLEDKTPLQFAKDSYDEDLENLLGQIGDEFADLFSAAKKLYDSVLLSGILTVIDLSTKAPLSASMIQRYDEHREDLKQLKQFVKASLPEKYQEIFADSSKDGYAGYIEGKTNQEAFYKYLSKLLTKQEDSENFLEKIKNEDFLRKQRTFDNGSIPHQVHLTELKAIIRRQSEYYPFLKENQDRIEKILTFRIPYYIGPLAREKSDFAWMTRKTDDSIRPWNFEDLVDKEKSAEAFIHRMTNNDFYLPEEKVLPKHSLIYEKFTVYNELTKVRYKNEQGETYFFDSNIKQEIFDGVFKEHRKVSKKKLLDFLAKEYEEFRIVDVIGLDKENKAFNASLGTYHDLEKILDKDFLDNPDNESILEDIVQTLTLFEDREMIKKRLENYKDLFTESQLKKLYRRHYTGWGRLSAKLINGIRDKESQKTILDYLIDDGRSNRNFMQLINDDGLSFKSIISKAQAGSHSDNLKEVVGELAGSPAIKKGILQSLKIVDELVKVMGYEPEQIVVEMARENQTTNQGRRNSRQRYKLLDDGVKNLASDLNGNILKEYPTDNQALQNERLFLYYLQNGRDMYTGEALDIDNLSQYDIDHIIPQAFIKDDSIDNRVLVSSAKNRGKSDDVPSLEIVKDCKVFWKKLLDAKLMSQRKYDNLTKAERGGLTSDDKARFIQRQLVETRQITKHVARILDERFNNELDSKGRRIRKVKIVTLKSNLVSNFRKEFGFYKIREVNNYHHAHDAYLNAVVAKAILTKYPQLEPEFVYGDYPKYNSYKTRKSATEKLFFYSNIMNFFKTKVTLADGTVVVKDDIEVNNDTGEIVWDKKKHFATVRKVLSYPQNNIVKKTEIQTGGFSKESILAHGNSDKLIPRKTKDIYLDPKKYGGFDSPIVAYSVLVVADIKKGKAQKLKTVTELLGITIMERSRFEKNPSAFLESKGYFNIRADKLIILPKYSLFELENGRRRLLASAGELQKGNELALPTQFMKFLYLASRYNESKGKPEEIEKKQEFVNQHVSYFDDILQLINDFSKRVILADANLEKINKLYQDNKENISVDELANNIINLFTFTSLGAPAAFKFFDKIVDRKRYTSTKEVLNSTLIHQSITGLYETRIDLGKLGED
>CP021771.1|AWZ31890.1|715718_716375_+|TIGR01906-family-membrane-protein
MKDKLLVVLTWIWIISLATLATIYIAWLIYPIEIQFLKLEKVVYLKAETIYYNFNKLMIYLTHPFISDLNMPSFPSSEDGLKHFADVKYLFTLAHGLFVILTFPVIYFLRRGWKQKSIFLYEGFFKIAIMLPIFIVVCAFLLGFDQFFTLFHEVLFPGDSTWQFNPLTDPVIWILPETFFLHCFIIFLLIYETITIILLIIGRKHLKLRKYKNKMQAL
>CP021771.1|AWZ31889.1|714958_715729_+|TIGR01457-family-HAD-type-hydrolase
MAYKGYLIDLDGTIYKGKSRIPAGERFIERLQEKGIPYMLVTNNTTRTPESVQEMLRGFNVETPLETIYTATMATVDYMNDMNRGKTAYVIGEEGLKKAIADAGYVEDTKNPAYVVVGLDWNVTYDKLATATLAIQNGALFIGTNPDLNIPTERGLLPGAGSLNALLEAATRIKPVFIGKPNAIIMNKALEILNIPRNQAVMVGDNYLTDIMAGINNDIDTLLVTTGFTTVEEVPDLPIQPSYVLASLDEWTFNEG
>CP021771.1|AWZ31888.1|714220_714958_+|acyl-[acyl-carrier-protein]-thioesterase
MGLLYRETYEVPFYESDTNHYMKLPQLLALALQISAKQSLKLGIGDDIVFKRYGLVWVVTDYIIDIERLPKHAEKIVIETEAKAHNKLLCYRYFYIYGEDGQKIITISSAFVLMDFKTRKIHPVLDDITSIYQSQRIKKVIRGPKYHPIGDSKVKQYHVRYFDLDMNGHVNNSKYLEWMYDVLDLDFLSSHIPKKIDLKYIKEIQYGTDIKSHWYQDGLVTRHDIIGGDAIHAQARIEWQEKKED
>CP021771.1|AWZ31887.1|713086_714217_+|coproporphyrinogen-III-oxidase
MLKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLQALIREFRSYDITELRTLYIGGGTPTSISAVQLDYLLTELSRDLNLNTLEEFTIEANPGDLTVDKIEVLQKSAVNRVSLGVQTFNDKHLKRIGRSHNEAQIYSTIDALKTAGFQNISIDLIYALPGQTMDDVRSNVAKALSLNIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEMFEYIISEMERNGFEHYEISNFTKPGFESRHNLMYWDNVEYYGVGAGASGYLDGIRYRNRGPIQHYLKGVSEGNARLSEEVLSKNEMMEEELFLGLRKKEGVSIGKFEQKFGTSFEKRYGQIVQELQSDGLLKENNGFIQMTKKGLFLGDTVAEKFIVE
>CP021771.1|AWZ31886.1|712614_712995_+|hypothetical-protein
MRLWHQDIIELLPRQQLLGQHRECCALRGNGWGRKHETVDYVFRYSPYRLFAYHQLVMEEMMERGYRVSKEWLIAEYRGMKCPRYDTLNPVDLETPIYPEHNQDYLQECLWNLKAKGIDLPINKIK
>CP021771.1|AWZ31885.1|712218_712590_+|hypothetical-protein
MTKEAELLWAKHKYLVLSKSQKIYLDIRQTLKSPNCTVLDVQSLIDQAVLLEESPSQVTNAYMHIWGYFKNKAERQEKEEFLTLLEKYRKTGYQRRKLLAFLKQLLAKYPNSYLQNSSIFEEE
>CP021771.1|AWZ31895.1|723456_723627_+|hypothetical-protein
MKGYNSNLMVKGLGCSTLYLIISLTALVLLVIAGVFFVINTCKLTRKAVENLSIIN
>CP021771.1|AWZ31896.1|723759_724176_+|nucleoside-diphosphate-kinase
MEQTFFMIKPDGVKRGFIGEVISRIERRGFSIDRLEVRYADADILKRHYAELTDRPFFPTLVDYMTSGPVIIGVISGEEVISTWRTMMGSTNPKDALPGTIRGDFAQAPSPNQATCNIVHGSDSPESATREIAIWFNN
>CP021771.1|AWZ31897.1|724311_726144_+|elongation-factor-4
MNIEDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRAEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGEVDAPLQALIFDSVYDAYRGVILQVRIVNGMVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVADTRVGDTITLANNPAIEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSEFPDPTRVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDDKK
>CP021771.1|AWZ31898.1|726404_729023_+|internalin
MIALAGLVLSCHFALTACHTQEHKNSHHIKTKQVAKKKANKKKVSVKESHKKRKGVAGVDFPTDDGFLLTKDSKILSHTDSGIVVAHGNHSHFIFYSDLKGSKFSYLIPNANTKTNKNQAVRNFKAGAVAVNTLNDGYVFNPADIVSEDANGYVVRHGDHFHYIPKASLSQQKQVQASRAVSRLGNQSNSHYRVNSSKIAGLHYPTSNGFLFNGRGIKGTTPTGILVEHHNHLHFISFADLRKGGWGSIADRYQPQKKADSKKQSPSSKKPRTENTLPKDIKDKLAYLARELHLDISRIRVLKTLNGEIGFEYPHDDHTHVIMAKDIDLSKPIPNPHHDDEDHHKGHHHDESDHKHEEHEHTKSNKLSDEDQKKLIYLAEKLGLNPNQIEVLTSEDGSIIFKYPHDDHSHTIASKDIEIGKPIPDGHHDHSHAKDKVGMATLKQIGFDDEIIQDILHADAPTPFPSNETNPEKMRQWLATVTKINIGQRTNPFQRFGLSLMPNIEVLGIGFTPINDMTPVLQFKKLKQLWMTNTGITDYSFLDKMPLLEGLDISQNGIKDLSFLTKYKQLSLIAAANNGITSLKPLAELPNLQFLVLSHNNISDLTPLSNLTKLQELHLDHNNVKNLSALSGKKDLKVLDLSNNKSADLSTLKTTSLETLLLNETNTSNLSFLKQNPKVSNLTINNAKLASLDGIEESDEIVKVEAEGNQIKSLVLKNKQGSLKFLNVTNNQLTSLEGVNNYTSLETLSVSKNKLESLDIKTPNKTVTNLDFSHNNVPTSQLKLNEKNIPEAVAKNFPAVVEGSMVGNGSLAEKAAMASKEDKQVSDNTNHQKNTEKSAQANADSKKENPKTHDEHHDHEETDHAHVGHHHH
>CP021771.1|AWZ33168.1|729170_729782_+|phosphohydrolase
MVHHKLKNDPSGHDWFHIVRVRNLAVELAHKEGANTFICQMAALLHDIIDDKICQDSKQASYELTQWLYSQDLAIAEVEHILDILENISFKAGTGLTMKTLEGQIVQDADRLDAMGAIGIARTMAYSGSKGRLIHDPNLKPRENLTLEEYRNGQDTAIMHFYEKLLKLKDLMNTKQGKMLAQKRHDFLELYLAEFYAEWNGKR
>CP021771.1|AWZ31899.1|729790_730255_+|N-acetyltransferase
MIRRAKEKDLPDIAELLKQILMLHHEVRPDIFHTRGSKFSKEQLKEMLIDESKPIFVYESDEGKVVAHLFLQLQEKRDLPRKSFKTLYIDDLCIDEEVRGQQIGQKLMDFARQYAKKHGCYNITLNVWNDNQRAVSFYEKLGFKPQQTQMEEIL
>CP021771.1|AWZ31900.1|730254_730689_+|peptide-methionine-(R)-S-oxide-reductase
MKETQEELRQRIGHTAYQVTQNSATEHAFTGKYDDFFEEGIYVDIVSGEVLFSSLDKFQSGCGWPAFSKPIENRMVTNHQDHSHGMHRIEVRSRQADSHLGHVFNDGPVDAGGLRYCINSAALDFIPYDQMAKRGYGDYLSLFD
>CP021771.1|AWZ31901.1|730840_733633_+|haloacid-dehalogenase
MASTNNVSDTNTRFAKEELEEVFEELGTTQGGLSDEEVAVRQKKYGLNLLSEVKQESIILLFLKNFTSLMAILLWVGGFVAIVSNSLELGLAIWMVNVINGIFSFIQEYRASQATQALEKMLPSYSRVLRKGSEEKILSEQLVPGDIVLIEEGDRISADGRLIKTTDLQVNQSALTGESNPIYKDSNVENDQSKTLIECDNMVFAGTTVSSGSATMVVTAIGMQTQFGQIADLTQGMKSEKSPLQRELDRLTKQISIISITVGIIFFLAATFFVKEPVSKSFIFALGMIVAFIPEGLLPTVTLSLAMAVQRMAKEHALVKKLSSVETLGATSVICSDKTGTLTQNEMTVNHLWQNGKSYQVTGLGYAPEGQILFEGDNICFGNSDRGDLEKLIRFAHLCSNAQVLPPNDDRSTYTVLGDPTEACLNVLLEKSGINIQENRKFAPRLKELPFDSVRKRMTTIHSLGGDEKDKKISITKGAPKEILDLSDYVLSDGKVIPLNKEERNKIQLANDTFAKDGLRVLAVSYCDIEGFSKEQWTQENLEQHMVFIGLIAMSDPPREGVREAIDKCHAASIRIIMVTGDYGLTALSIAKNIGIIRNDDAKVISGLELSEMTDSQLKKELSGEVVFARVAPEQKYRVVTILQEMGEVVAVTGDGVNDAPALKKSDIGVAMGVTGTDVAKESADMILTDDHFASIVHAVEEGRAVYQNIKKFLTYIFNSNTPEAVPSAFFLFSKGFIPLPLTVMQILAVDLGTDMLPALGLGVEPPETDVMNRPPRRLTDRLLDKGLLIKSFLWYGTIESVLAMGGFFWAHYLRYGNFTFFVANGIPYREATTMTLGAIIFSQIGMVMNSRTSYQSIKALSIFGNKLINFGIIMEILAFLVLVYVPLFHNLFNTASLGLSHWLYLISCPFIMIGLDEVRKLFSSRKNKR
>CP021771.1|AWZ31902.1|733632_734736_+|hypothetical-protein
MSNIITYLKNNSNLTFDELALNDVDILCLNEFGYISFEKLINTTEMKSVLVCELYHEYLQTMAKSYSFMFTSQRHDLCQLMMTSKRFKNLTLSYYRAEISLEFEKQFAAMVFTIPNINYHQVVFRGTDANLIGWKEDFKLTYMREISAHRSAIKYLNTILPYFDKVVLSGHSKGGNLALYAAMFTKPDLKAKIDLIWLIDSPGLQKTLLPTTEYKTTKQKCIRLLPEESIVGMMLYSDIEPLIISSNARGILQHDVTTWEIQEPAILKTGTGLSLKSICFEKTFQQWMAELKSQERKLFFDLLFDSFLSSGVSSLDDFNLASRAKMMKAFHSFRELDDDKKRLFNKSLKLLVTIFWGAYHDNSRETK
>CP021771.1|AWZ31903.1|734856_735495_-|chloramphenicol-acetyltransferase
MASILKKHLEKRLELKNDPMRTDMSTGASYPKYGFSVGKYTYGYQQFFYEGVNLKEIGAFCSIAQNVTITGLNHPTDHITTNPFIYYKSRGFINEDRADLIDEKKNGKVIIGNDVWIGTNVTILPSVTIGNGAIIGAGSVITKDIPDYGVVAGTPAKIIKYRFSEEEITLLNASQWWNWSDEAIKEHISEFSDKKEFFNTLKSISENKNHKL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP021771_1	1.3\|315795\|35\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	315795-315829	35	MK448796	Streptococcus phage Javan53, complete genome	31059-31093	0	1.0
CP021771_1	1.6\|315994\|34\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	315994-316027	34	MK448932	Streptococcus phage Javan42, complete genome	35042-35075	0	1.0
CP021771_1	1.8\|316126\|35\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	316126-316160	35	MK448768	Streptococcus phage Javan47, complete genome	34297-34331	0	1.0
CP021771_1	1.7\|316060\|34\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	316060-316093	34	MK448851	Streptococcus phage Javan14, complete genome	34030-34063	1	0.971
CP021771_2	2.4\|723071\|30\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	723071-723100	30	MK448729	Streptococcus phage Javan31, complete genome	12268-12297	1	0.967
CP021771_2	2.4\|723071\|30\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	723071-723100	30	MK448691	Streptococcus phage Javan17, complete genome	12268-12297	1	0.967
CP021771_2	2.4\|723071\|30\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	723071-723100	30	MK448948	Streptococcus phage Javan46, complete genome	12268-12297	1	0.967
CP021771_2	2.4\|723071\|30\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	723071-723100	30	MK448768	Streptococcus phage Javan47, complete genome	13413-13442	1	0.967
CP021771_2	2.1\|722873\|30\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	722873-722902	30	MF417967	Uncultured Caudovirales phage clone 3S_16, partial genome	12868-12897	2	0.933
CP021771_1	1.6\|315994\|34\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	315994-316027	34	MK449012	Streptococcus phage Javan94, complete genome	33617-33650	3	0.912
CP021771_1	1.7\|316060\|34\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	316060-316093	34	MK448796	Streptococcus phage Javan53, complete genome	38885-38918	3	0.912
CP021771_1	1.7\|316060\|34\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	316060-316093	34	MK448742	Streptococcus phage Javan37, complete genome	30083-30116	3	0.912
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_MG205643	Paeniclostridium sordellii strain S0804018 plasmid pCS1-5, complete sequence	72996-73027	5	0.844
CP021771_1	1.5\|315928\|34\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	315928-315961	34	NC_022111	Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence	606095-606128	6	0.824
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	548430-548461	6	0.812
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP038623	Arsenophonus nasoniae strain FIN plasmid pArsFIN11, complete sequence	39364-39395	6	0.812
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NC_017421	Borreliella burgdorferi N40 plasmid N40_lp38, complete sequence	28345-28376	6	0.812
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NC_001856	Borreliella burgdorferi B31 plasmid lp38, complete sequence	28055-28086	6	0.812
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP019853	Borreliella burgdorferi plasmid lp38, complete sequence	28068-28099	6	0.812
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP019764	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp38, complete sequence	28061-28092	6	0.812
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	484591-484622	7	0.781
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	AP014284	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S23-C63, * SEQUENCING IN PROGRESS *	9262-9293	7	0.781
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP014152	Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence	46517-46548	7	0.781
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	131643-131674	7	0.781
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP013684	Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence	15273-15304	7	0.781
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP013710	Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence	232837-232868	7	0.781
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NC_010379	Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence	25057-25088	7	0.781
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	158727-158758	7	0.781
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP013700	Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence	158558-158589	7	0.781
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	1638-1669	7	0.781
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NC_020380	Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-16, complete sequence	13185-13216	7	0.781
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	MH517022	Acinetobacter phage SH-Ab 15599, complete genome	51037-51068	7	0.781
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	MK496784	Capybara microvirus Cap3_SP_414, complete genome	2372-2403	7	0.781
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	U72945	Virus-like particle CAK1 of Clostridium beijerinckii origin of replication region	829-860	7	0.781
CP021771_2	2.1\|722873\|30\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	722873-722902	30	KT008108	Yersinia phage phiYe-F10, complete genome	8055-8084	7	0.767
CP021771_2	2.3\|723005\|30\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	723005-723034	30	MN855609	Siphoviridae sp. isolate 454, complete genome	1177-1206	7	0.767
CP021771_2	2.3\|723005\|30\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	723005-723034	30	MN855955	Bacteriophage sp. isolate 57, complete genome	15688-15717	7	0.767
CP021771_2	2.3\|723005\|30\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	723005-723034	30	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	37223-37252	7	0.767
CP021771_1	1.5\|315928\|34\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	315928-315961	34	NZ_LR214939	Mycoplasma salivarium strain NCTC10113 plasmid 2	617393-617426	8	0.765
CP021771_1	1.5\|315928\|34\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	315928-315961	34	NZ_CP030933	Enterococcus gilvus strain CR1 plasmid pCR1A, complete sequence	378878-378911	8	0.765
CP021771_1	1.5\|315928\|34\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	315928-315961	34	NC_015901	Lactococcus lactis subsp. lactis bv. diacetylactis plasmid pVF22, complete sequence	18325-18358	8	0.765
CP021771_1	1.9\|316193\|34\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	316193-316226	34	NZ_MH569712	Serratia marcescens strain S120 plasmid pPM120-2, complete sequence	42532-42565	8	0.765
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP029456	Bacillus cereus strain FORC087 plasmid pFORC087.2, complete sequence	61423-61454	8	0.75
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP022660	Salmonella enterica subsp. enterica strain RM11060 plasmid pRM11060-2, complete sequence	70696-70727	8	0.75
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	CP016196	Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-2, complete sequence	62259-62290	8	0.75
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP045061	Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p2, complete sequence	70700-70731	8	0.75
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP045054	Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p2, complete sequence	70707-70738	8	0.75
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP045058	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p2, complete sequence	70706-70737	8	0.75
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	MH830339	Proteus phage Stubb, complete genome	26806-26837	8	0.75
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	MG030347	Proteus phage PM135, complete genome	76557-76588	8	0.75
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	MN935203	UNVERIFIED: Proteus phage VTCCBPA139, partial genome	26007-26038	8	0.75
CP021771_2	2.1\|722873\|30\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	722873-722902	30	JQ691611	Cronobacter phage CR9, complete genome	114757-114786	8	0.733
CP021771_1	1.5\|315928\|34\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	315928-315961	34	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	243737-243770	9	0.735
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NC_007103	Bacillus cereus E33L plasmid pE33L466, complete sequence	93170-93201	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP009967	Bacillus cereus E33L plasmid pBCO_1, complete sequence	228972-229003	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_MG205643	Paeniclostridium sordellii strain S0804018 plasmid pCS1-5, complete sequence	9883-9914	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_AP017932	Lactobacillus sakei strain LK-145 plasmid pLs145-a, complete sequence	5632-5663	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP025208	Lactobacillus sakei strain WiKim0074 plasmid pLSW74_2, complete sequence	12385-12416	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP021933	Lactobacillus plantarum strain TMW 1.1478 plasmid pL11478-1, complete sequence	57054-57085	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP017376	Lactobacillus plantarum strain TMW 1.708 plasmid pL1708-2, complete sequence	17183-17214	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP021472	Pediococcus pentosaceus strain SRCM100892 plasmid pPC892-2, complete sequence	18052-18083	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP052067	Lactobacillus paracasei strain 347-16 plasmid unnamed2, complete sequence	1046-1077	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP031209	Lactobacillus brevis strain UCCLB521 plasmid pUCCLB521_A, complete sequence	42073-42104	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP035015	Lactobacillus plantarum strain 12_3 plasmid pldC, complete sequence	24116-24147	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NC_003383	Listeria innocua Clip11262 plasmid pLI100, complete sequence	34563-34594	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP048005	Lactobacillus paracasei strain CACC 566 plasmid p2CACC566, complete sequence	41814-41845	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP046038	Lactobacillus sakei strain CBA3614 plasmid unnamed1, complete sequence	31384-31415	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP017410	Lactobacillus plantarum strain RI-113 plasmid pRI113_4, complete sequence	12201-12232	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NC_016608	Pediococcus claussenii ATCC BAA-344 plasmid pPECL-5, complete sequence	15266-15297	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP029967	Lactobacillus curvatus strain ZJUNIT8 plasmid pnunamed1, complete sequence	42716-42747	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP028336	Lactobacillus plantarum strain SRCM101167 plasmid unnamed2, complete sequence	38185-38216	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP028231	Lactobacillus plantarum strain SRCM101222 plasmid unnamed2, complete sequence	3683-3714	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP018183	Lactobacillus nagelii strain TMW 1.1827 plasmid pL11827-3, complete sequence	17219-17250	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	MH937473	Streptococcus phage CHPC929, complete genome	34811-34842	9	0.719
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NC_010353	Streptococcus phage 858, complete genome	33013-33044	9	0.719
CP021771_1	1.9\|316193\|34\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	316193-316226	34	CP029330	Clostridium beijerinckii isolate WB53 plasmid unnamed1	3102-3135	10	0.706
CP021771_1	1.9\|316193\|34\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	316193-316226	34	CP029330	Clostridium beijerinckii isolate WB53 plasmid unnamed1	17601-17634	10	0.706
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP015507	Bacillus oceanisediminis 2691 plasmid pBO1, complete sequence	161310-161341	10	0.688
CP021771_1	1.5\|315928\|34\|CP021771\|PILER-CR,CRISPRCasFinder,CRT	315928-315961	34	NC_013792	Bacillus pseudofirmus OF4 plasmid pBpOF4-01, complete sequence	238853-238886	11	0.676
CP021771_1	1.10\|316259\|32\|CP021771\|CRT	316259-316290	32	NZ_CP031220	Arcobacter mytili LMG 24559 plasmid pAMYT, complete sequence	90370-90401	11	0.656

1. spacer 1.3|315795|35|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to MK448796 (Streptococcus phage Javan53, complete genome) position: , mismatch: 0, identity: 1.0

tactatatttccatttatgttctgtctgaaaagac	CRISPR spacer
tactatatttccatttatgttctgtctgaaaagac	Protospacer
***********************************

2. spacer 1.6|315994|34|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to MK448932 (Streptococcus phage Javan42, complete genome) position: , mismatch: 0, identity: 1.0

aggcaaaagtcaacgagctactcaaacagccaaa	CRISPR spacer
aggcaaaagtcaacgagctactcaaacagccaaa	Protospacer
**********************************

3. spacer 1.8|316126|35|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to MK448768 (Streptococcus phage Javan47, complete genome) position: , mismatch: 0, identity: 1.0

tagctgatagcctgcaatatacaaccatccgtttt	CRISPR spacer
tagctgatagcctgcaatatacaaccatccgtttt	Protospacer
***********************************

4. spacer 1.7|316060|34|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 1, identity: 0.971

gtcgtaaagacgtagcatatcactaattagatca	CRISPR spacer
gtcgtaaagacgtagcatatcactaattaaatca	Protospacer
*****************************.****

5. spacer 2.4|723071|30|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to MK448729 (Streptococcus phage Javan31, complete genome) position: , mismatch: 1, identity: 0.967

atttttctttaggctacgacggataagctt	CRISPR spacer
atttttctttaagctacgacggataagctt	Protospacer
***********.******************

6. spacer 2.4|723071|30|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to MK448691 (Streptococcus phage Javan17, complete genome) position: , mismatch: 1, identity: 0.967

atttttctttaggctacgacggataagctt	CRISPR spacer
atttttctttaagctacgacggataagctt	Protospacer
***********.******************

7. spacer 2.4|723071|30|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to MK448948 (Streptococcus phage Javan46, complete genome) position: , mismatch: 1, identity: 0.967

atttttctttaggctacgacggataagctt	CRISPR spacer
atttttctttaagctacgacggataagctt	Protospacer
***********.******************

8. spacer 2.4|723071|30|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to MK448768 (Streptococcus phage Javan47, complete genome) position: , mismatch: 1, identity: 0.967

atttttctttaggctacgacggataagctt	CRISPR spacer
atttttctttaagctacgacggataagctt	Protospacer
***********.******************

9. spacer 2.1|722873|30|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to MF417967 (Uncultured Caudovirales phage clone 3S_16, partial genome) position: , mismatch: 2, identity: 0.933

-ccacacgagtgtgtgactgtatgcggtaag	CRISPR spacer
gccacac-aatgtgtgactgtatgcggtaag	Protospacer
 ****** *.*********************

10. spacer 1.6|315994|34|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 3, identity: 0.912

aggcaaaagtcaacgagctactcaaacagccaaa	CRISPR spacer
aagcaaaagtcaacgagctactcaaacaaccaca	Protospacer
*.**************************.*** *

11. spacer 1.7|316060|34|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to MK448796 (Streptococcus phage Javan53, complete genome) position: , mismatch: 3, identity: 0.912

gtcgtaaagacgtagcatatcactaattagatca	CRISPR spacer
atcgtaaagacgtagcatatcactaattaagtca	Protospacer
.****************************..***

12. spacer 1.7|316060|34|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to MK448742 (Streptococcus phage Javan37, complete genome) position: , mismatch: 3, identity: 0.912

gtcgtaaagacgtagcatatcactaattagatca	CRISPR spacer
gtcgtaaagacgtagcatatcactaattaagtcg	Protospacer
*****************************..**.

13. spacer 1.10|316259|32|CP021771|CRT matches to NZ_MG205643 (Paeniclostridium sordellii strain S0804018 plasmid pCS1-5, complete sequence) position: , mismatch: 5, identity: 0.844

taataatg-attatttttttattaattcattat	CRISPR spacer
-aaaactgtattatttttatataaattcattat	Protospacer
 ** * ** ********* *** **********

14. spacer 1.5|315928|34|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to NC_022111 (Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence) position: , mismatch: 6, identity: 0.824

tattttatattaaaaataagactaccataattat-	CRISPR spacer
tattttatattgaaaataagaata-aataagaatg	Protospacer
***********.********* **  ****  **

15. spacer 1.10|316259|32|CP021771|CRT matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 6, identity: 0.812

taataatgattatttttttattaattcattat	CRISPR spacer
tattaatgattatttttttattagcaaatttt	Protospacer
** ********************..  *** *

16. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP038623 (Arsenophonus nasoniae strain FIN plasmid pArsFIN11, complete sequence) position: , mismatch: 6, identity: 0.812

taataatgattatttttttattaattcattat	CRISPR spacer
taataatgattatttagttattaacatataat	Protospacer
***************  *******. .** **

17. spacer 1.10|316259|32|CP021771|CRT matches to NC_017421 (Borreliella burgdorferi N40 plasmid N40_lp38, complete sequence) position: , mismatch: 6, identity: 0.812

taata-atgattatttttttattaattcattat	CRISPR spacer
-aatacctccttatttttttagttattcattat	Protospacer
 ****  *  *********** * *********

18. spacer 1.10|316259|32|CP021771|CRT matches to NC_001856 (Borreliella burgdorferi B31 plasmid lp38, complete sequence) position: , mismatch: 6, identity: 0.812

taata-atgattatttttttattaattcattat	CRISPR spacer
-aatacctccttatttttttagttattcattat	Protospacer
 ****  *  *********** * *********

19. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP019853 (Borreliella burgdorferi plasmid lp38, complete sequence) position: , mismatch: 6, identity: 0.812

taata-atgattatttttttattaattcattat	CRISPR spacer
-aatacctccttatttttttagttattcattat	Protospacer
 ****  *  *********** * *********

20. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP019764 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp38, complete sequence) position: , mismatch: 6, identity: 0.812

taata-atgattatttttttattaattcattat	CRISPR spacer
-aatacctccttatttttttagttattcattat	Protospacer
 ****  *  *********** * *********

21. spacer 1.10|316259|32|CP021771|CRT matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 7, identity: 0.781

taataatgattatttttttattaattcattat-	CRISPR spacer
agataatgatttgttttttattaatat-ttata	Protospacer
 .*********  ************ . ****

22. spacer 1.10|316259|32|CP021771|CRT matches to AP014284 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S23-C63, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.781

taataatgattatttttttattaattcattat	CRISPR spacer
ttctaataattttttttttattaattctggat	Protospacer
*  ****.*** ***************   **

23. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP014152 (Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence) position: , mismatch: 7, identity: 0.781

taata-atgattatttttttattaattcattat	CRISPR spacer
-agtataaaattccttttttattaattcattag	Protospacer
 *.** * .*** .******************

24. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 7, identity: 0.781

taata-atgattatttttttattaattcattat	CRISPR spacer
-agtataaaattccttttttattaattcattag	Protospacer
 *.** * .*** .******************

25. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP013684 (Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence) position: , mismatch: 7, identity: 0.781

taata-atgattatttttttattaattcattat	CRISPR spacer
-agtataaaatttcttttttattaattcattag	Protospacer
 *.** * .*** .******************

26. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP013710 (Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence) position: , mismatch: 7, identity: 0.781

taata-atgattatttttttattaattcattat	CRISPR spacer
-agtataaaattccttttttattaattcattag	Protospacer
 *.** * .*** .******************

27. spacer 1.10|316259|32|CP021771|CRT matches to NC_010379 (Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence) position: , mismatch: 7, identity: 0.781

taata-atgattatttttttattaattcattat	CRISPR spacer
-agtataaaattccttttttattaattcattag	Protospacer
 *.** * .*** .******************

28. spacer 1.10|316259|32|CP021771|CRT matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 7, identity: 0.781

taata-atgattatttttttattaattcattat	CRISPR spacer
-agtataaaattccttttttattaattcattag	Protospacer
 *.** * .*** .******************

29. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP013700 (Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence) position: , mismatch: 7, identity: 0.781

taata-atgattatttttttattaattcattat	CRISPR spacer
-agtataaaatttcttttttattaattcattag	Protospacer
 *.** * .*** .******************

30. spacer 1.10|316259|32|CP021771|CRT matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 7, identity: 0.781

taata-atgattatttttttattaattcattat	CRISPR spacer
-agtataaaattccttttttattaattcattag	Protospacer
 *.** * .*** .******************

31. spacer 1.10|316259|32|CP021771|CRT matches to NC_020380 (Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-16, complete sequence) position: , mismatch: 7, identity: 0.781

--taataatgattatttttttattaattcattat	CRISPR spacer
cgtagtgtt--ttatttttttattaattatttat	Protospacer
  **.*. *  *****************  ****

32. spacer 1.10|316259|32|CP021771|CRT matches to MH517022 (Acinetobacter phage SH-Ab 15599, complete genome) position: , mismatch: 7, identity: 0.781

taataatgattatttttttat--taattcattat	CRISPR spacer
taatagtgattatttttctattataatacgtc--	Protospacer
*****.***********.***  **** *.*.

33. spacer 1.10|316259|32|CP021771|CRT matches to MK496784 (Capybara microvirus Cap3_SP_414, complete genome) position: , mismatch: 7, identity: 0.781

taataatgattatttttttattaattcattat-	CRISPR spacer
tcgtaataatgatttttttattaatt-acgata	Protospacer
* .****.** *************** *. **

34. spacer 1.10|316259|32|CP021771|CRT matches to U72945 (Virus-like particle CAK1 of Clostridium beijerinckii origin of replication region) position: , mismatch: 7, identity: 0.781

-taataatgattatttttttattaattcattat	CRISPR spacer
tccataa-aattatttttttattaattgtttaa	Protospacer
 . **** .******************  ***

35. spacer 2.1|722873|30|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to KT008108 (Yersinia phage phiYe-F10, complete genome) position: , mismatch: 7, identity: 0.767

ccacacgagtgtgtgactgtatgcggtaag	CRISPR spacer
gcgcctgagtgtgcgcctgtatgcggtaat	Protospacer
 *.* .*******.* *************

36. spacer 2.3|723005|30|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to MN855609 (Siphoviridae sp. isolate 454, complete genome) position: , mismatch: 7, identity: 0.767

cggaacaatcaatcgaattgaacgtattgt	CRISPR spacer
caatccaatcaatgggattgaacgtattga	Protospacer
*..  ******** *.*************

37. spacer 2.3|723005|30|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to MN855955 (Bacteriophage sp. isolate 57, complete genome) position: , mismatch: 7, identity: 0.767

cggaacaatcaatcgaattgaacgtattgt	CRISPR spacer
caatccaatcaatgggattgaacgtattga	Protospacer
*..  ******** *.*************

38. spacer 2.3|723005|30|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 7, identity: 0.767

cggaacaatcaatcgaattgaacgtattgt	CRISPR spacer
cgatacaatcaatagaattgaacatatcaa	Protospacer
**. ********* *********.***..

39. spacer 1.5|315928|34|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214939 (Mycoplasma salivarium strain NCTC10113 plasmid 2) position: , mismatch: 8, identity: 0.765

tattttatattaaaaataagactaccataattat	CRISPR spacer
gtgtttatattaaacataagactaacatttttgt	Protospacer
   *********** ********* ***  **.*

40. spacer 1.5|315928|34|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030933 (Enterococcus gilvus strain CR1 plasmid pCR1A, complete sequence) position: , mismatch: 8, identity: 0.765

tattttat-attaaaaataagactaccataattat	CRISPR spacer
-gtaaaatgattaaaaataagactactttaatttt	Protospacer
 .*   ** *****************. ***** *

41. spacer 1.5|315928|34|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to NC_015901 (Lactococcus lactis subsp. lactis bv. diacetylactis plasmid pVF22, complete sequence) position: , mismatch: 8, identity: 0.765

tattttatattaaaaataagactaccataattat	CRISPR spacer
tattttatattaaaaattagaataatagaaatta	Protospacer
***************** *** ** .* ** *

42. spacer 1.9|316193|34|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MH569712 (Serratia marcescens strain S120 plasmid pPM120-2, complete sequence) position: , mismatch: 8, identity: 0.765

atcat-atctctataatttcctttcatatcaacgc	CRISPR spacer
-ttatgagtgctataatttccttttagatcaacga	Protospacer
 *.** * . **************.* *******

43. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP029456 (Bacillus cereus strain FORC087 plasmid pFORC087.2, complete sequence) position: , mismatch: 8, identity: 0.75

taataat-gattatttttttattaattcattat	CRISPR spacer
-agcattggattatttttctattaattaatttc	Protospacer
 *..* * **********.******** *** .

44. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP022660 (Salmonella enterica subsp. enterica strain RM11060 plasmid pRM11060-2, complete sequence) position: , mismatch: 8, identity: 0.75

taataatgattatttttttattaattcattat	CRISPR spacer
ttgttaatattattttttcattaatttattaa	Protospacer
* .* *  **********.*******.****

45. spacer 1.10|316259|32|CP021771|CRT matches to CP016196 (Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-2, complete sequence) position: , mismatch: 8, identity: 0.75

taataatgattatttttttattaattcattat	CRISPR spacer
tatattttattatttttttattagtttattaa	Protospacer
**    * ***************.**.****

46. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP045061 (Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p2, complete sequence) position: , mismatch: 8, identity: 0.75

taataatgattatttttttattaattcattat	CRISPR spacer
ttgttaatattattttttcattaatttattaa	Protospacer
* .* *  **********.*******.****

47. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP045054 (Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p2, complete sequence) position: , mismatch: 8, identity: 0.75

taataatgattatttttttattaattcattat	CRISPR spacer
ttgttaatattattttttcattaatttattaa	Protospacer
* .* *  **********.*******.****

48. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP045058 (Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p2, complete sequence) position: , mismatch: 8, identity: 0.75

taataatgattatttttttattaattcattat	CRISPR spacer
ttgttaatattattttttcattaatttattaa	Protospacer
* .* *  **********.*******.****

49. spacer 1.10|316259|32|CP021771|CRT matches to MH830339 (Proteus phage Stubb, complete genome) position: , mismatch: 8, identity: 0.75

taataatgattatttttttattaat-----tcattat	CRISPR spacer
ttattatgattatttatttattaataatgctc-----	Protospacer
* ** ********** *********     **

50. spacer 1.10|316259|32|CP021771|CRT matches to MG030347 (Proteus phage PM135, complete genome) position: , mismatch: 8, identity: 0.75

taataatgattatttttttattaat-----tcattat	CRISPR spacer
ttattatgattatttatttattaataatgctc-----	Protospacer
* ** ********** *********     **

51. spacer 1.10|316259|32|CP021771|CRT matches to MN935203 (UNVERIFIED: Proteus phage VTCCBPA139, partial genome) position: , mismatch: 8, identity: 0.75

taataatgattatttttttattaat-----tcattat	CRISPR spacer
ttattatgattatttatttattaataatgctc-----	Protospacer
* ** ********** *********     **

52. spacer 2.1|722873|30|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to JQ691611 (Cronobacter phage CR9, complete genome) position: , mismatch: 8, identity: 0.733

ccacacgagtgtgtgactgtatgcggtaag	CRISPR spacer
gcacaggagtgtgtgaatgtatgcgtcgcc	Protospacer
 **** ********** ******** ..

53. spacer 1.5|315928|34|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 9, identity: 0.735

tattttata------ttaaaaataagactaccataattat	CRISPR spacer
------ataaacactttaaaaataatactacaataattaa	Protospacer
      ***      ********** ***** *******

54. spacer 1.10|316259|32|CP021771|CRT matches to NC_007103 (Bacillus cereus E33L plasmid pE33L466, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
ctcctaaatttatttttttataaattcattat	Protospacer
.  . * . ************ **********

55. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP009967 (Bacillus cereus E33L plasmid pBCO_1, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
ctcctaaatttatttttttataaattcattat	Protospacer
.  . * . ************ **********

56. spacer 1.10|316259|32|CP021771|CRT matches to NZ_MG205643 (Paeniclostridium sordellii strain S0804018 plasmid pCS1-5, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
agataatgattacttttatattaatagttttg	Protospacer
 .**********.**** *******   **

57. spacer 1.10|316259|32|CP021771|CRT matches to NZ_AP017932 (Lactobacillus sakei strain LK-145 plasmid pLs145-a, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

58. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP025208 (Lactobacillus sakei strain WiKim0074 plasmid pLSW74_2, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

59. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP021933 (Lactobacillus plantarum strain TMW 1.1478 plasmid pL11478-1, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

60. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP017376 (Lactobacillus plantarum strain TMW 1.708 plasmid pL1708-2, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

61. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP021472 (Pediococcus pentosaceus strain SRCM100892 plasmid pPC892-2, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

62. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP052067 (Lactobacillus paracasei strain 347-16 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

63. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP031209 (Lactobacillus brevis strain UCCLB521 plasmid pUCCLB521_A, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

64. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP035015 (Lactobacillus plantarum strain 12_3 plasmid pldC, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

65. spacer 1.10|316259|32|CP021771|CRT matches to NC_003383 (Listeria innocua Clip11262 plasmid pLI100, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttatta-attcattat	CRISPR spacer
taataatgataatttttttgttacacctgcca-	Protospacer
********** ********.*** *......*

66. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP048005 (Lactobacillus paracasei strain CACC 566 plasmid p2CACC566, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

67. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP046038 (Lactobacillus sakei strain CBA3614 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

68. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP017410 (Lactobacillus plantarum strain RI-113 plasmid pRI113_4, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

69. spacer 1.10|316259|32|CP021771|CRT matches to NC_016608 (Pediococcus claussenii ATCC BAA-344 plasmid pPECL-5, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

70. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP029967 (Lactobacillus curvatus strain ZJUNIT8 plasmid pnunamed1, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

71. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP028336 (Lactobacillus plantarum strain SRCM101167 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

72. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP028231 (Lactobacillus plantarum strain SRCM101222 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

73. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP018183 (Lactobacillus nagelii strain TMW 1.1827 plasmid pL11827-3, complete sequence) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
caataatcattgtttttttattaaattgggtt	Protospacer
.****** ***.************ *..   *

74. spacer 1.10|316259|32|CP021771|CRT matches to MH937473 (Streptococcus phage CHPC929, complete genome) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
tttacttacttacttttttattaattcaatat	Protospacer
*     *. ***.*************** ***

75. spacer 1.10|316259|32|CP021771|CRT matches to NC_010353 (Streptococcus phage 858, complete genome) position: , mismatch: 9, identity: 0.719

taataatgattatttttttattaattcattat	CRISPR spacer
tttacttacttacttttttattaattcaatat	Protospacer
*     *. ***.*************** ***

76. spacer 1.9|316193|34|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to CP029330 (Clostridium beijerinckii isolate WB53 plasmid unnamed1) position: , mismatch: 10, identity: 0.706

atcatatctctataatttcctttcatatcaacgc	CRISPR spacer
cttatatctttataattttctttcatatagtttg	Protospacer
 *.******.********.********* . .

77. spacer 1.9|316193|34|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to CP029330 (Clostridium beijerinckii isolate WB53 plasmid unnamed1) position: , mismatch: 10, identity: 0.706

atcatatctctataatttcctttcatatcaacgc	CRISPR spacer
cttatatctttataattttctttcatatagtttg	Protospacer
 *.******.********.********* . .

78. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP015507 (Bacillus oceanisediminis 2691 plasmid pBO1, complete sequence) position: , mismatch: 10, identity: 0.688

taataatgattatttttttattaattcattat	CRISPR spacer
aagggtagattattttttcatttattcatttc	Protospacer
 *. .  ***********.*** ******* .

79. spacer 1.5|315928|34|CP021771|PILER-CR,CRISPRCasFinder,CRT matches to NC_013792 (Bacillus pseudofirmus OF4 plasmid pBpOF4-01, complete sequence) position: , mismatch: 11, identity: 0.676

tattttatattaaaaataagactaccataattat	CRISPR spacer
tattttatattaaaaataaaattagtggtgaaaa	Protospacer
*******************.*.** ..  .  *

80. spacer 1.10|316259|32|CP021771|CRT matches to NZ_CP031220 (Arcobacter mytili LMG 24559 plasmid pAMYT, complete sequence) position: , mismatch: 11, identity: 0.656

taataatgattatttttttattaattcattat	CRISPR spacer
cccatttgaatatttatttattaattcatcta	Protospacer
.     *** ***** *************.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

982564 : 1067868

Streptococcus_phage(60.71%)

transposase,protease,tail,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ32133.1\|982564_983275_-\|protease	Zn-dependent protease	NA	NA	NA	NA
AWZ32134.1\|983364_984153_-	esterase family protein	NA	NA	NA	NA
AWZ32135.1\|984209_985871_-	ribonuclease J	NA	NA	NA	NA
AWZ32136.1\|986167_986929_-	phosphonate ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	4.1e-12	29.3
AWZ32137.1\|986928_987792_-	ABC transporter permease	NA	NA	NA	NA
AWZ32138.1\|987804_988809_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
AWZ32139.1\|989166_990822_+	fibronectin/fibrinogen-binding protein	A0A1J0F9J4	Only_Syngen_Nebraska_virus	2.3e-07	41.0
AWZ32140.1\|990875_991595_-	alpha-acetolactate decarboxylase	NA	NA	NA	NA
AWZ32141.1\|991608_993291_-	acetolactate synthase AlsS	NA	NA	NA	NA
AWZ32142.1\|993400_994627_-	hypothetical protein	NA	NA	NA	NA
AWZ32143.1\|994616_995807_-	AI-2E family transporter	NA	NA	NA	NA
AWZ32144.1\|995898_996360_-	DNA mismatch repair protein MutT	NA	NA	NA	NA
AWZ32145.1\|996349_996832_-	7,8-dihydro-8-oxoguanine triphosphatase	NA	NA	NA	NA
AWZ32146.1\|997048_1000267_+	hyaluronate lyase	NA	NA	NA	NA
AWZ32147.1\|1000318_1001365_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.9e-68	43.6
AWZ32148.1\|1001571_1002165_-	dTDP-4-dehydrorhamnose 3,5-epimerase	NA	NA	NA	NA
AWZ32149.1\|1002164_1003034_-	glucose-1-phosphate thymidylyltransferase	I7I009	Enterobacteria_phage	2.7e-100	62.2
AWZ32150.1\|1003092_1004196_-	FAD-binding oxidoreductase	NA	NA	NA	NA
AWZ32151.1\|1004204_1004993_-	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
AWZ32152.1\|1004982_1005666_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
AWZ32153.1\|1005769_1006450_-	DNA replication protein DnaD	Q938N2	Temperate_phage	1.9e-08	31.8
AWZ32154.1\|1006567_1007086_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	4.6e-31	44.1
AWZ32155.1\|1007208_1009773_-	hypothetical protein	NA	NA	NA	NA
AWZ32156.1\|1009756_1009855_-	hypothetical protein	NA	NA	NA	NA
AWZ32157.1\|1009924_1012123_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-72	28.9
AWZ32158.1\|1012119_1012881_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
AWZ32159.1\|1012882_1013812_-	ribonuclease Z	NA	NA	NA	NA
AWZ32160.1\|1013853_1014501_-	cystathionine beta-lyase	NA	NA	NA	NA
AWZ32161.1\|1014493_1015732_-	GTPase HflX	NA	NA	NA	NA
AWZ32162.1\|1015822_1016713_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
AWZ32163.1\|1016823_1017000_+	DUF3042 domain-containing protein	NA	NA	NA	NA
AWZ32164.1\|1017041_1017959_-	ethanolamine utilization protein EutK	NA	NA	NA	NA
AWZ32165.1\|1018093_1021852_-	pullulanase	NA	NA	NA	NA
AWZ32166.1\|1022020_1022755_-	hypothetical protein	NA	NA	NA	NA
AWZ32167.1\|1022769_1023354_-	uracil-DNA glycosylase	NA	NA	NA	NA
AWZ32168.1\|1023450_1024857_-	dipeptidase PepV	NA	NA	NA	NA
AWZ32169.1\|1024903_1025506_-	nitroreductase family protein	NA	NA	NA	NA
AWZ32170.1\|1025675_1027457_+	glycerophosphodiester phosphodiesterase	I6XE30	Staphylococcus_phage	2.7e-06	23.7
AWZ32171.1\|1027498_1029280_-	UvrABC system protein C	NA	NA	NA	NA
AWZ32172.1\|1029438_1030206_+	DNA integration/recombination/inversion protein	NA	NA	NA	NA
AWZ32173.1\|1030264_1031605_-	MATE family efflux transporter	NA	NA	NA	NA
AWZ32174.1\|1031704_1032115_-	VOC family protein	NA	NA	NA	NA
AWZ32175.1\|1032124_1032622_-\|tail	phage tail protein	NA	NA	NA	NA
AWZ32176.1\|1032843_1033440_+	hypothetical protein	NA	NA	NA	NA
AWZ32177.1\|1033628_1034733_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	3.7e-70	48.9
AWZ32178.1\|1036135_1036369_+\|transposase	transposase	NA	NA	NA	NA
AWZ32179.1\|1036567_1039036_-	histidine triad (HIT) protein	NA	NA	NA	NA
AWZ32180.1\|1039048_1039969_-	adhesion protein	NA	NA	NA	NA
AWZ32181.1\|1040046_1040163_-	exfoliative toxin	NA	NA	NA	NA
AWZ32182.1\|1040146_1041280_-\|transposase	ISAs1 family transposase IS1548	NA	NA	NA	NA
AWZ32183.1\|1041530_1044983_-	peptidase C5	A0A218KC60	Bacillus_phage	7.6e-05	39.4
AWZ32184.1\|1047997_1049812_-	DNA polymerase III subunit epsilon	A0A0A7RWA3	Clostridium_phage	5.0e-32	31.9
AWZ32185.1\|1050345_1051563_-\|transposase	transposase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
AWZ32186.1\|1051644_1051848_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
AWZ32187.1\|1051831_1052083_+	hypothetical protein	NA	NA	NA	NA
AWZ32188.1\|1052308_1052539_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
AWZ32189.1\|1052535_1052958_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
AWZ33175.1\|1053186_1053258_-	hypothetical protein	NA	NA	NA	NA
AWZ32190.1\|1053462_1053816_+	transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
AWZ32191.1\|1053875_1054061_-	conjugal transfer protein	D0R0F6	Streptococcus_phage	3.9e-17	67.9
AWZ32192.1\|1054161_1056081_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	99.5
AWZ32193.1\|1056096_1056183_-	tetracycline resistance protein	NA	NA	NA	NA
AWZ32194.1\|1057386_1058388_-	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
AWZ32195.1\|1058384_1060562_-	hypothetical protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
AWZ32196.1\|1060564_1063012_-	ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
AWZ32197.1\|1062995_1063502_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
AWZ32198.1\|1063476_1063974_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
AWZ32199.1\|1064090_1064312_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
AWZ32200.1\|1064354_1065560_-	replication initiation protein	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
AWZ32201.1\|1065582_1065735_-	conjugal transfer protein	NA	NA	NA	NA
AWZ32202.1\|1065737_1067123_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
AWZ32203.1\|1067151_1067538_-	conjugal transfer protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
AWZ32204.1\|1067553_1067868_-	conjugal transfer protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0

DBSCAN-SWA_2

1301514 : 1357931

Streptococcus_phage(47.62%)

protease,coat,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ32419.1\|1301514_1302681_+\|transposase	IS30 family transposase	NA	NA	NA	NA
AWZ32420.1\|1303014_1304397_-	MFS transporter	NA	NA	NA	NA
AWZ32421.1\|1305096_1306230_+\|transposase	ISAs1 family transposase IS1548	NA	NA	NA	NA
AWZ32422.1\|1306213_1306318_+	exfoliative toxin	NA	NA	NA	NA
AWZ33186.1\|1307223_1308108_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	7.1e-24	27.9
AWZ32423.1\|1308168_1308522_+	hypothetical protein	NA	NA	NA	NA
AWZ33187.1\|1308703_1309937_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.4e-64	50.0
AWZ32424.1\|1309986_1311702_-	aminodeoxychorismate synthase, component I	S4VT78	Pandoravirus	3.7e-37	30.8
AWZ32425.1\|1311783_1314234_-	cell division protein FtsK	S5VNE3	Mycobacterium_phage	3.9e-88	51.7
AWZ32426.1\|1314399_1315203_+	peptidyl-prolyl cis-trans isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	38.4
AWZ32427.1\|1315254_1316088_-	manganese ABC transporter permease	NA	NA	NA	NA
AWZ32428.1\|1316089_1316806_-	manganese ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	5.6e-19	32.5
AWZ32429.1\|1316976_1317903_-	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
AWZ32430.1\|1318069_1318717_+	MarR family transcriptional regulator	NA	NA	NA	NA
AWZ32431.1\|1318756_1319446_-	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	NA	NA	NA	NA
AWZ32432.1\|1319455_1319725_-	hypothetical protein	NA	NA	NA	NA
AWZ32433.1\|1319724_1320279_-	NUDIX hydrolase	NA	NA	NA	NA
AWZ32434.1\|1320299_1321679_-	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase	A0A2K9L4K9	Tupanvirus	2.6e-33	37.2
AWZ32435.1\|1321922_1322336_-	VOC family protein	NA	NA	NA	NA
AWZ32436.1\|1322348_1322726_-	glyoxalase/bleomycin resistance/extradiol dioxygenase family protein	NA	NA	NA	NA
AWZ32437.1\|1322814_1323771_-	gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
AWZ32438.1\|1324457_1325156_-	NAD(P)-dependent dehydrogenase	NA	NA	NA	NA
AWZ32439.1\|1325148_1325385_-	hypothetical protein	NA	NA	NA	NA
AWZ32440.1\|1325474_1325723_-	hypothetical protein	NA	NA	NA	NA
AWZ32441.1\|1325920_1326421_-	N-acetyltransferase	NA	NA	NA	NA
AWZ32442.1\|1326660_1328073_-	glycosyl transferase family 2	NA	NA	NA	NA
AWZ32443.1\|1328212_1330372_-	hypothetical protein	NA	NA	NA	NA
AWZ33188.1\|1330378_1331812_-\|coat	spore coat protein CotH	NA	NA	NA	NA
AWZ32444.1\|1331816_1332494_-	DUF4956 domain-containing protein	NA	NA	NA	NA
AWZ32445.1\|1332545_1333241_-	molecular chaperone	NA	NA	NA	NA
AWZ32446.1\|1333605_1334943_-	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
AWZ32447.1\|1335138_1337136_-\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	1.3e-97	39.6
AWZ32448.1\|1337278_1338154_+	tellurite resistance methyltransferase TehB	NA	NA	NA	NA
AWZ32449.1\|1338311_1339007_-	DUF1275 family protein	NA	NA	NA	NA
AWZ32450.1\|1339021_1339144_-	hypothetical protein	NA	NA	NA	NA
AWZ32451.1\|1339342_1340560_+	PTS lactose transporter subunit IIC	NA	NA	NA	NA
AWZ32452.1\|1340543_1341386_+	acyltransferase	NA	NA	NA	NA
AWZ32453.1\|1341462_1342290_+	exodeoxyribonuclease	M1PSC0	Streptococcus_phage	4.3e-124	78.0
AWZ32454.1\|1342329_1342686_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.5e-41	71.8
AWZ32455.1\|1342687_1343164_-	cysteine methyltransferase	M1PFU9	Streptococcus_phage	7.1e-39	50.9
AWZ32456.1\|1343218_1344400_-	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	7.0e-168	75.6
AWZ32457.1\|1344462_1344969_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	9.6e-50	58.6
AWZ32458.1\|1346302_1346938_+	copper homeostasis protein CutC	NA	NA	NA	NA
AWZ32459.1\|1346981_1347086_-	hypothetical protein	NA	NA	NA	NA
AWZ32460.1\|1347070_1347232_+	hypothetical protein	NA	NA	NA	NA
AWZ33189.1\|1347207_1348071_-	rRNA (cytidine-2'-O-)-methyltransferase	M1PLC5	Streptococcus_phage	3.7e-110	70.4
AWZ32461.1\|1348076_1348403_-	initiation-control protein YabA	M1PFV3	Streptococcus_phage	3.2e-30	61.1
AWZ32462.1\|1348432_1349296_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	7.3e-74	49.7
AWZ32463.1\|1349315_1349951_-	thymidylate kinase	M1PSC7	Streptococcus_phage	2.8e-67	61.1
AWZ32464.1\|1350159_1351326_+\|transposase	IS30 family transposase ISSag9	NA	NA	NA	NA
AWZ32465.1\|1351590_1352250_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	5.2e-64	55.6
AWZ32466.1\|1352268_1352979_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-18	28.5
AWZ32467.1\|1352978_1353743_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.4e-14	24.3
AWZ32468.1\|1353743_1354697_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
AWZ32469.1\|1354699_1355569_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
AWZ32470.1\|1355674_1356841_-	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
AWZ32471.1\|1356995_1357241_-	hypothetical protein	NA	NA	NA	NA
AWZ32472.1\|1357340_1357931_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	3.7e-53	54.6

DBSCAN-SWA_3

1827791 : 1839652

Streptococcus_phage(63.64%)

integrase

attL 1825826:1825845|attR 1839757:1839776

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1825826:1825845	attL	NA	NA	NA	NA
AWZ32929.1\|1827791_1828280_-	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	1.2e-46	56.2
AWZ32930.1\|1828364_1828970_-	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	7.0e-39	46.8
AWZ32931.1\|1829153_1829327_-	DUF2758 domain-containing protein	A0A1X9I5U0	Streptococcus_phage	1.9e-10	59.6
AWZ32932.1\|1829586_1831089_-	DNA primase	Q9AZI5	Lactococcus_phage	2.7e-63	37.2
AWZ32933.1\|1831108_1831966_-	hypothetical protein	A0A1X9I6L2	Streptococcus_phage	4.3e-119	72.0
AWZ32934.1\|1831966_1832239_-	transcriptional regulator	A0A1X9I5U9	Streptococcus_phage	2.5e-28	69.8
AWZ32935.1\|1832231_1832573_-	hypothetical protein	NA	NA	NA	NA
AWZ32936.1\|1832569_1832932_-	hypothetical protein	NA	NA	NA	NA
AWZ33202.1\|1832943_1833135_-	hypothetical protein	NA	NA	NA	NA
AWZ32937.1\|1833258_1833591_-	hypothetical protein	NA	NA	NA	NA
AWZ32938.1\|1833845_1834115_-	phage antirepressor protein	NA	NA	NA	NA
AWZ32939.1\|1834114_1834735_-	phage repressor protein	A0A1W6JPC3	Staphylococcus_phage	1.4e-39	42.3
AWZ32940.1\|1834788_1834950_-	transcriptional regulator	NA	NA	NA	NA
AWZ32941.1\|1835115_1835808_+	transcriptional regulator	A0A0P0IV68	Lactobacillus_phage	4.3e-08	49.2
AWZ32942.1\|1835912_1836122_+	NINE protein	NA	NA	NA	NA
AWZ32943.1\|1836616_1836802_+	hypothetical protein	NA	NA	NA	NA
AWZ32944.1\|1836813_1837155_+	hypothetical protein	A0A1S5SDB5	Streptococcus_phage	2.2e-13	59.7
AWZ32945.1\|1837181_1838147_+	hypothetical protein	A0A0N9RUA4	Staphylococcus_phage	7.1e-86	51.1
AWZ32946.1\|1838479_1839652_+\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	4.3e-154	70.4
1839757:1839776	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1852225 : 1859429

uncultured_Caudovirales_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ32958.1\|1852225_1852930_-	transglycosylase	A0A2H4J6C5	uncultured_Caudovirales_phage	3.2e-27	56.6
AWZ32959.1\|1853035_1853575_-	peptidoglycan-binding protein LysM	A0A249XZV3	Enterococcus_phage	3.0e-17	46.4
AWZ32960.1\|1853790_1854585_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
AWZ32961.1\|1854577_1855420_-	energy-coupling factor transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	2.0e-15	28.5
AWZ32962.1\|1855395_1856235_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	3.5e-20	30.0
AWZ32963.1\|1856234_1856777_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
AWZ32964.1\|1856899_1858183_-	peptidase M16	A0A2H4UVM3	Bodo_saltans_virus	1.6e-05	23.6
AWZ32965.1\|1858184_1859429_-	peptidase M16	A0A1X9I714	Streptococcus_phage	1.7e-87	41.5

DBSCAN-SWA_5

1919449 : 1931514

Microbacterium_phage(14.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ33206.1\|1919449_1923175_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.6e-40	27.0
AWZ33008.1\|1923408_1924863_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	6.3e-54	32.5
AWZ33009.1\|1924890_1925913_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	9.6e-65	44.6
AWZ33010.1\|1926080_1926632_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.8e-25	35.6
AWZ33011.1\|1926651_1927404_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AWZ33012.1\|1927423_1928971_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.5e-77	48.9
AWZ33013.1\|1929163_1930063_+	zoocin A	A0A221J6U0	Arthrobacter_phage	4.1e-19	45.9
AWZ33014.1\|1930209_1931514_+	peptigoglycan-binding protein LysM	A0A2D1GNZ3	Streptomyces_phage	1.7e-05	40.5

Anti-CRISPR protein detection

Acr_ID: CP021771.1|AWZ31304.1|63887_64214_+|replication-initiation-factor

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

CP021771.1|AWZ31304.1|63887_64214_+|replication-initiation-factor

63887_64214_+

108 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|63	1.0	1	1.0

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP021771

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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