CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP012216	Campylobacter jejuni strain CJ074CC443, complete genome	1 crisprs	cas2,cas1,cas9,csa3,DEDDh,WYL,c2c9_V-U4	2	7	0	0

1. CP012216

CRISPR-Cas detection and classification

Crispr_ID: CP012216_1

• CRISPR_ID: CP012216_1
• CRISPR_location: 546265-546499
• CRISPR_type: TypeII
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: cas2,cas1,cas9

Consensus repeat of CP012216_1

Consensus_repeat	Method
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	PILER-CR
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	CRT
ATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	CRISPRCasFinder

spacers of CP012216_1

>1.1|546302|29|CP012216|PILER-CR,CRT
ATAGAAATTACTACAGCACAAGCTTATAC
>1.2|546368|29|CP012216|PILER-CR,CRT
CAAAAAACTTGTATTTTTTATCAAAAAAC
>1.3|546434|29|CP012216|PILER-CR,CRT
TGGAGTTGAAAGAGTTAATAATACCAATA
>1.4|546302|30|CP012216|CRISPRCasFinder
ATAGAAATTACTACAGCACAAGCTTATACA
>1.5|546368|30|CP012216|CRISPRCasFinder
CAAAAAACTTGTATTTTTTATCAAAAAACT
>1.6|546434|30|CP012216|CRISPRCasFinder
TGGAGTTGAAAGAGTTAATAATACCAATAT

CRISPR arrays and Neighbor proteins around CP012216_1

CRISPR arrays

The CRISPR arrays of CP012216_1

>merge|CP012216|1|546265-546499|PILER-CR,CRT,CRISPRCasFinder
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATATAGAAATTACTACAGCACAAGCTTATACAATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATCAAAAAACTTGTATTTTTTATCAAAAAACTATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATTGGAGTTGAAAGAGTTAATAATACCAATATATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT

>CP012216|1|1|546265-546499|PILER-CR
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	ATAGAAATTACTACAGCACAAGCTTATAC
AATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	CAAAAAACTTGTATTTTTTATCAAAAAAC
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	TGGAGTTGAAAGAGTTAATAATACCAATA
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT

>CP012216|1|1|546265-546499|CRT
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	ATAGAAATTACTACAGCACAAGCTTATAC
AATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	CAAAAAACTTGTATTTTTTATCAAAAAAC
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	TGGAGTTGAAAGAGTTAATAATACCAATA
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT

>CP012216|1|1|546266-546499|CRISPRCasFinder
ATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	ATAGAAATTACTACAGCACAAGCTTATACA
ATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	CAAAAAACTTGTATTTTTTATCAAAAAACT
ATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	TGGAGTTGAAAGAGTTAATAATACCAATAT
ATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP012216.1|AXL40077.1|544505_544952_+|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl|CDD|223391
CP012216.1|AXL40075.1|542740_544282_+|bilirubin-oxidase	unknown	unknown	gnl|CDD|225043
CP012216.1|AXL40078.1|544955_546146_+|molybdenum-cofactor-biosynthesis-protein-MoaA	unknown	unknown	gnl|CDD|223380
CP012216.1|AXL40087.1|555693_556731_-|DNA-binding-protein	unknown	unknown	gnl|CDD|224292
CP012216.1|AXL40072.1|539743_540286_-|formate-dehydrogenase	unknown	unknown	gnl|CDD|239153
CP012216.1|AXL40073.1|540285_540477_-|Tat-pathway-signal-protein	unknown	unknown	gnl|CDD|236534
CP012216.1|AXL40074.1|541468_542617_-|carboxynorspermidine-decarboxylase	unknown	unknown	gnl|CDD|273414
CP012216.1|AXL40081.1|547944_550908_-|CRISPR-associated-protein	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|226044
CP012216.1|AXL40071.1|537481_539695_-|formate-dehydrogenase	unknown	unknown	gnl|CDD|239153
CP012216.1|AXL41190.1|540451_541153_-|hypothetical-protein	unknown	unknown	gnl|CDD|225916
CP012216.1|AXL40088.1|556795_557245_-|DNA-polymerase-III-subunit-beta	unknown	unknown	gnl|CDD|223854
CP012216.1|AXL40070.1|536843_537485_-|formate-dehydrogenase	unknown	unknown	gnl|CDD|319893
CP012216.1|AXL40083.1|552589_553579_-|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl|CDD|235439
CP012216.1|AXL40080.1|547067_547958_-|CRISPR-associated-protein-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|187851
CP012216.1|AXL40085.1|554241_554991_+|diaminopimelate-epimerase	unknown	unknown	gnl|CDD|234768
CP012216.1|AXL40082.1|551114_552569_+|C4-dicarboxylate-ABC-transporter	unknown	unknown	gnl|CDD|225611
CP012216.1|AXL40076.1|544283_544505_+|molybdenum-cofactor-biosynthesis-protein-MoaD	unknown	unknown	gnl|CDD|340452
CP012216.1|AXL40086.1|554965_555697_+|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase	unknown	unknown	gnl|CDD|225539
CP012216.1|AXL40079.1|546643_547075_-|CRISPR-associated-protein-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|226043
CP012216.1|AXL40084.1|553639_554245_+|dephospho-CoA-kinase	unknown	unknown	gnl|CDD|234620

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP012216.1|AXL40081.1|547944_550908_-|CRISPR-associated-protein	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	0	1178.6	69.9
CP012216.1|AXL40079.1|546643_547075_-|CRISPR-associated-protein-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	5e-59	192.3	1.5
CP012216.1|AXL40080.1|547067_547958_-|CRISPR-associated-protein-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	1.4e-98	324.1	9.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP012216.1|AXL40077.1|544505_544952_+|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl|CDD|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	4.04507e-43
CP012216.1|AXL40075.1|542740_544282_+|bilirubin-oxidase	gnl|CDD|225043	COG2132, SufI, Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism].	9.71152e-120
CP012216.1|AXL40078.1|544955_546146_+|molybdenum-cofactor-biosynthesis-protein-MoaA	gnl|CDD|223380	COG0303, MoeA, Molybdopterin biosynthesis enzyme [Coenzyme metabolism].	7.93699e-140
CP012216.1|AXL40087.1|555693_556731_-|DNA-binding-protein	gnl|CDD|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	7.93254e-34
CP012216.1|AXL40072.1|539743_540286_-|formate-dehydrogenase	gnl|CDD|239153	cd02752, MopB_Formate-Dh-Na-like, Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the major electron donor to the nitrate respiratory chain. Also included in this CD is the Desulfovibrio gigas tungsten formate dehydrogenase, DgW-FDH. In contrast to Fdh-N, which is a functional heterotrimer, DgW-FDH is a heterodimer. The DgW-FDH complex is composed of a large subunit carrying the W active site and one [4Fe-4S] center, and a small subunit that harbors a series of three [4Fe-4S] clusters as well as a putative vacant binding site for a fourth cluster. The smaller subunit is not included in this alignment. Members of the MopB_Formate-Dh-Na-like CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	9.0213e-62
CP012216.1|AXL40073.1|540285_540477_-|Tat-pathway-signal-protein	gnl|CDD|236534	PRK09476, napG, quinol dehydrogenase periplasmic component; Provisional.	0.00537271
CP012216.1|AXL40074.1|541468_542617_-|carboxynorspermidine-decarboxylase	gnl|CDD|273414	TIGR01047, carboxynorspermidine_decarboxylase, carboxynorspermidine decarboxylase. This protein is related to diaminopimelate decarboxylase. It is the last enzyme in norspermidine biosynthesis by an unusual pathway shown in Vibrio alginolyticus. [Central intermediary metabolism, Polyamine biosynthesis].	0
CP012216.1|AXL40081.1|547944_550908_-|CRISPR-associated-protein	gnl|CDD|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
CP012216.1|AXL40071.1|537481_539695_-|formate-dehydrogenase	gnl|CDD|239153	cd02752, MopB_Formate-Dh-Na-like, Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the major electron donor to the nitrate respiratory chain. Also included in this CD is the Desulfovibrio gigas tungsten formate dehydrogenase, DgW-FDH. In contrast to Fdh-N, which is a functional heterotrimer, DgW-FDH is a heterodimer. The DgW-FDH complex is composed of a large subunit carrying the W active site and one [4Fe-4S] center, and a small subunit that harbors a series of three [4Fe-4S] clusters as well as a putative vacant binding site for a fourth cluster. The smaller subunit is not included in this alignment. Members of the MopB_Formate-Dh-Na-like CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	3.96161e-154
CP012216.1|AXL41190.1|540451_541153_-|hypothetical-protein	gnl|CDD|225916	COG3381, TorD, Uncharacterized component of anaerobic dehydrogenases [General function prediction only].	0.00045239
CP012216.1|AXL40088.1|556795_557245_-|DNA-polymerase-III-subunit-beta	gnl|CDD|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	5.92874e-51
CP012216.1|AXL40070.1|536843_537485_-|formate-dehydrogenase	gnl|CDD|319893	cd16371, DMSOR_beta_like, uncharacterized subfamily of DMSO Reductase beta subunit family. This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.	6.18245e-57
CP012216.1|AXL40083.1|552589_553579_-|phosphoribosylformylglycinamidine-cyclo-ligase	gnl|CDD|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
CP012216.1|AXL40080.1|547067_547958_-|CRISPR-associated-protein-Cas1	gnl|CDD|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	7.41783e-121
CP012216.1|AXL40085.1|554241_554991_+|diaminopimelate-epimerase	gnl|CDD|234768	PRK00450, dapF, diaminopimelate epimerase; Provisional.	7.83442e-91
CP012216.1|AXL40082.1|551114_552569_+|C4-dicarboxylate-ABC-transporter	gnl|CDD|225611	COG3069, DcuC, C4-dicarboxylate transporter [Energy production and conversion].	6.3934e-72
CP012216.1|AXL40076.1|544283_544505_+|molybdenum-cofactor-biosynthesis-protein-MoaD	gnl|CDD|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	3.22446e-11
CP012216.1|AXL40086.1|554965_555697_+|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase	gnl|CDD|225539	COG2992, Bax, Uncharacterized FlgJ-related protein [General function prediction only].	1.57422e-98
CP012216.1|AXL40079.1|546643_547075_-|CRISPR-associated-protein-Cas2	gnl|CDD|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	6.96465e-59
CP012216.1|AXL40084.1|553639_554245_+|dephospho-CoA-kinase	gnl|CDD|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	1.78546e-68

Protein sequences

>CP012216.1|AXL40078.1|544955_546146_+|molybdenum-cofactor-biosynthesis-protein-MoaA
MLMSYEESLKILHSHIKTYEKIEKIALTECLGRILAQDIKAPKNQPEFPTSAMDGYAIKFEDQDKPLKILGITPAGTMPQFSVQNGTCVKTFTGSLMSEGSDTLVPVENICIENDTLFIEKKVPQAFAVRAVGENYKKDEILLKKGTKLNYSEIALLAELGFFHISVFIKPIVGVLSSGSEIKDLGEALENPAQIRSSNHIAIANLAKNLNCDTRVFPLLKDDEKATFSTLESALQSCDILVTTGGVSMGDFDFLKKAIKEYEIIIDKADIKPGRHIKIAKANEKFIIALPGFPYSAMVMFNLYAREILNSWLLQPKDYICKAFLQGSYKKKTPYLEFVACNIKFENGRILANLEGKKEGSSAIINNLNNKAALMVAPKECEILENESLVDIIFMP
>CP012216.1|AXL40077.1|544505_544952_+|molybdenum-cofactor-biosynthesis-protein-MoaE
MEHFTLYQGSLDISKIYSQWYEFAKDKNCGALLTFCGIVREEGGIEALSFDIYEPLLKKWFDEWQKRVDFDGISLLFAHSIGDVAIHESSYFAGILSKQRKLGLKLLNEFVEDFKASAPIWKYDVINKERIYAKERSTKLCGAGLLKG
>CP012216.1|AXL40076.1|544283_544505_+|molybdenum-cofactor-biosynthesis-protein-MoaD
MVKVEFLGPINKENLELKVKNLKELKEILQKDESLKEWLELCAVSLNDEIIFDENTKLKDGDKIALLPPVCGG
>CP012216.1|AXL40075.1|542740_544282_+|bilirubin-oxidase
MNRRNFLKFNALTLASMGVAYANPMHDMHSMHKNHSINHDLDTSFINFAPKNLKLLDPKQFPQGEILKALPLLKNESKEKNIFRATLEIKENHIELIKGKKTLFYTYNGLVPAPKIEVFEGDKLEILVKNKLKEATTIHWHGVPVPPDQDGSPHDPILAGEERIYRFKIPQDSAGTYWYHPHPHYTASKQVFMGLAGAFVIKAKKDALSHLKERDLMISDLRLDENAQIPNNNLNDWLNGREGEFVLINGQFKPQIKLATNERIRIYNATAARYLNLRIQGAKFILVGTDGGLIEKTIYKEELFLSPASRAEVLIDAPKDGNFKLESAYYDRDKMMVKEEPNTLFLANINLKKENVELPKNLKIFKPSEEPKEFKEIIMSEDHMQMHGMMGKSESELKIALASMFLINGKSYDLKRIDLSSKLGVVEDWIVINKSHMDHPFHIHGTQFELISSKLNGKVQKAEFRALRDTINVRPNEELRLRMKQDFKGLRMYHCHILEHEDLGMMGNLEVKE
>CP012216.1|AXL40074.1|541468_542617_-|carboxynorspermidine-decarboxylase
MFYEKIQTPAYILEEDKLRKNCELLASVGEKSGAKVLLALKGFAFSGAMKIVGEYLKGCTCSGLWEAKFAKEYMDKEIHTYSPAFKEDEIGEIASLSHHIVFNSLAQFHKFQAKTQKNSLGLRCNVEFSLAPKELYNPCGRYSRLGIRAKDFENVDLSTIEGLHFHALCEESADALEAVLKAFEEKFGKWIGQMKWVNFGGGHHITKKGYDVEKLIALCKNFSDKYGVQVYLEPGEAVGWQTGNLVASVVDIIENEKQIAILDTSSEAHMPDTIIMPYTSEVLNARMLATRENEKISDLKESEFSYLLTGNTCLAGDVMGEYAFDKKLKIGDKIVFLDQIHYTIVKNTTFNGIRLPNLMLLDRKNELQMIREFSYKDYSLRN
>CP012216.1|AXL41190.1|540451_541153_-|hypothetical-protein
MDLEKLRLARSLYYQCLGELFVFSFSEERLSKLQEYLKTMQECLFDENLKSNFDILLKHLDDENSIQAFFKEYDLLFLSLKNSIPTTFSYIEEGFENSNPLLCVRQILVKSKIRRNEKFFKESEDSVGFCLLLMSEFLRQNEDDLAKELFEKVINKSIDEFLGDVFMNKNANLYKEIASIASAFMEFERLCFEVEKPAKINSKKVQNDLSRSEFLRREVNKQRRTREKSQGIS
>CP012216.1|AXL40073.1|540285_540477_-|Tat-pathway-signal-protein
MKNRREFLKKSAFALGAAGVLGSTTLALAKDEERKDLVKGKSKKKEVLFQRSANWEKYYIKAE
>CP012216.1|AXL40072.1|539743_540286_-|formate-dehydrogenase
MSSVGENIKLTRRSFLKMAALSSLATPLLARSETLREASADELKEAYEGSKKVKTVCTACSVGCGIIAEVQNGVWVRQEIAQDHPVSSGGHCCKGSDMIDMVRSHVRLKYPMKKENGEWKRISYEQALSEIGEKLAAYRKENPESVMFLGSAKLNNEQAYYIRKFAAFFGTNNVDHQARI
>CP012216.1|AXL40071.1|537481_539695_-|formate-dehydrogenase
MTNHLGDIQRSKCIIIIGANPAVNHPVGFRHFLKAKEKGAKLIVVDPRFTKSAAKADIYARIRPGTDIAFMYGMLKIIFDEGLEDTKYLDERVFGIDKIREEAAKWTAEEVENVTGISKELLVQITHEVAKNKPTTLIWAMGLTQHTVGTSNTRLAPIVQMVLGNIGKFGGGVNILRGHDNVQGASDMACLSENLPGYYPLNEATWRYYAKIWGVDYEWLLGNFVSKDWMHKTGLSLARWWAAALNGKDGNDAIDNAGTPLKALVVMGNGITSTAQQVKVKEGLEALELLVLADPFVNEAGIIAERKDGIYLLPAATQFETSGSVTATNRSGQWRFKVVDPLYESMEDQEILFELAKKLGFYEDFTKTLRDEKGEIVWPENATREIAKAVRSIGLNGWSPERLKKHTLYWDKFDEVTLEGKDEVAGEYYGLPWPCWSDKHPGSPVLYNTDIEVAKGGMGFRNNFGLEYEGESLLAKNAPLNSPIDTGYPQITKDNIEKVLGITLSAQEKEKMGSTWSYDDSNIIATKCIEKGIVPYGNAKARAVVWTFKDKIPLHREPLHSPRNDLVQKYPSFEDQKALYRVDTKFVSVQQAKDYSKEFPLNLVTARLVNLNGAGMENRASMYLTRLTPEMFCEINPQLAKEQDIKAGDMIWVHSPEGTKIHVRVKVNPGVAKDMIFLPFHFTGVMQGVDLTHNFPEGTKPYASGESANTVTNYGYDIMCQIPETKGGLCRISKDGK
>CP012216.1|AXL40070.1|536843_537485_-|formate-dehydrogenase
MSKVNFANLEKERLKFFCDNERCIDCNGCAVACDEAHELPIHIRRRRVITLNEGIQGKEVSTSISCMHCDDAPCSIVCPVDCFYIRADGIVLHDKEICIGCGYCLYACPFGAPQFPKDSVFGNKGIMDKCTMCAGGPEATNSEKERELYGQNRIAEGKVPVCAAMCSTKALLVGESSKIEEIYHNRLMNRNYGIPNPSESLEWKIAYTGKERL
>CP012216.1|AXL40079.1|546643_547075_-|CRISPR-associated-protein-Cas2
MIEDKFMRVLLMFDVPTKSKKEQKLASKFRNNLIKLGYFMLQFSVYMRICKGLSSAKSSIENVKKILPPYGNVRALIITEKQFDKMELLLGGIVFNEKVNNETNLTLFDIDSHGEFKYKNSNNEEIQLNKKQEKYHQQNLFEF
>CP012216.1|AXL40080.1|547067_547958_-|CRISPR-associated-protein-Cas1
MSYDEAFKTLLISSNAKLNLELNHLVIKQDENIAKLFLKDINIIVLESLQASLSSALFNAFARHKIILLTCDETHSINGIFTPFLGHFQSAKIAKEQINVSAQKKAILWQKIIKNKILNQAFVLKKHNKIEQSNELINLAKKVSLNDSKNIEAVAAALYFKTLFGTSFSRDELCFENSALNYGYAIIRACIIRAVCISGLLPWLGIKHDNIYNSFALCDDLIEVFRASVDDCVLKLKGESEFLSKDDKRALIGNLQSKINFDGQNYPLNRAINHYVANFKNALLYEDELKIVKFDD
>CP012216.1|AXL40081.1|547944_550908_-|CRISPR-associated-protein
MARILAFDIGISSIGWAFSENDELKDCGVRIFTKAENPKTGESLALPRRLARSARKRLARRKARLNHLKHLIANEFKLNYEDYQSFDESLAKAYKGSLISPYELRFRALNELLSKQDFARVILHIAKRRGYDDIKNSDDKEKGAILKAIKQNEEKLANYQSVGEYLYKEYFQKFKENSKEFTNVRNKKESYERCIAQSFLKDELKLIFKKQREFGFSFSKKIEEEVLSVAFYKRALKDFSHLVGNCSFFTDEKRAPKNSPLAFMFVALTRIINLLNNLKNTEGILYTKDDLNALLNEVLKNGTLTYKQTKKLLGLSDDYEFKGEKGTYFIEFKKYKEFIKALGDHSLSQDDLNEIAKDITLIKDEIKLKKALAKYDLNQNQIDSLSKLEFKDHLNISFKALKLITPLMLEGKKYDEACNELNLKVAINEDKKDFLPAFNETYYKDEVTNPVVLRAIKEYRKVLNALLKKYGKVHKINIELAREVGKNYSQRAKIEKEQNENYKAKKDAELECEKLGLKINSKNILKLRLFKEQKEFCAYSGEKIKISDLQDEKMLEIDHIYPYSRSFDDSYMNKVLVFTKQNQEKLNQTPFEAFGNDSAKWQKIEVLAKNLPTKKQKRILDKNYKDKEQKDFKDRNLNDTRYIARLVLNYTKDYLDFLPLSDDENTKLNDTQKGSKVHVEAKSGMLTSALRHTWGFSAKDRNNHLHHAIDAVIIAYANNSIVKAFSDFKKEQESNSAELYAKKISELDYKNKRKFFEPFSGFRQKVLDKIDEIFVSKPERKKPSGALHEETFRKEEEFYQSYGGKEGVLKALELGKIRKVNGKIVKNGDMFRVDIFKHKKTNKFYAVPIYTMDFALKVLPNKAVARSKKGEIKDWILMDENYEFCFSLYKDSLILIQTKDMQEPELVYFNAFTSSTVSLIVSKHDNKFETLSKNQKILFKNANEKEVIAKSIGIQNLKVFEKYIVSALGEVTKAEFRQREDFKNELR
>CP012216.1|AXL40082.1|551114_552569_+|C4-dicarboxylate-ABC-transporter
MPIFMICSTLLAVIVVAYYILKKYNPIFVFFLSGIILLIFAFYITGTPIPKAPSREHASFLNVLLDSYAFITATFKSQLSGVGLIIMSVAGFATYMKHINASAKLAFLANKPLGKIKNKYLILSGTFIVGMALKIVISSYAGLLLLLLACIYPVLISLKIRPITAVCVLSLIALDYGPKDGNSINMADMVGQSDNVVGLFLNYQIYSVIAYVMVIAILIPFYFAWIDKRDKEKGVLNDEVEIPQIIDPKCPTFYILFPWLPVVFLFIAYFFTIKLDVVTANFVSISLVFLVEFARHRNARKLGEDMMVILKAMAEIFISVVSIIIAAGVFAEGIKALGGVNILANAVSSLGTGNFAWFGILLSIAILSFLVYFATVIMGSGIAAFNAFGKLAPDIAKKLGVAPITLVLPIEIASCLGRAASPIAGGIIALAGFAKVAPMDIIKRTTPLLLIAMLVNVLVAFYLAQTNPLPKEQNTTKIELKIQK
>CP012216.1|AXL40083.1|552589_553579_-|phosphoribosylformylglycinamidine-cyclo-ligase
MKISYEDAGVSIDNGNAFVEAIKPLVKETFNDNVVGGIGSFAGAFRMPSGFKKPVILGATDGVGTKLRLAIDAKKYDTIGQDLVAMCVNDLICNFATPLFFLDYYATAKLEVEVAKAVVSGIAKGCKMANCALIGGETAEMPGMYVKDDFDLAGFAVGMAEEDEIDRSKFVKNGDILLALPSSGLHSNGYSLARKVLFESLKLKFDDKIEGKNLIDILLEPTRIYVRDFLTLKPYISALAHITGGGLVENLPRVLPRGMGATIRKHHLKTPEIFYTIGQAVEESEMYRSFNMGVGLVMVVDPSNVSKVLENSDAFIIGEICINEGIVLE
>CP012216.1|AXL40084.1|553639_554245_+|dephospho-CoA-kinase
MKNAFFVTASIACGKSTFIEIANSLDFKSISADKIAHKILDENALELEKIFSPFSLKNLLTKEKKIDRKILGEIVFNNKEAKKILENFTHPKIRAKILEQIQILDKENKAFFVEIPLFFESGAYENLGKVIVIYTPKELSLKRIMQRDKLSLEAAKARLDSQIDIEEKLKKADFIIKNTNSYADFRQECVKVIQEISKGKM
>CP012216.1|AXL40085.1|554241_554991_+|diaminopimelate-epimerase
MKFYKYCASGNDFVITNADRKEDRSTLAKELCNRYEGIGGDGFIVILPHEKYDFEWEFYNNDGSRAAMCGNGSRAAAHFAHHINKINPNMSFLTSAGIIKAKVNQDKVEVSLGKIKSVQNTFEELGKTWQLCDTGVPHLVHFCQNLDEFDTILCQKMRQKYNANVNFVKILDENHLKVRTYERGVEDETLACGTGMGACFYLAFLNKKVQNKVKITPKSGEEVGFAYKNEELFFEGKVKYCFEANYNFS
>CP012216.1|AXL40086.1|554965_555697_+|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase
MKPIIIFLSLFLIPLFADDLKNGFGEEYYKLDIDQKRQIFFIKMNEMFDQSFKKIEQERAFIEAFFKDAYKTGFRTSNQTNLEKLITIKNKYRIENLYDFAEYKKRIQKIPKSMGIAQALVESATGTSRFAREANNLFGEWTWGEKGLIPDLRHPDKKHKIKIFDSLQDSVYSYVLNLNRHFAYEKFRDARAKFASEGKEITGLEAIKTLDSYSERKGYYINLITKIIKRYNLEKYDTNSNNT
>CP012216.1|AXL40087.1|555693_556731_-|DNA-binding-protein
MKVLNFFYENHPKFEVSYERKNQISKPNIIIKGPRFCGKKTLIFNFLSQFKASEILFLDLYDTRFEKQSLERLADFLNENLQIKILCLYNLDFIPNLEKIKIPIILSTNIKDLNINGFEELELDYFDFEEFISVSKKNLPINNLVGLFLQSGRSKFGEKNILLRQSFTLLELEILKYLALNLGQQISISKIFIELKKRLKTSKDSVYQAIKKLENTYVIYTLKHDEKKLQKIYFKDFGLRNNLCISKDFSHLFENLVLSELFKFKEDFFYNKYFNFYSQISKIAYISSPTLDIDLIKLCAKKILPKALELGIFHVIFITLSSEDSFFEQGVKFEVISFDKFSLGF
>CP012216.1|AXL40088.1|556795_557245_-|DNA-polymerase-III-subunit-beta
MSVTKQLLQMQADAHHLWVKFHNYHWNVKGLQFFSIHEYTEKAYEEMAELFDSCAERVLQLGEKAITCQKVLMENAKSPKVAKDCFTPLEVIELIKQDYEYLLAEFKKLNEAAEKESDTTTAAFAQENIAKYEKSLWMIGATLQGACKM

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	CP012216.1	1360015-1360043	0	1.0
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	CP012216.1	1360014-1360043	0	1.0

1. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to position: 1360015-1360043, mismatch: 0, identity: 1.0

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
caaaaaacttgtattttttatcaaaaaac	Protospacer
*****************************

2. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to position: 1360014-1360043, mismatch: 0, identity: 1.0

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
caaaaaacttgtattttttatcaaaaaact	Protospacer
******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4758-4786	1	0.966
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4779-4807	2	0.931
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4757-4786	2	0.933
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4778-4807	2	0.933
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4800-4828	5	0.828
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	NZ_CP019232	Bacillus thuringiensis strain YGd22-03 plasmid pYGD36, complete sequence	7157-7185	5	0.828
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	MG945564	UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome	4758-4786	5	0.828
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	NZ_CP019232	Bacillus thuringiensis strain YGd22-03 plasmid pYGD36, complete sequence	7156-7185	5	0.833
CP012216_1	1.6|546434|30|CP012216|CRISPRCasFinder	546434-546463	30	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	216495-216524	5	0.833
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	AP018277	Calothrix sp. NIES-4101 plasmid plasmid4 DNA, complete genome	70567-70595	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	MG065650	UNVERIFIED: Campylobacter phage B15, complete genome	45067-45095	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	NC_047776	Escherichia phage ESCO5, complete genome	26221-26249	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	LR597654	Escherichia phage phAPEC8_ev052 genome assembly, chromosome: 1	34072-34100	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	MH160766	Escherichia phage vB_EcoM-Ro121lw, complete genome	26839-26867	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	NC_020079	Escherichia phage phAPEC8, complete genome	31893-31921	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	MN850648	Escherichia phage anhysbys, complete genome	81223-81251	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	LR746137	Escherichia phage vB_EcoM_UP17 genome assembly, chromosome: 1	19713-19741	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	MN850565	Escherichia phage ukendt, complete genome	64332-64360	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	NC_048196	Escherichia phage vB_EcoM_Schickermooser, complete genome	26549-26577	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	NC_047994	Klebsiella phage ZCKP1, complete genome	11010-11038	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	NC_047770	Escherichia phage ESCO13, complete genome	27808-27836	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	MN850571	Escherichia phage nepoznato, complete genome	37910-37938	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	MH051333	Escherichia phage vB_EcoM-Ro121c4YLVW, complete genome	97145-97173	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	MT496970	Escherichia phage Mt1B1_P17, complete genome	123645-123673	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	MN850618	Escherichia phage tuntematon, complete genome	129770-129798	6	0.793
CP012216_1	1.1|546302|29|CP012216|PILER-CR,CRT	546302-546330	29	MN850598	Escherichia phage nieznany, complete genome	28001-28029	6	0.793
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4737-4765	6	0.793
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	MG945564	UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome	4737-4765	6	0.793
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	MN693392	Marine virus AFVG_25M95, complete genome	37724-37752	6	0.793
CP012216_1	1.3|546434|29|CP012216|PILER-CR,CRT	546434-546462	29	NZ_CP031099	Clostridium botulinum strain CFSAN034202 plasmid p2_CFSAN034202, complete sequence	3917-3945	6	0.793
CP012216_1	1.3|546434|29|CP012216|PILER-CR,CRT	546434-546462	29	NZ_CP014146	Clostridium botulinum strain CDC_67190 plasmid pNPD12_1, complete sequence	5604-5632	6	0.793
CP012216_1	1.3|546434|29|CP012216|PILER-CR,CRT	546434-546462	29	NZ_CP025993	Lactobacillus plantarum subsp. plantarum strain LB1-2 plasmid pLB1-2B, complete sequence	33420-33448	6	0.793
CP012216_1	1.3|546434|29|CP012216|PILER-CR,CRT	546434-546462	29	NZ_CP014521	Borrelia anserina Es isolate UTHSCSA plasmid cp5, complete sequence	3482-3510	6	0.793
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	AP018277	Calothrix sp. NIES-4101 plasmid plasmid4 DNA, complete genome	70567-70596	6	0.8
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4799-4828	6	0.8
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	MG945564	UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome	4757-4786	6	0.8
CP012216_1	1.6|546434|30|CP012216|CRISPRCasFinder	546434-546463	30	NZ_CP014521	Borrelia anserina Es isolate UTHSCSA plasmid cp5, complete sequence	3481-3510	6	0.8
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	MN694478	Marine virus AFVG_250M504, complete genome	19978-20008	6	0.806
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	MN694270	Marine virus AFVG_250M505, complete genome	20095-20125	6	0.806
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	MN694656	Marine virus AFVG_250M501, complete genome	19707-19737	6	0.806
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	MN693919	Marine virus AFVG_250M503, complete genome	16185-16215	6	0.806
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	MN694712	Marine virus AFVG_250M502, complete genome	16183-16213	6	0.806
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	NZ_CP015809	Borrelia mayonii strain MN14-1539 plasmid lp54	135-163	7	0.759
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	NZ_CP015795	Borrelia mayonii strain MN14-1420 plasmid lp54, complete sequence	135-163	7	0.759
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	NZ_CP016589	Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence	271669-271697	7	0.759
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	MG592433	Vibrio phage 1.052.A._10N.286.46.C3, partial genome	21822-21850	7	0.759
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	NZ_CP031069	Bacillus sp. JAS24-2 plasmid pl626, complete sequence	484569-484597	7	0.759
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	MK075006	Staphylococcus phage phiSP119-3, complete genome	3951-3979	7	0.759
CP012216_1	1.3|546434|29|CP012216|PILER-CR,CRT	546434-546462	29	MG592587	Vibrio phage 1.216.O._10N.222.55.C12, partial genome	20621-20649	7	0.759
CP012216_1	1.3|546434|29|CP012216|PILER-CR,CRT	546434-546462	29	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	216495-216523	7	0.759
CP012216_1	1.3|546434|29|CP012216|PILER-CR,CRT	546434-546462	29	NC_021277	Fusobacterium nucleatum subsp. animalis 4_8 plasmid unnamed, complete sequence	4914-4942	7	0.759
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	MG065650	UNVERIFIED: Campylobacter phage B15, complete genome	45066-45095	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	MN850571	Escherichia phage nepoznato, complete genome	37910-37939	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	NC_047776	Escherichia phage ESCO5, complete genome	26220-26249	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	LR597654	Escherichia phage phAPEC8_ev052 genome assembly, chromosome: 1	34071-34100	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	MH051333	Escherichia phage vB_EcoM-Ro121c4YLVW, complete genome	97145-97174	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	MH160766	Escherichia phage vB_EcoM-Ro121lw, complete genome	26838-26867	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	MT496970	Escherichia phage Mt1B1_P17, complete genome	123645-123674	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	NC_020079	Escherichia phage phAPEC8, complete genome	31892-31921	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	MN850648	Escherichia phage anhysbys, complete genome	81222-81251	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	LR746137	Escherichia phage vB_EcoM_UP17 genome assembly, chromosome: 1	19712-19741	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	MN850618	Escherichia phage tuntematon, complete genome	129770-129799	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	MN850565	Escherichia phage ukendt, complete genome	64331-64360	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	NC_048196	Escherichia phage vB_EcoM_Schickermooser, complete genome	26548-26577	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	NC_047994	Klebsiella phage ZCKP1, complete genome	11009-11038	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	MN850598	Escherichia phage nieznany, complete genome	28001-28030	7	0.767
CP012216_1	1.4|546302|30|CP012216|CRISPRCasFinder	546302-546331	30	NC_047770	Escherichia phage ESCO13, complete genome	27807-27836	7	0.767
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4736-4765	7	0.767
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	MG945564	UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome	4736-4765	7	0.767
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	MG592433	Vibrio phage 1.052.A._10N.286.46.C3, partial genome	21822-21851	7	0.767
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	NZ_CP031069	Bacillus sp. JAS24-2 plasmid pl626, complete sequence	484568-484597	7	0.767
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	NZ_CP015809	Borrelia mayonii strain MN14-1539 plasmid lp54	135-164	7	0.767
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	NZ_CP015795	Borrelia mayonii strain MN14-1420 plasmid lp54, complete sequence	135-164	7	0.767
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	NZ_CP016589	Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence	271669-271698	7	0.767
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	MK075006	Staphylococcus phage phiSP119-3, complete genome	3951-3980	7	0.767
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	MN693392	Marine virus AFVG_25M95, complete genome	37724-37753	7	0.767
CP012216_1	1.6|546434|30|CP012216|CRISPRCasFinder	546434-546463	30	NC_021277	Fusobacterium nucleatum subsp. animalis 4_8 plasmid unnamed, complete sequence	4913-4942	7	0.767
CP012216_1	1.6|546434|30|CP012216|CRISPRCasFinder	546434-546463	30	NZ_CP025993	Lactobacillus plantarum subsp. plantarum strain LB1-2 plasmid pLB1-2B, complete sequence	33419-33448	7	0.767
CP012216_1	1.6|546434|30|CP012216|CRISPRCasFinder	546434-546463	30	NZ_CP031099	Clostridium botulinum strain CFSAN034202 plasmid p2_CFSAN034202, complete sequence	3917-3946	7	0.767
CP012216_1	1.6|546434|30|CP012216|CRISPRCasFinder	546434-546463	30	NZ_CP014146	Clostridium botulinum strain CDC_67190 plasmid pNPD12_1, complete sequence	5604-5633	7	0.767
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	NZ_CP017773	Paenibacillus crassostreae strain LPB0068 plasmid pPC03, complete sequence	32644-32674	7	0.774
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	NZ_CP040906	Enterococcus faecium strain FB-1 plasmid punnamed, complete sequence	60582-60612	7	0.774
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	NZ_CP040906	Enterococcus faecium strain FB-1 plasmid punnamed, complete sequence	94640-94670	7	0.774
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	MN657144	Pedobacter sp. strain ANT_H27B plasmid pA27BH1, complete sequence	51151-51181	7	0.774
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	NZ_LR135236	Enterococcus faecium isolate E7067 plasmid 2	87344-87374	7	0.774
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	NZ_CP019209	Enterococcus faecium strain 2014-VREF-41 plasmid p41-1, complete sequence	189029-189059	7	0.774
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	NZ_LR135220	Enterococcus faecium isolate E7040 plasmid 2	87693-87723	7	0.774
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	NZ_LR134106	Enterococcus faecium isolate E6043 plasmid 2	87693-87723	7	0.774
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	NZ_CP040873	Enterococcus faecium strain DB-1 plasmid punnamed1	31164-31194	7	0.774
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	NZ_CP040876	Enterococcus faecium strain DB-1 plasmid punnamed2	93188-93218	7	0.774
CP012216_1	1.2|546368|29|CP012216|PILER-CR,CRT	546368-546396	29	KT997865	Uncultured Mediterranean phage uvDeep-CGR2-KM22-C255, complete genome	2164-2192	8	0.724
CP012216_1	1.3|546434|29|CP012216|PILER-CR,CRT	546434-546462	29	MG592583	Vibrio phage 1.213.O._10N.222.54.F10, partial genome	20845-20873	8	0.724
CP012216_1	1.5|546368|30|CP012216|CRISPRCasFinder	546368-546397	30	KT997865	Uncultured Mediterranean phage uvDeep-CGR2-KM22-C255, complete genome	2164-2193	8	0.733
CP012216_1	1.6|546434|30|CP012216|CRISPRCasFinder	546434-546463	30	MG592587	Vibrio phage 1.216.O._10N.222.55.C12, partial genome	20620-20649	8	0.733
CP012216_2	2.1|686057|31|CP012216|CRISPRCasFinder	686057-686087	31	NC_019774	Anabaena cylindrica PCC 7122 plasmid pANACY.04, complete sequence	26535-26565	8	0.742
CP012216_1	1.6|546434|30|CP012216|CRISPRCasFinder	546434-546463	30	MG592583	Vibrio phage 1.213.O._10N.222.54.F10, partial genome	20844-20873	9	0.7

1. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 1, identity: 0.966

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
caaaaaacttggattttttatcaaaaaac	Protospacer
*********** *****************

2. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 2, identity: 0.931

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
caaaaaacatggattttttatcaaaaaac	Protospacer
******** ** *****************

3. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 2, identity: 0.933

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
caaaaaacttggattttttatcaaaaaaca	Protospacer
*********** ***************** 

4. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 2, identity: 0.933

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
caaaaaacatggattttttatcaaaaaact	Protospacer
******** ** ******************

5. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 5, identity: 0.828

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
aaagtgacttggattttttatcaaaaaac	Protospacer
 **. .***** *****************

6. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to NZ_CP019232 (Bacillus thuringiensis strain YGd22-03 plasmid pYGD36, complete sequence) position: , mismatch: 5, identity: 0.828

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
tgaaaaacttgcattttttataaaaaaat	Protospacer
..*********.********* ******.

7. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to MG945564 (UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome) position: , mismatch: 5, identity: 0.828

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
aaagtgacttggattttttatcaaaaaac	Protospacer
 **. .***** *****************

8. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to NZ_CP019232 (Bacillus thuringiensis strain YGd22-03 plasmid pYGD36, complete sequence) position: , mismatch: 5, identity: 0.833

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
tgaaaaacttgcattttttataaaaaaatt	Protospacer
..*********.********* ******.*

9. spacer 1.6|546434|30|CP012216|CRISPRCasFinder matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 5, identity: 0.833

tggagttgaaagagttaataatacc-aatat	CRISPR spacer
atgatttgcaagagttaataatacctaata-	Protospacer
  ** *** **************** **** 

10. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to AP018277 (Calothrix sp. NIES-4101 plasmid plasmid4 DNA, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
gtagaaatgactacagcacaaggttcggc	Protospacer
.******* ************* **  .*

11. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to MG065650 (UNVERIFIED: Campylobacter phage B15, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

12. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to NC_047776 (Escherichia phage ESCO5, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

13. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to LR597654 (Escherichia phage phAPEC8_ev052 genome assembly, chromosome: 1) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

14. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to MH160766 (Escherichia phage vB_EcoM-Ro121lw, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

15. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to NC_020079 (Escherichia phage phAPEC8, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

16. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to MN850648 (Escherichia phage anhysbys, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

17. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to LR746137 (Escherichia phage vB_EcoM_UP17 genome assembly, chromosome: 1) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

18. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to MN850565 (Escherichia phage ukendt, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

19. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to NC_048196 (Escherichia phage vB_EcoM_Schickermooser, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

20. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to NC_047994 (Klebsiella phage ZCKP1, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

21. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to NC_047770 (Escherichia phage ESCO13, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

22. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to MN850571 (Escherichia phage nepoznato, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

23. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to MH051333 (Escherichia phage vB_EcoM-Ro121c4YLVW, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

24. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to MT496970 (Escherichia phage Mt1B1_P17, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

25. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to MN850618 (Escherichia phage tuntematon, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

26. spacer 1.1|546302|29|CP012216|PILER-CR,CRT matches to MN850598 (Escherichia phage nieznany, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

27. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 6, identity: 0.793

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
caaaaaacatggattttttatcaacggcc	Protospacer
******** ** ************ .. *

28. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to MG945564 (UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome) position: , mismatch: 6, identity: 0.793

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
caaaaaacatggattttttatcaacggcc	Protospacer
******** ** ************ .. *

29. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to MN693392 (Marine virus AFVG_25M95, complete genome) position: , mismatch: 6, identity: 0.793

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
caacaaatttgtattttttatcaggatat	Protospacer
*** ***.***************..* *.

30. spacer 1.3|546434|29|CP012216|PILER-CR,CRT matches to NZ_CP031099 (Clostridium botulinum strain CFSAN034202 plasmid p2_CFSAN034202, complete sequence) position: , mismatch: 6, identity: 0.793

tggagttgaaagagttaataataccaata	CRISPR spacer
tggagttgtaagagttaaaaatataaact	Protospacer
******** ********* ****. **. 

31. spacer 1.3|546434|29|CP012216|PILER-CR,CRT matches to NZ_CP014146 (Clostridium botulinum strain CDC_67190 plasmid pNPD12_1, complete sequence) position: , mismatch: 6, identity: 0.793

tggagttgaaagagttaataataccaata	CRISPR spacer
tggagttgtaagagttaaaaatataaact	Protospacer
******** ********* ****. **. 

32. spacer 1.3|546434|29|CP012216|PILER-CR,CRT matches to NZ_CP025993 (Lactobacillus plantarum subsp. plantarum strain LB1-2 plasmid pLB1-2B, complete sequence) position: , mismatch: 6, identity: 0.793

tggagttgaaagagttaataataccaata	CRISPR spacer
tagcagtgaaagtgttaataatagcaata	Protospacer
*.* . ****** ********** *****

33. spacer 1.3|546434|29|CP012216|PILER-CR,CRT matches to NZ_CP014521 (Borrelia anserina Es isolate UTHSCSA plasmid cp5, complete sequence) position: , mismatch: 6, identity: 0.793

--tggagttgaaagagttaataataccaata	CRISPR spacer
cttcggat--aaagagttaacaataccaata	Protospacer
  * *..*  **********.**********

34. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to AP018277 (Calothrix sp. NIES-4101 plasmid plasmid4 DNA, complete genome) position: , mismatch: 6, identity: 0.8

atagaaattactacagcacaagcttataca	CRISPR spacer
gtagaaatgactacagcacaaggttcggca	Protospacer
.******* ************* **  .**

35. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 6, identity: 0.8

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
aaagtgacttggattttttatcaaaaaaca	Protospacer
 **. .***** ***************** 

36. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to MG945564 (UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome) position: , mismatch: 6, identity: 0.8

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
aaagtgacttggattttttatcaaaaaaca	Protospacer
 **. .***** ***************** 

37. spacer 1.6|546434|30|CP012216|CRISPRCasFinder matches to NZ_CP014521 (Borrelia anserina Es isolate UTHSCSA plasmid cp5, complete sequence) position: , mismatch: 6, identity: 0.8

--tggagttgaaagagttaataataccaatat	CRISPR spacer
cttcggat--aaagagttaacaataccaatat	Protospacer
  * *..*  **********.***********

38. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to MN694478 (Marine virus AFVG_250M504, complete genome) position: , mismatch: 6, identity: 0.806

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
cttttcttcttgttttgttttttgcccactt	Protospacer
 * *  **************.***** ****

39. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to MN694270 (Marine virus AFVG_250M505, complete genome) position: , mismatch: 6, identity: 0.806

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
cttttcttcttgttttgttttttgcccactt	Protospacer
 * *  **************.***** ****

40. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to MN694656 (Marine virus AFVG_250M501, complete genome) position: , mismatch: 6, identity: 0.806

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
cttttcttcttgttttgttttttgcccactt	Protospacer
 * *  **************.***** ****

41. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to MN693919 (Marine virus AFVG_250M503, complete genome) position: , mismatch: 6, identity: 0.806

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
cttttcttcttgttttgttttttgcccactt	Protospacer
 * *  **************.***** ****

42. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to MN694712 (Marine virus AFVG_250M502, complete genome) position: , mismatch: 6, identity: 0.806

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
cttttcttcttgttttgttttttgcccactt	Protospacer
 * *  **************.***** ****

43. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to NZ_CP015809 (Borrelia mayonii strain MN14-1539 plasmid lp54) position: , mismatch: 7, identity: 0.759

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
tctcaaacttctattttttattaaaaaat	Protospacer
.   ****** **********.******.

44. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to NZ_CP015795 (Borrelia mayonii strain MN14-1420 plasmid lp54, complete sequence) position: , mismatch: 7, identity: 0.759

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
tctcaaacttctattttttattaaaaaat	Protospacer
.   ****** **********.******.

45. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to NZ_CP016589 (Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence) position: , mismatch: 7, identity: 0.759

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
aatgaaacttgtattttttattaaaagtt	Protospacer
 * .*****************.****. .

46. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to MG592433 (Vibrio phage 1.052.A._10N.286.46.C3, partial genome) position: , mismatch: 7, identity: 0.759

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
tcttgaacttgtattttttatcgaaaacc	Protospacer
.   .*****************.**** *

47. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to NZ_CP031069 (Bacillus sp. JAS24-2 plasmid pl626, complete sequence) position: , mismatch: 7, identity: 0.759

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
aatgaaacttgtattttttattaaaagtt	Protospacer
 * .*****************.****. .

48. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to MK075006 (Staphylococcus phage phiSP119-3, complete genome) position: , mismatch: 7, identity: 0.759

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
aagcaaacttgtcttttttatcaaatgaa	Protospacer
 *. ******** ************ .* 

49. spacer 1.3|546434|29|CP012216|PILER-CR,CRT matches to MG592587 (Vibrio phage 1.216.O._10N.222.55.C12, partial genome) position: , mismatch: 7, identity: 0.759

tggagttgaaagagttaataataccaata	CRISPR spacer
atatgttgaaagagtcaataataccaagt	Protospacer
  . ***********.***********  

50. spacer 1.3|546434|29|CP012216|PILER-CR,CRT matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 7, identity: 0.759

tggagttgaaagagttaataataccaata	CRISPR spacer
atgatttgcaagagttaataatacctaat	Protospacer
  ** *** **************** *  

51. spacer 1.3|546434|29|CP012216|PILER-CR,CRT matches to NC_021277 (Fusobacterium nucleatum subsp. animalis 4_8 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

tggagttgaaagagttaataataccaata	CRISPR spacer
ttttatcaaaaaagttaataataccaata	Protospacer
*   .*..***.*****************

52. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to MG065650 (UNVERIFIED: Campylobacter phage B15, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

53. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to MN850571 (Escherichia phage nepoznato, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

54. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to NC_047776 (Escherichia phage ESCO5, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

55. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to LR597654 (Escherichia phage phAPEC8_ev052 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

56. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to MH051333 (Escherichia phage vB_EcoM-Ro121c4YLVW, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

57. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to MH160766 (Escherichia phage vB_EcoM-Ro121lw, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

58. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to MT496970 (Escherichia phage Mt1B1_P17, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

59. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to NC_020079 (Escherichia phage phAPEC8, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

60. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to MN850648 (Escherichia phage anhysbys, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

61. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to LR746137 (Escherichia phage vB_EcoM_UP17 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

62. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to MN850618 (Escherichia phage tuntematon, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

63. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to MN850565 (Escherichia phage ukendt, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

64. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to NC_048196 (Escherichia phage vB_EcoM_Schickermooser, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

65. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to NC_047994 (Klebsiella phage ZCKP1, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

66. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to MN850598 (Escherichia phage nieznany, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

67. spacer 1.4|546302|30|CP012216|CRISPRCasFinder matches to NC_047770 (Escherichia phage ESCO13, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

68. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
caaaaaacatggattttttatcaacggcca	Protospacer
******** ** ************ .. * 

69. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to MG945564 (UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
caaaaaacatggattttttatcaacggcca	Protospacer
******** ** ************ .. * 

70. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to MG592433 (Vibrio phage 1.052.A._10N.286.46.C3, partial genome) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
tcttgaacttgtattttttatcgaaaacct	Protospacer
.   .*****************.**** **

71. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to NZ_CP031069 (Bacillus sp. JAS24-2 plasmid pl626, complete sequence) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
aatgaaacttgtattttttattaaaagttt	Protospacer
 * .*****************.****. .*

72. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to NZ_CP015809 (Borrelia mayonii strain MN14-1539 plasmid lp54) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
tctcaaacttctattttttattaaaaaatt	Protospacer
.   ****** **********.******.*

73. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to NZ_CP015795 (Borrelia mayonii strain MN14-1420 plasmid lp54, complete sequence) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
tctcaaacttctattttttattaaaaaatt	Protospacer
.   ****** **********.******.*

74. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to NZ_CP016589 (Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
aatgaaacttgtattttttattaaaagttt	Protospacer
 * .*****************.****. .*

75. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to MK075006 (Staphylococcus phage phiSP119-3, complete genome) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
aagcaaacttgtcttttttatcaaatgaat	Protospacer
 *. ******** ************ .* *

76. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to MN693392 (Marine virus AFVG_25M95, complete genome) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
caacaaatttgtattttttatcaggatata	Protospacer
*** ***.***************..* *. 

77. spacer 1.6|546434|30|CP012216|CRISPRCasFinder matches to NC_021277 (Fusobacterium nucleatum subsp. animalis 4_8 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

tggagttgaaagagttaataataccaatat	CRISPR spacer
ttttatcaaaaaagttaataataccaatat	Protospacer
*   .*..***.******************

78. spacer 1.6|546434|30|CP012216|CRISPRCasFinder matches to NZ_CP025993 (Lactobacillus plantarum subsp. plantarum strain LB1-2 plasmid pLB1-2B, complete sequence) position: , mismatch: 7, identity: 0.767

tggagttgaaagagttaataataccaatat	CRISPR spacer
tagcagtgaaagtgttaataatagcaatac	Protospacer
*.* . ****** ********** *****.

79. spacer 1.6|546434|30|CP012216|CRISPRCasFinder matches to NZ_CP031099 (Clostridium botulinum strain CFSAN034202 plasmid p2_CFSAN034202, complete sequence) position: , mismatch: 7, identity: 0.767

tggagttgaaagagttaataataccaatat	CRISPR spacer
tggagttgtaagagttaaaaatataaactc	Protospacer
******** ********* ****. **. .

80. spacer 1.6|546434|30|CP012216|CRISPRCasFinder matches to NZ_CP014146 (Clostridium botulinum strain CDC_67190 plasmid pNPD12_1, complete sequence) position: , mismatch: 7, identity: 0.767

tggagttgaaagagttaataataccaatat	CRISPR spacer
tggagttgtaagagttaaaaatataaactc	Protospacer
******** ********* ****. **. .

81. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to NZ_CP017773 (Paenibacillus crassostreae strain LPB0068 plasmid pPC03, complete sequence) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgc----caactt	CRISPR spacer
ttgtagttcttgttgtgtttgttgcattgca----	Protospacer
 ************* ***** ****    **    

82. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to NZ_CP040906 (Enterococcus faecium strain FB-1 plasmid punnamed, complete sequence) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

83. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to NZ_CP040906 (Enterococcus faecium strain FB-1 plasmid punnamed, complete sequence) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

84. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to MN657144 (Pedobacter sp. strain ANT_H27B plasmid pA27BH1, complete sequence) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtaggtcttgttttgttttttggtagcat	Protospacer
 ***** *************.*** .*.* *

85. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to NZ_LR135236 (Enterococcus faecium isolate E7067 plasmid 2) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

86. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to NZ_CP019209 (Enterococcus faecium strain 2014-VREF-41 plasmid p41-1, complete sequence) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

87. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to NZ_LR135220 (Enterococcus faecium isolate E7040 plasmid 2) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

88. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to NZ_LR134106 (Enterococcus faecium isolate E6043 plasmid 2) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

89. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to NZ_CP040873 (Enterococcus faecium strain DB-1 plasmid punnamed1) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

90. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to NZ_CP040876 (Enterococcus faecium strain DB-1 plasmid punnamed2) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

91. spacer 1.2|546368|29|CP012216|PILER-CR,CRT matches to KT997865 (Uncultured Mediterranean phage uvDeep-CGR2-KM22-C255, complete genome) position: , mismatch: 8, identity: 0.724

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
caaaaaacttatatttttcatcaggtttt	Protospacer
**********.*******.****..   .

92. spacer 1.3|546434|29|CP012216|PILER-CR,CRT matches to MG592583 (Vibrio phage 1.213.O._10N.222.54.F10, partial genome) position: , mismatch: 8, identity: 0.724

tggagttgaaagagttaataataccaata	CRISPR spacer
atatgttgaaagagtcaataatcccaagc	Protospacer
  . ***********.****** ****  

93. spacer 1.5|546368|30|CP012216|CRISPRCasFinder matches to KT997865 (Uncultured Mediterranean phage uvDeep-CGR2-KM22-C255, complete genome) position: , mismatch: 8, identity: 0.733

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
caaaaaacttatatttttcatcaggttttt	Protospacer
**********.*******.****..   .*

94. spacer 1.6|546434|30|CP012216|CRISPRCasFinder matches to MG592587 (Vibrio phage 1.216.O._10N.222.55.C12, partial genome) position: , mismatch: 8, identity: 0.733

tggagttgaaagagttaataataccaatat	CRISPR spacer
atatgttgaaagagtcaataataccaagtg	Protospacer
  . ***********.***********   

95. spacer 2.1|686057|31|CP012216|CRISPRCasFinder matches to NC_019774 (Anabaena cylindrica PCC 7122 plasmid pANACY.04, complete sequence) position: , mismatch: 8, identity: 0.742

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
gttaagctcttgttttgattcttgccatagt	Protospacer
.*  **.********** *********   *

96. spacer 1.6|546434|30|CP012216|CRISPRCasFinder matches to MG592583 (Vibrio phage 1.213.O._10N.222.54.F10, partial genome) position: , mismatch: 9, identity: 0.7

tggagttgaaagagttaataataccaatat	CRISPR spacer
atatgttgaaagagtcaataatcccaagcg	Protospacer
  . ***********.****** ****