CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
CP028431	Escherichia coli strain RM9131 plasmid pRM9131-2, complete sequence	0 crisprs	NA	0	1
CP028429	Escherichia coli strain RM9131 chromosome, complete genome	2 crisprs	DinG,PrimPol,cas3,c2c9_V-U4,DEDDh,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas14i	5	14
CP028430	Escherichia coli strain RM9131 plasmid pRM9131-1, complete sequence	0 crisprs	DEDDh	0	4

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2288 : 38062

Escherichia_phage(36.36%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ55314.1\|2288_3476_-\|transposase	IS91 family transposase	NA	NA	NA	NA
AWZ55315.1\|3475_3841_-\|transposase	transposase	NA	NA	NA	NA
AWZ55316.1\|3979_4234_-	hypothetical protein	NA	NA	NA	NA
AWZ55317.1\|4244_4436_-	hypothetical protein	K7PLX1	Enterobacteria_phage	3.5e-05	41.3
AWZ55318.1\|4740_8706_-	autotransporter outer membrane beta-barrel domain-containing protein	Q9LA58	Enterobacterial_phage	1.1e-230	39.9
AWZ55319.1\|8850_9060_-	hypothetical protein	A0A0N7BTS3	Escherichia_phage	7.8e-06	96.2
AWZ55320.1\|9025_10239_-\|transposase	IS3 family transposase	A0A0N7C035	Escherichia_phage	2.2e-169	100.0
AWZ55321.1\|10878_11274_-	plasmid stabilization protein	NA	NA	NA	NA
AWZ55322.1\|11273_12233_-	plasmid stabilization protein	A0A222YXF2	Escherichia_phage	6.0e-61	40.6
AWZ55380.1\|12505_13408_+	DUF1281 domain-containing protein	NA	NA	NA	NA
AWZ55323.1\|13411_13717_+	hypothetical protein	NA	NA	NA	NA
AWZ55324.1\|13792_14164_+	DNA modification methylase	A0A2I7RE86	Vibrio_phage	1.4e-10	33.9
AWZ55325.1\|14270_15458_-\|transposase	IS91 family transposase	NA	NA	NA	NA
AWZ55326.1\|15457_15823_-\|transposase	transposase	NA	NA	NA	NA
AWZ55327.1\|15750_15936_-	hypothetical protein	NA	NA	NA	NA
AWZ55328.1\|16072_16498_+	antirestriction protein	NA	NA	NA	NA
AWZ55329.1\|16544_16967_+	DUF1380 domain-containing protein	NA	NA	NA	NA
AWZ55330.1\|16963_17155_+	hypothetical protein	NA	NA	NA	NA
AWZ55331.1\|17523_17772_+	hypothetical protein	NA	NA	NA	NA
AWZ55381.1\|17854_17974_+	single-stranded DNA-binding protein	NA	NA	NA	NA
AWZ55332.1\|18192_18423_+	hypothetical protein	NA	NA	NA	NA
AWZ55333.1\|18474_19836_+	DUF3560 domain-containing protein	NA	NA	NA	NA
AWZ55334.1\|20444_20687_+	hypothetical protein	NA	NA	NA	NA
AWZ55383.1\|20596_20857_+	hypothetical protein	NA	NA	NA	NA
AWZ55335.1\|20760_20985_-	hypothetical protein	NA	NA	NA	NA
AWZ55382.1\|20907_21102_+	hypothetical protein	NA	NA	NA	NA
AWZ55336.1\|21028_21265_-	hypothetical protein	NA	NA	NA	NA
AWZ55337.1\|21329_21857_+	single-stranded DNA-binding protein	A0A1B0VAF5	Salmonella_phage	4.6e-47	54.1
AWZ55338.1\|21912_22146_+	DUF905 domain-containing protein	A0A096XUX0	Cronobacter_phage	3.9e-06	51.1
AWZ55339.1\|22204_24163_+	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	6.6e-22	29.9
AWZ55340.1\|24217_24652_+	conjugation system SOS inhibitor PsiB	NA	NA	NA	NA
AWZ55341.1\|24648_25368_+	plasmid SOS inhibition protein A	NA	NA	NA	NA
AWZ55342.1\|25647_25806_+	protein hok	NA	NA	NA	NA
AWZ55343.1\|26025_26256_+	hypothetical protein	NA	NA	NA	NA
AWZ55384.1\|26306_26495_+	hypothetical protein	NA	NA	NA	NA
AWZ55344.1\|26496_26703_+	single-stranded DNA-binding protein	NA	NA	NA	NA
AWZ55345.1\|26727_27015_+	hypothetical protein	NA	NA	NA	NA
AWZ55346.1\|27024_27957_+	DUF945 domain-containing protein	A0A2C9CYF8	Yersinia_phage	3.8e-44	38.2
AWZ55347.1\|29176_29560_+	conjugal transfer protein TraM	NA	NA	NA	NA
AWZ55348.1\|29746_30436_+	conjugal transfer protein TraJ	NA	NA	NA	NA
AWZ55385.1\|30534_30930_+	relaxosome protein TraY	NA	NA	NA	NA
AWZ55349.1\|30962_31322_+	pilin	NA	NA	NA	NA
AWZ55350.1\|31336_31648_+	type IV conjugative transfer system protein TraL	NA	NA	NA	NA
AWZ55351.1\|31669_32236_+	type IV conjugative transfer system protein TraE	NA	NA	NA	NA
AWZ55386.1\|32279_32951_+	type-F conjugative transfer system secretin TraK	NA	NA	NA	NA
AWZ55352.1\|32950_34378_+	conjugal transfer protein TraB	NA	NA	NA	NA
AWZ55353.1\|34367_34958_+	conjugal transfer protein TraP	NA	NA	NA	NA
AWZ55354.1\|34944_35067_+	conjugal transfer protein TrbD	NA	NA	NA	NA
AWZ55355.1\|36848_38062_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP028429

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CRISPR-Cas detection and classification

Crispr_ID: CP028429_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028429_1

3304864-3305197

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder

5 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of CP028429_1

>merge|CP028429|1|3304864-3305197|CRT,PILER-CR,CRISPRCasFinder
GGGAGTTCTACCGCAGGGGCGGGGAATTCTAAGTGATATCCATCATCGCATCCAGTGCGCCCGGTTTATCCCCGCTGACGCGGGGAACACAAAACCAAACTTCTCCATAAATTCCATAGCCGCGGTTTATCCCCGCTGGCGCGGGGAACACGAGAGTGCTGACAGGTGTCTCGATTACCTGATCGGTTTATCCCCGCTGGCGCGGGGAACACGAACGCAATATCACGGCGTTCTGCGGCCTCGGCGGTTTATCCCCGCTGGCGCGGGGAACACGTCGGGCCGGGTAAGTGAACCTGTCGGTTTTCCGGTTTATCCCCGCTGGCGCGGGGAACAC

>CP028429|1|1|3304864-3305197|CRT
GGGAGTTCTACCGCAGGGGCGGGGAATTC	TAAGTGATATCCATCATCGCATCCAGTGCGCC
CGGTTTATCCCCGCTGACGCGGGGAACAC	AAAACCAAACTTCTCCATAAATTCCATAGCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAGAGTGCTGACAGGTGTCTCGATTACCTGAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAACGCAATATCACGGCGTTCTGCGGCCTCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCGGGCCGGGTAAGTGAACCTGTCGGTTTTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>CP028429|1|1|3304925-3305197|PILER-CR
CGGTTTATCCCCGCTGACGCGGGGAACAC	AAAACCAAACTTCTCCATAAATTCCATAGCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAGAGTGCTGACAGGTGTCTCGATTACCTGAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAACGCAATATCACGGCGTTCTGCGGCCTCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCGGGCCGGGTAAGTGAACCTGTCGGTTTTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>CP028429|1|1|3304925-3305197|CRISPRCasFinder
CGGTTTATCCCCGCTGACGCGGGGAACAC	AAAACCAAACTTCTCCATAAATTCCATAGCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAGAGTGCTGACAGGTGTCTCGATTACCTGAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAACGCAATATCACGGCGTTCTGCGGCCTCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCGGGCCGGGTAAGTGAACCTGTCGGTTTTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
CP028429.1\|AWZ53192.1\|3299004_3299715_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
CP028429.1\|AWZ53196.1\|3301216_3302644_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
CP028429.1\|AWZ53193.1\|3299733_3300045_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
CP028429.1\|AWZ53205.1\|3309495_3311058_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
CP028429.1\|AWZ53199.1\|3305293_3305587_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
CP028429.1\|AWZ53202.1\|3307135_3307882_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
CP028429.1\|AWZ53189.1\|3296737_3297499_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
CP028429.1\|AWZ53194.1\|3300238_3300562_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371891
CP028429.1\|AWZ53206.1\|3311155_3313855_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
CP028429.1\|AWZ53197.1\|3302645_3303554_-\|sulfate-adenylyltransferase-subunit-2	unknown	unknown	gnl\|CDD\|235375
CP028429.1\|AWZ53204.1\|3308959_3309499_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
CP028429.1\|AWZ53200.1\|3305586_3306507_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
CP028429.1\|AWZ53191.1\|3298525_3299005_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
CP028429.1\|AWZ53207.1\|3314048_3314201_-\|Hok/Gef-family-protein	unknown	unknown	gnl\|CDD\|366840
CP028429.1\|AWZ53195.1\|3300611_3301217_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
CP028429.1\|AWZ53190.1\|3297479_3298529_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
CP028429.1\|AWZ53203.1\|3307892_3308948_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
CP028429.1\|AWZ53198.1\|3303805_3304843_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
CP028429.1\|AWZ53201.1\|3306503_3307154_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
CP028429.1\|AWZ53208.1\|3314465_3315200_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997

Protein	Function_ID	Function_description	E-value
CP028429.1\|AWZ53192.1\|3299004_3299715_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
CP028429.1\|AWZ53196.1\|3301216_3302644_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
CP028429.1\|AWZ53193.1\|3299733_3300045_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
CP028429.1\|AWZ53205.1\|3309495_3311058_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
CP028429.1\|AWZ53199.1\|3305293_3305587_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
CP028429.1\|AWZ53202.1\|3307135_3307882_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	3.02728e-49
CP028429.1\|AWZ53189.1\|3296737_3297499_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
CP028429.1\|AWZ53194.1\|3300238_3300562_-\|hypothetical-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
CP028429.1\|AWZ53206.1\|3311155_3313855_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	6.73288e-179
CP028429.1\|AWZ53197.1\|3302645_3303554_-\|sulfate-adenylyltransferase-subunit-2	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
CP028429.1\|AWZ53204.1\|3308959_3309499_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	7.30002e-26
CP028429.1\|AWZ53200.1\|3305586_3306507_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	4.23259e-157
CP028429.1\|AWZ53191.1\|3298525_3299005_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
CP028429.1\|AWZ53207.1\|3314048_3314201_-\|Hok/Gef-family-protein	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
CP028429.1\|AWZ53195.1\|3300611_3301217_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
CP028429.1\|AWZ53190.1\|3297479_3298529_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
CP028429.1\|AWZ53203.1\|3307892_3308948_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	6.10696e-155
CP028429.1\|AWZ53198.1\|3303805_3304843_+\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
CP028429.1\|AWZ53201.1\|3306503_3307154_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	7.04911e-92
CP028429.1\|AWZ53208.1\|3314465_3315200_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.99311e-138

>CP028429.1|AWZ53198.1|3303805_3304843_+|aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTPAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>CP028429.1|AWZ53197.1|3302645_3303554_-|sulfate-adenylyltransferase-subunit-2
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>CP028429.1|AWZ53196.1|3301216_3302644_-|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTSGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>CP028429.1|AWZ53195.1|3300611_3301217_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>CP028429.1|AWZ53194.1|3300238_3300562_-|hypothetical-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>CP028429.1|AWZ53193.1|3299733_3300045_-|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>CP028429.1|AWZ53192.1|3299004_3299715_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>CP028429.1|AWZ53191.1|3298525_3299005_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>CP028429.1|AWZ53190.1|3297479_3298529_-|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEYILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLNDICVKGVPNYFGAQRFGIGGSNLQGARRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>CP028429.1|AWZ53189.1|3296737_3297499_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW
>CP028429.1|AWZ53199.1|3305293_3305587_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>CP028429.1|AWZ53200.1|3305586_3306507_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPQPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRG
>CP028429.1|AWZ53201.1|3306503_3307154_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESDTFTIECRSFAPELCTGQQLCFNLRANPTICKAGKRHDLLMEAKRQVRGQAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFVQRLSQGYGKSRAFGCGLMLIKPGAEA
>CP028429.1|AWZ53202.1|3307135_3307882_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGGDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPELLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNACDALCNAYQQYQDHFHKLKVSLPKLQDECWWEGKHDGLVASKILRRRDVPLNRQQWLFGERTVNQGAWLSKEEPCTSQE
>CP028429.1|AWZ53203.1|3307892_3308948_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEDKKAIEWSAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>CP028429.1|AWZ53204.1|3308959_3309499_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWREELQAKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKIEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRAVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQNQ
>CP028429.1|AWZ53205.1|3309495_3311058_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGTAWQFLLGLLQTSFAPKNHGRWDDIWQDGLEAEKLREALLSLEHAFQFGADSPSFMQDFEALKGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCPHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWPNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTHDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDALLSLMTTKNYGANYAMWQHPLTPYRIPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLKKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLGKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>CP028429.1|AWZ53206.1|3311155_3313855_-|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKNRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGQPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIESPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAHPMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQQKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKYCSLQRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDSPGDEWFGSAMRNSAFVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRLWCIEQRQDPEMANVILVNDDESCGYSATEGLIGKVG
>CP028429.1|AWZ53207.1|3314048_3314201_-|Hok/Gef-family-protein
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>CP028429.1|AWZ53208.1|3314465_3315200_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG

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Crispr_ID: CP028429_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028429_2

3330899-3331293

Unclear

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAAC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACA	PILER-CR

6 spacers

The CRISPR arrays of CP028429_2

>merge|CP028429|2|3330899-3331293|CRISPRCasFinder,CRT,PILER-CR
TGGTTTATCCCCGCTGGCGCGGGGAACTCGACAGAACGGCCTCAGTAGTCTCGTCAGGCTCCGGTTTATCCCCGCTGGCGCGGGGAGCTCTACGTGAAGAATATTTGCAACACCCGCAAGAACGGTTTATCCCCGCTGGCGCGGGGAACACTCCAACCTTCCATGAGATACGCGCATTAGCGGCGGTTTATCCCCGCTGGCGCGGGGAACACCGTGACCGCCTGTACACGCTGTAATGGCTCACCGGTTTATCCCCGCTGGCGCGGGGAACACACACTATCCGGGCGGTATTACGCCCAAATATCCGGTTTATCCCCGCTGGCGCGGGGAACACCTGCCGGGTGAAACCACTCGCGGCAGATCTTGCGGTTTATCCCCGCTGGCGCGGGGAACAC

>CP028429|2|2|3330899-3331293|CRISPRCasFinder
TGGTTTATCCCCGCTGGCGCGGGGAACTC	GACAGAACGGCCTCAGTAGTCTCGTCAGGCTC
CGGTTTATCCCCGCTGGCGCGGGGAGCTC	TACGTGAAGAATATTTGCAACACCCGCAAGAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCCAACCTTCCATGAGATACGCGCATTAGCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGTGACCGCCTGTACACGCTGTAATGGCTCAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACACTATCCGGGCGGTATTACGCCCAAATATC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CTGCCGGGTGAAACCACTCGCGGCAGATCTTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>CP028429|2|2|3330899-3331291|CRT
TGGTTTATCCCCGCTGGCGCGGGGAAC	TCGACAGAACGGCCTCAGTAGTCTCGTCAGGCTC
CGGTTTATCCCCGCTGGCGCGGGGAGC	TCTACGTGAAGAATATTTGCAACACCCGCAAGAA
CGGTTTATCCCCGCTGGCGCGGGGAAC	ACTCCAACCTTCCATGAGATACGCGCATTAGCGG
CGGTTTATCCCCGCTGGCGCGGGGAAC	ACCGTGACCGCCTGTACACGCTGTAATGGCTCAC
CGGTTTATCCCCGCTGGCGCGGGGAAC	ACACACTATCCGGGCGGTATTACGCCCAAATATC
CGGTTTATCCCCGCTGGCGCGGGGAAC	ACCTGCCGGGTGAAACCACTCGCGGCAGATCTTG
CGGTTTATCCCCGCTGGCGCGGGGAAC

>CP028429|2|2|3330960-3331292|PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAGCT	CTACGTGAAGAATATTTGCAACACCCGCAAGAACGG
TTTATCCCCGCTGGCGCGGGGAACACTC	CAACCTTCCATGAGATACGCGCATTAGCGGCGG
TTTATCCCCGCTGGCGCGGGGAACACCG	TGACCGCCTGTACACGCTGTAATGGCTCACCGG
TTTATCCCCGCTGGCGCGGGGAACACAC	ACTATCCGGGCGGTATTACGCCCAAATATCCGG
TTTATCCCCGCTGGCGCGGGGAACACCT	GCCGGGTGAAACCACTCGCGGCAGATCTTGCGG
TTTATCCCCGCTGGCGCGGGGAACA

Protein	Signature genes	Signature genes Name	Protein_function
CP028429.1\|AWZ53215.1\|3321805_3322666_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
CP028429.1\|AWZ53225.1\|3333528_3334827_-\|enolase	unknown	unknown	gnl\|CDD\|234617
CP028429.1\|AWZ53227.1\|3336779_3337571_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
CP028429.1\|AWZ53219.1\|3326374_3327160_-\|KR-domain-containing-protein	unknown	unknown	gnl\|CDD\|187605
CP028429.1\|AWZ53221.1\|3328781_3330260_+\|sugar-kinase	unknown	unknown	gnl\|CDD\|212662
CP028429.1\|AWZ53214.1\|3321082_3321658_+\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
CP028429.1\|AWZ53224.1\|3332596_3333469_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224429
CP028429.1\|AWZ53220.1\|3327478_3328756_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
CP028429.1\|AWZ53230.1\|3338302_3340537_-\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
CP028429.1\|AWZ53222.1\|3331632_3332304_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
CP028429.1\|AWZ53216.1\|3322662_3323442_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
CP028429.1\|AWZ53231.1\|3341941_3344698_+\|signal-transduction-histidine-kinase	unknown	unknown	gnl\|CDD\|236848
CP028429.1\|AWZ53218.1\|3324850_3326305_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
CP028429.1\|AWZ53217.1\|3323419_3324757_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
CP028429.1\|AWZ53223.1\|3332442_3332583_+\|hypothetical-protein	unknown	unknown	unknown
CP028429.1\|AWZ53228.1\|3337641_3337977_-\|toxin-MazF	unknown	unknown	gnl\|CDD\|182138
CP028429.1\|AWZ53226.1\|3334914_3336552_-\|CTP-synthetase	unknown	unknown	gnl\|CDD\|235437
CP028429.1\|AWZ53213.1\|3320805_3321066_+\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
CP028429.1\|AWZ53212.1\|3319543_3320815_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
CP028429.1\|AWZ53229.1\|3337976_3338225_-\|antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082

Protein	Function_ID	Function_description	E-value
CP028429.1\|AWZ53215.1\|3321805_3322666_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	5.55254e-89
CP028429.1\|AWZ53225.1\|3333528_3334827_-\|enolase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
CP028429.1\|AWZ53227.1\|3336779_3337571_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
CP028429.1\|AWZ53219.1\|3326374_3327160_-\|KR-domain-containing-protein	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.61186e-139
CP028429.1\|AWZ53221.1\|3328781_3330260_+\|sugar-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	1.84635e-108
CP028429.1\|AWZ53214.1\|3321082_3321658_+\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
CP028429.1\|AWZ53224.1\|3332596_3333469_+\|hypothetical-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.01855e-100
CP028429.1\|AWZ53220.1\|3327478_3328756_+\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	3.54023e-29
CP028429.1\|AWZ53230.1\|3338302_3340537_-\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
CP028429.1\|AWZ53222.1\|3331632_3332304_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.73859e-155
CP028429.1\|AWZ53216.1\|3322662_3323442_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	3.2021e-62
CP028429.1\|AWZ53231.1\|3341941_3344698_+\|signal-transduction-histidine-kinase	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	0
CP028429.1\|AWZ53218.1\|3324850_3326305_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.25325e-82
CP028429.1\|AWZ53217.1\|3323419_3324757_-\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.74708e-50
CP028429.1\|AWZ53228.1\|3337641_3337977_-\|toxin-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	2.42227e-74
CP028429.1\|AWZ53226.1\|3334914_3336552_-\|CTP-synthetase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
CP028429.1\|AWZ53213.1\|3320805_3321066_+\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	8.55479e-42
CP028429.1\|AWZ53212.1\|3319543_3320815_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	3.03384e-127
CP028429.1\|AWZ53229.1\|3337976_3338225_-\|antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48

>CP028429.1|AWZ53221.1|3328781_3330260_+|sugar-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPYADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASSVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA
>CP028429.1|AWZ53220.1|3327478_3328756_+|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEVRTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALAMVIVFTFLLFQKIRTADSAPAMASSK
>CP028429.1|AWZ53219.1|3326374_3327160_-|KR-domain-containing-protein
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDSMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>CP028429.1|AWZ53218.1|3324850_3326305_-|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>CP028429.1|AWZ53217.1|3323419_3324757_-|MFS-transporter
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>CP028429.1|AWZ53216.1|3322662_3323442_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRIEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>CP028429.1|AWZ53215.1|3321805_3322666_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGAVKNATLPSGMQQLNIVPGALPDWLVSTEDLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ
>CP028429.1|AWZ53214.1|3321082_3321658_+|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>CP028429.1|AWZ53213.1|3320805_3321066_+|ferredoxin-family-protein
MSVAHNLWRVADAPHIVPADSVERQMVQRLINACPAGLFSLTPEGDLRVDYHGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>CP028429.1|AWZ53212.1|3319543_3320815_+|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHELAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEEEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLEPSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFALYHHNVERSLLWDVLQRYQHVPALLQRPGWYRAWPALMQDISRDLWDQGDKPVPPLRQLFWRHLRRHGLWHLAGDVIRSLRCL
>CP028429.1|AWZ53222.1|3331632_3332304_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>CP028429.1|AWZ53223.1|3332442_3332583_+|hypothetical-protein
MSEENKENGFNHVKTFTKIIFIFSVLVFNDDESKITDAAVNLFIQI
>CP028429.1|AWZ53224.1|3332596_3333469_+|hypothetical-protein
MRYFILMFTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKELTHKLESIFNNTQVQIAVLIVPTTKDETIEQYATRVFDNWRLGDAKRNDGILIIVAWSDRTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKFAQGLELAINALNNQLTSQHQYPTNPSESESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSGVYISAIYLLDLFLFSDKIFSIAVFSFFFTFTIFMVFTCLCVLQKRASGKSYHSDNSGSGGGSSGGGFSGGGGSSGGGGASGRW
>CP028429.1|AWZ53225.1|3333528_3334827_-|enolase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>CP028429.1|AWZ53226.1|3334914_3336552_-|CTP-synthetase
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>CP028429.1|AWZ53227.1|3336779_3337571_-|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>CP028429.1|AWZ53228.1|3337641_3337977_-|toxin-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPYTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>CP028429.1|AWZ53229.1|3337976_3338225_-|antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>CP028429.1|AWZ53230.1|3338302_3340537_-|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>CP028429.1|AWZ53231.1|3341941_3344698_+|signal-transduction-histidine-kinase
MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFHLDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYIALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYSPTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPEVNEIVMNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREASKILG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP028429_1	1.1\|3304893\|32\|CP028429\|CRT	3304893-3304924	32	LC542972	Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence	246937-246968	3	0.906
CP028429_1	1.2\|3304954\|32\|CP028429\|CRT,PILER-CR,CRISPRCasFinder	3304954-3304985	32	NZ_CP050442	Tolypothrix sp. PCC 7910 plasmid unnamed2, complete sequence	41503-41534	6	0.812
CP028429_1	1.1\|3304893\|32\|CP028429\|CRT	3304893-3304924	32	NZ_CP015038	Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence	112768-112799	7	0.781
CP028429_1	1.1\|3304893\|32\|CP028429\|CRT	3304893-3304924	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1428097-1428128	8	0.75
CP028429_2	2.1\|3330928\|32\|CP028429\|CRISPRCasFinder	3330928-3330959	32	MK814759	Gordonia phage Reyja, complete genome	4467-4498	8	0.75
CP028429_1	1.1\|3304893\|32\|CP028429\|CRT	3304893-3304924	32	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	141278-141309	9	0.719
CP028429_1	1.3\|3305015\|32\|CP028429\|CRT,PILER-CR,CRISPRCasFinder	3305015-3305046	32	LT599585	Pseudomonas veronii 1YdBTEX2 genome assembly, plasmid: PVE_plasmid	32377-32408	9	0.719
CP028429_1	1.4\|3305076\|32\|CP028429\|CRT,PILER-CR,CRISPRCasFinder	3305076-3305107	32	NC_010553	Burkholderia ambifaria MC40-6 plasmid pBMC401, complete sequence	292180-292211	9	0.719
CP028429_1	1.4\|3305076\|32\|CP028429\|CRT,PILER-CR,CRISPRCasFinder	3305076-3305107	32	NZ_CP020740	[Pseudomonas] mesoacidophila strain ATCC 31433 plasmid pATCC31433, complete sequence	20747-20778	9	0.719

1. spacer 1.1|3304893|32|CP028429|CRT matches to LC542972 (Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence) position: , mismatch: 3, identity: 0.906

taagtgatatccatcatcgcatccagtgcgcc	CRISPR spacer
caagtgatgtccatcatcgcatccagtgcgtc	Protospacer
.*******.*********************.*

2. spacer 1.2|3304954|32|CP028429|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP050442 (Tolypothrix sp. PCC 7910 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.812

aaaaccaaacttctccataaattccatagccg	CRISPR spacer
attactaaacttctgcataaattccataggag	Protospacer
*  **.******** **************  *

3. spacer 1.1|3304893|32|CP028429|CRT matches to NZ_CP015038 (Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence) position: , mismatch: 7, identity: 0.781

taagtgat-atccatcatcgcatccagtgcgcc	CRISPR spacer
-ggttgatcgtccttcatcgcagccagtgcgcc	Protospacer
 .. **** .*** ******** **********

4. spacer 1.1|3304893|32|CP028429|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.75

taagtg---atatccatcatcgcatccagtgcgcc	CRISPR spacer
---gtgcgcccctccatcaccgcttccagtgcgcc	Protospacer
   ***    . *******.*** ***********

5. spacer 2.1|3330928|32|CP028429|CRISPRCasFinder matches to MK814759 (Gordonia phage Reyja, complete genome) position: , mismatch: 8, identity: 0.75

-gacagaacggcctcagtagtctcgtcaggctc	CRISPR spacer
ccaccg-ctggccccagtagcctcgtcaggctt	Protospacer
  ** *  .****.******.***********.

6. spacer 1.1|3304893|32|CP028429|CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 9, identity: 0.719

taagtgatatccatcatcgcatccagtgcgcc	CRISPR spacer
ctcatcgcatccatcatcggttccagtgcgcc	Protospacer
.  .* ..***********  ***********

7. spacer 1.3|3305015|32|CP028429|CRT,PILER-CR,CRISPRCasFinder matches to LT599585 (Pseudomonas veronii 1YdBTEX2 genome assembly, plasmid: PVE_plasmid) position: , mismatch: 9, identity: 0.719

gagagtgctgacaggtgtctcgattacctgat	CRISPR spacer
ggctttgctggcaggtctctcgattaccttgg	Protospacer
*.   *****.***** ************ .

8. spacer 1.4|3305076|32|CP028429|CRT,PILER-CR,CRISPRCasFinder matches to NC_010553 (Burkholderia ambifaria MC40-6 plasmid pBMC401, complete sequence) position: , mismatch: 9, identity: 0.719

gaacgcaatatcacggcgttctgcggcctcgg	CRISPR spacer
atcggcaatatcacggcgtttttcggcgccgc	Protospacer
.   ****************.* **** .**

9. spacer 1.4|3305076|32|CP028429|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP020740 ([Pseudomonas] mesoacidophila strain ATCC 31433 plasmid pATCC31433, complete sequence) position: , mismatch: 9, identity: 0.719

gaacgcaatatcacggcgttctgcggcctcgg	CRISPR spacer
accggcaacatcacggcgttcttcggcgccgc	Protospacer
.   ****.************* **** .**

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

326300 : 336628

Enterobacteria_phage(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ50372.1\|326300_327356_-	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	7.0e-119	61.1
AWZ50373.1\|327643_328747_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-61	40.4
AWZ50374.1\|328758_330012_+	gamma-glutamyl-phosphate reductase	A0A1X9I5D4	Streptococcus_phage	1.7e-95	47.0
AWZ50375.1\|330367_331582_+	DUF4102 domain-containing protein	Q7M297	Enterobacteria_phage	7.5e-133	56.5
AWZ50376.1\|331724_332606_+	hypothetical protein	NA	NA	NA	NA
AWZ50377.1\|332803_333001_+	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	1.7e-07	48.1
AWZ50378.1\|333000_333432_+	hypothetical protein	A0A1W6JPH9	Morganella_phage	5.1e-28	49.0
AWZ50379.1\|333444_333840_+	hypothetical protein	A0A139ZPI9	Marinitoga_camini_virus	2.1e-07	36.6
AWZ50380.1\|333865_335078_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ50381.1\|335044_335308_+	hypothetical protein	A0A0N7BTS3	Escherichia_phage	3.4e-06	75.7
AWZ50382.1\|335557_336628_+	DNA (cytosine-5-)-methyltransferase	A0A1B1IRZ3	uncultured_Mediterranean_phage	2.6e-20	29.6

DBSCAN-SWA_2

550426 : 630318

Escherichia_phage(33.33%)

capsid,transposase,protease,head,tRNA,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ50582.1\|550426_550906_-\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
AWZ50583.1\|550921_551200_-	hypothetical protein	NA	NA	NA	NA
AWZ50584.1\|551109_551904_-	hypothetical protein	NA	NA	NA	NA
AWZ50585.1\|552041_552383_+	addiction module antidote protein, HigA family	A0A222YWD7	Escherichia_phage	2.1e-40	74.5
AWZ50586.1\|552496_555001_-	copper-exporting P-type ATPase CopA	A0A218MNH6	uncultured_virus	3.8e-115	38.4
AWZ50587.1\|555262_556195_+	glutaminase	NA	NA	NA	NA
AWZ50588.1\|556197_557490_+	amino acid permease	NA	NA	NA	NA
AWZ50589.1\|557614_558022_+	transcriptional regulator	NA	NA	NA	NA
AWZ50590.1\|558022_558481_-	NfeD family protein	NA	NA	NA	NA
AWZ50591.1\|558477_559395_-	paraslipin	NA	NA	NA	NA
AWZ50592.1\|559540_560218_+	iron ABC transporter ATP-binding protein FetA	G3M9Y6	Bacillus_virus	3.1e-27	33.8
AWZ50593.1\|560204_560987_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
AWZ50594.1\|561049_561904_-	co-chaperone YbbN	NA	NA	NA	NA
AWZ50595.1\|561964_562774_-	oxidoreductase	NA	NA	NA	NA
AWZ50596.1\|562763_563390_-	arylesterase	NA	NA	NA	NA
AWZ50597.1\|563357_564044_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.9e-33	35.6
AWZ50598.1\|564040_566455_+	ABC transporter permease	NA	NA	NA	NA
AWZ50599.1\|571076_571337_+	hypothetical protein	NA	NA	NA	NA
AWZ50600.1\|571375_571567_+	hypothetical protein	NA	NA	NA	NA
AWZ50601.1\|572568_573663_-\|tRNA	tRNA 2-selenouridine(34) synthase MnmH	NA	NA	NA	NA
AWZ50602.1\|573731_574658_-	HTH-type transcriptional activator AllS	NA	NA	NA	NA
AWZ50603.1\|574887_575370_+	ureidoglycolate lyase	NA	NA	NA	NA
AWZ50604.1\|575447_576263_+	transcriptional regulator	NA	NA	NA	NA
AWZ50605.1\|576352_578134_+	glyoxylate carboligase	E4WLQ6	Ostreococcus_tauri_virus	7.8e-38	27.0
AWZ50606.1\|578146_578923_+	hydroxypyruvate isomerase	NA	NA	NA	NA
AWZ50607.1\|579022_579901_+	2-hydroxy-3-oxopropionate reductase	NA	NA	NA	NA
AWZ50608.1\|580069_581524_+	putative allantoin permease	NA	NA	NA	NA
AWZ50609.1\|581583_582945_+	cyclic amidohydrolase	NA	NA	NA	NA
AWZ50610.1\|583001_584303_+	uracil/xanthine transporter	NA	NA	NA	NA
AWZ50611.1\|584324_585470_+	glycerate kinase	W6LM47	Streptococcus_phage	1.1e-48	41.9
AWZ50612.1\|585598_586384_-	(S)-ureidoglycine aminohydrolase	NA	NA	NA	NA
AWZ50613.1\|586394_587630_-	allantoate amidohydrolase	NA	NA	NA	NA
AWZ50614.1\|587651_588701_-	ureidoglycolate dehydrogenase	NA	NA	NA	NA
AWZ50615.1\|589017_590685_+	acyl-CoA synthetase FdrA	NA	NA	NA	NA
AWZ50616.1\|590694_591954_+	DUF1116 domain-containing protein	NA	NA	NA	NA
AWZ50617.1\|591964_592780_+	DUF2877 domain-containing protein	NA	NA	NA	NA
AWZ50618.1\|592776_593670_+	carbamate kinase	NA	NA	NA	NA
AWZ50619.1\|593806_594874_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
AWZ50620.1\|594870_595380_-	5-(carboxyamino)imidazole ribonucleotide mutase	NA	NA	NA	NA
AWZ50621.1\|595497_596220_-	UDP-2,3-diacylglucosamine hydrolase	NA	NA	NA	NA
AWZ50622.1\|596222_596717_-	peptidylprolyl isomerase	NA	NA	NA	NA
AWZ50623.1\|596890_598276_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	3.0e-45	34.8
AWZ50624.1\|598311_598833_-	metal-dependent hydrolase	NA	NA	NA	NA
AWZ50625.1\|598940_599153_-	ribosome-associated protein	NA	NA	NA	NA
AWZ50626.1\|599154_600021_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	1.7e-30	37.5
AWZ50627.1\|600501_601044_+	type 1 fimbrial protein subunit FimA	NA	NA	NA	NA
AWZ50628.1\|601263_601956_+	molecular chaperone FimC	NA	NA	NA	NA
AWZ50629.1\|601986_604596_+	outer membrane usher protein	NA	NA	NA	NA
AWZ50630.1\|605647_606163_+	fimbriae assembly protein	NA	NA	NA	NA
AWZ50631.1\|606165_606798_-	DNA-binding response regulator	NA	NA	NA	NA
AWZ50632.1\|608008_608341_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	5.0e-55	99.1
AWZ50633.1\|608396_609422_+\|capsid	minor capsid protein E	C6ZCY2	Enterobacteria_phage	3.1e-188	97.4
AWZ50634.1\|609463_609859_+	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	5.7e-58	95.5
AWZ50635.1\|609870_610170_+\|tail	phage tail protein	A0A2R9YJJ5	Escherichia_phage	8.4e-46	98.9
AWZ50636.1\|610190_611403_+\|transposase	IS3 family transposase	Q716C2	Shigella_phage	8.3e-100	57.1
AWZ50637.1\|611496_612075_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	1.3e-79	99.0
AWZ50638.1\|612071_612467_+\|tail	phage tail protein	A0A0K2FIF4	Enterobacteria_phage	1.4e-69	98.5
AWZ54978.1\|612474_613215_+\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	1.0e-129	98.0
AWZ50639.1\|613230_613653_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	3.1e-70	96.4
AWZ50640.1\|613634_614069_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
AWZ50641.1\|614061_616242_+\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	90.7
AWZ50642.1\|616247_617460_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ54977.1\|617530_618157_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
AWZ50643.1\|618255_618561_+\|tail	phage tail protein	K7PMH7	Enterobacteria_phage	2.8e-12	76.5
AWZ50644.1\|618744_620229_-	alpha/beta hydrolase	NA	NA	NA	NA
AWZ50645.1\|620415_621369_-\|protease	protease 7	NA	NA	NA	NA
AWZ50646.1\|621394_621586_+	hypothetical protein	NA	NA	NA	NA
AWZ50647.1\|621771_621888_-	hypothetical protein	NA	NA	NA	NA
AWZ50648.1\|621881_622643_-	AraC family transcriptional regulator	NA	NA	NA	NA
AWZ50649.1\|622699_622912_+	hypothetical protein	NA	NA	NA	NA
AWZ50650.1\|622825_623716_-	hypothetical protein	NA	NA	NA	NA
AWZ50651.1\|623716_626689_-	phage receptor	NA	NA	NA	NA
AWZ50652.1\|626675_628913_-	phage adsorption protein NrfB	NA	NA	NA	NA
AWZ50653.1\|629181_630318_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

849743 : 869068

Enterobacteria_phage(54.55%)

transposase,holin,integrase

attL 854983:854997|attR 868384:868398

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ50852.1\|849743_850820_-\|integrase	integrase	K7P6P6	Enterobacteria_phage	1.8e-199	99.4
AWZ50853.1\|850833_851244_-	lysozyme	A0A0N7KZA0	Stx2-converting_phage	1.1e-64	99.2
AWZ50854.1\|852529_852820_+	hypothetical protein	K7PH23	Enterobacteria_phage	2.5e-50	100.0
AWZ50855.1\|853116_853479_+	hypothetical protein	A0A2I6PIG0	Escherichia_phage	4.4e-33	67.9
AWZ50856.1\|853450_853861_+	recombination protein NinB	A0A0P0ZCW6	Stx2-converting_phage	2.1e-71	98.5
AWZ50857.1\|853857_854034_+	NinE family protein	A5VW90	Enterobacteria_phage	4.6e-28	100.0
AWZ50858.1\|854036_854396_+	DUF2591 domain-containing protein	G8EYI2	Enterobacteria_phage	2.7e-62	95.0
AWZ50859.1\|854395_854572_+	protein ninF	A0A220NRM2	Escherichia_phage	1.9e-26	100.0
AWZ50860.1\|854564_854777_+	hypothetical protein	K7PK10	Enterobacteria_phage	1.6e-35	100.0
AWZ50861.1\|854769_855060_+	DUF1364 domain-containing protein	K7PK25	Enterobacteria_phage	7.1e-50	97.9
854983:854997	attL	NA	NA	NA	NA
AWZ50862.1\|855056_855419_+	RusA family crossover junction endodeoxyribonuclease	A5VW85	Enterobacteria_phage	3.5e-62	98.3
AWZ50863.1\|855415_855604_+	protein ninH	A5VW84	Enterobacteria_phage	5.5e-27	100.0
AWZ50864.1\|855815_856775_-	DUF2219 domain-containing protein	NA	NA	NA	NA
AWZ50865.1\|857114_857237_+	YlcG family protein	NA	NA	NA	NA
AWZ50866.1\|857251_857941_+	antitermination protein	I6PDF8	Cronobacter_phage	1.5e-58	48.1
AWZ50867.1\|858152_858869_+	hypothetical protein	NA	NA	NA	NA
AWZ50868.1\|858954_859113_+	DUF3927 domain-containing protein	NA	NA	NA	NA
AWZ50869.1\|859411_861262_+	DUF1737 domain-containing protein	B6DZ89	Enterobacteria_phage	0.0e+00	95.9
AWZ50870.1\|861540_861702_-	hypothetical protein	NA	NA	NA	NA
AWZ50871.1\|861700_861916_+\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	1.7e-32	97.2
AWZ50872.1\|861915_862104_+	lysozyme	A0A0N7KZA0	Stx2-converting_phage	1.9e-19	100.0
AWZ50873.1\|862106_863320_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ50874.1\|863373_863577_+	hypothetical protein	A0A1I9LJT0	Stx_converting_phage	1.4e-28	97.0
AWZ50875.1\|863682_864564_+	T3SS effector protein NleH	A5LH48	Enterobacteria_phage	3.9e-147	90.4
AWZ50876.1\|864787_865618_+	cell division protein	A5LH49	Enterobacteria_phage	7.6e-153	97.8
AWZ50877.1\|865741_866113_-\|integrase	integrase	K7PH54	Enterobacteria_phage	1.1e-58	95.1
AWZ50878.1\|867331_867712_+	hypothetical protein	NA	NA	NA	NA
AWZ50879.1\|867855_869068_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
868384:868398	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1079722 : 1122281

Escherichia_phage(37.93%)

protease,lysis,transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ51057.1\|1079722_1081483_-\|protease	Lon protease	NA	NA	NA	NA
AWZ51058.1\|1081668_1082121_+	macrodomain Ter protein	NA	NA	NA	NA
AWZ54990.1\|1082196_1083237_-	outer membrane protein A	NA	NA	NA	NA
AWZ51059.1\|1083391_1083610_+	hypothetical protein	NA	NA	NA	NA
AWZ51060.1\|1083593_1084103_-	cell division inhibitor SulA	NA	NA	NA	NA
AWZ51061.1\|1084375_1084951_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
AWZ54991.1\|1084913_1087067_-	TIGR01666 family membrane protein	NA	NA	NA	NA
AWZ51062.1\|1087085_1087532_-	YccF domain-containing protein	NA	NA	NA	NA
AWZ51063.1\|1087654_1089709_+	DNA helicase IV	A7KV33	Bacillus_phage	7.7e-21	27.9
AWZ51064.1\|1089740_1090199_-	methylglyoxal synthase	NA	NA	NA	NA
AWZ51065.1\|1090294_1090957_-	DUF2057 domain-containing protein	NA	NA	NA	NA
AWZ51066.1\|1091129_1091543_+	CoA-binding protein	NA	NA	NA	NA
AWZ51067.1\|1091587_1091905_-	heat-shock protein HspQ	NA	NA	NA	NA
AWZ51068.1\|1091962_1093153_-	ribosomal RNA large subunit methyltransferase I	NA	NA	NA	NA
AWZ51069.1\|1093247_1093526_+	acylphosphatase	NA	NA	NA	NA
AWZ51070.1\|1093522_1093852_-	sulfurtransferase TusE	NA	NA	NA	NA
AWZ51071.1\|1093942_1094602_-	BAX inhibitor protein	A0A2H4JFM9	uncultured_Caudovirales_phage	5.2e-48	54.9
AWZ51072.1\|1097407_1098621_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ51073.1\|1098672_1100097_-	exonuclease	NA	NA	NA	NA
AWZ51074.1\|1100189_1100381_-	DUF1482 domain-containing protein	NA	NA	NA	NA
AWZ51075.1\|1100377_1100566_-	cell division inhibition protein DicB	NA	NA	NA	NA
AWZ54992.1\|1101097_1101472_-	hypothetical protein	NA	NA	NA	NA
AWZ51076.1\|1101483_1101636_-	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	3.9e-07	53.2
AWZ51077.1\|1101673_1101868_-	hypothetical protein	NA	NA	NA	NA
AWZ51078.1\|1101908_1102625_-	LexA family transcriptional repressor	H9C160	Pectobacterium_phage	3.8e-52	42.0
AWZ51079.1\|1102674_1102890_+	transcriptional regulator	NA	NA	NA	NA
AWZ51080.1\|1102886_1103312_+	Rha family transcriptional regulator	NA	NA	NA	NA
AWZ51081.1\|1103383_1104454_+	phage replisome organizer	A0A088CD36	Shigella_phage	3.2e-63	65.2
AWZ51082.1\|1104494_1104917_+	DUF977 domain-containing protein	A0A0U2QQN3	Escherichia_phage	1.1e-64	92.1
AWZ51083.1\|1104913_1105210_+	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	7.5e-47	93.7
AWZ51084.1\|1105206_1105668_+	hypothetical protein	Q8VNQ2	Enterobacteria_phage	3.4e-38	92.9
AWZ51085.1\|1105645_1106002_+	hypothetical protein	A0A2R2Z307	Escherichia_phage	3.0e-58	98.3
AWZ51086.1\|1106052_1106265_+	hypothetical protein	A0A2R2Z310	Escherichia_phage	5.8e-33	94.3
AWZ51087.1\|1106350_1106515_+	O-polysaccharide acetyltransferase inhibitor	A0A1I9LJM2	Stx_converting_phage	2.0e-17	90.7
AWZ51088.1\|1106516_1106780_+	hypothetical protein	A0A2P0P958	Salmonella_phage	8.8e-31	72.4
AWZ51089.1\|1106790_1107660_+	DUF551 domain-containing protein	A0A1U9AJ59	Stx1_converting_phage	5.2e-120	76.8
AWZ51090.1\|1107775_1107880_+	hypothetical protein	NA	NA	NA	NA
AWZ51091.1\|1107868_1108024_-	hypothetical protein	Q7Y2Q9	Escherichia_phage	1.9e-09	83.8
AWZ51092.1\|1108068_1108281_+	Hok/Gef family protein	A0A0U2QV81	Escherichia_phage	1.2e-25	91.4
AWZ51093.1\|1108448_1108709_+	hypothetical protein	NA	NA	NA	NA
AWZ51094.1\|1108728_1109778_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	3.4e-110	54.9
AWZ51095.1\|1109790_1110162_+	hypothetical protein	V5URS4	Shigella_phage	1.3e-35	63.7
AWZ51096.1\|1110151_1110523_+	antitermination protein	Q777W5	Enterobacteria_phage	1.0e-53	84.0
AWZ51097.1\|1110674_1111493_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AWZ51098.1\|1111779_1111977_+	TrmB family transcriptional regulator	S5MQK8	Escherichia_phage	2.6e-27	96.9
AWZ51099.1\|1112114_1112828_+	AraC family transcriptional regulator	NA	NA	NA	NA
AWZ51100.1\|1113274_1113478_-	hypothetical protein	Q8VNP0	Enterobacteria_phage	1.8e-28	96.7
AWZ51101.1\|1113595_1115446_+	DUF1737 domain-containing protein	B6DZ89	Enterobacteria_phage	0.0e+00	95.9
AWZ51102.1\|1115724_1115886_-	hypothetical protein	NA	NA	NA	NA
AWZ51103.1\|1115884_1116100_+\|holin	holin	Q6H9V8	Enterobacteria_phage	1.7e-32	97.2
AWZ51104.1\|1116062_1116407_-	hypothetical protein	NA	NA	NA	NA
AWZ51105.1\|1116355_1116592_-	hypothetical protein	NA	NA	NA	NA
AWZ51106.1\|1116560_1116743_+	hypothetical protein	NA	NA	NA	NA
AWZ51107.1\|1116787_1117321_+	lysozyme	A0A1U9AJ98	Stx1_converting_phage	3.1e-99	94.4
AWZ51108.1\|1117541_1117655_+	hypothetical protein	A0A2L1IV24	Escherichia_phage	5.6e-11	97.3
AWZ51109.1\|1117656_1118124_+\|lysis	lysis protein	Q7AYI6	Enterobacteria_phage	2.2e-72	93.5
AWZ51110.1\|1118206_1118347_+	hypothetical protein	NA	NA	NA	NA
AWZ51111.1\|1118588_1118903_+	PerC family transcriptional regulator	NA	NA	NA	NA
AWZ54993.1\|1118984_1119209_-	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	1.7e-19	90.6
AWZ51112.1\|1119258_1120472_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ51113.1\|1120558_1121452_-	molecular chaperone Tir	NA	NA	NA	NA
AWZ51114.1\|1121897_1122281_-	secretion protein EspV	Q6H9S1	Enterobacteria_phage	4.4e-55	84.3

DBSCAN-SWA_5

1345857 : 1414540

Stx2-converting_phage(33.96%)

capsid,lysis,transposase,terminase,holin,head,integrase,tRNA,tail

attL 1340951:1340965|attR 1347432:1347446

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1340951:1340965	attL	NA	NA	NA	NA
AWZ51338.1\|1345857_1346976_-\|integrase	integrase	Q77Z04	Phage_21	2.9e-83	43.9
AWZ51339.1\|1346944_1347214_-	excisionase	NA	NA	NA	NA
AWZ51340.1\|1347275_1349741_-	exonuclease	A0A192Y6E0	Salmonella_phage	8.8e-56	57.1
1347432:1347446	attR	NA	NA	NA	NA
AWZ51341.1\|1349833_1350025_-	DUF1482 domain-containing protein	NA	NA	NA	NA
AWZ51342.1\|1350021_1350210_-	cell division inhibition protein DicB	NA	NA	NA	NA
AWZ51343.1\|1350693_1350912_-	hypothetical protein	NA	NA	NA	NA
AWZ51344.1\|1350952_1351342_-	hypothetical protein	NA	NA	NA	NA
AWZ51345.1\|1351268_1351433_-	hypothetical protein	NA	NA	NA	NA
AWZ51346.1\|1351637_1351916_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
AWZ51347.1\|1351917_1352145_-	hypothetical protein	NA	NA	NA	NA
AWZ51348.1\|1352129_1352564_-	hypothetical protein	NA	NA	NA	NA
AWZ51349.1\|1352598_1352901_+	transcriptional regulator	K7PHA1	Enterobacteria_phage	1.5e-05	34.8
AWZ51350.1\|1352897_1353323_+	Rha family transcriptional regulator	NA	NA	NA	NA
AWZ55012.1\|1353345_1354308_+	DNA-binding protein	U5P0A0	Shigella_phage	2.1e-69	51.2
AWZ51351.1\|1354802_1356016_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ51352.1\|1356530_1357109_+	hypothetical protein	A0A0U2RXY7	Escherichia_phage	2.6e-104	100.0
AWZ51353.1\|1357068_1358166_-	beta family protein	A0A0U2S621	Escherichia_phage	1.4e-210	99.5
AWZ51354.1\|1358800_1360014_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ51355.1\|1360051_1360192_+	type I toxin-antitoxin system hok family toxin	A0A0U2QV81	Escherichia_phage	2.2e-12	95.0
AWZ51356.1\|1360233_1360413_-	hypothetical protein	NA	NA	NA	NA
AWZ51357.1\|1360359_1360632_+	hypothetical protein	I6PCV7	Cronobacter_phage	9.4e-12	49.2
AWZ51358.1\|1360633_1361689_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	2.4e-87	47.8
AWZ51359.1\|1361689_1362055_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.6e-38	64.3
AWZ51360.1\|1362063_1362594_+	DUF1133 domain-containing protein	A0A0U2S606	Escherichia_phage	9.3e-72	72.6
AWZ51361.1\|1362712_1363033_+	lipoprotein	S5MQK8	Escherichia_phage	2.5e-35	97.4
AWZ51362.1\|1363183_1364242_+	site-specific DNA-methyltransferase	S5MDR0	Escherichia_phage	2.0e-198	94.0
AWZ51363.1\|1364733_1364919_+	hypothetical protein	Q5MBW5	Stx1-converting_phage	4.6e-26	94.6
AWZ51364.1\|1365038_1366889_+	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	0.0e+00	98.1
AWZ51365.1\|1367167_1367329_-	hypothetical protein	NA	NA	NA	NA
AWZ51366.1\|1367327_1367543_+\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	7.7e-33	98.6
AWZ51367.1\|1367547_1367892_+	DUF1327 domain-containing protein	A0A0P0ZD64	Stx2-converting_phage	1.0e-58	100.0
AWZ51368.1\|1367942_1368476_+	lysozyme	A0A0N7KZF9	Stx2-converting_phage	7.4e-101	98.9
AWZ51369.1\|1368746_1369316_+	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
AWZ51370.1\|1369469_1369937_+\|lysis	lysis protein	Q6H9V3	Enterobacteria_phage	6.9e-79	100.0
AWZ51371.1\|1370299_1370527_-	DUF3950 domain-containing protein	A0A0P0ZE23	Stx2-converting_phage	1.7e-35	100.0
AWZ51372.1\|1370568_1370934_+	HNH endonuclease	B6ETE5	Enterobacteria_phage	2.0e-65	99.2
AWZ51373.1\|1370902_1371109_+	hypothetical protein	H6WZK7	Escherichia_phage	7.4e-25	83.8
AWZ51374.1\|1371224_1371788_+\|terminase	terminase small subunit	A0A0P0ZDD1	Stx2-converting_phage	3.8e-79	100.0
AWZ51375.1\|1371784_1373446_+\|terminase	terminase large subunit	H6WZK9	Escherichia_phage	0.0e+00	98.9
AWZ51376.1\|1373509_1375447_+\|capsid	phage major capsid protein	B6ETE8	Enterobacteria_phage	0.0e+00	99.7
AWZ55013.1\|1375491_1375713_+	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
AWZ51377.1\|1378401_1378728_+\|head,tail	phage gp6-like head-tail connector protein	B6ETF0	Enterobacteria_phage	7.0e-54	100.0
AWZ51378.1\|1378737_1379088_+\|head,tail	head-tail adaptor protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
AWZ51379.1\|1379084_1379531_+	hypothetical protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
AWZ51380.1\|1379527_1379872_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
AWZ51381.1\|1379938_1380655_+\|tail	phage tail protein	A0A0P0ZD29	Stx2-converting_phage	5.6e-128	98.7
AWZ51382.1\|1380660_1381035_+\|tail	phage tail protein	A0A0P0ZE84	Stx2-converting_phage	6.6e-64	98.4
AWZ51383.1\|1381058_1381340_+\|tail	phage tail protein	A0A0P0ZDE6	Stx2-converting_phage	1.3e-45	100.0
AWZ51384.1\|1381391_1384634_+\|tail	phage tail tape measure protein	A0A0P0ZE78	Stx2-converting_phage	0.0e+00	98.5
AWZ51385.1\|1384626_1384968_+\|tail	phage tail protein	H6WZM2	Escherichia_phage	5.3e-60	95.6
AWZ51386.1\|1384967_1385666_+\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	4.4e-130	97.4
AWZ55014.1\|1385682_1386003_-	Arc family DNA-binding protein	A0A0P0ZBD1	Stx2-converting_phage	3.0e-49	100.0
AWZ51387.1\|1386110_1386284_+	Arc family DNA-binding protein	A0A0P0ZC65	Stx2-converting_phage	3.4e-23	100.0
AWZ51388.1\|1387331_1388069_+\|tail	phage tail protein	A0A0P0ZDT1	Stx2-converting_phage	1.9e-147	98.8
AWZ51389.1\|1387966_1388647_+\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	8.7e-115	98.2
AWZ51390.1\|1388883_1392363_+	host specificity protein J	A0A0P0ZDT4	Stx2-converting_phage	0.0e+00	97.4
AWZ51391.1\|1392429_1393029_+	Ail/Lom family protein	Q687E7	Enterobacteria_phage	8.0e-112	100.0
AWZ51392.1\|1393093_1394416_+\|tail	phage tail protein	Q687E6	Enterobacteria_phage	2.4e-76	99.1
AWZ51393.1\|1394417_1394687_+\|tail	phage tail protein	A0A2R2Z347	Escherichia_phage	2.4e-44	98.9
AWZ51394.1\|1394902_1397251_+	type III secretion system effector HECT-type E3 ubiquitin transferase	NA	NA	NA	NA
AWZ51395.1\|1397841_1401243_+	DUF4765 domain-containing protein	A0A0N7KZG3	Stx2-converting_phage	1.0e-219	39.2
AWZ51396.1\|1401399_1401990_+	hypothetical protein	NA	NA	NA	NA
AWZ51397.1\|1402012_1402138_+	NleB	Q8HAB2	Salmonella_phage	8.7e-05	58.3
AWZ51398.1\|1402217_1402493_-	secretion protein EspO	NA	NA	NA	NA
AWZ51399.1\|1402553_1403915_-	type III secretion protein GogB	Q9MBM1	Phage_Gifsy-1	4.0e-50	28.9
AWZ51400.1\|1404035_1404248_-	hypothetical protein	NA	NA	NA	NA
AWZ51401.1\|1404278_1405142_-	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	6.7e-11	28.7
AWZ51402.1\|1405125_1406262_-	Fe3+/spermidine/putrescine ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	9.4e-29	39.8
AWZ55015.1\|1406240_1406456_-	hypothetical protein	NA	NA	NA	NA
AWZ51403.1\|1406511_1407741_+	peptidase T	NA	NA	NA	NA
AWZ51404.1\|1407886_1409008_-	50S ribosomal protein L16 arginine hydroxylase	NA	NA	NA	NA
AWZ51405.1\|1409083_1410544_-	sensor protein PhoQ	NA	NA	NA	NA
AWZ51406.1\|1410543_1411215_-	two-component system response regulator PhoP	NA	NA	NA	NA
AWZ51407.1\|1411382_1412753_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.2e-108	44.9
AWZ55016.1\|1412756_1413398_-	lysogenization protein HflD	NA	NA	NA	NA
AWZ51408.1\|1413433_1414540_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA

DBSCAN-SWA_6

1515756 : 1588778

Enterobacteria_phage(45.1%)

lysis,transposase,terminase,holin,protease,portal,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ51502.1\|1515756_1516305_+	recombinase family protein	G8I4U3	Mycobacterium_phage	2.7e-21	36.1
AWZ51503.1\|1517815_1518004_-	hypothetical protein	NA	NA	NA	NA
AWZ51504.1\|1518151_1519364_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ51505.1\|1519428_1519965_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	4.1e-59	71.9
AWZ55026.1\|1519997_1520279_+	DNA-binding protein	A0A222YXX1	Escherichia_phage	1.6e-30	75.8
AWZ51506.1\|1520275_1520572_+	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	4.4e-47	93.7
AWZ51507.1\|1520568_1521030_+	hypothetical protein	Q8VNQ2	Enterobacteria_phage	6.9e-39	95.2
AWZ51508.1\|1521007_1521364_+	hypothetical protein	A0A2R2Z307	Escherichia_phage	6.7e-58	97.5
AWZ51509.1\|1521459_1521831_+	hypothetical protein	A0A0N7KZJ2	Stx2-converting_phage	2.7e-49	78.9
AWZ51510.1\|1521827_1522181_+	DUF551 domain-containing protein	Q9EY98	Enterobacteria_phage	5.5e-36	65.0
AWZ51511.1\|1522386_1522686_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A2R2Z2Y1	Escherichia_phage	1.6e-49	96.0
AWZ51512.1\|1522691_1522949_-	type II toxin-antitoxin system ParD family antitoxin	A0A0N7C055	Escherichia_phage	6.6e-31	88.0
AWZ51513.1\|1523084_1523363_+	hypothetical protein	I6PCV7	Cronobacter_phage	6.9e-10	46.9
AWZ51514.1\|1523364_1524414_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.0e-109	54.3
AWZ51515.1\|1524426_1524801_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	2.4e-34	62.7
AWZ51516.1\|1524797_1525619_+	antitermination protein	K7P7B9	Enterobacteria_phage	2.8e-83	61.9
AWZ51517.1\|1525845_1526043_+	TrmB family transcriptional regulator	S5MQK8	Escherichia_phage	1.8e-28	98.5
AWZ51518.1\|1526193_1527252_+	site-specific DNA-methyltransferase	S5MDR0	Escherichia_phage	1.7e-205	98.0
AWZ51519.1\|1527846_1529793_+	DUF1737 domain-containing protein	Q9EYC8	Enterobacteria_phage	0.0e+00	99.1
AWZ51520.1\|1529930_1530110_+	DUF1378 domain-containing protein	A0A2R2Z345	Escherichia_phage	2.2e-25	100.0
AWZ51521.1\|1530150_1530396_+	DUF826 domain-containing protein	A0A088CE63	Shigella_phage	3.2e-19	98.8
AWZ51522.1\|1530473_1530689_+\|holin	holin	A0A2R2Z340	Escherichia_phage	1.2e-33	100.0
AWZ51523.1\|1530963_1532176_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ51524.1\|1532599_1533133_+	lysozyme	B6DZ92	Enterobacteria_phage	2.1e-100	97.2
AWZ51525.1\|1533431_1533899_+\|lysis	lysis protein	Q7AYI6	Enterobacteria_phage	3.9e-74	96.1
AWZ51526.1\|1534312_1534789_+	DUF1441 domain-containing protein	Q8VNN8	Enterobacteria_phage	3.3e-84	100.0
AWZ51527.1\|1534785_1536909_+\|terminase	phage terminase large subunit family protein	Q9EYD1	Enterobacteria_phage	0.0e+00	100.0
AWZ51528.1\|1536881_1537118_+	hypothetical protein	Q687G1	Enterobacteria_phage	4.5e-34	100.0
AWZ51529.1\|1537117_1538620_+\|portal	phage portal protein	Q9EYD2	Enterobacteria_phage	4.8e-291	100.0
AWZ55027.1\|1538633_1540589_+	peptidase S14	S5M7Q8	Escherichia_phage	0.0e+00	99.8
AWZ51530.1\|1540676_1541003_+	DUF2190 domain-containing protein	Q9EYD5	Enterobacteria_phage	6.1e-50	100.0
AWZ51531.1\|1540995_1541277_+	DNA breaking-rejoining protein	Q8VNN4	Enterobacteria_phage	3.9e-45	97.8
AWZ51532.1\|1541279_1541903_+\|tail	phage tail protein	Q9EYD6	Enterobacteria_phage	6.6e-101	100.0
AWZ51533.1\|1541915_1542314_+\|tail	phage tail protein	Q9EYD7	Enterobacteria_phage	5.9e-71	100.0
AWZ51534.1\|1542321_1543074_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	5.8e-136	100.0
AWZ51535.1\|1543087_1543510_+\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	5.1e-73	100.0
AWZ51536.1\|1543536_1543845_+\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	1.3e-54	100.0
AWZ51537.1\|1543888_1546534_+\|tail	phage tail tape measure protein	Q9EYE1	Enterobacteria_phage	0.0e+00	99.4
AWZ51538.1\|1546530_1546860_+\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
AWZ51539.1\|1547567_1548311_+\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	1.5e-147	98.4
AWZ51540.1\|1548208_1548889_+\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	8.7e-115	98.2
AWZ51541.1\|1549125_1552602_+	DUF1983 domain-containing protein	Q687E8	Enterobacteria_phage	0.0e+00	96.6
AWZ51542.1\|1552669_1553269_+	Ail/Lom family protein	Q687E7	Enterobacteria_phage	8.8e-111	99.0
AWZ51543.1\|1553333_1554647_+\|tail	phage tail protein	A0A0P0ZCC1	Stx2-converting_phage	3.7e-77	97.0
AWZ51544.1\|1554648_1554918_+\|tail	phage tail protein	A0A1U9AJC2	Stx1_converting_phage	2.7e-43	97.8
AWZ51545.1\|1556053_1556644_+	protein kinase	NA	NA	NA	NA
AWZ51546.1\|1557680_1558187_-	ferritin-like domain-containing protein	NA	NA	NA	NA
AWZ51547.1\|1558232_1558733_-	YciE/YciF family protein	NA	NA	NA	NA
AWZ51548.1\|1558818_1558998_-	hypothetical protein	NA	NA	NA	NA
AWZ51549.1\|1559378_1560185_-	tryptophan synthase subunit alpha	NA	NA	NA	NA
AWZ51550.1\|1560184_1561378_-	tryptophan synthase subunit beta	NA	NA	NA	NA
AWZ55028.1\|1561389_1562748_-	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase	A0A0P0IR83	Acinetobacter_phage	8.6e-37	40.7
AWZ51551.1\|1562751_1564347_-	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	3.8e-52	38.5
AWZ51552.1\|1564346_1565909_-	anthranilate synthase component I	NA	NA	NA	NA
AWZ55029.1\|1566000_1566045_-	trp operon leader peptide	NA	NA	NA	NA
AWZ51553.1\|1566182_1567064_+	phosphatase	NA	NA	NA	NA
AWZ51554.1\|1567060_1567681_+	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
AWZ51555.1\|1567781_1568654_+	23S rRNA pseudouridylate synthase B	NA	NA	NA	NA
AWZ51556.1\|1568693_1569284_-	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
AWZ51557.1\|1569280_1570039_-	NAD(P)-dependent oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	4.4e-06	24.5
AWZ51558.1\|1570258_1571308_+\|protease	protease	A0A2H4UUF9	Bodo_saltans_virus	1.3e-21	31.5
AWZ51559.1\|1571343_1571595_-	hypothetical protein	NA	NA	NA	NA
AWZ51560.1\|1571639_1571852_+	hypothetical protein	NA	NA	NA	NA
AWZ51561.1\|1571974_1574572_+	DNA topoisomerase 1	A0A2K9L1Q2	Tupanvirus	1.7e-86	34.7
AWZ51562.1\|1574781_1575756_+	LysR family transcriptional regulator CysB	NA	NA	NA	NA
AWZ51563.1\|1576050_1576215_+	YmiA family putative membrane protein	NA	NA	NA	NA
AWZ51564.1\|1576217_1576385_+	hypothetical protein	NA	NA	NA	NA
AWZ51565.1\|1576521_1576704_+	acnA regulatory region 60-length spurious protein	NA	NA	NA	NA
AWZ51566.1\|1576757_1579433_+	aconitate hydratase AcnA	NA	NA	NA	NA
AWZ51567.1\|1579496_1580087_-	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	7.7e-43	48.9
AWZ51568.1\|1580256_1581021_+	phosphatidylglycerophosphatase B	NA	NA	NA	NA
AWZ51569.1\|1581169_1581478_+	LPS assembly protein A	NA	NA	NA	NA
AWZ51570.1\|1581484_1582654_+	LPS assembly protein B	NA	NA	NA	NA
AWZ51571.1\|1582845_1583583_+	orotidine-5'-phosphate decarboxylase	NA	NA	NA	NA
AWZ51572.1\|1583582_1583909_+	stress response translation initiation inhibitor YciH	NA	NA	NA	NA
AWZ51573.1\|1584034_1584253_-	osmotically-inducible lipoprotein B	NA	NA	NA	NA
AWZ51574.1\|1584521_1585271_-	DeoR family transcriptional regulator	NA	NA	NA	NA
AWZ51575.1\|1585360_1585534_-	hypothetical protein	NA	NA	NA	NA
AWZ51576.1\|1587564_1588778_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7

DBSCAN-SWA_7

1649162 : 1744923

121

Escherichia_phage(40.45%)

capsid,lysis,transposase,holin,terminase,head,integrase,tRNA,tail

attL 1707871:1707930|attR 1738616:1739927

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ55031.1\|1649162_1650395_-	sensor domain-containing diguanylate cyclase	A0A127AWB9	Bacillus_phage	3.1e-17	39.5
AWZ51635.1\|1650649_1651633_+	zinc transporter ZntB	NA	NA	NA	NA
AWZ51636.1\|1651907_1652081_+	hypothetical protein	NA	NA	NA	NA
AWZ51637.1\|1652110_1653484_+	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	6.6e-53	33.1
AWZ51638.1\|1653612_1654548_-\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	5.9e-146	98.8
AWZ51639.1\|1654599_1655835_-\|integrase	site-specific integrase	A0A0U2JGI6	Escherichia_phage	3.8e-241	99.5
AWZ51640.1\|1655836_1656052_-	hypothetical protein	A0A0U2RY08	Escherichia_phage	1.8e-37	100.0
AWZ55033.1\|1656151_1656340_-	DUF1187 domain-containing protein	A0A0U2QL97	Escherichia_phage	5.5e-27	98.4
AWZ55032.1\|1656377_1656527_-	restriction alleviation protein, Lar family	A0A0U2QQP4	Escherichia_phage	2.5e-22	95.9
AWZ51641.1\|1656582_1657392_-	recombination protein RecT	A0A1P8DTF2	Proteus_phage	4.0e-106	71.5
AWZ51642.1\|1657384_1659985_-	exodeoxyribonuclease VIII	A0A0U2I1R6	Escherichia_phage	6.1e-249	63.5
AWZ51643.1\|1660086_1660362_-	hypothetical protein	A0A0U2QW85	Escherichia_phage	4.0e-42	95.6
AWZ55034.1\|1660436_1660607_-	hypothetical protein	A0A0U2SHB5	Escherichia_phage	3.6e-17	71.4
AWZ51644.1\|1660606_1660828_-	cell division protein FtsZ	A0A0U2RTC4	Escherichia_phage	2.0e-36	98.6
AWZ51645.1\|1660956_1661235_+	hypothetical protein	NA	NA	NA	NA
AWZ51646.1\|1661269_1661758_+	superinfection exclusion protein B	NA	NA	NA	NA
AWZ51647.1\|1661754_1661910_-	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	6.1e-08	55.3
AWZ51648.1\|1661920_1662100_-	hypothetical protein	NA	NA	NA	NA
AWZ51649.1\|1662087_1662306_-	hypothetical protein	NA	NA	NA	NA
AWZ51650.1\|1662342_1662762_-	transcriptional regulator	A0A2I6PIE7	Escherichia_phage	5.5e-19	46.5
AWZ51651.1\|1662841_1663096_+	hypothetical protein	A0A2I6PIE5	Escherichia_phage	1.3e-18	61.6
AWZ51652.1\|1663092_1663515_+	hypothetical protein	A0A0U2RXZ9	Escherichia_phage	1.3e-68	92.9
AWZ51653.1\|1663592_1664381_+	hypothetical protein	G9L6A8	Escherichia_phage	2.0e-41	64.3
AWZ51654.1\|1664387_1665134_+	replication protein	V5UQI5	Shigella_phage	5.6e-115	81.3
AWZ51655.1\|1665105_1665918_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	7.5e-121	90.5
AWZ51656.1\|1665933_1666356_+	DUF977 domain-containing protein	A0A0U2QQN3	Escherichia_phage	3.1e-62	88.5
AWZ51657.1\|1666461_1666674_+	hypothetical protein	A0A2R2Z310	Escherichia_phage	5.8e-33	94.3
AWZ51658.1\|1666759_1666924_+	O-polysaccharide acetyltransferase inhibitor	A0A1I9LJM2	Stx_converting_phage	2.0e-17	90.7
AWZ51659.1\|1666925_1667189_+	hypothetical protein	A0A2P0P958	Salmonella_phage	8.8e-31	72.4
AWZ51660.1\|1667199_1667361_+	hypothetical protein	A0A192Y6F5	Salmonella_phage	3.2e-15	89.4
AWZ51661.1\|1667439_1667685_+	hypothetical protein	Q9G078	Enterobacteria_phage	5.9e-13	70.7
AWZ51662.1\|1668116_1669268_+	DNA cytosine methyltransferase	Q8JKX6	Natrialba_phage	1.0e-22	36.9
AWZ51663.1\|1669235_1670225_-	hypothetical protein	NA	NA	NA	NA
AWZ51664.1\|1670224_1671616_-	ATPase	NA	NA	NA	NA
AWZ51665.1\|1672115_1672715_+	DUF1367 domain-containing protein	A0A0U2RT94	Escherichia_phage	1.1e-105	92.0
AWZ51666.1\|1672714_1673005_+	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	3.3e-47	87.5
AWZ51667.1\|1673001_1673556_+	antiterminator	A0A0U2S606	Escherichia_phage	5.0e-68	69.1
AWZ51668.1\|1674117_1674549_+	tellurite resistance protein	H6WZJ6	Escherichia_phage	3.3e-67	97.2
AWZ51669.1\|1675119_1676973_+	DUF1737 domain-containing protein	B6DZ89	Enterobacteria_phage	0.0e+00	96.3
AWZ51670.1\|1677122_1677338_+\|holin	holin	Q6H9V8	Enterobacteria_phage	1.3e-32	97.2
AWZ51671.1\|1677342_1677687_+	DUF1327 domain-containing protein	A0A0P0ZD64	Stx2-converting_phage	1.8e-55	95.6
AWZ51672.1\|1677737_1678271_+	lysozyme	B6DZ92	Enterobacteria_phage	1.3e-100	97.7
AWZ51673.1\|1678544_1679084_+	ant domain protein	Q5MBW0	Stx1-converting_phage	3.0e-86	99.4
AWZ51674.1\|1679086_1680300_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ51675.1\|1680376_1680553_+	phage antirepressor protein	Q5MBW0	Stx1-converting_phage	3.3e-26	98.3
AWZ55035.1\|1680781_1681249_+\|lysis	lysis protein	Q7AYI6	Enterobacteria_phage	2.2e-72	93.5
AWZ55036.1\|1681278_1681479_+	hypothetical protein	Q9T1L1	Enterobacteria_phage	7.2e-09	71.8
AWZ51676.1\|1681400_1681652_+	hypothetical protein	H6WZK4	Escherichia_phage	3.2e-30	95.7
AWZ51677.1\|1681587_1681914_+	hypothetical protein	H6WZK5	Escherichia_phage	6.3e-55	98.1
AWZ51678.1\|1682045_1682246_-	DUF3950 domain-containing protein	H6WZK6	Escherichia_phage	1.3e-29	97.0
AWZ51679.1\|1682287_1682653_+	HNH endonuclease	B6ETE5	Enterobacteria_phage	1.6e-62	96.7
AWZ51680.1\|1682941_1683505_+\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.1e-89	100.0
AWZ51681.1\|1683501_1685163_+\|terminase	terminase large subunit	A0A0N7KZG0	Stx2-converting_phage	0.0e+00	99.3
AWZ51682.1\|1685226_1687164_+\|capsid	phage major capsid protein	H6WZL0	Escherichia_phage	0.0e+00	99.7
AWZ55037.1\|1687208_1687430_+	hypothetical protein	A0A0P0ZD92	Stx2-converting_phage	5.8e-36	100.0
AWZ51683.1\|1689794_1690121_+\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDE0	Stx2-converting_phage	5.4e-54	100.0
AWZ51684.1\|1690130_1690481_+\|head,tail	head-tail adaptor protein	H6WZL5	Escherichia_phage	2.0e-59	100.0
AWZ51685.1\|1690477_1690924_+	hypothetical protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
AWZ51686.1\|1690920_1691265_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	9.4e-57	99.1
AWZ51687.1\|1691333_1692050_+\|tail	phage tail protein	A0A0P0ZD29	Stx2-converting_phage	1.4e-126	97.9
AWZ51688.1\|1692055_1692430_+\|tail	phage tail protein	A0A0N7KZA2	Stx2-converting_phage	3.0e-64	99.2
AWZ51689.1\|1692453_1692735_+\|tail	phage tail protein	A0A0P0ZDE6	Stx2-converting_phage	1.3e-45	100.0
AWZ51690.1\|1692786_1696029_+\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	99.0
AWZ51691.1\|1696021_1696363_+\|tail	phage tail protein	A0A0P0ZCS8	Stx2-converting_phage	8.7e-63	100.0
AWZ51692.1\|1696362_1697061_+\|tail	phage minor tail protein L	H6WZM3	Escherichia_phage	1.3e-129	97.4
AWZ51693.1\|1697071_1697815_+\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	5.4e-150	99.2
AWZ51694.1\|1697712_1698393_+\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	5.7e-106	91.1
AWZ51695.1\|1698346_1698553_+	hypothetical protein	NA	NA	NA	NA
AWZ51696.1\|1698583_1699111_-	superoxide dismutase	Q9MC02	Salmonella_phage	1.8e-59	60.5
AWZ51697.1\|1699244_1702718_+\|tail	phage tail protein	A0A0P0ZBW1	Stx2-converting_phage	0.0e+00	89.9
AWZ51698.1\|1702785_1703385_+	Ail/Lom family protein	Q9EV15	Enterobacteria_phage	4.1e-108	97.0
AWZ51699.1\|1703536_1704841_+\|tail	phage tail protein	A0A0P0ZCC1	Stx2-converting_phage	1.2e-72	95.4
AWZ51700.1\|1704842_1705112_+\|tail	phage tail protein	A0A1U9AJC2	Stx1_converting_phage	2.7e-43	97.8
AWZ55038.1\|1706226_1706349_+	hypothetical protein	Q687E5	Enterobacteria_phage	3.8e-05	91.3
AWZ51701.1\|1706455_1707367_+	T3SS effector protein NleH	A5LH48	Enterobacteria_phage	3.0e-134	82.2
1707871:1707930	attL	NA	NA	NA	NA
AWZ51702.1\|1707913_1709127_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ51703.1\|1710153_1710432_-	secretion protein EspO	NA	NA	NA	NA
AWZ51704.1\|1710820_1711006_+	hypothetical protein	NA	NA	NA	NA
AWZ51705.1\|1711142_1711790_-	DUF1076 domain-containing protein	B6ETE1	Enterobacteria_phage	1.6e-41	41.1
AWZ51706.1\|1711973_1712564_+	bfpT-regulated chaperone	NA	NA	NA	NA
AWZ55039.1\|1714292_1714721_+	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	1.4e-22	42.1
AWZ51707.1\|1715069_1715423_-	hypothetical protein	NA	NA	NA	NA
AWZ55040.1\|1715513_1716233_+	TonB system transport protein TonB	NA	NA	NA	NA
AWZ51708.1\|1716272_1716671_-	acyl-CoA thioester hydrolase YciA	NA	NA	NA	NA
AWZ51709.1\|1716775_1717315_-	intracellular septation protein A	NA	NA	NA	NA
AWZ51710.1\|1717344_1718088_-	UPF0259 family protein	NA	NA	NA	NA
AWZ51711.1\|1718444_1719083_+	outer membrane protein OmpW	NA	NA	NA	NA
AWZ51712.1\|1719128_1720259_-\|integrase	integrase	O21940	Phage_21	3.4e-103	51.4
AWZ51713.1\|1720236_1720485_-	excisionase	NA	NA	NA	NA
AWZ51714.1\|1720549_1723021_-	exonuclease	A0A192Y6E0	Salmonella_phage	5.5e-58	57.7
AWZ51715.1\|1723116_1723305_-	DUF1482 domain-containing protein	NA	NA	NA	NA
AWZ51716.1\|1723301_1723490_-	cell division inhibitor	NA	NA	NA	NA
AWZ51717.1\|1723760_1724057_+	hypothetical protein	NA	NA	NA	NA
AWZ51718.1\|1724050_1724284_+	hypothetical protein	NA	NA	NA	NA
AWZ51719.1\|1724261_1724669_-	hypothetical protein	A0A2R2Z306	Escherichia_phage	7.0e-11	37.8
AWZ51720.1\|1724691_1724910_-	hypothetical protein	NA	NA	NA	NA
AWZ51721.1\|1724982_1725282_-	hypothetical protein	NA	NA	NA	NA
AWZ51722.1\|1725546_1725954_-	transcriptional regulator	I6PD69	Cronobacter_phage	9.8e-29	49.6
AWZ51723.1\|1726098_1726257_+	transcriptional regulator	NA	NA	NA	NA
AWZ51724.1\|1726240_1726792_+	hypothetical protein	NA	NA	NA	NA
AWZ51725.1\|1727592_1728258_+	replication protein	A0A0U2JGJ0	Escherichia_phage	1.9e-85	98.7
AWZ51726.1\|1728291_1729026_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	2.9e-108	84.3
AWZ51727.1\|1729885_1730644_+	accessory colonization factor AcfC	NA	NA	NA	NA
AWZ51728.1\|1730922_1731135_+	Hok/Gef family protein	A0A0U2QV81	Escherichia_phage	1.3e-16	72.9
AWZ51729.1\|1731355_1731613_+	hypothetical protein	NA	NA	NA	NA
AWZ51730.1\|1731682_1731961_+	hypothetical protein	I6PCV7	Cronobacter_phage	2.8e-11	48.4
AWZ51731.1\|1731962_1733018_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	2.9e-88	47.6
AWZ51732.1\|1733018_1733384_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.6e-38	67.5
AWZ51733.1\|1733380_1734070_+	antiterminator	I6PDF8	Cronobacter_phage	4.0e-59	51.1
AWZ51734.1\|1734100_1734247_+	antiterminator	NA	NA	NA	NA
AWZ51735.1\|1735420_1735549_+	hypothetical protein	NA	NA	NA	NA
AWZ51736.1\|1735597_1737367_+	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	0.0e+00	96.8
AWZ51737.1\|1737418_1738631_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ51738.1\|1738597_1738720_+	AMP nucleosidase	A0A0N7BTS3	Escherichia_phage	4.3e-09	86.1
AWZ51739.1\|1738721_1738991_+\|tail	phage tail protein	Q687E5	Enterobacteria_phage	6.4e-45	100.0
AWZ51740.1\|1739131_1740007_+	secretion protein EspS	A0A0P0ZCT1	Stx2-converting_phage	1.5e-162	100.0
1738616:1739927	attR	NA	NA	NA	NA
AWZ55041.1\|1740231_1740603_-	DUF1076 domain-containing protein	A0A0P0ZBX1	Stx2-converting_phage	1.7e-67	99.2
AWZ55042.1\|1741477_1741792_-	DinI family protein	Q687E4	Enterobacteria_phage	1.3e-25	81.9
AWZ51741.1\|1741851_1743135_+	MFS transporter	NA	NA	NA	NA
AWZ51742.1\|1743223_1744684_+	mannitol dehydrogenase family protein	G8DCZ3	Micromonas_pusilla_virus	5.6e-42	30.3
AWZ51743.1\|1744719_1744923_-	protein YdfZ	J9Q802	Salmonella_phage	1.6e-11	55.2

DBSCAN-SWA_8

1943032 : 1995797

Stx2-converting_phage(45.65%)

capsid,lysis,transposase,terminase,holin,portal,head,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ51905.1\|1943032_1944166_+	porin OmpS2	Q1MVN1	Enterobacteria_phage	1.2e-116	58.3
AWZ51906.1\|1944306_1944741_+	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	1.4e-28	52.8
AWZ51907.1\|1945321_1945963_-	DUF1076 domain-containing protein	B6DZC0	Enterobacteria_phage	6.8e-109	100.0
AWZ51908.1\|1946044_1946674_-	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	1.3e-77	92.2
AWZ51909.1\|1946746_1947322_-	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	5.3e-89	88.4
AWZ51910.1\|1947434_1947704_-\|tail	phage tail protein	A0A0P0ZCV7	Stx2-converting_phage	4.2e-44	95.5
AWZ51911.1\|1947705_1949019_-\|tail	phage tail protein	A0A0P0ZCC1	Stx2-converting_phage	7.9e-80	97.9
AWZ51912.1\|1949083_1949683_-	outer membrane protein	B6ETG5	Enterobacteria_phage	3.0e-111	100.0
AWZ51913.1\|1949753_1953251_-\|tail	phage tail protein	A0A0P0ZEQ8	Stx2-converting_phage	0.0e+00	94.8
AWZ51914.1\|1953593_1954274_-\|tail	tail assembly protein	A0A0P0ZC16	Stx2-converting_phage	1.0e-110	97.8
AWZ51915.1\|1954171_1954915_-\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	1.1e-147	97.2
AWZ51916.1\|1954920_1955619_-\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	7.6e-130	97.0
AWZ51917.1\|1955618_1955960_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	4.7e-61	97.3
AWZ51918.1\|1955952_1957395_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	5.1e-229	93.3
AWZ51919.1\|1957413_1957779_+\|transposase	transposase	NA	NA	NA	NA
AWZ51920.1\|1957778_1958966_+\|transposase	IS91 family transposase	NA	NA	NA	NA
AWZ51921.1\|1959145_1961023_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	5.9e-278	91.5
AWZ51922.1\|1961074_1961356_-	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	3.9e-45	98.9
AWZ51923.1\|1961379_1961754_-\|tail	phage tail protein	A0A0P0ZE84	Stx2-converting_phage	5.0e-64	98.4
AWZ51924.1\|1961759_1962476_-\|tail	phage tail protein	A0A0P0ZD29	Stx2-converting_phage	1.2e-125	96.6
AWZ51925.1\|1962542_1962887_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	9.4e-57	99.1
AWZ51926.1\|1962883_1963330_-	hypothetical protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
AWZ51927.1\|1963326_1963677_-\|head,tail	head-tail adaptor protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
AWZ51928.1\|1963686_1964013_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZBH1	Stx2-converting_phage	9.2e-54	100.0
AWZ51929.1\|1964015_1966595_-\|portal	phage portal protein	A0A0P0ZDD0	Stx2-converting_phage	0.0e+00	99.8
AWZ51930.1\|1966540_1966762_-	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
AWZ51931.1\|1966806_1968744_-\|capsid	phage major capsid protein	H6WZL0	Escherichia_phage	0.0e+00	99.7
AWZ51932.1\|1968807_1970469_-\|terminase	terminase large subunit	H6WZK9	Escherichia_phage	0.0e+00	98.9
AWZ51933.1\|1970465_1971029_-\|terminase	terminase small subunit	A0A0P0ZDD1	Stx2-converting_phage	3.8e-79	100.0
AWZ51934.1\|1971212_1971356_-	DNase	NA	NA	NA	NA
AWZ51935.1\|1971318_1971684_-	HNH endonuclease	B6DZ96	Enterobacteria_phage	2.9e-64	96.7
AWZ51936.1\|1971725_1971953_+	DUF3950 domain-containing protein	A0A0P0ZE23	Stx2-converting_phage	1.7e-35	100.0
AWZ51937.1\|1972321_1972546_-	hypothetical protein	NA	NA	NA	NA
AWZ51938.1\|1972542_1973037_-\|lysis	lysis protein	Q9ZXB6	Enterobacteria_phage	4.0e-77	93.8
AWZ51939.1\|1973038_1973257_-	hypothetical protein	Q687G2	Enterobacteria_phage	3.0e-16	91.1
AWZ51940.1\|1973334_1973868_-	lysozyme	A0A0N7KZF9	Stx2-converting_phage	2.8e-100	98.3
AWZ51941.1\|1973918_1974263_-	DUF1327 domain-containing protein	A0A0P0ZD64	Stx2-converting_phage	1.0e-58	100.0
AWZ51942.1\|1974267_1974483_-\|holin	holin	Q6H9V8	Enterobacteria_phage	1.7e-32	97.2
AWZ51943.1\|1974919_1976770_-	DUF1737 domain-containing protein	B6DZ89	Enterobacteria_phage	0.0e+00	98.4
AWZ51944.1\|1977608_1978821_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ51945.1\|1979505_1980027_-	hypothetical protein	NA	NA	NA	NA
AWZ51946.1\|1980010_1980238_-	transcriptional regulator	NA	NA	NA	NA
AWZ51947.1\|1980315_1980723_+	transcriptional regulator	I6PD69	Cronobacter_phage	2.5e-24	46.2
AWZ51948.1\|1980915_1981068_+	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	6.6e-07	53.2
AWZ55051.1\|1981079_1981445_+	hypothetical protein	NA	NA	NA	NA
AWZ51949.1\|1981413_1981701_-	hypothetical protein	NA	NA	NA	NA
AWZ51950.1\|1982116_1982305_+	division inhibition protein DicB	NA	NA	NA	NA
AWZ51951.1\|1982301_1982493_+	DUF1482 domain-containing protein	NA	NA	NA	NA
AWZ51952.1\|1982586_1983030_+	exonuclease VIII	NA	NA	NA	NA
AWZ51953.1\|1983069_1984283_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ51954.1\|1984346_1986371_+	exonuclease	A0A192Y6E0	Salmonella_phage	2.7e-58	56.1
AWZ51955.1\|1986443_1986695_+	DNA-binding protein	S4TND0	Salmonella_phage	2.2e-15	50.0
AWZ51956.1\|1986714_1988010_+	DUF3596 domain-containing protein	B6DZ48	Enterobacteria_phage	1.9e-155	62.1
AWZ51957.1\|1988029_1988140_-	transporter	NA	NA	NA	NA
AWZ51958.1\|1988197_1989217_-	starvation-sensing protein RspB	E3SJ82	Synechococcus_phage	9.7e-17	25.9
AWZ51959.1\|1989228_1990443_-	starvation-sensing protein RspA	Q6A202	Oenococcus_phage	1.4e-46	29.0
AWZ51960.1\|1990423_1990612_-	hypothetical protein	NA	NA	NA	NA
AWZ51961.1\|1990648_1990975_-	YnfA family protein	A0A218MNG8	uncultured_virus	9.9e-24	55.6
AWZ51962.1\|1991109_1991451_+	DUF1283 domain-containing protein	NA	NA	NA	NA
AWZ51963.1\|1991485_1992046_+	spermidine N1-acetyltransferase	NA	NA	NA	NA
AWZ55052.1\|1992048_1992759_-	YnfC family lipoprotein	NA	NA	NA	NA
AWZ51964.1\|1992866_1993172_+	DUF1161 domain-containing protein	NA	NA	NA	NA
AWZ51965.1\|1993370_1995797_+	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	2.0e-214	49.0

DBSCAN-SWA_9

2131564 : 2169648

Enterobacteria_phage(86.11%)

capsid,transposase,terminase,holin,portal,plate,tRNA,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ55059.1\|2131564_2131843_+	DUF4761 domain-containing protein	A0A0A7NV42	Enterobacteria_phage	6.2e-27	93.4
AWZ52092.1\|2131853_2132132_+	hypothetical protein	A0A0A7NRX5	Enterobacteria_phage	1.5e-33	78.3
AWZ52093.1\|2132143_2132386_+	DUF4754 domain-containing protein	A0A0A7NQ71	Enterobacteria_phage	2.3e-38	100.0
AWZ52094.1\|2132450_2133332_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.9e-114	92.6
AWZ52095.1\|2134904_2135864_+	recombinase	A0A0A7NPX4	Enterobacteria_phage	7.1e-179	98.4
AWZ52096.1\|2135868_2136180_+	chromosome partitioning protein	A0A0A7NPT5	Enterobacteria_phage	2.2e-41	83.5
AWZ52097.1\|2136544_2136814_+	hypothetical protein	NA	NA	NA	NA
AWZ52098.1\|2137376_2137901_+	hypothetical protein	NA	NA	NA	NA
AWZ52099.1\|2137915_2138962_-\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	1.9e-201	99.1
AWZ52100.1\|2138961_2140713_-	oxidoreductase	A0A0A7NV54	Enterobacteria_phage	0.0e+00	97.3
AWZ52101.1\|2140867_2141704_+\|capsid	phage capsid protein	A0A0A7NRY7	Enterobacteria_phage	2.7e-150	100.0
AWZ52102.1\|2141727_2142780_+\|capsid	phage major capsid protein, P2 family	A0A0A7NQ82	Enterobacteria_phage	1.3e-194	97.7
AWZ52103.1\|2142825_2143626_+\|terminase	terminase	A0A0A7NPX9	Enterobacteria_phage	6.6e-130	91.4
AWZ52104.1\|2143728_2144223_+\|capsid	capsid assembly protein	A0A0A7NPU2	Enterobacteria_phage	2.7e-89	99.4
AWZ52105.1\|2144222_2144423_+\|tail	phage tail protein	A0A0A7NV57	Enterobacteria_phage	3.5e-32	100.0
AWZ52106.1\|2144425_2144749_+\|holin	holin	A0A0A7NRY9	Enterobacteria_phage	1.6e-50	99.1
AWZ52107.1\|2144745_2145138_+	M15 family peptidase	A0A0A7NQ86	Enterobacteria_phage	5.8e-71	100.0
AWZ52108.1\|2145134_2145542_+	DUF2570 domain-containing protein	A0A0A7NPY2	Enterobacteria_phage	4.5e-66	98.5
AWZ55060.1\|2145513_2145693_+	hypothetical protein	NA	NA	NA	NA
AWZ52109.1\|2145679_2146147_+\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	1.0e-85	99.4
AWZ52110.1\|2146139_2146775_+	phage virion morphogenesis protein	A0A0A7NV60	Enterobacteria_phage	3.1e-114	99.5
AWZ52111.1\|2146771_2147353_+\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	1.0e-100	96.9
AWZ52112.1\|2147349_2147700_+\|plate	baseplate assembly protein	A0A0A7NQ90	Enterobacteria_phage	9.2e-60	100.0
AWZ52113.1\|2147703_2148600_+\|plate	baseplate assembly protein	A0A0A7NPY5	Enterobacteria_phage	1.1e-154	98.0
AWZ52114.1\|2148592_2149123_+\|tail	phage tail protein I	A0A0A7NPV1	Enterobacteria_phage	1.1e-93	99.4
AWZ52115.1\|2149125_2151258_+\|tail	phage tail protein	U5N099	Enterobacteria_phage	4.2e-131	66.7
AWZ52116.1\|2151257_2151836_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	1.7e-95	89.0
AWZ55061.1\|2151879_2152356_-	serine acetyltransferase	NA	NA	NA	NA
AWZ52117.1\|2152608_2153103_-\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	1.8e-85	98.8
AWZ52118.1\|2153109_2155917_-\|tail	phage tail tape measure protein	A0A0A7NRZ9	Enterobacteria_phage	0.0e+00	94.8
AWZ52119.1\|2155903_2156140_-\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	4.3e-21	94.1
AWZ52120.1\|2156067_2156442_-\|tail	phage tail protein	A0A0A7NPZ0	Enterobacteria_phage	6.9e-37	73.2
AWZ52121.1\|2156497_2157010_-\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	7.8e-92	98.2
AWZ52122.1\|2157009_2158194_-\|tail	phage tail sheath family protein	A0A0A7NV69	Enterobacteria_phage	8.1e-225	99.0
AWZ52123.1\|2158351_2159461_+	phage late control D family protein	A0A0A7NQ97	Enterobacteria_phage	9.6e-204	98.6
AWZ52124.1\|2159686_2161189_+	DNA-binding protein	NA	NA	NA	NA
AWZ52125.1\|2161432_2161693_+	hypothetical protein	NA	NA	NA	NA
AWZ52126.1\|2161883_2162024_+	Hok/Gef family protein	A0A0A7NPZ4	Enterobacteria_phage	4.5e-18	95.7
AWZ52127.1\|2162330_2162630_-	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	7.2e-13	40.0
AWZ52128.1\|2162634_2165022_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
AWZ52129.1\|2165036_2166020_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	1.4e-33	38.5
AWZ55062.1\|2166303_2166348_-\|tRNA	phenylalanyl--tRNA ligase operon leader peptide	NA	NA	NA	NA
AWZ52130.1\|2166470_2166827_-	50S ribosomal protein L20	NA	NA	NA	NA
AWZ52131.1\|2166879_2167077_-	50S ribosomal protein L35	NA	NA	NA	NA
AWZ52132.1\|2167173_2167716_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	6.3e-15	32.9
AWZ52133.1\|2167719_2169648_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	3.2e-130	37.4

DBSCAN-SWA_10

2389271 : 2476130

108

Enterobacteria_phage(35.48%)

capsid,lysis,transposase,terminase,holin,portal,head,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ52350.1\|2389271_2390485_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ52351.1\|2393006_2393804_-	AraC family transcriptional regulator	NA	NA	NA	NA
AWZ52352.1\|2393813_2394365_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
AWZ52353.1\|2394533_2394866_-	multidrug SMR transporter	NA	NA	NA	NA
AWZ52354.1\|2395199_2395514_-	flagellar hook-basal body complex protein FliE	NA	NA	NA	NA
AWZ52355.1\|2395727_2397386_+	flagellar basal body M-ring protein FliF	NA	NA	NA	NA
AWZ52356.1\|2397378_2398374_+	flagellar motor switch protein FliG	NA	NA	NA	NA
AWZ52357.1\|2398366_2399053_+	flagellar assembly protein FliH	NA	NA	NA	NA
AWZ52358.1\|2399052_2400426_+	flagellum-specific ATP synthase FliI	NA	NA	NA	NA
AWZ52359.1\|2400444_2400888_+	flagellar protein FliJ	NA	NA	NA	NA
AWZ52360.1\|2400884_2402012_+	flagellar hook length control protein FliK	NA	NA	NA	NA
AWZ52361.1\|2402116_2402581_+	flagellar basal body-associated protein FliL	NA	NA	NA	NA
AWZ52362.1\|2402585_2403590_+	flagellar motor switch protein FliM	NA	NA	NA	NA
AWZ52363.1\|2403586_2404000_+	flagellar motor switch protein FliN	NA	NA	NA	NA
AWZ52364.1\|2404002_2404368_+	flagellar protein FliO	NA	NA	NA	NA
AWZ52365.1\|2404367_2405105_+	flagellar biosynthetic protein FliP	NA	NA	NA	NA
AWZ52366.1\|2405114_2405384_+	flagellar biosynthetic protein FliQ	NA	NA	NA	NA
AWZ52367.1\|2405391_2406177_+	flagellar type III secretion system protein FliR	NA	NA	NA	NA
AWZ52368.1\|2406466_2407090_+	transcriptional regulator RcsA	NA	NA	NA	NA
AWZ52369.1\|2407133_2407376_-	hypothetical protein	NA	NA	NA	NA
AWZ52370.1\|2407484_2407712_+	DUF2525 domain-containing protein	NA	NA	NA	NA
AWZ52371.1\|2408009_2408825_+	mannosyl-3-phosphoglycerate phosphatase-related protein	NA	NA	NA	NA
AWZ52372.1\|2408821_2410516_-	cellulose biosynthesis regulator YedQ	A0A127AWB9	Bacillus_phage	1.3e-18	35.6
AWZ52373.1\|2410436_2410625_-	hypothetical protein	NA	NA	NA	NA
AWZ52374.1\|2410686_2410869_-	DUF2158 domain-containing protein	NA	NA	NA	NA
AWZ52375.1\|2410947_2411865_-	DUF808 domain-containing protein	NA	NA	NA	NA
AWZ52376.1\|2412037_2412958_+	drug/metabolite exporter YedA	NA	NA	NA	NA
AWZ52377.1\|2412946_2413417_-	very short patch repair endonuclease	E5E3X5	Burkholderia_phage	1.5e-33	47.6
AWZ52378.1\|2413397_2414816_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	1.8e-101	55.3
AWZ52379.1\|2414882_2415578_-	phosphohydrolase	A0A1D6Y7U0	Golden_Marseillevirus	2.1e-07	28.0
AWZ52380.1\|2415617_2415983_-	permease	NA	NA	NA	NA
AWZ52381.1\|2417397_2418611_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ52382.1\|2419616_2420468_+	Molecular chaperone Hsp31 and glyoxalase 3	NA	NA	NA	NA
AWZ52383.1\|2420575_2421934_-	HAMP domain-containing protein	NA	NA	NA	NA
AWZ55073.1\|2421933_2422605_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	5.4e-32	35.2
AWZ52384.1\|2422737_2423151_+	hydroxyisourate hydrolase	NA	NA	NA	NA
AWZ52385.1\|2423259_2424264_+	mononuclear molybdenum enzyme YedY	NA	NA	NA	NA
AWZ52386.1\|2424264_2424900_+	sulfoxide reductase heme-binding subunit YedZ	NA	NA	NA	NA
AWZ52387.1\|2425156_2425807_+	metal-binding protein ZinT	NA	NA	NA	NA
AWZ52388.1\|2426149_2426680_+	cytochrome b561	A0A0U2QLA7	Escherichia_phage	1.9e-56	100.0
AWZ52389.1\|2426702_2426945_+	hypothetical protein	NA	NA	NA	NA
AWZ52390.1\|2427914_2428901_-	peptidase M85	NA	NA	NA	NA
AWZ52391.1\|2429333_2429603_-\|tail	phage tail protein	A0A1U9AJC2	Stx1_converting_phage	2.7e-43	97.8
AWZ52392.1\|2429604_2430918_-\|tail	phage tail protein	A0A0P0ZCC1	Stx2-converting_phage	3.7e-77	97.0
AWZ52393.1\|2430982_2431582_-	Ail/Lom family protein	Q687E7	Enterobacteria_phage	8.8e-111	99.0
AWZ52394.1\|2431649_2435126_-	host specificity protein J	Q687E8	Enterobacteria_phage	0.0e+00	96.7
AWZ52395.1\|2435372_2436053_-\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	8.7e-115	98.2
AWZ52396.1\|2435950_2436694_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	3.3e-147	98.0
AWZ52397.1\|2436699_2437398_-\|tail	phage minor tail protein L	Q687F1	Enterobacteria_phage	4.7e-132	99.1
AWZ52398.1\|2437397_2437727_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
AWZ52399.1\|2437723_2440336_-\|tail	phage tail tape measure protein	Q687F3	Enterobacteria_phage	0.0e+00	96.0
AWZ52400.1\|2440316_2440730_-\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.2e-43	83.2
AWZ52401.1\|2440756_2441179_-\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	1.7e-71	98.6
AWZ52402.1\|2441192_2441945_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	4.9e-135	99.2
AWZ52403.1\|2441952_2442348_-\|tail	phage tail protein	A0A2R9YJI2	Escherichia_phage	1.5e-58	82.4
AWZ52404.1\|2442893_2443247_-\|tail	phage tail protein	A0A0K2FJB7	Enterobacteria_phage	1.5e-41	70.1
AWZ52405.1\|2443239_2443623_-	DNA-packaging protein FI	NA	NA	NA	NA
AWZ52406.1\|2443674_2444703_-\|capsid	minor capsid protein E	C6ZCY2	Enterobacteria_phage	3.6e-112	61.0
AWZ52407.1\|2444760_2445108_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	8.9e-23	58.1
AWZ52408.1\|2445144_2446650_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	3.0e-99	53.5
AWZ52409.1\|2446639_2448232_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	7.1e-184	60.9
AWZ52410.1\|2448228_2448435_-\|tail	phage tail protein	K7PM10	Enterobacteria_phage	7.9e-11	56.9
AWZ52411.1\|2448418_2450347_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	3.6e-262	66.4
AWZ55074.1\|2450318_2450825_-	DNA-packaging protein	O64316	Escherichia_phage	7.4e-34	47.3
AWZ52412.1\|2451251_2451476_+	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	1.3e-19	90.6
AWZ52413.1\|2451557_2451872_-	PerC family transcriptional regulator	NA	NA	NA	NA
AWZ52414.1\|2452112_2452253_-	hypothetical protein	NA	NA	NA	NA
AWZ52415.1\|2452335_2452803_-\|lysis	lysis protein	Q7AYI6	Enterobacteria_phage	5.5e-68	89.0
AWZ52416.1\|2452804_2453023_-	hypothetical protein	Q687G2	Enterobacteria_phage	1.0e-16	93.3
AWZ52417.1\|2453100_2453634_-	lysozyme	Q6H9V6	Enterobacteria_phage	1.9e-101	96.0
AWZ52418.1\|2453676_2454081_-	hypothetical protein	Q08JA0	Stx2-converting_phage	8.2e-52	83.5
AWZ52419.1\|2454064_2455278_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ52420.1\|2455509_2455725_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	7.7e-33	97.2
AWZ52421.1\|2455801_2456074_-	DUF826 domain-containing protein	A0A0P0ZBB8	Stx2-converting_phage	2.2e-21	100.0
AWZ52422.1\|2456114_2456294_-	DUF1378 domain-containing protein	A0A2R2Z345	Escherichia_phage	2.2e-25	100.0
AWZ52423.1\|2456431_2458369_-	DUF1737 domain-containing protein	Q6H9W1	Enterobacteria_phage	0.0e+00	96.4
AWZ52424.1\|2458417_2458546_-	hypothetical protein	NA	NA	NA	NA
AWZ52425.1\|2458847_2459279_-	tellurite resistance protein	H6WZJ6	Escherichia_phage	3.3e-67	97.2
AWZ52426.1\|2459366_2459792_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
AWZ52427.1\|2459788_2460139_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBY2	Stx2-converting_phage	3.1e-39	65.5
AWZ52428.1\|2460169_2461783_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	4.4e-181	64.0
AWZ52429.1\|2462268_2462982_-	AraC family transcriptional regulator	NA	NA	NA	NA
AWZ52430.1\|2463116_2463314_-	TrmB family transcriptional regulator	S5MQK8	Escherichia_phage	6.8e-28	98.5
AWZ52431.1\|2463537_2464092_-	antiterminator	A0A0U2S606	Escherichia_phage	8.0e-66	67.4
AWZ52432.1\|2464100_2464460_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	5.0e-37	63.5
AWZ52433.1\|2464472_2465522_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.2e-110	54.6
AWZ52434.1\|2465523_2465796_-	hypothetical protein	S4TNP0	Salmonella_phage	1.1e-12	53.0
AWZ52435.1\|2465917_2466262_-	TIGR00156 family protein	A0A1I9LJU6	Stx_converting_phage	6.1e-56	99.1
AWZ52436.1\|2466381_2466594_-	Hok/Gef family protein	A0A0P0ZAX5	Stx2-converting_phage	6.0e-30	100.0
AWZ52437.1\|2466827_2467385_-	DUF551 domain-containing protein	A0A0N7KZV3	Escherichia_phage	2.8e-34	41.7
AWZ52438.1\|2467386_2467605_-	sugar acetyltransferase inhibitor	A0A2R2Z311	Escherichia_phage	2.3e-21	72.2
AWZ52439.1\|2467732_2468044_-	hypothetical protein	A0A0U2QV73	Escherichia_phage	1.6e-55	91.3
AWZ52440.1\|2468036_2468264_-	hypothetical protein	A0A1B5FPG2	Escherichia_phage	5.1e-11	49.3
AWZ55075.1\|2468260_2468542_-	DNA-binding protein	A0A222YXX1	Escherichia_phage	1.0e-29	73.6
AWZ52441.1\|2468574_2469291_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	2.1e-71	62.6
AWZ52442.1\|2469312_2470059_-	DNA replication protein DnaC	A0A088CBP4	Shigella_phage	3.6e-114	83.2
AWZ52443.1\|2470065_2471136_-	phage replisome organizer	A0A088CD36	Shigella_phage	1.7e-64	65.7
AWZ52444.1\|2471207_2471633_-	Rha family transcriptional regulator	NA	NA	NA	NA
AWZ52445.1\|2471616_2471898_-	Cro/Cl family transcriptional regulator	K7PHA1	Enterobacteria_phage	8.5e-24	72.6
AWZ52446.1\|2471997_2472417_+	hypothetical protein	K7PK07	Enterobacteria_phage	4.0e-25	65.1
AWZ55076.1\|2472682_2472835_+	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	1.7e-07	53.2
AWZ52447.1\|2472846_2473485_+	hypothetical protein	A0A2R2Z306	Escherichia_phage	2.5e-07	41.9
AWZ55078.1\|2473485_2473695_-	hypothetical protein	NA	NA	NA	NA
AWZ55077.1\|2473743_2474004_-	hypothetical protein	NA	NA	NA	NA
AWZ52448.1\|2474265_2474454_+	cell division inhibition protein DicB	NA	NA	NA	NA
AWZ52449.1\|2474450_2474642_+	DUF1482 domain-containing protein	NA	NA	NA	NA
AWZ52450.1\|2474734_2475730_+	exonuclease	NA	NA	NA	NA
AWZ52451.1\|2475764_2476130_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_11

2714031 : 2775556

Enterobacteria_phage(23.08%)

capsid,lysis,transposase,holin,terminase,integrase

attL 2744610:2744645|attR 2776496:2776531

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ52657.1\|2714031_2714520_+\|terminase	terminase small subunit	A0A0P0ZCQ9	Stx2-converting_phage	3.9e-24	41.7
AWZ55091.1\|2714682_2715606_+\|capsid	phage major capsid protein	A0A0R6PHC6	Moraxella_phage	1.2e-13	24.9
AWZ52658.1\|2716070_2716295_-	autotransporter outer membrane beta-barrel domain-containing protein	NA	NA	NA	NA
AWZ52659.1\|2718691_2718949_-	hypothetical protein	NA	NA	NA	NA
AWZ52660.1\|2718980_2719628_+	DNA-binding response regulator	NA	NA	NA	NA
AWZ52661.1\|2719662_2720715_-	cytochrome c biogenesis protein CcmH	NA	NA	NA	NA
AWZ52662.1\|2720711_2721269_-	thiol:disulfide interchange protein	NA	NA	NA	NA
AWZ52663.1\|2721265_2723209_-	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
AWZ52664.1\|2723205_2723685_-	cytochrome c-type biogenesis protein CcmE	NA	NA	NA	NA
AWZ52665.1\|2723681_2723891_-	heme exporter protein D	NA	NA	NA	NA
AWZ52666.1\|2723887_2724625_-	heme exporter protein C	NA	NA	NA	NA
AWZ52667.1\|2724666_2725329_-	heme exporter protein CcmB	NA	NA	NA	NA
AWZ52668.1\|2725325_2725949_-	cytochrome c biogenesis ATP-binding export protein CcmA	G3M9Y6	Bacillus_virus	2.0e-12	25.5
AWZ52669.1\|2725961_2726564_-	cytochrome c-type protein NapC	NA	NA	NA	NA
AWZ52670.1\|2726573_2727023_-	nitrate reductase	NA	NA	NA	NA
AWZ52671.1\|2727019_2727883_-	quinol dehydrogenase ferredoxin subunit NapH	NA	NA	NA	NA
AWZ52672.1\|2727869_2728565_-	ferredoxin-type protein NapG	NA	NA	NA	NA
AWZ52673.1\|2728571_2731058_-	periplasmic nitrate reductase subunit alpha	NA	NA	NA	NA
AWZ52674.1\|2731054_2731318_-	protein NapD	NA	NA	NA	NA
AWZ52675.1\|2731307_2731802_-	ferredoxin-type protein NapF	NA	NA	NA	NA
AWZ52676.1\|2731901_2732075_+	hypothetical protein	NA	NA	NA	NA
AWZ52677.1\|2732210_2732699_+	ecotin	NA	NA	NA	NA
AWZ52678.1\|2732847_2734494_-	malate dehydrogenase (quinone)	NA	NA	NA	NA
AWZ52679.1\|2734711_2736355_-	microcin J25 efflux ABC transporter YojI	W8CYL7	Bacillus_phage	9.5e-14	24.0
AWZ52680.1\|2736430_2737081_-	DNA oxidative demethylase AlkB	A0A2K9L3R7	Tupanvirus	1.4e-05	31.7
AWZ52681.1\|2737080_2738145_-	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	1.8e-18	50.5
AWZ52682.1\|2738218_2739274_-	FAD:protein FMN transferase ApbE	NA	NA	NA	NA
AWZ52683.1\|2739385_2740477_-	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	9.4e-119	60.1
AWZ52684.1\|2740757_2740985_+	hypothetical protein	NA	NA	NA	NA
AWZ52685.1\|2740959_2741199_+	hypothetical protein	NA	NA	NA	NA
AWZ52686.1\|2741215_2743888_+	phosphotransferase RcsD	NA	NA	NA	NA
AWZ52687.1\|2743904_2744555_+	DNA-binding response regulator	NA	NA	NA	NA
2744610:2744645	attL	NA	NA	NA	NA
AWZ52688.1\|2744754_2747604_-	hybrid sensor histidine kinase/response regulator	A0A1V0SGX0	Hokovirus	1.4e-41	27.2
AWZ52689.1\|2747878_2748655_-	DUF2135 domain-containing protein	NA	NA	NA	NA
AWZ52690.1\|2748659_2750309_-	DUF2300 domain-containing protein	NA	NA	NA	NA
AWZ52691.1\|2750309_2754824_-	hypothetical protein	NA	NA	NA	NA
AWZ52692.1\|2755505_2756828_+	type III secretion system effector NleA	H6WZN2	Escherichia_phage	9.7e-227	85.5
AWZ52693.1\|2757521_2758055_-	DUF1076 domain-containing protein	B6DZC0	Enterobacteria_phage	6.4e-28	42.0
AWZ52694.1\|2758197_2759410_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ52695.1\|2759450_2759975_-	hypothetical protein	A0A0N7CEE8	Salmonella_phage	1.2e-84	89.7
AWZ52696.1\|2760124_2760562_-\|lysis	lysis protein	A0A0P0ZBQ9	Stx2-converting_phage	5.0e-71	97.9
AWZ52697.1\|2760558_2761056_-	lysozyme	A0A1B5FP97	Escherichia_phage	1.9e-90	98.2
AWZ55092.1\|2761055_2761271_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	4.5e-33	98.6
AWZ52698.1\|2761892_2762051_-	DUF3927 domain-containing protein	NA	NA	NA	NA
AWZ52699.1\|2763143_2763767_-	antitermination protein	K7PM87	Enterobacteria_phage	9.8e-113	98.6
AWZ52700.1\|2763763_2764429_-	serine/threonine protein phosphatase	Q5TJL8	Enterobacteria_phage	5.0e-131	99.5
AWZ52701.1\|2764425_2765028_-	recombination protein NinG	A0A1U9AJF8	Stx1_converting_phage	1.6e-91	94.6
AWZ52702.1\|2765002_2765569_-	endonuclease	A0A1U9AJK5	Stx1_converting_phage	6.6e-108	99.5
AWZ52703.1\|2766116_2767049_+	hypothetical protein	A0A1U9AJG3	Stx1_converting_phage	6.1e-151	99.7
AWZ52704.1\|2767087_2767915_+	hypothetical protein	A0A1U9AJG3	Stx1_converting_phage	1.6e-150	99.6
AWZ55093.1\|2768418_2768601_-	NinE family protein	A0A1U9AJF6	Stx1_converting_phage	1.1e-29	100.0
AWZ52705.1\|2768757_2769102_+	hypothetical protein	K7PJY7	Enterobacterial_phage	5.3e-60	100.0
AWZ52706.1\|2769207_2769426_+	excisionase	K7PKU2	Enterobacteria_phage	2.4e-34	98.6
AWZ52707.1\|2769403_2770474_+\|integrase	integrase	K7PHK0	Enterobacteria_phage	1.1e-196	98.0
AWZ52708.1\|2770468_2771095_-	DUF1175 domain-containing protein	NA	NA	NA	NA
AWZ52709.1\|2771091_2772780_-	DUF2138 domain-containing protein	NA	NA	NA	NA
AWZ52710.1\|2772928_2775556_-	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	8.1e-92	30.4
2776496:2776531	attR	NA	NA	NA	NA

DBSCAN-SWA_12

3125282 : 3209907

Enterobacteria_phage(68.52%)

lysis,transposase,terminase,portal,integrase,tRNA,tail

attL 3193264:3193279|attR 3216711:3216726

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ53024.1\|3125282_3126020_-\|tRNA	tRNA (adenosine(37)-N6)-methyltransferase TrmM	NA	NA	NA	NA
AWZ53025.1\|3126151_3127486_+	ATP-dependent RNA helicase SrmB	E3T5E1	Cafeteria_roenbergensis_virus	2.9e-45	30.8
AWZ53026.1\|3127695_3128577_-	LysR family transcriptional regulator	NA	NA	NA	NA
AWZ53027.1\|3128680_3129268_+	cysteine/O-acetylserine efflux protein	NA	NA	NA	NA
AWZ53028.1\|3129323_3129707_-	autonomous glycyl radical cofactor GrcA	Q7Y524	Enterobacteria_phage	1.4e-32	72.0
AWZ53029.1\|3130010_3130700_+	uracil-DNA glycosylase	A0A172DS90	Canid_alphaherpesvirus	7.1e-56	48.8
AWZ53030.1\|3130747_3131785_-	methyltransferase	NA	NA	NA	NA
AWZ53031.1\|3131774_3131978_-	hypothetical protein	NA	NA	NA	NA
AWZ53032.1\|3131991_3132411_+	thiol disulfide reductase thioredoxin	A0A0K2FIM3	Achromobacter_phage	2.8e-15	38.5
AWZ55103.1\|3132479_3133178_+	DTW domain-containing protein	NA	NA	NA	NA
AWZ53033.1\|3133209_3135870_+	protein lysine acetyltransferase	NA	NA	NA	NA
AWZ53034.1\|3135983_3137339_+	phosphatidylserine synthase	NA	NA	NA	NA
AWZ53035.1\|3137384_3137708_+	lipoprotein	NA	NA	NA	NA
AWZ53036.1\|3137704_3139003_-	alpha-ketoglutarate permease	Q6JIH2	Burkholderia_virus	1.3e-45	32.2
AWZ53037.1\|3138984_3139098_-	alpha-ketoglutarate permease	NA	NA	NA	NA
AWZ53038.1\|3144855_3147429_-	chaperone protein ClpB	H6X3M6	Enterobacteria_phage	2.6e-127	35.3
AWZ53039.1\|3147558_3148290_-	peptidoglycan editing factor PgeF	NA	NA	NA	NA
AWZ53040.1\|3148286_3149267_-	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
AWZ53041.1\|3149401_3150139_+	outer membrane protein assembly factor BamD	NA	NA	NA	NA
AWZ53042.1\|3150168_3150375_+	hypothetical protein	NA	NA	NA	NA
AWZ53043.1\|3150409_3150751_+	ribosome-associated inhibitor A	NA	NA	NA	NA
AWZ55104.1\|3150854_3150902_+	hypothetical protein	NA	NA	NA	NA
AWZ53044.1\|3151000_3152161_+	bifunctional chorismate mutase/prephenate dehydratase	NA	NA	NA	NA
AWZ53045.1\|3152203_3153325_-	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
AWZ53046.1\|3153335_3154406_-	3-deoxy-7-phosphoheptulonate synthase	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	5.3e-90	51.2
AWZ53047.1\|3154615_3154981_+	hypothetical protein	NA	NA	NA	NA
AWZ53048.1\|3155130_3155649_+	DUF4154 domain-containing protein	NA	NA	NA	NA
AWZ53049.1\|3155638_3156865_+	GGDEF domain-containing protein	NA	NA	NA	NA
AWZ53050.1\|3156880_3157363_+	hypothetical protein	NA	NA	NA	NA
AWZ53051.1\|3157439_3157787_-	50S ribosomal protein L19	NA	NA	NA	NA
AWZ53052.1\|3157828_3158596_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
AWZ53053.1\|3158626_3159175_-	ribosome maturation factor RimM	NA	NA	NA	NA
AWZ53054.1\|3159193_3159442_-	30S ribosomal protein S16	NA	NA	NA	NA
AWZ53055.1\|3159690_3161052_-	signal recognition particle protein	NA	NA	NA	NA
AWZ55105.1\|3161218_3162010_+	inner membrane protein YpjD	NA	NA	NA	NA
AWZ55106.1\|3162075_3163317_+	DUF21 domain-containing protein	NA	NA	NA	NA
AWZ53056.1\|3163371_3163965_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
AWZ53057.1\|3163961_3164156_-	molecular chaperone GrpE	NA	NA	NA	NA
AWZ53058.1\|3164087_3164966_+	NAD(+) kinase	NA	NA	NA	NA
AWZ53059.1\|3165051_3166713_+	DNA repair protein RecN	NA	NA	NA	NA
AWZ53060.1\|3166861_3167203_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
AWZ53061.1\|3167264_3167555_-	RnfH family protein	NA	NA	NA	NA
AWZ53062.1\|3167544_3168021_-	ubiquinone-binding protein	NA	NA	NA	NA
AWZ53063.1\|3168152_3168635_+	SsrA-binding protein	W5RAM5	Staphylococcus_phage	4.0e-29	46.8
AWZ53064.1\|3169483_3169732_+	DNA damage-inducible protein DinI	Q687E4	Enterobacteria_phage	2.4e-38	100.0
AWZ53065.1\|3170099_3170369_-\|tail	phage tail protein	Q687E5	Enterobacteria_phage	6.4e-45	100.0
AWZ53066.1\|3170370_3171693_-\|tail	phage tail protein	Q687E6	Enterobacteria_phage	3.7e-77	99.1
AWZ53067.1\|3171757_3172357_-	Ail/Lom family protein	Q687E7	Enterobacteria_phage	8.8e-111	99.0
AWZ53068.1\|3172424_3175901_-	host specificity protein J	Q687E8	Enterobacteria_phage	0.0e+00	96.7
AWZ53069.1\|3176147_3176828_-\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	8.7e-115	98.2
AWZ53070.1\|3176725_3177469_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	3.3e-147	98.0
AWZ53071.1\|3177474_3178173_-\|tail	phage minor tail protein L	Q687F1	Enterobacteria_phage	4.7e-132	99.1
AWZ53072.1\|3178172_3178502_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
AWZ53073.1\|3181050_3182263_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ53074.1\|3182266_3182413_-\|tail	phage tail protein	Q687G0	Enterobacteria_phage	3.5e-21	100.0
AWZ53075.1\|3182425_3183049_-\|tail	phage tail protein	Q8VNN3	Enterobacteria_phage	8.9e-106	100.0
AWZ53076.1\|3183051_3183333_-	DNA breaking-rejoining protein	Q8VNN4	Enterobacteria_phage	2.1e-46	100.0
AWZ53077.1\|3183325_3183652_-	DUF2190 domain-containing protein	Q9EYD5	Enterobacteria_phage	6.1e-50	100.0
AWZ55107.1\|3183739_3185695_-	peptidase S14	S5M7Q8	Escherichia_phage	0.0e+00	99.8
AWZ53078.1\|3185708_3187211_-\|portal	phage portal protein	Q9EYD2	Enterobacteria_phage	4.8e-291	100.0
AWZ53079.1\|3187210_3187447_-	hypothetical protein	Q687G1	Enterobacteria_phage	4.5e-34	100.0
AWZ53080.1\|3187419_3189543_-\|terminase	phage terminase large subunit family protein	Q9EYD1	Enterobacteria_phage	0.0e+00	100.0
AWZ53081.1\|3189539_3190016_-	DUF1441 domain-containing protein	Q8VNN8	Enterobacteria_phage	3.3e-84	100.0
AWZ53082.1\|3190428_3190896_-\|lysis	lysis protein	Q7AYI6	Enterobacteria_phage	7.7e-78	100.0
AWZ53083.1\|3191679_3191949_-	Shiga toxin Stx1 subunit B	Q7AYI7	Enterobacteria_phage	1.6e-43	100.0
AWZ53084.1\|3191958_3192906_-	Shiga toxin Stx1 subunit A	Q777W4	Enterobacteria_phage	1.6e-170	99.7
AWZ53085.1\|3193178_3193424_+	hypothetical protein	A0A0P0ZGS0	Escherichia_phage	5.0e-36	100.0
3193264:3193279	attL	NA	NA	NA	NA
AWZ53086.1\|3193412_3193847_-	antitermination protein	Q8VNP1	Enterobacteria_phage	4.3e-83	100.0
AWZ53087.1\|3193839_3194034_-	protein ninH	G9L694	Escherichia_phage	1.9e-30	100.0
AWZ53088.1\|3194030_3194636_-	recombination protein NinG	Q8VNP2	Enterobacteria_phage	1.9e-97	100.0
AWZ53089.1\|3195433_3196138_-	phage antirepressor Ant	Q8VNP5	Enterobacteria_phage	9.6e-133	100.0
AWZ53090.1\|3196412_3196595_-	NinE family protein	A0A0N7C1X3	Escherichia_phage	5.7e-29	100.0
AWZ53091.1\|3196591_3197119_-	phage N-6-adenine-methyltransferase	Q9EYC2	Enterobacteria_phage	1.6e-100	100.0
AWZ53092.1\|3197115_3197562_-	recombination protein NinB	Q8VNP6	Enterobacteria_phage	2.4e-81	100.0
AWZ53093.1\|3197518_3197944_-	restriction alleviation protein, Lar family	Q687G3	Enterobacteria_phage	1.4e-78	100.0
AWZ53094.1\|3198113_3198392_-	hypothetical protein	Q9EYB9	Enterobacteria_phage	4.4e-49	100.0
AWZ53095.1\|3198461_3198731_-	hypothetical protein	Q687G4	Enterobacteria_phage	8.4e-45	100.0
AWZ53096.1\|3198730_3200182_-	helicase DnaB	Q08J37	Stx2-converting_phage	7.7e-278	100.0
AWZ53097.1\|3200156_3201056_-	DNA replication protein	Q8VNP8	Enterobacteria_phage	1.6e-164	100.0
AWZ53098.1\|3201048_3201195_-	DUF2740 domain-containing protein	Q687G5	Enterobacteria_phage	1.1e-19	100.0
AWZ53099.1\|3201229_3201508_-	hypothetical protein	Q8VNP9	Enterobacteria_phage	3.6e-43	100.0
AWZ53100.1\|3201600_3202813_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ53101.1\|3203044_3203557_+	single-stranded DNA-binding protein	Q8VNQ1	Enterobacteria_phage	1.8e-75	100.0
AWZ53102.1\|3203570_3203864_+	RecBCD nuclease inhibitor	Q687G7	Enterobacteria_phage	8.5e-51	100.0
AWZ55108.1\|3203874_3204042_+	DUF2737 domain-containing protein	Q687G8	Enterobacteria_phage	3.0e-24	100.0
AWZ53103.1\|3204038_3204638_+	hypothetical protein	Q8VNQ2	Enterobacteria_phage	1.8e-111	100.0
AWZ53104.1\|3204639_3205911_+\|integrase	integrase	A0A1B5FPC6	Escherichia_phage	7.0e-182	100.0
AWZ53105.1\|3205949_3206366_+	hypothetical protein	A0A1B5FPM5	Escherichia_phage	1.1e-72	100.0
AWZ53106.1\|3206438_3208187_-	hypothetical protein	A0A1B5FPH1	Escherichia_phage	0.0e+00	99.8
AWZ55109.1\|3208188_3209907_-	ATP-binding protein	A0A1B5FPD5	Escherichia_phage	5.5e-307	99.7
3216711:3216726	attR	NA	NA	NA	NA

DBSCAN-SWA_13

3281435 : 3288575

Escherichia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ53174.1\|3281435_3283997_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.7e-30	20.6
AWZ53175.1\|3284102_3284759_+	serine/threonine protein phosphatase	A0A222YWF0	Escherichia_phage	5.6e-50	47.2
AWZ53176.1\|3284809_3285577_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	3.3e-70	56.7
AWZ53177.1\|3285772_3286681_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	3.0e-118	76.9
AWZ53178.1\|3286677_3287940_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	3.7e-135	61.4
AWZ53179.1\|3287936_3288575_+	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0

DBSCAN-SWA_14

4830867 : 4881238

Enterobacteria_phage(38.89%)

capsid,lysis,terminase,holin,head,integrase,tRNA,tail

attL 4872436:4872450|attR 4885180:4885194

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ54582.1\|4830867_4830990_+\|tRNA	tRNA-dihydrouridine synthase	NA	NA	NA	NA
AWZ54583.1\|4831118_4831652_+	hypothetical protein	K7PKJ4	Enterobacteria_phage	1.1e-99	100.0
AWZ54584.1\|4832069_4832330_-	pyocin activator protein PrtN	K7PGU0	Enterobacteria_phage	4.2e-41	98.8
AWZ54585.1\|4833787_4834540_+	antitermination protein	K7PGU5	Enterobacteria_phage	5.3e-137	99.2
AWZ54586.1\|4834625_4834835_-	hypothetical protein	A0A0P0ZGS0	Escherichia_phage	2.6e-25	98.4
AWZ54587.1\|4834849_4835002_+	DNA methylase	A0A2R2Z327	Escherichia_phage	3.4e-19	98.0
AWZ54588.1\|4835819_4837670_+	DUF1737 domain-containing protein	B6DZ89	Enterobacteria_phage	0.0e+00	96.9
AWZ54589.1\|4837964_4838111_-	hypothetical protein	NA	NA	NA	NA
AWZ54590.1\|4838109_4838325_+\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	7.7e-33	98.6
AWZ54591.1\|4838324_4838822_+	lysozyme	A0A0N7KZA0	Stx2-converting_phage	2.6e-92	100.0
AWZ54592.1\|4838818_4839286_+\|lysis	lysis protein	Q7AYI6	Enterobacteria_phage	4.0e-58	80.1
AWZ54593.1\|4839368_4839509_+	hypothetical protein	NA	NA	NA	NA
AWZ54594.1\|4839751_4840066_+	PerC family transcriptional regulator	NA	NA	NA	NA
AWZ54595.1\|4840966_4841530_+\|terminase	terminase small subunit	B6DZ97	Enterobacteria_phage	7.3e-83	94.1
AWZ54596.1\|4841526_4843188_+\|terminase	terminase large subunit	A0A0N7KZG0	Stx2-converting_phage	0.0e+00	98.7
AWZ54597.1\|4843251_4845189_+\|capsid	phage major capsid protein	H6WZL0	Escherichia_phage	0.0e+00	98.4
AWZ55168.1\|4845233_4845455_+	hypothetical protein	H6WZL1	Escherichia_phage	3.4e-36	100.0
AWZ54598.1\|4847818_4848145_+\|head,tail	phage gp6-like head-tail connector protein	B6ETF0	Enterobacteria_phage	7.0e-54	100.0
AWZ54599.1\|4848154_4848505_+\|head,tail	head-tail adaptor protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
AWZ54600.1\|4848501_4848948_+	hypothetical protein	A0A0P0ZCD2	Stx2-converting_phage	8.1e-77	100.0
AWZ54601.1\|4848944_4849289_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
AWZ54602.1\|4849355_4850072_+\|tail	phage tail protein	A0A0P0ZD29	Stx2-converting_phage	2.1e-127	98.3
AWZ54603.1\|4850077_4850452_+\|tail	phage tail protein	A0A0P0ZE84	Stx2-converting_phage	1.7e-64	99.2
AWZ54604.1\|4850475_4850757_+\|tail	phage tail protein	A0A0P0ZDE6	Stx2-converting_phage	1.3e-45	100.0
AWZ54605.1\|4850808_4854051_+\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	93.2
AWZ54606.1\|4854043_4854385_+\|tail	phage tail protein	A0A0P0ZCS8	Stx2-converting_phage	8.7e-63	100.0
AWZ54607.1\|4854384_4855083_+\|tail	phage minor tail protein L	H6WZM3	Escherichia_phage	3.1e-131	98.3
AWZ54608.1\|4855093_4855837_+\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	5.4e-150	99.2
AWZ54609.1\|4855734_4856415_+\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	2.0e-106	91.2
AWZ54610.1\|4856368_4856581_+	hypothetical protein	NA	NA	NA	NA
AWZ54611.1\|4856650_4860127_+\|tail	phage tail protein	Q6H9T2	Enterobacteria_phage	0.0e+00	96.0
AWZ55169.1\|4860195_4860819_+	hypothetical protein	A0A1U8QHD6	Enterobacteria_phage	1.1e-68	60.4
AWZ54612.1\|4860883_4862197_+\|tail	phage tail protein	A0A0P0ZD68	Stx2-converting_phage	3.3e-78	99.1
AWZ54613.1\|4862198_4862468_+\|tail	phage tail protein	B6DZB8	Enterobacteria_phage	2.4e-44	98.9
AWZ54614.1\|4862628_4863051_+	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	5.7e-72	97.0
AWZ54615.1\|4863181_4864240_-	type III effector	NA	NA	NA	NA
AWZ54616.1\|4864318_4864969_-	DUF1076 domain-containing protein	B6DZZ5	Stx2-converting_phage	2.8e-25	37.2
AWZ54617.1\|4865151_4865742_+	bfpT-regulated chaperone	NA	NA	NA	NA
AWZ55170.1\|4865728_4865848_-	ferredoxin	NA	NA	NA	NA
AWZ54618.1\|4866243_4866492_-	DNA damage-inducible protein DinI	A5LH55	Enterobacteria_phage	3.1e-38	98.8
AWZ54619.1\|4867740_4868778_+\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
AWZ54620.1\|4868911_4869154_+	envelope stress response protein PspG	NA	NA	NA	NA
AWZ54621.1\|4869319_4870303_-	quinone oxidoreductase	NA	NA	NA	NA
AWZ54622.1\|4870385_4871801_+	replicative DNA helicase	O80281	Escherichia_phage	4.8e-200	78.3
AWZ54623.1\|4871853_4872933_+	alanine racemase biosynthetic	A0A0P0YM39	Yellowstone_lake_mimivirus	5.2e-29	27.9
4872436:4872450	attL	NA	NA	NA	NA
AWZ54624.1\|4873185_4874379_+	aromatic amino acid transaminase	NA	NA	NA	NA
AWZ54625.1\|4874600_4875143_-	hypothetical protein	NA	NA	NA	NA
AWZ54626.1\|4875505_4876219_+	acid phosphatase AphA	NA	NA	NA	NA
AWZ54627.1\|4876329_4876746_+	thiamine phosphate synthase	NA	NA	NA	NA
AWZ54628.1\|4876749_4877106_+	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
AWZ54629.1\|4877140_4879963_-	excinuclease ABC subunit A	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	56.1
AWZ54630.1\|4879913_4880096_+	hypothetical protein	NA	NA	NA	NA
AWZ54631.1\|4880216_4880753_+	ssDNA-binding protein	A0A0A0P1Q9	Enterobacteria_phage	1.1e-56	78.7
AWZ54632.1\|4880851_4881133_-	hypothetical protein	NA	NA	NA	NA
AWZ54633.1\|4881091_4881238_+\|integrase	integrase	NA	NA	NA	NA
4885180:4885194	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP028430

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 15963

Salmonella_phage(71.43%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ55186.1\|0_1056_+	replication protein RepA	J9Q7H0	Salmonella_phage	5.4e-172	91.0
AWZ55187.1\|1402_2615_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ55188.1\|3027_3294_-	hypothetical protein	J9Q7G8	Salmonella_phage	2.6e-30	77.3
AWZ55189.1\|4049_5262_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ55190.1\|5611_6652_-	regulator	J9Q7Z3	Salmonella_phage	4.9e-117	89.9
AWZ55191.1\|6769_7201_-	hypothetical protein	J9Q6I8	Salmonella_phage	9.9e-64	83.9
AWZ55192.1\|7455_7680_+	hypothetical protein	J9Q735	Salmonella_phage	2.2e-14	56.9
AWZ55193.1\|7740_8304_+	DNA-binding protein	J9Q7G7	Salmonella_phage	1.3e-66	67.7
AWZ55194.1\|8633_8849_+	RNA chaperone/antiterminator CspA	A0A1W6JNX5	Morganella_phage	2.9e-24	77.1
AWZ55195.1\|9152_12722_-	DNA polymerase III subunit alpha	J9Q7Z2	Salmonella_phage	0.0e+00	93.0
AWZ55196.1\|12705_13919_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ55197.1\|13880_14651_+	hypothetical protein	J9Q741	Salmonella_phage	2.1e-101	81.4
AWZ55198.1\|14640_15384_+	hypothetical protein	J9Q6J5	Salmonella_phage	1.5e-51	47.2
AWZ55199.1\|15393_15963_+	hypothetical protein	J9Q7Z7	Salmonella_phage	1.1e-91	86.8

DBSCAN-SWA_2

20286 : 78973

Salmonella_phage(84.13%)

terminase,tRNA,tail,capsid,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ55202.1\|20286_21429_+	ribonucleotide-diphosphate reductase subunit beta	J9Q7H3	Salmonella_phage	2.6e-196	88.7
AWZ55203.1\|21506_22376_+	phosphoribosyl-ATP pyrophosphohydrolase	J9Q742	Salmonella_phage	5.3e-133	80.6
AWZ55302.1\|22523_23651_+	thymidylate synthase	J9Q6J6	Salmonella_phage	1.9e-191	86.6
AWZ55204.1\|23652_24066_+	hypothetical protein	J9Q7Z8	Salmonella_phage	2.3e-62	84.7
AWZ55205.1\|24062_24539_+	dihydrofolate reductase	J9Q7T1	Salmonella_phage	2.0e-81	90.5
AWZ55206.1\|24538_25183_+	hypothetical protein	J9Q7H4	Salmonella_phage	7.8e-97	81.3
AWZ55207.1\|25244_25664_+	hypothetical protein	J9Q743	Salmonella_phage	3.2e-51	71.9
AWZ55208.1\|25673_26231_+	3'-5' exonuclease	J9Q6J8	Salmonella_phage	1.7e-87	83.1
AWZ55209.1\|26389_27199_+	hypothetical protein	J9Q7Z9	Salmonella_phage	1.3e-64	53.2
AWZ55210.1\|27382_27976_+	phage N-6-adenine-methyltransferase	J9Q7T2	Salmonella_phage	2.0e-99	86.3
AWZ55211.1\|28161_28392_+	hypothetical protein	J9Q7H5	Salmonella_phage	2.0e-31	85.5
AWZ55212.1\|28976_29570_+	ribonuclease HI	J9Q745	Salmonella_phage	1.7e-93	83.8
AWZ55213.1\|29971_30223_+	hypothetical protein	NA	NA	NA	NA
AWZ55214.1\|30219_30417_+	hypothetical protein	J9Q800	Salmonella_phage	2.6e-11	56.9
AWZ55215.1\|30510_30936_+	tellurite/colicin resistance protein	Q71TK7	Escherichia_phage	2.8e-58	83.0
AWZ55216.1\|30935_31094_+	DUF3927 domain-containing protein	NA	NA	NA	NA
AWZ55217.1\|31233_31803_+	hypothetical protein	J9Q7H6	Salmonella_phage	1.4e-52	61.4
AWZ55218.1\|31858_32140_+	hypothetical protein	A0A0E3JPT1	Enterobacteria_phage	3.2e-39	76.3
AWZ55219.1\|32142_32757_+	hypothetical protein	A0A0E3GMH9	Enterobacteria_phage	1.2e-99	82.8
AWZ55220.1\|32860_34546_+	DUF4942 domain-containing protein	J9Q747	Salmonella_phage	0.0e+00	92.3
AWZ55221.1\|34607_35312_+	hypothetical protein	J9Q6K2	Salmonella_phage	7.2e-88	76.9
AWZ55222.1\|35311_35692_+	hypothetical protein	J9Q801	Salmonella_phage	5.9e-28	69.8
AWZ55223.1\|35830_36286_+	hypothetical protein	A0A222YY85	Escherichia_phage	1.2e-19	60.2
AWZ55224.1\|36282_36849_+	hypothetical protein	A0A222YWM9	Escherichia_phage	1.7e-42	59.5
AWZ55225.1\|36823_37009_+	hypothetical protein	NA	NA	NA	NA
AWZ55226.1\|37008_37926_+	DUF551 domain-containing protein	K7P7E4	Enterobacteria_phage	2.3e-46	44.2
AWZ55227.1\|38302_38929_+	hypothetical protein	C6ZR26	Salmonella_phage	3.3e-07	71.1
AWZ55228.1\|39397_39640_-	hypothetical protein	NA	NA	NA	NA
AWZ55229.1\|39730_40120_+	DNA repair protein	A0A077SK24	Escherichia_phage	8.6e-67	93.0
AWZ55230.1\|40157_41258_-	iron-sulfur cluster carrier protein ApbC	NA	NA	NA	NA
AWZ55231.1\|41415_43449_+\|tRNA	methionine--tRNA ligase	A0A1V0SEZ7	Hokovirus	2.2e-44	24.1
AWZ55303.1\|43688_43910_+	hypothetical protein	J9Q750	Salmonella_phage	1.9e-18	58.2
AWZ55232.1\|43946_44132_+	hypothetical protein	NA	NA	NA	NA
AWZ55233.1\|45787_46132_+	hypothetical protein	NA	NA	NA	NA
AWZ55234.1\|46385_46715_+	hypothetical protein	NA	NA	NA	NA
AWZ55235.1\|46868_47180_+	hypothetical protein	J9Q7T7	Salmonella_phage	5.7e-29	63.1
AWZ55236.1\|47306_47702_+	hypothetical protein	J9Q7I1	Salmonella_phage	1.2e-31	53.8
AWZ55237.1\|48540_48828_+	ABC transporter	J9Q753	Salmonella_phage	1.5e-36	77.4
AWZ55238.1\|49032_49515_+	hypothetical protein	J9Q805	Salmonella_phage	7.9e-62	69.8
AWZ55239.1\|50124_50352_-	hypothetical protein	A0A1S6KV93	Providencia_phage	2.5e-05	41.3
AWZ55240.1\|50372_50576_-	hypothetical protein	J9Q7I3	Salmonella_phage	5.9e-27	91.0
AWZ55241.1\|50625_51276_-	hypothetical protein	J9Q754	Salmonella_phage	1.1e-98	84.7
AWZ55242.1\|51571_52093_-	transcriptional regulator	J9Q6L0	Salmonella_phage	1.2e-66	79.7
AWZ55243.1\|52195_52996_+	hypothetical protein	A0A0M4QWT0	Salmonella_phage	6.0e-06	31.3
AWZ55244.1\|53381_53981_-	hypothetical protein	NA	NA	NA	NA
AWZ55245.1\|54013_54292_-	hypothetical protein	J9Q7T9	Salmonella_phage	4.6e-22	58.2
AWZ55246.1\|54294_55854_-	ATP-dependent helicase	J9Q7I4	Salmonella_phage	1.3e-278	92.9
AWZ55247.1\|55918_56617_+	chromosome partitioning protein ParB	J9Q756	Salmonella_phage	5.1e-110	87.1
AWZ55248.1\|56616_57285_+	chromosome partitioning protein ParB	J9Q6L1	Salmonella_phage	5.6e-106	89.6
AWZ55249.1\|57281_57947_+	adenylyl-sulfate kinase	J9Q807	Salmonella_phage	2.8e-110	98.6
AWZ55250.1\|57943_58834_+	hypothetical protein	J9Q7I6	Salmonella_phage	2.6e-167	98.6
AWZ55251.1\|58843_59110_+	hypothetical protein	J9Q757	Salmonella_phage	1.4e-36	88.6
AWZ55252.1\|59308_59941_+	DNA-binding protein	J9Q6D4	Salmonella_phage	1.2e-89	83.3
AWZ55253.1\|59940_61197_+\|terminase	terminase	J9Q7Y2	Salmonella_phage	7.5e-245	96.4
AWZ55254.1\|61223_62798_+	hypothetical protein	J9Q7R1	Salmonella_phage	2.4e-285	92.9
AWZ55255.1\|62819_63707_+	hypothetical protein	J9Q7F4	Salmonella_phage	1.1e-130	87.9
AWZ55256.1\|63732_64608_+\|capsid	phage major capsid protein	J9Q710	Salmonella_phage	1.5e-154	93.8
AWZ55257.1\|64681_65602_+	hypothetical protein	J9Q6D6	Salmonella_phage	1.3e-132	83.9
AWZ55258.1\|65646_66081_+	hypothetical protein	J9Q7Y3	Salmonella_phage	9.7e-59	81.2
AWZ55259.1\|66080_66914_+	hypothetical protein	J9Q7R2	Salmonella_phage	2.7e-142	92.4
AWZ55260.1\|66993_67338_+	hypothetical protein	J9Q7F6	Salmonella_phage	2.3e-55	95.6
AWZ55261.1\|67328_67802_+	hypothetical protein	J9Q711	Salmonella_phage	3.3e-76	90.4
AWZ55262.1\|67803_68187_+	hypothetical protein	J9Q6D8	Salmonella_phage	1.2e-57	82.7
AWZ55263.1\|68261_69008_+	hypothetical protein	J9Q7Y4	Salmonella_phage	2.4e-121	92.7
AWZ55264.1\|69063_69381_+	hypothetical protein	J9Q7R3	Salmonella_phage	8.6e-49	96.2
AWZ55265.1\|69461_69731_+	hypothetical protein	J9Q7F7	Salmonella_phage	1.7e-34	94.8
AWZ55266.1\|69738_74298_+\|tail	phage tail tape measure protein	J9Q712	Salmonella_phage	0.0e+00	80.0
AWZ55267.1\|74340_74676_+\|tail	phage tail protein	J9Q6E1	Salmonella_phage	1.8e-52	86.4
AWZ55268.1\|74725_75457_+\|tail	phage minor tail protein L	J9Q7Y5	Salmonella_phage	1.5e-133	96.6
AWZ55269.1\|75449_76247_+\|tail	phage tail protein	J9Q7R4	Salmonella_phage	1.9e-153	93.2
AWZ55304.1\|76234_76828_+\|tail	tail assembly protein	J9Q7F8	Salmonella_phage	3.4e-99	90.9
AWZ55270.1\|77760_78973_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7

DBSCAN-SWA_3

84341 : 104640

Salmonella_phage(88.89%)

tail,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ55271.1\|84341_87005_+\|tail	phage tail protein	J9Q6E3	Salmonella_phage	2.2e-68	39.2
AWZ55272.1\|87207_87531_+	hypothetical protein	J9Q6E7	Salmonella_phage	2.9e-44	88.8
AWZ55273.1\|87544_88237_+	hypothetical protein	J9Q7Y7	Salmonella_phage	1.8e-123	93.9
AWZ55274.1\|88238_88490_+	hypothetical protein	J9Q7R6	Salmonella_phage	2.0e-24	75.6
AWZ55275.1\|88440_88626_+	hypothetical protein	J9Q7G2	Salmonella_phage	4.9e-20	75.0
AWZ55276.1\|88658_89180_-	N-acetyltransferase	NA	NA	NA	NA
AWZ55306.1\|89187_89457_-	DUF1778 domain-containing protein	NA	NA	NA	NA
AWZ55277.1\|89699_90913_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ55278.1\|91088_91757_+	plasmid stability protein	J9Q7R7	Salmonella_phage	1.7e-110	91.4
AWZ55279.1\|91756_92116_+	hypothetical protein	J9Q7G3	Salmonella_phage	1.5e-44	97.9
AWZ55280.1\|92168_92936_-	hypothetical protein	NA	NA	NA	NA
AWZ55281.1\|93218_93959_+	hypothetical protein	J9Q7R8	Salmonella_phage	2.2e-127	89.6
AWZ55282.1\|94002_95343_+	DNA helicase	J9Q7G4	Salmonella_phage	9.8e-235	93.3
AWZ55283.1\|95424_96606_+	DNA primase	J9Q720	Salmonella_phage	3.5e-204	91.4
AWZ55284.1\|96597_97743_-	sel1 repeat family protein	NA	NA	NA	NA
AWZ55285.1\|97973_98387_+	hypothetical protein	A0A0M4QWT0	Salmonella_phage	3.9e-25	48.1
AWZ55286.1\|98512_99295_+	hypothetical protein	J9Q7Z0	Salmonella_phage	3.0e-58	43.4
AWZ55287.1\|99575_99833_+	hypothetical protein	J9Q7R9	Salmonella_phage	5.6e-14	56.6
AWZ55288.1\|99829_101152_+	DNA ligase	J9Q7G5	Salmonella_phage	3.4e-240	91.1
AWZ55289.1\|101148_101364_+	hypothetical protein	J9Q6I3	Salmonella_phage	9.7e-20	72.1
AWZ55290.1\|101509_101800_+	C-type natriuretic protein	J9Q7S1	Salmonella_phage	2.4e-37	79.2
AWZ55291.1\|103312_104221_-	hypothetical protein	NA	NA	NA	NA
AWZ55292.1\|104394_104640_+	GrxA family glutaredoxin	A0A2I7SAE2	Vibrio_phage	3.5e-13	44.9

DBSCAN-SWA_4

107984 : 116380

Salmonella_phage(83.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ55297.1\|107984_110093_+	cobalamin biosynthesis protein CobT	J9Q7G6	Salmonella_phage	2.5e-229	67.2
AWZ55298.1\|110188_111424_+	porphyrin biosynthesis protein	J9Q733	Salmonella_phage	2.0e-197	80.8
AWZ55299.1\|111668_112881_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
AWZ55308.1\|114162_114354_-	hypothetical protein	J9Q7H1	Salmonella_phage	3.7e-23	76.2
AWZ55300.1\|114395_115481_-	exonuclease	J9Q7S9	Salmonella_phage	8.0e-187	87.5
AWZ55301.1\|115735_116380_-	hypothetical protein	J9Q739	Salmonella_phage	2.9e-107	86.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP028431

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP028429

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. CP028430

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection