CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP030910	Pseudomonas aeruginosa strain Y31 chromosome, complete genome	3 crisprs	csa3,DEDDh,cas3,PD-DExK,WYL,DinG	1	1	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP030910_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030910_1

340729-340842

Orphan

Consensus_repeat	Method
GGCCAAAGAACTGGAGGGCAAGGTATGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP030910_1

>merge|CP030910|1|340729-340842|CRISPRCasFinder
GGCCAAAGAACTGGAGGGCAAGGTATGAGCCAGAACAGCGTATCCCGCTCCGTATCCCGTTCAACAGGCTCTCCATCCAGAAGCGTGGCCAAAGAACTGGAGGGCAAGGTATGA

>CP030910|1|1|340729-340842|CRISPRCasFinder
GGCCAAAGAACTGGAGGGCAAGGTATGA	GCCAGAACAGCGTATCCCGCTCCGTATCCCGTTCAACAGGCTCTCCATCCAGAAGCGT
GGCCAAAGAACTGGAGGGCAAGGTATGA

Protein	Signature genes	Signature genes Name	Protein_function
CP030910.1\|AXL68280.1\|347671_348424_-\|hypothetical-protein	unknown	unknown	unknown
CP030910.1\|AXL68284.1\|350012_350507_+\|Purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|224597
CP030910.1\|AXL68264.1\|328616_329282_-\|Bacterial-regulatory-s,-tetR-family-protein	unknown	unknown	gnl\|CDD\|224228
CP030910.1\|AXL68277.1\|345414_345918_-\|Transcriptional-regulator	unknown	unknown	unknown
CP030910.1\|AXL68283.1\|349809_349899_+\|hypothetical-protein	unknown	unknown	unknown
CP030910.1\|AXL68276.1\|344383_345436_+\|Helix-turn-helix-domain-protein	unknown	unknown	gnl\|CDD\|378890
CP030910.1\|AXL68282.1\|349192_349747_-\|hypothetical-protein	unknown	unknown	unknown
CP030910.1\|AXL68272.1\|338693_339848_+\|Polyamine-ABC-transporter,-ATP-binding-family-protein	unknown	unknown	gnl\|CDD\|183226
CP030910.1\|AXL68269.1\|334533_335904_+\|Aminotransferase	unknown	unknown	gnl\|CDD\|180994
CP030910.1\|AXL68265.1\|329344_330406_-\|Putrescine-binding-periplasmic-protein	unknown	unknown	gnl\|CDD\|270377
CP030910.1\|AXL68266.1\|330661_332038_-\|Glutamine-synthetase,-catalytic-domain-protein	unknown	unknown	gnl\|CDD\|223252
CP030910.1\|AXL68268.1\|333109_334468_+\|Glutamine-synthetase,-catalytic-domain-protein	unknown	unknown	gnl\|CDD\|223252
CP030910.1\|AXL68263.1\|327575_328454_-\|N-carbamoylputrescine-amidase	unknown	unknown	gnl\|CDD\|274553
CP030910.1\|AXL68278.1\|346022_346598_-\|Thiol-disulfide-isomerase	unknown	unknown	gnl\|CDD\|239267
CP030910.1\|AXL68275.1\|341885_344273_-\|Penicillin-acylase-like-protein	unknown	unknown	gnl\|CDD\|225241
CP030910.1\|AXL68271.1\|337541_338639_+\|Putrescine-binding-periplasmic-protein	unknown	unknown	gnl\|CDD\|270377
CP030910.1\|AXL68270.1\|336019_337123_+\|Putrescine-binding-periplasmic-protein	unknown	unknown	gnl\|CDD\|270377
CP030910.1\|AXL68281.1\|348541_349171_+\|Proline-hydroxylase	unknown	unknown	gnl\|CDD\|226274
CP030910.1\|AXL68267.1\|332316_333069_+\|Peptidase-C26-family-protein	unknown	unknown	gnl\|CDD\|336781
CP030910.1\|AXL68279.1\|346710_347652_+\|Alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|225176

Protein	Function_ID	Function_description	E-value
CP030910.1\|AXL68284.1\|350012_350507_+\|Purine-nucleoside-phosphorylase	gnl\|CDD\|224597	COG1683, COG1683, Uncharacterized conserved protein [Function unknown].	2.14015e-67
CP030910.1\|AXL68264.1\|328616_329282_-\|Bacterial-regulatory-s,-tetR-family-protein	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.69613e-08
CP030910.1\|AXL68276.1\|344383_345436_+\|Helix-turn-helix-domain-protein	gnl\|CDD\|378890	pfam12625, Arabinose_bd, Arabinose-binding domain of AraC transcription regulator, N-term. AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].	2.54039e-32
CP030910.1\|AXL68272.1\|338693_339848_+\|Polyamine-ABC-transporter,-ATP-binding-family-protein	gnl\|CDD\|183226	PRK11607, potG, putrescine ABC transporter ATP-binding subunit PotG.	0
CP030910.1\|AXL68269.1\|334533_335904_+\|Aminotransferase	gnl\|CDD\|180994	PRK07480, PRK07480, putative aminotransferase; Validated.	0
CP030910.1\|AXL68265.1\|329344_330406_-\|Putrescine-binding-periplasmic-protein	gnl\|CDD\|270377	cd13659, PBP2_PotF, The periplasmic substrate-binding component of an ABC putrescine transport system and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic substrate-binding domain that serves as the primary polyamine receptor of ABC-type putrescine-preferential transporter from gram-negative bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	8.00795e-165
CP030910.1\|AXL68266.1\|330661_332038_-\|Glutamine-synthetase,-catalytic-domain-protein	gnl\|CDD\|223252	COG0174, GlnA, Glutamine synthetase [Amino acid transport and metabolism].	1.09186e-161
CP030910.1\|AXL68268.1\|333109_334468_+\|Glutamine-synthetase,-catalytic-domain-protein	gnl\|CDD\|223252	COG0174, GlnA, Glutamine synthetase [Amino acid transport and metabolism].	5.71424e-158
CP030910.1\|AXL68263.1\|327575_328454_-\|N-carbamoylputrescine-amidase	gnl\|CDD\|274553	TIGR03381, putative_carbon-nitrogen_hydrolase, N-carbamoylputrescine amidase. Members of this family are N-carbamoylputrescine amidase (3.5.1.53). Bacterial genes are designated AguB. The AguAB pathway replaces SpeB for conversion of agmatine to putrescine in two steps rather than one. [Central intermediary metabolism, Polyamine biosynthesis].	0
CP030910.1\|AXL68278.1\|346022_346598_-\|Thiol-disulfide-isomerase	gnl\|CDD\|239267	cd02969, PRX_like1, Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic cysteine found in PRXs, which aligns to the second cysteine in the CXXC motif of TRX. In addition, these proteins do not contain the other two conserved residues of the catalytic triad of PRX. PRXs confer a protective antioxidant role in cells through their peroxidase activity in which hydrogen peroxide, peroxynitrate, and organic hydroperoxides are reduced and detoxified using reducing equivalents derived from either thioredoxin, glutathione, trypanothione and AhpF.	0.00282108
CP030910.1\|AXL68275.1\|341885_344273_-\|Penicillin-acylase-like-protein	gnl\|CDD\|225241	COG2366, COG2366, Protein related to penicillin acylase [General function prediction only].	0
CP030910.1\|AXL68271.1\|337541_338639_+\|Putrescine-binding-periplasmic-protein	gnl\|CDD\|270377	cd13659, PBP2_PotF, The periplasmic substrate-binding component of an ABC putrescine transport system and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic substrate-binding domain that serves as the primary polyamine receptor of ABC-type putrescine-preferential transporter from gram-negative bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	0
CP030910.1\|AXL68270.1\|336019_337123_+\|Putrescine-binding-periplasmic-protein	gnl\|CDD\|270377	cd13659, PBP2_PotF, The periplasmic substrate-binding component of an ABC putrescine transport system and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic substrate-binding domain that serves as the primary polyamine receptor of ABC-type putrescine-preferential transporter from gram-negative bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	0
CP030910.1\|AXL68281.1\|348541_349171_+\|Proline-hydroxylase	gnl\|CDD\|226274	COG3751, EGL-9, Predicted proline hydroxylase [Posttranslational modification, protein turnover, chaperones].	3.27136e-68
CP030910.1\|AXL68267.1\|332316_333069_+\|Peptidase-C26-family-protein	gnl\|CDD\|336781	pfam07722, Peptidase_C26, Peptidase C26. These peptidases have gamma-glutamyl hydrolase activity; that is they catalyze the cleavage of the gamma-glutamyl bond in poly-gamma-glutamyl substrates. They are structurally related to pfam00117, but contain extensions in four loops and at the C-terminus.	1.81471e-108
CP030910.1\|AXL68279.1\|346710_347652_+\|Alpha/beta-hydrolase	gnl\|CDD\|225176	COG2267, PldB, Lysophospholipase [Lipid metabolism].	6.84301e-56

>CP030910.1|AXL68272.1|338693_339848_+|Polyamine-ABC-transporter,-ATP-binding-family-protein
MAIASGAYKKALEGNQQPKEVLVKIDRVTKQFDETLAVDTVSLTINKGEIFALLGGSGSGKSTLLRMLAGFERPTEGRIFLDGQDITDLPPYERPINMMFQSYALFPHMSVAQNIAFGLKQDGLPKAEIDERVAEMLKLVHMTQYAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRSQMQLELVEIIERVGVTCVMVTHDQEEAMTMAQRIAIMHLGCIEQIGSPMDIYETPASRLVCEFIGNVNLFDGVLVEDVQDHAVIACPQLENPIYIGHGISTRAEDKRITYALRPEKVMISAQKPDNLEHAGHNWAQGTVYDIAYLGGHSVYYIKLASGMIVQAFMANAERHVARPTWDQSVYISWYDDSGVVLQS
>CP030910.1|AXL68271.1|337541_338639_+|Putrescine-binding-periplasmic-protein
MQHSIGKTLLVAALATAIAGPVQAEKKSLHIYNWTDYIAPTTLKDFTKESGIDVSYDVFDSNETLEGKLVSGHSGYDIVVPSNNFLGKQIQAGAFQKLDKSKLPNWKNLDPALLKQLEVSDPGNQYAVPYLWGTNGIGYNVAKVKEVLGDQPIDSWAILFEPENMKKLAKCGVAFMDSGDEMLPAALNYLGLDPNTHDPKDYKKAEEVLTKVRPYVSYFHSSKYISDLANGNICVAFGYSGDVFQAAARAEEAGKGIDIQYVIPKEGANLWFDLMAIPADAKAADNAYAFIDYLLRPEVIAKVSDYVGYANAIPGARPLMDKSVSDSEEVYPPQAVLDKLYVSAVLPAKVLRLQTRTWTRIKTGK
>CP030910.1|AXL68270.1|336019_337123_+|Putrescine-binding-periplasmic-protein
MMKRFGKTLLALTLAGSVAGMAQAADNKVLHVYNWSDYIAPDTLEKFTKETGIKVVYDVYDSNEVLEAKLLAGKSGYDVVVPSNSFLAKQIKAGVYQKLDKSKLPNWKNLNKDLMHTLEVSDPGNEHAIPYMWGTIGIGYNPDKVKAAFGDNAPVDSWDLVFKPENIQKLKQCGVSFLDSPTEILPAALHYLGYKPDTDNPKELKAAEELFLKIRPYVTYFHSSKYISDLANGNICVAIGYSGDIYQAKSRAEEAKNKVTVKYNIPKEGAGSFFDMVAIPKDAENTEGALAFVNFLMKPEIMAEITDVVQFPNGNAAATPLVSEAIRNDPGIYPSEEVMKKLYTFPDLPAKTQRAMTRSWTKIKSGK
>CP030910.1|AXL68269.1|334533_335904_+|Aminotransferase
MNSQITNAKTREWQALSRDHHLPPFTDYKQLNEKGARIITKAEGVYIWDSEGNKILDAMAGLWCVNVGYGREELVQAATRQMRELPFYNLFFQTAHPPVVELAKAIADVAPEGMNHVFFTGSGSEANDTVLRMVRHYWATKGQPQKKVVIGRWNGYHGSTVAGVSLGGMKALHEQGDFPIPGIVHIAQPYWYGEGGDMSPDEFGVWAAEQLEKKILEVGEENVAAFIAEPIQGAGGVIVPPDTYWPKIREILAKYDILFIADEVICGFGRTGEWFGSQYYGNAPDLMPIAKGLTSGYIPMGGVVVRDEIVEVLNQGGEFYHGFTYSGHPVAAAVALENIRILREEKIIEKVKAETAPYLQKRWQELADHPLVGEARGVGMVAALELVKNKKTRERFTDKGVGMLCREHCFRNGLIMRAVGDTMIISPPLVIDPSQIDELITLARKCLDQTAAAVLA
>CP030910.1|AXL68268.1|333109_334468_+|Glutamine-synthetase,-catalytic-domain-protein
MTTKLDQLTSWLKERKITEVECLISDLTGIARGKISPTNKFIAEKGMRLPESVLLQTVTGDYVEDDIYYDLLDPADIDMVCRPDENAVFLVPWAIEPTAMVIHDTFDKLGNPIELSPRNILKRVLKMYADKGWRPIVAPEMEFYLTKRSDDPDYPLQAPVGRSGRQETGRQSFSIDAANEFDPLFEDMYDWCEAQGLDLDTLIHEEGTAQMEINFRHGDALDLADQILVFKRTMREAALKHNVAATFMAKPMTGEPGSAMHLHQSIVDVKTGKNIFSNADGTMSELFLHHIGGLQKFIPEVLPLFAPNVNSFRRFLPDTSAPVNVEWGEENRTVGLRVPDSSPENRRVENRLAGADANPYLALAASLLCGYIGMVEGIKPSAQVKGRGYERRNLRLPLTIEAALERMENCKPLEQYLGSKFISGYVAVKRAEHENFKRVISSWEREFLLLSV
>CP030910.1|AXL68267.1|332316_333069_+|Peptidase-C26-family-protein
MSRLPLIGVTACTKQIGLHPYHIAGDKYLRAVVNGAGGLPLIIPALGESIDQAALLDSVDGLLFTGSPSNVEPRHYSGPASEPGTLHDSDRDATTLPLVRAAIDAGIPVLGICRGFQEMNVAFGGSLHQKVHEVGTFMDHREPADQPLEVQYAPRHAMHVQPGGVLAGIGLPSEFQVNSIHGQGVDRLAPGLRVEALAPDGLVEAISVEGAKAFALGVQWHPEWQVLTNPNYLAIFQAFGKACSKRAGQR
>CP030910.1|AXL68266.1|330661_332038_-|Glutamine-synthetase,-catalytic-domain-protein
MSVPQRAVQLTEPSEFLKEHPEVQFVDLLIADMNGVVRGKRIERNSLNKVFEKGINLPASLFALDITGSTVESTGLGLDIGDADRICYPIPGTLSMEPWQKRPTAQLLMTMHELEGEPFFADPREVLRQVVARFTEMELTIVAAFELEFYLIDQENVNGRPQPPRSPISGKRPQSVQVYSIDDLDEYVECLQDIIDGARAQGIPADAIVAESAPAQFEVNLNHVNDALKACDHAVLLKRLVKNIAYDHEMDTTFMAKPYPGQAGNGLHVHISLLDKHGNNIFTSEDPEQNAALRHAIGGVLETLPASMAFLCPNVNSYRRFGSQFYVPNAPSWGLDNRTVALRVPTGSPDAVRLEHRVAGADANPYLLLAAVLAGVHHGLTNKVEPGAPIEGNSYEQMEPSLPNNLRDALRELDESEIMAKYIDPKYIDIFVACKESELEEFEHSISDLEYNWYLHTV
>CP030910.1|AXL68265.1|329344_330406_-|Putrescine-binding-periplasmic-protein
MPRLSALLFLALAPWLAQAEETLRVYNWNDYIDPQVLESFQKDTGIRVEYHTFATAEELDKALRSGEAIDVAVPSHDTLPALLKDNLLRPLDFTQLPNRSHLDRQLLSKLAAVDPDNRHAVPYLWGAVGLAINTPQAEAAYGGPLPNSWSLLFDASQSQRLKSCGISLLDAPDETLAILLNYQGRNLGRTAPSQVRRAAEALHGLRPNLRYVDSERYIADLEGGRLCLAMAWVGDALRAAKAGQPVSFEVPQEGSVLFIDNLVIPAGAQHPREAHRFIDYLMQPKIAAQITAATLYPSGNADAAGFLDPALRQQPGLYPDRDTSRRLFALETPPEKLRPVVDEIWKAFRGASH
>CP030910.1|AXL68264.1|328616_329282_-|Bacterial-regulatory-s,-tetR-family-protein
MQPTSPTRKPRASSQARIAAILDAARGLLADEGIGGLSIYSVAERAEMPPSSVYHFFPSVPALLQGLTGEVHAAFRACLEQPVDHAGLRCWRDLSRIVEERMLAVYARDAAARQLILASHGLAEVTQADRQHDVQLGQAMRALFERHFLLPPLPTDIEIFSLAMELGDRVYALSVQRHGIIDARLAEEGMRVFDAYLGLYLPPILEKRSEPLAGFISDLNR
>CP030910.1|AXL68263.1|327575_328454_-|N-carbamoylputrescine-amidase
MTRNVTVAATQMACSWDRPANIARAEKLVRQAAARGAQIILIQELFETPYFCQKPNPDYLQLATTVEENAAIAHFQALARELQVVLPISFFERAGRARFNSIAVIDADGGNLGVYRKSHIPDGPGYHEKYYFNPGDTGFKVWQTRYARIGVGICWDQWFPESARSMALLGAELLFYPTAIGSEPHDASISSRDHWQRVQQGHAGANLMPLVASNRIGREEQDGYDITFYGSSFIADPFGEKVEELNRTEEGILVHTFDLDALERTRSAWGVFRDRRPNLYGPLKTLDGSLES
>CP030910.1|AXL68275.1|341885_344273_-|Penicillin-acylase-like-protein
MKRTLTVIAVAVAAAAAGGAWYLHAKQPLRNGSLAVAHLQAPVDVRYDERGVPHLYAQNQTDLYRALGYVHAQDRLFQMEMLRRLARGELAEVLGPKLVDTDRLFRTLRIRDHAAEYSARQDKQSQPWKVLEAYLDGVNQFQENNPAPLEFDLLGIPRRPFTPEDTLSIAGYMAYSFAAAFRTEPVLTYIRDELGSDYLRIFDLDWHPQGVLTPSGALGAGDWKDLGALARLSQQALEDAGLPQFEGSNAWVVAGSRTASGKPLLAGDPHIRFAAPAVWYEAQLSAPGFELYGHHQALNPFASLGHNRAFGWSLTMFQNDDLDLVAEKVNPDNPNQVWYQGEWVDLQSEEQEIAVKGAAPVKLTLRRSPHGPIVNDALGASSGKTPIAMWWAFLETENPVLDAFYQLNRADTLAKARAAASKIHSPGLNLVWANAAGDIGWWASAALPKRPEGVNPSFILDGSKGEADKSGFYPFADNPQEENPARGYIVSANFQPVPANGRPIPGYYNLADRGQWLDTQLADRGTKWNLDNSRALQLGNRTGYAPRLLAPLLPVLREVVDDAEGKRLVEQLAAWKGDYPVDSTAATLFNQLLFQIAEGALHDELGDAFFDSLIATRAIDSALPRLAGDADSPWWDDRRTEHRETRADIVRTAWNASLAHLRSTLGNDPSGWLWGKAHTLTHEHALGQQALLKRLLNVGPFAAPGTHEVPNNLSAKIGPAPWAVTYGPSTRRLVDFADPTHSLGINPVGQSGVPFDGHYDDQAEAYIEGHYLPQHYEENEVKANSKGVLVLEPKR
>CP030910.1|AXL68276.1|344383_345436_+|Helix-turn-helix-domain-protein
MQDDPSTSPLTHSATLRRLLYEALDALGLDPTRVYRSVYRRIPLPPPTLGGRLVHDNAPLFWTELAAVTGDADIGLHLGEAMKPRLLDVVGYLLLSARDLEEALRSFVRFQHILSGGFAARLEVEGETARLILDINYLGYASLRQQIECLMLLFLKLLALISDDEFVAERIEFRHRAPPRLGEHRRLFGRLPLFSRPHDALVFSAALLRRPSRNANPDMHDVLTRHAEEQSRELSENRLLNRVRYLIELRLGEGYGLRQCAAELGLGSGALQRALAAGGASFRQVRDEVRRQRASEMLLAGRAIREVAKACGFAELSPFYRAFRRWHAAPPEQYRARLAKREEGYSTSGT
>CP030910.1|AXL68277.1|345414_345918_-|Transcriptional-regulator
MSLRPTLALLALVSLPLMAAQNDPQPSSKELMKEHQAQIQNDLADVDYKRKRIVEANMNLTDQEGEKFWPIYNTYRTESDKLSKETLKLLLDYAQAYNSGNVSDDQASKLIERVDDLQEDRLELRDKYVKRIAKNVSPKRAMRFLQIEIQLDAIATLEIGRQVPLVE
>CP030910.1|AXL68278.1|346022_346598_-|Thiol-disulfide-isomerase
MTPRRKTLLVSLVGLLWAGGLLAAYWWFEIRYIRPFSEQTTLFSGDSLRLPAELAGPGAIRLVHFWDPACPCNVGNQQHLGELIERFAGKGVEFHVLQKPGSQGRLPDNLAALRPLAGLPGSEQLPASPAVAIWDRDGRLAYFGPYSEGAVCTSSNSFIEPILEALLQGRPVDATHTLAVGCYCPWTPEKG
>CP030910.1|AXL68279.1|346710_347652_+|Alpha/beta-hydrolase
MSEAFNPDYLRQHLRPLAAAEADAAVLAYQAYYGLDLRSRHPRLQARLGSMAVDGRRLAVQAWLLPEARGSLLLMHGYYDHMGLYRHVVDWALGMGFSVLACDLPGHGLSEGERASIRDFAEYQAVFKGLLGQAAELDLAAPWHLCGQSTGGAILLDYLLHGGERPELGETILLAPLVRPRAWGWSKLSYRLLSPFVDSIPRRFSENSSDPQFLDFLREHDPLQPRTLPTAWVGALTRWVPRIERAPRRALSPLVVQGESDETVDWRHGLKVLREKFDEPRILLLEEARHHLANESEGLRRRYFDFLSDALGA
>CP030910.1|AXL68280.1|347671_348424_-|hypothetical-protein
MRALLAFALLLVGLPALADPYQRLYQAAGWPDQRAHFSDALDAAQKRYQDKLPPALYQTLVDNSNRRFAPAEVDQRALNGLRENLPDSASPLNFFESPLGRKVVAAEVLATRRDQLLQHSNGLPRQTASEPRRALVKRLAQVLPAREAGAEVSLALAGVAADSLSQMLPGLPGLLGGGQTGQLLEGQRQRLVQQIGADLENTLLYVYRDLSDAELTQYVNFAESPAGRSYYQAALAALKAGLAVDQAVAP
>CP030910.1|AXL68281.1|348541_349171_+|Proline-hydroxylase
MHINVNHPLLHRIVDELVDQGWSHQSIFMPERLTTRLAEECRTRAVAGDLTPAAIGRGDGQVIREGIRGDLTQWLEPGESEACDEYLGVMDSLRQALNASLFLGLEDFECHFALYPPGAYYQKHVDRFRDDDARTVSAVLYLNDAWLPEHGGALRLHLPQRQVDIQPTGGSLVVFMSAGTEHEVLPASRDRLSLTGWFRRRNESLLQLS
>CP030910.1|AXL68282.1|349192_349747_-|hypothetical-protein
MLPTRSLLPFFLAPALLASAASQAAMEALDNDSLSQVTGQAGISLRLDLRAGAARVAWVDDGGSLSLRNLVIDNGCVKAGDCPDGRGGNIPLGAAQLGLSLPIFGVEQPTLALDVTTGSGGGQQLAISLPDLATINDQLIASGLPAQRIRLRVASDLYIGDNSIGRIELRDITDLRGTIKVWGH
>CP030910.1|AXL68283.1|349809_349899_+|hypothetical-protein
MGRPQFYPKDRQEIALVPAIRALERYREA
>CP030910.1|AXL68284.1|350012_350507_+|Purine-nucleoside-phosphorylase
MQKVLVSRCLLGHLVRYDGGSHGPFDLLSRWHAQGRIVALCPEVAGGLPTPRPPAEIPGGQGGEVLDRLNRVFTVDGEDVSEAFLLGAEAAVELVRRHDIRMAVLKARSPSCGNLENYDGRFNGNRVAGEGVTAAALKRMGVLVFNEDELDRAAVCLAGLDAGG

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Crispr_ID: CP030910_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030910_2

2734301-2734402

Orphan

Consensus_repeat	Method
GCGGCGGGTATCGGCGGATAACGCC	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of CP030910_2

>merge|CP030910|2|2734301-2734402|CRISPRCasFinder
GCGGCGGGTATCGGCGGATAACGCCTCCGGCGTTATTCGCCCTACGCGGAGGGTTCCCAGCTTTCGCTCCGCCGTTGCGGCGGGGTATCGGCGGATAACGCC

>CP030910|2|2|2734301-2734402|CRISPRCasFinder
GCGGCGGGTATCGGCGGATAACGCC	TCCGGCGTTATTCGCCCTACGCGGAGGGTTCCCAGCTTTCGCTCCGCCGTTG
CGGCGGGGTATCGGCGGATAACGCC

Protein	Signature genes	Signature genes Name	Protein_function
CP030910.1\|AXL70478.1\|2739516_2740446_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
CP030910.1\|AXL70476.1\|2738137_2738701_-\|Peptidyl-prolyl-cis-trans-isomerase-A	unknown	unknown	gnl\|CDD\|182824
CP030910.1\|AXL70474.1\|2735694_2735961_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371321
CP030910.1\|AXL70482.1\|2742764_2743100_-\|Export-related-chaperone-CsaA-family-protein	unknown	unknown	gnl\|CDD\|182232
CP030910.1\|AXL70477.1\|2738682_2739510_-\|Beta-ketoadipate-enol-lactone-hydrolase	unknown	unknown	gnl\|CDD\|131480
CP030910.1\|AXL70465.1\|2726426_2727788_-\|serine/threonine-protein-kinase	unknown	unknown	unknown
CP030910.1\|AXL70473.1\|2734537_2735662_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225688
CP030910.1\|AXL70467.1\|2728445_2729303_+\|Glycine-betaine-binding-protein	unknown	unknown	gnl\|CDD\|270357
CP030910.1\|AXL70463.1\|2724622_2725480_-\|Quercetin-2,3-dioxygenase	unknown	unknown	gnl\|CDD\|224655
CP030910.1\|AXL70472.1\|2734104_2734263_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378708
CP030910.1\|AXL70464.1\|2725619_2726423_-\|ABC-transporter	unknown	unknown	gnl\|CDD\|225409
CP030910.1\|AXL70469.1\|2729828_2731484_+\|Acetate-permease-ActP-(Cation/acetate-symporter)	unknown	unknown	gnl\|CDD\|236495
CP030910.1\|AXL70468.1\|2729520_2729832_+\|Inner-membrane-protein-yjcH	unknown	unknown	gnl\|CDD\|225704
CP030910.1\|AXL70479.1\|2740645_2740963_+\|3-phosphoglycerate-kinase	unknown	unknown	unknown
CP030910.1\|AXL70475.1\|2736242_2738075_-\|ABC-transporter-ATP-binding-protein/permease	unknown	unknown	gnl\|CDD\|224055
CP030910.1\|AXL70480.1\|2741109_2741751_+\|FMN-dependent-NADH-azoreductase-3	unknown	unknown	gnl\|CDD\|224103
CP030910.1\|AXL70470.1\|2731573_2733373_+\|histidine-kinase	unknown	unknown	gnl\|CDD\|225457
CP030910.1\|AXL70466.1\|2727930_2728152_-\|membrane-protein	unknown	unknown	gnl\|CDD\|225746
CP030910.1\|AXL70481.1\|2741876_2742755_-\|Permease	unknown	unknown	gnl\|CDD\|307170
CP030910.1\|AXL70471.1\|2733369_2733996_+\|Exonuclease-family-protein	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|236391

Protein	Function_ID	Function_description	E-value
CP030910.1\|AXL70478.1\|2739516_2740446_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.24343e-39
CP030910.1\|AXL70476.1\|2738137_2738701_-\|Peptidyl-prolyl-cis-trans-isomerase-A	gnl\|CDD\|182824	PRK10903, PRK10903, peptidylprolyl isomerase A.	5.29669e-93
CP030910.1\|AXL70474.1\|2735694_2735961_-\|hypothetical-protein	gnl\|CDD\|371321	pfam10976, DUF2790, Protein of unknown function (DUF2790). This family of proteins with unknown function appear to be restricted to Pseudomonadaceae.	1.53651e-35
CP030910.1\|AXL70482.1\|2742764_2743100_-\|Export-related-chaperone-CsaA-family-protein	gnl\|CDD\|182232	PRK10089, PRK10089, chaperone CsaA.	1.70058e-64
CP030910.1\|AXL70477.1\|2738682_2739510_-\|Beta-ketoadipate-enol-lactone-hydrolase	gnl\|CDD\|131480	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase. Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other].	2.13956e-42
CP030910.1\|AXL70466.1\|2727930_2728152_-\|membrane-protein	gnl\|CDD\|225746	COG3205, COG3205, Predicted membrane protein [Function unknown].	8.76037e-33
CP030910.1\|AXL70473.1\|2734537_2735662_+\|hypothetical-protein	gnl\|CDD\|225688	COG3146, COG3146, Uncharacterized protein conserved in bacteria [Function unknown].	0
CP030910.1\|AXL70467.1\|2728445_2729303_+\|Glycine-betaine-binding-protein	gnl\|CDD\|270357	cd13639, PBP2_OpuAC_like, Substrate binding domain of Lactococcus lactis ABC-type transporter OpuA and related proteins; the type 2 periplasmic binding protein fold. This subfamily is part of a high affinity multicomponent binding-protein-dependent transport system specific to betaine compounds for osmoregulation. The periplasmic substrate-binding domain, which is often fused to the permease component of the ATP-binding cassette transporter complex, is involved in uptake of osmoprotectants (also termed compatible solutes) such as glycine betaine and proline betaine. Many microorganisms accumulate these compatible solutes in response to high osmolarity to offset the loss of cell water. This domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.55277e-117
CP030910.1\|AXL70463.1\|2724622_2725480_-\|Quercetin-2,3-dioxygenase	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	1.4231e-96
CP030910.1\|AXL70464.1\|2725619_2726423_-\|ABC-transporter	gnl\|CDD\|225409	COG2853, VacJ, Surface lipoprotein [Cell envelope biogenesis, outer membrane].	6.05055e-101
CP030910.1\|AXL70469.1\|2729828_2731484_+\|Acetate-permease-ActP-(Cation/acetate-symporter)	gnl\|CDD\|236495	PRK09395, actP, cation/acetate symporter ActP.	0
CP030910.1\|AXL70468.1\|2729520_2729832_+\|Inner-membrane-protein-yjcH	gnl\|CDD\|225704	COG3162, COG3162, Predicted membrane protein [Function unknown].	2.28294e-48
CP030910.1\|AXL70475.1\|2736242_2738075_-\|ABC-transporter-ATP-binding-protein/permease	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.066e-156
CP030910.1\|AXL70480.1\|2741109_2741751_+\|FMN-dependent-NADH-azoreductase-3	gnl\|CDD\|224103	COG1182, AcpD, Acyl carrier protein phosphodiesterase [Lipid metabolism].	1.18979e-103
CP030910.1\|AXL70470.1\|2731573_2733373_+\|histidine-kinase	gnl\|CDD\|225457	COG2905, COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains [Signal transduction mechanisms].	0
CP030910.1\|AXL70472.1\|2734104_2734263_+\|hypothetical-protein	gnl\|CDD\|378708	pfam11752, DUF3309, Protein of unknown function (DUF3309). This family is conserved in bacteria but its function is not known.	2.8739e-06
CP030910.1\|AXL70481.1\|2741876_2742755_-\|Permease	gnl\|CDD\|307170	pfam00892, EamA, EamA-like transporter family. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.	7.20687e-12
CP030910.1\|AXL70471.1\|2733369_2733996_+\|Exonuclease-family-protein	gnl\|CDD\|236391	PRK09145, PRK09145, 3'-5' exonuclease.	2.00701e-94

>CP030910.1|AXL70472.1|2734104_2734263_+|hypothetical-protein
MSLGTILLIILILLLIGGLPVFPHSRNWGYGPSGIIGALLVVLLVLLLLGMI
>CP030910.1|AXL70471.1|2733369_2733996_+|Exonuclease-family-protein
MNTMVKLPDSRWPGWRRRLYWWMHEAVEAEEVISLDLETTSLDPRRADILSIGAVLVRRGKLVMGERLELYVEPPPSLDAESIRIHKLRRADLEGQLQLEQALRQVLAFIGDRPLLGYYLSFDVAVLNRHLRQLLDRQLHNPSIEISSLYHRKVSRHFPDAHIDLRFDTLARALDVPVSGRHTALGDAQAVALMFMRLLKGPAPKVIH
>CP030910.1|AXL70470.1|2731573_2733373_+|histidine-kinase
MPDSFNFASPPFDQLRPHQRETLKQALSVGYYAPGETLLEAGSAVPGLFVLLKGVVEERGDDGRVFAQYAADDLFDVRGLFSGSSKHRYLAIEESIVYELPASCFHQLCGENPGFARFFQADLAAKRQLAQRDGQNLAEFILTRIAREHLLPALEVEASLSLGDAARLQLSHGADALLVRLERDGPELGIVTRTDLMSAHFRDGRSELEAIGPLAHGPLASVELGDFLFDAMILMTRQRIERVAVTEDGQVIGLLHLTQVLSLFSTHSHVLALRIARADDLGDLRRCAETLDTLIATLAGNGIRLRFIMQLVSALNEQLLERLFELLLPPTLRGRCCLLVMGSEGRGEQLLKTDQDNALVLADDLPQEQALAMMQRFSAALLEFGYPPCPGGVMASRPEWCKPLAAWQAELRGTLLEGKPEQLLRLSILADAWPVAGNLQLFEPLRRQLRGFADGGERWLADIAAAALQFDTPLTFLGQLKTQDARLDLKRGGIFPIVHGIRTLALREGLETRGTLARIEALKRHKVLEARLADDLSESFELFLQLRLTRQLAGQRDGRQQGLDVSGMSRHDRDMLRYGLHVVKKFKQSVARQFHLETR
>CP030910.1|AXL70469.1|2729828_2731484_+|Acetate-permease-ActP-(Cation/acetate-symporter)
MIARLLAALGLAAFAPALWADALTGDVQRQPLNVSAIVMFVAFVGATLCITYWASKRNRSAADYYAAGGRITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSIGFLVGWPIILFLIAERLRNLGKYTFADVASYRLKQKQIRTLSACGSLVVVAFYLIAQMVGAGKLIELLFGLNYHVAVVLVGILMVLYVLFGGMLATTWVQIIKAVLLLSGASFMAIMVLKHVNFDVSTLFSEAIKVHPKGEAIMSPGGLVKDPISAFSLGFALMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGAILLVSTNPDFKDATGALIGGNNMAAVHLADAVGGSLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVFKGGKANEKDELRVSKMTTVALGVVAIVLGILFEKQNIAFMVGLAFSIAASCNFPVLLLSMYWKKLTTRGAMIGGWMGLITAVGLMVLGPTIWVQILGHEKAIYPYEYPALFSMIVAFVGIWFFSITDKSAAADEERARFFPQFIRSQTGLGASGAVAH
>CP030910.1|AXL70468.1|2729520_2729832_+|Inner-membrane-protein-yjcH
MNDSIYQRIDTNPRFKELVAKRERFAWILSSIMLGLYVIFILLIAFQPQLLGARISPDSSVTWGIPMGVGLILAAFILTGLYVRRANGEFDSLNQEILKEAQQ
>CP030910.1|AXL70467.1|2728445_2729303_+|Glycine-betaine-binding-protein
MRMMRRLLCWSAGLAMSAAVGMAAAADKPVITIGYVDGWSDSVATTHVAAEVIREKLGYEVKLMPVAAGIMWQGVARGKLDAMLSAWLPGTHGAYYEKMKDKVVNLAINYPDARIGLIVPEYVSANSIADLQAQKDAFGGRVVGIDAGAGVMIKTDEAIKQYGLDYKLVASSGSGMIAELTRAENEKKPVVVTGWIPHWMFAKWKLKFLDDPKKVYGDTEHVDTVANPALEAKAKPVWEFLKKFGWRDGNEVGQVMLAIQEGAKPEDAAKQWVAANPGRVKDWVQ
>CP030910.1|AXL70466.1|2727930_2728152_-|membrane-protein
MLKTLTFTVMHFIIAFSVAYALTGSIAVGGLVAAVEPLCNSVGFYFHEKIWKRFEKDGAPRPASAHGWLHRHA
>CP030910.1|AXL70465.1|2726426_2727788_-|serine/threonine-protein-kinase
MPHFLRFAALLGGLALGCANLAQARDVDAASYGYPLTNPFEATIATTPPELRPELPHSEDIDQKDYSLKLRPEREFALPDNFWPVKKLRYRLARQDHAAPLIFIIAGTGAHYASSFPEYLKKLFYQAGYHVVQLSSPTSWDFMASASRFATPGFSSDDADDLYRVMQAVRAQQRDLPVTDYYLTGYSLGALNAAFVSHLDESRRSFNFKKVLLLNPPVNLYTSVSNLDKLVETQVKGITDSRTFYEVVLSKLTRYFRQKGYVDINDAMLYDFQQSKQRLSNEEMAMLIGTSFRFSAADIAFTSDLVNRRGLITPPNYPINEGTSLEPFFKRALQCDFECYMTEQLIPMWRARYDGGSLTQLVNQVSLYKLQDYLHDSPKIAVMHNADDVILGPGDLGFLRRTFGERLTVYPYGGHCGNLNYKVNAQDMLDFFATPAAGQTQVASAALTQQAGN
>CP030910.1|AXL70464.1|2725619_2726423_-|ABC-transporter
MSRTAHWMFALLLSAAASAQADEAAAPAELPPRQLDGDGFSRPLDQLKFNPGLDQREFERATLDALNMYDPWESWNRRVYHFNYRFDEWVFLPVVRGYEYVTPHFVRSGVSNFFDNLGDVPNLLNNLAQLKGKAAMETTARLLFNTTFGVLGLWDPATRMGLHKRSEDFGQTLGFYGVGSGPYLVLPILGPSNLRDTGGLVVDYVGEYQVNYLNVPQASGDHPEITALRVVDKRYNTSFRYGQMNSPFEYEKLRYIYTEARKLQIAE
>CP030910.1|AXL70463.1|2724622_2725480_-|Quercetin-2,3-dioxygenase
MTRYRDVLELHTGHPASDGAGVRLTRVIGGPSPERFDPFLMLDQFDTQNPDDYVAGFPSHPHRGFETVTYMLEGRMRHEDHLGNRGLLKPGGVQWMTAAHGIIHSEMPEQVEGAMRGFQLWVNLPAKNKLAPAGYRDIEPEDVPRLETAGGVKVTVIAGRFDDGQAQQIGAVERPDTEPHYYDLQLPAGGRIAPRLPDGHRVLLYVYEGSLTVEGERPVEIATNRLARLSEEGELSLRSEAGARVLVLAGKPLREPIVQYGPFVMNSREEIEQALRDYRDGVLAV
>CP030910.1|AXL70473.1|2734537_2735662_+|hypothetical-protein
MPIQTLATLADIDAAEWDALLPPAQPFLRHAFLSALEDSHSVTPATGWRPAHRVLRDPQGRLCAALPAYVKAHSYGEYVFDWSWADACQRAGIRYYPKLLVGVPFTPVAGARLLGEDEGLQGLLASLGEEAEASGLSSIHVNFTDARADTLLAARDGWLERLGCQYHWHNRGYRDFQDFLEALSSRKRKQLRKEREQVGGQGIEFEWREGGQLSELEWDFVYLCYANTYLVRDRDPYLSREFFGLLAERMPEAIRVVFAHQRGKPVAMAFSLVAGDTLYGRYWGCLAEFDRLHFETCFYQGLEFAIGAGLARFDAGAQGEHKLIRGFEPVLTRSWHYLAHPGLRDAVAQFLEQERAGVRAYAEEAHGLLPYRQA
>CP030910.1|AXL70474.1|2735694_2735961_-|hypothetical-protein
MKLASVVSAVITSLAPMAFAQDVDKDPGRGLPVEEYHYGMQLDVKNVLHRTDNSTRTGVVPVTVVYEDHSGELHKIRFLEWGGSTSNG
>CP030910.1|AXL70475.1|2736242_2738075_-|ABC-transporter-ATP-binding-protein/permease
MLYRRFERLIDPFRSASERMPPSEVLRFYVYFLRQVWPVFLALLVVGLIVALIEVALFSYLGRIVDLAQSTPSAEFFRVHANELIWMAVVALVLRPLFNALHDMLVHQSINPSMTNLIRWQNHRYVLKQSLGFFQNDFAGRIAQRIMQTGNSLRDSAVQVVDALWHVLIYTVSALVLFAEADWRLMIPLVLWVFAYVGALAYFVPQVKRRSVEASDSRSKLMGRIVDGYTNITTLKLFAHTRQEEDYAREAIGDQTLKSQRAGRVVTSMDVTITVMNGVLITGTTGLALWLWSQELISVGAIALATGLVIRINNMSGWIMWVVGGIFENIGQVQDGMQTIALPRKVVDREDAQPLRVERGEVEFEHIAFHYGKGSGVIQGLDLKVRPGEKIGLVGPSGAGKSTLVNLLLRLYDLESGRILVDGQDIAGVTQESLRAQIGMVTQDTSLLHRSIRDNLLYGRPGASDAELMEAVRKARADEFIPLLSDAEGRRGFDAHVGERGVKLSGGQRQRIAIARVLLKDAPILILDEATSALDSEVESAIQESLETLMQGKTVIAIAHRLSTIARMDRLVVLDKGHIAESGTHAELLAHGGLYARLWQHQTGGFVGVD
>CP030910.1|AXL70476.1|2738137_2738701_-|Peptidyl-prolyl-cis-trans-isomerase-A
MLKRLLIAACTLLFAGSLLAATPAAKPHVLIATSLGEIEVELDPAKAPISVKNFLEYVDSGYYDGTLFHRVIPGFMVQTGGFSAGMQEKKTRAPIKNEADNGLLNERGTLAMARTGVVDSATSQFFINLTDNDFLNHGARDFGYAVFGKVVRGMGVVDQIAKVPTTRRNGFADVPSDDVVILSAKRL
>CP030910.1|AXL70477.1|2738682_2739510_-|Beta-ketoadipate-enol-lactone-hydrolase
MPDFQHRDCTLVYDDHPGPTERAPVLLLHGLGSSARDWEYQLPALLGHYRLLVPDLRGHGRSGKPRGGYSMAGFAEDCAALLDRLGCGPVHLVGISMGGMIGFQLACDRPDLLRSLTIVNSTPEVIPRKPREHLEVAKRKLLSRLLSLRTIGRALGRLLFPKAEQAGLREKIEARWAENDKRAYLASLDAIIGWGVQERLAEIACPTLVISADRDYTPVSLKQAYCERIADARLVVVEDSRHATPMDQPEIFNTTLLGFLADIDKTKEQPCSNVS
>CP030910.1|AXL70478.1|2739516_2740446_-|LysR-family-transcriptional-regulator
MKAPRVTLDQWRTLQAVVDHGGFAQAAEALHRSQSSISYTVARMQEQLGVPLLRIDGRKAVLTEAGEVLLRRSRQLVKQAGQLEELAHHMEQGWEPEVRLVVDAAYPTARIVRSLSAFMPQSRGCRVLLREEVLSGVEEALIQGAADLAISGLIIPGHLGADLSVVEFVAVAHPDHPLHRLQRELTHQDLETQMQVVIRDSGRLQPRDHGWLGAEQRWTVGSLATAATFVGNGLGFAWLPRHIIERELQSGQLKPLPLSQGGVRQSRFYLYTNKEKPLGPASQILMEMLKSFANVPLNAPFAAPEPAAE
>CP030910.1|AXL70479.1|2740645_2740963_+|3-phosphoglycerate-kinase
MKRLCCFALSLLPLSAFAYPIEVDPQLNGTEVSYSTQDIGRDMGAILLTNLGGQAAECTAVFRNGPETPKVRKGVIQPGQNSNFTAQFGRDIIKLRIKLTCKIAK
>CP030910.1|AXL70480.1|2741109_2741751_+|FMN-dependent-NADH-azoreductase-3
MSRVLVIESSARQRGSVSRLLTAEFISHWKIAHPADRFQVRDLAREPLPHLDELLLGAWTTPCDGHSAAERRALERSNRLTEELRMADVLVLAAPMYNFAIPSSLKSWFDHVLRAGLTFRYAEQGPEGLLQGKRAFVLTARGGIYAGGGLDHQEPYLRQVLGFVGIHDVTFIHAEGMNMGPEFREKGLARARERMRQALETDTSLCVPLPTLR
>CP030910.1|AXL70481.1|2741876_2742755_-|Permease
MNRRSALAALHGGALLFGLTGVFGKLASASPGVIVFGRALFAVLALGLFARLAGQAWRALGPAQWLRLALCGLLLAGHWVSFFIAVKTAGVAIATLGFASFPAFTVILEGLLFRERIHLAEGLLVVLVSLGLVLVTPNFDLASGATLGLLWAILSGLLFALLSLANRSNSGQVGPVQAALWQNLVVTLCLLPFAVGELPVLPALDWLWLALLGVFCTGLAHSLFVASLAVVKARTAALVFALEPVYGIAFAWLLFHETPGPRMFLGGALIILAIVLSARLGARGRKTAVGDE
>CP030910.1|AXL70482.1|2742764_2743100_-|Export-related-chaperone-CsaA-family-protein
MDIIEWQDFERVELRVGTILSAAPNPKARKPAYVLEVDLGPLGLRTSSAQLTAHYQAEQLVGRQVLCVCNFAPKQIAGVRSEVLVTGVYDSEDKVVLAGFDKPLPNGARLA

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Crispr_ID: CP030910_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030910_3

4589864-4590035

Orphan

Consensus_repeat	Method
TATCCGCCATGAAACGCCAGCGCAGCGG	CRISPRCasFinder

2 spacers

The CRISPR arrays of CP030910_3

>merge|CP030910|3|4589864-4590035|CRISPRCasFinder
TACCCACCATGAAACGGGTGGGCTTCGAGGCCGCGTAGGGCGAATAACCGCTTGCGGTTATCCGCCATGAAACGCCAGCGCAGCGGCGGATAACGCCGGTGGCGTTATTCGCCCTACGGCCCGGCTCCGGGGCCGCGGGACGCATATCCGCCATGAAACGCCGGCGCAGCGG

>CP030910|3|3|4589864-4590035|CRISPRCasFinder
TACCCACCATGAAACGGGTGGGCTTCGA	GGCCGCGTAGGGCGAATAACCGCTTGCGGT
TATCCGCCATGAAACGCCAGCGCAGCGG	CGGATAACGCCGGTGGCGTTATTCGCCCTACGGCCCGGCTCCGGGGCCGCGGGACGCA
TATCCGCCATGAAACGCCGGCGCAGCGG

Protein	Signature genes	Signature genes Name	Protein_function
CP030910.1\|AXL72128.1\|4596795_4597509_-\|Bacterial-regulatory-s,-luxR-family-protein	unknown	unknown	gnl\|CDD\|377050
CP030910.1\|AXL72123.1\|4591560_4593444_-\|anthranilate-synthase	unknown	unknown	gnl\|CDD\|223225
CP030910.1\|AXL72129.1\|4598270_4599038_+\|desaturase	unknown	unknown	gnl\|CDD\|225546
CP030910.1\|AXL72116.1\|4585028_4586180_+\|Peptidase	unknown	unknown	gnl\|CDD\|225723
CP030910.1\|AXL72117.1\|4586176_4586365_+\|hypothetical-protein	unknown	unknown	unknown
CP030910.1\|AXL72112.1\|4580142_4580823_+\|hypothetical-protein	unknown	unknown	unknown
CP030910.1\|AXL72125.1\|4594060_4595278_-\|Phenazine-biosynthesis-protein-PhzC	unknown	unknown	gnl\|CDD\|225741
CP030910.1\|AXL72119.1\|4587574_4589215_+\|Dienelactone-hydrolase	unknown	unknown	gnl\|CDD\|226651
CP030910.1\|AXL72127.1\|4595825_4596314_-\|Phenazine-biosynthesis-protein-PhzA	unknown	unknown	gnl\|CDD\|367435
CP030910.1\|AXL72113.1\|4580914_4581421_+\|RNA-polymerase-sigma-factor,-sigma-70-family-protein	unknown	unknown	gnl\|CDD\|171561
CP030910.1\|AXL72115.1\|4582576_4584988_+\|TonB-dependent-receptor-protein	unknown	unknown	gnl\|CDD\|238657
CP030910.1\|AXL72120.1\|4589257_4589794_+\|Hydrolase	unknown	unknown	gnl\|CDD\|223611
CP030910.1\|AXL72124.1\|4593440_4594064_-\|Phenazine-biosynthesis-protein-PhzD	unknown	unknown	gnl\|CDD\|238495
CP030910.1\|AXL72130.1\|4599043_4600213_+\|hypothetical-protein	unknown	unknown	unknown
CP030910.1\|AXL72111.1\|4579844_4580036_+\|Halovibrin	unknown	unknown	gnl\|CDD\|378494
CP030910.1\|AXL72121.1\|4590040_4590688_-\|Phenazine-biosynthesis-protein	unknown	unknown	gnl\|CDD\|223337
CP030910.1\|AXL72122.1\|4590710_4591547_-\|Trans-2,3-dihydro-3-hydroxyanthranilate-isomerase	unknown	unknown	gnl\|CDD\|334973
CP030910.1\|AXL72118.1\|4586366_4587578_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340888
CP030910.1\|AXL72126.1\|4595301_4595790_-\|Phenazine-biosynthesis-protein-PhzB-2	unknown	unknown	gnl\|CDD\|367435
CP030910.1\|AXL72114.1\|4581417_4582368_+\|Transmembrane-sensor	unknown	unknown	gnl\|CDD\|226235

Protein	Function_ID	Function_description	E-value
CP030910.1\|AXL72128.1\|4596795_4597509_-\|Bacterial-regulatory-s,-luxR-family-protein	gnl\|CDD\|377050	pfam03472, Autoind_bind, Autoinducer binding domain. This domain is found a a large family of transcriptional regulators. This domain specifically binds to autoinducer molecules.	3.47942e-42
CP030910.1\|AXL72123.1\|4591560_4593444_-\|anthranilate-synthase	gnl\|CDD\|223225	COG0147, TrpE, Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism].	3.6522e-82
CP030910.1\|AXL72129.1\|4598270_4599038_+\|desaturase	gnl\|CDD\|225546	COG3000, ERG3, Sterol desaturase [Lipid metabolism].	1.13085e-45
CP030910.1\|AXL72116.1\|4585028_4586180_+\|Peptidase	gnl\|CDD\|225723	COG3182, PiuB, Uncharacterized iron-regulated membrane protein [Function unknown].	1.1322e-94
CP030910.1\|AXL72125.1\|4594060_4595278_-\|Phenazine-biosynthesis-protein-PhzC	gnl\|CDD\|225741	COG3200, AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism].	0
CP030910.1\|AXL72114.1\|4581417_4582368_+\|Transmembrane-sensor	gnl\|CDD\|226235	COG3712, FecR, periplasmic ferric-dicitrate binding protein FecR, regulates iron transport through sigma-19 [Inorganic ion transport and metabolism, Signal transduction mechanisms].	3.62392e-93
CP030910.1\|AXL72119.1\|4587574_4589215_+\|Dienelactone-hydrolase	gnl\|CDD\|226651	COG4188, COG4188, Predicted dienelactone hydrolase [General function prediction only].	8.27522e-71
CP030910.1\|AXL72113.1\|4580914_4581421_+\|RNA-polymerase-sigma-factor,-sigma-70-family-protein	gnl\|CDD\|171561	PRK12528, PRK12528, RNA polymerase sigma factor; Provisional.	1.95845e-60
CP030910.1\|AXL72115.1\|4582576_4584988_+\|TonB-dependent-receptor-protein	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	2.26217e-117
CP030910.1\|AXL72120.1\|4589257_4589794_+\|Hydrolase	gnl\|CDD\|223611	COG0537, Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only].	8.89532e-15
CP030910.1\|AXL72124.1\|4593440_4594064_-\|Phenazine-biosynthesis-protein-PhzD	gnl\|CDD\|238495	cd01013, isochorismatase, Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological systems. Isochorismatase is part of the phenazine biosynthesis pathway. Phenazines are antimicrobial compounds that provide the competitive advantage for certain bacteria.	8.51915e-130
CP030910.1\|AXL72122.1\|4590710_4591547_-\|Trans-2,3-dihydro-3-hydroxyanthranilate-isomerase	gnl\|CDD\|334973	pfam02567, PhzC-PhzF, Phenazine biosynthesis-like protein. PhzC/PhzF is involved in dimerization of two 2,3-dihydro-3-oxo-anthranilic acid molecules to create PCA by P. fluorescens. This family also contains uncharacterized Mycobacterial proteins, though there is no significant sequence similarity to pfam00303 members. This family appears to be distantly related to pfam01678, including containing a weak internal duplication. However members of this family do not contain the conserved cysteines that are hypothesized to be active site residues (Bateman A pers obs).	4.89388e-112
CP030910.1\|AXL72121.1\|4590040_4590688_-\|Phenazine-biosynthesis-protein	gnl\|CDD\|223337	COG0259, PdxH, Pyridoxamine-phosphate oxidase [Coenzyme metabolism].	2.00814e-99
CP030910.1\|AXL72127.1\|4595825_4596314_-\|Phenazine-biosynthesis-protein-PhzA	gnl\|CDD\|367435	pfam03284, PHZA_PHZB, Phenazine biosynthesis protein A/B.	4.33555e-101
CP030910.1\|AXL72118.1\|4586366_4587578_+\|MFS-transporter	gnl\|CDD\|340888	cd17330, MFS_SLC46_TetA_like, Eukaryotic Solute carrier 46 (SLC46) family, Bacterial Tetracycline resistance proteins, and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of the eukaryotic proteins MFSD9, MFSD10, MFSD14, and SLC46 family proteins, as well as bacterial multidrug resistance (MDR) transporters such as tetracycline resistance protein TetA and multidrug resistance protein MdtG. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. TetA proteins confer resistance to tetracycline while MdtG confers resistance to fosfomycin and deoxycholate. The Solute carrier 46 (SLC46) family is composed of three vertebrate members (SLC46A1, SLC46A2, and SLC46A3), the best-studied of which is SLC46A1, which functions both as an intestinal proton-coupled high-affinity folate transporter involved in the absorption of folates and as an intestinal heme transporter which mediates heme uptake. MFSD10 facilitates the uptake of organic anions such as some non-steroidal anti-inflammatory drugs (NSAIDs) and confers resistance to such NSAIDs. The SLC46/TetA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.23268e-60
CP030910.1\|AXL72126.1\|4595301_4595790_-\|Phenazine-biosynthesis-protein-PhzB-2	gnl\|CDD\|367435	pfam03284, PHZA_PHZB, Phenazine biosynthesis protein A/B.	4.11013e-107
CP030910.1\|AXL72111.1\|4579844_4580036_+\|Halovibrin	gnl\|CDD\|378494	pfam10783, DUF2599, Protein of unknown function (DUF2599). This family is conserved in Actinobacteria. The function is not known.	5.01848e-19

>CP030910.1|AXL72120.1|4589257_4589794_+|Hydrolase
MHIPPELIIHQTRHWTLNQRIDSALPGYCMLGSRQPATAFHQLPEQALAEFGPLLARVEREMDALLRPRRIYVGRYGHMPGLPVHFHLIPLYDWVEELFWEDTRYRTLQQFGMPTAEPLTDGAELTLFVWREFCERADPPAVRGMDRQQAIAGLRRAFGYGVQPRTSPGPDSEPAQGA
>CP030910.1|AXL72119.1|4587574_4589215_+|Dienelactone-hydrolase
MTAVDLLLVATLLAALLAWWIPALPGRRGLLALASTLALGAGLYAAWDDRWQAGVGAFAGFSLLLGACLRRKPERGLPFRTGSLYGLLVLLAIAALYLFPVAPLPAPSGPYAVGVRDFELDDPSRPGLLGTPAGQPRRLLVRAWYPARPIAGAAPRHYFDPGEARSTARGFGEILGFPPLLTYLKHLRTNSYPDAPLRDDSARLPVVFYSHGYSAFAGGNWTLMEELASHGYAVYAIQHSGDASPTRLPDGTLLPMDPGLVEHLRRAAHDGLPQAMRQGYVSDDLDQRLDGQLHTALDLPAPANRAVNLSAPVWLADRLFVHDRLQAGEVPDRVADLVAASDFAHTGEMGMSFGGSTTGAVCMVDRRCAAAVNLDGGDFDFAPFDSDFPAPLLMLHADLGNFYRLFGIEPPARPRSFNDFSYERFEHAGQRQDIHRLVLRDSAHAGLTDNPLFIRRPLRDGLLGSAPTEILIQAPNTLVLGFFDHYLRGRANDFPQAQMARFPAWLTRYDNSAVRDWWLAKPEAQRLALRQRIDEMKRRKTGLDLP
>CP030910.1|AXL72118.1|4586366_4587578_+|MFS-transporter
MTTPPPSANTLDLRPLMFETFVCTLAVMSFVALVGPLARKLGLAPWQAGAAVTVGGIAWMLAARPWGIASDRHGRRRILLGGLAGFALSYGSLCLFIVLALHWTLPTLLAFAGIVLLRGLAGGFYAAVPACTAALVADHVEAQRRAAALAGLGAASAIGMVIGPGLAGLLATHGLVLPLLVTGALPLVALLALWRWLPREERRQPNRGAALAIGDRRLRRPLAVGFVAMFSVTVAQITVGFFALDRLRLDSADAARVAGIALTAVGVALILAQLLVRRLDWPPPRLIRVGGLVAAIGFAAVCFADSPPLLWLAFFVAAAGMGWVFPAVSALNANAVRAEEQGAAAGTLVAVHGFGLISGPLLGALLHQLDSRAPYALVGLLLALAAFWPSQPTRPVETRSEAP
>CP030910.1|AXL72117.1|4586176_4586365_+|hypothetical-protein
MRRGLWMIFRWPLLLALLGLFGLLSALLGDGLYDLLSWLALGTPLVLVGWVWLRLPRTRRNP
>CP030910.1|AXL72116.1|4585028_4586180_+|Peptidase
MTAKTLRTWYLVHKWTSLISTIFLLMLCLTGLPLIFHEEIEHYFEPHPQLEPLTAESPRIDYDDVIARALAARPGEVVRFLVFEKDDPLGLVISAPSLVPPPENGHMQPFDARTGEFFDALPPPGGFMYLMLKLHTDLFLGLPGYLFLGLMGLLLVASLVSGVVVYTPFMRKLDFATVRAERSRRLKWLDLHNLLGIVTLSWVLVVGVTGVINTLALPILILWQGGQLAEMTAPYKDAPPLQRLGSLDAALATARRAAPDMEVSFVGFPGTQFSSQHHYAVFMRGNTPLTERLLKPALIDAQTGELTDMREMPLYVKTLLLSQPLHFGDYGGMPLKIVWALLDLVSIVILASGLYLWLGRRKTPLEKRLAELPDGSLATEGKA
>CP030910.1|AXL72115.1|4582576_4584988_+|TonB-dependent-receptor-protein
MPVRTLRPRSLSLAIHAAMTLALAGAAPALLAAEAPAASSARSYDIAPGPLGRTLSAFASDNGVSLAFDPALTEGRRSAALRGRYAPVEALHRLLLGSGLELQQRSDGSYTLVPAATDGALELQSSLITAQAAGAETLPAEYAGGQVARGARLGMLGNADVMDAPFSITSYTARTIEQQQARSVADLLQANDPSVRVVGGRGDLVDSYTIRGFSVQNADVAFNGLYGLLPFWRVPIEFAERVEVLKGPNALLGGISPGGSVGGTINLVPKRADDQPLTRVSVDWTQRGQLGTHLDIGRRFGENNAFGVRFNGVYRNGDTAVDHQSREFPMLSLGLDFRGERLRLSSDLLYQKESLEGVVRPLLTGPGTTHIPHAPDSKTRFGLRDSYLDQEDYSMVNRGEYDLADNLTAFASIGGRQSNYETIAANSILVGNQGDIVNSLARQRGDRRTYSAEVGLRGNFDTGPLRHDWTLSANRLHERLGMVYAFTGMQPGNLYQTSPHTPLPDFSSLDGSIPKTNETDLGGVALADRLSFLEDRVQVTLGVRRQQIESRNYDQTSGARTSHDKRHVWTPMASVLVKPLQDLSLYANYIQGLSQGEAAPMTAANAGQVLAPYKAEQYEIGAKYDLGGFTTTLALFEIRKPNAYTDASNVFRADGEQRNRGVELSLYGEPLDGVRVMAGATYIKPEQNKTGDPASEGKDAPGVARRQANLGVSWDTPFVDGLTLDSRWIYTGSAYVDSANALAVPHWNRVDLGAAYAFQVAGKPLVARANLENALGKDYWTAANGYLSISSPRTLSLSLTADF
>CP030910.1|AXL72114.1|4581417_4582368_+|Transmembrane-sensor
MSSAGEGRIPSPILDEAAEWLVRLQDSGCTDDTRQACAQWRQRSPQHAHAWERAERLLQCLGRLPPALALPTLGRERGLDRRRAIKHLALVLGGASLGLATWQAEPLRDWLADQRTGVGEQRRLTLPDGSLLTLNTDSAVDLAFDASQRLVRLLRGEIFVDSRADPRPFRVATAEARLHAGAARFNVRQEMAATRVAVLAGRVELSPLHGRGRWLESGESVRLGTDGEARRLAFDGLPDAWTRGMLMADRMPLAEVLAELARYRRGLLRCDPQLARLAVSGAYPLLDLRRTLGMLQATYPLKVRGVTDYWISLVPA
>CP030910.1|AXL72113.1|4580914_4581421_+|RNA-polymerase-sigma-factor,-sigma-70-family-protein
MPPADASLHDAVSHLYQDHHGWLQGWLRRRLGCAENAADLAQDTFARLLASRRVLDAREPRAYLTTVAKGLMINWFQRQSLERAYLDALANLPEDLAPPPEQRLMVLETLHEVDALLGSLPDRVRQAFLLAQIEGLKYEAIAERLGVSLGSVKRYMQQAFRQCLELME
>CP030910.1|AXL72112.1|4580142_4580823_+|hypothetical-protein
MAFDAARYVHRYYASLAPAPGNEYPRLRAWEYLWEYVWDPSRSWDDLTAPEQLDTTALHLGFYLANWGMFRGSSGLLQNSNLDLMKALARQLFSGAGAELFELSLVDFAGNGARLAHNRKLLETVLGSMDALSSRVSWTDTLKSKILLGVWGEFPALDRHYLAACRALYPRRGLTSVNGGTLTALHRLIGEERLSFPRLETARKGLLYPTGRLADMAFFQYGLENA
>CP030910.1|AXL72111.1|4579844_4580036_+|Halovibrin
MVDHYLDSEWKDNPDNRDSNIGSMRRQLVCHFNVARNKPEWNLEPSRPYTSNEDSIAKGCNNT
>CP030910.1|AXL72121.1|4590040_4590688_-|Phenazine-biosynthesis-protein
MMGVNANISESLTGTIEAPFPEFEAPPANPMEVLRNWLERARRYGVREPRALALATVDGQGRPSTRIVVIAELGERGVVFATHADSQKGRELAQNPWASGVLYWRESSQQIILNGRAERLPDERADAQWLSRPYQTHPMSIASRQSETLADIHALRAEARRLAETDGPLPRPPGYCLFELCLESVEFWGNGTERLHERLRYDRDEGGWKHRYLQP
>CP030910.1|AXL72122.1|4590710_4591547_-|Trans-2,3-dihydro-3-hydroxyanthranilate-isomerase
MHRYVVIDAFASEPLQGNPVAVFFDCDDLSGERMQRMAREMNLSESTFVLRPQQDGDARIRIFTPVNELPFAGHPLLGTAIALGAETDKDRLFLETRMGTVPFALERQDGKVVACSMQQPIPTWEHFSRPAELLAALGLKGSTFPIEVYRNGPRHVFVGLESVAALSALHPDHRALCDFPDLAVNCFAGAGRHWRSRMFSPAYGVVEDAATGSAAGPLAIHLARHRQIPYGQQIEILQGVEIGRPSRMYARAEGAGERVSAVEVSGNGAAFAEGRAYL
>CP030910.1|AXL72123.1|4591560_4593444_-|anthranilate-synthase
MNALPTSLLQRLLERPAPFALLYRPESNGPGLLDVIRGEALELHGLADLPLDEPGPGLPRHDLLALIPYRQIAERGFEALDDGTPLLALKVLEQELLPLEQALALLPNQALELSEEAFDLDDEAYAEVVGRVIADEIGRGEGANFVIKRRFQARIDGYATASALSFFRQLLLREKGAYWTFIVHTGERTLVGASPERHISVRDGLAVMNPISGTYRYPPAGPNLAEVMEFLDNRKEADELYMVVDEELKMMARICEDGGRVLGPYLKEMAHLAHTEYFIEGQTSRDVREVLRETLFAPTVTGSPLESACRVIRRYEPQGRGYYSGVAALIGGDGQGGRTLDSAILIRTAEIEGDGRLRIGVGSTIVRHSDPLGEAAESRAKASGLIAALKSQAPQRLGSHPHVVAALASRNAPIADFWLRGASERQQLQADLSGREVLIVDAEDTFTSMIAKQLKSLGLTVTVRGFQEPYSFDGYDLVIMGPGPGNPTEIGQPKIGHLHLAIRSLLSERRPFLAVCLSHQVLSLCLGLDLQRRQEPNQGVQKQIDLFGAAERVGFYNTFAARALQDRIEIPEVGPIEISRDRETGEVHALRGPRFASMQFHPESVLTREGPRIIADLLRHALVERRP
>CP030910.1|AXL72124.1|4593440_4594064_-|Phenazine-biosynthesis-protein-PhzD
MSGIPEITAYPLPTAQQLPANLARWSLEPRRAVLLVHDMQRYFLRPLPESLRAGLVANAARLRRWCVEQGVQIAYTAQPGSMTEEQRGLLKDFWGPGMRASPADREVVEELAPGPDDWLLTKWRYSAFFHSDLLQRMRAAGRDQLVLCGVYAHVGVLISTVDAYSNDIQPFLVADAIADFSEAHHRMALEYAASRCAMVVTTDEVLE
>CP030910.1|AXL72125.1|4594060_4595278_-|Phenazine-biosynthesis-protein-PhzC
MDDLLQRVRRCEALQQPEWGDPSRLRDVQAYLRGSPALIRAGDILALRATLARVARGEALVVQCGDCAEDMDDHHAENVARKAAVLELLAGALRLAGRRPVIRVGRIAGQYAKPRSKPHEQVGEQTLPVYRGDMVNGREAHAEQRRADPQRILKGYAAARNIMRHLGWDAASGQEANASPVWTSHEMLLLDYELSMLREDEQRRVYLGSTHWPWIGERTRQVDGAHVALLAEVLNPVACKVGPEIGRDQLLALCERLDPRREPGRLTLIARMGAQKVGERLPPLVEAVRAAGHPVIWLSDPMHGNTIVAPCGNKTRLVRSIAEEVAAFRLAVSGSGGVAAGLHLETTPDDVTECVADSSGLHQVSRHYTSLCDPRLNPWQALSAVMAWSGAEAIPSATFPLETVA
>CP030910.1|AXL72126.1|4595301_4595790_-|Phenazine-biosynthesis-protein-PhzB-2
MLDNAIPQGFEDAVELRRKNRETVVKYMNTKGQDRLRRHELFVEDGCGGLWTTDTGSPIVIRGKDKLAEHAVWSLKCFPDWEWYNIKVFETDDPNHFWVECDGHGKILFPGYPEGYYENHFLHSFELDDGKIKRNREFMNVFQQLRALSIPVPQIKREGIPT
>CP030910.1|AXL72127.1|4595825_4596314_-|Phenazine-biosynthesis-protein-PhzA
MREYQRLKGFTDNLELRRRNRATVEHYMRMKGAERLQRHSLFVEDGCAGNWTTESGEPLVFRGHESLRRLAEWLERCFPDWEWHNVRIFETEDPNHFWVECDGRGKALVPGYPEGYCENHYIHSFELENGRIKRNREFMNPMQKLRALGIAVPQIKRDGIPT
>CP030910.1|AXL72128.1|4596795_4597509_-|Bacterial-regulatory-s,-luxR-family-protein
MHDEREGYLEILSRITTEEEFFSLVLEICGNYGFEFFSFGARAPFPLTAPKYHFLSNYPGEWKSRYISEDYTSIDPIVRHGLLEYTPLIWNGEDFQENRFFWEEALHHGIRHGWSIPVRGKYGLISMLSLVRSSESIAATEILEKESFLLWITSMLQATFGDLLAPRIVPESNVRLTARETEMLKWTAVGKTYGEIGLILSIDQRTVKFHIVNAMRKLNSSNKAEATMKAYAIGLLN
>CP030910.1|AXL72129.1|4598270_4599038_+|desaturase
MIYYLIGVALFIFMLEQLVPGWKLPKVSTWVARVIFLNIVQVSIALLAGITWNKWMMGHSLLHTSDALPPLLAGFAAYFVNTFVTYWWHRARHANDTLWRLFHQLHHAPQRIEVFTSFYKHPTEMVFNSLLGSFVAYVVMGISIEAGAYYIMFAALGEMFYHSNLRTPHVLGYLFQRPEMHRIHHQRDRHECNYSDFPIWDMLFGTYENPRRIDEPQGFAGDKEQQFVDMLLFRDVHSLPGKTQPAPVLVKPDVR
>CP030910.1|AXL72130.1|4599043_4600213_+|hypothetical-protein
MIPDIDSRLSRNILKSISYGLPLAEVVPDHTYAQLETRLGELKRRYLELRISHGARELPFSNYLFYLILQSRHQEFDFKLRQGNSVVTNIHRFKSKGRIPSLTTLLLADAVNAKSELELKHPDIPQLDRHARDIERWLAAGNVMPPSERALRGLVEALERAAGEGRPLHLVSAVCPDYSHSSDAEGKPRYTFERVGDQPGLAGAKLVSAGQAVAELARARQVEIRHAILGGEFEYLSFNRNPATGETREGFLGKVERQLERIAGALPCPAATCSFFEMCGGEDGWHRAHGEIVQRLEQGDYGQTGLDYPALESIFLSRLPLYEKWFASQSREQIWASFVSQAAEYALMGKLFGERFDNFVVLAVDHYRMEPFYSFFATVPTLYIRTDYL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP030910_3	3.1\|4589892\|30\|CP030910\|CRISPRCasFinder	4589892-4589921	30	CP030910.1	1641812-1641841	0	1.0
CP030910_3	3.1\|4589892\|30\|CP030910\|CRISPRCasFinder	4589892-4589921	30	CP030910.1	1983466-1983495	2	0.933

1. spacer 3.1|4589892|30|CP030910|CRISPRCasFinder matches to position: 1641812-1641841, mismatch: 0, identity: 1.0

ggccgcgtagggcgaataaccgcttgcggt	CRISPR spacer
ggccgcgtagggcgaataaccgcttgcggt	Protospacer
******************************

2. spacer 3.1|4589892|30|CP030910|CRISPRCasFinder matches to position: 1983466-1983495, mismatch: 2, identity: 0.933

ggccgcgtagggcgaataaccgcttgcggt	CRISPR spacer
ggcctggtagggcgaataaccgcttgcggt	Protospacer
****  ************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP030910_2	2.1\|2734326\|52\|CP030910\|CRISPRCasFinder	2734326-2734377	52	NZ_CP042268	Pseudomonas aeruginosa strain HOU1 plasmid pHOU1-1, complete sequence	63791-63842	0	1.0

1. spacer 2.1|2734326|52|CP030910|CRISPRCasFinder matches to NZ_CP042268 (Pseudomonas aeruginosa strain HOU1 plasmid pHOU1-1, complete sequence) position: , mismatch: 0, identity: 1.0

tccggcgttattcgccctacgcggagggttcccagctttcgctccgccgttg	CRISPR spacer
tccggcgttattcgccctacgcggagggttcccagctttcgctccgccgttg	Protospacer
****************************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

650232 : 713096

Pseudomonas_phage(24.14%)

plate,tRNA,holin,integrase,tail

attL 645182:645196|attR 681573:681587

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
645182:645196	attL	NA	NA	NA	NA
AXL68565.1\|650232_651309_-\|integrase	Phage integrase	W6MYA3	Pseudomonas_phage	2.8e-46	38.3
AXL68566.1\|651528_655266_-	diguanylate cyclase	A0A127AWB9	Bacillus_phage	4.8e-13	35.4
AXL68567.1\|655372_657226_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.2e-36	33.8
AXL68568.1\|657305_659300_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.8e-73	40.7
AXL68569.1\|659382_659832_-	Yqey-like family protein	A0A292GL36	Xanthomonas_phage	2.9e-18	38.8
AXL68570.1\|659901_660117_-	30S ribosomal protein S21	NA	NA	NA	NA
AXL68571.1\|660317_661343_+\|tRNA	tRNA N6-adenosine threonylcarbamoyltransferase	A0A0R6PI74	Moraxella_phage	8.3e-109	58.1
AXL68572.1\|661421_661991_-	Glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
AXL68573.1\|662011_662428_+	Dihydroneopterin aldolase	NA	NA	NA	NA
AXL68574.1\|662418_662961_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase	NA	NA	NA	NA
AXL68575.1\|662933_664166_-	Multifunctional CCA protein	A0A076G5T8	Escherichia_phage	2.6e-77	43.1
AXL68576.1\|664209_664716_-	hypothetical protein	NA	NA	NA	NA
AXL68577.1\|664809_666363_-	SpoVR family protein	NA	NA	NA	NA
AXL68578.1\|666359_667631_-	hypothetical protein	A0A140HLI1	Bacillus_phage	4.2e-09	37.2
AXL68579.1\|667731_669654_-	serine/threonine protein kinase	NA	NA	NA	NA
AXL68580.1\|669932_670265_-	Thiosulfate sulfurtransferase GlpE	NA	NA	NA	NA
AXL68581.1\|670308_671160_-	Bis(5'-nucleosyl)-tetraphosphatase, symmetrical	A0A2H4J0P0	uncultured_Caudovirales_phage	1.1e-08	33.3
AXL68582.1\|671159_671540_-	Protein ApaG	NA	NA	NA	NA
AXL68583.1\|671576_672383_-	Ribosomal RNA small subunit methyltransferase A	NA	NA	NA	NA
AXL68584.1\|672498_673485_-	4-hydroxythreonine-4-phosphate dehydrogenase 1	NA	NA	NA	NA
AXL68585.1\|673481_674774_-	Chaperone SurA	NA	NA	NA	NA
AXL68586.1\|674754_677544_-	LPS-assembly protein LptD	NA	NA	NA	NA
AXL68587.1\|677670_678687_+	Aminoglycoside phosphotransferase	NA	NA	NA	NA
AXL68588.1\|678683_679358_+	Nucleotidyl transferase	NA	NA	NA	NA
AXL68589.1\|679359_680118_+	DnaJ domain protein	NA	NA	NA	NA
AXL68590.1\|680118_681180_-	Hydrolase or acyltransferase	NA	NA	NA	NA
AXL68591.1\|681331_683725_+	Histidine kinase	NA	NA	NA	NA
681573:681587	attR	NA	NA	NA	NA
AXL68592.1\|683770_684403_+	Bacterial regulatory s, luxR family protein	NA	NA	NA	NA
AXL68593.1\|684531_685566_+	Bacterial extracellular solute-binding family protein	NA	NA	NA	NA
AXL68594.1\|685799_686909_+	Polyamine ABC transporter, ATP-binding family protein	G3M9Y6	Bacillus_virus	7.8e-28	34.4
AXL68595.1\|686964_688011_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AXL68596.1\|688124_689372_+	Polyamine ABC transporter substrate-binding protein	NA	NA	NA	NA
AXL68597.1\|689477_690308_+	Binding--dependent transport system inner membrane component family protein	NA	NA	NA	NA
AXL68598.1\|690431_691106_+	Ribulose-phosphate 3-epimerase	NA	NA	NA	NA
AXL68599.1\|691105_691924_+	Phosphoglycolate phosphatase	NA	NA	NA	NA
AXL68600.1\|691996_693475_+	Anthranilate synthase subunit I	NA	NA	NA	NA
AXL68601.1\|693792_694107_-	Transcription regulatory protein PrtN	NA	NA	NA	NA
AXL68602.1\|694206_694977_-	HTH-type transcriptional regulator PrtR	A0A1B0Z078	Pseudomonas_phage	2.3e-71	59.1
AXL68603.1\|695061_695232_-	hypothetical protein	NA	NA	NA	NA
AXL68604.1\|695682_696042_+	hypothetical protein	NA	NA	NA	NA
AXL68605.1\|696500_696854_+\|holin	holin	B5TK61	Pseudomonas_phage	3.0e-26	53.3
AXL68606.1\|696875_697391_+	hypothetical protein	A0A2H4J881	uncultured_Caudovirales_phage	4.1e-32	42.9
AXL68607.1\|697387_697945_+\|plate	Phage baseplate assembly V family protein	A0A2H4JG06	uncultured_Caudovirales_phage	4.6e-45	71.1
AXL68608.1\|698097_698424_+	Bacteriophage protein	A0A2H4JA09	uncultured_Caudovirales_phage	2.4e-30	60.2
AXL68609.1\|698420_699308_+\|plate	Phage baseplate assembly protein	S4TNY7	Salmonella_phage	5.3e-88	59.8
AXL68610.1\|699300_699834_+	Bacteriophage protein	Q9ZXK7	Pseudomonas_virus	3.9e-62	64.6
AXL68611.1\|699835_701941_+\|tail	Phage tail fiber protein	Q9ZXK6	Pseudomonas_virus	5.1e-222	52.7
AXL68612.1\|701948_702389_+\|tail	Phage tail protein	NA	NA	NA	NA
AXL68613.1\|702431_703592_+	Tail protein	Q38068	Phage_PS17	2.0e-188	83.2
AXL68614.1\|703604_704108_+\|tail	Phage major tail tube protein	Q7M2A5	Pseudomonas_phage	8.0e-65	73.5
AXL68615.1\|704122_704467_+	Mu-like prophage FluMu gp41 family protein	NA	NA	NA	NA
AXL68616.1\|704636_706874_+\|tail	Phage tail length determinator protein	NA	NA	NA	NA
AXL68617.1\|706883_707756_+	Phage P2 GpU family protein	A0A2H4J875	uncultured_Caudovirales_phage	2.5e-74	51.4
AXL68618.1\|707730_707937_+	Phage Tail Protein X family protein	A0A2H4J9Z9	uncultured_Caudovirales_phage	2.3e-18	64.2
AXL68619.1\|707994_708984_+	Phage late control protein	A0A2H4JBF6	uncultured_Caudovirales_phage	7.5e-107	55.8
AXL68620.1\|709016_709646_+	Chitinase class I family protein	A0A125RNP1	Pseudomonas_phage	1.6e-86	78.0
AXL68621.1\|709642_710005_+	hypothetical protein	H2BDA0	Pseudomonas_phage	4.2e-15	47.9
AXL68622.1\|710001_710259_+	Lipoprotein	A0A125RNP3	Pseudomonas_phage	8.3e-18	64.6
AXL68623.1\|710606_711212_+	Anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	6.0e-75	65.8
AXL68624.1\|711213_712263_+	Anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	1.8e-111	57.8
AXL68625.1\|712259_713096_+	Indole-3-glycerol phosphate synthase	A0A0P0IR83	Acinetobacter_phage	2.1e-70	56.9

DBSCAN-SWA_2

797544 : 804017

Pseudomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXL68694.1\|797544_797979_+	DNA-Binding protein G5P	Q56VP5	Pseudomonas_phage	1.2e-61	98.6
AXL68695.1\|797995_798088_+	hypothetical protein	Q56VP4	Pseudomonas_phage	7.3e-09	100.0
AXL68696.1\|798099_798351_+	hypothetical protein	NA	NA	NA	NA
AXL68697.1\|798364_798583_+	hypothetical protein	NA	NA	NA	NA
AXL68698.1\|798953_799847_+	Coat protein	NA	NA	NA	NA
AXL68699.1\|799856_800207_+	hypothetical protein	Q56VP0	Pseudomonas_phage	6.0e-19	40.2
AXL68700.1\|800208_801471_+	hypothetical protein	Q56VN9	Pseudomonas_phage	3.7e-119	56.9
AXL68701.1\|801481_801592_+	hypothetical protein	NA	NA	NA	NA
AXL68702.1\|801729_803022_+	hypothetical protein	Q56VN8	Pseudomonas_phage	2.8e-247	94.2
AXL68703.1\|803021_804017_+	hypothetical protein	Q56VN7	Pseudomonas_phage	3.6e-93	52.6

DBSCAN-SWA_3

2310757 : 2319819

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXL70094.1\|2310757_2311426_+	Protein-L-isoaspartate O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	3.0e-43	53.1
AXL70095.1\|2311471_2312365_+	Metalloendopeptidase	A0A0S2SXL7	Bacillus_phage	3.0e-06	34.3
AXL70096.1\|2312469_2313474_+	RNA polymerase sigma factor RpoS	G8CLC7	Synechococcus_phage	7.0e-36	37.3
AXL70097.1\|2313900_2314224_-	Ferredoxin 1	NA	NA	NA	NA
AXL70098.1\|2314290_2316858_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	3.2e-24	22.1
AXL70099.1\|2318138_2318645_+	Protein in recA 5'region	B5TK85	Pseudomonas_phage	8.1e-57	76.0
AXL70100.1\|2318778_2319819_+	Protein RecA	A0A0S2MVG1	Bacillus_phage	1.5e-113	59.5

DBSCAN-SWA_4

3550532 : 3557426

uncultured_Caudovirales_phage(83.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXL71241.1\|3550532_3551813_+\|tRNA	Serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	4.1e-97	45.2
AXL71242.1\|3551814_3553212_+	Siroheme synthase	NA	NA	NA	NA
AXL71243.1\|3553216_3554191_-	Glutathione S-transferase	NA	NA	NA	NA
AXL71244.1\|3554278_3555262_-	Glycosyl transferase, family 3	A0A2H4JBY5	uncultured_Caudovirales_phage	1.6e-141	74.0
AXL71245.1\|3555258_3555594_-	Sulfurtransferase	A0A2H4J8B6	uncultured_Caudovirales_phage	1.5e-38	69.4
AXL71246.1\|3555590_3555896_-	DsrH family protein	NA	NA	NA	NA
AXL71247.1\|3555895_3556255_-	Sulfur relay protein TusC	A0A2H4J8C0	uncultured_Caudovirales_phage	1.4e-34	61.7
AXL71248.1\|3556251_3556647_-	Sulfur transfer complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	4.5e-47	71.3
AXL71249.1\|3556757_3557426_-	HflBKC-binding inner membrane protein	A0A2H4JFM9	uncultured_Caudovirales_phage	5.1e-91	82.5

DBSCAN-SWA_5

5360244 : 5367673

Pseudomonas_phage(85.71%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXL72838.1\|5360244_5361069_-\|tRNA	tRNA 2-thiocytidine biosynthesis protein TtcA	A0A0U2S5Z2	Escherichia_phage	1.4e-106	73.7
AXL72839.1\|5361174_5362191_-	Integrase	Q56VN7	Pseudomonas_phage	5.0e-191	99.7
AXL72840.1\|5362190_5363489_-	hypothetical protein	Q56VN8	Pseudomonas_phage	6.5e-260	99.5
AXL72841.1\|5363625_5363736_-	hypothetical protein	NA	NA	NA	NA
AXL72842.1\|5363746_5365009_-	hypothetical protein	Q56VN9	Pseudomonas_phage	7.5e-120	57.0
AXL72843.1\|5365010_5365361_-	hypothetical protein	Q56VP0	Pseudomonas_phage	5.5e-20	41.1
AXL72844.1\|5365370_5366264_-	Coat protein	NA	NA	NA	NA
AXL72845.1\|5366634_5366853_-	hypothetical protein	NA	NA	NA	NA
AXL72846.1\|5366866_5367118_-	hypothetical protein	NA	NA	NA	NA
AXL72847.1\|5367129_5367222_-	hypothetical protein	Q56VP4	Pseudomonas_phage	7.3e-09	100.0
AXL72848.1\|5367238_5367673_-	DNA-Binding protein G5P	Q56VP5	Pseudomonas_phage	3.8e-63	100.0

DBSCAN-SWA_6

5757436 : 5764718

Pseudomonas_phage(85.71%)

integrase

attL 5756861:5756920|attR 5768779:5768860

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
5756861:5756920	attL	NA	NA	NA	NA
AXL73205.1\|5757436_5758438_-\|integrase	Putative integrase	F1BUS9	Erwinia_phage	2.9e-74	46.5
AXL73206.1\|5758434_5759727_-	hypothetical protein	Q56VN8	Pseudomonas_phage	8.8e-241	92.0
AXL73207.1\|5759864_5759975_-	hypothetical protein	NA	NA	NA	NA
AXL73208.1\|5759985_5761248_-	hypothetical protein	Q56VN9	Pseudomonas_phage	3.7e-119	56.9
AXL73209.1\|5761249_5761600_-	hypothetical protein	Q56VP0	Pseudomonas_phage	6.0e-19	40.2
AXL73210.1\|5761609_5762503_-	Coat protein	NA	NA	NA	NA
AXL73211.1\|5762873_5763092_-	hypothetical protein	NA	NA	NA	NA
AXL73212.1\|5763105_5763357_-	hypothetical protein	NA	NA	NA	NA
AXL73213.1\|5763368_5763461_-	hypothetical protein	Q56VP4	Pseudomonas_phage	7.3e-09	100.0
AXL73214.1\|5763477_5763912_-	DNA-Binding protein G5P	Q56VP5	Pseudomonas_phage	4.3e-59	95.8
AXL73215.1\|5764427_5764718_-	hypothetical protein	Q56VP7	Pseudomonas_phage	4.3e-55	97.9
5768779:5768860	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP030910

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection