CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP022582	Staphylococcus aureus strain FORC_062 chromosome, complete genome	10 crisprs	cas3,DEDDh,DinG,csa3,RT,WYL	10	1	11	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP022582_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022582_1

183198-183282

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022582_1

>merge|CP022582|1|183198-183282|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGTGTGGGCCCCAACAAAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGGTG

>CP022582|1|1|183198-183282|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGTG	TGGGCCCCAACAAAGAGAAATTGGATTCCCAAT
TTCTACAGACAATGCAAGTTGGGGTG

Protein	Signature genes	Signature genes Name	Protein_function
CP022582.1\|AXI04925.1\|177602_178748_+\|UDP-N-acetylglucosamine-2-epimerase	unknown	unknown	gnl\|CDD\|223458
CP022582.1\|AXI04931.1\|183725_184238_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379428
CP022582.1\|AXI04935.1\|187075_188107_+\|butyryl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
CP022582.1\|AXI04923.1\|175322_176210_+\|UDP-glucose-4-epimerase	unknown	unknown	gnl\|CDD\|187543
CP022582.1\|AXI04922.1\|174765_175323_+\|Galactosyl-transferase	unknown	unknown	gnl\|CDD\|225059
CP022582.1\|AXI04938.1\|190267_191518_+\|putative-membrane-protein	unknown	unknown	gnl\|CDD\|340887
CP022582.1\|AXI04930.1\|183343_183547_-\|hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI04928.1\|179955_181443_+\|Aldehyde-dehydrogenase-B	unknown	unknown	gnl\|CDD\|143435
CP022582.1\|AXI04929.1\|182089_183049_+\|Cobalt-zinc-cadmium-resistance-protein	unknown	unknown	gnl\|CDD\|224151
CP022582.1\|AXI04932.1\|184579_185320_+\|Nitrate-ABC-transporter	unknown	unknown	gnl\|CDD\|224041
CP022582.1\|AXI04933.1\|185333_186305_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|270271
CP022582.1\|AXI04920.1\|172343_173549_+\|Capsular-polysaccharide-synthesis-enzyme-Cap5K	unknown	unknown	unknown
CP022582.1\|AXI04926.1\|178812_179139_-\|Heme-degrading-monooxygenase-IsdG	unknown	unknown	gnl\|CDD\|183968
CP022582.1\|AXI04927.1\|179145_179529_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377291
CP022582.1\|AXI04937.1\|188757_189882_+\|NAD-dependent-formate-dehydrogenase	unknown	unknown	gnl\|CDD\|181041
CP022582.1\|AXI04939.1\|191946_199140_+\|gramicidin-S-synthetase-2-related-protein	unknown	unknown	gnl\|CDD\|237108
CP022582.1\|AXI04936.1\|188422_188683_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227896
CP022582.1\|AXI04921.1\|173549_174755_+\|Glycosyl-transferases-group-1	unknown	unknown	gnl\|CDD\|340825
CP022582.1\|AXI04924.1\|176263_177526_+\|UDP-glucose-6-dehydrogenase	unknown	unknown	gnl\|CDD\|223749
CP022582.1\|AXI04934.1\|186301_187063_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673

Protein	Function_ID	Function_description	E-value
CP022582.1\|AXI04925.1\|177602_178748_+\|UDP-N-acetylglucosamine-2-epimerase	gnl\|CDD\|223458	COG0381, WecB, UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane].	0
CP022582.1\|AXI04931.1\|183725_184238_+\|hypothetical-protein	gnl\|CDD\|379428	pfam14026, DUF4242, Protein of unknown function (DUF4242). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 90 and 170 amino acids in length. There is a single completely conserved residue C that may be functionally important.	2.56603e-26
CP022582.1\|AXI04923.1\|175322_176210_+\|UDP-glucose-4-epimerase	gnl\|CDD\|187543	cd05232, UDP_G4E_4_SDR_e, UDP-glucose 4 epimerase, subgroup 4, extended (e) SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup is comprised of bacterial proteins, and includes the Staphylococcus aureus capsular polysaccharide Cap5N, which may have a role in the synthesis of UDP-N-acetyl-d-fucosamine. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.93098e-117
CP022582.1\|AXI04922.1\|174765_175323_+\|Galactosyl-transferase	gnl\|CDD\|225059	COG2148, WcaJ, Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane].	3.08096e-87
CP022582.1\|AXI04938.1\|190267_191518_+\|putative-membrane-protein	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.61322e-72
CP022582.1\|AXI04936.1\|188422_188683_+\|hypothetical-protein	gnl\|CDD\|227896	COG5609, COG5609, Uncharacterized conserved protein [Function unknown].	6.31332e-32
CP022582.1\|AXI04928.1\|179955_181443_+\|Aldehyde-dehydrogenase-B	gnl\|CDD\|143435	cd07117, ALDH_StaphAldA1, Uncharacterized Staphylococcus aureus AldA1 (SACOL0154) aldehyde dehydrogenase-like. Uncharacterized aldehyde dehydrogenase from Staphylococcus aureus (AldA1, locus SACOL0154) and other similar sequences are present in this CD.	0
CP022582.1\|AXI04929.1\|182089_183049_+\|Cobalt-zinc-cadmium-resistance-protein	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	4.11026e-108
CP022582.1\|AXI04932.1\|184579_185320_+\|Nitrate-ABC-transporter	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	2.18703e-112
CP022582.1\|AXI04933.1\|185333_186305_+\|hypothetical-protein	gnl\|CDD\|270271	cd13553, PBP2_NrtA_CpmA_like, Substrate binding domain of ABC-type nitrate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes nitrate (NrtA) and bicarbonate (CmpA) receptors. These domains are found in eubacterial perisplamic-binding proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. These binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.75927e-52
CP022582.1\|AXI04935.1\|187075_188107_+\|butyryl-CoA-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	2.67474e-20
CP022582.1\|AXI04926.1\|178812_179139_-\|Heme-degrading-monooxygenase-IsdG	gnl\|CDD\|183968	PRK13313, PRK13313, staphylobilin-forming heme oxygenase IsdI.	1.40112e-64
CP022582.1\|AXI04927.1\|179145_179529_-\|hypothetical-protein	gnl\|CDD\|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	5.80598e-41
CP022582.1\|AXI04937.1\|188757_189882_+\|NAD-dependent-formate-dehydrogenase	gnl\|CDD\|181041	PRK07574, PRK07574, NAD-dependent formate dehydrogenase.	0
CP022582.1\|AXI04939.1\|191946_199140_+\|gramicidin-S-synthetase-2-related-protein	gnl\|CDD\|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
CP022582.1\|AXI04921.1\|173549_174755_+\|Glycosyl-transferases-group-1	gnl\|CDD\|340825	cd03794, GT4_WbuB-like, Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.	3.56278e-74
CP022582.1\|AXI04924.1\|176263_177526_+\|UDP-glucose-6-dehydrogenase	gnl\|CDD\|223749	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane].	0
CP022582.1\|AXI04934.1\|186301_187063_+\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	1.22607e-73

>CP022582.1|AXI04929.1|182089_183049_+|Cobalt-zinc-cadmium-resistance-protein
MNGKKANTINRYKYFHHVNHQKIQQSSKKTLWASLIITLLFTVIEFVGGLVSNSLALLSDSFHMLSDVLALGLSMLAIYFASKKPTARYTFGYLRFEILVAFLNGLALIVISIWILYEAIVRIIYPQPIESGIMFMIASIGLLVNIILTIILVRSLKQEDNINIQSALWHFMGDLLNSIGVIVAVVLIYFTGWRIIDPIISIVISLIILRGGYKITRNAWLILMESVPQHLDTDQIMADIKNIDGILDVHEFHLWSITTEHYSLSAHVVLDKKYEGDDYQAIDQVSSLLKEKYGIAHSTLQIENLQLNPLDEPYFDKLT
>CP022582.1|AXI04928.1|179955_181443_+|Aldehyde-dehydrogenase-B
MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQEAFESWSLTSKSERAQMLRDIGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPKGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVGDPQDEATQMGSQTGKDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEIFGPVLTVIKVKDDQEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQVKNIYIDTSNALKGLY
>CP022582.1|AXI04927.1|179145_179529_-|hypothetical-protein
MRLILIVIGLIFTALGIAGAVLPLLPTTPFLLVAVFCFARSSDRFYNWLINQKIYKEYVENFYLHRGYTLQQKIKILISLYIVIGFSIYMVDVLAVRVGLIIMVIIQTAVLFTFVKTLPKSNHKIEE
>CP022582.1|AXI04926.1|178812_179139_-|Heme-degrading-monooxygenase-IsdG
MFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLNTEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDIGYHYQK
>CP022582.1|AXI04925.1|177602_178748_+|UDP-N-acetylglucosamine-2-epimerase
MKKIMVIFGTRPEAIKMAPLVKEIDHNGNFEANIVITAQHRDMLDSVLSIFDIQADHDLNIMQDQQTLADLTANALAKLDSIINEEQPDMILVHGDTTTTFVGSLAAFYHQIPVGHVEAGLRTHQKYSPFPEELNRVMVSNIAELNFAPTVIAAKNLLFENKDKERIFITGNTVIDALSTTVQNDFVSTIINKHKGKKVILLTAHRRENIGEPMHQIFKAVRDLADEYKDVVFIYPMHRNPKVRAIAEKYLSGRNRIELIEPLDAIEFHNFTNQSYLVLTDSGGIQEEAPTFGKPVLVLRNHTERPEGVEAGTSRVIGTDYDNIVRNVKQLIEDDEAYQRMSQANNPYGDGQASRRICEAIEYYFGLRSDKPDEFVPLRHK
>CP022582.1|AXI04924.1|176263_177526_+|UDP-glucose-6-dehydrogenase
MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQSGQISIEEPGLQEVYEEVLSSGKLKVSTTPEASDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLEKGNTIIVESTIAPKTMDDFVKPVIENLGFTIGEDICLVHCPERVLPGKILEELVHNNRIIGGVTKACIEAGKYVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALANELTKICNNLNINVLDVIEMANKHPRVNIHQPGPGVGGHCLAVDPYFIIAKDPENAKLIQTGREINNSMPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLNQEPDIEVCAYDPHVELDFVEHDMSHAVKDASLVLILSDHSEFKNLSDSHFDKMKHKVIFDTKNVVKSSFEDVSYYNYGNIFNFIDK
>CP022582.1|AXI04923.1|175322_176210_+|UDP-glucose-4-epimerase
MRKNILITGVHGYIGNALKDKLIEQGHQVDQINVRNQLWKSTSFKDYDVLIHTAALVHNNSPQARLSDYMQVNMLLTKQLAQKAKAEDVKQFIFMSTMAVYGKEGQVGKSDQIDTQTPMNPTTNYGISKKFAEQALQELISDSFKVAIVRPPMIYGAHCPGNFQRLMQLSKRLPIIPNINNQRSALYIKHLTAFIDQLISLEVTGVYHPQDSFYFDTSSVMYEIRRQSHRKTVLINMPSVLNKYFNKLSVFRKLFGNLTYSNTLYENNNALEVIPGKMSLVIADIMDETTTKDKA
>CP022582.1|AXI04922.1|174765_175323_+|Galactosyl-transferase
MKRLFDVVSSIYGLVVLSPILLITALLIKMESPGPAIFKQKRPTINNELFNIYKFRSMKIDTPNVATDLMDSTSYITKTGKVIRKTSIDELPQLLNVLKGEMSIVGPRPALYNQYELIEKRTKANVHTIRPGVTGLAQVMGRDDITDDQKVAYDHYYLTHQSMMLDMYIIYKTIKNIVTSEGVHH
>CP022582.1|AXI04921.1|173549_174755_+|Glycosyl-transferases-group-1
MSEKKILILCQYFYPEYVSSATLPTQLAEDLIANHINVDVMCGWPYEYSNHKQVSKTEMHRGIRIRRLKYSRFNNKSKVGRIINFFSLFSKFVINIPKMLKYDQILVYSNPPILPLIPDVLHRLLKKKYSFVVYDIAPDNAIKTGATRPGSMIDKLMRYINRHVYKNAENVIVLGTEMKNYLLNHQISKNADNIHVIPNWYDMRQLQDNRIYNDTFKAYREQYDKILLYSGNMGQLQDMETLISFLKLNKDQPQTLTILCGHGKKFADVKTAIEDHRIENVKMFEFLTGTDYADVLKIADVCIASLIKEGVGLGVPSKNYGYLAAKKPLVLIMDKQSDIVQHVEQYDAGIQIDNGDAHAIYNFINTHSSKELHEMGERAHQLFKDKYTREINTMKYYNLLK
>CP022582.1|AXI04920.1|172343_173549_+|Capsular-polysaccharide-synthesis-enzyme-Cap5K
MVKKVFIMDSVKTIIGTLLIALGLQFLAYPIINQRVGNEAFGSILTIYTIITITSVVLGNTLNNIRLINMNLYKSNHYYWKFVSILLISILIESIALIIVFLYFFNLNTIDIIFLILLNILMCLRIYLNVFFRMTLKYNQILYIALIQFLGLLIGLFLYYLIQNWIVCFITSELFATIYTLVKLRGLTIGEYQSEDNNVVKDYVMLLSTNSLNNLNLYLDRLILLPIIGGTAVTISFLSTFIGKMLATFLYPINNVVLSYISVNESDNIKKQYLKTNLFAIAALCLVMIICYPITLIIVSLLYNIDSSLYSKFIILGNIGVLFNAVSIMIQTLNTKHASITLQANYMTLHTITFIFITILMTIAFGLNGFFWTTLFSNIIKYVILNIIGLKSKFINKKDVD
>CP022582.1|AXI04930.1|183343_183547_-|hypothetical-protein
MDKESVVASLARNKKIAVETMAGQRYIIERILHTNDEKHIHILKPKDVVLDVDSIKEIDENHLNDAT
>CP022582.1|AXI04931.1|183725_184238_+|hypothetical-protein
MTLFLLEANNLDFASTKEELEAKAASLSTKTIPTLIEVQATENLTHGYFIVEANDEAEAKQFLTEADISIQLVKEVRLVGKDLDEVKNGDAHVDYLVTWNIPEGITMDQYLARKKKNSVHYEEVPEVEFKRTYVCEDMSKCICLYNAPDEEAVRRARKAVDTPIDGIEKL
>CP022582.1|AXI04932.1|184579_185320_+|Nitrate-ABC-transporter
MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNVIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHNLLPWKTINDNIRIGFQQKISDEEINAQLKLVDLEDRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLQDQLVQLKHKTQSTIILVTHDIDEAIYLSDRIVLLGEGCNIISQYEITASHPRSRNDSHLLKIRNEIMETFALNHHQVEPEYYL
>CP022582.1|AXI04933.1|185333_186305_+|hypothetical-protein
MKRLSIIVIIGIFIITGCDWQRTSKEPSKNAQNQQVIKIGYLPITHSANLMMTKKLLSQYNHPKYKLELVKFNNWPDLMDALNSGRIDGASTLIELAMKSKQKGSNIKAVALGHHEGNVIMGQKGMHLNEFNNGDDYHFGIPHRYSTHYLLLEELRKQLKIKPGHFSYHEMSPAEMPAALSEHRITGYSVAEPFGALGEKLGKGKTLKHGDDVIPDAYCCVLVLRGELLDQHKDVAQAFVQDYKKSGFKMNDRKQSVDIMTHHFKQSRDVLTQSAAWTSYGDLTIKPSGYQEITTLVKQHHLFNPPAYDDFVEPSLYKEASRS
>CP022582.1|AXI04934.1|186301_187063_+|ABC-transporter-permease
MTRPTNNKFILPIITFIIFLGIWEMVIIIGHYQPVLLPGPALVGKSIWTFIVTGEIFQHLAISLWRFVAGFVVALLVAIPLGFLLGRNRWLYNAIEPLFQLIRPISPIAWAPFVVLWFGIGSLPAIAIIFIAAFFPIVFNTIKGVRDIEPQYLKIAANLNLTGWSLYRNILFPGAFKQIMAGIHMAVGTSWIFLVSGEMIGAQSGLGFLIVDARNMLNLEDVLAAIFFIGLFGFIIDRFISYIEQFILRRFGE
>CP022582.1|AXI04935.1|187075_188107_+|butyryl-CoA-dehydrogenase
MTLETLIKEQLDPHLVEVDEGTYYPRTFIQQLFVDGYFGEAALRKNAEVIEAVSQSCLTTGFCLWCQLAFSTYLENATQPHLNNDLQQQLLSGEILGATGLSNPMKSFNDLEKLNLEHTYVDGQLVVSGRMPAVSNIQEDHYFGAISKHESSDEFVMFILRANQDGITLVEKTNFLGVNGSATYQITLNQVVVPQSQIITHDAKQFAATIRPQFIAYQIPIGLGSIKSSLELIDAFSNAQNGINQYLEYDVEAFKKRYRQLREEYYAILDDGNLTSHLSELISLKKDIGYLLLDVNQASVVNGGSRAYTPYSPQVRKLKEGFFFAALTPTLRHLGKLEAELKG
>CP022582.1|AXI04936.1|188422_188683_+|hypothetical-protein
MSFKDNWAIAHMTGVLSKVESFYLNDKRNESMLHYTRTEKIKQMYKEIDVNEMESLVGAKFVKLFTDIDLNDDEVISIFVFDKSIE
>CP022582.1|AXI04937.1|188757_189882_+|NAD-dependent-formate-dehydrogenase
MSNGAVFFVIFLKQATCNTYFKEVKIYHLGEMDMKIVALFPEAVEGQENQLLNTKKAIGLKTFLEERGHEFIILADNGEDLDKHLPDMDVIISAPFYPAYMTRERIEKAPNLKLAITAGVGSDHVDLAAASEHNIGVVEVTGSNTVSVAEHAVMDLLILLRNYEEGHRQSVEGEWNLSQVGNHAHELQHKTIGIFGFGRIGQLVAERLAPFNVTLQHYDPINQQDHKLSKFVSFDELVSSSDAITIHAPLTPETDNLFDKDVLSRMKKHSYLVNTARGKIVNRDALVEALASEHLQGYAGDVWYPQPAPADHPWRTMPRNAMTVHYSGMTLEAQKRIEDGVKDILERFFNHEPFQDKDIIVASGRIASKSYTAK
>CP022582.1|AXI04938.1|190267_191518_+|putative-membrane-protein
MKRLSTTLKVRLISNFLQLIITTAFIPFIALYLTDMLSQSIVGIYLVGLVVLKFPLSIISGYLIEIFPKKLLVLIYQATMVIMLVFMGVFGSHQLWQIIGFCVAYAIFTIVWGLQFPVMDTLIMDAITEDVEHYIYKISYWMTNLSVAIGALLGGLMYGYSMLLLFLIAACIFLIVLFILYIWLPQDRNQVKQSDDKRHASRYQKLQIMNIFRSYKLVLKDRNYMLLISGFSIIMMGEFSISSYIAIRLKDQFETISIGSYDITGAKMLAILLMINTVVVILLTYSISKVVLKIDFKKALITGLLIYIVGYSGLTYLNQFGLLVVFMIIATVGEIIYSPIVSEQRFKIIPKAKRGTYSAVNALGIHFSETLARLGIVLGVFLTSLQMGLYMFIVLTIGASMLVAGVFGGQKQVNTN
>CP022582.1|AXI04939.1|191946_199140_+|gramicidin-S-synthetase-2-related-protein
MKEGLFMIMGNLRFQQEYFRIYKNNTESTTHRNAYWVKLAKNVEATKMMYALSTIVQQHASIRHFFDVTTDDNLTMILHEFLPFIEIKQVPSSSANYDLEAFFKQELSTYHFNDSPLFKVKLFQFADAAYILLDFHVSIFDDSQIDIFLDDLCNAYRGNTVINNTRQHAHINRNDDKDNQDASHIALDSNYFRLENNSDIHIDSYFPIKHPFEQALYQTYLIDDMTSIDMASLAVSVYLANHIMSQQHDVTLGIHVPSHLPNDLHGNIVPLTLTIDAKDVCQRFTTDFNKCVLQNMSQLQCAKSSLSLETIFHCYHHMMSCCNDVIEDVHQIHDAHTSLADIEIFPHQHGFKIIYNSAAYDLLSIETLSDLVRNIYLQITEENGNKRTTVDELNLMTERDIQLYDDINLSLPEIDDAQTVVTLFEQQVEATPNHVAVQFDGVFITYQTLNARANDLAHRLRNQYGVEPNDRVAVIAEKSIEMIIAMIGVLKAGGAYVPIDPNYPSDRQEYILKDATPKVVITYQALYENGKQNINHIDLNKIAWKNIDNLSKCNTLEDHAYVIYTSGTTGNPKGTLIPHRGIVRLVHRNHYVPLNEETTILLSGTIAFDAATFEIYGALLNGGKLIVAKKEQLLNPIAVEQLINENDVNTMWLTSSLFNQIASERIEVLVPLKYLLIGGEVLNAKWVDLLNQKPKHPQIINGYGPTENTTFTTTYNIPNKVPNRIPIGKPILGTHVYIMQGERRCGVGIPGELCTSGFGLAAGYLNQPELTADKFIKDSNINQLMYRSGDIVRLLPDGNIDYLYRKDKQVKIRGFRIELSEVEHALERIQGINKAVVIVQNHDQDQYIVAYYEAMHTLSHNKIKSQLRMTLPEYMIPVNFMHIEQIPITINGKLDKKALPIMDYVDTDAYVAPSTDTEHLLCQIFADILHVNQVGIHDNFFELGGHSLKATLVVNRIEASTGKRLQIGDLLQKPTVFELAQAIAKVQEQNYEVIPEAIVKDDYVLSSAQKRMYLLWKSNHKDTVYNVPFLWRLSSGLNVAQLQQAVQHLIARHEILRTQYIVVDDEVRQHIVADVVADFEEVNTHFTDEQEIMRQFVAPFNLEKPSQIRVRYIRSPLHAYLFIDTHHIINDGMSNIQLMNDLNALYQHKLLLPLKLQYKDYSEWMSHRDMTKHRQYWLSQFKDEVPILSLPTDYVRPNIKTTNGAMMSFTMNQQMRQLLQKYVEKHQITDFMFFMSVVMTLLSRYARKDDVVVGSVMSARMHKGTEQMLGMFANTLVYRGQPSPDKMWTQFLQEVKEMSLEAYEHQEYPFECLVNDLDQSHDASRNPLFDVMLVLQNNETNHAHFGHSKLTHIQPKSVTAKFDLSFIIEEDRDDYTINIEYNTDLYHSETVRHMGNQCMIMIDYILKHQDTLQICDIPNGTEELLNWVNTHVNDRMLNVPGNKSIISYFNEVVSRQGNHVALVMNDLTMTYETLRNYVDAIAHMLLSNGVGNGQRVALFTERSFEMIAAMLATVKVGASYIPIDIDFPNKRQGAILEDAKVTAVMSYGVEIETTLPVIQLENAKGFVESKENEQYDDLHGNQLENTAMLDNEMYAIYTSGTTGMPKGVAIRQRNLLNLVHAWSTELQLGDNEVFLQHANIVFDASVMEIYCCLLNGHTLVIPDREERVNPEQLQQLINKHRVTVASIPLQMCSIMEDFYIEKLITGGATSTASFVKYIEKHCGTYFNAYGPSESTVITSYWSHHCGDLIPETIPIGKPLSNIQVYIMSDGLLCGIGMPGELCIAGDSLAIGYINRPELMADKWQNNPFGKGKLYHSGDLARYTSDGQIEFLGRIDKQVKVNGYRIELDEIENVILAIRGISDCVVTVSHFDTHDILNAYYVGEQQVEQDLKQYLNDQLPKYMIPKTITHIDCMPLTTNDKVDTTRLPNPSPIQQSNKVYSEPSNEIEQTFVDVFGEVLKQNDVGVDDDFFELGGNSLEAMLVVSHLKRFGHHISMQTLYQYKTVRQIVNYMYQNQQSLVALPDNLSELQKIVMSRYNLGILEDSLSHRPLGNTLLTGATGFLGAYLIEALQGYSHRIYCFIRADNEEIAWYKLMTNLNDYFSEETVEMMLSNIEVIVGDFECMDDVVLPENMDTIIHAGARTDHFGDDDEFEKVNVQGTVDVIRLAQQHHARLIYVSTISVGTYFDIDTEDVTFSEADVYKGQLLTSPYTRSKFYSELKVLEAVNNGLDGRIVRVGNLTSPYNGRWHMRNIKTNRFSMVMNDLLQLDCIGVSMAEMPVDFSFVDTTARQIVALAQVNTPQIIYHVLSPNKMPVKSLLECVKRKEIELVSDESFNEILQKQDMYETIGLTSVDREQQLAMIDTTLTLKIMNHISEKWPTITNNWLYHWAQYIKTIFNK

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Crispr_ID: CP022582_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022582_2

422445-422546

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022582_2

>merge|CP022582|2|422445-422546|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>CP022582|2|2|422445-422546|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
CP022582.1\|AXI05138.1\|412871_413453_+\|phosphoglycerate-mutase-family-protein	unknown	unknown	gnl\|CDD\|223483
CP022582.1\|AXI05147.1\|422562_423519_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
CP022582.1\|AXI05146.1\|420911_422231_+\|zinc-finger-of-transposase-IS204/IS1001/IS1096/IS1165	unknown	unknown	gnl\|CDD\|225995
CP022582.1\|AXI05140.1\|414171_414798_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380196
CP022582.1\|AXI05150.1\|425361_425940_+\|Xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
CP022582.1\|AXI05143.1\|416780_417350_-\|Alkyl-hydroperoxide-reductase-protein-C	unknown	unknown	gnl\|CDD\|211789
CP022582.1\|AXI05149.1\|424441_424849_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378584
CP022582.1\|AXI05137.1\|412484_412694_-\|hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI05153.1\|428736_430278_+\|GMP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|234614
CP022582.1\|AXI05148.1\|423636_424299_-\|hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI05151.1\|425939_427208_+\|Xanthine-permease	unknown	unknown	gnl\|CDD\|274468
CP022582.1\|AXI05139.1\|413518_413902_-\|hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI05154.1\|430345_431539_-\|Integrase,-superantigen-encoding-pathogenicity-islands-SaPI	unknown	unknown	gnl\|CDD\|271189
CP022582.1\|AXI05155.1\|431565_431766_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371495
CP022582.1\|AXI05144.1\|417841_418597_+\|Nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|380322
CP022582.1\|AXI05141.1\|414870_415062_-\|hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI05142.1\|415241_416765_-\|Alkyl-hydroperoxide-reductase-protein-F	unknown	unknown	gnl\|CDD\|237942
CP022582.1\|AXI05152.1\|427245_428712_+\|Inosine-5'-monophosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
CP022582.1\|AXI05145.1\|418676_420065_-\|L-cystine-uptake-protein-TcyP	unknown	unknown	gnl\|CDD\|224736
CP022582.1\|AXI05156.1\|432263_432494_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378900

Protein	Function_ID	Function_description	E-value
CP022582.1\|AXI05138.1\|412871_413453_+\|phosphoglycerate-mutase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.4566e-49
CP022582.1\|AXI05147.1\|422562_423519_-\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00265416
CP022582.1\|AXI05146.1\|420911_422231_+\|zinc-finger-of-transposase-IS204/IS1001/IS1096/IS1165	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.75686e-114
CP022582.1\|AXI05140.1\|414171_414798_-\|hypothetical-protein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.15385e-71
CP022582.1\|AXI05150.1\|425361_425940_+\|Xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
CP022582.1\|AXI05143.1\|416780_417350_-\|Alkyl-hydroperoxide-reductase-protein-C	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
CP022582.1\|AXI05149.1\|424441_424849_-\|hypothetical-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.17298e-12
CP022582.1\|AXI05153.1\|428736_430278_+\|GMP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
CP022582.1\|AXI05151.1\|425939_427208_+\|Xanthine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	2.06593e-169
CP022582.1\|AXI05154.1\|430345_431539_-\|Integrase,-superantigen-encoding-pathogenicity-islands-SaPI	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.36769e-47
CP022582.1\|AXI05155.1\|431565_431766_-\|hypothetical-protein	gnl\|CDD\|371495	pfam11372, DUF3173, Domain of unknown function (DUF3173). This family of proteins with unknown function appears to be restricted to Firmicutes. These proteins appear to be distantly related to HHH domains and are therefore likely to be DNA-binding. Genomic environment-visualisation confirms the likely function as being DNA-binding, as this short protein lies very closely between an integrase and a replication protein (http://www.microbesonline.org/).	2.02242e-22
CP022582.1\|AXI05144.1\|417841_418597_+\|Nitroreductase-family-protein	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	1.09103e-86
CP022582.1\|AXI05142.1\|415241_416765_-\|Alkyl-hydroperoxide-reductase-protein-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
CP022582.1\|AXI05152.1\|427245_428712_+\|Inosine-5'-monophosphate-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
CP022582.1\|AXI05145.1\|418676_420065_-\|L-cystine-uptake-protein-TcyP	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
CP022582.1\|AXI05156.1\|432263_432494_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378900	pfam12645, HTH_16, Helix-turn-helix domain. This domain appears to be a helix-turn-helix domain suggesting that this might be a transcriptional regulatory protein. Some members of this family are annotated as conjugative transposon domains.	2.04673e-25

>CP022582.1|AXI05146.1|420911_422231_+|zinc-finger-of-transposase-IS204/IS1001/IS1096/IS1165
MCNDTLELLRIKDENIKYINQEIDVIIKGKKATVVNAVLTYKPSACYCCGVKNEGQIHKHGKRVSRITLLKTQGYNTYLNLAKQRFKCLECNGTFTAKTSIVDESCFISRCVTQKVIEEATKVKTEIDTAEDNCISPSTVSRIRTKAANSLRIKPFNCLPEHIAMDEFKSVKNVTGSMSFIFIDNDTHDVIDILENRTTRFLRAYFERFDLKNRQQVKTVTIDMYEPYVRLFRDLFPNAAIIFDRFHIVQHLNRELNKYRVQVMNEYRNKKGPNYTIFKNNWKVLLMDTSKTIFSKYRWNKSFKAYKRSSDIVEFMLSKDDILRRSYELVQGLRKDLRLCNWPKFINRLNSVSKKSVSKGVWKVVKYYRKHQRMLRNTIYYPAFNNGAIEGINNKIKLIKRISFGYRNFNNFKARIMMIFSLYKGEKKKTTKPNNGLAA
>CP022582.1|AXI05145.1|418676_420065_-|L-cystine-uptake-protein-TcyP
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLVYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFESNDNAALTSH
>CP022582.1|AXI05144.1|417841_418597_+|Nitroreductase-family-protein
MSDYVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVDENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>CP022582.1|AXI05143.1|416780_417350_-|Alkyl-hydroperoxide-reductase-protein-C
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>CP022582.1|AXI05142.1|415241_416765_-|Alkyl-hydroperoxide-reductase-protein-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDEKSKELKELLTEISDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKNLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMSTGEEHLLNLDGIFVQIGLLPNTSWLKDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>CP022582.1|AXI05141.1|414870_415062_-|hypothetical-protein
MNEIIMLLRTIPTSKLIQPIMQLFIDNAILNIVQNDALLIEKATHARNHLRLWSLQGHRDIPN
>CP022582.1|AXI05140.1|414171_414798_-|hypothetical-protein
MKKRLLLSTFLASALILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>CP022582.1|AXI05139.1|413518_413902_-|hypothetical-protein
MKVRITFIILAILSTIVCLFLAAMYPTGPNTVTFEQPYLFTLNIILMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFISAIITLAIGGKSVDKNDSH
>CP022582.1|AXI05138.1|412871_413453_+|phosphoglycerate-mutase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSREEAVDLKVENCKPYIIE
>CP022582.1|AXI05137.1|412484_412694_-|hypothetical-protein
MTTQSFIFMNIILLDGATQRHPFFICQILAFLFPKFPHINLLLFYPILSTFSNIIIHIDHFHANKKDDN
>CP022582.1|AXI05147.1|422562_423519_-|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKVLAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNENAAETSNKEATVDADAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>CP022582.1|AXI05148.1|423636_424299_-|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>CP022582.1|AXI05149.1|424441_424849_-|hypothetical-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHKEVQEHNSAYEEIDITHFAEASKGPKA
>CP022582.1|AXI05150.1|425361_425940_+|Xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>CP022582.1|AXI05151.1|425939_427208_+|Xanthine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILVLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFILAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>CP022582.1|AXI05152.1|427245_428712_+|Inosine-5'-monophosphate-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>CP022582.1|AXI05153.1|428736_430278_+|GMP-synthase-(glutamine-hydrolyzing)
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>CP022582.1|AXI05154.1|430345_431539_-|Integrase,-superantigen-encoding-pathogenicity-islands-SaPI
MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEAREEYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFDKMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGNVKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDIDFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQTDFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDRLGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKEMKKVQ
>CP022582.1|AXI05155.1|431565_431766_-|hypothetical-protein
MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLDRVPREAVEEILGIRFSNENRSE
>CP022582.1|AXI05156.1|432263_432494_-|helix-turn-helix-domain-containing-protein
MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMTDEYGNSHMVIDETLRGRMETKLISKILSFEIK

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Crispr_ID: CP022582_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022582_3

798593-798675

Orphan

Consensus_repeat	Method
CCAATTTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022582_3

>merge|CP022582|3|798593-798675|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACATAGAGAAATTGGAACGCCAATTTCTACAGACAATGCAAGTTGG

>CP022582|3|3|798593-798675|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACATAGAGAAATTGGAACG
CCAATTTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
CP022582.1\|AXI05483.1\|796504_797563_+\|Biosynthetic-Aromatic-amino-acid-aminotransferase-beta	unknown	unknown	gnl\|CDD\|235106
CP022582.1\|AXI05479.1\|789888_791766_+\|ATPase-components-of-ABC-transporters-with-duplicated-ATPase-domains	unknown	unknown	gnl\|CDD\|223562
CP022582.1\|AXI05475.1\|784532_785141_+\|Aminodeoxychorismate-lyase	unknown	unknown	gnl\|CDD\|376449
CP022582.1\|AXI05490.1\|804903_807009_+\|Ribonucleotide-reductase-of-class-Ib(aerobic)-alpha-subunit	unknown	unknown	gnl\|CDD\|236069
CP022582.1\|AXI05481.1\|793780_794758_+\|Glycine-betaine-ABC-transport-system,-ATP-binding-protein-OpuAA	unknown	unknown	gnl\|CDD\|224050
CP022582.1\|AXI05488.1\|802875_803742_-\|Integral-membrane-domain-protein	unknown	unknown	gnl\|CDD\|223769
CP022582.1\|AXI05476.1\|785500_786211_+\|Allophanate-hydrolase-2-subunit-1	unknown	unknown	gnl\|CDD\|224960
CP022582.1\|AXI05486.1\|800509_802015_-\|Di/tripeptide-permease-YjdL	unknown	unknown	gnl\|CDD\|225646
CP022582.1\|AXI05482.1\|794750_796265_+\|L-proline-glycine-betaine-binding-ABC-transporter-protein-ProX	unknown	unknown	gnl\|CDD\|270328
CP022582.1\|AXI05492.1\|808472_809444_+\|Iron-compound-ABC-uptake-transporter-permease-protein	unknown	unknown	gnl\|CDD\|226965
CP022582.1\|AXI05478.1\|787672_789613_+\|Lipoteichoic-acid-synthase-LtaS-Type-Ia	unknown	unknown	gnl\|CDD\|224287
CP022582.1\|AXI05477.1\|786194_787199_+\|Allophanate-hydrolase-2-subunit-2	unknown	unknown	gnl\|CDD\|224895
CP022582.1\|AXI05491.1\|807126_808098_+\|Ribonucleotide-reductase-of-class-Ib(aerobic)-beta-subunit	unknown	unknown	gnl\|CDD\|275027
CP022582.1\|AXI05484.1\|797901_798444_+\|5'-3'-deoxyribonucleotidase	unknown	unknown	gnl\|CDD\|226895
CP022582.1\|AXI05487.1\|802355_802856_-\|NADPH-dependent-preQ0-reductase	unknown	unknown	gnl\|CDD\|223851
CP022582.1\|AXI05494.1\|810383_811145_+\|Iron-compound-ABC-uptake-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226963
CP022582.1\|AXI05480.1\|791777_793559_+\|ATP-dependent-DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|273594
CP022582.1\|AXI05489.1\|804542_804941_+\|Ribonucleotide-reduction-protein-NrdI	unknown	unknown	gnl\|CDD\|224694
CP022582.1\|AXI05485.1\|799322_800240_-\|Transcription-regulator	unknown	unknown	gnl\|CDD\|224513
CP022582.1\|AXI05493.1\|809430_810387_+\|Iron-compound-ABC-uptake-transporter-permease-protein	unknown	unknown	gnl\|CDD\|226964

Protein	Function_ID	Function_description	E-value
CP022582.1\|AXI05483.1\|796504_797563_+\|Biosynthetic-Aromatic-amino-acid-aminotransferase-beta	gnl\|CDD\|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0
CP022582.1\|AXI05479.1\|789888_791766_+\|ATPase-components-of-ABC-transporters-with-duplicated-ATPase-domains	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
CP022582.1\|AXI05475.1\|784532_785141_+\|Aminodeoxychorismate-lyase	gnl\|CDD\|376449	pfam01063, Aminotran_4, Amino-transferase class IV. The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.	5.60043e-39
CP022582.1\|AXI05490.1\|804903_807009_+\|Ribonucleotide-reductase-of-class-Ib(aerobic)-alpha-subunit	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
CP022582.1\|AXI05481.1\|793780_794758_+\|Glycine-betaine-ABC-transport-system,-ATP-binding-protein-OpuAA	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	1.28246e-155
CP022582.1\|AXI05488.1\|802875_803742_-\|Integral-membrane-domain-protein	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.04233e-10
CP022582.1\|AXI05476.1\|785500_786211_+\|Allophanate-hydrolase-2-subunit-1	gnl\|CDD\|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	1.34598e-94
CP022582.1\|AXI05486.1\|800509_802015_-\|Di/tripeptide-permease-YjdL	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.22605e-172
CP022582.1\|AXI05482.1\|794750_796265_+\|L-proline-glycine-betaine-binding-ABC-transporter-protein-ProX	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.03165e-152
CP022582.1\|AXI05492.1\|808472_809444_+\|Iron-compound-ABC-uptake-transporter-permease-protein	gnl\|CDD\|226965	COG4606, CeuB, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	1.32603e-150
CP022582.1\|AXI05478.1\|787672_789613_+\|Lipoteichoic-acid-synthase-LtaS-Type-Ia	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
CP022582.1\|AXI05477.1\|786194_787199_+\|Allophanate-hydrolase-2-subunit-2	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.25641e-144
CP022582.1\|AXI05491.1\|807126_808098_+\|Ribonucleotide-reductase-of-class-Ib(aerobic)-beta-subunit	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.30551e-164
CP022582.1\|AXI05484.1\|797901_798444_+\|5'-3'-deoxyribonucleotidase	gnl\|CDD\|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	3.14113e-108
CP022582.1\|AXI05487.1\|802355_802856_-\|NADPH-dependent-preQ0-reductase	gnl\|CDD\|223851	COG0780, COG0780, Enzyme related to GTP cyclohydrolase I [General function prediction only].	7.91282e-79
CP022582.1\|AXI05494.1\|810383_811145_+\|Iron-compound-ABC-uptake-transporter-ATP-binding-protein	gnl\|CDD\|226963	COG4604, CeuD, ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism].	1.22383e-150
CP022582.1\|AXI05480.1\|791777_793559_+\|ATP-dependent-DNA-helicase-RecQ	gnl\|CDD\|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
CP022582.1\|AXI05489.1\|804542_804941_+\|Ribonucleotide-reduction-protein-NrdI	gnl\|CDD\|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	5.52807e-56
CP022582.1\|AXI05485.1\|799322_800240_-\|Transcription-regulator	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	7.55646e-79
CP022582.1\|AXI05493.1\|809430_810387_+\|Iron-compound-ABC-uptake-transporter-permease-protein	gnl\|CDD\|226964	COG4605, CeuC, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	4.81847e-122

>CP022582.1|AXI05484.1|797901_798444_+|5'-3'-deoxyribonucleotidase
MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPHAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
>CP022582.1|AXI05483.1|796504_797563_+|Biosynthetic-Aromatic-amino-acid-aminotransferase-beta
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>CP022582.1|AXI05482.1|794750_796265_+|L-proline-glycine-betaine-binding-ABC-transporter-protein-ProX
MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILLTKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRFMAKLSYKKLLMTLGVIVMIIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMKYNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNLDNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKESFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK
>CP022582.1|AXI05481.1|793780_794758_+|Glycine-betaine-ABC-transport-system,-ATP-binding-protein-OpuAA
MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTLKMINRLIHLSEGYIYFKDKPISDYPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQMKKWKEKDIDKRVDELLDMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMDEPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQIDTPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTSMSAYPIVYDNQPIEVLYQHLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD
>CP022582.1|AXI05480.1|791777_793559_+|ATP-dependent-DNA-helicase-RecQ
MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYFLNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVEELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
>CP022582.1|AXI05479.1|789888_791766_+|ATPase-components-of-ABC-transporters-with-duplicated-ATPase-domains
MEAYKIEHLNKSYADKTIFDNLDLSISEGEKIGLVGINGTGKSTLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQYEQAVQAYADDQSDKLFKRMIDAQDAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKELSGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYFLNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAGAKARTTKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKVLFEHLTEIIQKGERIGVVGPNGAGKTTLLNILSGEDQQFEGKLKTGQTVKVAYFKQTDETLDRDIRMIDYLREESEVAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKRLYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQSYWFIHDGQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSYTTVRKKNGLSYKEKLEYEQLMKRIEQAEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIKEQQ
>CP022582.1|AXI05478.1|787672_789613_+|Lipoteichoic-acid-synthase-LtaS-Type-Ia
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
>CP022582.1|AXI05477.1|786194_787199_+|Allophanate-hydrolase-2-subunit-2
MSIIIEKSGLFSSFQDFGRRGYEHDGVIPCGALDTLAHEIANRLVANDKNEATLEMTNKMATIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLKFRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTARHHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVVKNKGTEDFKEDAIQRFVKHDYKVTSKANRMGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQIGTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
>CP022582.1|AXI05476.1|785500_786211_+|Allophanate-hydrolase-2-subunit-1
MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIEIVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYGSKYGPDIESLLKHYKIKLETFIELHSKTQYFVSMMGYSPGFPYLTGLNKKLYINHTSKQKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFRPINENELEVGAFKDVNHN
>CP022582.1|AXI05475.1|784532_785141_+|Aminodeoxychorismate-lyase
MQLFETMKIDNGHIPRLTYHTNRIKCSSERLNFKFDEHAWRNELNDVTTKYHSGQYRLKIVLNAESKFETIVSPLPEKSSFTAKFQVLPKVVNPTFIKNKTTERKHLAHNHETDLILLTSEDGKVLEFDIGNIVIEEDGKWYTPSYKDDFLKGCMRDYLIDSDKLVEKDFNKNELIYKYHNNEIRLFLINSLREVADVHLCL
>CP022582.1|AXI05485.1|799322_800240_-|Transcription-regulator
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMSHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>CP022582.1|AXI05486.1|800509_802015_-|Di/tripeptide-permease-YjdL
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>CP022582.1|AXI05487.1|802355_802856_-|NADPH-dependent-preQ0-reductase
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
>CP022582.1|AXI05488.1|802875_803742_-|Integral-membrane-domain-protein
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFFLYKYHQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSSREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFVLFGESPDFYATLGYVVIIGASYYMFEKARRDAKIIKK
>CP022582.1|AXI05489.1|804542_804941_+|Ribonucleotide-reduction-protein-NrdI
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>CP022582.1|AXI05490.1|804903_807009_+|Ribonucleotide-reductase-of-class-Ib(aerobic)-alpha-subunit
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSISFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
>CP022582.1|AXI05491.1|807126_808098_+|Ribonucleotide-reductase-of-class-Ib(aerobic)-beta-subunit
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK
>CP022582.1|AXI05492.1|808472_809444_+|Iron-compound-ABC-uptake-transporter-permease-protein
MKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNILFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFPTGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGLSYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGAIFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ
>CP022582.1|AXI05493.1|809430_810387_+|Iron-compound-ABC-uptake-transporter-permease-protein
MRNNNKKIMLLIAVTLLISMLYLFVGIDFEIFEYQFSSRLRKFILIILVGAAIATSVVIFQAITNNRLLTPSIMGLDAVYLFIKVLPVFLFGIQSVWVTNVYLNFILTLITMVLFALILFQGIFKIGHFSIYFILLIGVLLGTFFRSITGFIQLIMDPESFLAIQSSMFANFNASNSNLVTFSAVLLVILLVITILLLPYLDVLLLGRAEAINLGISYEKLTRILLVIVSVLVSVSTALVGPITFLGLLTVNLAHELMKTYEHKYILIATICLSWISLFSAQWVVENVFEATTEMSILIDLIGGSYFIYLLVRRRNAQ
>CP022582.1|AXI05494.1|810383_811145_+|Iron-compound-ABC-uptake-transporter-ATP-binding-protein
MIQVENLTKTINNQMILEDISIDIEKGKLTSLIGPNGAGKSTLLSAICRLIRFDNGEVKIDGQLMSDYKNNDLSKKISILKQTNHTEMNITVEQLVNFGRFPYSKGRLTKEDHDIVNDALDLLQLQDIRNRNIKSLSGGQRQRAYIAMTIAQDTEYILLDEPLNNLDMKHAVQIMQTLKMLAHKMNKAIVIVLHDINFASCYSDQIVALKNGQLVKSDLKDNVIQSSVLSDLYDMNIQIEHIRNQRICLYFKD

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Crispr_ID: CP022582_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022582_4

839540-839618

Unclear

Consensus_repeat	Method
TGTAGAATTTCTTTTCGAAATTCT	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of CP022582_4

>merge|CP022582|4|839540-839618|CRISPRCasFinder
TGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCGCCAACTTGCATTGCCTGTAGAATTTCTTTTCGAAATTCT

>CP022582|4|4|839540-839618|CRISPRCasFinder
TGTAGAATTTCTTTTCGAAATTCT	CTGTGTTGGGGCCCCGCCAACTTGCATTGCC
TGTAGAATTTCTTTTCGAAATTCT

Protein	Signature genes	Signature genes Name	Protein_function
CP022582.1\|AXI05524.1\|844942_845230_-\|hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI05528.1\|848945_849533_+\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|178955
CP022582.1\|AXI05512.1\|827843_830375_+\|Protein-export-cytoplasm-protein-SecA-ATPase-RNA-helicase	unknown	unknown	gnl\|CDD\|237259
CP022582.1\|AXI05517.1\|834373_836359_+\|Excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
CP022582.1\|AXI05526.1\|846331_847327_+\|LPPG:FO-2-phospho-L-lactate-transferase-like,-CofD-like	unknown	unknown	gnl\|CDD\|211689
CP022582.1\|AXI05525.1\|845423_846335_+\|Hypothetical-ATP-binding-protein-UPF0042,-contains-P-loop	unknown	unknown	gnl\|CDD\|224574
CP022582.1\|AXI05522.1\|842154_843594_+\|TPR-domain-protein	unknown	unknown	gnl\|CDD\|276808
CP022582.1\|AXI05511.1\|826857_827430_+\|Ribosomal-subunit-interface-protein	unknown	unknown	gnl\|CDD\|224461
CP022582.1\|AXI05515.1\|833221_833872_+\|Nucleotidase-YfbR,-HD-superfamily	unknown	unknown	gnl\|CDD\|378993
CP022582.1\|AXI05513.1\|830807_831800_+\|Peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
CP022582.1\|AXI05516.1\|833868_834105_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227234
CP022582.1\|AXI05519.1\|839876_840809_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
CP022582.1\|AXI05521.1\|841865_842147_+\|Putative-acetyltransferase-YvoF	unknown	unknown	gnl\|CDD\|100047
CP022582.1\|AXI05518.1\|836366_839213_+\|Excinuclease-ABC-subunit-A	unknown	unknown	gnl\|CDD\|234734
CP022582.1\|AXI05527.1\|847437_848382_+\|Cytoplasmic-hypothetical-protein	unknown	unknown	gnl\|CDD\|273194
CP022582.1\|AXI05520.1\|840814_841654_+\|Prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
CP022582.1\|AXI05523.1\|843660_844596_+\|Thioredoxin-reductase	unknown	unknown	gnl\|CDD\|273540
CP022582.1\|AXI05510.1\|826122_826797_+\|competence-protein-ComF	unknown	unknown	gnl\|CDD\|223970
CP022582.1\|AXI05514.1\|832208_833048_+\|LysM-domain-protein	unknown	unknown	gnl\|CDD\|226451
CP022582.1\|AXI05509.1\|825176_826130_+\|Type-III-restriction-enzyme,-res-subunit	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|226583

Protein	Function_ID	Function_description	E-value
CP022582.1\|AXI05528.1\|848945_849533_+\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
CP022582.1\|AXI05512.1\|827843_830375_+\|Protein-export-cytoplasm-protein-SecA-ATPase-RNA-helicase	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
CP022582.1\|AXI05517.1\|834373_836359_+\|Excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP022582.1\|AXI05526.1\|846331_847327_+\|LPPG:FO-2-phospho-L-lactate-transferase-like,-CofD-like	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
CP022582.1\|AXI05525.1\|845423_846335_+\|Hypothetical-ATP-binding-protein-UPF0042,-contains-P-loop	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
CP022582.1\|AXI05522.1\|842154_843594_+\|TPR-domain-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
CP022582.1\|AXI05511.1\|826857_827430_+\|Ribosomal-subunit-interface-protein	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
CP022582.1\|AXI05515.1\|833221_833872_+\|Nucleotidase-YfbR,-HD-superfamily	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
CP022582.1\|AXI05513.1\|830807_831800_+\|Peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
CP022582.1\|AXI05516.1\|833868_834105_+\|hypothetical-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
CP022582.1\|AXI05519.1\|839876_840809_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
CP022582.1\|AXI05521.1\|841865_842147_+\|Putative-acetyltransferase-YvoF	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.13458e-26
CP022582.1\|AXI05518.1\|836366_839213_+\|Excinuclease-ABC-subunit-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP022582.1\|AXI05527.1\|847437_848382_+\|Cytoplasmic-hypothetical-protein	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
CP022582.1\|AXI05520.1\|840814_841654_+\|Prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.75588e-120
CP022582.1\|AXI05523.1\|843660_844596_+\|Thioredoxin-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
CP022582.1\|AXI05510.1\|826122_826797_+\|competence-protein-ComF	gnl\|CDD\|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	1.0058e-51
CP022582.1\|AXI05514.1\|832208_833048_+\|LysM-domain-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.97111e-42
CP022582.1\|AXI05509.1\|825176_826130_+\|Type-III-restriction-enzyme,-res-subunit	gnl\|CDD\|226583	COG4098, comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair].	1.05277e-176

>CP022582.1|AXI05518.1|836366_839213_+|Excinuclease-ABC-subunit-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDELTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>CP022582.1|AXI05517.1|834373_836359_+|Excinuclease-ABC-subunit-B
MVEHYPFKIHSDFEPQGDQPQAIKEIVDGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>CP022582.1|AXI05516.1|833868_834105_+|hypothetical-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>CP022582.1|AXI05515.1|833221_833872_+|Nucleotidase-YfbR,-HD-superfamily
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>CP022582.1|AXI05514.1|832208_833048_+|LysM-domain-protein
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>CP022582.1|AXI05513.1|830807_831800_+|Peptide-chain-release-factor-2
MAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>CP022582.1|AXI05512.1|827843_830375_+|Protein-export-cytoplasm-protein-SecA-ATPase-RNA-helicase
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>CP022582.1|AXI05511.1|826857_827430_+|Ribosomal-subunit-interface-protein
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>CP022582.1|AXI05510.1|826122_826797_+|competence-protein-ComF
MNNCLSCGAKLYENITIYNLFKKPNRLCDRCKENWDNIKLDIKARRCSRCLKHLNQDEAYCLDCKFLSAHFNLMEQLYCQFQYDGLMKEMIHQYKFLKDYYLCELLAHLIEIPQTSYDYIVPIPSSPAHDLSRTFNPVEAVLKAKGIRFDKILKMSNRPKQSHLTKKERLADENPFIIDTELDLNGKEILLVDDIYTTGLTIHRAGCKLYAKNIRKFKVFAFAR
>CP022582.1|AXI05509.1|825176_826130_+|Type-III-restriction-enzyme,-res-subunit
MRQTILLYAVTGAGKTEMMFQGIQYARRQGDNIAIVSPRVDVVVEISKRIKDAFLNEDIDILHQQSSQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKSLQQALKSSSKVEHATIYMTATPPKQLLSEIPHENIIKLPARFHKKSLPVPKYRYFKLNNNKIQKMLYRILQDQINNQRYTLVFFNNIETMIKTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKLECPAGKVLFFHEGVSMNMIQAKKEIQRMNKLALKRGWIDE
>CP022582.1|AXI05519.1|839876_840809_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>CP022582.1|AXI05520.1|840814_841654_+|Prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>CP022582.1|AXI05521.1|841865_842147_+|Putative-acetyltransferase-YvoF
MLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP022582.1|AXI05522.1|842154_843594_+|TPR-domain-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP022582.1|AXI05523.1|843660_844596_+|Thioredoxin-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>CP022582.1|AXI05524.1|844942_845230_-|hypothetical-protein
MKMRLQQAFFNSSQGPQHREIGFPISTDNASWGVGPNTEKLDFQFLQTMQVGVWAPTKRISKRNSTGNASWGVGPNTEAYDKSAYDNVQVGVVQR
>CP022582.1|AXI05525.1|845423_846335_+|Hypothetical-ATP-binding-protein-UPF0042,-contains-P-loop
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>CP022582.1|AXI05526.1|846331_847327_+|LPPG:FO-2-phospho-L-lactate-transferase-like,-CofD-like
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>CP022582.1|AXI05527.1|847437_848382_+|Cytoplasmic-hypothetical-protein
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>CP022582.1|AXI05528.1|848945_849533_+|ATP-dependent-Clp-protease-proteolytic-subunit
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK

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Crispr_ID: CP022582_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022582_6

852251-852330

Orphan

Consensus_repeat	Method
CAGCTTCTGTGTTGGGGCCCCGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022582_6

>merge|CP022582|6|852251-852330|CRISPRCasFinder
CAGCTTCTGTGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTGTGTTGGGGCCCCACC

>CP022582|6|5|852251-852330|CRISPRCasFinder
CAGCTTCTGTGTTGGGGCCCCGCC	AACTTGCACATTATTGTAAGCTGACTTTCCGC
CAGCTTCTGTGTTGGGGCCCCACC

Protein	Signature genes	Signature genes Name	Protein_function
CP022582.1\|AXI05528.1\|848945_849533_+\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|178955
CP022582.1\|AXI05524.1\|844942_845230_-\|hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI05539.1\|861221_861962_+\|Carboxylesterase	unknown	unknown	gnl\|CDD\|224561
CP022582.1\|AXI05536.1\|858704_860009_+\|Enolase	unknown	unknown	gnl\|CDD\|234617
CP022582.1\|AXI05526.1\|846331_847327_+\|LPPG:FO-2-phospho-L-lactate-transferase-like,-CofD-like	unknown	unknown	gnl\|CDD\|211689
CP022582.1\|AXI05540.1\|861995_864368_+\|3'-to-5'-exoribonuclease-RNase-R	unknown	unknown	gnl\|CDD\|273947
CP022582.1\|AXI05531.1\|852766_853780_+\|glycolytic-regulator	unknown	unknown	gnl\|CDD\|225263
CP022582.1\|AXI05538.1\|860872_861106_+\|Preprotein-translocase-subunit-SecG	unknown	unknown	gnl\|CDD\|224233
CP022582.1\|AXI05532.1\|853832_854843_+\|NAD-dependent-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
CP022582.1\|AXI05537.1\|860347_860806_+\|hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI05529.1\|849775_850678_-\|Cell-division-inhibitor	unknown	unknown	gnl\|CDD\|224015
CP022582.1\|AXI05521.1\|841865_842147_+\|Putative-acetyltransferase-YvoF	unknown	unknown	gnl\|CDD\|100047
CP022582.1\|AXI05525.1\|845423_846335_+\|Hypothetical-ATP-binding-protein-UPF0042,-contains-P-loop	unknown	unknown	gnl\|CDD\|224574
CP022582.1\|AXI05527.1\|847437_848382_+\|Cytoplasmic-hypothetical-protein	unknown	unknown	gnl\|CDD\|273194
CP022582.1\|AXI05534.1\|856293_857055_+\|Triosephosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
CP022582.1\|AXI05533.1\|854981_856172_+\|Phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
CP022582.1\|AXI05523.1\|843660_844596_+\|Thioredoxin-reductase	unknown	unknown	gnl\|CDD\|273540
CP022582.1\|AXI05522.1\|842154_843594_+\|TPR-domain-protein	unknown	unknown	gnl\|CDD\|276808
CP022582.1\|AXI05530.1\|851380_852010_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234750
CP022582.1\|AXI05535.1\|857057_858575_+\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|235463

Protein	Function_ID	Function_description	E-value
CP022582.1\|AXI05528.1\|848945_849533_+\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
CP022582.1\|AXI05539.1\|861221_861962_+\|Carboxylesterase	gnl\|CDD\|224561	COG1647, COG1647, Esterase/lipase [General function prediction only].	1.30175e-132
CP022582.1\|AXI05536.1\|858704_860009_+\|Enolase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
CP022582.1\|AXI05526.1\|846331_847327_+\|LPPG:FO-2-phospho-L-lactate-transferase-like,-CofD-like	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
CP022582.1\|AXI05531.1\|852766_853780_+\|glycolytic-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92
CP022582.1\|AXI05538.1\|860872_861106_+\|Preprotein-translocase-subunit-SecG	gnl\|CDD\|224233	COG1314, SecG, Preprotein translocase subunit SecG [Intracellular trafficking and secretion].	6.41939e-15
CP022582.1\|AXI05532.1\|853832_854843_+\|NAD-dependent-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
CP022582.1\|AXI05540.1\|861995_864368_+\|3'-to-5'-exoribonuclease-RNase-R	gnl\|CDD\|273947	TIGR02063, Ribonuclease_R, ribonuclease R. This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA].	0
CP022582.1\|AXI05529.1\|849775_850678_-\|Cell-division-inhibitor	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	6.73087e-155
CP022582.1\|AXI05521.1\|841865_842147_+\|Putative-acetyltransferase-YvoF	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.13458e-26
CP022582.1\|AXI05525.1\|845423_846335_+\|Hypothetical-ATP-binding-protein-UPF0042,-contains-P-loop	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
CP022582.1\|AXI05527.1\|847437_848382_+\|Cytoplasmic-hypothetical-protein	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
CP022582.1\|AXI05534.1\|856293_857055_+\|Triosephosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.84083e-146
CP022582.1\|AXI05533.1\|854981_856172_+\|Phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
CP022582.1\|AXI05523.1\|843660_844596_+\|Thioredoxin-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
CP022582.1\|AXI05522.1\|842154_843594_+\|TPR-domain-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
CP022582.1\|AXI05530.1\|851380_852010_+\|hypothetical-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.80381e-05
CP022582.1\|AXI05535.1\|857057_858575_+\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	gnl\|CDD\|235463	PRK05434, PRK05434, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.	0

>CP022582.1|AXI05530.1|851380_852010_+|hypothetical-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDNASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>CP022582.1|AXI05529.1|849775_850678_-|Cell-division-inhibitor
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>CP022582.1|AXI05528.1|848945_849533_+|ATP-dependent-Clp-protease-proteolytic-subunit
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>CP022582.1|AXI05527.1|847437_848382_+|Cytoplasmic-hypothetical-protein
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>CP022582.1|AXI05526.1|846331_847327_+|LPPG:FO-2-phospho-L-lactate-transferase-like,-CofD-like
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>CP022582.1|AXI05525.1|845423_846335_+|Hypothetical-ATP-binding-protein-UPF0042,-contains-P-loop
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>CP022582.1|AXI05524.1|844942_845230_-|hypothetical-protein
MKMRLQQAFFNSSQGPQHREIGFPISTDNASWGVGPNTEKLDFQFLQTMQVGVWAPTKRISKRNSTGNASWGVGPNTEAYDKSAYDNVQVGVVQR
>CP022582.1|AXI05523.1|843660_844596_+|Thioredoxin-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>CP022582.1|AXI05522.1|842154_843594_+|TPR-domain-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP022582.1|AXI05521.1|841865_842147_+|Putative-acetyltransferase-YvoF
MLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP022582.1|AXI05531.1|852766_853780_+|glycolytic-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>CP022582.1|AXI05532.1|853832_854843_+|NAD-dependent-glyceraldehyde-3-phosphate-dehydrogenase
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>CP022582.1|AXI05533.1|854981_856172_+|Phosphoglycerate-kinase
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>CP022582.1|AXI05534.1|856293_857055_+|Triosephosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK
>CP022582.1|AXI05535.1|857057_858575_+|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase
MAKKPTALIILDGFANRESEHGNAVKLANKPNFDRYYNKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIAHVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVYVHAFLDGRDVDQKSALKYIEETEAKFNELGIGQFASVSGRYYAMDRDKRWEREEKAYNAIRNFDAPTYATAKEGVEASYNEGLTDEFVVPFIVENQNDGVNDGDTVIFYNFRPDRAAQLSEIFANRAFEGFKVEQVKDLFYATFTKYNDNIDAAIVFEKVDLNNTIGEIAQNNNLTQLRIAETEKYPHVTYFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELNKGDLDLIILNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQVLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLIKH
>CP022582.1|AXI05536.1|858704_860009_+|Enolase
MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLDK
>CP022582.1|AXI05537.1|860347_860806_+|hypothetical-protein
MADRTNKEIKTGRFIATASIVFSILLIIHYFVSLDNATAKALLNLTNQNTSDKAIDYILNSFRFTGIMYILAYLAGFITFWNRHTYVWWFMFAVYVSNSLFTLINLSITIQAIKAAHGAYLTLPILIVIIGSVALAIYMLVVSIKRKSTFNR
>CP022582.1|AXI05538.1|860872_861106_+|Preprotein-translocase-subunit-SecG
MHTFLIVLLIIDCIALITVVLLQEGKSSGLSGAISGGAEQLFGKQKQRGVDLFLNRLTIILSILFFVLMICISYLGM
>CP022582.1|AXI05539.1|861221_861962_+|Carboxylesterase
MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPQYEGHAAPPEEILKSSPFVWFKDALDGYDYLVEQGYDEIVVAGLSLGGDFALKLSLNRDVKGIVTMCAPMGGKTEGAIYEGFLEYARNFKKYEGKNQETIDNEMDHFKPTETLKELSEALDTIKDQVDEVFDPILVIQVENDNMIDPQSANYIYDHVDSDDKDIKWYSQSGHVITIDKEKEQVFEDIYQFLESLDWSE
>CP022582.1|AXI05540.1|861995_864368_+|3'-to-5'-exoribonuclease-RNase-R
MNLKQSIEEIINQPEYEPMSVSDFQDALGLSSADSFRDLIKVLVELEQSGLIERTKTDRYQKKHSSKGHSKLIKGTLSQNKKGFAFLRPEDEDMEDIFIPPTKINRALDGDTVIVEIHQSKGEHKGKIEGEVKSIEKHSVTQVVGTYSEARHFGFVIPDDKRIMQDIFIPKGQSLGAVDGHKVLVQITKYADGSDNPEGHISAILGHKNDPGVDILSIIYQHGIEIEFPDEVLQEAEAVPDHIENTEIKGRHDLRDELTITIDGADAKDLDDAISVKKLANGNTQLTVSIADVSYYVTEDSALDKEAYDRATSVYLVDRVIPMIPHRLSNGICSLNPHVDRLTLSCRMEIDASGRVVKHEIFDSVIHSDYRMTYDAVNQIITEKDPNIREQYKEITPMLDLAQDLSNRLIQMRKRRGEIDFDISEAKVLVNEVGIPTDVQLRQRGEGERLIESFMLIANETVAEHFSKLNVPFIYRVHEQPKSDRLRQFFDFITNFGIMIKGTGEDIHPTTLQKVQEEVEGRPEQMVISTMMLRSMQQAHYDDVNLGHFGLSAEYYTHFTSPIRRYPDLTVHRLIRKYLIEKSMDNKEVKRWEDKLPELAEHTSKRERRAIEVERDTDELKKAEYMIQHIGDEFEGIVSSVANFGMFIELPNTIEGMVHIANMTDDYYRFEERQMALIGERQAKVFRIGDTVKVKVTHVDVDERLIDFQIVGMPLPKNDRSQRPARGKTIQAKTRGKSLDKSKSDDKGRKKKGKQRKGKNQRNNDKSGNSKHKPFYKDKSVKKKARRKKK

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Crispr_ID: CP022582_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022582_7

888152-888233

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022582_7

>merge|CP022582|7|888152-888233|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGAGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>CP022582|7|6|888152-888233|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGAGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP022582.1\|AXI05570.1\|888844_889231_+\|Toprim-domain-protein	unknown	unknown	gnl\|CDD\|224572
CP022582.1\|AXI05563.1\|883573_883996_-\|Organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
CP022582.1\|AXI05578.1\|895141_896449_+\|Iron-sulfur-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
CP022582.1\|AXI05564.1\|884143_884860_+\|3-dehydroquinate-dehydratase-I	unknown	unknown	gnl\|CDD\|184156
CP022582.1\|AXI05566.1\|885632_885953_-\|Thioredoxin	unknown	unknown	gnl\|CDD\|239245
CP022582.1\|AXI05561.1\|881908_882526_-\|Transporter,-LysE-family	unknown	unknown	gnl\|CDD\|224198
CP022582.1\|AXI05571.1\|889223_889520_+\|Thioredoxin	unknown	unknown	gnl\|CDD\|239245
CP022582.1\|AXI05560.1\|881254_881836_+\|Phosphoglycerate-mutase-family	unknown	unknown	gnl\|CDD\|223483
CP022582.1\|AXI05574.1\|891500_892322_+\|Methionine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
CP022582.1\|AXI05562.1\|882680_883175_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372596
CP022582.1\|AXI05569.1\|887169_888048_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226395
CP022582.1\|AXI05579.1\|896563_897805_+\|SulS-subfamily-cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
CP022582.1\|AXI05565.1\|884942_885482_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
CP022582.1\|AXI05568.1\|886610_886991_+\|Glycine-cleavage-system-H-protein	unknown	unknown	gnl\|CDD\|234918
CP022582.1\|AXI05567.1\|886096_886453_+\|Arsenate-reductase	unknown	unknown	gnl\|CDD\|239334
CP022582.1\|AXI05576.1\|893103_893955_-\|membrane-protein	unknown	unknown	gnl\|CDD\|224946
CP022582.1\|AXI05573.1\|890787_891483_+\|Methionine-ABC-transporter-permease-protein	unknown	unknown	gnl\|CDD\|224922
CP022582.1\|AXI05572.1\|889769_890795_+\|Methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
CP022582.1\|AXI05577.1\|894282_895044_+\|Iron-sulfur-cluster-assembly-ATPase-protein-SufC	unknown	unknown	gnl\|CDD\|223473
CP022582.1\|AXI05575.1\|892675_892870_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225777

Protein	Function_ID	Function_description	E-value
CP022582.1\|AXI05570.1\|888844_889231_+\|Toprim-domain-protein	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
CP022582.1\|AXI05563.1\|883573_883996_-\|Organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
CP022582.1\|AXI05578.1\|895141_896449_+\|Iron-sulfur-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	3.36148e-135
CP022582.1\|AXI05564.1\|884143_884860_+\|3-dehydroquinate-dehydratase-I	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	3.2619e-146
CP022582.1\|AXI05566.1\|885632_885953_-\|Thioredoxin	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.4922e-24
CP022582.1\|AXI05561.1\|881908_882526_-\|Transporter,-LysE-family	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	2.60719e-61
CP022582.1\|AXI05571.1\|889223_889520_+\|Thioredoxin	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
CP022582.1\|AXI05560.1\|881254_881836_+\|Phosphoglycerate-mutase-family	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	5.2875e-48
CP022582.1\|AXI05574.1\|891500_892322_+\|Methionine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	1.02861e-112
CP022582.1\|AXI05562.1\|882680_883175_-\|hypothetical-protein	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
CP022582.1\|AXI05569.1\|887169_888048_+\|hypothetical-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	3.13065e-77
CP022582.1\|AXI05579.1\|896563_897805_+\|SulS-subfamily-cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
CP022582.1\|AXI05565.1\|884942_885482_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
CP022582.1\|AXI05568.1\|886610_886991_+\|Glycine-cleavage-system-H-protein	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	9.01516e-70
CP022582.1\|AXI05567.1\|886096_886453_+\|Arsenate-reductase	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
CP022582.1\|AXI05576.1\|893103_893955_-\|membrane-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	7.67366e-77
CP022582.1\|AXI05573.1\|890787_891483_+\|Methionine-ABC-transporter-permease-protein	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	7.66296e-99
CP022582.1\|AXI05572.1\|889769_890795_+\|Methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	1.76735e-170
CP022582.1\|AXI05577.1\|894282_895044_+\|Iron-sulfur-cluster-assembly-ATPase-protein-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
CP022582.1\|AXI05575.1\|892675_892870_+\|hypothetical-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07

>CP022582.1|AXI05569.1|887169_888048_+|hypothetical-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLSQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLNDLPEQQELFPVNEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQVHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>CP022582.1|AXI05568.1|886610_886991_+|Glycine-cleavage-system-H-protein
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQLEALLTAEKYSEMIGE
>CP022582.1|AXI05567.1|886096_886453_+|Arsenate-reductase
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>CP022582.1|AXI05566.1|885632_885953_-|Thioredoxin
MQAIKSNESFKSIINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>CP022582.1|AXI05565.1|884942_885482_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>CP022582.1|AXI05564.1|884143_884860_+|3-dehydroquinate-dehydratase-I
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFINDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIIKHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>CP022582.1|AXI05563.1|883573_883996_-|Organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>CP022582.1|AXI05562.1|882680_883175_-|hypothetical-protein
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>CP022582.1|AXI05561.1|881908_882526_-|Transporter,-LysE-family
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQIISPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF
>CP022582.1|AXI05560.1|881254_881836_+|Phosphoglycerate-mutase-family
MAKTLYLMRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYYETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGIFEGESVYLFDNLYKPEDLFGDRIVPFKGEARQQVEERIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKLDEALKHNIGNCNILKFEYDNGTFKFVELIDPNL
>CP022582.1|AXI05570.1|888844_889231_+|Toprim-domain-protein
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>CP022582.1|AXI05571.1|889223_889520_+|Thioredoxin
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>CP022582.1|AXI05572.1|889769_890795_+|Methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVNMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEHGPVTQVFENPQHTVTKRFVKEDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>CP022582.1|AXI05573.1|890787_891483_+|Methionine-ABC-transporter-permease-protein
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWIVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>CP022582.1|AXI05574.1|891500_892322_+|Methionine-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYDLDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>CP022582.1|AXI05575.1|892675_892870_+|hypothetical-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>CP022582.1|AXI05576.1|893103_893955_-|membrane-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTGLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFTGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>CP022582.1|AXI05577.1|894282_895044_+|Iron-sulfur-cluster-assembly-ATPase-protein-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>CP022582.1|AXI05578.1|895141_896449_+|Iron-sulfur-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKHFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDKNASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>CP022582.1|AXI05579.1|896563_897805_+|SulS-subfamily-cysteine-desulfurase
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPMQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF

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Crispr_ID: CP022582_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022582_9

2158060-2158141

Orphan

Consensus_repeat	Method
GGCCCCCACCCCAACTTACATTGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022582_9

>merge|CP022582|9|2158060-2158141|CRISPRCasFinder
GGCCCCCACCCCAACTTACATTGTTTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCCACCCCAACTTGCATTGT

>CP022582|9|8|2158060-2158141|CRISPRCasFinder
GGCCCCCACCCCAACTTACATTGT	TTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGG
GGCCCCCACCCCAACTTGCATTGT

Protein	Signature genes	Signature genes Name	Protein_function
CP022582.1\|AXI06802.1\|2163084_2163645_+\|Secreted-protein-Ear,-superantigen-encoding-pathogenicity-islands-SaPI	unknown	unknown	gnl\|CDD\|294014
CP022582.1\|AXI06807.1\|2166870_2167089_-\|Hypothetical-protein	unknown	unknown	gnl\|CDD\|374753
CP022582.1\|AXI06804.1\|2165382_2165952_-\|Putative-terminase,-superantigen-encoding-pathogenicity-islands-SaPI	unknown	unknown	gnl\|CDD\|226251
CP022582.1\|AXI06790.1\|2146921_2147818_-\|ABC-type-multidrug-transport-system,-ATPase-component	unknown	unknown	gnl\|CDD\|224054
CP022582.1\|AXI06789.1\|2146240_2146921_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379133
CP022582.1\|AXI06798.1\|2156615_2157839_+\|Acetylornithine-deacetylase	unknown	unknown	gnl\|CDD\|181490
CP022582.1\|AXI06800.1\|2160606_2161329_+\|Superantigen-enterotoxin-SEL	unknown	unknown	gnl\|CDD\|280949
CP022582.1\|AXI06801.1\|2161497_2162298_-\|Superantigen-enterotoxin-SEB	unknown	unknown	gnl\|CDD\|280949
CP022582.1\|AXI06791.1\|2147814_2148195_-\|Transcriptional-regulator,-GntR-family	unknown	unknown	gnl\|CDD\|224639
CP022582.1\|AXI06808.1\|2167106_2167685_-\|Hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI06796.1\|2154086_2155103_-\|Leukocidin-LukF-PV	unknown	unknown	gnl\|CDD\|369625
CP022582.1\|AXI06799.1\|2158282_2159590_+\|Potassium-uptake-protein,-integral-membrane-component,-KtrB	unknown	unknown	gnl\|CDD\|273349
CP022582.1\|AXI06806.1\|2166292_2166820_-\|Spore-coat-protein	unknown	unknown	gnl\|CDD\|227864
CP022582.1\|AXI06793.1\|2149169_2150456_+\|Aspartate-aminotransferase	unknown	unknown	gnl\|CDD\|181512
CP022582.1\|AXI06803.1\|2164523_2165228_+\|Toxic-shock-syndrome-toxin-1-(TSST-1)	unknown	unknown	gnl\|CDD\|171853
CP022582.1\|AXI06794.1\|2150734_2152468_-\|Extracellular-adherence-protein-of-broad-specificity-Eap/Map	unknown	unknown	gnl\|CDD\|367591
CP022582.1\|AXI06795.1\|2152856_2153849_+\|Endonuclease/Exonuclease/phosphatase-family	unknown	unknown	gnl\|CDD\|132436
CP022582.1\|AXI06805.1\|2165948_2166290_-\|pathogenicity-island-protein	unknown	unknown	unknown
CP022582.1\|AXI06792.1\|2148452_2148629_-\|hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI06797.1\|2155124_2156180_-\|Leukocidin-LukS-PV	unknown	unknown	gnl\|CDD\|369625

Protein	Function_ID	Function_description	E-value
CP022582.1\|AXI06802.1\|2163084_2163645_+\|Secreted-protein-Ear,-superantigen-encoding-pathogenicity-islands-SaPI	gnl\|CDD\|294014	cd15783, SA1633_like, Uncharacterized protein family conserved in Staphylococci. Some proteins in this family have been described as putative beta-lactamases. They are structurally similar to the C-terminal beta-grasp domains of Staphylococcal and Streptococcal superantigens.	1.47157e-43
CP022582.1\|AXI06807.1\|2166870_2167089_-\|Hypothetical-protein	gnl\|CDD\|374753	pfam16722, SAPIS-gp6, Pathogenicity island protein gp6 in Staphylococcus. SAPIS-gp6 is a family of proteins produced from the pathogenicity island SAPI1 in pathogenic Staphylococcus aureus. This is a mobile genetic element that carries genes for several superantigen toxins. SAPIS-gp6 is a dimeric protein produced from the pathogenicity island with a helix-loop-helix motif similar to that of bacteriophage scaffolding proteins. It is thought to determine the size of the capsids of distribution of the SAPI1 genome as it acts as an internal scaffolding protein during capsid size determination.	1.38272e-18
CP022582.1\|AXI06804.1\|2165382_2165952_-\|Putative-terminase,-superantigen-encoding-pathogenicity-islands-SaPI	gnl\|CDD\|226251	COG3728, XtmA, Phage terminase, small subunit [DNA replication, recombination, and repair].	4.68659e-70
CP022582.1\|AXI06790.1\|2146921_2147818_-\|ABC-type-multidrug-transport-system,-ATPase-component	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	6.75378e-72
CP022582.1\|AXI06789.1\|2146240_2146921_-\|hypothetical-protein	gnl\|CDD\|379133	pfam13346, ABC2_membrane_5, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	1.92094e-11
CP022582.1\|AXI06798.1\|2156615_2157839_+\|Acetylornithine-deacetylase	gnl\|CDD\|181490	PRK08588, PRK08588, succinyl-diaminopimelate desuccinylase; Reviewed.	0
CP022582.1\|AXI06800.1\|2160606_2161329_+\|Superantigen-enterotoxin-SEL	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	6.68431e-31
CP022582.1\|AXI06801.1\|2161497_2162298_-\|Superantigen-enterotoxin-SEB	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	1.74895e-25
CP022582.1\|AXI06791.1\|2147814_2148195_-\|Transcriptional-regulator,-GntR-family	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	7.00479e-47
CP022582.1\|AXI06796.1\|2154086_2155103_-\|Leukocidin-LukF-PV	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	3.71545e-100
CP022582.1\|AXI06799.1\|2158282_2159590_+\|Potassium-uptake-protein,-integral-membrane-component,-KtrB	gnl\|CDD\|273349	TIGR00933, Trk_system_potassium_uptake_protein_trkH., potassium uptake protein, TrkH family. The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds].	1.35788e-81
CP022582.1\|AXI06806.1\|2166292_2166820_-\|Spore-coat-protein	gnl\|CDD\|227864	COG5577, COG5577, Spore coat protein [Cell envelope biogenesis, outer membrane].	5.42048e-39
CP022582.1\|AXI06793.1\|2149169_2150456_+\|Aspartate-aminotransferase	gnl\|CDD\|181512	PRK08637, PRK08637, hypothetical protein; Provisional.	0
CP022582.1\|AXI06803.1\|2164523_2165228_+\|Toxic-shock-syndrome-toxin-1-(TSST-1)	gnl\|CDD\|171853	PRK13038, PRK13038, superantigen-like protein; Reviewed.	1.96896e-09
CP022582.1\|AXI06794.1\|2150734_2152468_-\|Extracellular-adherence-protein-of-broad-specificity-Eap/Map	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	1.80099e-32
CP022582.1\|AXI06795.1\|2152856_2153849_+\|Endonuclease/Exonuclease/phosphatase-family	gnl\|CDD\|132436	TIGR03395, Sphingomyelinase_C, sphingomyelin phosphodiesterase. Members of this family are bacterial proteins that act as sphingomyelin phosphodiesterase (EC 3.1.4.12), also called sphingomyelinase. Some members of this family have been shown to act as hemolysins. [Cellular processes, Pathogenesis].	2.20388e-136
CP022582.1\|AXI06797.1\|2155124_2156180_-\|Leukocidin-LukS-PV	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	1.84035e-77

>CP022582.1|AXI06798.1|2156615_2157839_+|Acetylornithine-deacetylase
MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGNQDNWTYPPFQLTEKAGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGLIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGKEISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEASIQYLKEK
>CP022582.1|AXI06797.1|2155124_2156180_-|Leukocidin-LukS-PV
MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKDKRNVTNKDKNSTVPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKEG
>CP022582.1|AXI06796.1|2154086_2155103_-|Leukocidin-LukF-PV
MIKQLYKNITICSLAISTALTVFPATSYAKINSEIKAVSEKNLDGDTKMYTRTATTSDSQKIITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDFSINRGGLTGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDKGKSQFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHDVKFVKVLNDNEKK
>CP022582.1|AXI06795.1|2152856_2153849_+|Endonuclease/Exonuclease/phosphatase-family
MVKKTKSNSLKKVATLALANLLLVGALTDNSAKAESKKDDTDLKLVSHNVYMLSTVLYPNWGQYKRADLIGQSSYIKNNDVVIFNEAFDNGASDKLLSNVKKEYPYQTPVLGRSQSGWDKTEGSYSSTVAEDGGVAIVSKYPIKEKIQHVFKSGCGFDNDSNKGFVYTKIEKNGKNVHVIGTHTQSEDSRCGAGNDRKIRAEQMKEISDFVKKKNIPKDETVYIGGDLNVNKGTPEFKDMLKNLNVNDVLYAGHNSTWDPQSNSIAKYNYPNGKPEHLDYIFTDKDHKQPKQLVNEVVTEKPKPWDVYAFPYYYVYNDFSDHYPIKAYSK
>CP022582.1|AXI06794.1|2150734_2152468_-|Extracellular-adherence-protein-of-broad-specificity-Eap/Map
MKFKSLITTTLALGVIASTGANFNTNEASAAAKPLDKSSSTLHHGHSNIQIPYTITVNGTSQNILSSLTFNKNQNISYKDIENKVKSVLYFNRGISDIDLRLSKQAEYTVHFKNGTKRVIDLKSGIYTADLINTSDIKAISVNVDTKKQPKDKAKANVQVPYTITVNGTSQNILSNLTFNKNQNISYKDLEGKVKSVLESNRGITDVDLRLSKQAKYTVNFKNGTKKVIDLKSGIYTANLINSSDIKSININVDTKKHIENKAKRNYQVPYSINLNGTSTNILSNLSFSNKPWTNYKNLTSQIKSVLKHDRGISEQDLKYAKKAYYTVYFKNGGKRILQLNSKNYTANLVHAKDVKRIEITVKTGTKAKADRYVPYTIAVNGTSTPILSKLKISNKQLISYKYLNDKVKSVLKSERGISDLDLKFAKQAKYTVYFKNGKKQVVNLKSDIFTPNLFSAKDIKKIDIDVKQYTKSKKINKSNNVKFPVTINKFENIVSNEFVFYNASKITINDLSIKLKSAMANDQGITKHDIGLAERAVYKVYFKNGSSKYVDLKTEYKDERVFKATDIKKVDIELKF
>CP022582.1|AXI06793.1|2149169_2150456_+|Aspartate-aminotransferase
MNPLAQSLNEQLQQSNATAFTMLSDLGQNMFYPKGILSQSAEAKSTTYNATIGMATNKDGKMFASSLDAMFNDLTPDEIFPYAPPQGIEELRDLWQQKMLRDNPELSIDNMSLPIVTNALTHGLSLVGDLFVNQGDTILLPEHNWGNYKLVFNTRNGANLQTYPIFDKDGHYTTDSLVEALQSYNKDKVIMILNYPNNPTGYTPTHKEVTTIVDAIKALADKGTKVIAVVDDAYYGLFYEDVYTQSLFTALSNLNSNAILPVRLDGATKEFFAWGFRVGFMTFGTSDQTTKEVLEAKVKGLIRSNISSGPLPTQSAVKHVLKNNKQFDKEIEQNIQTLKERYEVTKEVVYADQYHSHWQAYDFNSGYFMAIKVHDVDPEELRKHLIEKYSIGVIALNATDIRIAFSCVEKEDIPHVFDSIAKAIDDLR
>CP022582.1|AXI06792.1|2148452_2148629_-|hypothetical-protein
MKHLTKIFVVLAIILFIIGYYLQATNHESQGIKLLLAAIMFMICAFISRSNDRRKNSK
>CP022582.1|AXI06791.1|2147814_2148195_-|Transcriptional-regulator,-GntR-family
MKIILKNNSDFPIYEQIKQQVKQNILKGHVAPGEHLPSMRELAKDLQVSLITTKRAYEDLEKDGFVTTIRGKGTFVKEQDSSILKEKQFFTIENLVKELVNEAQAIEMSLEELQDILTFIYEEESS
>CP022582.1|AXI06790.1|2146921_2147818_-|ABC-type-multidrug-transport-system,-ATPase-component
MNAIELSNVNYSSDQFNLKNISFKVPQGFVTGFIGRNGAGKTTIIRLIMDLYQPQTGVIRVLEEDMALNPIELKNSIGFVYSENYFNERWTTKQLEKMIAPFYRKWDHQVFEFYLEKFDLPINKSIKTFSTGMKMKLSLAVAFSHHAELYIFDEPTSGLDPLARNELLEIIQQELIDENKTIFMSTHIISDLEKIADYIIHLSDGEVILNGSKEQLLQRYQVVSGATEDLDDELASLLIYEEHKRTGFIGLTEHAQVFKEILGHKVNITTPSIENLMVYLEKRKPKYHENIKLMEEGF
>CP022582.1|AXI06789.1|2146240_2146921_-|hypothetical-protein
MKALLIRNFKLRRYTLIIYVLLLTLYPFYIMLDSTKFFYLLQSFISPTILIIWILDAGHLFRLNRRLGGNDSYYFYMSLPVSKKQLLNANYITCIVLTLIGTLVISLYAYEADVIEPNSIYFSTAYAFVISNFLSIPIAFSQFTELRRVKVPYGIYVFTIIILVPFLFSIAIVLVNYFVLSQSSFPDLYSYILNIGFLIISIVILIVNYFKQLNKINTRKFKGGSR
>CP022582.1|AXI06799.1|2158282_2159590_+|Potassium-uptake-protein,-integral-membrane-component,-KtrB
MNKVHKPLYFYLMLFFSTTIIGALLLYLPFTGKKPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKISMKNRFLIMVTWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSFIPKFGIGKGLFLSLFTSVSAFNNAGFALFKNNLIDYSSDPIVIITISILIIFGGIGHFVVIDFINCKKMSKLSLHSKLVLTTTSILIIIGAITFFLLEQFNTMQHMGLVEKIGNSFFQSVTTRTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRKENNVSVFNKEISDKHIKLSIVTINISFLFISIITFILSIINPNISLIKLLFEVVSAFGTVGLSMNLTTEYHGITKIIIIFVMLCGKVGLLTLLRTFIPPKSPKNYRYTKGQIYL
>CP022582.1|AXI06800.1|2160606_2161329_+|Superantigen-enterotoxin-SEL
MKKRLLFVIVITLFIFSSNHTVLSNGDVGPGNLRNFYTKYEYVNLKNVKDKNSPESHRLEYSYKNDTLYAEFDNEYITSDLKGKNVDVFGISYKYGSNSRTIYGGVTKAENNKLDSPRIIPINLIINGKHQTVTTKSVSTDKKMVTAQEIDVKLRKYLQDEFNIYGHNDTGKGKEYGTSSKFYSGFDKGSVVFHMNDGSNFSYDLFYTGYGLPESFLKIYKDNKTVDSTQFHLDVEISKR
>CP022582.1|AXI06801.1|2161497_2162298_-|Superantigen-enterotoxin-SEB
MYKRLFISRVILIFALILVISTPNVLAESQPDPMPDDLHKSSEFTGTMGNMKYLYDDHYVSATKVKSVDKFLAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYKDEVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEVQTDKKSVTAQELDIKARNFLINKKNLYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDNKTVDSKSVKIEVHLTTKNG
>CP022582.1|AXI06802.1|2163084_2163645_+|Secreted-protein-Ear,-superantigen-encoding-pathogenicity-islands-SaPI
MNKKLLTKTLIASALVLTTVGSGFHSSSNYNGINNVAKAEQTTDNALWKNVRDALKDANIIDKTDNENVKVTYKIENGGENTIEGTANLENISTSNNPKINPQNVTKINITRKNSNYPNIDANNTWKKLTEKLKEKNIVNNGDNVSILSTDPKDETVFGKVGEDKSNVSNRYINPKDINEIQITKK
>CP022582.1|AXI06803.1|2164523_2165228_+|Toxic-shock-syndrome-toxin-1-(TSST-1)
MNKKLLMNFFIVSPLLLATIATDFTPVPLSSNQIIKTAKASTNDNIKDLLDWYSSGSDTFTNSEVLDNSLGSMRIKNTDGSISLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELPLKVKVHGKDSPLKYWPKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEIN
>CP022582.1|AXI06804.1|2165382_2165952_-|Putative-terminase,-superantigen-encoding-pathogenicity-islands-SaPI
MSELTAKQARFVNEYIRTLNVTQSAIKAGYSANSAHVTGCRLLKKPHIKQYIQEQKDKVIDENVLTAKELLHVLTNAAVGDETETKEVVVKRGEYKENPQSGKVQLVYNEHVELVEVPIKPSDRLKARDMLGKYHKLFTDKHDINGNVPIFINIGEWDGDDEDLDKTVQEVSNANPNHTVIVDDIPLED
>CP022582.1|AXI06805.1|2165948_2166290_-|pathogenicity-island-protein
MDKKQIKDFVCDYHKRTISDVLIDDEINTDEFFSIGDENSNEWMADDNIDDHIVKNHLEMIVDQVANDKEFYIFDSLIQGRSFKDISNVLECSEQSVRLWYETLLDKIVEVIE
>CP022582.1|AXI06806.1|2166292_2166820_-|Spore-coat-protein
MKLLKTKNCLYYRNGDNKLSEYQLLTQFNPAFINKKIKMCEFQIESMYHMSASTTTCDEIMGVVSVSYPIEKLVIKIIETKAGLQNYKNRSINNMALLKKVLNHYTEKEQKQVVKYMRSNGRYKPYNVIERLQVDLYQASIKQRSERQKQRNTAIENSKIARVNAYHQSSYVKVV
>CP022582.1|AXI06807.1|2166870_2167089_-|Hypothetical-protein
METKYELNNTKKVANAFGLNEADTNLLINAVDLDIKNNMQEISSELQQSEQSKQKQYGTTLQNLAKQNRIIK
>CP022582.1|AXI06808.1|2167106_2167685_-|Hypothetical-protein
MKTESYFKEYNQFVIDQQKAIQELEQERNALESKIKIDKSTYKQLIMDGQDDKADNLYQATDADEKKLKALNKRLETKKSVSKEVKYQKTIELLKHQSELSSLYESEKQSALGKLKKVVDAYNEIIDEIEDINDRYEDEHQQYASIYSQEQLYDDKEAREALNGYFRENIFTSYINGNDLPYEHNNKLFLKR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP022582_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022582_10

2173705-2173793

Orphan

Consensus_repeat	Method
GTTTTTGACTGACTTCTCAATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022582_10

>merge|CP022582|10|2173705-2173793|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCAATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAGTTTTTCGACTGACTTCTCAATCA

>CP022582|10|9|2173705-2173793|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCA	ATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAG
TTTTTCGACTGACTTCTCAATCA

Protein	Signature genes	Signature genes Name	Protein_function
CP022582.1\|AXI06828.1\|2183630_2184914_+\|GHKL-domain	unknown	unknown	gnl\|CDD\|225519
CP022582.1\|AXI06822.1\|2177480_2177594_-\|Heat-shock-protein-60-family-co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
CP022582.1\|AXI06826.1\|2181208_2181922_+\|Aliphatic-amidase-AmiE	unknown	unknown	gnl\|CDD\|143607
CP022582.1\|AXI06809.1\|2167696_2168038_-\|pathogenicity-island-protein	unknown	unknown	unknown
CP022582.1\|AXI06818.1\|2173468_2173687_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
CP022582.1\|AXI06812.1\|2169815_2171525_-\|Putative-DNA-helicase,-superantigen-encoding-pathogenicity-islands-SaPI	unknown	unknown	gnl\|CDD\|227806
CP022582.1\|AXI06813.1\|2171538_2172408_-\|mobile-element-associated-protein	unknown	unknown	gnl\|CDD\|214926
CP022582.1\|AXI06811.1\|2169125_2169506_-\|pathogenicity-island-protein	unknown	unknown	unknown
CP022582.1\|AXI06825.1\|2180150_2180777_+\|Nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
CP022582.1\|AXI06810.1\|2168487_2169129_-\|pathogenicity-island-protein	unknown	unknown	gnl\|CDD\|374630
CP022582.1\|AXI06824.1\|2178706_2179954_-\|Membrane-anchored-protein	unknown	unknown	gnl\|CDD\|236768
CP022582.1\|AXI06827.1\|2182891_2183455_+\|Accessory-gene-regulator-B,-AgrB	unknown	unknown	gnl\|CDD\|226899
CP022582.1\|AXI06815.1\|2172801_2173011_-\|Hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI06819.1\|2173859_2174534_+\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
CP022582.1\|AXI06816.1\|2173003_2173150_-\|Hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI06820.1\|2174547_2175720_+\|Integrase,-superantigen-encoding-pathogenicity-islands-SaPI	unknown	unknown	gnl\|CDD\|271189
CP022582.1\|AXI06821.1\|2175788_2177405_-\|Heat-shock-protein-60-family-chaperone-GroEL	unknown	unknown	gnl\|CDD\|234573
CP022582.1\|AXI06817.1\|2173146_2173464_-\|excisionase	unknown	unknown	gnl\|CDD\|200128
CP022582.1\|AXI06823.1\|2177938_2178682_+\|CAAX-amino-terminal-protease-family-protein	unknown	unknown	gnl\|CDD\|376806
CP022582.1\|AXI06814.1\|2172472_2172799_-\|DUF1474-domain-containing-protein	unknown	unknown	gnl\|CDD\|369323

Protein	Function_ID	Function_description	E-value
CP022582.1\|AXI06828.1\|2183630_2184914_+\|GHKL-domain	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.49577e-44
CP022582.1\|AXI06822.1\|2177480_2177594_-\|Heat-shock-protein-60-family-co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	8.28588e-15
CP022582.1\|AXI06812.1\|2169815_2171525_-\|Putative-DNA-helicase,-superantigen-encoding-pathogenicity-islands-SaPI	gnl\|CDD\|227806	COG5519, COG5519, Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair].	0
CP022582.1\|AXI06818.1\|2173468_2173687_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	9.85461e-11
CP022582.1\|AXI06813.1\|2171538_2172408_-\|mobile-element-associated-protein	gnl\|CDD\|214926	smart00942, PriCT_1, Primase C terminal 1 (PriCT-1). This alpha helical domain is found at the C terminal of primases.	1.21323e-15
CP022582.1\|AXI06820.1\|2174547_2175720_+\|Integrase,-superantigen-encoding-pathogenicity-islands-SaPI	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.67501e-47
CP022582.1\|AXI06825.1\|2180150_2180777_+\|Nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	8.42197e-117
CP022582.1\|AXI06810.1\|2168487_2169129_-\|pathogenicity-island-protein	gnl\|CDD\|374630	pfam16560, SAPI, Putative mobile pathogenicity island. SAPI is a family of putative Gram-positive mobile pathogenicity island proteins. SAPIs are responsible for many superantigen-related diseases in humans as they carry two or more superantigens.	3.70035e-117
CP022582.1\|AXI06824.1\|2178706_2179954_-\|Membrane-anchored-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	8.13501e-10
CP022582.1\|AXI06827.1\|2182891_2183455_+\|Accessory-gene-regulator-B,-AgrB	gnl\|CDD\|226899	COG4512, AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide [Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription].	6.65966e-71
CP022582.1\|AXI06819.1\|2173859_2174534_+\|XRE-family-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.58614e-10
CP022582.1\|AXI06826.1\|2181208_2181922_+\|Aliphatic-amidase-AmiE	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	1.43659e-116
CP022582.1\|AXI06821.1\|2175788_2177405_-\|Heat-shock-protein-60-family-chaperone-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
CP022582.1\|AXI06817.1\|2173146_2173464_-\|excisionase	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	5.89089e-17
CP022582.1\|AXI06823.1\|2177938_2178682_+\|CAAX-amino-terminal-protease-family-protein	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.67124e-11
CP022582.1\|AXI06814.1\|2172472_2172799_-\|DUF1474-domain-containing-protein	gnl\|CDD\|369323	pfam07342, DUF1474, Protein of unknown function (DUF1474). This family consists of several bacterial proteins of around 100 residues in length. Members of this family seem to be found exclusively in Staphylococcus aureus. The function of this family is unknown.	1.179e-19

>CP022582.1|AXI06818.1|2173468_2173687_-|XRE-family-transcriptional-regulator
MTILANTRKFKEAMFLKGFNLSDLSRETGVGISYLSQIINGKKIPSPKLAKKMAEVLQVEVNELFEFEVKEA
>CP022582.1|AXI06817.1|2173146_2173464_-|excisionase
MFNINIDEDEARELLEQAINARVDELAKEKYFMTYKELSNYLNLSKPTIEELLINNGMKYYMVGSTYRFKKSDVDEFMEQLTAHMNIQNNDFKQVNIKKLLEARQ
>CP022582.1|AXI06816.1|2173003_2173150_-|Hypothetical-protein
MKMYLTYICLVSLLTILLLAISNMYVAFSVYAWLITLGCNLTGGLENE
>CP022582.1|AXI06815.1|2172801_2173011_-|Hypothetical-protein
MNNEQKEVIEHVVYQLELSVVNNLESYEHTEYVNGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE
>CP022582.1|AXI06814.1|2172472_2172799_-|DUF1474-domain-containing-protein
MNREIKDLFSDLKLLKDSFEDLKDSNGWHFDELYPYEPNHVLNKDELIGEGFSYHERRIHNNQMFDLFHLYIEQFDNIIEKFYEIEKASSENFGEESDDAKNSIKVAE
>CP022582.1|AXI06813.1|2171538_2172408_-|mobile-element-associated-protein
MNEIKLEYDTHVSVVHYESLDSRSFKSFSKPEWSKLVNKLSVPIEANYKYARGVAVYGDIKDGANDHGETIKKHRNDVNVIYRDVIVLDYDEINDLKQLHEAISSVLSSVAWYWHTSFSHTTEQARIRLYIPLNERISADDYRKYTKVLANKIGHKVDEGSYQPSRCFALPVIQKGHIFIKRVNDCPIMNVDMLEQWSKEFEQSNASPNVIGYTRRDSEYWRELCFGTTEGNRNNALASLIGHLLRCHVNDYIVYSFALLWGQFACKPPMKEQEINATFQSILNKHYNN
>CP022582.1|AXI06812.1|2169815_2171525_-|Putative-DNA-helicase,-superantigen-encoding-pathogenicity-islands-SaPI
METGKSDVLDKIEKINKKDSALQEIIPKGYEIEHHQCGVALYQLIPSKKEGEPDKKVFITNTIPQITERFEDIESNEVSFNMLFYDNKTPVNIAVSAEEISDSRQLLKLVNKKLDVTSSTSTKLVDYINVSKRYNPPLNVKVATRLGHVKGYFIYPYQEVMKDSNVKLFSNDKGFQKLIDSFRSKGTLQGYSKKVFAQIKDLPMVMVMLYASLGSVLLREFGLQPFIVEISGSTSTGKTFTLNLVSSVWGTSDLITTWSSTQNSIESMASFLNSFPMFKDDTRNTHPKFVTSTTYNFSSGESKSRSNINLTLNAKKEWRNILISTGESSIANMADEKAGVSARVVTLQDPPYPDNFDFTTLDKSFRENYGTLGLAFIKQYESKKDVYKNAFESYQRYFNQKGSNEIMQRLGRAFALLQVTGEVLNDIDGFEHDHFKIIEQAYDSMVKNNKTIDKPKQLLEELLQYLDANRNNIVGDGYDSVNYGDVKAVYKHDFLCIKNETVKNKLGHEMQTITGQWDKKGYLIKDKKRIQKQVKHKSQRHLGYAIKKEIIEELGFDFSISHNPYTESY
>CP022582.1|AXI06811.1|2169125_2169506_-|pathogenicity-island-protein
MDKEQLKKYIYEYVKEYKEIPIYQLEDLFKEINHDYIGRTSITHDKDENIVFWSGWNKITMFALIELVKSEQLDLVYRGSFIMRYLLDGRVPNLPLAICYPEDGQQTDVPSWVPMVLRINKEEKIK
>CP022582.1|AXI06810.1|2168487_2169129_-|pathogenicity-island-protein
MNLETIVNQFETRAGTLLRYYTGLLEHSKVQPCCFKLYNDPFDMVYVMMNSKLFGHVYIKDCKVRQSFELASPKHTEGLIRSIEGHYVGYELHDGKHLSISDMMASHLFEDEYFMYGLQTYAESNNSDVFEYLENGFDTDTLEGIQSSNTDVIANIEMLYQLATGINEPAPELVEGLKLVTEFVQDENATQEDYKALERKLNDLKASYYSLSK
>CP022582.1|AXI06809.1|2167696_2168038_-|pathogenicity-island-protein
MQSIAEKETYHLPTEHLQVFNVIKNTSNKYITKTKILNQLGYEYNSSNERWLRRVINSLVYDYGYPIGCSYKPSERGYYIITTEQEKQQAMRSIKKLADGSMKRYEALKRIKV
>CP022582.1|AXI06819.1|2173859_2174534_+|XRE-family-transcriptional-regulator
MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRYDAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIENFDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSLSAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKSTTLHKEILQTDSRLSSDIFKEY
>CP022582.1|AXI06820.1|2174547_2175720_+|Integrase,-superantigen-encoding-pathogenicity-islands-SaPI
MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHAEMVERQLRNGDYIAPSTSTFKQVADDWISQYANEVKVSSVRAREKAIHHAIERFKNKPIQTIKKHDYQRFVNDISIQYSKNYVDSIVTSTNMIFKYAYDMKLIRILPSEGIKRPKKKVSVEELEDTEIHKKFLEKDELFQFLEIAKNHHSPQNSFEVFYTLAYTGMRAGELLALKWSDIDFENNTINITKTYYNPNNNKKQYQILTPKTESSIGKISVDPHVIKLLKNYKVDVQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTNITNKQISTHSFRHTHCALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSKLMENVSKDLF
>CP022582.1|AXI06821.1|2175788_2177405_-|Heat-shock-protein-60-family-chaperone-GroEL
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>CP022582.1|AXI06822.1|2177480_2177594_-|Heat-shock-protein-60-family-co-chaperone-GroES
MKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>CP022582.1|AXI06823.1|2177938_2178682_+|CAAX-amino-terminal-protease-family-protein
MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVVSIVLTQIYGGQQVSPNTEKLIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGNRIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>CP022582.1|AXI06824.1|2178706_2179954_-|Membrane-anchored-protein
MSYHWFKKMLLSTSILILSSSSLGLATHTVEAKDNLNGEKPTTNLNHNITSPSVNSEMNNNETGTPHESNQTGNEGTGSNSRDANPDSNNVKPDSNNQNPSTDSKPDPNNQNPSPNPKPDPDNPKPKPDPDKPKPNLDPKPDPDNPKPKPDPKPDPDKPKPNPDPKPDPDKPKPNPNPKPDPNKPNPNPSPDPDQPGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>CP022582.1|AXI06825.1|2180150_2180777_+|Nitroreductase-family-protein
MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSKEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK
>CP022582.1|AXI06826.1|2181208_2181922_+|Aliphatic-amidase-AmiE
MVRKNMNAEVDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNYQIFNTAFSVNKSGQLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESADILTVDLNLNEVEQQRENIPVFKSIKLDLYK
>CP022582.1|AXI06827.1|2182891_2183455_+|Accessory-gene-regulator-B,-AgrB
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFFKILVTYSISIFLSVFLFTLVTHLSYMLIRYNAHGAHAKSSILCYIQSILTFVFVPYFLINIDINFTYLLALSIIGLISVVIYAPAATKKQPIPIKLVKRKKYLSIIMYLLVLILSLIIHPFYAQFMLLGILVESITLLPIFFPKED
>CP022582.1|AXI06828.1|2183630_2184914_+|GHKL-domain
METINNLAMATFQLVILFTVAKFISFVKFNLRDYFIIVGIIIPTMFLYYFYGSRAVLIPTFSSIIFLFFKLKYYAIVTILVTMIIMYLSNFATVGLFLTLRKYTTDPAILLPLYILSFSSVSLLATYLVRISLKKFKKSYLSLNKTYMIIISFVLFATFAFFYIYSTNTSSNGDSLIPYALVFIGLIIFISVVILIMSLFTLKEMKYKRNQEEIETYYEYTLKIEAINNEMRKFRHDYVNILTTLSEYIREDDMIGLRAYFNKNIVPMKDNLQMNAIKLNGIENLKVREIKGLITAKILRAQEMNIPISIEIPDEVSSINLNMIDLSRSIGIILDNAIEASTEIDDPIIRVAFIESENSVTFIVMNKCADDIPRIHELFQESFSTKGEGRGLGLSTLKEIADNADNVLLDTIIENGFFIQKVEIINN

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Crispr_ID: CP022582_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022582_11

2302661-2302741

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of CP022582_11

>merge|CP022582|11|2302661-2302741|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTCAACTTTAGTTGTTAGGGGCTTCT

>CP022582|11|10|2302661-2302741|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTT	ATGCATGCGCTTAGCGCAGGCGCTCCTACTTTT
CAACTTTAGTTGTTAGGGGCTTCT

Protein	Signature genes	Signature genes Name	Protein_function
CP022582.1\|AXI06929.1\|2294621_2295035_-\|DUF393-domain-containing-protein	unknown	unknown	gnl\|CDD\|225556
CP022582.1\|AXI06933.1\|2299171_2299837_-\|oxidoreductase-ylbE	unknown	unknown	gnl\|CDD\|187554
CP022582.1\|AXI06935.1\|2300310_2301288_+\|Cobalt-zinc-cadmium-resistance-protein-CzcD	unknown	unknown	gnl\|CDD\|224151
CP022582.1\|AXI06934.1\|2299988_2300309_+\|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
CP022582.1\|AXI06939.1\|2304676_2305534_-\|HMP-PP-hydrolase-(pyridoxal-phosphatase)-Cof	unknown	unknown	gnl\|CDD\|223635
CP022582.1\|AXI06942.1\|2309101_2310640_+\|PTS-system,-mannitol-specific-IIBC-component	unknown	unknown	gnl\|CDD\|225123
CP022582.1\|AXI06944.1\|2312818_2313253_+\|PTS-system,-mannitol-specific-IIA-component	unknown	unknown	gnl\|CDD\|227014
CP022582.1\|AXI06937.1\|2303697_2303868_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226950
CP022582.1\|AXI06931.1\|2297536_2297767_-\|putative-membrane-protein	unknown	unknown	unknown
CP022582.1\|AXI06928.1\|2293978_2294422_-\|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase	unknown	unknown	gnl\|CDD\|223854
CP022582.1\|AXI06930.1\|2295491_2296865_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
CP022582.1\|AXI06940.1\|2305601_2306384_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
CP022582.1\|AXI06938.1\|2303860_2304019_+\|hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI06932.1\|2297797_2298736_-\|Mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
CP022582.1\|AXI06943.1\|2310674_2312807_+\|Mannitol-operon-activator,-BglG-family	unknown	unknown	gnl\|CDD\|226234
CP022582.1\|AXI06945.1\|2313252_2314359_+\|Mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
CP022582.1\|AXI06941.1\|2306615_2308421_-\|Glucosamine--fructose-6-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|234729
CP022582.1\|AXI06946.1\|2314677_2322123_-\|FmtB-(Mrp)-protein-involved-in-methicillin-resistance-and-cell-wall-biosynthesis	unknown	unknown	gnl\|CDD\|275089
CP022582.1\|AXI06936.1\|2301553_2302471_+\|Lytic-regulatory-protein	unknown	unknown	unknown
CP022582.1\|AXI06927.1\|2293147_2293858_+\|Purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275

Protein	Function_ID	Function_description	E-value
CP022582.1\|AXI06929.1\|2294621_2295035_-\|DUF393-domain-containing-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
CP022582.1\|AXI06933.1\|2299171_2299837_-\|oxidoreductase-ylbE	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.27122e-47
CP022582.1\|AXI06935.1\|2300310_2301288_+\|Cobalt-zinc-cadmium-resistance-protein-CzcD	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.49165e-107
CP022582.1\|AXI06934.1\|2299988_2300309_+\|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
CP022582.1\|AXI06939.1\|2304676_2305534_-\|HMP-PP-hydrolase-(pyridoxal-phosphatase)-Cof	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	6.8047e-59
CP022582.1\|AXI06942.1\|2309101_2310640_+\|PTS-system,-mannitol-specific-IIBC-component	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
CP022582.1\|AXI06944.1\|2312818_2313253_+\|PTS-system,-mannitol-specific-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
CP022582.1\|AXI06937.1\|2303697_2303868_+\|hypothetical-protein	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.00028059
CP022582.1\|AXI06943.1\|2310674_2312807_+\|Mannitol-operon-activator,-BglG-family	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.02509e-68
CP022582.1\|AXI06928.1\|2293978_2294422_-\|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
CP022582.1\|AXI06930.1\|2295491_2296865_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	4.11455e-06
CP022582.1\|AXI06940.1\|2305601_2306384_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.29094e-106
CP022582.1\|AXI06941.1\|2306615_2308421_-\|Glucosamine--fructose-6-phosphate-aminotransferase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP022582.1\|AXI06932.1\|2297797_2298736_-\|Mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	1.00589e-128
CP022582.1\|AXI06945.1\|2313252_2314359_+\|Mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
CP022582.1\|AXI06946.1\|2314677_2322123_-\|FmtB-(Mrp)-protein-involved-in-methicillin-resistance-and-cell-wall-biosynthesis	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	1.54008e-108
CP022582.1\|AXI06927.1\|2293147_2293858_+\|Purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157

>CP022582.1|AXI06936.1|2301553_2302471_+|Lytic-regulatory-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKLLKIK
>CP022582.1|AXI06935.1|2300310_2301288_+|Cobalt-zinc-cadmium-resistance-protein-CzcD
MSHSHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>CP022582.1|AXI06934.1|2299988_2300309_+|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>CP022582.1|AXI06933.1|2299171_2299837_-|oxidoreductase-ylbE
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>CP022582.1|AXI06932.1|2297797_2298736_-|Mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSKDLDSVFEGDFTLMISYV
>CP022582.1|AXI06931.1|2297536_2297767_-|putative-membrane-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>CP022582.1|AXI06930.1|2295491_2296865_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVKKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>CP022582.1|AXI06929.1|2294621_2295035_-|DUF393-domain-containing-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>CP022582.1|AXI06928.1|2293978_2294422_-|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>CP022582.1|AXI06927.1|2293147_2293858_+|Purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>CP022582.1|AXI06937.1|2303697_2303868_+|hypothetical-protein
MSPKDTTRFETKPDHQAQFDWKESINFKTKDNQRIPLYIGVLLLYYSRFIIMHNNE
>CP022582.1|AXI06938.1|2303860_2304019_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>CP022582.1|AXI06939.1|2304676_2305534_-|HMP-PP-hydrolase-(pyridoxal-phosphatase)-Cof
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>CP022582.1|AXI06940.1|2305601_2306384_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>CP022582.1|AXI06941.1|2306615_2308421_-|Glucosamine--fructose-6-phosphate-aminotransferase
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>CP022582.1|AXI06942.1|2309101_2310640_+|PTS-system,-mannitol-specific-IIBC-component
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>CP022582.1|AXI06943.1|2310674_2312807_+|Mannitol-operon-activator,-BglG-family
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>CP022582.1|AXI06944.1|2312818_2313253_+|PTS-system,-mannitol-specific-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>CP022582.1|AXI06945.1|2313252_2314359_+|Mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>CP022582.1|AXI06946.1|2314677_2322123_-|FmtB-(Mrp)-protein-involved-in-methicillin-resistance-and-cell-wall-biosynthesis
MNLFRQQKFSIRKFNVGIFSALIATVTFISTNPTTASAAEQNQPAQNQPAQPADANTQPNANAGAQANPAAQPANQGGQANPAGGAAQPAGQGNQADPNNAAQAQPGNQAAPANQAGQGNNQATPNNNATPANQTQPANAPAAAQPAAPVAANAQTQDPNASNTGEGSINTTLTFDDPAISTDENRQDPTVTVTDKVNGYSLINNGKIGFVNSELRRSDMFDKNNPQNYQAKGNVAALGRVNANDSTDHGNFNGITKTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLDLQFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGASLKADQFKYEVTLPQGVTYVNDSLTTTFPNGNEDSTVLKNMTVNYDQTANKVTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNVANIDTPKNIDFNEKLTYRTASDVVINNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAEYNKLKQQADTILNEDANHVETANRASQADIDGLVTKLQAALIDNQAAIAELDTKAQEKVTAAQQSKKVTQDEVAALVTKINNDKNNAIAEINKQTTSQGVTTEKDNGIAVLEQDVITPTVKPQAKQDIIQAVTTRKQQIKKSNASLQDEKDVANDKIGKIETKAIKDIDAATTNAQVEAIKTKAINDINQTTPATTAKAAALEEFDEVVQAQIDQAPLNPDTTNEEVAEAIERINAAKVSGVKAIEATTTAQDLERVKNEEIFKIENITDSTQTKMDAYKEVRQAATARKAQNATVSNATDEEVAEANAAVDAAQTEGLHDIQVVKSQQEVADTKAKVLDKINAIQTQAKVKPAADTEVENAYNTRKQEIQNSNASTTEEKEAAYTELDAKKQEARTNLDAANTNSDVTTAKDNGIAAINQVQAATTKKSDAKAEIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQAVVTANADIDNATANTDVDNAKTTNEATIAAITPDANVKPAAKQAIADKVQAQETAIDANNGSTTEEKEAAKQQVQTEKTAADAAIDAAHSNVEVEAAKNAEIAKIEAIQPATTTKDNAKQAIATKANERKTAIAQTQDITAEEIAAANADVDNAVTQANSNIEAANSQNDVDQAKTTGETSIDQVTPTVNKKATARNEITAILNNKLQEIQATPDATDEEKQAADAEANTENGKANQAISAATTNAQVDEAKANAEAAINAVTPKVVKKQAAKDEIDQLQATQTNVINNDQNATNEEKEAAIQQLATAVTDAKNNITAATDDNGVDTAKDAGKNSIQSTQPATAVKSNAKNEVDQAVTTQNQAIDNTTGATTEEKNAAKDLVLKAKEKAYQDILNAQTTNDVTQIKDQAVADIQGITADTTIKDVAKDELATKANEQKALIAQTADATTEEKEQANQQVDAQLTQGNQNIENAQSIDDVNTAKDNAIQAIDPIQASTDVKTNARAELLTEMQNKITEILNNNETTNEEKGNDIGPVRAAYEEGLNNINAATTTGDVTTAKDTAVQKVQQLHANPVKKPAGKKELDQAAADKKTQIEQTPNASQQEINDAKQEVDTELNQAKTNVDQSSTNEYVDNAVKEGKAKINAVKTFSEYKKDALAKIEDAYNAKVNEADNSNASTSSEIAEAKQKLAELKQTADQNVNQATSKDDIEVQIHNDLDNINDYTIPTGKKESATTDLYAYADQKKNNISADTNATQDEKQQAIKQVDQNVQTALENINNGVDNGDVDDALTQGKAAIDTIQVDATVKPKANQAIEAKAEDTKESIDHSDQLTAEEKTEALAMIKQITDQAKQGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVDADATTEEKEAFTNALEDILSKATEDISDQTTNAEIATVKNSALEQLKAQRINPVVKKNALEAIREVVNKQIEIIKNADADASAKEIARTDLGRYFDRFADKLDKTQTNTEVAELQNVTIPAIEAIVPQNDPDANDTNNGTDNNDATANSNANATPENTGQPNVSETTDNGKADASPTTPNNSDAATGETTVTSATDDAKDKPQANNNSSADASTNSPTMDNDVTSKPEVESTNNGTTDKPVTETDNATPAESTTNNNSTTTATNENAPTGSTATAPTTASTEAASSADSKDNASVNDSKQNAEVNNSAESQSTNGKVAQPKSENKAKAEKDGRDSTNQSMVESTTETLPSADITEPNVPSNTSKDKEESTTNQTDAGQLKSETNVASNEADKSPSKADTEVSNKPSTSASSEAKDKMTSTNVSQKDDTATADTNDTQKSVGPVANNKAKDMQTNDTQKSVGSAANNKATQNDGANASPATVSNGSHSMHQDMLNVTKPEENKANAKSDQQGKVNKPKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKDQQTEE

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Crispr_ID: CP022582_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022582_13

2422957-2423037

Orphan

Consensus_repeat	Method
TCTATGTTGGGGCCCCGCCAACTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022582_13

>merge|CP022582|13|2422957-2423037|CRISPRCasFinder
TCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTCTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTG

>CP022582|13|12|2422957-2423037|CRISPRCasFinder
TCTATGTTGGGGCCCCGCCAACTTG	CACATTATTGTAAGCTGACTTTCTGTCAGCT
TCTGTGTTGGGGCCCCGCCAACTTG

Protein	Signature genes	Signature genes Name	Protein_function
CP022582.1\|AXI07057.1\|2428364_2429369_-\|Molybdopterin-biosynthesis-protein-MoeB	unknown	unknown	gnl\|CDD\|181084
CP022582.1\|AXI07050.1\|2424222_2424822_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-MobA	unknown	unknown	gnl\|CDD\|234725
CP022582.1\|AXI07044.1\|2417684_2418950_-\|tRNA-dependent-lipid-II--glycine-ligase-(FmhB)	unknown	unknown	gnl\|CDD\|225224
CP022582.1\|AXI07058.1\|2429538_2430144_-\|Molybdenum-transport-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|226628
CP022582.1\|AXI07054.1\|2426009_2427269_-\|Molybdopterin-biosynthesis-protein-MoeA	unknown	unknown	gnl\|CDD\|238452
CP022582.1\|AXI07052.1\|2425067_2425514_-\|Molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
CP022582.1\|AXI07055.1\|2427331_2427826_+\|Molybdenum-cofactor-biosynthesis-protein-MoaC	unknown	unknown	gnl\|CDD\|236483
CP022582.1\|AXI07047.1\|2421030_2422152_+\|Major-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|341042
CP022582.1\|AXI07042.1\|2413899_2414217_+\|Hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI07039.1\|2410931_2411795_+\|glucose-uptake-protein	unknown	unknown	gnl\|CDD\|227309
CP022582.1\|AXI07051.1\|2424828_2425062_-\|Molybdenum-cofactor-biosynthesis-protein-MoaD	unknown	unknown	gnl\|CDD\|340452
CP022582.1\|AXI07041.1\|2413490_2413655_+\|Hypothetical-protein	unknown	unknown	unknown
CP022582.1\|AXI07056.1\|2427827_2428334_-\|Molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
CP022582.1\|AXI07053.1\|2425527_2426013_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-MobB	unknown	unknown	gnl\|CDD\|224677
CP022582.1\|AXI07049.1\|2423180_2424203_-\|Molybdenum-cofactor-biosynthesis-protein-MoaA	unknown	unknown	gnl\|CDD\|274250
CP022582.1\|AXI07043.1\|2414400_2417568_-\|RND-multidrug-efflux-transporter,-Acriflavin-resistance-protein	unknown	unknown	gnl\|CDD\|223911
CP022582.1\|AXI07048.1\|2422253_2422604_-\|Transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
CP022582.1\|AXI07040.1\|2412449_2413358_-\|Transporter	unknown	unknown	gnl\|CDD\|223751
CP022582.1\|AXI07045.1\|2419581_2420346_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
CP022582.1\|AXI07046.1\|2420507_2420948_+\|Transcriptional-regulator,-MarR-family	unknown	unknown	gnl\|CDD\|197670

Protein	Function_ID	Function_description	E-value
CP022582.1\|AXI07057.1\|2428364_2429369_-\|Molybdopterin-biosynthesis-protein-MoeB	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	6.83722e-133
CP022582.1\|AXI07050.1\|2424222_2424822_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	2.15389e-66
CP022582.1\|AXI07055.1\|2427331_2427826_+\|Molybdenum-cofactor-biosynthesis-protein-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	2.93711e-97
CP022582.1\|AXI07058.1\|2429538_2430144_-\|Molybdenum-transport-ATP-binding-protein-ModC	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	1.78595e-116
CP022582.1\|AXI07054.1\|2426009_2427269_-\|Molybdopterin-biosynthesis-protein-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	4.50966e-159
CP022582.1\|AXI07052.1\|2425067_2425514_-\|Molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	6.99133e-58
CP022582.1\|AXI07056.1\|2427827_2428334_-\|Molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	2.42221e-64
CP022582.1\|AXI07047.1\|2421030_2422152_+\|Major-facilitator-family-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.02034e-68
CP022582.1\|AXI07044.1\|2417684_2418950_-\|tRNA-dependent-lipid-II--glycine-ligase-(FmhB)	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	1.81413e-143
CP022582.1\|AXI07039.1\|2410931_2411795_+\|glucose-uptake-protein	gnl\|CDD\|227309	COG4975, GlcU, Putative glucose uptake permease [Carbohydrate transport and metabolism].	1.5205e-114
CP022582.1\|AXI07051.1\|2424828_2425062_-\|Molybdenum-cofactor-biosynthesis-protein-MoaD	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
CP022582.1\|AXI07053.1\|2425527_2426013_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-MobB	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	9.59347e-51
CP022582.1\|AXI07049.1\|2423180_2424203_-\|Molybdenum-cofactor-biosynthesis-protein-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.12237e-165
CP022582.1\|AXI07043.1\|2414400_2417568_-\|RND-multidrug-efflux-transporter,-Acriflavin-resistance-protein	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
CP022582.1\|AXI07048.1\|2422253_2422604_-\|Transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
CP022582.1\|AXI07040.1\|2412449_2413358_-\|Transporter	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	7.28102e-43
CP022582.1\|AXI07045.1\|2419581_2420346_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
CP022582.1\|AXI07046.1\|2420507_2420948_+\|Transcriptional-regulator,-MarR-family	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15

>CP022582.1|AXI07048.1|2422253_2422604_-|Transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>CP022582.1|AXI07047.1|2421030_2422152_+|Major-facilitator-family-transporter
MYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETDVINKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>CP022582.1|AXI07046.1|2420507_2420948_+|Transcriptional-regulator,-MarR-family
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>CP022582.1|AXI07045.1|2419581_2420346_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>CP022582.1|AXI07044.1|2417684_2418950_-|tRNA-dependent-lipid-II--glycine-ligase-(FmhB)
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYILNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>CP022582.1|AXI07043.1|2414400_2417568_-|RND-multidrug-efflux-transporter,-Acriflavin-resistance-protein
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKALNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHVDGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>CP022582.1|AXI07042.1|2413899_2414217_+|Hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>CP022582.1|AXI07041.1|2413490_2413655_+|Hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>CP022582.1|AXI07040.1|2412449_2413358_-|Transporter
MTEQFTMIILLIALGYFLKRINFIKATDSQVIATLVLNVTLPSLVIVNLNSAELKLSFSILPILMIIYGIVAKMIAVWFFRKYDNHMRGSVGMMTGAMNIGLFAYPLIEVIWPKTGLIYFGMADIGGAFVMFGITYFVGSYFSEGSDQFDFKYLGKKLLQSVPLVTYIVMFILNINHIHLPHVAIDFFSILSHANMPLSMILLGVMLNFTLERKYIPATIKYLCLHYGLALVAGLLVHVLLPVSDDMIKTTLLVTWMFPVGVAIISYGIQFKYRTLPFIGMTTNLTIIISIIILYVYQAVFV
>CP022582.1|AXI07039.1|2410931_2411795_+|glucose-uptake-protein
MQFLDFLIALLPALFWGSVVLINVFVGGGPYNQIRGTTLGALIVGLGLLITGFAKFNNPTVIIVGLISGALWAFGQANQLKSISLIGVSNTMPVSTGMQLVGTTLFSVIFLGEWSSMTQIIFGLIAMILLVTGVALTSLKAKNERQSDNPEFKKAMGILIVSTVGYVGFVVLGDIFGVGGTDALFFQSVGMAIGGFILSMNHKTSLKSTALNLLPGVIWGIGNLFMFYSQPKVGVATSFSLSQLLVIVSTLGGIFILGERKDRRQMTGIWAGIIIIVIAAIILGNLK
>CP022582.1|AXI07049.1|2423180_2424203_-|Molybdenum-cofactor-biosynthesis-protein-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQELYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>CP022582.1|AXI07050.1|2424222_2424822_-|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNIYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>CP022582.1|AXI07051.1|2424828_2425062_-|Molybdenum-cofactor-biosynthesis-protein-MoaD
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>CP022582.1|AXI07052.1|2425067_2425514_-|Molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVIEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>CP022582.1|AXI07053.1|2425527_2426013_-|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-MobB
MILQIVGYKKSGKTTLMRHIVSFLKTHGYTVATIKHHGHAKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRDEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>CP022582.1|AXI07054.1|2426009_2427269_-|Molybdopterin-biosynthesis-protein-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>CP022582.1|AXI07055.1|2427331_2427826_+|Molybdenum-cofactor-biosynthesis-protein-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSGQ
>CP022582.1|AXI07056.1|2427827_2428334_-|Molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFVTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>CP022582.1|AXI07057.1|2428364_2429369_-|Molybdopterin-biosynthesis-protein-MoeB
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDGCIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>CP022582.1|AXI07058.1|2429538_2430144_-|Molybdenum-transport-ATP-binding-protein-ModC
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTTKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSKHIDQLIQTLNINHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP022582_1	1.1\|183224\|33\|CP022582\|CRISPRCasFinder	183224-183256	33	CP022582.1	1451768-1451800	0	1.0
CP022582_4	4.1\|839564\|31\|CP022582\|CRISPRCasFinder	839564-839594	31	CP022582.1	306392-306422	0	1.0
CP022582_5	5.3\|845098\|21\|CP022582\|CRT	845098-845118	21	CP022582.1	845157-845177	0	1.0
CP022582_6	6.1\|852275\|32\|CP022582\|CRISPRCasFinder	852275-852306	32	CP022582.1	84705-84736	0	1.0
CP022582_6	6.1\|852275\|32\|CP022582\|CRISPRCasFinder	852275-852306	32	CP022582.1	888482-888513	0	1.0
CP022582_6	6.1\|852275\|32\|CP022582\|CRISPRCasFinder	852275-852306	32	CP022582.1	1780965-1780996	0	1.0
CP022582_6	6.1\|852275\|32\|CP022582\|CRISPRCasFinder	852275-852306	32	CP022582.1	2197783-2197814	0	1.0
CP022582_6	6.1\|852275\|32\|CP022582\|CRISPRCasFinder	852275-852306	32	CP022582.1	2587720-2587751	0	1.0
CP022582_9	9.1\|2158084\|34\|CP022582\|CRISPRCasFinder	2158084-2158117	34	CP022582.1	839539-839572	0	1.0
CP022582_9	9.1\|2158084\|34\|CP022582\|CRISPRCasFinder	2158084-2158117	34	CP022582.1	1240035-1240068	0	1.0
CP022582_4	4.1\|839564\|31\|CP022582\|CRISPRCasFinder	839564-839594	31	CP022582.1	306337-306367	1	0.968
CP022582_4	4.1\|839564\|31\|CP022582\|CRISPRCasFinder	839564-839594	31	CP022582.1	1800778-1800808	1	0.968
CP022582_5	5.2\|845040\|20\|CP022582\|CRT	845040-845059	20	CP022582.1	2109155-2109174	1	0.95
CP022582_5	5.2\|845040\|20\|CP022582\|CRT	845040-845059	20	CP022582.1	2864135-2864154	1	0.95
CP022582_5	5.3\|845098\|21\|CP022582\|CRT	845098-845118	21	CP022582.1	798855-798875	1	0.952
CP022582_5	5.3\|845098\|21\|CP022582\|CRT	845098-845118	21	CP022582.1	2158150-2158170	1	0.952
CP022582_6	6.1\|852275\|32\|CP022582\|CRISPRCasFinder	852275-852306	32	CP022582.1	1451845-1451876	1	0.969
CP022582_7	7.1\|888176\|34\|CP022582\|CRISPRCasFinder	888176-888209	34	CP022582.1	1451767-1451800	1	0.971
CP022582_8	8.1\|1766322\|33\|CP022582\|CRISPRCasFinder	1766322-1766354	33	CP022582.1	1451768-1451800	1	0.97
CP022582_9	9.1\|2158084\|34\|CP022582\|CRISPRCasFinder	2158084-2158117	34	CP022582.1	1893029-1893062	1	0.971
CP022582_13	13.1\|2422982\|31\|CP022582\|CRISPRCasFinder	2422982-2423012	31	CP022582.1	852225-852255	1	0.968
CP022582_1	1.1\|183224\|33\|CP022582\|CRISPRCasFinder	183224-183256	33	CP022582.1	1540103-1540135	2	0.939
CP022582_5	5.1\|844981\|21\|CP022582\|CRT	844981-845001	21	CP022582.1	673180-673200	2	0.905
CP022582_5	5.1\|844981\|21\|CP022582\|CRT	844981-845001	21	CP022582.1	1245631-1245651	2	0.905
CP022582_5	5.1\|844981\|21\|CP022582\|CRT	844981-845001	21	CP022582.1	1451722-1451742	2	0.905
CP022582_5	5.1\|844981\|21\|CP022582\|CRT	844981-845001	21	CP022582.1	1540161-1540181	2	0.905
CP022582_5	5.1\|844981\|21\|CP022582\|CRT	844981-845001	21	CP022582.1	2098403-2098423	2	0.905
CP022582_5	5.1\|844981\|21\|CP022582\|CRT	844981-845001	21	CP022582.1	2098462-2098482	2	0.905
CP022582_5	5.1\|844981\|21\|CP022582\|CRT	844981-845001	21	CP022582.1	2412195-2412215	2	0.905
CP022582_5	5.2\|845040\|20\|CP022582\|CRT	845040-845059	20	CP022582.1	2044111-2044130	2	0.9
CP022582_9	9.1\|2158084\|34\|CP022582\|CRISPRCasFinder	2158084-2158117	34	CP022582.1	1456141-1456174	2	0.941
CP022582_9	9.1\|2158084\|34\|CP022582\|CRISPRCasFinder	2158084-2158117	34	CP022582.1	2864127-2864160	2	0.941
CP022582_13	13.1\|2422982\|31\|CP022582\|CRISPRCasFinder	2422982-2423012	31	CP022582.1	84711-84741	2	0.935
CP022582_13	13.1\|2422982\|31\|CP022582\|CRISPRCasFinder	2422982-2423012	31	CP022582.1	382188-382218	2	0.935
CP022582_13	13.1\|2422982\|31\|CP022582\|CRISPRCasFinder	2422982-2423012	31	CP022582.1	673184-673214	2	0.935
CP022582_13	13.1\|2422982\|31\|CP022582\|CRISPRCasFinder	2422982-2423012	31	CP022582.1	888488-888518	2	0.935
CP022582_13	13.1\|2422982\|31\|CP022582\|CRISPRCasFinder	2422982-2423012	31	CP022582.1	1098741-1098771	2	0.935
CP022582_13	13.1\|2422982\|31\|CP022582\|CRISPRCasFinder	2422982-2423012	31	CP022582.1	1245635-1245665	2	0.935
CP022582_13	13.1\|2422982\|31\|CP022582\|CRISPRCasFinder	2422982-2423012	31	CP022582.1	1451726-1451756	2	0.935
CP022582_13	13.1\|2422982\|31\|CP022582\|CRISPRCasFinder	2422982-2423012	31	CP022582.1	1540147-1540177	2	0.935
CP022582_13	13.1\|2422982\|31\|CP022582\|CRISPRCasFinder	2422982-2423012	31	CP022582.1	1780960-1780990	2	0.935
CP022582_13	13.1\|2422982\|31\|CP022582\|CRISPRCasFinder	2422982-2423012	31	CP022582.1	2098448-2098478	2	0.935
CP022582_13	13.1\|2422982\|31\|CP022582\|CRISPRCasFinder	2422982-2423012	31	CP022582.1	2412181-2412211	2	0.935
CP022582_13	13.1\|2422982\|31\|CP022582\|CRISPRCasFinder	2422982-2423012	31	CP022582.1	2587726-2587756	2	0.935

1. spacer 1.1|183224|33|CP022582|CRISPRCasFinder matches to position: 1451768-1451800, mismatch: 0, identity: 1.0

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacaaagagaaattggattcccaat	Protospacer
*********************************

2. spacer 4.1|839564|31|CP022582|CRISPRCasFinder matches to position: 306392-306422, mismatch: 0, identity: 1.0

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttgcattgcc	Protospacer
*******************************

3. spacer 5.3|845098|21|CP022582|CRT matches to position: 845157-845177, mismatch: 0, identity: 1.0

attggaaatccaatttctctg	CRISPR spacer
attggaaatccaatttctctg	Protospacer
*********************

4. spacer 6.1|852275|32|CP022582|CRISPRCasFinder matches to position: 84705-84736, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgactttccgc	CRISPR spacer
aacttgcacattattgtaagctgactttccgc	Protospacer
********************************

5. spacer 6.1|852275|32|CP022582|CRISPRCasFinder matches to position: 888482-888513, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgactttccgc	CRISPR spacer
aacttgcacattattgtaagctgactttccgc	Protospacer
********************************

6. spacer 6.1|852275|32|CP022582|CRISPRCasFinder matches to position: 1780965-1780996, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgactttccgc	CRISPR spacer
aacttgcacattattgtaagctgactttccgc	Protospacer
********************************

7. spacer 6.1|852275|32|CP022582|CRISPRCasFinder matches to position: 2197783-2197814, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgactttccgc	CRISPR spacer
aacttgcacattattgtaagctgactttccgc	Protospacer
********************************

8. spacer 6.1|852275|32|CP022582|CRISPRCasFinder matches to position: 2587720-2587751, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgactttccgc	CRISPR spacer
aacttgcacattattgtaagctgactttccgc	Protospacer
********************************

9. spacer 9.1|2158084|34|CP022582|CRISPRCasFinder matches to position: 839539-839572, mismatch: 0, identity: 1.0

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctctgtgttgg	Protospacer
**********************************

10. spacer 9.1|2158084|34|CP022582|CRISPRCasFinder matches to position: 1240035-1240068, mismatch: 0, identity: 1.0

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctctgtgttgg	Protospacer
**********************************

11. spacer 4.1|839564|31|CP022582|CRISPRCasFinder matches to position: 306337-306367, mismatch: 1, identity: 0.968

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttgcattacc	Protospacer
****************************.**

12. spacer 4.1|839564|31|CP022582|CRISPRCasFinder matches to position: 1800778-1800808, mismatch: 1, identity: 0.968

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttccattgcc	Protospacer
*********************** *******

13. spacer 5.2|845040|20|CP022582|CRT matches to position: 2109155-2109174, mismatch: 1, identity: 0.95

tttcttttcgaaattctctt	CRISPR spacer
tttcctttcgaaattctctt	Protospacer
****.***************

14. spacer 5.2|845040|20|CP022582|CRT matches to position: 2864135-2864154, mismatch: 1, identity: 0.95

tttcttttcgaaattctctt	CRISPR spacer
tttcttttcgaaattctttt	Protospacer
*****************.**

15. spacer 5.3|845098|21|CP022582|CRT matches to position: 798855-798875, mismatch: 1, identity: 0.952

attggaaatccaatttctctg	CRISPR spacer
attgggaatccaatttctctg	Protospacer
*****.***************

16. spacer 5.3|845098|21|CP022582|CRT matches to position: 2158150-2158170, mismatch: 1, identity: 0.952

attggaaatccaatttctctg	CRISPR spacer
attgggaatccaatttctctg	Protospacer
*****.***************

17. spacer 6.1|852275|32|CP022582|CRISPRCasFinder matches to position: 1451845-1451876, mismatch: 1, identity: 0.969

aacttgcacattattgtaagctgactttccgc	CRISPR spacer
aacttgcacattattgtaaactgactttccgc	Protospacer
*******************.************

18. spacer 7.1|888176|34|CP022582|CRISPRCasFinder matches to position: 1451767-1451800, mismatch: 1, identity: 0.971

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
****.*****************************

19. spacer 8.1|1766322|33|CP022582|CRISPRCasFinder matches to position: 1451768-1451800, mismatch: 1, identity: 0.97

attgggaatccaatttctctgtgttggggccca	CRISPR spacer
attgggaatccaatttctctttgttggggccca	Protospacer
******************** ************

20. spacer 9.1|2158084|34|CP022582|CRISPRCasFinder matches to position: 1893029-1893062, mismatch: 1, identity: 0.971

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctttgtgttgg	Protospacer
*************************.********

21. spacer 13.1|2422982|31|CP022582|CRISPRCasFinder matches to position: 852225-852255, mismatch: 1, identity: 0.968

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgtcagct	Protospacer
***********************.*******

22. spacer 1.1|183224|33|CP022582|CRISPRCasFinder matches to position: 1540103-1540135, mismatch: 2, identity: 0.939

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tggaccccaacaaagagaaattgtattcccaat	Protospacer
***.******************* *********

23. spacer 5.1|844981|21|CP022582|CRT matches to position: 673180-673200, mismatch: 2, identity: 0.905

ctgacttatcgtaagcttctg	CRISPR spacer
ctgacttttcgtcagcttctg	Protospacer
******* **** ********

24. spacer 5.1|844981|21|CP022582|CRT matches to position: 1245631-1245651, mismatch: 2, identity: 0.905

ctgacttatcgtaagcttctg	CRISPR spacer
ctgacttttcgtcagcttctg	Protospacer
******* **** ********

25. spacer 5.1|844981|21|CP022582|CRT matches to position: 1451722-1451742, mismatch: 2, identity: 0.905

ctgacttatcgtaagcttctg	CRISPR spacer
ctgacttttcgtcagcttctg	Protospacer
******* **** ********

26. spacer 5.1|844981|21|CP022582|CRT matches to position: 1540161-1540181, mismatch: 2, identity: 0.905

ctgacttatcgtaagcttctg	CRISPR spacer
ctgacttttcgtcagcttctg	Protospacer
******* **** ********

27. spacer 5.1|844981|21|CP022582|CRT matches to position: 2098403-2098423, mismatch: 2, identity: 0.905

ctgacttatcgtaagcttctg	CRISPR spacer
ctgacttttcgtcagcttctg	Protospacer
******* **** ********

28. spacer 5.1|844981|21|CP022582|CRT matches to position: 2098462-2098482, mismatch: 2, identity: 0.905

ctgacttatcgtaagcttctg	CRISPR spacer
ctgacttttcgtcagcttctg	Protospacer
******* **** ********

29. spacer 5.1|844981|21|CP022582|CRT matches to position: 2412195-2412215, mismatch: 2, identity: 0.905

ctgacttatcgtaagcttctg	CRISPR spacer
ctgacttttcgtcagcttctg	Protospacer
******* **** ********

30. spacer 5.2|845040|20|CP022582|CRT matches to position: 2044111-2044130, mismatch: 2, identity: 0.9

tttcttttcgaaattctctt	CRISPR spacer
tttcttttcaaaagtctctt	Protospacer
*********.*** ******

31. spacer 9.1|2158084|34|CP022582|CRISPRCasFinder matches to position: 1456141-1456174, mismatch: 2, identity: 0.941

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtggaatttcttatcgaaattctctgtgttgg	Protospacer
****.********* *******************

32. spacer 9.1|2158084|34|CP022582|CRISPRCasFinder matches to position: 2864127-2864160, mismatch: 2, identity: 0.941

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctttttgttgg	Protospacer
*************************.* ******

33. spacer 13.1|2422982|31|CP022582|CRISPRCasFinder matches to position: 84711-84741, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

34. spacer 13.1|2422982|31|CP022582|CRISPRCasFinder matches to position: 382188-382218, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

35. spacer 13.1|2422982|31|CP022582|CRISPRCasFinder matches to position: 673184-673214, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

36. spacer 13.1|2422982|31|CP022582|CRISPRCasFinder matches to position: 888488-888518, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

37. spacer 13.1|2422982|31|CP022582|CRISPRCasFinder matches to position: 1098741-1098771, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

38. spacer 13.1|2422982|31|CP022582|CRISPRCasFinder matches to position: 1245635-1245665, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

39. spacer 13.1|2422982|31|CP022582|CRISPRCasFinder matches to position: 1451726-1451756, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

40. spacer 13.1|2422982|31|CP022582|CRISPRCasFinder matches to position: 1540147-1540177, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

41. spacer 13.1|2422982|31|CP022582|CRISPRCasFinder matches to position: 1780960-1780990, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

42. spacer 13.1|2422982|31|CP022582|CRISPRCasFinder matches to position: 2098448-2098478, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

43. spacer 13.1|2422982|31|CP022582|CRISPRCasFinder matches to position: 2412181-2412211, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

44. spacer 13.1|2422982|31|CP022582|CRISPRCasFinder matches to position: 2587726-2587756, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP022582_12	12.1\|2315008\|34\|CP022582\|CRISPRCasFinder	2315008-2315041	34	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	23034-23067	8	0.765
CP022582_12	12.1\|2315008\|34\|CP022582\|CRISPRCasFinder	2315008-2315041	34	CP030544	Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence	7567-7600	8	0.765

1. spacer 12.1|2315008|34|CP022582|CRISPRCasFinder matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgcatatctttagctttatagcttttatatgct	Protospacer
******************** *.** .*  **

2. spacer 12.1|2315008|34|CP022582|CRISPRCasFinder matches to CP030544 (Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgaataactttagctttattgttataaacagta	Protospacer
*** *** ****************   *** * .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

427245 : 452190

Streptococcus_phage(78.95%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXI05152.1\|427245_428712_+	Inosine-5'-monophosphate dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.2e-96	40.5
AXI05153.1\|428736_430278_+	GMP synthase (glutamine-hydrolyzing)	A0A1V0SH76	Hokovirus	1.2e-23	32.6
AXI05154.1\|430345_431539_-	Integrase, superantigen-encoding pathogenicity islands SaPI	A0A0S2MV79	Bacillus_phage	8.3e-44	34.2
AXI05155.1\|431565_431766_-	hypothetical protein	NA	NA	NA	NA
AXI05156.1\|432263_432494_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	1.0e-27	78.9
AXI05157.1\|432490_432913_-	hypothetical protein	A0A1S5SEW0	Streptococcus_phage	7.5e-48	68.6
AXI05158.1\|433443_433797_+	hypothetical protein	A0A1S5SFA6	Streptococcus_phage	2.2e-53	89.7
AXI05159.1\|434140_436060_-	Tetracycline resistance protein TetM	A0A1S5SF82	Streptococcus_phage	0.0e+00	97.2
AXI05160.1\|436436_437366_-	hypothetical protein	A0A1S5SF22	Streptococcus_phage	1.1e-83	56.6
AXI05161.1\|437382_438405_-	lipoprotein, NLP/P60 family	A0A1S5SEZ8	Streptococcus_phage	2.4e-132	75.5
AXI05162.1\|438401_440429_-	membrane protein, putative	A0A1S5SF30	Streptococcus_phage	5.1e-195	65.3
AXI05163.1\|440425_442879_-	hypothetical protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	78.9
AXI05164.1\|442862_443258_-	hypothetical protein	A0A1S5SEX7	Streptococcus_phage	5.9e-47	72.6
AXI05165.1\|443329_443968_-	hypothetical protein	NA	NA	NA	NA
AXI05166.1\|444023_444524_-	Antirestriction protein	A0A1S5SF25	Streptococcus_phage	1.7e-54	63.0
AXI05167.1\|444584_445364_-	Abortive infection C-terminus	NA	NA	NA	NA
AXI05168.1\|445405_445627_-	Conjugation related protein	A0A1S5SEY0	Streptococcus_phage	3.1e-29	93.2
AXI05169.1\|445623_445914_-	hypothetical protein	NA	NA	NA	NA
AXI05170.1\|445910_447095_-	Transcriptional regulator, Cro/CI family	A0A1S5SEX3	Streptococcus_phage	6.3e-161	68.1
AXI05171.1\|447276_448680_-	hypothetical protein	A0A1S5SFB5	Streptococcus_phage	2.2e-176	66.5
AXI05172.1\|448701_449475_-	hypothetical protein	NA	NA	NA	NA
AXI05173.1\|449484_449862_-	hypothetical protein	A0A1S5SF96	Streptococcus_phage	9.6e-47	76.4
AXI05174.1\|449882_450197_-	hypothetical protein	A0A1S5SF38	Streptococcus_phage	1.2e-42	77.7
AXI05175.1\|450396_452190_-	ATP-dependent DNA helicase UvrD/PcrA	E3T5J8	Cafeteria_roenbergensis_virus	6.9e-26	23.8

DBSCAN-SWA_2

796504 : 811145

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXI05483.1\|796504_797563_+	Biosynthetic Aromatic amino acid aminotransferase beta	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
AXI05484.1\|797901_798444_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
AXI05485.1\|799322_800240_-	Transcription regulator	A0A1V0SBJ0	Catovirus	2.1e-07	22.0
AXI05486.1\|800509_802015_-	Di/tripeptide permease YjdL	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
AXI05487.1\|802355_802856_-	NADPH dependent preQ0 reductase	E7DN65	Pneumococcus_phage	5.9e-52	71.5
AXI05488.1\|802875_803742_-	Integral membrane domain protein	NA	NA	NA	NA
AXI05489.1\|804542_804941_+	Ribonucleotide reduction protein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
AXI05490.1\|804903_807009_+	Ribonucleotide reductase of class Ib(aerobic) alpha subunit	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
AXI05491.1\|807126_808098_+	Ribonucleotide reductase of class Ib(aerobic) beta subunit	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
AXI05492.1\|808472_809444_+	Iron compound ABC uptake transporter permease protein	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
AXI05493.1\|809430_810387_+	Iron compound ABC uptake transporter permease protein	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
AXI05494.1\|810383_811145_+	Iron compound ABC uptake transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6

DBSCAN-SWA_3

896563 : 942563

Staphylococcus_phage(76.81%)

holin,terminase,portal,integrase,tail,capsid

attL 898375:898391|attR 907375:907391

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXI05579.1\|896563_897805_+	SulS subfamily cysteine desulfurase	Q2XUY6	environmental_halophage	8.2e-111	44.8
AXI05580.1\|897794_898259_+	Putative iron-sulfur cluster assembly scaffold protein for SUF system, SufE2	NA	NA	NA	NA
898375:898391	attL	NA	NA	NA	NA
AXI05581.1\|898409_899807_+	Iron-sulfur cluster assembly protein SufB	NA	NA	NA	NA
AXI05582.1\|899874_900924_-\|integrase	Phage integrase	A1KWY3	Staphylococcus_virus	1.6e-203	100.0
AXI05583.1\|901035_901215_+	Phage excisionase	A0EWN7	Staphylococcus_virus	8.3e-25	100.0
AXI05584.1\|901194_902127_-	Hypothetical protein	A0EWN8	Staphylococcus_virus	3.9e-174	100.0
AXI05585.1\|902158_902623_-	Phage protein	A0A2I6PEK4	Staphylococcus_phage	3.6e-80	94.1
AXI05586.1\|902635_902965_-	Phage repressor protein	A0A2I6PEN2	Staphylococcus_phage	3.2e-54	100.0
AXI05587.1\|903125_903317_+	Phage protein	A0A2I6PEL6	Staphylococcus_phage	2.3e-28	100.0
AXI05588.1\|903538_903748_-	Phage protein	W5R9J5	Staphylococcus_phage	1.2e-30	100.0
AXI05589.1\|903804_904584_+	Phage antirepressor protein	M1RZB2	Staphylococcus_phage	4.1e-132	92.6
AXI05590.1\|904584_904809_+	Phage protein	A0A0F6N4M2	Staphylococcus_phage	3.2e-34	100.0
AXI05591.1\|905013_905661_-	Phage protein	S4V9K2	Staphylococcus_phage	2.0e-113	100.0
AXI05592.1\|905731_905953_+	Hypothetical protein	E0Y3P2	Staphylococcus_virus	1.5e-31	100.0
AXI05593.1\|905945_906107_+	DUF1270 domain-containing protein	A0A0E3XBK7	Staphylococcus_phage	4.3e-20	96.2
AXI05594.1\|906199_906502_+	Hypothetical protein	A0A0F6N3N3	Staphylococcus_phage	1.4e-48	100.0
AXI05595.1\|906506_906767_+	Phage protein	C8CGY6	Staphylococcus_phage	8.9e-44	100.0
AXI05596.1\|906776_906998_+	Hypothetical protein	A7TWM6	Staphylococcus_phage	3.2e-34	100.0
AXI05597.1\|906990_907113_+	Phage protein	NA	NA	NA	NA
AXI05598.1\|907132_907615_+	Phage protein	A0A2H4PQQ6	Staphylococcus_phage	1.0e-85	99.4
907375:907391	attR	NA	NA	NA	NA
AXI05599.1\|907614_908040_+	Single-stranded DNA-binding protein	B7T0A5	Staphylococcus_virus	2.1e-58	88.7
AXI05600.1\|908050_908602_+	HNH homing endonuclease	A0A2H4PQR4	Staphylococcus_phage	5.1e-105	98.9
AXI05601.1\|908602_909277_+	Hypothetical protein	R4IH15	Staphylococcus_phage	1.5e-127	97.8
AXI05602.1\|909416_909698_-	hypothetical protein	A0A1W6JPU7	Staphylococcus_phage	2.6e-49	100.0
AXI05603.1\|909762_910494_+	hypothetical protein	A0A1J0MGB2	Staphylococcus_phage	9.8e-80	78.8
AXI05604.1\|910506_911292_+	DNA replication protein dnaC	A0A0H4J332	Staphylococcus_phage	1.9e-145	100.0
AXI05605.1\|911459_911681_+	Phage protein	A0A0H3U2V4	Staphylococcus_phage	2.2e-35	100.0
AXI05606.1\|911690_912095_+	Phage protein	A7TWN5	Staphylococcus_phage	7.1e-72	100.0
AXI05607.1\|912099_912285_+	Hypothetical protein	W5R8N4	Staphylococcus_phage	1.4e-27	100.0
AXI05608.1\|912285_912657_+	Hypothetical protein	A7TWN6	Staphylococcus_phage	4.0e-53	95.9
AXI05609.1\|912657_912906_+	Phage protein	S4V683	Staphylococcus_phage	8.8e-41	97.6
AXI05610.1\|912920_913169_+	DUF1024 domain-containing protein	A0A2H4PQK1	Staphylococcus_phage	1.7e-36	93.9
AXI05611.1\|913161_913698_+	Dimeric dUTPase	A0A1P8L6E0	Staphylococcus_phage	2.1e-95	100.0
AXI05612.1\|913734_913941_+	DUF1381 domain-containing protein	A0A1W6JPM8	Staphylococcus_phage	4.9e-21	100.0
AXI05613.1\|913937_914132_+	Phage protein	S4SX95	Staphylococcus_phage	7.9e-29	100.0
AXI05614.1\|914128_914332_+	Phage protein	A0A0N9BAX5	Staphylococcus_phage	5.2e-31	100.0
AXI05615.1\|914324_914561_+	Hypothetical protein	S4SWB7	Staphylococcus_phage	1.6e-36	100.0
AXI05616.1\|914553_914937_+	Transcriptional activator rinB, phage associated	Q4ZBS3	Staphylococcus_virus	3.3e-63	99.2
AXI05617.1\|914936_915110_+	Transcriptional activator rinB, phage associated	S4SVE4	Staphylococcus_phage	1.1e-21	98.2
AXI05618.1\|915110_915257_+	Phage protein	Q4ZDN7	Staphylococcus_virus	1.3e-15	100.0
AXI05619.1\|915271_915691_+	Integrase regulator RinA	I1W651	Staphylococcus_phage	8.1e-71	100.0
AXI05620.1\|915877_916318_+\|terminase	Phage terminase, small subunit	I1W650	Staphylococcus_phage	2.4e-73	99.3
AXI05621.1\|916304_917582_+\|terminase	Phage terminase, large subunit	A0EWS5	Staphylococcus_virus	5.1e-249	99.8
AXI05622.1\|917592_919128_+\|portal	Phage portal protein	Q4ZDV9	Staphylococcus_virus	9.3e-290	99.4
AXI05623.1\|919134_920130_+	Phage protein	E0Y3K7	Staphylococcus_virus	3.4e-184	100.0
AXI05624.1\|920202_920373_+	Phage protein	Q4ZDF2	Staphylococcus_virus	3.3e-23	100.0
AXI05625.1\|920507_921122_+\|capsid	Phage capsid and scaffold	A0EWS9	Staphylococcus_virus	4.9e-40	100.0
AXI05626.1\|921135_921444_+\|capsid	Phage major capsid protein	Q8SDU5	Staphylococcus_phage	1.0e-46	100.0
AXI05627.1\|921440_922109_+\|capsid	Phage major capsid protein	S4V686	Staphylococcus_phage	6.1e-121	100.0
AXI05628.1\|922130_922418_+	Phage transcriptional terminator	S4V6D9	Staphylococcus_phage	6.8e-45	98.9
AXI05629.1\|922426_922759_+	Phage protein	A0A0F6N3F4	Staphylococcus_phage	5.5e-54	100.0
AXI05630.1\|922755_923058_+	hypothetical protein	S4V7K8	Staphylococcus_phage	1.1e-50	100.0
AXI05631.1\|923057_923405_+	Phage protein	S4V987	Staphylococcus_phage	3.1e-60	100.0
AXI05632.1\|923416_923800_+	Phage protein	A0A0F6N3L1	Staphylococcus_phage	1.5e-68	100.0
AXI05633.1\|923818_924400_+\|tail	Phage tail protein	A0A0F6N3L8	Staphylococcus_phage	4.9e-106	100.0
AXI05634.1\|924461_924827_+	Phage protein	S4V9M6	Staphylococcus_phage	2.8e-59	100.0
AXI05635.1\|924856_925201_+	Hypothetical protein	A0A0F6N3F7	Staphylococcus_phage	2.5e-57	100.0
AXI05636.1\|925217_928682_+	Tape measure protein	S4V989	Staphylococcus_phage	5.8e-271	100.0
AXI05637.1\|928694_929642_+\|tail	phage tail family protein	S4V688	Staphylococcus_phage	3.6e-183	100.0
AXI05638.1\|929650_931552_+	Phage minor structural protein	Q4ZDD8	Staphylococcus_virus	0.0e+00	100.0
AXI05639.1\|931566_932061_+	Putative major teichoic acid biosynthesis protein C	I1W633	Staphylococcus_phage	4.1e-90	100.0
AXI05640.1\|932097_933477_+	Putative major teichoic acid biosynthesis protein C	A1KX41	Staphylococcus_virus	1.3e-279	99.8
AXI05641.1\|933476_935300_+	hypothetical protein	W5R8J5	Staphylococcus_phage	7.4e-294	99.2
AXI05642.1\|935299_935677_+	Phage protein	Q9FZY7	Staphylococcus_virus	3.4e-60	99.2
AXI05643.1\|935680_935854_+	XkdX family protein	A0A0F6N3L7	Staphylococcus_phage	6.6e-27	100.0
AXI05644.1\|935894_936194_+	Phage protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
AXI05645.1\|936330_938229_+	Phage lysin, N-acetylmuramoyl-L-alanine amidase	Q8SDT1	Staphylococcus_phage	0.0e+00	99.8
AXI05646.1\|938241_939480_+	Tail fiber protein	A0A0F6N3G7	Staphylococcus_phage	2.7e-207	98.1
AXI05647.1\|939485_939881_+	Phage protein	A0A0E3XBL9	Staphylococcus_phage	1.4e-67	97.7
AXI05648.1\|939936_940374_+\|holin	Phage holin	Q8SDS8	Staphylococcus_phage	6.9e-73	99.3
AXI05649.1\|940354_941800_+	Phage lysin, N-acetylmuramoyl-L-alanine amidase	Q08JW9	Staphylococcus_phage	1.8e-295	99.8
AXI05650.1\|942362_942563_+	hypothetical protein	W5R9N2	Staphylococcus_phage	3.7e-29	100.0

DBSCAN-SWA_4

1100313 : 1113950

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXI05795.1\|1100313_1100733_+	AIR carboxylase	A0A2P0VNU7	Tetraselmis_virus	1.2e-18	45.8
AXI05796.1\|1100719_1101844_+	Phosphoribosylaminoimidazole carboxylase ATPase subunit	NA	NA	NA	NA
AXI05797.1\|1101847_1102552_+	Phosphoribosylaminoimidazole-succinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
AXI05798.1\|1102551_1102815_+	Phosphoribosylformylglycinamidine synthase, PurS subunit	NA	NA	NA	NA
AXI05799.1\|1102816_1103488_+	Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit	NA	NA	NA	NA
AXI05800.1\|1103480_1105670_+	Phosphoribosylformylglycinamidine synthase, synthetase subunit	A6N228	Microbacterium_phage	3.5e-141	39.8
AXI05801.1\|1105648_1107133_+	Amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.9e-45	31.7
AXI05802.1\|1107125_1107848_+	Phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F0L1	Synechococcus_phage	6.0e-37	44.8
AXI05803.1\|1107844_1108153_+	Phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	5.0e-17	43.0
AXI05804.1\|1108155_1108374_+	Phosphoribosylglycinamide formyltransferase	NA	NA	NA	NA
AXI05805.1\|1108424_1108721_+	Phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	9.6e-18	49.5
AXI05806.1\|1108735_1110214_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.2e-77	51.8
AXI05807.1\|1110235_1111483_+	Phosphoribosylamine--glycine ligase	NA	NA	NA	NA
AXI05808.1\|1111750_1112557_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
AXI05809.1\|1112549_1113950_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-10	26.3

DBSCAN-SWA_5

1160401 : 1243354

103

Staphylococcus_phage(91.55%)

transposase,holin,terminase,portal,tRNA,tail,capsid,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXI05856.1\|1160401_1160884_+	Phosphopantetheine adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.6e-28	46.2
AXI05857.1\|1160945_1162085_-	UPF0348 protein family	NA	NA	NA	NA
AXI05858.1\|1162211_1162769_+	protein in cluster with ribosomal protein L32p, Firmicutes subfamily	NA	NA	NA	NA
AXI05859.1\|1162848_1163022_+	LSU ribosomal protein L32p	NA	NA	NA	NA
AXI05860.1\|1163138_1164524_-	Phage DNA invertase	I1W625	Staphylococcus_phage	2.5e-265	100.0
AXI05861.1\|1164730_1165411_-	Pathogenicity island SaPIn2	A0A2H4PQQ5	Staphylococcus_phage	5.1e-123	100.0
AXI05862.1\|1165442_1166168_-	hypothetical protein	A0A0F6N4L7	Staphylococcus_phage	9.9e-125	100.0
AXI05863.1\|1166195_1166858_-	ImmA/IrrE family metallo-endopeptidase	A0A0F6N3H6	Staphylococcus_phage	1.6e-121	100.0
AXI05864.1\|1166887_1167220_-	Phage transcriptional regulator, Cro/CI family	R4IH08	Staphylococcus_phage	7.6e-56	99.1
AXI05865.1\|1167482_1167677_+	Phage repressor	A0A0F6N3M9	Staphylococcus_phage	1.1e-25	100.0
AXI05866.1\|1167676_1168441_+	Phage antirepressor protein	R4IFK0	Staphylococcus_phage	2.7e-141	99.6
AXI05867.1\|1168457_1168652_+	hypothetical protein	E9LT75	Staphylococcus_phage	1.2e-29	100.0
AXI05868.1\|1168704_1168881_+	Phage protein	S4SVC9	Staphylococcus_phage	9.7e-26	100.0
AXI05869.1\|1168855_1169086_-	hypothetical protein	R4IG40	Staphylococcus_phage	2.3e-35	100.0
AXI05870.1\|1169265_1169433_+	DUF1270 domain-containing protein	S4V7J2	Staphylococcus_phage	9.5e-23	100.0
AXI05871.1\|1169433_1169754_+	hypothetical protein	S4V968	Staphylococcus_phage	4.8e-55	100.0
AXI05872.1\|1169847_1170108_+	DUF1108 domain-containing protein	A0A059T5A3	Staphylococcus_phage	1.2e-43	100.0
AXI05873.1\|1170116_1170380_+	Phage protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
AXI05874.1\|1170388_1172332_+	ATPase involved in DNA repair, phage associated	S4V9K6	Staphylococcus_phage	0.0e+00	100.0
AXI05875.1\|1172333_1173254_+	Recombinational DNA repair protein RecT (prophage associated)	A0A2I6PDH5	Staphylococcus_phage	2.3e-166	100.0
AXI05876.1\|1173466_1173952_+	Metallo-beta-lactamase superfamily domain protein in prophage	S4V971	Staphylococcus_phage	9.4e-87	100.0
AXI05877.1\|1173952_1174423_+	Single-stranded DNA-binding protein	S4V682	Staphylococcus_phage	2.6e-81	100.0
AXI05878.1\|1174452_1175340_+	Phage replication initiation protein	S4V6D4	Staphylococcus_phage	3.2e-141	99.7
AXI05879.1\|1175346_1175565_+	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	1.4e-37	100.0
AXI05880.1\|1175573_1175978_+	Phage Holliday junction resolvase	S4V7J7	Staphylococcus_phage	3.8e-73	100.0
AXI05881.1\|1175990_1176368_+	phage protein	S4V974	Staphylococcus_phage	1.6e-54	100.0
AXI05882.1\|1176452_1176617_+	Phage protein	S4SVD3	Staphylococcus_phage	7.6e-25	98.1
AXI05883.1\|1176629_1177031_+	Phage protein	S4V6D5	Staphylococcus_phage	6.6e-70	100.0
AXI05884.1\|1177027_1177312_+	Phage protein	S4V9L1	Staphylococcus_phage	3.2e-47	100.0
AXI05885.1\|1177304_1177553_+	hypothetical protein	S4V7K0	Staphylococcus_phage	4.1e-38	100.0
AXI05886.1\|1177545_1178082_+	Dimeric dUTPase	S4V978	Staphylococcus_phage	9.4e-96	100.0
AXI05887.1\|1178118_1178292_+	hypothetical protein	S4SVD5	Staphylococcus_phage	3.6e-25	100.0
AXI05888.1\|1178308_1178515_+	DUF1381 domain-containing protein	A0A1W6JPM8	Staphylococcus_phage	4.9e-21	100.0
AXI05889.1\|1178511_1178706_+	phage protein	S4SX95	Staphylococcus_phage	7.9e-29	100.0
AXI05890.1\|1178702_1178906_+	Phage protein	A0A0N9BAX5	Staphylococcus_phage	5.2e-31	100.0
AXI05891.1\|1178898_1179135_+	Hypothetical protein	S4SWB7	Staphylococcus_phage	1.6e-36	100.0
AXI05892.1\|1179127_1179511_+	Transcriptional activator rinB, phage associated	Q4ZBS3	Staphylococcus_virus	3.3e-63	99.2
AXI05893.1\|1179510_1179684_+	Transcriptional activator rinB, phage associated	S4SVE4	Staphylococcus_phage	1.1e-21	98.2
AXI05894.1\|1179684_1179831_+	Phage protein	S4V9L4	Staphylococcus_phage	1.7e-15	100.0
AXI05895.1\|1179854_1180277_+	Mobile element protein	Q4ZBJ7	Staphylococcus_phage	1.2e-74	100.0
AXI05896.1\|1180604_1181099_+	Terminase small subunit	R4IH30	Staphylococcus_phage	1.1e-74	100.0
AXI05897.1\|1181091_1182300_+\|terminase	Phage terminase, large subunit	R4IG95	Staphylococcus_phage	6.1e-236	100.0
AXI05898.1\|1182313_1183732_+\|portal	Phage portal protein	R4IFL5	Staphylococcus_phage	1.0e-274	100.0
AXI05899.1\|1183688_1184651_+\|capsid	Phage minor capsid protein	R4II65	Staphylococcus_phage	4.6e-178	100.0
AXI05900.1\|1184748_1185345_+\|capsid	Phage capsid and scaffold	R4IG73	Staphylococcus_phage	5.6e-73	100.0
AXI05901.1\|1185365_1186190_+\|capsid	Phage major capsid protein	R4IH32	Staphylococcus_phage	5.6e-148	100.0
AXI05902.1\|1186206_1186533_+	Phage transcriptional terminator	A0A0E3TAL3	Staphylococcus_phage	4.3e-51	100.0
AXI05903.1\|1186532_1186847_+\|capsid	Phage capsid and scaffold	R4IFL8	Staphylococcus_phage	4.0e-54	100.0
AXI05904.1\|1186839_1187175_+\|head,tail	Phage head-tail adaptor	A0A2H4PQL0	Staphylococcus_phage	3.0e-60	100.0
AXI05905.1\|1187224_1187575_+\|capsid	Phage capsid and scaffold	R4IG77	Staphylococcus_phage	3.6e-64	100.0
AXI05906.1\|1187587_1188025_+	Phage protein	A0A0E3T9M9	Staphylococcus_phage	2.1e-77	100.0
AXI05907.1\|1188011_1188572_+	Phage protein	A0A0H4ITY2	Staphylococcus_phage	5.9e-101	100.0
AXI05908.1\|1188633_1189128_+	Phage protein	R4IFM1	Staphylococcus_phage	4.3e-87	100.0
AXI05909.1\|1189196_1189490_+	Phage protein	A0A2H4PQL5	Staphylococcus_phage	7.5e-47	100.0
AXI05910.1\|1189492_1192462_+\|tail	Phage tail length tape-measure protein	R4IG82	Staphylococcus_phage	5.3e-281	100.0
AXI05911.1\|1192476_1193412_+\|tail	Phage tail protein	R4IH41	Staphylococcus_phage	8.2e-180	100.0
AXI05912.1\|1193422_1195309_+	Phage minor structural protein	R4IGA4	Staphylococcus_phage	0.0e+00	99.8
AXI05913.1\|1195321_1197220_+	Putative major teichoic acid biosynthesis protein C	R4IFM4	Staphylococcus_phage	0.0e+00	100.0
AXI05914.1\|1197219_1199043_+	hypothetical protein	A0A0H4ISS3	Staphylococcus_phage	0.0e+00	99.2
AXI05915.1\|1199042_1199450_+	Phage protein	R4IG87	Staphylococcus_phage	2.9e-57	100.0
AXI05916.1\|1199421_1199598_+	phage uncharacterized protein, XkdX family	Q8LTH6	Staphylococcus_phage	6.1e-28	100.0
AXI05917.1\|1199638_1199857_+	phage protein	Q8LTH5	Staphylococcus_phage	6.4e-27	92.6
AXI05918.1\|1200073_1200184_+	cell wall hydrolase	A7VMY9	Staphylococcus_phage	2.0e-13	97.2
AXI05919.1\|1200429_1201050_+	Phage protein	A0A2H4J2S8	uncultured_Caudovirales_phage	4.3e-36	43.4
AXI05920.1\|1201235_1202930_+	Phage lysin, N-acetylmuramoyl-L-alanine amidase	A0A2I6PCX0	Staphylococcus_phage	0.0e+00	99.3
AXI05921.1\|1202942_1204115_+	Tail fiber protein	S4SUQ8	Staphylococcus_phage	9.2e-197	99.2
AXI05922.1\|1204120_1204516_+	Phage protein	S4SWE0	Staphylococcus_phage	1.6e-68	99.2
AXI05923.1\|1204571_1205009_+\|holin	Phage holin	S4SVG2	Staphylococcus_phage	2.4e-73	100.0
AXI05924.1\|1204989_1206435_+	Phage lysin, N-acetylmuramoyl-L-alanine amidase	B2ZZ06	Staphylococcus_phage	1.7e-293	99.0
AXI05925.1\|1206997_1207198_+	hypothetical protein	W5R9N2	Staphylococcus_phage	3.7e-29	100.0
AXI05926.1\|1207608_1209546_-	Cell surface receptor IsdB for hemoglobin and hemoglobin-haptoglobin complexes	NA	NA	NA	NA
AXI05927.1\|1209748_1210801_-	Cell surface protein IsdA, transfers heme from hemoglobin to apo-IsdC	NA	NA	NA	NA
AXI05928.1\|1211009_1211693_+	NPQTN cell wall anchored protein IsdC	NA	NA	NA	NA
AXI05929.1\|1211692_1212769_+	Heme transporter IsdDEF, membrane component IsdD	NA	NA	NA	NA
AXI05930.1\|1212897_1213644_+	Heme transporter IsdDEF, lipoprotein IsdE	NA	NA	NA	NA
AXI05931.1\|1213656_1214622_+	FecCD transport family	NA	NA	NA	NA
AXI05932.1\|1214683_1215418_+	NPQTN specific sortase B	NA	NA	NA	NA
AXI05933.1\|1215436_1215760_+	Heme-degrading monooxygenase IsdI	NA	NA	NA	NA
AXI05934.1\|1216143_1216884_+	rRNA methylase	NA	NA	NA	NA
AXI05935.1\|1217263_1218322_+\|tRNA	Phenylalanyl-tRNA synthetase alpha chain	A0A2I2L4E3	Orpheovirus	1.9e-31	35.5
AXI05936.1\|1218321_1220724_+\|tRNA	Phenylalanyl-tRNA synthetase beta chain	NA	NA	NA	NA
AXI05937.1\|1221155_1222094_-	Ribonuclease HIII	NA	NA	NA	NA
AXI05938.1\|1222463_1222730_+	Z-ring-associated protein	NA	NA	NA	NA
AXI05939.1\|1222730_1223252_+	Colicin V production protein	NA	NA	NA	NA
AXI05940.1\|1223324_1225037_+	DNA polymerase X family	A0A2H4UV14	Bodo_saltans_virus	6.8e-15	24.0
AXI05941.1\|1225046_1227395_+	Recombination inhibitory protein MutS2	F2QAF8	Phaeocystis_pouchetii_virus	3.2e-15	25.4
AXI05942.1\|1227567_1227882_+	Thioredoxin	A0A1X9I9P5	Staphylococcus_phage	6.6e-25	46.6
AXI05943.1\|1228205_1229987_+	Excinuclease ABC subunit C	NA	NA	NA	NA
AXI05944.1\|1230310_1230925_+	Succinate dehydrogenase cytochrome b558 subunit	NA	NA	NA	NA
AXI05945.1\|1230976_1232743_+	Succinate dehydrogenase flavoprotein subunit	NA	NA	NA	NA
AXI05946.1\|1232742_1233558_+	Succinate dehydrogenase iron-sulfur protein	NA	NA	NA	NA
AXI05947.1\|1233793_1234594_+	Glutamate racemase	NA	NA	NA	NA
AXI05948.1\|1234605_1235193_+	Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific)	NA	NA	NA	NA
AXI05949.1\|1235185_1235689_+	phosphoesterase	NA	NA	NA	NA
AXI05950.1\|1236177_1236507_+	Hypothetical protein	NA	NA	NA	NA
AXI05951.1\|1236875_1237277_-	hypothetical protein	NA	NA	NA	NA
AXI05952.1\|1237946_1238453_+	hypothetical protein	NA	NA	NA	NA
AXI05953.1\|1238712_1239210_+	Extracellular fibrinogen-binding protein Efb	NA	NA	NA	NA
AXI05954.1\|1239359_1239710_+	fibrinogen-binding protein	NA	NA	NA	NA
AXI05955.1\|1240071_1240269_+	hypothetical protein	NA	NA	NA	NA
AXI05956.1\|1240475_1240661_-	hypothetical protein	NA	NA	NA	NA
AXI05957.1\|1241282_1241516_-	hypothetical protein	NA	NA	NA	NA
AXI05958.1\|1242034_1243354_+\|transposase	zinc-finger of transposase IS204/IS1001/IS1096/IS1165	NA	NA	NA	NA

DBSCAN-SWA_6

1411943 : 1416622

Staphylococcus_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXI06107.1\|1411943_1412141_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	9.9e-11	50.0
AXI06108.1\|1412839_1413052_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	4.8e-19	72.5
AXI06109.1\|1413345_1413552_+	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	1.3e-13	59.7
AXI06110.1\|1414785_1414971_+	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.4e-19	78.7
AXI06111.1\|1415713_1415965_+	hypothetical protein	NA	NA	NA	NA
AXI06112.1\|1416010_1416247_+	Phage protein	Q4ZE35	Staphylococcus_virus	2.3e-22	70.6
AXI06113.1\|1416328_1416622_+	hypothetical protein	A0A1J0MFV1	Staphylococcus_phage	1.4e-05	33.3

DBSCAN-SWA_7

1594425 : 1681008

101

Staphylococcus_phage(81.58%)

holin,terminase,portal,protease,tRNA,integrase,tail,capsid

attL 1630704:1630729|attR 1675405:1675430

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXI06256.1\|1594425_1595718_-\|tRNA	Asparaginyl-tRNA synthetase	M1PB22	Moumouvirus	8.7e-55	31.3
AXI06257.1\|1596039_1598733_-	DinG family ATP-dependent helicase YoaA	A0A1X9I5C8	Streptococcus_phage	8.2e-47	34.4
AXI06258.1\|1598756_1599728_-	Biotin operon repressor / Biotin-protein ligase	NA	NA	NA	NA
AXI06259.1\|1599714_1600917_-\|tRNA	tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	4.2e-35	43.3
AXI06260.1\|1600921_1602064_-	Glycosyl transferase, group 1 family protein	NA	NA	NA	NA
AXI06261.1\|1602307_1602625_-	MazG nucleotide pyrophosphohydrolase	NA	NA	NA	NA
AXI06262.1\|1602960_1603659_-	putative metal-dependent peptidase	NA	NA	NA	NA
AXI06263.1\|1603712_1604300_-	DUF1405 domain-containing protein	NA	NA	NA	NA
AXI06264.1\|1604289_1604865_-	hypothetical protein	G3MAV7	Bacillus_virus	2.1e-08	27.2
AXI06265.1\|1604878_1606123_-	TPR-repeat-containing protein, putative component of Menaquinone-cytochrome C reductase	NA	NA	NA	NA
AXI06266.1\|1606129_1607428_-	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	NA	NA	NA	NA
AXI06267.1\|1607437_1608502_-	3-dehydroquinate synthase	NA	NA	NA	NA
AXI06268.1\|1608527_1609694_-	Chorismate synthase	A0A291AU41	Pandoravirus	5.8e-34	31.8
AXI06269.1\|1610078_1610279_-	hypothetical protein	NA	NA	NA	NA
AXI06270.1\|1610487_1610937_-	Nucleoside diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
AXI06271.1\|1611028_1611988_-	Heptaprenyl diphosphate synthase component II	A0A1V0SE37	Indivirus	1.3e-10	24.4
AXI06272.1\|1611989_1612715_-	2-heptaprenyl-1,4-naphthoquinone methyltransferase	NA	NA	NA	NA
AXI06273.1\|1612717_1613290_-	Heptaprenyl diphosphate synthase component I	NA	NA	NA	NA
AXI06274.1\|1613720_1613993_-	DNA-binding protein HBsu	A7KV42	Bacillus_phage	4.2e-28	73.3
AXI06275.1\|1614163_1615162_-	Glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
AXI06276.1\|1615178_1616489_-	GTP-binding protein EngA	NA	NA	NA	NA
AXI06277.1\|1616710_1617886_-	SSU ribosomal protein S1p	NA	NA	NA	NA
AXI06278.1\|1618597_1619257_-	Cytidylate kinase	NA	NA	NA	NA
AXI06279.1\|1619333_1620302_+	L-asparaginase	NA	NA	NA	NA
AXI06280.1\|1620416_1621403_-	Thioredoxin reductase	NA	NA	NA	NA
AXI06281.1\|1621804_1623265_-	Elastin binding protein EbpS	NA	NA	NA	NA
AXI06282.1\|1623417_1624797_-	ATP-dependent DNA helicase RecS (RecQ family)	A0A2P1EM61	Moumouvirus	1.4e-55	33.6
AXI06283.1\|1624786_1625740_-	hypothetical protein	NA	NA	NA	NA
AXI06284.1\|1625847_1626096_+	4Fe-4S single cluster domain of Ferredoxin I	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
AXI06285.1\|1626201_1626747_-	Substrate-specific component RibU of riboflavin ECF transporter	NA	NA	NA	NA
AXI06286.1\|1627148_1628105_-	hypothetical protein	NA	NA	NA	NA
AXI06287.1\|1628245_1628500_-	hypothetical protein	NA	NA	NA	NA
AXI06288.1\|1628575_1629472_-	hypothetical protein	NA	NA	NA	NA
AXI06289.1\|1629529_1630435_-	hypothetical protein	NA	NA	NA	NA
AXI06290.1\|1630524_1630740_-	hypothetical protein	A0ZS61	Staphylococcus_virus	2.0e-25	100.0
1630704:1630729	attL	NA	NA	NA	NA
AXI06291.1\|1631461_1632916_-	Phage lysin, N-acetylmuramoyl-L-alanine amidase	U5U7D2	Staphylococcus_phage	2.6e-289	100.0
AXI06292.1\|1632926_1633229_-\|holin	Phage holin	A0A2I6PET6	Staphylococcus_phage	7.0e-48	100.0
AXI06293.1\|1633364_1633664_-	Phage protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
AXI06294.1\|1633709_1633874_-	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
AXI06295.1\|1633866_1634256_-	Phage protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
AXI06296.1\|1634255_1635722_-	Phage protein	M1TB09	Staphylococcus_phage	1.0e-253	99.8
AXI06297.1\|1635721_1637632_-	Putative major teichoic acid biosynthesis protein C	U5U4Q1	Staphylococcus_phage	0.0e+00	100.0
AXI06298.1\|1637647_1637938_-	hypothetical protein	U5U457	Staphylococcus_phage	2.1e-49	100.0
AXI06299.1\|1637937_1639521_-\|tail	Phage tail fiber	A0A2I6PEQ5	Staphylococcus_phage	9.3e-309	100.0
AXI06300.1\|1639529_1640354_-\|tail	Phage tail fiber	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
AXI06301.1\|1640353_1646554_-\|tail	Phage tail length tape-measure protein	U5U762	Staphylococcus_phage	0.0e+00	99.7
AXI06302.1\|1646567_1646726_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
AXI06303.1\|1646776_1647118_-	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.5e-54	100.0
AXI06304.1\|1647175_1647631_-\|tail	Phage major tail protein	A0A2I6PF45	Staphylococcus_phage	1.3e-77	100.0
AXI06305.1\|1647722_1648364_-\|tail	Phage major tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
AXI06306.1\|1648398_1648794_-	DUF3168 domain-containing protein	A0A2I6PEQ4	Staphylococcus_phage	8.8e-67	100.0
AXI06307.1\|1648794_1649196_-	hypothetical protein	A0A2I6PF54	Staphylococcus_phage	8.1e-68	100.0
AXI06308.1\|1649192_1649525_-	Phage protein	A0A2I6PES3	Staphylococcus_phage	4.1e-57	100.0
AXI06309.1\|1649536_1649815_-	hypothetical protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
AXI06310.1\|1649883_1651047_-\|capsid	Phage major capsid protein	A0A2I6PEQ3	Staphylococcus_phage	1.2e-217	100.0
AXI06311.1\|1651058_1651832_-\|protease	Prophage Clp protease-like protein	A0A2I6PEQ7	Staphylococcus_phage	2.4e-137	100.0
AXI06312.1\|1651815_1653054_-\|portal	Phage portal protein	A0A2K9VBP0	Staphylococcus_phage	6.9e-235	100.0
AXI06313.1\|1653058_1654750_-\|terminase	Phage terminase, large subunit	A0A2K9VBQ1	Staphylococcus_phage	0.0e+00	100.0
AXI06314.1\|1654739_1655045_-\|terminase	Phage terminase small subunit	U5U414	Staphylococcus_phage	2.9e-49	100.0
AXI06315.1\|1655169_1655490_-	Phage-associated homing endonuclease	A0A2K9VBV6	Staphylococcus_phage	3.0e-57	100.0
AXI06316.1\|1655646_1656084_-	Phage regulatory protein	A0A2K9VBV2	Staphylococcus_phage	6.1e-77	100.0
AXI06317.1\|1656096_1657455_-	DNA helicase, phage-associated	A0A1X9IH01	Staphylococcus_phage	1.6e-261	100.0
AXI06318.1\|1657444_1657735_-	Phage protein	U5U7A3	Staphylococcus_phage	4.9e-51	100.0
AXI06319.1\|1657929_1658052_+	Phage protein	Q4ZCF9	Staphylococcus_virus	6.9e-15	95.0
AXI06320.1\|1658075_1660523_-	DNA primase, phage associated	A0A2I6PEP4	Staphylococcus_phage	0.0e+00	100.0
AXI06321.1\|1660810_1661011_-	Phage protein	A0A2I6PEP5	Staphylococcus_phage	4.9e-26	100.0
AXI06322.1\|1661078_1661231_-	Transcriptional activator rinB, phage associated	A0A2I6PEM5	Staphylococcus_phage	2.0e-19	100.0
AXI06323.1\|1661227_1661434_-	DUF1381 domain-containing protein	S4V684	Staphylococcus_phage	7.6e-30	100.0
AXI06324.1\|1661470_1662007_-	Dimeric dUTPase	A0A2K9VBU6	Staphylococcus_phage	3.0e-94	98.9
AXI06325.1\|1661999_1662248_-	Phage protein	S4V7K0	Staphylococcus_phage	4.1e-38	100.0
AXI06326.1\|1662240_1662549_-	Phage protein	U5U489	Staphylococcus_phage	2.8e-52	100.0
AXI06327.1\|1662545_1662893_-	Phage protein	D2JGL4	Staphylococcus_phage	5.9e-59	100.0
AXI06328.1\|1662889_1663270_-	Phage protein	A0A2K9VBT5	Staphylococcus_phage	8.4e-67	100.0
AXI06329.1\|1663272_1663479_-	Phage protein	A0A2K9VBT9	Staphylococcus_phage	3.0e-34	100.0
AXI06330.1\|1663492_1663735_-	Phage protein	A0A2K9VBX5	Staphylococcus_phage	1.1e-40	100.0
AXI06331.1\|1663740_1663995_-	Phage protein	A0A2K9VBW1	Staphylococcus_phage	1.6e-42	100.0
AXI06332.1\|1663991_1664396_-	Phage protein	A0A2K9VBY6	Staphylococcus_phage	3.3e-69	100.0
AXI06333.1\|1664395_1664581_-	Phage protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
AXI06334.1\|1664593_1666555_-	DNA polymerase I	A0A2K9VBT3	Staphylococcus_phage	0.0e+00	100.0
AXI06335.1\|1666613_1667171_-	Phage protein	A0A2K9VBT2	Staphylococcus_phage	1.8e-97	100.0
AXI06336.1\|1667196_1668363_-	Phage protein	A0A2K9VBU5	Staphylococcus_phage	7.0e-221	100.0
AXI06337.1\|1668359_1668722_-	Phage protein	A0A2K9VBV1	Staphylococcus_phage	6.4e-56	100.0
AXI06338.1\|1668736_1669060_-	Phage protein	A7TWG2	Staphylococcus_phage	5.0e-52	100.0
AXI06339.1\|1669138_1669300_-	DUF1270 domain-containing protein	A7TWG1	Staphylococcus_phage	6.6e-21	100.0
AXI06340.1\|1669311_1669575_-	Phage protein	A0A2K9VBS9	Staphylococcus_phage	5.7e-46	100.0
AXI06341.1\|1669599_1669815_-	Phage protein	A0A2I6PF01	Staphylococcus_phage	1.9e-31	100.0
AXI06342.1\|1669869_1670235_+	Phage protein	A0A2I6PF07	Staphylococcus_phage	2.4e-63	100.0
AXI06343.1\|1670203_1670449_-	Phage protein	A0A2I6PF15	Staphylococcus_phage	5.1e-41	100.0
AXI06344.1\|1670504_1670714_+	Phage protein	W5R9J5	Staphylococcus_phage	1.2e-30	100.0
AXI06345.1\|1670703_1670847_-	Phage protein	W5R8I6	Staphylococcus_phage	2.5e-16	100.0
AXI06346.1\|1670861_1671305_-	hypothetical protein	U5U777	Staphylococcus_phage	2.3e-76	100.0
AXI06347.1\|1671328_1671550_-	DUF739 domain-containing protein	U5U4R4	Staphylococcus_phage	5.8e-36	100.0
AXI06348.1\|1671710_1672481_+	Phage repressor	U5U470	Staphylococcus_phage	6.2e-141	100.0
AXI06349.1\|1672635_1672821_+	hypothetical protein	U5U7D6	Staphylococcus_phage	2.3e-25	100.0
AXI06350.1\|1672890_1673058_+	hypothetical protein	U5U774	Staphylococcus_phage	1.7e-24	100.0
AXI06351.1\|1673197_1673902_+	Pathogenicity island SaPIn2	U5U4R0	Staphylococcus_phage	4.6e-127	100.0
AXI06352.1\|1674112_1675318_+\|integrase	Phage integrase	U5U466	Staphylococcus_phage	1.0e-222	100.0
AXI06353.1\|1675360_1677388_-	hypothetical protein	B5WZK7	Staphylococcus_phage	8.1e-116	99.5
1675405:1675430	attR	NA	NA	NA	NA
AXI06354.1\|1677380_1678250_-	hypothetical protein	NA	NA	NA	NA
AXI06355.1\|1678550_1680245_-	Osmosensitive K+ channel histidine kinase KdpD	A0A1V0SGX0	Hokovirus	2.2e-21	33.2
AXI06356.1\|1680282_1681008_-	respiratory response protein SrrA	W8CYM9	Bacillus_phage	3.5e-45	43.0

DBSCAN-SWA_8

1815965 : 1825008

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXI06497.1\|1815965_1816484_-	Adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
AXI06498.1\|1816505_1818779_-	Single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	8.1e-64	29.3
AXI06499.1\|1818981_1821261_-	Protein-export membrane protein SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
AXI06500.1\|1821535_1821796_-	Preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
AXI06501.1\|1821814_1822954_-\|tRNA	tRNA-guanine transglycosylase	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
AXI06502.1\|1822976_1824002_-\|tRNA	S-adenosylmethionine:tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
AXI06503.1\|1824003_1825008_-	Holliday junction DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_9

1960304 : 2018875

Staphylococcus_phage(92.0%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXI06617.1\|1960304_1963229_-	putative cell-wall-anchored protein SasC (LPXTG motif)	A0A2H4PQU6	Staphylococcus_phage	2.6e-163	99.2
AXI06618.1\|1963554_1963866_-	Rhodanese-like domain protein	A0A2H4PQR9	Staphylococcus_phage	4.8e-52	99.0
AXI06619.1\|1963887_1966305_-\|tRNA	Leucyl-tRNA synthetase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.5
AXI06620.1\|1966592_1967774_-	Multidrug resistance protein B	A0A2H4PQR6	Staphylococcus_phage	7.3e-218	99.7
AXI06621.1\|1967883_1968837_+	putative Fe-S oxidoreductase	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
AXI06622.1\|1968833_1969397_+	SAM-dependent methyltransferase, MraW methylase family	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
AXI06623.1\|1969519_1969921_-	Repressor of toxins Rot	NA	NA	NA	NA
AXI06624.1\|1970490_1971318_-	alpha/beta hydrolase	NA	NA	NA	NA
AXI06625.1\|1971551_1972553_+	Proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	2.6e-184	99.4
AXI06626.1\|1972674_1973139_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.5e-70	100.0
AXI06627.1\|1973151_1974333_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	5.6e-226	99.5
AXI06628.1\|1974343_1974976_-	Riboflavin synthase eubacterial/eukaryotic	A0A2H4PQS5	Staphylococcus_phage	5.5e-111	98.6
AXI06629.1\|1974982_1976026_-	riboflavin biosynthesis protein RibD	A0A2H4PQS8	Staphylococcus_phage	4.5e-195	98.5
AXI06630.1\|1976506_1978009_-	pyridine nucleotide-disulfide oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
AXI06631.1\|1978531_1978846_+	Bacterial regulatory protein, arsR family	A0A2H4PQT4	Staphylococcus_phage	9.8e-53	98.1
AXI06632.1\|1978845_1980138_+	Arsenic efflux pump protein	A0A2H4PQU3	Staphylococcus_phage	4.2e-227	99.1
AXI06633.1\|1980224_1981079_-	Autolysin	Q4ZCC7	Staphylococcus_virus	1.3e-38	38.6
AXI06634.1\|1981354_1981579_-	hypothetical protein	NA	NA	NA	NA
AXI06635.1\|1981699_1982248_+	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	9.3e-83	98.7
AXI06636.1\|1982660_1982804_+	ComK-like	NA	NA	NA	NA
AXI06637.1\|1982790_1983234_-	Hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
AXI06638.1\|1983529_1984165_+\|protease	CAAX amino terminal protease family	NA	NA	NA	NA
AXI06639.1\|1984604_1985318_-	Transaldolase	M1PR54	Cyanophage	9.4e-19	35.3
AXI06640.1\|1985577_1985880_+	Hypothetical protein	NA	NA	NA	NA
AXI06641.1\|1986135_1986501_+	CrcB protein	A0A2H4PQR0	Staphylococcus_phage	1.4e-58	99.2
AXI06642.1\|1986497_1986851_+	CrcB protein	A0A2H4PQQ7	Staphylococcus_phage	3.8e-21	94.0
AXI06643.1\|1987498_1987663_+	Mobile element protein	A0A146ICT8	Staphylococcus_phage	2.9e-24	98.1
AXI06644.1\|1988176_1988785_+	Transposase DDE domain	A0ZS58	Staphylococcus_virus	1.3e-109	96.5
AXI06645.1\|1988847_1989681_-	oxidoreductase of aldo/keto reductase family, subgroup 1	A0A2H4PQR8	Staphylococcus_phage	7.8e-158	99.3
AXI06646.1\|1989892_1990801_-	Hypothetical protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
AXI06647.1\|1990922_1992119_-	S-adenosylmethionine synthetase	A0A2H4PQS6	Staphylococcus_phage	4.3e-218	99.5
AXI06648.1\|1992490_1994083_+	Phosphoenolpyruvate carboxykinase	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
AXI06649.1\|1994460_1995231_-	Dipeptidyl aminopeptidase/acylaminoacyl-peptidase	A0A2H4PQM6	Staphylococcus_phage	1.5e-142	98.8
AXI06650.1\|1995211_1995691_-	8-oxo-dGTPase Bsu YtkD / 8-oxo-GTPase Bsu YtkD	A0A2H4PQM4	Staphylococcus_phage	3.0e-85	99.4
AXI06651.1\|1995750_1996008_+	Protein YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
AXI06652.1\|1996004_1997006_-	O-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	5.3e-185	97.3
AXI06653.1\|1997010_1998489_-	O-succinylbenzoic acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.8e-283	97.6
AXI06654.1\|1998647_1999088_-	lipoprotein	A0A2H4PQN7	Staphylococcus_phage	2.6e-80	99.3
AXI06655.1\|1999441_2000056_+	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	1.1e-42	93.1
AXI06656.1\|2000136_2001132_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	2.6e-67	97.9
AXI06657.1\|2001206_2001833_+	Hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	3.1e-74	79.8
AXI06658.1\|2001873_2002215_+	DUF3969 domain-containing protein	A0A2H4PQN6	Staphylococcus_phage	1.1e-54	94.7
AXI06659.1\|2002315_2002888_+	Hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	2.3e-23	93.1
AXI06660.1\|2003085_2003655_-	Integrase core domain	A0A2I7SC85	Paenibacillus_phage	1.3e-55	56.8
AXI06661.1\|2003676_2003886_-	Mobile element protein	A0A2H4PQV6	Staphylococcus_phage	4.7e-27	91.2
AXI06662.1\|2004685_2005096_-\|transposase	IS21 family transposase	NA	NA	NA	NA
AXI06663.1\|2005637_2006867_-	Type I restriction-modification system, specificity subunit S	A0A2H4PQP5	Staphylococcus_phage	6.8e-134	64.7
AXI06664.1\|2006859_2008416_-	Type I restriction-modification system, DNA-methyltransferase subunit M	A0A2H4PQP4	Staphylococcus_phage	1.6e-289	100.0
AXI06665.1\|2008776_2009496_-\|protease	serine protease	A0A2H4PQP1	Staphylococcus_phage	1.9e-131	99.6
AXI06666.1\|2009653_2010373_-\|protease	serine protease	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
AXI06667.1\|2010493_2011213_-\|protease	serine protease	A0A2H4PQP7	Staphylococcus_phage	1.3e-129	98.7
AXI06668.1\|2011270_2011993_-\|protease	serine protease	A0A2H4PQN0	Staphylococcus_phage	3.5e-130	98.3
AXI06669.1\|2012117_2012825_-\|protease	serine protease	A0A2H4PQN3	Staphylococcus_phage	7.9e-127	97.0
AXI06670.1\|2013787_2014369_+	putative beta-lactamase	A0A2H4PQH6	Staphylococcus_phage	9.6e-54	64.8
AXI06671.1\|2014841_2015060_-	BsaG protein	A0A2H4PQH0	Staphylococcus_phage	2.0e-25	80.6
AXI06672.1\|2015315_2015789_+	hypothetical protein	NA	NA	NA	NA
AXI06673.1\|2015793_2016585_+	hypothetical protein	NA	NA	NA	NA
AXI06674.1\|2016954_2017938_-	Leukotoxin LukD	A0A2H4PQH7	Staphylococcus_phage	5.2e-185	99.1
AXI06675.1\|2017939_2018875_-	Leukotoxin LukE	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0

DBSCAN-SWA_10

2025076 : 2029323

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXI06681.1\|2025076_2025832_-	Enterotoxin, phage associated	A0A075M4C7	Staphylococcus_phage	6.0e-40	41.4
AXI06682.1\|2025870_2026266_-	Enterotoxin, phage associated	A0A097PAT7	Streptococcus_pyogenes_phage	1.5e-26	50.4
AXI06683.1\|2026240_2026642_-	Enterotoxin, phage associated	A0A097PAT7	Streptococcus_pyogenes_phage	1.5e-10	37.9
AXI06684.1\|2026795_2027524_-	Superantigen enterotoxin SEK	A0A1X9H080	Staphylococcus_phage	1.1e-27	39.2
AXI06685.1\|2027558_2028278_-	Superantigen enterotoxin SEK	A0A1X9H080	Staphylococcus_phage	2.3e-25	35.8
AXI06686.1\|2028558_2029323_-	Enterotoxin, phage associated	A0A075M4C7	Staphylococcus_phage	3.2e-33	36.9

DBSCAN-SWA_11

2160606 : 2177405

Staphylococcus_phage(68.42%)

terminase,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXI06800.1\|2160606_2161329_+	Superantigen enterotoxin SEL	A0A1X9H080	Staphylococcus_phage	2.1e-26	34.9
AXI06801.1\|2161497_2162298_-	Superantigen enterotoxin SEB	A0A097PAT7	Streptococcus_pyogenes_phage	6.1e-51	47.5
AXI06802.1\|2163084_2163645_+	Secreted protein Ear, superantigen-encoding pathogenicity islands SaPI	Q4ZBG8	Staphylococcus_virus	5.4e-62	68.1
AXI06803.1\|2164523_2165228_+	Toxic shock syndrome toxin 1 (TSST-1)	NA	NA	NA	NA
AXI06804.1\|2165382_2165952_-\|terminase	Putative terminase, superantigen-encoding pathogenicity islands SaPI	Q4ZE85	Staphylococcus_phage	7.9e-101	97.4
AXI06805.1\|2165948_2166290_-	pathogenicity island protein	A0A1W6JQM3	Staphylococcus_phage	1.4e-57	99.1
AXI06806.1\|2166292_2166820_-\|coat	Spore coat protein	A0A1W6JQH7	Staphylococcus_phage	3.5e-87	97.1
AXI06807.1\|2166870_2167089_-	Hypothetical protein	NA	NA	NA	NA
AXI06808.1\|2167106_2167685_-	Hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	4.8e-29	38.9
AXI06809.1\|2167696_2168038_-	pathogenicity island protein	Q4ZE66	Staphylococcus_phage	1.4e-57	99.1
AXI06810.1\|2168487_2169129_-	pathogenicity island protein	Q4ZE67	Staphylococcus_phage	7.2e-111	93.0
AXI06811.1\|2169125_2169506_-	pathogenicity island protein	Q4ZE71	Staphylococcus_phage	1.7e-67	96.8
AXI06812.1\|2169815_2171525_-	Putative DNA helicase, superantigen-encoding pathogenicity islands SaPI	Q4ZE73	Staphylococcus_phage	1.4e-302	92.8
AXI06813.1\|2171538_2172408_-	mobile element-associated protein	Q4ZE74	Staphylococcus_phage	1.5e-164	96.2
AXI06814.1\|2172472_2172799_-	DUF1474 domain-containing protein	Q4ZE75	Staphylococcus_phage	1.5e-48	89.8
AXI06815.1\|2172801_2173011_-	Hypothetical protein	Q4ZE76	Staphylococcus_phage	2.9e-29	94.2
AXI06816.1\|2173003_2173150_-	Hypothetical protein	NA	NA	NA	NA
AXI06817.1\|2173146_2173464_-	excisionase	A0A1W6JQE0	Staphylococcus_phage	9.2e-51	98.1
AXI06818.1\|2173468_2173687_-	XRE family transcriptional regulator	A0A2H4JB11	uncultured_Caudovirales_phage	1.3e-19	66.7
AXI06819.1\|2173859_2174534_+	XRE family transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	1.6e-39	45.8
AXI06820.1\|2174547_2175720_+	Integrase, superantigen-encoding pathogenicity islands SaPI	A0A1W6JQD3	Staphylococcus_phage	5.8e-215	96.2
AXI06821.1\|2175788_2177405_-	Heat shock protein 60 family chaperone GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7

Anti-CRISPR protein detection

Acr_ID: CP022582.1|AXI05885.1|1177304_1177553_+|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

CP022582.1|AXI05885.1|1177304_1177553_+|hypothetical-protein

1177304_1177553_+

82 aa aa

1160401-1243354

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
CP022582_9	Orphan	9.1\|2158084\|34\|CP022582\|CRISPRCasFinder	2158084-2158117	34	1240068-1240035	0

1. spacer 9.1|2158084|34|CP022582|CRISPRCasFinder matches to CP022582 position: 1240068-1240035, mismatch: 0

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctctgtgttgg	Protospacer
**********************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP022582

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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