CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP024941	Paraburkholderia terricola strain mHS1 chromosome mHS1_A, complete sequence	1 crisprs	cas3,PD-DExK,WYL,DinG,csa3,DEDDh	0	0	5	0
CP024942	Paraburkholderia terricola strain mHS1 chromosome mHS1_B, complete sequence	3 crisprs	PD-DExK,RT,csa3,cas3,DinG	1	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP024941_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP024941_1

2342461-2342547

Orphan

Consensus_repeat	Method
AGCGCTTACTCCAACCCCATGCAACAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP024941_1

>merge|CP024941|1|2342461-2342547|CRISPRCasFinder
AGCGCTTACTCCAACCCCATGCAACATGCGCGTCGGTTGGAGTTAGCGCTTTAGCGCTTCAGCGCTTACTCCAATCCCATGCAACAT

>CP024941|1|1|2342461-2342547|CRISPRCasFinder
AGCGCTTACTCCAACCCCATGCAACAT	GCGCGTCGGTTGGAGTTAGCGCTTTAGCGCTTC
AGCGCTTACTCCAATCCCATGCAACAT

Protein	Signature genes	Signature genes Name	Protein_function
CP024941.1\|AXE94291.1\|2345594_2346986_-\|RIP-metalloprotease-RseP	unknown	unknown	gnl\|CDD\|182723
CP024941.1\|AXE92725.1\|2348209_2349031_-\|CDP-archaeol-synthase	unknown	unknown	gnl\|CDD\|366491
CP024941.1\|AXE92717.1\|2337841_2338603_-\|ribonuclease-HII	unknown	unknown	gnl\|CDD\|234574
CP024941.1\|AXE92727.1\|2349871_2350432_-\|ribosome-recycling-factor	unknown	unknown	gnl\|CDD\|178850
CP024941.1\|AXE92713.1\|2332561_2333023_-\|NfeD-family-protein	unknown	unknown	gnl\|CDD\|224501
CP024941.1\|AXE92719.1\|2339772_2340561_-\|acyl-ACP--UDP-N-acetylglucosamine-O-acyltransferase	unknown	unknown	gnl\|CDD\|235390
CP024941.1\|AXE92728.1\|2350532_2351246_-\|UMP-kinase	unknown	unknown	gnl\|CDD\|239787
CP024941.1\|AXE92714.1\|2333193_2335599_-\|phosphoenolpyruvate-synthase	unknown	unknown	gnl\|CDD\|235809
CP024941.1\|AXE92721.1\|2341308_2342421_-\|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase	unknown	unknown	gnl\|CDD\|234858
CP024941.1\|AXE92726.1\|2349024_2349807_-\|di-trans,poly-cis-decaprenylcistransferase	unknown	unknown	gnl\|CDD\|237831
CP024941.1\|AXE92722.1\|2342617_2343127_-\|outer-membrane-protein-chaperone	unknown	unknown	gnl\|CDD\|214922
CP024941.1\|AXE92723.1\|2343214_2345527_-\|outer-membrane-protein-assembly-factor-BamA	unknown	unknown	gnl\|CDD\|274514
CP024941.1\|AXE92712.1\|2331581_2332514_-\|SPFH/Band-7/PHB-domain-protein	unknown	unknown	gnl\|CDD\|223407
CP024941.1\|AXE92729.1\|2351466_2352348_-\|elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
CP024941.1\|AXE92718.1\|2338599_2339769_-\|lipid-A-disaccharide-synthase	unknown	unknown	gnl\|CDD\|234580
CP024941.1\|AXE92720.1\|2340659_2341124_-\|3-hydroxyacyl-[acyl-carrier-protein]-dehydratase-FabZ	unknown	unknown	gnl\|CDD\|234568
CP024941.1\|AXE92715.1\|2336126_2336942_+\|kinase/pyrophosphorylase	unknown	unknown	gnl\|CDD\|235419
CP024941.1\|AXE92716.1\|2336987_2337773_-\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|349968
CP024941.1\|AXE92724.1\|2346993_2348199_-\|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	unknown	unknown	gnl\|CDD\|235472
CP024941.1\|AXE92730.1\|2352563_2353316_-\|30S-ribosomal-protein-S2	unknown	unknown	gnl\|CDD\|235396

Protein	Function_ID	Function_description	E-value
CP024941.1\|AXE94291.1\|2345594_2346986_-\|RIP-metalloprotease-RseP	gnl\|CDD\|182723	PRK10779, PRK10779, sigma E protease regulator RseP.	2.63524e-114
CP024941.1\|AXE92725.1\|2348209_2349031_-\|CDP-archaeol-synthase	gnl\|CDD\|366491	pfam01148, CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases. The family includes phosphatidate cytidylyltransferase EC:2.7.7.41 as well as Sec59 from yeast. Sec59 is a dolichol kinase EC:2.7.1.108.	5.9371e-47
CP024941.1\|AXE92717.1\|2337841_2338603_-\|ribonuclease-HII	gnl\|CDD\|234574	PRK00015, rnhB, ribonuclease HII; Validated.	5.47613e-111
CP024941.1\|AXE92727.1\|2349871_2350432_-\|ribosome-recycling-factor	gnl\|CDD\|178850	PRK00083, frr, ribosome recycling factor; Reviewed.	3.02324e-110
CP024941.1\|AXE92713.1\|2332561_2333023_-\|NfeD-family-protein	gnl\|CDD\|224501	COG1585, COG1585, Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	1.26676e-10
CP024941.1\|AXE92719.1\|2339772_2340561_-\|acyl-ACP--UDP-N-acetylglucosamine-O-acyltransferase	gnl\|CDD\|235390	PRK05289, PRK05289, acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase.	3.00535e-159
CP024941.1\|AXE92728.1\|2350532_2351246_-\|UMP-kinase	gnl\|CDD\|239787	cd04254, AAK_UMPK-PyrH-Ec, UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and via gene repression of carbamoyl phosphate synthetase (the first enzyme of the pyrimidine biosynthesis pathway). The UMP kinase of E. coli (Ec) is known to function as a homohexamer, with GTP and UTP being allosteric effectors. Like other related enzymes (carbamate kinase, aspartokinase, and N-acetylglutamate kinase) the E. coli and most bacterial and chloroplast UMPKs (this CD) have a conserved, N-terminal, lysine residue proposed to function in the catalysis of the phosphoryl group transfer, whereas most archaeal UMPKs appear to lack this residue and the Pyrococcus furiosus structure has an additional Mg ion bound to the ATP molecule which is proposed to function as the catalysis instead. Members of this CD belong to the Amino Acid Kinase Superfamily (AAK).	3.48246e-144
CP024941.1\|AXE92714.1\|2333193_2335599_-\|phosphoenolpyruvate-synthase	gnl\|CDD\|235809	PRK06464, PRK06464, phosphoenolpyruvate synthase; Validated.	0
CP024941.1\|AXE92721.1\|2341308_2342421_-\|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase	gnl\|CDD\|234858	PRK00892, lpxD, UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional.	0
CP024941.1\|AXE92726.1\|2349024_2349807_-\|di-trans,poly-cis-decaprenylcistransferase	gnl\|CDD\|237831	PRK14836, PRK14836, undecaprenyl pyrophosphate synthase; Provisional.	1.13084e-136
CP024941.1\|AXE92722.1\|2342617_2343127_-\|outer-membrane-protein-chaperone	gnl\|CDD\|214922	smart00935, OmpH, Outer membrane protein (OmpH-like). This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.	1.66325e-34
CP024941.1\|AXE92723.1\|2343214_2345527_-\|outer-membrane-protein-assembly-factor-BamA	gnl\|CDD\|274514	TIGR03303, OM_YaeT, outer membrane protein assembly complex, YaeT protein. Members of this protein family are the YaeT protein of the YaeT/YfiO complex for assembling proteins into the outer membrane of Gram-negative bacteria. This protein is similar in sequence and function to a non-essential paralog, YtfM, that is also in the Omp85 family. Members of this family typically have five tandem copies of the surface antigen variable number repeat (pfam07244), followed by an outer membrane beta-barrel domain (pfam01103), while the YtfM family typically has a single pfam07244 repeat. [Protein fate, Protein and peptide secretion and trafficking].	0
CP024941.1\|AXE92712.1\|2331581_2332514_-\|SPFH/Band-7/PHB-domain-protein	gnl\|CDD\|223407	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones].	7.32025e-59
CP024941.1\|AXE92729.1\|2351466_2352348_-\|elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	2.62231e-152
CP024941.1\|AXE92718.1\|2338599_2339769_-\|lipid-A-disaccharide-synthase	gnl\|CDD\|234580	PRK00025, lpxB, lipid-A-disaccharide synthase; Reviewed.	0
CP024941.1\|AXE92720.1\|2340659_2341124_-\|3-hydroxyacyl-[acyl-carrier-protein]-dehydratase-FabZ	gnl\|CDD\|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	9.76663e-95
CP024941.1\|AXE92715.1\|2336126_2336942_+\|kinase/pyrophosphorylase	gnl\|CDD\|235419	PRK05339, PRK05339, pyruvate, phosphate dikinase/phosphoenolpyruvate synthase regulator.	1.49182e-134
CP024941.1\|AXE92716.1\|2336987_2337773_-\|RNA-methyltransferase	gnl\|CDD\|349968	cd18095, SpoU-like_rRNA-MTase, SAM-dependent rRNA methylase related to SpoU-TrmH. RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	6.46394e-57
CP024941.1\|AXE92724.1\|2346993_2348199_-\|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	gnl\|CDD\|235472	PRK05447, PRK05447, 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional.	0
CP024941.1\|AXE92730.1\|2352563_2353316_-\|30S-ribosomal-protein-S2	gnl\|CDD\|235396	PRK05299, rpsB, 30S ribosomal protein S2; Provisional.	3.04458e-162

>CP024941.1|AXE92721.1|2341308_2342421_-|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase
MAFTLEDIVQRFGGEVVGDGSQRVGSLAPLDQAGPDQLAFLANPKYLSQVETTRAGAVLINADDLAKLASRDARNFIVTPNPYAYFARVAQTFIDLASPKAVPGVHPSATIDPSAQIAASAVIGPHVTVEAGAVIGEHVRLDANVAIGRGTRIGAGSHLYPNVSVYHGCTLGERVIVHAGAVIGSDGFGFAPDFVGEGDARTGSWVKIPQVGGVSIAADVEIGANTTIDRGAMADTIIEECVKIDNLVQIGHNCKVGAYTVIAGCAGIAGSTTIGRHCMIGGAVGIAGHVTLADHVVVTAKSGVSKSLLKPGVYTSAFPAVNHADWNRSAALLRNIDKLRDRIKALENAAADKLDSAAGNEPGNSASEKA
>CP024941.1|AXE92720.1|2340659_2341124_-|3-hydroxyacyl-[acyl-carrier-protein]-dehydratase-FabZ
MSTEKINLDIHKILTLLPHRYPFLLVDRVLELEPHRSIKALKNVSINEPYFQGHFPTRPVMPGVLILEALAQTAALLTFSEEPSDPANTLYLFVGIDNARFKRVVEPGDQLILNCTFERHMRGIWKFKARAEVDGAVAAEADLMCAVRHTDKDA
>CP024941.1|AXE92719.1|2339772_2340561_-|acyl-ACP--UDP-N-acetylglucosamine-O-acyltransferase
MSRIHPTAIVEPGAQLDESVEIGPYAVIGAHVTIGARTTVGSHSVIEGHTTLGEDNRIGHYASVGGRPQDMKYKDEPTRLVIGNRNTIREFTTIHTGTVQDAGVTTLGDDNWIMAYVHIGHDCHVGSNVILSSNAQMAGHVTIGDHAIVGGMSGVHQFVRIGEHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSPDAISALRTAYRVLYKNGLSLEEAKVQLRELASAGGDGDAPVQTLLAFVEASQRGIIR
>CP024941.1|AXE92718.1|2338599_2339769_-|lipid-A-disaccharide-synthase
MALQPNPLRVAMVAGEPSGDLLAASLLDGLASRLPAATQYYGIGGPRMIATGFDAHWPMEKLSVRGYVEALRHIPGILAVRNELKRQLLAEPPAVFVGVDAPDFNFGLEHPLREAGIPTVHFVCPSIWAWRGGRIRKIAKAVDHMLCVFPFETALLEKAGVAASYVGHPLADEIPLEPDTLGARRTLGLAESGPIIAVLPGSRRSEIDLIGPTFFAAMEMMQHQEPGLRFVMPAATPALREMLRPLVDAHPGLALTITDGQAQLAMTAADAILVKSGTVTLEAALLKKPMVISYKVPWLTGQIMRRQGYLPYVGLPNILAGRFVVPEILQHFATPQALAEATLKQLRDESNRRALTEIFTEMHHVLKQNTAQRAAEVVASVIEQRKGRP
>CP024941.1|AXE92717.1|2337841_2338603_-|ribonuclease-HII
MTQSRAPRRKAATVAGAAAEQVGLNFETPDDIVCGVDEAGRGPLAGPVVAAAVIFDPSKPMIRGLDDSKALTAKKREELYDKIVDRALAYCIASATVEEIDTLNILHATMLAMKRAVEGLSVAPTLVKIDGNRCPTLSIRSEAVIGGDALVKCISAASILAKVTRDRMLLELHQTYPVYGFNAHVGYSTPQHLAALREHGPCEHHRRSFAPVREAHLRFGTGVPLPAGDVILPAMLDDDALLDDDAFGERSGA
>CP024941.1|AXE92716.1|2336987_2337773_-|RNA-methyltransferase
MKAITSRDNPLYKRLKALAGSTHQQRRGGHALLEGFHLASAYLDVAGQPELCIVTDGALRHDEAQAIVSRVDEHRLVTLPDALFGQLSNVVHGVGILLLVEKLDTPLPENVAQTCLVLDSVQDAGNVGSILRSAAAAGIQQVFCAPGTAYAWSSKVLRSGMGAHFLLQIHEDVEAQALIERLAIPVVITDSHGAEAIYDCDLSGPLAWVFGNEGAGVSQAWRDAVSLRVTIPQPGGMESLNVAAAAAVCVFEQCRQQRGRA
>CP024941.1|AXE92715.1|2336126_2336942_+|kinase/pyrophosphorylase
MPPTVFIVSDGTGITAETFAHSILSQFDQKFRLVRVPFVDSTEKAYATLEKINEAIQQDGRRPIVFTTLVDSASNQIVKGSNALVLDMFQTFVEPLEQELELKSSHAMGRGHQNADTEEYKNRIEAINFSLAHDDGQSNRNLADADVILVGVSRSGKTPTSLYLAMQYGVKAANYPLIPEDFERGKLPTPLLAHRQKMFGLSIDPQRLSEIRNERRPGSKYAAPENCRYEINEAEAMMRREGIKWLSSTHKSIEEIATTILQEIKLERSAY
>CP024941.1|AXE92714.1|2333193_2335599_-|phosphoenolpyruvate-synthase
MTNAVTVAKDKAYVVPFEQLRMTDVEIVGGKNASLGEMISQLAEAGVRVPTGFATTALAFRDFLHHNNLTERIAKRLETLDVDDVKALAEAGKEIRQWIVDAPLQPRLEADIRAGFDTLQNSSPEELSFAVRSSATAEDLPDASFAGQQESYLNVVGIDDVLDRMKHVFASLYNDRAISYRVHKGFTHAEVALSAGVQRMVRSDVGAAGVMFTLDTESGFKDAVFITSSYGLGETVVQGAVNPDEFYVYKTTLAQGKYPIIRRSIGSKLIKMEFTKAGEEGRVKTVDVPHEQRNRFSITDEDVIELAKYAVIIEKHYQRPMDIEWGKDGRDGKIFILQARPETVKSQATGKAEQRFKLKGQSNVLATGRAIGQKIGAGPVRVIHDPSEMDRVQPGDVLVADMTDPNWEPVMKRASAIVTNRGGRTCHAAIIARELGVPAVVGCGDATDVLKEGALVTVSCSEGDEGKIYDGLLETEITEVQRGELPPIPVKIMMNVGNPQLAFDFSQLPNAGVGLARLEFIINNNIGVHPKAILEYPNIDQDLKKAVESVARGHASPRAFYVDKLTEGIATIAAAFYPKPVIVRLSDFKSNEYKKLIGGSRYEPDEENPMLGFRGASRYIADDFAEAFQMECIALKKVREEMGLDNVEIMVPFVRTLKQAERVVGLLAKYGLKRGENGLRLIMMCEVPSNAILADEFLQFFDGFSIGSNDLTQLTLGLDRDSGMELLAVDFDERDPAVKFMLKRAIDTCLRLDKYVGICGQGPSDHPDFAQWLTDEGIKSISLNPDTIIETWQQLAKSSKK
>CP024941.1|AXE92713.1|2332561_2333023_-|NfeD-family-protein
MAPAGWFWWVGAGVLVVLELISGTFYLLMIALGFVAAAVAHLMGAAADAQFALAAGVALAAVLLLRRSGFGRRTRKEASKNPDVNLDIGQTLSVPAWHERRARVDYRGAAWDVELAAGEPEDAQVYEITELRGSCLIVVASPHARRKQKATAT
>CP024941.1|AXE92712.1|2331581_2332514_-|SPFH/Band-7/PHB-domain-protein
MDSTIIGAVFLVIVIVLAAQTIKIVPQQHAWVLERLGRYHRTLTPGLSFAFPFVDRIAYKHILKEIPLEVPSQVCITRDNTQLQVDGVLYFQVTDPMKASYGSSNFVFAITQLSQTTLRSVIGKLELDKTFEERDFINHSIVSSLDQAAANWGVKVLRYEIKDLTPPKEILHAMQAQITAEREKRALIAASEGRKQEQINIASGGREASIQKSEGERQAAINQAQGQAAAILAVAEANSQAIQKIAAAIQSNGGMEAVNLKVAEQYVNAFANLAKQGTTLIVPGNMSDMSSMIASALTIVNKGKGATDVR
>CP024941.1|AXE92722.1|2342617_2343127_-|outer-membrane-protein-chaperone
MFSKRVACALALAMTLGVGVAHAQEARIAAVNSDRILRESAAAKTAQIKLEAEFAKRDKDLADMAQKLKSMSDSLDKNGASMSPADRAQKQRDLSQLDTDFQRKQREFREDLNQRRNEELAAVLDRANKVIKQIAEQQHYDLIVQEAVYVSPRIDITDQVLKALAASGN
>CP024941.1|AXE92723.1|2343214_2345527_-|outer-membrane-protein-assembly-factor-BamA
MFKPHRFVPKTVIAAAFAAHGLVAHATSPFVVQDIRIEGLQRVEPGTVFAYLPIKQGDTFSDDKASEAIRALYATGFFNDVKIATEGNVVIVQVLERPAIGTIDFSGIHEFDKENLTKALRAVGLSQGRYYDKALVDKAEQELKRQYLTRGYYAAEVTTTITPIDRNRVSVLFSVAEGPSAKIRQINFIGNKAFSTGTLRDEMQLSTPNWFSWYTKNDLYAKDKLTGDLENVRSYYLNRGYLEFNIESTQVSITPDKKDMYLTVTLHEGEPYTISNIKLAGNLLDREAELNKLIKIKPGERFSAEKLQASTKAIVDKLGEYGYAFATVNAQPQIDQTNHKVDLTLQVDPSRRVYVRRINVVGNTRTRDEVVRREMRQLESSWFDSNRLALSKDRINRLGYFTDVDVTTIPVEGTPDQVDVDVKVAEKPTGAITLGAGFSSTDKVVLSAGVSQDNVFGSGTSLAVNVNTAKTYRTLTVTQVDPYFTVDGIKRITDVYYRTYQPLYYSTDSSFKIVTIGGDLKFGIPFSEVDTVYFGAGLEQNQLDVDSNTPASYKEYVKDFGRVSNNVPITVGWSRDARDSALVPSRGYFTQANAEYGTPIGGTQYYKADINAQYYYSFARGFVLGFNFQGGYGKGMGGKPYPIFKNYYAGGIGSVRGYEPSSLGPRDASTGDPIGGSKLLVGNIELTFPLPGTGYDRTLRVFTFLDAGNVWADASTAATSNGANGLRYGYGVGLAWISPIGPLKLSLGFPLTKHTGDQYQKFQFQIGTAF
>CP024941.1|AXE94291.1|2345594_2346986_-|RIP-metalloprotease-RseP
MNLLIELLAFAVAIGVLVVVHEYGHYSVARLCGVKVLRFSIGFGKPLFQWVSPKTGTEWTIAALPLGGYVKMLDERETGGAPIPAEALPHAFNRQSVGRRFAIVAAGPVANFLLAIVLFALVFATGVTEPAAVVAAPASNTPAAMAGFDGGETIVAARTENAGESEPVRSWSDLRWKLLGAAFDHKRVVLSAKDAHGTSEFQLDLRGITEKDVDDDFMSHLGFEPGGGKLTVAGVQPGSAAQQAGLTAGDRLRSVDGMSTDNATAFIAYVKSHAGKPMTLQVERGGAGAAAGKLAEIRIVPQAQRDDATGQQIGRIGAELSTQVPSIDVHYGPIESLQLGARRTWDLAVYSVRMFGRMIVGEASLKNLSGPVTIADYAGKSARLGPSAFLSFLALVSISLGVLNLLPIPVLDGGHLLYYLVEAVTGKVVSDRWQLVFQRAGLACIVALSAIALFNDLARLIHF
>CP024941.1|AXE92724.1|2346993_2348199_-|1-deoxy-D-xylulose-5-phosphate-reductoisomerase
MQKRLTLLGSTGSIGDSTLDVVARHPERFSVYALSAHRNGDKLAEQCLRFQPEVAVVGDADTAARVAAKLRAAGCKTEVTYGPQALVDVSKSDGCDTVVAAIVGAAGLAPSLAAARAGKRILLANKEALVMSGAIFMDAVRDNGAVLLPVDSEHNAIFQCLPREAALHGGVSKIILTASGGPFRTREPATLANITPEEACKHPNWVMGRKISVDSATMMNKGLEVIEAHWLFGLPGERIDVLIHPQSVIHSLVSYADGSVLAQLGNPDMRTPIAHALAFPDRVDSGVAQLDLAEIASLSFEKPDYARFPCLALAMKALAAGGVASAALNAANEIAVEAFLSRQIGFMKIAEVVEAVLNALPNRSAHVLEDVIEADAAARRAAAELIARLPDGARRTERAVQ
>CP024941.1|AXE92725.1|2348209_2349031_-|CDP-archaeol-synthase
MLRTRVITAIILLAVFLPVTLFAPVGAFGALIAFVVVFAAWEWARLLKLGGAGPVIYALVAAVALVASTWLGAGVEKPRPLFQAAAIFWLIAGPYVLLRKPALAQGAWRAFLFLAGIVVFVACWHALVAARMKGVPFVLSLLLLVWLADIGAYFSGKAFGKHKLAPAISPGKTWEGAIGGWLVVMIVAAAAVFLQAFEPTLYSALLAQLGAVRTLLALTLLVAFSVVGDLFESMLKRQAGVKDSSGLLPGHGGVLDRIDALLPVLPLAMLLLG
>CP024941.1|AXE92726.1|2349024_2349807_-|di-trans,poly-cis-decaprenylcistransferase
MTYTSSTVRVPDVAAVPRHIAIIMDGNGRWATQRRLPRVAGHTRGVDAVRAAVEACARQGVEYLTLFAFSSENWRRPNDEVSFLMRLFVTALEREIGKLHANGIRLRVVGDLSKFDTRIRDLIKRAESKTARNTRLTLTIAANYGGRWDIMQATRKLAEQSALAGKAVEINEESFAEHLSMAYAPEPDLFIRTGGERRVSNFLLWQLAYTEFYFTDTFWPDFDADALGHAIASYAERERRFGRTSAQLEPQSQNVDSLPC
>CP024941.1|AXE92727.1|2349871_2350432_-|ribosome-recycling-factor
MSVADIRKGAEQKMQRSIDAFKNDLSKIRTGRAHTGLLDHIQCDYYGSPVPISQVANLTLIDARTIGVQPWEKKMVQVVEKAIRESDLGLNPATQGDVIRVPMPALTEERRRELTKVVKSEAETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRAGDDIQKLTDKFVAEIDKLVVTKEAEIMTV
>CP024941.1|AXE92728.1|2350532_2351246_-|UMP-kinase
MPIAYKRVLLKLSGEALMGDDAFGINRATIERMVADVAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGSEIGAEVVLKATKVDGVYSADPKKDPSATRYTTISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSIVKPGALKRIVQGEDEGTLVHV
>CP024941.1|AXE92729.1|2351466_2352348_-|elongation-factor-Ts
MAAITASMVAELRAKTDAPMMECKKALTEADGDMARAEELLRVKLGNKASKAASRVTAEGVVASFIGGNAGSLVELNCETDFVSKNDDFLAFSKKVAELVATQNPADVAALAALPLDGQTVDAVRLALVGKIGENLSIRRFVRFETPNKLAAYLHGTRIGVLVEYTGADEQVGKDVAMHIAAMKPVSLSSDDVPADLIAKERSIAEQKAAESGKPAEIVAKMVDGSVQKYLKEVSLLNQTFVKNDKQTIEQMLKAGNASVQKFALFVVGEGIEKKQDDFAAEVAAQVAAAKQQ
>CP024941.1|AXE92730.1|2352563_2353316_-|30S-ribosomal-protein-S2
MAVTMRQMLEAGVHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMYNDALKYARQLAANRGTILFVGTKRQSRDTIAEEAQRAGMPYVNARWLGGMLTNFKTLKVSIKRLKDMEAALEAGETERMSKKEALLFEREMAKLQKSIGGVKDMGGIPDAIFVVDVGYHKIAVTEANKLGVPVIAVVDTNHSPEGIDYVIPGNDDASKAVALYTAGVADAILEGRANAVNEVVQAARGGDGDEFVEVNSEA

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

966702 : 1014587

uncultured_Caudovirales_phage(32.35%)

terminase,head,portal,integrase,tail,capsid,transposase,plate

attL 976976:976995|attR 1023879:1023898

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXE94146.1\|966702_967809_+\|transposase	transposase	NA	NA	NA	NA
AXE91666.1\|967997_968219_+	hypothetical protein	NA	NA	NA	NA
AXE91667.1\|968370_968583_+	hypothetical protein	NA	NA	NA	NA
AXE91668.1\|968794_970222_+	alpha,alpha-trehalose-phosphate synthase (UDP-forming)	NA	NA	NA	NA
AXE91669.1\|970402_971848_-	MFS transporter	NA	NA	NA	NA
AXE91670.1\|971985_972489_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
AXE91671.1\|972650_973097_-	very short patch repair endonuclease	E5E3X5	Burkholderia_phage	1.5e-62	75.7
AXE91672.1\|973139_974426_-	DNA (cytosine-5-)-methyltransferase	E5E3X6	Burkholderia_phage	7.0e-206	80.9
AXE91673.1\|974699_975026_-	hypothetical protein	NA	NA	NA	NA
AXE91674.1\|975189_975381_+	CsbD family protein	NA	NA	NA	NA
AXE91675.1\|975573_975795_+	hypothetical protein	NA	NA	NA	NA
AXE91676.1\|976002_976707_+	glutathione S-transferase	NA	NA	NA	NA
976976:976995	attL	NA	NA	NA	NA
AXE91677.1\|977008_978028_+\|integrase	site-specific integrase	A0A1B1P9F9	Acinetobacter_phage	3.7e-69	42.6
AXE94147.1\|978103_978256_+	hypothetical protein	NA	NA	NA	NA
AXE91678.1\|978274_978583_-	hypothetical protein	NA	NA	NA	NA
AXE91679.1\|978646_979414_-	dinucleotide-utilizing protein	NA	NA	NA	NA
AXE91680.1\|979766_980558_-	jamm isopeptidase	NA	NA	NA	NA
AXE91681.1\|980561_981272_-	hypothetical protein	NA	NA	NA	NA
AXE91682.1\|981268_982336_-	hypothetical protein	NA	NA	NA	NA
AXE91683.1\|982520_982904_-	hypothetical protein	NA	NA	NA	NA
AXE91684.1\|982915_983443_-	hypothetical protein	NA	NA	NA	NA
AXE91685.1\|983469_983703_-	hypothetical protein	E5FFF4	Burkholderia_phage	1.7e-14	54.8
AXE91686.1\|983712_984003_-	hypothetical protein	Q546W6	Burkholderia_phage	1.6e-25	61.5
AXE91687.1\|984005_984212_-	hypothetical protein	C7BGF3	Burkholderia_phage	1.8e-18	75.4
AXE91688.1\|984347_984539_-	hypothetical protein	NA	NA	NA	NA
AXE94148.1\|984812_985538_-	LexA family transcriptional repressor	A0A0R6PHL1	Moraxella_phage	1.5e-27	34.7
AXE91689.1\|986117_986627_+	hypothetical protein	C7BGG0	Burkholderia_phage	7.1e-53	69.0
AXE91690.1\|986654_988022_+	replicative DNA helicase	C7BGG1	Burkholderia_phage	1.0e-191	73.6
AXE94149.1\|988064_989084_+	helix-turn-helix domain-containing protein	C7BGG2	Burkholderia_phage	2.8e-93	55.0
AXE91691.1\|989101_989509_+	hypothetical protein	C7BGG3	Burkholderia_phage	3.6e-31	53.5
AXE91692.1\|990225_992313_+\|terminase	terminase	A0A2D1GMT1	Marinobacter_phage	1.8e-174	51.5
AXE91693.1\|992335_992542_+	hypothetical protein	NA	NA	NA	NA
AXE91694.1\|992538_994050_+\|portal	phage portal protein	A0A2H4JFL5	uncultured_Caudovirales_phage	1.2e-143	53.5
AXE91695.1\|994050_995211_+	peptidase S14	S5M7Q8	Escherichia_phage	4.4e-42	43.3
AXE91696.1\|995247_995589_+\|head	head decoration protein	A0A2H4JF15	uncultured_Caudovirales_phage	1.3e-21	55.3
AXE91697.1\|995664_996663_+\|capsid	major capsid protein	A0A2H4J890	uncultured_Caudovirales_phage	6.6e-111	60.3
AXE91698.1\|996673_996970_+	hypothetical protein	NA	NA	NA	NA
AXE91699.1\|996982_997522_+\|tail	phage tail protein	A0A2H4JBV1	uncultured_Caudovirales_phage	3.4e-13	29.0
AXE91700.1\|997511_998039_+	hypothetical protein	Q9JML9	Wolbachia_phage	7.2e-24	41.9
AXE91701.1\|998043_998727_+\|plate	phage baseplate assembly protein V	A0A2H4JG06	uncultured_Caudovirales_phage	6.7e-14	35.8
AXE91702.1\|998804_999035_+	hypothetical protein	NA	NA	NA	NA
AXE91703.1\|999037_999382_+\|plate	phage baseplate protein	A0A193GYY8	Enterobacter_phage	5.5e-17	44.9
AXE91704.1\|999378_1000281_+\|plate	baseplate J protein	D5LGZ3	Escherichia_phage	9.1e-51	39.7
AXE91705.1\|1000273_1000837_+\|tail	phage tail protein I	A4JWL7	Burkholderia_virus	1.3e-36	56.2
AXE91706.1\|1000848_1001904_+	hypothetical protein	Q6QI97	Burkholderia_phage	1.1e-52	48.4
AXE91707.1\|1001912_1002356_+\|tail	phage tail protein	NA	NA	NA	NA
AXE91708.1\|1002485_1003655_+\|tail	phage tail protein	A0A2H4J869	uncultured_Caudovirales_phage	1.8e-163	75.0
AXE91709.1\|1003679_1004183_+\|tail	phage major tail tube protein	Q7M2A5	Pseudomonas_phage	3.7e-46	54.5
AXE94150.1\|1004265_1004607_+\|tail	phage tail assembly protein	A0A2H4J873	uncultured_Caudovirales_phage	1.3e-10	39.4
AXE91710.1\|1004705_1007138_+\|tail	phage tail tape measure protein	A0A2H4JG00	uncultured_Caudovirales_phage	8.7e-56	33.3
AXE91711.1\|1007146_1008028_+	oxidoreductase	A0A2H4J875	uncultured_Caudovirales_phage	9.2e-32	35.9
AXE94151.1\|1008002_1008209_+\|tail	phage tail protein	A0A2H4J9Z9	uncultured_Caudovirales_phage	3.8e-13	55.2
AXE91712.1\|1008217_1009270_+	late control protein	A0A2H4JBF6	uncultured_Caudovirales_phage	4.9e-80	48.5
AXE91713.1\|1009363_1009825_+	hypothetical protein	NA	NA	NA	NA
AXE91714.1\|1009821_1010373_+	hypothetical protein	A0A0E3JI96	Rhodoferax_phage	1.1e-51	57.5
AXE91715.1\|1010369_1010987_+	hypothetical protein	A0A0E3M0Y2	Rhodoferax_phage	1.3e-11	47.2
AXE91716.1\|1011212_1012004_+	restriction endonuclease subunit M	Q8W6S4	Burkholderia_virus	3.7e-133	82.1
AXE91717.1\|1012103_1012358_-	hypothetical protein	NA	NA	NA	NA
AXE91718.1\|1012637_1013360_-	hypothetical protein	NA	NA	NA	NA
AXE94152.1\|1013615_1014587_-	NAD-dependent epimerase	A0A2H4UUK0	Bodo_saltans_virus	3.2e-25	27.9
1023879:1023898	attR	NA	NA	NA	NA

DBSCAN-SWA_2

2499865 : 2605569

uncultured_Caudovirales_phage(30.95%)

terminase,head,tRNA,protease,tail,portal,integrase,capsid,transposase,plate

attL 2538361:2538391|attR 2588938:2588968

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXE92812.1\|2499865_2500819_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
AXE92813.1\|2500914_2501280_-	ribosome-binding factor A	NA	NA	NA	NA
AXE92814.1\|2501481_2504427_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	3.8e-21	24.9
AXE92815.1\|2504521_2505997_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
AXE92816.1\|2505993_2506452_-	ribosome maturation factor RimP	NA	NA	NA	NA
AXE92817.1\|2506970_2508851_-	23S rRNA pseudouridylate synthase B	NA	NA	NA	NA
AXE92818.1\|2508914_2510081_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	3.3e-21	34.1
AXE92819.1\|2510442_2511666_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
AXE92820.1\|2511791_2512694_-	LysR family transcriptional regulator	NA	NA	NA	NA
AXE92821.1\|2513097_2513499_+	hypothetical protein	NA	NA	NA	NA
AXE92822.1\|2513787_2514042_+	hypothetical protein	NA	NA	NA	NA
AXE92823.1\|2514416_2514740_-	hypothetical protein	NA	NA	NA	NA
AXE92824.1\|2514937_2515726_+	hypothetical protein	NA	NA	NA	NA
AXE92825.1\|2515976_2516222_+	hypothetical protein	NA	NA	NA	NA
AXE92826.1\|2516559_2516817_+	DNA-binding protein	NA	NA	NA	NA
AXE92827.1\|2516881_2517172_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
AXE92828.1\|2517743_2519039_+	diguanylate phosphodiesterase	NA	NA	NA	NA
AXE92829.1\|2519035_2519440_-\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
AXE92830.1\|2519552_2521742_-	exodeoxyribonuclease V subunit alpha	A0A1P8DII4	Virus_Rctr197k	3.7e-13	25.4
AXE92831.1\|2521738_2525443_-	exodeoxyribonuclease V subunit beta	S5M596	Bacillus_phage	3.5e-08	30.8
AXE92832.1\|2525439_2528814_-	exodeoxyribonuclease V subunit gamma	NA	NA	NA	NA
AXE92833.1\|2529016_2531521_+	AraE protein	NA	NA	NA	NA
AXE92834.1\|2531681_2531891_-	hypothetical protein	NA	NA	NA	NA
AXE92835.1\|2532299_2533259_+	hypothetical protein	D1LW79	Prochlorococcus_phage	4.1e-17	26.2
AXE92836.1\|2533267_2534257_+	hypothetical protein	A0A2P1ELT8	Moumouvirus	4.7e-08	24.4
AXE92837.1\|2534295_2536245_+	glycosyltransferase	NA	NA	NA	NA
AXE92838.1\|2536398_2537496_-\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AXE92839.1\|2537588_2538389_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
2538361:2538391	attL	NA	NA	NA	NA
AXE92840.1\|2539472_2541485_+	adhesin	NA	NA	NA	NA
AXE92841.1\|2543392_2543632_-	hypothetical protein	NA	NA	NA	NA
AXE92842.1\|2543955_2545053_-\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AXE92843.1\|2545350_2546118_-	AAA family ATPase	K4HZD4	Acidithiobacillus_phage	3.0e-71	54.6
AXE92844.1\|2546130_2547654_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	5.5e-149	52.4
AXE92845.1\|2548105_2549614_+	hypothetical protein	NA	NA	NA	NA
AXE92846.1\|2549877_2550876_+	hypothetical protein	NA	NA	NA	NA
AXE92847.1\|2552200_2552608_+	PAAR domain-containing protein	Q8W6S2	Burkholderia_virus	1.9e-16	53.4
AXE92848.1\|2552612_2553116_+	hypothetical protein	A4PE24	Ralstonia_virus	4.2e-21	41.2
AXE92849.1\|2553463_2554072_+	hypothetical protein	NA	NA	NA	NA
AXE92850.1\|2554084_2554795_+	LysR family transcriptional regulator	A4PE26	Ralstonia_virus	9.3e-35	38.5
AXE92851.1\|2554834_2555629_-	restriction endonuclease subunit M	Q8W6S4	Burkholderia_virus	4.6e-139	87.5
AXE92852.1\|2556448_2557000_-	hypothetical protein	A0A0E3JI96	Rhodoferax_phage	4.7e-50	57.5
AXE92853.1\|2556996_2557458_-	hypothetical protein	NA	NA	NA	NA
AXE92854.1\|2557552_2558605_-	late control protein	A0A2H4JBF6	uncultured_Caudovirales_phage	1.4e-79	47.6
AXE92855.1\|2558614_2558821_-\|tail	phage tail protein	A0A2H4J9Z9	uncultured_Caudovirales_phage	4.9e-13	55.2
AXE92856.1\|2558795_2559677_-	oxidoreductase	A0A2H4J875	uncultured_Caudovirales_phage	2.7e-31	36.3
AXE92857.1\|2559685_2562145_-\|tail	phage tail protein	A0A2H4JG00	uncultured_Caudovirales_phage	1.2e-57	34.1
AXE94305.1\|2562268_2562568_-\|tail	phage tail assembly protein	A0A2H4J873	uncultured_Caudovirales_phage	5.2e-11	40.4
AXE92858.1\|2562700_2563204_-\|tail	phage major tail tube protein	Q7M2A5	Pseudomonas_phage	3.7e-46	54.5
AXE92859.1\|2563227_2564409_-\|tail	phage tail protein	A0A2H4J869	uncultured_Caudovirales_phage	6.7e-163	74.5
AXE92860.1\|2564504_2564939_-\|tail	phage tail protein	NA	NA	NA	NA
AXE92861.1\|2564947_2566003_-	hypothetical protein	Q6QI97	Burkholderia_phage	5.6e-52	39.8
AXE92862.1\|2566014_2566578_-\|tail	phage tail protein I	A4JWL7	Burkholderia_virus	1.8e-36	55.5
AXE92863.1\|2566570_2567464_-\|plate	baseplate J protein	D5LGZ3	Escherichia_phage	9.0e-51	39.3
AXE92864.1\|2567460_2567805_-\|plate	phage baseplate protein	A0A193GYY8	Enterobacter_phage	2.8e-16	43.9
AXE92865.1\|2567807_2568020_-	hypothetical protein	NA	NA	NA	NA
AXE92866.1\|2568129_2568483_-	hypothetical protein	NA	NA	NA	NA
AXE92867.1\|2568730_2569408_-\|plate	phage baseplate assembly protein V	A0A2H4JG06	uncultured_Caudovirales_phage	8.7e-14	37.3
AXE92868.1\|2569412_2569940_-	hypothetical protein	Q9JML9	Wolbachia_phage	5.0e-25	43.4
AXE92869.1\|2569929_2570469_-\|tail	phage tail protein	A0A2H4JBV1	uncultured_Caudovirales_phage	3.8e-12	28.5
AXE92870.1\|2570506_2570803_-	hypothetical protein	NA	NA	NA	NA
AXE92871.1\|2570813_2571809_-\|capsid	major capsid protein E	A0A2H4J890	uncultured_Caudovirales_phage	6.6e-119	63.2
AXE92872.1\|2571886_2572231_-\|head	head decoration protein	A0A2H4JF15	uncultured_Caudovirales_phage	1.3e-21	55.8
AXE92873.1\|2572272_2573472_-	peptidase S14	S5M7Q8	Escherichia_phage	6.6e-41	42.4
AXE94306.1\|2573472_2574942_-\|portal	phage portal protein	A0A2H4JFL5	uncultured_Caudovirales_phage	2.2e-139	53.2
AXE92874.1\|2574992_2575199_-	hypothetical protein	NA	NA	NA	NA
AXE92875.1\|2575221_2577333_-\|terminase	terminase	A0A2D1GMT1	Marinobacter_phage	7.0e-171	50.6
AXE92876.1\|2578130_2578883_-	hypothetical protein	NA	NA	NA	NA
AXE92877.1\|2579153_2581685_-	virulence protein E	A0A2D1GN57	Marinobacter_phage	7.1e-101	42.3
AXE92878.1\|2581827_2582226_-	hypothetical protein	NA	NA	NA	NA
AXE92879.1\|2582226_2582757_-	hypothetical protein	C7BGG0	Burkholderia_phage	7.0e-27	46.4
AXE92880.1\|2582868_2583102_-	hypothetical protein	NA	NA	NA	NA
AXE92881.1\|2583219_2583723_+	XRE family transcriptional regulator	NA	NA	NA	NA
AXE92882.1\|2583676_2584168_+	hypothetical protein	NA	NA	NA	NA
AXE92883.1\|2584314_2584548_+	hypothetical protein	NA	NA	NA	NA
AXE92884.1\|2584557_2584761_+	hypothetical protein	NA	NA	NA	NA
AXE92885.1\|2584767_2585124_+	beta-hexosaminidase	NA	NA	NA	NA
AXE92886.1\|2585120_2585366_+	hypothetical protein	NA	NA	NA	NA
AXE92887.1\|2585355_2585670_+	hypothetical protein	NA	NA	NA	NA
AXE92888.1\|2585662_2586946_+	transcriptional regulator	NA	NA	NA	NA
AXE92889.1\|2586942_2587395_+	hypothetical protein	NA	NA	NA	NA
AXE92890.1\|2587421_2587688_+	Pyocin activator protein PrtN	I6NSR8	Burkholderia_phage	2.6e-22	61.0
AXE92891.1\|2587666_2588761_-\|integrase	site-specific integrase	I6NSG1	Burkholderia_phage	6.6e-96	46.0
AXE92892.1\|2588925_2589393_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
2588938:2588968	attR	NA	NA	NA	NA
AXE94307.1\|2589530_2590211_+	cysteine dioxygenase	NA	NA	NA	NA
AXE92893.1\|2590262_2592881_-	mechanosensitive ion channel protein MscS	NA	NA	NA	NA
AXE92894.1\|2593051_2593699_-	3-beta hydroxysteroid dehydrogenase	NA	NA	NA	NA
AXE92895.1\|2593839_2594295_-	transcriptional regulator	NA	NA	NA	NA
AXE94308.1\|2594389_2594866_-	hypothetical protein	NA	NA	NA	NA
AXE92896.1\|2595129_2595711_+\|protease	protease	NA	NA	NA	NA
AXE92897.1\|2595912_2596239_+	hypothetical protein	NA	NA	NA	NA
AXE92898.1\|2596239_2597997_-	histidine kinase	W8CYF6	Bacillus_phage	5.0e-13	22.7
AXE92899.1\|2598405_2599608_+	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	2.5e-40	34.0
AXE92900.1\|2599691_2600039_-	hypothetical protein	A0A2H4J2R0	uncultured_Caudovirales_phage	7.5e-22	46.1
AXE92901.1\|2600347_2600728_+	fluoride efflux transporter CrcB	A0A2H4J148	uncultured_Caudovirales_phage	5.5e-26	53.8
AXE92902.1\|2600748_2602758_-	protein-L-isoaspartate O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.7e-23	48.1
AXE92903.1\|2602789_2604100_-	FAD-binding oxidoreductase	NA	NA	NA	NA
AXE94309.1\|2604138_2605569_-	homospermidine synthase	B2ZXX8	Ralstonia_phage	7.3e-103	41.1

DBSCAN-SWA_3

2833961 : 2867585

Bacillus_phage(28.57%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXE93072.1\|2833961_2835092_-\|transposase	IS481 family transposase	NA	NA	NA	NA
AXE93073.1\|2835209_2836340_-\|transposase	IS481 family transposase	NA	NA	NA	NA
AXE93074.1\|2836553_2838230_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	4.8e-13	35.7
AXE93075.1\|2838742_2839969_+	MFS transporter	NA	NA	NA	NA
AXE93076.1\|2840325_2842230_+	propionate--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	1.7e-54	31.1
AXE93077.1\|2842268_2843096_-	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
AXE93078.1\|2843092_2845444_-	DNA helicase II	S5M596	Bacillus_phage	9.9e-73	30.8
AXE94328.1\|2845624_2846731_-\|transposase	transposase	NA	NA	NA	NA
AXE93079.1\|2846978_2847389_-	hypothetical protein	NA	NA	NA	NA
AXE94329.1\|2847661_2847889_+	sulfurtransferase TusA family protein	NA	NA	NA	NA
AXE93080.1\|2848017_2848899_-	UTP--glucose-1-phosphate uridylyltransferase	A0A127AW70	Bacillus_phage	1.7e-70	48.1
AXE93081.1\|2848969_2851849_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	7.9e-149	40.1
AXE93082.1\|2852188_2853319_+\|transposase	IS481 family transposase	NA	NA	NA	NA
AXE93083.1\|2853506_2854547_-	oxidoreductase	NA	NA	NA	NA
AXE93084.1\|2854546_2855563_-	inositol 2-dehydrogenase	NA	NA	NA	NA
AXE93085.1\|2855555_2856437_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
AXE93086.1\|2856715_2857762_+	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
AXE93087.1\|2857908_2859066_+	ATPase	NA	NA	NA	NA
AXE93088.1\|2859079_2859907_+	sugar ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.9e-11	27.0
AXE93089.1\|2859972_2862012_+	5-dehydro-2-deoxygluconokinase	NA	NA	NA	NA
AXE93090.1\|2862008_2863976_+	3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing)	NA	NA	NA	NA
AXE93091.1\|2863986_2864913_+	myo-inosose-2 dehydratase	NA	NA	NA	NA
AXE93092.1\|2864909_2865710_+	5-deoxy-glucuronate isomerase	NA	NA	NA	NA
AXE94330.1\|2866071_2867178_+\|transposase	transposase	NA	NA	NA	NA
AXE93093.1\|2867282_2867585_+\|transposase	transposase	A9YX41	Burkholderia_phage	3.0e-27	65.3

DBSCAN-SWA_4

3225163 : 3237484

Methanothermobacter_phage(12.5%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXE93370.1\|3225163_3226378_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	1.4e-41	33.2
AXE93371.1\|3226449_3227469_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
AXE93372.1\|3227481_3227928_+	dUTP diphosphatase	Q2NP83	Xanthomonas_phage	1.1e-46	62.3
AXE93373.1\|3228025_3230323_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	4.7e-168	41.3
AXE93374.1\|3230319_3230634_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	5.8e-13	44.6
AXE93375.1\|3231183_3231390_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	2.4e-23	81.8
AXE93376.1\|3231591_3232848_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.4e-12	66.7
AXE93377.1\|3233182_3233752_+	pseudouridine synthase	NA	NA	NA	NA
AXE93378.1\|3234221_3234428_+	hypothetical protein	NA	NA	NA	NA
AXE93379.1\|3234573_3235077_+	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	1.9e-13	41.2
AXE93380.1\|3235378_3237484_+	elongation factor G	E4ZFJ7	Streptococcus_phage	3.8e-60	26.8

DBSCAN-SWA_5

3909663 : 3940114

Burkholderia_phage(94.74%)

terminase,head,portal,tail,integrase,capsid,plate

attL 3902898:3902938|attR 3940173:3940213

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3902898:3902938	attL	NA	NA	NA	NA
AXE93953.1\|3909663_3910722_-\|portal	phage portal protein	E5FFI9	Burkholderia_phage	1.4e-188	94.8
AXE93954.1\|3910721_3912497_-\|terminase	terminase	E5FFI8	Burkholderia_phage	0.0e+00	95.3
AXE93955.1\|3912647_3913691_+	hypothetical protein	E5FFI7	Burkholderia_phage	2.2e-125	72.6
AXE93956.1\|3913732_3914752_+\|capsid	phage major capsid protein, P2 family	E5FFI6	Burkholderia_phage	7.3e-174	90.5
AXE93957.1\|3914767_3915454_+\|terminase	terminase	E5FFI5	Burkholderia_phage	3.1e-104	88.6
AXE93958.1\|3915555_3916047_+\|head	phage head protein	E5FFI4	Burkholderia_phage	1.9e-74	90.2
AXE93959.1\|3916046_3916295_+	hypothetical protein	NA	NA	NA	NA
AXE93960.1\|3916294_3916501_+\|tail	phage tail protein	E5FFI3	Burkholderia_phage	1.7e-29	91.2
AXE93961.1\|3916515_3916857_+	hypothetical protein	E5FFI2	Burkholderia_phage	3.8e-50	97.3
AXE93962.1\|3916860_3917127_+	hypothetical protein	E5FFI1	Burkholderia_phage	2.9e-37	93.2
AXE93963.1\|3917123_3917930_+	peptidoglycan-binding protein	E5FFI0	Burkholderia_phage	1.1e-132	89.9
AXE93964.1\|3917926_3918379_+	hypothetical protein	E5FFH9	Burkholderia_phage	6.3e-53	78.7
AXE93965.1\|3918495_3918948_+\|tail	phage tail protein	E5FFH7	Burkholderia_phage	1.5e-75	95.3
AXE93966.1\|3918935_3919394_+	phage virion morphogenesis protein	E5FFH6	Burkholderia_phage	1.7e-74	94.7
AXE93967.1\|3919478_3920114_+\|plate	phage baseplate assembly protein V	E5FFH5	Burkholderia_phage	1.1e-79	78.1
AXE93968.1\|3920110_3920473_+\|plate	baseplate assembly protein	E5FFH4	Burkholderia_phage	7.1e-55	91.7
AXE93969.1\|3920469_3921384_+\|plate	baseplate assembly protein	E5FFH3	Burkholderia_phage	1.4e-136	83.8
AXE93970.1\|3921376_3921919_+\|tail	phage tail protein I	E5FFH2	Burkholderia_phage	2.3e-89	90.6
AXE93971.1\|3921922_3923491_+\|tail	phage tail protein	E5FFH1	Burkholderia_phage	9.6e-165	65.2
AXE93972.1\|3923502_3924372_+\|tail	phage tail protein	E5E3Q6	Burkholderia_phage	1.9e-106	73.3
AXE93973.1\|3924433_3925606_+\|tail	phage tail protein	E5FFG9	Burkholderia_phage	4.1e-197	88.5
AXE93974.1\|3925623_3926133_+\|tail	phage major tail tube protein	E5FFG8	Burkholderia_phage	4.0e-80	84.0
AXE93975.1\|3926207_3926492_+\|tail	phage tail assembly protein	E5FFG7	Burkholderia_phage	1.6e-41	95.7
AXE93976.1\|3926524_3926644_+\|tail	GpE family phage tail protein	E5FFG6	Burkholderia_phage	4.4e-14	94.9
AXE93977.1\|3926640_3929247_+\|tail	phage tail tape measure protein	E5FFG5	Burkholderia_phage	0.0e+00	77.9
AXE93978.1\|3929261_3929687_+	oxidoreductase	E5FFG4	Burkholderia_phage	3.7e-63	86.2
AXE93979.1\|3929683_3930724_+	late control protein	E5FFG3	Burkholderia_phage	7.2e-177	88.4
AXE93980.1\|3930761_3931232_-	hypothetical protein	E5FFG2	Burkholderia_phage	2.1e-43	61.4
AXE93981.1\|3931388_3931754_+	DUF2778 domain-containing protein	A0A1S6L3A5	Erwinia_phage	3.0e-29	52.1
AXE93982.1\|3932342_3933086_-	alpha/beta hydrolase	K4NZS4	Burkholderia_phage	5.9e-48	46.2
AXE93983.1\|3933137_3933581_-	transcriptional regulator	E5E3P4	Burkholderia_phage	1.0e-39	61.4
AXE94420.1\|3933655_3933892_+	hypothetical protein	K4NZX7	Burkholderia_phage	1.0e-22	73.3
AXE93984.1\|3933895_3934174_+	DNA-binding protein	E5E3P2	Burkholderia_phage	3.6e-35	78.0
AXE93985.1\|3934187_3934436_+	transcriptional regulator	K4PAZ0	Burkholderia_phage	7.0e-38	91.5
AXE93986.1\|3934520_3934739_+	hypothetical protein	NA	NA	NA	NA
AXE93987.1\|3934744_3934942_+	hypothetical protein	E5E3N9	Burkholderia_phage	1.1e-14	71.6
AXE93988.1\|3934986_3935187_+	hypothetical protein	K4NXL1	Burkholderia_phage	3.0e-07	54.0
AXE93989.1\|3935183_3935459_+	hypothetical protein	A4JWQ9	Burkholderia_virus	1.5e-20	63.8
AXE93990.1\|3935461_3938260_+	hypothetical protein	E5E3N5	Burkholderia_phage	0.0e+00	86.5
AXE93991.1\|3939034_3940114_+\|integrase	integrase	A0A1S5NNJ1	Burkholderia_phage	7.7e-174	84.2
3940173:3940213	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP024942

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP024942_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP024942_1

1167585-1167756

Orphan

Consensus_repeat	Method
CGAAAGGTGAGGGTTTTCGGGAGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of CP024942_1

>merge|CP024942|1|1167585-1167756|CRISPRCasFinder
TTAAAGGTGAGGGTTTGCGGGAGTGGCCCGTTTGGAACCATCGGTGCCCAGCCCAGCATGCCTTTGCGGCCTGCCACCAAGTTCGAAAGGTGAGGGTTTTCGGGAGCGGTCCGATGCGTGGCTTGCGTCGGACCCCAATCGCCGCGTGCCAAAGGTGAGGGTTTTCGGGAGC

>CP024942|1|1|1167585-1167756|CRISPRCasFinder
TTAAAGGTGAGGGTTTGCGGGAGT	GGCCCGTTTGGAACCATCGGTGCCCAGCCCAGCATGCCTTTGCGGCCTGCCACCAAGTT
CGAAAGGTGAGGGTTTTCGGGAGC	GGTCCGATGCGTGGCTTGCGTCGGACCCCAATCGCCGCGTG
CCAAAGGTGAGGGTTTTCGGGAGC

Protein	Signature genes	Signature genes Name	Protein_function
CP024942.1\|AXE95354.1\|1169900_1171094_+\|CoA-transferase	unknown	unknown	gnl\|CDD\|224717
CP024942.1\|AXE95343.1\|1156090_1156741_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377274
CP024942.1\|AXE95350.1\|1166314_1166863_+\|hypothetical-protein	unknown	unknown	unknown
CP024942.1\|AXE95347.1\|1160380_1161076_+\|DNA-alkylation-repair-protein	unknown	unknown	gnl\|CDD\|132881
CP024942.1\|AXE95346.1\|1159964_1160153_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240291
CP024942.1\|AXE95352.1\|1167881_1168640_-\|short-chain-dehydrogenase	unknown	unknown	gnl\|CDD\|180796
CP024942.1\|AXE95358.1\|1177590_1178340_+\|2-keto-4-pentenoate-hydratase	unknown	unknown	gnl\|CDD\|226480
CP024942.1\|AXE95348.1\|1163147_1165538_+\|chemotaxis-protein-CheA	unknown	unknown	gnl\|CDD\|340393
CP024942.1\|AXE95356.1\|1173908_1174634_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
CP024942.1\|AXE95351.1\|1166883_1167249_+\|response-regulator	unknown	unknown	gnl\|CDD\|381110
CP024942.1\|AXE95345.1\|1158250_1158769_+\|hypothetical-protein	unknown	unknown	unknown
CP024942.1\|AXE96882.1\|1161097_1162870_-\|phospholipase	unknown	unknown	gnl\|CDD\|197270
CP024942.1\|AXE95357.1\|1174796_1176017_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|178031
CP024942.1\|AXE95349.1\|1165583_1166306_+\|chemotaxis-protein	unknown	unknown	gnl\|CDD\|214599
CP024942.1\|AXE95355.1\|1172123_1173455_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
CP024942.1\|AXE96883.1\|1171123_1172065_+\|hydroxymethylglutaryl-CoA-lyase	unknown	unknown	gnl\|CDD\|163676
CP024942.1\|AXE95359.1\|1178363_1181396_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
CP024942.1\|AXE95353.1\|1168844_1169795_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176113
CP024942.1\|AXE95344.1\|1157545_1158025_+\|DUF1348-domain-containing-protein	unknown	unknown	gnl\|CDD\|377770
CP024942.1\|AXE96884.1\|1176268_1177555_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877

Protein	Function_ID	Function_description	E-value
CP024942.1\|AXE95354.1\|1169900_1171094_+\|CoA-transferase	gnl\|CDD\|224717	COG1804, CaiB, Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion].	7.3511e-148
CP024942.1\|AXE95343.1\|1156090_1156741_-\|hypothetical-protein	gnl\|CDD\|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	9.92446e-49
CP024942.1\|AXE95347.1\|1160380_1161076_+\|DNA-alkylation-repair-protein	gnl\|CDD\|132881	cd07064, AlkD_like_1, A new structural DNA glycosylase containing HEAT-like repeats. This domain represents a new and uncharacterized structural superfamily of DNA glycosylases that form an alpha-alpha superhelix fold that are not belong to the identified five structural DNA glycosylase superfamilies (UDG, AAG/MNPG, MutM/Fpg and helix-hairpin-helix). DNA glycosylases removing alkylated base residues have been identified in all organisms investigated and may be universally present in nature. DNA glycosylases catalyze the first step in Base Excision Repair (BER) pathway by cleaving damaged DNA bases within double strand DNA to produce an abasic site. The resulting abasic site is further processed by AP endonuclease, phosphodiesterase, DNA polymerases, and DNA ligase functions to restore the DNA to an undamaged state. All glycosylase examined to date utilize a similar strategy for binding DNA and base flipping despite their structural diversity. The known structures for members of this family, AlkC and AlkD from Bacillus cereus, are distant homologues and are composed of six variant HEAT (Huntington/Elongation/ A subunit/Target of rapamycin) repeats. HEAT motifs are ~45-amino acid sequences that form antiparallel alpha-helices, which are packed by a conserved hyrophobic interface and are tandemly repeated to form superhelical alpha-structures. AlkD and AlkC are specific for removal of 3-methyladenine (3mA) and 7-methylguanine (7mG) from the DNA by base excision repair. Homologues of AlkC and AlkD were also identified in other organisms.	6.94801e-83
CP024942.1\|AXE95346.1\|1159964_1160153_+\|hypothetical-protein	gnl\|CDD\|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	0.00279941
CP024942.1\|AXE95352.1\|1167881_1168640_-\|short-chain-dehydrogenase	gnl\|CDD\|180796	PRK07023, PRK07023, SDR family oxidoreductase.	6.35636e-131
CP024942.1\|AXE95358.1\|1177590_1178340_+\|2-keto-4-pentenoate-hydratase	gnl\|CDD\|226480	COG3971, COG3971, 2-keto-4-pentenoate hydratase [Secondary metabolites biosynthesis, transport, and catabolism].	8.62117e-11
CP024942.1\|AXE95348.1\|1163147_1165538_+\|chemotaxis-protein-CheA	gnl\|CDD\|340393	cd16916, HATPase_CheA-like, Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases. This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.	2.3013e-45
CP024942.1\|AXE95356.1\|1173908_1174634_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.53136e-47
CP024942.1\|AXE95351.1\|1166883_1167249_+\|response-regulator	gnl\|CDD\|381110	cd17562, REC_CheY4-like, phosphoacceptor receiver (REC) domain of chemotaxis response regulator CheY4 and similar CheY family proteins. CheY family chemotaxis response regulators (RRs) comprise about 17% of bacterial RRs and almost half of all RRs in archaea. This subfamily contains Vibrio cholerae CheY4 and similar CheY family RRs. CheY proteins control bacterial motility and participate in signaling phosphorelays and in protein-protein interactions. CheY RRs contain only the REC domain with no output/effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.59271e-40
CP024942.1\|AXE96882.1\|1161097_1162870_-\|phospholipase	gnl\|CDD\|197270	cd09173, PLDc_Nuc_like_unchar1_2, Putative catalytic domain, repeat 2, of uncharacterized hypothetical proteins similar to Nuc, an endonuclease from Salmonella typhimurium. Putative catalytic domain, repeat 2, of uncharacterized hypothetical proteins, which show high sequence homology to the endonuclease from Salmonella typhimurium and vertebrate phospholipase D6. Nuc and PLD6 belong to the phospholipase D (PLD) superfamily. They contain a short conserved sequence motif, the HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue), which characterizes the PLD superfamily and is essential for catalysis. Nuc and PLD6 utilize a two-step mechanism to cleave phosphodiester bonds: Upon substrate binding, the bond is first attacked by a histidine residue from one HKD motif to form a covalent phosphohistidine intermediate, which is then hydrolyzed by water with the aid of a second histidine residue from the other HKD motif in the opposite subunit. However, proteins in this subfamily have two HKD motifs in a single polypeptide chain.	4.54244e-45
CP024942.1\|AXE95357.1\|1174796_1176017_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|178031	PLN02409, PLN02409, serine--glyoxylate aminotransaminase.	1.43804e-151
CP024942.1\|AXE95349.1\|1165583_1166306_+\|chemotaxis-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	4.00029e-12
CP024942.1\|AXE95355.1\|1172123_1173455_+\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.22226e-88
CP024942.1\|AXE96883.1\|1171123_1172065_+\|hydroxymethylglutaryl-CoA-lyase	gnl\|CDD\|163676	cd07938, DRE_TIM_HMGL, 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain. 3-hydroxy-3-methylglutaryl-CoA lyase (HMGL) catalyzes the cleavage of HMG-CoA to acetyl-CoA and acetoacetate, one of the terminal steps in ketone body generation and leucine degradation, and is a key enzyme in the pathway that supplies metabolic fuel to extrahepatic tissues. Mutations in HMGL cause a human autosomal recessive disorder called primary metabolic aciduria that affects ketogenesis and leucine catabolism and can be fatal due to an inability to tolerate hypoglycemia. HMGL has a TIM barrel domain with a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. The cleavage of HMG-CoA requires the presence of a divalent cation like Mg2+ or Mn2+, and the reaction is thought to involve general acid/base catalysis. This family belongs to the DRE-TIM metallolyase superfamily. DRE-TIM metallolyases include 2-isopropylmalate synthase (IPMS), alpha-isopropylmalate synthase (LeuA), 3-hydroxy-3-methylglutaryl-CoA lyase, homocitrate synthase, citramalate synthase, 4-hydroxy-2-oxovalerate aldolase, re-citrate synthase, transcarboxylase 5S, pyruvate carboxylase, AksA, and FrbC. These members all share a conserved triose-phosphate isomerase (TIM) barrel domain consisting of a core beta(8)-alpha(8) motif with the eight parallel beta strands forming an enclosed barrel surrounded by eight alpha helices. The domain has a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. In addition, the catalytic site includes three invariant residues - an aspartate (D), an arginine (R), and a glutamate (E) - which is the basis for the domain name "DRE-TIM".	3.17059e-156
CP024942.1\|AXE95359.1\|1178363_1181396_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	8.22043e-76
CP024942.1\|AXE95353.1\|1168844_1169795_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176113	cd08421, PBP2_LTTR_like_1, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.74474e-80
CP024942.1\|AXE95344.1\|1157545_1158025_+\|DUF1348-domain-containing-protein	gnl\|CDD\|377770	pfam07080, DUF1348, Protein of unknown function (DUF1348). This family consists of several highly conserved hypothetical proteins of around 150 residues in length. The function of this family is unknown.	1.79151e-99
CP024942.1\|AXE96884.1\|1176268_1177555_+\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.82515e-93

>CP024942.1|AXE95351.1|1166883_1167249_+|response-regulator
MSKILVVDDSSTVRDEVAGFLKKNGLDADTAVDGKDGLAKLKASPGIKLVISDVNMPNMDGLTMVEKIRGELANKTVNVIMLTTESSPAMKERGKAAGVKGWIVKPFKGDAVLETFRKLAS
>CP024942.1|AXE95350.1|1166314_1166863_+|hypothetical-protein
MITAQARDSFERIFRKAAQARLPIEPGDTCEIAPVGAGDATRTDAMKGAQVVVLTISSIVFRLLLILHFDENDATRGYYLKDDVERPFQEVFLEICNLCCGAMNQELLRYFPDLGMSTPYVLSAHCLPYLRELNPDFVSAYSVTLNGSMQLAATICVCADAPVDFVADTSAMEETSGELELF
>CP024942.1|AXE95349.1|1165583_1166306_+|chemotaxis-protein
MIQQYVLATVAGSAVTALLALAAHKLQSARLIARLRAEAQASADTLKAEQSDRAEAIREPEQAAQHLEALAAQLRDELAQQSASADELRAALKAATDDKDQWAGQAQRIAGEAARLKHLGATFERWHEQMISLMTQNHDMHAKNQELSSIVRHVVIVSLNASIEAARAGPAGRGFAVVASEVRALAARSEELSKSYRDSLHRNDLTITSTFQDIQAGGKMIAASLASVESLANRFSSTLH
>CP024942.1|AXE95348.1|1163147_1165538_+|chemotaxis-protein-CheA
MTIRHRITLLVLLMFVALSAIGAYAVYQTRGSAAEVRKVTEGVVPSALASADLVSQVKDVQLATMTLVYAPDGDVVAQARDELSKKRVSLQQALALQARDAASHAQKGLVDQANDSLRNYFSAIAETAKMKAAGKNELAQAYLFANVAQYRDELEGIVETLRVEKNREKDEAITALNATLATTTTAIAIVTGIAIILLTLIGSLLYRQITCPLSRMQAMMSEIASSQDFTRRVPVGRLDEIGHSIVAFNGMIEKIRESSAQLKQKTADIQAMLQNMQQGILTVIDGAVIHAEYSAYLEDIFETKEIAGRGLMDLAFSETDIGLDALSRIDAAVHACLGEDCINFTFNQHLLVGEISKRMPDGRVKILDLSWSAITDENDVIVRLMLCVRDVTELRKLAAEASEQRRRLDMIGEILAVSEEKFHHFIESSAGFISENERIIRKHSEADHAAIAELFRNMHTIKGNARIYNLQHLTNVVHETEQSYHELRQPDADRPWDQEHLMRELTRVREAIESYARINEQSLGRKGKTGVNDAGHAGRYVMVEKEHIQRTLGMLDRTDANELQELQSMRDAMRKTLLALGSESVRDALSGVLDSLPSLASELGKPAPVVHIDDNGYRLRGAAGRTLNDVFMHLLRNSMDHGIETAETRSAQGKTPAGTIGIDVGVDRGALQITLSDDGRGLALERIRGIALERGWIRADEPLGDEAIAEFIFRPGFSTAETITEVSGRGVGMDAVRDFLERENGRIELRFTDDRKGAAFRQFQTIVCLPDSVAVDTLGADARGAASELRLGAIAG
>CP024942.1|AXE96882.1|1161097_1162870_-|phospholipase
MSVSVRSYLSPTLVLLAFDWPEGGTREDFLGFAIKRSPGFFAADGQEREASSWLPNRLTFQGAVPDTQKDAPSNEAPIQKFMWWDARIDEPDRETSFTYLVYPFVGTPDAPQLLDTQKGECRLTLPAHIESKVGTWFNRAVVSSQAFARKVAALHLAPHAAPTTDQALRLRTWLANDLQDVFDLTLAHARRAASAVYHLTDPLWAIPAFEAFGKQQGKASLAIVYDSHEVARKGKPPAPSPNQPAVDQLADLATFAPRDKTHIMHDKFVAVDDGNGEATPARVLTGSANFTTEGITEQANVLHLFDSPQLAALYSDRAKSLAANPSIAATAKLAPGWSDSIEIGTAKVRVCFSPEPKDSRLQIDTIVDAISKAKHSVLFCLFMPTDAPLRDACFAAGDKGRMMFGLVNHISAQSAEAAEKAQQNGQIVTSTALANMELYHRGRDKRDVIDAEYFSPATVPAGFEPELRLFPGESAPGYAPVIIHHKFLVIDAEGANPVVYTGSANMSNNSEHFNDENLLEIRDRRLAGTYLAEFLRLYEHYRARALAIREKNSGTHQRLMLAPNGSWAKKYFVADSPEAKARVALAHGAD
>CP024942.1|AXE95347.1|1160380_1161076_+|DNA-alkylation-repair-protein
MTPHAFGKEIKAALAPHADAQRSLAMRACMRNQFAFIGVPAPLRRQAVSPVFKRLPADNAGHLLACANVLWSMPQREYQYVATDLLARKWQALGIADIAHLLAIAQRNAWWDSIDPLAGVVGDVLKAARAQTPQAQAAMVAALEHEFLWVRRIAMLHQLGWREHTDEARLFGYARSLASESDFFIRKAIGWALRDYARHAPEAVSGFLSASRDLISPLTVREASKHLPSIR
>CP024942.1|AXE95346.1|1159964_1160153_+|hypothetical-protein
MKKLLAIAALAVLSATLSGCWWGPPPGGGGGGPGGGGPGGGRGDGPHGAIVIPDRVGNVAQG
>CP024942.1|AXE95345.1|1158250_1158769_+|hypothetical-protein
MHFRQIRKHIRRTALALVASVAGASAAHAGNWCEGGVWVDAMIGSYHIKPDAGTDFEPFNPGLGVECWLNNQWALTGGGFRNSLRRPSYYGGGVWAPEFAHWGIVRIAAMGGIISGYNYGDWGLGRDHTVGPVLAPLVMVEYKRVGANLIVIPPIPSDNLPFTIGFQLKVKF
>CP024942.1|AXE95344.1|1157545_1158025_+|DUF1348-domain-containing-protein
MADPIDTRPPLPPFTRETAIQKVRAAEDGWNTRDPERVSLAYTPDSVWRNRAEFTHGRAEIVGLLRRKWAKELDYRLIKELWAFTDNRIAVRFAYEWHDDSNNWFRSYGNENWEFDGHGLMARRHASINDLPIREADRLYHWPLGRRPDDHPGLTDLGL
>CP024942.1|AXE95343.1|1156090_1156741_-|hypothetical-protein
MSLLILRATLVRALLGAALLTAMACTPVQVLTHSVSQNETRVPAGRYDLDHDHCSITFDVDHFKYSRFTMRFDRKQGQLDWNEGGLQKSTAAITIDAASIDTNVPLLDKMVKSTSMLDVARYPEIRFVSTRFERTGESRGTLTGDLTIHGVAQPVTLDVTFNGFARDPLTKKDTLGFSADGRFSRAKFGLSTWYPAVGDDIHVRIQAEFGRAPAGG
>CP024942.1|AXE95352.1|1167881_1168640_-|short-chain-dehydrogenase
MTASFPIRAIVTGHTRGLGAALAEQLLARDVTVLGLSRSRHAALKARFPAQLEEIELELADPVRVAQWVATDALRAFVSGAQSILLINNAGMVQPIGPLEGQDAAVIASAVSLNVATPLILASALAAASVDANDRRIVHISSGAARNAYAGWSIYCATKAALDHHARAVALDRNRALRICSLAPGVIDTNMQAQIRDSGTEQFPMREKFEDLKRNGQLSTPEQCAMQLLDYAFSDAFGQTPVADIRELAKQA
>CP024942.1|AXE95353.1|1168844_1169795_+|LysR-family-transcriptional-regulator
MVIKNLLRKLDLTTLQLFLAVYEEGTLTRAAEREAIAVSAASKRLLELEQAVGATLFKRNARGMTLTPAGETLLHHARRVMRDIENIGIELAGHASGVRGYVRMMANLSAIVEFLPEDLRAFQLQHERVKLDLEERPSGGVLEAVDDSLADLGICSGDADTRDLHVVHYRRDSLVLVTRDDHPLAARASVAFAETLDGDHVGLHAASSINARTHMAARQAGKPLRLRIHVPGFDAVCRMVQAGMGVGVLPLKVYQLMGRSLGLVGVPLEDDWSERSLVLVVRDVEALSPVSRLLFEHLRSIEASEATEAPPADAAS
>CP024942.1|AXE95354.1|1169900_1171094_+|CoA-transferase
MGGPLQGIRVVEIGTLIAAPFAARLMAEFGADVIKIEAPQTGDPLRKWRKLHEGTSLWWYLQSRNKKSVCVNLKSADGVDIVKRLAADADVVIENLRPGALEKLGLGWDVLHAINPKLTMVRISGYGQSGPYRDRPGFGAIGEAMGGIRYTTGEMDGAPARVGVSLGDSLASLHGVIGALMSLLRVKTGQGEGQVVDVSLVESVFNLMESLVPEYDLLGHVRERSGGALPGIAPSNTYRTEDEGFVVIAGNSDPIFKRLMHVIGRADLADDPALAHNDGRAKQCAMLDQAITAWTSHHATDDVLAALERAEVPAGRIYSVADIVADPHYQARDMLLQAQLPGGASVKMPGIVPKLSDTPGEVRWSGPALGEHTGSVLSELGFASDDIERLRREGAVQ
>CP024942.1|AXE96883.1|1171123_1172065_+|hydroxymethylglutaryl-CoA-lyase
MSAPHFDKLIVQEVAPRDGLQIEPTWVDTADKIALINALSTAGFTRIEAGSFVSPKAIPALRDGEAVFQQIGRHPGVIYVALVPNLKGAERALASRADELNLVMSASQAHNRANMRMSCESSLIAFGDIVRHVQGSGVLLNATVATAFGCPFEGRIDEDRVIGIVDAYREMGIESVTLADTTGMANPRQVARLVARVLERLPASALTLHFHNTRGLGLANVLAAYDAGARRFDAALGGLGGCPFAPGASGNICTEDLVNLCDEMGIPTAIDLEKLLVLSRALPALLGHDVPGQLAKAGRNRDLHAVPEYVLQI
>CP024942.1|AXE95355.1|1172123_1173455_+|MFS-transporter
MSDLGAVASGNRERNADDAAAIIRKVAWRLMPLIMICYLFAFFDRINISFAKFQLQSDLGLSDTAYGLGASLFVIGYVLFEVPSNLFLYKVGARRWIARIMISWGLATAAMVFVSNEWQFYGLRFLIGAMEAGFAPGVLYYLTLWFPPSYRGRITSMLFLASAFSGLVGAPAAGLVIGHMNGVLGMPGWHWLFLLGGLPCVVLGFLVLKLLKDRIDEAGWLSPKEKSFLTAQIAQQSRHPETGHSLLGAIRTPGFLTLGLVYFLIQVGSYGLNFWAPHLIRVAGTHNPTVIGLLTAVPYVCGAICMVVVGRLSDASGERRKFVFGLLVMSAIGFFAAGFFDKQTALLIVALAVMGAGVVASIPAFWALPPKLVTGAGAAGGIALINTLGQLGGIVSPIMVGRVRDLTGSTTPALYVIGAMSLVCALIVLCGLPESLRQKDARH
>CP024942.1|AXE95356.1|1173908_1174634_-|GntR-family-transcriptional-regulator
MQNSDFDAGVRASQLMPKVERQRLHDTVVEHIRRFIVEGVLEPGKKLNERELCETLGISRTPLREALKVLAAEGLIEISPNRGASVSKMSEAELRETFELMSGLEAFSGELAAERMTAAELAEIKALHYAMLACRTQNDLPGYYSRNQAIHDKINEAARNSALRQTYIAVNRRLQALRFRSNFQIPKWDRAIHDHDEMLKALEARDGKKLSAILRQHLLDKRDAVLQVQSQEEVAGGGLKA
>CP024942.1|AXE95357.1|1174796_1176017_+|aminotransferase-class-V-fold-PLP-dependent-enzyme
MLKLDFHPAGRHFLQIPGPSPVPDRILRAMSYPTIDHRGPEFGELGLKVLEGIKKIFKTQQPVVIYPASGTGAWEAALSNTLSPGDHVLMFETGHFATLWKKMAESLGLKPEFLGLPGIEGWRRGVQPQMIEERLRADTQHAIKAVCVVHNETSTGVTSDIAAVRRAIDAAGHPALFLVDTISGLACADYRHDEWGVDVTVSGSQKGLMLPPGISFNAISPKALAAGKQAKLPRSFWDWTEIVEMNETGYWPYTPNTNLLYGLYEALDMILGEGLDNVFARHERLAEATRRAVRAWGLEIQCADPAVYSPVLTGVMMPDGVDADSVRKLIYERFDMSLGTGLGKMKGRMFRIGHLGDCNDLTLLATLAGCEMGLRLAGVSLKESGLPAAMEWLREPTHASGLKAAA
>CP024942.1|AXE96884.1|1176268_1177555_+|MFS-transporter
MKRFRVTSATSIVLVMLCIMYFITYLDRVNVSTAAAGFGKEFHLSHTEVGLVFSAFAYPYLLFQIIGGWVSDRFGARRTLLFCGAVWGVATLLTGFAGGLISLLAARVLLGFGEGATFPAATSAMARWVAKEKRGFAQGITHAASRIGNAVAPGLIVLVMATWGWRESFYICGIFSLLWVVVWAFTFTEHPKDHPRITSEELAVLPTPKPKAAGVPWGKLFRRMAPVTVVYFCYGWTLWLFLSWIPQYFLHSYHLDLKKSAIFASVVFLAGVIGDTLGGIVTDWIFTRTGSLKRARSWMVSVCMLFCLLSLIPLMFTHSVYLSMACLASGFFFAEMTIGPMWAIPMDIAPECSGTASGMMNTGSALAAIISPVVGGFLIDYSGSWELPFVGSMLLMAIGVVLAFRMQPESRFALGAADTTHATTSVGV
>CP024942.1|AXE95358.1|1177590_1178340_+|2-keto-4-pentenoate-hydratase
MATSLSRRLADARRDHTTLDALTPAQIPASADAAYAIQHEILNVFGARIGGWKIGAKSDSGPVQGAPLPHVDLHADGARLRRKAFAPLGLELEIAFRFGRRFDPSATPYGEAEVRAGIGSIGATIEIVASRYAAWPDVDKLAQLADLQNHGALIVGEFTPYREDFPFVAPSLRFSFDGHDVLEMAPANPAGDPRRLLTWLVNHATSRGIAVTPEMIVTTGSYTGMFFPRSAGTASGRIEGLAPVSVTLY
>CP024942.1|AXE95359.1|1178363_1181396_+|FAD-binding-oxidoreductase
MTNPTSALLVKPIHLVPSAARPSSPLAQHLRKSLRGDVLFDAASRGRYATDASIYQITPIGVVVPRDQDDLRIALDIARSEKVPLLARGAGTSQCGQTVGEALVIDTSKWLNSVVAFDAEARTVTVEPGVVLDHLNAWLKPHGLWFPVDVSTAAQCTIGGMAGNNSCGSRSIEYGNMVHNVEAIDAILADGGEARFASLREPPQSARLQQILAGVTQIAQRERDEIVARVPKVLRRVAGYNIDLFDCQNPRAYTDDGFANLAHLLVGSEGTLAFSRQLTLKLAPLPAHKTLGVVNFPTFWQAMDLTQHIVRLKPVAVELVDRTMIDLAMSNPAFRPVIEKALVGQPQAILLVEFAGEERDAQLASLKQLGELMADLGLPDSVVEMPDANEQKALWEVRKAGLNIMMSMKGDGKPVSFIEDCAVPPEHLAEYTSRLTEVFHRNGTEGTWYAHASVGTLHVRPILDMRRDGAVKMRAIAEEAAALVREYKGAFSGEHGDGLCRGEWVAWQYGPRLNQAFGEIKALFDPDNRFNPDKMVRPPKMDDARNFRFAPGYEARKIDTALDWSAWNVERDPLTGQETAPGSGNDLSGGLAKAVEMCNNNGHCRKFDAGTMCPSYRVTKDEQHVTRGRANTLRLAISGQLGEAGLASDDVKDTLDLCVSCKGCKRDCPTGIDMAKFKIEARAARVKRHGLRLRDRLVAFMPRYAATASRLPGLMALADNVPVLSAWFKRTVGFAPERRLPRFRKSFLSGMATTAAAAKPAKTGALKEVLLFVDTFNNNMEPENARAAQQVLEAAGYTVHFNTRQGERPVCCGRTFLAAGLVDEAKQEARRMLDLFGPFVERGVPIVGLEPSCLLSLRDEFLHYGFGEEAQRLSKQAFLFEEFLVREEKAGRLQLALKPLAKQQALVHGHCHQKAFDVFTPVQTVLKWIPGLTVSTVESSCCGMAGSFGYEAEHYASSQAMAELSLLPAVRKIDSNTVMVADGTSCRHQIHDGAGVDAIHVARVLAMALQ

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Crispr_ID: CP024942_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP024942_2

2115249-2115372

Orphan

Consensus_repeat	Method
AGTACGCGCCGGGCAGCCCCAAGCGTGCTGACGCCCCCTCGGGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP024942_2

>merge|CP024942|2|2115249-2115372|CRISPRCasFinder
AGTACGCGCCGGGCAGCCCCAAGCGTGCTGACGCCCCCTCGGGGGGCAGCGACCGCAGGGAGCATGGGGGTCGTTTCAAGTACGCGCCGGGCCGCCCCAAGCGTGCTGACGCCCCCTCGGGGGG

>CP024942|2|2|2115249-2115372|CRISPRCasFinder
AGTACGCGCCGGGCAGCCCCAAGCGTGCTGACGCCCCCTCGGGGGG	CAGCGACCGCAGGGAGCATGGGGGTCGTTTCA
AGTACGCGCCGGGCCGCCCCAAGCGTGCTGACGCCCCCTCGGGGGG

Protein	Signature genes	Signature genes Name	Protein_function
CP024942.1\|AXE96962.1\|2103987_2104062_-\|pyrroloquinoline-quinone-precursor-peptide-PqqA	unknown	unknown	gnl\|CDD\|178960
CP024942.1\|AXE96079.1\|2109889_2111935_+\|transketolase	unknown	unknown	gnl\|CDD\|183723
CP024942.1\|AXE96088.1\|2120514_2121465_-\|triphosphoribosyl-dephospho-CoA-synthase	unknown	unknown	gnl\|CDD\|376637
CP024942.1\|AXE96075.1\|2104529_2106047_+\|ribulose-bisphosphate-carboxylase-large-subunit	unknown	unknown	gnl\|CDD\|173977
CP024942.1\|AXE96085.1\|2118560_2119109_+\|dihydroneopterin-aldolase	unknown	unknown	gnl\|CDD\|214902
CP024942.1\|AXE96963.1\|2106763_2107717_+\|CbbX-protein	unknown	unknown	gnl\|CDD\|200217
CP024942.1\|AXE96076.1\|2106158_2106587_+\|ribulose-bisphosphate-carboxylase-small-subunit	unknown	unknown	gnl\|CDD\|177052
CP024942.1\|AXE96081.1\|2113031_2113763_+\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|235515
CP024942.1\|AXE96083.1\|2115402_2115981_-\|dihydromethanopterin-reductase	unknown	unknown	gnl\|CDD\|223967
CP024942.1\|AXE96089.1\|2121457_2122483_-\|RimK-family-alpha-L-glutamate-ligase	unknown	unknown	gnl\|CDD\|273261
CP024942.1\|AXE96078.1\|2108952_2109825_+\|phosphoribulokinase	unknown	unknown	gnl\|CDD\|237970
CP024942.1\|AXE96084.1\|2115977_2118095_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225822
CP024942.1\|AXE96091.1\|2124735_2125674_-\|methylenetetrahydromethanopterin-dehydrogenase	unknown	unknown	gnl\|CDD\|378132
CP024942.1\|AXE96080.1\|2111970_2113008_+\|fructose-bisphosphate-aldolase-class-II	unknown	unknown	gnl\|CDD\|181691
CP024942.1\|AXE96964.1\|2123488_2124694_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|225141
CP024942.1\|AXE96082.1\|2113853_2115236_-\|dihydropteroate-synthase	unknown	unknown	gnl\|CDD\|272997
CP024942.1\|AXE96087.1\|2119906_2120416_-\|formaldehyde-activating-enzyme	unknown	unknown	gnl\|CDD\|378034
CP024942.1\|AXE96086.1\|2119412_2119820_-\|hypothetical-protein	unknown	unknown	unknown
CP024942.1\|AXE96090.1\|2122479_2123514_-\|methenyltetrahydromethanopterin-cyclohydrolase	unknown	unknown	gnl\|CDD\|235020
CP024942.1\|AXE96077.1\|2107744_2108848_+\|class-1-fructose-bisphosphatase	unknown	unknown	gnl\|CDD\|236458

Protein	Function_ID	Function_description	E-value
CP024942.1\|AXE96962.1\|2103987_2104062_-\|pyrroloquinoline-quinone-precursor-peptide-PqqA	gnl\|CDD\|178960	PRK00284, pqqA, pyrroloquinoline quinone precursor peptide PqqA.	4.84194e-07
CP024942.1\|AXE96079.1\|2109889_2111935_+\|transketolase	gnl\|CDD\|183723	PRK12753, PRK12753, transketolase; Reviewed.	0
CP024942.1\|AXE96075.1\|2104529_2106047_+\|ribulose-bisphosphate-carboxylase-large-subunit	gnl\|CDD\|173977	cd08212, RuBisCO_large_I, Ribulose bisphosphate carboxylase large chain, Form I. Ribulose bisphosphate carboxylase (Rubisco) plays an important role in the Calvin reductive pentose phosphate pathway. It catalyzes the primary CO2 fixation step. Rubisco is activated by carbamylation of an active site lysine, stabilized by a divalent cation, which then catalyzes the proton abstraction from the substrate ribulose 1,5 bisphosphate (RuBP) and leads to the formation of two molecules of 3-phosphoglycerate. Members of the Rubisco family can be divided into 4 subgroups, Form I-IV , which differ in their taxonomic distribution and subunit composition. Form I is the most abundant class, present in plants, algae, and bacteria, and forms large complexes composed of 8 large and 8 small subunits.	0
CP024942.1\|AXE96085.1\|2118560_2119109_+\|dihydroneopterin-aldolase	gnl\|CDD\|214902	smart00905, FolB, Dihydroneopterin aldolase. Dihydroneopterin aldolase catalyses the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate. In the opportunistic pathogen Pneumocystis carinii, dihydroneopterin aldolase function is expressed as the N-terminal portion of the multifunctional folic acid synthesis protein (Fas). This region encompasses two domains, FasA and FasB, which are 27% amino acid identical. FasA and FasB also share significant amino acid sequence similarity with bacterial dihydroneopterin aldolases. This region consists of two tandem sequences each homologous to folB and which form tetramers.	2.96825e-31
CP024942.1\|AXE96963.1\|2106763_2107717_+\|CbbX-protein	gnl\|CDD\|200217	TIGR02880, Protein_CbxX_chromosomal, probable Rubsico expression protein CbbX. Proteins in this family are now designated CbbX. Some previously were CfxQ (carbon fixation Q). Its gene is often found immmediately downstream of the Rubisco large and small chain genes, and it is suggested to be necessary for Rubisco expression. CbbX has been shown to be necessary for photoautotrophic growth. This protein belongs to the larger family of pfam00004, ATPase family Associated with various cellular Activities. Within that larger family, members of this family are most closely related to the stage V sporulation protein K, or SpoVK, in endospore-forming bacteria such as Bacillus subtilis.	2.87867e-167
CP024942.1\|AXE96076.1\|2106158_2106587_+\|ribulose-bisphosphate-carboxylase-small-subunit	gnl\|CDD\|177052	CHL00130, rbcS, ribulose-1,5-bisphosphate carboxylase/oxygenase small subunit; Reviewed.	5.65565e-77
CP024942.1\|AXE96081.1\|2113031_2113763_+\|ribulose-phosphate-3-epimerase	gnl\|CDD\|235515	PRK05581, PRK05581, ribulose-phosphate 3-epimerase; Validated.	5.85283e-121
CP024942.1\|AXE96083.1\|2115402_2115981_-\|dihydromethanopterin-reductase	gnl\|CDD\|223967	COG1036, COG1036, Archaeal flavoproteins [Energy production and conversion].	6.06561e-38
CP024942.1\|AXE96089.1\|2121457_2122483_-\|RimK-family-alpha-L-glutamate-ligase	gnl\|CDD\|273261	TIGR00768, Tetrahydromethanopterin:alpha-L-glutamate_ligase, alpha-L-glutamate ligase, RimK family. This family, related to bacterial glutathione synthetases, contains at least three different alpha-L-glutamate ligases. One is RimK, as in E. coli, which adds additional Glu residues to the native Glu-Glu C-terminus of ribosomal protein S6, but not to Lys-Glu mutants. Most species with a member of this subfamily lack an S6 homolog ending in Glu-Glu, however. Members in Methanococcus jannaschii act instead as a tetrahydromethanopterin:alpha-l-glutamate ligase (MJ0620) and a gamma-F420-2:alpha-l-glutamate ligase (MJ1001).	1.32687e-48
CP024942.1\|AXE96078.1\|2108952_2109825_+\|phosphoribulokinase	gnl\|CDD\|237970	PRK15453, PRK15453, phosphoribulokinase; Provisional.	0
CP024942.1\|AXE96084.1\|2115977_2118095_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225822	COG3284, AcoR, Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription].	2.71033e-167
CP024942.1\|AXE96091.1\|2124735_2125674_-\|methylenetetrahydromethanopterin-dehydrogenase	gnl\|CDD\|378132	pfam09176, Mpt_N, Methylene-tetrahydromethanopterin dehydrogenase, N-terminal. Members of this family adopt a alpha-beta structure, with a core comprising three alpha/beta/alpha layers, in which each sheet contains four strands. They are predominantly found in prokaryotic methylene-tetrahydromethanopterin dehydrogenase, which catalyzes the dehydrogenation of methylene-tetrahydromethanopterin and the reversible dehydrogenation of methylene-H(4)F.	6.63012e-42
CP024942.1\|AXE96080.1\|2111970_2113008_+\|fructose-bisphosphate-aldolase-class-II	gnl\|CDD\|181691	PRK09196, PRK09196, fructose-bisphosphate aldolase class II.	0
CP024942.1\|AXE96964.1\|2123488_2124694_-\|ATP-binding-protein	gnl\|CDD\|225141	COG2232, COG2232, Predicted ATP-dependent carboligase related to biotin carboxylase [General function prediction only].	1.21324e-29
CP024942.1\|AXE96082.1\|2113853_2115236_-\|dihydropteroate-synthase	gnl\|CDD\|272997	TIGR00284, Uncharacterized_protein_MJ0107, dihydropteroate synthase-related protein. This protein has been found so far only in the Archaea, and in particular in those archaea that lack a bacterial-type dihydropteroate synthase. The central region of this protein shows considerable homology to the amino-terminal half of dihydropteroate synthases, while the carboxyl-terminal region shows homology to the small, uncharacterized protein slr0651 of Synechocystis PCC6803. [Unknown function, General].	5.78126e-46
CP024942.1\|AXE96087.1\|2119906_2120416_-\|formaldehyde-activating-enzyme	gnl\|CDD\|378034	pfam08714, Fae, Formaldehyde-activating enzyme (Fae). Formaldehyde-activating enzyme is an enzyme required for energy metabolism and formaldehyde detoxification. It catalyzes the condensation of formaldehyde and tetrahydromethanopterin to methylene tetrahydromethanopterin.	1.09916e-93
CP024942.1\|AXE96088.1\|2120514_2121465_-\|triphosphoribosyl-dephospho-CoA-synthase	gnl\|CDD\|376637	pfam01874, CitG, ATP:dephospho-CoA triphosphoribosyl transferase. The citG gene is found in a gene cluster with citrate lyase subunits. The function of the CitG protein was elucidated as ATP:dephospho-CoA triphosphoribosyl transferase.	1.1559e-63
CP024942.1\|AXE96090.1\|2122479_2123514_-\|methenyltetrahydromethanopterin-cyclohydrolase	gnl\|CDD\|235020	PRK02264, PRK02264, N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase; Provisional.	3.4263e-165
CP024942.1\|AXE96077.1\|2107744_2108848_+\|class-1-fructose-bisphosphatase	gnl\|CDD\|236458	PRK09293, PRK09293, class 1 fructose-bisphosphatase.	9.49529e-178

>CP024942.1|AXE96082.1|2113853_2115236_-|dihydropteroate-synthase
MDHIVFLTGRLAEKSLARVLDSMAPTPFSWEIREIGLQVAALMTADMIRRRVAAPLAAQRVIVPGRCRGDLDALSAHYGVPVERGPEEVKDLPQFFGREAKPMDLTHYETEIFAEIVDAPRLDLEGIAKRARDYAAQGADVIDIGCLPETPFPHLEDAVRLLKAEGYRVSVDSMRSEELLRGGRAGADYLMSLNLDTLWIADEVPSTPILVARDQREPASLDAAIDLLSARGRAFLADPILDPIPFGLAASIARYVGLRERYPDIAIMMGIGNVTELTEADTSGINAVLLGMAAELRVSAVLTTAVSLHARRAVREADVARRVMHAAREAQVLPKGINGDLATVHAKRPFPYSAAEIDDFAREVRDPNFRVQVSDDGIHVYNRDGHRVADDPFALYPQLNLDSDGGHAFYMGVQLARAEIAWRLGKRFDQDQPLDWGCAVDRPEQDLAAWCAPGETMKKR
>CP024942.1|AXE96081.1|2113031_2113763_+|ribulose-phosphate-3-epimerase
MRDFLIAPSLLSADFARLADEIRDVSAAGADWIHLDVMDNHYVPNLTVGPLVCAAIRPHTPVPIDVHLMTMPVDPLVLAFAEAGANTISFHPEASLHVHRTIELIKANGARAGLALNPATPLAVLDHVMEMLDVVVVMSVNPGFGGQAFIPETLEKLRSLRKSVDATMQRTGRPLLIEVDGGVKASNIAAIAAAGADVFVAGSAVFGADNYAQAIGGMRAELALGNVNLGVDLNDAAGFAVTH
>CP024942.1|AXE96080.1|2111970_2113008_+|fructose-bisphosphate-aldolase-class-II
MAFIALRQLLDHAAEHGYGVPAFNVNNMEQIHAIMQAAEATASPVILQASAGARKYAGEPYLRHLVLAALEAHPDIPLVLHQDHGASPAVCQQAIRSGFTSVMMDGSLLPDQKTPAGYDYNVDVSRRVVESAHAVGVSVEGELGCLGSLETGEAGEEDGVGAQGKLSRDDLLTDPHEAQIFVEATGVDALAIAIGTSHGAYKFSRQPTGDILAIDRIVEIHERIPNTHLVMHGSSSVPQEWLAIIREYGGEIPVTYGVPVEEIRRGIAHGVRKVNIDTDIRLAMSGAMRKSMANARSEFDPRAALKAATAAASAVCVERFEAFGCAGQAPRIKPLPLEAMARRYH
>CP024942.1|AXE96079.1|2109889_2111935_+|transketolase
MSAVAESVGAPATRLMADALRMLAIDAVEAAKSGHPGMPLGMAEIAVALWDRHLKHNPRDPAWPDRDRFVLSNGHGSMLLYGLLHLSGYDLPIDELKRFRQLHSKTPGHPEVGVTPGVETTTGPLGQGLANAVGMALAEALLAREFNRPGHAIVDHRTYVFTGDGCLMEGISHEAASLAGTLKLDKLTVLYDDNGISIDGHVQQWFADDTPARFAAYGWHVVRAVDGHDVDAVDRALQDARAAGKPTLICCKTVIGKGSPSKAGTHDVHGAPLGADEIGATRRALGWPHPPFVMPGEVRTLWDASERGAAAQAEWTQRFEAYRRHYPAEAAEFERRTQGALPAQWRDAVRAMVRDADCAAESIATRKASQQTIAVLARVLPEFLGGSADLTGSNLTNWKSAVDVHADDGGLQGGNYLHYGVREFGMSALMNGIALHRGHVPFGGTFLTFSDYSRNALRMASLMKTRAIFVFTHDSIGLGEDGPTHQAVEHAASLRLIPGLDIWRPCDTVETAQAWAQAVERGGPSCLLLSRQNLPFAARSGEQIDAVEQGGYVLRDWPDDSASQPRVVLIATGSEVALALDAVAPLAEAGIAARVVSMPSTSVFDRQPRAWRDAVLPPGVPRVAVEAGVTAFWRQYVGLEGGVVGIDSFGESAPAAALFTHFNLTTQAVVDEARRVAHGAP
>CP024942.1|AXE96078.1|2108952_2109825_+|phosphoribulokinase
MSLKHPIIAVTGSSGAGTTTVMKSFTHIFRREKINAQIVEGDAFHRYDRNGMREAMKEHERDGAPNFSHFGPEANLLEELETLFASYGESGTGKLRHYVHDEGESRLYKQDAGTFTPWEDVTPGTDLMFYEGLHGAAVTDRIDVARHADLLIGVVPIINLEWIQKLHRDQNMRGYSHEAVVDTILRRMPDYVNYICPQFSRTHVNFQRVPTVDTSNPFTAREIPAPDESFVVIRFARPKGIDFQYLLTMLHDSFMSRPNVIVVPGGKMGLAMQLIFTPMILQLIDRQARA
>CP024942.1|AXE96077.1|2107744_2108848_+|class-1-fructose-bisphosphatase
MQDGRTTLSKFLIDTLDRQPSPAGTTETAGLSALLIDVAAAIKSISAMLTKGALGGNYGSAQSINTHGEEQKKLDVATNEIFVQQCEWDGLLAAMASEEMETVYAIPPGYPRGDYLLAFDPLDGSSNIDINGVVGSIFSVLRNHGDKDAPVGEAAFLRPGCEQVAAGYAVYGPSTMLVLSVGNGTHGFTLERDIGNFVLTHSNIRIPEDTVEFAINASNERFWEPPVRRYVQECKDGRSGCRASDFNMRWIASMVAEVHRILMRGGVFMYPRDSKTPAMEGRLRLLYEANPMSFLIEQAGGLSITGRERILDVVPATLHGRVPVILGSKNEVERIGRYHGEYDRGEDKPFSSPLFNRRSLFLPDFTA
>CP024942.1|AXE96963.1|2106763_2107717_+|CbbX-protein
MDLAALYRDSGIGDVLAELDRDLVGLVPVKTRIREVAAHLLVERARDSLGLASGAPTLHMCFSGNPGTGKTTVALRMAEVLHRLGYIRRNHLVSVTRDDLVGQYIGHTAPKTRDVLKRAMGGVLFIDEAYYLYRPENERDYGQEAIEILLQTMENQRDDLVVILAGYASRMEIFFESNPGFRSRIAHHITFPDYEEAELLDIAERMLATMHYRFDADSRRAFAEYLALRIRQPNFANARSVRNALDRARLRQANRLFANAMKGGAPIDAAALTLIGAADVRASRVFDEPSAEAGSDAACASASASPPAPRAFQAPPG
>CP024942.1|AXE96076.1|2106158_2106587_+|ribulose-bisphosphate-carboxylase-small-subunit
MRITQGTFSFLPELTDEEIGLQIDYALSQGWACSVEYTDDPHPRNTYWEMWGLPMFDLRDAAGVLQEVRACRAAWPQHYIKVNAFDSERTFETMRLSFIVNRPDDEPGFRLTRQDGAGRVQRYGLSSYAGDRPAGERYGPAR
>CP024942.1|AXE96075.1|2104529_2106047_+|ribulose-bisphosphate-carboxylase-large-subunit
MNDFSQPVIETALDSQKPGNPGSSGKPRERYAAGVMKYREMGYWQPDYIPKDTDVIALFRITPQPGVEPEEAAAAVAGESSTATWTVVWTDRLTACDMYRAKAYRVDPVPSSSSGEPQYFAYIAYELDLFEEGSVANLTASIIGNVFGFKPLKALRLEDMRIPVAYLKTFQGPPTGIVVERERLDKYGRPLLGATVKPKLGLSGKNYGRVVYEGLRGGLDFLKDDENINSQAFMHWRDRFLFSMEAVNRAQAETGEVKGHYLNVTAGTMEDMYERAEFAKELGSCIVMIDLVIGWTAIQSMSRWARKNDMILHLHRAGHSTYTRQRNHGISFRVIAKWLRMAGVDHAHAGTAVGKLEGDPLSVQGYYNVCRDAHNEVDLSRGIFFDQPWAGLRKIMPVASGGIHAGQMHQLLDLFGDDAILQFGGGTIGHPAGIQAGAVANRVALESMVKARNEGRDIVNEGPEILEAAARWCTPLKQALDTWRDVSFNYASTDTPDFAATPSVA
>CP024942.1|AXE96962.1|2103987_2104062_-|pyrroloquinoline-quinone-precursor-peptide-PqqA
MQWTTPSYTDMRFGFEITMYIATR
>CP024942.1|AXE96083.1|2115402_2115981_-|dihydromethanopterin-reductase
MTQAPARHLNEFKPDARFAWCVTGSGHMIEESIALALELPRVDLFLSAAGEEVLPLYGWPLPKLRKHFRVLRDNSASGVPVGMLYHGVYHTVVIAPATSNTVAKCAFGISDTLPTNMFAQAGKQCIPGIVFACDTEPTVITQSPNEWVELRPRAIELDNVERLSRFEYTTLVRSLDELKAALGERLSTLDLV
>CP024942.1|AXE96084.1|2115977_2118095_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MSLLADSSLHVREVLNVVNHQLATRPTSEPVAQSWARCMNEFQLDPSRFVTPPILTEYELSERREALGDLIACSKLEMTTLYQQLADPELAVVLVDAGGVIVHQVSSVPFAEAVAPDGFRVGALWSEREAGTNGMGTCLAERDCIAVCQHEHFYPRYTSLTCSAAPIFDDSGEIAGVLDVTSRSKLLQQHSLVLVGMSRQMIENRLLDSRYRHANMIHFHSRPEFVGTLHGGKLAVADDSTVLAANRSALFQLGFRSLSELRGRRIEEAFNASLEDMIARSIRGSFHPVTVYSANATNRFFLVAQTPQNRAGRATRVALASPVPRAAPPEKRPPPARLDEIAHLEFGDPRMASQIQLAARVIQRKIPIVIRGQTGTGKEVFAQALHSISPHSAGPFVPVNCASLPENLIESELFGYRAGAFTGAQREGRRGKIVQANTGTLFLDEIGDMPLALQARLLRVIEEHEVTPLGAETTVKVNFQLISASHRNLLELVHGGQFREDLYYRLKGVELNLPPLCERLDKLALIHHLLENESGDDEPPELTAEAEHALLTYAWPGNIRQLRHVLQMAIALSDGQPIRCVDLPVEITQRAPSVGMPSAPNVAAAEFEAHLTDDADLSALNAIQLNERETVLSLLDEHRWNVSNVAKALGISRNTLYRKMRRLHIRLSHDGTPLDGAPPDGSPDGSPDDPSDGMPYNGSSPAAAA
>CP024942.1|AXE96085.1|2118560_2119109_+|dihydroneopterin-aldolase
MDRIDTVRLARFSGARADADASSPAARRDAPSAGASSGRMDIVFIENFVGQTIIGIDSSEQHVLQPIRMDLAIGVPSIRACTTDRIEDTINYAAVREALHALLAAHGVRLLEALAEAVARLLITDFGAHWVRVSLAKPAKFDDVAAVGVRIERQRSDLATTGSGLDAGLDSYASLGKGLIPN
>CP024942.1|AXE96086.1|2119412_2119820_-|hypothetical-protein
MSKRCRALVAGACLALAGPLAWGAGDAPGAAAPAGGFNYPTQGRVEYVLSCMDDNGHDFANVYKCSCVIDKMAAALPYDDFVDQSTFSKYATLGGEGGSEFRVDHAKAQTKKFRALQAEAYRSCGLASDKTAASK
>CP024942.1|AXE96087.1|2119906_2120416_-|formaldehyde-activating-enzyme
MAKINRVLIGESLVGDGNEVAHIDLLIGPRGSAAETAFCNALTNNKDGFTSLLAVVAPNLLTKPNTILFNKVTIKGAKQAVQMFGPAQHGVALAVADSVEDGTIPQDEADDLFLCVGVFIHWEADDDKKIQQFNYEATREAIKRAVNGEPNAAEVVAKKSTVAHPFAPN
>CP024942.1|AXE96088.1|2120514_2121465_-|triphosphoribosyl-dephospho-CoA-synthase
MPELLSAIAPERVRAAFLAACRLDVETPKPGNVSVQSEGHGMSAAQFLTSAEVAADALLAPGARVGSRILDAVTRTREAVGCNTNLGILLLVAPLAAALEETTLPLSADAWRAATERVLARLDLDDTRLAYRAIALANPGGLGDAPEQSVHAAPTVGLCDAMALAAGRDSIARQYANGFCDIFETGLAAWRDAHIASETTNQTPAQTATLNVFLAFLGGWPDSHIVRKHGVALAQSVTRAARERHTEWRRTLALSPQKPPTPSLDTWDAELKARGINPGTSADLTVATLFVAGCLEAHRDAPIEPRGPRTGTEHVS
>CP024942.1|AXE96089.1|2121457_2122483_-|RimK-family-alpha-L-glutamate-ligase
MTLALPDPNPVNAHANLRIAIMCDETGWHTGRLKKAFRARGAEARCIDLADCRIDTTWEPHGLVLPGFGRTLPDAVFVRGIAGGTFEQVTLRLGILHALRESGVPVYNDARAIERSVDKSMTSFLLHRNGVPTPATWAGESAAFAQRVLMREAAAGRQIVLKPLFGSQGHGLKRLGASRARGGALAPLPSLKPYQQVAYLQRYVDGGRSGFDWRVLVIGGRAVAAMRRIGGKGWIHNFAQGAECQPAELDLPLAQTAIRATHALGLDYAGVDLIPDPRDPARPLVLEVNGVAAWRGLQSVTPVDIAAALVDDLLDRKLADARRELAQGGDSAVATLPGRHA
>CP024942.1|AXE96090.1|2122479_2123514_-|methenyltetrahydromethanopterin-cyclohydrolase
MPSSSAIPDASSQPSGATAAPLSVNALSERLVARLVGDAARLGVALTRTDDGTVLADAGIAAPGSVAAGVLIARICMGGLGHVAVRTNFDAHPLWPSMIDVRTSSPVLACLGSQYAGWSLSATKEQTGGKKFFSLGSGPARALAVKEPLFAELGYKDAHERGVLVLEVDRLPPQVVIDKVLRDCGLAPDRLTLIMTPTHSVAGTVQVVARVVEVALHKTHVLGVPLDEVVEAGGSAPLPPPAPDGIQAMGRTNDAILYGGRVHLTVKHDAAAQQLAAELPASNSRDYGRPFADIFTSFNYDFYQIDPALFAPAEVWVSSLESGATYHGGALNSALLHEQWDGQP
>CP024942.1|AXE96964.1|2123488_2124694_-|ATP-binding-protein
MNSRPTLAHAPFVAVAGLSARMLAQSAARAGLRVVALDVFGDRDTREASELWFDIGGGPLTIDGAKLVDALARVARLPHMLGWIDGSGLEPFVAQLSRAPGLPRFIGNPLEASVAVREPQRFFPLLDALHIPHPEVSSTRPAVAQGWLLKRADGCGGTHIEPATASRDAPLPAQAYFQRRRNGRSLSALFIGARGGARLLGFAEQLTCTMGDLPFVHAGSIGPIDLPPRVAARVREAIEALCERTGLTGINSCDFLLDGDTFELLEINARPSSTMTLYETASPHAWPRGLLACHIDACRYGRLPPEPLAPASWRAGQQVLFAPHPFTVSQAFSDACLHDPACRDVPMPGTWMEAGQPVCTLLVRAASVSGVRQALERQRALVLERIETCHEPDYAFIQCHS
>CP024942.1|AXE96091.1|2124735_2125674_-|methylenetetrahydromethanopterin-dehydrogenase
MSDTTEKPAERPYILHMFTATPQMSPFDVNMAADAGYQVIVPYCSVDQGMIANLTQDAIFSRGPKGVSRTGIFIGGRDVMLAADMLDTARRAMVPPFEVSVFADPSGSYTTAAALVALVERHLSKAYGMELGGKRVLILGGTGAVGRVAAAMAASLGADVSIASHAEQARAVRVSDEINQRFGIVTKGISTATPDQLHAALGEAEIVLATAIAGVQVVSAADLAHAKHLLIAADVNAVPPEGIAGVNVMNDGKPIEGVPNADAIGIGALAIGNVKYQVEHRLFMRMRAGGKPVYLGFPQAFDEARAVAAGLE

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Crispr_ID: CP024942_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP024942_3

2690675-2690748

Orphan

Consensus_repeat	Method
AGTAAGCGCTGAAGCGCTAACTCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP024942_3

>merge|CP024942|3|2690675-2690748|CRISPRCasFinder
AGTAAGCGCTGAAGCGCTAACTCCTGTCGACTCGCTTTGCGTGGGGCCGAAGTAAGCGCTAAAGCGCTAACTCC

>CP024942|3|3|2690675-2690748|CRISPRCasFinder
AGTAAGCGCTGAAGCGCTAACTCC	TGTCGACTCGCTTTGCGTGGGGCCGA
AGTAAGCGCTAAAGCGCTAACTCC

Protein	Signature genes	Signature genes Name	Protein_function
CP024942.1\|AXE96539.1\|2700296_2701259_+\|ribokinase	unknown	unknown	gnl\|CDD\|238579
CP024942.1\|AXE96533.1\|2690766_2691771_+\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
CP024942.1\|AXE96529.1\|2683686_2685858_-\|TonB-dependent-siderophore-receptor	unknown	unknown	gnl\|CDD\|273805
CP024942.1\|AXE96530.1\|2686053_2688042_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225822
CP024942.1\|AXE96532.1\|2689624_2690608_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|223997
CP024942.1\|AXE96536.1\|2693909_2696336_-\|penicillin-acylase-family-protein	unknown	unknown	gnl\|CDD\|376618
CP024942.1\|AXE96535.1\|2692889_2693885_+\|lipoyl-synthase	unknown	unknown	gnl\|CDD\|237261
CP024942.1\|AXE96526.1\|2679262_2680306_-\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237562
CP024942.1\|AXE96524.1\|2676900_2677491_+\|flavin-reductase-family-protein	unknown	unknown	gnl\|CDD\|224766
CP024942.1\|AXE96537.1\|2696758_2697769_+\|deoxyribose-phosphate-aldolase	unknown	unknown	gnl\|CDD\|223351
CP024942.1\|AXE96538.1\|2697785_2700173_+\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143429
CP024942.1\|AXE96523.1\|2676156_2676891_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
CP024942.1\|AXE96527.1\|2680592_2681789_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|227940
CP024942.1\|AXE97008.1\|2703552_2705106_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
CP024942.1\|AXE96528.1\|2682311_2683529_-\|chromate-transporter	unknown	unknown	gnl\|CDD\|273350
CP024942.1\|AXE96525.1\|2677536_2679132_-\|gamma-glutamyltransferase-family-protein	unknown	unknown	gnl\|CDD\|223482
CP024942.1\|AXE96531.1\|2688492_2689575_+\|ATP-NAD-kinase	unknown	unknown	gnl\|CDD\|225740
CP024942.1\|AXE96540.1\|2701326_2702364_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
CP024942.1\|AXE96534.1\|2691774_2692887_+\|acetoin-dehydrogenase-dihydrolipoyllysine-residue-acetyltransferase-subunit	unknown	unknown	gnl\|CDD\|184875
CP024942.1\|AXE96541.1\|2702474_2703479_+\|autoinducer-2-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380656

Protein	Function_ID	Function_description	E-value
CP024942.1\|AXE96539.1\|2700296_2701259_+\|ribokinase	gnl\|CDD\|238579	cd01174, ribokinase, Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway. Ribokinase is dimeric in solution.	4.18917e-115
CP024942.1\|AXE96533.1\|2690766_2691771_+\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	7.25508e-177
CP024942.1\|AXE96529.1\|2683686_2685858_-\|TonB-dependent-siderophore-receptor	gnl\|CDD\|273805	TIGR01783, Ferrienterobactin_receptor, TonB-dependent siderophore receptor. This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	1.05114e-96
CP024942.1\|AXE96530.1\|2686053_2688042_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225822	COG3284, AcoR, Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription].	0
CP024942.1\|AXE96532.1\|2689624_2690608_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|223997	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion].	5.38731e-140
CP024942.1\|AXE96536.1\|2693909_2696336_-\|penicillin-acylase-family-protein	gnl\|CDD\|376618	pfam01804, Penicil_amidase, Penicillin amidase. Penicillin amidase or penicillin acylase EC:3.5.1.11 catalyzes the hydrolysis of benzylpenicillin to phenylacetic acid and 6-aminopenicillanic acid (6-APA) a key intermediate in the the synthesis of penicillins. Also in the family is cephalosporin acylase and aculeacin A acylase which are involved in the synthesis of related peptide antibiotics.	0
CP024942.1\|AXE96535.1\|2692889_2693885_+\|lipoyl-synthase	gnl\|CDD\|237261	PRK12928, PRK12928, lipoyl synthase; Provisional.	0
CP024942.1\|AXE96526.1\|2679262_2680306_-\|rod-shape-determining-protein	gnl\|CDD\|237562	PRK13927, PRK13927, rod shape-determining protein MreB; Provisional.	0
CP024942.1\|AXE96524.1\|2676900_2677491_+\|flavin-reductase-family-protein	gnl\|CDD\|224766	COG1853, COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only].	1.10817e-38
CP024942.1\|AXE96537.1\|2696758_2697769_+\|deoxyribose-phosphate-aldolase	gnl\|CDD\|223351	COG0274, DeoC, Deoxyribose-phosphate aldolase [Nucleotide transport and metabolism].	1.83606e-75
CP024942.1\|AXE96538.1\|2697785_2700173_+\|aldehyde-dehydrogenase	gnl\|CDD\|143429	cd07111, ALDH_F16, Aldehyde dehydrogenase family 16A1-like. Uncharacterized aldehyde dehydrogenase family 16 member A1 (ALDH16A1) and other related sequences are present in this CD. The active site cysteine and glutamate residues are not conserved in the human ALDH16A1 protein sequence.	0
CP024942.1\|AXE96523.1\|2676156_2676891_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	3.15979e-43
CP024942.1\|AXE96527.1\|2680592_2681789_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|227940	COG5653, COG5653, Protein involved in cellulose biosynthesis (CelD) [Cell envelope biogenesis, outer membrane].	1.71526e-13
CP024942.1\|AXE97008.1\|2703552_2705106_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
CP024942.1\|AXE96528.1\|2682311_2683529_-\|chromate-transporter	gnl\|CDD\|273350	TIGR00937, Chromate_transport_protein, chromate transporter, chromate ion transporter (CHR) family. Members of this family probably act as chromate transporters, and are found in Pseudomonas aeruginosa, Alcaligenes eutrophus, Vibrio cholerae, Bacillus subtilis, Ochrobactrum tritici, cyanobacteria and archaea. The protein reduces chromate accumulation and is essential for chromate resistance. [Transport and binding proteins, Anions].	5.55444e-78
CP024942.1\|AXE96525.1\|2677536_2679132_-\|gamma-glutamyltransferase-family-protein	gnl\|CDD\|223482	COG0405, Ggt, Gamma-glutamyltransferase [Amino acid transport and metabolism].	5.50109e-159
CP024942.1\|AXE96531.1\|2688492_2689575_+\|ATP-NAD-kinase	gnl\|CDD\|225740	COG3199, COG3199, Predicted inorganic polyphosphate/ATP-NAD kinase [General function prediction only].	5.38381e-26
CP024942.1\|AXE96540.1\|2701326_2702364_+\|sugar-ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	7.08594e-63
CP024942.1\|AXE96534.1\|2691774_2692887_+\|acetoin-dehydrogenase-dihydrolipoyllysine-residue-acetyltransferase-subunit	gnl\|CDD\|184875	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional.	0
CP024942.1\|AXE96541.1\|2702474_2703479_+\|autoinducer-2-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380656	cd20001, PBP1_LsrB_Quorum_Sensing-like, ligand-binding protein LsrB-like of ABC transporter periplasmic binding protein. Ligand-binding protein LsrB-like of a transport system, similar to periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs from other bacteria. The members of this group are homologous to a family of periplasmic pentose/hexose sugar-binding proteins that function as the primary receptors for chemotaxis and transporters of many sugar based solutes in bacteria and archaea and that are a member of the type 1 periplasmic binding protein superfamily. LsrB, which is part of the ABC transporter complex LsrABCD, binds a chemically distinct form of the AI-2 signal that lacks boron, in contrast to the Vibrio harveyi AI-2 signaling molecule that has an unusual furanosyl borate diester. Hence, many bacteria coordinate their gene expression according to the local density of their population by producing species specific AI-2. This process of quorum sensing allows LsrB to function as a periplasmic AI-2 binding protein in interspecies signaling.	6.65103e-136

>CP024942.1|AXE96532.1|2689624_2690608_+|ABC-transporter-substrate-binding-protein
MSVSSDLSKDELLKAYRMMRTIREFEERLHVEFATGEIPGFVHLYAGEEASAVGTMLHLNDADYVATTHRGHGHCIAKGVDVHGMMAEIYGRKTGVCHGKGGSMHIADLSKGMLGANGIVGAGGPLICGAALAAKYKKSGGVGVCFFGDGASNQGVIFESMNLASVWRLPAIFVAENNGYAEATSSTWSVATDNIADRASGFGMPGVIVDGFDFFAVHEALGEAIERARHGGGPTLVEVKFSRYFGHFEGDAQTYRAPGEVQKLRDEKDCLKRFEERVVRAEMLSADQLRGVDAEVKTLIDSAVTQAKAAPLPTAEDLLSDVYVSYP
>CP024942.1|AXE96531.1|2688492_2689575_+|ATP-NAD-kinase
MPSPVTVGVIANPASGRDIRRLTTYASVFPTAEKANMVVRLLAGLGVLGVDRVLTLRDRTGVAALLLRALDTHAAVAAQQRWPQVEFIEQPITDSVSDTHAGVTAMLQAGVELIAVLGGDGTHRAVAAHCGKVPLLTLSTGTNNAFPDLREATVAGLAGALVASGAVPAEVALMRNKRLVVRCVDGPNRGREEIALVDVCVSRQRFVGARAVSDPADIEALFLTFASPDGIGLSSIGGAWAPVERTASHGLHLRFARPGGVGAIGAIGVPIVAPIAPGRVERVFMRTCERFEVGVWMPLDTEHGTLAFDGEREIELERGDRYEIALDWDGPLTVDVERTLRYSASRQLVREVANVAAHHK
>CP024942.1|AXE96530.1|2686053_2688042_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MPYVSQTQHIDRVRGAIEGRLPAPADSARLVSSWQRSFEQYRLDPGAVIGPRVLTSAELREVQGRQEAFLRASGQCLTRLHDMIRVADYCVMLTDAHGVTIDYRIDRERRGDFKHAGLYIGSCWSEREEGTCGVANVLTDLAPITVHKTDHFRAAFTTLTCSAAPIFAPTGEMIGVLDASAVQSPDNRDSQRLVFQLVRQSAGLIEDGYFLNQTTQHWILFGHASRNFVEAQPEILIAFDECGNLVAANRKARECIPALNGPRHMDEIFDTSDVHLHDVARTDAIVGLRLRATGSTLYARIRAPLKRVSRGTAGVADGVAGSPHSASRKEPPIGALGRFLHSADPRIARNAAVALRIIGKRLPILILGETGVGKEVFAHALHDAGARRTRPFIAVNCGAIPESLIESELFGYVPGAFTGARSRGARGKIAQAHTGTLFLDEIGDMPLNLQTRLLRVLAEGEVVPLGGDAPVRVDLDVICATHRDLAGMVAEGSFREDLYYRLSGASLAMPPLRERADIRDVIEAVFDEEARMAAHVLTLDARLADRLAAFHWPGNIRQLRNVLRYACAVCDSSRVELRHVAPDIAALLEPDTASNLTLMHAKPLANALANSQDDPRDERARIVDALTRHQWRPNAAAQALGISRATLYRRIAKLGIVGPHRG
>CP024942.1|AXE96529.1|2683686_2685858_-|TonB-dependent-siderophore-receptor
MRFLRTSALPGRHGRHRRFHIGLRAALLMCTATAHAAMAATPDAGGDPPSNPQELPAVSVHASPAVEPTAGYRPLTSETSSGIERKISEIPQSVAVVSSSVMQDQQARSLDDALGNVSGITQTNTLGGTRDAFLKRGFGSNNDGSILVDGIRSPILHNYLATIDRVEVLKGPASLLYGIQEPGGVINMITRKPEDTLQGSVSATYTSHRGSGTSFDLTGPIGQPGQVAGGTLAFRLTGEYNTARYWRSFGRQRDALIAPSLSWHDANTSIDVSYQYVDYTTPFDRGTVLVNGHPDDALRYTRYEEAWAQSSGLQETLRAKLEHRFSDQWRMRATYGWSRDRYDQYLTRASAFNSRTGIMSRSSDANLGRNDADEIATIGAIGDLNLAGMRHEVYVGGEYERQRSFRGDTIRGKAVSGFDLFDPVYGRLAAGGTPSATQSDSLSKVHTYSLITQDTVHLTDRLIAVAGVRWENWQQLSGVGRPFVVADHSHGQVWLPQFGLVYKLTPALSAYANFSKSFVPNVATEVSEPLSPERGRIYEAGLKFDLKPGITGTLAVYQIDKSNVAVTNGDVTSTIGSARSRGVELDVAGQLTRHVSLIASYAYTNATDRDDGTRLANAARHTGSVFAVYDTMLPYLPGQWRFGGGARLVGRRAGDTANSFTLPGYVVADLFAAYETKLGKIPTRVQLNVKNVFDKTYYPSSNSNLIIAEGEARLVMLNTTFSF
>CP024942.1|AXE96528.1|2682311_2683529_-|chromate-transporter
MNLADTESTAAAPARTSPWALLFIFLRLGLTSFGGPAAHLGYFRDEFVKRRRWLDEHTFGDIVALCQFLPGPGSSQVGIAIGWLRGGLGGALAAWLGFTLPSVVLLVGFAYGFTHLTDATSLHLVHGLKLAAVAVVAQAVWSMGRTLCPDRARATFAIGAAAAVVMLGATYGQLASIVVAGVAGAAFLKTSTEVPGAPLGMPGTKAGAFVCLCAFVLLLFGLPALAASLRVHALDLFAAFYRVGSLVFGGGHVVLPLLQAVVVPRGWLSTNEFMAGYGAAQAVPGPLFSFAAFLGAASKGQPSGIGGALIATAAIFLPSFLLVGAALPLWGQLRAFASMRRAMAGINAAVVGILLAALYDPVWTSAVHGGADFVLVLIALLLLGWWRAPSWAVVLITTALAWWVA
>CP024942.1|AXE96527.1|2680592_2681789_+|GNAT-family-N-acetyltransferase
MQPAHAARTARRYEVIGDEAAFRALQHEWDVLWSRAHGHYYQSFSYCWLAWRHVSKPHGRRLKCIVCREGGQLVMIWPLETCRRALWTYLVPLGPEGGDYTSVLVRDGEAAPALIAGAWDTARRRCGADFIHLQYVRETLELYTLVSRERSVLFAEAHNAFAARLRGRGERNGWDDYCRTLGTLFGKRPGGFAKRLSREGKVAVRVVDPAEESETASIVEWMLNCKRSWSDRVGKRSAWLDSPEYECFLAKLIHSPDVPSMARLIVVTLNEAPVAAIIVSVGNPWASAIFAGYDPYYGRCCPGLVAVEACVKWAFDNGFDLDFGVGNERFKAYWSRGEASTAWTVRTVNSLWGLLAIRGWRLARYLGARVKGLREAGAASPEAARVFTRDGKRATRVS
>CP024942.1|AXE96526.1|2679262_2680306_-|rod-shape-determining-protein
MFGFLRGYFSNDLAIDLGTSNTLIYMRGKGIVLDEPSVVSIRQEGGPNGKKIILAVGKEAKQMLGKVPGNIEAIRPMKDGVIADFNITQQMIKRFIQMAHESRVFAPSPRIVICVPCGSTQVERRAIKEAAHSAGASQVYLIEEPMAAATGAGLPVSEATGSMVVDIGGGTTEVGVISLGGIVYKGSVRVGGDKFDDAIVNYIRRNYGMLIGEQTAESIKKQIGSAFPGSEVKEMEVKGRNMSEGIPRSFTVSSNEVLEALTDPLNQIVSAVKIALEQTPPELGADIAERGIMLAGGGALLRDLDRLLAEETGLPVFVAEAPLTCVVRGSGMALERIDKFGGAFSYE
>CP024942.1|AXE96525.1|2677536_2679132_-|gamma-glutamyltransferase-family-protein
MSDTQLARSNGGMVTSPHGLASEAGRDVLRAGGNAIEAAIAIGAALCVTYPHFTGLGGDAFWVIGDGDGMLRTLSGIGQAAAELPAQTTSPGAIPLRGAAAALTTAATVDTWAQAYEISKNAWGGEQSWSSLFDRALGHASEGFPVTPSQHFWQSLRADELRALPGFAATFAPTGVIPAIGERFAQPALARSLERIARFGAREFYNGELAERIARGLQQAGSPLSASDLARTRARDEAPLRVPYRGGELVSLRPPTQGVTTLQIMGTLARFDLGAIPEGSADYYHLLVEAVKCAFVDRDRFVSDPEFNDVPVDHMLSPATLDAHARSIDLRAARAWPHVFRPGDTVFIGATDRHGRSVSVLQTVYFDWGSGVVAGDTGILWHNRGASFSTHPAHHNAIEPGKRPFHTLNPGMYLQDGRPRLLFGTQGADGQPQTLAAVLTRLIDYGMDPLSALARPRFLLGKTFSDTRDALKLEEDAGADVFAALAARGHEVSAIAAQSPLAGHPGVIRIEPDGWASGAHDPRSDGRALGV
>CP024942.1|AXE96524.1|2676900_2677491_+|flavin-reductase-family-protein
MEIDFAAITEYQRYKLMASLIVPRPIALVTTLGADGTINAAPFSMFNMLGEEPPIVMISVNRVADGTLKDTAVNIVRTGEFVVHLADEAIAEKMHRCGERLPPHVSELAAVGLTPVPSTHVAPPRIAEAPVAFECTTWETLETASRQIFIGRVHRLHARDELIDTGTWRVRLQHYFPVGRFGASDYVTTRDRFTLG
>CP024942.1|AXE96523.1|2676156_2676891_+|GntR-family-transcriptional-regulator
MSAKAGAAAARKAPKDDADVDARIYQSIFDGVLNHRLTPGTKLPEPELCHLFGVGRAVVRRVLEKLAYDGIVVLRPNKGAVIAEPTPEETREIFEARRSVERMLVELAVQRASAKDIEALRQQLASEHEAMHRFDQPSWATLASGFHMQIATLAGNSILQNYLRELVSRCSLILGVYEPPGNAPCEHAEHAAIVACLEARDAAGAMAHMEAHLRHLEERIETSRMRGEKSLGQLLGIAGHATQT
>CP024942.1|AXE96533.1|2690766_2691771_+|alpha-ketoacid-dehydrogenase-subunit-beta
MARKITFSQAINEALSQEMARDETVIVMGEDNAGGAGSPGEQDAWGGVLGVTKGLFHKYPGRVLDTPLSEGGYIGAAVGAAACGMRPVAELMFIDFMGVCFDQIFNQAAKFRYMFGGKAVTPVVIRAMQGAGLRAAAQHSQMLTSLFTHIPGLKVVCPSTPYDAKGLLIQAIRDNDPVIFCEHKLLYGREGDVPEESYAIPFGEANVVRDGDDATIVTYGRMVHYATEAAQKLAKDGIEVDVIDLRTTSPLDEETILESAARTGRVVVVDEANPRCSIATDISALIAQRAFHSLKAPIEMVTAPHTPTPFAGVLEDMYIPSAQQIAEAVLKVRG
>CP024942.1|AXE96534.1|2691774_2692887_+|acetoin-dehydrogenase-dihydrolipoyllysine-residue-acetyltransferase-subunit
MPIHMITMPKWGLSMEQGQVNGWLKNVGDKVAKGDEILDVETDKISSGVECAFDGILRRQVAQEGDTLPIGALLAVVADAQTPDAEIDAAVEAFQRDFVPASAEAGESGPQPEKAQIGGRTVRYLKLGEGGTPAVLIHGFGGDLNNWLFNHADLAAHRTVWALDLPGHGESGKAVETGSADELADSVIAFLDDRGIDNAHLIGHSMGALVAMTVAAKAPQRVASLALIAGAGLGEEINGDYLAGFAEGSSRNALKPHLMKLFADPALVTRQLVEDIVKYKRLEGVNDTLRKIASEAFDGNVQRTRYRDRLAQLAPRTLVIWGADDQIIPAAHAQGLEGDIRVHVLEGKGHMVQMEAASEVNRLLDDFLGR
>CP024942.1|AXE96535.1|2692889_2693885_+|lipoyl-synthase
MSAALHGDSVTALGQHGKRSGEKLARIPVKIVPVSDGEVLPKPSWLHAKPMMSETVAGIAAVLREHRLHSVCEEAMCPNIGECFAQRTATFMVMGGICTRRCAFCDVAHGRPAPLDDEEPQRLAHAVAALGLRYVVVTSVDRDDLRDGGAAHFARCVALLRERMPGIRVEVLTPDFRGRVERALAALSQAWPDVFNHNLETVPSLYRAARAGADYRGSLQLLARVKEANASVLTKSGLMVGLGEADDELLDTMRDLRAHRVDILTLGQYLAPSRFHLPVRRYATPEQFAAWRGAGLKMGFREVVAGPLVRSSYHADRVADAASHALIREQA
>CP024942.1|AXE96536.1|2693909_2696336_-|penicillin-acylase-family-protein
MQPARKIIALIAYAGFTALTATAHAARAAEIPVETITLEGLARPSDILIDRWGVPHIFAANESDAFFVQGFNAARDRLFQIDLWRRRGLGQLAEVFGPAYVEQDKAARLFLYRGDMNAEWKRYGPDAKPVASRFAAGVNAYIDWLAAHPDQMPYEFRKVGYWPAKWSADDVVRIRSHGLTRNLTSEVARAKVACKSSLAADSVRFGLQPAWQPHSPEGLDPCLPDDVLKVFTLATQGVRITRESLKSADASATVIAAADNPEEVTEGSNNWVIAPAKSATGRAIMANDPHRAYAAPSLRYIQQISTPTLDIIGGGEPSAPGVSIGHNGAIAFGLTIFNIDQEDLYVYELNPANPRQYRYRDRWEPMRVVRETIDVRGGAPVVADLAFTRHGPVIYTEDAKHRAFAVRTAWLAPGMSPYFDSVRYMRAKNFTQFKQALSTWGAPTVNQVYADTHGDIGWVPSGLAPKRPNWDGLMPVPGDGRYEWAGFWPRDEMPSAYDPPDGYFTTSNEMNLPAGYSYGERKLGFEWTNGSRHQRIDEVLKALPKVSIEDSERLQNDIESIPARRLVALVAPLSSDDPDTRAALAMLKGWDAQMRADSPQAALEEIWLSRHLGRAFKQAVLPKAAAAAFAAPDTAVMLDSLEHPETRFGENAATKRDAVLLASLRDAYAEMVSLQGADAGQWQWGKLQTNLNAHPLADLVDADMRAKLNVGPTGKGGSAYTPNQSTYRASDFRQTNGPSFRVIVDVGNWDNSRAVNLPGESGDPDSPHYRDLATMWLNGEYFPLLYSRAAVEAAAEKRIRLVPGAQTR
>CP024942.1|AXE96537.1|2696758_2697769_+|deoxyribose-phosphate-aldolase
MPEAPSLSSSVIALRGGPLVHPVRNPGTPFDASWLDGLRVNQSAVERRTATLGTRRTVKKDAQAAWLLKAVTCIDLTTLNGDDTEGRVRRLCAKARQPVRADLLDALGIAPQGITTGAVCVYHRFVAAAVDALKGSGIPVAAVSTGFPAGLIPHPLKLKEIEASVADGAMEIDIVVTREHVLTGNWQALYDEVREFRAACGPAHLKTILATGDIRTLSNVARASMVCMMAGADFIKTSTGKEGVNATLDVSLVMVRMIREYQERTGVPIGFKPAGGVSTAKSVLSYQILMKEELGRAWLEPERFRIGASSLLADIERQLEHHVSGRYSAFNRHPVA
>CP024942.1|AXE96538.1|2697785_2700173_+|aldehyde-dehydrogenase
MSVAEYFSSMEYGPAPEDDQAARAWLARHAASFGHFIGGEWQAPAAGERFVSHAPATGERLAEIAQGDAADIDAAVAAARAAQPGWLALGGAGRARHLYALARMVQRHSRLFAVLEALDNGKPIRETRDIDVPLVARHFLHHAGWAQLQDSEFAAYAPLGVVGQIVPWNFPLLMLAWKIAPALATGNCVVLKPAEYTPLTALLFAELAHRAGLPAGVLNVVTGDGRTGAALVAHPQVDKIAFTGSTEVGRLIRQVTAGSGKSLTLELGGKSPFIVFDDADLDGAVEGVVDAIWFNQGQVCCAGSRLLVQEGIEARFIAKLKRRMQTLRAGTSLDKSIDIGAIVDPVQLERIESLVESGRREGCAVWQSSDAALPAGGCFYPPTLVTGVAPASTLAQEEIFGPVLVTMSFRTPDEAIALANNSRYGLAASVWSETIGRALDIAPRLQCGVVWINATNLFDAAVGFGGYRESGYGREGGREGIYEYLKPRAWLNLPKRRPVERAAHVEQRGEPSNVALIDRTAKLFIGGKQARPDSGYSLPVYAPDGTPVGEVGEGNRKDIRNAVEAARAAQKWSQASTHNRAQVLYYLAENLAVRADEFARQLVVRNGATEAAARAEVEAAVARLFTYAAWADKFDGAVHTPPLRGVALAMHEPLGVIGIACPDEAPLLGFVSLAAPALAMGNRVVVLPSEACPLAVTDFYQVVETSDVPGGVLNIVTGERAALLPALARHDDVDALWCFGNAADSALVERESIGNLKRTFVDHGRQFDWFDPASEGLPFLRQAVQVKNIWIPYGD
>CP024942.1|AXE96539.1|2700296_2701259_+|ribokinase
MNAPHERAGRVVILGIYVTDLTFRAERMPLIGETIAGSAFAMGPGGKGSNQAVAAARAGAKVVFCTRIGNDAFGAIARATWAAEGITARASVIDGVSTGAAHIFVDDTTGMNAIIVASGAAGTLNAADVDAIEADIAAAQVFVTQLEQPLAAARRGLEVARKHGVVTVFNPAPALPLDDGIFPLCDYITPNETEAAALTGVPIANADDARRAADVLLAKGVGTVVVTLGEGGALLHSATQSVLVPAYHCGRVVETAGAGDGFTGGFAAALARGDDAIAAMRFGCALAGISVTRAGTAPSMPTLDEVKRVLSQSDQTSQAL
>CP024942.1|AXE96540.1|2701326_2702364_+|sugar-ABC-transporter-permease
MFGGGKPFADRQLNFLLIVNVLVVLVATWLSRGQFVDIDNLQSMGGQLPELGLLALGIMLSMVSGNGGIDLSGVGLANLSGMVAALAVPHFVNGDDSPVLYTALFCSIVVVMGLLGGMLNGVVIAWLRLTPILCTLGTQLLFTGFAVVLSNGASVHVDYVDPLSAIGNGTVFQVPIAFCIFIAAVIVLGWLLKRSPFGLRLYLMGTNPKAAFYAGIPRARMLITTYAMCGVLASLAGLISATHTSSVKWDYGNSYLLIAILIAVMGGVNPAGGHGRIICVFFAATVLQFLSSLFNLLGVSQFFGDCAWGFLLLLSLAFAGGERVRAIFGFGGGGGAAGASAAPKR
>CP024942.1|AXE96541.1|2702474_2703479_+|autoinducer-2-ABC-transporter-substrate-binding-protein
MKLTRLGAALATGALAVGVIAAAQAATNETIVTVVKVTGINWFNRMDEGVKEFAKENPGVSAYQTGPGRADAAQQLKIIEDLIAKKVTAIAVVPYDPPTLEPALKKAMDRGIKVVTHEADNAKNTMVDIEAFDNTAYGAGLNERLASCMHSDGKWAVLVGSLGSRSQVQWADGGIGNAKGKYPKMNLVEPKLETNNDGERAYEVAKEVLRKHPDLKGFQGSSSLDVIGIGRAVEEAGMQGKICVYGTGLPTEAGKFLESGAINGIAFWDPKLAGEAMNKVAKMLVDGKTVENGADLGIPGYTKVTVAKGPGKGIIVRGQGWVNVDKSNYKQYPF
>CP024942.1|AXE97008.1|2703552_2705106_+|sugar-ABC-transporter-ATP-binding-protein
MNQDVSSSVQPEASRPFLQVAGVHKRFTGVHALRGVSLSFERGQIYHLLGENGCGKSTLIKIISGAQPPDEGELVIEGVRHARLSALEALAAGIETVYQDLSLLPNMSVAENVALTSELALHEGRLARTFDRRELARTAARALEAVGLPGDAEFQATLIEQLPLATRQLVAIARAIASEAKFVIMDEPTTSLTQKEVDNLIAVLANLRAQGVTVLFVSHKLDECYAIGGEVIVLRDGQKMAQGPIAQFTKAQISELMTGRHLSNERYREGGLGQDVVLDVRAFTRAGQFSDVSFRLHGGEILGITGLLDSGRNELARALAGVAPAQSGQVVLDGRRIALRTPSDAKRHRIGYVPEDRLNEGLFLDKPIRDNVITAMISSLRDRFGQIDRARAQALAEQTVKDLQIATPGVDKPVQSLSGGNQQRVLIGRWLAIDPRVLILHGPTVGVDVGSKDIIYRIMQRLSQRGIGIILISDDLPELLQNCDRILMMKKGRVASEYRADELSEADLYHALLSEAA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP024942_2	2.1\|2115295\|32\|CP024942\|CRISPRCasFinder	2115295-2115326	32	CP024942.1	2115374-2115405	1	0.969

1. spacer 2.1|2115295|32|CP024942|CRISPRCasFinder matches to position: 2115374-2115405, mismatch: 1, identity: 0.969

cagcgaccgcagggagcatgggggtcgtttca	CRISPR spacer
cagcgaccgcagggagcgtgggggtcgtttca	Protospacer
*****************.**************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

21716 : 48765

Cronobacter_phage(100.0%)

transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXE96802.1\|21716_22823_-\|transposase	transposase	NA	NA	NA	NA
AXE96803.1\|23574_24681_-\|transposase	transposase	NA	NA	NA	NA
AXE94448.1\|25034_25991_+	LysR family transcriptional regulator	NA	NA	NA	NA
AXE94449.1\|26033_27179_-	nucleoside hydrolase	NA	NA	NA	NA
AXE94450.1\|27360_28299_-	hypothetical protein	NA	NA	NA	NA
AXE94451.1\|28310_29270_+	D-alanyl-D-alanine carboxypeptidase	NA	NA	NA	NA
AXE94452.1\|29527_33394_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
AXE94453.1\|33390_34383_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
AXE94454.1\|34387_35341_+	flagellar motor protein MotB	NA	NA	NA	NA
AXE94455.1\|35436_36543_-	type VI secretion system protein TssA	NA	NA	NA	NA
AXE94456.1\|36615_39291_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	1.1e-88	31.0
AXE94457.1\|39325_40420_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
AXE94458.1\|40383_42222_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
AXE94459.1\|42376_42856_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
AXE94460.1\|42944_43448_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
AXE94461.1\|43520_45011_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
AXE94462.1\|45025_45574_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
AXE94463.1\|45611_46262_-	hypothetical protein	NA	NA	NA	NA
AXE96804.1\|46682_47309_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
AXE94464.1\|47418_48765_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

DBSCAN-SWA_2

243811 : 305995

Stx2-converting_phage(50.0%)

integrase,transposase

attL 243279:243294|attR 268668:268683

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
243279:243294	attL	NA	NA	NA	NA
AXE94623.1\|243811_244987_+\|integrase	integrase	NA	NA	NA	NA
AXE94624.1\|245177_245309_+	hypothetical protein	NA	NA	NA	NA
AXE94625.1\|245499_245835_+	hypothetical protein	NA	NA	NA	NA
AXE94626.1\|246466_246850_-	VOC family protein	NA	NA	NA	NA
AXE94627.1\|246902_247790_-	S-formylglutathione hydrolase	NA	NA	NA	NA
AXE94628.1\|247813_248920_-	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	A0A0K0KVL7	Prochlorococcus_phage	1.0e-32	28.3
AXE94629.1\|248945_249668_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
AXE94630.1\|249664_250834_-	CoA transferase	NA	NA	NA	NA
AXE94631.1\|250875_252237_-	serine--pyruvate aminotransferase	NA	NA	NA	NA
AXE94632.1\|252421_253537_-	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
AXE94633.1\|253618_254647_-	oxidoreductase	NA	NA	NA	NA
AXE94634.1\|254814_255747_-	LysR family transcriptional regulator	NA	NA	NA	NA
AXE94635.1\|258913_260137_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	1.4e-49	31.3
AXE94636.1\|262448_264047_+\|transposase	transposase	NA	NA	NA	NA
AXE94637.1\|266096_266693_-	plasmid pRiA4b ORF-3 family protein	NA	NA	NA	NA
AXE94638.1\|266704_268249_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	8.3e-137	48.4
AXE94639.1\|268300_268648_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBY2	Stx2-converting_phage	2.0e-35	63.6
AXE94640.1\|268644_269079_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-06	30.2
268668:268683	attR	NA	NA	NA	NA
AXE94641.1\|270291_270573_+	hypothetical protein	NA	NA	NA	NA
AXE94642.1\|270825_271092_-	hypothetical protein	NA	NA	NA	NA
AXE94643.1\|271144_271396_-	hypothetical protein	NA	NA	NA	NA
AXE94644.1\|272271_273942_+	nucleotide pyrophosphatase	NA	NA	NA	NA
AXE94645.1\|274380_275502_+	hypothetical protein	NA	NA	NA	NA
AXE94646.1\|275606_277037_-	malate permease	NA	NA	NA	NA
AXE94647.1\|277243_277525_-	hypothetical protein	NA	NA	NA	NA
AXE94648.1\|279874_281254_-	two-component sensor histidine kinase	NA	NA	NA	NA
AXE94649.1\|281229_281895_-	DNA-binding response regulator	NA	NA	NA	NA
AXE94650.1\|281920_282679_-	hypothetical protein	NA	NA	NA	NA
AXE94651.1\|282677_282962_+	hypothetical protein	NA	NA	NA	NA
AXE94652.1\|282968_283565_-	undecaprenyl-diphosphatase	NA	NA	NA	NA
AXE94653.1\|284855_285983_-	porin	NA	NA	NA	NA
AXE94654.1\|286069_286744_-	DNA-binding response regulator	Q6XM27	Feldmannia_irregularis_virus	5.1e-06	29.6
AXE96816.1\|287324_287603_+	hypothetical protein	NA	NA	NA	NA
AXE94655.1\|287988_289104_+	glycosyltransferase family 1 protein	NA	NA	NA	NA
AXE96817.1\|289100_289928_+	hypothetical protein	NA	NA	NA	NA
AXE94656.1\|289943_290768_-	hypothetical protein	NA	NA	NA	NA
AXE94657.1\|290757_292098_-	glycosyl transferase	NA	NA	NA	NA
AXE96818.1\|292110_292461_-	hypothetical protein	NA	NA	NA	NA
AXE94658.1\|292821_293481_+	DNA-binding response regulator	NA	NA	NA	NA
AXE94659.1\|293481_294930_+	two-component sensor histidine kinase	NA	NA	NA	NA
AXE94660.1\|294926_295991_-	hypothetical protein	NA	NA	NA	NA
AXE94661.1\|296090_297251_-	glucosyltransferase	NA	NA	NA	NA
AXE94662.1\|297247_298669_-	hopanoid biosynthesis associated radical SAM protein HpnJ	NA	NA	NA	NA
AXE94663.1\|299582_300179_-	plasmid pRiA4b ORF-3 family protein	NA	NA	NA	NA
AXE94664.1\|300190_301735_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	2.4e-136	48.3
AXE94665.1\|301786_302134_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBY2	Stx2-converting_phage	2.0e-35	63.6
AXE94666.1\|302130_302565_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-06	30.2
AXE94667.1\|303622_304570_+	hypothetical protein	A0A0P0C6Y6	Ostreococcus_lucimarinus_virus	2.5e-11	29.3
AXE94668.1\|305093_305396_+\|transposase	transposase	A9YX41	Burkholderia_phage	8.0e-28	67.3
AXE94669.1\|305392_305995_+	hypothetical protein	Q716C2	Shigella_phage	2.5e-33	43.2

DBSCAN-SWA_3

345260 : 445046

Bacillus_phage(33.33%)

integrase,transposase

attL 396630:396654|attR 399997:400021

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXE96821.1\|345260_346361_+\|transposase	IS110 family transposase	NA	NA	NA	NA
AXE94688.1\|346991_348161_-\|transposase	IS91 family transposase	NA	NA	NA	NA
AXE94689.1\|348182_348422_-	hypothetical protein	NA	NA	NA	NA
AXE94690.1\|348464_349988_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	5.5e-149	52.4
AXE94691.1\|350000_350768_+	AAA family ATPase	K4HZD4	Acidithiobacillus_phage	3.0e-71	54.6
AXE94692.1\|353492_353918_+	CopG family transcriptional regulator	NA	NA	NA	NA
AXE94693.1\|353960_355064_+	poly(3-hydroxyalkanoate) depolymerase	NA	NA	NA	NA
AXE94694.1\|355818_356091_+	hypothetical protein	NA	NA	NA	NA
AXE94695.1\|356133_356547_+	HicB family protein	NA	NA	NA	NA
AXE94696.1\|356709_356916_+	hypothetical protein	NA	NA	NA	NA
AXE94697.1\|357266_357503_+	hypothetical protein	NA	NA	NA	NA
AXE94698.1\|357739_357946_-	hypothetical protein	NA	NA	NA	NA
AXE94699.1\|358274_358460_-	hypothetical protein	NA	NA	NA	NA
AXE94700.1\|359000_359288_-	DUF1488 domain-containing protein	NA	NA	NA	NA
AXE94701.1\|359254_359446_-	hypothetical protein	NA	NA	NA	NA
AXE94702.1\|361211_362027_+\|transposase	transposase	A0A1B1P8D0	Bacillus_phage	2.3e-08	30.4
AXE94703.1\|362165_363764_+\|transposase	transposase	NA	NA	NA	NA
AXE94704.1\|365262_365757_-	phasin	NA	NA	NA	NA
AXE94705.1\|366121_366301_-	hypothetical protein	NA	NA	NA	NA
AXE94706.1\|366879_367314_-	ketosteroid isomerase	NA	NA	NA	NA
AXE94707.1\|367389_368058_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AXE94708.1\|368265_369918_-	hypothetical protein	NA	NA	NA	NA
AXE94709.1\|370072_371092_+	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
AXE94710.1\|371167_371941_+	hydroxypyruvate isomerase	NA	NA	NA	NA
AXE94711.1\|372025_373036_+	inositol 2-dehydrogenase	NA	NA	NA	NA
AXE94712.1\|373926_374724_-	alpha/beta hydrolase	NA	NA	NA	NA
AXE94713.1\|375030_375339_-	hypothetical protein	NA	NA	NA	NA
AXE96822.1\|376219_377320_+\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AXE94714.1\|381275_381461_+	hypothetical protein	NA	NA	NA	NA
AXE96823.1\|381530_381965_+	universal stress protein	NA	NA	NA	NA
AXE94715.1\|383321_383639_-	DUF1840 domain-containing protein	NA	NA	NA	NA
AXE94716.1\|384648_386502_+	thiamine pyrophosphate-requiring protein	NA	NA	NA	NA
AXE94717.1\|386535_387657_+	mandelate racemase	NA	NA	NA	NA
AXE94718.1\|387687_388713_+	hypothetical protein	NA	NA	NA	NA
AXE94719.1\|388709_389375_+	gluconate 2-dehydrogenase	NA	NA	NA	NA
AXE94720.1\|391590_392961_+	MFS transporter	NA	NA	NA	NA
AXE94721.1\|393482_393833_-	hypothetical protein	NA	NA	NA	NA
AXE94722.1\|394377_394650_+	hypothetical protein	NA	NA	NA	NA
AXE94723.1\|395020_395836_-\|transposase	transposase	A0A1B1P8D0	Bacillus_phage	2.3e-08	30.4
396630:396654	attL	NA	NA	NA	NA
AXE94724.1\|396720_397716_-\|integrase	integrase	A0A1D6X8B0	Bacillus_phage	5.2e-07	21.8
AXE94725.1\|397708_398650_-\|integrase	integrase	NA	NA	NA	NA
AXE96824.1\|398646_399612_-\|integrase	integrase	NA	NA	NA	NA
AXE94726.1\|400970_402569_+\|transposase	transposase	NA	NA	NA	NA
399997:400021	attR	NA	NA	NA	NA
AXE94727.1\|403500_404394_+	hypothetical protein	NA	NA	NA	NA
AXE94728.1\|404320_404605_-	DUF3303 domain-containing protein	NA	NA	NA	NA
AXE94729.1\|405183_406575_-	hypothetical protein	NA	NA	NA	NA
AXE94730.1\|407446_408628_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AXE94731.1\|410041_410785_+	hypothetical protein	NA	NA	NA	NA
AXE94732.1\|410812_411948_-\|transposase	IS3 family transposase	NA	NA	NA	NA
AXE94733.1\|411880_412456_+	hypothetical protein	NA	NA	NA	NA
AXE94734.1\|412709_412982_+	hypothetical protein	NA	NA	NA	NA
AXE94735.1\|413537_414212_-	hypothetical protein	NA	NA	NA	NA
AXE96825.1\|417277_418300_-\|transposase	IS110 family transposase	NA	NA	NA	NA
AXE94736.1\|418696_419374_+	hypothetical protein	NA	NA	NA	NA
AXE94737.1\|419373_419718_+	hypothetical protein	NA	NA	NA	NA
AXE94738.1\|419881_420157_+	hypothetical protein	NA	NA	NA	NA
AXE94739.1\|420125_420752_-	hypothetical protein	A0A0E3M0Y2	Rhodoferax_phage	3.7e-11	45.3
AXE94740.1\|420748_421300_-	hypothetical protein	A0A0E3JI96	Rhodoferax_phage	2.2e-52	58.6
AXE94741.1\|421451_421994_+	hypothetical protein	NA	NA	NA	NA
AXE94742.1\|421990_422377_+	hypothetical protein	NA	NA	NA	NA
AXE96826.1\|422361_423138_+	dinucleotide-utilizing protein	NA	NA	NA	NA
AXE94743.1\|423217_423415_+	excisionase	NA	NA	NA	NA
AXE94744.1\|423417_424503_+	hypothetical protein	A0A2H4IYC8	uncultured_Caudovirales_phage	3.9e-48	35.4
AXE94745.1\|424759_425677_-	LysR family transcriptional regulator	NA	NA	NA	NA
AXE96827.1\|426022_427120_+\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AXE94746.1\|427494_427932_-	response regulator	NA	NA	NA	NA
AXE94747.1\|428105_428456_-	hypothetical protein	NA	NA	NA	NA
AXE94748.1\|428726_429278_-	DNA-binding response regulator	NA	NA	NA	NA
AXE94749.1\|429680_430985_+	MFS transporter	NA	NA	NA	NA
AXE94750.1\|431125_431398_-	hypothetical protein	NA	NA	NA	NA
AXE94751.1\|431462_431894_-	DoxX family protein	NA	NA	NA	NA
AXE94752.1\|432042_432504_-	ribose ABC transporter	NA	NA	NA	NA
AXE94753.1\|432959_433328_-	polyketide cyclase	NA	NA	NA	NA
AXE94754.1\|433444_434338_+	XRE family transcriptional regulator	NA	NA	NA	NA
AXE94755.1\|434421_434958_+	N-acetyltransferase	NA	NA	NA	NA
AXE94756.1\|435649_435970_+	flagellar transcriptional regulator FlhD	NA	NA	NA	NA
AXE94757.1\|435984_436554_+	flagellar transcriptional regulator FlhC	NA	NA	NA	NA
AXE94758.1\|436699_438028_-	divalent metal cation transporter	NA	NA	NA	NA
AXE94759.1\|438095_439298_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
AXE94760.1\|439358_440015_-	ABC transporter permease	NA	NA	NA	NA
AXE94761.1\|440007_441165_-	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.8e-27	37.3
AXE94762.1\|441178_442585_-	N5,N10-methylene tetrahydromethanopterin reductase	NA	NA	NA	NA
AXE94763.1\|442627_443467_-	methionine ABC transporter substrate-binding protein	NA	NA	NA	NA
AXE96828.1\|443945_445046_+\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

2325473 : 2366090

uncultured_virus(33.33%)

bacteriocin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXE96249.1\|2325473_2327696_+\|bacteriocin	bacteriocin biosynthesis cyclodehydratase	NA	NA	NA	NA
AXE96250.1\|2328377_2328578_+	hypothetical protein	NA	NA	NA	NA
AXE96251.1\|2328826_2329399_+	Phasin (PHA-granule associated protein)	NA	NA	NA	NA
AXE96252.1\|2329562_2330306_+	beta-ketoacyl-ACP reductase	NA	NA	NA	NA
AXE96983.1\|2330583_2331966_-	DNA polymerase Y family protein	NA	NA	NA	NA
AXE96253.1\|2331982_2332690_-	recombinase RecA	NA	NA	NA	NA
AXE96254.1\|2332984_2333986_+	short-chain dehydrogenase	NA	NA	NA	NA
AXE96255.1\|2334007_2334661_-	DUF1109 domain-containing protein	NA	NA	NA	NA
AXE96984.1\|2334657_2335185_-	RNA polymerase subunit sigma	NA	NA	NA	NA
AXE96256.1\|2335451_2335772_+	hypothetical protein	NA	NA	NA	NA
AXE96257.1\|2335785_2336676_+	hypothetical protein	NA	NA	NA	NA
AXE96258.1\|2336647_2337454_+	DUF2063 domain-containing protein	NA	NA	NA	NA
AXE96259.1\|2337459_2337942_+	DoxX family protein	NA	NA	NA	NA
AXE96260.1\|2338391_2338751_+	hypothetical protein	NA	NA	NA	NA
AXE96261.1\|2338844_2340140_+	TolC family protein	NA	NA	NA	NA
AXE96262.1\|2340151_2341702_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
AXE96263.1\|2341698_2344902_+	CusA/CzcA family heavy metal efflux RND transporter	NA	NA	NA	NA
AXE96264.1\|2344898_2345234_+	RND transporter MFP subunit	NA	NA	NA	NA
AXE96265.1\|2345327_2345684_+	hypothetical protein	NA	NA	NA	NA
AXE96266.1\|2345816_2346131_+	hypothetical protein	NA	NA	NA	NA
AXE96267.1\|2346232_2346550_+	P-II family nitrogen regulator	NA	NA	NA	NA
AXE96268.1\|2346608_2348852_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.2e-67	33.2
AXE96269.1\|2348985_2349237_-	hypothetical protein	NA	NA	NA	NA
AXE96985.1\|2349261_2349645_-	hypothetical protein	NA	NA	NA	NA
AXE96270.1\|2349868_2350204_-	hypothetical protein	NA	NA	NA	NA
AXE96271.1\|2350259_2350616_-	hypothetical protein	NA	NA	NA	NA
AXE96272.1\|2351084_2351471_+	response regulator	NA	NA	NA	NA
AXE96986.1\|2351691_2353893_+	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
AXE96273.1\|2353882_2354557_+	DNA-binding response regulator	NA	NA	NA	NA
AXE96274.1\|2356528_2356981_-	XRE family transcriptional regulator	NA	NA	NA	NA
AXE96275.1\|2357469_2358324_+	hypothetical protein	NA	NA	NA	NA
AXE96276.1\|2359687_2360839_+\|transposase	IS110 family transposase	NA	NA	NA	NA
AXE96277.1\|2361305_2362112_+\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AXE96278.1\|2362542_2363694_-\|transposase	IS110 family transposase	NA	NA	NA	NA
AXE96279.1\|2363789_2364547_-\|transposase	IS5/IS1182 family transposase	A0A0N9SHJ4	Paenibacillus_phage	4.5e-19	38.7
AXE96280.1\|2364662_2366090_+\|transposase	IS4 family transposase	Q9JMP3	Wolbachia_phage	3.4e-60	32.6

DBSCAN-SWA_5

2782184 : 2843194

Bacillus_phage(60.0%)

integrase,transposase,protease

attL 2841174:2841198|attR 2844539:2844563

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXE96600.1\|2782184_2783282_-\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AXE96601.1\|2783914_2785096_+	porin	NA	NA	NA	NA
AXE96602.1\|2785524_2788851_+	diguanylate phosphodiesterase	NA	NA	NA	NA
AXE96603.1\|2790261_2790909_-	isoprenylcysteine carboxyl methyltransferase	NA	NA	NA	NA
AXE97017.1\|2790905_2791889_-	pilus assembly protein TadE	NA	NA	NA	NA
AXE97018.1\|2792000_2792444_-	pilus assembly protein	NA	NA	NA	NA
AXE96604.1\|2792452_2793340_-	hypothetical protein	NA	NA	NA	NA
AXE96605.1\|2793420_2794383_-	fimbrial protein	NA	NA	NA	NA
AXE96606.1\|2794379_2795357_-	secretion system protein	NA	NA	NA	NA
AXE96607.1\|2795353_2796763_-	CpaF family protein	NA	NA	NA	NA
AXE96608.1\|2796762_2797980_-	pilus assembly protein CpaE	NA	NA	NA	NA
AXE97019.1\|2798007_2798343_-	hypothetical protein	NA	NA	NA	NA
AXE96609.1\|2798420_2799887_-	fimbrial protein	NA	NA	NA	NA
AXE96610.1\|2799934_2800897_-	Flp pilus assembly protein CpaB	NA	NA	NA	NA
AXE96611.1\|2800909_2801407_-	peptidase A24A prepilin type IV	NA	NA	NA	NA
AXE96612.1\|2801481_2801664_-	Flp family type IVb pilin	NA	NA	NA	NA
AXE96613.1\|2801999_2803097_-\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AXE96614.1\|2803556_2805095_+	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	1.1e-16	38.9
AXE96615.1\|2807268_2807865_+	hypothetical protein	NA	NA	NA	NA
AXE96616.1\|2808802_2811556_+	magnesium-translocating P-type ATPase	A0A1J0FA34	Only_Syngen_Nebraska_virus	5.2e-41	24.5
AXE97020.1\|2811773_2812886_+	porin	NA	NA	NA	NA
AXE96617.1\|2814960_2815971_-\|transposase	IS110 family transposase	NA	NA	NA	NA
AXE96618.1\|2817514_2818279_-	enoyl-CoA hydratase	NA	NA	NA	NA
AXE96619.1\|2818336_2819674_-	hypothetical protein	NA	NA	NA	NA
AXE96620.1\|2819670_2821365_-	peptide synthetase	A0A2K9KZV5	Tupanvirus	1.6e-45	25.3
AXE96621.1\|2822170_2822356_-	hypothetical protein	NA	NA	NA	NA
AXE96622.1\|2822398_2823160_-	hypothetical protein	NA	NA	NA	NA
AXE96623.1\|2823985_2824744_+	hypothetical protein	NA	NA	NA	NA
AXE96624.1\|2824810_2826220_+\|protease	serine protease	A0A217EQY2	Bacillus_phage	1.2e-25	36.6
AXE96625.1\|2826352_2826685_+	hypothetical protein	NA	NA	NA	NA
AXE96626.1\|2827245_2827788_+	hypothetical protein	NA	NA	NA	NA
AXE96627.1\|2827888_2829766_-	hypothetical protein	NA	NA	NA	NA
AXE96628.1\|2829792_2832381_-	hypothetical protein	NA	NA	NA	NA
AXE96629.1\|2832301_2833468_-	hypothetical protein	NA	NA	NA	NA
AXE96630.1\|2833734_2835477_-	hypothetical protein	NA	NA	NA	NA
AXE96631.1\|2835718_2838544_+	hypothetical protein	NA	NA	NA	NA
AXE96632.1\|2840642_2841023_+	hypothetical protein	NA	NA	NA	NA
2841174:2841198	attL	NA	NA	NA	NA
AXE96633.1\|2841264_2842260_-\|integrase	integrase	A0A1D6X8B0	Bacillus_phage	5.2e-07	21.8
AXE96634.1\|2842252_2843194_-\|integrase	integrase	NA	NA	NA	NA
2844539:2844563	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP024941

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP024942

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection