CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP022900	Staphylococcus aureus strain 468 chromosome, complete genome	10 crisprs	csa3,cas3,DEDDh,DinG,WYL	5	0	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP022900_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022900_1

806580-806664

Unclear

Consensus_repeat	Method
CACCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of CP022900_1

>merge|CP022900|1|806580-806664|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCACACCCCAACTTGCATTGCCTGTAGAA

>CP022900|1|1|806580-806664|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCA
CACCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP022900.1\|AXJ53156.1\|794072_794834_-\|Inner-membrane-protein-YjjP	unknown	unknown	gnl\|CDD\|225514
CP022900.1\|AXJ53171.1\|814787_815720_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
CP022900.1\|AXJ53165.1\|805411_806404_+\|Peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
CP022900.1\|AXJ53168.1\|808832_809069_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227234
CP022900.1\|AXJ53173.1\|816575_817061_+\|Maltose-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100053
CP022900.1\|AXJ53164.1\|802447_804979_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
CP022900.1\|AXJ53163.1\|801461_802034_+\|Putative-sigma-54-modulation-protein	unknown	unknown	gnl\|CDD\|224461
CP022900.1\|AXJ53160.1\|798421_799288_+\|DegV-domain-containing-protein	unknown	unknown	gnl\|CDD\|273257
CP022900.1\|AXJ53167.1\|808185_808836_+\|5'-deoxynucleotidase-YfbR	unknown	unknown	gnl\|CDD\|378993
CP022900.1\|AXJ53174.1\|817068_818508_+\|Tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
CP022900.1\|AXJ53158.1\|796417_797473_+\|putative-undecaprenyl-phosphate-N-acetylglucosaminyl-1-phosphate-transferase	unknown	unknown	gnl\|CDD\|133463
CP022900.1\|AXJ53157.1\|795029_796100_-\|Diguanylate-cyclase-DosC	unknown	unknown	gnl\|CDD\|143635
CP022900.1\|AXJ53159.1\|797636_798278_-\|IMPACT-family-member-YigZ	unknown	unknown	gnl\|CDD\|224653
CP022900.1\|AXJ53169.1\|809337_811323_+\|UvrABC-system-protein-B	unknown	unknown	gnl\|CDD\|235395
CP022900.1\|AXJ53161.1\|799651_800734_+\|UvrABC-system-protein-B	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|226583
CP022900.1\|AXJ53170.1\|811330_814177_+\|UvrABC-system-protein-A	unknown	unknown	gnl\|CDD\|234734
CP022900.1\|AXJ53172.1\|815725_816568_+\|Prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
CP022900.1\|AXJ53162.1\|800726_801401_+\|DNA-utilization-protein-GntX	unknown	unknown	gnl\|CDD\|223970
CP022900.1\|AXJ53166.1\|807172_808012_+\|Secretory-antigen-SsaA-precursor	unknown	unknown	gnl\|CDD\|226451
CP022900.1\|AXJ53175.1\|818574_819510_+\|Thioredoxin-reductase	unknown	unknown	gnl\|CDD\|273540

Protein	Function_ID	Function_description	E-value
CP022900.1\|AXJ53156.1\|794072_794834_-\|Inner-membrane-protein-YjjP	gnl\|CDD\|225514	COG2966, COG2966, Uncharacterized conserved protein [Function unknown].	1.53065e-80
CP022900.1\|AXJ53171.1\|814787_815720_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
CP022900.1\|AXJ53165.1\|805411_806404_+\|Peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
CP022900.1\|AXJ53168.1\|808832_809069_+\|hypothetical-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
CP022900.1\|AXJ53173.1\|816575_817061_+\|Maltose-O-acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	7.57447e-30
CP022900.1\|AXJ53164.1\|802447_804979_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
CP022900.1\|AXJ53163.1\|801461_802034_+\|Putative-sigma-54-modulation-protein	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
CP022900.1\|AXJ53160.1\|798421_799288_+\|DegV-domain-containing-protein	gnl\|CDD\|273257	TIGR00762, DegV, EDD domain protein, DegV family. This family of proteins is related to DegV of Bacillus subtilis and includes paralogous sets in several species (B. subtilis, Deinococcus radiodurans, Mycoplasma pneumoniae) that are closer in percent identity to each than to most homologs from other species. This suggests both recent paralogy and diversity of function. DegV itself is encoded immediately downstream of DegU, a transcriptional regulator of degradation, but is itself uncharacterized. Crystallography suggested a lipid-binding site, while comparison of the crystal structure to dihydroxyacetone kinase and to a mannose transporter EIIA domain suggests a conserved domain, EDD, with phosphotransferase activity. [Unknown function, General].	9.17692e-120
CP022900.1\|AXJ53167.1\|808185_808836_+\|5'-deoxynucleotidase-YfbR	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
CP022900.1\|AXJ53174.1\|817068_818508_+\|Tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	7.77476e-06
CP022900.1\|AXJ53158.1\|796417_797473_+\|putative-undecaprenyl-phosphate-N-acetylglucosaminyl-1-phosphate-transferase	gnl\|CDD\|133463	cd06853, GT_WecA_like, This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate molecule and N-acetylglucosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylglucosamine precursor. WecA participates in the biosynthesis of O antigen LPS in many enteric bacteria and is also involved in the biosynthesis of enterobacterial common antigen. A conserved short sequence motif and a conserved arginine at a cytosolic loop of this integral membrane protein were shown to be critical in recognition of substrate UDP-N-acetylglucosamine.	2.69988e-87
CP022900.1\|AXJ53157.1\|795029_796100_-\|Diguanylate-cyclase-DosC	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.2404e-45
CP022900.1\|AXJ53159.1\|797636_798278_-\|IMPACT-family-member-YigZ	gnl\|CDD\|224653	COG1739, COG1739, Uncharacterized conserved protein [Function unknown].	7.46066e-72
CP022900.1\|AXJ53169.1\|809337_811323_+\|UvrABC-system-protein-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP022900.1\|AXJ53161.1\|799651_800734_+\|UvrABC-system-protein-B	gnl\|CDD\|226583	COG4098, comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair].	1.30855e-179
CP022900.1\|AXJ53170.1\|811330_814177_+\|UvrABC-system-protein-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP022900.1\|AXJ53172.1\|815725_816568_+\|Prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	6.12313e-120
CP022900.1\|AXJ53162.1\|800726_801401_+\|DNA-utilization-protein-GntX	gnl\|CDD\|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	1.20522e-50
CP022900.1\|AXJ53166.1\|807172_808012_+\|Secretory-antigen-SsaA-precursor	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	3.29354e-42
CP022900.1\|AXJ53175.1\|818574_819510_+\|Thioredoxin-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	5.52692e-153

>CP022900.1|AXJ53165.1|805411_806404_+|Peptide-chain-release-factor-2
MAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDGEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVKTVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>CP022900.1|AXJ53164.1|802447_804979_+|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKSVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>CP022900.1|AXJ53163.1|801461_802034_+|Putative-sigma-54-modulation-protein
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>CP022900.1|AXJ53162.1|800726_801401_+|DNA-utilization-protein-GntX
MNNCLSCGAKLYENITIYNLFKKPNRLCDRCKENWDNIKLDIKARRCSRCLKYLDQNEAYCLDCKFLSAHFNLMEQLYCQFQYDGLMKEMIHQYKFSKDYYLCELLAHLIEIPQTSYDYIVPIPSSPAHDLSRTFNPVEAVLKAKGIRFDKILKMSNRPKQSHLTKKERLADENPFIIDTELDLNGKEILLVDDIYTTGLTIHRAGCKLYAKNIRKFKVFAFAR
>CP022900.1|AXJ53161.1|799651_800734_+|UvrABC-system-protein-B
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRMRQTILLYAVTGAGKTEMMFQGIQYARRQGDNIAIVSPRVDVVVEISKRIKDAFLNEDIDILHQQSSQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKSLQQALKSSSKVEHATIYMTATPPKQLLSEIPLENIIKLPARFHKKSLPVPKYRYFKLNNNKIQKMLYRILQDQINNQRYTLVFFNNIETMIKTFSIYKQKITKLTYVHSEDVFRFEKVEQLRNGQYDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKLECPTGKVLFFHEGVSMNMIQAKKEIQKMNKLALKRGWIDE
>CP022900.1|AXJ53160.1|798421_799288_+|DegV-domain-containing-protein
MKIAVMTDSTSYLSQDLIDKYNIQIAPLSVTFDDGKNFTESNEIAIEEFYNKMASSQTIPTTSQPAIGEWITKYEMLRDQGYTDIIVICLSSGISGSYQSSYQAGEMVEGVNVHAFDSKLAAMIEGCYVLRAIEMVEEGYEPQQIIDDLTNMREHTGAYLIVDDLKNLQKSGRITGAQAWVGTLLKMKPVLKFEDGKIIPEEKVRTKKRAIQTLEKKVLDIVKDFEEVTLFVINGDHFEDGQALYKKLQDDCPSAYQVAYSEFGPVVAAHLGSGGLGLGYVGRKIRLT
>CP022900.1|AXJ53159.1|797636_798278_-|IMPACT-family-member-YigZ
MTQNIITVKKEHIIENVISKSRFIAHIKPVQNEDEAKAFIAAIKKEHKDATHNCSAYTIGPEMNIQKANDDGEPTGTAGVPMLDILKKLDVHNACVVVTRYFGGIKLGGGGLIRAYSGAVRDVIYDIGRVELREAVPCIVTLNYDQTGKFEYELASTHFMLRNQTYTDKVSYYIDVVKSDYEAFINFLNQMTAGNFDLTEETPKQLPFDIPTE
>CP022900.1|AXJ53158.1|796417_797473_+|putative-undecaprenyl-phosphate-N-acetylglucosaminyl-1-phosphate-transferase
MVTLLLVAVTMIVSLTITPIVIAISKRLNLVDKPNFRKVHTKPISVMGGTVILFSFLIGIWIGHPIETEIKPLIIGAIIMYVLGLVDDIYDLKPYIKLAGQIAAALVVAFYGVTIDFISLPMGTTIHFGFLSIPITVIWIVAITNAINLIDGLDGLASGVSAIGLITIGFIAILQANIFITMICCVLLGSLIGFLFYNFHPAKIFLGDSGALMIGFIIGFLSLLGFKNITIIALFFPIVILAVPFIDTLFAMIRRVKKGQHIMQADKSHLHHKLLALGYTHRQTVLLIYSISILFSLSSIILYVSPPLGVVLMFVLIIFSIELIVEFTGLIDNNYRPILNLISRKSSHKEE
>CP022900.1|AXJ53157.1|795029_796100_-|Diguanylate-cyclase-DosC
MFEAFIYNISVIVAGIYLFHRLQYSENKRMVFSKAYVTVLMTIVSLLLSVYPIPYREDYLIHLTFVPLLFLGRFTNMVYTLSATVIVAIVEIVVFNNSIMYGVTLIVIAAVTSAIGPFLKQNDVLSLLILNVVTIIILFGVALVSPIYTLSEVIILIPISLIITLASAITFVDIWHFFSLVNRYENEDKYDYLTGLGNVKEFDRHLNEISRKAEKEHQSIALLLIDIDGFKDVNDTYSHKSGDAVLKQMSQLLKNYVPNQFKIFRNGGEEFSVVIHNYSLDQSVKLAENIRSGVEKSSFHLPNKEVIKLSVSIGVGYLTDDDPKSQRKVFKDADDMVHVAKNQGRNKVMFNPIINL
>CP022900.1|AXJ53156.1|794072_794834_-|Inner-membrane-protein-YjjP
MPDSITIIDENKVIDVVLIAGRILLESGAETYRVEDTMNRIAHSYGLHNTYSFVSSTAIIFSLNDRTSTRLIRVQERTTDLEKIALTNSLSRKISNKELTIDEAKSEFIHLQHASLQYSFLTNFFAAAIACGFFLFMFGGVASDCWIAVIAGGSAFLTFSFVQRYIQIKFFSEFVAAAVVISIAATFTKLGIATNQDIITIASVMPLVPGILITNAIRDLLAGELLAGMSRGVEAALTAFAIGAGVAIVLLII
>CP022900.1|AXJ53166.1|807172_808012_+|Secretory-antigen-SsaA-precursor
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKTVKSPVRKASQAKKVVQQPVQQASKKVVVKQAPKQTVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>CP022900.1|AXJ53167.1|808185_808836_+|5'-deoxynucleotidase-YfbR
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>CP022900.1|AXJ53168.1|808832_809069_+|hypothetical-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>CP022900.1|AXJ53169.1|809337_811323_+|UvrABC-system-protein-B
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>CP022900.1|AXJ53170.1|811330_814177_+|UvrABC-system-protein-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNINLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>CP022900.1|AXJ53171.1|814787_815720_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>CP022900.1|AXJ53172.1|815725_816568_+|Prolipoprotein-diacylglyceryl-transferase
MGGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPGEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTRKVK
>CP022900.1|AXJ53173.1|816575_817061_+|Maltose-O-acetyltransferase
MRKFLSKEYHRTNPLWHVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQILNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP022900.1|AXJ53174.1|817068_818508_+|Tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMANQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLKEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP022900.1|AXJ53175.1|818574_819510_+|Thioredoxin-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSAPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP022900_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022900_2

864984-865063

Orphan

Consensus_repeat	Method
CCGTCAGCTTCTGTGTTGGGGCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022900_2

>merge|CP022900|2|864984-865063|CRISPRCasFinder
CCGTCAGCTTCTGTGTTGGGGCCCACCCCAACTTGCATTGCTTGTAAGCTGACTTTCCGTCAGCTTCTATGTTGGGGCCC

>CP022900|2|2|864984-865063|CRISPRCasFinder
CCGTCAGCTTCTGTGTTGGGGCCC	ACCCCAACTTGCATTGCTTGTAAGCTGACTTT
CCGTCAGCTTCTATGTTGGGGCCC

Protein	Signature genes	Signature genes Name	Protein_function
CP022900.1\|AXJ53225.1\|869612_869807_+\|CsbD-like-protein	unknown	unknown	gnl\|CDD\|225777
CP022900.1\|AXJ53220.1\|865317_865707_+\|Ribonuclease-M5	unknown	unknown	gnl\|CDD\|224572
CP022900.1\|AXJ53212.1\|859364_859859_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372596
CP022900.1\|AXJ53219.1\|863737_864730_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226395
CP022900.1\|AXJ53227.1\|871219_871981_+\|YurY	unknown	unknown	gnl\|CDD\|223473
CP022900.1\|AXJ53223.1\|867263_867959_+\|Methionine-import-system-permease-protein-MetP	unknown	unknown	gnl\|CDD\|224922
CP022900.1\|AXJ53215.1\|861626_862166_+\|putative-oxidoreductase	unknown	unknown	gnl\|CDD\|380312
CP022900.1\|AXJ53229.1\|873500_874742_+\|putative-cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
CP022900.1\|AXJ53218.1\|863293_863674_+\|Glycine-cleavage-system-H-protein	unknown	unknown	gnl\|CDD\|234918
CP022900.1\|AXJ53213.1\|860257_860680_-\|Organic-hydroperoxide-resistance-protein-like-protein	unknown	unknown	gnl\|CDD\|274649
CP022900.1\|AXJ53210.1\|857934_858519_+\|Putative-phosphoserine-phosphatase-2	unknown	unknown	gnl\|CDD\|223483
CP022900.1\|AXJ53226.1\|870040_870892_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224946
CP022900.1\|AXJ53222.1\|866245_867271_+\|Methionine-import-ATP-binding-protein-MetN-2	unknown	unknown	gnl\|CDD\|224058
CP022900.1\|AXJ53217.1\|862779_863136_+\|Regulatory-protein-MgsR	unknown	unknown	gnl\|CDD\|239334
CP022900.1\|AXJ53211.1\|858591_859209_-\|Arginine-exporter-protein-ArgO	unknown	unknown	gnl\|CDD\|224198
CP022900.1\|AXJ53216.1\|862315_862636_-\|Thioredoxin-like-protein-YdbP	unknown	unknown	gnl\|CDD\|239245
CP022900.1\|AXJ53224.1\|867976_868798_+\|Methionine-binding-lipoprotein-MetQ-precursor	unknown	unknown	gnl\|CDD\|224381
CP022900.1\|AXJ53214.1\|860827_861544_+\|3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
CP022900.1\|AXJ53228.1\|872078_873386_+\|FeS-cluster-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|223791
CP022900.1\|AXJ53221.1\|865699_865996_+\|Thioredoxin	unknown	unknown	gnl\|CDD\|239245

Protein	Function_ID	Function_description	E-value
CP022900.1\|AXJ53225.1\|869612_869807_+\|CsbD-like-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
CP022900.1\|AXJ53220.1\|865317_865707_+\|Ribonuclease-M5	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	3.40012e-36
CP022900.1\|AXJ53212.1\|859364_859859_-\|hypothetical-protein	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
CP022900.1\|AXJ53219.1\|863737_864730_+\|hypothetical-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.53309e-76
CP022900.1\|AXJ53227.1\|871219_871981_+\|YurY	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
CP022900.1\|AXJ53223.1\|867263_867959_+\|Methionine-import-system-permease-protein-MetP	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
CP022900.1\|AXJ53215.1\|861626_862166_+\|putative-oxidoreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
CP022900.1\|AXJ53229.1\|873500_874742_+\|putative-cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
CP022900.1\|AXJ53218.1\|863293_863674_+\|Glycine-cleavage-system-H-protein	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	9.01516e-70
CP022900.1\|AXJ53213.1\|860257_860680_-\|Organic-hydroperoxide-resistance-protein-like-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	1.40241e-61
CP022900.1\|AXJ53210.1\|857934_858519_+\|Putative-phosphoserine-phosphatase-2	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	1.10478e-47
CP022900.1\|AXJ53226.1\|870040_870892_-\|hypothetical-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	1.10175e-76
CP022900.1\|AXJ53222.1\|866245_867271_+\|Methionine-import-ATP-binding-protein-MetN-2	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	2.26346e-169
CP022900.1\|AXJ53217.1\|862779_863136_+\|Regulatory-protein-MgsR	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
CP022900.1\|AXJ53211.1\|858591_859209_-\|Arginine-exporter-protein-ArgO	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	5.25608e-61
CP022900.1\|AXJ53216.1\|862315_862636_-\|Thioredoxin-like-protein-YdbP	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	3.63533e-24
CP022900.1\|AXJ53224.1\|867976_868798_+\|Methionine-binding-lipoprotein-MetQ-precursor	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	5.3847e-113
CP022900.1\|AXJ53214.1\|860827_861544_+\|3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	6.29269e-147
CP022900.1\|AXJ53228.1\|872078_873386_+\|FeS-cluster-assembly-protein-SufB	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	8.11734e-136
CP022900.1\|AXJ53221.1\|865699_865996_+\|Thioredoxin	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	1.8621e-13

>CP022900.1|AXJ53219.1|863737_864730_+|hypothetical-protein
MKENLLGTIIWSIATFYYSRMMKIMNLAILKIKIGGVNMLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLNDLPEQQELFPVNEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLKDIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDDLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>CP022900.1|AXJ53218.1|863293_863674_+|Glycine-cleavage-system-H-protein
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQLEALLTAEKYSEMIGE
>CP022900.1|AXJ53217.1|862779_863136_+|Regulatory-protein-MgsR
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>CP022900.1|AXJ53216.1|862315_862636_-|Thioredoxin-like-protein-YdbP
MQAIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>CP022900.1|AXJ53215.1|861626_862166_+|putative-oxidoreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>CP022900.1|AXJ53214.1|860827_861544_+|3-dehydroquinate-dehydratase
MTHVEVVATITPQLYIEETLIQKINHRIDAIDVLELRIDQFENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVIISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>CP022900.1|AXJ53213.1|860257_860680_-|Organic-hydroperoxide-resistance-protein-like-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDPDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>CP022900.1|AXJ53212.1|859364_859859_-|hypothetical-protein
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>CP022900.1|AXJ53211.1|858591_859209_-|Arginine-exporter-protein-ArgO
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLFIIIAVVGVSIIIMSLPILQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF
>CP022900.1|AXJ53210.1|857934_858519_+|Putative-phosphoserine-phosphatase-2
MLAKTLYLMRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYYETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGLFEGESVYLFDNLYKPEDLFGDRIVPFKGEARQQVEDRIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKLDEALKHNIGNCNILKFEYDNGTFKFVELIDPNL
>CP022900.1|AXJ53220.1|865317_865707_+|Ribonuclease-M5
MMAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSNDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPFLPNINNERLVLVNE
>CP022900.1|AXJ53221.1|865699_865996_+|Thioredoxin
MNNSLDIKDVTTFYEEDKHLIYGYTPTCGTCKVSERMLDITNEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFQSVTDLLENLK
>CP022900.1|AXJ53222.1|866245_867271_+|Methionine-import-ATP-binding-protein-MetN-2
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIILITHEMHVIRRICDEVAVMESGKVIEHGPVTQVFENPQHAVTKRFVKEDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSIDFGKFEKELIERQVKMEVLRHG
>CP022900.1|AXJ53223.1|867263_867959_+|Methionine-import-system-permease-protein-MetP
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>CP022900.1|AXJ53224.1|867976_868798_+|Methionine-binding-lipoprotein-MetQ-precursor
MKKLFGLILVLTFAVVLAACGNGSKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGNVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>CP022900.1|AXJ53225.1|869612_869807_+|CsbD-like-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>CP022900.1|AXJ53226.1|870040_870892_-|hypothetical-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNSDKHAGETLTLSTGLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>CP022900.1|AXJ53227.1|871219_871981_+|YurY
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>CP022900.1|AXJ53228.1|872078_873386_+|FeS-cluster-assembly-protein-SufB
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>CP022900.1|AXJ53229.1|873500_874742_+|putative-cysteine-desulfurase
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLINALKQTKEFFSYEF

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP022900_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022900_3

914104-914189

Orphan

Consensus_repeat	Method
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022900_3

>merge|CP022900|3|914104-914189|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGTGGAAAGCCAGCTTACAATAATGTGCAAGTTGG

>CP022900|3|3|914104-914189|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CGGGGCCCCAACACAGAAGCTGGTGG
AAAGCCAGCTTACAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
CP022900.1\|AXJ53262.1\|902993_904490_-\|Na(+)/H(+)-antiporter-subunit-D1	unknown	unknown	gnl\|CDD\|181085
CP022900.1\|AXJ53277.1\|920680_921205_+\|Signal-peptidase-IB	unknown	unknown	gnl\|CDD\|274044
CP022900.1\|AXJ53278.1\|921220_921796_+\|Signal-peptidase-IB	unknown	unknown	gnl\|CDD\|274044
CP022900.1\|AXJ53265.1\|905244_907650_-\|Na(+)/H(+)-antiporter-subunit-A1	unknown	unknown	gnl\|CDD\|237155
CP022900.1\|AXJ53274.1\|916887_918093_-\|Argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
CP022900.1\|AXJ53263.1\|904482_904824_-\|Na(+)/H(+)-antiporter-subunit-C1	unknown	unknown	gnl\|CDD\|181497
CP022900.1\|AXJ53267.1\|908227_908821_+\|Putative-peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|238908
CP022900.1\|AXJ53281.1\|929251_930154_+\|Ureidoglycolate-lyase	unknown	unknown	gnl\|CDD\|223257
CP022900.1\|AXJ53268.1\|909235_909613_+\|General-stress-protein-13	unknown	unknown	gnl\|CDD\|224023
CP022900.1\|AXJ53280.1\|925432_929086_+\|ATP-dependent-helicase/nuclease-subunit-A	unknown	unknown	gnl\|CDD\|274299
CP022900.1\|AXJ53264.1\|904823_905252_-\|Na(+)/H(+)-antiporter-subunit-B1	unknown	unknown	gnl\|CDD\|183602
CP022900.1\|AXJ53276.1\|920100_920676_+\|TVP38/TMEM64-family-inner-membrane-protein-YdjZ	unknown	unknown	gnl\|CDD\|223475
CP022900.1\|AXJ53279.1\|921955_925432_+\|ATP-dependent-helicase/deoxyribonuclease-subunit-B	unknown	unknown	gnl\|CDD\|213736
CP022900.1\|AXJ53275.1\|918443_919775_+\|Glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
CP022900.1\|AXJ53271.1\|912708_913953_+\|NAD-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
CP022900.1\|AXJ53272.1\|914347_915277_-\|putative-glycerophosphoryl-diester-phosphodiesterase-1	unknown	unknown	gnl\|CDD\|176543
CP022900.1\|AXJ53269.1\|909974_911102_+\|NADH-oxidase	unknown	unknown	gnl\|CDD\|240086
CP022900.1\|AXJ53270.1\|911409_912600_+\|Ornithine-aminotransferase-2	unknown	unknown	gnl\|CDD\|179736
CP022900.1\|AXJ53273.1\|915518_916898_-\|Argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
CP022900.1\|AXJ53266.1\|907780_908164_-\|Kinase-associated-lipoprotein-B-precursor	unknown	unknown	gnl\|CDD\|378054

Protein	Function_ID	Function_description	E-value
CP022900.1\|AXJ53262.1\|902993_904490_-\|Na(+)/H(+)-antiporter-subunit-D1	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
CP022900.1\|AXJ53277.1\|920680_921205_+\|Signal-peptidase-IB	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.75286e-49
CP022900.1\|AXJ53278.1\|921220_921796_+\|Signal-peptidase-IB	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.63465e-53
CP022900.1\|AXJ53265.1\|905244_907650_-\|Na(+)/H(+)-antiporter-subunit-A1	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
CP022900.1\|AXJ53274.1\|916887_918093_-\|Argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
CP022900.1\|AXJ53263.1\|904482_904824_-\|Na(+)/H(+)-antiporter-subunit-C1	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	9.82501e-64
CP022900.1\|AXJ53267.1\|908227_908821_+\|Putative-peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
CP022900.1\|AXJ53281.1\|929251_930154_+\|Ureidoglycolate-lyase	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	6.54658e-87
CP022900.1\|AXJ53268.1\|909235_909613_+\|General-stress-protein-13	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
CP022900.1\|AXJ53280.1\|925432_929086_+\|ATP-dependent-helicase/nuclease-subunit-A	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
CP022900.1\|AXJ53264.1\|904823_905252_-\|Na(+)/H(+)-antiporter-subunit-B1	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
CP022900.1\|AXJ53276.1\|920100_920676_+\|TVP38/TMEM64-family-inner-membrane-protein-YdjZ	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	4.0006e-40
CP022900.1\|AXJ53279.1\|921955_925432_+\|ATP-dependent-helicase/deoxyribonuclease-subunit-B	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
CP022900.1\|AXJ53275.1\|918443_919775_+\|Glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
CP022900.1\|AXJ53271.1\|912708_913953_+\|NAD-specific-glutamate-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
CP022900.1\|AXJ53272.1\|914347_915277_-\|putative-glycerophosphoryl-diester-phosphodiesterase-1	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	8.83368e-151
CP022900.1\|AXJ53269.1\|909974_911102_+\|NADH-oxidase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
CP022900.1\|AXJ53270.1\|911409_912600_+\|Ornithine-aminotransferase-2	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
CP022900.1\|AXJ53273.1\|915518_916898_-\|Argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
CP022900.1\|AXJ53266.1\|907780_908164_-\|Kinase-associated-lipoprotein-B-precursor	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	8.96507e-53

>CP022900.1|AXJ53271.1|912708_913953_+|NAD-specific-glutamate-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>CP022900.1|AXJ53270.1|911409_912600_+|Ornithine-aminotransferase-2
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINKNTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFARDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>CP022900.1|AXJ53269.1|909974_911102_+|NADH-oxidase
MKSKYEPLFDKVVLPNGVELRNRFVLAPLTHISSNDDGTISDIELPYIEKRSQDVGITSNAASNVSDVGKAFPGQPSIAHDSDIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPIAVIEEVLKSKEVYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATAREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADDALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>CP022900.1|AXJ53268.1|909235_909613_+|General-stress-protein-13
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>CP022900.1|AXJ53267.1|908227_908821_+|Putative-peptidyl-prolyl-cis-trans-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>CP022900.1|AXJ53266.1|907780_908164_-|Kinase-associated-lipoprotein-B-precursor
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHERKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>CP022900.1|AXJ53265.1|905244_907650_-|Na(+)/H(+)-antiporter-subunit-A1
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWIWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMTMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASKANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTVFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>CP022900.1|AXJ53264.1|904823_905252_-|Na(+)/H(+)-antiporter-subunit-B1
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>CP022900.1|AXJ53263.1|904482_904824_-|Na(+)/H(+)-antiporter-subunit-C1
MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>CP022900.1|AXJ53262.1|902993_904490_-|Na(+)/H(+)-antiporter-subunit-D1
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPLRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAITRTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK
>CP022900.1|AXJ53272.1|914347_915277_-|putative-glycerophosphoryl-diester-phosphodiesterase-1
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNHIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDENVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNKNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>CP022900.1|AXJ53273.1|915518_916898_-|Argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLSTYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>CP022900.1|AXJ53274.1|916887_918093_-|Argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMRAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>CP022900.1|AXJ53275.1|918443_919775_+|Glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>CP022900.1|AXJ53276.1|920100_920676_+|TVP38/TMEM64-family-inner-membrane-protein-YdjZ
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVDTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLIVFWIVGKKLEQHFMGSKKE
>CP022900.1|AXJ53277.1|920680_921205_+|Signal-peptidase-IB
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKKLDGDIIPPNNFVVLNDHDNNQHDSRQFGLIDKKDIIGNISLRYYPFSKWTIQFKS
>CP022900.1|AXJ53278.1|921220_921796_+|Signal-peptidase-IB
MKKELLEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKYNFNPENTKN
>CP022900.1|AXJ53279.1|921955_925432_+|ATP-dependent-helicase/deoxyribonuclease-subunit-B
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLESFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDALQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEISNELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQINPMLRLLKTDVLTTSYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAATVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGNVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDHLSQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNEDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>CP022900.1|AXJ53280.1|925432_929086_+|ATP-dependent-helicase/nuclease-subunit-A
MTIPEKPQGVIWTDAQWQSIYETGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDISYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFHEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTLDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVRYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVFDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYKAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIIYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADTKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>CP022900.1|AXJ53281.1|929251_930154_+|Ureidoglycolate-lyase
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVERLYVFTKAASSLTGDNAKIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK

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Crispr_ID: CP022900_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022900_4

1215354-1215446

Unclear

Consensus_repeat	Method
TAAGAAACAGTAATCAATAAATTGATAACT	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of CP022900_4

>merge|CP022900|4|1215354-1215446|CRISPRCasFinder
TAAGAAACAGTAATCAATAAATTGATAACTAATAAGCGGAACGCCTGAGCTAAAGCTCATGCATAAGAAACAGTAATCAATAAATTGATAACT

>CP022900|4|4|1215354-1215446|CRISPRCasFinder
TAAGAAACAGTAATCAATAAATTGATAACT	AATAAGCGGAACGCCTGAGCTAAAGCTCATGCA
TAAGAAACAGTAATCAATAAATTGATAACT

Protein	Signature genes	Signature genes Name	Protein_function
CP022900.1\|AXJ53546.1\|1223725_1224001_+\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|223306
CP022900.1\|AXJ53537.1\|1212597_1213584_+\|Phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|235414
CP022900.1\|AXJ53543.1\|1220328_1221579_+\|Signal-recognition-particle-receptor-FtsY	unknown	unknown	gnl\|CDD\|236686
CP022900.1\|AXJ53541.1\|1215884_1216616_+\|Ribonuclease-3	unknown	unknown	gnl\|CDD\|234633
CP022900.1\|AXJ53549.1\|1225531_1225882_+\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
CP022900.1\|AXJ53534.1\|1207921_1209568_+\|DAK2-domain-protein	unknown	unknown	gnl\|CDD\|224378
CP022900.1\|AXJ53536.1\|1212035_1212593_+\|Transcription-factor-FapR	unknown	unknown	gnl\|CDD\|179847
CP022900.1\|AXJ53531.1\|1205879_1206521_+\|Thiamine-pyrophosphokinase	unknown	unknown	gnl\|CDD\|224480
CP022900.1\|AXJ53539.1\|1214495_1215230_+\|3-oxoacyl-[acyl-carrier-protein]-reductase-FabG	unknown	unknown	gnl\|CDD\|235500
CP022900.1\|AXJ53530.1\|1205228_1205873_+\|Ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
CP022900.1\|AXJ53542.1\|1216762_1220329_+\|Chromosome-partition-protein-Smc	unknown	unknown	gnl\|CDD\|224117
CP022900.1\|AXJ53532.1\|1206901_1207090_-\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|234736
CP022900.1\|AXJ53544.1\|1221565_1221898_+\|putative-DNA-binding-protein	unknown	unknown	gnl\|CDD\|234647
CP022900.1\|AXJ53545.1\|1221923_1223291_+\|Signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
CP022900.1\|AXJ53540.1\|1215535_1215769_+\|Acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
CP022900.1\|AXJ53535.1\|1209757_1211818_+\|ATP-dependent-DNA-helicase-RecG	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|236794
CP022900.1\|AXJ53533.1\|1207532_1207907_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224221
CP022900.1\|AXJ53547.1\|1224188_1224692_+\|Ribosome-maturation-factor-RimM	unknown	unknown	gnl\|CDD\|234650
CP022900.1\|AXJ53548.1\|1224691_1225429_+\|tRNA-(guanine-N(1)-)-methyltransferase	unknown	unknown	gnl\|CDD\|234581
CP022900.1\|AXJ53538.1\|1213576_1214503_+\|Malonyl-CoA-acyl-carrier-protein-transacylase	unknown	unknown	gnl\|CDD\|223408

Protein	Function_ID	Function_description	E-value
CP022900.1\|AXJ53546.1\|1223725_1224001_+\|30S-ribosomal-protein-S16	gnl\|CDD\|223306	COG0228, RpsP, Ribosomal protein S16 [Translation, ribosomal structure and biogenesis].	3.01687e-41
CP022900.1\|AXJ53537.1\|1212597_1213584_+\|Phosphate-acyltransferase	gnl\|CDD\|235414	PRK05331, PRK05331, phosphate acyltransferase PlsX.	7.80762e-178
CP022900.1\|AXJ53543.1\|1220328_1221579_+\|Signal-recognition-particle-receptor-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	0
CP022900.1\|AXJ53541.1\|1215884_1216616_+\|Ribonuclease-3	gnl\|CDD\|234633	PRK00102, rnc, ribonuclease III; Reviewed.	4.78039e-115
CP022900.1\|AXJ53549.1\|1225531_1225882_+\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	6.77895e-70
CP022900.1\|AXJ53534.1\|1207921_1209568_+\|DAK2-domain-protein	gnl\|CDD\|224378	COG1461, COG1461, Predicted kinase related to dihydroxyacetone kinase [General function prediction only].	0
CP022900.1\|AXJ53536.1\|1212035_1212593_+\|Transcription-factor-FapR	gnl\|CDD\|179847	PRK04424, PRK04424, transcription factor FapR.	2.33658e-99
CP022900.1\|AXJ53531.1\|1205879_1206521_+\|Thiamine-pyrophosphokinase	gnl\|CDD\|224480	COG1564, THI80, Thiamine pyrophosphokinase [Coenzyme metabolism].	1.16343e-81
CP022900.1\|AXJ53539.1\|1214495_1215230_+\|3-oxoacyl-[acyl-carrier-protein]-reductase-FabG	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	3.68137e-140
CP022900.1\|AXJ53530.1\|1205228_1205873_+\|Ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	9.86946e-113
CP022900.1\|AXJ53542.1\|1216762_1220329_+\|Chromosome-partition-protein-Smc	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0
CP022900.1\|AXJ53532.1\|1206901_1207090_-\|50S-ribosomal-protein-L28	gnl\|CDD\|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	1.3072e-18
CP022900.1\|AXJ53544.1\|1221565_1221898_+\|putative-DNA-binding-protein	gnl\|CDD\|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	1.00966e-46
CP022900.1\|AXJ53545.1\|1221923_1223291_+\|Signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
CP022900.1\|AXJ53540.1\|1215535_1215769_+\|Acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	5.23888e-31
CP022900.1\|AXJ53535.1\|1209757_1211818_+\|ATP-dependent-DNA-helicase-RecG	gnl\|CDD\|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
CP022900.1\|AXJ53533.1\|1207532_1207907_+\|hypothetical-protein	gnl\|CDD\|224221	COG1302, COG1302, Uncharacterized protein conserved in bacteria [Function unknown].	4.1554e-37
CP022900.1\|AXJ53547.1\|1224188_1224692_+\|Ribosome-maturation-factor-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	1.02289e-68
CP022900.1\|AXJ53548.1\|1224691_1225429_+\|tRNA-(guanine-N(1)-)-methyltransferase	gnl\|CDD\|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	3.27017e-164
CP022900.1\|AXJ53538.1\|1213576_1214503_+\|Malonyl-CoA-acyl-carrier-protein-transacylase	gnl\|CDD\|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	6.35101e-134

>CP022900.1|AXJ53539.1|1214495_1215230_+|3-oxoacyl-[acyl-carrier-protein]-reductase-FabG
MTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
>CP022900.1|AXJ53538.1|1213576_1214503_+|Malonyl-CoA-acyl-carrier-protein-transacylase
MSKTAIIFPGQGAQKVGMAQDLYNNNDQATEILTSAANTLDFDILETMFTDEEGKLGETENTQPALLTHSSALLAALKNLNPDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQAFPSGVGSMAAVLGLDFDKVDEICKSLSSDDKIIEPANINCPGQIVVSGHKALIDELVEKGKSLGAKRVMPLAVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEVIKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLEDVKGWNEND
>CP022900.1|AXJ53537.1|1212597_1213584_+|Phosphate-acyltransferase
MVKLAIDMMGGDNAPDIVLEAVQKAVEDFKDLEIILFGDEKKYNLNHERIEFRHCSEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALMSAGLFIVGRIKGVARPALVVTLPTIDGKGFVFLDVGANADAKPEHLLQYAQLGDIYAQKIRGIDNPKISLLNIGTEPAKGNSLTKKSYELLNQDHSLNFVGNIEAKTLMDGDTDVVVTDGYTGNMVLKNLEGTAKSIGKMLKDTIMSSTKNKIAGAILKKDLAEFAKKMDYSEYGGSVLLGLEGTVVKAHGSSNAKAFYSAIRQAKIAGEQNIVQTMKETVGESNE
>CP022900.1|AXJ53536.1|1212035_1212593_+|Transcription-factor-FapR
MKLKKDKRREAIRQQIDSNPFITDHELSDLFQVSIQTIRLDRTYLNIPELRKRIKLVAEKNYDQISSIEEQEFIGDLIQVNPNVKAQSILDITSDSVFHKTGIARGHVLFAQANSLCVALIKQPTVLTHESSIQFIEKVKLNDTVRAEARVVNQTAKHYYVEVKSYVKHTLVFKGNFKMFYDKRG
>CP022900.1|AXJ53535.1|1209757_1211818_+|ATP-dependent-DNA-helicase-RecG
MAKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPTRYEDNTVIDLNQAEDQSNVTIEGQVYTAPVVAFFGRNKSKLTVHLMVNNIAVKCIFFNQPYLKKKIELNQTITVKGKWNRVKQEITGNRVFLNSQGTQTQENADVQLEPVYRIKEGIKQKQIRDQIRQALNDVTIHEWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRTYAFTELFLFELRMQWLNRLEKSSDEAIEIDYDLDQVKSFIDRLPFELTEAQKSSVNEIFRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMVPTEILAEQHAESLIALFGDSMNVALLTGSVKGKKRKILLEQLENRTIDCLIGTHALIQDDVIFHNVGLVITDEQHRFGVNQRQLLREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPIITTWAKHEQYDKVLMQMTSELKKGRQAYVICPLIESSEHLEDVQNVVALYESLQQYYGVSRVGLLHGKLSADEKDEVMQKFSNHEIDVLVSTTVVEVGVNVPNATFMMIYDADRFGLSTLHQLRGRVGRSDQQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVANLVEDYRMLEVARDEAAELIQSGVFFENTYQHLRHFVEENLLHRSFD
>CP022900.1|AXJ53534.1|1207921_1209568_+|DAK2-domain-protein
MISKINGKLFADMIIQGAQNLSNNADLVDSLNVYPVPDGDTGTNMNLTMTSGREEVENNLSKNIGELGKTFSKGLLMGARGNSGVILSQLFRGFCKNIESESEINSKLLAESFQAGVETAYKAVMKPVEGTILTVAKDAAQAAIEKANNTEDCIELMEYIIVKANESLENTPNLLAVLKEVGVVDSGGKGLLCVYEGFLKALKGEKVEAKVAKLDKDEFVHDEHDFHGVINTEDIIYGYCTEMMVRFGKNKKAFDEQEFRQDMSQFGDSLLVINDEEIVKVHVHTEYPGKVFNYGQQYGELIKLKVENMREQHREVIRKEQHTAKPKMETVETAIITISMGEGISEIFKSMGATHIISGGQTMNPSTEDIVKVIEQSKCKRAIILPNNKNILMASEQAASIVDAEAVVIPTKSIPQGISALFQYDVDATLEENKAQMADSVNNVKSGSLTYAVRDTKIDGVEIKKDAFMGLIEDKIVSSQSDQLTTVTELLNEMLADDSEILTVIIGQDAEQAVTDNMINWIEEQYPDVEVEVHEGGQPIYQYFFSVE
>CP022900.1|AXJ53533.1|1207532_1207907_+|hypothetical-protein
MTLEISNDYGKIDISNEVIASVVGGKAVECYGIVGMASRQQVRDGIAEILGHENYAKGIKVTENNGVVDIDMYIIVSYGVKISEVANNVQSTVKYTLEKSLNVSVNSINIYVQGVRVNNTGKKA
>CP022900.1|AXJ53532.1|1206901_1207090_-|50S-ribosomal-protein-L28
MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
>CP022900.1|AXJ53531.1|1205879_1206521_+|Thiamine-pyrophosphokinase
MHINLLCSDRHLPQDIWAKSNEGKWGGVDRGALILLKHQIIPFFSVGDFDSVSKEERQLLTEQLQIKPVQAEKADTDLALAVDKAVALGFDSITIYGATGGRLDHFFGAIQLLLKKAYYKHDVHIEVIDQQNKIELLPKGQHTVEKDKSYPYISFIPMTDDVELSLAGFKYNLARQMLNIGSTLTISNEIESLQAKVTVHDGLILQIRSTDLN
>CP022900.1|AXJ53530.1|1205228_1205873_+|Ribulose-phosphate-3-epimerase
MTKLYPSLLSVDFLDLQHELKRLEEAGVDGVHFDVMDGQFVPNISIGLPILDAVRKGTTLPIDVHLMIENPEKNIASFAEHGADMISIHVESTPHIHRAIQMIKHLDKKAGVVINPGTPISQIEPILDIVDYVLVMTVNPGFGGQSFIDQCVEKIAGLNAIKMERQLNFDIEVDGGVNTDTAKVCVENGATMLVTGSFFFKQEDYKKVTQALKG
>CP022900.1|AXJ53540.1|1215535_1215769_+|Acyl-carrier-protein
MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK
>CP022900.1|AXJ53541.1|1215884_1216616_+|Ribonuclease-3
MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFINDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIFANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFPHVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAEGKGKTKKESEQRAAESAYKQLKQIK
>CP022900.1|AXJ53542.1|1216762_1220329_+|Chromosome-partition-protein-Smc
MVYLKSIDAIGFKSFADQTNVQFDKGVTAIVGPNGSGKSNITDAIKWVLGEQSAKSLRGSKMEDIIFSGAEHRKAQNYAEVQLRLDNHSKKLSVDENEVIVTRRLYRSGESEYYINNDRARLKDIADLFLDSGLGKEAYSIISQGRVDEILNAKPIDRRQIIEESAGVLKYKKRKAESLNKLDQTEDNLTRVEDILYDLEGRVEPLKEEAAIAKEYKTLSHQMKHSDIVVTVNDIDQYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKGKRHQLDNDVESLNYQLVKATEAFEKYTGQLNVLVERKKNQSETNARYEEEQENLIELLENISSEISEAQDTYKSLKSKQKELNAVIRELEEQLYVSDEAHDEKLEEIKNEYYTLMSEQSDVNNDIRFLKHTIEENEVKKSRLDSRLVEVFEQLKDIQGQIKTTKKEYQQTNKELSAVDKEIKNIEKDLTDTKKAQNEYEEKLYQAYRYTEKMKTRIDSLATQEEEYTYFFNGVKHILKAKNKELKGIHGAVAEIIDVPSKLTQAIETALGASLQHVIVDSEKDGRQAIQFLKERNLGRATFLPLNVIQSRAVATDIKSIAKEANGFISIASEAVKVAPEYQNIIGNLLGNTIIVDHLKHANELARAIKYRTRIVTLEGDIVNPGGSMTGGGARKSKSILSQKDELTTMRHQLEDYLRQTESFEQQFKELKIKSDQLSELYFEKSQKHNTLKEQVHHFEMELDRLTTQETQIKNDHEEFEFEKNDGYTSDKSRQTLSEKETHLESIKASLKRLEDEIERYTKLSKEGKESLTKTQQTLHQKQSDLAVVKERIKTQQQTIDRLNNQSQQTKHQLNDVKEKIAFFNSDEVMGEQAFQNIKDQINGQQETRTRLSDELDKLKQQRIELNEQIDAQEATLQVCHQDILAIENHYQDIKAEQSKLDVLIHHAIDHLNDEYQLTVERAKSEYTSDESIDALRKKVKLMKMSIDELGPVNLNAIEQFEELNERYTFLSEQRTDLRKAKETLEQIISEMDQEVTERFKETFHAIQGHFTAMFKQLFGGGDAELQLTEADYLTAGIDIVVQPPGKKLQHLSLLSGGERALTAIALLFAILKVRSAPFVILDEVEAALDEANVIRYAKYLNELSDETQFIVITHRKGTMEFADRLYGVTMQESGVTKLVSVNLNTIDDVLKEEQ
>CP022900.1|AXJ53543.1|1220328_1221579_+|Signal-recognition-particle-receptor-FtsY
MSFFKRLKDKFATNKENDEVKSLTEEQGQDKLEDTHSEGSTQDVNDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQLNNLISRYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVIVEKIVEIYHQEDDNSEAMNLEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVGVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNALSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNEEITTVENDQIVTEEKDDNHGAK
>CP022900.1|AXJ53544.1|1221565_1221898_+|putative-DNA-binding-protein
MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKKHLSNPEQIQRYIQQLEDLE
>CP022900.1|AXJ53545.1|1221923_1223291_+|Signal-recognition-particle-protein
MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQDELTKLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPVYSEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIMLVVDSMTGQDAVNVAESFDDQLDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKKRIAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF
>CP022900.1|AXJ53546.1|1223725_1224001_+|30S-ribosomal-protein-S16
MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
>CP022900.1|AXJ53547.1|1224188_1224692_+|Ribosome-maturation-factor-RimM
MRVEVGQIVNTHGIKGEIKVKSNSDFTDVRFQPGQVLTVVHNNNDLEYTVKSHRVHKGLHMLTFEGINNINDIEHLKGSSIYQERDHEDIVLEENEFYYSDIIGCTVFDDQETPIGRVINIFETGANDVWVIKGSKEYLIPYIADVVKEVDVENKKIIITPMEGLLD
>CP022900.1|AXJ53548.1|1224691_1225429_+|tRNA-(guanine-N(1)-)-methyltransferase
MKIDYLTLFPEMFDGVLNHSIMKRAQENNKLQINTVNFRDYAINKHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTEQARVILMCPQGEPFSHQKAVELSKADHIVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNEQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKRPDLIEKYPLTNADKQILERYKIGLKKG
>CP022900.1|AXJ53549.1|1225531_1225882_+|50S-ribosomal-protein-L19
MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR

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Crispr_ID: CP022900_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022900_5

1938258-1938385

Orphan

Consensus_repeat	Method
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022900_5

>merge|CP022900|5|1938258-1938385|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTCATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTATTAAATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

>CP022900|5|5|1938258-1938385|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	ATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTATTA
AATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

Protein	Signature genes	Signature genes Name	Protein_function
CP022900.1\|AXJ54160.1\|1930417_1930813_-\|hypothetical-protein	unknown	unknown	unknown
CP022900.1\|AXJ54159.1\|1928836_1930222_-\|Fumarate-hydratase-class-II	unknown	unknown	gnl\|CDD\|234779
CP022900.1\|AXJ54162.1\|1931590_1932190_-\|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|223440
CP022900.1\|AXJ54174.1\|1953351_1953894_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184219
CP022900.1\|AXJ54166.1\|1934816_1936274_-\|Arginine-transport-system-permease-protein-ArtQ	unknown	unknown	gnl\|CDD\|223836
CP022900.1\|AXJ54158.1\|1927559_1928381_+\|Ribosomal-large-subunit-pseudouridine-synthase-D	unknown	unknown	gnl\|CDD\|223638
CP022900.1\|AXJ54168.1\|1946422_1946869_-\|Peroxide-responsive-repressor-PerR	unknown	unknown	gnl\|CDD\|223806
CP022900.1\|AXJ54167.1\|1936532_1937594_-\|Phosphotransferase-system,-EIIC	unknown	unknown	gnl\|CDD\|226167
CP022900.1\|AXJ54165.1\|1934101_1934830_-\|L-cystine-import-ATP-binding-protein-TcyC	unknown	unknown	gnl\|CDD\|224051
CP022900.1\|AXJ54175.1\|1954196_1955234_-\|putative-A/G-specific-adenine-glycosylase-YfhQ	unknown	unknown	gnl\|CDD\|224115
CP022900.1\|AXJ54176.1\|1955385_1956363_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224899
CP022900.1\|AXJ54163.1\|1932348_1932819_-\|tRNA-(cytidine(34)-2'-O)-methyltransferase	unknown	unknown	gnl\|CDD\|223297
CP022900.1\|AXJ54171.1\|1948457_1949747_+\|Glutamate-1-semialdehyde-2,1-aminomutase-2	unknown	unknown	gnl\|CDD\|183493
CP022900.1\|AXJ54177.1\|1956623_1957460_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224596
CP022900.1\|AXJ54164.1\|1932823_1933951_-\|Epoxyqueuosine-reductase	unknown	unknown	gnl\|CDD\|272993
CP022900.1\|AXJ54172.1\|1949988_1951134_+\|Fusaric-acid-resistance-protein-family-protein	unknown	unknown	gnl\|CDD\|226614
CP022900.1\|AXJ54173.1\|1951324_1953061_-\|Putative-multidrug-export-ATP-binding/permease-protein	unknown	unknown	gnl\|CDD\|224055
CP022900.1\|AXJ54169.1\|1946965_1947925_-\|Glyoxylate/hydroxypyruvate-reductase-B	unknown	unknown	gnl\|CDD\|240632
CP022900.1\|AXJ54170.1\|1947921_1948377_-\|Putative-peroxiredoxin-bcp	unknown	unknown	gnl\|CDD\|224146
CP022900.1\|AXJ54161.1\|1931413_1931566_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP022900.1\|AXJ54159.1\|1928836_1930222_-\|Fumarate-hydratase-class-II	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
CP022900.1\|AXJ54162.1\|1931590_1932190_-\|glucosamine-6-phosphate-deaminase	gnl\|CDD\|223440	COG0363, NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism].	9.77274e-11
CP022900.1\|AXJ54158.1\|1927559_1928381_+\|Ribosomal-large-subunit-pseudouridine-synthase-D	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	3.57209e-78
CP022900.1\|AXJ54166.1\|1934816_1936274_-\|Arginine-transport-system-permease-protein-ArtQ	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.55367e-98
CP022900.1\|AXJ54174.1\|1953351_1953894_-\|hypothetical-protein	gnl\|CDD\|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	1.0244e-125
CP022900.1\|AXJ54170.1\|1947921_1948377_-\|Putative-peroxiredoxin-bcp	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	1.5916e-68
CP022900.1\|AXJ54168.1\|1946422_1946869_-\|Peroxide-responsive-repressor-PerR	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	6.09298e-56
CP022900.1\|AXJ54167.1\|1936532_1937594_-\|Phosphotransferase-system,-EIIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	1.65132e-122
CP022900.1\|AXJ54165.1\|1934101_1934830_-\|L-cystine-import-ATP-binding-protein-TcyC	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.22702e-152
CP022900.1\|AXJ54175.1\|1954196_1955234_-\|putative-A/G-specific-adenine-glycosylase-YfhQ	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	4.67816e-157
CP022900.1\|AXJ54163.1\|1932348_1932819_-\|tRNA-(cytidine(34)-2'-O)-methyltransferase	gnl\|CDD\|223297	COG0219, CspR, Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis].	1.70324e-88
CP022900.1\|AXJ54171.1\|1948457_1949747_+\|Glutamate-1-semialdehyde-2,1-aminomutase-2	gnl\|CDD\|183493	PRK12389, PRK12389, glutamate-1-semialdehyde aminotransferase; Provisional.	0
CP022900.1\|AXJ54177.1\|1956623_1957460_-\|hypothetical-protein	gnl\|CDD\|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	0.000164936
CP022900.1\|AXJ54164.1\|1932823_1933951_-\|Epoxyqueuosine-reductase	gnl\|CDD\|272993	TIGR00276, iron-sulfur_cluster-binding_protein, epoxyqueuosine reductase. This model was rebuilt to exclude archaeal homologs, now that there is new information that bacterial members are epoxyqueuosine reductase, QueG, involved in queuosine biosynthesis for tRNA maturation. [Protein synthesis, tRNA and rRNA base modification].	6.7316e-180
CP022900.1\|AXJ54172.1\|1949988_1951134_+\|Fusaric-acid-resistance-protein-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	1.08084e-85
CP022900.1\|AXJ54173.1\|1951324_1953061_-\|Putative-multidrug-export-ATP-binding/permease-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
CP022900.1\|AXJ54169.1\|1946965_1947925_-\|Glyoxylate/hydroxypyruvate-reductase-B	gnl\|CDD\|240632	cd12155, PGDH_1, Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family. Phosphoglycerate Dehydrogenase (PGDH) catalyzes the NAD-dependent conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first step in serine biosynthesis. Over-expression of PGDH has been implicated as supporting proliferation of certain breast cancers, while PGDH deficiency is linked to defects in mammalian central nervous system development. PGDH is a member of the 2-hydroxyacid dehydrogenase family, enzymes that catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	2.33588e-135
CP022900.1\|AXJ54176.1\|1955385_1956363_+\|hypothetical-protein	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	1.21408e-39

>CP022900.1|AXJ54167.1|1936532_1937594_-|Phosphotransferase-system,-EIIC
MSNAKNADNKQFFSKILNSIGAGVVIALVPNALLGEVLKIFKSGNEILELTYQLVILIQSFMAFIIGVLAAHQFKFNGAGAAIVGTSAMIGSGAVVYSNNSFMLKGIGDIINTSLVVIIACLIYMVLQNKLGSFELIILPVLVPIVSGGIGLITLPYIRKITQAIGNVIHSFTDLNPLLMSILISVAFSLLMVTPISLVAIATAISLNGLGSGAANLGIVAACVTFLFGSLRVNSIGVNAVLLIGAAKMMIPVYLKNLIISIPLTINGIITGIIAYVLQVKGTPLSAGFGYTGLVGPINAFNRMSGDPTMNIILLALGYFVIPFVSAFIVHELCKKFIPIYSNDIYKFEVPKQ
>CP022900.1|AXJ54166.1|1934816_1936274_-|Arginine-transport-system-permease-protein-ArtQ
MKCLIRFILVLGLLISSAMVYINPAAYAEQDQKWEKIKERGELRVGLSADYAPMEFEHTVNGKTEYAGVDIDLAKKIAKDNNLKLKIVNMSFDSLLGALKTGKIDIIISGMTSTPERKKQVDFSDSYMMTKNIMLVKKDKVNDYKDIKDFNNKKVGAQKGTEQEKIAQTEIENASITSLSRLPDVILALKSGKVEGVVVEKPVAEAYLKQNPKLGISNVKFNEEEKDTVIAVPKDSPKLLSQINKTIKEVKDKGLIDKYMTNAANAMNDDSGFISKYGSFFLKGIKITILISLIGVALGSILGAFVALMKLSKIKIISWIASIYIEILRGTPMLVQVFIVFFGITAALGLDISALVCGTIALVINSSAYIAEIIRAGINAVDKGQMEAARSLGLNYRQTMKSVIMPQAIKNILPALGNEFVTLIKESSIVSTIGVGEIMFNAQVVQGISFDPFTPLLVAAALYFVLTFVLTRIMNMIEGRLNASD
>CP022900.1|AXJ54165.1|1934101_1934830_-|L-cystine-import-ATP-binding-protein-TcyC
MPVIKINNLNKVFGDNEVLKDINLEINQGEVVAIIGPSGSGKSTLLRCMNLLEVPTKGQVIFEGNDLTEKGTQVDKLRQKMGMVFQNFNLFPHKKVVDNIILAPKLLKKDNNDELHKEALSLLDKVGLKEKADVYPNQLSGGQKQRVAIARALAMHPDVILFDEPTSALDPEVVGDVLKVMKDLAKEGMTMVVVTHEMGFAKDVSDKVIFMADGVVVESGTPVEIFEQPQHERTQNFLARVL
>CP022900.1|AXJ54164.1|1932823_1933951_-|Epoxyqueuosine-reductase
MDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANGYASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWGQDYHTIMRKRLDMLAAFIESKVPDVEIKSMVDTGVLSDRAVAERAGLGFVGRNGFVINPKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFLTQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLRMSNKEFKQTYGHLAGAWRGKKPIQRNAILALAHFNEVDAIPELKKVATTDERPMIRATAYWAIGQILGEEARDFINANYDQEDAEVQNEMIKGLDTRRE
>CP022900.1|AXJ54163.1|1932348_1932819_-|tRNA-(cytidine(34)-2'-O)-methyltransferase
MTNHIVLYQPEIPANTGNIARTCAGTNTHLHLIKPLGFRTDDKMLKRAGLDYWEFVNITYHDSIEAFFEATNGEYYLLTKFGKKTYSDFDFSNHDKDFYFIFGKETTGLPDWVKEKYQDTALRIPMSEHIRSLNLSNTAALLIYEALRQQDFPGLN
>CP022900.1|AXJ54162.1|1931590_1932190_-|glucosamine-6-phosphate-deaminase
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNIEKHAVDFSQINILDYDDKKSYFEALGVPAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGKTSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
>CP022900.1|AXJ54161.1|1931413_1931566_-|hypothetical-protein
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
>CP022900.1|AXJ54160.1|1930417_1930813_-|hypothetical-protein
MLGKYWIQLLIATVIISLISIKAFPLAIGALYLPIIFKVIKLQLNLSKGLIDDVNAQTFIKSNQSGIVISVICCLLITGILYYTLDGFYASLTGVLGTLVALNPYTTIVSAVLYILTAIATVEATKTKYRN
>CP022900.1|AXJ54159.1|1928836_1930222_-|Fumarate-hydratase-class-II
MSVRIEHDTFGEIEVPADKYWGAQTERSKRNFPVGKERMPIEVVYGFAQLKRAAALANFDLGKLSEAKKDAIVYACDQILSGELDEHFPLVVWQTGSGTQSNMNVNEVVSYVANMYLKDHHSDESIHPNDDVNKSQSSNDTFPTAMHVALYQEVETKLEPALKLLRNTLKEKEDKFDSIIKIGRTHLQDATPIKLGQEISGWRYMLDRCETMLSESKKHILNLAIGGTAVGTGINAHPEFGDKVAQYISENTGYPFVSSENKFHALTAHDEVVQLHGTLKALAGDLMKIANDVRWLASGPRAGLAEISIPENEPGSSIMPGKVNPTQCEMLTMVAVQVMGNDTVVGFASSQGNFELNVYKPVIMHNTLQSIYLLADGMETFNNNCAVGIEPIEENIDNYLNQSLMLVTALNPHIGYEKAAQIAKKAHKEGLTLKESAIQTGYVTEEQFEAWIKPEDMVDPH
>CP022900.1|AXJ54158.1|1927559_1928381_+|Ribosomal-large-subunit-pseudouridine-synthase-D
MKFKIPENFNDLSLRDIFQQLKVPKKDLHHLNMSKDITINDKPARLMDKVHTGDDVFVPTIDEKSNYVPSYRYAQIKYEDDDMAIVMKPKGVKTHPNDLKESNTLMNHVIYTVDSDYVEPIHRLDQETVGLLIVAKNPLMKKILDRMLEDNDITRIYKANVKALLPLKPQTIDMPIGKDKFHSNKRRVSPTGQRAITHILTSKMIKETVCQLEIKLDTGRTHQIRVHLAEIGHPVIGDPLYGDSTLRQLELESYKIEFVHPLTKEVISVSLDD
>CP022900.1|AXJ54168.1|1946422_1946869_-|Peroxide-responsive-repressor-PerR
MSVEIESIEHELEESIASLRQAGVRITPQRQAILRYLISSHTHPTADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK
>CP022900.1|AXJ54169.1|1946965_1947925_-|Glyoxylate/hydroxypyruvate-reductase-B
MTYMKVVGLNRMREVETELQQRFSDVDFKFYKKASEIPESDLANLDILVGYDGGINEAFLRRCPNLKWIAWFATGVNTLPLDYIADHGILLTNGKGVQAKQLSEYILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQTVLFLGTGAIATRTAKLAKAFNMNLIGLSKSGQNKDEFDEIYTIESLESTLPNADIVINALPETQETIHLLKKKHFELMKDEALFINIGRGSIVKEVLLIEVLKSRVIRHAYLDVFENEPLKPNHELYELDNVTITAHITGNDYEAKYDLLDIFKNNLVNFLNKNGLIENEVDAKKGY
>CP022900.1|AXJ54170.1|1947921_1948377_-|Putative-peroxiredoxin-bcp
MLQKGEQFPIFKLENQDGTVITNDTLKGKKAIVYFYPRDNTPTCTTEACDFRDNLEMFNDLDVAVYGISGDSKKKHQNFIEKYGLNFDLLVDEDFKLAKETGVYQLKKSFGKESMGIVRTTFIIDEQGKVLDVIEKVKVKTQIEELKNILG
>CP022900.1|AXJ54171.1|1948457_1949747_+|Glutamate-1-semialdehyde-2,1-aminomutase-2
MNFSESERLQQLSNEYILGGVNSPSRSYKAVGGGAPVVMKEGHGAYLYDVDGNKFIDYLQAYGPIITGHAHPHITKAIQEQAAKGVLFGTPTELEIEFSKKLRDAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRNKIIKFAGSYHGHSDLVLVAAGSGPSQLGSPDSAGVPESVAREVITVPFNDINAYKEAIEFWGDEIAAVLVEPIVGNFGMVMPQPGFLEEVNEISHSNGTLVIYDEVITAFRFHYGAAQDLLGVIPDLTAFGKIVGGGLPIGGYGGRQDIMEQVAPLGPAYQAGTMAGNPLSMKAGIALLEVLEQDGVYEKLDSLGQQLEEGLLKLIEKHNITATINRIYGSLTLYFTDEKVTHYDQVEHSDGEAFGKFFKLMLNQGINLAPSKFEAWFLTTEHTEEDIKQTLKAADYAFSQMK
>CP022900.1|AXJ54172.1|1949988_1951134_+|Fusaric-acid-resistance-protein-family-protein
MNTNVRYSINLKGASLFLRLGARIFKTGIAIILAMSIASLLPDDVGLKALAGVSAVVAMQPSIYRSFKTVSDQALGNIIGAILSVTMVTIFSDNFIIMGVTVIVLIAILFKFNLAHVATLASVTALIIMGQHTGSFYITAFYRFVLVMIGVISSSLVNFVFLPPKFETKIYYNSLNISSDIFMWFKLVLNDTTEFNNIKQDSHNLKQRVEKLEKIYDYYSEERPITKKHIHQQNRKKILFREVVQTTRQAYEVLNKLSRYQNDLYLLNNNFLLQIKLDLDSLTAFHEQILASLSKKARYNVTHVDYELDNPQKKDLLSTFQHELINHPYQTEYSFANVMQIVAAIEEYRHHLEHLDRIRISFFTYHRSDADIEIVEEDFDL
>CP022900.1|AXJ54173.1|1951324_1953061_-|Putative-multidrug-export-ATP-binding/permease-protein
MIKRYLQFVKPYKYRIFATIIVGIIKFGIPMLIPLLIKYAIDGVINNHALTTDEKVHHLTIAIGIALFIFVIVRPPIEFIRQYLAQWTSNKILYDIRKKLYNHLQALSARFYANNQVGQVISRVINDVEQTKDFILTGLMNIWLDCITIIIALSIMFFLDVKLTLAALFIFPFYILTVYVFFGRLRKLTRERSQALAEVQGFLHERVQGISVVKSFAIEDNEAKNFDKKNTNFLTRALKHTRWNAYSFAAINTVTDIGPIIVIGVGAYLAISGSITVGTLAAFVGYLELLFGPLRRLVASFTTLTQSFASMDRVFQLIDEDYDIKNGVGAQPIEIKQGRIDIDHVSFQYNDNEAPILKDINLSIEKGETVAFVGMSGGGKSTLINLIPRFYDVTSGQILIDGHNIKDFLTGSLRNQIGLVQQDNILFSDTVKENILLGRPTATDEEVVEAAKMANAHDFIMNLPQGYDTEVGERGVKLSGGQKQRLSIARIFLNNPPILILDEATSALDLESESIIQEALDVLSKDRTTLIVAHRLSTITHADKIVVIENGHIVETGTHRELIAKQGAYEHLYSIQNL
>CP022900.1|AXJ54174.1|1953351_1953894_-|hypothetical-protein
MVRESIPKEGENIKIQSYKHDGKIHRVWSETTILKGTDHVVIGGNDHTLVTESDGRTWITREPAIVYFHSEYWFNVICMFREDGIYYYCNLSSPFVCDEEALKYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDIILRRNVDILQQWIEQKKGPFAPDFIKVWKDRYKKIRQY
>CP022900.1|AXJ54175.1|1954196_1955234_-|putative-A/G-specific-adenine-glycosylase-YfhQ
MYQQSSFKENLIHWFDENQREMPWRQTTNPYYIWLSEVMLQQTQVKTVIDYYHRFVERFPTVEVLSQASEDEVLKYWEGLGYYSRARNFHTAIKEVHDKYEGLVPKDPDQFKALKGVGPYTQAAVMSIAYNVPLATVDGNVFRVWSRLNDDYRDIKLQSTRKSYEQELLPYVTTEAGTFNQAMMELGALICTPKNPLCLFCPVQENCEAFDKGTFEKLPVKSKNVSKKVIEQSVFLIRNNQGQYLLQKRSEKLLHGMWQFPMFKSEHARREMTEKIGHDIQPVETPIFELKHQFTHLTWKIKVYAVSGTINIERLPDDMIWFDLSDRDQYTFPVPMSKIYQFING
>CP022900.1|AXJ54176.1|1955385_1956363_+|hypothetical-protein
MDTATHIAIGVGLTALATQDPAMASTFGATATTLIVGSLIPDGDTVLKLKDNATYISHHRGITHSIPFTILWPILITFLIFTFFSGTHPFHVWMWAQLAVFLHVFVDIFNSYGTQALRPITNKWIQLSVINTFDPIIFTVLCIGIVLWVVGLHPLAVFFPIIALLIIYYMIRFKMRAVIKQQALKAIQQEHHPVKVFVAPTIKFMEWRVAIQTDAHDYVGKAYGRNVVFSDKVERQKLSTDSILWKVKGNKDIRTFLNFSSIYRWQTTTLADGSTEIRLIDLRYLKNDHYSFVAIAHVTKDNVIDHSYIGWVFTEDKLQRKLYAK
>CP022900.1|AXJ54177.1|1956623_1957460_-|hypothetical-protein
MLDNIILYFKNLPHTKRYVTERLKQSWKSFLIVLAACLILIIASETLFSFSHLTDVKEVRWLFRLIALIVFAVLMFTIYISYHHYMNDFLVTKLFNISAATPVVIMSILSFIMLVILTMISALVKPVNFETSYIALFYFIVMATIFVGLISVTFGLIRLLTEKINIIFYGICVLCFLVLPIIFIPNPNHVFINHILMLNPMYYIVNGIAQSIIFGISSMENIPYHFYFILFLCLIAAVNFVLARYTTHAIYNKTSKVTQTDNQQDVSKDSTDEADTSS

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Click the colored protein region to show detailed information

Crispr_ID: CP022900_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022900_6

2021569-2021760

Orphan

Consensus_repeat	Method
NNTCTNTGTTGGGGCCCNCACC	CRT

3 spacers

DEDDh

The CRISPR arrays of CP022900_6

>merge|CP022900|6|2021569-2021760|CRT
CTCTATGTTTGGGGCCCCACCCCAACTTGCACATTATTGTAAGCTGACAGAAAGTCAGCTTCTATGTTGGGGCCCCGCCAACTTGCATTGTCTGTAGAATTTCCTTTCGAAATTCTCTTTGTTGGGGCCCCACCCTAACTTGCACATTATTGTAAGCTGACAGAAAGTCAGCTTCTTTGTTGGGGCCCCACT

>CP022900|6|1|2021569-2021760|CRT
CTCTATGTTTGGGGCCCCACC	CCAACTTGCACATTATTGTAAGCTGACAGAAAGTCAG
CTTCTATGTTGGGGCCCCGCC	AACTTGCATTGTCTGTAGAATTTCCTTTCGAAAT
TCTCTTTGTTGGGGCCCCACC	CTAACTTGCACATTATTGTAAGCTGACAGAAAGTCAG
CTTCTTTGTTGGGGCCCCACT

Protein	Signature genes	Signature genes Name	Protein_function
CP022900.1\|AXJ54257.1\|2011357_2012344_+\|Fusaric-acid-resistance-protein-family-protein	unknown	unknown	gnl\|CDD\|226614
CP022900.1\|AXJ54273.1\|2030663_2032856_-\|ATP-dependent-DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
CP022900.1\|AXJ54270.1\|2025817_2027356_+\|Sodium/proline-symporter	unknown	unknown	gnl\|CDD\|273981
CP022900.1\|AXJ54267.1\|2022249_2023677_-\|Aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase-subunit-B	unknown	unknown	gnl\|CDD\|235489
CP022900.1\|AXJ54261.1\|2015508_2016009_+\|Ferritin	unknown	unknown	gnl\|CDD\|224445
CP022900.1\|AXJ54260.1\|2013903_2015217_-\|UDP-N-acetylmuramate--L-alanine-ligase	unknown	unknown	gnl\|CDD\|223840
CP022900.1\|AXJ54259.1\|2013170_2013902_-\|cobyric-acid-synthase	unknown	unknown	gnl\|CDD\|225974
CP022900.1\|AXJ54266.1\|2020479_2021427_-\|Diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|183982
CP022900.1\|AXJ54268.1\|2023689_2025147_-\|Glutamyl-tRNA(Gln)-amidotransferase-subunit-A	unknown	unknown	gnl\|CDD\|234572
CP022900.1\|AXJ54271.1\|2027444_2028644_-\|CamS-sex-pheromone-cAM373-precursor	unknown	unknown	gnl\|CDD\|227188
CP022900.1\|AXJ54263.1\|2017020_2018091_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
CP022900.1\|AXJ54258.1\|2012532_2012946_-\|hypothetical-protein	unknown	unknown	unknown
CP022900.1\|AXJ54274.1\|2032852_2033545_-\|Heptaprenylglyceryl-phosphate-synthase	unknown	unknown	gnl\|CDD\|224560
CP022900.1\|AXJ54262.1\|2016399_2016954_+\|DNA-polymerase-III-PolC-type	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
CP022900.1\|AXJ54275.1\|2033727_2034030_-\|Trp-repressor-protein	unknown	unknown	gnl\|CDD\|226893
CP022900.1\|AXJ54276.1\|2034138_2035434_-\|Adenylosuccinate-lyase	unknown	unknown	gnl\|CDD\|176464
CP022900.1\|AXJ54265.1\|2019037_2020399_-\|putative-RNA-methyltransferase	unknown	unknown	gnl\|CDD\|225174
CP022900.1\|AXJ54264.1\|2018337_2018868_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378690
CP022900.1\|AXJ54272.1\|2028656_2030660_-\|DNA-ligase	unknown	unknown	gnl\|CDD\|236137
CP022900.1\|AXJ54269.1\|2025148_2025451_-\|Aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase-subunit-C	unknown	unknown	gnl\|CDD\|178810

Protein	Function_ID	Function_description	E-value
CP022900.1\|AXJ54257.1\|2011357_2012344_+\|Fusaric-acid-resistance-protein-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	9.69605e-76
CP022900.1\|AXJ54273.1\|2030663_2032856_-\|ATP-dependent-DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
CP022900.1\|AXJ54270.1\|2025817_2027356_+\|Sodium/proline-symporter	gnl\|CDD\|273981	TIGR02121, Osmoregulated_proline_transporter, sodium/proline symporter. This family consists of the sodium/proline symporter (proline permease) from a number of Gram-negative and Gram-positive bacteria and from the archaeal genus Methanosarcina. Using the related pantothenate permease as an outgroup, candidate sequences from Bifidobacterium longum and several from archaea are found to be outside the clade defined by known proline permeases. These sequences, scoring between 570 and -40, define the range between trusted and noise cutoff scores. [Transport and binding proteins, Amino acids, peptides and amines].	0
CP022900.1\|AXJ54267.1\|2022249_2023677_-\|Aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase-subunit-B	gnl\|CDD\|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0
CP022900.1\|AXJ54261.1\|2015508_2016009_+\|Ferritin	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	1.15329e-74
CP022900.1\|AXJ54260.1\|2013903_2015217_-\|UDP-N-acetylmuramate--L-alanine-ligase	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	3.60835e-98
CP022900.1\|AXJ54259.1\|2013170_2013902_-\|cobyric-acid-synthase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	1.79354e-120
CP022900.1\|AXJ54266.1\|2020479_2021427_-\|Diacylglycerol-kinase	gnl\|CDD\|183982	PRK13337, PRK13337, putative lipid kinase; Reviewed.	0
CP022900.1\|AXJ54268.1\|2023689_2025147_-\|Glutamyl-tRNA(Gln)-amidotransferase-subunit-A	gnl\|CDD\|234572	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA.	0
CP022900.1\|AXJ54271.1\|2027444_2028644_-\|CamS-sex-pheromone-cAM373-precursor	gnl\|CDD\|227188	COG4851, CamS, Protein involved in sex pheromone biosynthesis [General function prediction only].	0
CP022900.1\|AXJ54263.1\|2017020_2018091_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
CP022900.1\|AXJ54274.1\|2032852_2033545_-\|Heptaprenylglyceryl-phosphate-synthase	gnl\|CDD\|224560	COG1646, COG1646, Predicted phosphate-binding enzymes, TIM-barrel fold [General function prediction only].	2.53994e-99
CP022900.1\|AXJ54262.1\|2016399_2016954_+\|DNA-polymerase-III-PolC-type	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
CP022900.1\|AXJ54275.1\|2033727_2034030_-\|Trp-repressor-protein	gnl\|CDD\|226893	COG4496, COG4496, Uncharacterized protein conserved in bacteria [Function unknown].	1.66593e-59
CP022900.1\|AXJ54276.1\|2034138_2035434_-\|Adenylosuccinate-lyase	gnl\|CDD\|176464	cd01360, Adenylsuccinate_lyase_1, Adenylsuccinate lyase (ASL)_subgroup 1. This subgroup contains bacterial and archeal proteins similar to ASL, a member of the Lyase class I family. Members of this family for the most part catalyze similar beta-elimination reactions in which a C-N or C-O bond is cleaved with the release of fumarate as one of the products. These proteins are active as tetramers. The four active sites of the homotetrameric enzyme are each formed by residues from three different subunits. ASL catalyzes two steps in the de novo purine biosynthesis: the conversion of 5-aminoimidazole-(N-succinylocarboxamide) ribotide (SAICAR) into 5-aminoimidazole-4-carboxamide ribotide (AICAR) and, the conversion of adenylsuccinate (SAMP) into adenosine monophosphate (AMP).	0
CP022900.1\|AXJ54265.1\|2019037_2020399_-\|putative-RNA-methyltransferase	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	0
CP022900.1\|AXJ54264.1\|2018337_2018868_-\|hypothetical-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.54005e-11
CP022900.1\|AXJ54272.1\|2028656_2030660_-\|DNA-ligase	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
CP022900.1\|AXJ54269.1\|2025148_2025451_-\|Aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase-subunit-C	gnl\|CDD\|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	5.296e-34

>CP022900.1|AXJ54266.1|2020479_2021427_-|Diacylglycerol-kinase
MRKRARIIYNPTSGKEQFKRELPDALIKLEKAGYETSAYATEKIGDATLEAERAMHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPFAYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGYFTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGGKLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE
>CP022900.1|AXJ54265.1|2019037_2020399_-|putative-RNA-methyltransferase
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMGSCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMVIFVTNGKNWPQKNAVVEKILDAFPNVTSIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYGVEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPSTQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
>CP022900.1|AXJ54264.1|2018337_2018868_-|hypothetical-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSAGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ
>CP022900.1|AXJ54263.1|2017020_2018091_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYRNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSTRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>CP022900.1|AXJ54262.1|2016399_2016954_+|DNA-polymerase-III-PolC-type
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>CP022900.1|AXJ54261.1|2015508_2016009_+|Ferritin
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEEAMFETHINYLTRIGDDSNALYLYEKELGTRTFDEE
>CP022900.1|AXJ54260.1|2013903_2015217_-|UDP-N-acetylmuramate--L-alanine-ligase
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNGDDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISRFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQAIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>CP022900.1|AXJ54259.1|2013170_2013902_-|cobyric-acid-synthase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHNFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEKQAKQVLIDRANRQKKSR
>CP022900.1|AXJ54258.1|2012532_2012946_-|hypothetical-protein
MKPTKVILKDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEIKFEFALFDSDMDNLKYIEYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMVTESGVSLRINVTKSGFTKFINELVSLH
>CP022900.1|AXJ54257.1|2011357_2012344_+|Fusaric-acid-resistance-protein-family-protein
MNGQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQEIILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>CP022900.1|AXJ54267.1|2022249_2023677_-|Aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase-subunit-B
MHFETVIGLEVHVELKTDSKMFSPSPAHFGAEPNSNTNVIDLAYPGVLPVVNKRAVDWAMRAAMALNMEIATESKFDRKNYFYPDNPKAYQISQFDQPIGENGYIDIEVDGETKRIGITRLHMEEDAGKSTHKGEYSLVDLNRQGTPLIEIVSEPDIRSPKEAYAYLEKLRSIIQYTGVSDVKMEEGSLRCDANISLRPYGQEKFGTKAELKNLNSFNYVRKGLEYEEKRQEEELLSGGEIGQETRRFDESTGKTILMRVKEGSDDYRYFPEPDIVPLYIDDAWKERVRQTIPELPDERKAKYVNELGLPAYDAHVLTLTKEMSDFFESTIEHGADVKLTSNWLMGGVNEYLNKNQVELLDTKLTPENLAGMIKLIEDGTMSSKIAKKVFPELAAKGGNAKQIMEDNGLVQISDEATLLKFVNEALDNNEQSVEDYKNGKGKAMGFLVGQIMKASKGQANPQLVNQLLKQELDKR
>CP022900.1|AXJ54268.1|2023689_2025147_-|Glutamyl-tRNA(Gln)-amidotransferase-subunit-A
MSIRYESVENLLTLIKDKKIKPSDVVKDIYDAIEETDPTIKSFLALDKENAIKKAQELDELQAKDQMDGKLFGIPMGIKDNIITNGLETTCASKMLEGFVPIYESTVMEKLHNENAVLIGKLNMDEFAMGGSTETSYFKKTVNPFDHKAVPGGSSGGSAAAVAAGLVPFSLGSDTGGSIRQPAAYCGVVGMKPTYGRVSRFGLVAFASSLDQIGPLTRNVKDNAIVLEAISGADANDSTSAPVDDVDFTSEIGKDIKGLKVALPKEYLGEGVADDVKEAVQNAVETLKSLGAVVEEVSLPNTKFGIPSYYVIASSEASSNLSRFDGIRYGYHSKEAHSLEELYKMSRSEGFGKEVKRRIFLGTFALSSGYYDAYYKKSQKVRTLIKNDFDKVFENYDVVVGPTAPTTAFNLGEEIDDPLTMYANDLLTTPVNLAGLPGISVPCGQSNGRPIGLQFIGKPFDEKTLYRVAYQYETQYNLHDVYEKL
>CP022900.1|AXJ54269.1|2025148_2025451_-|Aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase-subunit-C
MTKVTREEVEHIANLARLQISPEETEEMANTLESILDFAKQNDSADTEGVEPTYHVLDLQNVLREDKAIKGIPQELALKNAKETEDGQFKVPTIMNEEDA
>CP022900.1|AXJ54270.1|2025817_2027356_+|Sodium/proline-symporter
MLTMGTALSQQVDANWQTYIMIAVYFLILIVIGFYGYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWMIMGLPGSVYSTGLSAMWITIGLTLGAYINYFVVAPRLRVYTELAGDAITLPDFFKNRLNDKNNVLKIISGLIIVVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGYLAVSITDFFQGVIMLIAMVMVPIVAMMNLNGWGTFHDVAAMKPTNLNLFKGLSFIGIISLFSWGLGYFGQPHIIVRFMSIKSHKMLPKARRLGISWMAVGLLGAVAVGLTGIAFVPAYHIKLEDPETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLTEDFYKLVRGEEKAKTHQKEFVMVGRLSVLAVAIVAIAIAWNPNDTILNLVGNAWAGFGASFSPLVLFALYWKGLTRAGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIPGFIVSVIVTYVVSKLTKKPGAFVETDLNKVRDIVREK
>CP022900.1|AXJ54271.1|2027444_2028644_-|CamS-sex-pheromone-cAM373-precursor
MKRTLVLLITAIFILAACGNHKDDQAGKDNQKHNNSSNQVKEIATDKNVQGDNYRTLLPFKESQARGLLQDNMANSYNGGDFEDGLLNLSKEVFPTDKYLYQDGQFLDKKTINAYLNPKYTKREIDKMSEKDKKDKKANENLGLNPSHEGETDPEKIAEKSPAYLSNILEQDFYGGGDTKGKNIKGMTIGLAMNSVYYYKKEKDGPTFSKKLDDSEVKKQGKQMASEILSRLRENDDLKDIPIHFAIYKQSSEDSITPGEFITQATAEKSQTKLNEWHNINEKSALLPSSTAADYDENLNNNFKQFNDNLQSYFSNFTQAVGKVKFVDKKPQRLVVDLPIDYYGQAETIGITQYVTEQANKYFDKIDNYEIRIKDGNQPRALISKTKDDKEPQVHIYSN
>CP022900.1|AXJ54272.1|2028656_2030660_-|DNA-ligase
MADLSSRVNELHDLLNQYSYEYYVEDNPSVPDSEYDKLLHELIKIEEEHPEFKTVDSPTVRVGGEAQASFNKVNHDTPMLSLGNAFNEDDLRKFDQRIREQIGNVEYMCELKIDGLAVSLKYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPLNVEVRGEAYMPRRSFLRLNEEKEKNDEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFIYSVNDFTDFNARSQSEALDELDKLGFTTNKNRARVSDIDGVLEYIEKWTSQRESLPYDIDGIVIKVNDLDQQDEMGFTQKSPRWAIAYKFPAEEVVTKLLDIELSIGRTGVVTPTAILEPVKVAGTTVSRASLHNEDLIHDRDIRIGDSVVVKKAGDIIPEVVRSIPERRPEDAVTYHMPTHCPSCGHELVRIEGEVALRCINPKCQAQLVEGLIHFVSRQAMNIDGLGTKIIQQLYQSELIKDVADIFYLTEEDLLPLDRMGQKKVDNLLAAIQQAKDNSLENLLFGLGIRHLGVKASQVLAEKYETIDRLLTVTEAELVEIHDIGDKVAQSVVTYLENEDIRALIQKLKDKHVNMIYKGIKTSDIEGHPEFSGKTIVLTGKLHQMTRNEASKWLASQGAKVTSSVTKNTDVVIAGEDAGSKLTKAQSLGIEIWTEQQFVDKQNELNS
>CP022900.1|AXJ54273.1|2030663_2032856_-|ATP-dependent-DNA-helicase-PcrA
MNALLNHMNTEQSEAVKTTEGPLLIMAGAGSGKTRVLTHRIAYLLDEKDVSPYNVLAITFTNKAAREMKERVQKLVGDQAEVIWMSTFHSMCVRILRRDADRIGIERNFTIIDPTDQKSVIKDVLKNENIDSKKFEPRMFIGAISNLKNELKTPADAQKEATDYHSQMVATVYSGYQRQLSRNEALDFDDLIMTTINLFERVPEVLEYYQNKFQYIHVDEYQDTNKAQYTLVKLLASKFKNLCVVGDSDQSIYGWRGADIQNILSFEKDYPEANTIFLEQNYRSTKTILNAANEVIKNNSERKPKGLWTANTNGEKIHYYEAMTERDEAEFVIREIMKHQRNGKKYQDMAILYRTNAQSRVLEETFMKSNMPYTMVGGQKFYDRKEIKDLLSYLRIIANSNDDISLQRIINVPKRGVGPSSVEKVQNYALQNNISMFDALGEADFIGLSKKVTQECLNFYELIQSLIKEQEFLEIHEIVDEVLQKSGYREMLERENTLESRSRLENIDEFMSVPKDYEENTPLEEQSLINFLTDLSLVADIDEADTENGVTLMTMHSAKGLEFPIVFIMGMEESLFPHIRAIKSEDDHEMQEERRICYVAITRAEEVLYITHATSRMLFGRPQSNMPSRFLKEIPESLLENHSSGKRQTIQPKAKPFAKRGFSQRTTSTKKQVSSSDWNVGDKVMHKAWGEGMVSNVNEKNGSIELDIIFKSQGPKRLLAQFAPIEKKED
>CP022900.1|AXJ54274.1|2032852_2033545_-|Heptaprenylglyceryl-phosphate-synthase
MYDIKKWRHIFKLDPAKHISDDDLDAICMSQTDAIMIGGTDDVTEDNVIHLMSRVRRYPLPLVLEISNIESVMPGFDFYFVPTVLNSTDVAFHNGTLLEALKTYGHSIDFEEVIFEGYVVCNADSKVAKHTKANTDLTTEDLEAYAQMVNHLYRLPVMYIEYSGIYGDVSKVQAVSEHLTETQLFYGGGISSEQQATEMAAIADTIIVGDIIYKDIKKALKTVKIKESSK
>CP022900.1|AXJ54275.1|2033727_2034030_-|Trp-repressor-protein
MQIEKLRGAALDELFDAILTLENREECYQFFDDLCTVNEIQSLSQRLQVAKMIKQGYTYATIEQESGASTATISRVKRSLQWGNDAYTMILDRMNIETNE
>CP022900.1|AXJ54276.1|2034138_2035434_-|Adenylosuccinate-lyase
MIERYSREEMSNIWTDQNRYEAWLEVEILACEAWSELGHIPKADVQKIRQNAKVNVERAQEIEQETRHDVVAFTRQVSETLGEERKWVHYGLTSTDVVDTALSFVIKQANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAEPTTFGVKMALWYTEMQRNLQRFKQVREEIEVGKMSGAVGTFANIPPEIESYVCKHLGIGTAPVSTQTLQRDRHAYYIATLALIATSLEKFAVEIRNLQKTETREVEEAFAKGQKGSSAMPHKRNPIGSENITGISRVIRGYITTAYENVPLWHERDISHSSAERIMLPDVTIALDYALNRFTNIVDRLTVFEDNMRNNIDKTFGLIFSQRVLLALINKGMVREEAYDKVQPKAMISWETKTPFRELIEQDESITSVLTKEELDECFDPKHHLNQVDTIFERAGLA

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Crispr_ID: CP022900_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022900_7

2088350-2088438

Orphan

Consensus_repeat	Method
GTTTTTGACTGACTTCTCAATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022900_7

>merge|CP022900|7|2088350-2088438|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCAATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAGTTTTTCGACTGACTTCTCAATCA

>CP022900|7|6|2088350-2088438|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCA	ATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAG
TTTTTCGACTGACTTCTCAATCA

Protein	Signature genes	Signature genes Name	Protein_function
CP022900.1\|AXJ54322.1\|2082780_2083404_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374630
CP022900.1\|AXJ54327.1\|2087066_2087450_-\|hypothetical-protein	unknown	unknown	unknown
CP022900.1\|AXJ54324.1\|2084092_2085802_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227806
CP022900.1\|AXJ54329.1\|2087639_2087795_-\|hypothetical-protein	unknown	unknown	unknown
CP022900.1\|AXJ54328.1\|2087451_2087655_-\|hypothetical-protein	unknown	unknown	unknown
CP022900.1\|AXJ54338.1\|2094763_2095390_+\|Nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
CP022900.1\|AXJ54340.1\|2097137_2097272_-\|Delta-hemolysin	unknown	unknown	gnl\|CDD\|173213
CP022900.1\|AXJ54332.1\|2088504_2089179_+\|Helix-turn-helix-domain-protein	unknown	unknown	gnl\|CDD\|379188
CP022900.1\|AXJ54323.1\|2083400_2083781_-\|hypothetical-protein	unknown	unknown	unknown
CP022900.1\|AXJ54326.1\|2086748_2087066_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369323
CP022900.1\|AXJ54339.1\|2095750_2096449_+\|2-oxoglutaramate-amidase	unknown	unknown	gnl\|CDD\|143607
CP022900.1\|AXJ54330.1\|2087791_2088109_-\|Helix-turn-helix-domain-protein	unknown	unknown	gnl\|CDD\|200128
CP022900.1\|AXJ54337.1\|2093352_2094567_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236768
CP022900.1\|AXJ54336.1\|2092584_2093328_+\|CAAX-amino-terminal-protease-self--immunity	unknown	unknown	gnl\|CDD\|376806
CP022900.1\|AXJ54341.1\|2097453_2098071_+\|Accessory-gene-regulator-protein-B	unknown	unknown	gnl\|CDD\|214819
CP022900.1\|AXJ54334.1\|2090433_2092050_-\|60-kDa-chaperonin	unknown	unknown	gnl\|CDD\|234573
CP022900.1\|AXJ54325.1\|2085815_2086685_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|214926
CP022900.1\|AXJ54331.1\|2088113_2088332_-\|Helix-turn-helix-domain-protein	unknown	unknown	gnl\|CDD\|197775
CP022900.1\|AXJ54333.1\|2089192_2090365_+\|transposase	unknown	unknown	gnl\|CDD\|271189
CP022900.1\|AXJ54335.1\|2092125_2092410_-\|10-kDa-chaperonin	unknown	unknown	gnl\|CDD\|178988

Protein	Function_ID	Function_description	E-value
CP022900.1\|AXJ54322.1\|2082780_2083404_-\|hypothetical-protein	gnl\|CDD\|374630	pfam16560, SAPI, Putative mobile pathogenicity island. SAPI is a family of putative Gram-positive mobile pathogenicity island proteins. SAPIs are responsible for many superantigen-related diseases in humans as they carry two or more superantigens.	3.92354e-110
CP022900.1\|AXJ54338.1\|2094763_2095390_+\|Nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	7.96692e-115
CP022900.1\|AXJ54324.1\|2084092_2085802_-\|hypothetical-protein	gnl\|CDD\|227806	COG5519, COG5519, Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair].	2.17313e-165
CP022900.1\|AXJ54332.1\|2088504_2089179_+\|Helix-turn-helix-domain-protein	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.58614e-10
CP022900.1\|AXJ54341.1\|2097453_2098071_+\|Accessory-gene-regulator-protein-B	gnl\|CDD\|214819	smart00793, AgrB, Accessory gene regulator B. The accessory gene regulator (agr) of Staphylococcus aureus is the central regulatory system that controls the gene expression for a large set of virulence factors. The arg locus consists of two transcripts: RNAII and RNAIII. RNAII encodes four genes (agrA, B, C, and D) whose gene products assemble a quorum sensing system. At low cell density, the agr genes are continuously expressed at basal levels. A signal molecule, autoinducing peptide (AIP), produced and secreted by the bacteria, accumulates outside of the cells. When the cell density increases and the AIP concentration reaches a threshold, it activates the agr response, i.e. activation of secreted protein gene expression and subsequent repression of cell wall-associated protein genes. AgrB and AgrD are essential for the production of the autoinducing peptide which functions as a signal for quorum sensing. AgrB is a transmembrane protein. AgrB is involved in the proteolytic processing of AgrD and may have both proteolytic enzyme activity and a transporter facilitating the export of the processed AgrD peptide.	1.53656e-56
CP022900.1\|AXJ54340.1\|2097137_2097272_-\|Delta-hemolysin	gnl\|CDD\|173213	PRK14752, PRK14752, delta-lysin family phenol-soluble modulin.	8.25732e-15
CP022900.1\|AXJ54337.1\|2093352_2094567_-\|hypothetical-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	9.81296e-11
CP022900.1\|AXJ54336.1\|2092584_2093328_+\|CAAX-amino-terminal-protease-self--immunity	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.80796e-11
CP022900.1\|AXJ54339.1\|2095750_2096449_+\|2-oxoglutaramate-amidase	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	2.51836e-113
CP022900.1\|AXJ54330.1\|2087791_2088109_-\|Helix-turn-helix-domain-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	5.89089e-17
CP022900.1\|AXJ54326.1\|2086748_2087066_-\|hypothetical-protein	gnl\|CDD\|369323	pfam07342, DUF1474, Protein of unknown function (DUF1474). This family consists of several bacterial proteins of around 100 residues in length. Members of this family seem to be found exclusively in Staphylococcus aureus. The function of this family is unknown.	2.13556e-19
CP022900.1\|AXJ54334.1\|2090433_2092050_-\|60-kDa-chaperonin	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
CP022900.1\|AXJ54333.1\|2089192_2090365_+\|transposase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	5.10093e-47
CP022900.1\|AXJ54331.1\|2088113_2088332_-\|Helix-turn-helix-domain-protein	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	9.85461e-11
CP022900.1\|AXJ54325.1\|2085815_2086685_-\|hypothetical-protein	gnl\|CDD\|214926	smart00942, PriCT_1, Primase C terminal 1 (PriCT-1). This alpha helical domain is found at the C terminal of primases.	2.61429e-15
CP022900.1\|AXJ54335.1\|2092125_2092410_-\|10-kDa-chaperonin	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	5.94304e-45

>CP022900.1|AXJ54331.1|2088113_2088332_-|Helix-turn-helix-domain-protein
MTILANTRKFKEAMFLKGFNLSDLSRETGVGISYLSQIINGKKIPSPKLAKKMAEVLQVEVNELFEFEVKEA
>CP022900.1|AXJ54330.1|2087791_2088109_-|Helix-turn-helix-domain-protein
MFNINIDEDEARELLEQAINARVDELAKEKYFMTYKELSNYLNLSKPTIEELLINNGMKYYMVGSTYRFKKSDVDEFMEQLTAHMNIQNNDFKQVNIKKLLEARQ
>CP022900.1|AXJ54329.1|2087639_2087795_-|hypothetical-protein
MKIYLTYICLVSLLTILLLAISNMYVAFSVYAWLITLGCNLTGEITTCENK
>CP022900.1|AXJ54328.1|2087451_2087655_-|hypothetical-protein
MRKQVIITKTVVGWYNIKDTQHNLMLNIPPKVFEQYFPDVSKDVQVVCLEMDLSKITEIKNKKKVGS
>CP022900.1|AXJ54327.1|2087066_2087450_-|hypothetical-protein
MEIKQKYQLSKVVKILEVVLYEEDKFQSDKDYHYQDKALYEYALKLVHNGLFNILAELDFEDEAFLILDEVTMTLSDVMKETQHVYRYSVIDEKGEHKHTTDRKGHVIGMLEWALDYIAGNIEVEEL
>CP022900.1|AXJ54326.1|2086748_2087066_-|hypothetical-protein
MNWEIKDLMCDIEAVKEKINDVAIKHAWFVEDRFVKNELETKREHINFSASYLEHRIQNEHTVELLHVYLKEFGELIQKFHEIEKASSENFGEVSDDAQKLKITE
>CP022900.1|AXJ54325.1|2085815_2086685_-|hypothetical-protein
MNEIKLEYDTHVSVVHYESLDSRSFNSFSKINWSKLVNKLSVPIEANYKYARGVAVYGDIKNGANDQGEIIKKHRNDKNVIYRDVIVLDYDEINDLKQLHEAISSALSNVAWFWHTSYSHRTEQARIRLYIPLNERISADDYRKYTKVLANKIGHKVDEGSYQPSRCFALPVIQKGHIFIKRVNDCPIMNVDMLEQWSKEFEQSNASPNVIGYTRRDSEYWRELCFGTTEGNRNNALASLIGHLLRCHVNDYIVYSFALLWGQFACKPPMKEQEINATFQSILNKHYNN
>CP022900.1|AXJ54324.1|2084092_2085802_-|hypothetical-protein
METGKSDVLDKIEKINKKDSGLQEIIPKGYEIEHHQCGIALNQLIPSKKEGEPDKKVFITSTIPQITERFEDIESNEVSFNMLFYDNKTPVNIAVSAEEISDSRQLLKLVNKKLDVTSSTSTKLVDYINASKRYNPPLNVKVATRLGHVKGYFIYPYQEVMKDSNIKLFSNDKGFQKLIDSFQSKGTLEGYSKKVFGQIKDLPMVMVMLYASLGSVLLREFGLQPFIVEISGSTSTGKTFTLNLVSSVWGTSDLITTWSSTQNSIESMASFLNSFPMFKDDTRNTHPKFVTSATYNFSSGESKSRSNINLTLNAKKEWRNILISTGESSIANMADEKAGVSARVVTLQDPPYPDNFDFTTLDKSFRENYGTLGLAFIKQYESKKDVYKNAFESYQRYFNQKGSNEIMQRLGRAFALLQVTGEVLNDIDGFEHDHFKIIEQAYDSMVKNNKTIDKPKQLLEELLQYLDANRNNIAGDGYSSVKNGDIKAIYKRDYLCILGQTVHDKLGHEMQTITGQWGKKGYLIKGEKDRLQKKVSHKNIKYRGFAINKEMLEELGFDFSNSHNPYSDY
>CP022900.1|AXJ54323.1|2083400_2083781_-|hypothetical-protein
MDKEQLKKYIYDYVKEYKEIPIYQLEDLFKEMNHDYIGRTSVTHDKDENIVFWSGWNKITMFALIELVKSEQLDLVYRGSFVMRYLLDGRVPNLPLAICYPEDGQQTDVPSWVPMVLRINKEEKIK
>CP022900.1|AXJ54322.1|2082780_2083404_-|hypothetical-protein
MNIETIVNQFETRAGTLLRYYTGLLEHSKVQPCCFKLYNDPFDMAYVMMNGKLFGHVYIKDCKVRQSFELASPKHTEGLIRSIEGHYVGYELHDGKQLSISDMMASQLFEDEYFMYGLQTYAESNNSDVFEYLENGFDTDTLEGIQSSNTDVIANIEMLYQLATGINEPAPELVEGLRLVTEFVQDENATQEDYKALEHKLTELKSV
>CP022900.1|AXJ54332.1|2088504_2089179_+|Helix-turn-helix-domain-protein
MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRYDAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIENFDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSLSAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKSTTLHKEILQTDSRLSSDIFKEY
>CP022900.1|AXJ54333.1|2089192_2090365_+|transposase
MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHAEMVERQLRNGDYIAPSTSTFKQVADDWISQYANEVKVSSVRAREKAINHAIERFNNKPIQTINKHEYQRFVNDISAQYSKNYVDSIIASTNMIFKYAYDMKLIRIMPSEGIKRPKKKISVEELEDTEIHKKFLEKDELFQFLEVAKNHHSPQNSFEVFCTLAYTGMRAGELLALKWSDIDFENNTINITKTYYNPNNNKKQFQILTPKTESSIGKISVDPHVIKLLKNYKTDVQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTDITNKQISTHSFRHTHCALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSKLMENVSKDLF
>CP022900.1|AXJ54334.1|2090433_2092050_-|60-kDa-chaperonin
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDATIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEVGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>CP022900.1|AXJ54335.1|2092125_2092410_-|10-kDa-chaperonin
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>CP022900.1|AXJ54336.1|2092584_2093328_+|CAAX-amino-terminal-protease-self--immunity
MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVVSIVYTQIFGTQQTSPNTERLIVIARKIPLFIFFVSIVGPLLEEYVFRKVIFGELFNAIKGNRIVAFAIATTVSSLIFALAHNDYKFIPIYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>CP022900.1|AXJ54337.1|2093352_2094567_-|hypothetical-protein
MSYHWFKKMLLSTSMLILSSSSSLGLATHTVEAKDNLNGEKPTTNLNHNVTSPSVNSEMNNNETGTPHESNQAGNEGTGSNSRDANPDSNNVKPDSNNQNPSPDSKPDPNNPNPGPNPKPDPDKPKPNPEPKPDPDKPKPNPDPKPDPDKPKPNPDPKPDPNPNPNPKPDPNKPNPNPSPNPNQPGDSNQSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINQLGKEYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>CP022900.1|AXJ54338.1|2094763_2095390_+|Nitroreductase-family-protein
MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYENQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSNEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK
>CP022900.1|AXJ54339.1|2095750_2096449_+|2-oxoglutaramate-amidase
MKVQIYQLPIIFGDSSKNETQITQWFEKNMNAEVDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNNQIFNTAFSVNKSGKLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESQIF
>CP022900.1|AXJ54340.1|2097137_2097272_-|Delta-hemolysin
MSCLILRIFILIKEGVISMAQDIISTIGDLVKWIIDTVNKFTKK
>CP022900.1|AXJ54341.1|2097453_2098071_+|Accessory-gene-regulator-protein-B
MIKDCTKSYNNSEESGVKLNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTLAYILNIFIFTLITNISFYLIRRYAHGAHAPSSFWCYIESITLFIVLPLLVLHFHINETLMMFLALLSVGVVIKYAPAATKKKPIPARLVKQKRYFSIIISTILFIITLFVKEPYTQFIQLGIIIQAITLLPIYYSKED

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Crispr_ID: CP022900_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022900_8

2238137-2238338

Orphan

Consensus_repeat	Method
TCCTTGGTTGGCAGGTGCAGCTGGATGTGCTGTA	PILER-CR

2 spacers

The CRISPR arrays of CP022900_8

>merge|CP022900|8|2238137-2238338|PILER-CR
TGCTTGGTTGGCAGGTGCTGCTTGATTTCCAGGTTGTGCTTGTGCAGCGTTATTCGGATCAGCTTGATTACCTTGTCCAGCTGGTTGTGCTGTACCTGCTGCCGGTTGTGCTGCGCCTCCTGCTGGATTAGCCTGTCCACCTTGGTTTGCTGGTTGTGCTGCTGGTTGTCCTTGGTTGGCAGGTGCAGCTGGCTGTGCTGTA

>CP022900|8|1|2238137-2238338|PILER-CR
TGCTTGGTTGGCAGGTGCTGCTTGATTTCCAGGT	TGTGCTTGTGCAGCGTTATTCGGATCAGCTTGATTACCTTGTCCAGCT
GGTTGTGCTGTACCTGCTGCCGGTTGTGCTGCGC	CTCCTGCTGGATTAGCCTGTCCACCTTGGTTTGCTGGTTGTGCTGCTGGTTGTCCTTGGTTGGCAGGTGCAGCT
GGCTGTGCTGTA

Protein	Signature genes	Signature genes Name	Protein_function
CP022900.1\|AXJ54460.1\|2229730_2230837_+\|Mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
CP022900.1\|AXJ54455.1\|2222079_2222862_-\|putative-ABC-transporter-ATP-binding-protein-YlmA	unknown	unknown	gnl\|CDD\|224044
CP022900.1\|AXJ54467.1\|2251527_2251923_-\|putative-transport-protein-HsrA	unknown	unknown	gnl\|CDD\|341046
CP022900.1\|AXJ54466.1\|2250479_2251568_-\|putative-multidrug-resistance-protein-EmrY	unknown	unknown	gnl\|CDD\|341046
CP022900.1\|AXJ54456.1\|2223093_2224899_-\|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]	unknown	unknown	gnl\|CDD\|234729
CP022900.1\|AXJ54462.1\|2240208_2241141_-\|YbbR-like-protein	unknown	unknown	gnl\|CDD\|227193
CP022900.1\|AXJ54452.1\|2216102_2217194_+\|hypothetical-protein	unknown	unknown	unknown
CP022900.1\|AXJ54470.1\|2254227_2254911_-\|hemolysin-III-related	unknown	unknown	gnl\|CDD\|224191
CP022900.1\|AXJ54451.1\|2214856_2215837_+\|Cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter	unknown	unknown	gnl\|CDD\|224151
CP022900.1\|AXJ54453.1\|2217481_2219128_+\|Transposase-DDE-domain-protein	unknown	unknown	gnl\|CDD\|226192
CP022900.1\|AXJ54468.1\|2252111_2252579_-\|Multidrug-resistance-efflux-pump-SepA	unknown	unknown	gnl\|CDD\|374975
CP022900.1\|AXJ54461.1\|2238826_2240182_-\|Phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
CP022900.1\|AXJ54454.1\|2221154_2222012_-\|Putative-phosphatase-YwpJ	unknown	unknown	gnl\|CDD\|223635
CP022900.1\|AXJ54457.1\|2225579_2227118_+\|PTS-system-mannitol-specific-EIICB-component	unknown	unknown	gnl\|CDD\|225123
CP022900.1\|AXJ54459.1\|2229296_2229731_+\|Mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014
CP022900.1\|AXJ54464.1\|2242141_2243050_-\|Arginase	unknown	unknown	gnl\|CDD\|212515
CP022900.1\|AXJ54463.1\|2241142_2241952_-\|DNA-integrity-scanning-protein-DisA	unknown	unknown	gnl\|CDD\|224539
CP022900.1\|AXJ54469.1\|2252706_2254050_-\|Multidrug-resistance-protein-3	unknown	unknown	gnl\|CDD\|129794
CP022900.1\|AXJ54458.1\|2227152_2229285_+\|Transcriptional-regulator-MtlR	unknown	unknown	gnl\|CDD\|226234
CP022900.1\|AXJ54465.1\|2249267_2250332_-\|Flagellum-site-determining-protein-YlxH	unknown	unknown	gnl\|CDD\|378455

Protein	Function_ID	Function_description	E-value
CP022900.1\|AXJ54460.1\|2229730_2230837_+\|Mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
CP022900.1\|AXJ54455.1\|2222079_2222862_-\|putative-ABC-transporter-ATP-binding-protein-YlmA	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.75723e-107
CP022900.1\|AXJ54467.1\|2251527_2251923_-\|putative-transport-protein-HsrA	gnl\|CDD\|341046	cd17503, MFS_LmrB_MDR_like, Bacillus subtilis lincomycin resistance protein (LmrB) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including Bacillus subtilis lincomycin resistance protein LmrB, and several proteins from Escherichia coli such as the putative MDR transporters EmrB, MdtD, and YieQ. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. For example, MMR confers resistance to the epoxide antibiotic methylenomycin. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.86553e-30
CP022900.1\|AXJ54466.1\|2250479_2251568_-\|putative-multidrug-resistance-protein-EmrY	gnl\|CDD\|341046	cd17503, MFS_LmrB_MDR_like, Bacillus subtilis lincomycin resistance protein (LmrB) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including Bacillus subtilis lincomycin resistance protein LmrB, and several proteins from Escherichia coli such as the putative MDR transporters EmrB, MdtD, and YieQ. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. For example, MMR confers resistance to the epoxide antibiotic methylenomycin. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.17545e-51
CP022900.1\|AXJ54456.1\|2223093_2224899_-\|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP022900.1\|AXJ54462.1\|2240208_2241141_-\|YbbR-like-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	4.21538e-117
CP022900.1\|AXJ54470.1\|2254227_2254911_-\|hemolysin-III-related	gnl\|CDD\|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	4.64044e-66
CP022900.1\|AXJ54451.1\|2214856_2215837_+\|Cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	4.09175e-108
CP022900.1\|AXJ54453.1\|2217481_2219128_+\|Transposase-DDE-domain-protein	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.2166e-37
CP022900.1\|AXJ54468.1\|2252111_2252579_-\|Multidrug-resistance-efflux-pump-SepA	gnl\|CDD\|374975	pfam17080, SepA, Multidrug Resistance efflux pump. SepA is a drug efflux protein that is involved in bacterial multidrug resistance. It is predicted to have four transmembrane domains.	8.07477e-30
CP022900.1\|AXJ54461.1\|2238826_2240182_-\|Phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
CP022900.1\|AXJ54454.1\|2221154_2222012_-\|Putative-phosphatase-YwpJ	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	1.15818e-59
CP022900.1\|AXJ54457.1\|2225579_2227118_+\|PTS-system-mannitol-specific-EIICB-component	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
CP022900.1\|AXJ54459.1\|2229296_2229731_+\|Mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	6.01856e-62
CP022900.1\|AXJ54464.1\|2242141_2243050_-\|Arginase	gnl\|CDD\|212515	cd09989, Arginase, Arginase family. This family includes arginase, also known as arginase-like amidino hydrolase family, and related proteins. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid. In vertebrates, at least two isozymes have been identified: type I (ARG1) cytoplasmic or hepatic liver-type arginase and type II (ARG2) mitochondrial or non-hepatic arginase. Point mutations in human arginase ARG1 gene lead to hyperargininemia with consequent mental disorders, retarded development and early death. Hyperargininemia is associated with a several-fold increase in the activity of the mitochondrial arginase (ARG2), causing persistent ureagenesis in patients. ARG2 overexpression plays a critical role in the pathophysiology of cholesterol mediated endothelial dysfunction. Thus, arginase is a therapeutic target to treat asthma, erectile dysfunction, atherosclerosis and cancer.	5.94976e-145
CP022900.1\|AXJ54463.1\|2241142_2241952_-\|DNA-integrity-scanning-protein-DisA	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.13611e-103
CP022900.1\|AXJ54469.1\|2252706_2254050_-\|Multidrug-resistance-protein-3	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.31901e-37
CP022900.1\|AXJ54458.1\|2227152_2229285_+\|Transcriptional-regulator-MtlR	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	9.39374e-67
CP022900.1\|AXJ54465.1\|2249267_2250332_-\|Flagellum-site-determining-protein-YlxH	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	5.47694e-116

>CP022900.1|AXJ54460.1|2229730_2230837_+|Mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALATGHQYDVILADESKTTTRVNNVAAINSMQPSEELKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLAYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>CP022900.1|AXJ54459.1|2229296_2229731_+|Mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEGNVDRIVQAKSAEEIKQVFEEADA
>CP022900.1|AXJ54458.1|2227152_2229285_+|Transcriptional-regulator-MtlR
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRITGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNLAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVKKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETRDKSSNMIDKDDVHIETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLISDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>CP022900.1|AXJ54457.1|2225579_2227118_+|PTS-system-mannitol-specific-EIICB-component
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWFPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFFGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLATLVSFVVAALIMKFTKEPKQDLEAATAQMETTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSLDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>CP022900.1|AXJ54456.1|2223093_2224899_-|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVTLQLISYYAALHRDLDVDKPRNLAKSVTVE
>CP022900.1|AXJ54455.1|2222079_2222862_-|putative-ABC-transporter-ATP-binding-protein-YlmA
MLIQLDQVGRMKQGKTILKNISWQINEGDKWILYGLNGAGKTTLLNILNAYEPATTGYVNLFGKMPGKVGYSTETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>CP022900.1|AXJ54454.1|2221154_2222012_-|Putative-phosphatase-YwpJ
MDNVKAIFLDMDGTILHENNQASTYTKDVINRLREKGYKVFLATGRSHSEIHQLVPEDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQIINLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIEHFGINQKETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>CP022900.1|AXJ54453.1|2217481_2219128_+|Transposase-DDE-domain-protein
MYKNYNMTQLTLPIETSVRIPQNDISRYVNEIVETIPDSEFDEFRHHRGATSYHPKMMLKIILYAYTQSVFSGRRIEKLLHDSIRLMWLAQNQTPSYKTINRFRVNPNTDALIESLFIQFHSQCLKQNLIDDNSIFIDGTKVEANANRYTFVWKKSIQNHESKLNENSKALYRDLVEEKIIPEIKEDGDSDLTIEEIDLIGSHLDKEIEDLNHSIQNEDCTQIRKQTRKKRTEIKKFKKKFDDYSERKSKYEEQKSILKDRNSFSKTDHDATFMRMKEDHMKNGQLKPGYNLQIATNSQFVLSYDLFQNPTDTRTLIPFLTMIQNTFGYLPEYIVADAGYGSEQNYMAIIDDFNKTPLITYGMFIKDKTRKFKSDIFNTQNWKYDELNDEFICPNNKRIGFKRYAYRNDRYGFKRDFKLYECDDCSACSLRQQCMKPNSKSNKKIMKNYNWEYFKAQINQKLSEPETKKIYSQRKIDVEPVFGFMKAILGFTRMSVRGINKVKRELGFVLMALNIRKIVARRAVYYQIHLKKADFYQIINRNQLFYIA
>CP022900.1|AXJ54452.1|2216102_2217194_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLVGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLVIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVITIILFVVIHAVILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>CP022900.1|AXJ54451.1|2214856_2215837_+|Cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALIAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVIATIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHSHHAHHHAHVH
>CP022900.1|AXJ54461.1|2238826_2240182_-|Phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
>CP022900.1|AXJ54462.1|2240208_2241141_-|YbbR-like-protein
MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKITGGEEQLNDIAYLKATFKTNKKINGDTKDIAEVTAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVSKAEPSETKAYINVK
>CP022900.1|AXJ54463.1|2241142_2241952_-|DNA-integrity-scanning-protein-DisA
MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQLLKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFLKRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNISQELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEVSDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK
>CP022900.1|AXJ54464.1|2242141_2243050_-|Arginase
MTKKKGIDIIGVPSTFGQRKLGVDLGPTAIRYAGLIPRLKQLDLDVNDKGDIKVSAVDIEKFQSEQNGLRNYDEIIDVTQKLNKEVSASIENNRFPLVLGGDHSIAIGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLTYRESHFALELLHQSQSVTSMDLVEVNPLIDHNNHTAEQSVSLVGTFFGETLL
>CP022900.1|AXJ54465.1|2249267_2250332_-|Flagellum-site-determining-protein-YlxH
MLTVDQVKELIGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKVAMAQLGGAPQLDLQMAVVNVLKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGIDEKPGINGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVRWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
>CP022900.1|AXJ54466.1|2250479_2251568_-|putative-multidrug-resistance-protein-EmrY
MPLMQFTLFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIALVAFIFGLISISSYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPVVIGAMIISSIIIYLFIRRQFNISNALLNLSVFKNRTFALCTISSMIIMMSMVGPALLIPLYVQNSLALSALLFGLVIMPGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVYAIRMFSVSLLMMPINTTGINSLKNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFGAKIFSSTSPSHLTATEIKQQSIAIGVDISFAFVAVLVMAAYVIALFIREPKEIESNRRKF
>CP022900.1|AXJ54467.1|2251527_2251923_-|putative-transport-protein-HsrA
MAKVELTTRRRNFIVAVMLISAFVAILNQTLLNAALPSIMRELNINESTSQWLVTGFMLVNGVMIPLTAYLMDRIKTRPLYLAAMGTFLVGSIVAAMAPNFGVLMLARVIQAMGGRRTHAFNAIHIVYVIQ
>CP022900.1|AXJ54468.1|2252111_2252579_-|Multidrug-resistance-efflux-pump-SepA
MNYLKHKFYNLLTTIIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIVFAVEHLMDYFRKMLPENAYFRGATFHLISYMVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>CP022900.1|AXJ54469.1|2252706_2254050_-|Multidrug-resistance-protein-3
MRLKSIVTVIALILIMFMAAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLTRFKIIYIAIAGLTLFTVGSLMSGLSTHFSMLVISRVIQGFGSGVMMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVVWTFHFPEEETVAKSKFDTKGITLFYIFIGLIMFALLNQQHLYLNIIGFVLAILVALRLFNVEKKVSSPFLPVAEFNRMITLVFITDLLTAVCLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHHIEAKLSRKVIYLSSFTLLLLSSIIIAFGIKLPILIACVLILSGLSFGYIYTKDSVIVQEETSPIQMKKMMSFYGLTKNLGASIGSTIMGYLYALKSGLFGANLHNILGVVSLISVGLIVVWLIFYREAASQTKE
>CP022900.1|AXJ54470.1|2254227_2254911_-|hemolysin-III-related
MSKSSEKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLVLPYAAVHSYIAYGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMIYVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMGWVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLLHLIAILYFM

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Crispr_ID: CP022900_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022900_9

2296670-2296795

Orphan

Consensus_repeat	Method
CCTCTTTACTCGAAAGCTCACAAAACTCTTGATATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022900_9

>merge|CP022900|9|2296670-2296795|CRISPRCasFinder
CCTCTTTACTCGAAAGCTCACAAAACTCTTGATATCACTGGTTTCTCATGATTTTTTAATGTTTTTATTTTGAGTTACTCGAAAATTTTCCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCA

>CP022900|9|7|2296670-2296795|CRISPRCasFinder
CCTCTTTACTCGAAAGCTCACAAAACTCTTGATATCA	CTGGTTTCTCATGATTTTTTAATGTTTTTATTTTGAGTTACTCGAAAATTTT
CCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCA

Protein	Signature genes	Signature genes Name	Protein_function
CP022900.1\|AXJ54517.1\|2305192_2305561_-\|50S-ribosomal-protein-L17	unknown	unknown	gnl\|CDD\|235522
CP022900.1\|AXJ54513.1\|2301330_2302191_-\|Energy-coupling-factor-transporter-ATP-binding-protein-EcfA2	unknown	unknown	gnl\|CDD\|184205
CP022900.1\|AXJ54505.1\|2291901_2292327_+\|65-kDa-membrane-protein-precursor	unknown	unknown	gnl\|CDD\|367591
CP022900.1\|AXJ54508.1\|2296852_2298289_-\|Divergent-AAA-domain-protein	unknown	unknown	gnl\|CDD\|225420
CP022900.1\|AXJ54503.1\|2289726_2290581_-\|Murein-DD-endopeptidase-MepM	unknown	unknown	gnl\|CDD\|366703
CP022900.1\|AXJ54514.1\|2302187_2302997_-\|Energy-coupling-factor-transporter-ATP-binding-protein-EcfA1	unknown	unknown	gnl\|CDD\|184207
CP022900.1\|AXJ54506.1\|2292717_2293422_-\|Alpha-acetolactate-decarboxylase	unknown	unknown	gnl\|CDD\|226058
CP022900.1\|AXJ54516.1\|2304151_2304940_+\|Integrase-core-domain-protein	unknown	unknown	gnl\|CDD\|222853
CP022900.1\|AXJ54498.1\|2284905_2285199_-\|hypothetical-protein	unknown	unknown	unknown
CP022900.1\|AXJ54509.1\|2298637_2299036_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
CP022900.1\|AXJ54502.1\|2287240_2289667_+\|Hyaluronate-lyase-precursor	unknown	unknown	gnl\|CDD\|238517
CP022900.1\|AXJ54499.1\|2285153_2285279_-\|hypothetical-protein	unknown	unknown	unknown
CP022900.1\|AXJ54512.1\|2300534_2301341_-\|Energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
CP022900.1\|AXJ54511.1\|2299735_2300530_-\|tRNA-pseudouridine-synthase-A	unknown	unknown	gnl\|CDD\|234577
CP022900.1\|AXJ54510.1\|2299049_2299487_-\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
CP022900.1\|AXJ54504.1\|2290791_2291607_-\|putative-hydrolase	unknown	unknown	gnl\|CDD\|319792
CP022900.1\|AXJ54507.1\|2293458_2295123_-\|Acetolactate-synthase	unknown	unknown	gnl\|CDD\|236312
CP022900.1\|AXJ54515.1\|2303399_2304128_+\|Transposase	unknown	unknown	gnl\|CDD\|379233
CP022900.1\|AXJ54501.1\|2286417_2286834_-\|HTH-type-transcriptional-regulator-AdhR	unknown	unknown	gnl\|CDD\|133384
CP022900.1\|AXJ54500.1\|2285499_2286348_-\|putative-oxidoreductase	unknown	unknown	gnl\|CDD\|381359

Protein	Function_ID	Function_description	E-value
CP022900.1\|AXJ54517.1\|2305192_2305561_-\|50S-ribosomal-protein-L17	gnl\|CDD\|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	2.70058e-62
CP022900.1\|AXJ54513.1\|2301330_2302191_-\|Energy-coupling-factor-transporter-ATP-binding-protein-EcfA2	gnl\|CDD\|184205	PRK13646, cbiO, energy-coupling factor transporter ATPase.	0
CP022900.1\|AXJ54505.1\|2291901_2292327_+\|65-kDa-membrane-protein-precursor	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	8.17372e-34
CP022900.1\|AXJ54508.1\|2296852_2298289_-\|Divergent-AAA-domain-protein	gnl\|CDD\|225420	COG2865, COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription].	3.62307e-63
CP022900.1\|AXJ54515.1\|2303399_2304128_+\|Transposase	gnl\|CDD\|379233	pfam13518, HTH_28, Helix-turn-helix domain. This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.	2.03349e-13
CP022900.1\|AXJ54514.1\|2302187_2302997_-\|Energy-coupling-factor-transporter-ATP-binding-protein-EcfA1	gnl\|CDD\|184207	PRK13648, cbiO, cobalt transporter ATP-binding subunit; Provisional.	0
CP022900.1\|AXJ54506.1\|2292717_2293422_-\|Alpha-acetolactate-decarboxylase	gnl\|CDD\|226058	COG3527, AlsD, Alpha-acetolactate decarboxylase [Secondary metabolites biosynthesis, transport, and catabolism].	1.39507e-119
CP022900.1\|AXJ54503.1\|2289726_2290581_-\|Murein-DD-endopeptidase-MepM	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	1.20929e-22
CP022900.1\|AXJ54509.1\|2298637_2299036_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	2.2295e-82
CP022900.1\|AXJ54502.1\|2287240_2289667_+\|Hyaluronate-lyase-precursor	gnl\|CDD\|238517	cd01083, GAG_Lyase, Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.	0
CP022900.1\|AXJ54516.1\|2304151_2304940_+\|Integrase-core-domain-protein	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.91633e-47
CP022900.1\|AXJ54512.1\|2300534_2301341_-\|Energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	2.81787e-49
CP022900.1\|AXJ54511.1\|2299735_2300530_-\|tRNA-pseudouridine-synthase-A	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	1.21958e-120
CP022900.1\|AXJ54510.1\|2299049_2299487_-\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	4.91074e-100
CP022900.1\|AXJ54504.1\|2290791_2291607_-\|putative-hydrolase	gnl\|CDD\|319792	cd02605, HAD_SPP, sucrose-phosphatase, similar to Synechocystis sp PCC 6803 SPP. Sucrose-phosphatase (SPP; EC 3.1.3.24) catalyzes the dephosphorylation of sucrose-6(F)-phosphate (Suc6P)-the final step in the pathway of sucrose biosynthesis in plants and cyanobacteria. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.06188e-100
CP022900.1\|AXJ54507.1\|2293458_2295123_-\|Acetolactate-synthase	gnl\|CDD\|236312	PRK08617, PRK08617, acetolactate synthase AlsS.	0
CP022900.1\|AXJ54501.1\|2286417_2286834_-\|HTH-type-transcriptional-regulator-AdhR	gnl\|CDD\|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	5.51415e-41
CP022900.1\|AXJ54500.1\|2285499_2286348_-\|putative-oxidoreductase	gnl\|CDD\|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	3.15275e-150

>CP022900.1|AXJ54507.1|2293458_2295123_-|Acetolactate-synthase
MTDKKYTAADMVIDTLKNNGVEYVFGIPGAKIDYLFNALIDDGPELIVTRHEQNAAMMAQGIGRLTGKPGVVLVTSGPGVSNLTTGLLTATSEGDPVLALGGQVKRNDLLRLTHQSIDNAALLKYSSKYSEEVQDPESLSEVMTNAIRIATSGKNGASFISIPQDVISSPVESKAISLCQKPNLGVPSEQDINDVIEAIKNASFPVLLAGMRSSSADETNAIRKLVERTNLPVVETFQGAGVISRELENHFFGRVGLFRNQVGDELLRKSDLVVTIGYDPIEYEASNWNKELETQIINIDEVQAEITNYMQPKKELIGNIAKTIEMISEKVDEPFINQQHLDELEQLRTHIDEETGIKATHEEGILHPVEIIESMQKVLTDDTTVTVDVGSHYIWMARNFRSYNPRHLLFSNGMQTLGVALPWAISAALVRPNTQVVSVAGDGGFLFSSQDLETAVRKNLNIIQLIWNDGKYNMVEFQEEMKYKRSSGVDFGPVDFVKYAESFGAKGLRVTNQEELEAAIKEGYETDGPVLIDIPVNYKDNIKLSTNMLPDVFN
>CP022900.1|AXJ54506.1|2292717_2293422_-|Alpha-acetolactate-decarboxylase
MASVLYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNGEVIFLDGKAYHANEHKEFVELKGDELTPYATVTKFVADTSYETKDKSSEAVFAEIKEKMLSENLFSAVKISGLFKKMHVRMMPAQEPPYTRLIDSARRQPEQTETYVKGAVVGFFTPELFHGIGSAGFHVHFANDDRNFGGHVLDFEVEDVKVEIQNIETFEQHFPIQDEDFINANIDYKDIADEIREAE
>CP022900.1|AXJ54505.1|2291901_2292327_+|65-kDa-membrane-protein-precursor
MKLKSFVTATLALGLLSTVGAALPSHEASADSNNGYKEMTMDGYHTVPYTISVDGITALHRTYFVFPENKKVLYQEIDSKVKNQLASQRGVTTEKINNAQTATYTLTLNDGNKKVVNLKKNDDAKNSIDPSTIKQIQIVVK
>CP022900.1|AXJ54504.1|2290791_2291607_-|putative-hydrolase
MSKRLLLFDFDETYFKHNTNEEDLSHLREMEKLLEKLTNNNEVITVVLTGSTFQSVMDKMDQVNMTFKPLHIFSDLSSKMFTWNNGEYVESETYKKKVLSEPFLFEDIEDILHHISAQYNVEFIPQRAFEGNETHYNFYFHSTGNHNNDRRILEVLVRYANDQNYTARFSRSNPLAGDPENAYDIDFTPSNAGKLYATQFLMKKYNIPVKSILGFGDSGNDEAYLSYLEHAYLMSNSRDEALKQKFRLTKYPYYQGITLHVKEFVEGKYDY
>CP022900.1|AXJ54503.1|2289726_2290581_-|Murein-DD-endopeptidase-MepM
MNKTNFGDYLNKSKSRKIYKIFDQNLKREFSYWQFRKLFKSYTWQSDVHELKVCTQNDGTIEQIWIDKANQFGVAVTWKDNSIIGFVMRPLINYDAIKNETTLKYAVPTTDCYEVFWGGDNELYNYHYLYPHQRYAIDLVIKENHKTYKNLGKVNADYFCFGKDIIAPANGTVEKVVNGVQDNSIGSTKESQFLGNYIVIKHAENEYSLIAHLQQYSIIVNEGQNVKYGDIIGKVGNSGNSTEPHIHFQVMNDKNIEACTSLKIRFINNRELIKGDVVCGLQGE
>CP022900.1|AXJ54502.1|2287240_2289667_+|Hyaluronate-lyase-precursor
MTYRMKKWQKLSTITLLMAGVITLNGGEFRSIDKHQIAVADTNVQTTDYEKLRNIWLDVNYGYDKYDENNPDMKKKFEATENEAEKLLKEMKTESDRKYLWESSKDLDTKSADMTRTYRNIEKISEAMKHKNTKLKTDENKTKVKDALEWLHKNAYGKEPDKKVADLTSNFKNKTSRNTNLNWWDYEIGTPRALTNTLILLQEDFTDEEKKKYTAPIKTFAPDSDKILSSVGKSEPAKGGNLVDISKVKLLESIIEEDKDMMKKSIDSFNTVFTYAQNSATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPMIKETPFNDSNQNDTTLKSWIDDGFMPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDTMDKSTKAKYKKIVKTSVESDSSYKQTDYLSSYSDISKMKSLMEDSTISTNGLTQQLKIYNDMDRVTYHNKGLDFAFGLSMTSKNVARYESINGENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLDNEEPKSTDVKKSSKTFVGGTKFDDQHASIGMDFENQDKTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANDYKLYKDDTQTTNSDNQETNSLFLESTNSTQNNIGYHFLNESKITVKKESHTGKWSDINKSQKDIQKTDEYYEVTQKHSNTDSKYAYVLYPGLSKDVFKSKASKVTVVKQEDDFHVVKDNESVWAGINYSDSAKTFEINNTKVEVKAKGMFILTKKDDNTYECSFYNPESTNSVSDIESKISMTGYSIINKNTSTSNESGVRFELTK
>CP022900.1|AXJ54501.1|2286417_2286834_-|HTH-type-transcriptional-regulator-AdhR
MKTKEVVALMNISQDTLRYYEKVGVIPPVNRDENGYRIYNDNDLNWIYLVKNLRNAGVSIESLIEFCRLAQLPKNENIQAQQKQILNKQLEELNENLKTIHDARDLLQYKIDNYDNHIAKINASDNHDDNVERLWERK
>CP022900.1|AXJ54500.1|2285499_2286348_-|putative-oxidoreductase
MNHIEISKDVKIPVLGFGVFQIPQEQTAEAVKEAIKAGYRHIDTAQSYLNETEVGQGIEASGIDRSELFITTKVWIENVNYEDTIKSIERSLQRLNLDYIDLVLIHQPYNDVYGSWRALEELKETGKIKAIGVSNFGVDRIVDLGIHNQIQPQVNQIEINPFHQQEEQVAALQQENVVVEAWAPFAEGKNQLFQNQLLQAIADKYNKSIAQVILRWLVERDIVVLAKSVNPERMAQNLDIFDFELTEEDKQQIATLEESNSQFFSHADPEMIKALTSRELDV
>CP022900.1|AXJ54499.1|2285153_2285279_-|hypothetical-protein
MTYIPFSIITLITGIIMHMTMYFVKFECRKMPLFMTIIFTI
>CP022900.1|AXJ54498.1|2284905_2285199_-|hypothetical-protein
MSENAIIHDDYFYNLKAVKTHNIAKNVNKSLLNDKGVSIGKFIQKLKGKNPTWRYPKIKWTISKNKGQSYGGSYWKLINNKGKRIASLTKEGKILRE
>CP022900.1|AXJ54508.1|2296852_2298289_-|Divergent-AAA-domain-protein
MTSSKYIEYLQTEVEGQLLDRKRASINPKDVAQHISAFANAEGGKLVIGIEDNGEISGFNHSKAKKKEVYIEAPFEHLYRIPKYTYEIIEVKKRDGTMDEILIFDIEPSYDAIITLKDDSVYLRINDKSRKLTHNQITNLEYDRGSRRFEEELVEYSSIEDVNEELVDEFKQLLNTNVDNEKLLKARGFMREGKLTVAGLLLFSNHINVYLPGARIRFMRYEGTKEESGTRLNIVKDITFDKALPVAIREARAFINTQLREYTFLGKEGRFVTLPEYPEFAWFEGMINSIVHRRYDNQGDHIRIKMFDDRLEISSPGALPASVTLENIKEERYSRNPKLAAALTQYKWVRESNEGVGRIFDEMKQYFLDDPVYSEPNNSSVQLALKNNIIARKKRETGRVSNIITPELFESLNEQQELIVRHLYNQGELTASKIANIIQRSVPTARKRLKELEEMNIISTHGSSKNDPKRTYYLLGFE
>CP022900.1|AXJ54509.1|2298637_2299036_-|30S-ribosomal-protein-S9
MTLAQVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFESLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGLLTRDPRMKERKKPGLKAARRSPQFSKR
>CP022900.1|AXJ54510.1|2299049_2299487_-|50S-ribosomal-protein-L13
MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
>CP022900.1|AXJ54511.1|2299735_2300530_-|tRNA-pseudouridine-synthase-A
MRILVEIAYQGNNFLGFQIQQNGRTVQQQFEKLLQRIHKRHVRIHPSSRTDRGVHAIQQYFHFDTDLNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFHCRYDCVGKRYRYKVYQAQQRDPFQSGLKTFIPEPLDLDKMNRAAQQFIGTHDFTGFCSQKTEVESKVRTLYQSEIVKTDDGFDYIVTGSGFLYNMVRVLVAFLIEVGKGRHEVSDVPKLLESKNRKNVPFTAPAEGLYLEKIYLDENELLKDFGNDIKIHRKKSL
>CP022900.1|AXJ54512.1|2300534_2301341_-|Energy-coupling-factor-transporter-transmembrane-protein-EcfT
MKNKLIIGRYLPINSFVHHLDPRAKLMFVFLFIILIFFCHSPLTYLWMFALILFFMRLAKIQLWFLIKGLTPIFFFLIFTLMMHIFLTKGGYVLVEWHGITIETNGILEGLYISLRLIGIVMIATIMTLSTSPIDLTDAFERLLAPLKMFKLPVHQLSMIMSIALRFIPTLMDELDKIILAQKSRGSEISSGNIATRIKSFIPLLVPLFISAFQRAEELAVAMEVRGYDANVKRTSYRQLKWQLRDTLSLIMIIPIAIILFVLKYSGV
>CP022900.1|AXJ54513.1|2301330_2302191_-|Energy-coupling-factor-transporter-ATP-binding-protein-EcfA2
MIIRFDNVSYTYQKGTPYQHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPVRKRIGMVFQFPESQLFEDTVEREMIFGPKNFKMNLDEAKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVVDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILISHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKEKLADWHIGLPEIVQLQYDFEQKHQTKLKDIALTEEAFVSLYKEWQHEK
>CP022900.1|AXJ54514.1|2302187_2302997_-|Energy-coupling-factor-transporter-ATP-binding-protein-EcfA1
MEDKNSVIVFKNVSFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKDIGIVFQNPDNQFVGSIVKYDVAFGLENHAVPHDEMHRRVSEALEQVDMLERADYEPNALSGGQKQRVAIASVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAMEADHVIVMNKGTVYKEGTATEIFDHAEELTTIGLDLPFPIKINQMLGHQTSFLTYEGLVDQL
>CP022900.1|AXJ54515.1|2303399_2304128_+|Transposase
MSIKPKVDIDVLLYMFQEYEKGVSFQYLIDTLQLDINVNTLYPKYKYYKTHGIETLLTQKQYNHYSKELKLKVVNEYLNSNQSTQDIAIKYNIRSSTQVKNWIKMYTVGKEIKNQSPKTGVYIMKARKTTFEERVTIVEYYLNHKQSYREVAEHFNISYGQIYQWVHKYQAHGKNGLVDGRGKGKPKSMMTPEEQKEAEIQALKAQNRLLEMENDVLKKFQALEREMIQRENKSRHTKRSKR
>CP022900.1|AXJ54516.1|2304151_2304940_+|Integrase-core-domain-protein
MCRILGISRASYYKWVHYQSSELELENEQLKREIESIYHKYNGIYGYRRIYIYIRLKLGKQVNRKRIYRLMKELNLKAVIRQKRKPYRRSTPQITSENKLNRQFDIDTPNKVWLTDVTEFKIKEGSKIYLSAIYDLGAKRIVSYELGPSNNNQLVFKTFNQAIEKVENTKGILFHSDRGFQYTSKTFKHMLDECGMIQSMSRVSKCIDNGPMEGVWGTIKSEIFRGNKHFKFNSVEEATKTIHDFILFFNHERITLKMADSV
>CP022900.1|AXJ54517.1|2305192_2305561_-|50S-ribosomal-protein-L17
MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV

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Crispr_ID: CP022900_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022900_10

2336677-2336757

Orphan

Consensus_repeat	Method
TCTATGTTGGGGCCCCGCCAACTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022900_10

>merge|CP022900|10|2336677-2336757|CRISPRCasFinder
TCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTTCGTCACCTTCTATGTTGGGGCCCCGCCAATTTG

>CP022900|10|8|2336677-2336757|CRISPRCasFinder
TCTATGTTGGGGCCCCGCCAACTTG	CACATTATTGTAAGCTGACTTTTCGTCACCT
TCTATGTTGGGGCCCCGCCAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
CP022900.1\|AXJ54556.1\|2333057_2333309_+\|hypothetical-protein	unknown	unknown	unknown
CP022900.1\|AXJ54558.1\|2334227_2334668_+\|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
CP022900.1\|AXJ54569.1\|2342082_2343087_-\|Molybdopterin-synthase-adenylyltransferase	unknown	unknown	gnl\|CDD\|181084
CP022900.1\|AXJ54561.1\|2336900_2337923_-\|Cyclic-pyranopterin-monophosphate-synthase	unknown	unknown	gnl\|CDD\|274250
CP022900.1\|AXJ54564.1\|2338787_2339234_-\|Molybdopterin-synthase-catalytic-subunit	unknown	unknown	gnl\|CDD\|223391
CP022900.1\|AXJ54570.1\|2343254_2343860_-\|Sulfate/thiosulfate-import-ATP-binding-protein-CysA	unknown	unknown	gnl\|CDD\|226628
CP022900.1\|AXJ54563.1\|2338548_2338782_-\|Molybdopterin-synthase-sulfur-carrier-subunit	unknown	unknown	gnl\|CDD\|340452
CP022900.1\|AXJ54553.1\|2327615_2327933_+\|hypothetical-protein	unknown	unknown	unknown
CP022900.1\|AXJ54565.1\|2339247_2339733_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-adapter-protein	unknown	unknown	gnl\|CDD\|224677
CP022900.1\|AXJ54551.1\|2326165_2327074_-\|Membrane-transport-protein	unknown	unknown	gnl\|CDD\|223751
CP022900.1\|AXJ54566.1\|2339729_2340989_-\|Molybdopterin-molybdenumtransferase	unknown	unknown	gnl\|CDD\|238452
CP022900.1\|AXJ54568.1\|2341547_2342054_-\|Molybdenum-cofactor-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|223595
CP022900.1\|AXJ54562.1\|2337942_2338542_-\|putative-molybdenum-cofactor-guanylyltransferase	unknown	unknown	gnl\|CDD\|234725
CP022900.1\|AXJ54560.1\|2335973_2336324_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
CP022900.1\|AXJ54552.1\|2327206_2327371_+\|hypothetical-protein	unknown	unknown	unknown
CP022900.1\|AXJ54559.1\|2334660_2335872_+\|major-facilitator-superfamily-transporter	unknown	unknown	gnl\|CDD\|341042
CP022900.1\|AXJ54555.1\|2331403_2332669_-\|Lipid-II:glycine-glycyltransferase	unknown	unknown	gnl\|CDD\|225224
CP022900.1\|AXJ54554.1\|2328119_2331287_-\|Swarming-motility-protein-SwrC	unknown	unknown	gnl\|CDD\|223911
CP022900.1\|AXJ54567.1\|2341051_2341546_+\|Cyclic-pyranopterin-monophosphate-synthase-accessory-protein	unknown	unknown	gnl\|CDD\|236483
CP022900.1\|AXJ54557.1\|2333300_2334065_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379203

Protein	Function_ID	Function_description	E-value
CP022900.1\|AXJ54558.1\|2334227_2334668_+\|putative-HTH-type-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.58234e-15
CP022900.1\|AXJ54561.1\|2336900_2337923_-\|Cyclic-pyranopterin-monophosphate-synthase	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
CP022900.1\|AXJ54564.1\|2338787_2339234_-\|Molybdopterin-synthase-catalytic-subunit	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
CP022900.1\|AXJ54570.1\|2343254_2343860_-\|Sulfate/thiosulfate-import-ATP-binding-protein-CysA	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	1.03488e-114
CP022900.1\|AXJ54563.1\|2338548_2338782_-\|Molybdopterin-synthase-sulfur-carrier-subunit	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	2.40505e-24
CP022900.1\|AXJ54565.1\|2339247_2339733_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-adapter-protein	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	3.19119e-50
CP022900.1\|AXJ54551.1\|2326165_2327074_-\|Membrane-transport-protein	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	5.74078e-43
CP022900.1\|AXJ54566.1\|2339729_2340989_-\|Molybdopterin-molybdenumtransferase	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	7.37627e-158
CP022900.1\|AXJ54568.1\|2341547_2342054_-\|Molybdenum-cofactor-biosynthesis-protein-B	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	2.50849e-64
CP022900.1\|AXJ54562.1\|2337942_2338542_-\|putative-molybdenum-cofactor-guanylyltransferase	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
CP022900.1\|AXJ54560.1\|2335973_2336324_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
CP022900.1\|AXJ54569.1\|2342082_2343087_-\|Molybdopterin-synthase-adenylyltransferase	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	4.64376e-130
CP022900.1\|AXJ54559.1\|2334660_2335872_+\|major-facilitator-superfamily-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.47845e-73
CP022900.1\|AXJ54555.1\|2331403_2332669_-\|Lipid-II:glycine-glycyltransferase	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	2.47464e-141
CP022900.1\|AXJ54554.1\|2328119_2331287_-\|Swarming-motility-protein-SwrC	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
CP022900.1\|AXJ54567.1\|2341051_2341546_+\|Cyclic-pyranopterin-monophosphate-synthase-accessory-protein	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	5.35275e-97
CP022900.1\|AXJ54557.1\|2333300_2334065_-\|hypothetical-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38

>CP022900.1|AXJ54560.1|2335973_2336324_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>CP022900.1|AXJ54559.1|2334660_2335872_+|major-facilitator-superfamily-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGVIISLFIKVDFEVTNSKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFAIERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>CP022900.1|AXJ54558.1|2334227_2334668_+|putative-HTH-type-transcriptional-regulator
MLSQEFFNSFITIYRPYLKLTEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>CP022900.1|AXJ54557.1|2333300_2334065_-|hypothetical-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>CP022900.1|AXJ54556.1|2333057_2333309_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIALAIIHMGILAHSTYVYLY
>CP022900.1|AXJ54555.1|2331403_2332669_-|Lipid-II:glycine-glycyltransferase
MEKMHITNQEHDAFVKSNPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEIQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>CP022900.1|AXJ54554.1|2328119_2331287_-|Swarming-motility-protein-SwrC
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTSMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKTSASNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVTTIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKIDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>CP022900.1|AXJ54553.1|2327615_2327933_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>CP022900.1|AXJ54552.1|2327206_2327371_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>CP022900.1|AXJ54551.1|2326165_2327074_-|Membrane-transport-protein
MTEQFTMIILLIALGYFLKRINYIKATDSQVIATLVLNVTLPSLVIVNLNSAELKLSLSILPILMIIYGIVAKMIAVWFFRKYDNHMRGSVGMMTGAMNIGLFAYPLIEVIWPKTGLIYFGMADIGGAFVMFGITYFVGSYFSEGSDQFDFKYLGKKLLQSVPLVTYIVMFILNISHIHLPHVAIDFFSILSHANMPLSMILLGVMLNFTLERKYIPATIKYLCLHYGLALVAGLLVHVLLPVSDDMIKTTLLVTWMFPVGVAIISYGIQFKYRTLPFIGMTTNLTIIISIIILYVYQAVFV
>CP022900.1|AXJ54561.1|2336900_2337923_-|Cyclic-pyranopterin-monophosphate-synthase
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATADGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>CP022900.1|AXJ54562.1|2337942_2338542_-|putative-molybdenum-cofactor-guanylyltransferase
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>CP022900.1|AXJ54563.1|2338548_2338782_-|Molybdopterin-synthase-sulfur-carrier-subunit
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFENLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>CP022900.1|AXJ54564.1|2338787_2339234_-|Molybdopterin-synthase-catalytic-subunit
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>CP022900.1|AXJ54565.1|2339247_2339733_-|Molybdopterin-guanine-dinucleotide-biosynthesis-adapter-protein
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLTNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>CP022900.1|AXJ54566.1|2339729_2340989_-|Molybdopterin-molybdenumtransferase
MVVEKRNPIPVKEAIQRIVNQQSTMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETTTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQQDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>CP022900.1|AXJ54567.1|2341051_2341546_+|Cyclic-pyranopterin-monophosphate-synthase-accessory-protein
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIYKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFNWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQLDQ
>CP022900.1|AXJ54568.1|2341547_2342054_-|Molybdenum-cofactor-biosynthesis-protein-B
MGEHQNVKLNRTVKAAVLTVSDTRNFDTDKGGQCVLQLLQVDNVEVSDAHYTIVKDEKVAITTQVKKWLEEDVDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNDKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>CP022900.1|AXJ54569.1|2342082_2343087_-|Molybdopterin-synthase-adenylyltransferase
MSQERYSRQILFKQIGEIGQNKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIDHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRTACTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENTSITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>CP022900.1|AXJ54570.1|2343254_2343860_-|Sulfate/thiosulfate-import-ATP-binding-protein-CysA
MLKINLKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP022900_1	1.1\|806606\|33\|CP022900\|CRISPRCasFinder	806606-806638	33	CP022900.1	1039941-1039973	1	0.97
CP022900_1	1.1\|806606\|33\|CP022900\|CRISPRCasFinder	806606-806638	33	CP022900.1	2372003-2372035	1	0.97
CP022900_10	10.1\|2336702\|31\|CP022900\|CRISPRCasFinder	2336702-2336732	31	CP022900.1	1066219-1066249	1	0.968
CP022900_10	10.1\|2336702\|31\|CP022900\|CRISPRCasFinder	2336702-2336732	31	CP022900.1	1640329-1640359	1	0.968
CP022900_3	3.1\|914134\|26\|CP022900\|CRISPRCasFinder	914134-914159	26	CP022900.1	2112391-2112416	2	0.923
CP022900_3	3.1\|914134\|26\|CP022900\|CRISPRCasFinder	914134-914159	26	CP022900.1	2172475-2172500	2	0.923
CP022900_6	6.1\|2021590\|37\|CP022900\|CRT	2021590-2021626	37	CP022900.1	819872-819908	2	0.946
CP022900_6	6.2\|2021648\|34\|CP022900\|CRT	2021648-2021681	34	CP022900.1	257684-257717	2	0.941
CP022900_6	6.2\|2021648\|34\|CP022900\|CRT	2021648-2021681	34	CP022900.1	334357-334390	2	0.941
CP022900_6	6.2\|2021648\|34\|CP022900\|CRT	2021648-2021681	34	CP022900.1	773441-773474	2	0.941
CP022900_6	6.2\|2021648\|34\|CP022900\|CRT	2021648-2021681	34	CP022900.1	806645-806678	2	0.941
CP022900_6	6.2\|2021648\|34\|CP022900\|CRT	2021648-2021681	34	CP022900.1	1066156-1066189	2	0.941
CP022900_6	6.2\|2021648\|34\|CP022900\|CRT	2021648-2021681	34	CP022900.1	1760241-1760274	2	0.941
CP022900_6	6.2\|2021648\|34\|CP022900\|CRT	2021648-2021681	34	CP022900.1	2336641-2336674	2	0.941
CP022900_6	6.2\|2021648\|34\|CP022900\|CRT	2021648-2021681	34	CP022900.1	2479635-2479668	2	0.941
CP022900_10	10.1\|2336702\|31\|CP022900\|CRISPRCasFinder	2336702-2336732	31	CP022900.1	819996-820026	2	0.935
CP022900_10	10.1\|2336702\|31\|CP022900\|CRISPRCasFinder	2336702-2336732	31	CP022900.1	869265-869295	2	0.935
CP022900_10	10.1\|2336702\|31\|CP022900\|CRISPRCasFinder	2336702-2336732	31	CP022900.1	914095-914125	2	0.935
CP022900_10	10.1\|2336702\|31\|CP022900\|CRISPRCasFinder	2336702-2336732	31	CP022900.1	2011032-2011062	2	0.935

1. spacer 1.1|806606|33|CP022900|CRISPRCasFinder matches to position: 1039941-1039973, mismatch: 1, identity: 0.97

attgggaatccaatttctctttgttggggccca	CRISPR spacer
attgggaatccaatttctctgtgttggggccca	Protospacer
******************** ************

2. spacer 1.1|806606|33|CP022900|CRISPRCasFinder matches to position: 2372003-2372035, mismatch: 1, identity: 0.97

attgggaatccaatttctctttgttggggccca	CRISPR spacer
attgggaatccaatttctctttgttgggaccca	Protospacer
****************************.****

3. spacer 10.1|2336702|31|CP022900|CRISPRCasFinder matches to position: 1066219-1066249, mismatch: 1, identity: 0.968

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**************************** **

4. spacer 10.1|2336702|31|CP022900|CRISPRCasFinder matches to position: 1640329-1640359, mismatch: 1, identity: 0.968

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**************************** **

5. spacer 3.1|914134|26|CP022900|CRISPRCasFinder matches to position: 2112391-2112416, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggtgg	CRISPR spacer
cgcggccccaacacagaagctggcgg	Protospacer
** ********************.**

6. spacer 3.1|914134|26|CP022900|CRISPRCasFinder matches to position: 2172475-2172500, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggtgg	CRISPR spacer
cggggccccaacacaaaagctggcgg	Protospacer
***************.*******.**

7. spacer 6.1|2021590|37|CP022900|CRT matches to position: 819872-819908, mismatch: 2, identity: 0.946

ccaacttgcacattattgtaagctgacagaaagtcag	CRISPR spacer
ccaacttgcacattattgtaagctggcggaaagtcag	Protospacer
*************************.*.*********

8. spacer 6.2|2021648|34|CP022900|CRT matches to position: 257684-257717, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgcctgtagaatttcttttcgaaat	Protospacer
***********.************.*********

9. spacer 6.2|2021648|34|CP022900|CRT matches to position: 334357-334390, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtttgtagaatttcttttcgaaat	Protospacer
************.***********.*********

10. spacer 6.2|2021648|34|CP022900|CRT matches to position: 773441-773474, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtttgtagaatttcttttcgaaat	Protospacer
************.***********.*********

11. spacer 6.2|2021648|34|CP022900|CRT matches to position: 806645-806678, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgcctgtagaatttcttttcgaaat	Protospacer
***********.************.*********

12. spacer 6.2|2021648|34|CP022900|CRT matches to position: 1066156-1066189, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgcctgtagaatttcttttcgaaat	Protospacer
***********.************.*********

13. spacer 6.2|2021648|34|CP022900|CRT matches to position: 1760241-1760274, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtctgtagaatttctttttgaaat	Protospacer
************************.***.*****

14. spacer 6.2|2021648|34|CP022900|CRT matches to position: 2336641-2336674, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtctgtagaatttctttttgaaat	Protospacer
************************.***.*****

15. spacer 6.2|2021648|34|CP022900|CRT matches to position: 2479635-2479668, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtctgtagaatttctttttgaaat	Protospacer
************************.***.*****

16. spacer 10.1|2336702|31|CP022900|CRISPRCasFinder matches to position: 819996-820026, mismatch: 2, identity: 0.935

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctgactttacgtcagct	Protospacer
********************** ***** **

17. spacer 10.1|2336702|31|CP022900|CRISPRCasFinder matches to position: 869265-869295, mismatch: 2, identity: 0.935

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctggcttttcgtcagct	Protospacer
*****************.********** **

18. spacer 10.1|2336702|31|CP022900|CRISPRCasFinder matches to position: 914095-914125, mismatch: 2, identity: 0.935

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctgacttttcgccagct	Protospacer
*************************.** **

19. spacer 10.1|2336702|31|CP022900|CRISPRCasFinder matches to position: 2011032-2011062, mismatch: 2, identity: 0.935

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattatcgtaagctgacttttcgtcagct	Protospacer
********.******************* **

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

357866 : 376087

Staphylococcus_phage(90.48%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ52758.1\|357866_358058_-	hypothetical protein	U3PCX8	Staphylococcus_phage	4.9e-23	80.0
AXJ52759.1\|358301_358598_+	30S ribosomal protein S6	NA	NA	NA	NA
AXJ52760.1\|358618_359122_+	Single-stranded DNA-binding protein ssb	A0A1W6JPL9	Staphylococcus_phage	1.2e-60	74.7
AXJ52761.1\|359173_359416_+	30S ribosomal protein S18	NA	NA	NA	NA
AXJ52762.1\|359647_360367_-	PemK-like protein	Q4ZE81	Staphylococcus_phage	3.7e-23	29.8
AXJ52763.1\|360479_361694_-	Tyrosine recombinase XerD	Q4ZE80	Staphylococcus_phage	3.3e-221	97.3
AXJ52764.1\|361854_362478_-	Helix-turn-helix domain protein	NA	NA	NA	NA
AXJ52765.1\|362626_362791_+	Helix-turn-helix domain protein	NA	NA	NA	NA
AXJ52766.1\|362791_363064_+	hypothetical protein	Q4ZE77	Staphylococcus_phage	1.2e-43	94.4
AXJ52767.1\|363075_363249_+	hypothetical protein	NA	NA	NA	NA
AXJ52768.1\|363215_363419_+	hypothetical protein	A0A1W6JQF4	Staphylococcus_phage	2.0e-30	98.5
AXJ52769.1\|363420_363804_+	hypothetical protein	A0A1W6JQI7	Staphylococcus_phage	4.8e-62	96.1
AXJ52770.1\|363804_364131_+	hypothetical protein	Q4ZE75	Staphylococcus_phage	3.5e-53	96.3
AXJ52771.1\|364195_365065_+	hypothetical protein	Q4ZE74	Staphylococcus_phage	5.3e-165	96.2
AXJ52772.1\|365078_366788_+	hypothetical protein	Q4ZE73	Staphylococcus_phage	8.2e-303	92.8
AXJ52773.1\|367097_367478_+	hypothetical protein	Q4ZE71	Staphylococcus_phage	1.7e-67	96.8
AXJ52774.1\|367474_368116_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	4.7e-110	92.5
AXJ52775.1\|368823_369168_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	1.3e-50	91.7
AXJ52776.1\|369198_369852_+	hypothetical protein	Q4ZE82	Staphylococcus_phage	7.6e-116	99.5
AXJ52777.1\|369904_370432_+	hypothetical protein	Q4ZE87	Staphylococcus_phage	6.8e-91	100.0
AXJ52778.1\|370434_370776_+	hypothetical protein	Q4ZE86	Staphylococcus_phage	1.1e-57	98.2
AXJ52779.1\|370772_371342_+	Terminase small subunit	Q4ZE85	Staphylococcus_phage	4.6e-101	98.4
AXJ52780.1\|371618_372587_+	Abi-like protein	A0A0H4U080	Erysipelothrix_phage	2.7e-24	27.3
AXJ52781.1\|372764_373166_+	hypothetical protein	A0A2H4J577	uncultured_Caudovirales_phage	5.1e-22	59.1
AXJ52782.1\|373283_373796_+	hypothetical protein	Q4ZE83	Staphylococcus_phage	1.4e-69	100.0
AXJ52783.1\|374754_375762_-	Abi-like protein	NA	NA	NA	NA
AXJ52784.1\|375838_376087_-	Tyrosine recombinase XerD	Q4ZE80	Staphylococcus_phage	2.0e-24	73.4

DBSCAN-SWA_2

751822 : 759642

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ53116.1\|751822_752878_-	Histidine protein kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
AXJ53117.1\|752877_753564_-	Response regulator SaeR	NA	NA	NA	NA
AXJ53118.1\|753538_754012_-	DoxX	NA	NA	NA	NA
AXJ53119.1\|754353_754794_-	Electron transfer DM13	NA	NA	NA	NA
AXJ53120.1\|755073_755658_-	hypothetical protein	NA	NA	NA	NA
AXJ53121.1\|755756_756470_-	7-carboxy-7-deazaguanine synthase	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
AXJ53122.1\|756473_756893_-	6-carboxy-5,6,7,8-tetrahydropterin synthase	S4U060	uncultured_phage	6.3e-07	28.7
AXJ53123.1\|756894_757563_-	7-cyano-7-deazaguanine synthase	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
AXJ53124.1\|757913_758507_+	Anthranilate synthase component 2	A0A0P0IKJ1	Acinetobacter_phage	6.8e-39	44.0
AXJ53125.1\|758490_759642_+	Aminodeoxychorismate synthase component 1	S4VNU7	Pandoravirus	2.1e-23	36.1

DBSCAN-SWA_3

771614 : 785752

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ53134.1\|771614_772673_+	Histidinol-phosphate aminotransferase	A0A0H3TLT9	Faustovirus	5.7e-20	26.5
AXJ53135.1\|772831_773374_+	Putative 5'(3')-deoxyribonucleotidase	NA	NA	NA	NA
AXJ53136.1\|773378_773513_+	hypothetical protein	NA	NA	NA	NA
AXJ53137.1\|773925_774843_-	Putative lipid kinase	A0A1V0SBJ0	Catovirus	8.2e-07	22.0
AXJ53138.1\|775112_776618_-	Di-/tripeptide transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
AXJ53139.1\|776957_777458_-	NADPH-dependent 7-cyano-7-deazaguanine reductase	E7DN65	Pneumococcus_phage	2.7e-52	66.2
AXJ53140.1\|777477_778344_-	EamA-like transporter family protein	NA	NA	NA	NA
AXJ53141.1\|779145_779544_+	ribonucleotide reductase stimulatory protein	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
AXJ53142.1\|779506_781612_+	Ribonucleoside-diphosphate reductase subunit alpha 2	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
AXJ53143.1\|781731_782703_+	Ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
AXJ53144.1\|783079_784051_+	Fe(3+) dicitrate transport system permease protein FecD	A0A2H4IY97	uncultured_Caudovirales_phage	7.8e-141	80.2
AXJ53145.1\|784037_784994_+	Iron-uptake system permease protein FeuC	A0A2H4J116	uncultured_Caudovirales_phage	5.5e-06	60.0
AXJ53146.1\|784990_785752_+	putative siderophore transport system ATP-binding protein YusV	Q9EMR9	Amsacta_moorei_entomopoxvirus	7.2e-17	30.1

DBSCAN-SWA_4

1611949 : 1620261

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ53879.1\|1611949_1612735_-	High-affinity zinc uptake system ATP-binding protein ZnuC	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
AXJ53880.1\|1612860_1613751_-	putative endonuclease 4	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
AXJ53881.1\|1613760_1615107_-	DEAD-box ATP-dependent RNA helicase CshB	A0A1V0SIR5	Klosneuvirus	1.4e-55	34.0
AXJ53882.1\|1615220_1616321_-	Putative GTP cyclohydrolase 1 type 2	A0A1S5V250	Saudi_moumouvirus	3.0e-08	30.6
AXJ53883.1\|1616323_1617001_-\|tRNA	tRNA (adenine(22)-N(1))-methyltransferase	NA	NA	NA	NA
AXJ53884.1\|1617131_1618238_-	RNA polymerase sigma factor SigA	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
AXJ53885.1\|1618461_1620261_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.5e-54	36.0

DBSCAN-SWA_5

1689697 : 1698740

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ53953.1\|1689697_1690216_-	Adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
AXJ53954.1\|1690237_1692511_-	Single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	6.2e-64	29.3
AXJ53955.1\|1692713_1694993_-	bifunctional preprotein translocase subunit SecD/SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
AXJ53956.1\|1695267_1695528_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
AXJ53957.1\|1695546_1696686_-\|tRNA	Queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
AXJ53958.1\|1696708_1697734_-\|tRNA	S-adenosylmethionine:tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
AXJ53959.1\|1697735_1698740_-	Holliday junction ATP-dependent DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_6

1828468 : 1897375

Staphylococcus_phage(93.18%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ54066.1\|1828468_1835038_-	Extracellular matrix-binding protein ebh precursor	A0A2H4PQU6	Staphylococcus_phage	1.7e-295	88.7
AXJ54067.1\|1835361_1835673_-	molybdopterin biosynthesis protein MoeB	A0A2H4PQR9	Staphylococcus_phage	4.5e-50	96.1
AXJ54068.1\|1835694_1838112_-\|tRNA	Leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	98.8
AXJ54069.1\|1838400_1839582_-	Multidrug resistance protein MdtH	A0A2H4PQR6	Staphylococcus_phage	9.6e-218	99.7
AXJ54070.1\|1839692_1840646_+	coproporphyrinogen III oxidase	A0A2H4PQV5	Staphylococcus_phage	6.4e-79	99.3
AXJ54071.1\|1840642_1841206_+	16S rRNA m(4)C1402 methyltransferase	A0A2H4PQV0	Staphylococcus_phage	1.1e-99	95.7
AXJ54072.1\|1841324_1841726_-	HTH-type transcriptional regulator rot	NA	NA	NA	NA
AXJ54073.1\|1842298_1843126_-	Phospholipase YtpA	NA	NA	NA	NA
AXJ54074.1\|1843359_1844361_+	Proline dehydrogenase 1	A0A2H4PQT6	Staphylococcus_phage	5.0e-183	99.1
AXJ54075.1\|1844482_1844947_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.9e-68	97.4
AXJ54076.1\|1844959_1846141_-	Riboflavin biosynthesis protein RibBA	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
AXJ54077.1\|1846151_1846784_-	Riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	8.4e-112	99.0
AXJ54078.1\|1846790_1847834_-	Riboflavin biosynthesis protein RibD	A0A2H4PQS8	Staphylococcus_phage	5.9e-195	98.3
AXJ54079.1\|1848314_1849817_-	hypothetical protein	A0A2H4PQX2	Staphylococcus_phage	5.0e-30	98.6
AXJ54080.1\|1850459_1850774_+	Transcriptional repressor SdpR	A0A2H4PQT4	Staphylococcus_phage	1.7e-52	97.1
AXJ54081.1\|1850773_1852066_+	Arsenical pump membrane protein	A0A2H4PQU3	Staphylococcus_phage	2.6e-216	95.1
AXJ54082.1\|1852152_1853007_-	Bifunctional autolysin precursor	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
AXJ54083.1\|1853282_1853507_-	hypothetical protein	NA	NA	NA	NA
AXJ54084.1\|1853705_1854176_+	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	7.7e-70	85.8
AXJ54085.1\|1854288_1854732_+	hypothetical protein	NA	NA	NA	NA
AXJ54086.1\|1854718_1855162_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-49	77.4
AXJ54087.1\|1855459_1856095_+\|protease	CAAX amino terminal protease self- immunity	NA	NA	NA	NA
AXJ54088.1\|1856261_1856882_+\|protease	CAAX amino terminal protease self- immunity	NA	NA	NA	NA
AXJ54089.1\|1857339_1858053_-	Transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
AXJ54090.1\|1858311_1858614_+	hypothetical protein	NA	NA	NA	NA
AXJ54091.1\|1858868_1859234_+	Putative fluoride ion transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
AXJ54092.1\|1859230_1859584_+	Putative fluoride ion transporter CrcB	A0A2H4PQQ7	Staphylococcus_phage	4.2e-20	97.4
AXJ54093.1\|1859833_1860667_-	Glyoxal reductase	A0A2H4PQR8	Staphylococcus_phage	1.2e-158	99.6
AXJ54094.1\|1860878_1861787_-	hypothetical protein	A0A2H4PQQ8	Staphylococcus_phage	9.8e-138	99.7
AXJ54095.1\|1861911_1863105_-	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	4.3e-218	99.5
AXJ54096.1\|1863476_1865069_+	Phosphoenolpyruvate carboxykinase [ATP]	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
AXJ54097.1\|1865361_1866132_-	Prolyl oligopeptidase family protein	A0A2H4PQM6	Staphylococcus_phage	3.4e-139	97.2
AXJ54098.1\|1866112_1866592_-	Putative 8-oxo-dGTP diphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	3.0e-85	98.7
AXJ54099.1\|1866651_1866909_+	Putative membrane protein insertion efficiency factor	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
AXJ54100.1\|1866905_1867907_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	8.5e-183	96.7
AXJ54101.1\|1867911_1869390_-	2-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.4e-282	97.2
AXJ54102.1\|1869548_1870031_-	hypothetical protein	A0A2H4PQN7	Staphylococcus_phage	2.8e-75	94.5
AXJ54103.1\|1870341_1870956_+	SPBc2 prophage-derived endonuclease YokF precursor	A0A2H4PQM8	Staphylococcus_phage	3.6e-43	87.3
AXJ54104.1\|1871036_1872032_+	Telomeric repeat-binding factor 2	A0A2H4PQN2	Staphylococcus_phage	3.8e-74	97.2
AXJ54105.1\|1872107_1872734_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	4.5e-81	84.1
AXJ54106.1\|1872774_1873119_+	hypothetical protein	A0A2H4PQN6	Staphylococcus_phage	5.1e-55	94.7
AXJ54107.1\|1873216_1873789_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	3.2e-25	94.8
AXJ54108.1\|1873937_1875305_-	FRG domain protein	NA	NA	NA	NA
AXJ54109.1\|1875304_1875874_-	hypothetical protein	A0A2H4PQN8	Staphylococcus_phage	2.2e-39	54.8
AXJ54110.1\|1876066_1876513_-	hypothetical protein	NA	NA	NA	NA
AXJ54111.1\|1876594_1876819_-	hypothetical protein	NA	NA	NA	NA
AXJ54112.1\|1877457_1877901_-	hypothetical protein	NA	NA	NA	NA
AXJ54113.1\|1877900_1878344_-	hypothetical protein	NA	NA	NA	NA
AXJ54114.1\|1878343_1878664_-	hypothetical protein	NA	NA	NA	NA
AXJ54115.1\|1879310_1881731_+	Hyaluronate lyase precursor	NA	NA	NA	NA
AXJ54116.1\|1881856_1882234_-	hypothetical protein	NA	NA	NA	NA
AXJ54117.1\|1882443_1882893_-	hypothetical protein	NA	NA	NA	NA
AXJ54118.1\|1882935_1884546_+	hypothetical protein	NA	NA	NA	NA
AXJ54119.1\|1884560_1884860_+	hypothetical protein	NA	NA	NA	NA
AXJ54120.1\|1885121_1886939_-	hypothetical protein	NA	NA	NA	NA
AXJ54121.1\|1886975_1888130_-	Type I restriction modification DNA specificity domain protein	A0A2H4PQP5	Staphylococcus_phage	7.8e-39	36.3
AXJ54122.1\|1888122_1889679_-	Type I restriction enzyme EcoKI M protein	A0A2H4PQP4	Staphylococcus_phage	2.2e-286	98.6
AXJ54123.1\|1890041_1890761_-\|protease	Serine protease SplF precursor	A0A2H4PQP1	Staphylococcus_phage	1.0e-129	98.3
AXJ54124.1\|1890930_1891647_-\|protease	Serine protease SplE precursor	A0A2H4PQN5	Staphylococcus_phage	6.6e-129	97.1
AXJ54125.1\|1892692_1893409_-\|protease	Serine protease SplE precursor	A0A2H4PQN5	Staphylococcus_phage	5.5e-83	62.6
AXJ54126.1\|1893532_1894252_-\|protease	Serine protease SplC precursor	A0A2H4PQP7	Staphylococcus_phage	6.4e-124	93.7
AXJ54127.1\|1894309_1894474_-\|protease	Serine protease SplB precursor	A0A2H4PQN0	Staphylococcus_phage	5.9e-17	97.7
AXJ54128.1\|1894552_1894798_+	hypothetical protein	NA	NA	NA	NA
AXJ54129.1\|1895266_1895782_+	hypothetical protein	NA	NA	NA	NA
AXJ54130.1\|1896028_1897375_+	hypothetical protein	M1NRY5	Streptococcus_phage	2.5e-65	51.1

DBSCAN-SWA_7

1932348 : 2000892

Staphylococcus_phage(84.13%)

tRNA,protease,capsid,holin,tail,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ54163.1\|1932348_1932819_-\|tRNA	tRNA (cytidine(34)-2'-O)-methyltransferase	NA	NA	NA	NA
AXJ54164.1\|1932823_1933951_-	Epoxyqueuosine reductase	NA	NA	NA	NA
AXJ54165.1\|1934101_1934830_-	L-cystine import ATP-binding protein TcyC	G9BWD6	Planktothrix_phage	1.0e-36	42.7
AXJ54166.1\|1934816_1936274_-	Arginine transport system permease protein ArtQ	NA	NA	NA	NA
AXJ54167.1\|1936532_1937594_-	Phosphotransferase system, EIIC	NA	NA	NA	NA
AXJ54168.1\|1946422_1946869_-	Peroxide-responsive repressor PerR	NA	NA	NA	NA
AXJ54169.1\|1946965_1947925_-	Glyoxylate/hydroxypyruvate reductase B	NA	NA	NA	NA
AXJ54170.1\|1947921_1948377_-	Putative peroxiredoxin bcp	NA	NA	NA	NA
AXJ54171.1\|1948457_1949747_+	Glutamate-1-semialdehyde 2,1-aminomutase 2	NA	NA	NA	NA
AXJ54172.1\|1949988_1951134_+	Fusaric acid resistance protein family protein	NA	NA	NA	NA
AXJ54173.1\|1951324_1953061_-	Putative multidrug export ATP-binding/permease protein	W8CYL7	Bacillus_phage	1.7e-53	30.4
AXJ54174.1\|1953351_1953894_-	hypothetical protein	NA	NA	NA	NA
AXJ54175.1\|1954196_1955234_-	putative A/G-specific adenine glycosylase YfhQ	NA	NA	NA	NA
AXJ54176.1\|1955385_1956363_+	hypothetical protein	NA	NA	NA	NA
AXJ54177.1\|1956623_1957460_-	hypothetical protein	NA	NA	NA	NA
AXJ54178.1\|1957468_1958986_-	Teichoic acids export ATP-binding protein TagH	NA	NA	NA	NA
AXJ54179.1\|1959000_1959315_-	hypothetical protein	NA	NA	NA	NA
AXJ54180.1\|1959292_1960111_-	Regulatory protein RecX	NA	NA	NA	NA
AXJ54181.1\|1960371_1961181_-	Monofunctional glycosyltransferase	NA	NA	NA	NA
AXJ54182.1\|1961521_1962037_-\|protease	Putative cysteine protease YraA	NA	NA	NA	NA
AXJ54183.1\|1962166_1962328_-	hypothetical protein	NA	NA	NA	NA
AXJ54184.1\|1962824_1963562_-	hypothetical protein	A7YGY5	Staphylococcus_virus	7.5e-136	99.6
AXJ54185.1\|1963568_1964363_-	Phosphatidylinositol 3- and 4-kinase	Q4ZAU0	Staphylococcus_virus	8.3e-149	100.0
AXJ54186.1\|1964853_1965609_-	putative cell wall hydrolase LytN precursor	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
AXJ54187.1\|1965620_1965875_-\|holin	Bacteriophage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
AXJ54188.1\|1966412_1966643_-	hypothetical protein	D2JLG2	Staphylococcus_phage	1.2e-31	100.0
AXJ54189.1\|1966766_1967054_-	hypothetical protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
AXJ54190.1\|1967100_1967253_-	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
AXJ54191.1\|1967242_1971028_-	hypothetical protein	A0EX05	Staphylococcus_phage	0.0e+00	99.8
AXJ54192.1\|1971043_1972528_-\|tail	Phage tail protein	A0EX04	Staphylococcus_phage	4.5e-297	100.0
AXJ54193.1\|1972524_1977054_-	Murein DD-endopeptidase MepM	A0EX03	Staphylococcus_phage	0.0e+00	99.1
AXJ54194.1\|1977110_1977248_-	hypothetical protein	A0A2I6PDX7	Staphylococcus_phage	3.4e-18	100.0
AXJ54195.1\|1977298_1977649_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
AXJ54196.1\|1977964_1978609_-	hypothetical protein	Q6R871	Staphylococcus_virus	6.5e-120	100.0
AXJ54197.1\|1978609_1979017_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
AXJ54198.1\|1979013_1979418_-	hypothetical protein	A0A1W6JPJ1	Staphylococcus_phage	2.5e-69	100.0
AXJ54199.1\|1979414_1979777_-	hypothetical protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
AXJ54200.1\|1979760_1980045_-	hypothetical protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
AXJ54201.1\|1980034_1980319_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
AXJ54202.1\|1980338_1981559_-\|capsid	Phage capsid family protein	A0A075LYD8	Staphylococcus_phage	1.1e-229	99.5
AXJ54203.1\|1981506_1982244_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A1W6JPK0	Staphylococcus_phage	5.2e-129	99.2
AXJ54204.1\|1982227_1983415_-\|portal	Phage portal protein	A0A2I6PDI1	Staphylococcus_phage	3.0e-219	99.7
AXJ54205.1\|1983430_1985092_-	Phage Terminase	A0A075M4D3	Staphylococcus_phage	0.0e+00	100.0
AXJ54206.1\|1985088_1985433_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
AXJ54207.1\|1985562_1985862_-	HNH endonuclease	G4KNP8	Staphylococcus_phage	4.6e-52	100.0
AXJ54208.1\|1986093_1986510_-	hypothetical protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
AXJ54209.1\|1986537_1986741_-	hypothetical protein	R9QT57	Staphylococcus_phage	6.3e-29	100.0
AXJ54210.1\|1986737_1987388_-	hypothetical protein	D2JLD8	Staphylococcus_phage	8.9e-117	100.0
AXJ54211.1\|1987394_1987547_-	hypothetical protein	A0A2I6PDV2	Staphylococcus_phage	5.4e-17	100.0
AXJ54212.1\|1987546_1987699_-	Transcriptional activator RinB	A7TWB4	Staphylococcus_phage	6.4e-18	98.0
AXJ54213.1\|1987688_1987925_-	hypothetical protein	A7TWB3	Staphylococcus_phage	1.9e-37	100.0
AXJ54214.1\|1987949_1988186_-	hypothetical protein	C8CH06	Staphylococcus_phage	1.1e-35	100.0
AXJ54215.1\|1988222_1988750_-	Deoxyuridine 5'-triphosphate nucleotidohydrolase	A7TWB1	Staphylococcus_phage	7.8e-95	100.0
AXJ54216.1\|1988742_1988991_-	hypothetical protein	A0A2I6PDI5	Staphylococcus_phage	1.2e-37	98.8
AXJ54217.1\|1989031_1989280_-	hypothetical protein	S4V683	Staphylococcus_phage	3.2e-43	100.0
AXJ54218.1\|1989280_1989640_-	PVL ORF-50-like family protein	B2ZYW3	Staphylococcus_phage	1.9e-60	98.3
AXJ54219.1\|1989640_1989826_-	hypothetical protein	A0A0H4IPE3	Staphylococcus_phage	7.8e-26	95.1
AXJ54220.1\|1989830_1990235_-	hypothetical protein	Q6R835	Staphylococcus_virus	7.1e-72	99.3
AXJ54221.1\|1990244_1990466_-	hypothetical protein	Q9G021	Staphylococcus_phage	1.3e-35	100.0
AXJ54222.1\|1990478_1990640_-	hypothetical protein	D2JGK6	Staphylococcus_phage	4.5e-22	100.0
AXJ54223.1\|1990633_1991413_-	DNA replication protein DnaC	Q9G022	Staphylococcus_virus	2.4e-145	100.0
AXJ54224.1\|1991423_1992194_-	hypothetical protein	A0A1X9H0A8	Staphylococcus_phage	1.2e-120	98.8
AXJ54225.1\|1992259_1992541_+	hypothetical protein	A0A1W6JPU7	Staphylococcus_phage	2.6e-49	100.0
AXJ54226.1\|1992533_1992683_-	hypothetical protein	A7TWN0	Staphylococcus_phage	2.4e-17	98.0
AXJ54227.1\|1992679_1993351_-	hypothetical protein	Q9G025	Staphylococcus_virus	3.4e-127	98.7
AXJ54228.1\|1993363_1993915_-	hypothetical protein	Q4ZBM4	Staphylococcus_phage	3.4e-101	100.0
AXJ54229.1\|1993943_1994732_-	hypothetical protein	Q4ZBM5	Staphylococcus_phage	2.6e-142	100.0
AXJ54230.1\|1994724_1994946_-	hypothetical protein	B2ZYV2	Staphylococcus_phage	3.2e-34	100.0
AXJ54231.1\|1994955_1995216_-	hypothetical protein	Q4ZBM7	Staphylococcus_phage	1.2e-43	100.0
AXJ54232.1\|1995465_1995687_-	hypothetical protein	B2ZYU8	Staphylococcus_phage	8.7e-32	100.0
AXJ54233.1\|1995757_1995988_+	hypothetical protein	C8CGY3	Staphylococcus_phage	2.3e-35	100.0
AXJ54234.1\|1995962_1996139_-	hypothetical protein	Q4ZB00	Staphylococcus_virus	3.1e-24	100.0
AXJ54235.1\|1996163_1996904_-	Phage antirepressor protein KilAC domain protein	A0A0N7E0R7	Staphylococcus_phage	6.3e-135	100.0
AXJ54236.1\|1996963_1997446_+	hypothetical protein	A0A0N9BAX2	Staphylococcus_phage	1.1e-82	100.0
AXJ54237.1\|1997546_1997726_-	hypothetical protein	A0A0N9BAV3	Staphylococcus_phage	1.7e-25	100.0
AXJ54238.1\|1997739_1997976_-	hypothetical protein	A0A0N9BAY2	Staphylococcus_phage	1.5e-37	100.0
AXJ54239.1\|1998127_1998442_+	helix-turn-helix protein	A0A0N9BAW4	Staphylococcus_phage	9.8e-53	100.0
AXJ54240.1\|1998454_1998916_+	hypothetical protein	Q4ZBN7	Staphylococcus_phage	4.6e-83	99.3
AXJ54241.1\|1998936_1999428_+	hypothetical protein	Q4ZBN8	Staphylococcus_phage	7.5e-84	100.0
AXJ54242.1\|1999431_1999539_+	hypothetical protein	Q4ZBN9	Staphylococcus_phage	2.6e-10	100.0
AXJ54243.1\|1999553_1999733_-	hypothetical protein	Q4ZBP0	Staphylococcus_phage	3.7e-25	100.0
AXJ54244.1\|1999845_2000892_+	Tyrosine recombinase XerC	Q4ZE08	Staphylococcus_virus	4.2e-201	100.0

DBSCAN-SWA_8

2078076 : 2092410

Staphylococcus_phage(68.42%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ54314.1\|2078076_2078304_-	hypothetical protein	A0A2H4JAH5	uncultured_Caudovirales_phage	1.9e-13	47.4
AXJ54315.1\|2078722_2079427_+	Toxic shock syndrome toxin-1 precursor	NA	NA	NA	NA
AXJ54316.1\|2079581_2080151_-	Terminase small subunit	Q4ZE85	Staphylococcus_phage	3.5e-101	98.4
AXJ54317.1\|2080147_2080489_-	hypothetical protein	A0A1W6JQM3	Staphylococcus_phage	1.7e-58	100.0
AXJ54318.1\|2080491_2081019_-	hypothetical protein	A0A1W6JQH7	Staphylococcus_phage	3.5e-87	97.1
AXJ54319.1\|2081069_2081288_-	hypothetical protein	NA	NA	NA	NA
AXJ54320.1\|2081305_2081884_-	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	1.4e-28	38.4
AXJ54321.1\|2081895_2082237_-	hypothetical protein	Q4ZE66	Staphylococcus_phage	7.1e-57	98.2
AXJ54322.1\|2082780_2083404_-	hypothetical protein	Q4ZE67	Staphylococcus_phage	5.0e-109	94.7
AXJ54323.1\|2083400_2083781_-	hypothetical protein	Q4ZE71	Staphylococcus_phage	6.9e-69	100.0
AXJ54324.1\|2084092_2085802_-	hypothetical protein	Q4ZE73	Staphylococcus_phage	0.0e+00	99.8
AXJ54325.1\|2085815_2086685_-	hypothetical protein	Q4ZE74	Staphylococcus_phage	6.0e-169	99.3
AXJ54326.1\|2086748_2087066_-	hypothetical protein	A0A1W6JQH0	Staphylococcus_phage	1.6e-18	58.2
AXJ54327.1\|2087066_2087450_-	hypothetical protein	A0A1W6JQI7	Staphylococcus_phage	9.7e-63	96.1
AXJ54328.1\|2087451_2087655_-	hypothetical protein	A0A1W6JQF4	Staphylococcus_phage	7.5e-30	97.0
AXJ54329.1\|2087639_2087795_-	hypothetical protein	NA	NA	NA	NA
AXJ54330.1\|2087791_2088109_-	Helix-turn-helix domain protein	A0A1W6JQE0	Staphylococcus_phage	9.2e-51	98.1
AXJ54331.1\|2088113_2088332_-	Helix-turn-helix domain protein	A0A2H4JB11	uncultured_Caudovirales_phage	1.3e-19	66.7
AXJ54332.1\|2088504_2089179_+	Helix-turn-helix domain protein	A0A2H4JGT9	uncultured_Caudovirales_phage	1.6e-39	45.8
AXJ54333.1\|2089192_2090365_+\|transposase	transposase	A0A1W6JQD3	Staphylococcus_phage	3.5e-220	98.2
AXJ54334.1\|2090433_2092050_-	60 kDa chaperonin	A0A240F779	uncultured_virus	2.6e-157	54.7
AXJ54335.1\|2092125_2092410_-	10 kDa chaperonin	A0A221S386	uncultured_virus	4.7e-14	46.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP022900

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

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Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection