CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP030325	Staphylococcus aureus strain AR_474 plasmid unnamed1, complete sequence	0 crisprs	csa3	0	0	1	0
CP030326	Staphylococcus aureus strain AR_474 chromosome, complete genome	8 crisprs	cas3,DEDDh,DinG,csa3,RT,WYL	9	3	10	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

11027 : 18100

Staphylococcus_phage(42.86%)

integrase,transposase

attL 14743:14799|attR 18101:18157

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ65049.1\|11027_12434_+	6-phosphogluconate dehydrogenase	A0A0P0C6S9	Ostreococcus_lucimarinus_virus	2.0e-41	29.0
AWZ65052.1\|12497_13958_+	glucose-6-phosphate dehydrogenase	M4SIY3	Cyanophage	1.4e-72	36.1
AWZ65038.1\|14067_14742_-	DDE domain protein	A0A0N9RU54	Staphylococcus_phage	3.8e-126	98.2
14743:14799	attL	NA	NA	NA	NA
AWZ65033.1\|14869_15154_+\|transposase	transposase, Mutator family protein	A0A1X9I6M5	Streptococcus_phage	2.2e-48	100.0
AWZ65043.1\|15283_16723_-	bifunctional AAC/APH	A0A1X9I6C2	Streptococcus_phage	3.8e-285	100.0
AWZ65062.1\|16723_17128_-	acetyltransferase family protein	A0A0N7GFH7	Staphylococcus_phage	3.4e-74	100.0
AWZ65061.1\|17425_18100_-\|integrase	integrase core domain protein	A0A0N9RU54	Staphylococcus_phage	3.8e-126	98.2
18101:18157	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP030326

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CRISPR-Cas detection and classification

Crispr_ID: CP030326_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030326_1

462910-463011

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP030326_1

>merge|CP030326|1|462910-463011|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>CP030326|1|1|462910-463011|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
CP030326.1\|AWZ66075.1\|457226_458750_-\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
CP030326.1\|AWZ66778.1\|459826_460582_+\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
CP030326.1\|AWZ67032.1\|463027_463984_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
CP030326.1\|AWZ67272.1\|458765_459335_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
CP030326.1\|AWZ67048.1\|455503_455887_-\|putative-membrane-protein	unknown	unknown	unknown
CP030326.1\|AWZ67253.1\|469201_470743_+\|GMP-synthase	unknown	unknown	gnl\|CDD\|234614
CP030326.1\|AWZ67365.1\|464101_464764_-\|hypothetical-protein	unknown	unknown	unknown
CP030326.1\|AWZ67582.1\|465826_466405_+\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
CP030326.1\|AWZ67547.1\|454856_455438_+\|histidine-phosphatase-super-family-protein	unknown	unknown	gnl\|CDD\|223483
CP030326.1\|AWZ67566.1\|456855_457047_-\|hypothetical-protein	unknown	unknown	unknown
CP030326.1\|AWZ66664.1\|466443_467673_+\|xanthine-permease-family-protein	unknown	unknown	gnl\|CDD\|274468
CP030326.1\|AWZ65948.1\|470855_471392_-\|hypothetical-protein	unknown	unknown	unknown
CP030326.1\|AWZ67628.1\|467710_469177_+\|inosine-5'-monophosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
CP030326.1\|AWZ67687.1\|464906_465314_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378584
CP030326.1\|AWZ65403.1\|471783_472488_-\|pemK-like-family-protein	unknown	unknown	gnl\|CDD\|367091
CP030326.1\|AWZ67516.1\|454179_454431_+\|transglycosylase-associated-family-protein	unknown	unknown	gnl\|CDD\|225170
CP030326.1\|AWZ66382.1\|456156_456783_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380196
CP030326.1\|AWZ66432.1\|460661_462050_-\|L-cystine-uptake-protein-TcyP	unknown	unknown	gnl\|CDD\|224736
CP030326.1\|AWZ67389.1\|453616_453874_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238045
CP030326.1\|AWZ66717.1\|472886_473114_-\|putative-transposase	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP030326.1\|AWZ66075.1\|457226_458750_-\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
CP030326.1\|AWZ66778.1\|459826_460582_+\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	4.50551e-88
CP030326.1\|AWZ67032.1\|463027_463984_-\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00265416
CP030326.1\|AWZ67272.1\|458765_459335_-\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
CP030326.1\|AWZ67253.1\|469201_470743_+\|GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
CP030326.1\|AWZ67547.1\|454856_455438_+\|histidine-phosphatase-super-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.4566e-49
CP030326.1\|AWZ67582.1\|465826_466405_+\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	1.38815e-118
CP030326.1\|AWZ66664.1\|466443_467673_+\|xanthine-permease-family-protein	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	6.14613e-166
CP030326.1\|AWZ67628.1\|467710_469177_+\|inosine-5'-monophosphate-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
CP030326.1\|AWZ67687.1\|464906_465314_-\|hypothetical-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.17298e-12
CP030326.1\|AWZ65403.1\|471783_472488_-\|pemK-like-family-protein	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	5.38181e-08
CP030326.1\|AWZ67516.1\|454179_454431_+\|transglycosylase-associated-family-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.58864e-09
CP030326.1\|AWZ66382.1\|456156_456783_-\|hypothetical-protein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.15385e-71
CP030326.1\|AWZ66432.1\|460661_462050_-\|L-cystine-uptake-protein-TcyP	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
CP030326.1\|AWZ67389.1\|453616_453874_-\|hypothetical-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.00426296

>CP030326.1|AWZ66432.1|460661_462050_-|L-cystine-uptake-protein-TcyP
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLVYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFESNDNAALTSH
>CP030326.1|AWZ66778.1|459826_460582_+|NADPH-dependent-oxidoreductase
MSDYVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>CP030326.1|AWZ67272.1|458765_459335_-|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>CP030326.1|AWZ66075.1|457226_458750_-|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDEKSKELKELLTEISDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKNLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMSTGEEHLLNLDGIFVQIGLLPNTSWLKDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>CP030326.1|AWZ67566.1|456855_457047_-|hypothetical-protein
MNEIIMLLRTIPTSKLIQPIMQLFIDNAILNIVQNDALLIEKATHARNHLRLWSLQGHRDIPN
>CP030326.1|AWZ66382.1|456156_456783_-|hypothetical-protein
MKKRLLLSTFLASALILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>CP030326.1|AWZ67048.1|455503_455887_-|putative-membrane-protein
MKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNIILMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFISAIITLAIGGKSVDKNDSH
>CP030326.1|AWZ67547.1|454856_455438_+|histidine-phosphatase-super-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSREEAVDLKVENCKPYIIE
>CP030326.1|AWZ67516.1|454179_454431_+|transglycosylase-associated-family-protein
MFGFIGMLIVGGLIGWAAGAIMGKDIPGGILGNIIAGIIGSWVGGKLFGQWGPELGSIYILPALIGSIILIAIVTLILRAMRK
>CP030326.1|AWZ67389.1|453616_453874_-|hypothetical-protein
MHILYNLRTKHNLEIDELAQQLNEKYGTKYEAHQIWEWENHHHEPKFKDAMHLADFFDAPYEMFLESKVKEYQKHLEEVDIRMDK
>CP030326.1|AWZ67032.1|463027_463984_-|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKVLAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNENAAETSNKEATVDADAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>CP030326.1|AWZ67365.1|464101_464764_-|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>CP030326.1|AWZ67687.1|464906_465314_-|hypothetical-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHKEVQEHNSAYEEIDITHFAEASKGPKA
>CP030326.1|AWZ67582.1|465826_466405_+|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVVEE
>CP030326.1|AWZ66664.1|466443_467673_+|xanthine-permease-family-protein
MYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILVLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>CP030326.1|AWZ67628.1|467710_469177_+|inosine-5'-monophosphate-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>CP030326.1|AWZ67253.1|469201_470743_+|GMP-synthase
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>CP030326.1|AWZ65948.1|470855_471392_-|hypothetical-protein
MHNKNEFNKKLKDFIGSDKRMALVKGYINEYKLTTVLRALNNSDYTKGTIHTRSIGNLKQIVDNRIIPKNITQNKIFKLSNLTLEVNLYERNTIYHGDFAIYYPVESALIIETDTPRLINHINNNPVQKIFIITTNDWSFNTLELEKIVDETIIYDLKQEDPKQYEILYKNKHGKLPY
>CP030326.1|AWZ65403.1|471783_472488_-|pemK-like-family-protein
MSKNINQANSKLNTSNKKLKQAYSKSDSKNMKVIYMPHWLEFYSIAIHSDVTSNKKRYYKSFSRGTVVYVKLGSNIGSEFSGNHFCVILDNKDNKGKETVTIVPLSSKGNKNYLKLNESVLNLTATDLKKQIIDISSKVQALTQKYRDIDIKLSTEDKKLLSNLNQKANELYRVIGVYSKHKGKDTYVNISAITTISKRRISKINDSDPTGTIIISEDDMNEIEKQLKIKFFSN
>CP030326.1|AWZ66717.1|472886_473114_-|putative-transposase
MVRLYKNGKLKNEIIRKYDLKPSIISNSIKQHQNTGPFNHQDNLKSDEKELIKLRKEVQHLKMEHDVLKQILKLI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP030326_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030326_2

818452-818534

Orphan

Consensus_repeat	Method
CCAATTTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP030326_2

>merge|CP030326|2|818452-818534|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACATAGAGAAATTGGAACGCCAATTTCTACAGACAATGCAAGTTGG

>CP030326|2|2|818452-818534|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACATAGAGAAATTGGAACG
CCAATTTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
CP030326.1\|AWZ65194.1\|826985_827957_+\|ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
CP030326.1\|AWZ65931.1\|813639_814617_+\|ABC-transporter-family-protein	unknown	unknown	gnl\|CDD\|224050
CP030326.1\|AWZ66797.1\|817760_818303_+\|putative-5'(3')-deoxyribonucleotidase	unknown	unknown	gnl\|CDD\|226895
CP030326.1\|AWZ66696.1\|822734_823601_-\|eamA-like-transporter-family-protein	unknown	unknown	gnl\|CDD\|223769
CP030326.1\|AWZ66017.1\|809747_811625_+\|heme-ABC-exporter,-ATP-binding-protein-CcmA	unknown	unknown	gnl\|CDD\|223562
CP030326.1\|AWZ65414.1\|816363_817422_+\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|235106
CP030326.1\|AWZ66067.1\|814609_816124_+\|substrate-binding-domain-of-ABC-type-glycine-betaine-transport-system-family-protein	unknown	unknown	gnl\|CDD\|270328
CP030326.1\|AWZ67020.1\|806053_807058_+\|allophanate-hydrolase-subunit-2-family-protein	unknown	unknown	gnl\|CDD\|224895
CP030326.1\|AWZ65549.1\|805359_806070_+\|allophanate-hydrolase-subunit-1-family-protein	unknown	unknown	gnl\|CDD\|224960
CP030326.1\|AWZ67605.1\|824401_824800_+\|nrdI-protein	unknown	unknown	gnl\|CDD\|224694
CP030326.1\|AWZ67482.1\|824771_826868_+\|ribonucleoside-diphosphate-reductase,-alpha-subunit	unknown	unknown	gnl\|CDD\|236069
CP030326.1\|AWZ66076.1\|820368_821874_-\|H+-symporter-family-protein	unknown	unknown	gnl\|CDD\|225646
CP030326.1\|AWZ67145.1\|822214_822715_-\|7-cyano-7-deazaguanine-reductase	unknown	unknown	gnl\|CDD\|223851
CP030326.1\|AWZ66768.1\|811639_813418_+\|ATP-dependent-DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|273594
CP030326.1\|AWZ67368.1\|819181_820099_-\|putative-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
CP030326.1\|AWZ67451.1\|830242_831004_+\|ABC-transporter-family-protein	unknown	unknown	gnl\|CDD\|226963
CP030326.1\|AWZ66606.1\|829289_830246_+\|fecCD-transport-family-protein	unknown	unknown	gnl\|CDD\|226964
CP030326.1\|AWZ66847.1\|828331_829303_+\|fecCD-transport-family-protein	unknown	unknown	gnl\|CDD\|226965
CP030326.1\|AWZ66642.1\|804391_805000_+\|aminotransferase-class-IV-family-protein	unknown	unknown	gnl\|CDD\|376449
CP030326.1\|AWZ67637.1\|807531_809472_+\|lipoteichoic-acid-synthase	unknown	unknown	gnl\|CDD\|224287

Protein	Function_ID	Function_description	E-value
CP030326.1\|AWZ65194.1\|826985_827957_+\|ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.30551e-164
CP030326.1\|AWZ65931.1\|813639_814617_+\|ABC-transporter-family-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	8.50045e-155
CP030326.1\|AWZ66797.1\|817760_818303_+\|putative-5'(3')-deoxyribonucleotidase	gnl\|CDD\|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	3.14113e-108
CP030326.1\|AWZ66696.1\|822734_823601_-\|eamA-like-transporter-family-protein	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.04233e-10
CP030326.1\|AWZ66017.1\|809747_811625_+\|heme-ABC-exporter,-ATP-binding-protein-CcmA	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
CP030326.1\|AWZ65414.1\|816363_817422_+\|histidinol-phosphate-transaminase	gnl\|CDD\|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0
CP030326.1\|AWZ66067.1\|814609_816124_+\|substrate-binding-domain-of-ABC-type-glycine-betaine-transport-system-family-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.03165e-152
CP030326.1\|AWZ67020.1\|806053_807058_+\|allophanate-hydrolase-subunit-2-family-protein	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.66238e-142
CP030326.1\|AWZ65549.1\|805359_806070_+\|allophanate-hydrolase-subunit-1-family-protein	gnl\|CDD\|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	1.34598e-94
CP030326.1\|AWZ67605.1\|824401_824800_+\|nrdI-protein	gnl\|CDD\|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	5.52807e-56
CP030326.1\|AWZ67482.1\|824771_826868_+\|ribonucleoside-diphosphate-reductase,-alpha-subunit	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
CP030326.1\|AWZ66076.1\|820368_821874_-\|H+-symporter-family-protein	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.22605e-172
CP030326.1\|AWZ67145.1\|822214_822715_-\|7-cyano-7-deazaguanine-reductase	gnl\|CDD\|223851	COG0780, COG0780, Enzyme related to GTP cyclohydrolase I [General function prediction only].	7.91282e-79
CP030326.1\|AWZ66768.1\|811639_813418_+\|ATP-dependent-DNA-helicase-RecQ	gnl\|CDD\|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
CP030326.1\|AWZ67368.1\|819181_820099_-\|putative-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	7.55646e-79
CP030326.1\|AWZ67451.1\|830242_831004_+\|ABC-transporter-family-protein	gnl\|CDD\|226963	COG4604, CeuD, ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism].	1.22383e-150
CP030326.1\|AWZ66606.1\|829289_830246_+\|fecCD-transport-family-protein	gnl\|CDD\|226964	COG4605, CeuC, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	4.81847e-122
CP030326.1\|AWZ66847.1\|828331_829303_+\|fecCD-transport-family-protein	gnl\|CDD\|226965	COG4606, CeuB, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	1.32603e-150
CP030326.1\|AWZ66642.1\|804391_805000_+\|aminotransferase-class-IV-family-protein	gnl\|CDD\|376449	pfam01063, Aminotran_4, Amino-transferase class IV. The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.	5.60043e-39
CP030326.1\|AWZ67637.1\|807531_809472_+\|lipoteichoic-acid-synthase	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0

>CP030326.1|AWZ66797.1|817760_818303_+|putative-5'(3')-deoxyribonucleotidase
MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPHAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
>CP030326.1|AWZ65414.1|816363_817422_+|histidinol-phosphate-transaminase
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>CP030326.1|AWZ66067.1|814609_816124_+|substrate-binding-domain-of-ABC-type-glycine-betaine-transport-system-family-protein
MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILLTKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRFMAKLSYKKLLMTLGVIVMIIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMKYNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNLDNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKESFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK
>CP030326.1|AWZ65931.1|813639_814617_+|ABC-transporter-family-protein
MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTLKMINRLIHLSEGYIYFKDKPISDCPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQMKKWKEKDIDKRVDELLDMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMDEPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQIDTPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTSMSAYPIVYDNQPIEVLYQHLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD
>CP030326.1|AWZ66768.1|811639_813418_+|ATP-dependent-DNA-helicase-RecQ
MQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYFLNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVEELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
>CP030326.1|AWZ66017.1|809747_811625_+|heme-ABC-exporter,-ATP-binding-protein-CcmA
MEAYKIEHLNKSYADKTIFDNLDLSISEGEKIGLVGINGTGKSTLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQYEQAVQAYADDQSDKLFKRMIDAQDAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKELSGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYFLNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAGAKARTTKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKVLFEHLTEIIQKGERIGVVGPNGAGKTTLLNILSGEDQQFEGKLKTGQTVKVAYFKQTDETLDRDIRMIDYLREESEVAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKRLYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQSYWFIHDGQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSYTTVRKKNGLSYKEKLEYEQLMKRIEQAEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIKEQQ
>CP030326.1|AWZ67637.1|807531_809472_+|lipoteichoic-acid-synthase
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
>CP030326.1|AWZ67020.1|806053_807058_+|allophanate-hydrolase-subunit-2-family-protein
MSIIIEKSGLFSSFQGFGRRGYEHDGVIPCGALDTLAHEIANRLVANDKNEATLEMTNKMATIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLKFRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTARHHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVVKNKGTEDFKEDAIQRFVKHDYKVTSKANRMGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQIGTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
>CP030326.1|AWZ65549.1|805359_806070_+|allophanate-hydrolase-subunit-1-family-protein
MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIEIVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYGSKYGPDIESLLKHYKIKLETFIELHSKTQYFVSMMGYSPGFPYLTGLNKKLYINHTSKQKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFRPINENELEVGAFKDVNHN
>CP030326.1|AWZ66642.1|804391_805000_+|aminotransferase-class-IV-family-protein
MQLFETMKIDNGHIPRLTYHTNRIKCSSERLNFKFDEHAWRNELNDVTTKYHSGQYRLKIVLNAESKFETIVSPLPEKSSFTAKFQVLPKVVNPTFIKNKTTERKHLAHNHETDLILLTSEDGKVLEFDIGNIVIEEDGKWYTPSYKDDFLKGCMRDYLIDSDKLVEKDFNKNELIYKYHNNEIRLFLINSLREVADVHLCL
>CP030326.1|AWZ67368.1|819181_820099_-|putative-lipid-kinase
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMSHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>CP030326.1|AWZ66076.1|820368_821874_-|H+-symporter-family-protein
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>CP030326.1|AWZ67145.1|822214_822715_-|7-cyano-7-deazaguanine-reductase
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
>CP030326.1|AWZ66696.1|822734_823601_-|eamA-like-transporter-family-protein
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFFLYKYHQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSSREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFVLFGESPDFYATLGYVVIIGASYYMFEKARRDAKIIKK
>CP030326.1|AWZ67605.1|824401_824800_+|nrdI-protein
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>CP030326.1|AWZ67482.1|824771_826868_+|ribonucleoside-diphosphate-reductase,-alpha-subunit
MEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSISFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
>CP030326.1|AWZ65194.1|826985_827957_+|ribonucleoside-diphosphate-reductase-subunit-beta
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK
>CP030326.1|AWZ66847.1|828331_829303_+|fecCD-transport-family-protein
MKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNILFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFPTGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGLSYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGAIFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ
>CP030326.1|AWZ66606.1|829289_830246_+|fecCD-transport-family-protein
MRNNNKKIMLLIAVTLLISMLYLFVGIDFEIFEYQFSSRLRKFILIILVGAAIATSVVIFQAITNNRLLTPSIMGLDAVYLFIKVLPVFLFGIQSVWVTNVYLNFILTLITMVLFALILFQGIFKIGHFSIYFILLIGVLLGTFFRSITGFIQLIMDPESFLAIQSSMFANFNASNSNLVTFSAVLLVILLVITILLLPYLDVLLLGRAEAINLGISYEKLTRILLVIVSVLVSVSTALVGPITFLGLLTVNLAHELMKTYEHKYILIATICLSWISLFSAQWVVENVFEATTEMSILIDLIGGSYFIYLLVRRRNAQ
>CP030326.1|AWZ67451.1|830242_831004_+|ABC-transporter-family-protein
MIQVENLTKTINNQMILEDISIDIEKGKLTSLIGPNGAGKSTLLSAICRLIRFDNGEVKIDGQLMSDYKNNDLSKKISILKQTNHTEMNITVEQLVNFGRFPYSKGRLTKEDHDIVNDALDLLQLQDIRNRNIKSLSGGQRQRAYIAMTIAQDTEYILLDEPLNNLDMKHAVQIMQTLKMLAHKMNKAIVIVLHDINFASCYSDQIVALKNGQLVKSDLKDNVIQSSVLSDLYDMNIQIEHIRNQRICLYFKD

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Crispr_ID: CP030326_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030326_3

859399-859477

Unclear

Consensus_repeat	Method
TGTAGAATTTCTTTTCGAAATTCT	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of CP030326_3

>merge|CP030326|3|859399-859477|CRISPRCasFinder
TGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCGCCAACTTGCATTGCCTGTAGAATTTCTTTTCGAAATTCT

>CP030326|3|3|859399-859477|CRISPRCasFinder
TGTAGAATTTCTTTTCGAAATTCT	CTGTGTTGGGGCCCCGCCAACTTGCATTGCC
TGTAGAATTTCTTTTCGAAATTCT

Protein	Signature genes	Signature genes Name	Protein_function
CP030326.1\|AWZ65506.1\|865340_866252_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224574
CP030326.1\|AWZ66417.1\|844906_845989_+\|type-III-restriction-enzyme,-res-subunit	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|226583
CP030326.1\|AWZ65667.1\|845981_846656_+\|putative-amidophosphoribosyltransferase,-ComFC	unknown	unknown	gnl\|CDD\|223970
CP030326.1\|AWZ66350.1\|869692_870595_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|224015
CP030326.1\|AWZ66822.1\|853080_853731_+\|HD-containing-hydrolase-like-enzyme-family-protein	unknown	unknown	gnl\|CDD\|378993
CP030326.1\|AWZ67597.1\|853727_853964_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227234
CP030326.1\|AWZ65249.1\|854232_856218_+\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
CP030326.1\|AWZ66773.1\|862013_863453_+\|tetratricopeptide-repeat-family-protein	unknown	unknown	gnl\|CDD\|276808
CP030326.1\|AWZ67086.1\|859735_860668_+\|HPr(Ser)-kinase/phosphatase	unknown	unknown	gnl\|CDD\|235459
CP030326.1\|AWZ66044.1\|867354_868299_+\|sporulation-Regulator-WhiA-C-terminal-domain-protein	unknown	unknown	gnl\|CDD\|273194
CP030326.1\|AWZ67195.1\|850666_851659_+\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
CP030326.1\|AWZ65918.1\|856225_859072_+\|excinuclease-ABC-subunit-A	unknown	unknown	gnl\|CDD\|234734
CP030326.1\|AWZ66921.1\|863519_864455_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
CP030326.1\|AWZ66209.1\|861724_862006_+\|bacterial-transferase-hexapeptide-family-protein	unknown	unknown	gnl\|CDD\|100047
CP030326.1\|AWZ66307.1\|847702_850234_+\|preprotein-translocase,-SecA-subunit	unknown	unknown	gnl\|CDD\|237259
CP030326.1\|AWZ66271.1\|852067_852907_+\|staphyloxanthin-biosynthesis-protein,-putative	unknown	unknown	gnl\|CDD\|226451
CP030326.1\|AWZ65392.1\|868862_869450_+\|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
CP030326.1\|AWZ67694.1\|866248_867244_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|211689
CP030326.1\|AWZ65449.1\|846716_847289_+\|ribosomal-subunit-interface-protein	unknown	unknown	gnl\|CDD\|224461
CP030326.1\|AWZ67374.1\|860673_861513_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527

Protein	Function_ID	Function_description	E-value
CP030326.1\|AWZ65506.1\|865340_866252_+\|hypothetical-protein	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
CP030326.1\|AWZ66417.1\|844906_845989_+\|type-III-restriction-enzyme,-res-subunit	gnl\|CDD\|226583	COG4098, comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair].	1.70203e-180
CP030326.1\|AWZ65667.1\|845981_846656_+\|putative-amidophosphoribosyltransferase,-ComFC	gnl\|CDD\|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	1.0058e-51
CP030326.1\|AWZ66350.1\|869692_870595_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	6.73087e-155
CP030326.1\|AWZ66822.1\|853080_853731_+\|HD-containing-hydrolase-like-enzyme-family-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
CP030326.1\|AWZ67597.1\|853727_853964_+\|hypothetical-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
CP030326.1\|AWZ65249.1\|854232_856218_+\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP030326.1\|AWZ66773.1\|862013_863453_+\|tetratricopeptide-repeat-family-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
CP030326.1\|AWZ67086.1\|859735_860668_+\|HPr(Ser)-kinase/phosphatase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
CP030326.1\|AWZ66044.1\|867354_868299_+\|sporulation-Regulator-WhiA-C-terminal-domain-protein	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
CP030326.1\|AWZ67195.1\|850666_851659_+\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
CP030326.1\|AWZ65918.1\|856225_859072_+\|excinuclease-ABC-subunit-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP030326.1\|AWZ66921.1\|863519_864455_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
CP030326.1\|AWZ66209.1\|861724_862006_+\|bacterial-transferase-hexapeptide-family-protein	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.13458e-26
CP030326.1\|AWZ66307.1\|847702_850234_+\|preprotein-translocase,-SecA-subunit	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
CP030326.1\|AWZ66271.1\|852067_852907_+\|staphyloxanthin-biosynthesis-protein,-putative	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.97111e-42
CP030326.1\|AWZ65392.1\|868862_869450_+\|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
CP030326.1\|AWZ67694.1\|866248_867244_+\|hypothetical-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
CP030326.1\|AWZ65449.1\|846716_847289_+\|ribosomal-subunit-interface-protein	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
CP030326.1\|AWZ67374.1\|860673_861513_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.75588e-120

>CP030326.1|AWZ65918.1|856225_859072_+|excinuclease-ABC-subunit-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>CP030326.1|AWZ65249.1|854232_856218_+|excinuclease-ABC-subunit-B
MVEHYPFKIHSDFEPQGDQPQAIKEIVDGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>CP030326.1|AWZ67597.1|853727_853964_+|hypothetical-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>CP030326.1|AWZ66822.1|853080_853731_+|HD-containing-hydrolase-like-enzyme-family-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>CP030326.1|AWZ66271.1|852067_852907_+|staphyloxanthin-biosynthesis-protein,-putative
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>CP030326.1|AWZ67195.1|850666_851659_+|peptide-chain-release-factor-2
MAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>CP030326.1|AWZ66307.1|847702_850234_+|preprotein-translocase,-SecA-subunit
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>CP030326.1|AWZ65449.1|846716_847289_+|ribosomal-subunit-interface-protein
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>CP030326.1|AWZ65667.1|845981_846656_+|putative-amidophosphoribosyltransferase,-ComFC
MNNCLSCGAKLYENITIYNLFKKPNRLCDRCKENWDNIKLDIKARRCSRCLKHLNQDEAYCLDCKFLSAHFNLMEQLYCQFQYDGLMKEMIHQYKFLKDYYLCELLAHLIEIPQTSYDYIVPIPSSPAHDLSRTFNPVEAVLKAKGIRFDKILKMSNRPKQSHLTKKERLADENPFIIDTELDLNGKEILLVDDIYTTGLTIHRAGCKLYAKNIRKFKVFAFAR
>CP030326.1|AWZ66417.1|844906_845989_+|type-III-restriction-enzyme,-res-subunit
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRMRQTILLYAVTGAGKTEMMFQGIQYARRQGDNIAIVSPRVDVVVEISKRIKDAFLNEDIDILHQQSSQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKSLQQALKSSSKVEHATIYMTATPPKQLLSEIPHENIIKLPARFHKKSLPVPKYRYFKLNNNKIQKMLYRILQDQINNQRYTLVFFNNIETMIKTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKLECPAGKVLFFHEGVSMNMIQAKKEIQRMNKLALKRGWIDE
>CP030326.1|AWZ67086.1|859735_860668_+|HPr(Ser)-kinase/phosphatase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>CP030326.1|AWZ67374.1|860673_861513_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>CP030326.1|AWZ66209.1|861724_862006_+|bacterial-transferase-hexapeptide-family-protein
MLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP030326.1|AWZ66773.1|862013_863453_+|tetratricopeptide-repeat-family-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP030326.1|AWZ66921.1|863519_864455_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>CP030326.1|AWZ65506.1|865340_866252_+|hypothetical-protein
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>CP030326.1|AWZ67694.1|866248_867244_+|hypothetical-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>CP030326.1|AWZ66044.1|867354_868299_+|sporulation-Regulator-WhiA-C-terminal-domain-protein
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>CP030326.1|AWZ65392.1|868862_869450_+|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>CP030326.1|AWZ66350.1|869692_870595_-|NAD-dependent-epimerase/dehydratase-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE

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Crispr_ID: CP030326_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030326_4

864854-865123

Unclear

Consensus_repeat	Method
TTCTCTGTGTTGGGGCCCACACCCCAACTNGCATTG	CRT

4 spacers

The CRISPR arrays of CP030326_4

>merge|CP030326|4|864854-865123|CRT
GCTTCTGTGTTGGGGCCCACACCCCAACTCGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTTTGTTGGGGCCCACACCCCAACTTGCATTGTCTGTAGAAATTGGAAATCCAATTTCTCTGTGTTGGGGCCCACACCCCAACTCGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCACACCCCAACTTGCATTGTCTGTAGAAATTGGAAATCCAATTTCTCTGTGTTGGGGCCCCTGACTAGAGTTGAAAAA

>CP030326|4|1|864854-865123|CRT
GCTTCTGTGTTGGGGCCCACACCCCAACTCGCATTG	CCTGTAGAATTTCTTTTCGAAA
TTCTCTTTGTTGGGGCCCACACCCCAACTTGCATTG	TCTGTAGAAATTGGAAATCCAAT
TTCTCTGTGTTGGGGCCCACACCCCAACTCGCATTG	CCTGTAGAATTTCTTTTCGAAA
TTCTCTGTGTTGGGGCCCACACCCCAACTTGCATTG	TCTGTAGAAATTGGAAATCCAAT
TTCTCTGTGTTGGGGCCCCTGACTAGAGTTGAAAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP030326.1\|AWZ67211.1\|874898_876089_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
CP030326.1\|AWZ65506.1\|865340_866252_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224574
CP030326.1\|AWZ66661.1\|876210_876972_+\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
CP030326.1\|AWZ66350.1\|869692_870595_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|224015
CP030326.1\|AWZ66773.1\|862013_863453_+\|tetratricopeptide-repeat-family-protein	unknown	unknown	gnl\|CDD\|276808
CP030326.1\|AWZ67597.1\|853727_853964_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227234
CP030326.1\|AWZ65249.1\|854232_856218_+\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
CP030326.1\|AWZ66822.1\|853080_853731_+\|HD-containing-hydrolase-like-enzyme-family-protein	unknown	unknown	gnl\|CDD\|378993
CP030326.1\|AWZ65757.1\|871297_871927_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234750
CP030326.1\|AWZ67086.1\|859735_860668_+\|HPr(Ser)-kinase/phosphatase	unknown	unknown	gnl\|CDD\|235459
CP030326.1\|AWZ66044.1\|867354_868299_+\|sporulation-Regulator-WhiA-C-terminal-domain-protein	unknown	unknown	gnl\|CDD\|273194
CP030326.1\|AWZ66446.1\|873749_874760_+\|glyceraldehyde-3-phosphate-dehydrogenase,-type-I	unknown	unknown	gnl\|CDD\|273675
CP030326.1\|AWZ65918.1\|856225_859072_+\|excinuclease-ABC-subunit-A	unknown	unknown	gnl\|CDD\|234734
CP030326.1\|AWZ66921.1\|863519_864455_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
CP030326.1\|AWZ66209.1\|861724_862006_+\|bacterial-transferase-hexapeptide-family-protein	unknown	unknown	gnl\|CDD\|100047
CP030326.1\|AWZ66271.1\|852067_852907_+\|staphyloxanthin-biosynthesis-protein,-putative	unknown	unknown	gnl\|CDD\|226451
CP030326.1\|AWZ65392.1\|868862_869450_+\|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
CP030326.1\|AWZ67694.1\|866248_867244_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|211689
CP030326.1\|AWZ65325.1\|872683_873697_+\|glycolytic-operon-regulator	unknown	unknown	gnl\|CDD\|225263
CP030326.1\|AWZ67374.1\|860673_861513_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527

Protein	Function_ID	Function_description	E-value
CP030326.1\|AWZ67211.1\|874898_876089_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
CP030326.1\|AWZ65506.1\|865340_866252_+\|hypothetical-protein	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
CP030326.1\|AWZ66661.1\|876210_876972_+\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.84083e-146
CP030326.1\|AWZ66350.1\|869692_870595_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	6.73087e-155
CP030326.1\|AWZ66773.1\|862013_863453_+\|tetratricopeptide-repeat-family-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
CP030326.1\|AWZ67597.1\|853727_853964_+\|hypothetical-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
CP030326.1\|AWZ65249.1\|854232_856218_+\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP030326.1\|AWZ66822.1\|853080_853731_+\|HD-containing-hydrolase-like-enzyme-family-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
CP030326.1\|AWZ65757.1\|871297_871927_+\|hypothetical-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.80381e-05
CP030326.1\|AWZ67086.1\|859735_860668_+\|HPr(Ser)-kinase/phosphatase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
CP030326.1\|AWZ66044.1\|867354_868299_+\|sporulation-Regulator-WhiA-C-terminal-domain-protein	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
CP030326.1\|AWZ66446.1\|873749_874760_+\|glyceraldehyde-3-phosphate-dehydrogenase,-type-I	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
CP030326.1\|AWZ65918.1\|856225_859072_+\|excinuclease-ABC-subunit-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP030326.1\|AWZ66921.1\|863519_864455_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
CP030326.1\|AWZ66209.1\|861724_862006_+\|bacterial-transferase-hexapeptide-family-protein	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.13458e-26
CP030326.1\|AWZ66271.1\|852067_852907_+\|staphyloxanthin-biosynthesis-protein,-putative	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.97111e-42
CP030326.1\|AWZ65392.1\|868862_869450_+\|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
CP030326.1\|AWZ67694.1\|866248_867244_+\|hypothetical-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
CP030326.1\|AWZ65325.1\|872683_873697_+\|glycolytic-operon-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92
CP030326.1\|AWZ67374.1\|860673_861513_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.75588e-120

>CP030326.1|AWZ66921.1|863519_864455_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>CP030326.1|AWZ66773.1|862013_863453_+|tetratricopeptide-repeat-family-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP030326.1|AWZ66209.1|861724_862006_+|bacterial-transferase-hexapeptide-family-protein
MLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP030326.1|AWZ67374.1|860673_861513_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>CP030326.1|AWZ67086.1|859735_860668_+|HPr(Ser)-kinase/phosphatase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>CP030326.1|AWZ65918.1|856225_859072_+|excinuclease-ABC-subunit-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>CP030326.1|AWZ65249.1|854232_856218_+|excinuclease-ABC-subunit-B
MVEHYPFKIHSDFEPQGDQPQAIKEIVDGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>CP030326.1|AWZ67597.1|853727_853964_+|hypothetical-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>CP030326.1|AWZ66822.1|853080_853731_+|HD-containing-hydrolase-like-enzyme-family-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>CP030326.1|AWZ66271.1|852067_852907_+|staphyloxanthin-biosynthesis-protein,-putative
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>CP030326.1|AWZ65506.1|865340_866252_+|hypothetical-protein
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>CP030326.1|AWZ67694.1|866248_867244_+|hypothetical-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>CP030326.1|AWZ66044.1|867354_868299_+|sporulation-Regulator-WhiA-C-terminal-domain-protein
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>CP030326.1|AWZ65392.1|868862_869450_+|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>CP030326.1|AWZ66350.1|869692_870595_-|NAD-dependent-epimerase/dehydratase-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>CP030326.1|AWZ65757.1|871297_871927_+|hypothetical-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDNASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>CP030326.1|AWZ65325.1|872683_873697_+|glycolytic-operon-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>CP030326.1|AWZ66446.1|873749_874760_+|glyceraldehyde-3-phosphate-dehydrogenase,-type-I
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>CP030326.1|AWZ67211.1|874898_876089_+|phosphoglycerate-kinase
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>CP030326.1|AWZ66661.1|876210_876972_+|triose-phosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK

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Crispr_ID: CP030326_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030326_5

908081-908162

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP030326_5

>merge|CP030326|5|908081-908162|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGAGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>CP030326|5|4|908081-908162|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGAGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP030326.1\|AWZ65525.1\|904072_904789_+\|3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
CP030326.1\|AWZ65290.1\|904871_905411_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|380312
CP030326.1\|AWZ66180.1\|914211_914973_+\|feS-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
CP030326.1\|AWZ67119.1\|908773_909160_+\|toprim-domain-protein	unknown	unknown	gnl\|CDD\|224572
CP030326.1\|AWZ65099.1\|910758_911412_+\|methionine-import-system-permease-protein-MetP	unknown	unknown	gnl\|CDD\|224922
CP030326.1\|AWZ65656.1\|905561_905882_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
CP030326.1\|AWZ67149.1\|909698_910724_+\|methionine-import-ATP-binding-protein-MetN-2	unknown	unknown	gnl\|CDD\|224058
CP030326.1\|AWZ66796.1\|906983_907097_+\|hypothetical-protein	unknown	unknown	unknown
CP030326.1\|AWZ65751.1\|903502_903925_-\|peroxiredoxin,-Ohr-subfamily-protein	unknown	unknown	gnl\|CDD\|274649
CP030326.1\|AWZ65524.1\|915070_916378_+\|feS-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
CP030326.1\|AWZ65635.1\|911429_912251_+\|NLPA-lipofamily-protein	unknown	unknown	gnl\|CDD\|224381
CP030326.1\|AWZ67699.1\|902609_903104_-\|acetyltransferase-domain-protein	unknown	unknown	gnl\|CDD\|372596
CP030326.1\|AWZ67728.1\|906539_906920_+\|glycine-cleavage-system-H-protein	unknown	unknown	gnl\|CDD\|234918
CP030326.1\|AWZ67094.1\|909152_909449_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
CP030326.1\|AWZ67747.1\|906025_906382_+\|transcriptional-regulator,-Spx/MgsR-family-protein	unknown	unknown	gnl\|CDD\|239334
CP030326.1\|AWZ66602.1\|913032_913884_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224946
CP030326.1\|AWZ65407.1\|901837_902455_-\|lysE-type-translocator-family-protein	unknown	unknown	gnl\|CDD\|224198
CP030326.1\|AWZ65428.1\|916492_917734_+\|putative-cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
CP030326.1\|AWZ66810.1\|912604_912799_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225777
CP030326.1\|AWZ66781.1\|907098_907977_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226395

Protein	Function_ID	Function_description	E-value
CP030326.1\|AWZ65525.1\|904072_904789_+\|3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	3.2619e-146
CP030326.1\|AWZ65290.1\|904871_905411_+\|nitroreductase-family-protein	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
CP030326.1\|AWZ66180.1\|914211_914973_+\|feS-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
CP030326.1\|AWZ67119.1\|908773_909160_+\|toprim-domain-protein	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
CP030326.1\|AWZ65099.1\|910758_911412_+\|methionine-import-system-permease-protein-MetP	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	8.5871e-98
CP030326.1\|AWZ65656.1\|905561_905882_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.4922e-24
CP030326.1\|AWZ67149.1\|909698_910724_+\|methionine-import-ATP-binding-protein-MetN-2	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	2.03316e-170
CP030326.1\|AWZ65751.1\|903502_903925_-\|peroxiredoxin,-Ohr-subfamily-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
CP030326.1\|AWZ65524.1\|915070_916378_+\|feS-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	3.36148e-135
CP030326.1\|AWZ65635.1\|911429_912251_+\|NLPA-lipofamily-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	1.02861e-112
CP030326.1\|AWZ67699.1\|902609_903104_-\|acetyltransferase-domain-protein	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	1.02873e-46
CP030326.1\|AWZ67728.1\|906539_906920_+\|glycine-cleavage-system-H-protein	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	9.01516e-70
CP030326.1\|AWZ67094.1\|909152_909449_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
CP030326.1\|AWZ67747.1\|906025_906382_+\|transcriptional-regulator,-Spx/MgsR-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
CP030326.1\|AWZ66602.1\|913032_913884_-\|hypothetical-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	7.67366e-77
CP030326.1\|AWZ65407.1\|901837_902455_-\|lysE-type-translocator-family-protein	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	2.60719e-61
CP030326.1\|AWZ65428.1\|916492_917734_+\|putative-cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
CP030326.1\|AWZ66810.1\|912604_912799_+\|hypothetical-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
CP030326.1\|AWZ66781.1\|907098_907977_+\|hypothetical-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	3.13065e-77

>CP030326.1|AWZ66781.1|907098_907977_+|hypothetical-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLSQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLNDLPEQQELFPVNEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQVHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>CP030326.1|AWZ66796.1|906983_907097_+|hypothetical-protein
MKENLLGTIIWSIATFYYSRMMKIMNLAILKIKIGGS
>CP030326.1|AWZ67728.1|906539_906920_+|glycine-cleavage-system-H-protein
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQLEALLTAEKYSEMIGE
>CP030326.1|AWZ67747.1|906025_906382_+|transcriptional-regulator,-Spx/MgsR-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>CP030326.1|AWZ65656.1|905561_905882_-|thioredoxin-family-protein
MQAIKSNESFKSIINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>CP030326.1|AWZ65290.1|904871_905411_+|nitroreductase-family-protein
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>CP030326.1|AWZ65525.1|904072_904789_+|3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFINDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIIKHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>CP030326.1|AWZ65751.1|903502_903925_-|peroxiredoxin,-Ohr-subfamily-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>CP030326.1|AWZ67699.1|902609_903104_-|acetyltransferase-domain-protein
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNAYFDEHWLFYDLINK
>CP030326.1|AWZ65407.1|901837_902455_-|lysE-type-translocator-family-protein
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQIISPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF
>CP030326.1|AWZ67119.1|908773_909160_+|toprim-domain-protein
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>CP030326.1|AWZ67094.1|909152_909449_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>CP030326.1|AWZ67149.1|909698_910724_+|methionine-import-ATP-binding-protein-MetN-2
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEHGPVTQVFENPQHTVTKRFVKEDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>CP030326.1|AWZ65099.1|910758_911412_+|methionine-import-system-permease-protein-MetP
MPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWIVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>CP030326.1|AWZ65635.1|911429_912251_+|NLPA-lipofamily-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYDLDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>CP030326.1|AWZ66810.1|912604_912799_+|hypothetical-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>CP030326.1|AWZ66602.1|913032_913884_-|hypothetical-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTGLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFTGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>CP030326.1|AWZ66180.1|914211_914973_+|feS-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>CP030326.1|AWZ65524.1|915070_916378_+|feS-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKHFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDKNASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>CP030326.1|AWZ65428.1|916492_917734_+|putative-cysteine-desulfurase
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPMQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF

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Crispr_ID: CP030326_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030326_6

1742606-1742690

Orphan

Consensus_repeat	Method
CACCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP030326_6

>merge|CP030326|6|1742606-1742690|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTGTGTTGGGGCCCACACCCCAACTTGCATTGCCTGTAGAA

>CP030326|6|5|1742606-1742690|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTGTGTTGGGGCCCA
CACCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP030326.1\|AWZ66088.1\|1750916_1751501_-\|HD-domain-protein	unknown	unknown	gnl\|CDD\|224627
CP030326.1\|AWZ66524.1\|1746358_1748560_-\|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl\|CDD\|225212
CP030326.1\|AWZ65591.1\|1745031_1745283_+\|ribosomal-protein-S20	unknown	unknown	gnl\|CDD\|178943
CP030326.1\|AWZ65432.1\|1732742_1732919_-\|ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
CP030326.1\|AWZ65625.1\|1739436_1740063_-\|protein-GrpE	unknown	unknown	gnl\|CDD\|237622
CP030326.1\|AWZ67741.1\|1741172_1742297_-\|radical-SAM-superfamily-protein	unknown	unknown	gnl\|CDD\|236309
CP030326.1\|AWZ66092.1\|1750562_1750916_-\|ribosomal-silencing-factor-RsfS	unknown	unknown	gnl\|CDD\|223870
CP030326.1\|AWZ67281.1\|1735318_1736257_-\|ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|283886
CP030326.1\|AWZ65481.1\|1745327_1746302_-\|DNA-polymerase-III,-delta-subunit	unknown	unknown	gnl\|CDD\|235511
CP030326.1\|AWZ66521.1\|1734564_1735317_-\|ribosomal-RNA-small-subunit-methyltransferase-E	unknown	unknown	gnl\|CDD\|224303
CP030326.1\|AWZ67577.1\|1742862_1744686_-\|GTP-binding-protein-LepA	unknown	unknown	gnl\|CDD\|235462
CP030326.1\|AWZ65968.1\|1740094_1741072_-\|heat-inducible-transcription-repressor-HrcA	unknown	unknown	gnl\|CDD\|273017
CP030326.1\|AWZ66324.1\|1733211_1734558_-\|threonylcarbamoyladenosine-tRNA-methylthiotransferase-MtaB	unknown	unknown	gnl\|CDD\|223694
CP030326.1\|AWZ65694.1\|1749117_1749795_-\|competence-ComEA-helix-hairpin-helix-repeat-region-domain-protein	unknown	unknown	gnl\|CDD\|224472
CP030326.1\|AWZ67263.1\|1751490_1752060_-\|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase	unknown	unknown	gnl\|CDD\|273101
CP030326.1\|AWZ66328.1\|1737535_1739368_-\|chaperone-protein-DnaK	unknown	unknown	gnl\|CDD\|234715
CP030326.1\|AWZ66714.1\|1731815_1732499_-\|putative-membrane-bound-serine-protease	unknown	unknown	gnl\|CDD\|223961
CP030326.1\|AWZ67053.1\|1748564_1749026_-\|comE-operon-protein-2	unknown	unknown	gnl\|CDD\|131622
CP030326.1\|AWZ67578.1\|1749843_1750560_-\|methyltransferase-type-12	unknown	unknown	gnl\|CDD\|379312
CP030326.1\|AWZ67064.1\|1736260_1737400_-\|chaperone-protein-DnaJ	unknown	unknown	gnl\|CDD\|237656

Protein	Function_ID	Function_description	E-value
CP030326.1\|AWZ66088.1\|1750916_1751501_-\|HD-domain-protein	gnl\|CDD\|224627	COG1713, COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism].	2.21948e-80
CP030326.1\|AWZ66524.1\|1746358_1748560_-\|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl\|CDD\|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	3.64233e-90
CP030326.1\|AWZ65591.1\|1745031_1745283_+\|ribosomal-protein-S20	gnl\|CDD\|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	1.42889e-17
CP030326.1\|AWZ65432.1\|1732742_1732919_-\|ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	1.15423e-10
CP030326.1\|AWZ65625.1\|1739436_1740063_-\|protein-GrpE	gnl\|CDD\|237622	PRK14140, PRK14140, heat shock protein GrpE; Provisional.	3.74407e-81
CP030326.1\|AWZ67741.1\|1741172_1742297_-\|radical-SAM-superfamily-protein	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
CP030326.1\|AWZ66092.1\|1750562_1750916_-\|ribosomal-silencing-factor-RsfS	gnl\|CDD\|223870	COG0799, COG0799, Uncharacterized homolog of plant Iojap protein [Function unknown].	5.95861e-47
CP030326.1\|AWZ67281.1\|1735318_1736257_-\|ribosomal-protein-L11-methyltransferase	gnl\|CDD\|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	9.7051e-134
CP030326.1\|AWZ65481.1\|1745327_1746302_-\|DNA-polymerase-III,-delta-subunit	gnl\|CDD\|235511	PRK05574, holA, DNA polymerase III subunit delta; Reviewed.	4.1415e-104
CP030326.1\|AWZ66521.1\|1734564_1735317_-\|ribosomal-RNA-small-subunit-methyltransferase-E	gnl\|CDD\|224303	COG1385, COG1385, Uncharacterized protein conserved in bacteria [Function unknown].	1.90273e-91
CP030326.1\|AWZ67577.1\|1742862_1744686_-\|GTP-binding-protein-LepA	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
CP030326.1\|AWZ65968.1\|1740094_1741072_-\|heat-inducible-transcription-repressor-HrcA	gnl\|CDD\|273017	TIGR00331, Heat-inducible_transcription_repressor_HrcA, heat shock gene repressor HrcA. HrcA represses the class I heat shock operons groE and dnaK; overproduction prevents induction of these operons by heat shock while deletion allows constitutive expression even at low temperatures. In Bacillus subtilis, hrcA is the first gene of the dnaK operon and so is itself a heat shock gene. [Regulatory functions, DNA interactions].	2.05887e-119
CP030326.1\|AWZ66324.1\|1733211_1734558_-\|threonylcarbamoyladenosine-tRNA-methylthiotransferase-MtaB	gnl\|CDD\|223694	COG0621, MiaB, 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis].	0
CP030326.1\|AWZ65694.1\|1749117_1749795_-\|competence-ComEA-helix-hairpin-helix-repeat-region-domain-protein	gnl\|CDD\|224472	COG1555, ComEA, DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair].	8.07958e-34
CP030326.1\|AWZ67263.1\|1751490_1752060_-\|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase	gnl\|CDD\|273101	TIGR00482, Probable_nicotinate-nucleotide_adenylyltransferase, nicotinate (nicotinamide) nucleotide adenylyltransferase. This model represents the predominant bacterial/eukaryotic adenylyltransferase for nicotinamide-nucleotide, its deamido form nicotinate nucleotide, or both. The first activity, nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1), synthesizes NAD by the salvage pathway, while the second, nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) synthesizes the immediate precursor of NAD by the de novo pathway. In E. coli, NadD activity is biased toward the de novo pathway while salvage activity is channeled through the multifunctional NadR protein, but this division of labor may be exceptional. The given name of this model, nicotinate (nicotinamide) nucleotide adenylyltransferase, reflects the lack of absolute specificity with respect to substrate amidation state in most species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides].	2.64141e-76
CP030326.1\|AWZ66328.1\|1737535_1739368_-\|chaperone-protein-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
CP030326.1\|AWZ66714.1\|1731815_1732499_-\|putative-membrane-bound-serine-protease	gnl\|CDD\|223961	COG1030, NfeD, Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones].	8.78003e-63
CP030326.1\|AWZ67053.1\|1748564_1749026_-\|comE-operon-protein-2	gnl\|CDD\|131622	TIGR02571, putative_dCMP_deaminase, ComE operon protein 2. This protein is found in the ComE operon for "late competence" as characterized in B. subtilis. Proteins in this family contain homology to a cytidine/deoxycytidine deaminase domain family (pfam00383), and may carry out this activity.	4.81051e-102
CP030326.1\|AWZ67578.1\|1749843_1750560_-\|methyltransferase-type-12	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	7.79783e-16
CP030326.1\|AWZ67064.1\|1736260_1737400_-\|chaperone-protein-DnaJ	gnl\|CDD\|237656	PRK14280, PRK14280, molecular chaperone DnaJ.	0

>CP030326.1|AWZ67741.1|1741172_1742297_-|radical-SAM-superfamily-protein
MTVQSAYIHIPFCVRICTYCDFNKYFIQNQPVDEYLDALITEMSTAKYRNLKTMYVGGGTPTALSINQLERLLKAIRDTFTITGEYTFEANPDELTKEKVQLLEKYGVNRISMGVQTFKPELLSVLGRTHNTEDIYTSVLNAKNAGIKSISLDLMYHLPKQTIEDFEQSLDLALDMDIQHISSYGLILEPKTQFYNMYRKGLLKLPNEDLGADMYQLLMSKIEQSPFHQYEISNFALDGHESEHNKVYWFNEEYYGFGAGASGYVDGVRYTNINPVNHYIKAINKESKAILVSNKPSLTERMEEEMFLGLRLNEGVSSSRFKKKFDQSIESVFGQTINNLKEKELIVEKNDAIALTKRGKVIGNEVFEAFLIND
>CP030326.1|AWZ65968.1|1740094_1741072_-|heat-inducible-transcription-repressor-HrcA
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW
>CP030326.1|AWZ65625.1|1739436_1740063_-|protein-GrpE
MTNKDESVEKNTESTVEETNIKQNIDDSVEQAEESKGHLQDEAIEETSDENVIEEIDPKDQKINELQQLADENEEKYLRLYAEFENYKRRIQKENEINKTYQAQRVLTDILPAIDNIERALQIEGDDETFKSLQKGVQMVHESLINALKDNGLEVIKTEGEAFDPNIHQAVVQDDNPDFESGEITQELQKGYKLKDRVLRPSMVKVNQ
>CP030326.1|AWZ66328.1|1737535_1739368_-|chaperone-protein-DnaK
MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAESYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKDEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFEELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSKSQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDKNGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNEADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFKEVKDDDKK
>CP030326.1|AWZ67064.1|1736260_1737400_-|chaperone-protein-DnaJ
MAKRDYYEVLGISKDASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDDNKRASYDQFGHDGPQGFGGQGFNGSDFGGFSGFGGGGFEDIFSSFFGGGRQRDPNAPQKGDDLQYTMTLTFEEAVFGTTKEISIRKDVTCETCHGDGAKPGTSKKTCSYCNGAGHVAVEQNTILGRVRTEQVCPKCNGSGQEFEEACPTCHGKGTENKTVKLEVKVPEGVDNEQQIRLAGEGSPGVNGGPAGDLYVVFRVKPSETFKRDGDDIYYKLNVSFPQAALGDEIKIPTLNNEVMLTIPAGTQTGKQFRLKEKGIKNVHGYGYGDLYVDIKVVTPTKLTDRQKELMKEFAQLNGEEINEQPSNFKDRAKRFFKGE
>CP030326.1|AWZ67281.1|1735318_1736257_-|ribosomal-protein-L11-methyltransferase
MNWTELSIIINHEAVELATNILENHGSNGVVIEDSDDLINQPEDKYGEIYALKKEDYPDKGVRLKAYFNEMTYDDKLRQQIKDELLNLDELDQHNIQFSEQIIAETDWENEWKNYFHPFRASKKFTIVPSWETYAKEADEELCIELDPGMAFGTGDHPTTSMCLKAIETYVLPQHSVIDVGTGSGILSIASHLIGVKRIKALDIDEMAVSVAKENFRRNHCETLIEAVPGNLLKDETEKFDIVIANILAHIIDEMIEDAYNTLNEGGYFITSGIIKEKYEGIQSHMERVGFKIISEQHDNGWVCLVGQKVSE
>CP030326.1|AWZ66521.1|1734564_1735317_-|ribosomal-RNA-small-subunit-methyltransferase-E
MQRYFIDQNADVSQRFFITKKEDIHHITNVMRYDVGSKIILTFNDQTVYLCEIADITSDKIAVDLKEKQNINTELPVDVTICSGLIKADKYEWLLQKATELGASSFIAVSMERSIVKLNEAKVVKKIERWQKIIKEAAEQSYRLVIPSIQFESNLKLICDTIDNYDYILIAYEEEAKDGELSNFKQTLQQFKAQDKVLMIFGPEGGLSENEISLFSNTSTVVGLGPRILRAETAPLYALSAISYEKELMG
>CP030326.1|AWZ66324.1|1733211_1734558_-|threonylcarbamoyladenosine-tRNA-methylthiotransferase-MtaB
MSTVAFHTLGCKVNHYETEAIWQLFKEANYERVDFEANADVFVINTCTVTNTGDKKSRQIIRRAIRQNPDAVICVTGCYAQTSSAEIMEIPGVDVVVGTQDRHKLLGYIDEFRKERQPINGVGNIMKNRKYEELDVPYFTDRTRASLKIQEGCNNFCTFCIIPWARGLMRSRDPEKVVEQATQLVNSGYKEIVLTGIHTGGYGQDLKDYNLAQLLRDLETINGLERIRISSIEASQLTDEVIDVLERSTKVVRHLHIPLQSGSDTVLKRMRRKYTMDRFSERLTKLHKALPDLAVTSDVIVGFPGETEAEFQETYDFIVKHKFSELHVFPYSPRIGTPAARMDDQIDEEIKNERVHKLITLSNQLGKLYASKFDQDVLEVIPEEQGDTEGTLVGYADNYMKVQFEGDESLIGQIVKVKITQANYPLNEGQAIKVVDFATNKSDREVLV
>CP030326.1|AWZ65432.1|1732742_1732919_-|ribosomal-protein-S21
MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
>CP030326.1|AWZ66714.1|1731815_1732499_-|putative-membrane-bound-serine-protease
MTTILESTAGDTWVEQVSNIIVQPIFTLILTCLTFLGFVYQLYSKKINAAGIIATLSLLILFLGFLIQGNVNMHSILIFSIGVILVVIELFVVGAVIGIIGMILITISITTLGDNLLFMLANVIVALILTIVEWVILVKIFNRKIPFLDKVILKDSTNSESGYNSHDNRSHLVGKTAQTVTDLRPAGIIFCENERIDAVSDGNFILRNKTVKILEVEGTRVVVREVD
>CP030326.1|AWZ67577.1|1742862_1744686_-|GTP-binding-protein-LepA
MDNEQRLKRRENIRNFSIIAHIDHGKSTLADRILENTKSVETRDMQDQLLDSMDLERERGITIKLNAVRLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNELELLPVINKIDLPAAEPERVKQEIEDMIGLDQDDVVLASAKSNIGIEEILEKIVEVVPAPDGDPEAPLKALIFDSEYDPYRGVISSIRIVDGVVKAGDKIRMMATGKEFEVTEVGINTPKQLPVDELTVGDVGYIIASIKNVDDSRVGDTITLASRPASEPLQGYKKMNPMVYCGLFPIDNKNYNDLREALEKLQLNDASLEFEPESSQALGFGYRTGFLGMLHMEIIQERIEREFGIELIATAPSVIYQCILRDGSEVTVDNPAQMPDRDKIDKIFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVNIVYELPLAEVVFDFFDQLKSNTKGYASFDYEFIENKESNLVKMDILLNGDKVDALSFIVHRDFAYERGKALVEKLKTLIPRQQFEVPVQAAIGQKIVARTNIKSMGKNVLAKCYGGDISRKRKLLEKQKAGKAKMKAVGNVEIPQDAFLAVLKMDDE
>CP030326.1|AWZ65591.1|1745031_1745283_+|ribosomal-protein-S20
MANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAVSNNADNKNELVSLAVKLVDKAAQSNLIHSNKADRIKSQLMTANK
>CP030326.1|AWZ65481.1|1745327_1746302_-|DNA-polymerase-III,-delta-subunit
MSDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYETEIAPIVEETLTLPFFSDKKAILVKNAYIFTGEKAPKDMAHNVDQLIEFIEKYDGENLIVFEIYQNKLDERKKLTKTLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALDLFIELTGINFNIVSQEIEKLILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRKKEQAIHLVKDLITMKEEPIKLLALITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYRVKLALGQVRHYQLDELLNIVDACAETDYKLKSSYMDKQLILELFILSL
>CP030326.1|AWZ66524.1|1746358_1748560_-|DNA-internalization-related-competence-protein-ComEC/Rec2
MLYVALSMIVGVLWNSSKVLSTFLFILLLYITYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNSQFNERAQVIQIQRQGSDTYKGRLSLKNEIYPFFLTDKKNFDLKKIESRNCIVKGQFKVNENKFVTLKLQSIVVQSCLESNRSNLIEKHKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGITIIVLTLYAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQQLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYLVDLSFNFHDWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSILYEGGKNQNVLIDTGGKVIDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKGYSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLLKKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNLKVDSNSYGNASGL
>CP030326.1|AWZ67053.1|1748564_1749026_-|comE-operon-protein-2
MERIKWEEYFMAQSHLLALRSTCQRLSVGATIVKDNRIIAGGYNGSVAGEVHCIDEGCLIEDGHCIRTIHAEMNALLQCAKQGVSTEGATIYVTHFPCLNCTKSIIQAGIKRIYYAEDYHNHEYATKLLKQSGIEFKKIPFSPEYVAKYLTKG
>CP030326.1|AWZ65694.1|1749117_1749795_-|competence-ComEA-helix-hairpin-helix-repeat-region-domain-protein
MYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSKNKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKNGNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI
>CP030326.1|AWZ67578.1|1749843_1750560_-|methyltransferase-type-12
MSQYAEMSLVYDQLTQDQPYEKWFEIVKNHCKDESNILDIGCGTGSLTVQLEALGNVTGMDLSVDMLTVAAQKSANVNWLEGDMTSFDLQQQFDIITIFCDSLNYLQDETAVIETFINVYHHLTDSGVFIFDVHTVYKMMTLFNNQSYIDDKGDIFLAWDAVQGDLPLSVYHDMTFFIRHEDETYSRFDESHFQRTFDEKTYLSWLAQVGFKHVETFTDFNIDEHNEDTERLFFIAKK
>CP030326.1|AWZ66092.1|1750562_1750916_-|ribosomal-silencing-factor-RsfS
MNSQELLAIAVDAIDNKKGEDTISLEMKGISDMTDYFVVTHGNNERQVQAIARAVKEVANEQNIEVKRMEGYNEARWILIDLADVVVHVFHKDERNYYNIEKLYQDAPLESYGQVAY
>CP030326.1|AWZ66088.1|1750916_1751501_-|HD-domain-protein
MNIEKAKRLAKEKLPEKRYNHSLRVAETAIKLAEIYDGDTSKVELAGVLHDFCKYDDLGKMYQIVRQYELGNDLLSYGSEILHGPVCAAIMEHEYGINDEEVLMAIKYHTTGRQQMTKTEKLIFIADYIEPGRTIPGVDDIRDMAYNQGSLDKTIYEISKRTVLFLIQKDITVYNKTIDCLNYYNYSDERIKDD
>CP030326.1|AWZ67263.1|1751490_1752060_-|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH

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Crispr_ID: CP030326_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030326_7

2175847-2175928

Orphan

Consensus_repeat	Method
GGCCCCCACCCCAACTTACATTGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP030326_7

>merge|CP030326|7|2175847-2175928|CRISPRCasFinder
GGCCCCCACCCCAACTTACATTGTTTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCCACCCCAACTTGCATTGT

>CP030326|7|6|2175847-2175928|CRISPRCasFinder
GGCCCCCACCCCAACTTACATTGT	TTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGG
GGCCCCCACCCCAACTTGCATTGT

Protein	Signature genes	Signature genes Name	Protein_function
CP030326.1\|AWZ66511.1\|2168552_2168735_+\|hypothetical-protein	unknown	unknown	unknown
CP030326.1\|AWZ65795.1\|2183278_2184064_+\|hydrolase,-carbon-nitrogen-family	unknown	unknown	gnl\|CDD\|143607
CP030326.1\|AWZ65450.1\|2179608_2179893_-\|10-kDa-chaperonin	unknown	unknown	gnl\|CDD\|178988
CP030326.1\|AWZ65241.1\|2172911_2173967_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369625
CP030326.1\|AWZ65224.1\|2185599_2185743_+\|cyclic-lactone-autoinducer-peptide-family-protein	unknown	unknown	gnl\|CDD\|129030
CP030326.1\|AWZ66316.1\|2171873_2172890_-\|gamma-hemolysin-component-B	unknown	unknown	gnl\|CDD\|369625
CP030326.1\|AWZ67407.1\|2176069_2177377_+\|ktr-system-potassium-uptake-protein-B	unknown	unknown	gnl\|CDD\|273349
CP030326.1\|AWZ67315.1\|2168813_2169527_+\|pemK-like-family-protein	unknown	unknown	gnl\|CDD\|367091
CP030326.1\|AWZ66072.1\|2184663_2184798_-\|delta-hemolysin-domain-protein	unknown	unknown	gnl\|CDD\|173213
CP030326.1\|AWZ67545.1\|2180835_2182095_-\|putative-sdrH-protein	unknown	unknown	gnl\|CDD\|236768
CP030326.1\|AWZ66265.1\|2168153_2168300_+\|hypothetical-protein	unknown	unknown	unknown
CP030326.1\|AWZ66527.1\|2170811_2171636_+\|sphingomyelin-phosphodiesterase	unknown	unknown	gnl\|CDD\|132436
CP030326.1\|AWZ65886.1\|2174402_2175626_+\|putative-succinyl-diaminopimelate-desuccinylase	unknown	unknown	gnl\|CDD\|181490
CP030326.1\|AWZ67236.1\|2177916_2179533_-\|chaperonin-GroL	unknown	unknown	gnl\|CDD\|234573
CP030326.1\|AWZ66149.1\|2168296_2168482_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376389
CP030326.1\|AWZ65196.1\|2182291_2182918_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
CP030326.1\|AWZ65178.1\|2180067_2180811_+\|CAAX-protease-self-immunity-family-protein	unknown	unknown	gnl\|CDD\|376806
CP030326.1\|AWZ65700.1\|2167225_2168080_+\|HIRAN-domain-protein	unknown	unknown	gnl\|CDD\|214906
CP030326.1\|AWZ65207.1\|2169717_2170755_+\|integrase	unknown	unknown	gnl\|CDD\|271189
CP030326.1\|AWZ66046.1\|2184979_2185597_+\|accessory-gene-regulator-protein-B	unknown	unknown	gnl\|CDD\|226899

Protein	Function_ID	Function_description	E-value
CP030326.1\|AWZ65795.1\|2183278_2184064_+\|hydrolase,-carbon-nitrogen-family	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	5.69545e-126
CP030326.1\|AWZ67236.1\|2177916_2179533_-\|chaperonin-GroL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
CP030326.1\|AWZ65241.1\|2172911_2173967_-\|hypothetical-protein	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	1.84035e-77
CP030326.1\|AWZ65224.1\|2185599_2185743_+\|cyclic-lactone-autoinducer-peptide-family-protein	gnl\|CDD\|129030	smart00794, AgrD, Staphylococcal AgrD protein. This family consists of several AgrD proteins from many Staphylococcus species. The agr locus was initially described in Staphylococcus aureus as an element controlling the production of exoproteins implicated in virulence. Its pattern of action has been shown to be complex, upregulating certain extracellular toxins and enzymes expressed post-exponentially and repressing some exponential-phase surface components. AgrD encodes the precursor of the autoinducing peptide (AIP).The AIP derived from AgrD by the action of AgrB interacts with AgrC in the membrane to activate AgrA, which upregulates transcription both from promoter P2, amplifying the response, and from P3, initiating the production of a novel effector: RNAIII. In S. aureus, delta-hemolysin is the only translation product of RNA III and is not involved in the regulatory functions of the transcript, which is therefore the primary agent for modulating the expression of other operons controlled by agr.	3.13559e-15
CP030326.1\|AWZ66316.1\|2171873_2172890_-\|gamma-hemolysin-component-B	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	1.05827e-99
CP030326.1\|AWZ67407.1\|2176069_2177377_+\|ktr-system-potassium-uptake-protein-B	gnl\|CDD\|273349	TIGR00933, Trk_system_potassium_uptake_protein_trkH., potassium uptake protein, TrkH family. The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds].	7.96864e-82
CP030326.1\|AWZ67315.1\|2168813_2169527_+\|pemK-like-family-protein	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	0.000176738
CP030326.1\|AWZ66072.1\|2184663_2184798_-\|delta-hemolysin-domain-protein	gnl\|CDD\|173213	PRK14752, PRK14752, delta-lysin family phenol-soluble modulin.	8.25732e-15
CP030326.1\|AWZ67545.1\|2180835_2182095_-\|putative-sdrH-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	6.51148e-10
CP030326.1\|AWZ66527.1\|2170811_2171636_+\|sphingomyelin-phosphodiesterase	gnl\|CDD\|132436	TIGR03395, Sphingomyelinase_C, sphingomyelin phosphodiesterase. Members of this family are bacterial proteins that act as sphingomyelin phosphodiesterase (EC 3.1.4.12), also called sphingomyelinase. Some members of this family have been shown to act as hemolysins. [Cellular processes, Pathogenesis].	4.43323e-127
CP030326.1\|AWZ65886.1\|2174402_2175626_+\|putative-succinyl-diaminopimelate-desuccinylase	gnl\|CDD\|181490	PRK08588, PRK08588, succinyl-diaminopimelate desuccinylase; Reviewed.	0
CP030326.1\|AWZ65450.1\|2179608_2179893_-\|10-kDa-chaperonin	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	5.94304e-45
CP030326.1\|AWZ66149.1\|2168296_2168482_+\|hypothetical-protein	gnl\|CDD\|376389	pfam00815, Histidinol_dh, Histidinol dehydrogenase.	0.00485103
CP030326.1\|AWZ65196.1\|2182291_2182918_+\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	8.42197e-117
CP030326.1\|AWZ65178.1\|2180067_2180811_+\|CAAX-protease-self-immunity-family-protein	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.68223e-11
CP030326.1\|AWZ65700.1\|2167225_2168080_+\|HIRAN-domain-protein	gnl\|CDD\|214906	smart00910, HIRAN, The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. HIRAN is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, such as a nuclease of the restriction endonuclease fold and TDP1-like DNA phosphoesterases, in the eukaryotes. It has been predicted that this protein functions as a DNA-binding domain that probably recognises features associated with damaged DNA or stalled replication forks.	5.87951e-12
CP030326.1\|AWZ65207.1\|2169717_2170755_+\|integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.96401e-25
CP030326.1\|AWZ66046.1\|2184979_2185597_+\|accessory-gene-regulator-protein-B	gnl\|CDD\|226899	COG4512, AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide [Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription].	9.73444e-74

>CP030326.1|AWZ65886.1|2174402_2175626_+|putative-succinyl-diaminopimelate-desuccinylase
MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGNQDNWTYPPFQLTEKAGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGLIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGKEISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEASIQYLKEK
>CP030326.1|AWZ65241.1|2172911_2173967_-|hypothetical-protein
MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKDKRNVTNKDKNSTVPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKEG
>CP030326.1|AWZ66316.1|2171873_2172890_-|gamma-hemolysin-component-B
MIKQLYKNITICSLAISTALTVFPATSYAKINSEIKAVSEKNLDGDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDFSINRGGLTGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDKGKSQFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHDVKFVKVLNDNEKK
>CP030326.1|AWZ66527.1|2170811_2171636_+|sphingomyelin-phosphodiesterase
MYPNWGQYKRADLIGQSSYIKNNDVVIFNEAFDNGASDKLLSNVKKEYPYQTPVLGRSQSGWDKTEGSYSSTVAEDGGVAIVSKYPIKEKIQHVFKSGCGFDNDSNKGFVYTKIEKNGKNIHVIGTHTQSEDSRCGAGHDRKIRAEQMKEISDFVKKKNIPKDETVYIGGDLNVNKGTPEFKDMLKNLNVNDVLYAGHNSTWDPQSNSIAKYNYPNGKPEHLDYIFTDKDHKQPKQLVNEVVTEKPKPWDVYAFPYYYVYNDFSDHYPIKAYSK
>CP030326.1|AWZ65207.1|2169717_2170755_+|integrase
MKTRCYDGKKWQYEFKYEGKRYRKKGFRTKREANSAGLDKLNELRSGFNIDNYITLEEYFENWIKTYKQPVVKENTYRHYRNALQHIQKHKIGKMELSKINRQVYQKFINDYSKEHAKETIRKTNGAIRSALDDALYDGLIFKNPAYKVNYKAGKPTKSEQEKFISVTEYEILKDHVRKKRTRSSLALFIMICTGCRVSGARNIKIEHINQVKNTIFIDERKTDTSPRYISIAKSDMKHIMDVISTFAISYDGYIFKEAGSIINLQAINNALKSACRVNNIPIITSHALRHTHCSYLLAKGVSIHYISKRLGHKNIAITTSVYSHLLEEKFNEEDKKTTKILESM
>CP030326.1|AWZ67315.1|2168813_2169527_+|pemK-like-family-protein
MTHNIEKRINKLKTSGNPKFKKLDSDIHYLLKRFEGEKNHKGFYPKFKQGEIVFVDFGINVNKEFSNSHFAIVMNKNDSNTEDIVNVIPLSSKENKKYLKMNFDLKWEYYLRLFLNLISAQNNSAILKEVFDKKYQKNNTEFITKDYFSEFISDSLEIENKLNKIDRNINNIVSAIDKVKKLKGNSYACINSFQPISKFRIRKVLPQKIKNPVIDSSDIMLLINRINNNILQIPDIR
>CP030326.1|AWZ66511.1|2168552_2168735_+|hypothetical-protein
MKITNCKIKRETIVYEVLTSGNQPFTYELPKDLSSHNARKYLEFISQKIDGDKLTKEDSL
>CP030326.1|AWZ66149.1|2168296_2168482_+|hypothetical-protein
MSTYKEIEHLHINTGGKELTQEQIEEAKAFIDSQEFKDMIREAKESHQRVMESKITDRTKL
>CP030326.1|AWZ66265.1|2168153_2168300_+|hypothetical-protein
MDFKEVDINIEEWEMVEIPFYTEEELTYRLNNGLPITKSELEEQESKK
>CP030326.1|AWZ65700.1|2167225_2168080_+|HIRAN-domain-protein
MKPRKQDEKILSDQYSYFEPIISDSCDIKFDENKRRMGSIFISHEEICFIRKEEDYIFKISLSEVIDYNTVVTIWKNQAFLTLNDNRKLTVYFVTNSPLTGFISILKTYMQLSKNKETIISNDCLPINDDEQTKVEIFDVVGLNYEGRRKELKKLIKKMKNNDDFFFLYSDLKGNELKEELLYEDKVYEISDYEVIPGVFLQKEPDNPYDENAIKVMISNEYSEFHVGYVPREYASRLVNHMDNIVSCNAYINGGKYKTLDYLEEKIVTKESDYGLRVHLEYKV
>CP030326.1|AWZ67407.1|2176069_2177377_+|ktr-system-potassium-uptake-protein-B
MNKVHKPLYFYLMLFFSTTIIGALLLYLPFTGKKPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKISMKNRFLIMVTWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSFIPKFGIGKGLFLSLFTSVSAFNNAGFALFKNNLIDYSSDPIVIITISILIIFGGIGHFVVIDFINCKKLSKLSLHSKLVLTTTSILIIIGAITFFLLEQFNTMQHMGLVEKIGNSFFQSVTTRTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRKENNVSVFNKEISDKHIKLSIVTINISFLFISIITFILSIINPNISLIKLLFEVVSAFGTVGLSMNLTTEYHGITKIIIIFVMLCGKVGLLTLLRTFIPPKSPKNYRYTKGQIYL
>CP030326.1|AWZ67236.1|2177916_2179533_-|chaperonin-GroL
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>CP030326.1|AWZ65450.1|2179608_2179893_-|10-kDa-chaperonin
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>CP030326.1|AWZ65178.1|2180067_2180811_+|CAAX-protease-self-immunity-family-protein
MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVASIVLTQIYGGQQVSPNTEKLIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGNRIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>CP030326.1|AWZ67545.1|2180835_2182095_-|putative-sdrH-protein
MSYHWFKKMLLSTSILILSSSSLGLATHTVEAKDNLNGEKPTTNLNHNITSPSVNSEMNNNETGTPHESNQTGNEGTGSNSRDANPDSNNVKPDSNNQNPSTDSKPDPNNQNPSPNPKPDPDNPKPKPDPKPDPDKPKPNLDPKPDPDNPKPKPDPKPDPDKPKPNPDPKPDPDKPKPNPNPKPDPNKPNPNPSPDPDQPGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>CP030326.1|AWZ65196.1|2182291_2182918_+|nitroreductase-family-protein
MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSKEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK
>CP030326.1|AWZ65795.1|2183278_2184064_+|hydrolase,-carbon-nitrogen-family
MKVQIYQLPIIFGDSSKNETQITQWFEKNMNAEVDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNYQIFNTAFSVNKSGQLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESADILTVDLNLNEVEQQRENIPVFKSIKLDLYK
>CP030326.1|AWZ66072.1|2184663_2184798_-|delta-hemolysin-domain-protein
MSCLILRIFILIKEGVISMAQDIISTIGDLVKWIIDTVNKFTKK
>CP030326.1|AWZ66046.1|2184979_2185597_+|accessory-gene-regulator-protein-B
MIKDCTKSYNNSKESGVKLNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFFKILVTYSISIFLSVFLFTLVTHLSYMLIRYNAHGAHAKSSILCYIQSILTFVFVPYFLINIDINFTYLLALSIIGLISVVIYAPAATKKQPIPIKLVKRKKYLSIIMYLLVLILSLIIHPFYAQFMLLGILVESITLLPIFFPKED
>CP030326.1|AWZ65224.1|2185599_2185743_+|cyclic-lactone-autoinducer-peptide-family-protein
MNTLVNMFFDFIIKLAKAIGIVGGVNACSSLFDEPKVPAELTNLYDK

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Crispr_ID: CP030326_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030326_8

2305103-2305183

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of CP030326_8

>merge|CP030326|8|2305103-2305183|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTCAACTTTAGTTGTTAGGGGCTTCT

>CP030326|8|7|2305103-2305183|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTT	ATGCATGCGCTTAGCGCAGGCGCTCCTACTTTT
CAACTTTAGTTGTTAGGGGCTTCT

Protein	Signature genes	Signature genes Name	Protein_function
CP030326.1\|AWZ66429.1\|2295588_2296299_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
CP030326.1\|AWZ65993.1\|2303994_2305086_+\|putative-membrane-protein	unknown	unknown	unknown
CP030326.1\|AWZ65226.1\|2317119_2324565_-\|sasC/Mrp/FmtB-intercellular-aggregation-domain-protein	unknown	unknown	gnl\|CDD\|275089
CP030326.1\|AWZ65811.1\|2296419_2296863_-\|DNA-protection-during-starvation-protein-1	unknown	unknown	gnl\|CDD\|223854
CP030326.1\|AWZ67662.1\|2309057_2310863_-\|glutamine-fructose-6-phosphate-transaminase	unknown	unknown	gnl\|CDD\|234729
CP030326.1\|AWZ66650.1\|2299977_2300208_-\|putative-membrane-protein	unknown	unknown	unknown
CP030326.1\|AWZ67113.1\|2306139_2306310_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226950
CP030326.1\|AWZ66183.1\|2311543_2313082_+\|PTS-system-mannitol-specific-EIICB-component	unknown	unknown	gnl\|CDD\|225123
CP030326.1\|AWZ67538.1\|2302751_2303729_+\|cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter	unknown	unknown	gnl\|CDD\|224151
CP030326.1\|AWZ65786.1\|2300238_2301177_-\|mannose-6-phosphate-isomerase,-class-I	unknown	unknown	gnl\|CDD\|224399
CP030326.1\|AWZ67770.1\|2301612_2302278_-\|NADH(P)-binding-family-protein	unknown	unknown	gnl\|CDD\|187554
CP030326.1\|AWZ65519.1\|2297932_2299306_-\|EVE-domain-protein	unknown	unknown	gnl\|CDD\|376640
CP030326.1\|AWZ67556.1\|2315694_2316801_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
CP030326.1\|AWZ67472.1\|2308043_2308826_-\|ABC-transporter-family-protein	unknown	unknown	gnl\|CDD\|224044
CP030326.1\|AWZ65155.1\|2302429_2302750_+\|HTH-type-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
CP030326.1\|AWZ66689.1\|2313116_2315249_+\|PRD-domain-protein	unknown	unknown	gnl\|CDD\|226234
CP030326.1\|AWZ66319.1\|2315260_2315695_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014
CP030326.1\|AWZ67355.1\|2306302_2306461_+\|hypothetical-protein	unknown	unknown	unknown
CP030326.1\|AWZ67061.1\|2297062_2297476_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225556
CP030326.1\|AWZ66590.1\|2307118_2307976_-\|HAD-hydrolase,-IIB-family-protein	unknown	unknown	gnl\|CDD\|223635

Protein	Function_ID	Function_description	E-value
CP030326.1\|AWZ66429.1\|2295588_2296299_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
CP030326.1\|AWZ67770.1\|2301612_2302278_-\|NADH(P)-binding-family-protein	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.27122e-47
CP030326.1\|AWZ65226.1\|2317119_2324565_-\|sasC/Mrp/FmtB-intercellular-aggregation-domain-protein	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	1.2997e-108
CP030326.1\|AWZ65811.1\|2296419_2296863_-\|DNA-protection-during-starvation-protein-1	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
CP030326.1\|AWZ67113.1\|2306139_2306310_+\|hypothetical-protein	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.00028059
CP030326.1\|AWZ66183.1\|2311543_2313082_+\|PTS-system-mannitol-specific-EIICB-component	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
CP030326.1\|AWZ67538.1\|2302751_2303729_+\|cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.49165e-107
CP030326.1\|AWZ65786.1\|2300238_2301177_-\|mannose-6-phosphate-isomerase,-class-I	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
CP030326.1\|AWZ67662.1\|2309057_2310863_-\|glutamine-fructose-6-phosphate-transaminase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP030326.1\|AWZ65519.1\|2297932_2299306_-\|EVE-domain-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	4.11455e-06
CP030326.1\|AWZ67556.1\|2315694_2316801_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
CP030326.1\|AWZ67472.1\|2308043_2308826_-\|ABC-transporter-family-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.29094e-106
CP030326.1\|AWZ65155.1\|2302429_2302750_+\|HTH-type-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
CP030326.1\|AWZ66689.1\|2313116_2315249_+\|PRD-domain-protein	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.02509e-68
CP030326.1\|AWZ66319.1\|2315260_2315695_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
CP030326.1\|AWZ67061.1\|2297062_2297476_-\|hypothetical-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
CP030326.1\|AWZ66590.1\|2307118_2307976_-\|HAD-hydrolase,-IIB-family-protein	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	2.39536e-58

>CP030326.1|AWZ65993.1|2303994_2305086_+|putative-membrane-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDKKVVTEPKNTKVENGKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>CP030326.1|AWZ67538.1|2302751_2303729_+|cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter
MSHSHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>CP030326.1|AWZ65155.1|2302429_2302750_+|HTH-type-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>CP030326.1|AWZ67770.1|2301612_2302278_-|NADH(P)-binding-family-protein
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>CP030326.1|AWZ65786.1|2300238_2301177_-|mannose-6-phosphate-isomerase,-class-I
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>CP030326.1|AWZ66650.1|2299977_2300208_-|putative-membrane-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>CP030326.1|AWZ65519.1|2297932_2299306_-|EVE-domain-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVKKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>CP030326.1|AWZ67061.1|2297062_2297476_-|hypothetical-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>CP030326.1|AWZ65811.1|2296419_2296863_-|DNA-protection-during-starvation-protein-1
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>CP030326.1|AWZ66429.1|2295588_2296299_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>CP030326.1|AWZ67113.1|2306139_2306310_+|hypothetical-protein
MSPKDTTRFETKPDHQAQFDWKESINFKTKDNQRIPLYIGVLLLYYSRFIIMHNNE
>CP030326.1|AWZ67355.1|2306302_2306461_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>CP030326.1|AWZ66590.1|2307118_2307976_-|HAD-hydrolase,-IIB-family-protein
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTLDVTAYTNEEDGAAKYLAKHFLAD
>CP030326.1|AWZ67472.1|2308043_2308826_-|ABC-transporter-family-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>CP030326.1|AWZ67662.1|2309057_2310863_-|glutamine-fructose-6-phosphate-transaminase
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>CP030326.1|AWZ66183.1|2311543_2313082_+|PTS-system-mannitol-specific-EIICB-component
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>CP030326.1|AWZ66689.1|2313116_2315249_+|PRD-domain-protein
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>CP030326.1|AWZ66319.1|2315260_2315695_+|mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>CP030326.1|AWZ67556.1|2315694_2316801_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>CP030326.1|AWZ65226.1|2317119_2324565_-|sasC/Mrp/FmtB-intercellular-aggregation-domain-protein
MNLFRQQKFSIRKFNVGIFSALIATVTFISTNPTTASAAEQNQPAQNQPAQPADANTQPNANAGAQANPAAQPANQGGQANPAGGAAQPAGQGNQADPNNAAQAQPGNQAAPANQAGQGNNQATPNNNATPANQTQPANAPAAAQPAAPVAANAQTQDPNASNTGEGSINTTLTFDDPAISTDENRQDPTVTVTDKVNGYSLINNGKIGFVNSELRRSDMFDKNNPQNYQAKGNVAALGRVNANDSTDHGNFNGITKTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLDLQFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGASLKADQFKYEVTLPQGVTYVNDSLTTTFPNGNEDSTVLKNMTVNYDQTANKVTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNVANIDTPKNIDFNEKLTYRTASDVVINNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAEYNKLKQQADTILNEDANHVETANRASQADIDGLVTKLQAALIDNQAAIAELDTKAQEKVTAAQQSKKVTQDEVAALVTKINNDKNNAIAEINKQITSQGVTTEKDNGIAVLEQDVITPTVKPQAKQDIIQAVTTRKQQIKKSNASLQDEKDVANDKIGKIETKAIKDIDAATTNAQVEAIKTKAINDINQTTPATTAKAAALEEFDEVVQAQIDQAPLNPDTTNEEVAEAIERINAAKVSGVKAIEATTTAQDLERVKNEEIFKIENITDSTQTKMDAYKEVRQAATARKAQNATVSNATDEEVAEANAAVDAAQTEGLHDIQVVKSQQEVADTKAKVLDKINAIQTQAKVKPAADTEVENAYNTRKQEIQNSNASTTEEKEAAYTELDAKKQEARTNLDAANTNSDVTTAKDNGIAAINQVQAATTKKSDAKAEIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQAVVTANADIDNATANTDVDNAKTTNEATIAAITPDANVKPAAKQAIADKVQAQETAIDANNGSTTEEKEAAKQQVQTEKTAADAAIDAAHSNVEVEAAKNAEIAKIEAIQPATTTKDNAKQAIATKANERKTAIAQTQDITAEEIAAANADVDNAVTQANSNIEAANSQNDVDQAKTTGETSIDQVTPTVNKKATARNEITAILNNKLQEIQATPDATDEEKQAADAEANTENGKANQAISAATTNAQVDEAKANAEAAINAVTPKVVKKQAAKDEIDQLQATQTNVINNDQNATNEEKEAAIQQLATAVTDAKNNITAATDDNGVDTAKDAGKNSIQSTQPATAVKSNAKNEVDQAVTTQNQAIDNTTGATTEEKNAAKDLVLKAKEKAYQDILNAQTTNDVTQIKDQAVADIQGITADTTIKDVAKDELATKANEQKALIAQTADATTEEKEQANQQVDAQLTQGNQNIENAQSIDDVNTAKDNAIQAIDPIQASTDVKTNARAELLTEMQNKITEILNNNETTNEEKGNDIGPVRAAYEEGLNNINAATTTGDVTTAKDTAVQKVQQLHANPVKKPAGKKELDQAAADKKTQIEQTPNASQQEINDAKQEVDTELNQAKTNVDQSSTNEYVDNAVKEGKAKINAVKTFSEYKKDALAKIEDAYNAKVNEADNSNASTSSEIAEAKQKLAELKQTADQNVNQATSKDDIEVQIHNDLDNINDYTIPTGKKESATTDLYAYADQKKNNISADTNATQDEKQQAIKQVDQNVQTALENINNGVDNGDVDDALTQGKAAIDTIQVDATVKPKANQAIEAKAEDTKESIDHSDQLTAEEKTEALAMIKQITDQAKQGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVDADATTEEKEAFTNALEDILSKATEDISDQTTNAEIATVKNSALEQLKAQRINPVVKKNALEAIREVVNKQIEIIKNADADASAKEIARTDLGRYFDRFADKLDKTQTNTEVAELQNVTIPAIEAIVPQNDPDANDTNNGTDNNDATANSNANATPENTGQPNVSETTDNGKADASPTTPNNSDAATGETTVTSATDDAKDKPQANNNSSADASTNSPTMDNDVTSKPEVESTNNGTTDKPVTETDNATPAESTTNNNSTTTATNENAPTGSTATAPTTASTEAASSADSKDNASVNDSKQNAEVNNSAESQSTNGKVAQPKSENKAKAEKDGRDSTNQSMVESTTETLPSADITEPNVPSNTSKDKEESTTNQTDAGQLKSETNVASNEADKSPSKADTEVSNKPSTSASSEAKDKMTSTNVSQKDDTATADTNDTQKSVGPVANNKAKDMQTNDTQKSVGSAANNKATQNDGANASPATVSNGSHSMHQDMLNVTKPEENKANAKSDQQGKVNKPKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKDQQTEE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP030326_4	4.1\|864890\|22\|CP030326\|CRT	864890-864911	22	CP030326.1	181692-181713	0	1.0
CP030326_4	4.1\|864890\|22\|CP030326\|CRT	864890-864911	22	CP030326.1	304768-304789	0	1.0
CP030326_4	4.1\|864890\|22\|CP030326\|CRT	864890-864911	22	CP030326.1	691387-691408	0	1.0
CP030326_4	4.1\|864890\|22\|CP030326\|CRT	864890-864911	22	CP030326.1	817493-817514	0	1.0
CP030326_4	4.1\|864890\|22\|CP030326\|CRT	864890-864911	22	CP030326.1	908154-908175	0	1.0
CP030326_4	4.1\|864890\|22\|CP030326\|CRT	864890-864911	22	CP030326.1	1472550-1472571	0	1.0
CP030326_4	4.1\|864890\|22\|CP030326\|CRT	864890-864911	22	CP030326.1	1561104-1561125	0	1.0
CP030326_4	4.1\|864890\|22\|CP030326\|CRT	864890-864911	22	CP030326.1	1742682-1742703	0	1.0
CP030326_4	4.1\|864890\|22\|CP030326\|CRT	864890-864911	22	CP030326.1	1757216-1757237	0	1.0
CP030326_4	4.1\|864890\|22\|CP030326\|CRT	864890-864911	22	CP030326.1	2074965-2074986	0	1.0
CP030326_4	4.3\|865007\|22\|CP030326\|CRT	865007-865028	22	CP030326.1	181692-181713	0	1.0
CP030326_4	4.3\|865007\|22\|CP030326\|CRT	865007-865028	22	CP030326.1	304768-304789	0	1.0
CP030326_4	4.3\|865007\|22\|CP030326\|CRT	865007-865028	22	CP030326.1	691387-691408	0	1.0
CP030326_4	4.3\|865007\|22\|CP030326\|CRT	865007-865028	22	CP030326.1	817493-817514	0	1.0
CP030326_4	4.3\|865007\|22\|CP030326\|CRT	865007-865028	22	CP030326.1	908154-908175	0	1.0
CP030326_4	4.3\|865007\|22\|CP030326\|CRT	865007-865028	22	CP030326.1	1472550-1472571	0	1.0
CP030326_4	4.3\|865007\|22\|CP030326\|CRT	865007-865028	22	CP030326.1	1561104-1561125	0	1.0
CP030326_4	4.3\|865007\|22\|CP030326\|CRT	865007-865028	22	CP030326.1	1742682-1742703	0	1.0
CP030326_4	4.3\|865007\|22\|CP030326\|CRT	865007-865028	22	CP030326.1	1757216-1757237	0	1.0
CP030326_4	4.3\|865007\|22\|CP030326\|CRT	865007-865028	22	CP030326.1	2074965-2074986	0	1.0
CP030326_7	7.1\|2175871\|34\|CP030326\|CRISPRCasFinder	2175871-2175904	34	CP030326.1	859398-859431	0	1.0
CP030326_7	7.1\|2175871\|34\|CP030326\|CRISPRCasFinder	2175871-2175904	34	CP030326.1	1260903-1260936	0	1.0
CP030326_3	3.1\|859423\|31\|CP030326\|CRISPRCasFinder	859423-859453	31	CP030326.1	1777089-1777119	1	0.968
CP030326_4	4.1\|864890\|22\|CP030326\|CRT	864890-864911	22	CP030326.1	1022475-1022496	1	0.955
CP030326_4	4.1\|864890\|22\|CP030326\|CRT	864890-864911	22	CP030326.1	1776944-1776965	1	0.955
CP030326_4	4.1\|864890\|22\|CP030326\|CRT	864890-864911	22	CP030326.1	1777177-1777198	1	0.955
CP030326_4	4.2\|864948\|23\|CP030326\|CRT	864948-864970	23	CP030326.1	818443-818465	1	0.957
CP030326_4	4.2\|864948\|23\|CP030326\|CRT	864948-864970	23	CP030326.1	818721-818743	1	0.957
CP030326_4	4.2\|864948\|23\|CP030326\|CRT	864948-864970	23	CP030326.1	1472666-1472688	1	0.957
CP030326_4	4.2\|864948\|23\|CP030326\|CRT	864948-864970	23	CP030326.1	2075023-2075045	1	0.957
CP030326_4	4.2\|864948\|23\|CP030326\|CRT	864948-864970	23	CP030326.1	2414635-2414657	1	0.957
CP030326_4	4.3\|865007\|22\|CP030326\|CRT	865007-865028	22	CP030326.1	1022475-1022496	1	0.955
CP030326_4	4.3\|865007\|22\|CP030326\|CRT	865007-865028	22	CP030326.1	1776944-1776965	1	0.955
CP030326_4	4.3\|865007\|22\|CP030326\|CRT	865007-865028	22	CP030326.1	1777177-1777198	1	0.955
CP030326_4	4.4\|865065\|23\|CP030326\|CRT	865065-865087	23	CP030326.1	818443-818465	1	0.957
CP030326_4	4.4\|865065\|23\|CP030326\|CRT	865065-865087	23	CP030326.1	818721-818743	1	0.957
CP030326_4	4.4\|865065\|23\|CP030326\|CRT	865065-865087	23	CP030326.1	1472666-1472688	1	0.957
CP030326_4	4.4\|865065\|23\|CP030326\|CRT	865065-865087	23	CP030326.1	2075023-2075045	1	0.957
CP030326_4	4.4\|865065\|23\|CP030326\|CRT	865065-865087	23	CP030326.1	2414635-2414657	1	0.957
CP030326_5	5.1\|908105\|34\|CP030326\|CRISPRCasFinder	908105-908138	34	CP030326.1	1472646-1472679	1	0.971
CP030326_6	6.1\|1742632\|33\|CP030326\|CRISPRCasFinder	1742632-1742664	33	CP030326.1	1472647-1472679	1	0.97
CP030326_7	7.1\|2175871\|34\|CP030326\|CRISPRCasFinder	2175871-2175904	34	CP030326.1	1869317-1869350	1	0.971
CP030326_10	10.1\|2425489\|31\|CP030326\|CRISPRCasFinder	2425489-2425519	31	CP030326.1	872142-872172	1	0.968
CP030326_10	10.1\|2425489\|31\|CP030326\|CRISPRCasFinder	2425489-2425519	31	CP030326.1	872198-872228	1	0.968
CP030326_4	4.2\|864948\|23\|CP030326\|CRT	864948-864970	23	CP030326.1	1560987-1561009	2	0.913
CP030326_4	4.2\|864948\|23\|CP030326\|CRT	864948-864970	23	CP030326.1	2175928-2175950	2	0.913
CP030326_4	4.4\|865065\|23\|CP030326\|CRT	865065-865087	23	CP030326.1	1560987-1561009	2	0.913
CP030326_4	4.4\|865065\|23\|CP030326\|CRT	865065-865087	23	CP030326.1	2175928-2175950	2	0.913
CP030326_7	7.1\|2175871\|34\|CP030326\|CRISPRCasFinder	2175871-2175904	34	CP030326.1	1477020-1477053	2	0.941
CP030326_7	7.1\|2175871\|34\|CP030326\|CRISPRCasFinder	2175871-2175904	34	CP030326.1	2865285-2865318	2	0.941
CP030326_10	10.1\|2425489\|31\|CP030326\|CRISPRCasFinder	2425489-2425519	31	CP030326.1	83049-83079	2	0.935
CP030326_10	10.1\|2425489\|31\|CP030326\|CRISPRCasFinder	2425489-2425519	31	CP030326.1	424172-424202	2	0.935
CP030326_10	10.1\|2425489\|31\|CP030326\|CRISPRCasFinder	2425489-2425519	31	CP030326.1	691442-691472	2	0.935
CP030326_10	10.1\|2425489\|31\|CP030326\|CRISPRCasFinder	2425489-2425519	31	CP030326.1	908417-908447	2	0.935
CP030326_10	10.1\|2425489\|31\|CP030326\|CRISPRCasFinder	2425489-2425519	31	CP030326.1	1163976-1164006	2	0.935
CP030326_10	10.1\|2425489\|31\|CP030326\|CRISPRCasFinder	2425489-2425519	31	CP030326.1	1266504-1266534	2	0.935
CP030326_10	10.1\|2425489\|31\|CP030326\|CRISPRCasFinder	2425489-2425519	31	CP030326.1	1472605-1472635	2	0.935
CP030326_10	10.1\|2425489\|31\|CP030326\|CRISPRCasFinder	2425489-2425519	31	CP030326.1	1561040-1561070	2	0.935
CP030326_10	10.1\|2425489\|31\|CP030326\|CRISPRCasFinder	2425489-2425519	31	CP030326.1	1561156-1561186	2	0.935
CP030326_10	10.1\|2425489\|31\|CP030326\|CRISPRCasFinder	2425489-2425519	31	CP030326.1	1757270-1757300	2	0.935
CP030326_10	10.1\|2425489\|31\|CP030326\|CRISPRCasFinder	2425489-2425519	31	CP030326.1	2414688-2414718	2	0.935
CP030326_10	10.1\|2425489\|31\|CP030326\|CRISPRCasFinder	2425489-2425519	31	CP030326.1	2591686-2591716	2	0.935

1. spacer 4.1|864890|22|CP030326|CRT matches to position: 181692-181713, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

2. spacer 4.1|864890|22|CP030326|CRT matches to position: 304768-304789, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

3. spacer 4.1|864890|22|CP030326|CRT matches to position: 691387-691408, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

4. spacer 4.1|864890|22|CP030326|CRT matches to position: 817493-817514, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

5. spacer 4.1|864890|22|CP030326|CRT matches to position: 908154-908175, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

6. spacer 4.1|864890|22|CP030326|CRT matches to position: 1472550-1472571, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

7. spacer 4.1|864890|22|CP030326|CRT matches to position: 1561104-1561125, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

8. spacer 4.1|864890|22|CP030326|CRT matches to position: 1742682-1742703, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

9. spacer 4.1|864890|22|CP030326|CRT matches to position: 1757216-1757237, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

10. spacer 4.1|864890|22|CP030326|CRT matches to position: 2074965-2074986, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

11. spacer 4.3|865007|22|CP030326|CRT matches to position: 181692-181713, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

12. spacer 4.3|865007|22|CP030326|CRT matches to position: 304768-304789, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

13. spacer 4.3|865007|22|CP030326|CRT matches to position: 691387-691408, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

14. spacer 4.3|865007|22|CP030326|CRT matches to position: 817493-817514, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

15. spacer 4.3|865007|22|CP030326|CRT matches to position: 908154-908175, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

16. spacer 4.3|865007|22|CP030326|CRT matches to position: 1472550-1472571, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

17. spacer 4.3|865007|22|CP030326|CRT matches to position: 1561104-1561125, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

18. spacer 4.3|865007|22|CP030326|CRT matches to position: 1742682-1742703, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

19. spacer 4.3|865007|22|CP030326|CRT matches to position: 1757216-1757237, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

20. spacer 4.3|865007|22|CP030326|CRT matches to position: 2074965-2074986, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttcgaaa	Protospacer
**********************

21. spacer 7.1|2175871|34|CP030326|CRISPRCasFinder matches to position: 859398-859431, mismatch: 0, identity: 1.0

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctctgtgttgg	Protospacer
**********************************

22. spacer 7.1|2175871|34|CP030326|CRISPRCasFinder matches to position: 1260903-1260936, mismatch: 0, identity: 1.0

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctctgtgttgg	Protospacer
**********************************

23. spacer 3.1|859423|31|CP030326|CRISPRCasFinder matches to position: 1777089-1777119, mismatch: 1, identity: 0.968

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttccattgcc	Protospacer
*********************** *******

24. spacer 4.1|864890|22|CP030326|CRT matches to position: 1022475-1022496, mismatch: 1, identity: 0.955

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttagaaa	Protospacer
***************** ****

25. spacer 4.1|864890|22|CP030326|CRT matches to position: 1776944-1776965, mismatch: 1, identity: 0.955

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttctttacgaaa	Protospacer
**************** *****

26. spacer 4.1|864890|22|CP030326|CRT matches to position: 1777177-1777198, mismatch: 1, identity: 0.955

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttctttacgaaa	Protospacer
**************** *****

27. spacer 4.2|864948|23|CP030326|CRT matches to position: 818443-818465, mismatch: 1, identity: 0.957

tctgtagaaattggaaatccaat	CRISPR spacer
tctgtagaaattgggaatccaat	Protospacer
**************.********

28. spacer 4.2|864948|23|CP030326|CRT matches to position: 818721-818743, mismatch: 1, identity: 0.957

tctgtagaaattggaaatccaat	CRISPR spacer
tctgtagaaattgggaatccaat	Protospacer
**************.********

29. spacer 4.2|864948|23|CP030326|CRT matches to position: 1472666-1472688, mismatch: 1, identity: 0.957

tctgtagaaattggaaatccaat	CRISPR spacer
tctgtagaaattgggaatccaat	Protospacer
**************.********

30. spacer 4.2|864948|23|CP030326|CRT matches to position: 2075023-2075045, mismatch: 1, identity: 0.957

tctgtagaaattggaaatccaat	CRISPR spacer
tctgtagaaattgggaatccaat	Protospacer
**************.********

31. spacer 4.2|864948|23|CP030326|CRT matches to position: 2414635-2414657, mismatch: 1, identity: 0.957

tctgtagaaattggaaatccaat	CRISPR spacer
tctgtagaaattgggaatccaat	Protospacer
**************.********

32. spacer 4.3|865007|22|CP030326|CRT matches to position: 1022475-1022496, mismatch: 1, identity: 0.955

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttcttttagaaa	Protospacer
***************** ****

33. spacer 4.3|865007|22|CP030326|CRT matches to position: 1776944-1776965, mismatch: 1, identity: 0.955

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttctttacgaaa	Protospacer
**************** *****

34. spacer 4.3|865007|22|CP030326|CRT matches to position: 1777177-1777198, mismatch: 1, identity: 0.955

cctgtagaatttcttttcgaaa	CRISPR spacer
cctgtagaatttctttacgaaa	Protospacer
**************** *****

35. spacer 4.4|865065|23|CP030326|CRT matches to position: 818443-818465, mismatch: 1, identity: 0.957

tctgtagaaattggaaatccaat	CRISPR spacer
tctgtagaaattgggaatccaat	Protospacer
**************.********

36. spacer 4.4|865065|23|CP030326|CRT matches to position: 818721-818743, mismatch: 1, identity: 0.957

tctgtagaaattggaaatccaat	CRISPR spacer
tctgtagaaattgggaatccaat	Protospacer
**************.********

37. spacer 4.4|865065|23|CP030326|CRT matches to position: 1472666-1472688, mismatch: 1, identity: 0.957

tctgtagaaattggaaatccaat	CRISPR spacer
tctgtagaaattgggaatccaat	Protospacer
**************.********

38. spacer 4.4|865065|23|CP030326|CRT matches to position: 2075023-2075045, mismatch: 1, identity: 0.957

tctgtagaaattggaaatccaat	CRISPR spacer
tctgtagaaattgggaatccaat	Protospacer
**************.********

39. spacer 4.4|865065|23|CP030326|CRT matches to position: 2414635-2414657, mismatch: 1, identity: 0.957

tctgtagaaattggaaatccaat	CRISPR spacer
tctgtagaaattgggaatccaat	Protospacer
**************.********

40. spacer 5.1|908105|34|CP030326|CRISPRCasFinder matches to position: 1472646-1472679, mismatch: 1, identity: 0.971

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
****.*****************************

41. spacer 6.1|1742632|33|CP030326|CRISPRCasFinder matches to position: 1472647-1472679, mismatch: 1, identity: 0.97

attgggaatccaatttctctgtgttggggccca	CRISPR spacer
attgggaatccaatttctctttgttggggccca	Protospacer
******************** ************

42. spacer 7.1|2175871|34|CP030326|CRISPRCasFinder matches to position: 1869317-1869350, mismatch: 1, identity: 0.971

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctttgtgttgg	Protospacer
*************************.********

43. spacer 10.1|2425489|31|CP030326|CRISPRCasFinder matches to position: 872142-872172, mismatch: 1, identity: 0.968

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgtcagct	Protospacer
***********************.*******

44. spacer 10.1|2425489|31|CP030326|CRISPRCasFinder matches to position: 872198-872228, mismatch: 1, identity: 0.968

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgtcagct	Protospacer
***********************.*******

45. spacer 4.2|864948|23|CP030326|CRT matches to position: 1560987-1561009, mismatch: 2, identity: 0.913

tctgtagaaattggaaatccaat	CRISPR spacer
tctgtagaaattgggaatacaat	Protospacer
**************.*** ****

46. spacer 4.2|864948|23|CP030326|CRT matches to position: 2175928-2175950, mismatch: 2, identity: 0.913

tctgtagaaattggaaatccaat	CRISPR spacer
tctgttgaaattgggaatccaat	Protospacer
***** ********.********

47. spacer 4.4|865065|23|CP030326|CRT matches to position: 1560987-1561009, mismatch: 2, identity: 0.913

tctgtagaaattggaaatccaat	CRISPR spacer
tctgtagaaattgggaatacaat	Protospacer
**************.*** ****

48. spacer 4.4|865065|23|CP030326|CRT matches to position: 2175928-2175950, mismatch: 2, identity: 0.913

tctgtagaaattggaaatccaat	CRISPR spacer
tctgttgaaattgggaatccaat	Protospacer
***** ********.********

49. spacer 7.1|2175871|34|CP030326|CRISPRCasFinder matches to position: 1477020-1477053, mismatch: 2, identity: 0.941

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtggaatttcttatcgaaattctctgtgttgg	Protospacer
****.********* *******************

50. spacer 7.1|2175871|34|CP030326|CRISPRCasFinder matches to position: 2865285-2865318, mismatch: 2, identity: 0.941

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctttttgttgg	Protospacer
*************************.* ******

51. spacer 10.1|2425489|31|CP030326|CRISPRCasFinder matches to position: 83049-83079, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

52. spacer 10.1|2425489|31|CP030326|CRISPRCasFinder matches to position: 424172-424202, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

53. spacer 10.1|2425489|31|CP030326|CRISPRCasFinder matches to position: 691442-691472, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

54. spacer 10.1|2425489|31|CP030326|CRISPRCasFinder matches to position: 908417-908447, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

55. spacer 10.1|2425489|31|CP030326|CRISPRCasFinder matches to position: 1163976-1164006, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

56. spacer 10.1|2425489|31|CP030326|CRISPRCasFinder matches to position: 1266504-1266534, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

57. spacer 10.1|2425489|31|CP030326|CRISPRCasFinder matches to position: 1472605-1472635, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

58. spacer 10.1|2425489|31|CP030326|CRISPRCasFinder matches to position: 1561040-1561070, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

59. spacer 10.1|2425489|31|CP030326|CRISPRCasFinder matches to position: 1561156-1561186, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

60. spacer 10.1|2425489|31|CP030326|CRISPRCasFinder matches to position: 1757270-1757300, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

61. spacer 10.1|2425489|31|CP030326|CRISPRCasFinder matches to position: 2414688-2414718, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

62. spacer 10.1|2425489|31|CP030326|CRISPRCasFinder matches to position: 2591686-2591716, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP030326_4	4.2\|864948\|23\|CP030326\|CRT	864948-864970	23	AP014226	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C9-MedDCM-OCT-S44-C3, * SEQUENCING IN PROGRESS *	28490-28512	3	0.87
CP030326_4	4.2\|864948\|23\|CP030326\|CRT	864948-864970	23	AP014225	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C9-MedDCM-OCT-S41-C89, * SEQUENCING IN PROGRESS *	24653-24675	3	0.87
CP030326_4	4.4\|865065\|23\|CP030326\|CRT	865065-865087	23	AP014226	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C9-MedDCM-OCT-S44-C3, * SEQUENCING IN PROGRESS *	28490-28512	3	0.87
CP030326_4	4.4\|865065\|23\|CP030326\|CRT	865065-865087	23	AP014225	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C9-MedDCM-OCT-S41-C89, * SEQUENCING IN PROGRESS *	24653-24675	3	0.87
CP030326_9	9.1\|2317450\|34\|CP030326\|CRISPRCasFinder	2317450-2317483	34	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	23034-23067	8	0.765
CP030326_9	9.1\|2317450\|34\|CP030326\|CRISPRCasFinder	2317450-2317483	34	CP030544	Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence	7567-7600	8	0.765

1. spacer 4.2|864948|23|CP030326|CRT matches to AP014226 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C9-MedDCM-OCT-S44-C3, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 3, identity: 0.87

tctgtagaaattggaaatccaat	CRISPR spacer
actgtagaaaatggaaatccaac	Protospacer
 ********* ***********.

2. spacer 4.2|864948|23|CP030326|CRT matches to AP014225 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C9-MedDCM-OCT-S41-C89, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 3, identity: 0.87

tctgtagaaattggaaatccaat	CRISPR spacer
actgtagaaaatggaaatccaac	Protospacer
 ********* ***********.

3. spacer 4.4|865065|23|CP030326|CRT matches to AP014226 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C9-MedDCM-OCT-S44-C3, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 3, identity: 0.87

tctgtagaaattggaaatccaat	CRISPR spacer
actgtagaaaatggaaatccaac	Protospacer
 ********* ***********.

4. spacer 4.4|865065|23|CP030326|CRT matches to AP014225 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C9-MedDCM-OCT-S41-C89, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 3, identity: 0.87

tctgtagaaattggaaatccaat	CRISPR spacer
actgtagaaaatggaaatccaac	Protospacer
 ********* ***********.

5. spacer 9.1|2317450|34|CP030326|CRISPRCasFinder matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgcatatctttagctttatagcttttatatgct	Protospacer
******************** *.** .*  **

6. spacer 9.1|2317450|34|CP030326|CRISPRCasFinder matches to CP030544 (Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgaataactttagctttattgttataaacagta	Protospacer
*** *** ****************   *** * .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

360594 : 402858

Staphylococcus_phage(90.62%)

head,tail,holin,portal,integrase,terminase

attL 360484:360501|attR 403590:403607

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
360484:360501	attL	NA	NA	NA	NA
AWZ65423.1\|360594_361800_-\|integrase	phage integrase family protein	Q4ZBP1	Staphylococcus_phage	8.5e-222	100.0
AWZ67018.1\|361910_362090_+	putative excisionase	Q4ZBP0	Staphylococcus_phage	3.7e-25	100.0
AWZ65868.1\|362215_362707_-	hypothetical protein	Q4ZBN8	Staphylococcus_phage	7.5e-84	100.0
AWZ65564.1\|362727_363189_-	hypothetical protein	Q4ZBN7	Staphylococcus_phage	1.2e-83	100.0
AWZ67775.1\|363201_363525_-	helix-turn-helix family protein	A0A0H3U2V8	Staphylococcus_phage	2.0e-53	100.0
AWZ66134.1\|363688_363937_+	helix-turn-helix domain protein	Q4ZBN5	Staphylococcus_phage	2.2e-39	100.0
AWZ65274.1\|363951_364113_+	hypothetical protein	Q4ZBN4	Staphylococcus_phage	1.9e-20	100.0
AWZ67426.1\|364105_364342_-	hypothetical protein	Q4ZBN3	Staphylococcus_phage	2.3e-38	98.7
AWZ65942.1\|364792_364978_+	helix-turn-helix family protein	A0A0H4IP57	Staphylococcus_phage	1.3e-25	100.0
AWZ66398.1\|364979_365732_+	phage antirepressor KilAC domain protein	A0A0E3T9K5	Staphylococcus_phage	4.8e-138	99.2
AWZ67289.1\|365747_365966_+	putative phage protein	Q4ZBN1	Staphylococcus_phage	1.1e-31	100.0
AWZ67351.1\|365995_366259_+	homeo-like domain protein	A0A2I6PEL8	Staphylococcus_phage	2.5e-46	100.0
AWZ66722.1\|366526_366829_+	hypothetical protein	A0A1P8L6F8	Staphylococcus_phage	7.0e-48	100.0
AWZ65872.1\|366833_367094_+	hypothetical protein	A0A1P8L6F5	Staphylococcus_phage	5.2e-44	100.0
AWZ65745.1\|367102_367366_+	putative phage protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
AWZ65288.1\|367374_369318_+	hypothetical protein	A0A1P8L6F1	Staphylococcus_phage	0.0e+00	100.0
AWZ65507.1\|369319_370240_+	recT family protein	A0A1P8L6F6	Staphylococcus_phage	4.3e-165	99.7
AWZ67214.1\|370452_370938_+	beta-lactamase superfamily domain protein	A0A1P8L6F7	Staphylococcus_phage	9.4e-87	100.0
AWZ66987.1\|370938_371409_+	single-stranded DNA-binding family protein	A0A1P8L6D9	Staphylococcus_phage	5.7e-81	100.0
AWZ66305.1\|371438_372332_+	dnaD domain protein	A0A1P8L6F0	Staphylococcus_phage	3.2e-141	100.0
AWZ65473.1\|372338_372557_+	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	1.4e-37	100.0
AWZ65463.1\|372565_372970_+	endodeoxyribonuclease RusA family protein	A0A075M042	Staphylococcus_phage	8.4e-73	100.0
AWZ65348.1\|372982_373351_+	PVL ORF-50-like family protein	A0A0H4J337	Staphylococcus_phage	6.9e-50	96.7
AWZ65854.1\|373354_373597_+	phage family protein	Q4ZBD5	Staphylococcus_virus	1.2e-39	97.5
AWZ66253.1\|373610_373817_+	hypothetical protein	A0A2K9VBT9	Staphylococcus_phage	8.7e-34	98.5
AWZ67573.1\|373819_374221_+	hypothetical protein	Q4ZAC1	Staphylococcus_virus	1.1e-69	100.0
AWZ66154.1\|374217_374565_+	yopX family protein	D2JGL4	Staphylococcus_phage	5.9e-59	100.0
AWZ67537.1\|374561_374870_+	hypothetical protein	R4IFL1	Staphylococcus_phage	4.8e-52	100.0
AWZ66605.1\|374862_375111_+	hypothetical protein	S4V7K0	Staphylococcus_phage	4.1e-38	100.0
AWZ65415.1\|375103_375640_+	dUTPase family protein	A0A0N9BAX6	Staphylococcus_phage	1.6e-95	100.0
AWZ67316.1\|375676_375913_+	hypothetical protein	C8CH06	Staphylococcus_phage	1.1e-35	100.0
AWZ65315.1\|375937_376174_+	hypothetical protein	A0A0N7E0U3	Staphylococcus_phage	1.9e-32	88.5
AWZ66884.1\|376166_376553_+	hypothetical protein	A0A0N9BB01	Staphylococcus_phage	8.0e-65	100.0
AWZ66864.1\|376549_376723_+	transcriptional activator RinB family protein	Q4ZBK0	Staphylococcus_phage	6.4e-22	100.0
AWZ67421.1\|376723_377089_+	hypothetical protein	Q4ZBJ9	Staphylococcus_phage	3.6e-59	100.0
AWZ66184.1\|377089_377236_+	hypothetical protein	Q4ZBJ8	Staphylococcus_phage	7.5e-16	100.0
AWZ65386.1\|377259_377682_+	phage transcriptional regulator, RinA family protein	Q4ZBJ7	Staphylococcus_phage	1.2e-74	100.0
AWZ66683.1\|378009_378504_+\|terminase	terminase small subunit	R4IH30	Staphylococcus_phage	1.1e-74	100.0
AWZ66791.1\|378496_379705_+\|terminase	phage terminase, large subunit, PBSX family	R4IG95	Staphylococcus_phage	3.0e-235	99.8
AWZ67279.1\|379718_381137_+\|portal	phage portal protein, SPP1 family	R4IFL5	Staphylococcus_phage	2.3e-274	99.8
AWZ67570.1\|381411_382056_+\|head	phage head morphogenesis, SPP1 gp7 family domain protein	R4II65	Staphylococcus_phage	2.0e-116	100.0
AWZ66575.1\|382153_382750_+	phage minor structural GP20 family protein	R4IG73	Staphylococcus_phage	5.6e-73	100.0
AWZ67601.1\|382770_383595_+\|head	putative major head protein	R4IH32	Staphylococcus_phage	5.6e-148	100.0
AWZ66965.1\|383611_383938_+	rho termination factor, N-terminal domain protein	A0A0E3TAL3	Staphylococcus_phage	4.3e-51	100.0
AWZ65903.1\|383937_384252_+\|head,tail	phage gp6-like head-tail connector family protein	R4IFL8	Staphylococcus_phage	4.0e-54	100.0
AWZ65216.1\|384244_384580_+\|head,tail	putative head-tail adaptor	A0A2H4PQL0	Staphylococcus_phage	3.0e-60	100.0
AWZ65939.1\|384566_384980_+	hypothetical protein	R4IG77	Staphylococcus_phage	2.0e-77	100.0
AWZ66550.1\|384992_385430_+	hypothetical protein	A0A0E3T9M9	Staphylococcus_phage	7.9e-77	99.3
AWZ66746.1\|385416_385977_+\|tail	putative tail protein	A0A0H4ITY2	Staphylococcus_phage	5.9e-101	100.0
AWZ66137.1\|386038_386533_+	phage family protein	R4IFM1	Staphylococcus_phage	4.3e-87	100.0
AWZ66662.1\|386553_386895_+	hypothetical protein	A0A2H4PQL5	Staphylococcus_phage	3.5e-56	100.0
AWZ66510.1\|386897_389867_+	TMP repeat family protein	Q4ZAG7	Staphylococcus_virus	1.9e-262	99.1
AWZ66490.1\|389881_390817_+\|tail	phage tail family protein	R4IH41	Staphylococcus_phage	8.2e-180	100.0
AWZ67443.1\|390827_392714_+\|tail	prophage endopeptidase tail family protein	R4IGA4	Staphylococcus_phage	0.0e+00	99.7
AWZ67411.1\|392726_394625_+	putative minor structural protein	A0A0H3U448	Staphylococcus_phage	0.0e+00	98.4
AWZ65758.1\|394624_396448_+	hypothetical protein	B1H3M3	Staphylococcus_phage	0.0e+00	99.8
AWZ66461.1\|396447_396825_+	hypothetical protein	Q8LTH7	Staphylococcus_phage	7.3e-55	100.0
AWZ67264.1\|396828_397002_+	hypothetical protein	Q8LTH6	Staphylococcus_phage	1.7e-27	100.0
AWZ66844.1\|397042_397342_+	hypothetical protein	Q4ZBP8	Staphylococcus_phage	1.3e-46	100.0
AWZ67022.1\|397478_399353_+	CHAP domain protein	A0A2I6PCX0	Staphylococcus_phage	0.0e+00	100.0
AWZ66361.1\|399365_400538_+	hypothetical protein	A0EWN2	Staphylococcus_virus	2.4e-197	99.7
AWZ67626.1\|400543_400939_+	hypothetical protein	A9CRD5	Staphylococcus_phage	4.7e-68	99.2
AWZ67283.1\|400994_401432_+\|holin	holin, phage phi LC3 family	A7YGY0	Staphylococcus_virus	5.9e-72	97.9
AWZ67602.1\|401412_402858_+	CHAP domain protein	Q4ZB16	Staphylococcus_virus	3.8e-293	99.0
403590:403607	attR	NA	NA	NA	NA

DBSCAN-SWA_2

796571 : 804392

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ67444.1\|796571_797627_-	histidine protein kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
AWZ66020.1\|797626_798295_-	response regulator	NA	NA	NA	NA
AWZ65390.1\|798287_798761_-	doxX family protein	NA	NA	NA	NA
AWZ66056.1\|799103_799544_-	electron transfer DM13 family protein	NA	NA	NA	NA
AWZ65298.1\|799823_800408_-	putative membrane protein	NA	NA	NA	NA
AWZ67470.1\|800506_801220_-	7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
AWZ65906.1\|801223_801643_-	queuosine biosynthesis protein QueD	S4U060	uncultured_phage	6.3e-07	28.7
AWZ66938.1\|801644_802313_-	queuosine biosynthesis protein QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
AWZ66945.1\|802663_803257_+	glutamine amidotransferase of anthranilate synthase/aminodeoxychorismate synthase family protein	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
AWZ66019.1\|803240_804392_+	chorismate binding enzyme family protein	S4VNU7	Pandoravirus	6.0e-23	35.7

DBSCAN-SWA_3

816363 : 831004

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ65414.1\|816363_817422_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
AWZ66797.1\|817760_818303_+	putative 5'(3')-deoxyribonucleotidase	NA	NA	NA	NA
AWZ67368.1\|819181_820099_-	putative lipid kinase	A0A1V0SBJ0	Catovirus	2.1e-07	22.0
AWZ66076.1\|820368_821874_-	H+ symporter family protein	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
AWZ67145.1\|822214_822715_-	7-cyano-7-deazaguanine reductase	E7DN65	Pneumococcus_phage	5.9e-52	71.5
AWZ66696.1\|822734_823601_-	eamA-like transporter family protein	NA	NA	NA	NA
AWZ67605.1\|824401_824800_+	nrdI protein	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
AWZ67482.1\|824771_826868_+	ribonucleoside-diphosphate reductase, alpha subunit	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
AWZ65194.1\|826985_827957_+	ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
AWZ66847.1\|828331_829303_+	fecCD transport family protein	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
AWZ66606.1\|829289_830246_+	fecCD transport family protein	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
AWZ67451.1\|830242_831004_+	ABC transporter family protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6

DBSCAN-SWA_4

916492 : 973414

Staphylococcus_phage(76.12%)

head,tail,holin,portal,capsid,integrase,terminase,transposase

attL 914580:914596|attR 949234:949250

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
914580:914596	attL	NA	NA	NA	NA
AWZ65428.1\|916492_917734_+	putative cysteine desulfurase	Q2XUY6	environmental_halophage	8.2e-111	44.8
AWZ66235.1\|917723_918188_+	SUF system FeS assembly protein, NifU family	NA	NA	NA	NA
AWZ67346.1\|918338_919736_+	feS assembly protein SufB	NA	NA	NA	NA
AWZ65711.1\|919803_920853_-\|integrase	phage integrase family protein	A1KWY3	Staphylococcus_virus	4.5e-203	99.7
AWZ66735.1\|920965_921145_+	putative excisionase	A0EWN7	Staphylococcus_virus	8.3e-25	100.0
AWZ65665.1\|921124_922057_-	putative phage protein	A0EWN8	Staphylococcus_virus	3.9e-174	100.0
AWZ66295.1\|922088_922814_-	short C-terminal domain protein	A0A0F6N4L7	Staphylococcus_phage	9.9e-125	100.0
AWZ67493.1\|922841_923516_-	hypothetical protein	A0A0F6N3H6	Staphylococcus_phage	4.9e-126	100.0
AWZ66279.1\|923532_923820_-	helix-turn-helix family protein	A0A0F6N3H8	Staphylococcus_phage	2.3e-48	100.0
AWZ66214.1\|924127_924322_+	helix-turn-helix family protein	A0A0F6N3M9	Staphylococcus_phage	1.1e-25	100.0
AWZ65295.1\|924321_925089_+	phage antirepressor KilAC domain protein	A0A0F6N3N8	Staphylococcus_phage	1.1e-142	100.0
AWZ67159.1\|925089_925314_+	hypothetical protein	A0A0F6N4M2	Staphylococcus_phage	3.2e-34	100.0
AWZ65539.1\|925353_925803_+	hypothetical protein	A1KWZ2	Staphylococcus_virus	3.0e-79	100.0
AWZ66617.1\|925816_926038_+	hypothetical protein	A0A0F6N3I2	Staphylococcus_phage	1.5e-31	100.0
AWZ67209.1\|926285_926588_+	hypothetical protein	A0A0F6N3N3	Staphylococcus_phage	1.4e-48	100.0
AWZ65172.1\|926592_926853_+	hypothetical protein	Q4ZDA1	Staphylococcus_virus	1.2e-43	100.0
AWZ65217.1\|926862_927084_+	hypothetical protein	A7TWM6	Staphylococcus_phage	3.2e-34	100.0
AWZ65440.1\|927076_927700_+	hypothetical protein	A0A2H4PQQ6	Staphylococcus_phage	1.4e-114	100.0
AWZ67684.1\|927699_928128_+	single-stranded DNA-binding protein ssb	B2ZYV4	Staphylococcus_phage	3.9e-60	100.0
AWZ67349.1\|928141_928816_+	hypothetical protein	R4IH15	Staphylococcus_phage	1.4e-125	96.9
AWZ67109.1\|928954_929236_-	pTS system, fructose subfamily, IIA component domain protein	A0A1W6JPU7	Staphylococcus_phage	2.6e-49	100.0
AWZ65324.1\|929301_930072_+	conserved phage family protein	G4KNP0	Staphylococcus_phage	6.4e-122	100.0
AWZ66143.1\|930081_930861_+	istB-like ATP binding family protein	G4KNP1	Staphylococcus_phage	3.8e-146	100.0
AWZ66967.1\|930899_931013_+	hypothetical protein	A0A2H4PQI7	Staphylococcus_phage	1.6e-13	100.0
AWZ65352.1\|931025_931247_+	hypothetical protein	A0A0H3U2V4	Staphylococcus_phage	2.2e-35	100.0
AWZ65370.1\|931256_931661_+	hypothetical protein	A1KX76	Staphylococcus_virus	9.6e-69	100.0
AWZ66899.1\|931665_931851_+	hypothetical protein	A0A0F6N3K7	Staphylococcus_phage	1.1e-27	100.0
AWZ66975.1\|931851_932157_+	hypothetical protein	A0A0F6N4H9	Staphylococcus_phage	1.7e-49	100.0
AWZ65815.1\|932284_932641_+	PVL ORF-50-like family protein	A0A0F6N3E3	Staphylococcus_phage	6.5e-61	100.0
AWZ65189.1\|932644_932887_+	phage family protein	A0A0F6N3E1	Staphylococcus_phage	1.9e-40	98.8
AWZ65736.1\|932901_933267_+	acetyltransferase family protein	A0A0F6N3K4	Staphylococcus_phage	3.5e-54	100.0
AWZ67670.1\|933259_933514_+	hypothetical protein	A1KX15	Staphylococcus_virus	2.5e-38	97.6
AWZ66723.1\|933500_933671_+	hypothetical protein	A7TWH6	Staphylococcus_phage	1.5e-20	91.1
AWZ65698.1\|933663_934197_+	dUTP diphosphatase family protein	A1KX16	Staphylococcus_virus	2.4e-96	99.4
AWZ65382.1\|934233_934440_+	hypothetical protein	A0A0H3U2R7	Staphylococcus_phage	1.0e-18	72.1
AWZ66231.1\|934436_934631_+	hypothetical protein	A0A2I6PEC2	Staphylococcus_phage	6.0e-29	100.0
AWZ65185.1\|934627_934831_+	hypothetical protein	A0A0N9BAX5	Staphylococcus_phage	5.2e-31	100.0
AWZ66964.1\|934823_935060_+	hypothetical protein	Q4ZDP0	Staphylococcus_virus	2.8e-36	100.0
AWZ66106.1\|935052_935226_+	transcriptional activator RinB family protein	Q4ZBK0	Staphylococcus_phage	6.4e-22	100.0
AWZ66770.1\|935396_935819_+	phage transcriptional regulator, RinA family protein	A0A0F6N3E5	Staphylococcus_phage	1.2e-74	100.0
AWZ66161.1\|936006_936501_+\|terminase	terminase small subunit	A0A0F6N3K6	Staphylococcus_phage	7.8e-89	100.0
AWZ65576.1\|936503_937799_+\|terminase	phage terminase, large subunit, PBSX family	A0A0F6N3L3	Staphylococcus_phage	3.0e-257	100.0
AWZ66801.1\|937809_939348_+\|portal	phage portal protein, SPP1 family	A0A0F6N4I8	Staphylococcus_phage	2.4e-293	100.0
AWZ66166.1\|939354_940350_+\|head	phage head morphogenesis, SPP1 gp7 family domain protein	A0A0F6N3F1	Staphylococcus_phage	2.0e-184	100.0
AWZ67439.1\|940422_940593_+	hypothetical protein	A0A0F6N3E9	Staphylococcus_phage	1.5e-23	100.0
AWZ66237.1\|940701_941322_+	hypothetical protein	S4V984	Staphylococcus_phage	1.7e-69	98.5
AWZ65111.1\|941335_942310_+\|capsid	phage major capsid protein, HK97 family	E0Y3L0	Staphylococcus_virus	2.2e-183	100.0
AWZ66836.1\|942331_942619_+	hypothetical protein	S4V6D9	Staphylococcus_phage	1.4e-45	98.9
AWZ65351.1\|942627_942960_+\|head,tail	phage gp6-like head-tail connector family protein	A0A0F6N3F4	Staphylococcus_phage	5.5e-54	100.0
AWZ65310.1\|943258_943606_+	hypothetical protein	A0A0F6N3F5	Staphylococcus_phage	4.1e-60	100.0
AWZ66635.1\|943617_944001_+	hypothetical protein	E0Y3L5	Staphylococcus_virus	3.8e-67	98.4
AWZ66860.1\|944019_944601_+\|tail	phage major tail protein, TP901-1 family	A0A0F6N3L8	Staphylococcus_phage	4.9e-106	100.0
AWZ65435.1\|944662_945028_+	phage family protein	A0A0F6N4J9	Staphylococcus_phage	3.6e-59	100.0
AWZ66160.1\|945057_945402_+	hypothetical protein	A0A0F6N3F7	Staphylococcus_phage	2.5e-57	100.0
AWZ66918.1\|945418_948886_+	putative membrane protein	A0A0F6N3F9	Staphylococcus_phage	4.2e-245	100.0
AWZ66177.1\|948898_949846_+\|tail	phage tail family protein	A0A0F6N3L4	Staphylococcus_phage	2.8e-183	100.0
949234:949250	attR	NA	NA	NA	NA
AWZ67352.1\|949854_951756_+\|tail	prophage endopeptidase tail family protein	I1W634	Staphylococcus_phage	0.0e+00	99.7
AWZ65106.1\|951770_953681_+	putative minor structural protein	Q4ZDU1	Staphylococcus_virus	0.0e+00	98.7
AWZ65160.1\|953680_955504_+	hypothetical protein	A1KX42	Staphylococcus_virus	3.9e-295	99.2
AWZ66345.1\|955503_955881_+	hypothetical protein	A0A0F6N3G4	Staphylococcus_phage	1.5e-60	100.0
AWZ67118.1\|955884_956058_+	hypothetical protein	A0A0F6N3L7	Staphylococcus_phage	6.6e-27	100.0
AWZ66167.1\|956097_956397_+	hypothetical protein	A0A0H4ITZ0	Staphylococcus_phage	7.6e-47	100.0
AWZ67754.1\|956533_958432_+	mannosyl-glycoendo-beta-N-acetylglucosaminidase family protein	A0EX80	Staphylococcus_virus	0.0e+00	99.7
AWZ65165.1\|958444_959683_+	hypothetical protein	A0A0F6N3G7	Staphylococcus_phage	1.6e-210	100.0
AWZ65787.1\|959688_960084_+	hypothetical protein	A1KXB6	Staphylococcus_virus	1.6e-68	100.0
AWZ67591.1\|960139_960415_+\|holin	holin, SPP1 family	A0A0F6N3M0	Staphylococcus_phage	8.6e-45	100.0
AWZ66594.1\|960401_961814_+	CHAP domain protein	A0A0F6N3N1	Staphylococcus_phage	5.8e-286	100.0
AWZ65720.1\|961873_962431_-	putative penicillin binding protein	A0A0F6N4L1	Staphylococcus_phage	7.4e-96	100.0
AWZ67293.1\|963125_963326_+	hypothetical protein	W5R9N2	Staphylococcus_phage	3.7e-29	100.0
AWZ65078.1\|964155_964470_-	putative membrane protein	NA	NA	NA	NA
AWZ66315.1\|964834_965875_+	hypothetical protein	NA	NA	NA	NA
AWZ67635.1\|965888_966956_+	nitronate monooxygenase family protein	NA	NA	NA	NA
AWZ65542.1\|967340_968189_+	hypothetical protein	NA	NA	NA	NA
AWZ66639.1\|968201_969029_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
AWZ66572.1\|969055_970375_+	5'-nucleotidase, C-terminal domain protein	NA	NA	NA	NA
AWZ65905.1\|970458_971376_+	lipoyl synthase	NA	NA	NA	NA
AWZ66747.1\|971505_971889_+	hypothetical protein	NA	NA	NA	NA
AWZ67038.1\|972094_973414_+\|transposase	transposase family protein	NA	NA	NA	NA

DBSCAN-SWA_5

1072595 : 1134145

Staphylococcus_phage(89.23%)

head,tail,holin,portal,protease,capsid,integrase,terminase,bacteriocin

attL 1075441:1075467|attR 1120944:1120970

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ67298.1\|1072595_1074158_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	1.7e-36	28.2
AWZ67485.1\|1074465_1075263_+	integral membrane, YkoY family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
1075441:1075467	attL	NA	NA	NA	NA
AWZ65508.1\|1075551_1076757_-\|integrase	phage integrase family protein	B7T0F2	Staphylococcus_virus	1.2e-218	98.5
AWZ66506.1\|1076882_1077497_+	hypothetical protein	A7TW88	Staphylococcus_phage	7.9e-107	100.0
AWZ65323.1\|1077493_1077619_-	hypothetical protein	A0A2I6PF02	Staphylococcus_phage	5.1e-13	100.0
AWZ65712.1\|1077869_1078454_-	hypothetical protein	A0A2I6PD77	Staphylococcus_phage	1.4e-68	100.0
AWZ66182.1\|1078471_1078933_-	hypothetical protein	A0A2K9VBR7	Staphylococcus_phage	1.2e-83	100.0
AWZ66306.1\|1078945_1079260_-	helix-turn-helix family protein	A0A0N9BAW4	Staphylococcus_phage	9.8e-53	100.0
AWZ66832.1\|1079411_1079648_+	cro/C1-type HTH DNA-binding domain protein	A0A2I6PD81	Staphylococcus_phage	1.5e-37	100.0
AWZ67513.1\|1079661_1080438_+	phage regulatory, Rha family protein	A0A2I6PD87	Staphylococcus_phage	1.1e-140	100.0
AWZ66038.1\|1080466_1080610_+	hypothetical protein	W5R8I6	Staphylococcus_phage	2.5e-16	100.0
AWZ65608.1\|1080599_1080809_-	hypothetical protein	W5R9J5	Staphylococcus_phage	1.2e-30	100.0
AWZ67301.1\|1080864_1081110_+	hypothetical protein	A0A2I6PF15	Staphylococcus_phage	5.1e-41	100.0
AWZ66554.1\|1081078_1081444_-	putative phage protein	A0A2I6PF07	Staphylococcus_phage	2.4e-63	100.0
AWZ67625.1\|1081498_1081714_+	hypothetical protein	A0A2I6PF01	Staphylococcus_phage	1.9e-31	100.0
AWZ67309.1\|1081738_1082002_+	homeo-like domain protein	A7TWG0	Staphylococcus_phage	5.7e-46	100.0
AWZ66673.1\|1082254_1082578_+	hypothetical protein	A0A2I6PF12	Staphylococcus_phage	8.5e-52	99.1
AWZ67367.1\|1082592_1082955_+	hypothetical protein	A0A2I6PF03	Staphylococcus_phage	4.9e-56	100.0
AWZ67166.1\|1082951_1084118_+	hypothetical protein	A0A2D1G5B8	Staphylococcus_phage	8.3e-222	100.0
AWZ65471.1\|1084143_1084701_+	hypothetical protein	A0A2I6PF05	Staphylococcus_phage	1.8e-97	100.0
AWZ65526.1\|1084769_1086722_+	DNA polymerase A family protein	A0A2I6PE86	Staphylococcus_phage	0.0e+00	99.8
AWZ65188.1\|1086734_1086920_+	hypothetical protein	A0A2I6PEM8	Staphylococcus_phage	2.1e-26	98.4
AWZ66376.1\|1086919_1087321_+	PVL ORF-50-like family protein	A0A2I6PEL5	Staphylococcus_phage	1.2e-68	100.0
AWZ67337.1\|1087350_1087575_+	hypothetical protein	Q6R831	Staphylococcus_virus	1.8e-37	100.0
AWZ66517.1\|1087580_1087823_+	phage family protein	A0A2K9VBX5	Staphylococcus_phage	1.1e-40	100.0
AWZ66079.1\|1087836_1088043_+	hypothetical protein	A0A2K9VBT9	Staphylococcus_phage	1.1e-33	97.1
AWZ66086.1\|1088045_1088783_+	yopX family protein	Q4ZBK8	Staphylococcus_phage	5.5e-62	89.6
AWZ67705.1\|1088779_1089169_+	acetyltransferase family protein	A0A0F6N3K4	Staphylococcus_phage	9.9e-47	92.5
AWZ66841.1\|1089161_1089410_+	hypothetical protein	A0A0E3T8I2	Staphylococcus_phage	4.5e-37	97.6
AWZ66535.1\|1089402_1089939_+	dUTPase family protein	A0A1P8L6E0	Staphylococcus_phage	2.1e-95	100.0
AWZ65651.1\|1089975_1090182_+	hypothetical protein	A0A0H3U2R7	Staphylococcus_phage	1.3e-29	100.0
AWZ65943.1\|1090178_1090565_+	hypothetical protein	A0A0H3U465	Staphylococcus_phage	5.2e-64	100.0
AWZ67438.1\|1090561_1090714_+	transcriptional activator RinB family protein	A0A2I6PEM5	Staphylococcus_phage	2.0e-19	100.0
AWZ66826.1\|1090781_1090982_+	hypothetical protein	A0A2I6PEP5	Staphylococcus_phage	4.9e-26	100.0
AWZ67141.1\|1091269_1093717_+	virulence-associated E family protein	B5WZN5	Staphylococcus_phage	0.0e+00	99.8
AWZ65767.1\|1094057_1094348_+	VRR-NUC domain protein	A0A2I6PEN7	Staphylococcus_phage	6.5e-51	100.0
AWZ65784.1\|1094424_1095696_+	DEAD/DEAH box helicase family protein	A0A1X9IH01	Staphylococcus_phage	4.2e-243	100.0
AWZ66499.1\|1095708_1096146_+	phage transcriptional regulator, RinA family protein	A0A2I6PDC2	Staphylococcus_phage	4.6e-77	100.0
AWZ66820.1\|1096302_1096617_+	HNH endonuclease family protein	A0A2I6PDC4	Staphylococcus_phage	2.5e-56	100.0
AWZ66465.1\|1096745_1097051_+\|terminase	phage terminase, small subunit	A0A2I6PE27	Staphylococcus_phage	2.9e-49	100.0
AWZ66852.1\|1097040_1098732_+	phage Terminase family protein	A0A2I6PE44	Staphylococcus_phage	0.0e+00	100.0
AWZ67075.1\|1098736_1099975_+\|portal	phage portal protein, HK97 family	A0A2I6PEA6	Staphylococcus_phage	6.9e-235	100.0
AWZ67441.1\|1099958_1100732_+\|protease	clp protease family protein	A0A2I6PE26	Staphylococcus_phage	4.9e-138	100.0
AWZ67647.1\|1100743_1101907_+\|capsid	phage major capsid protein, HK97 family	A0A2I6PE62	Staphylococcus_phage	3.6e-217	100.0
AWZ67555.1\|1101975_1102254_+\|head,tail	phage gp6-like head-tail connector family protein	A0A2I6PE36	Staphylococcus_phage	2.1e-46	100.0
AWZ65622.1\|1102346_1102598_+	hypothetical protein	A0A2I6PDD6	Staphylococcus_phage	1.2e-40	100.0
AWZ65279.1\|1102594_1102996_+	hypothetical protein	A0A2I6PDD3	Staphylococcus_phage	6.2e-68	100.0
AWZ65666.1\|1102996_1103392_+	hypothetical protein	A0A2I6PDD8	Staphylococcus_phage	2.6e-66	100.0
AWZ65621.1\|1103426_1104068_+\|tail	phage major tail, phi13 family protein	A0A2I6PE59	Staphylococcus_phage	1.0e-120	100.0
AWZ65688.1\|1104159_1104615_+	bacterial Ig-like domain family protein	A0A2I6PER6	Staphylococcus_phage	5.7e-78	100.0
AWZ67494.1\|1104672_1105023_+	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
AWZ66693.1\|1105064_1105223_+	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
AWZ65141.1\|1105236_1111437_+\|tail	phage tail tape measure protein, TP901 family, core region	M9QQM6	Staphylococcus_phage	0.0e+00	99.4
AWZ65306.1\|1111436_1112261_+\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
AWZ66308.1\|1112269_1113853_+\|tail	prophage endopeptidase tail family protein	Q8SDP1	Staphylococcus_virus	7.1e-309	100.0
AWZ67629.1\|1113852_1114143_+	hypothetical protein	R4WEC3	Staphylococcus_phage	2.1e-49	100.0
AWZ65990.1\|1114158_1116069_+	putative minor structural protein	A0A2K9VBU3	Staphylococcus_phage	0.0e+00	100.0
AWZ67079.1\|1116068_1117535_+	hypothetical protein	A0A2I6PDE3	Staphylococcus_phage	1.3e-272	99.4
AWZ67732.1\|1117534_1117924_+	hypothetical protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
AWZ66148.1\|1117916_1118081_+	hypothetical protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
AWZ66061.1\|1118126_1118426_+	hypothetical protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
AWZ65740.1\|1118561_1118999_+\|holin	holin, phage phi LC3 family	A0A2H4PQP0	Staphylococcus_phage	4.1e-73	100.0
AWZ65400.1\|1118979_1120425_+	CHAP domain protein	A0A0H3U310	Staphylococcus_phage	2.2e-296	99.8
AWZ65753.1\|1120999_1123309_+	trypsin-like peptidase domain protein	W5SAB9	Pithovirus	2.8e-11	27.4
1120944:1120970	attR	NA	NA	NA	NA
AWZ66738.1\|1123325_1124684_+	cation transport family protein	NA	NA	NA	NA
AWZ66926.1\|1124822_1126334_+	5'-nucleotidase, C-terminal domain protein	NA	NA	NA	NA
AWZ66162.1\|1126820_1127390_-	comK family protein	NA	NA	NA	NA
AWZ65793.1\|1127599_1127818_+	IDEAL domain protein	NA	NA	NA	NA
AWZ66919.1\|1127898_1128885_-	lipoyltransferase and lipoate-ligase family protein	NA	NA	NA	NA
AWZ67292.1\|1129083_1129260_+	hypothetical protein	NA	NA	NA	NA
AWZ65967.1\|1129274_1129877_+\|protease	CAAX protease self-immunity family protein	NA	NA	NA	NA
AWZ66908.1\|1131219_1133184_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
AWZ67252.1\|1133186_1133507_+	hypothetical protein	NA	NA	NA	NA
AWZ66873.1\|1133503_1134145_+\|bacteriocin	putative bacteriocin ABC transporter family protein	G9BWD6	Planktothrix_phage	1.7e-19	33.0

DBSCAN-SWA_6

1165549 : 1173959

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ66676.1\|1165549_1165969_+	phosphoribosylaminoimidazole carboxylase, catalytic subunit	A0A2P0VNU7	Tetraselmis_virus	1.6e-18	45.8
AWZ67788.1\|1165955_1167080_+	N5-carboxyaminoimidazole ribonucleotide synthase	NA	NA	NA	NA
AWZ67388.1\|1167083_1167788_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
AWZ66221.1\|1167787_1168051_+	phosphoribosylformylglycinamidine synthase, purS protein	NA	NA	NA	NA
AWZ67785.1\|1168052_1168724_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
AWZ67250.1\|1168716_1170906_+	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	3.5e-141	39.8
AWZ67274.1\|1170884_1172369_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.9e-45	31.7
AWZ65879.1\|1172361_1173390_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
AWZ67063.1\|1173392_1173959_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_7

1792276 : 1801319

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ65634.1\|1792276_1792795_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
AWZ67458.1\|1792816_1795090_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	8.1e-64	29.3
AWZ66509.1\|1795292_1797572_-	protein-export membrane protein SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
AWZ66455.1\|1797846_1798107_-	preprotein translocase, YajC subunit	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
AWZ67384.1\|1798125_1799265_-\|tRNA	queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
AWZ66472.1\|1799287_1800313_-\|tRNA	tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
AWZ66541.1\|1800314_1801319_-	holliday junction DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_8

1922034 : 1992656

Staphylococcus_phage(91.67%)

tRNA,protease,integrase,transposase

attL 1939597:1939613|attR 1988058:1988074

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ65363.1\|1922034_1922679_-\|tRNA	tRNA (guanine-N(7)-)-methyltransferase	NA	NA	NA	NA
AWZ66648.1\|1922693_1923485_-	phosphotransferase enzyme family protein	NA	NA	NA	NA
AWZ66111.1\|1924034_1924883_-	D-amino-acid transaminase	NA	NA	NA	NA
AWZ67652.1\|1924886_1926296_-	dipeptidase family protein	NA	NA	NA	NA
AWZ66436.1\|1926739_1927162_-	hypothetical protein	NA	NA	NA	NA
AWZ67188.1\|1927178_1927874_-	pseudouridine synthase family protein	NA	NA	NA	NA
AWZ65359.1\|1927870_1929532_-	matE family protein	NA	NA	NA	NA
AWZ65825.1\|1929938_1931207_+	flavo, HI0933 family protein	A0A2H4PQX1	Staphylococcus_phage	9.1e-57	99.1
AWZ65653.1\|1931323_1937884_-	sasC/Mrp/FmtB intercellular aggregation domain protein	A0A2H4PQU6	Staphylococcus_phage	6.1e-306	98.3
AWZ67325.1\|1938209_1938521_-	rhodanese-like domain protein	A0A2H4PQR9	Staphylococcus_phage	4.8e-52	99.0
AWZ67179.1\|1938542_1940957_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.5
1939597:1939613	attL	NA	NA	NA	NA
AWZ65263.1\|1941247_1942429_-	sugar (and other) transporter family protein	A0A2H4PQR6	Staphylococcus_phage	7.3e-218	99.7
AWZ65486.1\|1942538_1943492_+	radical SAM superfamily protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
AWZ65577.1\|1943488_1944052_+	rRNA methylase family protein	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
AWZ65695.1\|1944174_1944576_-	HTH-type transcriptional regulator rot	NA	NA	NA	NA
AWZ67660.1\|1945147_1945975_-	alpha/beta hydrolase family protein	NA	NA	NA	NA
AWZ65553.1\|1946207_1947209_+	proline dehydrogenase family protein	A0A2H4PQT6	Staphylococcus_phage	2.6e-184	99.4
AWZ67329.1\|1947330_1947795_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.5e-70	100.0
AWZ67057.1\|1947807_1948989_-	riboflavin biosynthesis protein RibBA	A0A2H4PQS2	Staphylococcus_phage	5.6e-226	99.5
AWZ66607.1\|1948999_1949632_-	riboflavin synthase, alpha subunit	A0A2H4PQS5	Staphylococcus_phage	5.5e-111	98.6
AWZ65730.1\|1949638_1950682_-	riboflavin biosynthesis protein RibD	A0A2H4PQS8	Staphylococcus_phage	5.3e-196	98.8
AWZ65819.1\|1951162_1952665_-	FAD-NAD(P)-binding family protein	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
AWZ66341.1\|1953501_1954794_+	arsenite/antimonite efflux pump membrane family protein	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
AWZ65552.1\|1954880_1955735_-	mannosyl-glycoendo-beta-N-acetylglucosaminidase family protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
AWZ65093.1\|1956010_1956235_-	hypothetical protein	NA	NA	NA	NA
AWZ66540.1\|1956433_1956904_+	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	8.8e-82	98.1
AWZ67406.1\|1957316_1957460_+	hypothetical protein	NA	NA	NA	NA
AWZ65267.1\|1957446_1957890_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
AWZ66907.1\|1958185_1958821_+\|protease	CAAX protease self-immunity family protein	NA	NA	NA	NA
AWZ65080.1\|1959260_1959974_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
AWZ67663.1\|1960233_1960536_+	putative membrane protein	NA	NA	NA	NA
AWZ66227.1\|1960791_1961157_+	crcB-like family protein	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
AWZ65912.1\|1961153_1961507_+	crcB-like family protein	A0A2H4PQQ7	Staphylococcus_phage	3.8e-21	94.0
AWZ67509.1\|1962154_1962319_+\|transposase	putative transposase	A0A146ICT8	Staphylococcus_phage	2.9e-24	98.1
AWZ65301.1\|1962757_1963441_+\|transposase	transposase DDE domain protein	A0ZS58	Staphylococcus_virus	1.2e-124	96.5
AWZ67559.1\|1963503_1964337_-	aldo/keto reductase family protein	A0A2H4PQR8	Staphylococcus_phage	7.8e-158	99.3
AWZ65855.1\|1964548_1965457_-	nuclease-related domain protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
AWZ65350.1\|1965578_1966775_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.3e-218	99.5
AWZ65171.1\|1967146_1968739_+	phosphoenolpyruvate carboxykinase	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
AWZ65983.1\|1969116_1969887_-	prolyl oligopeptidase family protein	A0A2H4PQM6	Staphylococcus_phage	1.5e-142	98.8
AWZ67256.1\|1969867_1970347_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	3.0e-85	99.4
AWZ65915.1\|1970406_1970664_+	putative membrane protein insertion efficiency factor	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
AWZ65087.1\|1970660_1971662_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	5.3e-185	97.3
AWZ65304.1\|1971666_1972458_-	O-succinylbenzoate-CoA ligase	A0A2H4PQM9	Staphylococcus_phage	3.7e-149	97.7
AWZ67163.1\|1973303_1973786_-	hypothetical protein	A0A2H4PQN7	Staphylococcus_phage	3.8e-80	99.3
AWZ67290.1\|1974098_1974713_+	excalibur calcium-binding domain protein	A0A2H4PQM8	Staphylococcus_phage	1.1e-42	93.1
AWZ67442.1\|1974793_1975789_+	hypothetical protein	A0A2H4PQN2	Staphylococcus_phage	2.6e-67	97.9
AWZ65476.1\|1975863_1976490_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	3.1e-74	79.8
AWZ65085.1\|1976530_1976872_+	hypothetical protein	A0A2H4PQN6	Staphylococcus_phage	1.1e-54	94.7
AWZ65818.1\|1976972_1977545_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	2.3e-23	93.1
AWZ65113.1\|1977742_1978312_-\|integrase	integrase core domain protein	A0A2I7SC85	Paenibacillus_phage	1.3e-55	56.8
AWZ65686.1\|1979342_1979720_-\|transposase	putative transposase	NA	NA	NA	NA
AWZ65362.1\|1979766_1979898_+	hypothetical protein	NA	NA	NA	NA
AWZ65456.1\|1980294_1981524_-	type I restriction modification DNA specificity domain protein	A0A2H4PQP5	Staphylococcus_phage	4.0e-134	64.7
AWZ66992.1\|1981516_1983073_-	type I restriction-modification system, M subunit	A0A2H4PQP4	Staphylococcus_phage	1.6e-289	100.0
AWZ66031.1\|1983433_1984153_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.0e-129	98.3
AWZ67370.1\|1984273_1984993_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.3e-129	98.7
AWZ66657.1\|1985050_1985773_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	3.5e-130	98.3
AWZ67146.1\|1985897_1986605_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	7.9e-127	97.0
AWZ65495.1\|1987568_1988150_+	hypothetical protein	A0A2H4PQH6	Staphylococcus_phage	9.6e-54	64.8
1988058:1988074	attR	NA	NA	NA	NA
AWZ65683.1\|1988299_1988419_+	hypothetical protein	NA	NA	NA	NA
AWZ67031.1\|1988622_1988895_-	putative membrane protein	A0A2H4PQH0	Staphylococcus_phage	3.1e-31	83.5
AWZ65195.1\|1989096_1989570_+	hypothetical protein	NA	NA	NA	NA
AWZ67618.1\|1989574_1990366_+	hypothetical protein	NA	NA	NA	NA
AWZ65151.1\|1990352_1990478_-	hypothetical protein	NA	NA	NA	NA
AWZ65418.1\|1990735_1991719_-	leucotoxin LukDv	A0A2H4PQH7	Staphylococcus_phage	1.8e-185	99.4
AWZ65959.1\|1991720_1992656_-	leucotoxin LukEv	A0A2H4PQI5	Staphylococcus_phage	5.1e-174	99.7

DBSCAN-SWA_9

1998857 : 2003104

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ67246.1\|1998857_1999613_-	enterotoxin H	A0A075M4C7	Staphylococcus_phage	6.0e-40	41.4
AWZ66332.1\|1999651_2000047_-	enterotoxin type C-1	A0A097PAT7	Streptococcus_pyogenes_phage	1.5e-26	50.4
AWZ65589.1\|2000021_2000369_-	enterotoxin type B	A0A097PAT7	Streptococcus_pyogenes_phage	3.0e-10	37.9
AWZ66397.1\|2000576_2001305_-	toxin beta-grasp domain protein	A0A1X9H080	Staphylococcus_phage	1.1e-27	39.2
AWZ66620.1\|2001339_2002059_-	toxin beta-grasp domain protein	A0A1X9H080	Staphylococcus_phage	2.3e-25	35.8
AWZ66853.1\|2002339_2003104_-	enterotoxin type D	A0A1X9H080	Staphylococcus_phage	2.3e-31	37.1

DBSCAN-SWA_10

2128027 : 2173967

Staphylococcus_phage(95.65%)

head,tail,holin,integrase,portal,capsid,protease

attL 2147455:2147472|attR 2171951:2171968

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ65313.1\|2128027_2128225_+	phospholipase C domain protein	A0A1P8L6A7	Staphylococcus_phage	3.4e-27	100.0
AWZ66988.1\|2128596_2128776_+	putative membrane protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
AWZ67135.1\|2128855_2129011_-	hypothetical protein	A0A1P8L6A1	Staphylococcus_phage	1.4e-20	100.0
AWZ66356.1\|2129155_2129347_+	putative membrane protein	M9NS66	Staphylococcus_phage	1.7e-23	100.0
AWZ66798.1\|2129399_2129750_-	complement inhibitor	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
AWZ66994.1\|2130434_2130884_+	chemotaxis inhibitory protein	A0A1P8L6A8	Staphylococcus_phage	1.1e-78	100.0
AWZ65982.1\|2130978_2131275_-	bacterial SH3 domain protein	A0A1P8L6B4	Staphylococcus_phage	1.3e-51	100.0
AWZ67518.1\|2131963_2132455_-	staphylokinase	A0A1X9H028	Staphylococcus_phage	9.5e-87	100.0
AWZ66062.1\|2132645_2133401_-	CHAP domain protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
AWZ66838.1\|2133412_2133667_-\|holin	holin, phage phi LC3 family	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
AWZ67035.1\|2133878_2134013_-	putative membrane protein	D2JLG3	Staphylococcus_phage	9.3e-13	100.0
AWZ65280.1\|2134204_2134501_-	hypothetical protein	D2JLG2	Staphylococcus_phage	2.9e-46	100.0
AWZ67220.1\|2134558_2134846_-	hypothetical protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
AWZ65840.1\|2134892_2135045_-	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
AWZ66984.1\|2135034_2138820_-	phage minor structural, N-terminal region domain protein	Q6R866	Staphylococcus_virus	0.0e+00	98.3
AWZ66719.1\|2138835_2140320_-\|tail	phage tail family protein	A0A2I6PDJ0	Staphylococcus_phage	4.5e-297	99.8
AWZ65103.1\|2140316_2144849_-\|tail	phage tail tape measure protein, TP901 family, core region	A0EX03	Staphylococcus_phage	0.0e+00	98.9
AWZ65068.1\|2144905_2145043_-	hypothetical protein	A0A2I6PDX7	Staphylococcus_phage	3.4e-18	100.0
AWZ67133.1\|2145093_2145444_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
AWZ66185.1\|2145493_2145634_-	bacterial Ig-like domain family protein	A0A2I6PDK6	Staphylococcus_phage	2.5e-16	100.0
AWZ67681.1\|2145759_2146404_-\|tail	phage major tail, phi13 family protein	G4KNQ7	Staphylococcus_phage	1.9e-119	99.1
AWZ67584.1\|2146404_2146812_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
AWZ67772.1\|2146808_2147213_-	hypothetical protein	A0A1W6JPJ1	Staphylococcus_phage	2.5e-69	100.0
AWZ66627.1\|2147209_2147572_-\|head,tail	phage head-tail joining family protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
2147455:2147472	attL	NA	NA	NA	NA
AWZ65342.1\|2147555_2147840_-\|head,tail	phage gp6-like head-tail connector family protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
AWZ65900.1\|2147852_2148113_-	hypothetical protein	A0A0H3U504	Staphylococcus_phage	1.4e-41	98.8
AWZ67239.1\|2148132_2149278_-\|capsid	phage major capsid protein, HK97 family	A0A1W6JPL4	Staphylococcus_phage	7.3e-215	99.7
AWZ66373.1\|2149300_2150038_-\|protease	clp protease family protein	A0A1W6JPK0	Staphylococcus_phage	1.8e-129	100.0
AWZ66667.1\|2150021_2151185_-\|portal	phage portal protein, HK97 family	A0A1W6JPQ9	Staphylococcus_phage	1.8e-216	100.0
AWZ66928.1\|2151200_2152862_-	phage Terminase family protein	A0A075M4D3	Staphylococcus_phage	0.0e+00	100.0
AWZ66497.1\|2152858_2153203_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
AWZ67740.1\|2153333_2153633_-	HNH endonuclease family protein	A0A2I6PDH9	Staphylococcus_phage	3.5e-52	100.0
AWZ67554.1\|2153864_2154281_-	phage transcriptional regulator, RinA family protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
AWZ65152.1\|2154308_2154509_-	hypothetical protein	D2JLD9	Staphylococcus_phage	5.3e-28	98.5
AWZ67148.1\|2154508_2154658_-	transcriptional activator RinB family protein	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
AWZ66761.1\|2154654_2154861_-	hypothetical protein	A0A2I6PEA2	Staphylococcus_phage	1.1e-17	94.1
AWZ67235.1\|2154857_2155103_-	putative membrane protein	A0A2I6PDW7	Staphylococcus_phage	2.5e-35	98.8
AWZ66366.1\|2155139_2155676_-	dUTPase family protein	Q9MBR0	Staphylococcus_prophage	1.6e-95	100.0
AWZ65976.1\|2155672_2155918_-	hypothetical protein	Q8SDV5	Staphylococcus_phage	1.7e-36	95.1
AWZ65480.1\|2155932_2156175_-	phage family protein	A0A2H4PQJ3	Staphylococcus_phage	1.2e-39	98.8
AWZ67787.1\|2156177_2156435_-	hypothetical protein	A0A1X9H067	Staphylococcus_phage	6.3e-42	98.8
AWZ65717.1\|2156434_2156806_-	PVL ORF-50-like family protein	A0A2I6PDG3	Staphylococcus_phage	3.7e-51	91.1
AWZ67284.1\|2156818_2157223_-	endodeoxyribonuclease RusA family protein	A0A075M042	Staphylococcus_phage	8.4e-73	100.0
AWZ65431.1\|2157231_2157450_-	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	1.4e-37	100.0
AWZ65319.1\|2157456_2158350_-	dnaD domain protein	A0A1P8L6F0	Staphylococcus_phage	3.2e-141	100.0
AWZ65676.1\|2158379_2158850_-	single-stranded DNA-binding family protein	A0A1P8L6D9	Staphylococcus_phage	5.7e-81	100.0
AWZ67005.1\|2158850_2159336_-	beta-lactamase superfamily domain protein	A0A1P8L6F7	Staphylococcus_phage	9.4e-87	100.0
AWZ66449.1\|2159548_2160469_-	recT family protein	A0A1P8L6F6	Staphylococcus_phage	5.1e-166	100.0
AWZ66944.1\|2160470_2162414_-	hypothetical protein	A0A1P8L6F1	Staphylococcus_phage	0.0e+00	100.0
AWZ66122.1\|2162422_2162686_-	putative phage protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
AWZ65894.1\|2162694_2162955_-	hypothetical protein	A0A1P8L6F5	Staphylococcus_phage	5.2e-44	100.0
AWZ67058.1\|2162959_2163262_-	hypothetical protein	A0A1P8L6F8	Staphylococcus_phage	7.0e-48	100.0
AWZ66104.1\|2163356_2163518_-	hypothetical protein	A0A1P8L6G0	Staphylococcus_phage	1.9e-20	100.0
AWZ67668.1\|2163514_2163838_-	hypothetical protein	A0A075LYF5	Staphylococcus_phage	3.0e-57	100.0
AWZ67019.1\|2163892_2164273_+	hypothetical protein	Q9T1Z5	Staphylococcus_phage	1.2e-68	100.0
AWZ66412.1\|2164259_2164457_-	putative phi PVL orf 35-like protein	O80075	Staphylococcus_phage	3.5e-24	87.7
AWZ66752.1\|2164472_2165222_-	phage antirepressor KilAC domain protein	B7T097	Staphylococcus_virus	3.4e-136	99.6
AWZ67579.1\|2165480_2165621_-	hypothetical protein	A0A2I6PDT8	Staphylococcus_phage	1.9e-16	100.0
AWZ65360.1\|2165635_2166079_-	hypothetical protein	W5R971	Staphylococcus_phage	1.5e-75	100.0
AWZ66034.1\|2166497_2167214_+	helix-turn-helix family protein	A0A1X9H038	Staphylococcus_phage	5.4e-131	100.0
AWZ65700.1\|2167225_2168080_+	HIRAN domain protein	A0A1X9H037	Staphylococcus_phage	7.3e-151	100.0
AWZ66265.1\|2168153_2168300_+	hypothetical protein	A0A1X9H032	Staphylococcus_phage	3.3e-19	100.0
AWZ66149.1\|2168296_2168482_+	hypothetical protein	U5U7D6	Staphylococcus_phage	2.3e-25	100.0
AWZ66511.1\|2168552_2168735_+	hypothetical protein	A0A0H3U4Z4	Staphylococcus_phage	6.9e-27	96.7
AWZ67315.1\|2168813_2169527_+	pemK-like family protein	A0A1X9H026	Staphylococcus_phage	5.0e-129	100.0
AWZ65207.1\|2169717_2170755_+\|integrase	integrase	Q38086	Staphylococcus_phage	2.2e-178	99.7
AWZ66527.1\|2170811_2171636_+	sphingomyelin phosphodiesterase	A0A1P8L6H7	Staphylococcus_phage	8.9e-162	99.6
AWZ66316.1\|2171873_2172890_-	gamma-hemolysin component B	A0A1X9IGW5	Staphylococcus_phage	6.7e-26	30.2
2171951:2171968	attR	NA	NA	NA	NA
AWZ65241.1\|2172911_2173967_-	hypothetical protein	A0A1X9IGW5	Staphylococcus_phage	2.8e-35	34.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP030325

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CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP030326

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection