CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP033573	Acinetobacter nosocomialis strain 2010N17-248 plasmid p2010N17-248, complete sequence	0 crisprs	NA	0	0	0	0
CP033572	Acinetobacter nosocomialis strain 2010N17-248 chromosome, complete genome	2 crisprs	PD-DExK,DEDDh,csa3,WYL	0	1	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP033572_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033572_1

102734-102879

Orphan

Consensus_repeat	Method
AGTAATAAAGTTTCATACTGAAATGA	PILER-CR

2 spacers

The CRISPR arrays of CP033572_1

>merge|CP033572|1|102734-102879|PILER-CR
AGTAATAAAGTTTCATACTGATTCAGCCTTAACTTCTTGATATTTATAAACTGTAATAATTGAAGAAAAAATAAAGTTTCATACTAAAATTATTTTTTCTTCAATTTCTACTACCAGTTGAGTAATAAAGTTTCATACTGAAATGA

>CP033572|1|1|102734-102879|PILER-CR
AGTAATAAAGTTTCATACTGATTCAG	CCTTAACTTCTTGATATTTATAAACTGTAATAATTGAAGAAAAAA
TAAAGTTTCATACTAAAATTATTTTT	TCTTCAATTTCTACTACCAGTTGAGTAA
TAAAGTTTCATACTGAAATGA

Protein	Signature genes	Signature genes Name	Protein_function
CP033572.1\|AZC01583.1\|94262_94460_-\|hypothetical-protein	unknown	unknown	unknown
CP033572.1\|AZC01588.1\|104348_104810_-\|response-regulator	unknown	unknown	gnl\|CDD\|223855
CP033572.1\|AZC01576.1\|78455_79721_+\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
CP033572.1\|AZC01586.1\|103481_103694_+\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP033572.1\|AZC01579.1\|85420_86959_+\|histidine-ammonia-lyase	unknown	unknown	gnl\|CDD\|236484
CP033572.1\|AZC01589.1\|115177_116011_-\|heteromeric-transposase-endonuclease-subunit-TnsA	unknown	unknown	gnl\|CDD\|378037
CP033572.1\|AZC01587.1\|103701_104388_-\|hypothetical-protein	unknown	unknown	unknown
CP033572.1\|AZC01594.1\|120830_121280_-\|transcription-antitermination-factor-NusB	unknown	unknown	gnl\|CDD\|234686
CP033572.1\|AZC01585.1\|102909_103392_-\|hypothetical-protein	unknown	unknown	unknown
CP033572.1\|AZC01592.1\|119386_119920_-\|phosphatidylglycerophosphatase-A	unknown	unknown	gnl\|CDD\|368021
CP033572.1\|AZC01593.1\|119897_120815_-\|thiamine-phosphate-kinase	unknown	unknown	gnl\|CDD\|235583
CP033572.1\|AZC03527.1\|82006_82546_+\|HutD-family-protein	unknown	unknown	gnl\|CDD\|377578
CP033572.1\|AZC01590.1\|116162_118001_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
CP033572.1\|AZC01577.1\|81221_81974_+\|histidine-utilization-repressor	unknown	unknown	gnl\|CDD\|188194
CP033572.1\|AZC01578.1\|82684_83431_-\|IS5-like-element-ISAba31-family-transposase	unknown	unknown	gnl\|CDD\|379129
CP033572.1\|AZC01591.1\|118013_119378_-\|UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224128
CP033572.1\|AZC01582.1\|92800_93439_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319799
CP033572.1\|AZC01581.1\|88486_89692_+\|imidazolonepropionase	unknown	unknown	gnl\|CDD\|236478
CP033572.1\|AZC01584.1\|96242_97301_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375852
CP033572.1\|AZC01580.1\|87023_88436_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182566

Protein	Function_ID	Function_description	E-value
CP033572.1\|AZC01588.1\|104348_104810_-\|response-regulator	gnl\|CDD\|223855	COG0784, CheY, FOG: CheY-like receiver [Signal transduction mechanisms].	5.55327e-05
CP033572.1\|AZC01576.1\|78455_79721_+\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	1.57503e-120
CP033572.1\|AZC01586.1\|103481_103694_+\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.16678e-15
CP033572.1\|AZC01579.1\|85420_86959_+\|histidine-ammonia-lyase	gnl\|CDD\|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0
CP033572.1\|AZC01589.1\|115177_116011_-\|heteromeric-transposase-endonuclease-subunit-TnsA	gnl\|CDD\|378037	pfam08722, Tn7_Tnp_TnsA_N, TnsA endonuclease N terminal. The Tn7 transposase is composed of proteins TnsA and TnsB. DNA breakage at the 5' end of the transposon is carried out by TnsA, and breakage and joining at the 3' end is carried out by TnsB. The N terminal domain of TnsA is catalytic.	1.90412e-24
CP033572.1\|AZC01594.1\|120830_121280_-\|transcription-antitermination-factor-NusB	gnl\|CDD\|234686	PRK00202, nusB, transcription antitermination factor NusB.	3.16858e-52
CP033572.1\|AZC01592.1\|119386_119920_-\|phosphatidylglycerophosphatase-A	gnl\|CDD\|368021	pfam04608, PgpA, Phosphatidylglycerophosphatase A. This family represents a family of bacterial phosphatidylglycerophosphatases (EC:3.1.3.27), known as PgpA. It appears that bacteria possess several phosphatidylglycerophosphatases, and thus, PgpA is not essential in Escherichia coli.	5.14579e-47
CP033572.1\|AZC01593.1\|119897_120815_-\|thiamine-phosphate-kinase	gnl\|CDD\|235583	PRK05731, PRK05731, thiamine monophosphate kinase; Provisional.	1.73491e-137
CP033572.1\|AZC03527.1\|82006_82546_+\|HutD-family-protein	gnl\|CDD\|377578	pfam05962, HutD, HutD. HutD from Pseudomonas fluorescens SBW25 is a component of the histidine uptake and utilisation operon. HutD is operonic with the well characterized repressor protein HutC. Genetic analysis using transcriptional fusions (lacZ) and deletion mutants shows that hutD is necessary to maintain fitness in environments replete with histidine. Evidence outlined by Zhang & Rainey (2007) suggests that HutD functions as a governor that sets an upper bound on the level of hut operon transcription. The mechanistic basis is unknown, but in silico molecular docking studies based on the crystal structure of PA5104 (HutD from Pseudomonas aeruginosa) show that urocanate (the first breakdown product of histidine) docks with the active site of HutD.	2.30125e-49
CP033572.1\|AZC01590.1\|116162_118001_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP033572.1\|AZC01577.1\|81221_81974_+\|histidine-utilization-repressor	gnl\|CDD\|188194	TIGR02018, Histidine_utilization_repressor, histidine utilization repressor, proteobacterial. This model represents a proteobacterial histidine utilization repressor. It is usually found clustered with the enzymes HutUHIG so that it can regulate its own expression as well. A number of species have several paralogs and may fine-tune the regulation according to levels of degradation intermediates such as urocanate. This family belongs to the larger GntR family of transcriptional regulators. [Energy metabolism, Amino acids and amines, Regulatory functions, DNA interactions].	1.32448e-120
CP033572.1\|AZC01578.1\|82684_83431_-\|IS5-like-element-ISAba31-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	6.1536e-22
CP033572.1\|AZC01591.1\|118013_119378_-\|UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase	gnl\|CDD\|224128	COG1207, GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) [Cell envelope biogenesis, outer membrane].	0
CP033572.1\|AZC01582.1\|92800_93439_+\|HAD-family-hydrolase	gnl\|CDD\|319799	cd04303, HAD_PGPase, phosphoglycolate phosphatase, similar to Synechococcus elongates phosphoglycolate phosphatase PGP/CbbZ. Phosphoglycolate phosphatase catalyzes the dephosphorylation of phosphoglycolate; its activity requires divalent cations, especially Mg++. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.76846e-105
CP033572.1\|AZC01581.1\|88486_89692_+\|imidazolonepropionase	gnl\|CDD\|236478	PRK09356, PRK09356, imidazolonepropionase; Validated.	0
CP033572.1\|AZC01584.1\|96242_97301_-\|hypothetical-protein	gnl\|CDD\|375852	pfam18426, Tli4_C, Tle cognate immunity protein 4 C-terminal domain. T6SS bacteria employ toxic effectors to inhibit rival cells and concurrently use effector cognate immunity proteins to protect their sibling cells. The effector and immunity pairs (E-I pairs) endow the bacteria with a great advantage in niche competition. This is the C-terminal domain of Tli4. The Tle cognate immunity proteins (Tlis) can directly disable the transported Tle protein and thereby mediate the self-protection process. The Tle-Tli effector-immunity (E-I) pairs confer substantial advantage to the donor cell during interbacterial competition. Tli4 displays a two-domain structure, in which a large lobe and a small lobe form a crab claw-like conformation. Tli4 uses this crab claw to grasp the cap domain of Tle4, especially the lid2 region, which prevents the interfacial activation of Tle4 and thus causes enzymatic dysfunction of Tle4. Structural comparison indicates similarity between this C-terminal domain of Tli4 and Tsi3, which is the cognate immunity protein of the effector protein Tse3 in P. aeruginosa PDB:4n7s.	1.52164e-12
CP033572.1\|AZC01580.1\|87023_88436_+\|amino-acid-permease	gnl\|CDD\|182566	PRK10580, proY, putative proline-specific permease; Provisional.	0

>CP033572.1|AZC01584.1|96242_97301_-|hypothetical-protein
MNLLKRLTLCLLTAVSFSACSNVEKEQEGIKVIDYSNPKKVCFGRIELTVPKETEVEYSKFNYNGSDIEVDESVKTYEAYQKLINDKIQYLKYEPHETEGVLLKREIQGPINKDGRVVSNIIIYRSNKFTTEAYEIDGYLYFPLKGLLILKSGADNDLLDNAIEDMKQTLKSIKIRSAKGEEQAGLCWKDFFILDDMSKNIPFTGGYLHFRFPSYPRVRVDIEHRARLESDRPLIEMVKENEANAPAVFKAMMSTENLREQKKEINGLAGEEIFGYAHRRGFSERGFESAAWQYLGSVENNNDPFIHYSLESAELVHDDEPLQSTVSQKKVFQLHDFILNSIQISPNNKKEQ
>CP033572.1|AZC01583.1|94262_94460_-|hypothetical-protein
MLSSANIEHGIMLALIALVSIILLIIAGITALFRLKSKNKSETKDMIIISFALIGVTGLLFSCSG
>CP033572.1|AZC01582.1|92800_93439_+|HAD-family-hydrolase
MEKTLKQYQAIIFDLDGTLVDSFHFFLNVLNQLSAKYKFKTVSLHEVEYYKQLTPREIMKEMNVSRWKLPWIAKDFIRLMKERDEEIHLFEGMRDHLIELHKQRYTLAIITSNSKENCQNVLGEELCELFSHIDGGSSIFGKAKRIKRVLNILDVSKNHAIYVGDQTTDGEAAHKAGIDFAAVGWGYTSAEKLKTIQPKVVLTDLATMKEFF
>CP033572.1|AZC01581.1|88486_89692_+|imidazolonepropionase
MKKLWQNCHIATMQNGQYSYIEDAAIVTEGHLIHWIGKQQQLPTDTYSETVDLNGAWVTPGFIDCHTHSVFGGNRSVEFEKRLQGVSYAEIAASGGGIASTVRATREASEEQLLNSALKRIRCMQQDGVTTIEIKSGYGLNYENERKMLRVIRQIGEKLPMTVKSTCLAAHALPPEYKDQSDAYIEHICTEMLPKLHAEGLVDAVDAFCEHLAFSPAQVERVFKTAQSLGLPVKLHAEQLSSLGGSSLAARYHALSADHLEYMTEDDVKAMAESGTVAVLLPGAFYLLRETQYPPIESLIKHGVRIALSSDLNPGTSPALSVRLMLNMGSTLFRLTPEQALAGVTIHAAQALGLEQTHGSLEQGKVADFVAWDIEHPSEIVYWLGGDLPKRVVQHGQEVIF
>CP033572.1|AZC01580.1|87023_88436_+|amino-acid-permease
MSQNSTLQRGLNTRHIRFLALGSAIGTGLFYGSATAIKMAGPSVLLAYIVAGIAIYIVMRALGEMAVHNPVSGSFSHYASQYIGPLAGFTTGWTYVFEMVIVAIADVTAFGIYMGFWYPDVPRWIWILSLIMFLGAINLIHVKVFGELEFWLSIVKVSAIVAMILGGLGLMFYGFHVDHSNVVPGLQNLWIYDGFMPHGIAGLVACLSVVVFAFGGIEIIGLTAGESQDPKTTLPKAINAVPVRILLFYVLTIFVLMSIFPWNQIGSQGSPFVQIFENLGIKSAANILNIVVVTAAISAINSDVFGAGRMLYGMANRGQAPQVFKKLSRNGVPWMTVVVMAGVLLIGVVLNYLIPENVFVIIASIATFATVWVWLMILLSQVAMRRKLSTAEIKALDFPVFGWPYAPAFAIGFMVFILVMMGYFPDSRPAIYVGITWLALLTIAYRIWVKPEQSLGKESEPVQQNIEMES
>CP033572.1|AZC01579.1|85420_86959_+|histidine-ammonia-lyase
MELLIQPGKLTLADLRQAYLNPIKVKLDESASSAIDASVACVEKIVNEGRTAYGINTGFGLLASTKIAPEDLEKLQRSLVLSHAAGVGEALDDAMVRLIILLKANSLARGFSGIRRKVIDALLALINAEVYPHIPLKGSVGASGDLAPLAHMSLVLLGEGKASYKGEWLPAVEALKVAGLEPISLAAKEGLALLNGTQVSTAYALRGLFEAEDLFAAATVCGGLSVEAMLGSRAPFDARIHEVRGQRGQIDVAAAYRDLLTDSSEIAHSHEDCSKVQDPYSLRCQPQVMGACLTQIRQAAEVLEIEANAVSDNPLVFAEQGDVISGGNFHAEPVAMAADNLALAIAEIGSLSERRISMMMDRHMSQLPPFLVANGGVNSGFMIAQVTAAALASDNKALAHPASVDSLPTSANQEDHVSMAPNAGKRLWYMADNVRGILAVEWLGACQGLDFREGLKSSPKLEQARKILRDQVPYYSEDRFFAPDIEQASELLASGCLNKLLIPKLLPSLSEV
>CP033572.1|AZC01578.1|82684_83431_-|IS5-like-element-ISAba31-family-transposase
MPRTMLTDQHWQKLKVILRNLSIHHNSNLRNFIEAILYRIRTGCPWRDIPCCFGHSNSIFKRFNRWSSSGKFLRLFKLLASCPDMEWIFIDGSHVRAHQHSAGIANQSISKSVGGNSSKIHLIVDAHGNPIDFMITDGTTHDVKVAPDLISTLDLKETKVVCADKGYDSEPLREQIRKTGTKANIPKKTNSQSNNDHMDWYLYKIRHLVENMFCRLKQFRGIATRYDKLKRNYQSSVALACIFLWLPL
>CP033572.1|AZC03527.1|82006_82546_+|HutD-family-protein
MLWKNGAGFTLEIARSQGEADFDWRISMADVTTSGPFSFFPNKQRIISVLDGQGIVLHVDELPAKMLNQGDIFAFHGESQVQSELLEGAIRDLNLIYDPAKFHARFQWLNDAAEQAFISSADLIFIFNQGSETQVNVHDHSVQIAAHETLKIEKKSGVTSINFPKKQLKSCYVIELIQL
>CP033572.1|AZC01577.1|81221_81974_+|histidine-utilization-repressor
MPRTSKQEHTELSIEADSPVPLYQRVKQLISQKIYEGSWAVNKKIPSESELVNQLGCSRMTVNRALRELTTEGLLVRIQGVGSFVAEGQGRTALFQINNIADEIIARNHKHHAEVLVLEQIYANAEQSVLMQTREGQRLFHSIIVHYENDVPVQVEDRLVDAALIPDYLEQDFKTITPNAYLMAKAPVTEGEHIVEAVLASAQECKWLKITKAEPCLLIRRRTWSNKQLISSARLIYPGSRYYLEGKFNP
>CP033572.1|AZC01576.1|78455_79721_+|GTP-binding-protein
MISLNIIQRDQAMHTAIANSFAKLPVTVLSGFLGAGKTTLLNHILNNREGRRIAVIVNDMSEVNIDAALVREGGAELSRTDEKLVEMSNGCICCTLREDLLVEVRRLADEGRFDQLVIESTGISEPLPVAETFTFEDEDGNSLNEFARLDTMVTVVDAFNFLKDYSSVDSLQQRGESLGEQDERTVVDLLIDQIEFCDVIVLNKIDLIDQAQQDQLIAILKTLNPRARIEIAQFGKIALDKILNTQLFDFDEAAQAPGWLKELRGEHTPETEEYGISSFVYRARRPFHPERFYDLVQSEWPGVVRSKGFFWLAADPTLAYSWSQAGAMARHSLAGYWWAAVSEEDWPSDLNSIEQIKKNWDARTGDARQELVLIGMQMDEQALIQRLERCLLNDEEMALGPQAWQNWSNPFKQDDETMLIA
>CP033572.1|AZC01585.1|102909_103392_-|hypothetical-protein
MKQIASPIFQSFLLLLSHNQIDGWTSNKIWNNLNLSKDEKERINQQQLYRLLRKLVKQGYLAKNIHHDNSRLSTFVETESMNDFRKQFENHAVIHDLEKLELKTKELKEKQKICESQINASELALIDFPELKSEILRRKNQLLQDIEKMKAYTDFLASLI
>CP033572.1|AZC01586.1|103481_103694_+|XRE-family-transcriptional-regulator
MFMSELTIQFGQLVRKYRKERNMSQEQLALLCNMDRSYLGRIERGEVNPTLEKIYEVANTLNISPTLLLP
>CP033572.1|AZC01587.1|103701_104388_-|hypothetical-protein
MSEIFSETVLPELEIWKDYASRQIHTKQTEKALLRLVVNHLNHLLEEDEIPSYPEEFYIYPIKDKILRTGTLIKSKINDYYFISLSPACDLAQRNGTCKTDRLLIAEIEPIQHIKDIVYRQFSTQTAGTKKDQNISKELKKYFSNNYSNYYHSLPKIKNFAGGFINFRKAQSLTQKNLDSDYEVVNIQVAAPFIKDILSRFSSYYARQGQPVIFFDTHIEEIISSNQV
>CP033572.1|AZC01588.1|104348_104810_-|response-regulator
METIKILFVEDNETPIRTFENELKDFNDESTDLKIEAIIKKTYGEAIQAIDKSFDAIIMDLALGQDQDAGNKIVKELESLGLRIPILFVSGNHSNVSPNPLIINIRARDNGDYEQDFNNIVNIYNTGLTNILGGRGEIEKNCLKYLVKQFSLN
>CP033572.1|AZC01589.1|115177_116011_-|heteromeric-transposase-endonuclease-subunit-TnsA
MANFKNTQNHELKIQKWIKEGRGQGFGNSYKPWLTIRDVSSEVRSHRVFGHKSQRTHHLLSDLELSTFLLLEWHSTTIDIREQYPLDLEQTLEIAKTIRIPHPRFGKHYQIMTSDFLVDTHNSITPKFVVQVKYSNALNDPRTIEKIEIERQYWKQQNIPFYIFTEHQVPKTVSQNIQWLYSSINTMELSEQDTLDKLNFYSDIFIKHKSKKINELARIIDQKYHFELGQSLREIRDLLAQRYFIFDLNISFKDLNTDHIQLGELNIWNEVLHAENQ
>CP033572.1|AZC01590.1|116162_118001_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGGVAERCVTEILIEGLKRLEYRGYDSAGVAVLNNEEVLRERRVGKVINLADAVADQQLTGVVGIAHTRWATHGKPTENNAHPHMSGKVAVVHNGIIENYQELKDDLQALGYVFTSQTDTEVVAHLVAEALKSTDSLLEAVQSVVPQLKGAYALGIIHSDYPDELITVREGSPLVIGVGIGENFISSDQLALLPVTNRFMYLEEGDIARLTRTSIEVFANGELVERPVKELDATVSNASKGEYKHYMLKEIYEQPEAIKQTISQALDGNSLREDFLQNAEADFSKVQSVQIIACGTSYHSGMIAKYWFEQLIGVPCQVEIASEFRYRTPVIVENTLYICISQSGETADTLAALRETQKRAKANNIDIQTLTICNVATSSMVRETDHHLLTLAGPEIGVASTKAFTTQLAALMLLVLKIGQVKQRISNVMIEEIARELWHSPKVILDTLKNDAEILRLSELFVEKQHCLFLGRGTHYPIALEGALKLKEISYIHAEGYAAGELKHGPLALVDTEMPIVILAPNDEMLDKLKSNMEEVQARGGELFVFADENSGISEKDRQHVVHIPAVNEWLAPIVYSVPVQLLSYHVAVLRGTDVDQPRNLAKSVTVE
>CP033572.1|AZC01591.1|118013_119378_-|UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase
MSTTVIILAAGKGTRMRSQLPKVLQPLAGRPLLGHVIKTAKQLLAENIITIYGHGGDHVKQTFAQENIQWVEQAEQLGTGHAVQMTLPVLPKDGISLILYGDVPLVRQTTLEQLVEVSSKTGIGMITLHVDNPTGYGRIVRQDGKIQAIVEHKDATDAQRQIQEINTGIYCVSNAKLHEWLPKLSNENAQGEYYLTDIVAMAVADGLEIASIQPELAFEVEGVNDRLQLAALERDFQQQQAKELMQQGVTFADPARFDLRGSVKVGHDVRIDVNVIIEGDCELGDFVEIGAGCILKNTKIAAGTKVQPYSVFDGAIVGENTQIGPFARLRPGAKLANEVHIGNFVEVKNTTIGLGSKANHFTYLGDAEIGADSNIGAGTITCNYDGANKHKTTIGDAVFIGSNSSLVAPVTIGNGATVGAGSVITKDVAEQSLSFERAQQISKANYQRPQKREK
>CP033572.1|AZC01592.1|119386_119920_-|phosphatidylglycerophosphatase-A
MDTNTLHKPPIHFKNMSWFNRCIVFCGVGFGSGLAPKAPGTFGSAFALLFIPIWLSLGFTLSLIAILIMSLVGIYICDQTAKVLDVHDDGRIVWDEFAGQSITLLPLIFFNIMSLQWALIGFCLFRLFDVWKPWPIRVADQKVAGGFGIMLDDIIAGLWAALCIIIFITFWGVTPFK
>CP033572.1|AZC01593.1|119897_120815_-|thiamine-phosphate-kinase
MAEFSIIDQYFNRQSNSDVALGIGDDSALITPPPNQQLVICADTLVAGRHFPLETSPHAIGWKSVAVNLSDIAAMGAKPHSILLAISLPQVDHEWLKGFSQGIYDCCNQFGVALIGGDTTQGPHLTITVTAMGWIETGKAVLRSGAKVGDYVCVSGQVGDAAYGLQHLGHPLQQRLDYPTPRCQLGQELKGLASSMIDVSDGLAQDLGHILKASKVGARLVLEKLPVDPVLQQLEEQQRWQYALAGGDDYELCFTITPQNYEKLLQKQLDVKITMIGQIVEQTKLTFEHLGSDYPLQIHGYQHFA
>CP033572.1|AZC01594.1|120830_121280_-|transcription-antitermination-factor-NusB
MSQTLQAAYAAKRKARRFAVQGIYEWQMSHNPVHEIEARTRAENAMHKVDLSYYHELLTQVIAQHEDLDALLIPVLDREIDALDGVELATLRLGAYELRDHLEIPYRVVLDEAIELAKHFGGADSHKYINGVLDRLSSTLRSAEKQQAN

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Crispr_ID: CP033572_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033572_2

2043743-2043843

Orphan

Consensus_repeat	Method
TGCGAAGCTTCAGTCGCTTCTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP033572_2

>merge|CP033572|2|2043743-2043843|CRISPRCasFinder
TGCGAAGCTTCAGTCGCTTCTCAGAACAAAGCGTTGCTTTGATTCACCCTCTTAACTCGAGCATAGTTCTCGTCTTCTTGCGAAGCTTTAGTCGCTTCTCA

>CP033572|2|1|2043743-2043843|CRISPRCasFinder
TGCGAAGCTTCAGTCGCTTCTCA	GAACAAAGCGTTGCTTTGATTCACCCTCTTAACTCGAGCATAGTTCTCGTCTTCT
TGCGAAGCTTTAGTCGCTTCTCA

Protein	Signature genes	Signature genes Name	Protein_function
CP033572.1\|AZC02573.1\|2060639_2061731_-\|chorismate-synthase	unknown	unknown	gnl\|CDD\|235438
CP033572.1\|AZC02568.1\|2046414_2047686_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
CP033572.1\|AZC02556.1\|2024348_2024669_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|376852
CP033572.1\|AZC02558.1\|2031246_2032245_-\|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|224331
CP033572.1\|AZC02561.1\|2035419_2035665_-\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|224069
CP033572.1\|AZC02569.1\|2049800_2050586_-\|acetoin-reductase	unknown	unknown	gnl\|CDD\|187624
CP033572.1\|AZC02565.1\|2043862_2044057_-\|hypothetical-protein	unknown	unknown	unknown
CP033572.1\|AZC02557.1\|2026271_2027491_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
CP033572.1\|AZC02566.1\|2044128_2044581_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223523
CP033572.1\|AZC02567.1\|2044553_2045447_-\|TIGR01244-family-phosphatase	unknown	unknown	gnl\|CDD\|350353
CP033572.1\|AZC02571.1\|2055913_2056900_+\|lipoyl-synthase	unknown	unknown	gnl\|CDD\|237261
CP033572.1\|AZC02562.1\|2035685_2037419_-\|fumarate-reductase/succinate-dehydrogenase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|181346
CP033572.1\|AZC02564.1\|2039798_2040653_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|227311
CP033572.1\|AZC02559.1\|2032241_2033081_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213260
CP033572.1\|AZC02560.1\|2033082_2033937_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
CP033572.1\|AZC02572.1\|2059314_2060544_+\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
CP033572.1\|AZC02570.1\|2052027_2053554_-\|diaminohydroxyphosphoribosylaminopyrimidine-deaminase	unknown	unknown	gnl\|CDD\|237001
CP033572.1\|AZC02574.1\|2061743_2062748_-\|50S-ribosomal-protein-L3-N(5)-glutamine-methyltransferase	unknown	unknown	gnl\|CDD\|236988
CP033572.1\|AZC02555.1\|2021316_2021736_+\|hypothetical-protein	unknown	unknown	unknown
CP033572.1\|AZC02563.1\|2037447_2038191_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099

Protein	Function_ID	Function_description	E-value
CP033572.1\|AZC02573.1\|2060639_2061731_-\|chorismate-synthase	gnl\|CDD\|235438	PRK05382, PRK05382, chorismate synthase; Validated.	0
CP033572.1\|AZC02568.1\|2046414_2047686_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	3.09672e-123
CP033572.1\|AZC02556.1\|2024348_2024669_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	5.51098e-07
CP033572.1\|AZC02558.1\|2031246_2032245_-\|HEAT-repeat-domain-containing-protein	gnl\|CDD\|224331	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion].	2.88618e-19
CP033572.1\|AZC02561.1\|2035419_2035665_-\|ferredoxin-family-protein	gnl\|CDD\|224069	COG1146, COG1146, Ferredoxin [Energy production and conversion].	7.37382e-10
CP033572.1\|AZC02569.1\|2049800_2050586_-\|acetoin-reductase	gnl\|CDD\|187624	cd05366, meso-BDH-like_SDR_c, meso-2,3-butanediol dehydrogenase-like, classical (c) SDRs. 2,3-butanediol dehydrogenases (BDHs) catalyze the NAD+ dependent conversion of 2,3-butanediol to acetonin; BDHs are classified into types according to their stereospecificity as to substrates and products. Included in this subgroup are Klebsiella pneumonia meso-BDH which catalyzes meso-2,3-butanediol to D(-)-acetonin, and Corynebacterium glutamicum L-BDH which catalyzes lX+)-2,3-butanediol to L(+)-acetonin. This subgroup is comprised of classical SDRs with the characteristic catalytic triad and NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	9.15145e-115
CP033572.1\|AZC02557.1\|2026271_2027491_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	3.08538e-100
CP033572.1\|AZC02566.1\|2044128_2044581_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|223523	COG0446, HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only].	2.65296e-11
CP033572.1\|AZC02567.1\|2044553_2045447_-\|TIGR01244-family-phosphatase	gnl\|CDD\|350353	cd14503, PTP-bact, bacterial tyrosine-protein phosphataseS similar to Neisseria NMA1982. This subfamily is composed of bacterial tyrosine-protein phosphatases similar to Neisseria meningitidis NMA1982, which displays phosphatase activity but whose biological function is still unknown.	9.21247e-30
CP033572.1\|AZC02571.1\|2055913_2056900_+\|lipoyl-synthase	gnl\|CDD\|237261	PRK12928, PRK12928, lipoyl synthase; Provisional.	0
CP033572.1\|AZC02562.1\|2035685_2037419_-\|fumarate-reductase/succinate-dehydrogenase-flavoprotein-subunit	gnl\|CDD\|181346	PRK08275, PRK08275, putative oxidoreductase; Provisional.	0
CP033572.1\|AZC02564.1\|2039798_2040653_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|227311	COG4977, COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription].	9.4039e-35
CP033572.1\|AZC02559.1\|2032241_2033081_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213260	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters. NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	1.00302e-123
CP033572.1\|AZC02560.1\|2033082_2033937_-\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	4.69013e-62
CP033572.1\|AZC02572.1\|2059314_2060544_+\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	2.11854e-61
CP033572.1\|AZC02570.1\|2052027_2053554_-\|diaminohydroxyphosphoribosylaminopyrimidine-deaminase	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	1.31786e-112
CP033572.1\|AZC02574.1\|2061743_2062748_-\|50S-ribosomal-protein-L3-N(5)-glutamine-methyltransferase	gnl\|CDD\|236988	PRK11805, PRK11805, 50S ribosomal protein L3 N(5)-glutamine methyltransferase.	1.61632e-176
CP033572.1\|AZC02563.1\|2037447_2038191_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	6.68632e-76

>CP033572.1|AZC02564.1|2039798_2040653_-|helix-turn-helix-domain-containing-protein
MAYQTLEQLQQSKAKLHETVVLDENMQLAFWSNQQDRVSVCSDHHTLSLYIQDGYESYQKTPAGWKNGGGPGRFCLLPEHQESTWDIRGGLKFVHLYYTDQHLRDVAEKIWDKEPNQIELNEVVFNDDERIRALYQFFLLDCDWQDSSNHLQMSTTASLLLNHLIRRYSSVQWQQPIIKGGLAPHKLKYIQEWIEDHLDQALTLSDLANVVNLSEYHFAHMFKQSMNMAPHQYVMQRRLTKAKGLIQSSQLSLQDIALVCGFSSASHLSHRFKQFYGMSPSQLR
>CP033572.1|AZC02563.1|2037447_2038191_-|GntR-family-transcriptional-regulator
MSQLPPDAKNHKPLYDQLRELILNKIVNGEYAVLSQIPSENEFAEQFGVSRITVRQALNQLQLEGYIFKVPGKGTFVSKPKTFQNISSLQGFAEAMSSAGHEILNRVISAELRQVPMHVVPKLKLPVKANVYEIQRVRLLNRQPVSYELTYLPEHIGLKLKEKAIDLRTTDIFKALEQECDIPLGHADLSIDATVADEELAALLQVEIGTPVLRVERLTHDANGQPIDYEYLYFSGDTFQYRLRIHR
>CP033572.1|AZC02562.1|2035685_2037419_-|fumarate-reductase/succinate-dehydrogenase-flavoprotein-subunit
METKYLEFDIVVIGGGTAGPMAAIKAKQENPNLKVLLIEKANVKRSGAISMGMDGLNNAVIPGYATPEQYTKEITIANDGVVNQSTVYAYAKHSFTTIQQLDQWGIKFEKDETGEFAVKKVHHMGAYVLPMPEGHDVKKVLYRQLKRAQVKINNRIVTTKLLKNEQGAINGVLGFDCRSGDFYVIKTKAAILCCGAAGRLGLPASGYLMGTYENPTNAGDGYAMAYHAGAELANLECFQINPLIKDYNGPACAYVTGPLGGYTANSKGERFIECDYWSGQMMWEFYQELESGNGPVYLKVDHLAEETIQTIEEILHTNERPSRGRFHEGRGTNYRQDMVEMHISEIGFCSGHSASGVWVNEKAETSVKGLYSAGDMAAVPHNYMLGAFTYGWFAGVNAAQYVSAVQDSKLNQSEIEVEKARIFAPLNCSEGLPPEQVEYKLRRFVNDYLQPPKTRQKMEIGLKRFEEIKQDIKRISARNPHELMRAAEVSFIRDCAEMAARASLFREESRWGLYHYRADFPQKNNSDWFCHAHLKKDEQGNMVSFKRPIEPYVVPINQDEAVSYDRLRIQKDVALAD
>CP033572.1|AZC02561.1|2035419_2035665_-|ferredoxin-family-protein
MTFIFKEVQHRTVAPVIIDEDKCIADKGCTVCVDVCPMDLLAIDPTTQKAYMQFDECWYCMPCEKDCPTDAVKVNIPYLLK
>CP033572.1|AZC02560.1|2033082_2033937_-|ABC-transporter-permease
MSSLAQTKPNNQITFLIKFFRQLRSYPARLKSYVIAFTSIAFWIAIWQGLAQFKVNLGFVNFSNVPTPLDVIHALWAFFQLSAAFEHVESSVFRVVIGFVLAALIGVGIGLLAGRYQKLAAFLMPPLEVLRPIPAVAWIPLAILIFPSSEASMIFITFIGALFPILLNTVHGVGAVDPRLVASAKSLGASDLAIIHEVIIPGALPNIITGLSIGMGTCWFCLVTAEMISGQHGIGYFTWESFTLQNYSNIVVGMVLIGALGMFSSTLVRVIGNRFTPWYQLRKS
>CP033572.1|AZC02559.1|2032241_2033081_-|ABC-transporter-ATP-binding-protein
MSITQGHVRIQNLSLHLGQAKNRFQALDRINFEIQPGEFICLLGPSGCGKSTLLGALAGHLPISSGSLTVDDESIFEPHPDRGLVFQQHTLFPWKSVLENIAFGLKMKGIAKQKRIEQAQKMIDLVGLKGFEHKFPAELSGGMQQRVEIARVLINQPRILLMDEPFGALDAQTRLKMQMLLLEIWQEIQTSVLFITHDIDEALFLADRVLIMSHRPGRIIEEIPLKFERPRDVELVTSSEFTAIKKHCIQTLKEATQQEELRRLNPLGLGKKSQIKEYE
>CP033572.1|AZC02558.1|2031246_2032245_-|HEAT-repeat-domain-containing-protein
MSFYYQALDDLDEYNQEFLAQLNDPDEKIRFVALMNIGDEENPDLLPWLHAALQHDSSALVRQEAAKKLESWEDPTSLQVLAQALFDTDVNVKQTASQSLSEVKNAASAPILAPYLKHTDTFALSAILRALKPLRPQQLFDEISALVHHKNAFVRREAVSALSWLQQDQAITILAKIAETDTDDEVRRIATGGLAYSQSISTEVIQALQHSLTSESWQLRVEAALTIGKLRIVQLEAPLIHAVSDLYWQVRIAAVRSLGLLKSHLAVAHLSDNFKHEISNLRKEVALALGEIGTSEAQTLLEQHQNDPDPEVRKAIRIGLNQIGEVKYANQT
>CP033572.1|AZC02557.1|2026271_2027491_+|IS3-family-transposase
MTKLKYTPEIRERAVQLLIESEKDYPSNWAAITAIAPKIGCTPETLRAWHQKHLDEQNPIKVQQISDQEKMKQMEREIKELKRANEILRKAAGFFRPGGARPPTQIMVDFIHNNKALYGVEAICRILPISASTYYRTLDIAENPEHRAKRDLHDLHHAEQIKRIWKESSGRYGVRKVWQQLKREGYVIARCTVARLMKKLGIQGVWRGKNKQTTRSRDDQKRADDLVKRNFTADHPDQLWVSDFTYIQTHSGWVYTAFIIDVFSRAIVGWKVSTRMNTDMVLDALEQALHDRGMPKNVIHHSDRGVQYLSIRYTHRLEAANLRASVGTTGDSYDNALAETVNGLYKTEVIEYLKADWQGLADVQLATLNWVDWFNKKRVHSALGYVSPFEFEAMYYDKINPLGQVA
>CP033572.1|AZC02556.1|2024348_2024669_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MNRLTFINGAIVSATDVRKSWSKIVQCVKDSHKPVFVYTKNAPEAVVLSFEEFQKMQEIIEAVRREQLGQQMVYDLLDINQLTGQPIKHMLLNPKGVFEEVNGQEK
>CP033572.1|AZC02555.1|2021316_2021736_+|hypothetical-protein
MAQHLTDQNIQDIVEILDYWSPNEKLTWERLCKAIEVQLELVPAPTRQTLQKFARIKNAYDLGKKSPTALKILKSKQQKLPASLKIAQARIESLEAKNTRLEKENAMLLEQFVVWQYNAHKYGLSIAKLNEPMNKKSSD
>CP033572.1|AZC02565.1|2043862_2044057_-|hypothetical-protein
MERGKIVLAEFGYGGKLLPSFPKWVIDGQKPSRLAWLLKEQILPPIYWQGMLKGREWMVKPERG
>CP033572.1|AZC02566.1|2044128_2044581_-|NAD(P)/FAD-dependent-oxidoreductase
MYLSADYWLKQGKLKDISIHFYNTGAVLFGVKEYVPALMQYVEKYGSELHFNHQLVKVDGPAKKAWFKVVNDENAALIETNFDMLHVVPPQQAPDFIRASILTDEAGWVSVNPQTLQHTQHANIFALGDVMNAPNAKLLLRREPKPQSLL
>CP033572.1|AZC02567.1|2044553_2045447_-|TIGR01244-family-phosphatase
MADQGIKTLICNRPDGEGADQPNVIEIEEAAQRHSLKVIYQPVTSGKITDQQVTEFKQLYQNAQKPVLAYCRSGMRAISLWALAEVAPQDAALLVETGNKLGFNLKGLVPRILKHDYEPATIPCYSVVIVGAGAAGISVASSLLSREPHLDIVIIDPADTHYYQPGWTMVGGGIFKPQVTARSMASVIPSKVKWMKAAVAGFDPEHNQVILEGCQPIQYKALVVCPGLKLNWHGIEGLVETLGKNGVTSNYRYDLAPYTWELVQQLNGGKAILPSHLCRLSVQVLLKKRCTFQRITG
>CP033572.1|AZC02568.1|2046414_2047686_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MAKLNFESEQNFYILFEQLKALFPNASLFLADTTTQAIHYKFNTDDISVESMAALTQDHHNQYLEINTPKMRQRFIYQEHDIYIAEHRIIGKLHILQPINIENDIANQVELTEQLQDLSKVFNSCSPEMTRMFSIIQRVAITEFPVLVRGESGSGKELVAKAIHDYSQRKNKIFVAINCAALNANILESELFGHVKGAFTGAIRDHKGVFERAAGGTLFLDEIAEIPLELQAKLLRVLETGEFTPVGGEKPIQANVRIITATHKALREEAKAGRFRHDLLYRLRVIPIFIPPLRERKVDIPLIVDQILKESSAQLESMPRHINQKAMQVLLNYDWPGNVRELKNTLLYALTMANGKVEIEVKDLPNELLNAEDYVKLPETNTELSPENVQAALEKYNHNLNMVANIFGISRTTLWRYRQKHKL
>CP033572.1|AZC02569.1|2049800_2050586_-|acetoin-reductase
MVKGLKNKVALVTGAAQGIGRGIALRLAQEGAHIALVDMKQDRLNDVQQEIQALDVNASTFIADVSDREQVYAAINHAEQTLGGFDVMINNAGIAQVQAIADVTPDEFQKIVDINIGGVLWGIQAAATKFKQRQHKGKIINACSIAGHDGFALLGIYSATKFAVRALTQAAAKEYASHGITVNGYCPGIVGTDMWVEIDKRFAEITGAAIGETYKKYVEGIALGRAQTPDDVAALVAFLASEDSDYITGQSILTDGGIVYR
>CP033572.1|AZC02570.1|2052027_2053554_-|diaminohydroxyphosphoribosylaminopyrimidine-deaminase
MSEIKTLEIPKWGLSMEEGTIAQWLIKEGDSFNKGDEICEIETTKIVNVLEAPFAGTLRKILAKDGDTLPVGGLIAVCAESQVSDAEIEKFIASLGGSAAQAPSEQNKAETSAPVAEKAEQPQTVAASASAPAKVAKDDYAVPESLQGYQTSNELFATPHALKLAEKHNVNLAKVTGSGREGRISIQDIQKAVQAAGGQWPDVKQQTQAKVVKSTADDSQVLATPVARRLAKQWGINLNDCRVSGTRGRVCKEDVEAVYYRNNPTSVNEQPVQCVAQPQSTITTVAMNGMRKAIASRLQAAKRNAPHFRLVVDLNVEALQKLRKQINETVPQVKLSINDMLIKAAAAALIKVPEVNVQFDEATQSILQFSQADISVAVAIPNGLITPIVKAANQKSLAQISDDMRDLATRAKTGKLQPDEFQGGSFSISNLGMLGIKQFDAIINPPQGAIMALGASESRAVVENGNVVVREIVTATLSCDHRVIDGAVGAKFLASFKQFVENPALILV
>CP033572.1|AZC02571.1|2055913_2056900_+|lipoyl-synthase
MDLKRQIETGIKLKGIDKVSRIPIKILPTEELPKKPEWIRAKITDFEEIQRIKNLLRQQKLHSVCEEAACPNLPECFGGGTATFMIMGDICTRRCPFCDVAHGRPMPLDENEPKHLAETVANLNLKYVVITSVDRDDLHDGGAAHFVKCIEEIRNHCPDTLIEILVPDFRGRLETALSTLSLSPPDVFNHNIETVPRLYKAMRPGSDYQHSLNLLKRFKKYCPDIKTKCGLMVGLGEIEAEVIALLNDLKDHDVDLVTIGQYLQPSKSHAPIHRFVNLQEFERYTQHGKRLGFKNIWSAPMVRSSYFADRQYFGEPAPKPFSREDVLS
>CP033572.1|AZC02572.1|2059314_2060544_+|GGDEF-domain-containing-protein
MKLQGSNILGQEQIDLLTTRGLNFVWFPKQLETIYRFQYQNGAAYEFRYRAPIILILYLFLSFGIYQVLPTDQVLSWLSYYSWVGIIVLIAWILSFIKKLNQWFDYYVGIGSASAVAITFILINVLENGQDNVLFHAAMMYAIVIIYGAVGMRFYTAIIAGWVGGLVGILVSTYVKGDIDWTFLNRTYTFSSFLGMTLAYATDRQHRENYLQNCMIELNRIELMQQAQQLSLLSQQDALTGLANRRYLDETLDNEWRRALRHETPLTIMMVDIDFFKPYNDTLGHLKGDQCLKDIATAISSIAARSGDLVARYGGEEFLLLFPMTNAQQAQIQVERLMNAIKKIAIVHPCSSVSPYVTISVGVATTIPRLNDSISAFVSRADHALYQAKTNGRNQYQIAVNQEQIVDLT
>CP033572.1|AZC02573.1|2060639_2061731_-|chorismate-synthase
MAGNTIGQLFRVTTCGESHGVGLMAIVDGVPPGLALTEEDLQIDLDRRKPGTSKFATQRKEPDQVEIISGVFEGKTTGTPIGLLIRNTDQKSKDYGNIAQTFRPGHADYTYTQKYGFRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGVLIRGHVTQIGNEVAEKLDWNEVPNNPFFCGDVDAVPRFEALVTSLREQGTSCGAKLEILAEKVPVGWGEPVFDRLDADIAHAMMSINAVKGVEIGDGFAVAGQFGHETRDELTSHGFLANHAGGILGGISSGQTIRVAIALKPTASITTPGKTINLNREDTDVLTKGRHDPCVGVRATPIAEAMLAIVLMDHFLRNRAQNADVVPPFAPIES
>CP033572.1|AZC02574.1|2061743_2062748_-|50S-ribosomal-protein-L3-N(5)-glutamine-methyltransferase
MERPTISPEHLQEAAENLSTIRDFIRFGVSALRQHDAHLGQGTEDYFAESSALVLQTLSLEWSADSEILDAKLLPSEKAEFLSLLERRINERIPTSYLLNLAYFFNKPFYVDERVLIPRSPIAELIEQRFAPYCLDENGQMREALNNLPENTKPKTPQRILDMCTGSGCIAVALAYAYPDAEVDATDISKEALEVASINVEHHNKQYQVALLESDLFAKIPAENQYDLIVSNPPYVDAEDMADLPEEFLHEPELALAAGQDGLDLVRKMLAQAADYLTEDGLIVIEVGNSEWAMRQNFNTVEFNWLTFQKGGSGIFALTAEQCRRYRKLFAEQA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	NZ_CP014283	Bacillus thuringiensis strain Bt185 plasmid pBT1850636, complete sequence	419639-419666	5	0.821
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	NZ_CP032614	Bacillus thuringiensis strain QZL38 plasmid p.1, complete sequence	108823-108850	5	0.821
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	NZ_CP004877	Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMB431, complete sequence	257415-257442	6	0.786
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	NZ_CP040783	Bacillus thuringiensis strain HM-311 plasmid p1, complete sequence	41105-41132	6	0.786
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	NZ_CP022446	Bacillus cereus C1L plasmid pC1L1, complete sequence	332728-332755	6	0.786
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	NZ_CP015592	Bacillus cereus strain AR156 plasmid pAR460, complete sequence	381313-381340	6	0.786
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	NZ_CP007513	Bacillus bombysepticus plasmid pBb, complete genome	24006-24033	6	0.786
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	CP024685	Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-1-490K, complete sequence	356545-356572	6	0.786
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	CP046512	Bacillus cereus strain JHU plasmid p1, complete sequence	385313-385340	6	0.786
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	NZ_CP023246	Bacillus cereus strain HBL-AI plasmid unnamed1, complete sequence	432217-432244	6	0.786
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	NZ_CP053657	Bacillus cereus strain CTMA_1571 plasmid p.1, complete sequence	272622-272649	6	0.786
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	NC_010371	Finegoldia magna ATCC 29328 plasmid pFMC, complete sequence	43415-43442	6	0.786
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	NZ_CP011156	Bacillus cereus strain HN001 plasmid pRML01, complete sequence	245083-245110	6	0.786
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	MG945396	UNVERIFIED: Microviridae sp. isolate 3566-1702, complete genome	1249-1276	7	0.75
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	MG945634	UNVERIFIED: Microviridae sp. isolate 6411-1702, complete genome	1249-1276	7	0.75
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	NZ_CP031267	Staphylococcus warneri strain 16A plasmid unnamed3	3551-3578	8	0.714
CP033572_1	1.2\|102831\|28\|CP033572\|PILER-CR	102831-102858	28	NZ_CP031267	Staphylococcus warneri strain 16A plasmid unnamed3	26803-26830	8	0.714

1. spacer 1.2|102831|28|CP033572|PILER-CR matches to NZ_CP014283 (Bacillus thuringiensis strain Bt185 plasmid pBT1850636, complete sequence) position: , mismatch: 5, identity: 0.821

ttttttcttcaatttctactaccagttg-	CRISPR spacer
ttttttcttcaatttctatta-cattcat	Protospacer
******************.** ** *..

2. spacer 1.2|102831|28|CP033572|PILER-CR matches to NZ_CP032614 (Bacillus thuringiensis strain QZL38 plasmid p.1, complete sequence) position: , mismatch: 5, identity: 0.821

ttttttcttcaatttctactaccagttg-	CRISPR spacer
ttttttcttcaatttctatta-cattcat	Protospacer
******************.** ** *..

3. spacer 1.2|102831|28|CP033572|PILER-CR matches to NZ_CP004877 (Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMB431, complete sequence) position: , mismatch: 6, identity: 0.786

ttttttcttcaatttctactaccagttg	CRISPR spacer
ttttttcttcaatttctacttcttcatc	Protospacer
******************** *.   *

4. spacer 1.2|102831|28|CP033572|PILER-CR matches to NZ_CP040783 (Bacillus thuringiensis strain HM-311 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.786

ttttttcttcaatttctactaccagttg	CRISPR spacer
ttttttcttcaatttctacttcttcatc	Protospacer
******************** *.   *

5. spacer 1.2|102831|28|CP033572|PILER-CR matches to NZ_CP022446 (Bacillus cereus C1L plasmid pC1L1, complete sequence) position: , mismatch: 6, identity: 0.786

ttttttcttcaatttctactaccagttg	CRISPR spacer
ttttttcttcaatttctacttcttcatc	Protospacer
******************** *.   *

6. spacer 1.2|102831|28|CP033572|PILER-CR matches to NZ_CP015592 (Bacillus cereus strain AR156 plasmid pAR460, complete sequence) position: , mismatch: 6, identity: 0.786

ttttttcttcaatttctactaccagttg	CRISPR spacer
ttttttcttcaatttctacttcttcatc	Protospacer
******************** *.   *

7. spacer 1.2|102831|28|CP033572|PILER-CR matches to NZ_CP007513 (Bacillus bombysepticus plasmid pBb, complete genome) position: , mismatch: 6, identity: 0.786

ttttttcttcaatttctactaccagttg	CRISPR spacer
ttttttcttcaatttctacttcttcatc	Protospacer
******************** *.   *

8. spacer 1.2|102831|28|CP033572|PILER-CR matches to CP024685 (Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-1-490K, complete sequence) position: , mismatch: 6, identity: 0.786

ttttttcttcaatttctactaccagttg	CRISPR spacer
ttttttcttcaatttctacttcttcatc	Protospacer
******************** *.   *

9. spacer 1.2|102831|28|CP033572|PILER-CR matches to CP046512 (Bacillus cereus strain JHU plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.786

ttttttcttcaatttctactaccagttg	CRISPR spacer
ttttttcttcaatttctacttcttcatc	Protospacer
******************** *.   *

10. spacer 1.2|102831|28|CP033572|PILER-CR matches to NZ_CP023246 (Bacillus cereus strain HBL-AI plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

ttttttcttcaatttctactaccagttg	CRISPR spacer
ttttttcttcaatttctacttcttcatc	Protospacer
******************** *.   *

11. spacer 1.2|102831|28|CP033572|PILER-CR matches to NZ_CP053657 (Bacillus cereus strain CTMA_1571 plasmid p.1, complete sequence) position: , mismatch: 6, identity: 0.786

ttttttcttcaatttctactaccagttg	CRISPR spacer
ttttttcttcaatttctacttcttcatc	Protospacer
******************** *.   *

12. spacer 1.2|102831|28|CP033572|PILER-CR matches to NC_010371 (Finegoldia magna ATCC 29328 plasmid pFMC, complete sequence) position: , mismatch: 6, identity: 0.786

ttttttcttcaatttctactaccagttg	CRISPR spacer
tttttgcttcaatttctacaacctttct	Protospacer
***** ************* ***  *.

13. spacer 1.2|102831|28|CP033572|PILER-CR matches to NZ_CP011156 (Bacillus cereus strain HN001 plasmid pRML01, complete sequence) position: , mismatch: 6, identity: 0.786

ttttttcttcaatttctactaccagttg-	CRISPR spacer
ctttttcttcaatttctatta-cattcat	Protospacer
.*****************.** ** *..

14. spacer 1.2|102831|28|CP033572|PILER-CR matches to MG945396 (UNVERIFIED: Microviridae sp. isolate 3566-1702, complete genome) position: , mismatch: 7, identity: 0.75

ttttttcttcaatttctactaccagttg	CRISPR spacer
ttttttcttcaatttcttctactttcca	Protospacer
***************** ****.  ...

15. spacer 1.2|102831|28|CP033572|PILER-CR matches to MG945634 (UNVERIFIED: Microviridae sp. isolate 6411-1702, complete genome) position: , mismatch: 7, identity: 0.75

ttttttcttcaatttctactaccagttg	CRISPR spacer
ttttttcttcaatttcttctactttcca	Protospacer
***************** ****.  ...

16. spacer 1.2|102831|28|CP033572|PILER-CR matches to NZ_CP031267 (Staphylococcus warneri strain 16A plasmid unnamed3) position: , mismatch: 8, identity: 0.714

ttttttcttcaatttctactaccagttg	CRISPR spacer
ttttttcttcaatttctactgaacaaca	Protospacer
********************.   . ..

17. spacer 1.2|102831|28|CP033572|PILER-CR matches to NZ_CP031267 (Staphylococcus warneri strain 16A plasmid unnamed3) position: , mismatch: 8, identity: 0.714

ttttttcttcaatttctactaccagttg	CRISPR spacer
ttttttcttcaatttctactgaacaaca	Protospacer
********************.   . ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

950491 : 956259

Burkholderia_phage(33.33%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZC02010.1\|950491_950929_-	regulatory protein GemA	Q6QIE7	Burkholderia_phage	1.2e-21	41.7
AZC02011.1\|950938_951151_-	hypothetical protein	NA	NA	NA	NA
AZC02012.1\|951152_951377_-	hypothetical protein	NA	NA	NA	NA
AZC02013.1\|951438_951756_-	hypothetical protein	NA	NA	NA	NA
AZC02014.1\|951828_952038_-	hypothetical protein	NA	NA	NA	NA
AZC02015.1\|952049_952229_-	hypothetical protein	NA	NA	NA	NA
AZC02016.1\|952212_952524_-	hypothetical protein	A0A1C8HQ73	Pseudomonas_phage	5.2e-14	43.6
AZC02017.1\|952516_952792_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	1.7e-21	61.8
AZC02018.1\|952784_952964_-	hypothetical protein	NA	NA	NA	NA
AZC02019.1\|953580_954264_-	DUF2752 domain-containing protein	A0A2H4JFV8	uncultured_Caudovirales_phage	9.6e-29	48.0
AZC02020.1\|954253_954478_-	hypothetical protein	NA	NA	NA	NA
AZC02021.1\|954470_954665_-	hypothetical protein	NA	NA	NA	NA
AZC02022.1\|954661_954880_-	TraR/DksA family transcriptional regulator	A0A0S2SYW7	Pseudomonas_phage	2.5e-07	41.2
AZC02023.1\|955071_956259_-\|transposase	transposase	Q6QIE1	Burkholderia_phage	1.0e-89	47.3

DBSCAN-SWA_2

1939564 : 2017896

Escherichia_phage(50.0%)

transposase,integrase

attL 2010768:2010827|attR 2017879:2018763

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZC02513.1\|1939564_1940783_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	3.4e-77	52.2
AZC02514.1\|1941454_1943014_+	phospholipase D family protein	NA	NA	NA	NA
AZC02515.1\|1943023_1943611_-	uracil-DNA glycosylase family protein	NA	NA	NA	NA
AZC02516.1\|1943773_1944010_-	hypothetical protein	NA	NA	NA	NA
AZC02517.1\|1944261_1944438_-	hypothetical protein	NA	NA	NA	NA
AZC02518.1\|1947234_1947519_-	pyrroloquinoline quinone biosynthesis peptide chaperone PqqD	NA	NA	NA	NA
AZC02519.1\|1947515_1948274_-	pyrroloquinoline quinone biosynthesis protein C	NA	NA	NA	NA
AZC03630.1\|1949268_1949343_-	pyrroloquinoline quinone precursor peptide PqqA	NA	NA	NA	NA
AZC02520.1\|1949565_1951641_-	polyphosphate kinase 1	NA	NA	NA	NA
AZC02521.1\|1953800_1954202_-	Fur family transcriptional regulator	NA	NA	NA	NA
AZC02522.1\|1954337_1956299_-	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	4.4e-10	29.2
AZC02523.1\|1956515_1959650_+	multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
AZC02524.1\|1959695_1960565_-	isochorismatase	NA	NA	NA	NA
AZC02525.1\|1963526_1964297_-	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase	NA	NA	NA	NA
AZC02526.1\|1965790_1966006_+	MbtH family protein	NA	NA	NA	NA
AZC02527.1\|1973163_1974414_+	enterobactin transporter EntS	NA	NA	NA	NA
AZC02528.1\|1975345_1975603_+	hypothetical protein	NA	NA	NA	NA
AZC02529.1\|1975599_1975890_+	hypothetical protein	NA	NA	NA	NA
AZC02530.1\|1978165_1978858_-	molybdate ABC transporter permease subunit	NA	NA	NA	NA
AZC02531.1\|1978854_1979640_-	molybdate ABC transporter substrate-binding protein	NA	NA	NA	NA
AZC02532.1\|1979822_1980173_-	LysR family transcriptional regulator	NA	NA	NA	NA
AZC02533.1\|1985904_1986435_-	flavin reductase	NA	NA	NA	NA
AZC02534.1\|1986463_1987714_-	FAD-binding oxidoreductase	NA	NA	NA	NA
AZC02535.1\|1987745_1988531_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	3.0e-10	28.2
AZC03631.1\|1988543_1989794_-	dienelactone hydrolase family protein	NA	NA	NA	NA
AZC02536.1\|1990123_1991467_+	MFS transporter	NA	NA	NA	NA
AZC02537.1\|1992846_1993632_-	3-hydroxybutyrate dehydrogenase	NA	NA	NA	NA
AZC02538.1\|1995744_1996568_-\|transposase	IS5-like element ISAba27 family transposase	NA	NA	NA	NA
AZC02539.1\|1996642_1997497_+	putative subclass B3 metallo-beta-lactamase	NA	NA	NA	NA
AZC02540.1\|1997633_1998059_-	BLUF domain-containing protein	NA	NA	NA	NA
AZC02541.1\|1998236_1999455_+\|transposase	IS3-like element ISAba19 family transposase	A0A0N7C1X7	Escherichia_phage	2.4e-78	51.5
AZC02542.1\|1999618_1999882_+	hypothetical protein	NA	NA	NA	NA
AZC02543.1\|2000766_2001594_-	DUF3298 domain-containing protein	NA	NA	NA	NA
AZC02544.1\|2001777_2002167_+	hypothetical protein	NA	NA	NA	NA
AZC02545.1\|2002313_2003195_+	LysR family transcriptional regulator	NA	NA	NA	NA
AZC02546.1\|2003439_2004144_+	CoA transferase subunit A	NA	NA	NA	NA
AZC02547.1\|2006375_2007548_+	acetyl-CoA C-acyltransferase	NA	NA	NA	NA
AZC02548.1\|2007608_2008505_-	LysR family transcriptional regulator	NA	NA	NA	NA
AZC02549.1\|2008742_2009639_-	LysR family transcriptional regulator	NA	NA	NA	NA
AZC02550.1\|2010411_2010633_-	hypothetical protein	NA	NA	NA	NA
2010768:2010827	attL	NA	NA	NA	NA
AZC02551.1\|2010809_2011631_+\|transposase	IS5-like element ISAba27 family transposase	NA	NA	NA	NA
AZC02552.1\|2011588_2011795_-	hypothetical protein	NA	NA	NA	NA
AZC03632.1\|2012207_2013626_+	aspartate ammonia-lyase	NA	NA	NA	NA
AZC02553.1\|2015540_2016767_+\|integrase	site-specific integrase	NA	NA	NA	NA
AZC02554.1\|2017073_2017896_-\|transposase	IS5-like element ISAba27 family transposase	NA	NA	NA	NA
2017879:2018763	attR	NA	NA	NA	NA

DBSCAN-SWA_3

3046308 : 3096888

Salmonella_phage(21.43%)

transposase,tail,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZC03108.1\|3046308_3047131_-\|transposase	IS5-like element ISAba27 family transposase	NA	NA	NA	NA
AZC03109.1\|3048680_3049172_-	flavin reductase	NA	NA	NA	NA
AZC03110.1\|3052069_3052999_+	LysR family transcriptional regulator	NA	NA	NA	NA
AZC03678.1\|3055682_3055829_+	LysR family transcriptional regulator	NA	NA	NA	NA
AZC03111.1\|3055810_3056533_+	LysR family transcriptional regulator	NA	NA	NA	NA
AZC03112.1\|3059266_3060496_-	CoA transferase	NA	NA	NA	NA
AZC03113.1\|3060547_3061870_-	MFS transporter	NA	NA	NA	NA
AZC03679.1\|3064611_3065787_-	zinc-binding dehydrogenase	NA	NA	NA	NA
AZC03114.1\|3068962_3069703_-	3'-5' exonuclease	A0A0S0NDC6	Pseudomonas_phage	8.3e-26	35.4
AZC03115.1\|3069777_3070110_-	hypothetical protein	NA	NA	NA	NA
AZC03116.1\|3070113_3070605_-	hypothetical protein	NA	NA	NA	NA
AZC03117.1\|3070608_3071040_-	DUF2528 family protein	NA	NA	NA	NA
AZC03118.1\|3074454_3074637_-	hypothetical protein	NA	NA	NA	NA
AZC03119.1\|3074641_3074875_-	hypothetical protein	NA	NA	NA	NA
AZC03120.1\|3074871_3075081_-	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
AZC03121.1\|3075163_3075508_+	hypothetical protein	NA	NA	NA	NA
AZC03122.1\|3076623_3078096_+	hypothetical protein	NA	NA	NA	NA
AZC03123.1\|3079216_3079441_-	hypothetical protein	NA	NA	NA	NA
AZC03680.1\|3079443_3079881_-	hypothetical protein	NA	NA	NA	NA
AZC03124.1\|3079959_3080256_-	hypothetical protein	NA	NA	NA	NA
AZC03125.1\|3080369_3080528_+	Com family DNA-binding transcriptional regulator	NA	NA	NA	NA
AZC03126.1\|3080533_3081337_+	DNA adenine methylase	A0A2H4J8Q1	uncultured_Caudovirales_phage	1.1e-87	60.8
AZC03127.1\|3082822_3083245_-\|tail	phage tail protein	Q9ZXJ9	Pseudomonas_virus	4.7e-34	52.1
AZC03128.1\|3086180_3086300_-\|tail	GpE family phage tail protein	A0A0M4R2P3	Salmonella_phage	3.7e-05	52.8
AZC03129.1\|3086703_3087222_-\|tail	phage major tail tube protein	F1BUU2	Erwinia_phage	8.3e-49	56.1
AZC03130.1\|3087232_3088405_-\|tail	phage tail sheath protein	A0A077K9Y4	Ralstonia_phage	2.0e-159	69.5
AZC03131.1\|3089216_3090056_-	hypothetical protein	E5EZ16	Acinetobacter_phage	1.3e-06	33.8
AZC03132.1\|3090067_3090415_-	hypothetical protein	A0A172Q098	Acinetobacter_phage	1.1e-09	36.5
AZC03133.1\|3090594_3091860_-	hypothetical protein	Q9ZXK6	Pseudomonas_virus	7.7e-32	32.5
AZC03134.1\|3092393_3093299_-\|plate	baseplate assembly protein	S4TNY7	Salmonella_phage	7.4e-85	55.0
AZC03135.1\|3093295_3093640_-\|plate	baseplate assembly protein	Q7Y4D7	Escherichia_virus	5.9e-19	43.9
AZC03136.1\|3094693_3095194_-\|tail	phage tail protein	A0A2H4J906	uncultured_Caudovirales_phage	8.3e-38	61.4
AZC03137.1\|3095190_3096051_-	DUF3380 domain-containing protein	A4JWU0	Burkholderia_virus	2.9e-46	42.4
AZC03138.1\|3096675_3096888_-\|tail	phage tail protein	E5G6M9	Salmonella_phage	2.7e-14	57.6

DBSCAN-SWA_4

3594511 : 3608910

uncultured_Caudovirales_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZC03389.1\|3594511_3595602_-\|transposase	IS4 family transposase ISAba1	NA	NA	NA	NA
AZC03390.1\|3595706_3596528_+	carbapenem-hydrolyzing class D beta-lactamase OXA-23	NA	NA	NA	NA
AZC03391.1\|3597753_3598086_-	hypothetical protein	NA	NA	NA	NA
AZC03392.1\|3598187_3599277_+\|transposase	IS4 family transposase ISAba1	NA	NA	NA	NA
AZC03393.1\|3599281_3600748_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	2.3e-213	79.6
AZC03394.1\|3600760_3601612_+	universal stress protein	A0A2H4J154	uncultured_Caudovirales_phage	8.2e-70	45.9
AZC03395.1\|3602050_3602422_+	hypothetical protein	NA	NA	NA	NA
AZC03396.1\|3604218_3605334_-\|transposase	transposase	NA	NA	NA	NA
AZC03397.1\|3605363_3606284_-\|transposase	transposase	NA	NA	NA	NA
AZC03398.1\|3606288_3608199_-\|transposase	transposase	NA	NA	NA	NA
AZC03399.1\|3608199_3608910_-\|transposase	heteromeric transposase endonuclease subunit TnsA	I6WI48	Vibriophage	4.1e-06	29.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP033572

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection