CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
CP028962	Burkholderia sp. IDO3 chromosome 1, complete sequence	0 crisprs	RT,csa3,cas3,DinG,c2c9_V-U4,PD-DExK,DEDDh	0	2
CP028965	Burkholderia sp. IDO3 plasmid p1, complete sequence	3 crisprs	csa3,PD-DExK	3	4
CP028964	Burkholderia sp. IDO3 chromosome 3, complete sequence	0 crisprs	c2c9_V-U4,RT,csa3,WYL,Cas14u_CAS-V	0	0
CP028963	Burkholderia sp. IDO3 chromosome 2, complete sequence	0 crisprs	WYL,cas3,DEDDh,csa3,DinG,RT	0	3

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

354204 : 406985

Burkholderia_phage(28.95%)

tail,portal,head,capsid,holin,plate,integrase,terminase

attL 350111:350125|attR 359170:359184

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
350111:350125	attL	NA	NA	NA	NA
AXK61490.1\|354204_355257_-\|integrase	site-specific integrase	A0A077KGX2	Edwardsiella_phage	4.6e-78	42.7
AXK61491.1\|355133_355460_-	DNA-binding protein	NA	NA	NA	NA
AXK61492.1\|355456_355693_-	hypothetical protein	A9YWV8	Burkholderia_phage	8.2e-28	73.1
AXK61493.1\|355689_356043_-	hypothetical protein	NA	NA	NA	NA
AXK61494.1\|356286_356496_+	hypothetical protein	A9YWV5	Burkholderia_phage	3.0e-26	82.4
AXK63746.1\|356498_356834_-	DUF551 domain-containing protein	NA	NA	NA	NA
AXK61495.1\|357208_358444_-	phosphoadenosine phosphosulfate reductase	R9TRT5	Rhizobium_phage	2.3e-169	69.5
AXK61496.1\|358457_358721_-	hypothetical protein	NA	NA	NA	NA
AXK61497.1\|358735_360532_-	DNA cytosine methyltransferase	Q9ZXI4	Pseudomonas_virus	1.6e-179	59.3
359170:359184	attR	NA	NA	NA	NA
AXK61498.1\|360630_361113_-	hypothetical protein	A0A0K2FHI1	Achromobacter_phage	2.8e-30	47.4
AXK61499.1\|361114_361309_-	hypothetical protein	A9YX20	Burkholderia_phage	1.3e-18	83.9
AXK61500.1\|361308_361614_-	hypothetical protein	NA	NA	NA	NA
AXK61501.1\|361640_362651_-	reverse transcriptase	A0A0N7AE80	Bacillus_phage	2.2e-45	34.1
AXK61502.1\|362982_363360_-	four helix bundle protein	NA	NA	NA	NA
AXK61503.1\|363375_363867_-	DUF1566 domain-containing protein	NA	NA	NA	NA
AXK61504.1\|363922_364282_-	DUF1566 domain-containing protein	NA	NA	NA	NA
AXK61505.1\|364472_364682_-	hypothetical protein	Q3HQW6	Burkholderia_phage	3.8e-21	72.5
AXK61506.1\|364981_365275_-	hypothetical protein	NA	NA	NA	NA
AXK61507.1\|365324_365675_-	HTH domain-containing protein	NA	NA	NA	NA
AXK61508.1\|365628_365826_-	hypothetical protein	NA	NA	NA	NA
AXK61509.1\|366684_366972_+	hypothetical protein	C7BGF6	Burkholderia_phage	1.4e-29	69.5
AXK63747.1\|366939_367341_-	hypothetical protein	C7BGF7	Burkholderia_phage	4.2e-48	73.7
AXK61510.1\|367426_367723_+	Cro/Cl family transcriptional regulator	C7BGF8	Burkholderia_phage	2.4e-29	84.9
AXK61511.1\|367723_367981_+	hypothetical protein	NA	NA	NA	NA
AXK61512.1\|367944_368151_-	hypothetical protein	NA	NA	NA	NA
AXK61513.1\|368315_368615_+	DNA-binding protein	E5E3P2	Burkholderia_phage	7.4e-18	56.0
AXK61514.1\|369012_369309_+	hypothetical protein	A1YZR1	Burkholderia_virus	2.1e-20	51.1
AXK61515.1\|369329_370175_+	hypothetical protein	A4JX52	Burkholderia_virus	3.8e-83	62.0
AXK61516.1\|370171_371257_+	helix-turn-helix domain-containing protein	Q8W6P0	Burkholderia_virus	2.5e-47	53.3
AXK61517.1\|371253_371817_+	hypothetical protein	Q3HQZ9	Burkholderia_phage	3.1e-89	85.0
AXK61518.1\|371816_372209_+	MarR family transcriptional regulator	NA	NA	NA	NA
AXK61519.1\|372205_372649_+	DUF1364 family protein	Q3HR02	Burkholderia_phage	5.8e-75	87.8
AXK61520.1\|372651_372984_+	hypothetical protein	Q8W6N6	Burkholderia_virus	4.5e-40	73.8
AXK61521.1\|372980_373469_+	hypothetical protein	K7ZPX8	Xanthomonas_citri_phage	2.0e-12	33.3
AXK61522.1\|373465_373705_+	hypothetical protein	Q6JIF5	Burkholderia_virus	9.8e-13	44.9
AXK61523.1\|373704_373965_+	hypothetical protein	Q6V7S5	Burkholderia_virus	8.7e-15	48.8
AXK61524.1\|373989_374388_+	hypothetical protein	NA	NA	NA	NA
AXK61525.1\|374511_374838_+	hypothetical protein	NA	NA	NA	NA
AXK61526.1\|374963_375272_+	hypothetical protein	NA	NA	NA	NA
AXK61527.1\|375268_375961_+	hypothetical protein	A0A1W6JTE1	Pseudomonas_phage	3.0e-14	31.5
AXK61528.1\|376125_376716_+	hypothetical protein	NA	NA	NA	NA
AXK63748.1\|376699_378733_+\|terminase	phage terminase large subunit family protein	G8EXZ6	Synechococcus_phage	1.0e-142	47.4
AXK61529.1\|378774_379011_+\|head,tail	phage head-tail adapter protein	NA	NA	NA	NA
AXK61530.1\|379007_380663_+\|portal	phage portal protein	A0A291AUL8	Sinorhizobium_phage	1.2e-93	35.8
AXK61531.1\|380691_381588_+	S49 family peptidase	A0A286MNI8	Klebsiella_phage	1.9e-45	39.5
AXK61532.1\|381609_382197_+	hypothetical protein	NA	NA	NA	NA
AXK61533.1\|382224_382638_+\|head	head decoration protein	A0A291AUM0	Sinorhizobium_phage	1.9e-11	42.6
AXK61534.1\|382711_383758_+\|capsid	major capsid protein	A0A0C5ABI0	Bacteriophage	1.1e-31	29.8
AXK61535.1\|383790_384003_+	hypothetical protein	NA	NA	NA	NA
AXK61536.1\|384006_384351_+	hypothetical protein	NA	NA	NA	NA
AXK61537.1\|384379_384946_+	hypothetical protein	NA	NA	NA	NA
AXK61538.1\|384958_385138_+	DUF2635 domain-containing protein	NA	NA	NA	NA
AXK61539.1\|385134_386625_+\|tail	phage tail protein	M1FN90	Enterobacteria_phage	5.8e-103	43.5
AXK61540.1\|386694_387069_+\|tail	phage tail protein	NA	NA	NA	NA
AXK61541.1\|387072_387633_+\|tail	phage tail assembly protein	NA	NA	NA	NA
AXK61542.1\|387796_389221_+	multidrug DMT transporter	Q8HAC1	Salmonella_phage	1.9e-23	37.7
AXK61543.1\|389237_390791_+\|tail	phage tail protein	NA	NA	NA	NA
AXK61544.1\|390790_391933_+	hypothetical protein	U5P0H6	Shigella_phage	4.0e-27	29.5
AXK63749.1\|391974_392496_+\|plate	baseplate assembly protein	Q8W617	Enterobacteria_phage	5.3e-27	40.2
AXK61545.1\|392499_392946_+	hypothetical protein	U5P0R9	Shigella_phage	1.9e-17	44.9
AXK61546.1\|392947_394111_+\|plate	baseplate J/gp47 family protein	C9DGQ6	Escherichia_phage	1.3e-22	29.2
AXK61547.1\|394117_394804_+	DUF2313 domain-containing protein	A0A2P9JZK7	Alteromonadaceae_phage	7.9e-31	37.7
AXK61548.1\|396001_397783_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
AXK61549.1\|398451_398859_-	hypothetical protein	NA	NA	NA	NA
AXK61550.1\|398924_399632_+	lysozyme	A0A059VA40	Pseudomonas_phage	4.3e-32	45.0
AXK61551.1\|399671_399977_+	hypothetical protein	NA	NA	NA	NA
AXK61552.1\|400087_400306_+	hypothetical protein	NA	NA	NA	NA
AXK61553.1\|400317_400761_+	hypothetical protein	NA	NA	NA	NA
AXK61554.1\|400757_401573_+	exotoxin	A0A141ZNL4	Faustovirus	7.5e-12	32.6
AXK61555.1\|401608_401824_+	hypothetical protein	Q3HQV3	Burkholderia_phage	1.0e-24	70.8
AXK61556.1\|402477_404928_-\|holin	phospholipase C, phosphocholine-specific	NA	NA	NA	NA
AXK61557.1\|405031_405307_-	hypothetical protein	NA	NA	NA	NA
AXK61558.1\|405336_406017_-	HAD-IB family hydrolase	NA	NA	NA	NA
AXK61559.1\|406040_406985_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA

DBSCAN-SWA_2

1641353 : 1714649

Acanthocystis_turfacea_Chlorella_virus(14.29%)

plate,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXK62520.1\|1641353_1642736_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
AXK62521.1\|1642751_1644071_+	DotU family type VI secretion system protein	NA	NA	NA	NA
AXK62522.1\|1644072_1647702_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
AXK62523.1\|1647698_1648379_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
AXK62524.1\|1648438_1650871_+	serine/threonine protein kinase	M1I231	Acanthocystis_turfacea_Chlorella_virus	1.2e-09	27.0
AXK62525.1\|1650857_1651967_+	type VI secretion system protein TssA	NA	NA	NA	NA
AXK63865.1\|1652026_1652581_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
AXK62526.1\|1652573_1654100_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
AXK62527.1\|1654171_1654663_+	Hcp1 family type VI secretion system effector	NA	NA	NA	NA
AXK62528.1\|1654673_1655228_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
AXK62529.1\|1655232_1657104_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
AXK62530.1\|1657100_1658228_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
AXK62531.1\|1658240_1660913_+	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	8.0e-79	30.3
AXK62532.1\|1660909_1663114_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.3e-45	29.1
AXK62533.1\|1663129_1664395_+	hypothetical protein	NA	NA	NA	NA
AXK62534.1\|1669153_1670644_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
AXK62535.1\|1670836_1672003_-	porin	NA	NA	NA	NA
AXK62536.1\|1672082_1673330_-	CoA transferase	NA	NA	NA	NA
AXK62537.1\|1673339_1674140_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
AXK62538.1\|1674191_1675520_-	MFS transporter	NA	NA	NA	NA
AXK62539.1\|1675679_1676438_+	IclR family transcriptional regulator	NA	NA	NA	NA
AXK62540.1\|1676642_1677593_-	LysR family transcriptional regulator	NA	NA	NA	NA
AXK62541.1\|1677709_1679230_+	methylmalonate-semialdehyde dehydrogenase (CoA acylating)	NA	NA	NA	NA
AXK62542.1\|1679447_1680152_-	SDR family oxidoreductase	NA	NA	NA	NA
AXK62543.1\|1680284_1681187_+	transcriptional regulator GcvA	NA	NA	NA	NA
AXK62544.1\|1681610_1682864_+	porin	NA	NA	NA	NA
AXK63866.1\|1683110_1683737_+	ubiquinol-cytochrome c reductase iron-sulfur subunit	NA	NA	NA	NA
AXK62545.1\|1684054_1684546_+	peptidoglycan-associated lipoprotein Pal	NA	NA	NA	NA
AXK62546.1\|1684669_1686271_-	APC family permease	NA	NA	NA	NA
AXK62547.1\|1686579_1687092_-	hypothetical protein	NA	NA	NA	NA
AXK62548.1\|1687550_1688810_-	cytochrome c	NA	NA	NA	NA
AXK62549.1\|1688806_1689502_-	(2Fe-2S)-binding protein	NA	NA	NA	NA
AXK62550.1\|1689498_1692375_-	xanthine dehydrogenase family protein molybdopterin-binding subunit	NA	NA	NA	NA
AXK62551.1\|1692889_1694443_+	diguanylate cyclase	G3MA91	Bacillus_virus	2.8e-23	39.8
AXK62552.1\|1694694_1694982_+	hypothetical protein	NA	NA	NA	NA
AXK62553.1\|1695212_1696247_+	deacylase	NA	NA	NA	NA
AXK62554.1\|1696401_1697322_+	recombination-associated protein RdgC	A0A218M310	Acidovorax_phage	1.8e-54	39.3
AXK62555.1\|1697676_1698237_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AXK62556.1\|1698288_1699230_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AXK62557.1\|1699447_1700806_+	FMN-dependent monooxygenase	NA	NA	NA	NA
AXK62558.1\|1700863_1702645_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	3.5e-30	37.8
AXK62559.1\|1702679_1703612_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AXK62560.1\|1703714_1704809_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
AXK62561.1\|1704909_1705875_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
AXK62562.1\|1706174_1707092_+	alpha/beta hydrolase	NA	NA	NA	NA
AXK62563.1\|1707088_1707520_+	MarR family transcriptional regulator	NA	NA	NA	NA
AXK62564.1\|1708020_1710048_+	TonB-dependent receptor	NA	NA	NA	NA
AXK62565.1\|1710416_1710794_+	hypothetical protein	NA	NA	NA	NA
AXK62566.1\|1710963_1712370_+	alpha,alpha-trehalose-phosphate synthase (UDP-forming)	NA	NA	NA	NA
AXK62567.1\|1712660_1714649_-\|protease	ATP-dependent zinc metalloprotease FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	9.1e-104	42.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP028965

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CRISPR-Cas detection and classification

Crispr_ID: CP028965_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028965_1

71456-71562

Orphan

Consensus_repeat	Method
TGCCGCGCGACAATCAGGATGAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP028965_1

>merge|CP028965|1|71456-71562|CRISPRCasFinder
TGCCGCGCGACAATCAGGATGAGAATGCTGCGGCGAGGTTGATGATGTCGATGTTGATTGACGCTGGCGAGCGTTGCCTGCCTGCCGCGCGTCAATCAGGATGAGAA

>CP028965|1|1|71456-71562|CRISPRCasFinder
TGCCGCGCGACAATCAGGATGAGAA	TGCTGCGGCGAGGTTGATGATGTCGATGTTGATTGACGCTGGCGAGCGTTGCCTGCC
TGCCGCGCGTCAATCAGGATGAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP028965.1\|AXK68026.1\|69080_70259_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271175
CP028965.1\|AXK68315.1\|68853_69084_+\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68030.1\|76249_77329_+\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68029.1\|74564_76076_-\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|366234
CP028965.1\|AXK68025.1\|67753_68470_-\|translesion-DNA-synthesis-associated-protein-ImuA	unknown	unknown	gnl\|CDD\|380271
CP028965.1\|AXK68028.1\|72404_73766_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
CP028965.1\|AXK68031.1\|77325_79278_+\|integrase	unknown	unknown	gnl\|CDD\|271187
CP028965.1\|AXK68023.1\|62771_63071_-\|H-NS-histone-family-protein	unknown	unknown	gnl\|CDD\|376390
CP028965.1\|AXK68027.1\|71569_71881_-\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68035.1\|81017_81440_-\|arsenate-reductase-(glutaredoxin)	unknown	unknown	gnl\|CDD\|182200
CP028965.1\|AXK68033.1\|79851_80280_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224167
CP028965.1\|AXK68313.1\|62280_62673_-\|DUF2471-family-protein	unknown	unknown	gnl\|CDD\|371166
CP028965.1\|AXK68312.1\|58717_60520_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235877
CP028965.1\|AXK68024.1\|63198_66348_-\|error-prone-DNA-polymerase	unknown	unknown	gnl\|CDD\|235553
CP028965.1\|AXK68314.1\|66354_67815_-\|DNA-polymerase-Y-family-protein	unknown	unknown	gnl\|CDD\|176458
CP028965.1\|AXK68022.1\|61201_62131_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|334163
CP028965.1\|AXK68021.1\|60651_61131_-\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68034.1\|80302_81025_-\|arsenical-resistance-protein-ArsH	unknown	unknown	gnl\|CDD\|274260
CP028965.1\|AXK68032.1\|79274_79712_+\|TetR-family-transcriptional-regulator	unknown	unknown	unknown
CP028965.1\|AXK68036.1\|81461_82535_-\|arsenical-resistance-protein	unknown	unknown	gnl\|CDD\|213563

Protein	Function_ID	Function_description	E-value
CP028965.1\|AXK68026.1\|69080_70259_+\|site-specific-integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	2.59435e-10
CP028965.1\|AXK68024.1\|63198_66348_-\|error-prone-DNA-polymerase	gnl\|CDD\|235553	PRK05672, dnaE2, error-prone DNA polymerase; Validated.	0
CP028965.1\|AXK68036.1\|81461_82535_-\|arsenical-resistance-protein	gnl\|CDD\|213563	TIGR00832, Uncharacterized_transporter_slr0944, arsenical-resistance protein. The Arsenical Resistance-3 (ACR3) Family (TC 2.A.59) The first protein of the ACR3 family functionally characterized was the ACR3 protein of Saccharomyces cerevisiae. It is present in the yeast plasma membrane and pumps arsenite out of the cell in response to the pmf. Similar proteins are found in bacteria, often as part of a four gene operon with an regulatory protein ArsR, a protein of unknown function ArsH, and an arsenate reductase that converts arsenate to arsenite to facilitate transport. [Cellular processes, Detoxification, Transport and binding proteins, Anions].	3.51846e-125
CP028965.1\|AXK68029.1\|74564_76076_-\|IS21-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	2.22765e-14
CP028965.1\|AXK68313.1\|62280_62673_-\|DUF2471-family-protein	gnl\|CDD\|371166	pfam10616, DUF2471, Protein of unknown function (DUF2471). The function of this family is unknown. Members all come from Burkholderia spp. BDAG_04162 is annotated as Serine/threonine-protein kinase, but this could not be confirmed.	1.09707e-16
CP028965.1\|AXK68025.1\|67753_68470_-\|translesion-DNA-synthesis-associated-protein-ImuA	gnl\|CDD\|380271	NF033429, ImuA_translesion, translesion DNA synthesis-associated protein ImuA. A three-gene cassette encoding ImuA, ImuB, and ImuC (""inducible mutagenesis"") is induced by DNA damage, is capable of DNA synthesis across DNA damage lesions, and consequently is associated with mutagenesis. This family, ImuA (previously misnamed SulA in Pseudomonas putida) shows some homology to SulA itself and to RecA. ImuB resembles Y-family polymerases but may be catalytically inactive. ImuC is a C-family polymerase, and catalytically active.	1.57447e-79
CP028965.1\|AXK68031.1\|77325_79278_+\|integrase	gnl\|CDD\|271187	cd01187, INT_tnpB_C_Tn554, Putative Transposase B from transposon Tn554, C-terminal catalytic domain. This family includes putative Transposase B from transposon Tn554. It belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain containing six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	0.00674146
CP028965.1\|AXK68023.1\|62771_63071_-\|H-NS-histone-family-protein	gnl\|CDD\|376390	pfam00816, Histone_HNS, H-NS histone family.	1.25231e-16
CP028965.1\|AXK68035.1\|81017_81440_-\|arsenate-reductase-(glutaredoxin)	gnl\|CDD\|182200	PRK10026, PRK10026, arsenate reductase (glutaredoxin).	1.10057e-73
CP028965.1\|AXK68033.1\|79851_80280_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224167	COG1246, ArgA, N-acetylglutamate synthase and related acetyltransferases [Amino acid transport and metabolism].	1.50063e-22
CP028965.1\|AXK68028.1\|72404_73766_-\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	7.70494e-16
CP028965.1\|AXK68312.1\|58717_60520_+\|hypothetical-protein	gnl\|CDD\|235877	PRK06850, PRK06850, hypothetical protein; Provisional.	1.33305e-26
CP028965.1\|AXK68314.1\|66354_67815_-\|DNA-polymerase-Y-family-protein	gnl\|CDD\|176458	cd03468, PolY_like, DNA Polymerase Y-family. Y-family DNA polymerases are a specialized subset of polymerases that facilitate translesion synthesis (TLS), a process that allows the bypass of a variety of DNA lesions. Unlike replicative polymerases, TLS polymerases lack proofreading activity and have low fidelity and low processivity. They use damaged DNA as templates and insert nucleotides opposite the lesions. The active sites of TLS polymerases are large and flexible to allow the accomodation of distorted bases. Expression of Y-family polymerases is often induced by DNA damage and is believed to be highly regulated. TLS is likely induced by the monoubiquitination of the replication clamp PCNA, which provides a scaffold for TLS polymerases to bind in order to access the lesion. Because of their high error rates, TLS polymerases are potential targets for cancer treatment and prevention.	7.38476e-58
CP028965.1\|AXK68022.1\|61201_62131_-\|site-specific-integrase	gnl\|CDD\|334163	pfam00589, Phage_integrase, Phage integrase family. Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase are Arg-173, His-289, Arg-292 and Tyr-324.	4.72375e-14
CP028965.1\|AXK68034.1\|80302_81025_-\|arsenical-resistance-protein-ArsH	gnl\|CDD\|274260	TIGR02690, arsenical_resistance_protein_ArsH_putative, arsenical resistance protein ArsH. Members of this protein family occur in arsenate resistance operons that include at least two different types of arsenate reductase. ArsH is not required for arsenate resistance in some systems. This family belongs to the larger family of NADPH-dependent FMN reductases (pfam03358). The function of ArsH is not known. [Cellular processes, Detoxification].	3.26238e-124

>CP028965.1|AXK68026.1|69080_70259_+|site-specific-integrase
MRYVRATEEFVFAGRPRPGFPLILDDSMTPAQPFHDYLLYRLLERGKTLDPKTWEAYGRRLWDFARFLQANDWSWNDPFMSVGQSVVRVYRDWQAQDLKLDPATVNDRLRLVAAMYQWAHERGRIDRLPFGCSDIAVYGIEHDLAHVTGGRKTLSRPAVLLNEWDKEPAFLTVDQLKIARQSIRSASQRLLFDLMARVGLRSVEARTFPLSYVFDPSAQKALKPGTFIEVRLDPRDMEIKLNKARVVHVPYSLMEDMYAYTTYERNGLVGAAERKELVLTIHGQRYSKEAAVKVCTDLSNRVGFRVRPLMLRHSYAIHTLLLLRSRPEIKLEPLMYVRDRLGHASVQTTMVYLQQIERLLGAEALAMMDEFDRLYGVSKALASAPQVSTVDP
>CP028965.1|AXK68315.1|68853_69084_+|hypothetical-protein
MAEHTKLDRDFAPVRAFNTRRVHVTAAGADWELLVDGARFFDTRERKGGGGAVDLVMHLWRVPFKQAVKMLREAGA
>CP028965.1|AXK68025.1|67753_68470_-|translesion-DNA-synthesis-associated-protein-ImuA
MHPALAHPEAIHPSLWRASQLARSSVRGVDTGHPELTAELPGGGWPAGALIELLAPQPGIGELRLLAPVLARAAGKSIMLIQPPHALQPLALAYWGIDPSGFVTLPAPRTADALWAAEQALRAGTCAAVLLWQQHVRADALRRLNLAAQSGQALFYFFRPAAAARDASPAPLRLALAPKRDGIDVTFVKRRGPARDTPLFVPLSPSPILLNRHASLDRRASAAPQPRNVPAAIAGAVA
>CP028965.1|AXK68314.1|66354_67815_-|DNA-polymerase-Y-family-protein
MHLPHLNLETFRPRSPAPSPDDARGLVVLEGGRVVALDRAARALGVVAGMRRGGVLSLAPDAQIRERDAARERELVLGVAYALLQFTPSVVDAEEAVVVLDVTASLRLFHGIRALRQRVRDVVASFGVTAAISVASSGPAAWMVARGLRGGLALSARSLHRALARVSLVVAPDARRYANWFEDLGCETLADLQRLPRAGLQKRCGTQLLDWLDQVAGTAPAAYDWLEMPPSFDTRVELMDRVEHAEALLFVARRLILQLTGWLAAKQLDVAAFALLLEHERGRDAIAPTEIEIALGAPTRFEEHLTRLVKERLGQVELAGPVIAVRLIARSVQEAAAPSDSLFPEPGGTPQDHARLLELLTARLGAENVLVPAPIADYRPEPAARWVPMRDAPKPAPLPADLPRPAWLLAKPVPLLTRQHRPFYGTPLRMVSPGERIEGGWQDAQTVTRDYFVAEDDNGICYWIYKERPTASDESEARFFLHGLFG
>CP028965.1|AXK68024.1|63198_66348_-|error-prone-DNA-polymerase
MDAGSFGALPAYAELQVASDFSFLHGASRAEEYVARAAQLGYSAIAITDECSLAGVVRAHVEAKAANMPLIVGSHFRLTAADGSPALAFTALAMNRDGYGNLCEFISLGRMRSKKGTYRLAPLDLEHPEAPYTHLRGLPDCIAILSHDFPANEQRLDAQVEWLVRVFGDHAWVALTLHARAMDDIHRGVVERVAARHGVPVVATSWPLMHVRSRKPLQDVLTGIRVGRPVSECGYELAPNAERHLRSRLRLANLYPAGALEETVRVARRCTFSLDDLKYEYPDELVPAGTDPATYLREQTYIGARRRFPAGIPVDVQAQIEHELQLIADLKYEAYFLTVYDIVQFAREQGILCQGRGSAANSSVCYCLGVTEVDPSRQSMLFERFISKERNEPPDIDVDFEHQRREEVMQYIYRKYGRDRAALTAAVTTYRPRSALREAGKALGVDPAIVDRVAKQHHWFDSRADLLQRFSEAGLDPEAPLNQQWAAFAAQLLGYPRHLSQHSGGFVISRGKLTRLVPVENAAMEDRSIIQWDKDDIEALGILKIDVLALGMLSMVRRALDMISEKRGETFELQDIPAEDKPTYDMLCDGDSMGVFQVESRAQMSMLPRLRPQCFYDLVIEVAIVRPGPVQGGMVHPFLRRRQGLEPVTYPSPDVEKALKRTLGVPIFQEQVMQVAMLAAGFSAGEADQLRRAMAAWKRKGGLEPYHERLVSGMLARGYDHEFAEAIFAQIKGFGDYGFPESHAASFALLVYSSAWLRRHEPAVFLAALLNSQPMGFYTPSQLLQDARRRGVEVLAVDVNVSTWDSAIEGPTTSSPVRLGFSLLRGMREDVAGRIELARAVRPFVDVADLARRAQLDRHDLQVLARANALRSLAGGNRRAALWLAAAAVPDRDLLRGTERDDAVPALPQASEGKEIVTDYNAMGFTLGRHPLALLRDRLALDRLQSAEQLATLRSGQLARACGLVTVRQRPGTANGVLFMTLEDETGQVNVILWPGLLEKFRKEALGAALLAVYGVWQAEGKVRHLIASKLVDRTELLGALPTTAREFC
>CP028965.1|AXK68023.1|62771_63071_-|H-NS-histone-family-protein
MSTYQELLAKRTALEAEIDAAKGAERAAALSNVLRLVNEFDISSREIYGVARKGTRRRPDPKYRDPESGATWSGRGRPPAWIDGKDRVPFEIKRHGALS
>CP028965.1|AXK68313.1|62280_62673_-|DUF2471-family-protein
MNLASTAAHPDSEVDPVWYAHALTLATEDLRRVVISLTERYVGAGLPHAISWPLLLEIEEQAFSDLAFQSRNEPAIVAALPRIGPTTMPGVNFSGLIDWSHTDPSLPMVYRCVRDLLVGVSTTAVGRDAA
>CP028965.1|AXK68022.1|61201_62131_-|site-specific-integrase
MDEPTLWLSAPTEAYQQWQRTEAAGADRRAFSPRSIVQHEAMFERFMRHLAAAQRSLATFGPDHLESFFADLDRRCKPGTTTRLRYEKLLDRLGRHLVNVGVRKTNPAAAYALTQTWPEDEPVPVYLLEADDHRLQASIRAIDGLDDRALRNRAIVGLLLSTGITAQEIRQATAVDLDLSPARPHLQIPKRGPREARRVNIAEFAVPALTQWRTLSAAADSPLLFPSPRAGGPMTDEMLGRIVRDELLAIDVRLPDMSPRTLRNTFARRLLLAGRSNDDVMHLLGLTSQRTVIRIRATIPTEPQAALQT
>CP028965.1|AXK68021.1|60651_61131_-|hypothetical-protein
MDYVSRYMDLVYSTNGGIAVCRYRLLALAPEPTQLVIQVENHGGNKDILITDHIVRDGILNRIADRELTGVPFDMLCVALTEAGQHHIVFVEADLEDYIHRGYPYERSAQPAARGRHIERISINSRDLVVGRARLQTAHATPTLADDSLAAILDRPTSA
>CP028965.1|AXK68312.1|58717_60520_+|hypothetical-protein
MFSEILVKMESAIDALVALIRQGYTLSNALSGGKDSTCTAILMLEAVRRAGTDVSREHFMTSADTTIENPSMHWHLHAMLDEIRDGYAHADAPVSVHVAKPSLASQFVVATIGRGTLPRTPENGVKNGKRIRACAADWKVDPQNRLRVTLERSAAAGGSGEVVTILGNRFGESGSRATAMAARNENALRPVRNADGFLTFSPVAEWSTGCVWTMLSLFAEDAGRPFPSPVSSESIRRLSDLYRAGNEGTCGVILGEGGARAACGSRFGCAFCCVTGERDRSMESMVKEAGHRHLEGLNRFRNYLMAVQWDLGRRELVSRKLSEAGYLAVKPDVLSYLERVRLLQYLLTLDALEVERAERHEAALATGEIPETPENRVLCDVQFEMITPAQLVAIDFYLSMHHYAPHAFPALSVWFDVHRLGRRYHVPVVDPLPKIDIPHHGWFFVGAYDAEVPTDGLRDYAAEQWNRYRQPERPSRYARTRSGEQIVYFEEGDQFDVDVEAACAFVTCSFDAGWAVKAQQHSGMESARFWLNEGILRLPAGMAGRYQEMAKRGQYFAHLAERHNLTPAELDRFLVDRAISNTEHLTMQNLAPVDLFSQAA
>CP028965.1|AXK68027.1|71569_71881_-|hypothetical-protein
MKHNAHLQLVTRDDTSDSSTTKPIARTAAQRQRAYRLRRKRAVIDAIGEEACASRVTMLALLGEGLAALDNSDTSTRLIESKRHCVRRVLQAIVTRYAIDLTD
>CP028965.1|AXK68028.1|72404_73766_-|IS110-family-transposase
MASISNAPVRHRTVGIDLAISAVQVAQIFDDGRAIGKPIRFRLTSTDLRRFVSAIKSGVGADTPITAVMEPTGMAWFPVANWLQRAGIKVIRVKGQRVKALRKYLSEHAKTDAADAHVLGAIPGFGGRGLDPVHVPGPEQHSLQRLTKQRHRYQELVCSARRRVLDLIRWACPALEPVLPDTVTQLTLAILGELLDPRKVVAMRRDVLARFLSQHASGNHPKSGPFIDSLVEKLKAAAEETIELHGDSVDFTALQFEVAQEVEHLRLWDRHVRAIEREVEQIYQRVHPSDALRSIPGIGATLAPLLIGVLGYAKRFRNEDHIRGFCGMFPTRSSSGGIEKPGQRLTKSGSDRVKRALYIAADVARKIDPDLAAVYWRLMVNKGHHHKQAICAVATRLINRIYRVLKTGEPYVLRDQEGNSISVQEGKRIVAAQFKVPLEVRQSRRNQPMPEPA
>CP028965.1|AXK68029.1|74564_76076_-|IS21-family-transposase
MPGRHVNDHQMRLYMKYRSKEQPTKAGARAGFSAATAYRIEQDPRPPSKKKAPRTRRRADPLAAIFDAEIVPLLQSAPGIRPVAVLDEMLRRHPDLPGNVRRTLERRIRDWRALHGEERDVMFRQVHEPGRLGLSDFTEMDSLGVTVAGVALDHRLYHFRLACSGFEHAHVILGGESYVALAEGLQNALWVLGGAPREHRSDSLSAAFRNLEREARDDLTTRYEALCAHYGMQPTRNNRGVAHENGSIESPHGHLKNAVRDALLLRGSKDFDDLDTYRRFIDEHVCRINARNGKRIDAERPQLQPLPPQRTTDYEQTRVYVSSTGGFVLRKVFYTVPSRLIGHRLRVRLYDDRLELFLGSTALMTLQRGRPGPSGKHGHVVNYRHIIHALRRKPMALLNLVYRDQVFPREAYRLTFERLCEQLPERAACKTMVELLSLAHERNCEAQLAQALEQCLADGQLPDLHALSSRFEAKPASLPQVNVQLPSLRDYEALLGLQMEVAA
>CP028965.1|AXK68030.1|76249_77329_+|hypothetical-protein
MLIDARYERQASTQPSEPPAEQDLCFDLSEGAVLQQAIASTRELVCEAPPALKQRIWLYRAEASAGSIKRGNITCLDSRSLRRAIQGVIQRHNLLGDDGLPLRLNLSRLRKSRFDRALRTADGDIATTANLMGNTPRVAGANYPSMNAARKAEAASFMNGDYTALMRTEGQAPRGPEIQPVQVRPFRLGKDGASALPTPTPVSACSDSISGEHAPNDGHSHCDRYVMCLFCSSFAIVGTVDELWRLFSFQMFAQAELDYLDEALGPERTADGLLEDLRDRYRVAIPYIDDFTQRQFARSGVAQARARTASGLHPYWQHQMTMSSRARSRVLAPEPHDDASQSVAVGLQARRTRRAGPRA
>CP028965.1|AXK68031.1|77325_79278_+|integrase
MSHTSALVLGTPQEHAEDLVVPVGSMPAPRALRAFELLAAQPISLVGIPPAERDAIVVTAVADAAGHEHPVSRFGDRVWDLASEVEAKNRKGSASKIVWPDDVPNALVDDAKAALYCAQRRGPRGRQWSGSSIAEIGHRAVQVLRHLAQLGLGDFSQVRALHLSDHITDLRRTLKPMSVHKRLQIIDLVWSFHMEVLHPLPEHPWMGLALWDVCGGNEGDRGPSGRTGMTPVIPRSVQRILFAHCEASLAQAEDLFWARDAGEVGAPNRAALTAIRNAVLYLLQISSGMRNSESTGVTSGCWRTEQRNGVTYHWVRTREIKTTGGAEVDFLVPPEAISALEILQRYAEPLQARLADEARWLEDVLAQGPDLTGHLSNGMKMAEAAHRLNHVRGIGRHLVLGLNVKASDHLGTGSRVEVLSSTSCAYQLKQLAVAAGTEWDLANHQCRRTFAYNVANSRLGRMGLVFLKWQLKHASMSWTQLYAASPYQDHALYREFEEEMFEARLGLLEGWAHPDALLSGGAGKKIMQTRARAARDLKQLLRQTAESVELRSTGHAWCISGTHGCHGQGVYDPSMCGGCSQAIIDQGQASAWQMIHLDNLRLAAITDCGPVVADKARRAVERSKQVLHNLGCALPTDDQAQAYTAAREGA
>CP028965.1|AXK68032.1|79274_79712_+|TetR-family-transcriptional-regulator
MSTRAGTTPAEPQTESAPRRRSRGKTREELQLAMLRVKNKGLKLSISAVATEAGVSAGLIHNTYPDIAEEIRAQVGRGTRQQRDAKVAEVKEVRGRLKALRMERDAALADVARLASINETLRQEVAMLRAAASGKMVVLPPQMDV
>CP028965.1|AXK68033.1|79851_80280_-|GNAT-family-N-acetyltransferase
MEIRPATVDDLASIETLLHQCGLPVVGVSDHLQDFVVAMEGSTMCGCGGIEHYRDAALLRSIAVAEHARGSGVGQRIVSQLVAACHSLQVRSLVLLTTTAENYFTRQGFVRVARDDVPPLVLASSQFQGVCPGSAASMLRVL
>CP028965.1|AXK68034.1|80302_81025_-|arsenical-resistance-protein-ArsH
MSEQLKDLSQLDATHFRVPDAAELRPAAPSTHPPRLLLLYGSLRERSFSRLLVEEAERLLTAMGAEVRVFNPSGLPLPDDAPESHPKVVELRELVMWSEGMVWCSPERHGAMTGIMKSQIDWIPLSVGAVRPTQGKTLAVMQVSGGSQSFNAVNQMRVLGRWMRMLTIPNQSSVAKAFAEFDEAGRMKPSSYYDRVVDVMEELVKFTLLTRDIGPYLVDRYSERKESAEELSKRVNQRSI
>CP028965.1|AXK68035.1|81017_81440_-|arsenate-reductase-(glutaredoxin)
MTDITIYHNPNCGTSRNTLALIRNSGEEPIIIEYLKTPPSRETLVKLLADAGLTVREVLREKGTPYAELGLDDPKWTDEQLLDLIGQHPILMNRPIVVTPIGTKLCRPSEAVLDILPNPQKGSFTKEDGEVVINAEGKRV
>CP028965.1|AXK68036.1|81461_82535_-|arsenical-resistance-protein
MNTSNVAPPGKAVAKPAINFFERYLTVWVALCIVAGIALGQVLPGLFQQIGRMEYAQVNLPVGLLIWVMIIPMLVKVDFGALHEVRQHVKGIGVTLIVNWLVKPFSMAFLGWLFIRHLFAPMLPADQLDSYIAGLILLAAAPCTAMVFVWSRLTGGDPLFTLSQVALNDSIMVIAFAPLVGLLLGMSAITVPWATLLTSVVLYIVIPVILAQIWRKVLLAKGQAAFDAAMAKIGPWSIAALLATLVLLFAFQGEAILKQPLVIALLAVPILIQVFFNSALAYWLNRAVGEKHNIACPSALIGASNFFELAVAAAISLFGFHSGAALATVVGVLIEVPVMLLVVRIVNQSKGWYECRA

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Crispr_ID: CP028965_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028965_2

229048-229154

Orphan

Consensus_repeat	Method
TTCTCATCCTGATTGACGCGCGGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP028965_2

>merge|CP028965|2|229048-229154|CRISPRCasFinder
TTCTCATCCTGATTGACGCGCGGCAGGCAGGCAACGCTCGCCAGCGTCAATCAACATCGACATCATCAACCTCGCCGCAGCATTCTCATCCTGATTGTCGCGCGGCA

>CP028965|2|2|229048-229154|CRISPRCasFinder
TTCTCATCCTGATTGACGCGCGGCA	GGCAGGCAACGCTCGCCAGCGTCAATCAACATCGACATCATCAACCTCGCCGCAGCA
TTCTCATCCTGATTGTCGCGCGGCA

Protein	Signature genes	Signature genes Name	Protein_function
CP028965.1\|AXK68156.1\|219115_219478_+\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68157.1\|219937_220165_+\|DUF2933-domain-containing-protein	unknown	unknown	gnl\|CDD\|378689
CP028965.1\|AXK68163.1\|228728_229040_+\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68172.1\|242569_242965_-\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68335.1\|220487_223403_-\|Tn3-like-element-IS1071-family-transposase	unknown	unknown	gnl\|CDD\|376561
CP028965.1\|AXK68334.1\|219585_219885_+\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68164.1\|230283_232185_-\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68169.1\|240162_240348_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366690
CP028965.1\|AXK68173.1\|243153_243822_-\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68162.1\|227898_228732_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|136670
CP028965.1\|AXK68159.1\|224229_224538_+\|P-II-family-nitrogen-regulator	unknown	unknown	gnl\|CDD\|198006
CP028965.1\|AXK68171.1\|242355_242607_-\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68158.1\|223635_224193_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372729
CP028965.1\|AXK68167.1\|235859_238568_-\|type-VI-secretion-system-tip-protein-VgrG	unknown	unknown	gnl\|CDD\|226032
CP028965.1\|AXK68170.1\|241107_241925_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
CP028965.1\|AXK68165.1\|232193_233378_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271175
CP028965.1\|AXK68166.1\|234883_235885_-\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68161.1\|226390_227902_+\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|366234
CP028965.1\|AXK68168.1\|238848_239268_+\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68160.1\|224604_225042_-\|TetR-family-transcriptional-regulator	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP028965.1\|AXK68158.1\|223635_224193_+\|hypothetical-protein	gnl\|CDD\|372729	pfam13798, PCYCGC, Protein of unknown function with PCYCGC motif. This domain contains a PCYCGC motif and four other conserved cysteines. Its function is unknown.	1.03278e-05
CP028965.1\|AXK68157.1\|219937_220165_+\|DUF2933-domain-containing-protein	gnl\|CDD\|378689	pfam11666, DUF2933, Protein of unknown function (DUF2933). This bacterial family of proteins has no known function.	2.32479e-06
CP028965.1\|AXK68335.1\|220487_223403_-\|Tn3-like-element-IS1071-family-transposase	gnl\|CDD\|376561	pfam01526, DDE_Tnp_Tn3, Tn3 transposase DDE domain. This family includes transposases of Tn3, Tn21, Tn1721, Tn2501, Tn3926 transposons from E-coli. The specific binding of the Tn3 transposase to DNA has been demonstrated. Sequence analysis has suggested that the invariant triad of Asp689, Asp765, Glu895 (numbering as in Tn3) may correspond to the D-D-35-E motif previously implicated in the catalysis of numerous transposases.	5.9923e-135
CP028965.1\|AXK68170.1\|241107_241925_+\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	7.79122e-26
CP028965.1\|AXK68165.1\|232193_233378_-\|site-specific-integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	8.04665e-12
CP028965.1\|AXK68162.1\|227898_228732_+\|hypothetical-protein	gnl\|CDD\|136670	PRK08181, PRK08181, transposase; Validated.	7.71721e-155
CP028965.1\|AXK68167.1\|235859_238568_-\|type-VI-secretion-system-tip-protein-VgrG	gnl\|CDD\|226032	COG3501, VgrG, Uncharacterized protein conserved in bacteria [Function unknown].	4.20317e-130
CP028965.1\|AXK68161.1\|226390_227902_+\|IS21-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	2.22765e-14
CP028965.1\|AXK68159.1\|224229_224538_+\|P-II-family-nitrogen-regulator	gnl\|CDD\|198006	smart00938, P-II, Nitrogen regulatory protein P-II. P-II modulates the activity of glutamine synthetase.	2.4201e-16
CP028965.1\|AXK68169.1\|240162_240348_-\|hypothetical-protein	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.00769e-05

>CP028965.1|AXK68163.1|228728_229040_+|hypothetical-protein
MKHNAHLQLVTRDDTSDSSTTKPIARTAAQRQRAYRLRRKRAVIDAIGEEACASRVTMLALLGEGLAALDNSDTSTRLIESKRHCVRRVLQAIVTRYAIDLTD
>CP028965.1|AXK68162.1|227898_228732_+|hypothetical-protein
MNHEFDATRLSLLLNDLRLPAIKQIWSSFAERSDTEGWPAARLLMALAEHEIAERDRRRIERHLRDARLLPGKTLENFDFDAVPMVSRAHVSALCAGDGWLRNGANLILLGPSGGGKSHLSSAIGLSLLENGWKVLFARTTNLVQRLQVARRELSLESAINRLDRFDLLILDDFAYVSKDQAETSVLFELISARYEHRSLLLTANQPFGEWDRIFPDRAMTVAAVDRLVHHSTIFELNVESYRRRTALERKQQGPGRPASIATPNNVGVPPRPEDQQ
>CP028965.1|AXK68161.1|226390_227902_+|IS21-family-transposase
MPGRHVNDHQMRLYMKYRSKEQPTKAGARAGFSAATAYRIEQDPRPPSKKKAPRTRRRADPLAAIFDAEIVPLLQSAPGIRPVAVLDEMLRRHPDLPGNVRRTLERRIRDWRALHGEERDVMFRQVHEPGRLGLSDFTEMDSLGVTVAGVALDHRLYHFRLACSGFEHAHVILGGESYVALAEGLQNALWVLGGAPREHRSDSLSAAFRNLEREARDDLTTRYEALCAHYGMQPTRNNRGVAHENGSIESPHGHLKNAVRDALLLRGSKDFDDLDTYRRFIDEHVCRINARNGKRIDAERPQLQPLPPQRTTDYEQTRVYVSSTGGFVLRKVFYTVPSRLIGHRLRVRLYDDRLELFLGSTALMTLQRGRPGPSGKHGHVVNYRHIIHALRRKPMALLNLVYRDQVFPREAYRLTFERLCEQLPERAACKTMVELLSLAHERNCEAQLAQALEQCLADGQLPDLHALSSRFEAKPASLPQVNVQLPSLRDYEALLGLQMEVAA
>CP028965.1|AXK68160.1|224604_225042_-|TetR-family-transcriptional-regulator
MSSRAGTSPDDTRPGSAPRRRSRGKTREALQLAILRVKTRGLKLSISSVAAEAGVSAGLIHNTYPDIAEEIRTQVGRGIRQQRDATVAEVKKVREQLKTVRAERDAALADVATLASINETLRQEIATLQAVASGKIHVLPPVRDV
>CP028965.1|AXK68159.1|224229_224538_+|P-II-family-nitrogen-regulator
MELKCVVAVLRPEVLTALEQRLGALHIHGMTVTKAKGFGAHPNFFGNDWTTEHIRIEVFTVAESVDALVEEITTVANEQSGGDGVVAVVPVERFLRVRSATP
>CP028965.1|AXK68158.1|223635_224193_+|hypothetical-protein
MKRYKRHQSGSAANERSGRVVKVKLNLLSLLALILAVSTALVWGPSLVHWAFGPKSAAVTLENTVQQVPGWRVGMLRPDGLRIISSGVSDASHVLNPVQFPDIAVRHAYWVATQIPATLNKLYCWCGCENRGEHRSNLQCFEDKMAVSCPVCQGTAEIAYQMTQAGVRDAAKIQAAVDAKWAPKG
>CP028965.1|AXK68335.1|220487_223403_-|Tn3-like-element-IS1071-family-transposase
MQGWHTTFLGMRGLPRDISDFEMKAFFTFDGAERDAINARRGDSHKLGLALHIGFLRMSGRLLGAFRVIPVALWRHLGNELGIAAPEVASLRAMYERGRTLFDHQQVACTVLGFQWMSEHQRRSLVRELRDEVARCADRDQLLVRARQWLYKNKLVIVHERAIRTLIAAALAQLEVETGTAIAASVDPATLDRWRASVSELRPDGQTQQSWLWAAPAKHSTRQISEVLERIDLLYTLDVHKHLADIPDLILRRYARRLVSRPPSAGAKIKEPARTVEVACFLRYCLFTTTDQLILMVQRRIADLWRQAAADVPATVNWAAMYKTLLGELVALSAQGAVPDAELRARLEALITETQKRKPPSRASLVREGLIDGIRPVRSLLVAIAKLPWQATGEHPAIEYLAKLQALYLKGSRKLPVEVVAPSLGMIWQVSISSPDRERAFQALEVATLFALRRAVRNGSVWIEHSLSFRGRARLFFTDERWQAESKKHYARLSLPSKAATFLKPLLARVTAGVDAVAAAARSGVLRVDDELHLSPLPAEDEDPEVTKLRAALDHRIGEVQLPEVILAVDAQVRFSWIMLGREPRSTDELLMVYAGIMAHGTSLTAVECARMIPQLSATSIRQAMRWARDERRLSQACQAVLEFMQRHPIAATWGRSDLASSDMMTMETTKRVWQARLDPRRNTPSIGIYSHVKDRWGIFHAQPFVLNERQAGVAIEGVIRQEKLETSQLAVDTHGYTDFAMSHARLLGFDLCPRLKELKQRHLFVPRGTKVPAEIAAVCEANVDVALIEKHWDSLVHLAASVMSGHASAVAALARFGSAAQGDPIYEAGVQLGRLLRTAFLADYFVKDAFRNELRRVLNRGEAVNALKRAIYTGRISPAQAKRVDEMQAVADALSLMANIVMAWNTSQMQAVLDRWSNRRQVIPPELIGKIAPTRLESINLRGVFRFPVDRYADQILPSRPNASITGTNG
>CP028965.1|AXK68157.1|219937_220165_+|DUF2933-domain-containing-protein
MKCNWKTMVAVGSALVAVIALGYWAFPPLRGPLATLAVIASGFICPLSMIFMMRGMQSHADGSGVDTRLTDKAEH
>CP028965.1|AXK68334.1|219585_219885_+|hypothetical-protein
MEIYMNASHARMAVLSTLLVAASAVSFAATGSASGTSAQDREHGHGSMMMGGMMGGCPMMGGSAGLDSKTAMRMHAEMMRAMSDIMMKYSDQAGAAPSK
>CP028965.1|AXK68156.1|219115_219478_+|hypothetical-protein
MKFWVKLVACFLIAWLPMLGYPAQAALCPEMSSMPAVQHHMKAASAIEATGCTSGTKPLGTSDRPSACHAGMGSAVCGMLAIPMSHRVGIVVSTADYRAITPFLAEQFIPELPAPPPRSL
>CP028965.1|AXK68164.1|230283_232185_-|hypothetical-protein
MVRKKNYNVSENRAAPVGVISASLERPKPGADDACIDMVALLGLEARFPQRIKTLDLRDWLGRGIDDWVCSSGFCLKAMLLSGARATASVTTYFGQLPYLFEYLAGSSQTPLPQRPKLPSDLSPMHVQHFIGWLQKRAQAEGWRPSSTRNTYRGVKAVLAEMFAQGFIEGEPSRFFRRGALPWSSEDSLQTSLSDAEQERLAKAIKSDLVDVHHGRLQLKQSAVQGLRLLLVAHRQGLNPTPLLEMCRDALAPGFLPGTILIRTAKHRSKKIRSNVGRSALGRHASNQPNEQADEQNLCFDLSEGAVLQQAIASTRELVGEAPSAFKTRIWLYRAEASAGSTKRGNITCLDSKSLNRAIEGVIERRSLLGDGGLPLRVNLSRLRKSRFDRALRTADGDIAITANLMGNTPRVAGVNYPSMNEARKADAASFMNGDYTVLMRAEAQAPRGNEIRPVQVEPFKVGKGSISAPPSPTPVSACSDSISGEHAPNDGRSHCDRYVMCLFCSSFAIVGTVDELWRLFSFQMFAQAELDYLDEALGPERTTDGLLEDLRDRYRVVIPYIDDFTQRQFARSRVAQARAKTVSGLHPYWQHQMTMSRRARHRASAPDLRVDGSHGDTAIPRIRGTQQAGPRA
>CP028965.1|AXK68165.1|232193_233378_-|site-specific-integrase
MRYVRATDEFVFAGRPRPGFPLILDDSMEPAQPFHDYLLYRLLESGKALDQKTWEAYGRRLWDFARFLQANEWCWDDPFMSVGQSVVSVYRDWQAQDLKLDPATINARLELVTAMYRWAHERGRIDRLPFTCSDVAVYGIEHDLTHITGGRKRSSRPAVLLNEWNKEPAFLTADQLKIVRQSIRSAAQRLLFDLMARVGLRSVEARTFPLSYVVDPRTQKAWKPGTFIDVRLDPRDMEIKFNKSRVVHVPYSLMEDMYAYTTFERNGLADAADRKELILTIHGQRYSKESAVKVYTDLSNTVGFRVRPLMLRHSYAIHTLLLLRSRPEIPMEPLMYVRDRLGHASVQTTMVYLQQIERLLGAEALAMMDEFDRLYGVGKALATAPHASTVDPRH
>CP028965.1|AXK68166.1|234883_235885_-|hypothetical-protein
MMTATKKRKTEKRHVKHASTTGTDQDSLVKAVIQNDSGEWVRPATGDKFVIDETPKFPVITFEIKSEQPPPYQWKWTITWDAQVSGLREKPRGKKLKTFSDTGSFSSNDKTWVADLDGKILGGKLVVEVTAGTEQFRRTVFIVGTNPSKDAVLEFLKAQKDAVGFDRVINQESHYKNFINADNEPVVAFDNGYGMTQMTNPAPTYEQVWNWKENIKVGIKLYQEKQGYAKKDLAGHPYTEDQLIRATFSRWNGSVYYRWDEASNAWVPNGTIMCDPDTSNIGWDMSKDANKDKTVEELHKRDKDTYKSGKSGRSDEHAWIYSGICYADHMANN
>CP028965.1|AXK68167.1|235859_238568_-|type-VI-secretion-system-tip-protein-VgrG
MDALELMRVIRGGLIQQDRLLRLDTAVGNDVLLPHQMIGESRLGRDFEFVVDVVTTTPNVELKNLIAQPATLWIQQPGAVYAPHNGYVHTARRLGADGGLTFHQISIASWMHFLRFRRDQRIWQDKPVDTIVADVFNAHPQARGFFEFHLSRVLPSLSFCRQDETDWNFVHRLLESEGLYGYWKHDADGRAHRLVITDRLAALEEALPVTFSRSGTTVASDALRQWSATRTLQSTSLTTRTFDYKSPASAVNAKGTSMPTMPNQGDLPDQAEIYEYTGAYTFLTQERGDALSKTRLEEWESRSKRFFGIGGWRAADAGKRFTLNGHPDHDCDSPEQREFVAIGVRWIVRNNLPIAASAARMPHSLDKPIAESGIDDLDVAGYVSSYADGSIGAYQVEVEAQRTTIPFRSPFEHVKPQTHLETAIVVGPQNEEVYTDELNRIKVRFVWDRINPGNEGASCWVRVVQSDTGNGYGAVHPPRVGEEVLIDYVGGDCDRPIAIARVYNGATKPQWHTHGLLSGYRSKEFAGAGYNQMVMDDSTGQNRLQLFSSQGNSALHLGYLIQQTGNVRGTYLGSGFDLRTDNYGAVRANRGLYVTTYPNAADSQPLDARDTQQQLVRAESLLESLSDVGTAHNAESLQAGYDALKQLTDATQESIAGSASGGRTAGGGTGAANAFKDPVMLFGSPAGIGFSTNETVHMSAAQHVNIVSGQSTHFAIGKSLIASVANKLSIFVQSAGMKLFAARGKIEVQAHSDNIELTAQKTVKVLSATANVEVAADQEVFLTSGGAYIRIANGDIQIHAPGKIDIKGATHSLNGPTAQGYVLPGLPHAGDVPRYHEQFHLVDEDGKTVLPHTRYEIESESGKRWSGYSDANGFTQHVYTDQPEALSLTVYKEVDDDSDEEA
>CP028965.1|AXK68168.1|238848_239268_+|hypothetical-protein
MADANGDRSNKVKDFNVFLEKASLGLAGVCLLIIVGVLTVQLPLNPMLTWAIRFTSVALPLFFAIYMAKDEASRLLQIEHPMAIQRLTILSYVGVAGLFLLGGAIVCIVAHYSAGLALVVLFMLLGSGELSRWLAKTKI
>CP028965.1|AXK68169.1|240162_240348_-|hypothetical-protein
MKKSRFTEEQIAYALKQAELGTPVAEVCCKMGIPSAANHQSASKVLFLCHHGLSACVHSDT
>CP028965.1|AXK68170.1|241107_241925_+|IS5-family-transposase
MAKPIIDDELWTLIEPLLPPPKPRREKNPGRLPVSNRAALTGILFVLKTGLRWRDLPAEMGCGSGVTCWRRLRDWQAAGVWDRLHELLLAKLRAADQIDFSRAAVDSSSIRAVGAGPKTGPNPTDRARPGSKHHIVTDANGTPLAAILTGANVNDVMQLLPLIDAIPPIRGLRGHPLQRPRVVYADRGYDSERHRRALRDRGIEPVIAKRRTEHGSGLGKYRWVVERTHAWLHHFRRLRIRFERRADIHGAFLKLGCCLICWNTLRRADQSL
>CP028965.1|AXK68171.1|242355_242607_-|hypothetical-protein
MKTTARYTKGRGEASVHARAIVRAHADHDLVEIDIAGQLNSEHHFRPISSADEAEMLARQLLDAAAKVRAVVPAARVSTPKVA
>CP028965.1|AXK68172.1|242569_242965_-|hypothetical-protein
MPHGKDEVAHLEQLLAHAWCVDTRGWTEDGAIYNIYSAAELYEDKSDPAVDLRLLDIGGGSDGVGPAKAYYARTPVVDLFVTPRVAMRLRELLAVVDQMYEHSPTGRARDRAISNIRRPHENDSEIYERSR
>CP028965.1|AXK68173.1|243153_243822_-|hypothetical-protein
MPEVGRLHEGLAVAGERYRVVIQPRSYPFALDESDVTLFIAVDARSQSWGNEWARISGDAVIPARRQDVRLAVTAGGSDELQVLPARHADLPEFRTGITLTLEPGMRDPILTALSRVERVAQRTAADCQAIEPMLGRTLAPYSPTVLKPHEVNAIAAIVAGIVLQGKGVPDAISWSVLLSPEYSTWAFGENGDHPHYAELGTALRQPAVQAMLAEAGRDVRA

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Crispr_ID: CP028965_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028965_3

315456-315562

Orphan

Consensus_repeat	Method
TGCCGCGCGACAATCAGGATGAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP028965_3

>merge|CP028965|3|315456-315562|CRISPRCasFinder
TGCCGCGCGACAATCAGGATGAGAATGCTGCGGCGAGGTTGATGATGTCGATGTTGATTGACGCTGGCGAGCGTTGCCTGCCTGCCGCGCGTCAATCAGGATGAGAA

>CP028965|3|3|315456-315562|CRISPRCasFinder
TGCCGCGCGACAATCAGGATGAGAA	TGCTGCGGCGAGGTTGATGATGTCGATGTTGATTGACGCTGGCGAGCGTTGCCTGCC
TGCCGCGCGTCAATCAGGATGAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP028965.1\|AXK68345.1\|312038_313757_+\|transposase	unknown	unknown	gnl\|CDD\|366234
CP028965.1\|AXK68233.1\|316707_318219_-\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|366234
CP028965.1\|AXK68231.1\|315569_315881_-\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68238.1\|324206_325559_-\|two-component-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|182388
CP028965.1\|AXK68235.1\|320374_321736_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
CP028965.1\|AXK68224.1\|308565_309123_-\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
CP028965.1\|AXK68226.1\|309484_309985_-\|transposase	unknown	unknown	unknown
CP028965.1\|AXK68234.1\|318562_319585_+\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
CP028965.1\|AXK68227.1\|309981_310308_-\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68240.1\|326222_326981_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227049
CP028965.1\|AXK68229.1\|311155_311542_-\|DUF86-domain-containing-protein	unknown	unknown	gnl\|CDD\|225236
CP028965.1\|AXK68344.1\|311538_311829_-\|nucleotidyltransferase	unknown	unknown	gnl\|CDD\|224583
CP028965.1\|AXK68232.1\|315877_316711_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|136670
CP028965.1\|AXK68239.1\|325534_326200_-\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|223816
CP028965.1\|AXK68225.1\|309116_309488_-\|hypothetical-protein	unknown	unknown	unknown
CP028965.1\|AXK68236.1\|323065_323680_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
CP028965.1\|AXK68230.1\|313759_314668_+\|transposase	unknown	unknown	gnl\|CDD\|377533
CP028965.1\|AXK68237.1\|323746_324178_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|225308
CP028965.1\|AXK68228.1\|310562_310919_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380411
CP028965.1\|AXK68223.1\|306089_308384_+\|heavy-metal-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783

Protein	Function_ID	Function_description	E-value
CP028965.1\|AXK68345.1\|312038_313757_+\|transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	3.2798e-16
CP028965.1\|AXK68238.1\|324206_325559_-\|two-component-sensor-histidine-kinase	gnl\|CDD\|182388	PRK10337, PRK10337, sensor protein QseC; Provisional.	3.55962e-58
CP028965.1\|AXK68228.1\|310562_310919_-\|cupin-domain-containing-protein	gnl\|CDD\|380411	cd07008, cupin_yp_001338853-like, Klebsiella pneumoniae yp_001338853.1 and related proteins, cupin domain. This family includes bacterial proteins homologous to Klebsiella pneumoniae yp_001338853.1, an uncharacterized conserved protein with double-stranded beta-helix domain. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	4.34403e-55
CP028965.1\|AXK68224.1\|308565_309123_-\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	1.43944e-65
CP028965.1\|AXK68240.1\|326222_326981_-\|hypothetical-protein	gnl\|CDD\|227049	COG4705, COG4705, Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown].	4.3364e-73
CP028965.1\|AXK68234.1\|318562_319585_+\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.24589e-48
CP028965.1\|AXK68233.1\|316707_318219_-\|IS21-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	2.22765e-14
CP028965.1\|AXK68229.1\|311155_311542_-\|DUF86-domain-containing-protein	gnl\|CDD\|225236	COG2361, COG2361, Uncharacterized conserved protein [Function unknown].	2.51459e-34
CP028965.1\|AXK68344.1\|311538_311829_-\|nucleotidyltransferase	gnl\|CDD\|224583	COG1669, COG1669, Predicted nucleotidyltransferases [General function prediction only].	3.88855e-24
CP028965.1\|AXK68232.1\|315877_316711_-\|hypothetical-protein	gnl\|CDD\|136670	PRK08181, PRK08181, transposase; Validated.	1.67882e-155
CP028965.1\|AXK68239.1\|325534_326200_-\|DNA-binding-response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.87378e-71
CP028965.1\|AXK68236.1\|323065_323680_+\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	1.58809e-50
CP028965.1\|AXK68230.1\|313759_314668_+\|transposase	gnl\|CDD\|377533	pfam05621, TniB, Bacterial TniB protein. This family consists of several bacterial TniB NTP-binding proteins. TniB is a probable ATP-binding protein which is involved in Tn5053 mercury resistance transposition.	2.52611e-99
CP028965.1\|AXK68237.1\|323746_324178_-\|EamA-family-transporter	gnl\|CDD\|225308	COG2510, COG2510, Predicted membrane protein [Function unknown].	4.54056e-45
CP028965.1\|AXK68235.1\|320374_321736_+\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	7.70494e-16
CP028965.1\|AXK68223.1\|306089_308384_+\|heavy-metal-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0

>CP028965.1|AXK68230.1|313759_314668_+|transposase
MEEYPIIDLSHLLPAAQGLARLPADERIHRLRADRWIGYPRAVEALNRLEILYTWPNKQRMPNLLLVGPTNNGKSMIVEKFRRTHPARADADQEHIPVLVVQMPSEPSVIRFYVALLAAMGAPLRPRPRLPEMEQLALALLRKVGVRMLVIDELHNVLAGNSVNRREFLNLLRFLGNELRIPLVGVGTRDAYLAIRSDDQLENRFEPMMLPVWEANHDCCSLLASFAASLPLRRPSSIATLDMARYLLTRSEGTIGELAHLLMAAAIVAVESGEEAINHRTLSMADYTGPSERRRQFERELM
>CP028965.1|AXK68345.1|312038_313757_+|transposase
MLNTRVHQSEMSMATDTAPITEHGVATLPEQAWERARRRAEIIGPLAQSETVGHEAADAAAQALGLSRRQVYVLIRRARLGSGLVTDLALGQSSGGKGKGRLPESVERIIRELLQKRFLTKQKRSLAAFHREVVRACKLQKLRVPARNTVALRIAGLDPREVTHRREGQDAARDLQGVGGVPPPVSAPLEQVQIDHTVIDLIVVDERDRQPIGRPYLTLAIDVFTRCVVGMVVTLEAPSAVSVGLCLVHAACDKRPWLEGLNVEMDWPMSGKPRLLYLDNAAEFKSEALRRGCEQHGIRLDYRPLGQPHYGGIVERIIGTAMQMIHDELPGTTFSNPDQRGEYASEKMAALTLRELERWLTLAVGTYHGSVHNGLLQPPAARWAEAITRTGVPTVITRATAFLVDFLPIIRRTLTRTGFVIDHIHYYADALKPWIARRDRLPAFLIRRDPRDISRIWVLEPEGQHYLEIPYRTLSHPAVTLWEQRQALAKLRQQGREQVDESALFRMIGQMREIVTTAQKATRKARRDADRRQHLKATATPVKTTPPPGADMDGQQADNQPPAKPFDQIEEW
>CP028965.1|AXK68344.1|311538_311829_-|nucleotidyltransferase
MRPSVVLDMKRSAVREAVGRFRAANPRVFGSVLHGTDRDGSDLDLLVDALPGATLLDLGDLEEELKSLLGVDVDLLTPGDLPPKFRAKVLAEAQPI
>CP028965.1|AXK68229.1|311155_311542_-|DUF86-domain-containing-protein
MSENRLPDYLDHIQQAATDARSFVEGMAKDDFLADKRTQQAVIMSLIVIGEAATKVMDGYVEFTQAHADVPWRSMRNMRNRMAHGYFDINLDVVWETVQEWLPALLQQLPAVRQDADDEDRNDKGMEP
>CP028965.1|AXK68228.1|310562_310919_-|cupin-domain-containing-protein
MTVESRIFSVAEYVQPSEGEPIRSVVLETRDSIIVVWHVHPGQEIAAHIHPHGQDTWTVLSGMADYFQGNGIVRALREGEIAVARPGQVHGARNTGTEPFVFVSVVASANAGFVLAER
>CP028965.1|AXK68227.1|309981_310308_-|hypothetical-protein
MSRSRRKTPIVGHTTCGSEREDKKLWHQRWRTRERTALTSASPEALSAHLPLLENQASSVWSMGKDGRSYWPVKRQAATADRIANHKGRNPQERASLKKRLLRKWMSK
>CP028965.1|AXK68226.1|309484_309985_-|transposase
MKLSFHQHIALFWMIGAPGVFAPVIENAKRPDAGAVMAWGVAIVAVMILFTPLLLRCPPFRRWYGRTDALSERQRQALAERGLRRYYQTAFDDGYVPRVMPYVWRIIWTVGGLMAVTAVLPTNTGRPAFDALVVFSTWYPIGVMLLVFASRPLGRLIRQRAQERRK
>CP028965.1|AXK68225.1|309116_309488_-|hypothetical-protein
MSTSTIEALASAWARIAEEAEFPADYEGTATPQAHRASEAIQEQIRERIVATNDMRLFSLLHLLGQASLRMEQALWPEDYERMTREVEEALRQATDANARSYTHEEVMQAMQERIDRARDKPC
>CP028965.1|AXK68224.1|308565_309123_-|recombinase-family-protein
MLIGYARVSTQDQNLELQREALSKAGCKKVFEDKVSGTRADRPGLAKTLEMLREGDTLVVWKLDRLGRSVKQLVDLVGELHKHGVQFRSLTDSIDTGTPSGRFFFHVMASLAEMERELTVERTRAGLEVAKQLGRKGGRKPKMTDSKIESAKKLLASGVPPKDVAKNLGVSIPTLYRWVPASTHA
>CP028965.1|AXK68223.1|306089_308384_+|heavy-metal-translocating-P-type-ATPase
MSEGPDGALRDPVCGMSVTADSPFRSEHDGHPYFFCSASCQKKFRADPLRYVKPSTSTSVEAAPEGSIYTCPMHPEIRQDHPGNCPKCGMALEPLLPSLEDEENPELTDFRRRFWWTLPLTAVVFVLAMFGHRLGWMEASTQSWVELALSTPVVVWAGLPFFERCTRSFINRSPNMWTLIGLGTGTAYVYSVIATVVPGVFPEAFAAHGRVSVYFEAAAVIISLTLVGQLLELKARSQTSAAIKALLGLAPKTARRINADGTEEDVPLAHVHVGDLLRVRPGEKVPVDGVVTEGSSALDESMITGEPIPVSKRVGDHVIGATMNTSGSLIIKSEKVGSQTMLAQIVQMVAQAQRSRAPMQRMADKVAGVFVVAVVGVAILTFVAWGFFGPEPSWVYGLINAVAVLIIACPCALGLATPMSIMVASGKGASNGVLFRDAAAIENFRKVNTLIVDKTGTLTEGRPAFERAIGVNGYAEEDVLRLAASLDQGSEHPLAATIVDAARERRLAFEKVEHFESSTGIGVRGLVGSRNLALGNTTLMQADGIDVGTLTENSDTLRAQGASVMYLAVDGMLAGLLAVSDPVKATTPEALARLKEDGIRVVMATGDGVVTARAVATKLGIGEFHGEVKPADKLALVTKFQQEGKVVAMAGDGINDAPALAKADVGVAMGTGTDVAMSSAQVTLVKGDLRGIARARELSEATIGNMKQNLGFAFVYNALGVPLAAGVLYPFTGLLLSPMIAALAMSLSSASVITNALRLRNVKI
>CP028965.1|AXK68231.1|315569_315881_-|hypothetical-protein
MKHNAHLQLVTRDDTSDSSTTKPIARTAAQRQRAYRLRRKRAVIDAIGEEACASRVTMLALLGEGLAALDNSDTSTRLIESKRHCVRRVLQAIVTRYAIDLTD
>CP028965.1|AXK68232.1|315877_316711_-|hypothetical-protein
MNHEFDATRLSLLLNDLRLPAIKQIWSSFAERSDTEGWPAARLLMALAEHEIAERDRRRIERHLRDARLLPGKTLENFDFDAVPMVSRAHVSALCAGDGWLRNGANLILLGPSGGGKSHLSSAIGLSLLENGWKVLFARTTDLVQRLQVARRELSLESAINRLDRFDLLILDDFAYVSKDQAETSVLFELISARYEHRSLLLTANQPFGEWDRIFPDRAMTVAAVDRLVHHSTIFELNVESYRRRTALERKQQGPGRPASIATPNNVGVPPRPEDQQ
>CP028965.1|AXK68233.1|316707_318219_-|IS21-family-transposase
MPGRHVNDHQMRLYMKYRSKEQPTKAGARAGFSAATAYRIEQDPRPPSKKKAPRTRRRADPLAAIFDAEIVPLLQSAPGIRPVAVLDEMLRRHPDLPGNVRRTLERRIRDWRALHGEERDVMFRQVHEPGRLGLSDFTEMDSLGVTVAGVALDHRLYHFRLACSGFEHAHVILGGESYVALAEGLQNALWVLGGAPREHRSDSLSAAFRNLEREARDDLTTRYEALCAHYGMQPTRNNRGVAHENGSIESPHGHLKNAVRDALLLRGSKDFDDLDTYRRFIDEHVCRINARNGKRIDAERPQLQPLPPQRTTDYEQTRVYVSSTGGFVLRKVFYTVPSRLIGHRLRVRLYDDRLELFLGSTALMTLQRGRPGPSGKHGHVVNYRHIIHALRRKPMALLNLVYRDQVFPREAYRLTFERLCEQLPERAACKTMVELLSLAHERNCEAQLAQALEQCLADGQLPDLHALSSRFEAKPASLPQVNVQLPSLRDYEALLGLQMEVAA
>CP028965.1|AXK68234.1|318562_319585_+|IS21-family-transposase
MLTQEQSLEIRVLARQGHGIKAIARELGVSRNTVRRYLRGEATPPSYGPRAARPRKLDPYTQYLRDRIEAAHPHWIPATVLLREIREHGYTGGISQLKAFLAPLKVRPAEPVVRFETPPGKQMQADFTTIRRGRHPLKAFVATLGYSRATFVLFSEREDSPAWLRGLREAFVYFGGVPEEVLFDNAGTVVTERDAYGQGQHRWHPALASLADEFGFRPRLCRPYRARTKGKVERFNGYLKSSFVTPLAATLKTAGLLLDVDTANAHIGRWLAEVAQQRIHGTTGEKPEVRLAHERHSLMSLPRAFATPPAVTVKTADMVIPHESLQHPLSVYGALLEHAA
>CP028965.1|AXK68235.1|320374_321736_+|IS110-family-transposase
MASISNAPVRHRTVGIDLAISAVQVAQIFDDGRAIGKPIRFRLTSTDLRRFVSAIKSGVGADTPITAVMEPTGMAWFPVANWLQRAGIKVIRVKGQRVKALRKYLSEHAKTDAADAHVLGAIPGFGGRGLDPVHVPGPEQHSLQRLTKQRHRYQELVCSARRRVLDLIRWACPALEPVLPDTVTQLTLAILGELLDPRKVVAMRRDVLARFLSQHASGNHPKSGPFIDSLVEKLKAAAEETIELHGDSVDFTALQFEVAQEVEHLRLWDRHVRAIEREVEQIYQRVHPSDALRSIPGIGATLAPLLIGVLGYAKRFRNEDHIRGFCGMFPTRSSSGGIEKPGQRLTKSGSDRVKRALYIAADVARKIDPDLAAVYWRLMVNKGHHHKQAICAVATRLINRIYRVLKTGEPYVLRDQEGNSISVQEGKRIVAAQFKVPLEVRQSRRNQPMPEPA
>CP028965.1|AXK68236.1|323065_323680_+|recombinase-family-protein
MLIGYMRVSKADGSQATDLQRDALIANGVDPAHLYEDQASGKREDRPGLVSCLKALRPGDTLVVWKLDRLGRDLRHLINTVHDMTGRGIGLKVLTGHGAAIDTTTAAGKLVFGIFAALAEFERELIAERTIAGLASARARGRKGGRPFKMTAAKLRLAMAAMGQPETKVGDLCQELGITRQTLYRHISPKGELRLDGEKLLSQV
>CP028965.1|AXK68237.1|323746_324178_-|EamA-family-transporter
MINSAGWFYWALLSAIFAALTAIFAKVGIQGVDSDLATLIRTAIIIVVLSAFVAYTGKWANPLELSPKTWLFLGLSGLATGASWVCYFRALKIGDASKVAPVDKLSLVLVAVFAFAFLGERPSLREWSGISMVAGGVLLLAFK
>CP028965.1|AXK68238.1|324206_325559_-|two-component-sensor-histidine-kinase
MDGLKRRLNESVQLKLSFTLSLAILVVAVVAGVFSFLSAFDEAHELQDDVLRQVAQLMDRQRLLPAVPTTDIRLKDVDEESRVIVQRLGEVSPSTVGVDAGGVLPLPATLADGLHTLEVGGETFRVLVKTTASGERIAVAQESGFRNEIARDGALRTVMPFLILVPVLLLIVADLVRKMFQPIAALSKEIDQRAEQELHPVEDRHLPVEVRPFAVAINRLLARVGQSMESQRRFVADAAHELRSPLTAMSLQAERLAEAEMSSVARERLTVLRQGIERGRSLLDQLLTLAKAQSATDLPKSPVSVQSIYRRVLEDLMPLAEAKHIDIGVEGTLDAEVWASELDMIAVVKNLVDNAIRYTPEGGRVDLSVGVSEGKVVLRIQDSGPGIPLAERDRVFDPFYRTLGSEQIGSGLGLSIVQTIANRIGAEIRLDFSDQEKQTGLNVAVIAPMR
>CP028965.1|AXK68239.1|325534_326200_-|DNA-binding-response-regulator
MRVLLVEDDPMIGDAIQGALKDASYAADWVKDGQTALTTLGCQHYDLVLLDLGLPGKDGLEVLASIRAKDNPIPLLIITARDGLDDRLRGLDGGADDYVSKPFQMAELLARMRAVLRRKGGTAAPVLSNGVVTLDPATKEACANDGPQVQLSNREFSLLQALLVRPGAILSRSELEDRIYGWGEEVESNAVEYLIHALRRKLGGEVIKNVRGVGWMVSKGA
>CP028965.1|AXK68240.1|326222_326981_-|hypothetical-protein
MKTSTEHALAKVPEVTLGFWLIKIAATTLGETGGDAVSMSMNLGYLVGTAIFAAIFLAAVVAQVKAKDFHPFLYWTTIIATTTVGTTLADFADRSLGIGYAGGSSLLLALLLGSLFVWHRTLGSVSVSTVSSPKAEAFYWLTIMFSQTLGTALGDWTADTAGLGYTGAAVVFGGLLALVVAAYYWTSVSRTLLFWAAFILTRPLGAVVGDFLDKPVSAGGLALSRYSASAALLTFIVVAILLFRQRAARTAH

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Identity
CP028965_1	1.1\|71481\|57\|CP028965\|CRISPRCasFinder	71481-71537	57	NZ_CP028965	Burkholderia sp. IDO3 plasmid p1, complete sequence	71481-71537	1.0
CP028965_1	1.1\|71481\|57\|CP028965\|CRISPRCasFinder	71481-71537	57	NZ_CP028965	Burkholderia sp. IDO3 plasmid p1, complete sequence	229073-229129	1.0
CP028965_1	1.1\|71481\|57\|CP028965\|CRISPRCasFinder	71481-71537	57	NZ_CP028965	Burkholderia sp. IDO3 plasmid p1, complete sequence	315481-315537	1.0
CP028965_2	2.1\|229073\|57\|CP028965\|CRISPRCasFinder	229073-229129	57	NZ_CP028965	Burkholderia sp. IDO3 plasmid p1, complete sequence	71481-71537	1.0
CP028965_2	2.1\|229073\|57\|CP028965\|CRISPRCasFinder	229073-229129	57	NZ_CP028965	Burkholderia sp. IDO3 plasmid p1, complete sequence	229073-229129	1.0
CP028965_2	2.1\|229073\|57\|CP028965\|CRISPRCasFinder	229073-229129	57	NZ_CP028965	Burkholderia sp. IDO3 plasmid p1, complete sequence	315481-315537	1.0
CP028965_3	3.1\|315481\|57\|CP028965\|CRISPRCasFinder	315481-315537	57	NZ_CP028965	Burkholderia sp. IDO3 plasmid p1, complete sequence	71481-71537	1.0
CP028965_3	3.1\|315481\|57\|CP028965\|CRISPRCasFinder	315481-315537	57	NZ_CP028965	Burkholderia sp. IDO3 plasmid p1, complete sequence	229073-229129	1.0
CP028965_3	3.1\|315481\|57\|CP028965\|CRISPRCasFinder	315481-315537	57	NZ_CP028965	Burkholderia sp. IDO3 plasmid p1, complete sequence	315481-315537	1.0

1. spacer 1.1|71481|57|CP028965|CRISPRCasFinder matches to NZ_CP028965 (Burkholderia sp. IDO3 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

tgctgcggcgaggttgatgatgtcgatgttgattgacgctggcgagcgttgcctgcc	CRISPR spacer
tgctgcggcgaggttgatgatgtcgatgttgattgacgctggcgagcgttgcctgcc	Protospacer
*********************************************************

2. spacer 1.1|71481|57|CP028965|CRISPRCasFinder matches to NZ_CP028965 (Burkholderia sp. IDO3 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

tgctgcggcgaggttgatgatgtcgatgttgattgacgctggcgagcgttgcctgcc	CRISPR spacer
tgctgcggcgaggttgatgatgtcgatgttgattgacgctggcgagcgttgcctgcc	Protospacer
*********************************************************

3. spacer 1.1|71481|57|CP028965|CRISPRCasFinder matches to NZ_CP028965 (Burkholderia sp. IDO3 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

tgctgcggcgaggttgatgatgtcgatgttgattgacgctggcgagcgttgcctgcc	CRISPR spacer
tgctgcggcgaggttgatgatgtcgatgttgattgacgctggcgagcgttgcctgcc	Protospacer
*********************************************************

4. spacer 2.1|229073|57|CP028965|CRISPRCasFinder matches to NZ_CP028965 (Burkholderia sp. IDO3 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

ggcaggcaacgctcgccagcgtcaatcaacatcgacatcatcaacctcgccgcagca	CRISPR spacer
ggcaggcaacgctcgccagcgtcaatcaacatcgacatcatcaacctcgccgcagca	Protospacer
*********************************************************

5. spacer 2.1|229073|57|CP028965|CRISPRCasFinder matches to NZ_CP028965 (Burkholderia sp. IDO3 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

ggcaggcaacgctcgccagcgtcaatcaacatcgacatcatcaacctcgccgcagca	CRISPR spacer
ggcaggcaacgctcgccagcgtcaatcaacatcgacatcatcaacctcgccgcagca	Protospacer
*********************************************************

6. spacer 2.1|229073|57|CP028965|CRISPRCasFinder matches to NZ_CP028965 (Burkholderia sp. IDO3 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

ggcaggcaacgctcgccagcgtcaatcaacatcgacatcatcaacctcgccgcagca	CRISPR spacer
ggcaggcaacgctcgccagcgtcaatcaacatcgacatcatcaacctcgccgcagca	Protospacer
*********************************************************

7. spacer 3.1|315481|57|CP028965|CRISPRCasFinder matches to NZ_CP028965 (Burkholderia sp. IDO3 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

tgctgcggcgaggttgatgatgtcgatgttgattgacgctggcgagcgttgcctgcc	CRISPR spacer
tgctgcggcgaggttgatgatgtcgatgttgattgacgctggcgagcgttgcctgcc	Protospacer
*********************************************************

8. spacer 3.1|315481|57|CP028965|CRISPRCasFinder matches to NZ_CP028965 (Burkholderia sp. IDO3 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

tgctgcggcgaggttgatgatgtcgatgttgattgacgctggcgagcgttgcctgcc	CRISPR spacer
tgctgcggcgaggttgatgatgtcgatgttgattgacgctggcgagcgttgcctgcc	Protospacer
*********************************************************

9. spacer 3.1|315481|57|CP028965|CRISPRCasFinder matches to NZ_CP028965 (Burkholderia sp. IDO3 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

tgctgcggcgaggttgatgatgtcgatgttgattgacgctggcgagcgttgcctgcc	CRISPR spacer
tgctgcggcgaggttgatgatgtcgatgttgattgacgctggcgagcgttgcctgcc	Protospacer
*********************************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

56345 : 79278

Burkholderia_phage(25.0%)

integrase,transposase

attL 53121:53135|attR 81141:81155

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
53121:53135	attL	NA	NA	NA	NA
AXK68018.1\|56345_57566_+\|transposase	ISL3 family transposase	A9YX10	Burkholderia_phage	1.2e-228	93.6
AXK68019.1\|57587_57995_+	hypothetical protein	NA	NA	NA	NA
AXK68020.1\|58082_58646_+	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	1.1e-17	30.7
AXK68312.1\|58717_60520_+	hypothetical protein	NA	NA	NA	NA
AXK68021.1\|60651_61131_-	hypothetical protein	NA	NA	NA	NA
AXK68022.1\|61201_62131_-\|integrase	site-specific integrase	NA	NA	NA	NA
AXK68313.1\|62280_62673_-	DUF2471 family protein	NA	NA	NA	NA
AXK68023.1\|62771_63071_-	H-NS histone family protein	NA	NA	NA	NA
AXK68024.1\|63198_66348_-	error-prone DNA polymerase	A0A0K1Y9G6	Streptomyces_phage	7.5e-92	27.2
AXK68314.1\|66354_67815_-	DNA polymerase Y family protein	NA	NA	NA	NA
AXK68025.1\|67753_68470_-	translesion DNA synthesis-associated protein ImuA	NA	NA	NA	NA
AXK68315.1\|68853_69084_+	hypothetical protein	NA	NA	NA	NA
AXK68026.1\|69080_70259_+\|integrase	site-specific integrase	NA	NA	NA	NA
AXK68027.1\|71569_71881_-	hypothetical protein	NA	NA	NA	NA
AXK68028.1\|72404_73766_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	3.8e-08	19.3
AXK68029.1\|74564_76076_-\|transposase	IS21 family transposase	NA	NA	NA	NA
AXK68030.1\|76249_77329_+	hypothetical protein	NA	NA	NA	NA
AXK68031.1\|77325_79278_+\|integrase	integrase	NA	NA	NA	NA
81141:81155	attR	NA	NA	NA	NA

DBSCAN-SWA_2

195470 : 203131

uncultured_Caudovirales_phage(62.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXK68135.1\|195470_195965_+	arsenate reductase ArsC	A0A2H4J8A6	uncultured_Caudovirales_phage	2.7e-25	43.2
AXK68136.1\|195982_196477_+	arsenate reductase ArsC	A0A2H4J8A6	uncultured_Caudovirales_phage	4.5e-28	47.1
AXK68137.1\|196540_197614_+	arsenical-resistance protein	NA	NA	NA	NA
AXK68138.1\|197615_198848_+	MFS transporter	NA	NA	NA	NA
AXK68139.1\|198844_199267_+	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	2.6e-53	71.4
AXK68140.1\|199244_199982_+	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	3.0e-100	75.5
AXK68141.1\|200003_200432_+	GNAT family N-acetyltransferase	A0A2H4J155	uncultured_Caudovirales_phage	1.8e-09	32.0
AXK68330.1\|200521_200917_-	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	1.4e-11	42.1
AXK68142.1\|201068_202463_-	HAMP domain-containing protein	W8CYF6	Bacillus_phage	1.6e-17	24.7
AXK68143.1\|202459_203131_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	2.5e-29	34.7

DBSCAN-SWA_3

220487 : 321736

Salmonella_phage(11.76%)

integrase,transposase

attL 213775:213790|attR 258198:258213

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
213775:213790	attL	NA	NA	NA	NA
AXK68335.1\|220487_223403_-\|transposase	Tn3-like element IS1071 family transposase	A0A1B0V7H9	Salmonella_phage	1.4e-52	24.0
AXK68158.1\|223635_224193_+	hypothetical protein	NA	NA	NA	NA
AXK68159.1\|224229_224538_+	P-II family nitrogen regulator	NA	NA	NA	NA
AXK68160.1\|224604_225042_-	TetR family transcriptional regulator	NA	NA	NA	NA
AXK68161.1\|226390_227902_+\|transposase	IS21 family transposase	NA	NA	NA	NA
AXK68162.1\|227898_228732_+	hypothetical protein	A0A059NT77	Lactococcus_phage	1.6e-30	34.1
AXK68163.1\|228728_229040_+	hypothetical protein	NA	NA	NA	NA
AXK68164.1\|230283_232185_-	hypothetical protein	NA	NA	NA	NA
AXK68165.1\|232193_233378_-\|integrase	site-specific integrase	NA	NA	NA	NA
AXK68166.1\|234883_235885_-	hypothetical protein	NA	NA	NA	NA
AXK68167.1\|235859_238568_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	1.2e-50	27.5
AXK68168.1\|238848_239268_+	hypothetical protein	NA	NA	NA	NA
AXK68169.1\|240162_240348_-	hypothetical protein	NA	NA	NA	NA
AXK68170.1\|241107_241924_+\|transposase	IS5 family transposase	NA	NA	NA	NA
AXK68171.1\|242355_242607_-	hypothetical protein	NA	NA	NA	NA
AXK68172.1\|242569_242965_-	hypothetical protein	NA	NA	NA	NA
AXK68173.1\|243153_243822_-	hypothetical protein	NA	NA	NA	NA
AXK68174.1\|243854_244388_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AXK68175.1\|245836_246298_+	hypothetical protein	NA	NA	NA	NA
AXK68176.1\|246337_247285_-\|transposase	IS5-like element ISBvi6 family transposase	A0A1V0E8E1	Vibrio_phage	2.1e-58	43.3
AXK68177.1\|247371_248151_-	enoyl-[acyl-carrier-protein] reductase FabI	NA	NA	NA	NA
AXK68178.1\|248151_249330_-	acetate/propionate family kinase	NA	NA	NA	NA
AXK68179.1\|249341_250283_-	phosphate acetyltransferase	NA	NA	NA	NA
AXK68180.1\|250291_250537_-	hypothetical protein	NA	NA	NA	NA
AXK68181.1\|250533_252762_-	DUF3141 domain-containing protein	NA	NA	NA	NA
AXK68336.1\|252886_254347_-	TolC family protein	NA	NA	NA	NA
AXK68182.1\|254420_255548_-	ABC transporter permease	NA	NA	NA	NA
AXK68183.1\|255550_258379_-	ABC transporter ATP-binding protein/permease	A0A2H4PQG7	Staphylococcus_phage	1.6e-24	32.2
258198:258213	attR	NA	NA	NA	NA
AXK68184.1\|258382_259381_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
AXK68185.1\|260178_261210_+	AraC family transcriptional regulator	NA	NA	NA	NA
AXK68186.1\|261253_262117_-	AraC family transcriptional regulator	NA	NA	NA	NA
AXK68187.1\|262537_263716_-	acetate/propionate family kinase	NA	NA	NA	NA
AXK68337.1\|263772_264216_-	hypothetical protein	NA	NA	NA	NA
AXK68188.1\|264502_265252_-	acetoacetyl-CoA reductase	A0A0K0KVL6	Prochlorococcus_phage	5.6e-06	26.1
AXK68189.1\|265253_265706_-	hypothetical protein	NA	NA	NA	NA
AXK68190.1\|266002_267541_+\|transposase	IS3-like element ISBmu11 family transposase	A0A1B1P773	Bacillus_phage	2.8e-44	35.2
AXK68191.1\|267611_267785_+\|transposase	IS30 family transposase	NA	NA	NA	NA
AXK68192.1\|268039_268840_-	cytochrome c4	NA	NA	NA	NA
AXK68193.1\|268836_270462_-	cytochrome C oxidase subunit I	NA	NA	NA	NA
AXK68194.1\|270451_271039_-	cytochrome C oxidase subunit II	NA	NA	NA	NA
AXK68195.1\|271049_271250_-	hypothetical protein	NA	NA	NA	NA
AXK68196.1\|271259_272603_-	cytochrome c	NA	NA	NA	NA
AXK68197.1\|272599_273307_-	cytochrome c4	NA	NA	NA	NA
AXK68198.1\|274194_274833_+	DNA-binding response regulator	NA	NA	NA	NA
AXK68338.1\|275492_275792_-	H-NS histone family protein	NA	NA	NA	NA
AXK68199.1\|275893_276388_+	response regulator	NA	NA	NA	NA
AXK68200.1\|276834_277257_-	DUF3331 domain-containing protein	NA	NA	NA	NA
AXK68339.1\|277349_278423_-	rubrerythrin family protein	NA	NA	NA	NA
AXK68201.1\|278750_278978_+	hypothetical protein	NA	NA	NA	NA
AXK68202.1\|279532_279868_-	cupin domain-containing protein	NA	NA	NA	NA
AXK68203.1\|279897_280605_-	succinate dehydrogenase/fumarate reductase iron-sulfur subunit	NA	NA	NA	NA
AXK68204.1\|281639_282457_-\|transposase	IS5-like element ISBcen20 family transposase	NA	NA	NA	NA
AXK68341.1\|282712_283264_-	hypothetical protein	NA	NA	NA	NA
AXK68340.1\|283331_284309_-	ATP-binding protein	NA	NA	NA	NA
AXK68205.1\|284335_286321_-\|transposase	transposase	NA	NA	NA	NA
AXK68206.1\|286320_286953_-	hypothetical protein	NA	NA	NA	NA
AXK68207.1\|287111_290108_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	6.7e-82	26.5
AXK68208.1\|290104_290470_+\|transposase	transposase	NA	NA	NA	NA
AXK68209.1\|290828_291197_+	hypothetical protein	NA	NA	NA	NA
AXK68210.1\|291288_292581_+	TolC family protein	NA	NA	NA	NA
AXK68342.1\|292592_294122_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
AXK68211.1\|294118_297325_+	CusA/CzcA family heavy metal efflux RND transporter	S5VTK5	Leptospira_phage	1.4e-61	20.8
AXK68212.1\|297321_297672_+	RND transporter MFP subunit	NA	NA	NA	NA
AXK68343.1\|297745_299617_+	protein-disulfide reductase DsbD	NA	NA	NA	NA
AXK68213.1\|299668_300031_+	hypothetical protein	NA	NA	NA	NA
AXK68214.1\|300144_300444_+	hypothetical protein	NA	NA	NA	NA
AXK68215.1\|300497_300725_+	DUF2933 domain-containing protein	NA	NA	NA	NA
AXK68216.1\|300991_301549_+	hypothetical protein	NA	NA	NA	NA
AXK68217.1\|301582_301900_+	P-II family nitrogen regulator	NA	NA	NA	NA
AXK68218.1\|302337_302733_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
AXK68219.1\|303040_304597_+\|transposase	IS21 family transposase IS408	K4I413	Acidithiobacillus_phage	1.4e-160	55.1
AXK68220.1\|304613_305363_+	Insertion sequence IS408 ATP-binding protein	K4HZD4	Acidithiobacillus_phage	4.8e-82	60.7
AXK68221.1\|305493_305691_+	copper chaperone	NA	NA	NA	NA
AXK68222.1\|305858_306077_-	hypothetical protein	NA	NA	NA	NA
AXK68223.1\|306089_308384_+	heavy metal translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.1e-89	36.5
AXK68224.1\|308565_309123_-	recombinase family protein	A0A0C4UR34	Shigella_phage	1.5e-59	63.8
AXK68225.1\|309116_309488_-	hypothetical protein	NA	NA	NA	NA
AXK68226.1\|309484_309985_-\|transposase	transposase	NA	NA	NA	NA
AXK68227.1\|309981_310308_-	hypothetical protein	NA	NA	NA	NA
AXK68228.1\|310562_310919_-	cupin domain-containing protein	NA	NA	NA	NA
AXK68229.1\|311155_311542_-	DUF86 domain-containing protein	NA	NA	NA	NA
AXK68344.1\|311538_311829_-	nucleotidyltransferase	NA	NA	NA	NA
AXK68345.1\|312038_313757_+\|transposase	transposase	M4T586	Rhodobacter_phage	5.8e-06	25.7
AXK68230.1\|313759_314668_+\|transposase	transposase	NA	NA	NA	NA
AXK68231.1\|315569_315881_-	hypothetical protein	NA	NA	NA	NA
AXK68232.1\|315877_316711_-	hypothetical protein	A0A059NT77	Lactococcus_phage	7.4e-31	34.1
AXK68233.1\|316707_318219_-\|transposase	IS21 family transposase	NA	NA	NA	NA
AXK68234.1\|318562_319585_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	2.7e-83	48.4
AXK68235.1\|320374_321736_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	3.8e-08	19.3

DBSCAN-SWA_4

328412 : 387336

Acidithiobacillus_phage(22.22%)

integrase,transposase

attL 381658:381674|attR 395162:395178

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXK68243.1\|328412_329646_+\|transposase	IS3 family transposase	A0A1B0Z042	Pseudomonas_phage	1.1e-102	65.5
AXK68244.1\|330310_330646_-	peptidase M4	NA	NA	NA	NA
AXK68245.1\|330913_331471_+	recombinase family protein	A0A1B0V7I5	Salmonella_phage	2.6e-48	81.3
AXK68246.1\|333396_334920_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	1.1e-149	52.8
AXK68247.1\|334932_335700_+	AAA family ATPase	K4HZD4	Acidithiobacillus_phage	1.0e-71	55.0
AXK68248.1\|337019_337217_-\|transposase	transposase	NA	NA	NA	NA
AXK68249.1\|337725_338838_-\|transposase	IS1182-like element ISBuce1 family transposase	NA	NA	NA	NA
AXK68250.1\|339065_339932_+	phosphate/phosphite/phosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
AXK68251.1\|339931_340762_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	5.6e-23	33.6
AXK68252.1\|340761_342144_+	ABC transporter permease subunit	NA	NA	NA	NA
AXK68253.1\|342160_343165_+	hydroxyacid dehydrogenase	A0A1B1IVB5	uncultured_Mediterranean_phage	6.0e-19	27.7
AXK68254.1\|343169_344036_+	LysR family transcriptional regulator	NA	NA	NA	NA
AXK68255.1\|344384_345260_+\|integrase	integrase	S5W9T9	Leptospira_phage	1.5e-26	30.3
AXK68256.1\|345746_346277_-	hypothetical protein	NA	NA	NA	NA
AXK68257.1\|346414_349420_+\|transposase	Tn3 family transposase	NA	NA	NA	NA
AXK68258.1\|349406_349754_+\|transposase	transposase	NA	NA	NA	NA
AXK68259.1\|349750_350956_+	hypothetical protein	NA	NA	NA	NA
AXK68260.1\|351061_352759_+\|integrase	integrase	NA	NA	NA	NA
AXK68261.1\|354356_357293_-	restriction endonuclease subunit R	A7WKN6	Acidianus_filamentous_virus	3.9e-10	25.3
AXK68262.1\|358588_359596_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
AXK68263.1\|359623_360310_-	response regulator	NA	NA	NA	NA
AXK68264.1\|360309_362457_-	GHKL domain-containing protein	NA	NA	NA	NA
AXK68265.1\|364764_364962_-	hypothetical protein	NA	NA	NA	NA
AXK68266.1\|365108_365408_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
AXK68267.1\|365397_365643_-	type II toxin-antitoxin system ParD family antitoxin	NA	NA	NA	NA
AXK68268.1\|367649_368663_-	ATPase	NA	NA	NA	NA
AXK68269.1\|368821_369994_+\|integrase	integrase	NA	NA	NA	NA
AXK68270.1\|370557_370776_-	4-oxalocrotonate tautomerase family protein	NA	NA	NA	NA
AXK68271.1\|370834_372043_-	putative C-S lyase	NA	NA	NA	NA
AXK68272.1\|372423_373533_-	alkene reductase	NA	NA	NA	NA
AXK68273.1\|373685_374366_-	DsbA family oxidoreductase	NA	NA	NA	NA
AXK68346.1\|374435_374777_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
AXK68274.1\|374903_375467_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AXK68275.1\|375825_376380_+	OsmC family peroxiredoxin	NA	NA	NA	NA
AXK68276.1\|376525_377296_+	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	2.1e-08	26.6
AXK68277.1\|378094_378508_+	hypothetical protein	NA	NA	NA	NA
AXK68278.1\|379580_381017_-	hypothetical protein	NA	NA	NA	NA
AXK68279.1\|381013_382006_-	ATP-binding protein	NA	NA	NA	NA
381658:381674	attL	NA	NA	NA	NA
AXK68280.1\|382010_383993_-	hypothetical protein	NA	NA	NA	NA
AXK68347.1\|383989_384631_-	hypothetical protein	NA	NA	NA	NA
AXK68281.1\|385200_387336_+\|integrase	integrase	NA	NA	NA	NA
395162:395178	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP028963

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

385594 : 443129

uncultured_Caudovirales_phage(33.33%)

plate,protease,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXK64295.1\|385594_386119_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	7.4e-21	52.0
AXK64296.1\|386318_386795_+	hypothetical protein	NA	NA	NA	NA
AXK64297.1\|386988_387480_+	hypothetical protein	NA	NA	NA	NA
AXK64298.1\|387486_387828_-	hypothetical protein	NA	NA	NA	NA
AXK64299.1\|387824_388820_-	methyltransferase type 11	Q6V7M1	Burkholderia_virus	1.9e-49	44.8
AXK64300.1\|388968_389379_-	single-stranded DNA-binding protein	NA	NA	NA	NA
AXK64301.1\|389589_391569_-	helicase	A5A3V1	Burkholderia_phage	1.8e-43	41.0
AXK64302.1\|391940_392153_-	DNA-binding protein	NA	NA	NA	NA
AXK64303.1\|392277_394944_-	hypothetical protein	NA	NA	NA	NA
AXK64304.1\|395065_395326_-	hypothetical protein	NA	NA	NA	NA
AXK66999.1\|395590_396058_-	hypothetical protein	NA	NA	NA	NA
AXK64305.1\|396140_396413_-	hypothetical protein	NA	NA	NA	NA
AXK64306.1\|396498_396777_-	hypothetical protein	NA	NA	NA	NA
AXK64307.1\|396845_398237_-	DUF4102 domain-containing protein	NA	NA	NA	NA
AXK64308.1\|399465_399669_+	hypothetical protein	NA	NA	NA	NA
AXK64309.1\|399750_400551_-	cystine ABC transporter substrate-binding protein	NA	NA	NA	NA
AXK64310.1\|400910_404093_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	1.6e-57	28.2
AXK64311.1\|408771_409236_+	hypothetical protein	NA	NA	NA	NA
AXK64312.1\|410693_410807_+	hypothetical protein	NA	NA	NA	NA
AXK67000.1\|410849_410975_+	hypothetical protein	NA	NA	NA	NA
AXK67001.1\|411112_411463_+	hypothetical protein	NA	NA	NA	NA
AXK64313.1\|412070_412388_+	hypothetical protein	NA	NA	NA	NA
AXK64314.1\|412478_413261_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
AXK64315.1\|413257_414604_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
AXK64316.1\|414706_415318_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
AXK64317.1\|415694_416327_+	hypothetical protein	NA	NA	NA	NA
AXK64318.1\|416371_416887_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
AXK64319.1\|416902_418393_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
AXK64320.1\|418463_418967_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
AXK64321.1\|419029_419515_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
AXK64322.1\|419591_421427_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
AXK64323.1\|421390_422491_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
AXK64324.1\|422531_425201_+	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	2.9e-89	31.8
AXK64325.1\|425240_426362_+	type VI secretion system protein TssA	NA	NA	NA	NA
AXK64326.1\|426426_428988_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	4.0e-51	28.8
AXK64327.1\|428987_430010_+	DUF4123 domain-containing protein	NA	NA	NA	NA
AXK64328.1\|430023_430818_+	DUF3304 domain-containing protein	NA	NA	NA	NA
AXK64329.1\|431016_431796_+	DUF3304 domain-containing protein	NA	NA	NA	NA
AXK64330.1\|431788_434080_+	hypothetical protein	NA	NA	NA	NA
AXK64331.1\|434312_434888_-	DUF3592 domain-containing protein	NA	NA	NA	NA
AXK64332.1\|435027_435987_-	OmpA family protein	NA	NA	NA	NA
AXK64333.1\|435991_436981_-	type VI secretion system-associated protein TagF	NA	NA	NA	NA
AXK64334.1\|436977_440928_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
AXK64335.1\|441229_442075_-	M15 family peptidase	NA	NA	NA	NA
AXK64336.1\|442196_443129_+\|tail	phage tail protein	NA	NA	NA	NA

DBSCAN-SWA_2

2405511 : 2414652

Burkholderia_virus(85.71%)

integrase,holin

attL 2389533:2389550|attR 2420954:2420971

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2389533:2389550	attL	NA	NA	NA	NA
AXK65940.1\|2405511_2406795_+\|integrase	site-specific integrase	Q6J1Q2	Burkholderia_virus	1.0e-228	91.6
AXK65941.1\|2406919_2407108_+	hypothetical protein	NA	NA	NA	NA
AXK65942.1\|2407342_2407831_-	DUF2514 family protein	Q6J1Q4	Burkholderia_virus	4.3e-55	75.8
AXK65943.1\|2407827_2408322_-	glycoside hydrolase	Q6J1Q5	Burkholderia_virus	6.9e-77	87.2
AXK65944.1\|2408308_2408590_-\|holin	holin	Q6J1Q6	Burkholderia_virus	8.2e-27	67.7
AXK65945.1\|2408586_2408922_-\|holin	holin	Q6J1Q7	Burkholderia_virus	2.9e-39	77.5
AXK65946.1\|2408937_2411544_-	hypothetical protein	A0A2I7RDR8	Vibrio_phage	8.5e-25	35.7
AXK65947.1\|2411650_2412067_+	hypothetical protein	NA	NA	NA	NA
AXK65948.1\|2412063_2414652_-	hypothetical protein	Q6J1R0	Burkholderia_virus	0.0e+00	96.6
2420954:2420971	attR	NA	NA	NA	NA

DBSCAN-SWA_3

2419631 : 2450330

Burkholderia_virus(90.0%)

terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXK65949.1\|2419631_2420057_-	GNAT family acetyltransferase	Q6J1R4	Burkholderia_virus	4.1e-54	72.3
AXK65950.1\|2420046_2422350_-	hypothetical protein	Q6J1R5	Burkholderia_virus	0.0e+00	85.4
AXK65951.1\|2422358_2422982_-	hypothetical protein	Q6J1R6	Burkholderia_virus	1.2e-97	84.5
AXK65952.1\|2422993_2423218_-	hypothetical protein	Q6J1R7	Burkholderia_virus	6.4e-14	57.6
AXK65953.1\|2423281_2423692_-	hypothetical protein	Q6J1R8	Burkholderia_virus	4.5e-50	74.1
AXK65954.1\|2423754_2424747_-	hypothetical protein	Q6J1R9	Burkholderia_virus	3.4e-152	77.3
AXK65955.1\|2424756_2425509_-	hypothetical protein	Q6J1S0	Burkholderia_virus	4.4e-83	81.7
AXK65956.1\|2425556_2425901_-	hypothetical protein	A2I2Y8	Vibrio_virus	2.3e-31	63.8
AXK65957.1\|2425913_2426258_-	hypothetical protein	Q6J1S1	Burkholderia_virus	9.1e-52	91.2
AXK65958.1\|2426254_2426551_-	hypothetical protein	NA	NA	NA	NA
AXK65959.1\|2426550_2428200_-	hypothetical protein	Q6J1S2	Burkholderia_virus	6.1e-287	90.0
AXK65960.1\|2428196_2428424_-	hypothetical protein	Q6J1S3	Burkholderia_virus	7.6e-15	73.9
AXK65961.1\|2428730_2430152_-	TerL	Q6J1S4	Burkholderia_virus	2.6e-278	95.3
AXK65962.1\|2430292_2431021_-\|terminase	terminase small subunit	Q6J1S5	Burkholderia_virus	8.5e-116	86.4
AXK65963.1\|2431017_2431320_-	hypothetical protein	Q6J1S6	Burkholderia_virus	5.9e-47	95.0
AXK67144.1\|2431545_2433858_-	hypothetical protein	Q6J1N1	Burkholderia_virus	0.0e+00	85.0
AXK67145.1\|2434284_2434503_-	hypothetical protein	Q6J1N2	Burkholderia_virus	9.5e-31	91.5
AXK65964.1\|2434585_2435323_+	helix-turn-helix domain-containing protein	Q6J1N3	Burkholderia_virus	1.9e-107	77.0
AXK65965.1\|2435781_2436396_+	hypothetical protein	Q6J1N6	Burkholderia_virus	4.6e-38	81.0
AXK65966.1\|2436392_2437775_+	DUF2800 domain-containing protein	Q6J1N8	Burkholderia_virus	1.1e-225	88.0
AXK65967.1\|2437771_2437981_+	hypothetical protein	NA	NA	NA	NA
AXK65968.1\|2438009_2438615_+	DUF2815 family protein	Q6J1N9	Burkholderia_virus	5.1e-98	88.9
AXK67146.1\|2438823_2439087_+	hypothetical protein	A1YZX0	Burkholderia_virus	3.4e-14	50.6
AXK65969.1\|2439083_2439434_+	hypothetical protein	NA	NA	NA	NA
AXK65970.1\|2439423_2439783_+	hypothetical protein	Q6J1P3	Burkholderia_virus	5.0e-61	92.4
AXK65971.1\|2439839_2440574_+	site-specific DNA-methyltransferase	O03956	Myxococcus_phage	1.4e-57	51.6
AXK65972.1\|2440570_2441638_+	DNA cytosine methyltransferase	Q6J1P4	Burkholderia_virus	8.0e-123	63.2
AXK65973.1\|2441656_2443786_+	DNA polymerase I	Q6J1P5	Burkholderia_virus	0.0e+00	91.6
AXK65974.1\|2443788_2444067_+	hypothetical protein	NA	NA	NA	NA
AXK67147.1\|2444175_2444739_+	hypothetical protein	Q6J1P6	Burkholderia_virus	2.7e-77	83.8
AXK67148.1\|2445446_2445629_+	hypothetical protein	Q6J1P8	Burkholderia_virus	2.0e-21	83.3
AXK65975.1\|2445625_2447086_+	ATP-dependent helicase	Q6J1P9	Burkholderia_virus	1.0e-261	94.1
AXK65976.1\|2447112_2447328_+	DNA-binding protein	Q6J1Q0	Burkholderia_virus	2.1e-22	84.8
AXK65977.1\|2447413_2448190_+	exodeoxyribonuclease III	NA	NA	NA	NA
AXK65978.1\|2448215_2450330_-	S9 family peptidase	A0A1V0SHT0	Klosneuvirus	1.1e-30	38.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP028962

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP028965

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. CP028963

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection