CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP025838	Streptococcus pneumoniae strain SPN XDR SMC1710-32 chromosome, complete genome	3 crisprs	cas3,DinG,DEDDh,RT	0	1	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP025838_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025838_1

11476-11577

Unclear

Consensus_repeat	Method
GTTGTTTCTTATACAGTTTTTCTTG	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of CP025838_1

>merge|CP025838|1|11476-11577|CRISPRCasFinder
GTTGTTTCTTATACAGTTTTTCTTGCCTACAGCCTCATGCTCTCGGTCGCCAAACTTCTGAGCGTGGGGCTTTTTGAGTTGTTTCTTATACAGTTTTTTCTT

>CP025838|1|1|11476-11577|CRISPRCasFinder
GTTGTTTCTTATACAGTTTTTCTTG	CCTACAGCCTCATGCTCTCGGTCGCCAAACTTCTGAGCGTGGGGCTTTTTGA
GTTGTTTCTTATACAGTTTTTTCTT

Protein	Signature genes	Signature genes Name	Protein_function
CP025838.1\|AXJ87480.1\|9610_9886_-\|hypothetical-protein	unknown	unknown	unknown
CP025838.1\|AXJ87481.1\|9878_10220_-\|DNA-binding-protein	unknown	unknown	unknown
CP025838.1\|AXJ87485.1\|11808_12435_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226172
CP025838.1\|AXJ87486.1\|12524_12758_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376540
CP025838.1\|AXJ89366.1\|7088_8558_-\|DNA-primase	unknown	unknown	gnl\|CDD\|273716
CP025838.1\|AXJ87488.1\|14019_15024_+\|DNA-binding-protein	unknown	unknown	unknown
CP025838.1\|AXJ87492.1\|18043_18613_+\|peptidyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|223271
CP025838.1\|AXJ87494.1\|22205_22472_+\|RNA-binding-S4-domain-containing-protein	unknown	unknown	gnl\|CDD\|224109
CP025838.1\|AXJ87479.1\|4834_5044_+\|hypothetical-protein	unknown	unknown	unknown
CP025838.1\|AXJ89368.1\|10904_11300_-\|hypothetical-protein	unknown	unknown	unknown
CP025838.1\|AXJ87491.1\|16857_17973_+\|redox-regulated-ATPase-YchF	unknown	unknown	gnl\|CDD\|236583
CP025838.1\|AXJ87483.1\|10490_10706_-\|hypothetical-protein	unknown	unknown	unknown
CP025838.1\|AXJ89367.1\|8610_9471_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|214926
CP025838.1\|AXJ87487.1\|12914_13871_+\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP025838.1\|AXJ87484.1\|10707_10908_-\|hypothetical-protein	unknown	unknown	unknown
CP025838.1\|AXJ87493.1\|18613_22138_+\|transcription-repair-coupling-factor	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224118
CP025838.1\|AXJ87489.1\|15023_15476_+\|type-II-toxin-antitoxin-system-death-on-curing-family-toxin	unknown	unknown	gnl\|CDD\|226180
CP025838.1\|AXJ87478.1\|4707_4923_-\|hypothetical-protein	unknown	unknown	unknown
CP025838.1\|AXJ87482.1\|10200_10494_-\|hypothetical-protein	unknown	unknown	unknown
CP025838.1\|AXJ87490.1\|15571_16738_+\|tyrosine-recombinase-XerS	unknown	unknown	gnl\|CDD\|271189

Protein	Function_ID	Function_description	E-value
CP025838.1\|AXJ87491.1\|16857_17973_+\|redox-regulated-ATPase-YchF	gnl\|CDD\|236583	PRK09601, PRK09601, redox-regulated ATPase YchF.	0
CP025838.1\|AXJ89367.1\|8610_9471_-\|hypothetical-protein	gnl\|CDD\|214926	smart00942, PriCT_1, Primase C terminal 1 (PriCT-1). This alpha helical domain is found at the C terminal of primases.	2.9188e-17
CP025838.1\|AXJ87485.1\|11808_12435_-\|hypothetical-protein	gnl\|CDD\|226172	COG3646, COG3646, Uncharacterized phage-encoded protein [Function unknown].	3.14309e-37
CP025838.1\|AXJ87486.1\|12524_12758_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|376540	pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within Neisseria gonorrhoeae NGO_0477, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family.	1.78307e-08
CP025838.1\|AXJ87494.1\|22205_22472_+\|RNA-binding-S4-domain-containing-protein	gnl\|CDD\|224109	COG1188, COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) [Translation, ribosomal structure and biogenesis].	4.06015e-32
CP025838.1\|AXJ89366.1\|7088_8558_-\|DNA-primase	gnl\|CDD\|273716	TIGR01613, putative_primase, phage/plasmid primase, P4 family, C-terminal domain. This model represents a clade within a larger family of proteins from viruses of bacteria and animals. Members of this family are found in phage and plasmids of bacteria and archaea only. The model describes a domain of about 300 residues, found generally toward the protein C-terminus. [DNA metabolism, DNA replication, recombination, and repair, Mobile and extrachromosomal element functions, Prophage functions].	4.85429e-65
CP025838.1\|AXJ87493.1\|18613_22138_+\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0
CP025838.1\|AXJ87489.1\|15023_15476_+\|type-II-toxin-antitoxin-system-death-on-curing-family-toxin	gnl\|CDD\|226180	COG3654, Doc, Prophage maintenance system killer protein [General function prediction only].	3.22826e-08
CP025838.1\|AXJ87492.1\|18043_18613_+\|peptidyl-tRNA-hydrolase	gnl\|CDD\|223271	COG0193, Pth, Peptidyl-tRNA hydrolase [Translation, ribosomal structure and biogenesis].	3.56215e-98
CP025838.1\|AXJ87487.1\|12914_13871_+\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.10008e-08
CP025838.1\|AXJ87490.1\|15571_16738_+\|tyrosine-recombinase-XerS	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.91623e-44

>CP025838.1|AXJ89368.1|10904_11300_-|hypothetical-protein
MQEIGEKNGLSRLSLLASQTKFIKEELSRLLWIELPELNDSHKIEAVSKSTTGMFFHPGIFEMDAMRQAFFKRQAMHFFENEAEQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ
>CP025838.1|AXJ87484.1|10707_10908_-|hypothetical-protein
MTLDLDNMTQAEFDKQMAEIKERNPNIFQLISDFLDRKVTPEEVDEFLKMERAEQVEYIKNYQARV
>CP025838.1|AXJ87483.1|10490_10706_-|hypothetical-protein
MNELDISNTQAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTIKTPSEDLNPDYGRYIQLAGVNVWGGME
>CP025838.1|AXJ87482.1|10200_10494_-|hypothetical-protein
MSYTMNLYPDIEKIPDETYFTKEIFLATCLNNTIRIAVARGVLTSQLLDKETKEVVCKTLDTIIENQKAILQGVASGQITFVNKSKGEEGLDESIRE
>CP025838.1|AXJ87481.1|9878_10220_-|DNA-binding-protein
MSLSENDKRVLRLIKVGAENSITGSEISLTTKLTERTVRDIIKRLVVKHNIPIVGVRCGVFSGYFIPANKGELLDGAKAFYNQVQEESKRLAVLMNSDLESYKETLKEVGGYV
>CP025838.1|AXJ87480.1|9610_9886_-|hypothetical-protein
MFSLSRESEQDLAHGILEVVERYLEAREKVPPRLTKLINRVELKEELKISDNTLNKWESQGLRRYQPPDDGARIIFYLVDDIRRFMGVENG
>CP025838.1|AXJ89367.1|8610_9471_-|hypothetical-protein
MTIYEARGFQSNLVYPFDKMEPFQYIERFKPLVVPESADPEEYKRTQAPYCLSGKVMPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTTEDFIEAVSSALFGYSYILYPTIKHSIEKPRFRLVVKSNNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQGLPVTTGDPATYQKIVEHGLDYPVPKVEPRAKQGTTERYKPRVSGQRSMTMRIIDTLFNGFGDEGGRNVAVTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTFSSIARAEYRKRG
>CP025838.1|AXJ89366.1|7088_8558_-|DNA-primase
MEQEHPPRTMKELENRIFKAGEEWRAEHTETKVNETTGDVTEKVAMPQTFTVAKILSEIVTFTFISKSNIPDYSLLYIYDLDEGIYTASNDLFNLLCKTFDVRIKPREWPQIKLMVRTLAKIRKPLESANLVPVKNGIIDLRTKELLPFSPKYVITSKISTAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINPNHTRNKFAIFYGDGNNGKGTFQRFLINLIGESNISALKPAQFGEKHNLETLVGKVCNIGDEAPNEYLKNPSDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVPFNADFNGEKEKPWIKNEFLANKEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEDNDYLLSWVKHEYMEKGWHELDVVPVFIVTRSLKHYAEDMGIPKPNVYGAGKETIKHLQQLTPNRYSLRKKRVPSEDFEKLEAWDVDKIKMRTPQHSITKQE
>CP025838.1|AXJ87479.1|4834_5044_+|hypothetical-protein
MYNDGVKLIEVRGEGDIATFSAFARSSTHITLPFSRHIYCHYLSKISPFLTLGKPLYLVVTLGLLNTQP
>CP025838.1|AXJ87478.1|4707_4923_-|hypothetical-protein
MCVELRANAEKVAISPSPRTSMSFTPSLYIFSHGEAFEARANIEKTKKAKTLSVSANSSHKDYYIIEEAEA
>CP025838.1|AXJ87485.1|11808_12435_-|hypothetical-protein
MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESFGKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVKEFKKNLVKAFFEMREELSKFRMQRALEKPKRKTLHDSIKTWEAKPKHAHSTMNNLLLKAVTDMNAKQLVKSRGGYNGIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSV
>CP025838.1|AXJ87486.1|12524_12758_-|XRE-family-transcriptional-regulator
MEQWTLKACRVNAGYTLRQVAKKVNKNFQTVSKYEKDSTYIPFELLKELSAIYQVKLDNIFLGDSTKKIELNKRELQ
>CP025838.1|AXJ87487.1|12914_13871_+|XRE-family-transcriptional-regulator
MAKNSPQDLENREYFSKRLNLLMEQKGVRQIDLHNALDIPKSTITGYVKGKSLPTAGNLQKIADFLNVKKSFLDLRFIDTVSTSTLKELLDNNQREKVFEMFFNKIKEILSFKKDYMNMEYIRGKIAFDQGVLGRVLQSSIINPGIVEIFNGLDLSDISKNNEALLLSKQREAREYAYNNVLTMITNEYITRLINVIEREQALNTSYVHSEISNLINSLNNKIDSYGAVVFEVNEIIEKIGIQDRKILGYCLQRKISSVQNEINDLVHNNTNNSFCVTKNKIFTEKSDIIDTIEFDYYKGIQNRLNDLAEEIREHFSD
>CP025838.1|AXJ87488.1|14019_15024_+|DNA-binding-protein
MTDLTTSQIERQNILNNSLALQKAEEILKVPGFYFEDTFYFTNSQLATFFEVDIRTIERLVEAHKTELTENGYHTLRGEKLAKFKENAFATDTNVGSKVTQLSISSFRTLLNFAMLLTNSDIAKQVRNTLLDIVINVLTEKTGGHVKFINQRDKNYLSTALEEDNARKIFTNAIDKYVSGSNFKYGQLTNEIYKAIFKERASEYKKILKLNKNDNARATMYSEVLIVIASFEKGVAYEIEQKSKSSNQKLTNTDVIEIIQRLANHPMQEPHLMHAREKMASRDLSFRNAKHEKLAEYIRPISEEDFERFIGEQSKSLSEQIDEHRQVFERLRDK
>CP025838.1|AXJ87489.1|15023_15476_+|type-II-toxin-antitoxin-system-death-on-curing-family-toxin
MDKINYFSAEEAILLHDIEVIEKIGGLHGVKDKGRVFSVFEHLQNDDYYPDFETKLTVLVFNTVQFHMFNDGNKRSSIVFGIKFLTINHLDYLIPFFIETMENIVLWVAMGLIDFNFLKEIISSILYYEELTEKVKEKLVQIALAEENNK
>CP025838.1|AXJ87490.1|15571_16738_+|tyrosine-recombinase-XerS
MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELKAKALQAQIDFEKGGATVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKFKIDKYLLPAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYAVSLQAIPFNPARDVIVPRRKEKEGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLYKTLLATGLRIRECLALKWSDIDLKNGTLDVNKTLNIIKEITGPKTKSSIRVIDLDNKTVLMLRLYKARQSQIGKEMGLTYEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFHAFRHTHASILLNAGLPYKEIQIRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEKLKSS
>CP025838.1|AXJ87491.1|16857_17973_+|redox-regulated-ATPase-YchF
MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVHVVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKDKESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVVSEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYEDLVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV
>CP025838.1|AXJ87492.1|18043_18613_+|peptidyl-tRNA-hydrolase
MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIFQADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKIRLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGILQSVDKVDDSVNYYLQEKNFEKTMQRYNG
>CP025838.1|AXJ87493.1|18613_22138_+|transcription-repair-coupling-factor
MVTLLDLLSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASSLEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRVEALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENGYRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKTELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRKFLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDMQYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIERYKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHFVDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGIETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAKQKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEIKRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFKERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMIIDEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGRMSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGRVGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLGKSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQRHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRVERKDNKRKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEILEGLLIFGESLLEIKEFKEENSI
>CP025838.1|AXJ87494.1|22205_22472_+|RNA-binding-S4-domain-containing-protein
MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVNDQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV

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Crispr_ID: CP025838_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025838_2

113197-113292

Orphan

Consensus_repeat	Method
AATGTGTAAGATTTTTATATATAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP025838_2

>merge|CP025838|2|113197-113292|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAATTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGAAATGTGTAAAATTTTTATATATAA

>CP025838|2|2|113197-113292|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAA	TTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGA
AATGTGTAAAATTTTTATATATAA

Protein	Signature genes	Signature genes Name	Protein_function
CP025838.1\|AXJ87584.1\|123384_124257_+\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
CP025838.1\|AXJ87573.1\|112272_112866_-\|DUF1700-domain-containing-protein	unknown	unknown	gnl\|CDD\|227053
CP025838.1\|AXJ87568.1\|106349_107825_+\|DUF3502-domain-containing-protein	unknown	unknown	gnl\|CDD\|378792
CP025838.1\|AXJ87574.1\|112852_113179_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
CP025838.1\|AXJ87582.1\|121356_122220_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP025838.1\|AXJ87565.1\|104225_105155_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226666
CP025838.1\|AXJ87578.1\|118208_118841_-\|pyrophosphatase-PpaX	unknown	unknown	gnl\|CDD\|319798
CP025838.1\|AXJ87575.1\|113317_114484_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|225365
CP025838.1\|AXJ87576.1\|114541_115699_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133016
CP025838.1\|AXJ87579.1\|118862_119735_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|129801
CP025838.1\|AXJ87566.1\|105168_106092_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
CP025838.1\|AXJ87583.1\|122553_123141_+\|hypothetical-protein	unknown	unknown	unknown
CP025838.1\|AXJ87570.1\|109051_110065_+\|DUF4299-domain-containing-protein	unknown	unknown	gnl\|CDD\|339103
CP025838.1\|AXJ87567.1\|106165_106351_-\|hypothetical-protein	unknown	unknown	unknown
CP025838.1\|AXJ87580.1\|119743_120415_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	unknown	unknown	gnl\|CDD\|224674
CP025838.1\|AXJ87571.1\|110242_111307_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374284
CP025838.1\|AXJ87569.1\|108096_109083_+\|rhodanese-domain-containing-protein	unknown	unknown	gnl\|CDD\|234663
CP025838.1\|AXJ87577.1\|115740_117591_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
CP025838.1\|AXJ87581.1\|120654_121305_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|212030
CP025838.1\|AXJ87572.1\|111368_112280_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372574

Protein	Function_ID	Function_description	E-value
CP025838.1\|AXJ87584.1\|123384_124257_+\|XRE-family-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	2.58242e-11
CP025838.1\|AXJ87573.1\|112272_112866_-\|DUF1700-domain-containing-protein	gnl\|CDD\|227053	COG4709, COG4709, Predicted membrane protein [Function unknown].	7.70935e-64
CP025838.1\|AXJ87568.1\|106349_107825_+\|DUF3502-domain-containing-protein	gnl\|CDD\|378792	pfam12010, DUF3502, Domain of unknown function (DUF3502). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is about 140 amino acids in length. This domain is found associated with pfam01547.	4.04957e-44
CP025838.1\|AXJ87574.1\|112852_113179_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	3.12912e-19
CP025838.1\|AXJ87582.1\|121356_122220_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.15823e-10
CP025838.1\|AXJ87565.1\|104225_105155_+\|sugar-ABC-transporter-permease	gnl\|CDD\|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	3.01638e-143
CP025838.1\|AXJ87578.1\|118208_118841_-\|pyrophosphatase-PpaX	gnl\|CDD\|319798	cd04302, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to the Pseudomonas aeruginosa PA0065. 5'-nucleotidases dephosphorylate nucleoside 5'-monophosphates to nucleosides and inorganic phosphate. Purified Pseudomonas aeruginosa PA0065 displayed high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.0375e-97
CP025838.1\|AXJ87575.1\|113317_114484_-\|MFS-transporter	gnl\|CDD\|225365	COG2807, CynX, Cyanate permease [Inorganic ion transport and metabolism].	1.0335e-125
CP025838.1\|AXJ87576.1\|114541_115699_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133016	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.	3.88139e-109
CP025838.1\|AXJ87579.1\|118862_119735_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	1.44295e-105
CP025838.1\|AXJ87570.1\|109051_110065_+\|DUF4299-domain-containing-protein	gnl\|CDD\|339103	pfam14132, DUF4299, Domain of unknown function (DUF4299). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 275 and 313 amino acids in length. There are two conserved sequence motifs: RGF and DAY. There are two completely conserved residues (P and D) that may be functionally important.	1.9299e-120
CP025838.1\|AXJ87566.1\|105168_106092_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	5.04007e-69
CP025838.1\|AXJ87580.1\|119743_120415_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	gnl\|CDD\|224674	COG1760, SdaA, L-serine deaminase [Amino acid transport and metabolism].	1.1908e-89
CP025838.1\|AXJ87571.1\|110242_111307_-\|hypothetical-protein	gnl\|CDD\|374284	pfam16001, DUF4775, Domain of unknown function (DUF4775). This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 308 and 484 amino acids in length.	0.000306874
CP025838.1\|AXJ87569.1\|108096_109083_+\|rhodanese-domain-containing-protein	gnl\|CDD\|234663	PRK00142, PRK00142, rhodanese-related sulfurtransferase.	0
CP025838.1\|AXJ87577.1\|115740_117591_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
CP025838.1\|AXJ87581.1\|120654_121305_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	6.24547e-15
CP025838.1\|AXJ87572.1\|111368_112280_-\|hypothetical-protein	gnl\|CDD\|372574	pfam13349, DUF4097, Putative adhesin. This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.	1.41713e-39

>CP025838.1|AXJ87574.1|112852_113179_-|PadR-family-transcriptional-regulator
MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLYPILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGSIRHDKN
>CP025838.1|AXJ87573.1|112272_112866_-|DUF1700-domain-containing-protein
MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEELIASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILVTLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGASSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA
>CP025838.1|AXJ87572.1|111368_112280_-|hypothetical-protein
MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVYDSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDFITNQNDRTLSLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTIINASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAENIQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYKTEKTDVKDQLIARSDDNIDLISTPSRR
>CP025838.1|AXJ87571.1|110242_111307_-|hypothetical-protein
MKQEWFESNDFVKTTSKNKPEEQAQEVSDKAEETIADFDTPIGKNTQVEEEVSQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEESDLSKETEKVTIAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIKSPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLTLFSIVSILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIASFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIILLFFVAEVALIGDYLRILAFL
>CP025838.1|AXJ87570.1|109051_110065_+|DUF4299-domain-containing-protein
MKAWIKQLLYKIKQSSGAVFLCFVLKNLKFVSVSFRKIRYTVCKRFQRSPVMAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQPLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYTGTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLAQFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLVDKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILDKDFKALAQEE
>CP025838.1|AXJ87569.1|108096_109083_+|rhodanese-domain-containing-protein
MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV
>CP025838.1|AXJ87568.1|106349_107825_+|DUF3502-domain-containing-protein
MKNWKKYAFTSASVVALAAGLAACGNLTGNSKKAADSGDKPVIKMYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAFADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQNFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPVANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQDTWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEKSMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNWILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINTGTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK
>CP025838.1|AXJ87567.1|106165_106351_-|hypothetical-protein
MIKTPFFIFKLINNVMILYSMKIKEQTRKLAAGCSKHCFEVVDKTDEVSYIYLRQGDVDTV
>CP025838.1|AXJ87566.1|105168_106092_+|carbohydrate-ABC-transporter-permease
MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVFVIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNVFITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVPMLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTALGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMAMVVVATLPIAILYPFFQRYFVKGLTIGGVKE
>CP025838.1|AXJ87565.1|104225_105155_+|sugar-ABC-transporter-permease
MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYHMTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAIILSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFYADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIPQLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGMAAAAGLYQSVVGLILVILSNLLARRVDPNSALF
>CP025838.1|AXJ87575.1|113317_114484_-|MFS-transporter
MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSLGVLTSLPLLMFTLFSPFSSQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLMVGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIAAALASYLAVPITQASSWKGLILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFYTVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVSLAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGLSQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL
>CP025838.1|AXJ87576.1|114541_115699_+|glycosyltransferase-family-2-protein
MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIVISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIRLYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRPTIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNEQLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQFKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGFLIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML
>CP025838.1|AXJ87577.1|115740_117591_+|polysaccharide-biosynthesis-protein
MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILFYGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLSYSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGAGDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIERVIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGRQEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVYHELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFKNNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTYCAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAKDGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVDNQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE
>CP025838.1|AXJ87578.1|118208_118841_-|pyrophosphatase-PpaX
MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIRGFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPLYITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIIIGDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ
>CP025838.1|AXJ87579.1|118862_119735_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLMERNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASISGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE
>CP025838.1|AXJ87580.1|119743_120415_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta
MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPTEVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKDSNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDIPGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHNVNFFK
>CP025838.1|AXJ87581.1|120654_121305_+|LysM-peptidoglycan-binding-domain-containing-protein
MKSTTKKIKTTLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLSEIAETHNTTVEKLAENNHIDNIHMIYVGQELVIDGPVAPAATPAPTTYAAPAAQDETVSAPAAETTEVAEEAAPVASTPAAEETVATAETSAPAATVSGSEAEAKEWIAQKESGGSYTATNGQYIGRYQLTDSYLNGDYSAENQERVADAYVAGRYGSWSAAKNFWLNNGWY
>CP025838.1|AXJ87582.1|121356_122220_-|XRE-family-transcriptional-regulator
MRYDFGKVYKEIRESKGLTQEEVCGDVLSRTSLSKIESGKVTPKYENMEFLLRQINMSFEEFDYICHIYQPSQRTEIMQTYLNMNSIIGGSGLVHFFETCQNYLKTHHDLPIEEIRDMLEVVIHIRQHGTEQLSDQVKQTVKKLWEKIEKQDTWYESDLKILNTILFSFPIEHLHLITGKILQRLEVYKNYQHLYDLRMAILLNLSTIYLYHQDKNMCQQICYTLLEDAKNKKSYDMLAICYVRIGICRDDAKLIQKGLSLLELTDETSILAYLKKEVEIYYQPKER
>CP025838.1|AXJ87583.1|122553_123141_+|hypothetical-protein
MNYNVKYLLSGIFIIVFIGFLVWMRYFNQKKEEEHSDVSFEARLDSEVKTLYKQLGLGEEPHYFLAYRYLHPWFNLAILPPTVEIFLTKIALVMVTPDELLIRNLGNGMTFTSEHHRDLRQGLIRIPKSEMKEFEIRNWKRVFIFGDFLTIKTSQHSYYLQVRDDGLQKGSLSTKHFSDLKRQDFLGLLTDKRTF
>CP025838.1|AXJ87584.1|123384_124257_+|XRE-family-transcriptional-regulator
MHALLATRLKNKRKELGWSQKELAEGICQQTQISRMEQGKYMPGADLLYKLSEKMGLNMDYFFSGEISKEFLGLSAFKRLSKTLLENQDYASLKYAFEGERKQQTSLSFDEKIYLDWIDAILTYQCEHQLKLVISKIEDILSRISIDKVDYLYILNTLLIFLGYDEDKEKFEQLYDQVSVALSKIDTSVREQIELYIKIKYNYCYHLWKQEEMDKSRALLLEIIEFCNKYHSSFRLADLYCLLGNVTENLDISVAKDYYMKAKVLYLIENNEVMALKVEQYLMDKKSENV

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Crispr_ID: CP025838_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025838_3

1608900-1608983

Orphan

Consensus_repeat	Method
CTTTTTTGAAACGTTTCATTTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP025838_3

>merge|CP025838|3|1608900-1608983|CRISPRCasFinder
CTTTTTTGAAACGTTTCATTTTTTTCTAGAAAAGATAGCGCTTGGCGCTGTCTTTTTATTTCTTTTTTGAAACGTTTCATTTTT

>CP025838|3|3|1608900-1608983|CRISPRCasFinder
CTTTTTTGAAACGTTTCATTTTT	TTCTAGAAAAGATAGCGCTTGGCGCTGTCTTTTTATTT
CTTTTTTGAAACGTTTCATTTTT

Protein	Signature genes	Signature genes Name	Protein_function
CP025838.1\|AXJ88961.1\|1601113_1601320_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942
CP025838.1\|AXJ88965.1\|1602282_1603554_+\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
CP025838.1\|AXJ88977.1\|1615420_1616191_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
CP025838.1\|AXJ88978.1\|1616205_1617054_-\|formylglycine-generating-enzyme-family-protein	unknown	unknown	gnl\|CDD\|335469
CP025838.1\|AXJ88979.1\|1617050_1618526_-\|DUF4976-domain-containing-protein	unknown	unknown	gnl\|CDD\|237491
CP025838.1\|AXJ88960.1\|1600624_1601077_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|224514
CP025838.1\|AXJ88971.1\|1610402_1611884_-\|aspartate-aminotransferase	unknown	unknown	gnl\|CDD\|285470
CP025838.1\|AXJ88975.1\|1613321_1613930_+\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|224221
CP025838.1\|AXJ88973.1\|1612534_1613101_+\|alkaline-shock-response-membrane-anchor-protein-AmaP	unknown	unknown	gnl\|CDD\|380217
CP025838.1\|AXJ88968.1\|1607071_1607962_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
CP025838.1\|AXJ88970.1\|1609039_1610041_-\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
CP025838.1\|AXJ88972.1\|1612286_1612451_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
CP025838.1\|AXJ88967.1\|1605426_1607043_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270299
CP025838.1\|AXJ88966.1\|1604097_1605417_-\|beta-fructofuranosidase	unknown	unknown	gnl\|CDD\|224536
CP025838.1\|AXJ88962.1\|1601429_1601609_-\|hypothetical-protein	unknown	unknown	unknown
CP025838.1\|AXJ88976.1\|1613960_1614164_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
CP025838.1\|AXJ88974.1\|1613112_1613283_+\|DUF2273-domain-containing-protein	unknown	unknown	gnl\|CDD\|227834
CP025838.1\|AXJ88969.1\|1607972_1608890_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226666
CP025838.1\|AXJ88963.1\|1601773_1602013_-\|hypothetical-protein	unknown	unknown	unknown
CP025838.1\|AXJ88964.1\|1601935_1602142_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP025838.1\|AXJ88961.1\|1601113_1601320_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	8.85545e-09
CP025838.1\|AXJ88965.1\|1602282_1603554_+\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
CP025838.1\|AXJ88977.1\|1615420_1616191_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	4.67193e-17
CP025838.1\|AXJ88978.1\|1616205_1617054_-\|formylglycine-generating-enzyme-family-protein	gnl\|CDD\|335469	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1. This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.	2.99285e-66
CP025838.1\|AXJ88979.1\|1617050_1618526_-\|DUF4976-domain-containing-protein	gnl\|CDD\|237491	PRK13759, PRK13759, arylsulfatase; Provisional.	0
CP025838.1\|AXJ88972.1\|1612286_1612451_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	6.92661e-06
CP025838.1\|AXJ88975.1\|1613321_1613930_+\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|224221	COG1302, COG1302, Uncharacterized protein conserved in bacteria [Function unknown].	1.35166e-33
CP025838.1\|AXJ88960.1\|1600624_1601077_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	1.2282e-11
CP025838.1\|AXJ88973.1\|1612534_1613101_+\|alkaline-shock-response-membrane-anchor-protein-AmaP	gnl\|CDD\|380217	NF033218, anchor_AmaP, alkaline shock response membrane anchor protein AmaP. The founding member of this family, AmaP (Asp23 membrane anchoring protein), is related to Asp23 through part of its length, but includes a highly hydrophobic N-terminal region that should make it an integral membrane protein. Asp23 (alkaline shock protein of 23 kDa), described in PMID:7864904, is a cytosolic protein in Staphylococcus aureus, strongly induced by a pH shift from 7 to 10, and also recruited to the membrane. AmaP appears to be the partner protein with an integral membrane segment and the ability to anchor Asp23 to the membrane. This model was built to identify full-length homologs of AmaP, while excluding Asp23. Some but not all members of this family score above the cutoffs of Pfam model version PF03780.11, but full-length homologs of Asp23 score considerably higher. Asp23 family members previously were known as DUF322.	7.65552e-46
CP025838.1\|AXJ88968.1\|1607071_1607962_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	4.20755e-67
CP025838.1\|AXJ88970.1\|1609039_1610041_-\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.86275e-99
CP025838.1\|AXJ88967.1\|1605426_1607043_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270299	cd13581, PBP2_AlgQ_like_2, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold. This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.	0
CP025838.1\|AXJ88966.1\|1604097_1605417_-\|beta-fructofuranosidase	gnl\|CDD\|224536	COG1621, SacC, Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism].	6.65864e-177
CP025838.1\|AXJ88976.1\|1613960_1614164_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	1.20386e-07
CP025838.1\|AXJ88969.1\|1607972_1608890_-\|sugar-ABC-transporter-permease	gnl\|CDD\|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	1.73729e-138
CP025838.1\|AXJ88971.1\|1610402_1611884_-\|aspartate-aminotransferase	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	1.09342e-73
CP025838.1\|AXJ88974.1\|1613112_1613283_+\|DUF2273-domain-containing-protein	gnl\|CDD\|227834	COG5547, COG5547, Small integral membrane protein [Function unknown].	9.45975e-16

>CP025838.1|AXJ88969.1|1607972_1608890_-|sugar-ABC-transporter-permease
MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLIAFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAIMLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLTNPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPALKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTAVGLFNAVINVVLLVAVNQIVKRMNNGEGI
>CP025838.1|AXJ88968.1|1607071_1607962_-|carbohydrate-ABC-transporter-permease
MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDPKVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPLSKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILARAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIVMYPFFQKYFDKGIMAGSLKG
>CP025838.1|AXJ88967.1|1605426_1607043_-|ABC-transporter-substrate-binding-protein
MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQEKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDLPDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHIYSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNGNGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVKFIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAGPSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQQNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLDLIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWDDYKKELEKYGLSDYLAIKQKYYDQYQANKN
>CP025838.1|AXJ88966.1|1604097_1605417_-|beta-fructofuranosidase
MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNGFVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSGSAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKIEQNPVATGADLPDELIAADFRDPKLFEKDGRYYSVVATKHKDNVGCIVLLGSDNLVEWQFESIFLKGREHQGFMWECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDHGQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQFPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTSRRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID
>CP025838.1|AXJ88965.1|1602282_1603554_+|replication-associated-recombination-protein-A
MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMILYGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHRLDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQIALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITLDIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLARRLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYVAMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKIRNHHYFQAEDTGKYERALAQRKEAIDRLRKI
>CP025838.1|AXJ88964.1|1601935_1602142_+|hypothetical-protein
MTNLFCKNQNFLTWSIISIAYHLSFHYSSYNDIQQYYFSSQHFHFFRLNYPILSFKENQISHADTSPH
>CP025838.1|AXJ88963.1|1601773_1602013_-|hypothetical-protein
MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFREDTPKEILDLYENIKSKLDFAYQEVYSNNGLKKYEK
>CP025838.1|AXJ88962.1|1601429_1601609_-|hypothetical-protein
MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDYTDDELLDKEAVFTTH
>CP025838.1|AXJ88961.1|1601113_1601320_-|type-II-toxin-antitoxin-system-HicA-family-toxin
MVLSGGKSAIPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGELNKYTERGIGKQAGL
>CP025838.1|AXJ88960.1|1600624_1601077_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAMGSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSVDVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA
>CP025838.1|AXJ88970.1|1609039_1610041_-|LacI-family-transcriptional-regulator
MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQAIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCSINGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSDNDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDETVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKMAGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS
>CP025838.1|AXJ88971.1|1610402_1611884_-|aspartate-aminotransferase
MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESLFMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSPYDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE
>CP025838.1|AXJ88972.1|1612286_1612451_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVITVVSFFTGRK
>CP025838.1|AXJ88973.1|1612534_1613101_+|alkaline-shock-response-membrane-anchor-protein-AmaP
MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNSVVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFVRSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFGIERQVKLEVAVKNYQPKPQNKKTVSRVK
>CP025838.1|AXJ88974.1|1613112_1613283_+|DUF2273-domain-containing-protein
MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVAAGLYIEKNYIDK
>CP025838.1|AXJ88975.1|1613321_1613930_+|Asp23/Gls24-family-envelope-stress-response-protein
MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLENVSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSEIREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQFEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN
>CP025838.1|AXJ88976.1|1613960_1614164_+|CsbD-family-protein
MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVAEDAKDAVEGAVEGVKNMLSGDDK
>CP025838.1|AXJ88977.1|1615420_1616191_-|sulfite-exporter-TauE/SafE-family-protein
MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIAFYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVRLVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNVSLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGGVLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL
>CP025838.1|AXJ88978.1|1616205_1617054_-|formylglycine-generating-enzyme-family-protein
MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPVTNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGTPWWLQVPNACWKHPYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDTLLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRYTLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLGFRCLKE
>CP025838.1|AXJ88979.1|1617050_1618526_-|DUF4976-domain-containing-protein
MVQTKQPNIILIVVDQMRADVLSLNSKDKLVSTPTLDMMASVGYNFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTECIGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVDLIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPLNPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLITHIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIYDPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEFHGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQMKKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448629	Streptococcus satellite phage Javan742, complete genome	5187-5238	0	1.0
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448646	Streptococcus satellite phage Javan758, complete genome	5186-5237	0	1.0
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448432	Streptococcus satellite phage Javan327, complete genome	4489-4540	1	0.981
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448612	Streptococcus satellite phage Javan725, complete genome	3457-3508	3	0.942
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448495	Streptococcus satellite phage Javan434, complete genome	5542-5593	3	0.942
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448410	Streptococcus satellite phage Javan298, complete genome	3649-3700	3	0.942
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448614	Streptococcus satellite phage Javan727, complete genome	7482-7533	4	0.923
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448623	Streptococcus satellite phage Javan736, complete genome	6059-6110	4	0.923
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448630	Streptococcus satellite phage Javan743, complete genome	7931-7982	4	0.923
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448647	Streptococcus satellite phage Javan759, complete genome	10291-10342	5	0.904
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448643	Streptococcus satellite phage Javan755, complete genome	6646-6697	5	0.904
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448649	Streptococcus satellite phage Javan760, complete genome	4331-4382	5	0.904
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448616	Streptococcus satellite phage Javan729, complete genome	8547-8598	5	0.904
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448627	Streptococcus satellite phage Javan740, complete genome	7031-7082	5	0.904
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	KT337367	Streptococcus phage phiARI0826b, partial genome	32391-32442	7	0.865
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	KT337369	Streptococcus phage phiARI0831b, partial genome	29445-29496	7	0.865
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	FR671407	Streptococcus phage 34117	36073-36124	7	0.865
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	NC_024361	Streptococcus phage DCC1738, complete sequence	36829-36880	7	0.865
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	NC_024357	Streptococcus phage K13, complete sequence	37797-37848	7	0.865
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448640	Streptococcus satellite phage Javan752, complete genome	3884-3935	7	0.865
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448634	Streptococcus satellite phage Javan747, complete genome	2570-2621	7	0.865
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448986	Streptococcus phage Javan570, complete genome	1517-1568	8	0.846
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448455	Streptococcus satellite phage Javan364, complete genome	3323-3374	8	0.846
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448445	Streptococcus satellite phage Javan344, complete genome	5150-5201	9	0.827
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448555	Streptococcus satellite phage Javan592, complete genome	3565-3616	11	0.788
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448547	Streptococcus satellite phage Javan572, complete genome	3566-3617	11	0.788
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448535	Streptococcus satellite phage Javan550, complete genome	3566-3617	11	0.788
CP025838_1	1.1\|11501\|52\|CP025838\|CRISPRCasFinder	11501-11552	52	MK448544	Streptococcus satellite phage Javan564, complete genome	2943-2994	11	0.788

1. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448629 (Streptococcus satellite phage Javan742, complete genome) position: , mismatch: 0, identity: 1.0

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	Protospacer
****************************************************

2. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448646 (Streptococcus satellite phage Javan758, complete genome) position: , mismatch: 0, identity: 1.0

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	Protospacer
****************************************************

3. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448432 (Streptococcus satellite phage Javan327, complete genome) position: , mismatch: 1, identity: 0.981

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
cctacagcctcacgctctcggtcgccaaacttctgagcgtggggctttttga	Protospacer
************.***************************************

4. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448612 (Streptococcus satellite phage Javan725, complete genome) position: , mismatch: 3, identity: 0.942

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
tctacagcctcatgctctcggtcgccaaatttctgaacgtggggctttttga	Protospacer
.****************************.******.***************

5. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448495 (Streptococcus satellite phage Javan434, complete genome) position: , mismatch: 3, identity: 0.942

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
cctacagcctcatgctctcggtcgccaaatttctgagcatggggctttttaa	Protospacer
*****************************.********.***********.*

6. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448410 (Streptococcus satellite phage Javan298, complete genome) position: , mismatch: 3, identity: 0.942

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
cctacagcctcatgctctcggtcgccaaatttctgagcatggggctttttaa	Protospacer
*****************************.********.***********.*

7. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448614 (Streptococcus satellite phage Javan727, complete genome) position: , mismatch: 4, identity: 0.923

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-tcacatgcctcacgctctcggtcgccaaacttctgagcgtggggctttttga	Protospacer
 ..*** ******.***************************************

8. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448623 (Streptococcus satellite phage Javan736, complete genome) position: , mismatch: 4, identity: 0.923

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-tcacatgcctcatgctctcggtcgccaaacttctgagcgtgggtctttttga	Protospacer
 ..*** ************************************* ********

9. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448630 (Streptococcus satellite phage Javan743, complete genome) position: , mismatch: 4, identity: 0.923

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-tcacatgcctcacgctctcggtcgccaaacttctgagcgtggggctttttga	Protospacer
 ..*** ******.***************************************

10. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448647 (Streptococcus satellite phage Javan759, complete genome) position: , mismatch: 5, identity: 0.904

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-tcacatgcctcatgctctcggtcgccaaacttctgagcgtggggcttttttg	Protospacer
 ..*** ******************************************** .

11. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448643 (Streptococcus satellite phage Javan755, complete genome) position: , mismatch: 5, identity: 0.904

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-tcacatgcctcatgctctcggtcgccaaatttctgagcgtgggtctttttga	Protospacer
 ..*** ***********************.************* ********

12. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448649 (Streptococcus satellite phage Javan760, complete genome) position: , mismatch: 5, identity: 0.904

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-ccacatgcctcacgctctcggtcgccaaacttctgagcgtggggctttttac	Protospacer
 *.*** ******.*************************************.

13. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448616 (Streptococcus satellite phage Javan729, complete genome) position: , mismatch: 5, identity: 0.904

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-tcacatgcctcatgctctcggtcgccaaatttctgagcgtgggtctttttga	Protospacer
 ..*** ***********************.************* ********

14. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448627 (Streptococcus satellite phage Javan740, complete genome) position: , mismatch: 5, identity: 0.904

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-tcacatgcctcacgctctcggtcgccaaacttctgagcgtgggtctttttga	Protospacer
 ..*** ******.****************************** ********

15. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to KT337367 (Streptococcus phage phiARI0826b, partial genome) position: , mismatch: 7, identity: 0.865

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
gtactagcctcatgctctcggtcgccaaacttctgagcgtggggcttttttt	Protospacer
 .  .*********************************************

16. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to KT337369 (Streptococcus phage phiARI0831b, partial genome) position: , mismatch: 7, identity: 0.865

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
gtactagcctcatgctctcggtcgccaaacttctgagcgtggggcttttttt	Protospacer
 .  .*********************************************

17. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to FR671407 (Streptococcus phage 34117) position: , mismatch: 7, identity: 0.865

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
ctcctagcctcacgctctcggtcgccaaacttctgagcgtggggcttttttg	Protospacer
*.. .*******.************************************* .

18. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to NC_024361 (Streptococcus phage DCC1738, complete sequence) position: , mismatch: 7, identity: 0.865

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
ctcctagcctcacgctctcggtcgccaaacttctgagcgtggggcttttttg	Protospacer
*.. .*******.************************************* .

19. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to NC_024357 (Streptococcus phage K13, complete sequence) position: , mismatch: 7, identity: 0.865

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
ctcctagcctcacgctctcggtcgccaaacttctgagcgtggggcttttttg	Protospacer
*.. .*******.************************************* .

20. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448640 (Streptococcus satellite phage Javan752, complete genome) position: , mismatch: 7, identity: 0.865

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
tcgcatgcctcatgctctcggtcgccaaatttctgagcgtgggtctttttga	Protospacer
.*    ***********************.************* ********

21. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448634 (Streptococcus satellite phage Javan747, complete genome) position: , mismatch: 7, identity: 0.865

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
tcgcatgcctcatgctctcggtcgccaaatttctgagcgtgggtctttttga	Protospacer
.*    ***********************.************* ********

22. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448986 (Streptococcus phage Javan570, complete genome) position: , mismatch: 8, identity: 0.846

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
tagcttgcctcacgctctcggtcgccaaacttctgagcgtggggctttttta	Protospacer
.   . ******.************************************* *

23. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448455 (Streptococcus satellite phage Javan364, complete genome) position: , mismatch: 8, identity: 0.846

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
tgaagttcctcacgctctcggtcgccaaatttctgagcgtggggctttttga	Protospacer
.  *   *****.****************.**********************

24. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448445 (Streptococcus satellite phage Javan344, complete genome) position: , mismatch: 9, identity: 0.827

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
aggatatcctcacactctcggtcgccaaacttctgagcgtggggcttttttg	Protospacer
   *.* *****..************************************ .

25. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448555 (Streptococcus satellite phage Javan592, complete genome) position: , mismatch: 11, identity: 0.788

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
gtaattgcctcatgctctcggtcgcctaatttctgagcgtggggctttggtt	Protospacer
 . *. ******************** **.******************

26. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448547 (Streptococcus satellite phage Javan572, complete genome) position: , mismatch: 11, identity: 0.788

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
gtaattgcctcatgctctcggtcgcctaatttctgagcgtggggctttggtt	Protospacer
 . *. ******************** **.******************

27. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448535 (Streptococcus satellite phage Javan550, complete genome) position: , mismatch: 11, identity: 0.788

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
gtaattgcctcatgctctcggtcgcctaatttctgagcgtggggctttggtt	Protospacer
 . *. ******************** **.******************

28. spacer 1.1|11501|52|CP025838|CRISPRCasFinder matches to MK448544 (Streptococcus satellite phage Javan564, complete genome) position: , mismatch: 11, identity: 0.788

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
gtaattgcctcatgctctcggtcgcctaatttctgagcgtggggctttggtt	Protospacer
 . *. ******************** **.******************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

7088 : 16738

Streptococcus_phage(55.56%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ89366.1\|7088_8558_-	DNA primase	Q9AZI5	Lactococcus_phage	6.8e-64	34.5
AXJ89367.1\|8610_9471_-	hypothetical protein	A0A1X9I6L2	Streptococcus_phage	6.5e-123	74.5
AXJ87480.1\|9610_9886_-	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	5.6e-20	56.8
AXJ87481.1\|9878_10220_-	DNA-binding protein	NA	NA	NA	NA
AXJ87482.1\|10200_10494_-	hypothetical protein	NA	NA	NA	NA
AXJ87483.1\|10490_10706_-	hypothetical protein	NA	NA	NA	NA
AXJ87484.1\|10707_10908_-	hypothetical protein	NA	NA	NA	NA
AXJ89368.1\|10904_11300_-	hypothetical protein	A7J274	Streptococcus_phage	1.3e-06	34.8
AXJ87485.1\|11808_12435_-	hypothetical protein	R9QNB1	Lactococcus_phage	6.1e-30	40.8
AXJ87486.1\|12524_12758_-	XRE family transcriptional regulator	Q38329	Lactococcus_phage	6.4e-09	50.0
AXJ87487.1\|12914_13871_+	XRE family transcriptional regulator	A0A060QNS7	Streptococcus_phage	5.5e-14	41.0
AXJ87488.1\|14019_15024_+	DNA-binding protein	Q331X4	Clostridium_botulinum_C_phage	3.4e-14	28.9
AXJ87489.1\|15023_15476_+	type II toxin-antitoxin system death-on-curing family toxin	NA	NA	NA	NA
AXJ87490.1\|15571_16738_+	tyrosine recombinase XerS	A0A1X9I5Y5	Streptococcus_phage	5.9e-103	51.5

DBSCAN-SWA_2

58910 : 70366

Cyanophage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ87524.1\|58910_61064_+	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	4.2e-46	28.2
AXJ87525.1\|61076_62426_+	HlyD family secretion protein	NA	NA	NA	NA
AXJ87526.1\|62553_63303_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D7SE76	Cyanophage	3.7e-42	40.1
AXJ89372.1\|63304_63448_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	NA	NA	NA	NA
AXJ87527.1\|63504_67230_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	3.6e-37	25.6
AXJ87528.1\|67322_68765_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.7e-55	35.1
AXJ87529.1\|68801_69824_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	1.2e-64	43.9
AXJ87530.1\|69820_70366_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.4e-24	35.0

DBSCAN-SWA_3

789981 : 851755

Streptococcus_phage(45.83%)

tRNA,protease,integrase,transposase

attL 812113:812162|attR 846580:846629

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ88196.1\|789981_791196_+\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
AXJ88197.1\|791330_792155_+	esterase	NA	NA	NA	NA
AXJ88198.1\|792167_793334_+	ATP-grasp domain-containing protein	NA	NA	NA	NA
AXJ88199.1\|793841_795335_+	SAM-dependent DNA methyltransferase	J7I0U9	Acinetobacter_phage	4.0e-35	31.7
AXJ88200.1\|795347_796271_+	restriction endonuclease subunit S	NA	NA	NA	NA
AXJ88201.1\|796362_796599_+	AbrB family transcriptional regulator	NA	NA	NA	NA
AXJ88202.1\|796595_797009_+	type II toxin-antitoxin system death-on-curing family toxin	A0A0N9SKD8	Staphylococcus_phage	3.1e-14	38.5
AXJ88203.1\|797126_798092_+\|integrase	integrase	A0A2H4JAA2	uncultured_Caudovirales_phage	1.4e-33	29.6
AXJ88204.1\|798125_799169_+	restriction endonuclease subunit S	NA	NA	NA	NA
AXJ88205.1\|799198_802549_+	DUF4145 domain-containing protein	A0A2I7RGD1	Vibrio_phage	9.6e-13	25.2
AXJ88206.1\|803054_803525_-	arginine repressor	NA	NA	NA	NA
AXJ88207.1\|803541_805815_-	Xaa-Pro dipeptidyl-peptidase	NA	NA	NA	NA
AXJ88208.1\|806133_809262_+	DNA polymerase III subunit alpha	A0A291AWR1	Streptomyces_phage	3.1e-114	32.8
AXJ88209.1\|809344_810352_+	ATP-dependent 6-phosphofructokinase	NA	NA	NA	NA
AXJ88210.1\|810410_811916_+	pyruvate kinase	NA	NA	NA	NA
812113:812162	attL	NA	NA	NA	NA
AXJ88211.1\|812225_812474_-\|integrase	integrase	A0A1S5S8R9	Streptococcus_phage	1.7e-12	52.1
AXJ88212.1\|813021_813276_-	phage repressor protein	B3GVX0	Streptococcus_phage	3.3e-19	61.2
AXJ88213.1\|813711_814584_+	DUF4300 domain-containing protein	NA	NA	NA	NA
AXJ88214.1\|815216_815528_+	hypothetical protein	NA	NA	NA	NA
AXJ88215.1\|815531_816248_+	alpha/beta hydrolase	NA	NA	NA	NA
AXJ88216.1\|816369_817626_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	4.5e-234	97.1
AXJ88217.1\|817798_818614_-	TIGR03943 family protein	NA	NA	NA	NA
AXJ88218.1\|818610_819516_-	permease	NA	NA	NA	NA
AXJ88219.1\|819516_819648_-	hypothetical protein	NA	NA	NA	NA
AXJ88220.1\|819972_822102_+	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
AXJ88221.1\|822088_822538_+	SprT family protein	NA	NA	NA	NA
AXJ88222.1\|822566_822869_+	PspC domain-containing protein	NA	NA	NA	NA
AXJ88223.1\|823222_823414_-	hypothetical protein	NA	NA	NA	NA
AXJ88224.1\|823841_824600_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.7e-27	36.3
AXJ88225.1\|824601_826590_+	ABC transporter permease	NA	NA	NA	NA
AXJ88226.1\|827300_828296_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	1.4e-33	33.6
AXJ88227.1\|828528_828711_-	hypothetical protein	NA	NA	NA	NA
AXJ88228.1\|829002_830478_+	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
AXJ88229.1\|831413_832274_+	polyamine aminopropyltransferase	A0A1C9C533	Heterosigma_akashiwo_virus	1.0e-11	30.0
AXJ88230.1\|833528_834656_+	carboxynorspermidine decarboxylase	NA	NA	NA	NA
AXJ88231.1\|834652_835738_+	agmatine deiminase	M1HES8	Acanthocystis_turfacea_Chlorella_virus	1.6e-89	47.5
AXJ88232.1\|835747_836623_+	N-carbamoylputrescine amidase	M1H5W0	Paramecium_bursaria_Chlorella_virus	1.9e-77	50.0
AXJ88233.1\|836803_837613_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
AXJ88234.1\|837884_838106_+	hypothetical protein	NA	NA	NA	NA
AXJ88235.1\|838159_838831_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AXJ88236.1\|839072_839981_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	3.1e-06	27.7
AXJ88237.1\|839977_840439_+	signal peptidase II	NA	NA	NA	NA
AXJ88238.1\|840428_841316_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	3.8e-09	27.5
AXJ88239.1\|841318_843202_+	MBL fold metallo-hydrolase	I2E8W4	Clostridium_phage	1.7e-14	25.2
AXJ88240.1\|843281_844412_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-114	58.4
AXJ88241.1\|844421_845684_+	gamma-glutamyl-phosphate reductase	A0A1X9I5D4	Streptococcus_phage	5.0e-140	64.8
AXJ88242.1\|845687_846485_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.1e-60	50.9
AXJ88243.1\|846706_847345_+	thymidylate kinase	M1PSC7	Streptococcus_phage	1.7e-75	68.1
846580:846629	attR	NA	NA	NA	NA
AXJ88244.1\|847341_848232_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	1.4e-72	51.4
AXJ88245.1\|848271_848589_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.9e-28	60.0
AXJ88246.1\|848591_849461_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.8e-115	75.7
AXJ88247.1\|849687_850206_+	cytoplasmic protein	NA	NA	NA	NA
AXJ88248.1\|850314_850962_+	hypothetical protein	A0A2P0VK56	Streptococcus_phage	7.0e-13	33.7
AXJ88249.1\|850950_851755_-\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

1065367 : 1126351

Bacillus_virus(14.29%)

bacteriocin,protease,transposase,holin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ88437.1\|1065367_1065670_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
AXJ88438.1\|1065910_1066789_-\|tRNA	tRNA pseudouridine(55) synthase TruB	A0A1V0SF38	Hokovirus	4.3e-05	24.3
AXJ88439.1\|1066798_1068073_-	DUF2130 domain-containing protein	NA	NA	NA	NA
AXJ88440.1\|1069576_1070374_-	formate-nitrite transporter	NA	NA	NA	NA
AXJ88441.1\|1070617_1071361_-	sortase	NA	NA	NA	NA
AXJ88442.1\|1071360_1073829_-	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	4.6e-105	35.5
AXJ88443.1\|1074022_1075009_+	L-lactate dehydrogenase	NA	NA	NA	NA
AXJ88444.1\|1075345_1076041_-	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	5.4e-19	44.0
AXJ88445.1\|1076087_1076351_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A1S5S8E8	Streptococcus_phage	9.4e-17	50.0
AXJ88446.1\|1076343_1076646_-	antitoxin	NA	NA	NA	NA
AXJ88447.1\|1076779_1078036_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	6.6e-233	96.7
AXJ88448.1\|1078099_1078909_-	MBL fold metallo-hydrolase	A0A0C5AFC1	Paenibacillus_phage	1.8e-34	39.0
AXJ88449.1\|1078910_1080260_-	cell wall metabolism sensor histidine kinase VicK	W8CYF6	Bacillus_phage	5.2e-34	34.0
AXJ88450.1\|1080252_1080957_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	2.8e-39	39.8
AXJ88451.1\|1081012_1082188_-	A/G-specific adenine glycosylase	G3CB03	Aeropyrum_pernix_spindle-shaped_virus	8.8e-22	29.8
AXJ88452.1\|1082515_1084186_-	formate--tetrahydrofolate ligase	NA	NA	NA	NA
AXJ89404.1\|1084415_1085105_+	phosphopantothenate--cysteine ligase	Q9HH70	Methanothermobacter_phage	6.5e-17	31.6
AXJ88453.1\|1085116_1085668_+	phosphopantothenoylcysteine decarboxylase	A0A1V0S7W6	Shearwaterpox_virus	3.1e-25	36.1
AXJ88454.1\|1085651_1086215_+	ECF transporter S component	NA	NA	NA	NA
AXJ88455.1\|1086496_1087024_+	hypothetical protein	NA	NA	NA	NA
AXJ88456.1\|1087035_1087551_+	transcription repressor NadR	NA	NA	NA	NA
AXJ88457.1\|1087547_1088015_-	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
AXJ88458.1\|1088087_1088576_-	N-acetyltransferase	NA	NA	NA	NA
AXJ88459.1\|1088541_1089105_-	N-acetyltransferase	NA	NA	NA	NA
AXJ88460.1\|1089114_1091103_-	excinuclease ABC subunit B	NA	NA	NA	NA
AXJ88461.1\|1091179_1092133_-\|protease	CPBP family intramembrane metalloprotease domain-containing protein	NA	NA	NA	NA
AXJ88462.1\|1092305_1094471_+	amino acid ABC transporter permease	NA	NA	NA	NA
AXJ88463.1\|1094470_1095211_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.3e-33	40.6
AXJ88464.1\|1095359_1096847_+	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	2.2e-70	32.9
AXJ88465.1\|1096890_1098111_-	signal recognition particle-docking protein FtsY	NA	NA	NA	NA
AXJ88466.1\|1098114_1098933_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
AXJ88467.1\|1098932_1099727_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
AXJ88468.1\|1099723_1103263_-	chromosome segregation protein SMC	NA	NA	NA	NA
AXJ88469.1\|1103253_1103952_-	ribonuclease 3	A0A2K9L5P0	Tupanvirus	2.2e-28	35.2
AXJ88470.1\|1104269_1105256_-	guanosine monophosphate reductase	G3MBI2	Bacillus_virus	1.4e-137	72.2
AXJ88471.1\|1105430_1106774_-	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
AXJ88472.1\|1106733_1108668_-	endonuclease	K4I1H4	Acidithiobacillus_phage	1.2e-15	33.1
AXJ88473.1\|1109718_1110078_-	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
AXJ88474.1\|1110081_1110351_-	DUF1294 domain-containing protein	NA	NA	NA	NA
AXJ88475.1\|1111395_1112490_-	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	9.1e-05	37.5
AXJ88476.1\|1112508_1113165_-	MmcQ family protein	NA	NA	NA	NA
AXJ88477.1\|1113208_1113841_-	copper homeostasis protein CutC	NA	NA	NA	NA
AXJ88478.1\|1113933_1114293_-	DUF454 domain-containing protein	NA	NA	NA	NA
AXJ88479.1\|1114398_1116486_-	type I DNA topoisomerase	A0A1V0SCS0	Indivirus	2.5e-104	37.3
AXJ88480.1\|1116653_1117697_-	TIGR00341 family protein	NA	NA	NA	NA
AXJ88481.1\|1118581_1119430_-	DNA-protecting protein DprA	S6BFL3	Thermus_phage	4.2e-34	39.5
AXJ88482.1\|1119525_1120215_-\|holin	CTP--phosphocholine cytidylyltransferase	G3MA50	Bacillus_virus	9.5e-08	48.6
AXJ88483.1\|1120226_1121117_-	EamA/RhaT family transporter	NA	NA	NA	NA
AXJ88484.1\|1121094_1121964_-\|holin	choline kinase	NA	NA	NA	NA
AXJ88485.1\|1121980_1123003_-	ribitol-5-phosphate dehydrogenase	NA	NA	NA	NA
AXJ88486.1\|1123007_1123715_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
AXJ88487.1\|1124050_1125538_+	virulence factor MviN	NA	NA	NA	NA
AXJ88488.1\|1125547_1126351_+\|holin	phosphorylcholine transferase LicD	A0A1V0SD50	Indivirus	4.0e-10	27.1

DBSCAN-SWA_5

1159658 : 1188469

Streptococcus_phage(88.0%)

protease,integrase,transposase

attL 1152858:1152872|attR 1190461:1190475

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1152858:1152872	attL	NA	NA	NA	NA
AXJ88520.1\|1159658_1159973_+	DUF961 domain-containing protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
AXJ88521.1\|1159988_1160375_+	DUF961 domain-containing protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
AXJ88522.1\|1160403_1161789_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
AXJ88523.1\|1161965_1163384_+	helix-turn-helix domain-containing protein	A0A1S5SEX3	Streptococcus_phage	1.5e-233	100.0
AXJ88524.1\|1163432_1163516_+	23S rRNA methyltransferase attenuator leader peptide ErmL	NA	NA	NA	NA
AXJ88525.1\|1163640_1164378_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	3.1e-134	99.2
AXJ88526.1\|1164382_1164514_+	hypothetical protein	E4ZFP9	Streptococcus_phage	7.9e-17	100.0
AXJ88527.1\|1164634_1165882_-\|transposase	ISL3 family transposase	Q6V7R1	Burkholderia_virus	3.9e-12	23.9
AXJ88528.1\|1166061_1166283_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
AXJ88529.1\|1166399_1166897_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
AXJ88530.1\|1166871_1167378_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
AXJ88531.1\|1167361_1169809_+	ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
AXJ88532.1\|1169811_1171989_+	hypothetical protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	99.9
AXJ88533.1\|1171985_1172987_+	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
AXJ88534.1\|1172983_1173871_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.4e-157	93.9
AXJ88535.1\|1174145_1174232_+	tetracycline resistance protein	NA	NA	NA	NA
AXJ88536.1\|1174247_1176167_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	97.3
AXJ88537.1\|1176267_1176453_+	conjugal transfer protein	D0R0F6	Streptococcus_phage	3.9e-17	67.9
AXJ88538.1\|1177065_1177149_+	23S rRNA methyltransferase attenuator leader peptide ErmL	NA	NA	NA	NA
AXJ88539.1\|1177273_1178011_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	1.4e-134	99.6
AXJ88540.1\|1178015_1178147_+	hypothetical protein	E4ZFP9	Streptococcus_phage	8.2e-14	90.7
AXJ88541.1\|1178365_1178920_+	resolvase	A0A0F7LA37	Escherichia_phage	2.3e-36	52.1
AXJ88542.1\|1178923_1181842_+\|transposase	DDE transposase	A0A1B0V7H9	Salmonella_phage	1.1e-169	36.1
AXJ89408.1\|1182341_1182413_+	hypothetical protein	NA	NA	NA	NA
AXJ88543.1\|1182641_1183064_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
AXJ88544.1\|1183060_1183291_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
AXJ88545.1\|1183516_1183768_-	hypothetical protein	NA	NA	NA	NA
AXJ88546.1\|1183751_1183955_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
AXJ88547.1\|1184036_1185254_+\|integrase	site-specific integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
AXJ88548.1\|1185468_1186056_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AXJ88549.1\|1186058_1186292_-	transcriptional regulator	NA	NA	NA	NA
AXJ88550.1\|1186304_1186685_-	hypothetical protein	NA	NA	NA	NA
AXJ88551.1\|1186677_1187127_-	hypothetical protein	NA	NA	NA	NA
AXJ88552.1\|1187110_1188469_-	DNA (cytosine-5-)-methyltransferase	A0A141E1L1	Streptococcus_phage	3.9e-130	56.3
1190461:1190475	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1283418 : 1289197

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ88647.1\|1283418_1284030_+	peptide deformylase	E3SLL2	Synechococcus_phage	4.9e-16	42.4
AXJ88648.1\|1284074_1284803_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
AXJ88649.1\|1284841_1285753_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	5.9e-90	51.5
AXJ88650.1\|1285818_1286055_-	DUF4059 domain-containing protein	NA	NA	NA	NA
AXJ88651.1\|1286120_1286864_-	L-cystine ABC transporter ATP-binding protein YecC	G9BWD6	Planktothrix_phage	4.7e-29	40.5
AXJ88652.1\|1286863_1287664_-	amino acid ABC transporter permease	NA	NA	NA	NA
AXJ88653.1\|1287821_1288178_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.2e-33	57.3
AXJ88654.1\|1288190_1288703_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.3e-46	55.6
AXJ88655.1\|1288702_1289197_-	N-acetyltransferase	M1PSC3	Streptococcus_phage	1.9e-42	52.1

DBSCAN-SWA_7

1352678 : 1425506

Streptococcus_phage(90.16%)

terminase,head,protease,holin,tRNA,tail,integrase

attL 1360173:1360205|attR 1433254:1433286

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ88715.1\|1352678_1353428_-\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
AXJ88716.1\|1353481_1353841_-	RNA-binding protein	NA	NA	NA	NA
AXJ88717.1\|1353842_1355243_-	Cof-type HAD-IIB family hydrolase	A0A1V0S9I2	Catovirus	2.0e-25	44.6
AXJ88718.1\|1355537_1355777_-	30S ribosomal protein S18	NA	NA	NA	NA
AXJ88719.1\|1355808_1356279_-	single-stranded DNA-binding protein	A0A286QQM5	Streptococcus_phage	9.2e-55	71.2
AXJ88720.1\|1356290_1356581_-	30S ribosomal protein S6	NA	NA	NA	NA
AXJ88721.1\|1358453_1359641_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
AXJ89413.1\|1359637_1360069_-	peptidase	NA	NA	NA	NA
AXJ88722.1\|1360161_1360356_+	hypothetical protein	NA	NA	NA	NA
1360173:1360205	attL	NA	NA	NA	NA
AXJ88723.1\|1360446_1360995_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
AXJ88724.1\|1361272_1362001_-	peroxide stress protein YaaA	A0A1X9I5I0	Streptococcus_phage	2.0e-40	39.0
AXJ88725.1\|1362079_1362259_-	DUF3953 domain-containing protein	NA	NA	NA	NA
AXJ88726.1\|1362410_1364006_-	hypothetical protein	NA	NA	NA	NA
AXJ88727.1\|1364017_1364428_-	peptide deformylase	A0A2I7R224	Vibrio_phage	1.3e-09	33.1
AXJ88728.1\|1364543_1365335_-	glutathione-dependent disulfide-bond oxidoreductase	NA	NA	NA	NA
AXJ88729.1\|1365347_1368044_-	cation-translocating P-type ATPase	M1I547	Acanthocystis_turfacea_Chlorella_virus	3.1e-70	28.5
AXJ88730.1\|1368347_1369532_+	cation-efflux pump	NA	NA	NA	NA
AXJ88731.1\|1369674_1371546_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	1.1e-55	31.1
AXJ88732.1\|1371542_1372742_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	6.9e-38	32.6
AXJ88733.1\|1372738_1373506_-	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
AXJ88734.1\|1373771_1374620_-	fatty acid-binding protein DegV	NA	NA	NA	NA
AXJ88735.1\|1374621_1375008_-	DUF1149 domain-containing protein	NA	NA	NA	NA
AXJ88736.1\|1375069_1376422_-	phosphoglucosamine mutase	NA	NA	NA	NA
AXJ88737.1\|1376445_1377225_-	YbbR-like domain-containing protein	NA	NA	NA	NA
AXJ88738.1\|1377211_1378069_-	TIGR00159 family protein	NA	NA	NA	NA
AXJ88739.1\|1377986_1378160_-	hypothetical protein	NA	NA	NA	NA
AXJ88740.1\|1378204_1379173_+	NAD(P)/FAD-dependent oxidoreductase	Q9JRK7	Streptococcus_phage	2.8e-66	100.0
AXJ88741.1\|1379299_1379527_+	hypothetical protein	NA	NA	NA	NA
AXJ88742.1\|1379425_1380382_-	autolysin	A0A1S5SBM2	Streptococcus_phage	1.5e-144	99.4
AXJ88743.1\|1380381_1380717_-\|holin	phage holin	A0A126GGL9	Streptococcus_phage	3.4e-51	99.1
AXJ88744.1\|1380720_1381020_-	hypothetical protein	A0A1S5SC89	Streptococcus_phage	1.4e-45	100.0
AXJ88745.1\|1381029_1381380_-	hypothetical protein	A0A060QMT7	Streptococcus_phage	4.7e-64	100.0
AXJ88746.1\|1381382_1381586_-	hypothetical protein	X2KU40	Streptococcus_phage	1.1e-25	100.0
AXJ88747.1\|1388127_1388478_-	hypothetical protein	A0A141E0R8	Streptococcus_phage	9.8e-62	99.1
AXJ88748.1\|1388486_1392080_-	hypothetical protein	A0A141E0R9	Streptococcus_phage	0.0e+00	98.6
AXJ88749.1\|1392066_1392417_-	hypothetical protein	A0A060QN56	Streptococcus_phage	2.1e-56	100.0
AXJ88750.1\|1392455_1392836_-	hypothetical protein	A0A1S5SF40	Streptococcus_phage	9.3e-66	100.0
AXJ88751.1\|1392840_1393254_-\|tail	phage tail protein	A0A1S5SF61	Streptococcus_phage	3.3e-72	99.3
AXJ88752.1\|1393256_1393625_-	hypothetical protein	A0A1S5SFB8	Streptococcus_phage	1.2e-65	100.0
AXJ88753.1\|1393621_1394137_-	hypothetical protein	A0A141E0I0	Streptococcus_phage	9.3e-93	100.0
AXJ89414.1\|1394111_1394414_-	hypothetical protein	X2KU30	Streptococcus_phage	2.0e-42	100.0
AXJ88754.1\|1394430_1394742_-\|head,tail	phage head-tail adapter protein	A0A1S5S8S7	Streptococcus_phage	7.2e-48	99.0
AXJ88755.1\|1394743_1394932_-	hypothetical protein	A0A141DZN7	Streptococcus_phage	1.4e-27	100.0
AXJ88756.1\|1394941_1395967_-	sugar-binding protein	A0A1S5S8Q2	Streptococcus_phage	7.3e-190	99.7
AXJ88757.1\|1395989_1396514_-	DUF4355 domain-containing protein	E8ZDV2	Streptococcus_phage	1.7e-73	98.9
AXJ88758.1\|1396995_1397409_-	HD domain-containing protein	A0A1S5SBR9	Streptococcus_phage	5.4e-67	100.0
AXJ88759.1\|1397405_1397615_-	hypothetical protein	A0A1S5SB88	Streptococcus_phage	3.3e-33	100.0
AXJ88760.1\|1397616_1399200_-\|head	phage head morphogenesis protein	A0A1S5SDJ1	Streptococcus_phage	5.1e-299	99.2
AXJ88761.1\|1400642_1401941_-\|terminase	PBSX family phage terminase large subunit	A0A141E1F1	Streptococcus_phage	7.2e-259	99.3
AXJ88762.1\|1401918_1402431_-\|terminase	terminase small subunit	A0A060QNR7	Streptococcus_phage	1.5e-87	99.4
AXJ88763.1\|1403700_1404123_-	DUF1492 domain-containing protein	A0A141E1Y4	Streptococcus_phage	6.3e-71	100.0
AXJ88764.1\|1404240_1404558_-	3-dehydroquinate synthase	A0A1S5SDY8	Streptococcus_phage	1.4e-51	98.1
AXJ88765.1\|1404619_1405147_-	DUF1642 domain-containing protein	A0A1S5SE80	Streptococcus_phage	2.4e-96	96.0
AXJ88766.1\|1405148_1405463_-	hypothetical protein	A0A1S5SDB3	Streptococcus_phage	1.5e-56	98.1
AXJ88767.1\|1405613_1405952_-	hypothetical protein	A0A1S5SDI1	Streptococcus_phage	5.6e-62	100.0
AXJ88768.1\|1406396_1407740_-	helicase	A0A1S5SAS5	Streptococcus_phage	7.7e-256	99.3
AXJ88769.1\|1407742_1408564_-	DNA primase	A0A1S5SDK7	Streptococcus_phage	6.5e-157	99.3
AXJ88770.1\|1408736_1409240_-	hypothetical protein	A0A126GGP3	Streptococcus_phage	2.9e-91	98.8
AXJ88771.1\|1409259_1410036_-	NTP-binding protein	A0A141DZQ7	Streptococcus_phage	8.7e-143	100.0
AXJ88772.1\|1410035_1410353_-	hypothetical protein	X2KPG0	Streptococcus_phage	2.0e-53	100.0
AXJ88773.1\|1410371_1411565_-	type III restriction endonuclease subunit R	X2KU10	Streptococcus_phage	5.3e-232	99.7
AXJ88774.1\|1411527_1412013_-	hypothetical protein	X2KUD4	Streptococcus_phage	1.4e-87	98.8
AXJ88775.1\|1412012_1412372_-	hypothetical protein	A0A1S5SB89	Streptococcus_phage	2.3e-58	99.2
AXJ88776.1\|1412371_1412854_-	hypothetical protein	A0A1S5S7W2	Streptococcus_phage	1.4e-79	100.0
AXJ88777.1\|1412846_1413569_-	HNH endonuclease	A0A141E0V1	Streptococcus_phage	3.3e-136	98.8
AXJ88778.1\|1413582_1413813_-	hypothetical protein	X2KU06	Streptococcus_phage	2.2e-33	100.0
AXJ88779.1\|1413813_1414155_-	hypothetical protein	A0A1S5S7X8	Streptococcus_phage	1.4e-57	100.0
AXJ88780.1\|1414166_1414358_-	hypothetical protein	A0A1S5SDN5	Streptococcus_phage	2.3e-28	100.0
AXJ88781.1\|1414354_1414549_-	hypothetical protein	X2KSX0	Streptococcus_phage	1.8e-09	100.0
AXJ88782.1\|1414545_1414818_-	hypothetical protein	A0A1S5SDW9	Streptococcus_phage	8.8e-42	100.0
AXJ88783.1\|1415158_1415350_+	hypothetical protein	X2KSW6	Streptococcus_phage	1.5e-27	98.4
AXJ88784.1\|1415303_1415510_-	hypothetical protein	A0A141E1R6	Streptococcus_phage	4.0e-31	100.0
AXJ88785.1\|1415532_1415724_-	DNA-binding protein	A0A141DZR9	Streptococcus_phage	3.0e-28	100.0
AXJ88786.1\|1415788_1416028_+	hypothetical protein	A0A141DZS0	Streptococcus_phage	4.7e-39	100.0
AXJ88787.1\|1416251_1416341_+	type I addiction module toxin, Fst family	NA	NA	NA	NA
AXJ88788.1\|1416563_1416656_+	type I addiction module toxin, Fst family	NA	NA	NA	NA
AXJ88789.1\|1417053_1417407_+	XRE family transcriptional regulator	A0A1S5SEQ8	Streptococcus_phage	7.1e-60	99.1
AXJ88790.1\|1417408_1418503_+	hypothetical protein	A0A1S5SFA1	Streptococcus_phage	3.5e-206	100.0
AXJ88791.1\|1418725_1419106_+	ImmA/IrrE family metallo-endopeptidase	A0A1S5SFH2	Streptococcus_phage	1.1e-66	99.2
AXJ88792.1\|1419247_1420375_+\|integrase	site-specific integrase	A0A1S5SEM0	Streptococcus_phage	4.5e-209	100.0
AXJ88793.1\|1420462_1421374_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.5e-154	99.7
AXJ88794.1\|1421370_1422348_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.2e-184	100.0
AXJ88795.1\|1422344_1423235_-	RNase adaptor protein RapZ	NA	NA	NA	NA
AXJ88796.1\|1423286_1423667_-	RidA family protein	NA	NA	NA	NA
AXJ88797.1\|1423677_1424265_-	GTP-binding protein	NA	NA	NA	NA
AXJ88798.1\|1424273_1425506_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-131	59.0
1433254:1433286	attR	NA	NA	NA	NA

DBSCAN-SWA_8

2034013 : 2042766

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ89346.1\|2034013_2034853_-	energy-coupling factor transporter ATPase	A0A2K9L3Z8	Tupanvirus	2.3e-16	29.8
AXJ89347.1\|2034837_2035665_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	2.1e-22	32.9
AXJ89348.1\|2035661_2036207_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
AXJ89349.1\|2036217_2037048_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AXJ89350.1\|2037080_2038364_-	insulinase family protein	A0A167R9K4	Powai_lake_megavirus	5.5e-17	30.7
AXJ89351.1\|2038360_2039611_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	8.6e-92	42.1
AXJ89352.1\|2039769_2040138_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	4.5e-17	56.0
AXJ89353.1\|2040140_2041238_+	DNA replication/repair protein RecF	NA	NA	NA	NA
AXJ89354.1\|2041287_2042766_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	4.9e-94	40.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP025838

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection