CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP022906	Staphylococcus aureus strain 546 chromosome, complete genome	12 crisprs	cas3,DEDDh,DinG,csa3,WYL	11	6	10	0
CP022907	Staphylococcus aureus strain 546 plasmid pPS00077.1A.1, complete sequence	0 crisprs	csa3	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP022906_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022906_1

46225-46335

Orphan

Consensus_repeat	Method
TATAAGGACTTAAATTATAAAACGTCCCT	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of CP022906_1

>merge|CP022906|1|46225-46335|CRISPRCasFinder
TATAAGGACTTAAATTATAAAACGTCCCTCTATAATAACTAACGAAAGAATTATAACACCTATTATATAGAGAATAAAGTTTATAAGTGACTTAAATTATAAAACGTCCCT

>CP022906|1|1|46225-46335|CRISPRCasFinder
TATAAGGACTTAAATTATAAAACGTCCCT	CTATAATAACTAACGAAAGAATTATAACACCTATTATATAGAGAATAAAGTTT
ATAAGTGACTTAAATTATAAAACGTCCCT

Protein	Signature genes	Signature genes Name	Protein_function
CP022906.1\|AXJ79537.1\|45460_46204_-\|Replication-initiation-protein	unknown	unknown	gnl\|CDD\|227814
CP022906.1\|AXJ79536.1\|44756_45431_-\|Integrase-core-domain-protein	unknown	unknown	gnl\|CDD\|225853
CP022906.1\|AXJ79539.1\|48420_48597_-\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ79542.1\|49626_50427_-\|Teichoic-acid-translocation-permease-protein-TagG	unknown	unknown	gnl\|CDD\|224596
CP022906.1\|AXJ79544.1\|52470_53145_+\|Integrase-core-domain-protein	unknown	unknown	gnl\|CDD\|225853
CP022906.1\|AXJ79528.1\|36738_36906_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225959
CP022906.1\|AXJ79540.1\|48593_48983_-\|Bacterial-mobilization-protein-(MobC)	unknown	unknown	gnl\|CDD\|368576
CP022906.1\|AXJ79532.1\|41162_42149_+\|Methicillin-resistance-mecR1-protein	unknown	unknown	gnl\|CDD\|226672
CP022906.1\|AXJ79535.1\|44030_44537_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226783
CP022906.1\|AXJ79543.1\|52267_52441_+\|FemAB-family-protein	unknown	unknown	gnl\|CDD\|225224
CP022906.1\|AXJ79531.1\|39056_41063_-\|Beta-lactam-inducible-penicillin-binding-protein	unknown	unknown	gnl\|CDD\|223839
CP022906.1\|AXJ79534.1\|42371_43895_-\|Transposase-DDE-domain-protein	unknown	unknown	gnl\|CDD\|372705
CP022906.1\|AXJ79541.1\|49251_49530_-\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ79538.1\|47423_48434_-\|Relaxase/mobilization-nuclease-domain-protein	unknown	unknown	gnl\|CDD\|367497
CP022906.1\|AXJ79533.1\|42120_42378_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378743
CP022906.1\|AXJ79547.1\|54711_55254_-\|TDP-fucosamine-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP022906.1\|AXJ79530.1\|38582_39011_+\|Bifunctional-protein-PaaZ	unknown	unknown	gnl\|CDD\|239538
CP022906.1\|AXJ79545.1\|53186_53549_-\|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
CP022906.1\|AXJ79546.1\|53824_54619_-\|Aminoglycoside-3'-phosphotransferase	unknown	unknown	gnl\|CDD\|270699
CP022906.1\|AXJ79529.1\|37742_38486_+\|Glycerophosphoryl-diester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176505

Protein	Function_ID	Function_description	E-value
CP022906.1\|AXJ79537.1\|45460_46204_-\|Replication-initiation-protein	gnl\|CDD\|227814	COG5527, COG5527, Protein involved in initiation of plasmid replication [DNA replication, recombination, and repair].	5.08439e-67
CP022906.1\|AXJ79536.1\|44756_45431_-\|Integrase-core-domain-protein	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.63523e-85
CP022906.1\|AXJ79542.1\|49626_50427_-\|Teichoic-acid-translocation-permease-protein-TagG	gnl\|CDD\|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	5.01664e-39
CP022906.1\|AXJ79544.1\|52470_53145_+\|Integrase-core-domain-protein	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.63523e-85
CP022906.1\|AXJ79528.1\|36738_36906_+\|hypothetical-protein	gnl\|CDD\|225959	COG3425, PksG, 3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism].	2.13677e-10
CP022906.1\|AXJ79540.1\|48593_48983_-\|Bacterial-mobilization-protein-(MobC)	gnl\|CDD\|368576	pfam05713, MobC, Bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region. The absence of MobC has several different effects on oriT DNA. Site- and strand-specific nicking by MobA protein is severely reduced, accounting for the lower frequency of mobilisation. The localized DNA strand separation required for this nicking is less affected, but becomes more sensitive to the level of active DNA gyrase in the cell. In addition, strand separation is not efficiently extended through the region containing the nick site. These effects suggest a model in which MobC acts as a molecular wedge for the relaxosome-induced melting of oriT DNA. The effect of MobC on strand separation may be partially complemented by the helical distortion induced by supercoiling. However, MobC extends the melted region through the nick site, thus providing the single-stranded substrate required for cleavage by MobA.	0.000876526
CP022906.1\|AXJ79532.1\|41162_42149_+\|Methicillin-resistance-mecR1-protein	gnl\|CDD\|226672	COG4219, MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component [Transcription / Signal transduction mechanisms].	1.47485e-138
CP022906.1\|AXJ79535.1\|44030_44537_-\|hypothetical-protein	gnl\|CDD\|226783	COG4333, COG4333, Uncharacterized protein conserved in bacteria [Function unknown].	1.03252e-77
CP022906.1\|AXJ79543.1\|52267_52441_+\|FemAB-family-protein	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	9.68026e-07
CP022906.1\|AXJ79531.1\|39056_41063_-\|Beta-lactam-inducible-penicillin-binding-protein	gnl\|CDD\|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	5.31602e-100
CP022906.1\|AXJ79534.1\|42371_43895_-\|Transposase-DDE-domain-protein	gnl\|CDD\|372705	pfam13751, DDE_Tnp_1_6, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	1.68136e-23
CP022906.1\|AXJ79546.1\|53824_54619_-\|Aminoglycoside-3'-phosphotransferase	gnl\|CDD\|270699	cd05150, APH, Aminoglycoside 3'-phosphotransferase. APH catalyzes the transfer of the gamma-phosphoryl group from ATP to aminoglycoside antibiotics such as kanamycin, streptomycin, neomycin, and gentamicin, among others. The aminoglycoside antibiotics target the 30S ribosome and promote miscoding, leading to the production of defective proteins which insert into the bacterial membrane, resulting in membrane damage and the ultimate demise of the bacterium. Phosphorylation of the aminoglycoside antibiotics results in their inactivation, leading to bacterial antibiotic resistance. The APH gene is found on transposons and plasmids and is thought to have originated as a self-defense mechanism used by microorganisms that produce the antibiotics. The APH subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	7.26961e-101
CP022906.1\|AXJ79538.1\|47423_48434_-\|Relaxase/mobilization-nuclease-domain-protein	gnl\|CDD\|367497	pfam03432, Relaxase, Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalyzing trans-esterification.	4.96368e-84
CP022906.1\|AXJ79533.1\|42120_42378_+\|hypothetical-protein	gnl\|CDD\|378743	pfam11867, DUF3387, Domain of unknown function (DUF3387). This domain is functionally uncharacterized. This domain is found in bacteria and archaea. This presumed domain is typically between 255 to 340 amino acids in length. This domain is found associated with pfam04851, pfam04313.	1.37468e-32
CP022906.1\|AXJ79547.1\|54711_55254_-\|TDP-fucosamine-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.19335e-21
CP022906.1\|AXJ79530.1\|38582_39011_+\|Bifunctional-protein-PaaZ	gnl\|CDD\|239538	cd03454, YdeM, YdeM is a Bacillus subtilis protein that belongs to a family of prokaryotic proteins of unkown function. YdeM has sequence similarity to the hot-dog fold of (R)-specific enoyl-CoA hydratase. Other enzymes with this fold include the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.	1.10823e-65
CP022906.1\|AXJ79545.1\|53186_53549_-\|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.64833e-26
CP022906.1\|AXJ79529.1\|37742_38486_+\|Glycerophosphoryl-diester-phosphodiesterase	gnl\|CDD\|176505	cd08562, GDPD_EcUgpQ_like, Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46), UgpQ, and similar proteins. GP-GDE plays an essential role in the metabolic pathway of E. coli. It catalyzes the degradation of glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols, which are major sources of carbon and phosphate. E. coli possesses two major G3P uptake systems: Glp and Ugp, which contain genes coding for two distinct GP-GDEs. UgpQ gene from the E. coli ugp operon codes for a cytosolic phosphodiesterase GlpQ, which is the prototype of this family. Various glycerophosphodiesters, such as glycerophosphocholine (GPC), glycerophosphoethanolanmine (GPE), glycerophosphoglycerol (GPG), glycerophosphoinositol (GPI), and glycerophosphoserine (GPS), can only be hydrolyzed by UgpQ during transport at the inner side of the cytoplasmic membrane to alcohols and G3P, which is a source of phosphate. In contrast to Ca2+-dependent periplasmic phosphodiesterase GlpQ, cytosolic phosphodiesterase UgpQ requires divalent cations, such as Mg2+, Co2+, or Mn2+, for its enzyme activity.	7.22645e-112

>CP022906.1|AXJ79537.1|45460_46204_-|Replication-initiation-protein
MSGETVVYRNEMNLVPLRRFTSTEVDLFFTLCNKLKEQDTRKVIIPFEELKYLSNYYTRSQERFINDLEHVYDKMLNLTYVERNGRSFEKFVLFTSYKVDLDEECLSISVNPDLKHILNSITADFTKFELKEMTHLKSTYAKNMFRLLKQYKHTGYVKINIADFRNRLDIPKTYQMNDITKRVLKPIINELSSIFNNLNINKIKAKKGRKIECLEFTFDAEKRIHSKRQPQMANIGKSRGSVAKLNL
>CP022906.1|AXJ79536.1|44756_45431_-|Integrase-core-domain-protein
MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRGRGVNVHHSTVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWLRKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLNNLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIMLAS
>CP022906.1|AXJ79535.1|44030_44537_-|hypothetical-protein
MNTIKSTIHTEAIFSDDEQHRYLLKKTWDEKKPACTVITMYPHLDGVLSLDLTTVLILNQLANTEQYGAVYLVNLFSNIRTPENLKHIKNPYDEHTDIHLMKAISESDTVILAYGAYAKRPVVIDRVEQVMEMLKPHKKKVKKLINPVTNEIMHPLNPKARQKWILKS
>CP022906.1|AXJ79534.1|42371_43895_-|Transposase-DDE-domain-protein
MMLKVILYAYTQSVFSGRKIEKMLNDSIRMMWLSQNQKPSYKTINQFRVNPKVDALLESLFIQFYSQCVKQNLIDDKAIFIDGTKIEANANRYTFVWKKSIQNHESKMNEDSKALYHELVTNKIIPEIKEDHDNELTKEEIDLIGSHLDKEIEDLNQHINNEKCTKTRKQIRLKRTKIKKYKKQINDYFERKYRYEFQKSILKDRNSYSKTDYDATFMRMKEDHMKNGQLKPGYNLQIATNSQFVLSYNVYQNPTDTRTMIPFLNSIQETYGHLPEYIVADAGYGSESNYKAIIDDFNRTPLITYGMFIKDKTKKYKSDIFNTQNWNYDEINDEFICPNNKRLGFKRYAYRHDKYGYKRDFKLYECDDCSECPLKNQCMNFNSKTNKKIMKNYNWEYFKSQINKKLSEPETKNIYSQRKIDVEPVFGFMKAILGFTRMSVRGLNKVKRELGFVLMALNIRKVVAQRAENNQKIYKKDNFYIISIEIVFFHLSKNFMSRTHYDLFFYY
>CP022906.1|AXJ79533.1|42120_42378_+|hypothetical-protein
MYVVYRASHETAKEALGDKELRAIAHELTKTVKDNMSVDWSKRDSAKAKMRVQVRRLLKKYGYPPDLQKMAVEQVVEQAELMASQ
>CP022906.1|AXJ79532.1|41162_42149_+|Methicillin-resistance-mecR1-protein
MLSSFLMLSIISSLLTICVIFLVRMLYIKYTQNIMSHKIWLLVLVSTLIPLIPFYKISNFTFSKDMMNRNVSDTTSSVSHMLDGQQSSVTKDLAINVNQFETSNITYMILLIWVFGSLLCLFYMIKAFRQIDVIKSSSLESSYLNERLKVCQSKMQFYKKHITISYSSNIDNPMVFGLVKSQIVLPTVVVETMNDKEIEYIILHELSHVKSHDLIFNQLYVVFKMIFWFNPALYISKTMMDNDCEKVCDRNVLKILNRHEHIRYGESILKCSILKSQHINNVAAQYLLGFNSNIKERVKYIALYDSMPKPNRNKRIVAYIVCSISSFT
>CP022906.1|AXJ79531.1|39056_41063_-|Beta-lactam-inducible-penicillin-binding-protein
MKKIKIVPLILIVVVVGFGIYFYASKDKEINNTIDAIEDKNFKQVYKDSSYISKSDNGEVEMTERPIKIYNSLGVKDINIQDRKIKKVSKNKKRVDAQYKIKTNYGNIDRNVQFNFVKEDGMWKLDWDHSVIIPGMQKDQSIHIENLKSERGKILDRNNVELANTGTAYEIGIVPKNVSKKDYKAIAKELSISEDYIKQQMDQNWVQDDTFVPLKTVKKMDEYLSDFAKKFHLTTNETESRNYPLEKATSHLLGYVGPINSEELKQKEYKGYKDDAVIGKKGLEKLYDKKLQHEDGYRVTIVDDNSNTIAHTLIEKKKKDGKDIQLTIDAKVQKSIYNNMKNDYGSGTAIHPQTGELLALVSTPSYDVYPFMYGMSNEEYNKLTEDKKEPLLNKFQITTSPGSTQKILTAMIGLNNKTLDDKTSYKIDGKGWQKDKSWGGYNVTRYEVVNGNIDLKQAIESSDNIFFARVALELGSKKFEKGMKKLGVGEDIPSDYPFYNAQISNKNLDNEILLADSGYGQGEILINPVQILSIYSALENNGNINAPHLLKDTKNKVWKKNIISKENINLLTDGMQQVVNKTHKEDIYRSYANLIGKSGTAELKMKQGETGRQIGWFISYDKDNPNMMMAINVKDVQDKGMASYNAKISGKVYDELYENGNKKYDIDE
>CP022906.1|AXJ79530.1|38582_39011_+|Bifunctional-protein-PaaZ
MKYDDFIVGETFKTKSLHITEEEIIQFATTFDPQYMHIDKEKAEQSRFKGIIASGMHTLSISFKLWVEEGKYGEEVVAGTQMNNVKFIKPVYPGNTLYVIAEITNKKSIKKENGLVTVSLSTYNENEEIVFKGEVTALINNS
>CP022906.1|AXJ79529.1|37742_38486_+|Glycerophosphoryl-diester-phosphodiesterase
MLTVYGHRGLPSKAPENTIASFKAASEVEGINWLELDVAITKDEQLIIIHDDYLERTTNMSGEITELNYDEIKDASAGSWFGEKFKDEHLPTFDDVVKIANEYNMNLNVELKGITGPNGLALSKSMVKQVEEQLTNLNQNQEVLISSFNVVLVKLAEEIMPQYNRAVIFHTTSFREDWRTLLDYCNAKIVNTEDAKLTKAKVKMVKEAGYELNVWTVNKPARANQLANWGVDGIFTDNADKMVHLSQ
>CP022906.1|AXJ79528.1|36738_36906_+|hypothetical-protein
MLESREQLSVEEYETFFNRFDNQEFDFERELTQDPYSKVYLYSIEDHIRTYKIEK
>CP022906.1|AXJ79538.1|47423_48434_-|Relaxase/mobilization-nuclease-domain-protein
MATTKLSATKSTSRAINYAEKRAVEKSGLNCDVDYAKSNFKAARELYGKTDGNQGHVIIQSFKPGEVTPEQCNQLGLALAEKLAPNHQVAVYTHADTDHVHNHIVINAINLETGKKFNNNKQALRDVRDFNDVVCREHGLSVPEKDTARLRYTQTEKAIADPNTQSTVQYSWKDEIREAIDQSQATNMDEFKDHLNQHGITIERVTPKSITYRHLAEDKKVRGRKLGEDYNKGGIEDGFERQIQRQQQTERASDTDVQPKRRTSSRDEETERDTGVTQSDWDKFAQDTNELERSRQAAESARLVDEKARRDREERARAKQASQRIINDDRDHGLEL
>CP022906.1|AXJ79539.1|48420_48597_-|hypothetical-protein
MIVSAVLLVVCLAIASFLIFHEQQIFPSLIFLGLAFIDGTKFYLSYQKLKERDHHGDN
>CP022906.1|AXJ79540.1|48593_48983_-|Bacterial-mobilization-protein-(MobC)
MSEQNTFVASDETVGRNRKPNRKAPKQISFRVSESEYLKLQQSAETLNMSVPAFVKKKAQGARLVAPKLDKATRQSVAKDLSMLGANANQIAKYCNQHQHEAPNYEALERNISELREMLDEIWKTLKEQ
>CP022906.1|AXJ79541.1|49251_49530_-|hypothetical-protein
MLLRETEDYEKYYKIGNVVMGTAFICIVIFSLMKSTPLPDLSFLKYIHFASEVLLIAGLIINSVPDFLTWNIKNIIFDLIIISFLIVFFIWV
>CP022906.1|AXJ79542.1|49626_50427_-|Teichoic-acid-translocation-permease-protein-TagG
MKSSLFILKEHFNNLYLMKRLAQFEMKISNKNNYLGTAWELINPSIQIFMYWFIFGLGFRNNRTVENIPFIFWLIVGISMWFFVNQGILNGTKAVTSKYKQVAKMNFPLSILSSYIVLSKFYTHVLLLILIMLICALNGYYPTIYTLQLLIFIPYTLLLTMTIALLTSTLAVIIRDVQMLMQALMRIIFFISSILYLPTNTLVLKVIQFNPIYFITESYRAAILYQNWFFITHWKLSLYNLAFLLITFVLGSLLHVKYREQFADFL
>CP022906.1|AXJ79543.1|52267_52441_+|FemAB-family-protein
MKFVTLTEQEYQLFIQKHAVHYTQSIAHYNYRQKYKKDVHLVGVKDNEEGSVAKLNL
>CP022906.1|AXJ79544.1|52470_53145_+|Integrase-core-domain-protein
MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRGRGVNVHHSTVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWLRKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLNNLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIMLAS
>CP022906.1|AXJ79545.1|53186_53549_-|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor
MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLEEAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAMYKIKSILKHGEKNGSVAK
>CP022906.1|AXJ79546.1|53824_54619_-|Aminoglycoside-3'-phosphotransferase
MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLKMTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEYEDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWEEDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKWYDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF
>CP022906.1|AXJ79547.1|54711_55254_-|TDP-fucosamine-acetyltransferase
MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEAPYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDIAVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDTMLYPNFENNFEKAVFWYLRF

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Crispr_ID: CP022906_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022906_2

417390-417490

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022906_2

>merge|CP022906|2|417390-417490|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>CP022906|2|2|417390-417490|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
CP022906.1\|AXJ79875.1\|425334_425871_-\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ79859.1\|408672_408924_+\|Transglycosylase-associated-protein	unknown	unknown	gnl\|CDD\|225170
CP022906.1\|AXJ79862.1\|410634_411261_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380196
CP022906.1\|AXJ79867.1\|415141_416530_-\|L-cystine-uptake-protein-TcyP	unknown	unknown	gnl\|CDD\|224736
CP022906.1\|AXJ79871.1\|420305_420884_+\|Xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
CP022906.1\|AXJ79858.1\|408109_408373_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238045
CP022906.1\|AXJ79864.1\|411705_413229_-\|Alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
CP022906.1\|AXJ79869.1\|418580_419243_-\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ79870.1\|419385_419793_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378584
CP022906.1\|AXJ79866.1\|414305_415061_+\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
CP022906.1\|AXJ79877.1\|427366_427639_-\|Transposase	unknown	unknown	gnl\|CDD\|225511
CP022906.1\|AXJ79860.1\|409349_409931_+\|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|223483
CP022906.1\|AXJ79872.1\|420883_422152_+\|Uric-acid-permease-PucK	unknown	unknown	gnl\|CDD\|274468
CP022906.1\|AXJ79861.1\|409996_410383_-\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ79868.1\|417506_418463_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235334
CP022906.1\|AXJ79863.1\|411333_411591_-\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ79874.1\|423680_425222_+\|GMP-synthase-[glutamine-hydrolyzing]	unknown	unknown	gnl\|CDD\|234614
CP022906.1\|AXJ79876.1\|426263_426968_-\|PemK-like-protein	unknown	unknown	gnl\|CDD\|367091
CP022906.1\|AXJ79865.1\|413244_413814_-\|Alkyl-hydroperoxide-reductase-subunit-C	unknown	unknown	gnl\|CDD\|211789
CP022906.1\|AXJ79873.1\|422189_423656_+\|Inosine-5'-monophosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|235507

Protein	Function_ID	Function_description	E-value
CP022906.1\|AXJ79859.1\|408672_408924_+\|Transglycosylase-associated-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.58864e-09
CP022906.1\|AXJ79873.1\|422189_423656_+\|Inosine-5'-monophosphate-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
CP022906.1\|AXJ79867.1\|415141_416530_-\|L-cystine-uptake-protein-TcyP	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
CP022906.1\|AXJ79871.1\|420305_420884_+\|Xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
CP022906.1\|AXJ79858.1\|408109_408373_-\|hypothetical-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.0037414
CP022906.1\|AXJ79864.1\|411705_413229_-\|Alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
CP022906.1\|AXJ79870.1\|419385_419793_-\|hypothetical-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.0219e-12
CP022906.1\|AXJ79866.1\|414305_415061_+\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	5.03864e-88
CP022906.1\|AXJ79877.1\|427366_427639_-\|Transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.23077e-11
CP022906.1\|AXJ79860.1\|409349_409931_+\|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.78414e-49
CP022906.1\|AXJ79872.1\|420883_422152_+\|Uric-acid-permease-PucK	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	2.75897e-170
CP022906.1\|AXJ79862.1\|410634_411261_-\|hypothetical-protein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.67126e-71
CP022906.1\|AXJ79868.1\|417506_418463_-\|hypothetical-protein	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.000748442
CP022906.1\|AXJ79874.1\|423680_425222_+\|GMP-synthase-[glutamine-hydrolyzing]	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
CP022906.1\|AXJ79876.1\|426263_426968_-\|PemK-like-protein	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	9.65175e-08
CP022906.1\|AXJ79865.1\|413244_413814_-\|Alkyl-hydroperoxide-reductase-subunit-C	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124

>CP022906.1|AXJ79867.1|415141_416530_-|L-cystine-uptake-protein-TcyP
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH
>CP022906.1|AXJ79866.1|414305_415061_+|NADPH-dependent-oxidoreductase
MSEHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>CP022906.1|AXJ79865.1|413244_413814_-|Alkyl-hydroperoxide-reductase-subunit-C
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>CP022906.1|AXJ79864.1|411705_413229_-|Alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDDKSKELKDLLTEITDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKKLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMNTGEEHLLNLDGIFVQIGLLPNTSWLNDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>CP022906.1|AXJ79863.1|411333_411591_-|hypothetical-protein
MLKVCTSRKQINMKNDIEKEKYVNEIIMLLRTIPTSKLVQPIMQLFIDKAILNNVQNDALLIEKATHARNHLRLWSLQGHRDIPN
>CP022906.1|AXJ79862.1|410634_411261_-|hypothetical-protein
MKKRLLLSTFLASTLILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>CP022906.1|AXJ79861.1|409996_410383_-|hypothetical-protein
MMKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNIIIMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFTSTIITLAIGGKSVEKNDSP
>CP022906.1|AXJ79860.1|409349_409931_+|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSRAEAVDLKVENCKPYIIE
>CP022906.1|AXJ79859.1|408672_408924_+|Transglycosylase-associated-protein
MFGFIGMLIVGGLIGWAAGAIMGKDIPGGILGNIIAGIIGSWVGGKLFGQWGPELGSIYILPALIGSIILIAIVTLILRAMRK
>CP022906.1|AXJ79858.1|408109_408373_-|hypothetical-protein
MNMHILYNLRTKHNLEIDELAQQLNEKYGTKYEAHQIWEWENHHHEPKFKDAMHLADFFDAPYEMFLESKVKEYQKHLEEVDIRMDK
>CP022906.1|AXJ79868.1|417506_418463_-|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKALAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNDNAAETSNKEATVDAEAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>CP022906.1|AXJ79869.1|418580_419243_-|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>CP022906.1|AXJ79870.1|419385_419793_-|hypothetical-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHQEVHENNSAYEEIDITHFAEASKGPKA
>CP022906.1|AXJ79871.1|420305_420884_+|Xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>CP022906.1|AXJ79872.1|420883_422152_+|Uric-acid-permease-PucK
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILLLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>CP022906.1|AXJ79873.1|422189_423656_+|Inosine-5'-monophosphate-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>CP022906.1|AXJ79874.1|423680_425222_+|GMP-synthase-[glutamine-hydrolyzing]
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>CP022906.1|AXJ79875.1|425334_425871_-|hypothetical-protein
MHNNNEFNKKLKDFIGSDKRMALVKGYVNEYKLTTVLRALNNSDYTKGTIHTRSIGNLKQIVDNRIIPKNITQNTIFKLSNLTLEVNLYERNTIYHGDFAIYYPVESALIIETDTPRLINHINNNPVQKIFIITTNDWSFNTLELEKIVDETIIYDLKQEDPKQYEILYKNKHGKLPY
>CP022906.1|AXJ79876.1|426263_426968_-|PemK-like-protein
MSKNINQANSKLNTSNKKLKQAYSKSDSKNMKVIYMPHWLEFYSIAIHSDVTSNKKRYYKSYSRGTVVYVKLGSNIGSEFSGNHFCVILDNKDNKGKETVTIVPLSSKGNKNYLKLNESVLNLTATDLKKQIIDISSKVQALAQKYREIDIKLSTEDKKLLSNLNQKANELYRVIGVYSKHKGKDTYVNISAITTISKRRISKINDSDPTGTIIISEDDMNEIEKQLKIKFFSN
>CP022906.1|AXJ79877.1|427366_427639_-|Transposase
MTKERRTFSSEFKLQMVRLYKNGKLKNEIIRKYDLKPSIISNSIKQHQNTGPFNHQDNLKSDEKELIKLRKEVQHLKMEHDVLKQILKLI

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Crispr_ID: CP022906_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022906_3

657919-658011

Orphan

Consensus_repeat	Method
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022906_3

>merge|CP022906|3|657919-658011|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTAAGGCACAACTGCATAAAAGCCTCTAATCGCTAAAGATGAAGAGGAACGCAGTTGGATGCTA

>CP022906|3|3|657919-658011|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	AGGCACAACTGCATAAAAGCCTCTAATCG
CTAAAGATGAAGAGGAACGCAGTTGGATGCTA

Protein	Signature genes	Signature genes Name	Protein_function
CP022906.1\|AXJ80078.1\|663311_664100_+\|Proline-iminopeptidase	unknown	unknown	gnl\|CDD\|223669
CP022906.1\|AXJ80081.1\|666796_667021_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378571
CP022906.1\|AXJ80068.1\|654403_654511_+\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ80067.1\|653318_654329_+\|Alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|181842
CP022906.1\|AXJ80063.1\|649754_650291_+\|Putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-YwqN	unknown	unknown	gnl\|CDD\|223728
CP022906.1\|AXJ80065.1\|650975_652271_+\|HD-domain-protein	unknown	unknown	gnl\|CDD\|224004
CP022906.1\|AXJ80069.1\|654603_655020_+\|putative-beta-barrel-protein-YwiB	unknown	unknown	gnl\|CDD\|226896
CP022906.1\|AXJ80076.1\|661758_662265_+\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ80073.1\|659078_660065_+\|putative-ABC-transporter-permease-protein	unknown	unknown	gnl\|CDD\|376439
CP022906.1\|AXJ80066.1\|652313_652820_+\|YwhD-family-protein	unknown	unknown	gnl\|CDD\|378039
CP022906.1\|AXJ80064.1\|650459_650936_+\|putative-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP022906.1\|AXJ80080.1\|665672_666602_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225778
CP022906.1\|AXJ80079.1\|664350_664725_-\|Transcriptional-regulator-SarA	unknown	unknown	gnl\|CDD\|130944
CP022906.1\|AXJ80072.1\|658079_658967_+\|Vitamin-B12-binding-protein-precursor	unknown	unknown	gnl\|CDD\|238563
CP022906.1\|AXJ80062.1\|648605_649544_+\|General-stress-protein-69	unknown	unknown	gnl\|CDD\|381309
CP022906.1\|AXJ80070.1\|655016_656678_+\|Arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
CP022906.1\|AXJ80071.1\|657065_657701_+\|endonuclease-III	unknown	unknown	gnl\|CDD\|225140
CP022906.1\|AXJ80074.1\|660119_660839_+\|(S)-2-haloacid-dehalogenase-4A	unknown	unknown	gnl\|CDD\|223943
CP022906.1\|AXJ80075.1\|660822_661623_+\|Haloacetate-dehalogenase-H-1	unknown	unknown	gnl\|CDD\|223669
CP022906.1\|AXJ80077.1\|662426_663143_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP022906.1\|AXJ80078.1\|663311_664100_+\|Proline-iminopeptidase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.55978e-34
CP022906.1\|AXJ80081.1\|666796_667021_-\|hypothetical-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	1.74707e-13
CP022906.1\|AXJ80066.1\|652313_652820_+\|YwhD-family-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	1.08203e-97
CP022906.1\|AXJ80067.1\|653318_654329_+\|Alcohol-dehydrogenase	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
CP022906.1\|AXJ80063.1\|649754_650291_+\|Putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-YwqN	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
CP022906.1\|AXJ80065.1\|650975_652271_+\|HD-domain-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
CP022906.1\|AXJ80069.1\|654603_655020_+\|putative-beta-barrel-protein-YwiB	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	2.62525e-58
CP022906.1\|AXJ80062.1\|648605_649544_+\|General-stress-protein-69	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	7.3194e-168
CP022906.1\|AXJ80064.1\|650459_650936_+\|putative-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
CP022906.1\|AXJ80079.1\|664350_664725_-\|Transcriptional-regulator-SarA	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
CP022906.1\|AXJ80072.1\|658079_658967_+\|Vitamin-B12-binding-protein-precursor	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	8.54601e-73
CP022906.1\|AXJ80073.1\|659078_660065_+\|putative-ABC-transporter-permease-protein	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	1.17074e-49
CP022906.1\|AXJ80070.1\|655016_656678_+\|Arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
CP022906.1\|AXJ80071.1\|657065_657701_+\|endonuclease-III	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	3.98158e-90
CP022906.1\|AXJ80074.1\|660119_660839_+\|(S)-2-haloacid-dehalogenase-4A	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
CP022906.1\|AXJ80075.1\|660822_661623_+\|Haloacetate-dehalogenase-H-1	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	7.17592e-26
CP022906.1\|AXJ80080.1\|665672_666602_-\|hypothetical-protein	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	7.93315e-37

>CP022906.1|AXJ80071.1|657065_657701_+|endonuclease-III
MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>CP022906.1|AXJ80070.1|655016_656678_+|Arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEVRLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>CP022906.1|AXJ80069.1|654603_655020_+|putative-beta-barrel-protein-YwiB
MDKKVSIQTKQVLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>CP022906.1|AXJ80068.1|654403_654511_+|hypothetical-protein
MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN
>CP022906.1|AXJ80067.1|653318_654329_+|Alcohol-dehydrogenase
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>CP022906.1|AXJ80066.1|652313_652820_+|YwhD-family-protein
MSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>CP022906.1|AXJ80065.1|650975_652271_+|HD-domain-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>CP022906.1|AXJ80064.1|650459_650936_+|putative-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>CP022906.1|AXJ80063.1|649754_650291_+|Putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-YwqN
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>CP022906.1|AXJ80062.1|648605_649544_+|General-stress-protein-69
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDNNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVVENIKAADIVLSDDEIQYIDELFPIED
>CP022906.1|AXJ80072.1|658079_658967_+|Vitamin-B12-binding-protein-precursor
MKKSLIAFILIFMLVLSGCGMKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>CP022906.1|AXJ80073.1|659078_660065_+|putative-ABC-transporter-permease-protein
MNVIIDERKENAMTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVTGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>CP022906.1|AXJ80074.1|660119_660839_+|(S)-2-haloacid-dehalogenase-4A
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>CP022906.1|AXJ80075.1|660822_661623_+|Haloacetate-dehalogenase-H-1
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLTLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTAAFINKHHDEKHV
>CP022906.1|AXJ80076.1|661758_662265_+|hypothetical-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>CP022906.1|AXJ80077.1|662426_663143_+|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>CP022906.1|AXJ80078.1|663311_664100_+|Proline-iminopeptidase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLKFLKSVS
>CP022906.1|AXJ80079.1|664350_664725_-|Transcriptional-regulator-SarA
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>CP022906.1|AXJ80080.1|665672_666602_-|hypothetical-protein
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIILNIIINPEVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIVGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSIALLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>CP022906.1|AXJ80081.1|666796_667021_-|hypothetical-protein
MTKTLELSFKSSLDKPVKLQLPQLNNVVTEQVARDSMNALVDLNIIKSNSGTITKVHSAQIIDKTTTVLFEDKK

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Crispr_ID: CP022906_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022906_4

816310-816390

Unclear

Consensus_repeat	Method
TTCTTTATGTTGGGGCCCCGCCAACT	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of CP022906_4

>merge|CP022906|4|816310-816390|CRISPRCasFinder
TTCTTTATGTTGGGGCCCCGCCAACTTGCATTGTTTGTAGAATTTCTTTTCGAAATTCTTTATGTTGGGGCCCCGCCAACT

>CP022906|4|4|816310-816390|CRISPRCasFinder
TTCTTTATGTTGGGGCCCCGCCAACT	TGCATTGTTTGTAGAATTTCTTTTCGAAA
TTCTTTATGTTGGGGCCCCGCCAACT

Protein	Signature genes	Signature genes Name	Protein_function
CP022906.1\|AXJ80221.1\|817564_818404_+\|Prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
CP022906.1\|AXJ80213.1\|804650_807182_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
CP022906.1\|AXJ80226.1\|823075_824071_+\|Gluconeogenesis-factor	unknown	unknown	gnl\|CDD\|211689
CP022906.1\|AXJ80219.1\|813173_816020_+\|UvrABC-system-protein-A	unknown	unknown	gnl\|CDD\|234734
CP022906.1\|AXJ80210.1\|801854_802937_+\|primosome-assembly-protein-PriA	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|226583
CP022906.1\|AXJ80211.1\|802929_803604_+\|DNA-utilization-protein-GntX	unknown	unknown	gnl\|CDD\|223970
CP022906.1\|AXJ80228.1\|825697_826285_+\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|178955
CP022906.1\|AXJ80214.1\|807614_808607_+\|Peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
CP022906.1\|AXJ80223.1\|818904_820344_+\|Tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
CP022906.1\|AXJ80217.1\|810675_810912_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227234
CP022906.1\|AXJ80222.1\|818411_818897_+\|Maltose-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100053
CP022906.1\|AXJ80220.1\|816626_817559_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
CP022906.1\|AXJ80229.1\|826527_827397_-\|Epimerase-family-protein	unknown	unknown	gnl\|CDD\|224015
CP022906.1\|AXJ80224.1\|820410_821346_+\|Thioredoxin-reductase	unknown	unknown	gnl\|CDD\|273540
CP022906.1\|AXJ80218.1\|811180_813166_+\|UvrABC-system-protein-B	unknown	unknown	gnl\|CDD\|235395
CP022906.1\|AXJ80227.1\|824180_825125_+\|Putative-sporulation-transcription-regulator-WhiA	unknown	unknown	gnl\|CDD\|273194
CP022906.1\|AXJ80225.1\|822167_823079_+\|glmZ(sRNA)-inactivating-NTPase	unknown	unknown	gnl\|CDD\|224574
CP022906.1\|AXJ80216.1\|810028_810679_+\|5'-deoxynucleotidase-YfbR	unknown	unknown	gnl\|CDD\|378993
CP022906.1\|AXJ80212.1\|803664_804237_+\|Putative-sigma-54-modulation-protein	unknown	unknown	gnl\|CDD\|224461
CP022906.1\|AXJ80215.1\|809015_809855_+\|Secretory-antigen-SsaA-precursor	unknown	unknown	gnl\|CDD\|226451

Protein	Function_ID	Function_description	E-value
CP022906.1\|AXJ80221.1\|817564_818404_+\|Prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.39921e-119
CP022906.1\|AXJ80213.1\|804650_807182_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
CP022906.1\|AXJ80226.1\|823075_824071_+\|Gluconeogenesis-factor	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
CP022906.1\|AXJ80219.1\|813173_816020_+\|UvrABC-system-protein-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP022906.1\|AXJ80210.1\|801854_802937_+\|primosome-assembly-protein-PriA	gnl\|CDD\|226583	COG4098, comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair].	1.55868e-179
CP022906.1\|AXJ80211.1\|802929_803604_+\|DNA-utilization-protein-GntX	gnl\|CDD\|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	7.54382e-50
CP022906.1\|AXJ80228.1\|825697_826285_+\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
CP022906.1\|AXJ80214.1\|807614_808607_+\|Peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
CP022906.1\|AXJ80223.1\|818904_820344_+\|Tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.50708e-06
CP022906.1\|AXJ80217.1\|810675_810912_+\|hypothetical-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
CP022906.1\|AXJ80222.1\|818411_818897_+\|Maltose-O-acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
CP022906.1\|AXJ80220.1\|816626_817559_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
CP022906.1\|AXJ80229.1\|826527_827397_-\|Epimerase-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	1.35317e-146
CP022906.1\|AXJ80224.1\|820410_821346_+\|Thioredoxin-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
CP022906.1\|AXJ80218.1\|811180_813166_+\|UvrABC-system-protein-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP022906.1\|AXJ80227.1\|824180_825125_+\|Putative-sporulation-transcription-regulator-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
CP022906.1\|AXJ80225.1\|822167_823079_+\|glmZ(sRNA)-inactivating-NTPase	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
CP022906.1\|AXJ80216.1\|810028_810679_+\|5'-deoxynucleotidase-YfbR	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
CP022906.1\|AXJ80212.1\|803664_804237_+\|Putative-sigma-54-modulation-protein	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
CP022906.1\|AXJ80215.1\|809015_809855_+\|Secretory-antigen-SsaA-precursor	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	2.23913e-42

>CP022906.1|AXJ80219.1|813173_816020_+|UvrABC-system-protein-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>CP022906.1|AXJ80218.1|811180_813166_+|UvrABC-system-protein-B
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>CP022906.1|AXJ80217.1|810675_810912_+|hypothetical-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>CP022906.1|AXJ80216.1|810028_810679_+|5'-deoxynucleotidase-YfbR
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>CP022906.1|AXJ80215.1|809015_809855_+|Secretory-antigen-SsaA-precursor
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVTKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>CP022906.1|AXJ80214.1|807614_808607_+|Peptide-chain-release-factor-2
MAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>CP022906.1|AXJ80213.1|804650_807182_+|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>CP022906.1|AXJ80212.1|803664_804237_+|Putative-sigma-54-modulation-protein
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>CP022906.1|AXJ80211.1|802929_803604_+|DNA-utilization-protein-GntX
MNNCLSCGAKLYENITIYNLFKKPNRLCDRCKENWDNIKLDIKARRCSRWLKHLNQDEAYCLDCKFLSAHFNLMEQLYCQFQYDGLMKEMIHQYKFLKDYYLCELLAHLIEIPQTSYDYIVPIPSSPAHDLSRTFNPVEAVLKAKGIRFDKILKMSNRPKQSHLTKKERLADENPFIIDTELDLNGKEILLVDDIYTTGLTIHRAGCKLYAKNIRKFKVFAFAR
>CP022906.1|AXJ80210.1|801854_802937_+|primosome-assembly-protein-PriA
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRKRQTILLYAVTGAGKTEMMFQGIQYARIQGDNIAIVSPRVDVVVEISKRIKDAFLNEDIDILHQQSRQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKNLQQALKSSSKVEHATIYMTATPPKQLLSEIPHENIIKLPARFHKKSLPVPKYRYFKLNNKKIQKMLYRILQDQINNQRYTLVFFNNIETMIKTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKLECPTGKVLFFHEGVSMNMIQAKKEIQRMNKLALKRGWIDE
>CP022906.1|AXJ80220.1|816626_817559_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>CP022906.1|AXJ80221.1|817564_818404_+|Prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGSVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>CP022906.1|AXJ80222.1|818411_818897_+|Maltose-O-acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP022906.1|AXJ80223.1|818904_820344_+|Tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDMEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDRAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVSENDVMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP022906.1|AXJ80224.1|820410_821346_+|Thioredoxin-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>CP022906.1|AXJ80225.1|822167_823079_+|glmZ(sRNA)-inactivating-NTPase
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>CP022906.1|AXJ80226.1|823075_824071_+|Gluconeogenesis-factor
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>CP022906.1|AXJ80227.1|824180_825125_+|Putative-sporulation-transcription-regulator-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>CP022906.1|AXJ80228.1|825697_826285_+|ATP-dependent-Clp-protease-proteolytic-subunit
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>CP022906.1|AXJ80229.1|826527_827397_-|Epimerase-family-protein
MVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKALFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE

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Crispr_ID: CP022906_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022906_5

821708-821793

Unclear

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022906_5

>merge|CP022906|5|821708-821793|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>CP022906|5|5|821708-821793|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	CCGCCAGCTTCTGTGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
CP022906.1\|AXJ80221.1\|817564_818404_+\|Prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
CP022906.1\|AXJ80231.1\|829522_830536_+\|Central-glycolytic-genes-regulator	unknown	unknown	gnl\|CDD\|225263
CP022906.1\|AXJ80226.1\|823075_824071_+\|Gluconeogenesis-factor	unknown	unknown	gnl\|CDD\|211689
CP022906.1\|AXJ80219.1\|813173_816020_+\|UvrABC-system-protein-A	unknown	unknown	gnl\|CDD\|234734
CP022906.1\|AXJ80232.1\|830588_831599_+\|Glyceraldehyde-3-phosphate-dehydrogenase-1	unknown	unknown	gnl\|CDD\|273675
CP022906.1\|AXJ80230.1\|828133_828763_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234750
CP022906.1\|AXJ80223.1\|818904_820344_+\|Tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
CP022906.1\|AXJ80217.1\|810675_810912_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227234
CP022906.1\|AXJ80222.1\|818411_818897_+\|Maltose-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100053
CP022906.1\|AXJ80220.1\|816626_817559_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
CP022906.1\|AXJ80229.1\|826527_827397_-\|Epimerase-family-protein	unknown	unknown	gnl\|CDD\|224015
CP022906.1\|AXJ80224.1\|820410_821346_+\|Thioredoxin-reductase	unknown	unknown	gnl\|CDD\|273540
CP022906.1\|AXJ80218.1\|811180_813166_+\|UvrABC-system-protein-B	unknown	unknown	gnl\|CDD\|235395
CP022906.1\|AXJ80227.1\|824180_825125_+\|Putative-sporulation-transcription-regulator-WhiA	unknown	unknown	gnl\|CDD\|273194
CP022906.1\|AXJ80225.1\|822167_823079_+\|glmZ(sRNA)-inactivating-NTPase	unknown	unknown	gnl\|CDD\|224574
CP022906.1\|AXJ80216.1\|810028_810679_+\|5'-deoxynucleotidase-YfbR	unknown	unknown	gnl\|CDD\|378993
CP022906.1\|AXJ80228.1\|825697_826285_+\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|178955
CP022906.1\|AXJ80234.1\|833049_833811_+\|Triosephosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
CP022906.1\|AXJ80215.1\|809015_809855_+\|Secretory-antigen-SsaA-precursor	unknown	unknown	gnl\|CDD\|226451
CP022906.1\|AXJ80233.1\|831737_832928_+\|Phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613

Protein	Function_ID	Function_description	E-value
CP022906.1\|AXJ80221.1\|817564_818404_+\|Prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.39921e-119
CP022906.1\|AXJ80231.1\|829522_830536_+\|Central-glycolytic-genes-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92
CP022906.1\|AXJ80226.1\|823075_824071_+\|Gluconeogenesis-factor	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
CP022906.1\|AXJ80219.1\|813173_816020_+\|UvrABC-system-protein-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP022906.1\|AXJ80232.1\|830588_831599_+\|Glyceraldehyde-3-phosphate-dehydrogenase-1	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
CP022906.1\|AXJ80230.1\|828133_828763_+\|hypothetical-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.85535e-05
CP022906.1\|AXJ80223.1\|818904_820344_+\|Tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.50708e-06
CP022906.1\|AXJ80217.1\|810675_810912_+\|hypothetical-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
CP022906.1\|AXJ80222.1\|818411_818897_+\|Maltose-O-acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
CP022906.1\|AXJ80220.1\|816626_817559_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
CP022906.1\|AXJ80229.1\|826527_827397_-\|Epimerase-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	1.35317e-146
CP022906.1\|AXJ80224.1\|820410_821346_+\|Thioredoxin-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
CP022906.1\|AXJ80218.1\|811180_813166_+\|UvrABC-system-protein-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP022906.1\|AXJ80227.1\|824180_825125_+\|Putative-sporulation-transcription-regulator-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
CP022906.1\|AXJ80225.1\|822167_823079_+\|glmZ(sRNA)-inactivating-NTPase	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
CP022906.1\|AXJ80216.1\|810028_810679_+\|5'-deoxynucleotidase-YfbR	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
CP022906.1\|AXJ80228.1\|825697_826285_+\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
CP022906.1\|AXJ80234.1\|833049_833811_+\|Triosephosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.84083e-146
CP022906.1\|AXJ80215.1\|809015_809855_+\|Secretory-antigen-SsaA-precursor	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	2.23913e-42
CP022906.1\|AXJ80233.1\|831737_832928_+\|Phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0

>CP022906.1|AXJ80224.1|820410_821346_+|Thioredoxin-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>CP022906.1|AXJ80223.1|818904_820344_+|Tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDMEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDRAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVSENDVMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP022906.1|AXJ80222.1|818411_818897_+|Maltose-O-acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP022906.1|AXJ80221.1|817564_818404_+|Prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGSVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>CP022906.1|AXJ80220.1|816626_817559_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>CP022906.1|AXJ80219.1|813173_816020_+|UvrABC-system-protein-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>CP022906.1|AXJ80218.1|811180_813166_+|UvrABC-system-protein-B
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>CP022906.1|AXJ80217.1|810675_810912_+|hypothetical-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>CP022906.1|AXJ80216.1|810028_810679_+|5'-deoxynucleotidase-YfbR
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>CP022906.1|AXJ80215.1|809015_809855_+|Secretory-antigen-SsaA-precursor
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVTKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>CP022906.1|AXJ80225.1|822167_823079_+|glmZ(sRNA)-inactivating-NTPase
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>CP022906.1|AXJ80226.1|823075_824071_+|Gluconeogenesis-factor
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>CP022906.1|AXJ80227.1|824180_825125_+|Putative-sporulation-transcription-regulator-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>CP022906.1|AXJ80228.1|825697_826285_+|ATP-dependent-Clp-protease-proteolytic-subunit
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>CP022906.1|AXJ80229.1|826527_827397_-|Epimerase-family-protein
MVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKALFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>CP022906.1|AXJ80230.1|828133_828763_+|hypothetical-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDKASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>CP022906.1|AXJ80231.1|829522_830536_+|Central-glycolytic-genes-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>CP022906.1|AXJ80232.1|830588_831599_+|Glyceraldehyde-3-phosphate-dehydrogenase-1
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>CP022906.1|AXJ80233.1|831737_832928_+|Phosphoglycerate-kinase
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>CP022906.1|AXJ80234.1|833049_833811_+|Triosephosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK

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Crispr_ID: CP022906_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022906_6

866312-866393

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022906_6

>merge|CP022906|6|866312-866393|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>CP022906|6|6|866312-866393|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP022906.1\|AXJ80276.1\|870569_871790_-\|Transposase	unknown	unknown	gnl\|CDD\|271189
CP022906.1\|AXJ80269.1\|865214_865328_+\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ80266.1\|863792_864113_-\|Thioredoxin-like-protein-YdbP	unknown	unknown	gnl\|CDD\|239245
CP022906.1\|AXJ80272.1\|867328_867625_+\|Thioredoxin	unknown	unknown	gnl\|CDD\|239245
CP022906.1\|AXJ80270.1\|865329_866208_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226395
CP022906.1\|AXJ80277.1\|871878_872607_-\|Enterotoxin-type-A-precursor	unknown	unknown	gnl\|CDD\|280949
CP022906.1\|AXJ80278.1\|872910_873360_-\|Enterotoxin-type-E-precursor	unknown	unknown	unknown
CP022906.1\|AXJ80274.1\|868892_869588_+\|Methionine-import-system-permease-protein-MetP	unknown	unknown	gnl\|CDD\|224922
CP022906.1\|AXJ80271.1\|866946_867336_+\|Ribonuclease-M5	unknown	unknown	gnl\|CDD\|224572
CP022906.1\|AXJ80262.1\|860841_861336_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372596
CP022906.1\|AXJ80279.1\|873429_873861_-\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ80280.1\|873877_874336_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368753
CP022906.1\|AXJ80263.1\|861734_862157_-\|Organic-hydroperoxide-resistance-protein-like-protein	unknown	unknown	gnl\|CDD\|274649
CP022906.1\|AXJ80265.1\|863103_863643_+\|putative-oxidoreductase	unknown	unknown	gnl\|CDD\|380312
CP022906.1\|AXJ80275.1\|869605_870427_+\|Methionine-binding-lipoprotein-MetQ-precursor	unknown	unknown	gnl\|CDD\|224381
CP022906.1\|AXJ80273.1\|867874_868900_+\|Methionine-import-ATP-binding-protein-MetN-2	unknown	unknown	gnl\|CDD\|224058
CP022906.1\|AXJ80268.1\|864770_865151_+\|Glycine-cleavage-system-H-protein	unknown	unknown	gnl\|CDD\|234918
CP022906.1\|AXJ80267.1\|864256_864613_+\|Regulatory-protein-MgsR	unknown	unknown	gnl\|CDD\|239334
CP022906.1\|AXJ80264.1\|862304_863021_+\|3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
CP022906.1\|AXJ80261.1\|860069_860687_-\|Arginine-exporter-protein-ArgO	unknown	unknown	gnl\|CDD\|224198

Protein	Function_ID	Function_description	E-value
CP022906.1\|AXJ80276.1\|870569_871790_-\|Transposase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	6.11443e-38
CP022906.1\|AXJ80266.1\|863792_864113_-\|Thioredoxin-like-protein-YdbP	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.70086e-24
CP022906.1\|AXJ80272.1\|867328_867625_+\|Thioredoxin	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
CP022906.1\|AXJ80270.1\|865329_866208_+\|hypothetical-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.16579e-75
CP022906.1\|AXJ80277.1\|871878_872607_-\|Enterotoxin-type-A-precursor	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	1.08384e-24
CP022906.1\|AXJ80274.1\|868892_869588_+\|Methionine-import-system-permease-protein-MetP	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
CP022906.1\|AXJ80271.1\|866946_867336_+\|Ribonuclease-M5	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	6.789e-37
CP022906.1\|AXJ80262.1\|860841_861336_-\|hypothetical-protein	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
CP022906.1\|AXJ80280.1\|873877_874336_-\|hypothetical-protein	gnl\|CDD\|368753	pfam06114, Peptidase_M78, IrrE N-terminal-like domain. This entry includes the catalytic domain of the protein ImmA, which is a metallopeptidase containing an HEXXH zinc-binding motif from peptidase family M78. ImmA is encoded on a conjugative transposon. Conjugating bacteria are able to transfer conjugative transposons that can, for example, confer resistance to antibiotics. The transposon is integrated into the chromosome, but during conjugation excises itself and then moves to the recipient bacterium and re-integrate into its chromosome. Typically a conjugative tranposon encodes only the proteins required for this activity and the proteins that regulate it. During exponential growth, the ICEBs1 transposon of Bacillus subtilis is inactivated by the immunity repressor protein ImmR, which is encoded by the transposon and represses the genes for excision and transfer. Cleavage of ImmR relaxes repression and allows transfer of the transposon. ImmA has been shown to be essential for the cleavage of ImmR. This domain is also found in in metalloprotease IrrE, a central regulator of DNA damage repair in Deinococcaceae, HTH-type transcriptional regulators RamB and PrpC.	0.00011929
CP022906.1\|AXJ80263.1\|861734_862157_-\|Organic-hydroperoxide-resistance-protein-like-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
CP022906.1\|AXJ80265.1\|863103_863643_+\|putative-oxidoreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	1.47647e-49
CP022906.1\|AXJ80275.1\|869605_870427_+\|Methionine-binding-lipoprotein-MetQ-precursor	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112
CP022906.1\|AXJ80273.1\|867874_868900_+\|Methionine-import-ATP-binding-protein-MetN-2	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
CP022906.1\|AXJ80268.1\|864770_865151_+\|Glycine-cleavage-system-H-protein	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	2.81086e-68
CP022906.1\|AXJ80267.1\|864256_864613_+\|Regulatory-protein-MgsR	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
CP022906.1\|AXJ80264.1\|862304_863021_+\|3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.26721e-148
CP022906.1\|AXJ80261.1\|860069_860687_-\|Arginine-exporter-protein-ArgO	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	2.05663e-61

>CP022906.1|AXJ80270.1|865329_866208_+|hypothetical-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDDLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>CP022906.1|AXJ80269.1|865214_865328_+|hypothetical-protein
MKEKLLGTIIWSIATFYYSRMMEIMNLAILKIKIGGS
>CP022906.1|AXJ80268.1|864770_865151_+|Glycine-cleavage-system-H-protein
MAVPNELKYSKEHEWVKVEGNVAIIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
>CP022906.1|AXJ80267.1|864256_864613_+|Regulatory-protein-MgsR
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>CP022906.1|AXJ80266.1|863792_864113_-|Thioredoxin-like-protein-YdbP
MQSIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>CP022906.1|AXJ80265.1|863103_863643_+|putative-oxidoreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEGDMPKAPRKNRNLITLY
>CP022906.1|AXJ80264.1|862304_863021_+|3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGVPQAPGQIDVTDLKAQVTLY
>CP022906.1|AXJ80263.1|861734_862157_-|Organic-hydroperoxide-resistance-protein-like-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>CP022906.1|AXJ80262.1|860841_861336_-|hypothetical-protein
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>CP022906.1|AXJ80261.1|860069_860687_-|Arginine-exporter-protein-ArgO
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITARLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGETQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF
>CP022906.1|AXJ80271.1|866946_867336_+|Ribonuclease-M5
MMAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>CP022906.1|AXJ80272.1|867328_867625_+|Thioredoxin
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>CP022906.1|AXJ80273.1|867874_868900_+|Methionine-import-ATP-binding-protein-MetN-2
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>CP022906.1|AXJ80274.1|868892_869588_+|Methionine-import-system-permease-protein-MetP
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>CP022906.1|AXJ80275.1|869605_870427_+|Methionine-binding-lipoprotein-MetQ-precursor
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>CP022906.1|AXJ80276.1|870569_871790_-|Transposase
MWLEKFKNKNKETKYRYYEKYKDPLTAKWRRVSVVLNKNGKQSQKEAQRLLNERIEAKLNDKTPTTLKSLTFHVACDEWFQSYIKTSGSKRTTIKTKLSKLNTLKKFVDEDILINKITLSYAQQVFDEMDNKGYVYQVNKDALSIFKNVFEYTRRIYKLQDLEFLKDITLNKRIKSYDEVKAKRNKYLELNEIQSIIKDINTKAQKMHSGIHKRFYLFVALMTEFQALNGMRIGEMLAIQNEDIDFDNKSLNINGTIHWFHDESGGFGVKDTTKTESSYRTIGLSSRSCEILKKAILENKKDSKWNDGYLNRNFVFTNHKGNPMQTERFNKILREAAKDVGIDKEVSSHILRHSHISLLSQQGVSLKAIMDRVGHSDHRTTLSIYSHVTEQMDKDMMNKLEQVKLG
>CP022906.1|AXJ80277.1|871878_872607_-|Enterotoxin-type-A-precursor
MKKLISILLINIIILGVSNSASAQGDIGIDNLRNFYTKKDFVDLKDVKDNDTPIANQLQFSNESYDLISESKDFNKFSNFKGKKLDVFGISYNGQCNTKYIYGGVTATNEYLDKSRNIPINIWINGNHKTISTNKVSTNKKFVTAQEIDVKLRKYLQEEYNIYGHNGTKKGEEYGHKSKFYSGFNIGKVTFHLNNNDTFSYDLFYTGDDGLPKSFLKIYEDNKTVESEKFHLDVDISYKETI
>CP022906.1|AXJ80278.1|872910_873360_-|Enterotoxin-type-E-precursor
MNKIFRILTVSLFFFTFLIKNNLAYADVGVINLRNFYANYEPEKLQGVSSGNFSTSHQLEYIDGKYTLYSQFHNEYEAKRLKDHKVDIFGISYSGLCNTKYMYGGITLANQNLDKPRNIPINLWVNGKQNTISTDKVSTQKKRGNCSRD
>CP022906.1|AXJ80279.1|873429_873861_-|hypothetical-protein
MRKLLGLALASTLILGACGSNDGDKKEESKSYTTNDIVKGFKDNKLNVINEKEMTREDFGLAPMKTDEAKMFVVQDDKNARVMKFKNSDDLKQTKKYYDELGKESAAFYSHTHSKGKFLIQMNGDIDDATFNKYKNSMDKTLK
>CP022906.1|AXJ80280.1|873877_874336_-|hypothetical-protein
MYLYEKMVIENKEIPIDDGKSLGNFEGLYDNGVILINKNLSERRKAEVLYEELAHHKLTYGNILDQSKFNNRKFENYARRHGFISAVPLREIVEAYNYGVRNLYELSEYLQLSEEYILEAIEQYKKIYGIGTHYGEYSITFEPLRVFKYKEI

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Crispr_ID: CP022906_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022906_7

931101-931383

Orphan

Consensus_repeat	Method
AAAGNCAGCTNNNNANANNNTGCAAGTTGG	CRT

4 spacers

The CRISPR arrays of CP022906_7

>merge|CP022906|7|931101-931383|CRT
AAAGTCAGCTTACAATAGTGTGCAAGTTGGCGGGGCCCCAACACAGAGGCTGGCGGAAAGTCAGCTTACAATAGTGTGCAAGTTGGGGTGGAGCCCCGACACAGAGAAATTAGCTCCTCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGCGAAAAGTCAGCTTACAATAGTGTGCAAGTTGGGGTGGGACGACGAAATAAATTTTGCGAAAATATCATTTCTGTCCCACTCCCAAAAAGACAGCAGTAGGATAATTTCAATTTGG

>CP022906|7|1|931101-931383|CRT
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	CGGGGCCCCAACACAGAGGCTGGCGG
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	GGTGGAGCCCCGACACAGAGAAATTAGC
TCCTCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACACAGAAGCTGGCGA
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	GGTGGGACGACGAAATAAATTTTGCGAAAATATCATTTCTGTCCCACTCCCAA
AAAGACAGCAGTAGGATAATTTCAATTTGG

Protein	Signature genes	Signature genes Name	Protein_function
CP022906.1\|AXJ80359.1\|946355_947258_+\|Ureidoglycolate-lyase	unknown	unknown	gnl\|CDD\|223257
CP022906.1\|AXJ80341.1\|921479_921821_-\|Na(+)/H(+)-antiporter-subunit-C1	unknown	unknown	gnl\|CDD\|181497
CP022906.1\|AXJ80355.1\|937784_938309_+\|Signal-peptidase-IB	unknown	unknown	gnl\|CDD\|274044
CP022906.1\|AXJ80351.1\|932623_934003_-\|Argininosuccinate-lyase-1	unknown	unknown	gnl\|CDD\|179143
CP022906.1\|AXJ80357.1\|939059_942536_+\|ATP-dependent-helicase/deoxyribonuclease-subunit-B	unknown	unknown	gnl\|CDD\|213736
CP022906.1\|AXJ80346.1\|926233_926611_+\|General-stress-protein-13	unknown	unknown	gnl\|CDD\|224023
CP022906.1\|AXJ80353.1\|935548_936880_+\|Glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
CP022906.1\|AXJ80356.1\|938324_938900_+\|Signal-peptidase-IB	unknown	unknown	gnl\|CDD\|274044
CP022906.1\|AXJ80349.1\|929705_930950_+\|NAD-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
CP022906.1\|AXJ80354.1\|937204_937780_+\|TVP38/TMEM64-family-inner-membrane-protein-YdjZ	unknown	unknown	gnl\|CDD\|223475
CP022906.1\|AXJ80340.1\|919990_921487_-\|Na(+)/H(+)-antiporter-subunit-D1	unknown	unknown	gnl\|CDD\|181085
CP022906.1\|AXJ80342.1\|921820_922249_-\|Na(+)/H(+)-antiporter-subunit-B1	unknown	unknown	gnl\|CDD\|183602
CP022906.1\|AXJ80348.1\|928406_929597_+\|Ornithine-aminotransferase-2	unknown	unknown	gnl\|CDD\|179736
CP022906.1\|AXJ80345.1\|925224_925818_+\|Putative-peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|238908
CP022906.1\|AXJ80358.1\|942536_946190_+\|ATP-dependent-helicase/nuclease-subunit-A	unknown	unknown	gnl\|CDD\|274299
CP022906.1\|AXJ80343.1\|922241_924647_-\|Na(+)/H(+)-antiporter-subunit-A1	unknown	unknown	gnl\|CDD\|237155
CP022906.1\|AXJ80344.1\|924777_925161_-\|Kinase-associated-lipoprotein-B-precursor	unknown	unknown	gnl\|CDD\|378054
CP022906.1\|AXJ80352.1\|933992_935198_-\|Argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
CP022906.1\|AXJ80350.1\|931452_932382_-\|putative-glycerophosphoryl-diester-phosphodiesterase-1	unknown	unknown	gnl\|CDD\|176543
CP022906.1\|AXJ80347.1\|926971_928099_+\|NADH-oxidase	unknown	unknown	gnl\|CDD\|240086

Protein	Function_ID	Function_description	E-value
CP022906.1\|AXJ80359.1\|946355_947258_+\|Ureidoglycolate-lyase	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.0042e-87
CP022906.1\|AXJ80341.1\|921479_921821_-\|Na(+)/H(+)-antiporter-subunit-C1	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	9.82501e-64
CP022906.1\|AXJ80355.1\|937784_938309_+\|Signal-peptidase-IB	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.63848e-48
CP022906.1\|AXJ80351.1\|932623_934003_-\|Argininosuccinate-lyase-1	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
CP022906.1\|AXJ80357.1\|939059_942536_+\|ATP-dependent-helicase/deoxyribonuclease-subunit-B	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
CP022906.1\|AXJ80346.1\|926233_926611_+\|General-stress-protein-13	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
CP022906.1\|AXJ80353.1\|935548_936880_+\|Glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
CP022906.1\|AXJ80356.1\|938324_938900_+\|Signal-peptidase-IB	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	4.05406e-53
CP022906.1\|AXJ80349.1\|929705_930950_+\|NAD-specific-glutamate-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
CP022906.1\|AXJ80354.1\|937204_937780_+\|TVP38/TMEM64-family-inner-membrane-protein-YdjZ	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.01759e-40
CP022906.1\|AXJ80340.1\|919990_921487_-\|Na(+)/H(+)-antiporter-subunit-D1	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
CP022906.1\|AXJ80342.1\|921820_922249_-\|Na(+)/H(+)-antiporter-subunit-B1	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
CP022906.1\|AXJ80348.1\|928406_929597_+\|Ornithine-aminotransferase-2	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
CP022906.1\|AXJ80345.1\|925224_925818_+\|Putative-peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
CP022906.1\|AXJ80358.1\|942536_946190_+\|ATP-dependent-helicase/nuclease-subunit-A	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
CP022906.1\|AXJ80343.1\|922241_924647_-\|Na(+)/H(+)-antiporter-subunit-A1	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
CP022906.1\|AXJ80344.1\|924777_925161_-\|Kinase-associated-lipoprotein-B-precursor	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	1.89892e-52
CP022906.1\|AXJ80352.1\|933992_935198_-\|Argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
CP022906.1\|AXJ80350.1\|931452_932382_-\|putative-glycerophosphoryl-diester-phosphodiesterase-1	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	5.11302e-151
CP022906.1\|AXJ80347.1\|926971_928099_+\|NADH-oxidase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0

>CP022906.1|AXJ80349.1|929705_930950_+|NAD-specific-glutamate-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>CP022906.1|AXJ80348.1|928406_929597_+|Ornithine-aminotransferase-2
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>CP022906.1|AXJ80347.1|926971_928099_+|NADH-oxidase
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSNIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPVAVIEEVLKAKEAYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>CP022906.1|AXJ80346.1|926233_926611_+|General-stress-protein-13
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>CP022906.1|AXJ80345.1|925224_925818_+|Putative-peptidyl-prolyl-cis-trans-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>CP022906.1|AXJ80344.1|924777_925161_-|Kinase-associated-lipoprotein-B-precursor
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHDRKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>CP022906.1|AXJ80343.1|922241_924647_-|Na(+)/H(+)-antiporter-subunit-A1
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>CP022906.1|AXJ80342.1|921820_922249_-|Na(+)/H(+)-antiporter-subunit-B1
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>CP022906.1|AXJ80341.1|921479_921821_-|Na(+)/H(+)-antiporter-subunit-C1
MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>CP022906.1|AXJ80340.1|919990_921487_-|Na(+)/H(+)-antiporter-subunit-D1
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK
>CP022906.1|AXJ80350.1|931452_932382_-|putative-glycerophosphoryl-diester-phosphodiesterase-1
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>CP022906.1|AXJ80351.1|932623_934003_-|Argininosuccinate-lyase-1
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>CP022906.1|AXJ80352.1|933992_935198_-|Argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>CP022906.1|AXJ80353.1|935548_936880_+|Glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>CP022906.1|AXJ80354.1|937204_937780_+|TVP38/TMEM64-family-inner-membrane-protein-YdjZ
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE
>CP022906.1|AXJ80355.1|937784_938309_+|Signal-peptidase-IB
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDQDNNKHDSRQFGLIDKKDIIGNVSLRYYPFSKWTVQFKS
>CP022906.1|AXJ80356.1|938324_938900_+|Signal-peptidase-IB
MKKEILEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>CP022906.1|AXJ80357.1|939059_942536_+|ATP-dependent-helicase/deoxyribonuclease-subunit-B
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKGHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>CP022906.1|AXJ80358.1|942536_946190_+|ATP-dependent-helicase/nuclease-subunit-A
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDSVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYRYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>CP022906.1|AXJ80359.1|946355_947258_+|Ureidoglycolate-lyase
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK

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Crispr_ID: CP022906_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022906_8

1151803-1151989

Orphan

Consensus_repeat	Method
GGCGGGGCCCCAACATAGA	CRT

3 spacers

The CRISPR arrays of CP022906_8

>merge|CP022906|8|1151803-1151989|CRT
GGCGGGGCCCCAACATAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGTGGGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGTGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACATAGA

>CP022906|8|2|1151803-1151989|CRT
GGCGGGGCCCCAACATAGA	GAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTG
GGGTGGGCCCCAACACAGA	AGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTT
GGCGGGGCCCCAACATAGT	GAAATTGGATTCCCAATTTCTACAGACAATGCAAGTT
GGCGGGGCCCCAACATAGA

Protein	Signature genes	Signature genes Name	Protein_function
CP022906.1\|AXJ80553.1\|1157138_1158695_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224207
CP022906.1\|AXJ80556.1\|1160730_1160919_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225382
CP022906.1\|AXJ80542.1\|1146998_1147349_+\|Complement-inhibitor-precursor	unknown	unknown	gnl\|CDD\|371594
CP022906.1\|AXJ80539.1\|1144509_1144911_-\|FPRL1-inhibitory-protein-precursor	unknown	unknown	gnl\|CDD\|171849
CP022906.1\|AXJ80543.1\|1148170_1148356_-\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ80554.1\|1159002_1159230_+\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ80552.1\|1156031_1156967_+\|Carbamate-kinase-1	unknown	unknown	gnl\|CDD\|237071
CP022906.1\|AXJ80538.1\|1143811_1144141_+\|Fibrinogen-binding-protein-precursor	unknown	unknown	gnl\|CDD\|289007
CP022906.1\|AXJ80547.1\|1151449_1151647_+\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ80540.1\|1145582_1146089_+\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ80548.1\|1152203_1152920_-\|superantigen-like-protein	unknown	unknown	gnl\|CDD\|171995
CP022906.1\|AXJ80541.1\|1146347_1146845_+\|Fibrinogen-binding-protein-precursor	unknown	unknown	gnl\|CDD\|289007
CP022906.1\|AXJ80550.1\|1153847_1154573_-\|superantigen-like-protein	unknown	unknown	gnl\|CDD\|171855
CP022906.1\|AXJ80549.1\|1153027_1153753_-\|Exotoxin-type-H-precursor	unknown	unknown	gnl\|CDD\|106307
CP022906.1\|AXJ80545.1\|1149687_1150647_-\|Alpha-hemolysin-precursor	unknown	unknown	gnl\|CDD\|273388
CP022906.1\|AXJ80555.1\|1159534_1160482_-\|C4-dicarboxylate-transporter/malic-acid-transport-protein	unknown	unknown	gnl\|CDD\|187765
CP022906.1\|AXJ80551.1\|1155010_1156012_+\|Ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269
CP022906.1\|AXJ80557.1\|1161830_1161965_+\|Antibacterial-protein-3	unknown	unknown	gnl\|CDD\|368464
CP022906.1\|AXJ80544.1\|1148977_1149211_-\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ80546.1\|1151319_1151466_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP022906.1\|AXJ80553.1\|1157138_1158695_+\|hypothetical-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	0
CP022906.1\|AXJ80556.1\|1160730_1160919_+\|hypothetical-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	0.00787195
CP022906.1\|AXJ80542.1\|1146998_1147349_+\|Complement-inhibitor-precursor	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	2.0882e-48
CP022906.1\|AXJ80539.1\|1144509_1144911_-\|FPRL1-inhibitory-protein-precursor	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	1.2905e-75
CP022906.1\|AXJ80552.1\|1156031_1156967_+\|Carbamate-kinase-1	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
CP022906.1\|AXJ80538.1\|1143811_1144141_+\|Fibrinogen-binding-protein-precursor	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	4.63429e-22
CP022906.1\|AXJ80555.1\|1159534_1160482_-\|C4-dicarboxylate-transporter/malic-acid-transport-protein	gnl\|CDD\|187765	cd09325, TDT_C4-dicarb_trans, C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.	7.44089e-84
CP022906.1\|AXJ80551.1\|1155010_1156012_+\|Ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0
CP022906.1\|AXJ80541.1\|1146347_1146845_+\|Fibrinogen-binding-protein-precursor	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	5.40265e-27
CP022906.1\|AXJ80550.1\|1153847_1154573_-\|superantigen-like-protein	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	8.18566e-161
CP022906.1\|AXJ80545.1\|1149687_1150647_-\|Alpha-hemolysin-precursor	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	4.27434e-141
CP022906.1\|AXJ80548.1\|1152203_1152920_-\|superantigen-like-protein	gnl\|CDD\|171995	PRK13350, PRK13350, superantigen-like protein; Reviewed.	1.29441e-152
CP022906.1\|AXJ80557.1\|1161830_1161965_+\|Antibacterial-protein-3	gnl\|CDD\|368464	pfam05480, Staph_haemo, Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.	6.35158e-13
CP022906.1\|AXJ80549.1\|1153027_1153753_-\|Exotoxin-type-H-precursor	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	1.29834e-148

>CP022906.1|AXJ80547.1|1151449_1151647_+|hypothetical-protein
MTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>CP022906.1|AXJ80546.1|1151319_1151466_+|hypothetical-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>CP022906.1|AXJ80545.1|1149687_1150647_-|Alpha-hemolysin-precursor
MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWIDRSSERYKIDWEKEEMTN
>CP022906.1|AXJ80544.1|1148977_1149211_-|hypothetical-protein
MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>CP022906.1|AXJ80543.1|1148170_1148356_-|hypothetical-protein
MNKHINKKAAKLLEDYKKVQQRKSKETDRGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>CP022906.1|AXJ80542.1|1146998_1147349_+|Complement-inhibitor-precursor
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
>CP022906.1|AXJ80541.1|1146347_1146845_+|Fibrinogen-binding-protein-precursor
MKNKLIAKSLLTLAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK
>CP022906.1|AXJ80540.1|1145582_1146089_+|hypothetical-protein
MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYISLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVVLEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIFNYRMRSYK
>CP022906.1|AXJ80539.1|1144509_1144911_-|FPRL1-inhibitory-protein-precursor
MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDDGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY
>CP022906.1|AXJ80538.1|1143811_1144141_+|Fibrinogen-binding-protein-precursor
MKKNFIGKSILSIAAISLTVSTFAGESHAQTKNVEAAKKYDQYQTNFKKQVNKKVVDAQKAVNFFKRTRTVATHRKAQRAVNLIHFQHSYEKKKLQRQIDLVLKYNTLK
>CP022906.1|AXJ80548.1|1152203_1152920_-|superantigen-like-protein
MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYNENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD
>CP022906.1|AXJ80549.1|1153027_1153753_-|Exotoxin-type-H-precursor
MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>CP022906.1|AXJ80550.1|1153847_1154573_-|superantigen-like-protein
MKKNIMNKLVLSTALLLLETTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPRNAEIEVILEKSN
>CP022906.1|AXJ80551.1|1155010_1156012_+|Ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEIMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
>CP022906.1|AXJ80552.1|1156031_1156967_+|Carbamate-kinase-1
MMAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
>CP022906.1|AXJ80553.1|1157138_1158695_+|hypothetical-protein
MENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS
>CP022906.1|AXJ80554.1|1159002_1159230_+|hypothetical-protein
MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGVPSEMIKDRQRKNNGV
>CP022906.1|AXJ80555.1|1159534_1160482_-|C4-dicarboxylate-transporter/malic-acid-transport-protein
MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLENVYPSWTVLFIGIAIAGLTAPVSGYFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLLLAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFFLKKEKQDKFLRNASQ
>CP022906.1|AXJ80556.1|1160730_1160919_+|hypothetical-protein
MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKNERSLDNMSLKNAELLYKFANSIFSNEN
>CP022906.1|AXJ80557.1|1161830_1161965_+|Antibacterial-protein-3
MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF

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Crispr_ID: CP022906_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022906_9

1857026-1857252

Orphan

Consensus_repeat	Method
GGGCCCCAACACAGAAGCTGGCCAATAGTCAGCTTTCAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022906_9

>merge|CP022906|9|1857026-1857252|CRISPRCasFinder
GGGCCCCAACATAGAAGCTGGCCAATAGTTAGCTTTCAATAATGTGCAAGTTGGGGTAAGGGCCCCAACACAGAAGCTGGCCAATAGTCAGCTTTCAATAATGTGCAAGTTGGGGTAAGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGCCAATAGTCAGCTTTCAATAATGTGCAAGTTGG

>CP022906|9|7|1857026-1857252|CRISPRCasFinder
GGGCCCCAACATAGAAGCTGGCCAATAGTTAGCTTTCAATAATGTGCAAGTTGG	GGTAAGGGCCCCAACACAGAAGCTGGCCAATAGTCAGCTTTCAATAATGTGCAAGTTGGGGTAAGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGACAATGCAAGTTGGCG
GGGCCCCAACACAGAAGCTGGCCAATAGTCAGCTTTCAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
CP022906.1\|AXJ81188.1\|1858762_1860424_-\|putative-cell-division-protein-YtgP	unknown	unknown	gnl\|CDD\|240529
CP022906.1\|AXJ81191.1\|1869101_1869413_-\|molybdopterin-biosynthesis-like-protein-MoeZ	unknown	unknown	gnl\|CDD\|238089
CP022906.1\|AXJ81194.1\|1873430_1874384_+\|coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|224163
CP022906.1\|AXJ81181.1\|1851137_1851980_-\|putative-quorum-quenching-lactonase-YtnP	unknown	unknown	gnl\|CDD\|293814
CP022906.1\|AXJ81179.1\|1849538_1850615_-\|Glutamyl-aminopeptidase	unknown	unknown	gnl\|CDD\|349906
CP022906.1\|AXJ81193.1\|1872139_1873321_-\|Multidrug-resistance-protein-MdtH	unknown	unknown	gnl\|CDD\|340887
CP022906.1\|AXJ81182.1\|1852449_1853094_-\|tRNA-(guanine-N(7)-)-methyltransferase	unknown	unknown	gnl\|CDD\|234649
CP022906.1\|AXJ81177.1\|1848205_1849063_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237463
CP022906.1\|AXJ81180.1\|1850698_1851013_+\|Peptidase-propeptide-and-YPEB-domain-protein	unknown	unknown	gnl\|CDD\|227871
CP022906.1\|AXJ81189.1\|1860830_1862099_+\|tricarballylate-dehydrogenase	unknown	unknown	gnl\|CDD\|367519
CP022906.1\|AXJ81185.1\|1855302_1856712_-\|Putative-dipeptidase	unknown	unknown	gnl\|CDD\|235988
CP022906.1\|AXJ81176.1\|1847580_1848177_-\|Phenylalanine--tRNA-ligase-beta-subunit	unknown	unknown	gnl\|CDD\|234804
CP022906.1\|AXJ81186.1\|1857631_1858054_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378938
CP022906.1\|AXJ81183.1\|1853108_1853900_-\|Phosphotransferase-enzyme-family-protein	unknown	unknown	gnl\|CDD\|223584
CP022906.1\|AXJ81178.1\|1849162_1849474_-\|Thioredoxin-like-protein-YtpP	unknown	unknown	gnl\|CDD\|239245
CP022906.1\|AXJ81192.1\|1869434_1871852_-\|Leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
CP022906.1\|AXJ81184.1\|1854450_1855299_-\|D-alanine-aminotransferase	unknown	unknown	gnl\|CDD\|130191
CP022906.1\|AXJ81187.1\|1858070_1858766_-\|Ribosomal-small-subunit-pseudouridine-synthase-A	unknown	unknown	gnl\|CDD\|224108
CP022906.1\|AXJ81195.1\|1874380_1874944_+\|16S-rRNA-m(4)C1402-methyltransferase	unknown	unknown	gnl\|CDD\|377744
CP022906.1\|AXJ81190.1\|1862215_1868776_-\|Extracellular-matrix-binding-protein-ebh-precursor	unknown	unknown	gnl\|CDD\|275089

Protein	Function_ID	Function_description	E-value
CP022906.1\|AXJ81188.1\|1858762_1860424_-\|putative-cell-division-protein-YtgP	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.63186e-123
CP022906.1\|AXJ81191.1\|1869101_1869413_-\|molybdopterin-biosynthesis-like-protein-MoeZ	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	1.46882e-25
CP022906.1\|AXJ81194.1\|1873430_1874384_+\|coproporphyrinogen-III-oxidase	gnl\|CDD\|224163	COG1242, COG1242, Predicted Fe-S oxidoreductase [General function prediction only].	0
CP022906.1\|AXJ81181.1\|1851137_1851980_-\|putative-quorum-quenching-lactonase-YtnP	gnl\|CDD\|293814	cd07728, YtnP-like_MBL-fold, Bacillus subtilis YtnP and related proteins; MBL-fold metallo hydrolase domain. Bacillus subtilis YtnP inhibits the signaling pathway required for the streptomycin production and development of aerial mycelium in Streptomyces griseus. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.38932e-155
CP022906.1\|AXJ81179.1\|1849538_1850615_-\|Glutamyl-aminopeptidase	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	2.36515e-152
CP022906.1\|AXJ81193.1\|1872139_1873321_-\|Multidrug-resistance-protein-MdtH	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.66072e-94
CP022906.1\|AXJ81182.1\|1852449_1853094_-\|tRNA-(guanine-N(7)-)-methyltransferase	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	1.40225e-87
CP022906.1\|AXJ81177.1\|1848205_1849063_-\|hypothetical-protein	gnl\|CDD\|237463	PRK13668, PRK13668, hypothetical protein; Provisional.	2.02352e-168
CP022906.1\|AXJ81180.1\|1850698_1851013_+\|Peptidase-propeptide-and-YPEB-domain-protein	gnl\|CDD\|227871	COG5584, COG5584, Predicted small secreted protein [Function unknown].	4.19522e-46
CP022906.1\|AXJ81189.1\|1860830_1862099_+\|tricarballylate-dehydrogenase	gnl\|CDD\|367519	pfam03486, HI0933_like, HI0933-like protein.	0
CP022906.1\|AXJ81185.1\|1855302_1856712_-\|Putative-dipeptidase	gnl\|CDD\|235988	PRK07318, PRK07318, dipeptidase PepV; Reviewed.	0
CP022906.1\|AXJ81176.1\|1847580_1848177_-\|Phenylalanine--tRNA-ligase-beta-subunit	gnl\|CDD\|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	7.47641e-48
CP022906.1\|AXJ81186.1\|1857631_1858054_-\|hypothetical-protein	gnl\|CDD\|378938	pfam12732, YtxH, YtxH-like protein. This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 143 amino acids in length. The N-terminal region is the most conserved. Proteins is this family are functionally uncharacterized.	0.000542053
CP022906.1\|AXJ81183.1\|1853108_1853900_-\|Phosphotransferase-enzyme-family-protein	gnl\|CDD\|223584	COG0510, ycfN, Thiamine kinase and related kinases [Coenzyme transport and metabolism].	5.2385e-83
CP022906.1\|AXJ81178.1\|1849162_1849474_-\|Thioredoxin-like-protein-YtpP	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.34221e-24
CP022906.1\|AXJ81192.1\|1869434_1871852_-\|Leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
CP022906.1\|AXJ81184.1\|1854450_1855299_-\|D-alanine-aminotransferase	gnl\|CDD\|130191	TIGR01121, D-alanine_aminotransferase, D-amino acid aminotransferase. This enzyme is a homodimer. The pyridoxal phosphate attachment site is the Lys at position 146 of the seed alignment, in the motif Cys-Asp-Ile-Lys-Ser-Leu-Asn. Specificity is broad for various D-amino acids, and differs among members of the family; the family is designated equivalog, but with this caveat attached. [Energy metabolism, Amino acids and amines].	6.28892e-159
CP022906.1\|AXJ81187.1\|1858070_1858766_-\|Ribosomal-small-subunit-pseudouridine-synthase-A	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	2.1062e-94
CP022906.1\|AXJ81195.1\|1874380_1874944_+\|16S-rRNA-m(4)C1402-methyltransferase	gnl\|CDD\|377744	pfam06962, rRNA_methylase, Putative rRNA methylase. This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins.	2.38341e-67
CP022906.1\|AXJ81190.1\|1862215_1868776_-\|Extracellular-matrix-binding-protein-ebh-precursor	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	2.99104e-115

>CP022906.1|AXJ81185.1|1855302_1856712_-|Putative-dipeptidase
MWKEKVQQYEDQIINDLKGLLAIESVRDDAKASEDAPVGPGPRKALDYMYEIAHRDGFTTHDVDHIAGRIEAGKGNDVLGILCHVDVVPAGDGWDSNPFEPVVTEDAIIARGTLDDKGPTIAAYYAIKILEDMNVDWKKRIHMIIGTDEESDWKCTDRYFKTEEMPTLGFAPDAEFPCIHGEKGITTFDLVQNKLTEDQDEPDYELITFKSGERYNMVPDHAEARVLVKENMTDVIQDFEYFLEQNHLQGDSTVDSGILVLTVEGKAVHGMDPSIGVNAGLYLLKFLASLNLDNNAQAFVAFSNRYLFNSDFGEKMGMKFHTDVMGDVTTNIGVITYDNENAGLFGINLRYPEGFEFEKAMDRFANEIQQYGFEVKLGKVQPPHYVDKNDPFVQKLVTAYRNQTNDMTEPYTIGGGTYARNLDKGVAFGAMFSDSEDLMHQKNEYITKKQLFNATSIYLEAIYSLCVEE
>CP022906.1|AXJ81184.1|1854450_1855299_-|D-alanine-aminotransferase
MEKIFLNGEFVSPSEAKVSYNDRGYVFGDGIYEYIRVYNGKLFTVTEHYERFLRSANEIGLDLNYSVEELIELSRKLVDMNQIETGAIYIQATRGVAERNHSFPTPEVEPAIVAYTKSYDRPYDHLENGVNGVTVEDIRWLRCDIKSLNLLGNVLAKEYAVKYNAVEAIQHRGETVTEGSSSNAYAIKDGVIYTHPINNYILNGITRIVIKKIAEDYNIPFKEETFTVDFLKNADEVIVSSTSAEVTPVIKLDGEPVNDGKVGPITRQLQEGFEKYIESHSI
>CP022906.1|AXJ81183.1|1853108_1853900_-|Phosphotransferase-enzyme-family-protein
MEQFYQLGWTLDSAGGASGEAYMAEQDGQKLFLKRNSNPFIAALSAEGIVPKLVWTKRIETGEVVTAQHWKNGRELSSNEMKQTRVAHLLKKIHNSRPLLSMLKRMEMEPITPEIMLNKINASLSREVLTHHIVRKSLTYLEEHIPSLDSRFFTVVHGDVNHNNWLLSDRDELFLVDWEGAMIADPAIDIGMLLYNYVPQQQWSEWLETYGVQESLNLNKRMKWYTVIQSIGLVQWYEEQKRYKDMNTWLKFLNEVMNSNMFI
>CP022906.1|AXJ81182.1|1852449_1853094_-|tRNA-(guanine-N(7)-)-methyltransferase
MRVRYKPWAKDYLKDHPELVDMDGQHAGKMTEWFDKTQPIHIEIGSGMGQFITTLAAQNPHINYISMEREKSIVYKVLDKVKEMGLTNLKIICNDAIELNEYFKDGEVSRIYLNFSDPWPKNRHAKRRLTYHTFLALYQQILNDEGDLHFKTDNRGLFAYSLESMSQFGMYFTKINLNLHQEDDGSNILTEYEKKFSDKGSRIYRMEAKFHSQK
>CP022906.1|AXJ81181.1|1851137_1851980_-|putative-quorum-quenching-lactonase-YtnP
MKIGDISIHYLNGGNTKMDGGAMFGVVPKPLWSKQYNANERNQINLPTHPILIQTAQYNLIIDAGIGNGKLSEKQLRNFGVDEESHIIADLANYNLTPKDIDYVLMTHMHFDHAAGLTDQAGHAIFENAIHVVQQDEWHEFIAPNIRSKSTYWDKNKGDYSNKLILFEKHFEPVLGIKMQHSGGHSFGHTIITIESQGDKAVHMGDIFPTTAHKNPLWVTAYDDYPMQSIREKERMIPYFIQQQYWFLFYHDENYFAVKYSDNGENIDAYILRETLVDNN
>CP022906.1|AXJ81180.1|1850698_1851013_+|Peptidase-propeptide-and-YPEB-domain-protein
MMTKLKYIIPTIIAVAIVIISTISIIQFINRKRYNPVKVLNEVKSYFMNVKGSYIVYEPFVHPETDKYRLVYQGGITTIKNGQNIHYDFYADAYTGEVINIVER
>CP022906.1|AXJ81179.1|1849538_1850615_-|Glutamyl-aminopeptidase
MNINKKVTLQRIQTLTELHGAPGFEEEVKNYMTQQMAPYVDEFIENRMGGFFGVKKSKNPNAKRVMIAAHMDEIGFMITNITKNGMIQFTNLGGVANDIWQGQRLVIKNRNGDKIIGVVSNIPKHFRTGSEGAPEIKDLTLDIGAQNEDEVRERGIDIGDTIVPHTPFTQLSEHRYSAKAWDNRYGCVLAIEILELLKDIELDVDLYVGANVQEEVGLRGAKASAEMIDPDVAFVVDCSPANDVKGNQPLSGELGKGTLIRIKDGTMILKPVFRDYLLKLVEAHDIEHQYYMSPGGTDGGEIHKANIGIPTAVIGVCARYIHSTDSVFDIRDYFAARSLLSEAICNLDNNQIETLQYK
>CP022906.1|AXJ81178.1|1849162_1849474_-|Thioredoxin-like-protein-YtpP
MKQLESEQQFESLKQGATVFEFTAGWCPDCRVIEPDLPELEARYPMFDFVSVDRDKFMDICIENGIMGIPSFLVYKNGELLGSYIGKERKSIEQIDAFLAQYV
>CP022906.1|AXJ81177.1|1848205_1849063_-|hypothetical-protein
MNTFQMRDKLKERLSHLDVDFKFNREEETLRIYRTDNNKGITIKLNAIVAKYEDKKEKIVDEIVYYVDEAIAQMADKTLESISSSQIMPVIRATSFDKKTKQGVPFIYDEHTAETAVYYAVDLGKSYRLIDESMLEDLKLTEQQIREMSLFNVRKLSNSYTTDEVKGNIFYFINSNDGYDASRILNTAFLNEIEAQCQGEMLVAVPHQDVLIIADIRNKTGYDVMAHLTMEFFTKGLVPITSLSFGYKQGHLEPIFILGKNNKQKRDPNVIQRLEANRRKFNKDK
>CP022906.1|AXJ81176.1|1847580_1848177_-|Phenylalanine--tRNA-ligase-beta-subunit
MNLFYNPKYVGDVAFLQIEPVEGELNYNKKGNVVEITNEGNVVGYNIFEISKDITIEEKGHIKLTDELVNVFQKRISEAGFDYKLNADLSPKFVVGYVETKDKHPDADKLSVLNVNVGNDTLQIVCGAPNVEAGQKVVVAKVGAVMPSGMVIKDAELRGVASSGMICSMKELNLPNAPEEKGIMVLNDSYEIGQAFFE
>CP022906.1|AXJ81186.1|1857631_1858054_-|hypothetical-protein
MAKGNLFKAILGIGGAVAAVLVTRKDSRDKLKAEYNKYKQDPQSYKDNAKDKATQLGTIANETIKEVKTNPKEYANRLKNNPKAFFKEEKSKFTEYDNKTDESIEKGKFDDEGGAAPNNNLRIVTEEDLKKNKNALSDKE
>CP022906.1|AXJ81187.1|1858070_1858766_-|Ribosomal-small-subunit-pseudouridine-synthase-A
MRIDKFLANMGVGTRNEVKQLLKKGLVNVNEQVIKSPKTHIEPENDKITVRGELIEYIENVYIMLNKPKGYISATEDHHSKTVIDLIPEYQHLNIFPVGRLDKDTEGLLLITNDGDFNHELMSPNKHVSKKYEVISANPITEDDIQAFKEGVTLTDGKVKPAILTYIDNQTSHVTIYEGKYHQVKRMFHSIQNEVLHLRRIKIADLELDSNLDSGEYRLLTENDFDKLNYK
>CP022906.1|AXJ81188.1|1858762_1860424_-|putative-cell-division-protein-YtgP
MSESKEMVRGTFLITISILITKVLGVLFIIPFNYLIGGQENMAPFTYAYAPYNIAIAVATAGVPLAASKYVAKYNAIGAYKVSQKFYKSSFIVMSITGVLGFLVLYFLAPYISELTLARNIHDKNGWSVDDITWIIRIISMVVIFIPVLATWRGIFQGYKSMGPTAVSEVTEQIARVIFILIGSYLVLNVFDGSILLANGIATFAAAVGAIIGIFTLWYYWRKRKHNIDRMVESDYTDIDVSYGKMYKEIIAYSIPFVIVSLNYPLFNLVDQFTHNGALSLVGIPSQLQDIFFNMLNMSTNKIVMIPTSLSAGFAVSLIPYITKTFAEGRLHEMHHQIRTSIGVLMFITVPASIGIMALAQPLFTVFYGYDPIVLGHDPNHDGSRLLFYYAPVAILISLLSVTASMLQGIDKQKLTVYVILASVVIKLALNYPLIMLFHTPGAILSTSIALLFAIGCNFYILKKYAKFKFSYSWIHFAKIFLYSFIMMLGVELVFFLANLFLEPTKLGYLIIIILGVTVGILIYGTITIKTRLADEFLGEIPEKLRRRVRFLR
>CP022906.1|AXJ81189.1|1860830_1862099_+|tricarballylate-dehydrogenase
MYQTIIIGGGPSGLMAAVAASEQSSSVLLIEKKKGLGRKLKISGGGRCNVTNRLPYAEIIKNIPGNGKFLYSPFSIFDNESIIDFFESRGVKLKEEDHGRMFPVSNKAQDVVDTLVTTIERQHVTIKEEEAVSRIEVNTDQTFTVHTQNNSYESHSLVIATGGTSVPQTGSTGDGYKFAQDLGHTITELFPTEVPITSAEPFIKSNRLKGLSLKDVELSVLKKNGKKRISHQMDMLFTHFGISGPAALRCSQFVYKEQKNQKTQHISMAIDAFPELNHEQLKQHITSLLSDTPDKIIKNSLHGLIEERYLLFMLEQAGIDENTTSHHLSNQQLNDLVNMFKGFVFKVNGTLPIDKAFVTGGGVSLKEIQPKTMMSKLVPGLFLCGEVLDIHGYTGGYNITSALVTGHVAGLYAGHYSHASME
>CP022906.1|AXJ81190.1|1862215_1868776_-|Extracellular-matrix-binding-protein-ebh-precursor
MNLLKKNKYSIRKYKVGIFSTLIGTVLLLSNPNGAQALTTDNNVQSDTNQATPVNSQDKDVANNRGLANSAQNTPNQSATTNQATNQALVNHNNGSIVNQATPTSVQSSTPSAQNNNHTDGNTTATETVSNANNNDVVSNNTALNVPTKTNENGSGGHLTLKEIQEDVRHSSNKPELVAIAEPASNRPKKRSRRAAPADPNATPADPAAAAVGNGGAPVAITAPYTPTTDPNANNAGQNAPNEVLSFDDNGIRPSTNRSVPTVNVVNNLPGFTLINGGKVGVFSHAMVRTSMFDSGDNKNYQAQGNVIALGRIHGTDTNDHGDFNGIEKALTVNPNSELIFEFNTMTTKNGQGATNVIIKNADTNDTIAEKTVEGGPTLRLFKVPDNVRNLKIQFVPKNDAITDARGIYQLKDGYKYYSFVDSIGLHSGSHVFVERRTMDPTATNNKEFTVTTSLKNNGNSGASLDTNDFVYQVQLPEGVEYVNNSLTKDFPSNNSGVDVNDMNVTYDAANRVITIKSTGGGTANSPARLMPDKILDLRYKLRVNNVPTPRTVTFNETLTYKTYTQDFINSAAESHTVSTNPYTIDIIMNKDALQAEVDRRIQQADYTFASLDIFNGLKRRAQTILDENRNNVPLNKRVSQAYIDSLTNQMQHTLIRSVDAENAVNKKVDQMEDLVNQNDELTDEEKQAAIQVIEEHKNEIIGNIGDQTTDDGVTRIKDQGIQTLSGDTATPVVKPNAKKAIRDKATKQREIINATPDVTEDEIQDALNQLATDETDAIDNVTNATTNADVETAKNNGINTIGAVVPQVTHKKAARDAINQATATKRQQINSNREATQEEKNAALNELTQATNHALEQINQATTNADVDNAKGDGLNAINPIAPVTVVKQAARDAVSHDAQQHIAEINANPDATQEERQAAIDKVNAAVTAANTNILNANTNADVEQVKTNAIQGIQAITPATKVKTDAKNAIDKSAETQHNTIFNNNDATLEEQQAAQQLLDQAVATAKQNINAADTNQEVAQAKDQGTQNIVVIQPATQVKTDTRNVVNDKAREAITNINATTGATREEKQEAINRVNTLKNRALTDIGVTSTTAMVNSIRDDAVNQIGAVQPHVTKKQTATGVLNDLATAKKQEINQNTNATTEEKQVALNQVDQELATAINNINQADTNAEVDQAQQLGTKAINAIQPNIVKKPAALAQINQHYNAKLAEINATPDATNDEKNAAINTLNQDRQQAIESIKQANTNAEVDQAATVAENNIDAVQVDVVKKQAARDKITAEVAKRIEAVKQTPNATDEEKQAAVNQINQLKDQAINQINQNQTNDQVDTTTNQAVNAIDNVEAEVVIKPKAIADIEKAVKEKQQQIDNSLDSTDNEKEVASQALAKEKEKALAAIDQAQTNSQVNQAATNGVSAIKIIQPETKVKPAAREKINQKANELRAKINQDKEATAEERQVALDKINEFVNQAMTDITNNRTNQQVDDTTSQALDSIALVTPDHIVRAAARDAVKQQYEAKKREIEQAEHATDEEKQVALNQLANNEKRALQNIDQAIANNDVKRVETNGIATLKGVQPHIVIKPEAQQAIKASAENQVESIKDTPHATVDELDEANQLISDTLKQAQQEIENTNQDAAVTDVRNQTIKAIEQIKPKVRRKRAALDSIEENNKNQLDAIRNTLDTTQDERDVAIDTLNKIVNTIKNDIAQNKTNAEVDRTETDGNDNIKVILPKVQVKPAARQSVGVKAEAQNALIDQSDLSTEEERLAAKHLVEQALNQAIDQINHADKTAQVNQDSINAQNIISKIKPATTVKATALQQIQNIATNKINLIKANNEATDEEQNIAIAQVEKELIKAKQQIASAVTNADVAYLLHDEKNEIREIEPVINRKASAREQLTTLFNDKKQAIEANIQATVEERNSILAQLQNIYDTAIGQIDQDRSNAQVDKTASLNLQTIHDLDVHPIKKPDAEKTINDDLARVTALVQNYRKVSNRNKADALKAITALKLQMDEELKTARTNADVDAVLKRFNVALSDIEAVITEKENSLLRIDNIAQQTYAKFKAIATPEQLAKVKVLIDQYVADGNRMIDEDATLNDIKQHTQFIVDEILAIKLPAEATKVSPKEIQPAPKVCTPIKKEETHESRKVEKELPNTGSEGMDLPLKEFALITGAALLARRRTKNEKES
>CP022906.1|AXJ81191.1|1869101_1869413_-|molybdopterin-biosynthesis-like-protein-MoeZ
MKSITTDELKNKLLESKPVQIVDVRTDEETAMGYIPNAKLIPMDTIPDNLNSFNKNEIYYIVCAGGVRSAKVVEYLEANGIDAVNVEGGMHAWGDEGLEIKSI
>CP022906.1|AXJ81192.1|1869434_1871852_-|Leucine--tRNA-ligase
MLNYNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVIDGVSERGGHPVYRKPMKQWVLKITEYADQLLADLDDLDWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKSGVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPIIEVIEGGNVEEAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQRYWGEPIPVIHWEDGTMTTVPEEELPLLLPETDEIKPSGTGESPLANIDSFVNVVDEKTGMKGRREINTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLAIVPTKEPFQKLFNQGMILGEGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKLGHEESITYQPWPTYDEALLVDDEVEIVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK
>CP022906.1|AXJ81193.1|1872139_1873321_-|Multidrug-resistance-protein-MdtH
MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAGLVLMINSFGMVIGNLLGGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLVMLGFGGGMIIPAIYAMAGAVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYIFLANLIMYVVFALVAVTQFNIEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICWVAYIQWESTIASFTQSINISMAQYSVLWTINGIMILVAQPLIKPILYLLKGNLKKQMFVGIIIFMLSFFVTSFAENFTIFVVGMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQGFVNSAATVGKAFGPFLGGVLVDAFNMRMMFIGMMLLLVFALILLMVFKENNTQPKKIDA
>CP022906.1|AXJ81194.1|1873430_1874384_+|coproporphyrinogen-III-oxidase
MGNHFQYAFENKRYHTWNYHLKNKFGQKIFKVALDGGFDCPNRDGTVAHGGCTFCSAAGSGDFAGNRADSIAVQFKEIKEKMHEKWHEGKYIAYFQAFTNTHAPVEVLKEKFEPVLKEPGVVGLSIGTRPDCLPDDVVEYLADLNQRTYLWVELGLQTIHQSTSDLINRAHDMKTYYDGVAKLRKHNINVCTHIINGLPGEDYDMMMATAKEVAQMDVQGIKIHLLHLLKGTPMVKQYDKGLLTFMTQEEYTNLVVDQLEVIPPEMIVHRITGDGPIDIMVGPMWSVNKWEVLNGIDAELARRNSYQGLRYKSKVKQ
>CP022906.1|AXJ81195.1|1874380_1874944_+|16S-rRNA-m(4)C1402-methyltransferase
MKLERILPFSKTLIKQHITPESIVVDATCGNGNDTLFLAEQVPEGHVYGFDIQDLALENTRDKVKDFNHVSLIKDGHENIEHHINDAHKGHIDAAIFNLGYLPKGDKSIVTKPDTTIQAINSLLSLMSIEGIIVLVIYHGHSEGQIEKHALLDYLSTLDQKHAQVLQYQFLNQRNHAPFICAIEKIS

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Crispr_ID: CP022906_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022906_10

2062346-2062424

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACCTGCA	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of CP022906_10

>merge|CP022906|10|2062346-2062424|CRISPRCasFinder
TGTTGGGGCCCCGCCAACCTGCACATTATCGTAAGCTGACTTTTCGTCAGCTTCTGTGTTGGGGCCCCGCCAACCTGCA

>CP022906|10|8|2062346-2062424|CRISPRCasFinder
TGTTGGGGCCCCGCCAACCTGCA	CATTATCGTAAGCTGACTTTTCGTCAGCTTCTG
TGTTGGGGCCCCGCCAACCTGCA

Protein	Signature genes	Signature genes Name	Protein_function
CP022906.1\|AXJ81388.1\|2064745_2065477_-\|cobyric-acid-synthase	unknown	unknown	gnl\|CDD\|225974
CP022906.1\|AXJ81394.1\|2070611_2071973_-\|putative-RNA-methyltransferase	unknown	unknown	gnl\|CDD\|225174
CP022906.1\|AXJ81378.1\|2056069_2056534_+\|Low-molecular-weight-protein-tyrosine-phosphatase-PtpA	unknown	unknown	gnl\|CDD\|319971
CP022906.1\|AXJ81382.1\|2059045_2060089_-\|Sensor-protein-VraS	unknown	unknown	gnl\|CDD\|226951
CP022906.1\|AXJ81390.1\|2067083_2067584_+\|Ferritin	unknown	unknown	gnl\|CDD\|224445
CP022906.1\|AXJ81395.1\|2072053_2073001_-\|Diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|183982
CP022906.1\|AXJ81384.1\|2060801_2061188_-\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ81386.1\|2062690_2063677_+\|Fusaric-acid-resistance-protein-family-protein	unknown	unknown	gnl\|CDD\|226614
CP022906.1\|AXJ81379.1\|2056540_2056816_+\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ81387.1\|2064107_2064521_-\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ81393.1\|2069911_2070442_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378690
CP022906.1\|AXJ81376.1\|2054463_2055711_-\|Aminopeptidase-PepS	unknown	unknown	gnl\|CDD\|376723
CP022906.1\|AXJ81381.1\|2058426_2059056_-\|Response-regulator-protein-VraR	unknown	unknown	gnl\|CDD\|225107
CP022906.1\|AXJ81377.1\|2055722_2055929_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227177
CP022906.1\|AXJ81389.1\|2065478_2066792_-\|UDP-N-acetylmuramate--L-alanine-ligase	unknown	unknown	gnl\|CDD\|223840
CP022906.1\|AXJ81383.1\|2060085_2060787_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227100
CP022906.1\|AXJ81391.1\|2067972_2068527_+\|DNA-polymerase-III-PolC-type	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
CP022906.1\|AXJ81392.1\|2068594_2069665_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
CP022906.1\|AXJ81385.1\|2061404_2062163_-\|Methionine-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
CP022906.1\|AXJ81380.1\|2057093_2058311_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224214

Protein	Function_ID	Function_description	E-value
CP022906.1\|AXJ81388.1\|2064745_2065477_-\|cobyric-acid-synthase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	3.33663e-121
CP022906.1\|AXJ81394.1\|2070611_2071973_-\|putative-RNA-methyltransferase	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	0
CP022906.1\|AXJ81378.1\|2056069_2056534_+\|Low-molecular-weight-protein-tyrosine-phosphatase-PtpA	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
CP022906.1\|AXJ81382.1\|2059045_2060089_-\|Sensor-protein-VraS	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
CP022906.1\|AXJ81390.1\|2067083_2067584_+\|Ferritin	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
CP022906.1\|AXJ81395.1\|2072053_2073001_-\|Diacylglycerol-kinase	gnl\|CDD\|183982	PRK13337, PRK13337, putative lipid kinase; Reviewed.	0
CP022906.1\|AXJ81380.1\|2057093_2058311_+\|hypothetical-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	4.24482e-85
CP022906.1\|AXJ81386.1\|2062690_2063677_+\|Fusaric-acid-resistance-protein-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.20478e-76
CP022906.1\|AXJ81393.1\|2069911_2070442_-\|hypothetical-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.4991e-11
CP022906.1\|AXJ81376.1\|2054463_2055711_-\|Aminopeptidase-PepS	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
CP022906.1\|AXJ81381.1\|2058426_2059056_-\|Response-regulator-protein-VraR	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.91794e-79
CP022906.1\|AXJ81377.1\|2055722_2055929_-\|hypothetical-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	2.64328e-25
CP022906.1\|AXJ81389.1\|2065478_2066792_-\|UDP-N-acetylmuramate--L-alanine-ligase	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	7.18737e-99
CP022906.1\|AXJ81383.1\|2060085_2060787_-\|hypothetical-protein	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
CP022906.1\|AXJ81391.1\|2067972_2068527_+\|DNA-polymerase-III-PolC-type	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	1.92778e-75
CP022906.1\|AXJ81392.1\|2068594_2069665_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
CP022906.1\|AXJ81385.1\|2061404_2062163_-\|Methionine-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126

>CP022906.1|AXJ81385.1|2061404_2062163_-|Methionine-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>CP022906.1|AXJ81384.1|2060801_2061188_-|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>CP022906.1|AXJ81383.1|2060085_2060787_-|hypothetical-protein
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>CP022906.1|AXJ81382.1|2059045_2060089_-|Sensor-protein-VraS
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>CP022906.1|AXJ81381.1|2058426_2059056_-|Response-regulator-protein-VraR
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>CP022906.1|AXJ81380.1|2057093_2058311_+|hypothetical-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIIFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>CP022906.1|AXJ81379.1|2056540_2056816_+|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>CP022906.1|AXJ81378.1|2056069_2056534_+|Low-molecular-weight-protein-tyrosine-phosphatase-PtpA
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>CP022906.1|AXJ81377.1|2055722_2055929_-|hypothetical-protein
MAMTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHE
>CP022906.1|AXJ81376.1|2054463_2055711_-|Aminopeptidase-PepS
MTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHEIKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAGKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF
>CP022906.1|AXJ81386.1|2062690_2063677_+|Fusaric-acid-resistance-protein-family-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>CP022906.1|AXJ81387.1|2064107_2064521_-|hypothetical-protein
MKPTKVILKDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEVKFEFALFDSDMDNLKHMDCDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVAKSDFTKFINELASLH
>CP022906.1|AXJ81388.1|2064745_2065477_-|cobyric-acid-synthase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
>CP022906.1|AXJ81389.1|2065478_2066792_-|UDP-N-acetylmuramate--L-alanine-ligase
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLYLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>CP022906.1|AXJ81390.1|2067083_2067584_+|Ferritin
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>CP022906.1|AXJ81391.1|2067972_2068527_+|DNA-polymerase-III-PolC-type
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKIHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>CP022906.1|AXJ81392.1|2068594_2069665_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>CP022906.1|AXJ81393.1|2069911_2070442_-|hypothetical-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ
>CP022906.1|AXJ81394.1|2070611_2071973_-|putative-RNA-methyltransferase
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVTSIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGTIGLYMAPLAKHVYGVEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
>CP022906.1|AXJ81395.1|2072053_2073001_-|Diacylglycerol-kinase
MRKRARIIYNPTSGKELFKRELPDALIKLEKAGYETSAYATEKIGDATLEAERAMHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPFAYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGYFTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGGKLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE

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Crispr_ID: CP022906_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022906_11

2257161-2257241

Orphan

Consensus_repeat	Method
TTACAACTTTAGTTGTTAGGGGCT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of CP022906_11

>merge|CP022906|11|2257161-2257241|CRISPRCasFinder
TTACAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTAAACTTTAGTTGTTAGGGGCT

>CP022906|11|9|2257161-2257241|CRISPRCasFinder
TTACAACTTTAGTTGTTAGGGGCT	CTTATGCATGCGCTTAGCGCAGGCGCTCCTACT
TTTAAACTTTAGTTGTTAGGGGCT

Protein	Signature genes	Signature genes Name	Protein_function
CP022906.1\|AXJ81560.1\|2252036_2252267_-\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ81557.1\|2248477_2248921_-\|General-stress-protein-20U	unknown	unknown	gnl\|CDD\|223854
CP022906.1\|AXJ81569.1\|2261517_2262300_-\|putative-ABC-transporter-ATP-binding-protein-YlmA	unknown	unknown	gnl\|CDD\|224044
CP022906.1\|AXJ81564.1\|2254809_2255790_+\|Cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter	unknown	unknown	gnl\|CDD\|224151
CP022906.1\|AXJ81572.1\|2266590_2268723_+\|Transcriptional-regulator-MtlR	unknown	unknown	gnl\|CDD\|226234
CP022906.1\|AXJ81566.1\|2258109_2258313_-\|DNA-invertase-hin	unknown	unknown	gnl\|CDD\|239737
CP022906.1\|AXJ81561.1\|2252297_2253236_-\|putative-mannose-6-phosphate-isomerase-GmuF	unknown	unknown	gnl\|CDD\|224399
CP022906.1\|AXJ81573.1\|2268734_2269169_+\|Mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014
CP022906.1\|AXJ81556.1\|2247646_2248357_+\|Purine-nucleoside-phosphorylase-DeoD-type-1	unknown	unknown	gnl\|CDD\|180275
CP022906.1\|AXJ81562.1\|2253670_2254336_-\|putative-sugar-epimerase-YhfK	unknown	unknown	gnl\|CDD\|187554
CP022906.1\|AXJ81570.1\|2262531_2264337_-\|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]	unknown	unknown	gnl\|CDD\|234729
CP022906.1\|AXJ81574.1\|2269168_2270275_+\|Mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
CP022906.1\|AXJ81568.1\|2260592_2261450_-\|Putative-phosphatase-YwpJ	unknown	unknown	gnl\|CDD\|223635
CP022906.1\|AXJ81567.1\|2258371_2259508_-\|SAP-domain-protein	unknown	unknown	gnl\|CDD\|366887
CP022906.1\|AXJ81558.1\|2249120_2249534_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225556
CP022906.1\|AXJ81565.1\|2256055_2257147_+\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ81559.1\|2249991_2251365_-\|EVE-domain-protein	unknown	unknown	gnl\|CDD\|376640
CP022906.1\|AXJ81575.1\|2270593_2278030_-\|Extracellular-matrix-binding-protein-ebh-precursor	unknown	unknown	gnl\|CDD\|275089
CP022906.1\|AXJ81563.1\|2254487_2254808_+\|HTH-type-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
CP022906.1\|AXJ81571.1\|2265017_2266556_+\|PTS-system-mannitol-specific-EIICB-component	unknown	unknown	gnl\|CDD\|225123

Protein	Function_ID	Function_description	E-value
CP022906.1\|AXJ81566.1\|2258109_2258313_-\|DNA-invertase-hin	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	1.78732e-14
CP022906.1\|AXJ81557.1\|2248477_2248921_-\|General-stress-protein-20U	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
CP022906.1\|AXJ81569.1\|2261517_2262300_-\|putative-ABC-transporter-ATP-binding-protein-YlmA	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	9.86955e-104
CP022906.1\|AXJ81564.1\|2254809_2255790_+\|Cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.049e-108
CP022906.1\|AXJ81572.1\|2266590_2268723_+\|Transcriptional-regulator-MtlR	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.09729e-67
CP022906.1\|AXJ81561.1\|2252297_2253236_-\|putative-mannose-6-phosphate-isomerase-GmuF	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
CP022906.1\|AXJ81573.1\|2268734_2269169_+\|Mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
CP022906.1\|AXJ81556.1\|2247646_2248357_+\|Purine-nucleoside-phosphorylase-DeoD-type-1	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
CP022906.1\|AXJ81562.1\|2253670_2254336_-\|putative-sugar-epimerase-YhfK	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.74381e-48
CP022906.1\|AXJ81570.1\|2262531_2264337_-\|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP022906.1\|AXJ81574.1\|2269168_2270275_+\|Mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
CP022906.1\|AXJ81567.1\|2258371_2259508_-\|SAP-domain-protein	gnl\|CDD\|366887	pfam02037, SAP, SAP domain. The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.	3.90307e-06
CP022906.1\|AXJ81558.1\|2249120_2249534_-\|hypothetical-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
CP022906.1\|AXJ81568.1\|2260592_2261450_-\|Putative-phosphatase-YwpJ	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	5.39747e-59
CP022906.1\|AXJ81559.1\|2249991_2251365_-\|EVE-domain-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.81104e-06
CP022906.1\|AXJ81575.1\|2270593_2278030_-\|Extracellular-matrix-binding-protein-ebh-precursor	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	6.00122e-109
CP022906.1\|AXJ81563.1\|2254487_2254808_+\|HTH-type-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
CP022906.1\|AXJ81571.1\|2265017_2266556_+\|PTS-system-mannitol-specific-EIICB-component	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0

>CP022906.1|AXJ81565.1|2256055_2257147_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEYNQPK
>CP022906.1|AXJ81564.1|2254809_2255790_+|Cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>CP022906.1|AXJ81563.1|2254487_2254808_+|HTH-type-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>CP022906.1|AXJ81562.1|2253670_2254336_-|putative-sugar-epimerase-YhfK
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGDQDIKDALTQFENETD
>CP022906.1|AXJ81561.1|2252297_2253236_-|putative-mannose-6-phosphate-isomerase-GmuF
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>CP022906.1|AXJ81560.1|2252036_2252267_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>CP022906.1|AXJ81559.1|2249991_2251365_-|EVE-domain-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTTLFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRISNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>CP022906.1|AXJ81558.1|2249120_2249534_-|hypothetical-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>CP022906.1|AXJ81557.1|2248477_2248921_-|General-stress-protein-20U
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>CP022906.1|AXJ81556.1|2247646_2248357_+|Purine-nucleoside-phosphorylase-DeoD-type-1
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>CP022906.1|AXJ81566.1|2258109_2258313_-|DNA-invertase-hin
MIVYQRKINIDTLKEFGCGCVYSERISGVKRTELVKCLDYLRESDTLVVYQLDRLGRTTKLLIELSQ
>CP022906.1|AXJ81567.1|2258371_2259508_-|SAP-domain-protein
MSVNARDLLVLHTNVNRLVGEEIFANKCLANNDVQIMNSIKKLIEAELLTTTNDFEVSIYKKTRPELQSILKSFGIKTTGNKPDLIKRIDDNFHIINNLDLPYVYIPTKKGEEILKKTEYLTSFIQSYGEISLERAYYLVENYIDENCDDKVAEIYKFEFQRKYDNGEFDFNHGYNFELNMLIDHYKRDVKDYDNARKYSNIYLYFGLRDFLKKLMSNYSYYDSKGNIDLNEIQNDLNRFINSSASGMYERLIYNENLSNNIMFELFKKDTQDYSDLEEQLIEKFINYAVSNVKKESRSNTLIELSKILENGYTIDKEEFKKEDDYLSKYIFTDIDYLKKLESKINVAIDIRSGEIHLVLDDDSLDILIQNQKYGNEF
>CP022906.1|AXJ81568.1|2260592_2261450_-|Putative-phosphatase-YwpJ
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAEHFLAE
>CP022906.1|AXJ81569.1|2261517_2262300_-|putative-ABC-transporter-ATP-binding-protein-YlmA
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEIRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITANFSKILLLKDGQSIQQGAVEDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>CP022906.1|AXJ81570.1|2262531_2264337_-|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>CP022906.1|AXJ81571.1|2265017_2266556_+|PTS-system-mannitol-specific-EIICB-component
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>CP022906.1|AXJ81572.1|2266590_2268723_+|Transcriptional-regulator-MtlR
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFISDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>CP022906.1|AXJ81573.1|2268734_2269169_+|Mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>CP022906.1|AXJ81574.1|2269168_2270275_+|Mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVLAETSQYITNEFDFTEAEQAAYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>CP022906.1|AXJ81575.1|2270593_2278030_-|Extracellular-matrix-binding-protein-ebh-precursor
MNLFRQQKFSIRKFNVGIFSALIATVTFISTNPTTASAAEQNQPAQNQPAQPADANTQPNANAGAQANPTAQPAAPANQGQPAVQPANQGGQANPAGGAAQPNTQPAGQGNQADPNNAAQAQPGNQATPANQAGQGNNQATPNNNATPANQTQPANAPAAAQPAAPVAANAQTQDPNASNTGEGSINTTLTFDDPAISTDENRQDPTVTVTDKVNGYSLINNGKIGFVNSELRRSDMFDKNNPQNYQAKGNVAALGRVNANDSTDHGNFNGISKTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLDLQFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGASLKADQFKYEVTLPQGVTYVNNSLTTTFPNGNEDSTVLKNMTVNYDQNANKVTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNVANIDTPKNIDFNEKLTYRTASDVVINNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAEYNKLKQQADTILNEDANHVKTANRASQADIDGLVTKLQAALIDNQAAIAELDTKAQEKVTAAQQSKKVTQDEVAALVTKINNDKNNAIAEINKQTTAQGVTTEKDNGIAVLEQDVITPTVKPQAKQDIIQAVTTRKQQIKKSNASLQDEKDVANDKIGKIETKAIKDIDAATTNAQVEAIKTKAINDINQTTPATTAKAAALEEFDEVVQAQIDQAPLNPDTTNEEVAEAIERINAAKVSGVKAIEATTTAQDLERVKNEEISKIENITDSTQTKMDAYNEVKQAATARKAQNATVSNATNEEVAEADAAVDAAQKQGLHDIQVVKSKQEVADTKSKVLDKINAIQTQAKVKPAADTEVENAYNTRKQEIQNSNASTTEEKQAAYTELDTKKQEARTNLDAANTNSDVTTAKDNSIAAINQVQAATTKKSDAKAEIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQAVVTANADIDNAAANNDVDNAKTTNEATIAAITPDANVKPAAKQAIADKVQAQETAIDGNNGSTTEEKAAAKQQVQTEKTTADAAIDAAHTNAEVEAAKKAAIAKIEAIQPATTTKDNAKEAIATKANERKTAIAQTQDITAEEIAAANADVDNAVTQANSNIEAANSQNDVDQAKTTGENSIDQVTPTVNKKATARNEITAILNNKLQEIQATPDATDEEKQAADAEANTENGKANQAISAATTNAQVDEAKANAEAAINAVTPKVVKKQAAKDEIDQLQATQTNVINNDQNATTEEKEAAIQQLATAVTDAKNNITAATDDNGVDQAKDAGKNSIQSTQPATAVKSNAKNDVDQAVTTQNQAIDNTTGATTEEKNAAKDLVLKAKEKAYQDILNAQTTNDVTQIKDQAVADIQGITADTTIKDVAKDELATKANEQKALIAQTADATTEEKEQANQQVDAQLTQGNQNIENAQSIDDVNTAKDNAIQAIDPIQASTDVKTNARAELLTEMQNKITEILNNNETTNEEKGNDIGPVRAAYEEGLNNINAATTTGDVTTAKDTAVQKVQQLHANPVKKPAGKKELDQAAADKKTQIEQTPNASQQEINDAKQEVDTELNQAKTNVDQSSTNEYVDNAVKEGKAKINAVKTFSEYKKDALAKIEDAYNAKVNEADNSNASTSSEIAEAKQKLAELKQTADQNVNQATSKDDIEVQIHNDLDNINDYTIPTGKKESATTDLYAYADQKKNNISADTNATQDEKQQAIKQVDQNVQTALESINNGVDNGDVDDALTQGKAAIDAIQVDATVKPKANQAIEVKAEDTKESIDQSDQLTAEEKTEALAMIKQITDQAKQGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVNADATTEEKEAFTNALEDILSKATEDISDQTTNAEIATVKNSALEQLKAQRINPEVKKNALEAIREVVNKQIEIIKNADADASAKEIARTDLGRYFDRFADKLDKTQTNAEVAELQNVTIPAIEAIVPQNDPDANDTNNGIDNNDATANSNANATPENTGQPNVSETTANGKADASPTTPNNSDAATGETTATSATDDANDKPQANNNSSVDASTNSPTMDNDVTSKPEVESTNNGTTDKPVTETDNATPAESTTNNNSTTTATNENAPTGSTATAPTTASTEAASSADSKDNASVNDSKQNAEVNNSAESQSTNDKIAQPKSENKAKAEKDGSDSTNQSMVESTTETLPSADITEPNVPSNTSKDKEESTTNQTDAGQLKSETNVASNEADKSPSKADTEVSNKPSTSASSEAKEKMTSTNLSQKDDTATADTNDTQKSVGSAANNKATQNDGANASPATVSNGSNSANQDMLNVTNTDDHQAKTKSAQQGKVNKAKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKDQQTEE

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Crispr_ID: CP022906_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022906_12

2381259-2381452

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACTTGCA	CRT

3 spacers

The CRISPR arrays of CP022906_12

>merge|CP022906|12|2381259-2381452|CRT
TGTTGGGGCCCCGCCAACTTGCACATTATTGTATGCTGACTTTTCGTCACCTTCTGTGTTGGGGCCCCGTTCCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTATGCTGACTTTCTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTGTA

>CP022906|12|3|2381259-2381452|CRT
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTATGCTGACTTTTCGTCACCTTCTG
TGTTGGGGCCCCGTTCCCCAACT	TGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTA
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTATGCTGACTTTCTGTCAGCTTCTG
TGTTGGGGCCCCGCCAACTTGTA

Protein	Signature genes	Signature genes Name	Protein_function
CP022906.1\|AXJ81679.1\|2382635_2383235_-\|putative-molybdenum-cofactor-guanylyltransferase	unknown	unknown	gnl\|CDD\|234725
CP022906.1\|AXJ81673.1\|2377637_2377889_+\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ81687.1\|2388557_2389229_-\|Molybdenum-transport-system-permease-protein-ModB	unknown	unknown	gnl\|CDD\|226629
CP022906.1\|AXJ81678.1\|2381593_2382616_-\|Cyclic-pyranopterin-monophosphate-synthase	unknown	unknown	gnl\|CDD\|274250
CP022906.1\|AXJ81677.1\|2380552_2380903_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
CP022906.1\|AXJ81685.1\|2386777_2387782_-\|Molybdopterin-synthase-adenylyltransferase	unknown	unknown	gnl\|CDD\|181084
CP022906.1\|AXJ81668.1\|2370745_2371654_-\|Membrane-transport-protein	unknown	unknown	gnl\|CDD\|223751
CP022906.1\|AXJ81671.1\|2372699_2375867_-\|Swarming-motility-protein-SwrC	unknown	unknown	gnl\|CDD\|223911
CP022906.1\|AXJ81682.1\|2383940_2384426_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-adapter-protein	unknown	unknown	gnl\|CDD\|224677
CP022906.1\|AXJ81681.1\|2383480_2383927_-\|Molybdopterin-synthase-catalytic-subunit	unknown	unknown	gnl\|CDD\|223391
CP022906.1\|AXJ81686.1\|2387951_2388557_-\|Sulfate/thiosulfate-import-ATP-binding-protein-CysA	unknown	unknown	gnl\|CDD\|226628
CP022906.1\|AXJ81675.1\|2378806_2379247_+\|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
CP022906.1\|AXJ81676.1\|2379239_2380451_+\|major-facilitator-superfamily-transporter	unknown	unknown	gnl\|CDD\|341042
CP022906.1\|AXJ81680.1\|2383241_2383475_-\|Molybdopterin-synthase-sulfur-carrier-subunit	unknown	unknown	gnl\|CDD\|340452
CP022906.1\|AXJ81672.1\|2375983_2377249_-\|Lipid-II:glycine-glycyltransferase	unknown	unknown	gnl\|CDD\|225224
CP022906.1\|AXJ81684.1\|2386240_2386747_-\|Molybdenum-cofactor-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|223595
CP022906.1\|AXJ81669.1\|2371786_2371951_+\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ81670.1\|2372195_2372513_+\|hypothetical-protein	unknown	unknown	unknown
CP022906.1\|AXJ81674.1\|2377880_2378645_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379203
CP022906.1\|AXJ81683.1\|2384422_2385682_-\|Molybdopterin-molybdenumtransferase	unknown	unknown	gnl\|CDD\|238452

Protein	Function_ID	Function_description	E-value
CP022906.1\|AXJ81684.1\|2386240_2386747_-\|Molybdenum-cofactor-biosynthesis-protein-B	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	1.83065e-64
CP022906.1\|AXJ81685.1\|2386777_2387782_-\|Molybdopterin-synthase-adenylyltransferase	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	3.67241e-132
CP022906.1\|AXJ81687.1\|2388557_2389229_-\|Molybdenum-transport-system-permease-protein-ModB	gnl\|CDD\|226629	COG4149, ModC, ABC-type molybdate transport system, permease component [Inorganic ion transport and metabolism].	8.73868e-95
CP022906.1\|AXJ81678.1\|2381593_2382616_-\|Cyclic-pyranopterin-monophosphate-synthase	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
CP022906.1\|AXJ81677.1\|2380552_2380903_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
CP022906.1\|AXJ81679.1\|2382635_2383235_-\|putative-molybdenum-cofactor-guanylyltransferase	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
CP022906.1\|AXJ81671.1\|2372699_2375867_-\|Swarming-motility-protein-SwrC	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
CP022906.1\|AXJ81682.1\|2383940_2384426_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-adapter-protein	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50
CP022906.1\|AXJ81681.1\|2383480_2383927_-\|Molybdopterin-synthase-catalytic-subunit	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
CP022906.1\|AXJ81675.1\|2378806_2379247_+\|putative-HTH-type-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15
CP022906.1\|AXJ81676.1\|2379239_2380451_+\|major-facilitator-superfamily-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.68998e-72
CP022906.1\|AXJ81680.1\|2383241_2383475_-\|Molybdopterin-synthase-sulfur-carrier-subunit	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
CP022906.1\|AXJ81672.1\|2375983_2377249_-\|Lipid-II:glycine-glycyltransferase	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	4.8324e-143
CP022906.1\|AXJ81686.1\|2387951_2388557_-\|Sulfate/thiosulfate-import-ATP-binding-protein-CysA	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.32197e-115
CP022906.1\|AXJ81668.1\|2370745_2371654_-\|Membrane-transport-protein	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	5.44592e-42
CP022906.1\|AXJ81674.1\|2377880_2378645_-\|hypothetical-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	4.85733e-38
CP022906.1\|AXJ81683.1\|2384422_2385682_-\|Molybdopterin-molybdenumtransferase	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.49423e-160

>CP022906.1|AXJ81677.1|2380552_2380903_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>CP022906.1|AXJ81676.1|2379239_2380451_+|major-facilitator-superfamily-transporter
MTNQGSLNKSPIFTKSFTINFLVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGINLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>CP022906.1|AXJ81675.1|2378806_2379247_+|putative-HTH-type-transcriptional-regulator
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>CP022906.1|AXJ81674.1|2377880_2378645_-|hypothetical-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLHTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGTIYRFEPLV
>CP022906.1|AXJ81673.1|2377637_2377889_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLVIIHMGILAHSTYVYLY
>CP022906.1|AXJ81672.1|2375983_2377249_-|Lipid-II:glycine-glycyltransferase
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>CP022906.1|AXJ81671.1|2372699_2375867_-|Swarming-motility-protein-SwrC
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDIENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVLSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>CP022906.1|AXJ81670.1|2372195_2372513_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>CP022906.1|AXJ81669.1|2371786_2371951_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDIEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>CP022906.1|AXJ81668.1|2370745_2371654_-|Membrane-transport-protein
MTEQFTMIILLIALGYFLKRINFIKATDSQVIATLVLNVTLPSLVIVNLNSAELKLSFSILPILMIIYGIVAKMIAVWFFRKYDNHMRGSVGMMTGAMNIGLFAYPLIEVIWPKTGLIYFVMADIGGAFVMFGITYFVGSYFSEGSDQFDFKYLGKKLLQSVPLVTYIVMFILNISHIHLPHVAIDFFSILSHANMPLSMILLGVMLNFTLERKYIPATIKYLCLHYGLALVAGLLVYVLLPVSDDMIKTTLLVTWMFPVGVAIIFYGIQFKYRTLPFIGMTTNLTIIISIIILYVYQAVFV
>CP022906.1|AXJ81678.1|2381593_2382616_-|Cyclic-pyranopterin-monophosphate-synthase
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>CP022906.1|AXJ81679.1|2382635_2383235_-|putative-molybdenum-cofactor-guanylyltransferase
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>CP022906.1|AXJ81680.1|2383241_2383475_-|Molybdopterin-synthase-sulfur-carrier-subunit
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>CP022906.1|AXJ81681.1|2383480_2383927_-|Molybdopterin-synthase-catalytic-subunit
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>CP022906.1|AXJ81682.1|2383940_2384426_-|Molybdopterin-guanine-dinucleotide-biosynthesis-adapter-protein
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>CP022906.1|AXJ81683.1|2384422_2385682_-|Molybdopterin-molybdenumtransferase
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>CP022906.1|AXJ81684.1|2386240_2386747_-|Molybdenum-cofactor-biosynthesis-protein-B
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELIK
>CP022906.1|AXJ81685.1|2386777_2387782_-|Molybdopterin-synthase-adenylyltransferase
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>CP022906.1|AXJ81686.1|2387951_2388557_-|Sulfate/thiosulfate-import-ATP-binding-protein-CysA
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG
>CP022906.1|AXJ81687.1|2388557_2389229_-|Molybdenum-transport-system-permease-protein-ModB
MPDLTPFWISIRVAVISTIIVTVLGIFISKWLYRRKGSWVKVLESLLILPIVLPPTVLGFILLIIFSPRGPIGQFFANVLHLPVVFTLTGAVIASVIVSFPLMYQHTVQGFRGIDTKMINTARTMGASETKIFLKLILPLAKRSILAGIMMSFARALGEFGATLMVAGYIPNKTNTLPLEIYFLVEQGRENEAWLWVLVLVAFSIVVISTINLLNKDKYKEVD

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP022906_4	4.1\|816336\|29\|CP022906\|CRISPRCasFinder	816336-816364	29	CP022906.1	2848594-2848622	0	1.0
CP022906_6	6.1\|866336\|34\|CP022906\|CRISPRCasFinder	866336-866369	34	CP022906.1	1362794-1362827	0	1.0
CP022906_6	6.1\|866336\|34\|CP022906\|CRISPRCasFinder	866336-866369	34	CP022906.1	1451265-1451298	0	1.0
CP022906_8	8.2\|1151878\|37\|CP022906\|CRT	1151878-1151914	37	CP022906.1	378740-378776	0	1.0
CP022906_8	8.2\|1151878\|37\|CP022906\|CRT	1151878-1151914	37	CP022906.1	821766-821802	0	1.0
CP022906_8	8.2\|1151878\|37\|CP022906\|CRT	1151878-1151914	37	CP022906.1	1051149-1051185	0	1.0
CP022906_8	8.2\|1151878\|37\|CP022906\|CRT	1151878-1151914	37	CP022906.1	1362753-1362789	0	1.0
CP022906_8	8.3\|1151934\|37\|CP022906\|CRT	1151934-1151970	37	CP022906.1	152877-152913	0	1.0
CP022906_8	8.3\|1151934\|37\|CP022906\|CRT	1151934-1151970	37	CP022906.1	656957-656993	0	1.0
CP022906_8	8.3\|1151934\|37\|CP022906\|CRT	1151934-1151970	37	CP022906.1	774332-774368	0	1.0
CP022906_8	8.3\|1151934\|37\|CP022906\|CRT	1151934-1151970	37	CP022906.1	775302-775338	0	1.0
CP022906_8	8.3\|1151934\|37\|CP022906\|CRT	1151934-1151970	37	CP022906.1	821822-821858	0	1.0
CP022906_8	8.3\|1151934\|37\|CP022906\|CRT	1151934-1151970	37	CP022906.1	1362811-1362847	0	1.0
CP022906_8	8.3\|1151934\|37\|CP022906\|CRT	1151934-1151970	37	CP022906.1	1451245-1451281	0	1.0
CP022906_8	8.3\|1151934\|37\|CP022906\|CRT	1151934-1151970	37	CP022906.1	2063818-2063854	0	1.0
CP022906_4	4.1\|816336\|29\|CP022906\|CRISPRCasFinder	816336-816364	29	CP022906.1	378857-378885	1	0.966
CP022906_4	4.1\|816336\|29\|CP022906\|CRISPRCasFinder	816336-816364	29	CP022906.1	378912-378940	1	0.966
CP022906_4	4.1\|816336\|29\|CP022906\|CRISPRCasFinder	816336-816364	29	CP022906.1	1856989-1857017	1	0.966
CP022906_5	5.1\|821738\|26\|CP022906\|CRISPRCasFinder	821738-821763	26	CP022906.1	784730-784755	1	0.962
CP022906_5	5.1\|821738\|26\|CP022906\|CRISPRCasFinder	821738-821763	26	CP022906.1	1151973-1151998	1	0.962
CP022906_5	5.1\|821738\|26\|CP022906\|CRISPRCasFinder	821738-821763	26	CP022906.1	2848562-2848587	1	0.962
CP022906_7	7.1\|931131\|26\|CP022906\|CRT	931131-931156	26	CP022906.1	931075-931100	1	0.962
CP022906_7	7.3\|931245\|26\|CP022906\|CRT	931245-931270	26	CP022906.1	821794-821819	1	0.962
CP022906_8	8.1\|1151822\|37\|CP022906\|CRT	1151822-1151858	37	CP022906.1	1856986-1857022	1	0.973
CP022906_8	8.2\|1151878\|37\|CP022906\|CRT	1151878-1151914	37	CP022906.1	1451303-1451339	1	0.973
CP022906_8	8.2\|1151878\|37\|CP022906\|CRT	1151878-1151914	37	CP022906.1	1678561-1678597	1	0.973
CP022906_8	8.2\|1151878\|37\|CP022906\|CRT	1151878-1151914	37	CP022906.1	2664196-2664232	1	0.973
CP022906_8	8.3\|1151934\|37\|CP022906\|CRT	1151934-1151970	37	CP022906.1	1077283-1077319	1	0.973
CP022906_8	8.3\|1151934\|37\|CP022906\|CRT	1151934-1151970	37	CP022906.1	2549323-2549359	1	0.973
CP022906_10	10.1\|2062369\|33\|CP022906\|CRISPRCasFinder	2062369-2062401	33	CP022906.1	821774-821806	1	0.97
CP022906_10	10.1\|2062369\|33\|CP022906\|CRISPRCasFinder	2062369-2062401	33	CP022906.1	1362749-1362781	1	0.97
CP022906_10	10.1\|2062369\|33\|CP022906\|CRISPRCasFinder	2062369-2062401	33	CP022906.1	1678569-1678601	1	0.97
CP022906_10	10.1\|2062369\|33\|CP022906\|CRISPRCasFinder	2062369-2062401	33	CP022906.1	2664204-2664236	1	0.97
CP022906_12	12.2\|2381338\|36\|CP022906\|CRT	2381338-2381373	36	CP022906.1	1856982-1857017	1	0.972
CP022906_4	4.1\|816336\|29\|CP022906\|CRISPRCasFinder	816336-816364	29	CP022906.1	866378-866406	2	0.931
CP022906_4	4.1\|816336\|29\|CP022906\|CRISPRCasFinder	816336-816364	29	CP022906.1	950770-950798	2	0.931
CP022906_4	4.1\|816336\|29\|CP022906\|CRISPRCasFinder	816336-816364	29	CP022906.1	1678508-1678536	2	0.931
CP022906_4	4.1\|816336\|29\|CP022906\|CRISPRCasFinder	816336-816364	29	CP022906.1	2073113-2073141	2	0.931
CP022906_4	4.1\|816336\|29\|CP022906\|CRISPRCasFinder	816336-816364	29	CP022906.1	2574609-2574637	2	0.931
CP022906_5	5.1\|821738\|26\|CP022906\|CRISPRCasFinder	821738-821763	26	CP022906.1	784786-784811	2	0.923
CP022906_5	5.1\|821738\|26\|CP022906\|CRISPRCasFinder	821738-821763	26	CP022906.1	931075-931100	2	0.923
CP022906_7	7.1\|931131\|26\|CP022906\|CRT	931131-931156	26	CP022906.1	784730-784755	2	0.923
CP022906_7	7.1\|931131\|26\|CP022906\|CRT	931131-931156	26	CP022906.1	1151973-1151998	2	0.923
CP022906_7	7.1\|931131\|26\|CP022906\|CRT	931131-931156	26	CP022906.1	2848562-2848587	2	0.923
CP022906_7	7.3\|931245\|26\|CP022906\|CRT	931245-931270	26	CP022906.1	378723-378748	2	0.923
CP022906_8	8.1\|1151822\|37\|CP022906\|CRT	1151822-1151858	37	CP022906.1	866373-866409	2	0.946
CP022906_8	8.1\|1151822\|37\|CP022906\|CRT	1151822-1151858	37	CP022906.1	1678503-1678539	2	0.946
CP022906_8	8.1\|1151822\|37\|CP022906\|CRT	1151822-1151858	37	CP022906.1	2073108-2073144	2	0.946
CP022906_8	8.1\|1151822\|37\|CP022906\|CRT	1151822-1151858	37	CP022906.1	2574606-2574642	2	0.946
CP022906_8	8.1\|1151822\|37\|CP022906\|CRT	1151822-1151858	37	CP022906.1	2848589-2848625	2	0.946
CP022906_8	8.2\|1151878\|37\|CP022906\|CRT	1151878-1151914	37	CP022906.1	1147910-1147946	2	0.946
CP022906_8	8.2\|1151878\|37\|CP022906\|CRT	1151878-1151914	37	CP022906.1	1151990-1152026	2	0.946
CP022906_8	8.3\|1151934\|37\|CP022906\|CRT	1151934-1151970	37	CP022906.1	1147966-1148002	2	0.946
CP022906_10	10.1\|2062369\|33\|CP022906\|CRISPRCasFinder	2062369-2062401	33	CP022906.1	1451311-1451343	2	0.939
CP022906_12	12.1\|2381282\|33\|CP022906\|CRT	2381282-2381314	33	CP022906.1	821774-821806	2	0.939
CP022906_12	12.1\|2381282\|33\|CP022906\|CRT	2381282-2381314	33	CP022906.1	1362749-1362781	2	0.939
CP022906_12	12.1\|2381282\|33\|CP022906\|CRT	2381282-2381314	33	CP022906.1	1451311-1451343	2	0.939
CP022906_12	12.1\|2381282\|33\|CP022906\|CRT	2381282-2381314	33	CP022906.1	2664204-2664236	2	0.939
CP022906_12	12.2\|2381338\|36\|CP022906\|CRT	2381338-2381373	36	CP022906.1	1678508-1678543	2	0.944
CP022906_12	12.2\|2381338\|36\|CP022906\|CRT	2381338-2381373	36	CP022906.1	2073113-2073148	2	0.944

1. spacer 4.1|816336|29|CP022906|CRISPRCasFinder matches to position: 2848594-2848622, mismatch: 0, identity: 1.0

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtttgtagaatttcttttcgaaa	Protospacer
*****************************

2. spacer 6.1|866336|34|CP022906|CRISPRCasFinder matches to position: 1362794-1362827, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

3. spacer 6.1|866336|34|CP022906|CRISPRCasFinder matches to position: 1451265-1451298, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

4. spacer 8.2|1151878|37|CP022906|CRT matches to position: 378740-378776, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

5. spacer 8.2|1151878|37|CP022906|CRT matches to position: 821766-821802, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

6. spacer 8.2|1151878|37|CP022906|CRT matches to position: 1051149-1051185, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

7. spacer 8.2|1151878|37|CP022906|CRT matches to position: 1362753-1362789, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

8. spacer 8.3|1151934|37|CP022906|CRT matches to position: 152877-152913, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

9. spacer 8.3|1151934|37|CP022906|CRT matches to position: 656957-656993, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

10. spacer 8.3|1151934|37|CP022906|CRT matches to position: 774332-774368, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

11. spacer 8.3|1151934|37|CP022906|CRT matches to position: 775302-775338, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

12. spacer 8.3|1151934|37|CP022906|CRT matches to position: 821822-821858, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

13. spacer 8.3|1151934|37|CP022906|CRT matches to position: 1362811-1362847, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

14. spacer 8.3|1151934|37|CP022906|CRT matches to position: 1451245-1451281, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

15. spacer 8.3|1151934|37|CP022906|CRT matches to position: 2063818-2063854, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

16. spacer 4.1|816336|29|CP022906|CRISPRCasFinder matches to position: 378857-378885, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcttgtagaatttcttttcgaaa	Protospacer
*******.*********************

17. spacer 4.1|816336|29|CP022906|CRISPRCasFinder matches to position: 378912-378940, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcttgtagaatttcttttcgaaa	Protospacer
*******.*********************

18. spacer 4.1|816336|29|CP022906|CRISPRCasFinder matches to position: 1856989-1857017, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaa	Protospacer
********.********************

19. spacer 5.1|821738|26|CP022906|CRISPRCasFinder matches to position: 784730-784755, mismatch: 1, identity: 0.962

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgcctgcttctgtgttggggccccg	Protospacer
***** ********************

20. spacer 5.1|821738|26|CP022906|CRISPRCasFinder matches to position: 1151973-1151998, mismatch: 1, identity: 0.962

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
************.*************

21. spacer 5.1|821738|26|CP022906|CRISPRCasFinder matches to position: 2848562-2848587, mismatch: 1, identity: 0.962

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
************.*************

22. spacer 7.1|931131|26|CP022906|CRT matches to position: 931075-931100, mismatch: 1, identity: 0.962

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacacagaggctggtgg	Protospacer
***********************.**

23. spacer 7.3|931245|26|CP022906|CRT matches to position: 821794-821819, mismatch: 1, identity: 0.962

cggggccccaacacagaagctggcga	CRISPR spacer
cggggccccaacacagaagctgacga	Protospacer
**********************.***

24. spacer 8.1|1151822|37|CP022906|CRT matches to position: 1856986-1857022, mismatch: 1, identity: 0.973

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacagacaatgcaagttg	Protospacer
*******.*****************************

25. spacer 8.2|1151878|37|CP022906|CRT matches to position: 1451303-1451339, mismatch: 1, identity: 0.973

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agatgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
** **********************************

26. spacer 8.2|1151878|37|CP022906|CRT matches to position: 1678561-1678597, mismatch: 1, identity: 0.973

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttactataatgtgcaagtt	Protospacer
********************** **************

27. spacer 8.2|1151878|37|CP022906|CRT matches to position: 2664196-2664232, mismatch: 1, identity: 0.973

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcgagtt	Protospacer
********************************.****

28. spacer 8.3|1151934|37|CP022906|CRT matches to position: 1077283-1077319, mismatch: 1, identity: 0.973

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgtaagtt	Protospacer
*******************************.*****

29. spacer 8.3|1151934|37|CP022906|CRT matches to position: 2549323-2549359, mismatch: 1, identity: 0.973

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctagagacaatgcaagtt	Protospacer
********************** **************

30. spacer 10.1|2062369|33|CP022906|CRISPRCasFinder matches to position: 821774-821806, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

31. spacer 10.1|2062369|33|CP022906|CRISPRCasFinder matches to position: 1362749-1362781, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

32. spacer 10.1|2062369|33|CP022906|CRISPRCasFinder matches to position: 1678569-1678601, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattatagtaagctgacttttcgtcagcttctg	Protospacer
****** **************************

33. spacer 10.1|2062369|33|CP022906|CRISPRCasFinder matches to position: 2664204-2664236, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

34. spacer 12.2|2381338|36|CP022906|CRT matches to position: 1856982-1857017, mismatch: 1, identity: 0.972

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaattctcta	Protospacer
************************.***********

35. spacer 4.1|816336|29|CP022906|CRISPRCasFinder matches to position: 866378-866406, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

36. spacer 4.1|816336|29|CP022906|CRISPRCasFinder matches to position: 950770-950798, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

37. spacer 4.1|816336|29|CP022906|CRISPRCasFinder matches to position: 1678508-1678536, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

38. spacer 4.1|816336|29|CP022906|CRISPRCasFinder matches to position: 2073113-2073141, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttcctttcgaaa	Protospacer
********.***********.********

39. spacer 4.1|816336|29|CP022906|CRISPRCasFinder matches to position: 2574609-2574637, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

40. spacer 5.1|821738|26|CP022906|CRISPRCasFinder matches to position: 784786-784811, mismatch: 2, identity: 0.923

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgcctgcttctatgttggggccccg	Protospacer
***** ******.*************

41. spacer 5.1|821738|26|CP022906|CRISPRCasFinder matches to position: 931075-931100, mismatch: 2, identity: 0.923

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccaccagcctctgtgttggggccccg	Protospacer
**.*****.*****************

42. spacer 7.1|931131|26|CP022906|CRT matches to position: 784730-784755, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacacagaagcaggcgg	Protospacer
*****************.** *****

43. spacer 7.1|931131|26|CP022906|CRT matches to position: 1151973-1151998, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
*************.***.********

44. spacer 7.1|931131|26|CP022906|CRT matches to position: 2848562-2848587, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
*************.***.********

45. spacer 7.3|931245|26|CP022906|CRT matches to position: 378723-378748, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggcga	CRISPR spacer
cggggccccaacaaagaagctgacga	Protospacer
************* ********.***

46. spacer 8.1|1151822|37|CP022906|CRT matches to position: 866373-866409, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacaggcaatgcaagttg	Protospacer
*******.****************.************

47. spacer 8.1|1151822|37|CP022906|CRT matches to position: 1678503-1678539, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacaggcaatgcaagttg	Protospacer
*******.****************.************

48. spacer 8.1|1151822|37|CP022906|CRT matches to position: 2073108-2073144, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaggaaattctacagacaatgcaagttg	Protospacer
*******.***.*************************

49. spacer 8.1|1151822|37|CP022906|CRT matches to position: 2574606-2574642, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacaggcaatgcaagttg	Protospacer
*******.****************.************

50. spacer 8.1|1151822|37|CP022906|CRT matches to position: 2848589-2848625, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacaaacaatgcaagttg	Protospacer
*******.***************.*************

51. spacer 8.2|1151878|37|CP022906|CRT matches to position: 1147910-1147946, mismatch: 2, identity: 0.946

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctggcgaaaagtcagcttacaaaaatgtgcaagtt	Protospacer
*****.****************** ************

52. spacer 8.2|1151878|37|CP022906|CRT matches to position: 1151990-1152026, mismatch: 2, identity: 0.946

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
*****.**.****************************

53. spacer 8.3|1151934|37|CP022906|CRT matches to position: 1147966-1148002, mismatch: 2, identity: 0.946

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggaaccccaatttctacagacaatgcaagtt	Protospacer
********* .**************************

54. spacer 10.1|2062369|33|CP022906|CRISPRCasFinder matches to position: 1451311-1451343, mismatch: 2, identity: 0.939

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcatcttctg	Protospacer
******.******************* ******

55. spacer 12.1|2381282|33|CP022906|CRT matches to position: 821774-821806, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

56. spacer 12.1|2381282|33|CP022906|CRT matches to position: 1362749-1362781, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

57. spacer 12.1|2381282|33|CP022906|CRT matches to position: 1451311-1451343, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcatcttctg	Protospacer
********** ***************.******

58. spacer 12.1|2381282|33|CP022906|CRT matches to position: 2664204-2664236, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

59. spacer 12.2|2381338|36|CP022906|CRT matches to position: 1678508-1678543, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaattctcta	Protospacer
*******.****************.***********

60. spacer 12.2|2381338|36|CP022906|CRT matches to position: 2073113-2073148, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcctttcgaaattctcta	Protospacer
********************.***.***********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP022906_1	1.1\|46254\|53\|CP022906\|CRISPRCasFinder	46254-46306	53	NZ_LR735436	Staphylococcus epidermidis strain none isolate Se_BPH0736 plasmid 3	9028-9080	1	0.981
CP022906_7	7.4\|931301\|53\|CP022906\|CRT	931301-931353	53	MG543995	Staphylococcus phage UPMK_1, partial genome	76246-76298	4	0.925
CP022906_5	5.1\|821738\|26\|CP022906\|CRISPRCasFinder	821738-821763	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808
CP022906_5	5.1\|821738\|26\|CP022906\|CRISPRCasFinder	821738-821763	26	NZ_CP034332	Tabrizicola piscis strain K13M18 plasmid unnamed4, complete sequence	3359-3384	5	0.808
CP022906_5	5.1\|821738\|26\|CP022906\|CRISPRCasFinder	821738-821763	26	NZ_CP022605	Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence	715511-715536	5	0.808
CP022906_7	7.3\|931245\|26\|CP022906\|CRT	931245-931270	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808
CP022906_4	4.1\|816336\|29\|CP022906\|CRISPRCasFinder	816336-816364	29	MN693281	Marine virus AFVG_25M371, complete genome	6448-6476	7	0.759
CP022906_10	10.1\|2062369\|33\|CP022906\|CRISPRCasFinder	2062369-2062401	33	NC_021536	Synechococcus phage S-IOM18 genomic sequence	159745-159777	10	0.697

1. spacer 1.1|46254|53|CP022906|CRISPRCasFinder matches to NZ_LR735436 (Staphylococcus epidermidis strain none isolate Se_BPH0736 plasmid 3) position: , mismatch: 1, identity: 0.981

ctataataactaacgaaagaattataacacctattatatagagaataaagttt	CRISPR spacer
ctataataactaacgaaagaattataacacctattatatagagaataaagatt	Protospacer
************************************************** **

2. spacer 7.4|931301|53|CP022906|CRT matches to MG543995 (Staphylococcus phage UPMK_1, partial genome) position: , mismatch: 4, identity: 0.925

ggtgggacgacgaaataaattttgcgaaaatatcatttctgtcccactcccaa	CRISPR spacer
ggtgggacgacgaaataaattttgagaaactatcatttctgtcccactccctt	Protospacer
************************ **** *********************

3. spacer 5.1|821738|26|CP022906|CRISPRCasFinder matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
acgccagcttctgtgttgaggcctta	Protospacer
 *****************.****...

4. spacer 5.1|821738|26|CP022906|CRISPRCasFinder matches to NZ_CP034332 (Tabrizicola piscis strain K13M18 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctgtgtctgggcctac	Protospacer
****************. *****.

5. spacer 5.1|821738|26|CP022906|CRISPRCasFinder matches to NZ_CP022605 (Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctgtgtttggccctga	Protospacer
***************** ** **. .

6. spacer 7.3|931245|26|CP022906|CRT matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

cggggccccaacacagaagctggcga	CRISPR spacer
taaggcctcaacacagaagctggcgt	Protospacer
...****.*****************

7. spacer 4.1|816336|29|CP022906|CRISPRCasFinder matches to MN693281 (Marine virus AFVG_25M371, complete genome) position: , mismatch: 7, identity: 0.759

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtttgtaggatttcttctaagtg	Protospacer
**************.*******.* .. .

8. spacer 10.1|2062369|33|CP022906|CRISPRCasFinder matches to NC_021536 (Synechococcus phage S-IOM18 genomic sequence) position: , mismatch: 10, identity: 0.697

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
ttttatcgtaaggtgagttttcgtcaagcacct	Protospacer
. ********** *** *********. . *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

52470 : 58311

Streptococcus_phage(75.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ79544.1\|52470_53145_+	Integrase core domain protein	A0A0N9SKD3	Staphylococcus_phage	6.2e-129	100.0
AXJ79545.1\|53186_53549_-	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor	A0A1B0RXM1	Streptococcus_phage	1.2e-57	100.0
AXJ79546.1\|53824_54619_-	Aminoglycoside 3'-phosphotransferase	E4ZFP6	Streptococcus_phage	2.3e-154	100.0
AXJ79547.1\|54711_55254_-	TDP-fucosamine acetyltransferase	A0A1B0RXL7	Streptococcus_phage	2.0e-93	99.4
AXJ79548.1\|55250_56159_-	Aminoglycoside 6-adenylyltransferase	E4ZFP8	Streptococcus_phage	2.8e-177	100.0
AXJ79549.1\|56191_56926_-	putative methyltransferase YcgJ	A0A1X9I6N4	Streptococcus_phage	1.5e-141	100.0
AXJ79550.1\|56906_57590_-	hypothetical protein	A0A1X9I6C9	Streptococcus_phage	4.1e-128	99.1
AXJ79551.1\|57636_58311_-	Integrase core domain protein	A0A0N9RU54	Staphylococcus_phage	2.0e-127	99.1

DBSCAN-SWA_2

753421 : 761241

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ80166.1\|753421_754477_-	Histidine protein kinase SaeS	A0A1V0SGX0	Hokovirus	2.1e-14	30.0
AXJ80167.1\|754476_755163_-	Response regulator SaeR	NA	NA	NA	NA
AXJ80168.1\|755137_755611_-	DoxX	NA	NA	NA	NA
AXJ80169.1\|755952_756393_-	Electron transfer DM13	NA	NA	NA	NA
AXJ80170.1\|756672_757257_-	hypothetical protein	NA	NA	NA	NA
AXJ80171.1\|757355_758069_-	7-carboxy-7-deazaguanine synthase	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
AXJ80172.1\|758072_758492_-	6-carboxy-5,6,7,8-tetrahydropterin synthase	S4U060	uncultured_phage	6.3e-07	28.7
AXJ80173.1\|758493_759162_-	7-cyano-7-deazaguanine synthase	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
AXJ80174.1\|759512_760106_+	Anthranilate synthase component 2	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
AXJ80175.1\|760089_761241_+	Aminodeoxychorismate synthase component 1	A0A0B5J984	Pandoravirus	1.6e-23	35.7

DBSCAN-SWA_3

773213 : 787944

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ80184.1\|773213_774272_+	Histidinol-phosphate aminotransferase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
AXJ80185.1\|774622_775165_+	Putative 5'(3')-deoxyribonucleotidase	NA	NA	NA	NA
AXJ80186.1\|775788_776706_-	Putative lipid kinase	A0A1V0SBJ0	Catovirus	3.7e-07	22.0
AXJ80187.1\|776975_778481_-	Di-/tripeptide transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
AXJ80188.1\|778821_779322_-	NADPH-dependent 7-cyano-7-deazaguanine reductase	E7DN65	Pneumococcus_phage	5.9e-52	71.5
AXJ80189.1\|779341_780208_-	EamA-like transporter family protein	NA	NA	NA	NA
AXJ80190.1\|781008_781407_+	ribonucleotide reductase stimulatory protein	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
AXJ80191.1\|781369_783475_+	Ribonucleoside-diphosphate reductase subunit alpha 2	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
AXJ80192.1\|783592_784564_+	Ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
AXJ80193.1\|785229_786243_+	Fe(3+) dicitrate transport system permease protein FecD	A0A2H4IY97	uncultured_Caudovirales_phage	2.2e-138	78.0
AXJ80194.1\|786229_787186_+	Iron-uptake system permease protein FeuC	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
AXJ80195.1\|787182_787944_+	putative siderophore transport system ATP-binding protein YusV	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6

DBSCAN-SWA_4

867874 : 889083

Staphylococcus_phage(77.78%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ80273.1\|867874_868900_+	Methionine import ATP-binding protein MetN 2	G9BWD6	Planktothrix_phage	1.2e-27	36.8
AXJ80274.1\|868892_869588_+	Methionine import system permease protein MetP	NA	NA	NA	NA
AXJ80275.1\|869605_870427_+	Methionine-binding lipoprotein MetQ precursor	NA	NA	NA	NA
AXJ80276.1\|870569_871790_-	Transposase	Q4ZE80	Staphylococcus_phage	6.4e-100	47.5
AXJ80277.1\|871878_872607_-	Enterotoxin type A precursor	A0EX09	Staphylococcus_phage	1.9e-22	32.3
AXJ80278.1\|872910_873360_-	Enterotoxin type E precursor	A0EX09	Staphylococcus_phage	7.3e-09	32.8
AXJ80279.1\|873429_873861_-	hypothetical protein	Q4ZCB6	Staphylococcus_virus	5.1e-36	56.0
AXJ80280.1\|873877_874336_-	hypothetical protein	A0A0H4J322	Staphylococcus_phage	5.1e-66	83.0
AXJ80281.1\|874347_874680_-	helix-turn-helix protein	A0A1J0MFC1	Staphylococcus_phage	1.6e-37	74.5
AXJ80282.1\|874872_875112_+	helix-turn-helix protein	A0A2H4J9X2	uncultured_Caudovirales_phage	1.7e-33	88.6
AXJ80283.1\|875127_875400_+	hypothetical protein	Q4ZE77	Staphylococcus_phage	9.7e-41	90.0
AXJ80284.1\|875411_875558_+	hypothetical protein	NA	NA	NA	NA
AXJ80285.1\|875550_875760_+	hypothetical protein	Q4ZE76	Staphylococcus_phage	1.7e-29	94.2
AXJ80286.1\|875762_876083_+	hypothetical protein	Q4ZE75	Staphylococcus_phage	1.3e-20	51.9
AXJ80287.1\|876146_877016_+	hypothetical protein	A0A1W6JQL5	Staphylococcus_phage	3.4e-156	92.7
AXJ80288.1\|877032_878490_+	Virulence-associated protein E	A0A1W6JQD6	Staphylococcus_phage	1.0e-277	96.1
AXJ80289.1\|878790_879153_+	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	8.9e-66	99.2
AXJ80290.1\|879154_879439_+	hypothetical protein	A0A1W6JQE4	Staphylococcus_phage	1.9e-47	95.7
AXJ80291.1\|879435_880077_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	1.5e-108	91.5
AXJ80292.1\|880593_880935_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	1.4e-57	99.1
AXJ80293.1\|880946_881525_+	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	1.4e-28	38.4
AXJ80294.1\|881542_881761_+	hypothetical protein	NA	NA	NA	NA
AXJ80295.1\|881811_882339_+	hypothetical protein	A0A1W6JQH7	Staphylococcus_phage	3.5e-87	97.1
AXJ80296.1\|882341_882683_+	hypothetical protein	A0A1W6JQM3	Staphylococcus_phage	1.4e-57	98.2
AXJ80297.1\|882679_883249_+	Terminase small subunit	Q4ZE85	Staphylococcus_phage	1.0e-100	97.9
AXJ80298.1\|883556_884357_+	Enterotoxin type B precursor	A0A097PAT7	Streptococcus_pyogenes_phage	1.0e-53	49.4
AXJ80299.1\|884434_884992_-	hypothetical protein	A0A1W6JQE5	Staphylococcus_phage	1.4e-70	73.8
AXJ80300.1\|885388_885517_+	hypothetical protein	A0A0F6N3H2	Staphylococcus_phage	1.1e-15	100.0
AXJ80301.1\|885587_885698_+	hypothetical protein	W5R8J7	Staphylococcus_phage	2.4e-11	94.4
AXJ80302.1\|885699_885885_+	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.7e-26	100.0
AXJ80303.1\|886715_886910_+	CsbD-like protein	NA	NA	NA	NA
AXJ80304.1\|887142_887994_-	hypothetical protein	NA	NA	NA	NA
AXJ80305.1\|888321_889083_+	YurY	A0A1V0SE00	Indivirus	4.4e-06	23.3

DBSCAN-SWA_5

1505267 : 1593674

102

Staphylococcus_phage(78.67%)

head,terminase,protease,tRNA,capsid,tail,lysis,holin,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ80841.1\|1505267_1506560_-\|tRNA	Asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.9e-54	30.0
AXJ80842.1\|1506881_1509575_-	hypothetical protein	A0A1X9I5C8	Streptococcus_phage	8.2e-47	34.4
AXJ80843.1\|1509598_1510570_-	Bifunctional ligase/repressor BirA	NA	NA	NA	NA
AXJ80844.1\|1510556_1511759_-	CCA-adding enzyme	H7BUW3	unidentified_phage	3.2e-35	42.5
AXJ80845.1\|1511763_1512906_-	GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase	NA	NA	NA	NA
AXJ80846.1\|1513146_1513464_-	nucleoside triphosphate pyrophosphohydrolase	NA	NA	NA	NA
AXJ80847.1\|1513800_1514499_-	Putative neutral zinc metallopeptidase	NA	NA	NA	NA
AXJ80848.1\|1514552_1515140_-	hypothetical protein	NA	NA	NA	NA
AXJ80849.1\|1515129_1515717_-	hypothetical protein	G3MAV7	Bacillus_virus	2.8e-08	27.2
AXJ80850.1\|1515718_1516963_-	tetratricopeptide repeat protein	NA	NA	NA	NA
AXJ80851.1\|1516969_1518268_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
AXJ80852.1\|1518277_1519342_-	3-dehydroquinate synthase	NA	NA	NA	NA
AXJ80853.1\|1519367_1520534_-	Chorismate synthase	A0A291AU41	Pandoravirus	7.6e-34	32.1
AXJ80854.1\|1520919_1521120_-	hypothetical protein	NA	NA	NA	NA
AXJ80855.1\|1521328_1521778_-	Nucleoside diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
AXJ80856.1\|1521869_1522829_-	Heptaprenyl diphosphate synthase component 2	A0A1V0SE37	Indivirus	1.3e-10	24.4
AXJ80857.1\|1522830_1523556_-	Demethylmenaquinone methyltransferase	NA	NA	NA	NA
AXJ80858.1\|1523558_1524131_-	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1	NA	NA	NA	NA
AXJ80859.1\|1524561_1524834_-	DNA-binding protein HU	A7KV42	Bacillus_phage	4.2e-28	73.3
AXJ80860.1\|1525004_1526003_-	Glycerol-3-phosphate dehydrogenase [NAD(P)+]	NA	NA	NA	NA
AXJ80861.1\|1526019_1527330_-	GTPase Der	NA	NA	NA	NA
AXJ80862.1\|1527551_1528727_-	30S ribosomal protein S1	NA	NA	NA	NA
AXJ80863.1\|1529438_1530098_-	Cytidylate kinase	NA	NA	NA	NA
AXJ80864.1\|1530174_1531143_+	putative L-asparaginase	NA	NA	NA	NA
AXJ80865.1\|1531257_1532244_-	Glucosaminate ammonia-lyase	NA	NA	NA	NA
AXJ80866.1\|1532645_1534106_-	Elastin-binding protein EbpS	NA	NA	NA	NA
AXJ80867.1\|1534258_1535638_-	ATP-dependent DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	2.9e-56	33.6
AXJ80868.1\|1535627_1536581_-	hypothetical protein	NA	NA	NA	NA
AXJ80869.1\|1536688_1536937_+	Ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
AXJ80870.1\|1537042_1537588_-	Riboflavin transporter RibU	NA	NA	NA	NA
AXJ80871.1\|1538184_1539099_-	hypothetical protein	NA	NA	NA	NA
AXJ80872.1\|1539113_1539320_-	hypothetical protein	NA	NA	NA	NA
AXJ80873.1\|1539312_1540191_-	hypothetical protein	NA	NA	NA	NA
AXJ80874.1\|1540308_1541226_-	hypothetical protein	NA	NA	NA	NA
AXJ80875.1\|1541316_1541664_-	hypothetical protein	Q4ZCJ7	Staphylococcus_virus	3.0e-26	100.0
AXJ80876.1\|1541714_1542398_-	hypothetical protein	A0A0A7S0U2	Clostridium_phage	1.1e-13	28.3
AXJ80877.1\|1542394_1542718_-	hypothetical protein	NA	NA	NA	NA
AXJ80878.1\|1542674_1543724_-	hypothetical protein	NA	NA	NA	NA
AXJ80879.1\|1544342_1545797_-	putative cell wall hydrolase LytN precursor	I1W626	Staphylococcus_phage	4.1e-287	99.0
AXJ80880.1\|1545807_1546110_-\|holin,lysis	Phage lysis protein, holin	A0A2I6PF56	Staphylococcus_phage	3.1e-48	100.0
AXJ80881.1\|1546245_1546545_-	hypothetical protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
AXJ80882.1\|1546590_1546755_-	hypothetical protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
AXJ80883.1\|1546747_1547137_-	hypothetical protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
AXJ80884.1\|1547136_1548603_-	hypothetical protein	A0A2I6PDE3	Staphylococcus_phage	2.0e-257	94.3
AXJ80885.1\|1548602_1550513_-	hypothetical protein	A0A2I6PEQ9	Staphylococcus_phage	0.0e+00	100.0
AXJ80886.1\|1550528_1550819_-	hypothetical protein	U5U457	Staphylococcus_phage	2.1e-49	100.0
AXJ80887.1\|1550818_1552402_-\|tail	Prophage endopeptidase tail	A0A2I6PEQ5	Staphylococcus_phage	9.3e-309	100.0
AXJ80888.1\|1552410_1553235_-\|tail	Phage tail protein	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
AXJ80889.1\|1553234_1559435_-	Glycyl-glycine endopeptidase ALE-1 precursor	U5U762	Staphylococcus_phage	0.0e+00	99.8
AXJ80890.1\|1559448_1559607_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
AXJ80891.1\|1559648_1559999_-	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
AXJ80892.1\|1560056_1560512_-	Bacterial Ig-like domain (group 2)	A0A2I6PER6	Staphylococcus_phage	5.7e-78	100.0
AXJ80893.1\|1560603_1561245_-\|tail	Phage major tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
AXJ80894.1\|1561279_1561675_-	hypothetical protein	A0A2I6PDD8	Staphylococcus_phage	2.6e-66	100.0
AXJ80895.1\|1561675_1562077_-	hypothetical protein	A0A2I6PDD3	Staphylococcus_phage	6.2e-68	100.0
AXJ80896.1\|1562073_1562406_-	hypothetical protein	A0A2I6PDD6	Staphylococcus_phage	6.2e-58	100.0
AXJ80897.1\|1562417_1562696_-\|head,tail	Phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
AXJ80898.1\|1562764_1563928_-\|capsid	Phage capsid family protein	A0A2I6PDD7	Staphylococcus_phage	9.4e-218	100.0
AXJ80899.1\|1563939_1564713_-\|protease	ATP-dependent Clp protease proteolytic subunit 1	M1TAZ4	Staphylococcus_phage	2.7e-136	99.6
AXJ80900.1\|1564696_1565935_-\|portal	Phage portal protein	A0A2K9VBP0	Staphylococcus_phage	6.9e-235	100.0
AXJ80901.1\|1565939_1567631_-	Phage Terminase	A0A2I6PE44	Staphylococcus_phage	0.0e+00	99.6
AXJ80902.1\|1567620_1567926_-\|terminase	Phage terminase, small subunit	A0A2I6PE27	Staphylococcus_phage	2.9e-49	100.0
AXJ80903.1\|1568054_1568369_-	HNH endonuclease	Q4ZCU3	Staphylococcus_virus	2.5e-56	100.0
AXJ80904.1\|1568525_1568963_-	hypothetical protein	A0A2I6PEB8	Staphylococcus_phage	1.0e-76	100.0
AXJ80905.1\|1568975_1570334_-	hypothetical protein	A0A0K1LKG3	Staphylococcus_phage	1.2e-259	98.7
AXJ80906.1\|1570323_1570614_-	VRR-NUC domain protein	U5U7A3	Staphylococcus_phage	4.9e-51	100.0
AXJ80907.1\|1570954_1573402_-	Virulence-associated protein E	B5WZN5	Staphylococcus_phage	0.0e+00	99.9
AXJ80908.1\|1573454_1573655_-	hypothetical protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
AXJ80909.1\|1573722_1573878_-	Transcriptional activator RinB	B5WZN3	Staphylococcus_phage	1.2e-19	100.0
AXJ80910.1\|1573867_1574104_-	hypothetical protein	A7TWB3	Staphylococcus_phage	1.9e-37	100.0
AXJ80911.1\|1574128_1574365_-	hypothetical protein	C8CH06	Staphylococcus_phage	3.1e-35	98.7
AXJ80912.1\|1574401_1574938_-	dUTPase	S4V978	Staphylococcus_phage	1.0e-94	98.9
AXJ80913.1\|1574930_1575113_-	hypothetical protein	D2JGL7	Staphylococcus_phage	2.6e-26	100.0
AXJ80914.1\|1575102_1575357_-	hypothetical protein	W5R8J0	Staphylococcus_phage	5.0e-39	100.0
AXJ80915.1\|1575368_1575611_-	hypothetical protein	A0A2D1G5G2	Staphylococcus_phage	5.6e-40	98.8
AXJ80916.1\|1575625_1575826_-	hypothetical protein	A0A2I6PEM3	Staphylococcus_phage	2.5e-30	100.0
AXJ80917.1\|1575828_1576086_-	hypothetical protein	A0A2I6PEN5	Staphylococcus_phage	2.6e-43	100.0
AXJ80918.1\|1576085_1576487_-	PVL ORF-50-like family protein	A0A2I6PEL5	Staphylococcus_phage	2.3e-67	99.2
AXJ80919.1\|1576486_1576672_-	hypothetical protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
AXJ80920.1\|1576684_1578646_-	DNA polymerase I, thermostable	A0A2I6PE86	Staphylococcus_phage	0.0e+00	100.0
AXJ80921.1\|1578704_1579262_-	hypothetical protein	A0A2K9VBT2	Staphylococcus_phage	1.8e-97	100.0
AXJ80922.1\|1579287_1580454_-	PD-(D/E)XK nuclease superfamily protein	A0A0K1LKE3	Staphylococcus_phage	1.6e-220	99.7
AXJ80923.1\|1580450_1580813_-	hypothetical protein	A0A2I6PF03	Staphylococcus_phage	2.4e-55	99.2
AXJ80924.1\|1580827_1581151_-	hypothetical protein	A0A2I6PF12	Staphylococcus_phage	5.9e-53	100.0
AXJ80925.1\|1581229_1581391_-	hypothetical protein	A7TWM3	Staphylococcus_phage	8.6e-21	100.0
AXJ80926.1\|1581403_1581667_-	hypothetical protein	A7TWG0	Staphylococcus_phage	5.7e-46	100.0
AXJ80927.1\|1581691_1581907_-	hypothetical protein	A0A2I6PF01	Staphylococcus_phage	2.7e-30	97.2
AXJ80928.1\|1581961_1582327_+	hypothetical protein	A0A2I6PF07	Staphylococcus_phage	2.4e-63	100.0
AXJ80929.1\|1582295_1582541_-	hypothetical protein	A0A2I6PF15	Staphylococcus_phage	5.1e-41	100.0
AXJ80930.1\|1582590_1582809_-	hypothetical protein	B5WZL5	Staphylococcus_phage	7.8e-33	100.0
AXJ80931.1\|1582824_1583601_-	hypothetical protein	M1RZB2	Staphylococcus_phage	1.5e-142	100.0
AXJ80932.1\|1583626_1583854_-	hypothetical protein	B5WZL3	Staphylococcus_phage	3.3e-34	100.0
AXJ80933.1\|1584025_1584640_+	LexA repressor	B5WZL2	Staphylococcus_phage	9.0e-111	100.0
AXJ80934.1\|1584655_1585576_+	DNA polymerase III PolC-type	B5WZL1	Staphylococcus_phage	2.5e-173	100.0
AXJ80935.1\|1585672_1585855_+	hypothetical protein	A0A2I6PDR4	Staphylococcus_phage	5.3e-27	100.0
AXJ80936.1\|1585912_1586038_+	hypothetical protein	Q4ZCR4	Staphylococcus_virus	1.6e-11	97.6
AXJ80937.1\|1586034_1586649_-	hypothetical protein	A0A2I6PEZ0	Staphylococcus_phage	2.5e-105	99.5
AXJ80938.1\|1586774_1587980_+	Transposase	A0A2I6PEN0	Staphylococcus_phage	7.7e-223	100.0
AXJ80939.1\|1588022_1590050_-	hypothetical protein	B5WZK7	Staphylococcus_phage	2.0e-114	97.2
AXJ80940.1\|1590042_1590972_-	hypothetical protein	NA	NA	NA	NA
AXJ80941.1\|1591216_1592968_-	Sensor protein SrrB	A0A1V0SGX0	Hokovirus	1.7e-21	33.6
AXJ80942.1\|1592948_1593674_-	Transcriptional regulatory protein SrrA	W8CYM9	Bacillus_phage	4.6e-45	43.0

DBSCAN-SWA_6

1650130 : 1658442

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ81005.1\|1650130_1650916_-	High-affinity zinc uptake system ATP-binding protein ZnuC	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
AXJ81006.1\|1651041_1651932_-	putative endonuclease 4	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
AXJ81007.1\|1651941_1653288_-	DEAD-box ATP-dependent RNA helicase CshB	A0A1V0SIR5	Klosneuvirus	5.3e-55	33.7
AXJ81008.1\|1653401_1654502_-	Putative GTP cyclohydrolase 1 type 2	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
AXJ81009.1\|1654504_1655182_-\|tRNA	tRNA (adenine(22)-N(1))-methyltransferase	NA	NA	NA	NA
AXJ81010.1\|1655312_1656419_-	RNA polymerase sigma factor SigA	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
AXJ81011.1\|1656642_1658442_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.6e-54	36.0

DBSCAN-SWA_7

1727501 : 1736544

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ81081.1\|1727501_1728020_-	Adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
AXJ81082.1\|1728041_1730315_-	Single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-62	28.8
AXJ81083.1\|1730517_1732797_-	bifunctional preprotein translocase subunit SecD/SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
AXJ81084.1\|1733071_1733332_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
AXJ81085.1\|1733350_1734490_-\|tRNA	Queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
AXJ81086.1\|1734512_1735538_-\|tRNA	S-adenosylmethionine:tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
AXJ81087.1\|1735539_1736544_-	Holliday junction ATP-dependent DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_8

1862215 : 1944791

Staphylococcus_phage(93.55%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ81190.1\|1862215_1868776_-	Extracellular matrix-binding protein ebh precursor	A0A2H4PQU6	Staphylococcus_phage	2.0e-304	98.1
AXJ81191.1\|1869101_1869413_-	molybdopterin biosynthesis-like protein MoeZ	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
AXJ81192.1\|1869434_1871852_-\|tRNA	Leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.1
AXJ81193.1\|1872139_1873321_-	Multidrug resistance protein MdtH	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
AXJ81194.1\|1873430_1874384_+	coproporphyrinogen III oxidase	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
AXJ81195.1\|1874380_1874944_+	16S rRNA m(4)C1402 methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
AXJ81196.1\|1875063_1875465_-	HTH-type transcriptional regulator rot	NA	NA	NA	NA
AXJ81197.1\|1877043_1877871_-	Phospholipase YtpA	NA	NA	NA	NA
AXJ81198.1\|1878104_1879106_+	Proline dehydrogenase 1	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
AXJ81199.1\|1879227_1879692_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
AXJ81200.1\|1879704_1880886_-	Riboflavin biosynthesis protein RibBA	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
AXJ81201.1\|1880896_1881529_-	Riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
AXJ81202.1\|1881535_1882567_-	Riboflavin biosynthesis protein RibD	A0A2H4PQS8	Staphylococcus_phage	4.8e-197	99.4
AXJ81203.1\|1883059_1884562_-	hypothetical protein	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
AXJ81204.1\|1885084_1885399_+	Transcriptional repressor SdpR	A0A2H4PQT4	Staphylococcus_phage	2.0e-53	100.0
AXJ81205.1\|1885398_1886691_+	Arsenical pump membrane protein	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
AXJ81206.1\|1886708_1887104_+	Arsenate-mycothiol transferase ArsC2	A0A2H4PQT9	Staphylococcus_phage	6.3e-73	100.0
AXJ81207.1\|1887398_1888253_-	Bifunctional autolysin precursor	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
AXJ81208.1\|1888528_1888753_-	hypothetical protein	NA	NA	NA	NA
AXJ81209.1\|1888951_1889422_+	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
AXJ81210.1\|1889534_1889978_+	hypothetical protein	NA	NA	NA	NA
AXJ81211.1\|1889964_1890408_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	3.0e-55	85.0
AXJ81212.1\|1890703_1891339_+\|protease	CAAX amino terminal protease self- immunity	NA	NA	NA	NA
AXJ81213.1\|1891778_1892492_-	Transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
AXJ81214.1\|1892751_1893054_+	hypothetical protein	NA	NA	NA	NA
AXJ81215.1\|1893309_1893675_+	Putative fluoride ion transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
AXJ81216.1\|1893671_1894025_+	Putative fluoride ion transporter CrcB	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
AXJ81217.1\|1896107_1896941_-	Glyoxal reductase	A0A2H4PQR8	Staphylococcus_phage	9.6e-156	98.6
AXJ81218.1\|1897152_1898061_-	hypothetical protein	A0A2H4PQQ8	Staphylococcus_phage	3.2e-136	98.7
AXJ81219.1\|1898185_1899379_-	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
AXJ81220.1\|1899749_1901342_+	Phosphoenolpyruvate carboxykinase [ATP]	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
AXJ81221.1\|1901477_1901963_-	Transposase IS200 like protein	A0A1P8BMC0	Lactococcus_phage	4.9e-19	35.4
AXJ81222.1\|1902274_1902997_-	Alpha/beta hydrolase family protein	A0A2H4PQM6	Staphylococcus_phage	2.1e-122	98.1
AXJ81223.1\|1902977_1903457_-	Putative 8-oxo-dGTP diphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	1.5e-84	98.7
AXJ81224.1\|1903516_1903774_+	Putative membrane protein insertion efficiency factor	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
AXJ81225.1\|1903770_1904772_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	4.8e-186	97.6
AXJ81226.1\|1904776_1906255_-	2-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.0e-281	97.0
AXJ81227.1\|1906413_1906896_-	hypothetical protein	A0A2H4PQN7	Staphylococcus_phage	2.5e-79	98.6
AXJ81228.1\|1907207_1907624_+	hypothetical protein	A0A2H4PQM8	Staphylococcus_phage	5.2e-09	90.4
AXJ81229.1\|1907902_1908898_+	Telomeric repeat-binding factor 2	A0A2H4PQN2	Staphylococcus_phage	7.1e-73	96.4
AXJ81230.1\|1908973_1909600_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	7.1e-79	82.7
AXJ81231.1\|1909640_1909985_+	hypothetical protein	A0A2H4PQN6	Staphylococcus_phage	6.3e-53	92.0
AXJ81232.1\|1910082_1910634_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.0e-20	94.1
AXJ81233.1\|1910851_1911493_-	hypothetical protein	A0A2H4PQN8	Staphylococcus_phage	2.6e-76	93.2
AXJ81234.1\|1911793_1911970_-	hypothetical protein	NA	NA	NA	NA
AXJ81235.1\|1911980_1912364_-	hypothetical protein	NA	NA	NA	NA
AXJ81236.1\|1912967_1913111_-	Transposase	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0
AXJ81237.1\|1913980_1914358_-	hypothetical protein	NA	NA	NA	NA
AXJ81238.1\|1914878_1915439_-	hypothetical protein	A0A2H4PQT3	Staphylococcus_phage	9.5e-75	100.0
AXJ81239.1\|1915755_1916928_-	Transposase, Mutator family	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
AXJ81240.1\|1921046_1922246_-	EcoKI restriction-modification system protein HsdS	A0A2H4PQP5	Staphylococcus_phage	5.5e-229	99.7
AXJ81241.1\|1922238_1923795_-	Type I restriction enzyme EcoKI M protein	A0A2H4PQP4	Staphylococcus_phage	2.3e-288	99.4
AXJ81242.1\|1924157_1924877_-\|protease	Serine protease SplF precursor	A0A2H4PQP1	Staphylococcus_phage	1.1e-131	100.0
AXJ81243.1\|1925027_1925744_-\|protease	Serine protease SplE precursor	A0A2H4PQN5	Staphylococcus_phage	1.1e-131	100.0
AXJ81244.1\|1925901_1926621_-\|protease	Serine protease SplD precursor	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
AXJ81245.1\|1926741_1927461_-\|protease	Serine protease SplC precursor	A0A2H4PQP7	Staphylococcus_phage	1.2e-130	99.2
AXJ81246.1\|1927518_1928241_-\|protease	Serine protease SplB precursor	A0A2H4PQN0	Staphylococcus_phage	2.4e-131	99.6
AXJ81247.1\|1928365_1929082_-\|protease	Serine protease SplA precursor	A0A2H4PQN3	Staphylococcus_phage	2.0e-125	96.2
AXJ81248.1\|1930045_1930612_+	hypothetical protein	A0A2H4PQH6	Staphylococcus_phage	3.3e-99	100.0
AXJ81249.1\|1931085_1931784_-	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	3.8e-113	94.4
AXJ81250.1\|1931780_1932542_-	ABC-2 family transporter protein	A0A2H4PQH2	Staphylococcus_phage	4.4e-131	100.0
AXJ81251.1\|1932538_1933231_-	putative ABC transporter ATP-binding protein YxlF	A0A2H4PQG7	Staphylococcus_phage	6.2e-124	100.0
AXJ81252.1\|1933253_1934627_-	Thermophilic serine proteinase precursor	A0A2H4PQH1	Staphylococcus_phage	2.9e-258	100.0
AXJ81253.1\|1934636_1935155_-	Epidermin decarboxylase	A0A2H4PQG9	Staphylococcus_phage	2.0e-95	100.0
AXJ81254.1\|1935170_1936415_-	Nisin biosynthesis protein NisC	A0A2H4PQH9	Staphylococcus_phage	2.6e-237	99.8
AXJ81255.1\|1936407_1939401_-	hypothetical protein	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	97.3
AXJ81256.1\|1939465_1939609_-	Lantibiotic gallidermin precursor	A0A2H4PQH4	Staphylococcus_phage	5.3e-14	80.9
AXJ81257.1\|1940730_1941714_-	Leucotoxin LukDv precursor	A0A2H4PQH7	Staphylococcus_phage	6.8e-185	98.8
AXJ81258.1\|1941715_1942651_-	Leucotoxin LukEv precursor	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0
AXJ81259.1\|1943534_1943990_+	hypothetical protein	Q4ZCB9	Staphylococcus_virus	1.7e-61	76.8
AXJ81260.1\|1944002_1944791_+	hypothetical protein	A0A2H4PQI0	Staphylococcus_phage	5.3e-140	95.8

DBSCAN-SWA_9

1973314 : 2052394

Staphylococcus_phage(86.76%)

head,terminase,protease,tRNA,capsid,tail,lysis,holin,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ81285.1\|1973314_1973785_-\|tRNA	tRNA (cytidine(34)-2'-O)-methyltransferase	NA	NA	NA	NA
AXJ81286.1\|1973789_1974917_-	Epoxyqueuosine reductase	NA	NA	NA	NA
AXJ81287.1\|1975067_1975796_-	L-cystine import ATP-binding protein TcyC	G9BWD6	Planktothrix_phage	1.0e-36	42.7
AXJ81288.1\|1975782_1977240_-	Arginine transport system permease protein ArtQ	NA	NA	NA	NA
AXJ81289.1\|1977497_1978559_-	Phosphotransferase system, EIIC	NA	NA	NA	NA
AXJ81290.1\|1979051_1980371_+	Transposase	A0A1S5SBP9	Streptococcus_phage	1.7e-50	33.5
AXJ81291.1\|1988827_1989274_-	Peroxide-responsive repressor PerR	NA	NA	NA	NA
AXJ81292.1\|1989370_1990330_-	Glyoxylate/hydroxypyruvate reductase B	NA	NA	NA	NA
AXJ81293.1\|1990326_1990782_-	Putative peroxiredoxin bcp	NA	NA	NA	NA
AXJ81294.1\|1990862_1992152_+	Glutamate-1-semialdehyde 2,1-aminomutase 2	NA	NA	NA	NA
AXJ81295.1\|1992393_1993539_+	Fusaric acid resistance protein family protein	NA	NA	NA	NA
AXJ81296.1\|1993729_1995466_-	Putative multidrug export ATP-binding/permease protein	W8CYL7	Bacillus_phage	1.7e-53	30.4
AXJ81297.1\|1995756_1996299_-	hypothetical protein	NA	NA	NA	NA
AXJ81298.1\|1996600_1997638_-	putative A/G-specific adenine glycosylase YfhQ	NA	NA	NA	NA
AXJ81299.1\|1997789_1998767_+	hypothetical protein	NA	NA	NA	NA
AXJ81300.1\|1999027_1999864_-	hypothetical protein	NA	NA	NA	NA
AXJ81301.1\|1999872_2001390_-	Teichoic acids export ATP-binding protein TagH	NA	NA	NA	NA
AXJ81302.1\|2001404_2001719_-	hypothetical protein	NA	NA	NA	NA
AXJ81303.1\|2001696_2002515_-	Regulatory protein RecX	NA	NA	NA	NA
AXJ81304.1\|2002775_2003585_-	Monofunctional glycosyltransferase	NA	NA	NA	NA
AXJ81305.1\|2003925_2004441_-\|protease	Putative cysteine protease YraA	NA	NA	NA	NA
AXJ81306.1\|2004571_2004733_-	hypothetical protein	NA	NA	NA	NA
AXJ81307.1\|2005205_2005889_-	hypothetical protein	A0A0A7S0U2	Clostridium_phage	1.1e-13	28.3
AXJ81308.1\|2005885_2006209_-	hypothetical protein	NA	NA	NA	NA
AXJ81309.1\|2006165_2007215_-	hypothetical protein	NA	NA	NA	NA
AXJ81310.1\|2007833_2009288_-	putative cell wall hydrolase LytN precursor	I1W626	Staphylococcus_phage	4.1e-287	99.0
AXJ81311.1\|2009298_2009601_-\|holin,lysis	Phage lysis protein, holin	A0A2I6PF56	Staphylococcus_phage	3.1e-48	100.0
AXJ81312.1\|2009736_2010036_-	hypothetical protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
AXJ81313.1\|2010081_2010246_-	hypothetical protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
AXJ81314.1\|2010238_2010628_-	hypothetical protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
AXJ81315.1\|2010627_2012094_-	hypothetical protein	A0A2I6PDE3	Staphylococcus_phage	2.0e-257	94.3
AXJ81316.1\|2012093_2014004_-	hypothetical protein	A0A2I6PEQ9	Staphylococcus_phage	0.0e+00	100.0
AXJ81317.1\|2014019_2014310_-	hypothetical protein	U5U457	Staphylococcus_phage	2.1e-49	100.0
AXJ81318.1\|2014309_2015893_-\|tail	Prophage endopeptidase tail	A0A2I6PEQ5	Staphylococcus_phage	9.3e-309	100.0
AXJ81319.1\|2015901_2016726_-\|tail	Phage tail protein	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
AXJ81320.1\|2016725_2022926_-	Glycyl-glycine endopeptidase ALE-1 precursor	U5U762	Staphylococcus_phage	0.0e+00	99.8
AXJ81321.1\|2022939_2023098_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
AXJ81322.1\|2023139_2023490_-	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
AXJ81323.1\|2023547_2024003_-	Bacterial Ig-like domain (group 2)	A0A2I6PER6	Staphylococcus_phage	5.7e-78	100.0
AXJ81324.1\|2024094_2024736_-\|tail	Phage major tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
AXJ81325.1\|2024770_2025166_-	hypothetical protein	A0A2I6PDD8	Staphylococcus_phage	2.6e-66	100.0
AXJ81326.1\|2025166_2025568_-	hypothetical protein	A0A2I6PDD3	Staphylococcus_phage	6.2e-68	100.0
AXJ81327.1\|2025564_2025897_-	hypothetical protein	A0A2I6PDD6	Staphylococcus_phage	6.2e-58	100.0
AXJ81328.1\|2025908_2026187_-\|head,tail	Phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
AXJ81329.1\|2026255_2027419_-\|capsid	Phage capsid family protein	A0A2I6PDD7	Staphylococcus_phage	9.4e-218	100.0
AXJ81330.1\|2027430_2028204_-\|protease	ATP-dependent Clp protease proteolytic subunit 1	M1TAZ4	Staphylococcus_phage	2.7e-136	99.6
AXJ81331.1\|2028187_2029426_-\|portal	Phage portal protein	A0A2K9VBP0	Staphylococcus_phage	6.9e-235	100.0
AXJ81332.1\|2029430_2031122_-	Phage Terminase	A0A2I6PE44	Staphylococcus_phage	0.0e+00	99.6
AXJ81333.1\|2031111_2031417_-\|terminase	Phage terminase, small subunit	A0A2I6PE27	Staphylococcus_phage	2.9e-49	100.0
AXJ81334.1\|2031545_2031860_-	HNH endonuclease	Q4ZCU3	Staphylococcus_virus	2.5e-56	100.0
AXJ81335.1\|2032016_2032454_-	hypothetical protein	A0A2I6PEB8	Staphylococcus_phage	1.0e-76	100.0
AXJ81336.1\|2032466_2033825_-	hypothetical protein	A0A0K1LKG3	Staphylococcus_phage	1.4e-260	98.9
AXJ81337.1\|2033814_2034105_-	VRR-NUC domain protein	U5U7A3	Staphylococcus_phage	4.9e-51	100.0
AXJ81338.1\|2034445_2036893_-	Virulence-associated protein E	B5WZN5	Staphylococcus_phage	0.0e+00	99.9
AXJ81339.1\|2036945_2037146_-	hypothetical protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
AXJ81340.1\|2037213_2037369_-	Transcriptional activator RinB	B5WZN3	Staphylococcus_phage	1.2e-19	100.0
AXJ81341.1\|2037358_2037595_-	hypothetical protein	A7TWB3	Staphylococcus_phage	1.9e-37	100.0
AXJ81342.1\|2037619_2037856_-	hypothetical protein	C8CH06	Staphylococcus_phage	3.1e-35	98.7
AXJ81343.1\|2037892_2038429_-	dUTPase	S4V978	Staphylococcus_phage	1.0e-94	98.9
AXJ81344.1\|2038421_2038604_-	hypothetical protein	D2JGL7	Staphylococcus_phage	2.6e-26	100.0
AXJ81345.1\|2038593_2038848_-	hypothetical protein	W5R8J0	Staphylococcus_phage	5.0e-39	100.0
AXJ81346.1\|2038859_2039108_-	hypothetical protein	A0A0K1LL46	Staphylococcus_phage	3.0e-41	97.6
AXJ81347.1\|2039107_2039362_-	hypothetical protein	A0A2I6PDN8	Staphylococcus_phage	1.8e-41	96.4
AXJ81348.1\|2039361_2039721_-	PVL ORF-50-like family protein	D2JGL0	Staphylococcus_phage	4.5e-62	100.0
AXJ81349.1\|2039721_2039907_-	hypothetical protein	D2JGK9	Staphylococcus_phage	7.0e-27	100.0
AXJ81350.1\|2039906_2040314_-	Endodeoxyribonuclease RusA	D2JGK8	Staphylococcus_phage	1.7e-73	100.0
AXJ81351.1\|2040323_2040545_-	hypothetical protein	Q4ZBL4	Staphylococcus_phage	1.7e-35	100.0
AXJ81352.1\|2040557_2040716_-	hypothetical protein	A0A0H3U301	Staphylococcus_phage	4.5e-22	98.1
AXJ81353.1\|2040712_2041498_-	DNA replication protein DnaC	A0A0H4J332	Staphylococcus_phage	4.2e-145	99.6
AXJ81354.1\|2041510_2042242_-	hypothetical protein	A0A1J0MGB2	Staphylococcus_phage	1.2e-80	79.3
AXJ81355.1\|2042306_2042588_+	hypothetical protein	A0A1W6JPU7	Staphylococcus_phage	2.6e-49	100.0
AXJ81356.1\|2042580_2042730_-	hypothetical protein	A7TWN0	Staphylococcus_phage	2.4e-17	100.0
AXJ81357.1\|2042726_2043401_-	hypothetical protein	A1KX69	Staphylococcus_virus	1.5e-130	99.6
AXJ81358.1\|2043412_2043856_-	Single-stranded DNA-binding protein ssb	A0A2I6PD99	Staphylococcus_phage	3.2e-73	95.9
AXJ81359.1\|2043852_2044503_-	ERF superfamily protein	A0A0F6N3I5	Staphylococcus_phage	1.1e-119	100.0
AXJ81360.1\|2044503_2045040_-	Bacteriophage Mu Gam like protein	A0A2I6PD93	Staphylococcus_phage	1.7e-81	100.0
AXJ81361.1\|2045052_2045313_-	hypothetical protein	A0A059T5A3	Staphylococcus_phage	1.2e-43	100.0
AXJ81362.1\|2045558_2045780_-	hypothetical protein	A0A1X9H0Q4	Staphylococcus_phage	3.3e-31	98.6
AXJ81363.1\|2045850_2046504_+	hypothetical protein	Q4ZBF5	Staphylococcus_virus	1.3e-115	99.5
AXJ81364.1\|2046513_2046657_-	hypothetical protein	A0A0H4ITW0	Staphylococcus_phage	5.6e-16	97.9
AXJ81365.1\|2046672_2047425_-	Phage antirepressor protein KilAC domain protein	A0A0E3T9K5	Staphylococcus_phage	4.8e-138	99.2
AXJ81366.1\|2047426_2047612_-	helix-turn-helix protein	A0A0H4IP57	Staphylococcus_phage	1.3e-25	100.0
AXJ81367.1\|2048057_2048540_+	hypothetical protein	A0A0N9BAX2	Staphylococcus_phage	1.1e-82	100.0
AXJ81368.1\|2048640_2048820_-	hypothetical protein	A0A0H3U490	Staphylococcus_phage	2.2e-25	98.3
AXJ81369.1\|2048834_2049278_-	hypothetical protein	Q6R853	Staphylococcus_virus	5.8e-75	99.3
AXJ81370.1\|2049325_2049538_-	helix-turn-helix protein	A7TWF1	Staphylococcus_phage	1.6e-30	100.0
AXJ81371.1\|2049689_2050421_+	LexA repressor	S4SVC5	Staphylococcus_phage	6.9e-134	100.0
AXJ81372.1\|2050456_2051137_+	PemK-like protein	A0A2H4PQQ5	Staphylococcus_phage	5.1e-123	100.0
AXJ81373.1\|2051347_2052394_+	Tyrosine recombinase XerC	Q4ZE08	Staphylococcus_virus	4.2e-201	100.0

DBSCAN-SWA_10

2807656 : 2825181

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXJ82062.1\|2807656_2808874_-	Transposase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
AXJ82063.1\|2808955_2809159_-	Excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
AXJ82064.1\|2809619_2809850_-	Helix-turn-helix domain protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
AXJ82065.1\|2809846_2810269_-	RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
AXJ82066.1\|2810773_2811127_+	anaerobic benzoate catabolism transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	3.0e-58	99.1
AXJ82067.1\|2811472_2813392_-	Tetracycline resistance protein TetM from transposon TnFO1	A0A1S5SF82	Streptococcus_phage	0.0e+00	99.4
AXJ82068.1\|2813768_2814704_-	Conjugative transposon protein TcpC	A0A1S5SF22	Streptococcus_phage	5.9e-170	99.4
AXJ82069.1\|2814700_2815657_-	putative endopeptidase p60 precursor	A0A1S5SEZ8	Streptococcus_phage	2.8e-183	100.0
AXJ82070.1\|2815610_2817875_-	hypothetical protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	94.3
AXJ82071.1\|2817877_2820325_-	AAA-like domain protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
AXJ82072.1\|2820789_2821287_-	Antirestriction protein (ArdA)	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
AXJ82073.1\|2821403_2821625_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
AXJ82074.1\|2821667_2822873_-	Replication initiation factor	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
AXJ82075.1\|2823050_2824436_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
AXJ82076.1\|2824464_2824848_-	hypothetical protein	A0A1S5SF96	Streptococcus_phage	2.3e-64	100.0
AXJ82077.1\|2824866_2825181_-	hypothetical protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP022906

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection