CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP022896	Staphylococcus aureus strain 277 chromosome, complete genome	7 crisprs	csa3,cas3,DEDDh,DinG,WYL	5	0	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP022896_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022896_1

799159-799243

Unclear

Consensus_repeat	Method
CACCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of CP022896_1

>merge|CP022896|1|799159-799243|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCACACCCCAACTTGCATTGCCTGTAGAA

>CP022896|1|1|799159-799243|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCA
CACCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP022896.1\|AXJ43005.1\|800753_801404_+\|5'-deoxynucleotidase-YfbR	unknown	unknown	gnl\|CDD\|378993
CP022896.1\|AXJ43008.1\|803898_806745_+\|UvrABC-system-protein-A	unknown	unknown	gnl\|CDD\|234734
CP022896.1\|AXJ43006.1\|801400_801637_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227234
CP022896.1\|AXJ43009.1\|807355_808288_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
CP022896.1\|AXJ42999.1\|792230_793313_+\|UvrABC-system-protein-B	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|226583
CP022896.1\|AXJ43007.1\|801905_803891_+\|UvrABC-system-protein-B	unknown	unknown	gnl\|CDD\|235395
CP022896.1\|AXJ43012.1\|809636_811076_+\|Tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
CP022896.1\|AXJ43001.1\|794040_794613_+\|Putative-sigma-54-modulation-protein	unknown	unknown	gnl\|CDD\|224461
CP022896.1\|AXJ42998.1\|791000_791867_+\|DegV-domain-containing-protein	unknown	unknown	gnl\|CDD\|273257
CP022896.1\|AXJ43002.1\|795026_797558_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
CP022896.1\|AXJ42995.1\|787608_788679_-\|Diguanylate-cyclase-DosC	unknown	unknown	gnl\|CDD\|143635
CP022896.1\|AXJ42997.1\|790215_790857_-\|IMPACT-family-member-YigZ	unknown	unknown	gnl\|CDD\|224653
CP022896.1\|AXJ43010.1\|808293_809136_+\|Prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
CP022896.1\|AXJ42996.1\|788996_790052_+\|putative-undecaprenyl-phosphate-N-acetylglucosaminyl-1-phosphate-transferase	unknown	unknown	gnl\|CDD\|133463
CP022896.1\|AXJ43000.1\|793305_793980_+\|DNA-utilization-protein-GntX	unknown	unknown	gnl\|CDD\|223970
CP022896.1\|AXJ43011.1\|809143_809629_+\|Maltose-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100053
CP022896.1\|AXJ42994.1\|786651_787413_-\|Inner-membrane-protein-YjjP	unknown	unknown	gnl\|CDD\|225514
CP022896.1\|AXJ43003.1\|797990_798983_+\|Peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
CP022896.1\|AXJ43013.1\|811142_812078_+\|Thioredoxin-reductase	unknown	unknown	gnl\|CDD\|273540
CP022896.1\|AXJ43004.1\|799751_800591_+\|Secretory-antigen-SsaA-precursor	unknown	unknown	gnl\|CDD\|226451

Protein	Function_ID	Function_description	E-value
CP022896.1\|AXJ43005.1\|800753_801404_+\|5'-deoxynucleotidase-YfbR	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
CP022896.1\|AXJ43008.1\|803898_806745_+\|UvrABC-system-protein-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP022896.1\|AXJ43006.1\|801400_801637_+\|hypothetical-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
CP022896.1\|AXJ43009.1\|807355_808288_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
CP022896.1\|AXJ42999.1\|792230_793313_+\|UvrABC-system-protein-B	gnl\|CDD\|226583	COG4098, comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair].	1.30855e-179
CP022896.1\|AXJ43007.1\|801905_803891_+\|UvrABC-system-protein-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP022896.1\|AXJ43012.1\|809636_811076_+\|Tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	7.77476e-06
CP022896.1\|AXJ43001.1\|794040_794613_+\|Putative-sigma-54-modulation-protein	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
CP022896.1\|AXJ42998.1\|791000_791867_+\|DegV-domain-containing-protein	gnl\|CDD\|273257	TIGR00762, DegV, EDD domain protein, DegV family. This family of proteins is related to DegV of Bacillus subtilis and includes paralogous sets in several species (B. subtilis, Deinococcus radiodurans, Mycoplasma pneumoniae) that are closer in percent identity to each than to most homologs from other species. This suggests both recent paralogy and diversity of function. DegV itself is encoded immediately downstream of DegU, a transcriptional regulator of degradation, but is itself uncharacterized. Crystallography suggested a lipid-binding site, while comparison of the crystal structure to dihydroxyacetone kinase and to a mannose transporter EIIA domain suggests a conserved domain, EDD, with phosphotransferase activity. [Unknown function, General].	9.17692e-120
CP022896.1\|AXJ43002.1\|795026_797558_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
CP022896.1\|AXJ42995.1\|787608_788679_-\|Diguanylate-cyclase-DosC	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.2404e-45
CP022896.1\|AXJ42997.1\|790215_790857_-\|IMPACT-family-member-YigZ	gnl\|CDD\|224653	COG1739, COG1739, Uncharacterized conserved protein [Function unknown].	7.46066e-72
CP022896.1\|AXJ43010.1\|808293_809136_+\|Prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	6.12313e-120
CP022896.1\|AXJ42996.1\|788996_790052_+\|putative-undecaprenyl-phosphate-N-acetylglucosaminyl-1-phosphate-transferase	gnl\|CDD\|133463	cd06853, GT_WecA_like, This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate molecule and N-acetylglucosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylglucosamine precursor. WecA participates in the biosynthesis of O antigen LPS in many enteric bacteria and is also involved in the biosynthesis of enterobacterial common antigen. A conserved short sequence motif and a conserved arginine at a cytosolic loop of this integral membrane protein were shown to be critical in recognition of substrate UDP-N-acetylglucosamine.	2.69988e-87
CP022896.1\|AXJ43000.1\|793305_793980_+\|DNA-utilization-protein-GntX	gnl\|CDD\|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	1.20522e-50
CP022896.1\|AXJ43011.1\|809143_809629_+\|Maltose-O-acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	7.57447e-30
CP022896.1\|AXJ42994.1\|786651_787413_-\|Inner-membrane-protein-YjjP	gnl\|CDD\|225514	COG2966, COG2966, Uncharacterized conserved protein [Function unknown].	1.53065e-80
CP022896.1\|AXJ43003.1\|797990_798983_+\|Peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
CP022896.1\|AXJ43013.1\|811142_812078_+\|Thioredoxin-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	5.52692e-153
CP022896.1\|AXJ43004.1\|799751_800591_+\|Secretory-antigen-SsaA-precursor	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	2.39887e-42

>CP022896.1|AXJ43003.1|797990_798983_+|Peptide-chain-release-factor-2
MAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDGEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>CP022896.1|AXJ43002.1|795026_797558_+|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKSVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>CP022896.1|AXJ43001.1|794040_794613_+|Putative-sigma-54-modulation-protein
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>CP022896.1|AXJ43000.1|793305_793980_+|DNA-utilization-protein-GntX
MNNCLSCGAKLYENITIYNLFKKPNRLCDRCKENWDNIKLDIKARRCSRCLKYLDQNEAYCLDCKFLSAHFNLMEQLYCQFQYDGLMKEMIHQYKFSKDYYLCELLAHLIEIPQTSYDYIVPIPSSPAHDLSRTFNPVEAVLKAKGIRFDKILKMSNRPKQSHLTKKERLADENPFIIDTELDLNGKEILLVDDIYTTGLTIHRAGCKLYAKNIRKFKVFAFAR
>CP022896.1|AXJ42999.1|792230_793313_+|UvrABC-system-protein-B
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRMRQTILLYAVTGAGKTEMMFQGIQYARRQGDNIAIVSPRVDVVVEISKRIKDAFLNEDIDILHQQSSQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKSLQQALKSSSKVEHATIYMTATPPKQLLSEIPLENIIKLPARFHKKSLPVPKYRYFKLNNNKIQKMLYRILQDQINNQRYTLVFFNNIETMIKTFSIYKQKITKLTYVHSEDVFRFEKVEQLRNGQYDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKLECPTGKVLFFHEGVSMNMIQAKKEIQKMNKLALKRGWIDE
>CP022896.1|AXJ42998.1|791000_791867_+|DegV-domain-containing-protein
MKIAVMTDSTSYLSQDLIDKYNIQIAPLSVTFDDGKNFTESNEIAIEEFYNKMASSQTIPTTSQPAIGEWITKYEMLRDQGYTDIIVICLSSGISGSYQSSYQAGEMVEGVNVHAFDSKLAAMIEGCYVLRAIEMVEEGYEPQQIIDDLTNMREHTGAYLIVDDLKNLQKSGRITGAQAWVGTLLKMKPVLKFEDGKIIPEEKVRTKKRAIQTLEKKVLDIVKDFEEVTLFVINGDHFEDGQALYKKLQDDCPSAYQVAYSEFGPVVAAHLGSGGLGLGYVGRKIRLT
>CP022896.1|AXJ42997.1|790215_790857_-|IMPACT-family-member-YigZ
MTQNIITVKKEHIIENVISKSRFIAHIKPVQNEDEAKAFIAAIKKEHKDATHNCSAYTIGPEMNIQKANDDGEPTGTAGVPMLDILKKLDVHNACVVVTRYFGGIKLGGGGLIRAYSGAVRDVIYDIGRVELREAVPCIVTLNYDQTGKFEYELASTHFMLRNQTYTDKVSYYIDVVKSDYEAFINFLNQMTAGNFDLTEETPKQLPFDIPTE
>CP022896.1|AXJ42996.1|788996_790052_+|putative-undecaprenyl-phosphate-N-acetylglucosaminyl-1-phosphate-transferase
MVTLLLVAVTMIVSLTITPIVIAISKRLNLVDKPNFRKVHTKPISVMGGTVILFSFLIGIWIGHPIETEIKPLIIGAIIMYVLGLVDDIYDLKPYIKLAGQIAAALVVAFYGVTIDFISLPMGTTIHFGFLSIPITVIWIVAITNAINLIDGLDGLASGVSAIGLITIGFIAILQANIFITMICCVLLGSLIGFLFYNFHPAKIFLGDSGALMIGFIIGFLSLLGFKNITIIALFFPIVILAVPFIDTLFAMIRRVKKGQHIMQADKSHLHHKLLALGYTHRQTVLLIYSISILFSLSSIILYVSPPLGVVLMFVLIIFSIELIVEFTGLIDNNYRPILNLISRKSSHKEE
>CP022896.1|AXJ42995.1|787608_788679_-|Diguanylate-cyclase-DosC
MFEAFIYNISVIVAGIYLFHRLQYSENKRMVFSKAYVTVLMTIVSLLLSVYPIPYREDYLIHLTFVPLLFLGRFTNMVYTLSATVIVAIVEIVVFNNSIMYGVTLIVIAAVTSAIGPFLKQNDVLSLLILNVVTIIILFGVALVSPIYTLSEVIILIPISLIITLASAITFVDIWHFFSLVNRYENEDKYDYLTGLGNVKEFDRHLNEISRKAEKEHQSIALLLIDIDGFKDVNDTYSHKSGDAVLKQMSQLLKNYVPNQFKIFRNGGEEFSVVIHNYSLDQSVKLAENIRSGVEKSSFHLPNKEVIKLSVSIGVGYLTDDDPKSQRKVFKDADDMVHVAKNQGRNKVMFNPIINL
>CP022896.1|AXJ42994.1|786651_787413_-|Inner-membrane-protein-YjjP
MPDSITIIDENKVIDVVLIAGRILLESGAETYRVEDTMNRIAHSYGLHNTYSFVSSTAIIFSLNDRTSTRLIRVQERTTDLEKIALTNSLSRKISNKELTIDEAKSEFIHLQHASLQYSFLTNFFAAAIACGFFLFMFGGVASDCWIAVIAGGSAFLTFSFVQRYIQIKFFSEFVAAAVVISIAATFTKLGIATNQDIITIASVMPLVPGILITNAIRDLLAGELLAGMSRGVEAALTAFAIGAGVAIVLLII
>CP022896.1|AXJ43004.1|799751_800591_+|Secretory-antigen-SsaA-precursor
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKTVKSLVRKASQAKKVVQQPVQQASKKVVVKQAPKQTVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>CP022896.1|AXJ43005.1|800753_801404_+|5'-deoxynucleotidase-YfbR
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>CP022896.1|AXJ43006.1|801400_801637_+|hypothetical-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>CP022896.1|AXJ43007.1|801905_803891_+|UvrABC-system-protein-B
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>CP022896.1|AXJ43008.1|803898_806745_+|UvrABC-system-protein-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNINLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>CP022896.1|AXJ43009.1|807355_808288_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>CP022896.1|AXJ43010.1|808293_809136_+|Prolipoprotein-diacylglyceryl-transferase
MGGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPGEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTRKVK
>CP022896.1|AXJ43011.1|809143_809629_+|Maltose-O-acetyltransferase
MRKFLSKEYHRTNPLWHVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQILNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP022896.1|AXJ43012.1|809636_811076_+|Tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMANQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLKEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP022896.1|AXJ43013.1|811142_812078_+|Thioredoxin-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSAPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA

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Crispr_ID: CP022896_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022896_2

906712-906797

Orphan

Consensus_repeat	Method
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022896_2

>merge|CP022896|2|906712-906797|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGTGGAAAGCCAGCTTACAATAATGTGCAAGTTGG

>CP022896|2|2|906712-906797|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CGGGGCCCCAACACAGAAGCTGGTGG
AAAGCCAGCTTACAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
CP022896.1\|AXJ43102.1\|897431_897860_-\|Na(+)/H(+)-antiporter-subunit-B1	unknown	unknown	gnl\|CDD\|183602
CP022896.1\|AXJ43101.1\|897090_897432_-\|Na(+)/H(+)-antiporter-subunit-C1	unknown	unknown	gnl\|CDD\|181497
CP022896.1\|AXJ43109.1\|905316_906561_+\|NAD-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
CP022896.1\|AXJ43103.1\|897852_900258_-\|Na(+)/H(+)-antiporter-subunit-A1	unknown	unknown	gnl\|CDD\|237155
CP022896.1\|AXJ43116.1\|913828_914404_+\|Signal-peptidase-IB	unknown	unknown	gnl\|CDD\|274044
CP022896.1\|AXJ43107.1\|902582_903710_+\|NADH-oxidase	unknown	unknown	gnl\|CDD\|240086
CP022896.1\|AXJ43104.1\|900388_900772_-\|Kinase-associated-lipoprotein-B-precursor	unknown	unknown	gnl\|CDD\|378054
CP022896.1\|AXJ43106.1\|901843_902221_+\|General-stress-protein-13	unknown	unknown	gnl\|CDD\|224023
CP022896.1\|AXJ43105.1\|900835_901429_+\|Putative-peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|238908
CP022896.1\|AXJ43119.1\|921859_922762_+\|Ureidoglycolate-lyase	unknown	unknown	gnl\|CDD\|223257
CP022896.1\|AXJ43117.1\|914563_918040_+\|ATP-dependent-helicase/deoxyribonuclease-subunit-B	unknown	unknown	gnl\|CDD\|213736
CP022896.1\|AXJ43113.1\|911051_912383_+\|Glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
CP022896.1\|AXJ43110.1\|906955_907885_-\|putative-glycerophosphoryl-diester-phosphodiesterase-1	unknown	unknown	gnl\|CDD\|176543
CP022896.1\|AXJ43100.1\|895601_897098_-\|Na(+)/H(+)-antiporter-subunit-D1	unknown	unknown	gnl\|CDD\|181085
CP022896.1\|AXJ43114.1\|912708_913284_+\|TVP38/TMEM64-family-inner-membrane-protein-YdjZ	unknown	unknown	gnl\|CDD\|223475
CP022896.1\|AXJ43115.1\|913288_913813_+\|Signal-peptidase-IB	unknown	unknown	gnl\|CDD\|274044
CP022896.1\|AXJ43108.1\|904017_905208_+\|Ornithine-aminotransferase-2	unknown	unknown	gnl\|CDD\|179736
CP022896.1\|AXJ43118.1\|918040_921694_+\|ATP-dependent-helicase/nuclease-subunit-A	unknown	unknown	gnl\|CDD\|274299
CP022896.1\|AXJ43112.1\|909495_910701_-\|Argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
CP022896.1\|AXJ43111.1\|908126_909506_-\|Argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143

Protein	Function_ID	Function_description	E-value
CP022896.1\|AXJ43102.1\|897431_897860_-\|Na(+)/H(+)-antiporter-subunit-B1	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
CP022896.1\|AXJ43101.1\|897090_897432_-\|Na(+)/H(+)-antiporter-subunit-C1	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	9.82501e-64
CP022896.1\|AXJ43109.1\|905316_906561_+\|NAD-specific-glutamate-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
CP022896.1\|AXJ43103.1\|897852_900258_-\|Na(+)/H(+)-antiporter-subunit-A1	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
CP022896.1\|AXJ43116.1\|913828_914404_+\|Signal-peptidase-IB	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.63465e-53
CP022896.1\|AXJ43107.1\|902582_903710_+\|NADH-oxidase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
CP022896.1\|AXJ43104.1\|900388_900772_-\|Kinase-associated-lipoprotein-B-precursor	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	8.96507e-53
CP022896.1\|AXJ43106.1\|901843_902221_+\|General-stress-protein-13	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
CP022896.1\|AXJ43105.1\|900835_901429_+\|Putative-peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
CP022896.1\|AXJ43119.1\|921859_922762_+\|Ureidoglycolate-lyase	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	6.54658e-87
CP022896.1\|AXJ43117.1\|914563_918040_+\|ATP-dependent-helicase/deoxyribonuclease-subunit-B	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
CP022896.1\|AXJ43113.1\|911051_912383_+\|Glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
CP022896.1\|AXJ43110.1\|906955_907885_-\|putative-glycerophosphoryl-diester-phosphodiesterase-1	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	8.83368e-151
CP022896.1\|AXJ43100.1\|895601_897098_-\|Na(+)/H(+)-antiporter-subunit-D1	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
CP022896.1\|AXJ43114.1\|912708_913284_+\|TVP38/TMEM64-family-inner-membrane-protein-YdjZ	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	4.0006e-40
CP022896.1\|AXJ43115.1\|913288_913813_+\|Signal-peptidase-IB	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.75286e-49
CP022896.1\|AXJ43108.1\|904017_905208_+\|Ornithine-aminotransferase-2	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
CP022896.1\|AXJ43118.1\|918040_921694_+\|ATP-dependent-helicase/nuclease-subunit-A	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
CP022896.1\|AXJ43112.1\|909495_910701_-\|Argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
CP022896.1\|AXJ43111.1\|908126_909506_-\|Argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0

>CP022896.1|AXJ43109.1|905316_906561_+|NAD-specific-glutamate-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>CP022896.1|AXJ43108.1|904017_905208_+|Ornithine-aminotransferase-2
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINKNTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFARDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>CP022896.1|AXJ43107.1|902582_903710_+|NADH-oxidase
MKSKYEPLFDKVVLPNGVELRNRFVLAPLTHISSNDDGTISDIELPYIEKRSQDVGITSNAASNVSDVGKAFPGQPSIAHDSDIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPIAVIEEVLKSKEVYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATAREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADDALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>CP022896.1|AXJ43106.1|901843_902221_+|General-stress-protein-13
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>CP022896.1|AXJ43105.1|900835_901429_+|Putative-peptidyl-prolyl-cis-trans-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>CP022896.1|AXJ43104.1|900388_900772_-|Kinase-associated-lipoprotein-B-precursor
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHERKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>CP022896.1|AXJ43103.1|897852_900258_-|Na(+)/H(+)-antiporter-subunit-A1
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWIWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASKANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTVFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>CP022896.1|AXJ43102.1|897431_897860_-|Na(+)/H(+)-antiporter-subunit-B1
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>CP022896.1|AXJ43101.1|897090_897432_-|Na(+)/H(+)-antiporter-subunit-C1
MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>CP022896.1|AXJ43100.1|895601_897098_-|Na(+)/H(+)-antiporter-subunit-D1
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPLRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAITRTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK
>CP022896.1|AXJ43110.1|906955_907885_-|putative-glycerophosphoryl-diester-phosphodiesterase-1
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNHIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDENVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNKNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>CP022896.1|AXJ43111.1|908126_909506_-|Argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLSTYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>CP022896.1|AXJ43112.1|909495_910701_-|Argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMRAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>CP022896.1|AXJ43113.1|911051_912383_+|Glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>CP022896.1|AXJ43114.1|912708_913284_+|TVP38/TMEM64-family-inner-membrane-protein-YdjZ
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVDTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLIVFWIVGKKLEQHFMGSKKE
>CP022896.1|AXJ43115.1|913288_913813_+|Signal-peptidase-IB
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKKLDGDIIPPNNFVVLNDHDNNQHDSRQFGLIDKKDIIGNISLRYYPFSKWTIQFKS
>CP022896.1|AXJ43116.1|913828_914404_+|Signal-peptidase-IB
MKKELLEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKYNFNPENTKN
>CP022896.1|AXJ43117.1|914563_918040_+|ATP-dependent-helicase/deoxyribonuclease-subunit-B
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLESFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDALQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEISNELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQINPMLRLLKTDVLTTSYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAATVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGNVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDHLSQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>CP022896.1|AXJ43118.1|918040_921694_+|ATP-dependent-helicase/nuclease-subunit-A
MTIPEKPQGVIWTDAQWQSIYETGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDISYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFHEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTLDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVRYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVFDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYKAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIIYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADTKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>CP022896.1|AXJ43119.1|921859_922762_+|Ureidoglycolate-lyase
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVERLYVFTKAASSLTGDNAKIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK

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Crispr_ID: CP022896_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022896_3

1933780-1933907

Orphan

Consensus_repeat	Method
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022896_3

>merge|CP022896|3|1933780-1933907|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTCATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTATTAAATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

>CP022896|3|3|1933780-1933907|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	ATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTATTA
AATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

Protein	Signature genes	Signature genes Name	Protein_function
CP022896.1\|AXJ44008.1\|1942456_1943416_-\|Glyoxylate/hydroxypyruvate-reductase-B	unknown	unknown	gnl\|CDD\|240632
CP022896.1\|AXJ43999.1\|1925939_1926335_-\|hypothetical-protein	unknown	unknown	unknown
CP022896.1\|AXJ44003.1\|1928345_1929473_-\|Epoxyqueuosine-reductase	unknown	unknown	gnl\|CDD\|272993
CP022896.1\|AXJ44001.1\|1927112_1927712_-\|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|223440
CP022896.1\|AXJ44014.1\|1949687_1950725_-\|putative-A/G-specific-adenine-glycosylase-YfhQ	unknown	unknown	gnl\|CDD\|224115
CP022896.1\|AXJ44006.1\|1932054_1933116_-\|Phosphotransferase-system,-EIIC	unknown	unknown	gnl\|CDD\|226167
CP022896.1\|AXJ44009.1\|1943412_1943868_-\|Putative-peroxiredoxin-bcp	unknown	unknown	gnl\|CDD\|224146
CP022896.1\|AXJ44004.1\|1929623_1930352_-\|L-cystine-import-ATP-binding-protein-TcyC	unknown	unknown	gnl\|CDD\|224051
CP022896.1\|AXJ44016.1\|1952114_1952951_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224596
CP022896.1\|AXJ44015.1\|1950876_1951854_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224899
CP022896.1\|AXJ44011.1\|1945479_1946625_+\|Fusaric-acid-resistance-protein-family-protein	unknown	unknown	gnl\|CDD\|226614
CP022896.1\|AXJ44012.1\|1946815_1948552_-\|Putative-multidrug-export-ATP-binding/permease-protein	unknown	unknown	gnl\|CDD\|224055
CP022896.1\|AXJ44005.1\|1930338_1931796_-\|Arginine-transport-system-permease-protein-ArtQ	unknown	unknown	gnl\|CDD\|223836
CP022896.1\|AXJ44002.1\|1927870_1928341_-\|tRNA-(cytidine(34)-2'-O)-methyltransferase	unknown	unknown	gnl\|CDD\|223297
CP022896.1\|AXJ43998.1\|1924358_1925744_-\|Fumarate-hydratase-class-II	unknown	unknown	gnl\|CDD\|234779
CP022896.1\|AXJ44000.1\|1926935_1927088_-\|hypothetical-protein	unknown	unknown	unknown
CP022896.1\|AXJ43997.1\|1923081_1923903_+\|Ribosomal-large-subunit-pseudouridine-synthase-D	unknown	unknown	gnl\|CDD\|223638
CP022896.1\|AXJ44007.1\|1941913_1942360_-\|Peroxide-responsive-repressor-PerR	unknown	unknown	gnl\|CDD\|223806
CP022896.1\|AXJ44013.1\|1948842_1949385_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184219
CP022896.1\|AXJ44010.1\|1943948_1945238_+\|Glutamate-1-semialdehyde-2,1-aminomutase-2	unknown	unknown	gnl\|CDD\|183493

Protein	Function_ID	Function_description	E-value
CP022896.1\|AXJ44008.1\|1942456_1943416_-\|Glyoxylate/hydroxypyruvate-reductase-B	gnl\|CDD\|240632	cd12155, PGDH_1, Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family. Phosphoglycerate Dehydrogenase (PGDH) catalyzes the NAD-dependent conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first step in serine biosynthesis. Over-expression of PGDH has been implicated as supporting proliferation of certain breast cancers, while PGDH deficiency is linked to defects in mammalian central nervous system development. PGDH is a member of the 2-hydroxyacid dehydrogenase family, enzymes that catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	9.10866e-135
CP022896.1\|AXJ44005.1\|1930338_1931796_-\|Arginine-transport-system-permease-protein-ArtQ	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.55367e-98
CP022896.1\|AXJ44003.1\|1928345_1929473_-\|Epoxyqueuosine-reductase	gnl\|CDD\|272993	TIGR00276, iron-sulfur_cluster-binding_protein, epoxyqueuosine reductase. This model was rebuilt to exclude archaeal homologs, now that there is new information that bacterial members are epoxyqueuosine reductase, QueG, involved in queuosine biosynthesis for tRNA maturation. [Protein synthesis, tRNA and rRNA base modification].	5.66267e-179
CP022896.1\|AXJ44001.1\|1927112_1927712_-\|glucosamine-6-phosphate-deaminase	gnl\|CDD\|223440	COG0363, NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism].	9.77274e-11
CP022896.1\|AXJ44014.1\|1949687_1950725_-\|putative-A/G-specific-adenine-glycosylase-YfhQ	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	4.67816e-157
CP022896.1\|AXJ44006.1\|1932054_1933116_-\|Phosphotransferase-system,-EIIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	1.65132e-122
CP022896.1\|AXJ44009.1\|1943412_1943868_-\|Putative-peroxiredoxin-bcp	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	1.5916e-68
CP022896.1\|AXJ44004.1\|1929623_1930352_-\|L-cystine-import-ATP-binding-protein-TcyC	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.22702e-152
CP022896.1\|AXJ44016.1\|1952114_1952951_-\|hypothetical-protein	gnl\|CDD\|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	0.000164936
CP022896.1\|AXJ44011.1\|1945479_1946625_+\|Fusaric-acid-resistance-protein-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	1.08084e-85
CP022896.1\|AXJ44012.1\|1946815_1948552_-\|Putative-multidrug-export-ATP-binding/permease-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
CP022896.1\|AXJ44002.1\|1927870_1928341_-\|tRNA-(cytidine(34)-2'-O)-methyltransferase	gnl\|CDD\|223297	COG0219, CspR, Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis].	1.70324e-88
CP022896.1\|AXJ43998.1\|1924358_1925744_-\|Fumarate-hydratase-class-II	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
CP022896.1\|AXJ44015.1\|1950876_1951854_+\|hypothetical-protein	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	1.21408e-39
CP022896.1\|AXJ43997.1\|1923081_1923903_+\|Ribosomal-large-subunit-pseudouridine-synthase-D	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	3.57209e-78
CP022896.1\|AXJ44007.1\|1941913_1942360_-\|Peroxide-responsive-repressor-PerR	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	6.09298e-56
CP022896.1\|AXJ44013.1\|1948842_1949385_-\|hypothetical-protein	gnl\|CDD\|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	1.0244e-125
CP022896.1\|AXJ44010.1\|1943948_1945238_+\|Glutamate-1-semialdehyde-2,1-aminomutase-2	gnl\|CDD\|183493	PRK12389, PRK12389, glutamate-1-semialdehyde aminotransferase; Provisional.	0

>CP022896.1|AXJ44006.1|1932054_1933116_-|Phosphotransferase-system,-EIIC
MSNAKNADNKQFFSKILNSIGAGVVIALVPNALLGEVLKIFKSGNEILELTYQLVILIQSFMAFIIGVLAAHQFKFNGAGAAIVGTSAMIGSGAVVYSNNSFMLKGIGDIINTSLVVIIACLIYMVLQNKLGSFELIILPVLVPIVSGGIGLITLPYIRKITQAIGNVIHSFTDLNPLLMSILISVAFSLLMVTPISLVAIATAISLNGLGSGAANLGIVAACVTFLFGSLRVNSIGVNAVLLIGAAKMMIPVYLKNLIISIPLTINGIITGIIAYVLQVKGTPLSAGFGYTGLVGPINAFNRMSGDPTMNIILLALGYFVIPFVSAFIVHELCKKFIPIYSNDIYKFEVPKQ
>CP022896.1|AXJ44005.1|1930338_1931796_-|Arginine-transport-system-permease-protein-ArtQ
MKCLIRFILVLGLLISSAMVYINPAAYAEQDQKWEKIKERGELRVGLSADYAPMEFEHTVNGKTEYAGVDIDLAKKIAKDNNLKLKIVNMSFDSLLGALKTGKIDIIISGMTSTPERKKQVDFSDSYMMTKNIMLVKKDKVNDYKDIKDFNNKKVGAQKGTEQEKIAQTEIENASITSLSRLPDVILALKSGKVEGVVVEKPVAEAYLKQNPKLGISNVKFNEEEKDTVIAVPKDSPKLLSQINKTIKEVKDKGLIDKYMTNAANAMNDDSGFISKYGSFFLKGIKITILISLIGVALGSILGAFVALMKLSKIKIISWIASIYIEILRGTPMLVQVFIVFFGITAALGLDISALVCGTIALVINSSAYIAEIIRAGINAVDKGQMEAARSLGLNYRQTMKSVIMPQAIKNILPALGNEFVTLIKESSIVSTIGVGEIMFNAQVVQGISFDPFTPLLVAAALYFVLTFVLTRIMNMIEGRLNASD
>CP022896.1|AXJ44004.1|1929623_1930352_-|L-cystine-import-ATP-binding-protein-TcyC
MPVIKINNLNKVFGDNEVLKDINLEINQGEVVAIIGPSGSGKSTLLRCMNLLEVPTKGQVIFEGNDLTEKGTQVDKLRQKMGMVFQNFNLFPHKKVVDNIILAPKLLKKDNNDELHKEALSLLDKVGLKEKADVYPNQLSGGQKQRVAIARALAMHPDVILFDEPTSALDPEVVGDVLKVMKDLAKEGMTMVVVTHEMGFAKDVSDKVIFMADGVVVESGTPVEIFEQPQHERTQNFLARVL
>CP022896.1|AXJ44003.1|1928345_1929473_-|Epoxyqueuosine-reductase
MDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANGYASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWGQDYHTIMRKRLDMLAAFIESKVPDVEIKSMVDTGVLSDRAVAERAGLGFVGRNDFVINPKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFLTQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLRMSNKEFKQTYGHLAGAWRGKKPIQRNAILALAHFNEVDAIPELKKVATTDERPMIRATAYWAIGQILGEEARDFINANYDQEDAEVQNEMIKGLDTRRE
>CP022896.1|AXJ44002.1|1927870_1928341_-|tRNA-(cytidine(34)-2'-O)-methyltransferase
MTNHIVLYQPEIPANTGNIARTCAGTNTHLHLIKPLGFRTDDKMLKRAGLDYWEFVNITYHDSIEAFFEATNGEYYLLTKFGKKTYSDFDFSNHDKDFYFIFGKETTGLPDWVKEKYQDTALRIPMSEHIRSLNLSNTAALLIYEALRQQDFPGLN
>CP022896.1|AXJ44001.1|1927112_1927712_-|glucosamine-6-phosphate-deaminase
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNIEKHAVDFSQINILDYDDKKSYFEALGVPAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGKTSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
>CP022896.1|AXJ44000.1|1926935_1927088_-|hypothetical-protein
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
>CP022896.1|AXJ43999.1|1925939_1926335_-|hypothetical-protein
MLGKYWIQLLIATVIISLISIKAFPLAIGALYLPIIFKVIKLQLNLSKGLIDDVNAQTFIKSNQSGIVISVICCLLITGILYYTLDGFYASLTGVLGTLVALNPYTTIVSAVLYILTAIATVEATKTKYRN
>CP022896.1|AXJ43998.1|1924358_1925744_-|Fumarate-hydratase-class-II
MSVRIEHDTFGEIEVPADKYWGAQTERSKRNFPVGKERMPIEVVYGFAQLKRAAALANFDLGKLSEAKKDAIVYACDQILSGELDEHFPLVVWQTGSGTQSNMNVNEVVSYVANMYLKDHHSDESIHPNDDVNKSQSSNDTFPTAMHVALYQEVETKLEPALKLLRNTLKEKEDKFDSIIKIGRTHLQDATPIKLGQEISGWRYMLDRCETMLSESKKHILNLAIGGTAVGTGINAHPEFGDKVAQYISENTGYPFVSSENKFHALTAHDEVVQLHGTLKALAGDLMKIANDVRWLASGPRAGLAEISIPENEPGSSIMPGKVNPTQCEMLTMVAVQVMGNDTVVGFASSQGNFELNVYKPVIMHNTLQSIYLLADGMETFNNNCAVGIEPIEENIDNYLNQSLMLVTALNPHIGYEKAAQIAKKAHKEGLTLKESAIQTGYVTEEQFEAWIKPEDMVDPH
>CP022896.1|AXJ43997.1|1923081_1923903_+|Ribosomal-large-subunit-pseudouridine-synthase-D
MKFKIPENFNDLSLRDIFQQLKVPKKDLHHLNMSKDITINDKPARLMDKVHTGDDVFVPTIDEKSNYVPSYRYAQIKYEDDDMAIVMKPKGVKTHPNDLKESNTLMNHVIYTVDSDYVEPIHRLDQETVGLLIVAKNPLMKKILDRMLEDNDITRIYKANVKALLPLKPQTIDMPIGKDKFHSNKRRVSPTGQRAITHILTSKMIKETVCQLEIKLDTGRTHQIRVHLAEIGHPVIGDPLYGDSTLRQLELESYKIEFVHPLTKEVISVSLDD
>CP022896.1|AXJ44007.1|1941913_1942360_-|Peroxide-responsive-repressor-PerR
MSVEIESIEHELEESIASLRQAGVRITPQRQAILRYLISSHTHPTADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK
>CP022896.1|AXJ44008.1|1942456_1943416_-|Glyoxylate/hydroxypyruvate-reductase-B
MTYMKVVGLNRMREVETELQQRFSDVDFKFYKKASEIPESDLANLDILVGYDGGINEAFLRRCPNLKWIAWFATGVNTLPLDYIADHGILLTNGKGVQAKQLSEYILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQTVLFLGTGAIATRTAKLAKAFNMNLIGLSKSGQNKDEFDEIYTIESLESTLPNADIVINALPETQETIHLLKKKHFELMKDEALFINIGRGSIVKEALLIEVLKSRVIRHAYLDVFENEPLKPNHELYELDNVTITAHITGNDYEAKYDLLDIFKNNLVNFLNKNGLIENEADAKKGY
>CP022896.1|AXJ44009.1|1943412_1943868_-|Putative-peroxiredoxin-bcp
MLQKGEQFPIFKLENQDGTVITNDTLKGKKAIVYFYPRDNTPTCTTEACDFRDNLEMFNDLDVAVYGISGDSKKKHQNFIEKYGLNFDLLVDEDFKLAKETGVYQLKKSFGKESMGIVRTTFIIDEQGKVLDVIEKVKVKTQIEELKNILG
>CP022896.1|AXJ44010.1|1943948_1945238_+|Glutamate-1-semialdehyde-2,1-aminomutase-2
MNFSESERLQQLSNEYILGGVNSPSRSYKAVGGGAPVVMKEGHGAYLYDVDGNKFIDYLQAYGPIITGHAHPHITKAIQEQAAKGVLFGTPTELEIEFSKKLRDAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRNKIIKFAGSYHGHSDLVLVAAGSGPSQLGSPDSAGVPESVAREVITVPFNDINAYKEAIEFWGDEIAAVLVEPIVGNFGMVMPQPGFLEEVNEISHSNGTLVIYDEVITAFRFHYGAAQDLLGVIPDLTAFGKIVGGGLPIGGYGGRQDIMEQVAPLGPAYQAGTMAGNPLSMKAGIALLEVLEQDGVYEKLDSLGQQLEEGLLKLIEKHNITATINRIYGSLTLYFTDEKVTHYDQVEHSDGEAFGKFFKLMLNQGINLAPSKFEAWFLTTEHTEEDIKQTLKAADYAFSQMK
>CP022896.1|AXJ44011.1|1945479_1946625_+|Fusaric-acid-resistance-protein-family-protein
MNTNVRYSINLKGASLFLRLGARIFKTGIAIILAMSIASLLPDDVGLKALAGVSAVVAMQPSIYRSFKTVSDQALGNIIGAILSVTMVTIFSDNFIIMGVTVIVLIAILFKFNLAHVATLASVTALIIMGQHTGSFYITAFYRFVLVMIGVISSSLVNFVFLPPKFETKIYYNSLNISSDIFMWFKLVLNDTTEFNNIKQDSHNLKQRVEKLEKIYDYYSEERPITKKHIHQQNRKKILFREVVQTTRQAYEVLNKLSRYQNDLYLLNNNFLLQIKLDLDSLTAFHEQILASLSKKARYNVTHVDYELDNPQKKDLLSTFQHELINHPYQTEYSFANVMQIVAAIEEYRHHLEHLDRIRISFFTYHRSDADIEIVEEDFDL
>CP022896.1|AXJ44012.1|1946815_1948552_-|Putative-multidrug-export-ATP-binding/permease-protein
MIKRYLQFVKPYKYRIFATIIVGIIKFGIPMLIPLLIKYAIDGVINNHALTTDEKVHHLTIAIGIALFIFVIVRPPIEFIRQYLAQWTSNKILYDIRKKLYNHLQALSARFYANNQVGQVISRVINDVEQTKDFILTGLMNIWLDCITIIIALSIMFFLDVKLTLAALFIFPFYILTVYVFFGRLRKLTRERSQALAEVQGFLHERVQGISVVKSFAIEDNEAKNFDKKNTNFLTRALKHTRWNAYSFAAINTVTDIGPIIVIGVGAYLAISGSITVGTLAAFVGYLELLFGPLRRLVASFTTLTQSFASMDRVFQLIDEDYDIKNGVGAQPIEIKQGRIDIDHVSFQYNDNEAPILKDINLSIEKGETVAFVGMSGGGKSTLINLIPRFYDVTSGQILIDGHNIKDFLTGSLRNQIGLVQQDNILFSDTVKENILLGRPTATDEEVVEAAKMANAHDFIMNLPQGYDTEVGERGVKLSGGQKQRLSIARIFLNNPPILILDEATSALDLESESIIQEALDVLSKDRTTLIVAHRLSTITHADKIVVIENGHIVETGTHRELIAKQGAYEHLYSIQNL
>CP022896.1|AXJ44013.1|1948842_1949385_-|hypothetical-protein
MVRESIPKEGENIKIQSYKHDGKIHRVWSETTILKGTDHVVIGGNDHTLVTESDGRTWITREPAIVYFHSEYWFNVICMFREDGIYYYCNLSSPFVCDEEALKYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDIILRRNVDILQQWIEQKKGPFAPDFIKVWKDRYKKIRQY
>CP022896.1|AXJ44014.1|1949687_1950725_-|putative-A/G-specific-adenine-glycosylase-YfhQ
MYQQSSFKENLIHWFDENQREMPWRQTTNPYYIWLSEVMLQQTQVKTVIDYYHRFVERFPTVEVLSQASEDEVLKYWEGLGYYSRARNFHTAIKEVHDKYEGLVPKDPDQFKALKGVGPYTQAAVMSIAYNVPLATVDGNVFRVWSRLNDDYRDIKLQSTRKSYEQELLPYVTTEAGTFNQAMMELGALICTPKNPLCLFCPVQENCEAFDKGTFEKLPVKSKNVSKKVIEQSVFLIRNNQGQYLLQKRSEKLLHGMWQFPMFKSEHARREMTEKIGHDIQPVETPIFELKHQFTHLTWKIKVYAVSGTINIERLPDDMIWFDLSDRDQYTFPVPMSKIYQFING
>CP022896.1|AXJ44015.1|1950876_1951854_+|hypothetical-protein
MDTATHIAIGVGLTALATQDPAMASTFGATATTLIVGSLIPDGDTVLKLKDNATYISHHRGITHSIPFTILWPILITFLIFTFFSGTHPFHVWMWAQLAVFLHVFVDIFNSYGTQALRPITNKWIQLSVINTFDPIIFTVLCIGIVLWVVGLHPLAVFFPIIALLIIYYMIRFKMRAVIKQQALKAIQQEHHPVKVFVAPTIKFMEWRVAIQTDAHDYVGKAYGRNVVFSDKVERQKLSTDSILWKVKGNKDIRTFLNFSSIYRWQTTTLADGSTEIRLIDLRYLKNDHYSFVAIAHVTKDNVIDHSYIGWVFTEDKLQRKLYAK
>CP022896.1|AXJ44016.1|1952114_1952951_-|hypothetical-protein
MLDNIILYFKNLPHTKRYVTERLKQSWKSFLIVLAACLILIIASETLFSFSHLTDVKEVRWLFRLIALIVFAVLMFTIYISYHHYMNDFLVTKLFNISAATPVVIMSILSFIMLVILTMISALVKPVNFETSYIALFYFIVMATIFVGLISVTFGLIRLLTEKINIIFYGICVLCFLVLPIIFIPNPNHVFINHILMLNPMYYIVNGIAQSIIFGISSMENIPYHFYFILFLCLIAAVNFVLARYTTHAIYNKTSKVTQTDNQQDVSKDSTDEADTSS

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Crispr_ID: CP022896_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022896_4

1978681-1978872

Orphan

Consensus_repeat	Method
NNTCTNTGTTGGGGCCCNCACC	CRT

3 spacers

DEDDh

The CRISPR arrays of CP022896_4

>merge|CP022896|4|1978681-1978872|CRT
CTCTATGTTTGGGGCCCCACCCCAACTTGCACATTATTGTAAGCTGACAGAAAGTCAGCTTCTATGTTGGGGCCCCGCCAACTTGCATTGTCTGTAGAATTTCCTTTCGAAATTCTCTTTGTTGGGGCCCCACCCTAACTTGCACATTATTGTAAGCTGACAGAAAGTCAGCTTCTTTGTTGGGGCCCCACT

>CP022896|4|1|1978681-1978872|CRT
CTCTATGTTTGGGGCCCCACC	CCAACTTGCACATTATTGTAAGCTGACAGAAAGTCAG
CTTCTATGTTGGGGCCCCGCC	AACTTGCATTGTCTGTAGAATTTCCTTTCGAAAT
TCTCTTTGTTGGGGCCCCACC	CTAACTTGCACATTATTGTAAGCTGACAGAAAGTCAG
CTTCTTTGTTGGGGCCCCACT

Protein	Signature genes	Signature genes Name	Protein_function
CP022896.1\|AXJ44044.1\|1977591_1978539_-\|Diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|183982
CP022896.1\|AXJ44040.1\|1973511_1974066_+\|DNA-polymerase-III-PolC-type	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
CP022896.1\|AXJ44041.1\|1974132_1975203_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
CP022896.1\|AXJ44036.1\|1969644_1970058_-\|hypothetical-protein	unknown	unknown	unknown
CP022896.1\|AXJ44047.1\|1982260_1982563_-\|Aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase-subunit-C	unknown	unknown	gnl\|CDD\|178810
CP022896.1\|AXJ44053.1\|1990839_1991142_-\|Trp-repressor-protein	unknown	unknown	gnl\|CDD\|226893
CP022896.1\|AXJ44038.1\|1971015_1972329_-\|UDP-N-acetylmuramate--L-alanine-ligase	unknown	unknown	gnl\|CDD\|223840
CP022896.1\|AXJ44052.1\|1989964_1990657_-\|Heptaprenylglyceryl-phosphate-synthase	unknown	unknown	gnl\|CDD\|224560
CP022896.1\|AXJ44054.1\|1991250_1992546_-\|Adenylosuccinate-lyase	unknown	unknown	gnl\|CDD\|176464
CP022896.1\|AXJ44051.1\|1987775_1989968_-\|ATP-dependent-DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
CP022896.1\|AXJ44046.1\|1980801_1982259_-\|Glutamyl-tRNA(Gln)-amidotransferase-subunit-A	unknown	unknown	gnl\|CDD\|234572
CP022896.1\|AXJ44035.1\|1968469_1969456_+\|Fusaric-acid-resistance-protein-family-protein	unknown	unknown	gnl\|CDD\|226614
CP022896.1\|AXJ44049.1\|1984556_1985756_-\|CamS-sex-pheromone-cAM373-precursor	unknown	unknown	gnl\|CDD\|227188
CP022896.1\|AXJ44048.1\|1982929_1984468_+\|Sodium/proline-symporter	unknown	unknown	gnl\|CDD\|273981
CP022896.1\|AXJ44045.1\|1979361_1980789_-\|Aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase-subunit-B	unknown	unknown	gnl\|CDD\|235489
CP022896.1\|AXJ44039.1\|1972620_1973121_+\|Ferritin	unknown	unknown	gnl\|CDD\|224445
CP022896.1\|AXJ44042.1\|1975449_1975980_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378690
CP022896.1\|AXJ44037.1\|1970282_1971014_-\|cobyric-acid-synthase	unknown	unknown	gnl\|CDD\|225974
CP022896.1\|AXJ44050.1\|1985768_1987772_-\|DNA-ligase	unknown	unknown	gnl\|CDD\|236137
CP022896.1\|AXJ44043.1\|1976149_1977511_-\|putative-RNA-methyltransferase	unknown	unknown	gnl\|CDD\|225174

Protein	Function_ID	Function_description	E-value
CP022896.1\|AXJ44044.1\|1977591_1978539_-\|Diacylglycerol-kinase	gnl\|CDD\|183982	PRK13337, PRK13337, putative lipid kinase; Reviewed.	0
CP022896.1\|AXJ44040.1\|1973511_1974066_+\|DNA-polymerase-III-PolC-type	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
CP022896.1\|AXJ44041.1\|1974132_1975203_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
CP022896.1\|AXJ44047.1\|1982260_1982563_-\|Aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase-subunit-C	gnl\|CDD\|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	5.296e-34
CP022896.1\|AXJ44053.1\|1990839_1991142_-\|Trp-repressor-protein	gnl\|CDD\|226893	COG4496, COG4496, Uncharacterized protein conserved in bacteria [Function unknown].	1.66593e-59
CP022896.1\|AXJ44038.1\|1971015_1972329_-\|UDP-N-acetylmuramate--L-alanine-ligase	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	3.60835e-98
CP022896.1\|AXJ44052.1\|1989964_1990657_-\|Heptaprenylglyceryl-phosphate-synthase	gnl\|CDD\|224560	COG1646, COG1646, Predicted phosphate-binding enzymes, TIM-barrel fold [General function prediction only].	2.53994e-99
CP022896.1\|AXJ44054.1\|1991250_1992546_-\|Adenylosuccinate-lyase	gnl\|CDD\|176464	cd01360, Adenylsuccinate_lyase_1, Adenylsuccinate lyase (ASL)_subgroup 1. This subgroup contains bacterial and archeal proteins similar to ASL, a member of the Lyase class I family. Members of this family for the most part catalyze similar beta-elimination reactions in which a C-N or C-O bond is cleaved with the release of fumarate as one of the products. These proteins are active as tetramers. The four active sites of the homotetrameric enzyme are each formed by residues from three different subunits. ASL catalyzes two steps in the de novo purine biosynthesis: the conversion of 5-aminoimidazole-(N-succinylocarboxamide) ribotide (SAICAR) into 5-aminoimidazole-4-carboxamide ribotide (AICAR) and, the conversion of adenylsuccinate (SAMP) into adenosine monophosphate (AMP).	0
CP022896.1\|AXJ44051.1\|1987775_1989968_-\|ATP-dependent-DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
CP022896.1\|AXJ44046.1\|1980801_1982259_-\|Glutamyl-tRNA(Gln)-amidotransferase-subunit-A	gnl\|CDD\|234572	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA.	0
CP022896.1\|AXJ44035.1\|1968469_1969456_+\|Fusaric-acid-resistance-protein-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	9.69605e-76
CP022896.1\|AXJ44049.1\|1984556_1985756_-\|CamS-sex-pheromone-cAM373-precursor	gnl\|CDD\|227188	COG4851, CamS, Protein involved in sex pheromone biosynthesis [General function prediction only].	0
CP022896.1\|AXJ44048.1\|1982929_1984468_+\|Sodium/proline-symporter	gnl\|CDD\|273981	TIGR02121, Osmoregulated_proline_transporter, sodium/proline symporter. This family consists of the sodium/proline symporter (proline permease) from a number of Gram-negative and Gram-positive bacteria and from the archaeal genus Methanosarcina. Using the related pantothenate permease as an outgroup, candidate sequences from Bifidobacterium longum and several from archaea are found to be outside the clade defined by known proline permeases. These sequences, scoring between 570 and -40, define the range between trusted and noise cutoff scores. [Transport and binding proteins, Amino acids, peptides and amines].	0
CP022896.1\|AXJ44045.1\|1979361_1980789_-\|Aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase-subunit-B	gnl\|CDD\|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0
CP022896.1\|AXJ44039.1\|1972620_1973121_+\|Ferritin	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	6.02934e-74
CP022896.1\|AXJ44042.1\|1975449_1975980_-\|hypothetical-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.54005e-11
CP022896.1\|AXJ44037.1\|1970282_1971014_-\|cobyric-acid-synthase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	1.79354e-120
CP022896.1\|AXJ44050.1\|1985768_1987772_-\|DNA-ligase	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
CP022896.1\|AXJ44043.1\|1976149_1977511_-\|putative-RNA-methyltransferase	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	0

>CP022896.1|AXJ44044.1|1977591_1978539_-|Diacylglycerol-kinase
MRKRARIIYNPTSGKEQFKRELPDALIKLEKAGYETSAYATEKIGDATLEAERAMHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPFAYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGYFTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGGKLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE
>CP022896.1|AXJ44043.1|1976149_1977511_-|putative-RNA-methyltransferase
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMGSCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMVIFVTNGKNWPQKNAVVEKILDAFPNVTSIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYGVEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPSTQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
>CP022896.1|AXJ44042.1|1975449_1975980_-|hypothetical-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSAGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ
>CP022896.1|AXJ44041.1|1974132_1975203_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYRNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSTRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>CP022896.1|AXJ44040.1|1973511_1974066_+|DNA-polymerase-III-PolC-type
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>CP022896.1|AXJ44039.1|1972620_1973121_+|Ferritin
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEEAMFETHINYLTRIGDDSNALYLYEKALGTRTFDEE
>CP022896.1|AXJ44038.1|1971015_1972329_-|UDP-N-acetylmuramate--L-alanine-ligase
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNGDDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISRFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQAIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>CP022896.1|AXJ44037.1|1970282_1971014_-|cobyric-acid-synthase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHNFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEKQAKQVLIDRANRQKKSR
>CP022896.1|AXJ44036.1|1969644_1970058_-|hypothetical-protein
MKPTKVILKDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEIKFEFALFDSDMDNLKYIEYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMVTESGVSLRINVTKSGFTKFINELVSLH
>CP022896.1|AXJ44035.1|1968469_1969456_+|Fusaric-acid-resistance-protein-family-protein
MNGQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQEIILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>CP022896.1|AXJ44045.1|1979361_1980789_-|Aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase-subunit-B
MHFETVIGLEVHVELKTDSKMFSPSPAHFGAEPNSNTNVIDLAYPGVLPVVNKRAVDWAMRAAMALNMEIATESKFDRKNYFYPDNPKAYQISQFDQPIGENGYIDIEVDGETKRIGITRLHMEEDAGKSTHKGEYSLVDLNRQGTPLIEIVSEPDIRSPKEAYAYLEKLRSIIQYTGVSDVKMEEGSLRCDANISLRPYGQEKFGTKAELKNLNSFNYVRKGLEYEEKRQEEELLSGGEIGQETRRFDESTGKTILMRVKEGSDDYRYFPEPDIVPLYIDDAWKERVRQTIPELPDERKAKYVNELGLPAYDAHVLTLTKEMSDFFESTIEHGADVKLTSNWLMGGVNEYLNKNQVELLDTKLTPENLAGMIKLIEDGTMSSKIAKKVFPELAAKGGNAKQIMEDNGLVQISDEATLLKFVNEALDNNEQSVEDYKNGKGKAMGFLVGQIMKASKGQANPQLVNQLLKQELDKR
>CP022896.1|AXJ44046.1|1980801_1982259_-|Glutamyl-tRNA(Gln)-amidotransferase-subunit-A
MSIRYESVENLLTLIKDKKIKPSDVVKDIYDAIEETDPTIKSFLALDKENAIKKAQELDELQAKDQMDGKLFGIPMGIKDNIITNGLETTCASKMLEGFVPIYESTVMEKLHNENAVLIGKLNMDEFAMGGSTETSYFKKTVNPFDHKAVPGGSSGGSAAAVAAGLVPFSLGSDTGGSIRQPAAYCGVVGMKPTYGRVSRFGLVAFASSLDQIGPLTRNVKDNAIVLEAISGADANDSTSAPVDDVDFTSEIGKDIKGLKVALPKEYLGEGVADDVKEAVQNAVETLKSLGAVVEEVSLPNTKFGIPSYYVIASSEASSNLSRFDGIRYGYHSKEAHSLEELYKMSRSEGFGKEVKRRIFLGTFALSSGYYDAYYKKSQKVRTLIKNDFDKVFENYDVVVGPTAPTTAFNLGEEIDDPLTMYANDLLTTPVNLAGLPGISVPCGQSNGRPIGLQFIGKPFDEKTLYRVAYQYETQYNLHDVYEKL
>CP022896.1|AXJ44047.1|1982260_1982563_-|Aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase-subunit-C
MTKVTREEVEHIANLARLQISPEETEEMANTLESILDFAKQNDSADTEGVEPTYHVLDLQNVLREDKAIKGIPQELALKNAKETEDGQFKVPTIMNEEDA
>CP022896.1|AXJ44048.1|1982929_1984468_+|Sodium/proline-symporter
MLTMGTALSQQVDANWQTYIMIAVYFLILIVIGFYGYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWMIMGLPGSVYSTGLSAMWITIGLTLGAYINYFVVAPRLRVYTELAGDAITLPDFFKNRLNDKNNVLKIISGLIIVVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGYLAVSITDFFQGVIMLIAMVMVPIVAMMNLNGWGTFHDVAAMKPTNLNLFKGLSFIGIISLFSWGLGYFGQPHIIVRFMSIKSHKMLPKARRLGISWMAVGLLGAVAVGLTGIAFVPAYHIKLEDPETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLTEDFYKLVRGEEKAKTHQKEFVMVGRLSVLAVAIVAIAIAWNPNDTILNLVGNAWAGFGASFSPLVLFALYWKGLTRAGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIPGFIVSVIVTYVVSKLTKKPGAFVETDLNKVRDIVREK
>CP022896.1|AXJ44049.1|1984556_1985756_-|CamS-sex-pheromone-cAM373-precursor
MKRTLVLLITAIFILAACGNHKDDQAGKDNQKHNNSSNQVKEIATDKNVQGDNYRTLLPFKESQARGLLQDNMANSYNGGDFEDGLLNLSKEVFPTDKYLYQDGQFLDKKTINAYLNPKYTKREIDKMSEKDKKDKKANENLGLNPSHEGETDPEKIAEKSPAYLSNILEQDFYGGGDTKGKNIKGMTIGLAMNSVYYYKKEKDGPTFSKKLDDSEVKKQGKQMASEILSRLRENDDLKDIPIHFAIYKQSSEDSITPGEFITQATAEKSQTKLNEWHNINEKSALLPSSTAADYDENLNNNFKQFNDNLQSYFSNFTQAVGKVKFVDKKPQRLVVDLPIDYYGQAETIGITQYVTEQANKYFDKIDNYEIRIKDGNQPRALISKTKDDKEPQVHIYSN
>CP022896.1|AXJ44050.1|1985768_1987772_-|DNA-ligase
MADLSSRVNELHDLLNQYSYEYYVEDNPSVPDSEYDKLLHELIKIEEEHPEFKTVDSPTVRVGGEAQASFNKVNHDTPMLSLGNAFNEDDLRKFDQRIREQIGNVEYMCELKIDGLAVSLKYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPLNVEVRGEAYMPRRSFLRLNEEKEKNDEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFIYSVNDFTDFNARSQSEALDELDKLGFTTNKNRARVSDIDGVLEYIEKWTSQRESLPYDIDGIVIKVNDLDQQDEMGFTQKSPRWAIAYKFPAEEVVTKLLDIELSIGRTGVVTPTAILEPVKVAGTTVSRASLHNEDLIHDRDIRIGDSVVVKKAGDIIPEVVRSIPERRPEDAVTYHMPTHCPSCGHELVRIEGEVALRCINPKCQAQLVEGLIHFVSRQAMNIDGLGTKIIQQLYQSELIKDVADIFYLTEEDLLPLDRMGQKKVDNLLAAIQQAKDNSLENLLFGLGIRHLGVKASQVLAEKYETIDRLLTVTEAELVEIHDIGDKVAQSVVTYLENEDIRALIQKLKDKHVNMIYKGIKTSDIEGHPEFSGKTIVLTGKLHQMTRNEASKWLASQGAKVTSSVTKNTDVVIAGEDAGSKLTKAQSLGIEIWTEQQFVDKQNELNS
>CP022896.1|AXJ44051.1|1987775_1989968_-|ATP-dependent-DNA-helicase-PcrA
MNALLNHMNTEQSEAVKTTEGPLLIMAGAGSGKTRVLTHRIAYLLDEKDVSPYNVLAITFTNKAAREMKERVQKLVGDQAEVIWMSTFHSMCVRILRRDADRIGIERNFTIIDPTDQKSVIKDVLKNENIDSKKFEPRMFIGAISNLKNELKTPADAQKEATDYHSQMVATVYSGYQRQLSRNEALDFDDLIMTTINLFERVPEVLEYYQNKFQYIHVDEYQDTNKAQYTLVKLLASKFKNLCVVGDSDQSIYGWRGADIQNILSFEKDYPEANTIFLEQNYRSTKTILNAANEVIKNNSERKPKGLWTANTNGEKIHYYEAMTERDEAEFVIREIMKHQRNGKKYQDMAILYRTNAQSRVLEETFMKSNMPYTMVGGQKFYDRKEIKDLLSYLRIIANSNDDISLQRIINVPKRGVGPSSVEKVQNYALQNNISMFDALGEADFIGLSKKVTQECLNFYELIQSLIKEQEFLEIHEIVDEVLQKSGYREMLERENTLESRSRLENIDEFMSVPKDYEENTPLEEQSLINFLTDLSLVADIDEADTENGVTLMTMHSAKGLEFPIVFIMGMEESLFPHIRAIKSEDDHEMQEERRICYVAITRAEEVLYITHATSRMLFGRPQSNMPSRFLKEIPESLLENHSSGKRQTIQPKAKPFAKRGFSQRTTSTKKQVSSSDWNVGDKVMHKAWGEGMVSNVNEKNGSIELDIIFKSQGPKRLLAQFAPIEKKED
>CP022896.1|AXJ44052.1|1989964_1990657_-|Heptaprenylglyceryl-phosphate-synthase
MYDIKKWRHIFKLDPAKHISDDDLDAICMSQTDAIMIGGTDDVTEDNVIHLMSRVRRYPLPLVLEISNIESVMPGFDFYFVPTVLNSTDVAFHNGTLLEALKTYGHSIDFEEVIFEGYVVCNADSKVAKHTKANTDLTTEDLEAYAQMVNHLYRLPVMYIEYSGIYGDVSKVQAVSEHLTETQLFYGGGISSEQQATEMAAIADTIIVGDIIYKDIKKALKTVKIKESSK
>CP022896.1|AXJ44053.1|1990839_1991142_-|Trp-repressor-protein
MQIEKLRGAALDELFDAILTLENREECYQFFDDLCTVNEIQSLSQRLQVAKMIKQGYTYATIEQESGASTATISRVKRSLQWGNDAYTMILDRMNIETNE
>CP022896.1|AXJ44054.1|1991250_1992546_-|Adenylosuccinate-lyase
MIERYSREEMSNIWTDQNRYEAWLEVEILACEAWSELGHIPKADVQKIRQNAKVNVERAQEIEQETRHDVVAFTRQVSETLGEERKWVHYGLTSTDVVDTALSFVIKQANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAEPTTFGVKMALWYTEMQRNLQRFKQVREEIEVGKMSGAVGTFANIPPEIESYVCKHLGIGTAPVSTQTLQRDRHAYYIATLALIATSLEKFAVEIRNLQKTETREVEEAFAKGQKGSSAMPHKRNPIGSENITGISRVIRGYITTAYENVPLWHERDISHSSAERIMLPDVTIALDYALNRFTNIVDRLTVFEDNMRNNIDKTFGLIFSQRVLLALINKGMVREEAYDKVQPKAMISWETKTPFRELIEQDESITSVLTKEELDECFDPKHHLNQVDTIFERAGLA

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Crispr_ID: CP022896_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022896_5

2224488-2224689

Orphan

Consensus_repeat	Method
TCCTTGGTTGGCAGGTGCAGCTGGATGTGCTGTA	PILER-CR

2 spacers

The CRISPR arrays of CP022896_5

>merge|CP022896|5|2224488-2224689|PILER-CR
TGCTTGGTTGGCAGGTGCTGCTTGATTTCCAGGTTGTGCTTGTGCAGCGTTATTCGGATCAGCTTGATTACCTTGTCCAGCTGGTTGTGCTGTACCTGCTGCCGGTTGTGCTGCGCCTCCTGCTGGATTAGCCTGTCCACCTTGGTTTGCTGGTTGTGCTGCTGGTTGTCCTTGGTTGGCAGGTGCAGCTGGCTGTGCTGTA

>CP022896|5|1|2224488-2224689|PILER-CR
TGCTTGGTTGGCAGGTGCTGCTTGATTTCCAGGT	TGTGCTTGTGCAGCGTTATTCGGATCAGCTTGATTACCTTGTCCAGCT
GGTTGTGCTGTACCTGCTGCCGGTTGTGCTGCGC	CTCCTGCTGGATTAGCCTGTCCACCTTGGTTTGCTGGTTGTGCTGCTGGTTGTCCTTGGTTGGCAGGTGCAGCT
GGCTGTGCTGTA

Protein	Signature genes	Signature genes Name	Protein_function
CP022896.1\|AXJ44286.1\|2235635_2236700_-\|Flagellum-site-determining-protein-YlxH	unknown	unknown	gnl\|CDD\|378455
CP022896.1\|AXJ44288.1\|2237895_2238291_-\|putative-transport-protein-HsrA	unknown	unknown	gnl\|CDD\|341046
CP022896.1\|AXJ44281.1\|2216081_2217188_+\|Mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
CP022896.1\|AXJ44273.1\|2202453_2203545_+\|hypothetical-protein	unknown	unknown	unknown
CP022896.1\|AXJ44275.1\|2207505_2208363_-\|Putative-phosphatase-YwpJ	unknown	unknown	gnl\|CDD\|223635
CP022896.1\|AXJ44289.1\|2238479_2238947_-\|Multidrug-resistance-efflux-pump-SepA	unknown	unknown	gnl\|CDD\|374975
CP022896.1\|AXJ44279.1\|2213503_2215636_+\|Transcriptional-regulator-MtlR	unknown	unknown	gnl\|CDD\|226234
CP022896.1\|AXJ44272.1\|2201207_2202188_+\|Cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter	unknown	unknown	gnl\|CDD\|224151
CP022896.1\|AXJ44284.1\|2227493_2228303_-\|DNA-integrity-scanning-protein-DisA	unknown	unknown	gnl\|CDD\|224539
CP022896.1\|AXJ44285.1\|2228492_2229401_-\|Arginase	unknown	unknown	gnl\|CDD\|212515
CP022896.1\|AXJ44287.1\|2236847_2237936_-\|putative-multidrug-resistance-protein-EmrY	unknown	unknown	gnl\|CDD\|341046
CP022896.1\|AXJ44291.1\|2240595_2241279_-\|hemolysin-III-related	unknown	unknown	gnl\|CDD\|224191
CP022896.1\|AXJ44280.1\|2215647_2216082_+\|Mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014
CP022896.1\|AXJ44290.1\|2239074_2240418_-\|Multidrug-resistance-protein-3	unknown	unknown	gnl\|CDD\|129794
CP022896.1\|AXJ44282.1\|2225177_2226533_-\|Phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
CP022896.1\|AXJ44278.1\|2211930_2213469_+\|PTS-system-mannitol-specific-EIICB-component	unknown	unknown	gnl\|CDD\|225123
CP022896.1\|AXJ44277.1\|2209444_2211250_-\|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]	unknown	unknown	gnl\|CDD\|234729
CP022896.1\|AXJ44274.1\|2203832_2205479_+\|Transposase-DDE-domain-protein	unknown	unknown	gnl\|CDD\|226192
CP022896.1\|AXJ44283.1\|2226559_2227492_-\|YbbR-like-protein	unknown	unknown	gnl\|CDD\|227193
CP022896.1\|AXJ44276.1\|2208430_2209213_-\|putative-ABC-transporter-ATP-binding-protein-YlmA	unknown	unknown	gnl\|CDD\|224044

Protein	Function_ID	Function_description	E-value
CP022896.1\|AXJ44286.1\|2235635_2236700_-\|Flagellum-site-determining-protein-YlxH	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	5.47694e-116
CP022896.1\|AXJ44284.1\|2227493_2228303_-\|DNA-integrity-scanning-protein-DisA	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.13611e-103
CP022896.1\|AXJ44281.1\|2216081_2217188_+\|Mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
CP022896.1\|AXJ44275.1\|2207505_2208363_-\|Putative-phosphatase-YwpJ	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	1.15818e-59
CP022896.1\|AXJ44289.1\|2238479_2238947_-\|Multidrug-resistance-efflux-pump-SepA	gnl\|CDD\|374975	pfam17080, SepA, Multidrug Resistance efflux pump. SepA is a drug efflux protein that is involved in bacterial multidrug resistance. It is predicted to have four transmembrane domains.	8.07477e-30
CP022896.1\|AXJ44279.1\|2213503_2215636_+\|Transcriptional-regulator-MtlR	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	9.39374e-67
CP022896.1\|AXJ44272.1\|2201207_2202188_+\|Cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	4.09175e-108
CP022896.1\|AXJ44288.1\|2237895_2238291_-\|putative-transport-protein-HsrA	gnl\|CDD\|341046	cd17503, MFS_LmrB_MDR_like, Bacillus subtilis lincomycin resistance protein (LmrB) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including Bacillus subtilis lincomycin resistance protein LmrB, and several proteins from Escherichia coli such as the putative MDR transporters EmrB, MdtD, and YieQ. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. For example, MMR confers resistance to the epoxide antibiotic methylenomycin. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.88225e-30
CP022896.1\|AXJ44285.1\|2228492_2229401_-\|Arginase	gnl\|CDD\|212515	cd09989, Arginase, Arginase family. This family includes arginase, also known as arginase-like amidino hydrolase family, and related proteins. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid. In vertebrates, at least two isozymes have been identified: type I (ARG1) cytoplasmic or hepatic liver-type arginase and type II (ARG2) mitochondrial or non-hepatic arginase. Point mutations in human arginase ARG1 gene lead to hyperargininemia with consequent mental disorders, retarded development and early death. Hyperargininemia is associated with a several-fold increase in the activity of the mitochondrial arginase (ARG2), causing persistent ureagenesis in patients. ARG2 overexpression plays a critical role in the pathophysiology of cholesterol mediated endothelial dysfunction. Thus, arginase is a therapeutic target to treat asthma, erectile dysfunction, atherosclerosis and cancer.	5.94976e-145
CP022896.1\|AXJ44287.1\|2236847_2237936_-\|putative-multidrug-resistance-protein-EmrY	gnl\|CDD\|341046	cd17503, MFS_LmrB_MDR_like, Bacillus subtilis lincomycin resistance protein (LmrB) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including Bacillus subtilis lincomycin resistance protein LmrB, and several proteins from Escherichia coli such as the putative MDR transporters EmrB, MdtD, and YieQ. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. For example, MMR confers resistance to the epoxide antibiotic methylenomycin. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.17545e-51
CP022896.1\|AXJ44291.1\|2240595_2241279_-\|hemolysin-III-related	gnl\|CDD\|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	4.64044e-66
CP022896.1\|AXJ44280.1\|2215647_2216082_+\|Mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	6.01856e-62
CP022896.1\|AXJ44290.1\|2239074_2240418_-\|Multidrug-resistance-protein-3	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.31901e-37
CP022896.1\|AXJ44282.1\|2225177_2226533_-\|Phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
CP022896.1\|AXJ44278.1\|2211930_2213469_+\|PTS-system-mannitol-specific-EIICB-component	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
CP022896.1\|AXJ44277.1\|2209444_2211250_-\|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP022896.1\|AXJ44274.1\|2203832_2205479_+\|Transposase-DDE-domain-protein	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.2166e-37
CP022896.1\|AXJ44283.1\|2226559_2227492_-\|YbbR-like-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	4.21538e-117
CP022896.1\|AXJ44276.1\|2208430_2209213_-\|putative-ABC-transporter-ATP-binding-protein-YlmA	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.75723e-107

>CP022896.1|AXJ44281.1|2216081_2217188_+|Mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALATGHQYDVILADESKTTTRVNNVAAINSMQPSEELKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLAYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>CP022896.1|AXJ44280.1|2215647_2216082_+|Mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEGNVDRIVQAKSAEEIKQVFEEADA
>CP022896.1|AXJ44279.1|2213503_2215636_+|Transcriptional-regulator-MtlR
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRITGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNLAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVKKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETRDKSSNMIDKDDVHIETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLISDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>CP022896.1|AXJ44278.1|2211930_2213469_+|PTS-system-mannitol-specific-EIICB-component
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWFPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFFGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLATLVSFVVAALIMKFTKEPKQDLEAATAQMETTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSLDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>CP022896.1|AXJ44277.1|2209444_2211250_-|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVTLQLISYYAALHRDLDVDKPRNLAKSVTVE
>CP022896.1|AXJ44276.1|2208430_2209213_-|putative-ABC-transporter-ATP-binding-protein-YlmA
MLIQLDQVGRMKQGKTILKNISWQINEGDKWILYGLNGAGKTTLLNILNAYEPATTGYVNLFGKMPGKVGYSTETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>CP022896.1|AXJ44275.1|2207505_2208363_-|Putative-phosphatase-YwpJ
MDNVKAIFLDMDGTILHENNQASTYTKDVINRLREKGYKVFLATGRSHSEIHQLVPEDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQIINLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIEHFGINQKETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>CP022896.1|AXJ44274.1|2203832_2205479_+|Transposase-DDE-domain-protein
MYKNYNMTQLTLPIETSVRIPQNDISRYVNEIVETIPDSEFDEFRHHRGATSYHPKMMLKIILYAYTQSVFSGRRIEKLLHDSIRLMWLAQNQTPSYKTINRFRVNPNTDALIESLFIQFHSQCLKQNLIDDNSIFIDGTKVEANANRYTFVWKKSIQNHESKLNENSKALYRDLVEEKIIPEIKEDGDSDLTIEEIDLIGSHLDKEIEDLNHSIQNEDCTQIRKQTRKKRTEIKKFKKKFDDYSERKSKYEEQKSILKDRNSFSKTDHDATFMRMKEDHMKNGQLKPGYNLQIATNSQFVLSYDLFQNPTDTRTLIPFLTMIQNTFGYLPEYIVADAGYGSEQNYMAIIDDFNKTPLITYGMFIKDKTRKFKSDIFNTQNWKYDELNDEFICPNNKRIGFKRYAYRNDRYGFKRDFKLYECDDCSACSLRQQCMKPNSKSNKKIMKNYNWEYFKAQINQKLSEPETKKIYSQRKIDVEPVFGFMKAILGFTRMSVRGINKVKRELGFVLMALNIRKIVARRAVYYQIHLKKADFYQIINRNQLFYIA
>CP022896.1|AXJ44273.1|2202453_2203545_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLVGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLVIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVITIILFVVIHAVILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>CP022896.1|AXJ44272.1|2201207_2202188_+|Cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALIAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVIATIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHSHHAHHHAHVH
>CP022896.1|AXJ44282.1|2225177_2226533_-|Phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
>CP022896.1|AXJ44283.1|2226559_2227492_-|YbbR-like-protein
MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKITGGEEQLNDIAYLKATFKTNKKINGDTKDIAEVTAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVSKAEPSETKAYINVK
>CP022896.1|AXJ44284.1|2227493_2228303_-|DNA-integrity-scanning-protein-DisA
MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQLLKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFLKRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNISQELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEVSDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK
>CP022896.1|AXJ44285.1|2228492_2229401_-|Arginase
MTKKKGIDIIGVPSTFGQRKLGVDLGPTAIRYAGLIPRLKQLDLDVNDKGDIKVSAVDIEKFQSEQNGLRNYDEIIDVTQKLNKEVSASIENNRFPLVLGGDHSIAIGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLTYRESHFALELLHQSQSVTSMDLVEVNPLIDHNNHTAEQSVSLVGTFFGETLL
>CP022896.1|AXJ44286.1|2235635_2236700_-|Flagellum-site-determining-protein-YlxH
MLTVDQVKELIGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKVAMAQLGGAPQLDLQMAVVNVLKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGIDEKPGINGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVRWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
>CP022896.1|AXJ44287.1|2236847_2237936_-|putative-multidrug-resistance-protein-EmrY
MPLMQFTLFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIALVAFIFGLISISSYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPVVIGAMIISSIIIYLFIRRQFNISNALLNLSVFKNRTFALCTISSMIIMMSMVGPALLIPLYVQNSLALSALLFGLVIMPGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVYAIRMFSVSLLMMPINTTGINSLKNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFGAKIFSSTSPSHLTATEIKQQSIAIGVDISFAFVAVLVMAAYVIALFIREPKEIESNRRKF
>CP022896.1|AXJ44288.1|2237895_2238291_-|putative-transport-protein-HsrA
MAKVELTTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELNINESTSQWLVTGFMLVNGVMIPLTAYLMDRIKTRPLYLAAMGTFLVGSIVAAMAPNFGVLMLARVIQAMGGRRTHAFNAIHIVYVIQ
>CP022896.1|AXJ44289.1|2238479_2238947_-|Multidrug-resistance-efflux-pump-SepA
MNYLKHKFYNLLTTIIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIVFAVEHLMDYFRKMLPENAYFRGATFHLISYMVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>CP022896.1|AXJ44290.1|2239074_2240418_-|Multidrug-resistance-protein-3
MRLKSIVTVIALILIMFMAAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLTRFKIIYIAIAGLTLFTVGSLMSGLSTHFSMLVISRVIQGFGSGVMMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVVWTFHFPEEETVAKSKFDTKGITLFYIFIGLIMFALLNQQHLYLNIIGFVLAILVALRLFNVEKKVSSPFLPVAEFNRMITLVFITDLLTAVCLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHHIEAKLSRKVIYLSSFTLLLLSSIIIAFGIKLPILIACVLILSGLSFGYIYTKDSVIVQEETSPIQMKKMMSFYGLTKNLGASIGSTIMGYLYALKSGLFGANLHNILGVVSLISVGLIVVWLIFYREAASQTKE
>CP022896.1|AXJ44291.1|2240595_2241279_-|hemolysin-III-related
MSKSSEKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLVLPYAAVHSYIAYGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMIYVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMGWVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLLHLIAILYFM

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Crispr_ID: CP022896_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022896_6

2283039-2283164

Orphan

Consensus_repeat	Method
CCTCTTTACTCGAAAGCTCACAAAACTCTTGATATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022896_6

>merge|CP022896|6|2283039-2283164|CRISPRCasFinder
CCTCTTTACTCGAAAGCTCACAAAACTCTTGATATCACTGGTTTCTCATGATTTTTTAATGTTTTTATTTTGAGTTACTCGAAAATTTTCCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCA

>CP022896|6|4|2283039-2283164|CRISPRCasFinder
CCTCTTTACTCGAAAGCTCACAAAACTCTTGATATCA	CTGGTTTCTCATGATTTTTTAATGTTTTTATTTTGAGTTACTCGAAAATTTT
CCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCA

Protein	Signature genes	Signature genes Name	Protein_function
CP022896.1\|AXJ44339.1\|2291561_2291930_-\|50S-ribosomal-protein-L17	unknown	unknown	gnl\|CDD\|235522
CP022896.1\|AXJ44335.1\|2287699_2288560_-\|Energy-coupling-factor-transporter-ATP-binding-protein-EcfA2	unknown	unknown	gnl\|CDD\|184205
CP022896.1\|AXJ44326.1\|2277160_2277976_-\|putative-hydrolase	unknown	unknown	gnl\|CDD\|319792
CP022896.1\|AXJ44321.1\|2271522_2271648_-\|hypothetical-protein	unknown	unknown	unknown
CP022896.1\|AXJ44323.1\|2272786_2273203_-\|HTH-type-transcriptional-regulator-AdhR	unknown	unknown	gnl\|CDD\|133384
CP022896.1\|AXJ44336.1\|2288556_2289366_-\|Energy-coupling-factor-transporter-ATP-binding-protein-EcfA1	unknown	unknown	gnl\|CDD\|184207
CP022896.1\|AXJ44332.1\|2285418_2285856_-\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
CP022896.1\|AXJ44328.1\|2279086_2279791_-\|Alpha-acetolactate-decarboxylase	unknown	unknown	gnl\|CDD\|226058
CP022896.1\|AXJ44322.1\|2271868_2272717_-\|putative-oxidoreductase	unknown	unknown	gnl\|CDD\|381359
CP022896.1\|AXJ44324.1\|2273609_2276036_+\|Hyaluronate-lyase-precursor	unknown	unknown	gnl\|CDD\|238517
CP022896.1\|AXJ44338.1\|2290520_2291309_+\|Integrase-core-domain-protein	unknown	unknown	gnl\|CDD\|222853
CP022896.1\|AXJ44320.1\|2271274_2271568_-\|hypothetical-protein	unknown	unknown	unknown
CP022896.1\|AXJ44334.1\|2286903_2287710_-\|Energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
CP022896.1\|AXJ44325.1\|2276095_2276950_-\|Murein-DD-endopeptidase-MepM	unknown	unknown	gnl\|CDD\|366703
CP022896.1\|AXJ44337.1\|2289768_2290497_+\|Transposase	unknown	unknown	gnl\|CDD\|379233
CP022896.1\|AXJ44327.1\|2278270_2278696_+\|65-kDa-membrane-protein-precursor	unknown	unknown	gnl\|CDD\|367591
CP022896.1\|AXJ44331.1\|2285006_2285405_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
CP022896.1\|AXJ44333.1\|2286104_2286899_-\|tRNA-pseudouridine-synthase-A	unknown	unknown	gnl\|CDD\|234577
CP022896.1\|AXJ44329.1\|2279827_2281492_-\|Acetolactate-synthase	unknown	unknown	gnl\|CDD\|236312
CP022896.1\|AXJ44330.1\|2283221_2284658_-\|Divergent-AAA-domain-protein	unknown	unknown	gnl\|CDD\|225420

Protein	Function_ID	Function_description	E-value
CP022896.1\|AXJ44339.1\|2291561_2291930_-\|50S-ribosomal-protein-L17	gnl\|CDD\|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	2.70058e-62
CP022896.1\|AXJ44335.1\|2287699_2288560_-\|Energy-coupling-factor-transporter-ATP-binding-protein-EcfA2	gnl\|CDD\|184205	PRK13646, cbiO, energy-coupling factor transporter ATPase.	0
CP022896.1\|AXJ44326.1\|2277160_2277976_-\|putative-hydrolase	gnl\|CDD\|319792	cd02605, HAD_SPP, sucrose-phosphatase, similar to Synechocystis sp PCC 6803 SPP. Sucrose-phosphatase (SPP; EC 3.1.3.24) catalyzes the dephosphorylation of sucrose-6(F)-phosphate (Suc6P)-the final step in the pathway of sucrose biosynthesis in plants and cyanobacteria. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.06188e-100
CP022896.1\|AXJ44323.1\|2272786_2273203_-\|HTH-type-transcriptional-regulator-AdhR	gnl\|CDD\|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	5.51415e-41
CP022896.1\|AXJ44336.1\|2288556_2289366_-\|Energy-coupling-factor-transporter-ATP-binding-protein-EcfA1	gnl\|CDD\|184207	PRK13648, cbiO, cobalt transporter ATP-binding subunit; Provisional.	0
CP022896.1\|AXJ44332.1\|2285418_2285856_-\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	4.91074e-100
CP022896.1\|AXJ44328.1\|2279086_2279791_-\|Alpha-acetolactate-decarboxylase	gnl\|CDD\|226058	COG3527, AlsD, Alpha-acetolactate decarboxylase [Secondary metabolites biosynthesis, transport, and catabolism].	1.39507e-119
CP022896.1\|AXJ44322.1\|2271868_2272717_-\|putative-oxidoreductase	gnl\|CDD\|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	3.15275e-150
CP022896.1\|AXJ44324.1\|2273609_2276036_+\|Hyaluronate-lyase-precursor	gnl\|CDD\|238517	cd01083, GAG_Lyase, Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.	0
CP022896.1\|AXJ44338.1\|2290520_2291309_+\|Integrase-core-domain-protein	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.91633e-47
CP022896.1\|AXJ44337.1\|2289768_2290497_+\|Transposase	gnl\|CDD\|379233	pfam13518, HTH_28, Helix-turn-helix domain. This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.	2.03349e-13
CP022896.1\|AXJ44334.1\|2286903_2287710_-\|Energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	2.81787e-49
CP022896.1\|AXJ44325.1\|2276095_2276950_-\|Murein-DD-endopeptidase-MepM	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	1.18512e-22
CP022896.1\|AXJ44327.1\|2278270_2278696_+\|65-kDa-membrane-protein-precursor	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	8.17372e-34
CP022896.1\|AXJ44331.1\|2285006_2285405_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	2.2295e-82
CP022896.1\|AXJ44333.1\|2286104_2286899_-\|tRNA-pseudouridine-synthase-A	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	1.21958e-120
CP022896.1\|AXJ44329.1\|2279827_2281492_-\|Acetolactate-synthase	gnl\|CDD\|236312	PRK08617, PRK08617, acetolactate synthase AlsS.	0
CP022896.1\|AXJ44330.1\|2283221_2284658_-\|Divergent-AAA-domain-protein	gnl\|CDD\|225420	COG2865, COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription].	3.62307e-63

>CP022896.1|AXJ44329.1|2279827_2281492_-|Acetolactate-synthase
MTDKKYTAADMVIDTLKNNGVEYVFGIPGAKIDYLFNALIDDGPELIVTRHEQNAAMMAQGIGRLTGKPGVVLVTSGPGVSNLTTGLLTATSEGDPVLALGGQVKRNDLLRLTHQSIDNAALLKYSSKYSEEVQDPESLSEVMTNAIRIATSGKNGASFISIPQDVISSPVESKAISLCQKPNLGVPSEQDINDVIEAIKNASFPVLLAGMRSSSADETNAIRKLVERTNLPVVETFQGAGVISRELENHFFGRVGLFRNQVGDELLRKSDLVVTIGYGPIEYEASNWNKELETQIINIDEVQAEITNYMQPKKELIGNIAKTIEMISEKVDEPFINQQHLDELEQLRTHIDEETGIKATHEEGILHPVEIIESMQKVLTDDTTVTVDVGSHYIWMARNFRSYNPRHLLFSNGMQTLGVALPWAISAALVRPNTQVVSVAGDGGFLFSSQDLETAVRKNLNIIQLIWNDGKYNMVEFQEEMKYKRSSGVDFGPVDFVKYAESFGAKGLRVTNQEELEAAIKEGYETDGPVLIDIPVNYKDNIKLSTNMLPDVFN
>CP022896.1|AXJ44328.1|2279086_2279791_-|Alpha-acetolactate-decarboxylase
MASVLYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNGEVIFLDGKAYHANEHKEFVELKGDELTPYATVTKFVADTSYETKDKSSEAVFAEIKEKMLSENLFSAVKISGLFKKMHVRMMPAQEPPYTRLIDSARRQPEQTETYVKGAVVGFFTPELFHGIGSAGFHVHFANDDRNFGGHVLDFEVEDVKVEIQNIETFEQHFPIQDEDFINANIDYKDIADEIREAE
>CP022896.1|AXJ44327.1|2278270_2278696_+|65-kDa-membrane-protein-precursor
MKLKSFVTATLALGLLSTVGAALPSHEASADSNNGYKEMTMDGYHTVPYTISVDGITALHRTYFVFPENKKVLYQEIDSKVKNQLASQRGVTTEKINNAQTATYTLTLNDGNKKVVNLKKNDDAKNSIDPSTIKQIQIVVK
>CP022896.1|AXJ44326.1|2277160_2277976_-|putative-hydrolase
MSKRLLLFDFDETYFKHNTNEEDLSHLREMEKLLEKLTNNNEVITVVLTGSTFQSVMDKMDQVNMTFKPLHIFSDLSSKMFTWNNGEYVESETYKKKVLSEPFLFEDIEDILHHISAQYNVEFIPQRAFEGNETHYNFYFHSTGNHNNDRRILEVLVRYANDQNYTARFSRSNPLAGDPENAYDIDFTPSNAGKLYATQFLMKKYNIPVKSILGFGDSGNDEAYLSYLEHAYLMSNSRDEALKQKFRLTKYPYYQGITLHVKEFVEGKYDY
>CP022896.1|AXJ44325.1|2276095_2276950_-|Murein-DD-endopeptidase-MepM
MNKTNFGDYLNKSKSRKIYKIFDQNLKREFSYWQFRKLFKSYTWQSDVHELKVCTQNDGTIEQIWIDKANQFGVAVTWKDNSIIGFVMRPLINYDAIKNETTLKYAVPTTDCYEVFWGGDNELYNYHYLYPHQRYAIDLVIKEKHKTYKNLGKVNADYFCFGKDIIAPANGTVEKVVNGVQDNSIGSTKESQFLGNYIVIKHAENEYSLIAHLQQYSIIVNEGQNVKYGDIIGKVGNSGNSTEPHIHFQVMNDKNIEACTSLKIRFINNRELIKGDVVCGLQGE
>CP022896.1|AXJ44324.1|2273609_2276036_+|Hyaluronate-lyase-precursor
MTYRMKKWQKLSTITLLMAGVITLNGGEFRSIDKHQIAVADTNVQTTDYEKLRNIWLDVNYGYDKYDENNPDMKKKFEATENEAEKLLKEMKTESDRKYLWESSKDLDTKSADMTRTYRNIEKISEAMKHKNTKLKTDENKTKVKDALEWLHKNAYGKEPDKKVADLTSNFKNKTSRNTNLNWWDYEIGTPRALTNTLILLQEDFTDEEKKKYTAPIKTFAPDSDKILSSVGKSEPAKGGNLVDISKVKLLESIIEEDKDMMKKSIDSFNTVFTYAQNSATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPMIKETPFNDSNQNDTTLKSWIDDGFMPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDTMDKSTKAKYKKIVKTSVESDSSYKQTDYLSSYSDISKMKSLMEDSTISTNGLTQQLKIYNDMDRVTYHNKGLDFAFGLSMTSKNVARYESINGENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLDNEEPKSTDVKKSSKTFVGGTKFDDQHASIGMDFENQDKTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANDYKLYKDDTQTTNSDNQETNSLFLESTNSTQNNIGYHFLNESKITVKKESHTGKWSDINKSQKDIQKTDEYYEVTQKHSNTDSKYAYVLYPGLSKDVFKSKASKVTVVKQEDDFHVVKDNESVWAGINYSDSAKTFEINNTKVEVKAKGMFILTKKDDNTYECSFYNPESTNSVSDIESKISMTGYSIINKNTSTSNESGVRFELTK
>CP022896.1|AXJ44323.1|2272786_2273203_-|HTH-type-transcriptional-regulator-AdhR
MKTKEVVALMNISQDTLRYYEKVGVIPPVNRDENGYRIYNDNDLNWIYLVKNLRNAGVSIESLIEFCRLAQLPKNENIQAQQKQILNKQLEELNENLKTIHDARDLLQYKIDNYDNHIAKINASDNHDDNVERLWERK
>CP022896.1|AXJ44322.1|2271868_2272717_-|putative-oxidoreductase
MNHIEISKDVKIPVLGFGVFQIPQEQTAEAVKEAIKAGYRHIDTAQSYLNETEVGQGIEASGIDRSELFITTKVWIENVNYEDTIKSIERSLQRLNLDYIDLVLIHQPYNDVYGSWRALEELKETGKIKAIGVSNFGVDRIVDLGIHNQIQPQVNQIEINPFHQQEEQVAALQQENVVVEAWAPFAEGKNQLFQNQLLQAIADKYNKSIAQVILRWLVERDIVVLAKSVNPERMAQNLDIFDFELTEEDKQQIATLEESNSQFFSHADPEMIKALTSRELDV
>CP022896.1|AXJ44321.1|2271522_2271648_-|hypothetical-protein
MTYIPFSIITLITGIIMHMTMYFVKFECRKMPLFMTIIFTI
>CP022896.1|AXJ44320.1|2271274_2271568_-|hypothetical-protein
MSENAIIHDDYFYNLKAVKTHNIAKNVNKSLLNDKGVSIGKFIQKLKGKNPTWRYPKIKWTISKNKGQSYGGSYWKLINNKGKRIASLTKEGKILRE
>CP022896.1|AXJ44330.1|2283221_2284658_-|Divergent-AAA-domain-protein
MTSSKYIEYLQTEVEGQLLDRKRASINPKDVAQHISAFANAEGGKLVIGIEDNGEISGFNHSKAKKKEVYIEAPFEHLYRIPKYTYEIIEVKKRDGTMDEILIFDIEPSYDAIITLKDDSVYLRINDKSRKLTHNQITNLEYDRGSRRFEEELVEYSSIEDVNEELVDEFKQLLNTNVDNEKLLKARGFMREGKLTVAGLLLFSNHINVYLPGARIRFMRYEGTKEESGTRLNIVKDITFDKALPVAIREARAFINTQLREYTFLGKEGRFVTLPEYPEFAWFEGMINSIVHRRYDNQGDHIRIKMFDDRLEISSPGALPASVTLENIKEERYSRNPKLAAALTQYKWVRESNEGVGRIFDEMKQYFLDDPVYSEPNNSSVQLALKNNIIARKKRETGRVSNIITPELFESLNEQQELIVRHLYNQGELTASKIANIIQRSVPTARKRLKELEEMNIISTHGSSKNDPKRTYYLLGFE
>CP022896.1|AXJ44331.1|2285006_2285405_-|30S-ribosomal-protein-S9
MTLAQVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFESLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGLLTRDPRMKERKKPGLKAARRSPQFSKR
>CP022896.1|AXJ44332.1|2285418_2285856_-|50S-ribosomal-protein-L13
MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
>CP022896.1|AXJ44333.1|2286104_2286899_-|tRNA-pseudouridine-synthase-A
MRILVEIAYQGNNFLGFQIQQNGRTVQQQFEKLLQRIHKRHVRIHPSSRTDRGVHAIQQYFHFDTDLNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFHCRYDCVGKRYRYKVYQAQQRDPFQSGLKTFIPEPLDLDKMNRAAQQFIGTHDFTGFCSQKTEVESKVRTLYQSEIVKTDDGFDYIVTGSGFLYNMVRVLVAFLIEVGKGRHEVSDVPKLLESKNRKNVPFTAPAEGLYLEKIYLDENELLKDFGNDIKIHRKKSL
>CP022896.1|AXJ44334.1|2286903_2287710_-|Energy-coupling-factor-transporter-transmembrane-protein-EcfT
MKNKLIIGRYLPINSFVHHLDPRAKLMFVFLFIILIFFCHSPLTYLWMFALILFFMRLAKIQLWFLIKGLTPIFFFLIFTLMMHIFLTKGGYVLVEWHGITIETNGILEGLYISLRLIGIVMIATIMTLSTSPIDLTDAFERLLAPLKMFKLPVHQLSMIMSIALRFIPTLMDELDKIILAQKSRGSEISSGNIATRIKSFIPLLVPLFISAFQRAEELAVAMEVRGYDANVKRTSYRQLKWQLRDTLSLIMIIPIAIILFVLKYSGV
>CP022896.1|AXJ44335.1|2287699_2288560_-|Energy-coupling-factor-transporter-ATP-binding-protein-EcfA2
MIIRFDNVSYTYQKGTPYQHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPVRKRIGMVFQFPESQLFEDTVEREMIFGPKNFKMNLDEAKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVVDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILISHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKEKLADWHIGLPEIVQLQYDFEQKHQTKLKDIALTEEAFVSLYKEWQHEK
>CP022896.1|AXJ44336.1|2288556_2289366_-|Energy-coupling-factor-transporter-ATP-binding-protein-EcfA1
MEDKNSVIVFKNVSFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKDIGIVFQNPDNQFVGSIVKYDVAFGLENHAVPHDEMHRRVSEALEQVDMLERADYEPNALSGGQKQRVAIASVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAMEADHVIVMNKGTVYKEGTATEIFDHAEELTTIGLDLPFPIKINQMLGHQTSFLTYEGLVDQL
>CP022896.1|AXJ44337.1|2289768_2290497_+|Transposase
MSIKPKVDIDVLLYMFQEYEKGVSFQYLIDTLQLDINVNTLYPKYKYYKTHGIETLLTQKQYNHYSKELKLKVVNEYLNSNQSTQDIAIKYNIRSSTQVKNWIKMYTVGKEIKNQSPKTGVYIMKARKTTFEERVTIVEYYLNHKQSYREVAEHFNISYGQIYQWVHKYQAHGKNGLVDGRGKGKPKSMMTPEEQKEAEIQALKAQNRLLEMENDVLKKFQALEREMIQRENKSRHTKRSKR
>CP022896.1|AXJ44338.1|2290520_2291309_+|Integrase-core-domain-protein
MCRILGISRASYYKWVHYQSSELELENEQLKREIESIYHKYNGIYGYRRIYIYIRLKLGKQVNRKRIYRLMKELNLKAVIRQKRKPYRRSTPQITSENKLNRQFDIDTPNKVWLTDVTEFKIKEGSKIYLSAIYDLGAKRIVSYELGPSNNNQLVFKTFNQAIEKVENTKGILFHSDRGFQYTSKTFKHMLDECGMIQSMSRVSKCIDNGPMEGVWGTIKSEIFRGNKHFKFNSVEEATKTIHDFILFFNHERITLKMADSV
>CP022896.1|AXJ44339.1|2291561_2291930_-|50S-ribosomal-protein-L17
MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV

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Crispr_ID: CP022896_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022896_7

2323046-2323126

Orphan

Consensus_repeat	Method
TCTATGTTGGGGCCCCGCCAACTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022896_7

>merge|CP022896|7|2323046-2323126|CRISPRCasFinder
TCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTTCGTCACCTTCTATGTTGGGGCCCCGCCAATTTG

>CP022896|7|5|2323046-2323126|CRISPRCasFinder
TCTATGTTGGGGCCCCGCCAACTTG	CACATTATTGTAAGCTGACTTTTCGTCACCT
TCTATGTTGGGGCCCCGCCAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
CP022896.1\|AXJ44375.1\|2313984_2314302_+\|hypothetical-protein	unknown	unknown	unknown
CP022896.1\|AXJ44388.1\|2326098_2327358_-\|Molybdopterin-molybdenumtransferase	unknown	unknown	gnl\|CDD\|238452
CP022896.1\|AXJ44387.1\|2325616_2326102_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-adapter-protein	unknown	unknown	gnl\|CDD\|224677
CP022896.1\|AXJ44383.1\|2323269_2324292_-\|Cyclic-pyranopterin-monophosphate-synthase	unknown	unknown	gnl\|CDD\|274250
CP022896.1\|AXJ44379.1\|2319669_2320434_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379203
CP022896.1\|AXJ44373.1\|2312534_2313443_-\|Membrane-transport-protein	unknown	unknown	gnl\|CDD\|223751
CP022896.1\|AXJ44385.1\|2324917_2325151_-\|Molybdopterin-synthase-sulfur-carrier-subunit	unknown	unknown	gnl\|CDD\|340452
CP022896.1\|AXJ44382.1\|2322342_2322693_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
CP022896.1\|AXJ44381.1\|2321119_2322241_+\|major-facilitator-superfamily-transporter	unknown	unknown	gnl\|CDD\|341042
CP022896.1\|AXJ44389.1\|2327420_2327915_+\|Cyclic-pyranopterin-monophosphate-synthase-accessory-protein	unknown	unknown	gnl\|CDD\|236483
CP022896.1\|AXJ44378.1\|2319426_2319678_+\|hypothetical-protein	unknown	unknown	unknown
CP022896.1\|AXJ44390.1\|2327916_2328423_-\|Molybdenum-cofactor-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|223595
CP022896.1\|AXJ44374.1\|2313575_2313740_+\|hypothetical-protein	unknown	unknown	unknown
CP022896.1\|AXJ44392.1\|2329623_2330229_-\|Sulfate/thiosulfate-import-ATP-binding-protein-CysA	unknown	unknown	gnl\|CDD\|226628
CP022896.1\|AXJ44384.1\|2324311_2324911_-\|putative-molybdenum-cofactor-guanylyltransferase	unknown	unknown	gnl\|CDD\|234725
CP022896.1\|AXJ44377.1\|2317772_2319038_-\|Lipid-II:glycine-glycyltransferase	unknown	unknown	gnl\|CDD\|225224
CP022896.1\|AXJ44386.1\|2325156_2325603_-\|Molybdopterin-synthase-catalytic-subunit	unknown	unknown	gnl\|CDD\|223391
CP022896.1\|AXJ44376.1\|2314488_2317656_-\|Swarming-motility-protein-SwrC	unknown	unknown	gnl\|CDD\|223911
CP022896.1\|AXJ44380.1\|2320596_2321037_+\|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
CP022896.1\|AXJ44391.1\|2328451_2329456_-\|Molybdopterin-synthase-adenylyltransferase	unknown	unknown	gnl\|CDD\|181084

Protein	Function_ID	Function_description	E-value
CP022896.1\|AXJ44388.1\|2326098_2327358_-\|Molybdopterin-molybdenumtransferase	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	7.37627e-158
CP022896.1\|AXJ44387.1\|2325616_2326102_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-adapter-protein	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	3.19119e-50
CP022896.1\|AXJ44383.1\|2323269_2324292_-\|Cyclic-pyranopterin-monophosphate-synthase	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
CP022896.1\|AXJ44379.1\|2319669_2320434_-\|hypothetical-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
CP022896.1\|AXJ44373.1\|2312534_2313443_-\|Membrane-transport-protein	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	5.74078e-43
CP022896.1\|AXJ44384.1\|2324311_2324911_-\|putative-molybdenum-cofactor-guanylyltransferase	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
CP022896.1\|AXJ44382.1\|2322342_2322693_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
CP022896.1\|AXJ44381.1\|2321119_2322241_+\|major-facilitator-superfamily-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.01335e-68
CP022896.1\|AXJ44389.1\|2327420_2327915_+\|Cyclic-pyranopterin-monophosphate-synthase-accessory-protein	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	1.48643e-96
CP022896.1\|AXJ44376.1\|2314488_2317656_-\|Swarming-motility-protein-SwrC	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
CP022896.1\|AXJ44390.1\|2327916_2328423_-\|Molybdenum-cofactor-biosynthesis-protein-B	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	2.50849e-64
CP022896.1\|AXJ44392.1\|2329623_2330229_-\|Sulfate/thiosulfate-import-ATP-binding-protein-CysA	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	1.03488e-114
CP022896.1\|AXJ44385.1\|2324917_2325151_-\|Molybdopterin-synthase-sulfur-carrier-subunit	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	2.40505e-24
CP022896.1\|AXJ44377.1\|2317772_2319038_-\|Lipid-II:glycine-glycyltransferase	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	2.47464e-141
CP022896.1\|AXJ44386.1\|2325156_2325603_-\|Molybdopterin-synthase-catalytic-subunit	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
CP022896.1\|AXJ44380.1\|2320596_2321037_+\|putative-HTH-type-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.16669e-15
CP022896.1\|AXJ44391.1\|2328451_2329456_-\|Molybdopterin-synthase-adenylyltransferase	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	4.64376e-130

>CP022896.1|AXJ44382.1|2322342_2322693_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>CP022896.1|AXJ44381.1|2321119_2322241_+|major-facilitator-superfamily-transporter
MYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGVIISLFIKVDFEVTNSKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFAIERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>CP022896.1|AXJ44380.1|2320596_2321037_+|putative-HTH-type-transcriptional-regulator
MLSQEFFNSFITIYRPYLKLTEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHNY
>CP022896.1|AXJ44379.1|2319669_2320434_-|hypothetical-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>CP022896.1|AXJ44378.1|2319426_2319678_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIALAIIHMGILAHSTYVYLY
>CP022896.1|AXJ44377.1|2317772_2319038_-|Lipid-II:glycine-glycyltransferase
MEKMHITNQEHDAFVKSNPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEIQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>CP022896.1|AXJ44376.1|2314488_2317656_-|Swarming-motility-protein-SwrC
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTSMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKTSASNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVTTIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKIDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>CP022896.1|AXJ44375.1|2313984_2314302_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>CP022896.1|AXJ44374.1|2313575_2313740_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>CP022896.1|AXJ44373.1|2312534_2313443_-|Membrane-transport-protein
MTEQFTMIILLIALGYFLKRINYIKATDSQVIATLVLNVTLPSLVIVNLNSAELKLSLSILPILMIIYGIVAKMIAVWFFRKYDNHMRGSVGMMTGAMNIGLFAYPLIEVIWPKTGLIYFGMADIGGAFVMFGITYFVGSYFSEGSDQFDFKYLGKKLLQSVPLVTYIVMFILNISHIHLPHVAIDFFSILSHANMPLSMILLGVMLNFTLERKYIPATIKYLCLHYGLALVAGLLVHVLLPVSDDMIKTTLLVTWMFPVGVAIISYGIQFKYRTLPFIGMTTNLTIIISIIILYVYQAVFV
>CP022896.1|AXJ44383.1|2323269_2324292_-|Cyclic-pyranopterin-monophosphate-synthase
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATADGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>CP022896.1|AXJ44384.1|2324311_2324911_-|putative-molybdenum-cofactor-guanylyltransferase
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>CP022896.1|AXJ44385.1|2324917_2325151_-|Molybdopterin-synthase-sulfur-carrier-subunit
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFENLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>CP022896.1|AXJ44386.1|2325156_2325603_-|Molybdopterin-synthase-catalytic-subunit
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>CP022896.1|AXJ44387.1|2325616_2326102_-|Molybdopterin-guanine-dinucleotide-biosynthesis-adapter-protein
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLTNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>CP022896.1|AXJ44388.1|2326098_2327358_-|Molybdopterin-molybdenumtransferase
MVVEKRNPIPVKEAIQRIVNQQSTMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETTTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQQDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>CP022896.1|AXJ44389.1|2327420_2327915_+|Cyclic-pyranopterin-monophosphate-synthase-accessory-protein
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIYKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFNWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLERKSGGKSGDFQRQLDQ
>CP022896.1|AXJ44390.1|2327916_2328423_-|Molybdenum-cofactor-biosynthesis-protein-B
MGEHQNVKLNRTVKAAVLTVSDTRNFDTDKGGQCVLQLLQVDNVEVSDAHYTIVKDEKVAITTQVKKWLEEDVDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNDKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>CP022896.1|AXJ44391.1|2328451_2329456_-|Molybdopterin-synthase-adenylyltransferase
MSQERYSRQILFKQIGEIGQNKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIDHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRTACTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENTSITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>CP022896.1|AXJ44392.1|2329623_2330229_-|Sulfate/thiosulfate-import-ATP-binding-protein-CysA
MLKINLKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP022896_1	1.1\|799185\|33\|CP022896\|CRISPRCasFinder	799185-799217	33	CP022896.1	1034447-1034479	1	0.97
CP022896_1	1.1\|799185\|33\|CP022896\|CRISPRCasFinder	799185-799217	33	CP022896.1	2358372-2358404	1	0.97
CP022896_7	7.1\|2323071\|31\|CP022896\|CRISPRCasFinder	2323071-2323101	31	CP022896.1	1060713-1060743	1	0.968
CP022896_7	7.1\|2323071\|31\|CP022896\|CRISPRCasFinder	2323071-2323101	31	CP022896.1	1633697-1633727	1	0.968
CP022896_2	2.1\|906742\|26\|CP022896\|CRISPRCasFinder	906742-906767	26	CP022896.1	2098746-2098771	2	0.923
CP022896_2	2.1\|906742\|26\|CP022896\|CRISPRCasFinder	906742-906767	26	CP022896.1	2158827-2158852	2	0.923
CP022896_4	4.1\|1978702\|37\|CP022896\|CRT	1978702-1978738	37	CP022896.1	812440-812476	2	0.946
CP022896_4	4.2\|1978760\|34\|CP022896\|CRT	1978760-1978793	34	CP022896.1	255915-255948	2	0.941
CP022896_4	4.2\|1978760\|34\|CP022896\|CRT	1978760-1978793	34	CP022896.1	330672-330705	2	0.941
CP022896_4	4.2\|1978760\|34\|CP022896\|CRT	1978760-1978793	34	CP022896.1	766020-766053	2	0.941
CP022896_4	4.2\|1978760\|34\|CP022896\|CRT	1978760-1978793	34	CP022896.1	799224-799257	2	0.941
CP022896_4	4.2\|1978760\|34\|CP022896\|CRT	1978760-1978793	34	CP022896.1	1060650-1060683	2	0.941
CP022896_4	4.2\|1978760\|34\|CP022896\|CRT	1978760-1978793	34	CP022896.1	1754689-1754722	2	0.941
CP022896_4	4.2\|1978760\|34\|CP022896\|CRT	1978760-1978793	34	CP022896.1	2323010-2323043	2	0.941
CP022896_4	4.2\|1978760\|34\|CP022896\|CRT	1978760-1978793	34	CP022896.1	2466124-2466157	2	0.941
CP022896_7	7.1\|2323071\|31\|CP022896\|CRISPRCasFinder	2323071-2323101	31	CP022896.1	812564-812594	2	0.935
CP022896_7	7.1\|2323071\|31\|CP022896\|CRISPRCasFinder	2323071-2323101	31	CP022896.1	861873-861903	2	0.935
CP022896_7	7.1\|2323071\|31\|CP022896\|CRISPRCasFinder	2323071-2323101	31	CP022896.1	906703-906733	2	0.935
CP022896_7	7.1\|2323071\|31\|CP022896\|CRISPRCasFinder	2323071-2323101	31	CP022896.1	1968144-1968174	2	0.935

1. spacer 1.1|799185|33|CP022896|CRISPRCasFinder matches to position: 1034447-1034479, mismatch: 1, identity: 0.97

attgggaatccaatttctctttgttggggccca	CRISPR spacer
attgggaatccaatttctctgtgttggggccca	Protospacer
******************** ************

2. spacer 1.1|799185|33|CP022896|CRISPRCasFinder matches to position: 2358372-2358404, mismatch: 1, identity: 0.97

attgggaatccaatttctctttgttggggccca	CRISPR spacer
attgggaatccaatttctctttgttgggaccca	Protospacer
****************************.****

3. spacer 7.1|2323071|31|CP022896|CRISPRCasFinder matches to position: 1060713-1060743, mismatch: 1, identity: 0.968

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**************************** **

4. spacer 7.1|2323071|31|CP022896|CRISPRCasFinder matches to position: 1633697-1633727, mismatch: 1, identity: 0.968

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**************************** **

5. spacer 2.1|906742|26|CP022896|CRISPRCasFinder matches to position: 2098746-2098771, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggtgg	CRISPR spacer
cgcggccccaacacagaagctggcgg	Protospacer
** ********************.**

6. spacer 2.1|906742|26|CP022896|CRISPRCasFinder matches to position: 2158827-2158852, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggtgg	CRISPR spacer
cggggccccaacacaaaagctggcgg	Protospacer
***************.*******.**

7. spacer 4.1|1978702|37|CP022896|CRT matches to position: 812440-812476, mismatch: 2, identity: 0.946

ccaacttgcacattattgtaagctgacagaaagtcag	CRISPR spacer
ccaacttgcacattattgtaagctggcggaaagtcag	Protospacer
*************************.*.*********

8. spacer 4.2|1978760|34|CP022896|CRT matches to position: 255915-255948, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgcctgtagaatttcttttcgaaat	Protospacer
***********.************.*********

9. spacer 4.2|1978760|34|CP022896|CRT matches to position: 330672-330705, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtttgtagaatttcttttcgaaat	Protospacer
************.***********.*********

10. spacer 4.2|1978760|34|CP022896|CRT matches to position: 766020-766053, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtttgtagaatttcttttcgaaat	Protospacer
************.***********.*********

11. spacer 4.2|1978760|34|CP022896|CRT matches to position: 799224-799257, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgcctgtagaatttcttttcgaaat	Protospacer
***********.************.*********

12. spacer 4.2|1978760|34|CP022896|CRT matches to position: 1060650-1060683, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgcctgtagaatttcttttcgaaat	Protospacer
***********.************.*********

13. spacer 4.2|1978760|34|CP022896|CRT matches to position: 1754689-1754722, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtctgtagaatttctttttgaaat	Protospacer
************************.***.*****

14. spacer 4.2|1978760|34|CP022896|CRT matches to position: 2323010-2323043, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtctgtagaatttctttttgaaat	Protospacer
************************.***.*****

15. spacer 4.2|1978760|34|CP022896|CRT matches to position: 2466124-2466157, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtctgtagaatttctttttgaaat	Protospacer
************************.***.*****

16. spacer 7.1|2323071|31|CP022896|CRISPRCasFinder matches to position: 812564-812594, mismatch: 2, identity: 0.935

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctgactttacgtcagct	Protospacer
********************** ***** **

17. spacer 7.1|2323071|31|CP022896|CRISPRCasFinder matches to position: 861873-861903, mismatch: 2, identity: 0.935

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctggcttttcgtcagct	Protospacer
*****************.********** **

18. spacer 7.1|2323071|31|CP022896|CRISPRCasFinder matches to position: 906703-906733, mismatch: 2, identity: 0.935

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctgacttttcgccagct	Protospacer
*************************.** **

19. spacer 7.1|2323071|31|CP022896|CRISPRCasFinder matches to position: 1968144-1968174, mismatch: 2, identity: 0.935

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattatcgtaagctgacttttcgtcagct	Protospacer
********.******************* **

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

354181 : 370046

Staphylococcus_phage(76.19%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ42595.1\|354181_354373_-	hypothetical protein	U3PCX8	Staphylococcus_phage	4.9e-23	80.0
AXJ42596.1\|354616_354913_+	30S ribosomal protein S6	NA	NA	NA	NA
AXJ42597.1\|354933_355437_+	Single-stranded DNA-binding protein ssb	A0A1W6JPL9	Staphylococcus_phage	1.2e-60	74.7
AXJ42598.1\|355488_355731_+	30S ribosomal protein S18	NA	NA	NA	NA
AXJ42599.1\|355962_356682_-	PemK-like protein	Q4ZE81	Staphylococcus_phage	3.7e-23	29.8
AXJ42600.1\|356794_358009_-	Tyrosine recombinase XerD	Q4ZE80	Staphylococcus_phage	3.3e-221	97.3
AXJ42601.1\|358283_359003_-	Helix-turn-helix domain protein	Q4ZE79	Staphylococcus_phage	1.4e-17	30.6
AXJ42602.1\|359188_359401_+	Helix-turn-helix domain protein	Q4ZE78	Staphylococcus_phage	8.9e-26	80.0
AXJ42603.1\|359401_359674_+	hypothetical protein	Q4ZE77	Staphylococcus_phage	4.2e-44	96.7
AXJ42604.1\|359685_359832_+	hypothetical protein	NA	NA	NA	NA
AXJ42605.1\|359824_360037_+	hypothetical protein	A0A1W6JPA6	Staphylococcus_phage	1.7e-16	70.6
AXJ42606.1\|360038_360398_+	hypothetical protein	NA	NA	NA	NA
AXJ42607.1\|360398_360719_+	hypothetical protein	Q4ZE75	Staphylococcus_phage	3.8e-20	50.9
AXJ42608.1\|360782_361652_+	hypothetical protein	A0A2H4JEH3	uncultured_Caudovirales_phage	2.7e-132	76.5
AXJ42609.1\|361663_363034_+	hypothetical protein	A0A2H4JBE3	uncultured_Caudovirales_phage	1.0e-255	94.5
AXJ42610.1\|363351_363633_+	hypothetical protein	A0A2H4JBD4	uncultured_Caudovirales_phage	5.5e-39	79.6
AXJ42611.1\|363634_363898_+	hypothetical protein	NA	NA	NA	NA
AXJ42612.1\|363899_364541_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	5.0e-112	94.8
AXJ42613.1\|365076_365418_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	2.9e-58	100.0
AXJ42614.1\|365448_366102_+	hypothetical protein	Q4ZE82	Staphylococcus_phage	7.6e-116	99.5
AXJ42615.1\|366154_366682_+	hypothetical protein	Q4ZE87	Staphylococcus_phage	6.8e-91	100.0
AXJ42616.1\|366684_367026_+	hypothetical protein	Q4ZE86	Staphylococcus_phage	1.1e-57	98.2
AXJ42617.1\|367022_367592_+	Terminase small subunit	Q4ZE85	Staphylococcus_phage	4.6e-101	98.4
AXJ42618.1\|367868_368837_+	Abi-like protein	A0A0H4U080	Erysipelothrix_phage	2.7e-24	27.3
AXJ42619.1\|369014_369416_+	hypothetical protein	A0A2H4J577	uncultured_Caudovirales_phage	5.1e-22	59.1
AXJ42620.1\|369533_370046_+	hypothetical protein	Q4ZE83	Staphylococcus_phage	1.4e-69	100.0

DBSCAN-SWA_2

744401 : 752221

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ42954.1\|744401_745457_-	Histidine protein kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
AXJ42955.1\|745456_746143_-	Response regulator SaeR	NA	NA	NA	NA
AXJ42956.1\|746117_746591_-	DoxX	NA	NA	NA	NA
AXJ42957.1\|746932_747373_-	Electron transfer DM13	NA	NA	NA	NA
AXJ42958.1\|747652_748237_-	hypothetical protein	NA	NA	NA	NA
AXJ42959.1\|748335_749049_-	7-carboxy-7-deazaguanine synthase	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
AXJ42960.1\|749052_749472_-	6-carboxy-5,6,7,8-tetrahydropterin synthase	S4U060	uncultured_phage	6.3e-07	28.7
AXJ42961.1\|749473_750142_-	7-cyano-7-deazaguanine synthase	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
AXJ42962.1\|750492_751086_+	Anthranilate synthase component 2	A0A0P0IKJ1	Acinetobacter_phage	8.9e-39	44.0
AXJ42963.1\|751069_752221_+	Aminodeoxychorismate synthase component 1	S4VNU7	Pandoravirus	2.1e-23	36.1

DBSCAN-SWA_3

764193 : 778331

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ42972.1\|764193_765252_+	Histidinol-phosphate aminotransferase	A0A0H3TLT9	Faustovirus	5.7e-20	26.5
AXJ42973.1\|765410_765953_+	Putative 5'(3')-deoxyribonucleotidase	NA	NA	NA	NA
AXJ42974.1\|765957_766092_+	hypothetical protein	NA	NA	NA	NA
AXJ42975.1\|766504_767422_-	Putative lipid kinase	A0A1V0SBJ0	Catovirus	8.2e-07	22.0
AXJ42976.1\|767691_769197_-	Di-/tripeptide transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
AXJ42977.1\|769536_770037_-	NADPH-dependent 7-cyano-7-deazaguanine reductase	E7DN65	Pneumococcus_phage	2.7e-52	66.2
AXJ42978.1\|770056_770923_-	EamA-like transporter family protein	NA	NA	NA	NA
AXJ42979.1\|771724_772123_+	ribonucleotide reductase stimulatory protein	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
AXJ42980.1\|772085_774191_+	Ribonucleoside-diphosphate reductase subunit alpha 2	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
AXJ42981.1\|774310_775282_+	Ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
AXJ42982.1\|775658_776630_+	Fe(3+) dicitrate transport system permease protein FecD	A0A2H4IY97	uncultured_Caudovirales_phage	7.8e-141	80.2
AXJ42983.1\|776616_777573_+	Iron-uptake system permease protein FeuC	A0A2H4J116	uncultured_Caudovirales_phage	5.5e-06	60.0
AXJ42984.1\|777569_778331_+	putative siderophore transport system ATP-binding protein YusV	Q9EMR9	Amsacta_moorei_entomopoxvirus	7.2e-17	30.1

DBSCAN-SWA_4

1605317 : 1613629

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ43717.1\|1605317_1606103_-	High-affinity zinc uptake system ATP-binding protein ZnuC	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
AXJ43718.1\|1606228_1607119_-	putative endonuclease 4	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
AXJ43719.1\|1607128_1608475_-	DEAD-box ATP-dependent RNA helicase CshB	A0A1V0SIR5	Klosneuvirus	1.4e-55	34.0
AXJ43720.1\|1608588_1609689_-	Putative GTP cyclohydrolase 1 type 2	A0A1S5V250	Saudi_moumouvirus	3.0e-08	30.6
AXJ43721.1\|1609691_1610369_-\|tRNA	tRNA (adenine(22)-N(1))-methyltransferase	NA	NA	NA	NA
AXJ43722.1\|1610499_1611606_-	RNA polymerase sigma factor SigA	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
AXJ43723.1\|1611829_1613629_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.5e-54	36.0

DBSCAN-SWA_5

1683071 : 1692114

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ43791.1\|1683071_1683590_-	Adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
AXJ43792.1\|1683611_1685885_-	Single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	6.2e-64	29.3
AXJ43793.1\|1686087_1688367_-	bifunctional preprotein translocase subunit SecD/SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
AXJ43794.1\|1688641_1688902_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
AXJ43795.1\|1688920_1690060_-\|tRNA	Queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
AXJ43796.1\|1690082_1691108_-\|tRNA	S-adenosylmethionine:tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
AXJ43797.1\|1691109_1692114_-	Holliday junction ATP-dependent DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_6

1822916 : 1892897

Staphylococcus_phage(90.91%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ43905.1\|1822916_1829486_-	Extracellular matrix-binding protein ebh precursor	A0A2H4PQU6	Staphylococcus_phage	1.7e-295	88.7
AXJ43906.1\|1829809_1830121_-	molybdopterin biosynthesis protein MoeB	A0A2H4PQR9	Staphylococcus_phage	4.5e-50	96.1
AXJ43907.1\|1830142_1832560_-\|tRNA	Leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	98.7
AXJ43908.1\|1832848_1834030_-	Multidrug resistance protein MdtH	A0A2H4PQR6	Staphylococcus_phage	9.6e-218	99.7
AXJ43909.1\|1834140_1835094_+	coproporphyrinogen III oxidase	A0A2H4PQV5	Staphylococcus_phage	6.4e-79	99.3
AXJ43910.1\|1835090_1835654_+	16S rRNA m(4)C1402 methyltransferase	A0A2H4PQV0	Staphylococcus_phage	1.1e-99	95.7
AXJ43911.1\|1835772_1836174_-	HTH-type transcriptional regulator rot	NA	NA	NA	NA
AXJ43912.1\|1836746_1837574_-	Phospholipase YtpA	NA	NA	NA	NA
AXJ43913.1\|1837807_1838809_+	Proline dehydrogenase 1	A0A2H4PQT6	Staphylococcus_phage	5.0e-183	99.1
AXJ43914.1\|1838930_1839395_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.9e-68	97.4
AXJ43915.1\|1839407_1840589_-	Riboflavin biosynthesis protein RibBA	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
AXJ43916.1\|1840599_1841232_-	Riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	8.4e-112	99.0
AXJ43917.1\|1841238_1842282_-	Riboflavin biosynthesis protein RibD	A0A2H4PQS8	Staphylococcus_phage	5.9e-195	98.3
AXJ43918.1\|1842762_1844265_-	hypothetical protein	A0A2H4PQX2	Staphylococcus_phage	5.0e-30	98.6
AXJ43919.1\|1844907_1845222_+	Transcriptional repressor SdpR	A0A2H4PQT4	Staphylococcus_phage	1.7e-52	97.1
AXJ43920.1\|1845221_1846514_+	Arsenical pump membrane protein	A0A2H4PQU3	Staphylococcus_phage	2.6e-216	95.1
AXJ43921.1\|1846600_1847455_-	Bifunctional autolysin precursor	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
AXJ43922.1\|1847730_1847955_-	hypothetical protein	NA	NA	NA	NA
AXJ43923.1\|1848509_1849457_+	Integrase core domain protein	Q9MBM9	Staphylococcus_prophage	1.1e-184	100.0
AXJ43924.1\|1849810_1850254_+	hypothetical protein	NA	NA	NA	NA
AXJ43925.1\|1850240_1850684_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-49	77.4
AXJ43926.1\|1850981_1851617_+\|protease	CAAX amino terminal protease self- immunity	NA	NA	NA	NA
AXJ43927.1\|1851783_1852404_+\|protease	CAAX amino terminal protease self- immunity	NA	NA	NA	NA
AXJ43928.1\|1852861_1853575_-	Transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
AXJ43929.1\|1853833_1854136_+	hypothetical protein	NA	NA	NA	NA
AXJ43930.1\|1854390_1854756_+	Putative fluoride ion transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
AXJ43931.1\|1854752_1855106_+	Putative fluoride ion transporter CrcB	A0A2H4PQQ7	Staphylococcus_phage	4.2e-20	97.4
AXJ43932.1\|1855355_1856189_-	Glyoxal reductase	A0A2H4PQR8	Staphylococcus_phage	1.2e-158	99.6
AXJ43933.1\|1856400_1857309_-	hypothetical protein	A0A2H4PQQ8	Staphylococcus_phage	9.8e-138	99.7
AXJ43934.1\|1857433_1858627_-	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	4.3e-218	99.5
AXJ43935.1\|1858998_1860591_+	Phosphoenolpyruvate carboxykinase [ATP]	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
AXJ43936.1\|1860883_1861654_-	Prolyl oligopeptidase family protein	A0A2H4PQM6	Staphylococcus_phage	3.4e-139	97.2
AXJ43937.1\|1861634_1862114_-	Putative 8-oxo-dGTP diphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	3.0e-85	98.7
AXJ43938.1\|1862173_1862431_+	Putative membrane protein insertion efficiency factor	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
AXJ43939.1\|1862427_1863429_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	8.5e-183	96.7
AXJ43940.1\|1863433_1864912_-	2-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.4e-282	97.2
AXJ43941.1\|1865070_1865553_-	hypothetical protein	A0A2H4PQN7	Staphylococcus_phage	2.8e-75	94.5
AXJ43942.1\|1865863_1866478_+	SPBc2 prophage-derived endonuclease YokF precursor	A0A2H4PQM8	Staphylococcus_phage	3.6e-43	87.3
AXJ43943.1\|1866558_1867554_+	Telomeric repeat-binding factor 2	A0A2H4PQN2	Staphylococcus_phage	3.8e-74	97.2
AXJ43944.1\|1867629_1868256_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	4.5e-81	84.1
AXJ43945.1\|1868296_1868641_+	hypothetical protein	A0A2H4PQN6	Staphylococcus_phage	5.1e-55	94.7
AXJ43946.1\|1868738_1869311_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	3.2e-25	94.8
AXJ43947.1\|1869459_1870827_-	FRG domain protein	NA	NA	NA	NA
AXJ43948.1\|1870826_1871396_-	hypothetical protein	A0A2H4PQN8	Staphylococcus_phage	2.2e-39	54.8
AXJ43949.1\|1871588_1872035_-	hypothetical protein	NA	NA	NA	NA
AXJ43950.1\|1872116_1872341_-	hypothetical protein	NA	NA	NA	NA
AXJ43951.1\|1872979_1873423_-	hypothetical protein	NA	NA	NA	NA
AXJ43952.1\|1873422_1873866_-	hypothetical protein	NA	NA	NA	NA
AXJ43953.1\|1873865_1874186_-	hypothetical protein	NA	NA	NA	NA
AXJ43954.1\|1874832_1877253_+	Hyaluronate lyase precursor	NA	NA	NA	NA
AXJ43955.1\|1877378_1877756_-	hypothetical protein	NA	NA	NA	NA
AXJ43956.1\|1877965_1878415_-	hypothetical protein	NA	NA	NA	NA
AXJ43957.1\|1878457_1880068_+	hypothetical protein	NA	NA	NA	NA
AXJ43958.1\|1880082_1880382_+	hypothetical protein	NA	NA	NA	NA
AXJ43959.1\|1880643_1882461_-	hypothetical protein	NA	NA	NA	NA
AXJ43960.1\|1882497_1883652_-	Type I restriction modification DNA specificity domain protein	A0A2H4PQP5	Staphylococcus_phage	7.8e-39	36.3
AXJ43961.1\|1883644_1885201_-	Type I restriction enzyme EcoKI M protein	A0A2H4PQP4	Staphylococcus_phage	2.2e-286	98.6
AXJ43962.1\|1885563_1886283_-\|protease	Serine protease SplF precursor	A0A2H4PQP1	Staphylococcus_phage	1.0e-129	98.3
AXJ43963.1\|1886452_1887169_-\|protease	Serine protease SplE precursor	A0A2H4PQN5	Staphylococcus_phage	6.6e-129	97.1
AXJ43964.1\|1888214_1888931_-\|protease	Serine protease SplE precursor	A0A2H4PQN5	Staphylococcus_phage	5.5e-83	62.6
AXJ43965.1\|1889054_1889774_-\|protease	Serine protease SplC precursor	A0A2H4PQP7	Staphylococcus_phage	6.4e-124	93.7
AXJ43966.1\|1889831_1889996_-\|protease	Serine protease SplB precursor	A0A2H4PQN0	Staphylococcus_phage	5.9e-17	97.7
AXJ43967.1\|1890074_1890320_+	hypothetical protein	NA	NA	NA	NA
AXJ43968.1\|1890788_1891304_+	hypothetical protein	NA	NA	NA	NA
AXJ43969.1\|1891550_1892897_+	hypothetical protein	M1NRY5	Streptococcus_phage	2.5e-65	51.1

DBSCAN-SWA_7

2024154 : 2071461

Staphylococcus_phage(100.0%)

tail,protease,portal,holin,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ44085.1\|2024154_2024355_+	Phospholipase C precursor	A0A1P8L6A7	Staphylococcus_phage	4.9e-26	95.4
AXJ44086.1\|2025529_2025880_-	Complement inhibitor precursor	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
AXJ44087.1\|2026565_2027015_+	Chemotaxis inhibitory protein precursor	A0A1P8L6A8	Staphylococcus_phage	1.1e-78	100.0
AXJ44088.1\|2027109_2027406_-	Bacterial SH3 domain protein	A0A1P8L6B4	Staphylococcus_phage	1.3e-51	100.0
AXJ44089.1\|2028094_2028586_-	Staphylokinase precursor	A0A1X9H028	Staphylococcus_phage	9.5e-87	100.0
AXJ44090.1\|2028776_2029532_-	putative cell wall hydrolase LytN precursor	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
AXJ44091.1\|2029543_2029798_-\|holin	Bacteriophage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
AXJ44092.1\|2030294_2031068_-	Enterotoxin type A precursor	A0EX09	Staphylococcus_phage	2.2e-146	100.0
AXJ44093.1\|2031488_2031863_-	hypothetical protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
AXJ44094.1\|2031918_2032206_-	hypothetical protein	G4KNR2	Staphylococcus_phage	9.9e-44	100.0
AXJ44095.1\|2032252_2032405_-	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
AXJ44096.1\|2032394_2036180_-	hypothetical protein	A0EX05	Staphylococcus_phage	0.0e+00	100.0
AXJ44097.1\|2036195_2037680_-\|tail	Phage tail protein	A0EX04	Staphylococcus_phage	4.5e-297	100.0
AXJ44098.1\|2037676_2042206_-	Murein DD-endopeptidase MepM	A0EX03	Staphylococcus_phage	0.0e+00	100.0
AXJ44099.1\|2042262_2042400_-	hypothetical protein	A0A2I6PDX7	Staphylococcus_phage	3.4e-18	100.0
AXJ44100.1\|2042450_2042801_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
AXJ44101.1\|2043116_2043761_-	hypothetical protein	A0EWZ9	Staphylococcus_phage	3.8e-120	100.0
AXJ44102.1\|2043761_2044169_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
AXJ44103.1\|2044165_2044570_-	hypothetical protein	G4KNQ5	Staphylococcus_phage	4.3e-69	100.0
AXJ44104.1\|2044566_2044929_-	hypothetical protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
AXJ44105.1\|2044912_2045197_-	hypothetical protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
AXJ44106.1\|2045186_2045471_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
AXJ44107.1\|2045490_2046636_-\|capsid	Phage capsid family protein	G4KNQ3	Staphylococcus_phage	9.6e-215	100.0
AXJ44108.1\|2046659_2047397_-\|protease	ATP-dependent Clp protease proteolytic subunit	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
AXJ44109.1\|2047380_2048568_-\|portal	Phage portal protein	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
AXJ44110.1\|2048583_2050245_-	Phage Terminase	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
AXJ44111.1\|2050241_2050586_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
AXJ44112.1\|2050715_2051015_-	HNH endonuclease	A0EWY8	Staphylococcus_phage	4.6e-52	100.0
AXJ44113.1\|2051246_2051663_-	hypothetical protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
AXJ44114.1\|2051690_2051891_-	hypothetical protein	A0A2I6PDV9	Staphylococcus_phage	1.4e-28	100.0
AXJ44115.1\|2051890_2052040_-	Transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
AXJ44116.1\|2052036_2052423_-	hypothetical protein	W5R986	Staphylococcus_phage	3.0e-64	100.0
AXJ44117.1\|2052419_2052626_-	hypothetical protein	A0A0H3U2R7	Staphylococcus_phage	1.3e-29	100.0
AXJ44118.1\|2052662_2053205_-	Deoxyuridine 5'-triphosphate nucleotidohydrolase	A0EWY2	Staphylococcus_phage	1.1e-96	100.0
AXJ44119.1\|2053197_2053380_-	hypothetical protein	A0EWY1	Staphylococcus_phage	2.6e-26	100.0
AXJ44120.1\|2053369_2053621_-	hypothetical protein	A0EWY0	Staphylococcus_phage	1.9e-38	100.0
AXJ44121.1\|2053613_2053778_-	hypothetical protein	A0EWX9	Staphylococcus_phage	1.7e-24	100.0
AXJ44122.1\|2053792_2054035_-	hypothetical protein	A0EWX8	Staphylococcus_phage	3.9e-41	100.0
AXJ44123.1\|2054038_2054407_-	PVL ORF-50-like family protein	W5RAK8	Staphylococcus_phage	8.2e-51	100.0
AXJ44124.1\|2054519_2054729_-	hypothetical protein	A0EWX6	Staphylococcus_phage	3.1e-31	98.5
AXJ44125.1\|2054737_2054956_-	hypothetical protein	A0A2I6PDG4	Staphylococcus_phage	1.2e-36	98.6
AXJ44126.1\|2054962_2055847_-	Replication initiation and membrane attachment	A0EWX4	Staphylococcus_phage	5.4e-141	100.0
AXJ44127.1\|2055876_2056347_-	Single-stranded DNA-binding protein ssb	A0EWX3	Staphylococcus_phage	7.4e-81	100.0
AXJ44128.1\|2056347_2056833_-	Beta-lactamase superfamily domain protein	S4SWA4	Staphylococcus_phage	9.4e-87	100.0
AXJ44129.1\|2057045_2057966_-	recombination and repair protein RecT	S4SUN6	Staphylococcus_phage	2.3e-166	100.0
AXJ44130.1\|2057967_2059911_-	hypothetical protein	A0EWX0	Staphylococcus_phage	0.0e+00	100.0
AXJ44131.1\|2059919_2060183_-	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
AXJ44132.1\|2060191_2060455_-	hypothetical protein	A0EWW8	Staphylococcus_phage	9.0e-44	100.0
AXJ44133.1\|2060432_2060759_-	hypothetical protein	W5RAK4	Staphylococcus_phage	1.2e-53	100.0
AXJ44134.1\|2060853_2061015_-	hypothetical protein	D2JGJ6	Staphylococcus_phage	4.3e-20	100.0
AXJ44135.1\|2061011_2061332_-	hypothetical protein	A0A2I6PDH6	Staphylococcus_phage	1.5e-56	100.0
AXJ44136.1\|2061390_2062023_+	hypothetical protein	A7TW95	Staphylococcus_phage	1.5e-113	100.0
AXJ44137.1\|2062037_2062178_-	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	1.9e-16	100.0
AXJ44138.1\|2062208_2062406_-	hypothetical protein	Q8SDM8	Staphylococcus_phage	7.0e-33	100.0
AXJ44139.1\|2062421_2063174_-	Phage antirepressor protein KilAC domain protein	M9NTH5	Staphylococcus_phage	1.1e-139	100.0
AXJ44140.1\|2063224_2063554_+	hypothetical protein	M9NS98	Staphylococcus_phage	2.7e-53	100.0
AXJ44141.1\|2063542_2063758_-	hypothetical protein	A0EWV9	Staphylococcus_phage	6.3e-35	100.0
AXJ44142.1\|2063773_2064037_-	helix-turn-helix protein	A0A2I6PF09	Staphylococcus_phage	7.2e-41	100.0
AXJ44143.1\|2064169_2064883_+	LexA repressor	M9NUL0	Staphylococcus_phage	1.2e-130	100.0
AXJ44144.1\|2064898_2065831_+	DNA polymerase III subunit epsilon	A0A2I6PEZ7	Staphylococcus_phage	5.7e-173	100.0
AXJ44145.1\|2065836_2066178_+	hypothetical protein	A0A2I6PF04	Staphylococcus_phage	4.6e-56	100.0
AXJ44146.1\|2066381_2066564_+	hypothetical protein	M9NSW6	Staphylococcus_phage	4.1e-27	100.0
AXJ44147.1\|2066663_2067128_+	hypothetical protein	A0EWV3	Staphylococcus_phage	1.1e-28	100.0
AXJ44148.1\|2067186_2068224_+	Tyrosine recombinase XerC	A0EWV2	Staphylococcus_phage	9.1e-180	100.0
AXJ44149.1\|2068280_2069108_+	Phospholipase C precursor	A0A1P8L6H7	Staphylococcus_phage	3.5e-158	98.9
AXJ44150.1\|2069364_2070384_-	putative leukocidin-like protein 1 precursor	A0A2I6PEU3	Staphylococcus_phage	3.4e-54	39.6
AXJ44151.1\|2070405_2071461_-	putative leukocidin-like protein 2 precursor	A0A2I6PER8	Staphylococcus_phage	7.9e-38	34.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP022896

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection