CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
CP031286	Escherichia fergusonii strain 40A plasmid p80_40A, complete sequence	0 crisprs	NA	0	0
CP031283	Escherichia fergusonii strain 40A plasmid p150_40A, complete sequence	0 crisprs	csa3,c2c9_V-U4,cas14i,RT	0	0
CP031285	Escherichia fergusonii strain 40A plasmid p46_40A, complete sequence	0 crisprs	NA	0	0
CP031282	Escherichia fergusonii strain 40A chromosome, complete genome	4 crisprs	c2c9_V-U4,cas14i,DEDDh,cas2,cas1,cse2gr11,cas3,csa3	12	5
CP031284	Escherichia fergusonii strain 40A plasmid p280_40A, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP031282_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031282_1

2041681-2041830

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTGTACGGCAGTGAACTC	CRISPRCasFinder
TTTCTAAGCTGCCTGTACGGCAGTGAACTC	PILER-CR

2 spacers

The CRISPR arrays of CP031282_1

>merge|CP031282|1|2041681-2041830|CRISPRCasFinder,PILER-CR
CATTTTATCTGCCTGTACGGCAGTGAACATGGTGGGCGGGTGGAGTATGTTACCAGTGAATTTCTAAGCTGCCTGTACGGCAGTGAACTCGCAAAGGGCTTTTCTGCCATATTCACCATTTTTCTAAGCTGCCTGTACGGCAGTGAACTC

>CP031282|1|1|2041681-2041830|CRISPRCasFinder
CATTTTATCTGCCTGTACGGCAGTGAACAT	GGTGGGCGGGTGGAGTATGTTACCAGTGAA
TTTCTAAGCTGCCTGTACGGCAGTGAACTC	GCAAAGGGCTTTTCTGCCATATTCACCATT
TTTCTAAGCTGCCTGTACGGCAGTGAACTC

>CP031282|1|1|2041689-2041830|PILER-CR
CTGCCTGTACGGCAGTGAACATGGTGGGCG	GGTGGAGTATGTTACCAGTGAATTTCTAAG
CTGCCTGTACGGCAGTGAACTCGCAAAGGG	CTTTTCTGCCATATTCACCATTTTTCTAAG
CTGCCTGTACGGCAGTGAACTC

Protein	Signature genes	Signature genes Name	Protein_function
CP031282.1\|AXM03434.1\|2045231_2045429_-\|hypothetical-protein	unknown	unknown	unknown
CP031282.1\|AXM03441.1\|2067332_2068049_+\|arginine-ABC-transporter-permease-ArtQ	unknown	unknown	gnl\|CDD\|182979
CP031282.1\|AXM03432.1\|2041078_2041297_+\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954
CP031282.1\|AXM03435.1\|2048640_2049591_+\|DUF535-domain-containing-protein	unknown	unknown	gnl\|CDD\|377343
CP031282.1\|AXM03428.1\|2029664_2030276_-\|outer-membrane-lipoprotein-carrier-protein-LolA	unknown	unknown	gnl\|CDD\|129638
CP031282.1\|AXM03437.1\|2063842_2064673_-\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|225567
CP031282.1\|AXM03440.1\|2066594_2067326_+\|arginine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|184969
CP031282.1\|AXM03427.1\|2005885_2007634_-\|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA	unknown	unknown	gnl\|CDD\|183016
CP031282.1\|AXM03442.1\|2068942_2069674_+\|arginine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270418
CP031282.1\|AXM03429.1\|2034451_2034946_-\|leucine-responsive-regulatory-protein	unknown	unknown	gnl\|CDD\|183009
CP031282.1\|AXM04566.1\|2012357_2013041_-\|cytidylate-kinase	unknown	unknown	gnl\|CDD\|234579
CP031282.1\|AXM03436.1\|2051664_2052360_+\|aquaporin	unknown	unknown	gnl\|CDD\|235453
CP031282.1\|AXM03438.1\|2065117_2065633_+\|lipoprotein	unknown	unknown	gnl\|CDD\|182526
CP031282.1\|AXM03430.1\|2035194_2035398_+\|hypothetical-protein	unknown	unknown	unknown
CP031282.1\|AXM03426.1\|2003400_2003583_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|183328
CP031282.1\|AXM03425.1\|2002657_2003404_-\|3-deoxy-manno-octulosonate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|235473
CP031282.1\|AXM03439.1\|2065848_2066577_+\|arginine-ABC-transporter-ATP-binding-protein-ArtP	unknown	unknown	gnl\|CDD\|182980
CP031282.1\|AXM04567.1\|2016667_2018428_+\|30S-ribosomal-protein-S12-methylthiotransferase-accessory-protein-YcaO	unknown	unknown	gnl\|CDD\|132588
CP031282.1\|AXM03433.1\|2044342_2044663_-\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809
CP031282.1\|AXM03431.1\|2036565_2038332_+\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	unknown	unknown	gnl\|CDD\|236870

Protein	Function_ID	Function_description	E-value
CP031282.1\|AXM03432.1\|2041078_2041297_+\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	8.41354e-49
CP031282.1\|AXM03438.1\|2065117_2065633_+\|lipoprotein	gnl\|CDD\|182526	PRK10533, PRK10533, putative lipoprotein; Provisional.	7.78083e-124
CP031282.1\|AXM03428.1\|2029664_2030276_-\|outer-membrane-lipoprotein-carrier-protein-LolA	gnl\|CDD\|129638	TIGR00547, Outer-membrane_lipoprotein_carrier_protein, periplasmic chaperone LolA. This protein, LolA, is known so far only in the gamma and beta subdivisions of the Proteobacteria. The E. coli major outer lipoprotein (Lpp) of E. coli is released from the inner membrane as a complex with this chaperone in an energy-requiring process, and is then delivered to LolB for insertion into the outer membrane. LolA is involved in the delivery of lipoproteins generally, rather than just Lpp, and is an essential protein in E. coli, unlike Lpp itself. [Protein fate, Protein and peptide secretion and trafficking].	1.48786e-125
CP031282.1\|AXM03437.1\|2063842_2064673_-\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|225567	COG3023, ampD, N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane].	2.39069e-108
CP031282.1\|AXM03440.1\|2066594_2067326_+\|arginine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|184969	PRK15007, PRK15007, arginine ABC transporter substrate-binding protein.	1.02618e-176
CP031282.1\|AXM03427.1\|2005885_2007634_-\|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA	gnl\|CDD\|183016	PRK11176, PRK11176, lipid A ABC transporter ATP-binding protein/permease MsbA.	0
CP031282.1\|AXM03442.1\|2068942_2069674_+\|arginine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270418	cd13700, PBP2_Arg_STM4351, Substrate binding domain of arginine-specific ABC transporter; type 2 periplasmic-binding protein fold. This group includes domains similar to Escherichia coli arginine third transport system. STM4351 is the high arginine specific periplasmic-binding protein of ABC transport system. STM4351 belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.64358e-143
CP031282.1\|AXM03429.1\|2034451_2034946_-\|leucine-responsive-regulatory-protein	gnl\|CDD\|183009	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp.	5.32926e-117
CP031282.1\|AXM04566.1\|2012357_2013041_-\|cytidylate-kinase	gnl\|CDD\|234579	PRK00023, cmk, (d)CMP kinase.	2.20176e-133
CP031282.1\|AXM03436.1\|2051664_2052360_+\|aquaporin	gnl\|CDD\|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	2.04944e-144
CP031282.1\|AXM03439.1\|2065848_2066577_+\|arginine-ABC-transporter-ATP-binding-protein-ArtP	gnl\|CDD\|182980	PRK11124, artP, arginine transporter ATP-binding subunit; Provisional.	0
CP031282.1\|AXM03426.1\|2003400_2003583_-\|hypothetical-protein	gnl\|CDD\|183328	PRK11827, PRK11827, protein YcaR.	9.13297e-37
CP031282.1\|AXM03425.1\|2002657_2003404_-\|3-deoxy-manno-octulosonate-cytidylyltransferase	gnl\|CDD\|235473	PRK05450, PRK05450, 3-deoxy-manno-octulosonate cytidylyltransferase; Provisional.	3.48772e-158
CP031282.1\|AXM03441.1\|2067332_2068049_+\|arginine-ABC-transporter-permease-ArtQ	gnl\|CDD\|182979	PRK11123, PRK11123, arginine ABC transporter permease ArtQ.	3.03966e-164
CP031282.1\|AXM04567.1\|2016667_2018428_+\|30S-ribosomal-protein-S12-methylthiotransferase-accessory-protein-YcaO	gnl\|CDD\|132588	TIGR03549, TIGR03549, YcaO domain protein. This family consists of remarkably well-conserved proteins from gamma and beta Proteobacteria, heavily skewed towards organisms of marine environments. Its gene neighborhood is not conserved. This family has an OsmC-like N-terminal domain. It shares a YcaO domain, frequently associated with ATP-dependent cyclodehydration for peptide modification. The function is unknown. Fifteen of the first sixteen members of this family are from selenouridine-positive genomes, but this correlation may not be meaningful.	0
CP031282.1\|AXM03433.1\|2044342_2044663_-\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	5.73364e-49
CP031282.1\|AXM03435.1\|2048640_2049591_+\|DUF535-domain-containing-protein	gnl\|CDD\|377343	pfam04393, DUF535, Protein of unknown function (DUF535). Family member Shigella flexneri VirK is a virulence protein required for the expression, or correct membrane localization of IcsA (VirG) on the bacterial cell surface,. This family also includes Pasteurella haemolytica lapB, which is thought to be membrane-associated.	9.48386e-123
CP031282.1\|AXM03431.1\|2036565_2038332_+\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	gnl\|CDD\|236870	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0

>CP031282.1|AXM03432.1|2041078_2041297_+|translation-initiation-factor-IF-1
MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
>CP031282.1|AXM03431.1|2036565_2038332_+|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD
MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGELNFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELTSTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDTSEQELQTALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGQIIEQGRYAELSVANGPFATLLAHRQEEI
>CP031282.1|AXM03430.1|2035194_2035398_+|hypothetical-protein
MLFFSSSNVFAKQQRIVKAKHRFLVQHARYSLRTVLKHHIVATLIDDLIHMNYEKRNLIDCDYCTNC
>CP031282.1|AXM03429.1|2034451_2034946_-|leucine-responsive-regulatory-protein
MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR
>CP031282.1|AXM03428.1|2029664_2030276_-|outer-membrane-lipoprotein-carrier-protein-LolA
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
>CP031282.1|AXM04567.1|2016667_2018428_+|30S-ribosomal-protein-S12-methylthiotransferase-accessory-protein-YcaO
MTQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNNEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGPDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFIRMYGAEAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKATFWTK
>CP031282.1|AXM04566.1|2012357_2013041_-|cytidylate-kinase
MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDVASEDALVPLASHLDVRFISTNGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQYARQKLALA
>CP031282.1|AXM03427.1|2005885_2007634_-|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA
MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGIALILNAASDTFMLSLLKPLLDDGFGKTDRSVLVWMPLVVIGLMILRGITSYISSYCISWVSGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFAMMFYYSWQLSIILIVLAPIVSIAIRVVSKRFRSISKNMQNTMGQVTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNKMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVMDSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKREIERATGDIEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRFYDIDEGEILMDGHDLREYKLASLRNQVALVSQNVHLFNDTVANNIAYARTEHYSREQIEEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEQADEIVVVEDGVIVERGTHSDLLAHRGVYAQLHKMQFGQ
>CP031282.1|AXM03426.1|2003400_2003583_-|hypothetical-protein
MDHRLLEIIACPVCNGKLWYNQEKQELICKLDKLAFPLRDGIPVLLETEARVLTSEESQS
>CP031282.1|AXM03425.1|2002657_2003404_-|3-deoxy-manno-octulosonate-cytidylyltransferase
MSFVVIIPARFASTRLPGKPLLDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCGFSDDTVIVNVQGDEPMIPAVIIRQVAENLAQRQVGMATLAAPVHSAEEAFNPNVVKVVLDSEGYALYFSRATIPWDRDRFAKGLETVGDNFLRHLGIYGYRAGFIRRYVNWQPSPLEHIEMLEQLRVLWYGEKIHVAVAEQVPGTGVDTAEDLERVRAEMR
>CP031282.1|AXM03433.1|2044342_2044663_-|ATP-dependent-Clp-protease-adapter-ClpS
MSKTNDWLDFDQLAEDKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLTVHYQGKAICGVFTAEVAETKVAMVNNYARENEHPLLCTLEKA
>CP031282.1|AXM03434.1|2045231_2045429_-|hypothetical-protein
MSHVGRGQIYSRKSYTHHTSGCMCCACGFVFHPSRLRQPGSCNANYLEYARTRNKNASRWGWHFV
>CP031282.1|AXM03435.1|2048640_2049591_+|DUF535-domain-containing-protein
MSQLTENTFSPGKSLNSRTLFFRLASGELRPGKFWHRRKFRQKFLLRSLLMPRLSIEWMNELCQMPHINALLVRQPRLPVRLHRPYLTVSFNRQQLLAALRYHYALLRNVMSAEEFNCYLNTPGLQLAQLEGKNGERYTLELTMMISMDKEGDSTILLRNDEGIPLAEITFTLCEYQGKRTLFIGGLQGAKPEIPHQAIQDATKACSGLFPKRLVLEAACRLANRLRVEQILAVSNETHIYRSLRYRDKDEKIHADYNAFWAAVGGECDKQHFYHIPAKIPRKDMAEIASKKRAEYRRRYLLLDTIEEQMSMLFHA
>CP031282.1|AXM03436.1|2051664_2052360_+|aquaporin
MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRD
>CP031282.1|AXM03437.1|2063842_2064673_-|N-acetylmuramoyl-L-alanine-amidase
MRRVFWLVAAALLLAGCAGEKGIVEKEGYQLDTRRQAQAAYPRIKVLVIHYTADDFDSSLATLTDKQVSSHYLVPAVPPRYNGKPRIWQLVPEQELAWHAGISAWRGATRLNDTSIGIELENRGWQKSSGMKYFAPFEPAQIQALIPLAKDIITRYHIKPENVVAHADIAPQRKDDPGPLFPWQQLAQQGIGAWPDAQRVNFYLAGRAPHTPVDSAPLLELLARYGYDVKPDMTPREQRRVIMAFQMHFRPTLYNGEADAETQAIAEALLEKYGQD
>CP031282.1|AXM03438.1|2065117_2065633_+|lipoprotein
MRYSKLTMLIPCALLLSACTTVTPAYKDNGTRTGSCVQGGPDSVAQQFYDYRISHRSNDITALRPYLSDKLATLLSNASRDNSHRELLSSDPFSSRTTLPDSARVASASTIPNRDARNIPLRVDLKQGDQSWQDEVLMIQEGQCWVIDDVRYLGGSVHATAGTLRQSIENR
>CP031282.1|AXM03439.1|2065848_2066577_+|arginine-ABC-transporter-ATP-binding-protein-ArtP
MSIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDFTKTPSDKAIRDLRRNVGMVFQQYNLWPHLTVQQNLIEAPCRVLGLSKDQALARAEKLLERLRLKPFSDRYPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETNITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASCFTEPQTEAFKNYLSH
>CP031282.1|AXM03440.1|2066594_2067326_+|arginine-ABC-transporter-substrate-binding-protein
MKKVLIAALIAGFSLSATAAETIRFATEASYPPFESMDANNQIVGFDVDLAQALCKEIDATCTFSNQAFDSLIPSLKFRRVDAVMAGMDITPEREKQVLFTTPYYDNSALFVGQQGKYTSVDQLKGKKVGVQNGTTHQKFIMDKHPEITTVPYDSYQNAKLDLQNGRIDGVFGDTAVVTEWLKDNPKLAAVGDKVTDKDYFGTGLGIAVRQGNTELQQKFNTALEKVKKDGTYETIYNKWFQK
>CP031282.1|AXM03441.1|2067332_2068049_+|arginine-ABC-transporter-permease-ArtQ
MNEFFPLASAAGMTVGLAVCALIVGLALAMFFAVWESAKWRPVAWAGSALVTILRGLPEILVVLFIYFGSSQLLLTLSDGFTINLGIVQIPVQMDIENFDVSPFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALPGLGNQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIVAAAIYLVITLLSQYILKRIDLRATRFERRPS
>CP031282.1|AXM03442.1|2068942_2069674_+|arginine-ABC-transporter-substrate-binding-protein
MKKLVLAALLASCAFGASAAEKINFGVSATYPPFESIGANNEIVGFDIDLAKALCKQMQAECTFTNHAFDSLIPSLKFKKYDAVISGMDITPERSKQVSFTTPYYENSAVVIAKKDTYKTFADLKGKRIGMENGTTHQKYIQDQHPEVKTVSYDSYQNAFIDLKNGRIDGVFGDTAVVNEWLKTNPQLGVATEKVTDPQYFGTGLGIAVRPDNKALLEKLNNALAAIKADGTYKKINDQWFPQ

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Crispr_ID: CP031282_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031282_2

2694310-2694759

TypeI-E

I-E

Consensus_repeat	Method
TCGGTTTATCCCCGCTGGCGCGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGAACAC	CRT
CGGTTTATCCCCGCTGGCGCGGG	PILER-CR

7 spacers

cas2,cas1,cse2gr11

The CRISPR arrays of CP031282_2

>merge|CP031282|2|2694310-2694759|CRISPRCasFinder,CRT,PILER-CR
GCTGGGAGTTCCCGCTGGCGCGGGAACACAATATCTGTTGTAACCGTGGTGAGTGCATTACCGGTTTATCCCCGCTGGCGCGGGAACACCGCGGCACTGACACGAAACAATCAGCAGGTGGCGGTTTATCCCGCTGGCGCGGGAACACATTGAATGGAACCGTACGTAACGCAGGAATGCCGGTTTATCCCCGCTGGCGCGGGGAACACACGACCAGTGCCACCAGAATTAATAATTTTTTCGGTTTATCCCCGCTGGCGCGGGAACACACCGATCGCTTGAATGATTGATAATTCGCGCTCGGTTTATCCCCGCTGGCGCGGGAACACTGTTCCAGGTCCTCCGGATCAACCTGAAATTTCGGTTTATCCCCGCTGGCGCGGGGAACACGACGCGCGGCACGATTAAACCAAAATGGCCGACGGTTTATCCCCGCTGGCGCGGGAACAC

>CP031282|2|2|2694310-2694759|CRISPRCasFinder
GCTGGGAGTTCCCGCTGGCGCGGGAACAC	AATATCTGTTGTAACCGTGGTGAGTGCATTA
CCGGTTTATCCCCGCTGGCGCGGGAACAC	CGCGGCACTGACACGAAACAATCAGCAGGT
GGCGGTTTATCCCGCTGGCGCGGGAACAC	ATTGAATGGAACCGTACGTAACGCAGGAATG
CCGGTTTATCCCCGCTGGCGCGGGGAACA	CACGACCAGTGCCACCAGAATTAATAATTTTT
TCGGTTTATCCCCGCTGGCGCGGGAACAC	ACCGATCGCTTGAATGATTGATAATTCGCGC
TCGGTTTATCCCCGCTGGCGCGGGAACAC	TGTTCCAGGTCCTCCGGATCAACCTGAAATT
TCGGTTTATCCCCGCTGGCGCGGGGAACA	CGACGCGCGGCACGATTAAACCAAAATGGCCG
ACGGTTTATCCCCGCTGGCGCGGGAACAC

>CP031282|2|1|2694311-2694759|CRT
CTGGGAGTTCCCGCTGGCGCGGGAACAC	AATATCTGTTGTAACCGTGGTGAGTGCATTAC
CGGTTTATCCCCGCTGGCGCGGGAACAC	CGCGGCACTGACACGAAACAATCAGCAGGTG
GCGGTTTATCCCGCTGGCGCGGGAACAC	ATTGAATGGAACCGTACGTAACGCAGGAATGC
CGGTTTATCCCCGCTGGCGCGGGGAACA	CACGACCAGTGCCACCAGAATTAATAATTTTTT
CGGTTTATCCCCGCTGGCGCGGGAACAC	ACCGATCGCTTGAATGATTGATAATTCGCGCT
CGGTTTATCCCCGCTGGCGCGGGAACAC	TGTTCCAGGTCCTCCGGATCAACCTGAAATTT
CGGTTTATCCCCGCTGGCGCGGGGAACA	CGACGCGCGGCACGATTAAACCAAAATGGCCGA
CGGTTTATCCCCGCTGGCGCGGGAACAC

>CP031282|2|2|2694371-2694754|PILER-CR
CGGTTTATCCCCGCTGGCGCGGG	AACACCGCGGCACTGACACGAAACAATCAGCAGGTGGCGGTTTAT
CCCGCTGGCGCGGGAACACATTG	AATGGAACCGTACGTAACGCAGGAATGCCGGTTTATC
CCCGCTGGCGCGGGGAACACACG	ACCAGTGCCACCAGAATTAATAATTTTTTCGGTTTATC
CCCGCTGGCGCGGGAACACACCG	ATCGCTTGAATGATTGATAATTCGCGCTCGGTTTATC
CCCGCTGGCGCGGGAACACTGTT	CCAGGTCCTCCGGATCAACCTGAAATTTCGGTTTATC
CCCGCTGGCGCGGGGAACACGAC	GCGCGGCACGATTAAACCAAAATGGCCGACGGTTTATC
CCCGCTGGCGCGGG

Protein	Signature genes	Signature genes Name	Protein_function
CP031282.1\|AXM03669.1\|2689688_2690012_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
CP031282.1\|AXM04590.1\|2704035_2704770_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
CP031282.1\|AXM03678.1\|2708669_2709035_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
CP031282.1\|AXM03672.1\|2692095_2693004_-\|sulfate-adenylyltransferase-subunit-2	unknown	unknown	gnl\|CDD\|235375
CP031282.1\|AXM03674.1\|2695048_2696068_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
CP031282.1\|AXM03665.1\|2685590_2686217_-\|protein-L-isoaspartate-O-methyltransferase	unknown	unknown	gnl\|CDD\|178974
CP031282.1\|AXM03679.1\|2709395_2709659_-\|hypothetical-protein	unknown	unknown	unknown
CP031282.1\|AXM03680.1\|2711783_2712131_-\|transposase	unknown	unknown	gnl\|CDD\|377551
CP031282.1\|AXM03667.1\|2689202_2689514_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
CP031282.1\|AXM03673.1\|2694855_2695149_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
CP031282.1\|AXM03664.1\|2682726_2683134_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
CP031282.1\|AXM03663.1\|2681986_2682580_-\|UbiX-family-flavin-prenyltransferase	unknown	unknown	gnl\|CDD\|223241
CP031282.1\|AXM03671.1\|2690666_2692094_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
CP031282.1\|AXM03670.1\|2690061_2690667_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
CP031282.1\|AXM03677.1\|2706554_2708354_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
CP031282.1\|AXM03681.1\|2712296_2712509_-\|transposase	unknown	unknown	gnl\|CDD\|225511
CP031282.1\|AXM03675.1\|2698540_2699077_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
CP031282.1\|AXM03676.1\|2703616_2703769_-\|type-I-toxin-antitoxin-system-hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
CP031282.1\|AXM03666.1\|2686951_2688001_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
CP031282.1\|AXM03668.1\|2689501_2689687_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP031282.1\|AXM03669.1\|2689688_2690012_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	5.35907e-46
CP031282.1\|AXM04590.1\|2704035_2704770_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.49443e-136
CP031282.1\|AXM03678.1\|2708669_2709035_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	9.8593e-60
CP031282.1\|AXM03672.1\|2692095_2693004_-\|sulfate-adenylyltransferase-subunit-2	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
CP031282.1\|AXM03674.1\|2695048_2696068_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.84789e-156
CP031282.1\|AXM03665.1\|2685590_2686217_-\|protein-L-isoaspartate-O-methyltransferase	gnl\|CDD\|178974	PRK00312, pcm, protein-L-isoaspartate(D-aspartate) O-methyltransferase.	5.71208e-125
CP031282.1\|AXM03680.1\|2711783_2712131_-\|transposase	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	5.69907e-48
CP031282.1\|AXM03667.1\|2689202_2689514_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	1.1114e-62
CP031282.1\|AXM03673.1\|2694855_2695149_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	3.0872e-65
CP031282.1\|AXM03664.1\|2682726_2683134_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	7.53687e-18
CP031282.1\|AXM03663.1\|2681986_2682580_-\|UbiX-family-flavin-prenyltransferase	gnl\|CDD\|223241	COG0163, UbiX family flavin prenyltransferase [Coenzyme transport and metabolism].	8.68243e-111
CP031282.1\|AXM03671.1\|2690666_2692094_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
CP031282.1\|AXM03670.1\|2690061_2690667_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	2.0819e-148
CP031282.1\|AXM03677.1\|2706554_2708354_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
CP031282.1\|AXM03681.1\|2712296_2712509_-\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.06944e-10
CP031282.1\|AXM03675.1\|2698540_2699077_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	4.26268e-28
CP031282.1\|AXM03676.1\|2703616_2703769_-\|type-I-toxin-antitoxin-system-hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
CP031282.1\|AXM03666.1\|2686951_2688001_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0

>CP031282.1|AXM03672.1|2692095_2693004_-|sulfate-adenylyltransferase-subunit-2
MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>CP031282.1|AXM03671.1|2690666_2692094_-|sulfate-adenylyltransferase-subunit-CysN
MNTVLAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLIVAINKMDLVDYSEETFTRIREDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSESMSWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNIARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSTFELELNALVRRHFPHWGARDLLGDK
>CP031282.1|AXM03670.1|2690061_2690667_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQREQHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERLGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEINLNGEQLVTNLVQQLLDLLRQNDIIRS
>CP031282.1|AXM03669.1|2689688_2690012_-|DUF3561-family-protein
MRNSDNITFTKSEAFAVDDETTWSLSGAAVGFVSWLFALAIPFLVYGPNTLFFFLYTWPFFLALMPVAVVAGIALHSLTGGKLLYTILLTLLIVGVMFGALFLWLLG
>CP031282.1|AXM03668.1|2689501_2689687_-|hypothetical-protein
MPIIQTVTNNEIMFRTPWVYVTMDKCGTFARVVAAFQPQCIAFVGQIWDENAVFQGAGWVN
>CP031282.1|AXM03667.1|2689202_2689514_-|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYSRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTKPGETFYRLVPDASKRAQTAGQNNR
>CP031282.1|AXM03666.1|2686951_2688001_-|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWFCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLRDVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAEETELQTLLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGEYAHIAE
>CP031282.1|AXM03665.1|2685590_2686217_-|protein-L-isoaspartate-O-methyltransferase
MVSRRVQVLLDQLRAQGIKDEQVLNALAAVPREKFIDEAFEQKAWDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCSVERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMTQLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA
>CP031282.1|AXM03664.1|2682726_2683134_+|MarR-family-transcriptional-regulator
MALRNKAFHQLRQLFQQHTSRWQHELPDLTKPQYAVMRAIADKPGIEQVALMEAAVSTKATLAEMLARMENRGLVRREHDSADKRRRFVWLTAEGEKVLAAAIPIGDSVDEEFLGRLSGEEQELFMQLVRKMMSK
>CP031282.1|AXM03663.1|2681986_2682580_-|UbiX-family-flavin-prenyltransferase
MRLIVGMTGATGAPLGVALLQALREMPNVETHLVMSKWAKTTIELETPYNARDVAALADFCHNPADQAATISSGSFRTDGMIVIPCSMKTLAGIRAGYADGLVGRAADVVLKEGRKLVLVPREMPLSTIHLENMLALSRMGVAMVPPMPAFYNHPETVDDIVHHVVARVLDQFGLEHPHARRWQGLPQARNFSQENE
>CP031282.1|AXM03673.1|2694855_2695149_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQISQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>CP031282.1|AXM03674.1|2695048_2696068_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSIVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAADMLPPAIPEPETLGDIGHRGAAGEHGRGCYRKCPAALTWTARNLAPGSACRCVCW
>CP031282.1|AXM03675.1|2698540_2699077_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWHEELQEKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKVEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSEGRFSRLSAVKTPDDLLRQLRRAVKLLNGSVNLISLADDIFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQN
>CP031282.1|AXM03676.1|2703616_2703769_-|type-I-toxin-antitoxin-system-hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>CP031282.1|AXM04590.1|2704035_2704770_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVLLTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>CP031282.1|AXM03677.1|2706554_2708354_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALTATPAPAAEMPGITIISASQTGNARRVAETLRDDLLAAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKSKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGAGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
>CP031282.1|AXM03678.1|2708669_2709035_+|6-carboxytetrahydropterin-synthase-QueD
MMSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRGE
>CP031282.1|AXM03679.1|2709395_2709659_-|hypothetical-protein
MSTLMEKECLLNGVSQNIAFLSKLSEMVYNSQNEELQHEIYELVSYKDYLYSTGHELVDFQEGVLRFQKIRIKYRQELKELGYPVGN
>CP031282.1|AXM03680.1|2711783_2712131_-|transposase
MINLPAGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFIFRGRSGSQVKLLWSTGDGLCPLTKRLERGRFARSSARDGKVFLTPAQLAMLMEGIDWRQPKRLLTSLTML
>CP031282.1|AXM03681.1|2712296_2712509_-|transposase
MRAKERFPRKHYSPEFKMELVRLALEEEGSIAALARKHDVNDNLLFKWIRLWQREGGSVGPEKTHRRFLP

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Crispr_ID: CP031282_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031282_3

2709785-2710167

TypeI-E

I-E:NA

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGAACTC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCG	CRT
GTTTATCCCCGCTGGCGCGGGGAACTC	PILER-CR

6 spacers

cse2gr11,cas1,cas2

The CRISPR arrays of CP031282_3

>merge|CP031282|3|2709785-2710167|CRISPRCasFinder,CRT,PILER-CR
CGGTTTATCCTCACTGGCGCGGGGAACTCTTGAGACATCGCAACGTTAACAATCTCGCCAACGGTTTATCCCCGCTGGCGTGGGGAACTCGTCGGGATTAACCGCTCGTGTGCCGTCGTCGTCAGTTTATCCCCGCTGGCGCGGGGAACTCACGCACCGTGTTAAACCGGCAGAAAAACAGCACGGTTTATCCCCGCTGGCGCGGGAACTCTCTCCGATGCCCGTAATGCGTTCGGACAGTTCCGGTTTATCCCCGCTGGCGCGGGGAACTCATCAAACAATGCTGAATCCCAGGTTGTGTCATCGGTTTATCCCCGCTGGCGCGGGAACTCGGCTTCTCAACGAAGGCATCGATTATCGGCTGCGGTTTATCCCCGTAAGCG

>CP031282|3|3|2709785-2710116|CRISPRCasFinder
CGGTTTATCCTCACTGGCGCGGGGAACT	CTTGAGACATCGCAACGTTAACAATCTCGCCAA
CGGTTTATCCCCGCTGGCGTGGGGAACT	CGTCGGGATTAACCGCTCGTGTGCCGTCGTCGT
CAGTTTATCCCCGCTGGCGCGGGGAACT	CACGCACCGTGTTAAACCGGCAGAAAAACAGCA
CGGTTTATCCCCGCTGGCGCGGGAACTC	TCTCCGATGCCCGTAATGCGTTCGGACAGTTC
CGGTTTATCCCCGCTGGCGCGGGGAACT	CATCAAACAATGCTGAATCCCAGGTTGTGTCAT
CGGTTTATCCCCGCTGGCGCGGGAACTC

>CP031282|3|2|2709785-2710167|CRT
CGGTTTATCCTCACTGGCG	CGGGGAACTCTTGAGACATCGCAACGTTAACAATCTCGCCAA
CGGTTTATCCCCGCTGGCG	TGGGGAACTCGTCGGGATTAACCGCTCGTGTGCCGTCGTCGT
CAGTTTATCCCCGCTGGCG	CGGGGAACTCACGCACCGTGTTAAACCGGCAGAAAAACAGCA
CGGTTTATCCCCGCTGGCG	CGGGAACTCTCTCCGATGCCCGTAATGCGTTCGGACAGTTC
CGGTTTATCCCCGCTGGCG	CGGGGAACTCATCAAACAATGCTGAATCCCAGGTTGTGTCAT
CGGTTTATCCCCGCTGGCG	CGGGAACTCGGCTTCTCAACGAAGGCATCGATTATCGGCTG
CGGTTTATCCCCGTAAGCG

>CP031282|3|3|2709848-2710056|PILER-CR
GTTTATCCCCGCTGGCGTGGGGAACTC	GTCGGGATTAACCGCTCGTGTGCCGTCGTCGTCA
GTTTATCCCCGCTGGCGCGGGGAACTC	ACGCACCGTGTTAAACCGGCAGAAAAACAGCACG
GTTTATCCCCGCTGGCGCGGGAACTCT	CTCCGATGCCCGTAATGCGTTCGGACAGTTCCGGTTTAT
CCCCGCTGGCGCGGGGAACTC

Protein	Signature genes	Signature genes Name	Protein_function
CP031282.1\|AXM03683.1\|2725597_2728354_+\|two-component-sensor-histidine-kinase-BarA	unknown	unknown	gnl\|CDD\|236848
CP031282.1\|AXM04592.1\|2741960_2743250_+\|HAAAP-family-serine/threonine-permease	unknown	unknown	gnl\|CDD\|273283
CP031282.1\|AXM04590.1\|2704035_2704770_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
CP031282.1\|AXM03672.1\|2692095_2693004_-\|sulfate-adenylyltransferase-subunit-2	unknown	unknown	gnl\|CDD\|235375
CP031282.1\|AXM03687.1\|2744786_2745542_+\|flap-endonuclease-Xni	unknown	unknown	gnl\|CDD\|181896
CP031282.1\|AXM04591.1\|2737512_2737842_-\|YqcC-family-protein	unknown	unknown	gnl\|CDD\|225640
CP031282.1\|AXM03682.1\|2717827_2719126_-\|enolase	unknown	unknown	gnl\|CDD\|234617
CP031282.1\|AXM03674.1\|2695048_2696068_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
CP031282.1\|AXM03678.1\|2708669_2709035_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
CP031282.1\|AXM03679.1\|2709395_2709659_-\|hypothetical-protein	unknown	unknown	unknown
CP031282.1\|AXM03676.1\|2703616_2703769_-\|type-I-toxin-antitoxin-system-hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
CP031282.1\|AXM03685.1\|2736730_2737513_-\|tRNA-pseudouridine(65)-synthase-TruC	unknown	unknown	gnl\|CDD\|182971
CP031282.1\|AXM03673.1\|2694855_2695149_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
CP031282.1\|AXM03686.1\|2743307_2744675_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|273233
CP031282.1\|AXM03671.1\|2690666_2692094_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
CP031282.1\|AXM03677.1\|2706554_2708354_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
CP031282.1\|AXM03675.1\|2698540_2699077_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
CP031282.1\|AXM03680.1\|2711783_2712131_-\|transposase	unknown	unknown	gnl\|CDD\|377551
CP031282.1\|AXM03681.1\|2712296_2712509_-\|transposase	unknown	unknown	gnl\|CDD\|225511
CP031282.1\|AXM03684.1\|2733387_2733651_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275016

Protein	Function_ID	Function_description	E-value
CP031282.1\|AXM03683.1\|2725597_2728354_+\|two-component-sensor-histidine-kinase-BarA	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	0
CP031282.1\|AXM04592.1\|2741960_2743250_+\|HAAAP-family-serine/threonine-permease	gnl\|CDD\|273283	TIGR00814, membrane_transport_protein_YhjV, serine transporter. The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family- serine/threonine subfamily (TC 2.A.42.2) The HAAAP family includes well characterized aromatic amino acid:H+ symport permeases and hydroxy amino acid permeases. This subfamily is specific for hydroxy amino acid transporters and includes the serine permease, SdaC, of E. coli, and the threonine permease, TdcC, of E. coli.//added GO terms, none avaialbelf or ser/thr specifically [SS 2/6/05] [Transport and binding proteins, Amino acids, peptides and amines].	0
CP031282.1\|AXM04590.1\|2704035_2704770_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.49443e-136
CP031282.1\|AXM03672.1\|2692095_2693004_-\|sulfate-adenylyltransferase-subunit-2	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
CP031282.1\|AXM03687.1\|2744786_2745542_+\|flap-endonuclease-Xni	gnl\|CDD\|181896	PRK09482, PRK09482, flap endonuclease-like protein; Provisional.	1.44833e-177
CP031282.1\|AXM04591.1\|2737512_2737842_-\|YqcC-family-protein	gnl\|CDD\|225640	COG3098, COG3098, Uncharacterized protein conserved in bacteria [Function unknown].	5.35412e-45
CP031282.1\|AXM03682.1\|2717827_2719126_-\|enolase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
CP031282.1\|AXM03674.1\|2695048_2696068_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.84789e-156
CP031282.1\|AXM03678.1\|2708669_2709035_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	9.8593e-60
CP031282.1\|AXM03676.1\|2703616_2703769_-\|type-I-toxin-antitoxin-system-hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
CP031282.1\|AXM03685.1\|2736730_2737513_-\|tRNA-pseudouridine(65)-synthase-TruC	gnl\|CDD\|182971	PRK11112, PRK11112, tRNA pseudouridine synthase C; Provisional.	0
CP031282.1\|AXM03673.1\|2694855_2695149_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	3.0872e-65
CP031282.1\|AXM03686.1\|2743307_2744675_+\|L-serine-ammonia-lyase	gnl\|CDD\|273233	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form. This enzyme is also called serine deaminase and L-serine dehydratase 1. L-serine ammonia-lyase converts serine into pyruvate in the gluconeogenesis pathway from serine. This enzyme is comprised of a single chain in Escherichia coli, Mycobacterium tuberculosis, and several other species, but has separate alpha and beta chains in Bacillus subtilis and related species. The beta and alpha chains are homologous to the N-terminal and C-terminal regions, respectively, but are rather deeply branched in a UPGMA tree. This enzyme requires iron and dithiothreitol for activation in vitro, and is a predicted 4Fe-4S protein. Escherichia coli Pseudomonas aeruginosa have two copies of this protein. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	0
CP031282.1\|AXM03671.1\|2690666_2692094_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
CP031282.1\|AXM03677.1\|2706554_2708354_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
CP031282.1\|AXM03675.1\|2698540_2699077_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	4.26268e-28
CP031282.1\|AXM03680.1\|2711783_2712131_-\|transposase	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	5.69907e-48
CP031282.1\|AXM03681.1\|2712296_2712509_-\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.06944e-10
CP031282.1\|AXM03684.1\|2733387_2733651_+\|hypothetical-protein	gnl\|CDD\|275016	TIGR04154, archaeo_STT3, oligosaccharyl transferase, archaeosortase A system-associated. Members of this protein family occur, one to three members per genome, in the same species of Euryarchaeota as contain the predicted protein-sorting enzyme archaeosortase (TIGR04125) and its cognate protein-sorting signal PGF-CTERM (TIGR04126).	0.00597662

>CP031282.1|AXM03679.1|2709395_2709659_-|hypothetical-protein
MSTLMEKECLLNGVSQNIAFLSKLSEMVYNSQNEELQHEIYELVSYKDYLYSTGHELVDFQEGVLRFQKIRIKYRQELKELGYPVGN
>CP031282.1|AXM03678.1|2708669_2709035_+|6-carboxytetrahydropterin-synthase-QueD
MMSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRGE
>CP031282.1|AXM03677.1|2706554_2708354_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALTATPAPAAEMPGITIISASQTGNARRVAETLRDDLLAAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKSKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGAGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
>CP031282.1|AXM04590.1|2704035_2704770_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVLLTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>CP031282.1|AXM03676.1|2703616_2703769_-|type-I-toxin-antitoxin-system-hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>CP031282.1|AXM03675.1|2698540_2699077_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWHEELQEKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKVEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSEGRFSRLSAVKTPDDLLRQLRRAVKLLNGSVNLISLADDIFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQN
>CP031282.1|AXM03674.1|2695048_2696068_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSIVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAADMLPPAIPEPETLGDIGHRGAAGEHGRGCYRKCPAALTWTARNLAPGSACRCVCW
>CP031282.1|AXM03673.1|2694855_2695149_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQISQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>CP031282.1|AXM03672.1|2692095_2693004_-|sulfate-adenylyltransferase-subunit-2
MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>CP031282.1|AXM03671.1|2690666_2692094_-|sulfate-adenylyltransferase-subunit-CysN
MNTVLAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLIVAINKMDLVDYSEETFTRIREDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSESMSWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNIARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSTFELELNALVRRHFPHWGARDLLGDK
>CP031282.1|AXM03680.1|2711783_2712131_-|transposase
MINLPAGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFIFRGRSGSQVKLLWSTGDGLCPLTKRLERGRFARSSARDGKVFLTPAQLAMLMEGIDWRQPKRLLTSLTML
>CP031282.1|AXM03681.1|2712296_2712509_-|transposase
MRAKERFPRKHYSPEFKMELVRLALEEEGSIAALARKHDVNDNLLFKWIRLWQREGGSVGPEKTHRRFLP
>CP031282.1|AXM03682.1|2717827_2719126_-|enolase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>CP031282.1|AXM03683.1|2725597_2728354_+|two-component-sensor-histidine-kinase-BarA
MTNYSLRARMMILILAPTVLIGLLLSLFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMNLQNRESIGQLISVLHRRHSDIVRAISVFDENNHLFVTSNFHLDPSAMQLSSGAPFPRQLSVTRNGDVMILRTPIISESYSPDESPSSEAKNSQNMLGYVALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLTIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKGDVPDNVIGDPLRLQQIITNLVGNAIKFTERGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVIYSPTFSALPESHYDIMLLGIAVTFREPLTLHHERLDKAVAMTDFLLLALPCHAQVNAEKLKQEGVGACLLKPLTSTRLLPALKEFGNKNQIHSLSSTDENKLAMTVMAVDDNPANLKLIGALLEDKVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPDVNEVMVNQNTTLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENTDGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPEFLELLDEMDNVAREAKKILG
>CP031282.1|AXM03684.1|2733387_2733651_+|hypothetical-protein
MVKSFLSTPVINCCFNLLLYLFPGIFGFVISCAIYIFLQTLVLLPRKKKRNYPLFAVVAFVVSSSIFFLFRFGFDILLPAGVMGALL
>CP031282.1|AXM03685.1|2736730_2737513_-|tRNA-pseudouridine(65)-synthase-TruC
MLEILYQDEWLVAVNKPSGWLVHRSWLDRDEKVVVMQTVRDQIGQHVFTAHRLDRPTSGVLLMGLSSEAGRLLAQQFEQHQIQKRYHAIVRGWLMEEAVLDYPLVEELDKIADKYAREDKGPQPAVTQYRGLATVEMPVATGRYPTTRYGLVELEPKTGRKHQLRRHLAHLRHPIIGDSKHGDLRQNRSGAEHFGLQRLMLHASQLSLTHPFTGELLTIHAGLDDIWMQALSQFGWRGLLPENERVEFSGPAVQDEEISS
>CP031282.1|AXM04591.1|2737512_2737842_-|YqcC-family-protein
MMTHEQVRQQLLVLESLLREHQFWQTEAPQAHQFTSTQPFFMDTMEPLEWLQWVLIPRMHALLDSHQPLPDAFAVAPYYEMALENDHPQRELLLAELQKLDALFADDAN
>CP031282.1|AXM04592.1|2741960_2743250_+|HAAAP-family-serine/threonine-permease
METTQTSTIVSKDSRSAWRKTDTMWMLGLYGTAIGAGVLFLPINAGVGGMIPLIIMAILAFPMTFFAHRGLTRFVLSGKNPGEDITEVVEEHFGIGAGKLITLLYFFAIYPILLVYSVAITNTVESFMTHQLGMTPPPRAILSLILIVGMMTIVRFGEQMIVKAMSILVFPFVGVLMLLALYLIPQWNGAALETLSLDTASATGNGLWMTLWLAIPVMVFSFNHSPIISSFAVAKREEYGDMAEKKCSKILAFAHIMMVLTVMFFVFSCVLSLSPADLAAAKEQNISILSYLANHFNAPIIAWMAPIIAIIAITKSFLGHYLGAREGFNGMVIKSLRGKGKSIEINKLNRITALFMLVTTWIVATLNPSILGMIETLGGPIIAMILFLMPMYAIQKVPAMRKYSGHISNVFVVVMGLIAISAIFYSLFS
>CP031282.1|AXM03686.1|2743307_2744675_+|L-serine-ammonia-lyase
MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARNLLKDVTRVVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDIDSIPGFIQDVNTHGRLMVANGQHEVEFPVDQCMNFHADNLSLHENGMRITALAGDKVVYSQTYYSIGGGFIVDEEHFGQQDSAPVEVPYPYSSAADLQKHCQETGLSLSGLMMKNELALHSKEELEQHLANVWEVMRGGIERGISTEGVLPGKLRVPRRAAALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENAAGGRVVTAPTNGACGIIPAVLAYYDKFIREVNANSLARYLLVASAIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGASPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPCIERNAIAAVKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMKIVACD
>CP031282.1|AXM03687.1|2744786_2745542_+|flap-endonuclease-Xni
MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHVVAVFDDENRNSGWRHQRLPDYKAGRPPMPDELHNEMPTLRAAFEQRGVPCWSATGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLEMHKEMAFLCRDIARLQTDVHIDGNLQQLRLKR

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Crispr_ID: CP031282_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031282_4

2712587-2713034

TypeI-E

I-E:NA

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGAACTC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGG	CRT
GTTTATCCCCGCTGGCGCGGG	PILER-CR

7 spacers

cse2gr11,cas1,cas2

The CRISPR arrays of CP031282_4

>merge|CP031282|4|2712587-2713034|CRISPRCasFinder,CRT,PILER-CR
GCTTACATCCCCGCTGGCGCGGGAACTCATCCGCGAGATCAACAGTGGTTGCGAGATCGACGGTTTATCCCCGCTGGCGCGGGGAACTCTCAACCACCACCGCCACTACTGTATTTTTCGCCGGTTTATCCCCGCTGGCGCGGGAACTCATGAGGAGGATTATTTCAAACCGGCGATAACGCGGTTTATCCCCGCTGGCGCGGGAACTCCGCCGAGCCAGACAAATAAGATACTCACAAAACGGTTTATCCCCGCTGGCGCGGGGAACTCGAATCTGTTAATTCCGTGAGTTAAAAGAGTTCGGTTTATCCCGCTGGCGCGGGAACTCATCCAGGCGCTCAATTACCGCCGCACCAAGATCGGTTTATCCCCGCTGGCGCGGGAACTCCGCGGGCATGGCAACGCTGCGGGCGTGCGAATCGGTTTATCCCCGCTGGCGCGGGGAACT

>CP031282|4|4|2712587-2713034|CRISPRCasFinder
GCTTACATCCCCGCTGGCGCGGGAACTC	ATCCGCGAGATCAACAGTGGTTGCGAGATCGA
CGGTTTATCCCCGCTGGCGCGGGGAACT	CTCAACCACCACCGCCACTACTGTATTTTTCGC
CGGTTTATCCCCGCTGGCGCGGGAACTC	ATGAGGAGGATTATTTCAAACCGGCGATAACG
CGGTTTATCCCCGCTGGCGCGGGAACTC	CGCCGAGCCAGACAAATAAGATACTCACAAAA
CGGTTTATCCCCGCTGGCGCGGGGAACT	CGAATCTGTTAATTCCGTGAGTTAAAAGAGT
TCGGTTTATCCCGCTGGCGCGGGAACTC	ATCCAGGCGCTCAATTACCGCCGCACCAAGAT
CGGTTTATCCCCGCTGGCGCGGGAACTC	CGCGGGCATGGCAACGCTGCGGGCGTGCGAAT
CGGTTTATCCCCGCTGGCGCGGGGAACT

>CP031282|4|3|2712587-2713029|CRT
GCTTACATCCCCGCTGGCGCGGG	AACTCATCCGCGAGATCAACAGTGGTTGCGAGATCGA
CGGTTTATCCCCGCTGGCGCGGG	GAACTCTCAACCACCACCGCCACTACTGTATTTTTCGC
CGGTTTATCCCCGCTGGCGCGGG	AACTCATGAGGAGGATTATTTCAAACCGGCGATAACG
CGGTTTATCCCCGCTGGCGCGGG	AACTCCGCCGAGCCAGACAAATAAGATACTCACAAAA
CGGTTTATCCCCGCTGGCGCGGG	GAACTCGAATCTGTTAATTCCGTGAGTTAAAAGAGT
TCGGTTTATCCCGCTGGCGCGGG	AACTCATCCAGGCGCTCAATTACCGCCGCACCAAGAT
CGGTTTATCCCCGCTGGCGCGGG	AACTCCGCGGGCATGGCAACGCTGCGGGCGTGCGAAT
CGGTTTATCCCCGCTGGCGCGGG

>CP031282|4|4|2712649-2713029|PILER-CR
GTTTATCCCCGCTGGCGCGGG	GAACTCTCAACCACCACCGCCACTACTGTATTTTTCGCCG
GTTTATCCCCGCTGGCGCGGG	AACTCATGAGGAGGATTATTTCAAACCGGCGATAACGCG
GTTTATCCCCGCTGGCGCGGG	AACTCCGCCGAGCCAGACAAATAAGATACTCACAAAACG
GTTTATCCCCGCTGGCGCGGG	GAACTCGAATCTGTTAATTCCGTGAGTTAAAAGAGTTCGGTTTAT
CCCGCTGGCGCGGGAACTCAT	CCAGGCGCTCAATTACCGCCGCACCAAGATCGGTTTATC
CCCGCTGGCGCGGGAACTCCG	CGGGCATGGCAACGCTGCGGGCGTGCGAATCGGTTTATC
CCCGCTGGCGCGGG

Protein	Signature genes	Signature genes Name	Protein_function
CP031282.1\|AXM03683.1\|2725597_2728354_+\|two-component-sensor-histidine-kinase-BarA	unknown	unknown	gnl\|CDD\|236848
CP031282.1\|AXM04592.1\|2741960_2743250_+\|HAAAP-family-serine/threonine-permease	unknown	unknown	gnl\|CDD\|273283
CP031282.1\|AXM04590.1\|2704035_2704770_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
CP031282.1\|AXM03687.1\|2744786_2745542_+\|flap-endonuclease-Xni	unknown	unknown	gnl\|CDD\|181896
CP031282.1\|AXM03689.1\|2746688_2747084_-\|DUF423-domain-containing-protein	unknown	unknown	gnl\|CDD\|182798
CP031282.1\|AXM04591.1\|2737512_2737842_-\|YqcC-family-protein	unknown	unknown	gnl\|CDD\|225640
CP031282.1\|AXM03686.1\|2743307_2744675_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|273233
CP031282.1\|AXM03681.1\|2712296_2712509_-\|transposase	unknown	unknown	gnl\|CDD\|225511
CP031282.1\|AXM03678.1\|2708669_2709035_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
CP031282.1\|AXM03679.1\|2709395_2709659_-\|hypothetical-protein	unknown	unknown	unknown
CP031282.1\|AXM03682.1\|2717827_2719126_-\|enolase	unknown	unknown	gnl\|CDD\|234617
CP031282.1\|AXM03676.1\|2703616_2703769_-\|type-I-toxin-antitoxin-system-hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
CP031282.1\|AXM03673.1\|2694855_2695149_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
CP031282.1\|AXM03688.1\|2745595_2746696_-\|23S-rRNA-(cytidine(2498)-2'-O)-methyltransferase-RlmM	unknown	unknown	gnl\|CDD\|236971
CP031282.1\|AXM03684.1\|2733387_2733651_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275016
CP031282.1\|AXM03677.1\|2706554_2708354_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
CP031282.1\|AXM03675.1\|2698540_2699077_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
CP031282.1\|AXM03685.1\|2736730_2737513_-\|tRNA-pseudouridine(65)-synthase-TruC	unknown	unknown	gnl\|CDD\|182971
CP031282.1\|AXM03680.1\|2711783_2712131_-\|transposase	unknown	unknown	gnl\|CDD\|377551
CP031282.1\|AXM03674.1\|2695048_2696068_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693

Protein	Function_ID	Function_description	E-value
CP031282.1\|AXM03683.1\|2725597_2728354_+\|two-component-sensor-histidine-kinase-BarA	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	0
CP031282.1\|AXM04592.1\|2741960_2743250_+\|HAAAP-family-serine/threonine-permease	gnl\|CDD\|273283	TIGR00814, membrane_transport_protein_YhjV, serine transporter. The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family- serine/threonine subfamily (TC 2.A.42.2) The HAAAP family includes well characterized aromatic amino acid:H+ symport permeases and hydroxy amino acid permeases. This subfamily is specific for hydroxy amino acid transporters and includes the serine permease, SdaC, of E. coli, and the threonine permease, TdcC, of E. coli.//added GO terms, none avaialbelf or ser/thr specifically [SS 2/6/05] [Transport and binding proteins, Amino acids, peptides and amines].	0
CP031282.1\|AXM04590.1\|2704035_2704770_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.49443e-136
CP031282.1\|AXM03687.1\|2744786_2745542_+\|flap-endonuclease-Xni	gnl\|CDD\|181896	PRK09482, PRK09482, flap endonuclease-like protein; Provisional.	1.44833e-177
CP031282.1\|AXM03689.1\|2746688_2747084_-\|DUF423-domain-containing-protein	gnl\|CDD\|182798	PRK10873, PRK10873, hypothetical protein; Provisional.	1.99951e-78
CP031282.1\|AXM04591.1\|2737512_2737842_-\|YqcC-family-protein	gnl\|CDD\|225640	COG3098, COG3098, Uncharacterized protein conserved in bacteria [Function unknown].	5.35412e-45
CP031282.1\|AXM03686.1\|2743307_2744675_+\|L-serine-ammonia-lyase	gnl\|CDD\|273233	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form. This enzyme is also called serine deaminase and L-serine dehydratase 1. L-serine ammonia-lyase converts serine into pyruvate in the gluconeogenesis pathway from serine. This enzyme is comprised of a single chain in Escherichia coli, Mycobacterium tuberculosis, and several other species, but has separate alpha and beta chains in Bacillus subtilis and related species. The beta and alpha chains are homologous to the N-terminal and C-terminal regions, respectively, but are rather deeply branched in a UPGMA tree. This enzyme requires iron and dithiothreitol for activation in vitro, and is a predicted 4Fe-4S protein. Escherichia coli Pseudomonas aeruginosa have two copies of this protein. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	0
CP031282.1\|AXM03681.1\|2712296_2712509_-\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.06944e-10
CP031282.1\|AXM03678.1\|2708669_2709035_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	9.8593e-60
CP031282.1\|AXM03682.1\|2717827_2719126_-\|enolase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
CP031282.1\|AXM03676.1\|2703616_2703769_-\|type-I-toxin-antitoxin-system-hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
CP031282.1\|AXM03673.1\|2694855_2695149_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	3.0872e-65
CP031282.1\|AXM03688.1\|2745595_2746696_-\|23S-rRNA-(cytidine(2498)-2'-O)-methyltransferase-RlmM	gnl\|CDD\|236971	PRK11760, PRK11760, putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional.	0
CP031282.1\|AXM03684.1\|2733387_2733651_+\|hypothetical-protein	gnl\|CDD\|275016	TIGR04154, archaeo_STT3, oligosaccharyl transferase, archaeosortase A system-associated. Members of this protein family occur, one to three members per genome, in the same species of Euryarchaeota as contain the predicted protein-sorting enzyme archaeosortase (TIGR04125) and its cognate protein-sorting signal PGF-CTERM (TIGR04126).	0.00597662
CP031282.1\|AXM03677.1\|2706554_2708354_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
CP031282.1\|AXM03675.1\|2698540_2699077_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	4.26268e-28
CP031282.1\|AXM03685.1\|2736730_2737513_-\|tRNA-pseudouridine(65)-synthase-TruC	gnl\|CDD\|182971	PRK11112, PRK11112, tRNA pseudouridine synthase C; Provisional.	0
CP031282.1\|AXM03680.1\|2711783_2712131_-\|transposase	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	5.69907e-48
CP031282.1\|AXM03674.1\|2695048_2696068_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.84789e-156

>CP031282.1|AXM03681.1|2712296_2712509_-|transposase
MRAKERFPRKHYSPEFKMELVRLALEEEGSIAALARKHDVNDNLLFKWIRLWQREGGSVGPEKTHRRFLP
>CP031282.1|AXM03680.1|2711783_2712131_-|transposase
MINLPAGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFIFRGRSGSQVKLLWSTGDGLCPLTKRLERGRFARSSARDGKVFLTPAQLAMLMEGIDWRQPKRLLTSLTML
>CP031282.1|AXM03679.1|2709395_2709659_-|hypothetical-protein
MSTLMEKECLLNGVSQNIAFLSKLSEMVYNSQNEELQHEIYELVSYKDYLYSTGHELVDFQEGVLRFQKIRIKYRQELKELGYPVGN
>CP031282.1|AXM03678.1|2708669_2709035_+|6-carboxytetrahydropterin-synthase-QueD
MMSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRGE
>CP031282.1|AXM03677.1|2706554_2708354_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALTATPAPAAEMPGITIISASQTGNARRVAETLRDDLLAAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKSKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGAGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
>CP031282.1|AXM04590.1|2704035_2704770_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVLLTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>CP031282.1|AXM03676.1|2703616_2703769_-|type-I-toxin-antitoxin-system-hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>CP031282.1|AXM03675.1|2698540_2699077_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWHEELQEKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKVEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSEGRFSRLSAVKTPDDLLRQLRRAVKLLNGSVNLISLADDIFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQN
>CP031282.1|AXM03674.1|2695048_2696068_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSIVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAADMLPPAIPEPETLGDIGHRGAAGEHGRGCYRKCPAALTWTARNLAPGSACRCVCW
>CP031282.1|AXM03673.1|2694855_2695149_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQISQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>CP031282.1|AXM03682.1|2717827_2719126_-|enolase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>CP031282.1|AXM03683.1|2725597_2728354_+|two-component-sensor-histidine-kinase-BarA
MTNYSLRARMMILILAPTVLIGLLLSLFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMNLQNRESIGQLISVLHRRHSDIVRAISVFDENNHLFVTSNFHLDPSAMQLSSGAPFPRQLSVTRNGDVMILRTPIISESYSPDESPSSEAKNSQNMLGYVALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLTIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKGDVPDNVIGDPLRLQQIITNLVGNAIKFTERGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVIYSPTFSALPESHYDIMLLGIAVTFREPLTLHHERLDKAVAMTDFLLLALPCHAQVNAEKLKQEGVGACLLKPLTSTRLLPALKEFGNKNQIHSLSSTDENKLAMTVMAVDDNPANLKLIGALLEDKVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPDVNEVMVNQNTTLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENTDGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPEFLELLDEMDNVAREAKKILG
>CP031282.1|AXM03684.1|2733387_2733651_+|hypothetical-protein
MVKSFLSTPVINCCFNLLLYLFPGIFGFVISCAIYIFLQTLVLLPRKKKRNYPLFAVVAFVVSSSIFFLFRFGFDILLPAGVMGALL
>CP031282.1|AXM03685.1|2736730_2737513_-|tRNA-pseudouridine(65)-synthase-TruC
MLEILYQDEWLVAVNKPSGWLVHRSWLDRDEKVVVMQTVRDQIGQHVFTAHRLDRPTSGVLLMGLSSEAGRLLAQQFEQHQIQKRYHAIVRGWLMEEAVLDYPLVEELDKIADKYAREDKGPQPAVTQYRGLATVEMPVATGRYPTTRYGLVELEPKTGRKHQLRRHLAHLRHPIIGDSKHGDLRQNRSGAEHFGLQRLMLHASQLSLTHPFTGELLTIHAGLDDIWMQALSQFGWRGLLPENERVEFSGPAVQDEEISS
>CP031282.1|AXM04591.1|2737512_2737842_-|YqcC-family-protein
MMTHEQVRQQLLVLESLLREHQFWQTEAPQAHQFTSTQPFFMDTMEPLEWLQWVLIPRMHALLDSHQPLPDAFAVAPYYEMALENDHPQRELLLAELQKLDALFADDAN
>CP031282.1|AXM04592.1|2741960_2743250_+|HAAAP-family-serine/threonine-permease
METTQTSTIVSKDSRSAWRKTDTMWMLGLYGTAIGAGVLFLPINAGVGGMIPLIIMAILAFPMTFFAHRGLTRFVLSGKNPGEDITEVVEEHFGIGAGKLITLLYFFAIYPILLVYSVAITNTVESFMTHQLGMTPPPRAILSLILIVGMMTIVRFGEQMIVKAMSILVFPFVGVLMLLALYLIPQWNGAALETLSLDTASATGNGLWMTLWLAIPVMVFSFNHSPIISSFAVAKREEYGDMAEKKCSKILAFAHIMMVLTVMFFVFSCVLSLSPADLAAAKEQNISILSYLANHFNAPIIAWMAPIIAIIAITKSFLGHYLGAREGFNGMVIKSLRGKGKSIEINKLNRITALFMLVTTWIVATLNPSILGMIETLGGPIIAMILFLMPMYAIQKVPAMRKYSGHISNVFVVVMGLIAISAIFYSLFS
>CP031282.1|AXM03686.1|2743307_2744675_+|L-serine-ammonia-lyase
MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARNLLKDVTRVVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDIDSIPGFIQDVNTHGRLMVANGQHEVEFPVDQCMNFHADNLSLHENGMRITALAGDKVVYSQTYYSIGGGFIVDEEHFGQQDSAPVEVPYPYSSAADLQKHCQETGLSLSGLMMKNELALHSKEELEQHLANVWEVMRGGIERGISTEGVLPGKLRVPRRAAALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENAAGGRVVTAPTNGACGIIPAVLAYYDKFIREVNANSLARYLLVASAIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGASPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPCIERNAIAAVKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMKIVACD
>CP031282.1|AXM03687.1|2744786_2745542_+|flap-endonuclease-Xni
MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHVVAVFDDENRNSGWRHQRLPDYKAGRPPMPDELHNEMPTLRAAFEQRGVPCWSATGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLEMHKEMAFLCRDIARLQTDVHIDGNLQQLRLKR
>CP031282.1|AXM03688.1|2745595_2746696_-|23S-rRNA-(cytidine(2498)-2'-O)-methyltransferase-RlmM
MNKVVLLCRPGFEKECAAEITDKAGRQEIFGFARVKENAGYVIYECYQAEDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPCCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRNNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER
>CP031282.1|AXM03689.1|2746688_2747084_-|DUF423-domain-containing-protein
MTSRFMLIFAAISGFIFVALGAFGAHVLSKTLGVVEMGWIQTGLEYQAFHTLAILGLAVAMQRRISIWFYWSSVFLALGTVLFSGSLYCLALSHLRLWAYVTPVGGVSFLAGWVLMLIGAIRLKRKGVSHE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP031282_2	2.6\|2694639\|31\|CP031282\|CRISPRCasFinder	2694639-2694669	31	NZ_CP030373	Salinibacter ruber strain RM158 plasmid pSR47, complete sequence	24989-25019	7	0.774
CP031282_1	1.1\|2041711\|30\|CP031282\|CRISPRCasFinder	2041711-2041740	30	NZ_CP045060	Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence	9738-9767	8	0.733
CP031282_1	1.1\|2041711\|30\|CP031282\|CRISPRCasFinder	2041711-2041740	30	NZ_CP045053	Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence	9739-9768	8	0.733
CP031282_1	1.1\|2041711\|30\|CP031282\|CRISPRCasFinder	2041711-2041740	30	NZ_CP045057	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence	9738-9767	8	0.733
CP031282_1	1.3\|2041719\|30\|CP031282\|PILER-CR	2041719-2041748	30	NZ_CP045060	Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence	9738-9767	8	0.733
CP031282_1	1.3\|2041719\|30\|CP031282\|PILER-CR	2041719-2041748	30	NZ_CP045053	Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence	9739-9768	8	0.733
CP031282_1	1.3\|2041719\|30\|CP031282\|PILER-CR	2041719-2041748	30	NZ_CP045057	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence	9738-9767	8	0.733
CP031282_2	2.4\|2694518\|32\|CP031282\|CRISPRCasFinder	2694518-2694549	32	NC_048182	Edwardsiella virus pEt-SU, complete genome	138506-138537	8	0.75
CP031282_2	2.6\|2694639\|31\|CP031282\|CRISPRCasFinder	2694639-2694669	31	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	490135-490165	8	0.742
CP031282_2	2.13\|2694639\|32\|CP031282\|CRT	2694639-2694670	32	NZ_CP030373	Salinibacter ruber strain RM158 plasmid pSR47, complete sequence	24989-25020	8	0.75
CP031282_1	1.2\|2041771\|30\|CP031282\|CRISPRCasFinder	2041771-2041800	30	NZ_CP046163	Vibrio sp. THAF191c plasmid pTHAF191c_b, complete sequence	644947-644976	9	0.7
CP031282_1	1.2\|2041771\|30\|CP031282\|CRISPRCasFinder	2041771-2041800	30	NZ_CP046066	Vibrio sp. THAF191d plasmid pTHAF191d_b, complete sequence	828923-828952	9	0.7
CP031282_1	1.2\|2041771\|30\|CP031282\|CRISPRCasFinder	2041771-2041800	30	NZ_CP045356	Vibrio sp. THAF64 plasmid pTHAF64_a, complete sequence	931573-931602	9	0.7
CP031282_1	1.4\|2041779\|30\|CP031282\|PILER-CR	2041779-2041808	30	NZ_CP046163	Vibrio sp. THAF191c plasmid pTHAF191c_b, complete sequence	644947-644976	9	0.7
CP031282_1	1.4\|2041779\|30\|CP031282\|PILER-CR	2041779-2041808	30	NZ_CP046066	Vibrio sp. THAF191d plasmid pTHAF191d_b, complete sequence	828923-828952	9	0.7
CP031282_1	1.4\|2041779\|30\|CP031282\|PILER-CR	2041779-2041808	30	NZ_CP045356	Vibrio sp. THAF64 plasmid pTHAF64_a, complete sequence	931573-931602	9	0.7
CP031282_2	2.1\|2694339\|31\|CP031282\|CRISPRCasFinder	2694339-2694369	31	NZ_CP009112	Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence	821512-821542	9	0.71
CP031282_2	2.7\|2694699\|32\|CP031282\|CRISPRCasFinder	2694699-2694730	32	NZ_CP023479	Klebsiella quasipneumoniae strain KPC142 plasmid pKQPS142a, complete sequence	62371-62402	9	0.719
CP031282_2	2.7\|2694699\|32\|CP031282\|CRISPRCasFinder	2694699-2694730	32	NZ_CP031796	Klebsiella pneumoniae strain INF125-sc-2279943 plasmid unnamed1, complete sequence	85843-85874	9	0.719
CP031282_2	2.7\|2694699\|32\|CP031282\|CRISPRCasFinder	2694699-2694730	32	NZ_CP034130	Klebsiella quasipneumoniae strain G4584 plasmid pG4584_218.9Kb, complete sequence	63992-64023	9	0.719
CP031282_2	2.7\|2694699\|32\|CP031282\|CRISPRCasFinder	2694699-2694730	32	NZ_CP034138	Klebsiella quasipneumoniae subsp. similipneumoniae strain G747 plasmid pG747_218.9Kb, complete sequence	63991-64022	9	0.719
CP031282_2	2.11\|2694518\|33\|CP031282\|CRT	2694518-2694550	33	NC_048182	Edwardsiella virus pEt-SU, complete genome	138506-138538	9	0.727
CP031282_2	2.13\|2694639\|32\|CP031282\|CRT	2694639-2694670	32	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	490135-490166	9	0.719
CP031282_4	4.1\|2712615\|32\|CP031282\|CRISPRCasFinder	2712615-2712646	32	NZ_CP049248	Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed2, complete sequence	14347-14378	9	0.719
CP031282_4	4.4\|2712796\|32\|CP031282\|CRISPRCasFinder	2712796-2712827	32	MK448767	Streptococcus phage Javan467, complete genome	2874-2905	9	0.719
CP031282_4	4.4\|2712796\|32\|CP031282\|CRISPRCasFinder	2712796-2712827	32	MK448771	Streptococcus phage Javan481, complete genome	2874-2905	9	0.719
CP031282_4	4.4\|2712796\|32\|CP031282\|CRISPRCasFinder	2712796-2712827	32	MK448942	Streptococcus phage Javan448, complete genome	2874-2905	9	0.719
CP031282_4	4.4\|2712796\|32\|CP031282\|CRISPRCasFinder	2712796-2712827	32	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	2979-3010	9	0.719
CP031282_4	4.4\|2712796\|32\|CP031282\|CRISPRCasFinder	2712796-2712827	32	MK448964	Streptococcus phage Javan502, complete genome	2873-2904	9	0.719
CP031282_4	4.4\|2712796\|32\|CP031282\|CRISPRCasFinder	2712796-2712827	32	MK448943	Streptococcus phage Javan450, complete genome	2874-2905	9	0.719
CP031282_4	4.4\|2712796\|32\|CP031282\|CRISPRCasFinder	2712796-2712827	32	MK448972	Streptococcus phage Javan520, complete genome	2874-2905	9	0.719
CP031282_4	4.4\|2712796\|32\|CP031282\|CRISPRCasFinder	2712796-2712827	32	MK448786	Streptococcus phage Javan509, complete genome	2874-2905	9	0.719
CP031282_4	4.4\|2712796\|32\|CP031282\|CRISPRCasFinder	2712796-2712827	32	MK448774	Streptococcus phage Javan487, complete genome	2874-2905	9	0.719
CP031282_4	4.1\|2712615\|32\|CP031282\|CRISPRCasFinder	2712615-2712646	32	MN855988	Bacteriophage sp. isolate 279, partial genome	7601-7632	11	0.656
CP031282_4	4.4\|2712796\|32\|CP031282\|CRISPRCasFinder	2712796-2712827	32	NZ_CP020695	Sulfitobacter sp. D7 plasmid p1SUD7, complete sequence	138278-138309	11	0.656

1. spacer 2.6|2694639|31|CP031282|CRISPRCasFinder matches to NZ_CP030373 (Salinibacter ruber strain RM158 plasmid pSR47, complete sequence) position: , mismatch: 7, identity: 0.774

tgttccaggtcctccggatcaacctgaaatt	CRISPR spacer
cgttccaggtccaccggatgaaccagctctt	Protospacer
.*********** ****** **** *   **

2. spacer 1.1|2041711|30|CP031282|CRISPRCasFinder matches to NZ_CP045060 (Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence) position: , mismatch: 8, identity: 0.733

ggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
accgggcgggtggaacatgttaccaggaca	Protospacer
. .***********..********** . *

3. spacer 1.1|2041711|30|CP031282|CRISPRCasFinder matches to NZ_CP045053 (Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence) position: , mismatch: 8, identity: 0.733

ggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
accgggcgggtggaacatgttaccaggaca	Protospacer
. .***********..********** . *

4. spacer 1.1|2041711|30|CP031282|CRISPRCasFinder matches to NZ_CP045057 (Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence) position: , mismatch: 8, identity: 0.733

ggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
accgggcgggtggaacatgttaccaggaca	Protospacer
. .***********..********** . *

5. spacer 1.3|2041719|30|CP031282|PILER-CR matches to NZ_CP045060 (Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence) position: , mismatch: 8, identity: 0.733

ggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
accgggcgggtggaacatgttaccaggaca	Protospacer
. .***********..********** . *

6. spacer 1.3|2041719|30|CP031282|PILER-CR matches to NZ_CP045053 (Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence) position: , mismatch: 8, identity: 0.733

ggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
accgggcgggtggaacatgttaccaggaca	Protospacer
. .***********..********** . *

7. spacer 1.3|2041719|30|CP031282|PILER-CR matches to NZ_CP045057 (Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence) position: , mismatch: 8, identity: 0.733

ggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
accgggcgggtggaacatgttaccaggaca	Protospacer
. .***********..********** . *

8. spacer 2.4|2694518|32|CP031282|CRISPRCasFinder matches to NC_048182 (Edwardsiella virus pEt-SU, complete genome) position: , mismatch: 8, identity: 0.75

cacgaccagtgccaccagaattaataattttt	CRISPR spacer
cccagttagtgccaccagaagtaataatgtta	Protospacer
* *....************* ******* **

9. spacer 2.6|2694639|31|CP031282|CRISPRCasFinder matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 8, identity: 0.742

tgttccaggtcctccggatcaacctgaaatt	CRISPR spacer
cggtccagatcctctggatcaacctgatcac	Protospacer
.* *****.*****.************   .

10. spacer 2.13|2694639|32|CP031282|CRT matches to NZ_CP030373 (Salinibacter ruber strain RM158 plasmid pSR47, complete sequence) position: , mismatch: 8, identity: 0.75

tgttccaggtcctccggatcaacctgaaattt	CRISPR spacer
cgttccaggtccaccggatgaaccagctcttc	Protospacer
.*********** ****** **** *   **.

11. spacer 1.2|2041771|30|CP031282|CRISPRCasFinder matches to NZ_CP046163 (Vibrio sp. THAF191c plasmid pTHAF191c_b, complete sequence) position: , mismatch: 9, identity: 0.7

gcaaagggcttttctgccatattcaccatt	CRISPR spacer
ggcgtatgcttttctgccagattcaccacg	Protospacer
*  . . ************ ********.

12. spacer 1.2|2041771|30|CP031282|CRISPRCasFinder matches to NZ_CP046066 (Vibrio sp. THAF191d plasmid pTHAF191d_b, complete sequence) position: , mismatch: 9, identity: 0.7

gcaaagggcttttctgccatattcaccatt	CRISPR spacer
ggcgtatgcttttctgccagattcaccacg	Protospacer
*  . . ************ ********.

13. spacer 1.2|2041771|30|CP031282|CRISPRCasFinder matches to NZ_CP045356 (Vibrio sp. THAF64 plasmid pTHAF64_a, complete sequence) position: , mismatch: 9, identity: 0.7

gcaaagggcttttctgccatattcaccatt	CRISPR spacer
ggcgtatgcttttctgccagattcaccacg	Protospacer
*  . . ************ ********.

14. spacer 1.4|2041779|30|CP031282|PILER-CR matches to NZ_CP046163 (Vibrio sp. THAF191c plasmid pTHAF191c_b, complete sequence) position: , mismatch: 9, identity: 0.7

gcaaagggcttttctgccatattcaccatt	CRISPR spacer
ggcgtatgcttttctgccagattcaccacg	Protospacer
*  . . ************ ********.

15. spacer 1.4|2041779|30|CP031282|PILER-CR matches to NZ_CP046066 (Vibrio sp. THAF191d plasmid pTHAF191d_b, complete sequence) position: , mismatch: 9, identity: 0.7

gcaaagggcttttctgccatattcaccatt	CRISPR spacer
ggcgtatgcttttctgccagattcaccacg	Protospacer
*  . . ************ ********.

16. spacer 1.4|2041779|30|CP031282|PILER-CR matches to NZ_CP045356 (Vibrio sp. THAF64 plasmid pTHAF64_a, complete sequence) position: , mismatch: 9, identity: 0.7

gcaaagggcttttctgccatattcaccatt	CRISPR spacer
ggcgtatgcttttctgccagattcaccacg	Protospacer
*  . . ************ ********.

17. spacer 2.1|2694339|31|CP031282|CRISPRCasFinder matches to NZ_CP009112 (Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence) position: , mismatch: 9, identity: 0.71

aatatctgttgtaaccgtggtgagtgcatta	CRISPR spacer
ggttactgttgtaaccgtggtgagcgcggct	Protospacer
..*  *******************.**. .

18. spacer 2.7|2694699|32|CP031282|CRISPRCasFinder matches to NZ_CP023479 (Klebsiella quasipneumoniae strain KPC142 plasmid pKQPS142a, complete sequence) position: , mismatch: 9, identity: 0.719

cgacgcgcggcacgattaaaccaaaatggccg	CRISPR spacer
aaacgcgccgcacgattacaccaaattcaatg	Protospacer
 .****** ********* ****** * . .*

19. spacer 2.7|2694699|32|CP031282|CRISPRCasFinder matches to NZ_CP031796 (Klebsiella pneumoniae strain INF125-sc-2279943 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cgacgcgcggcacgattaaaccaaaatggccg	CRISPR spacer
aaacgcgccgcacgattacaccaaattcaatg	Protospacer
 .****** ********* ****** * . .*

20. spacer 2.7|2694699|32|CP031282|CRISPRCasFinder matches to NZ_CP034130 (Klebsiella quasipneumoniae strain G4584 plasmid pG4584_218.9Kb, complete sequence) position: , mismatch: 9, identity: 0.719

cgacgcgcggcacgattaaaccaaaatggccg	CRISPR spacer
aaacgcgccgcacgattacaccaaattcaatg	Protospacer
 .****** ********* ****** * . .*

21. spacer 2.7|2694699|32|CP031282|CRISPRCasFinder matches to NZ_CP034138 (Klebsiella quasipneumoniae subsp. similipneumoniae strain G747 plasmid pG747_218.9Kb, complete sequence) position: , mismatch: 9, identity: 0.719

cgacgcgcggcacgattaaaccaaaatggccg	CRISPR spacer
aaacgcgccgcacgattacaccaaattcaatg	Protospacer
 .****** ********* ****** * . .*

22. spacer 2.11|2694518|33|CP031282|CRT matches to NC_048182 (Edwardsiella virus pEt-SU, complete genome) position: , mismatch: 9, identity: 0.727

cacgaccagtgccaccagaattaataatttttt	CRISPR spacer
cccagttagtgccaccagaagtaataatgttag	Protospacer
* *....************* ******* **

23. spacer 2.13|2694639|32|CP031282|CRT matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 9, identity: 0.719

tgttccaggtcctccggatcaacctgaaattt	CRISPR spacer
cggtccagatcctctggatcaacctgatcacc	Protospacer
.* *****.*****.************   ..

24. spacer 4.1|2712615|32|CP031282|CRISPRCasFinder matches to NZ_CP049248 (Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

atccgcgagatcaacagtggttgcgagatcga	CRISPR spacer
ctgcgcaagatcaacagtgattgcgatcaggc	Protospacer
 * ***.************.******    *

25. spacer 4.4|2712796|32|CP031282|CRISPRCasFinder matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 9, identity: 0.719

cgccgagccagacaaataagatactcacaaaa	CRISPR spacer
aacaaagctagactaataagatactcacctga	Protospacer
 .* .***.**** **************  .*

26. spacer 4.4|2712796|32|CP031282|CRISPRCasFinder matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 9, identity: 0.719

cgccgagccagacaaataagatactcacaaaa	CRISPR spacer
aacaaagctagactaataagatactcacctga	Protospacer
 .* .***.**** **************  .*

27. spacer 4.4|2712796|32|CP031282|CRISPRCasFinder matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 9, identity: 0.719

cgccgagccagacaaataagatactcacaaaa	CRISPR spacer
aacaaagctagactaataagatactcacctga	Protospacer
 .* .***.**** **************  .*

28. spacer 4.4|2712796|32|CP031282|CRISPRCasFinder matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 9, identity: 0.719

cgccgagccagacaaataagatactcacaaaa	CRISPR spacer
aacaaagctagactaataagatactcacctga	Protospacer
 .* .***.**** **************  .*

29. spacer 4.4|2712796|32|CP031282|CRISPRCasFinder matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 9, identity: 0.719

cgccgagccagacaaataagatactcacaaaa	CRISPR spacer
aacaaagctagactaataagatactcacctga	Protospacer
 .* .***.**** **************  .*

30. spacer 4.4|2712796|32|CP031282|CRISPRCasFinder matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 9, identity: 0.719

cgccgagccagacaaataagatactcacaaaa	CRISPR spacer
aacaaagctagactaataagatactcacctga	Protospacer
 .* .***.**** **************  .*

31. spacer 4.4|2712796|32|CP031282|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 9, identity: 0.719

cgccgagccagacaaataagatactcacaaaa	CRISPR spacer
aacaaagctagactaataagatactcacctga	Protospacer
 .* .***.**** **************  .*

32. spacer 4.4|2712796|32|CP031282|CRISPRCasFinder matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 9, identity: 0.719

cgccgagccagacaaataagatactcacaaaa	CRISPR spacer
aacaaagctagactaataagatactcacctga	Protospacer
 .* .***.**** **************  .*

33. spacer 4.4|2712796|32|CP031282|CRISPRCasFinder matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 9, identity: 0.719

cgccgagccagacaaataagatactcacaaaa	CRISPR spacer
aacaaagctagactaataagatactcacctga	Protospacer
 .* .***.**** **************  .*

34. spacer 4.1|2712615|32|CP031282|CRISPRCasFinder matches to MN855988 (Bacteriophage sp. isolate 279, partial genome) position: , mismatch: 11, identity: 0.656

atccgcgagatcaacagtggttgcgagatcga	CRISPR spacer
cggcgtgatatcaacagtggttgcgaccggag	Protospacer
   **.** *****************    ..

35. spacer 4.4|2712796|32|CP031282|CRISPRCasFinder matches to NZ_CP020695 (Sulfitobacter sp. D7 plasmid p1SUD7, complete sequence) position: , mismatch: 11, identity: 0.656

cgccgagccagacaaataagatactcacaaaa	CRISPR spacer
tcgtgagccagaccaataagatcctcatgccc	Protospacer
.  .********* ******** ****..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

308087 : 474573

Enterobacteria_phage(46.67%)

tRNA,protease,plate,lysis,integrase,transposase,tail

attL 308028:308075|attR 470725:470745

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
308028:308075	attL	NA	NA	NA	NA
AXM02750.1\|308087_309248_-\|integrase	site-specific integrase	K7P7R5	Enterobacteria_phage	1.2e-228	100.0
308028:308075	attL	NA	NA	NA	NA
AXM02751.1\|309540_309819_-	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	4.9e-48	97.8
AXM02752.1\|311116_311335_-	TraR/DksA family transcriptional regulator	M1FQT7	Enterobacteria_phage	2.2e-35	97.2
AXM02753.1\|311433_311715_-	cell division protein ZapA	A0A0P0ZE02	Stx2-converting_phage	5.5e-47	98.9
AXM02754.1\|311725_312283_-	phage N-6-adenine-methyltransferase	E5AGF8	Erwinia_phage	7.8e-61	61.7
AXM02755.1\|312432_313113_-	exonuclease	A0A0N6WET1	Escherichia_phage	1.6e-132	100.0
AXM02756.1\|313109_313895_-	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
AXM04511.1\|314270_314477_-	cell division inhibitor protein	K7P6H3	Enterobacteria_phage	3.5e-27	83.8
AXM02757.1\|314794_314983_-	hypothetical protein	NA	NA	NA	NA
AXM04512.1\|316495_317188_-	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	1.5e-109	86.1
AXM02758.1\|317298_317526_+	transcriptional regulator	Q76H55	Enterobacteria_phage	3.8e-22	69.0
AXM02759.1\|317556_318096_+	regulator	M9NZI6	Enterobacteria_phage	8.9e-62	66.7
AXM02760.1\|318092_319136_+	Replication protein O	A0A0M5M7Y1	Salmonella_phage	6.5e-109	63.7
AXM02761.1\|319107_319809_+	Replication protein P	M1FJ72	Enterobacteria_phage	1.6e-127	97.9
AXM02762.1\|322220_322322_+	hypothetical protein	NA	NA	NA	NA
AXM02763.1\|322318_322774_+	hypothetical protein	I6PD71	Cronobacter_phage	2.7e-59	66.9
AXM02764.1\|322773_322944_+	hypothetical protein	G8C7V4	Escherichia_phage	1.8e-13	63.6
AXM02765.1\|322936_323227_+	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	6.7e-48	95.8
AXM02766.1\|323223_323586_+	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	3.3e-60	95.7
AXM02767.1\|323807_324185_+	antitermination protein	Q777W5	Enterobacteria_phage	7.3e-55	84.2
AXM02768.1\|325055_326015_+	DUF523 and DUF1722 domain-containing protein	NA	NA	NA	NA
AXM02769.1\|326364_326499_+	AraC family transcriptional regulator	NA	NA	NA	NA
AXM02770.1\|326507_327095_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AXM02771.1\|327409_327688_+\|transposase	transposase	A0A0P0ZBP6	Stx2-converting_phage	5.6e-44	97.8
AXM02772.1\|327684_328032_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
AXM02773.1\|329729_329945_+\|lysis	lysis protein S	A5LH82	Enterobacteria_phage	1.2e-33	98.6
AXM02774.1\|329944_330442_+	lysozyme	M1FJA0	Enterobacteria_phage	1.2e-89	97.6
AXM02775.1\|330658_330841_+	hypothetical protein	A0A0P0ZE50	Stx2-converting_phage	1.5e-13	67.8
AXM02776.1\|330931_331225_-	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	2.0e-44	91.8
AXM04513.1\|331814_332321_+	DUF1441 family protein	K7PJY2	Enterobacterial_phage	6.9e-48	64.6
AXM02777.1\|334435_334651_+	hypothetical protein	NA	NA	NA	NA
AXM02778.1\|338267_338597_+	DUF2190 family protein	S5MQJ5	Escherichia_phage	3.6e-13	40.7
AXM02779.1\|342278_342785_+\|tail	phage tail protein	A0A1B2LRS4	Wolbachia_phage	3.6e-12	30.9
AXM02780.1\|342843_343143_+\|tail	phage tail assembly protein	NA	NA	NA	NA
AXM02781.1\|343244_344036_+	hypothetical protein	R9TRP8	Vibrio_phage	2.0e-22	35.7
AXM02782.1\|344073_344373_+	hypothetical protein	A0A2I7R3J9	Vibrio_phage	2.5e-05	44.8
AXM02783.1\|344418_344709_+	hypothetical protein	NA	NA	NA	NA
AXM02784.1\|344820_345147_+	hypothetical protein	NA	NA	NA	NA
AXM02785.1\|345587_345803_+\|tail	phage tail protein	R9TR63	Vibrio_phage	2.2e-11	47.1
AXM02786.1\|346961_347315_+\|plate	baseplate assembly protein	E5FFH4	Burkholderia_phage	5.9e-22	50.0
AXM02787.1\|350453_351038_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	3.0e-71	65.5
AXM04514.1\|351448_351631_-	hypothetical protein	NA	NA	NA	NA
351480:351527	attR	NA	NA	NA	NA
AXM02788.1\|351689_352859_+	DUF4102 domain-containing protein	Q7M297	Enterobacteria_phage	9.7e-146	62.4
351480:351527	attR	NA	NA	NA	NA
AXM02789.1\|356384_356957_-	Polarity suppression protein	Q7M2A1	Enterobacteria_phage	1.8e-97	99.5
AXM02790.1\|356971_357217_-	hypothetical protein	Q7M294	Enterobacteria_phage	1.8e-41	100.0
AXM04515.1\|358545_358827_+	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	3.1e-34	100.0
AXM02791.1\|359341_359629_+	Derepression protein	Q7M2A0	Enterobacteria_phage	8.6e-48	97.9
AXM02792.1\|359621_360068_+	hypothetical protein	Q7M298	Enterobacteria_phage	2.0e-59	99.0
AXM02793.1\|362916_363663_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	5.0e-55	48.5
AXM02794.1\|365671_365842_+\|integrase	attP region and P4int integrase	NA	NA	NA	NA
AXM02795.1\|366349_366451_-	hypothetical protein	NA	NA	NA	NA
AXM02796.1\|367536_368765_-\|transposase	IS3-like element IS2 family transposase	Q9ZXG3	Shigella_phage	1.3e-177	99.3
AXM02797.1\|369245_370235_-	aldo/keto reductase	NA	NA	NA	NA
AXM02798.1\|370261_371113_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.2e-47	38.9
AXM02799.1\|371392_371872_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AXM02800.1\|373016_374108_+	EAL domain-containing protein	NA	NA	NA	NA
AXM02801.1\|374408_374759_+	hypothetical protein	NA	NA	NA	NA
AXM02802.1\|379300_379972_-	FadR family transcriptional regulator	NA	NA	NA	NA
AXM02803.1\|381590_382223_-	hypothetical protein	NA	NA	NA	NA
AXM02804.1\|385537_386707_+	2-methylcitrate synthase	NA	NA	NA	NA
AXM02805.1\|394768_394948_-	hypothetical protein	NA	NA	NA	NA
AXM02806.1\|399860_402869_+	autotransporter outer membrane beta-barrel domain-containing protein	NA	NA	NA	NA
AXM02807.1\|402956_403580_+	hydrogen peroxide resistance inhibitor IprA	NA	NA	NA	NA
AXM02808.1\|405275_406463_+	peptide antibiotic transporter SbmA	NA	NA	NA	NA
AXM04516.1\|408370_409450_-	D-alanine--D-alanine ligase	NA	NA	NA	NA
AXM02809.1\|415526_415718_+	hypothetical protein	NA	NA	NA	NA
AXM02810.1\|416709_416994_+	pyrimidine/purine nucleoside phosphorylase	NA	NA	NA	NA
AXM02811.1\|418067_418982_+	fructokinase	NA	NA	NA	NA
AXM02812.1\|424389_425193_+	two-component system sensor histidine kinase PhoR	NA	NA	NA	NA
AXM02813.1\|425877_426078_-	hypothetical protein	NA	NA	NA	NA
AXM02814.1\|430805_431387_-	ACP phosphodiesterase	NA	NA	NA	NA
AXM02815.1\|432597_433725_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	6.1e-89	45.8
AXM04517.1\|433747_434080_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	2.8e-10	33.0
AXM02816.1\|439315_439765_+	transcriptional regulator NrdR	NA	NA	NA	NA
AXM02817.1\|441442_441862_+	N utilization substance protein B	NA	NA	NA	NA
AXM02818.1\|441937_442915_+	thiamine-phosphate kinase	NA	NA	NA	NA
AXM02819.1\|442892_443411_+	phosphatidylglycerophosphatase A	NA	NA	NA	NA
AXM02820.1\|447270_447513_-	exodeoxyribonuclease 7 small subunit	NA	NA	NA	NA
AXM02821.1\|447718_449167_+\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
AXM02822.1\|449772_450684_-	2-dehydropantoate 2-reductase	NA	NA	NA	NA
AXM02823.1\|450851_451343_+	YajQ family cyclic di-GMP-binding protein	NA	NA	NA	NA
AXM02824.1\|456942_457263_-	NIPSNAP family protein	NA	NA	NA	NA
AXM02825.1\|460726_462265_+	sel1 repeat family protein	NA	NA	NA	NA
AXM02826.1\|462515_463406_-	protoheme IX farnesyltransferase	NA	NA	NA	NA
AXM02827.1\|463417_463747_-	cytochrome bo(3) ubiquinol oxidase subunit 4	NA	NA	NA	NA
AXM02828.1\|463746_464361_-	cytochrome bo(3) ubiquinol oxidase subunit 3	NA	NA	NA	NA
AXM02829.1\|466361_467309_-	cytochrome o ubiquinol oxidase subunit II	NA	NA	NA	NA
AXM02830.1\|467951_469427_-	muropeptide MFS transporter AmpG	NA	NA	NA	NA
AXM02831.1\|469470_470016_-	hypothetical protein	NA	NA	NA	NA
AXM02832.1\|470349_470667_+	transcriptional regulator BolA	NA	NA	NA	NA
AXM02833.1\|471007_472306_+	trigger factor	NA	NA	NA	NA
AXM02834.1\|472549_473173_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.9e-64	63.9
AXM02835.1\|473298_474573_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	6.6e-132	56.6

DBSCAN-SWA_2

1861369 : 1870711

Salmonella_phage(28.57%)

transposase,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXM03371.1\|1861369_1862770_-	DNA transfer protein	A0A220NR03	Salmonella_phage	3.8e-149	64.7
AXM03372.1\|1862782_1863436_-	DNA transfer protein	Q716G4	Shigella_phage	5.7e-55	70.5
AXM03373.1\|1863410_1863890_-	DUF2824 family protein	Q2A0B3	Sodalis_phage	1.4e-63	72.1
AXM03374.1\|1864735_1866154_-	hypothetical protein	Q9AYZ4	Salmonella_phage	1.1e-273	98.7
AXM03375.1\|1866163_1866625_-\|head	head DNA stabilization protein	A5VW70	Enterobacteria_phage	6.0e-83	98.7
AXM03376.1\|1868105_1868999_-	scaffolding protein	A0A088CPT0	Enterobacteria_phage	4.8e-129	98.3
AXM04562.1\|1869389_1869596_+	hypothetical protein	NA	NA	NA	NA
AXM03377.1\|1869564_1870711_+\|transposase	IS3 family transposase	Q716C2	Shigella_phage	1.1e-175	97.6

DBSCAN-SWA_3

3020983 : 3082644

Enterobacteria_phage(55.0%)

tRNA,terminase,protease,transposase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXM03816.1\|3020983_3021670_-\|tRNA	tRNA/rRNA methyltransferase	NA	NA	NA	NA
AXM03817.1\|3022067_3022208_-	hypothetical protein	NA	NA	NA	NA
AXM03818.1\|3022303_3023020_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	8.0e-26	32.3
AXM03819.1\|3027305_3028175_+	MDR efflux pump AcrAB transcriptional activator RobA	NA	NA	NA	NA
AXM03820.1\|3029376_3029703_-	trp operon repressor	NA	NA	NA	NA
AXM04599.1\|3031835_3031964_-	methionine aminopeptidase	NA	NA	NA	NA
AXM03821.1\|3033658_3033943_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AXM03822.1\|3033944_3034298_-	addiction module toxin RelE	NA	NA	NA	NA
AXM04600.1\|3035617_3037000_-	DNA repair protein RadA	NA	NA	NA	NA
AXM03823.1\|3038119_3038764_+	protein Smp	NA	NA	NA	NA
AXM03824.1\|3039838_3040102_+	XRE family transcriptional regulator	NA	NA	NA	NA
AXM03825.1\|3043710_3044490_-	deoxyribose-phosphate aldolase	NA	NA	NA	NA
AXM04601.1\|3048036_3049140_-	patatin family protein	NA	NA	NA	NA
AXM03826.1\|3049230_3049410_-	DUF1328 domain-containing protein	A0A0N7CBR2	Salmonella_phage	2.0e-10	64.2
AXM03827.1\|3049518_3050124_-	molecular chaperone OsmY	NA	NA	NA	NA
AXM03828.1\|3052321_3052570_+	damage-inducible protein DinI	A5LH55	Enterobacteria_phage	1.1e-38	100.0
AXM03829.1\|3053177_3053411_+	hypothetical protein	A0A192Y6D5	Salmonella_phage	6.4e-33	88.3
AXM03830.1\|3062095_3062743_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	1.1e-111	97.2
AXM03831.1\|3062640_3063384_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	2.2e-151	99.2
AXM03832.1\|3063389_3064088_-\|tail	phage minor tail protein L	A5LH40	Enterobacteria_phage	3.0e-134	99.6
AXM03833.1\|3064132_3064426_-\|tail	phage tail protein	A5LH39	Enterobacteria_phage	3.5e-52	100.0
AXM03834.1\|3067455_3067785_-\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	7.6e-56	100.0
AXM04602.1\|3068993_3069395_-\|tail	phage tail protein	A0A291AWY2	Escherichia_phage	2.4e-72	99.2
AXM03835.1\|3069980_3070256_-	DNA breaking-rejoining protein	K7PH43	Enterobacteria_phage	2.3e-45	100.0
AXM03836.1\|3070248_3070617_-	DUF2190 family protein	A0A291AWX2	Escherichia_phage	9.7e-52	100.0
AXM03837.1\|3070658_3072782_-\|protease	Clp protease ClpP	A5LH30	Enterobacteria_phage	0.0e+00	99.7
AXM03838.1\|3074136_3074349_-	hypothetical protein	A5LH28	Enterobacteria_phage	1.1e-31	100.0
AXM03839.1\|3074345_3076304_-\|terminase	phage terminase large subunit family protein	A0A291AWY5	Escherichia_phage	0.0e+00	96.8
AXM03840.1\|3076926_3077205_-	hypothetical protein	NA	NA	NA	NA
AXM03841.1\|3077489_3077639_-	hypothetical protein	A0A0K2FJ18	Enterobacteria_phage	2.4e-17	91.8
AXM04603.1\|3078334_3078490_-	hypothetical protein	NA	NA	NA	NA
AXM03842.1\|3078605_3079879_-\|transposase	IS3-like element IS2 family transposase	Q9ZXG3	Shigella_phage	1.4e-177	99.3
AXM04604.1\|3079974_3080163_-	cold-shock protein	NA	NA	NA	NA
AXM03843.1\|3080746_3081244_-	DUF2514 domain-containing protein	A0A291LBG9	Klebsiella_phage	2.2e-06	30.8
AXM04605.1\|3081885_3082146_+	hypothetical protein	NA	NA	NA	NA
AXM03844.1\|3082093_3082429_-	DUF1327 domain-containing protein	Q08JA0	Stx2-converting_phage	3.6e-13	48.6
AXM03845.1\|3082389_3082644_-	DUF1327 domain-containing protein	K7PGU6	Enterobacteria_phage	5.5e-30	88.0

DBSCAN-SWA_4

3086518 : 3095484

Shigella_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXM03847.1\|3086518_3087316_-	KilA-N domain-containing protein	A0A0P0ZCS0	Stx2-converting_phage	9.8e-150	99.2
AXM03848.1\|3087719_3088046_-	LexA family transcriptional regulator	A0A291AWY9	Escherichia_phage	7.8e-53	98.1
AXM03849.1\|3088687_3089188_-	PerC family transcriptional regulator	A0A0P0ZCF0	Stx2-converting_phage	5.7e-87	99.4
AXM03850.1\|3090113_3090293_-	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	7.8e-15	68.5
AXM03851.1\|3090468_3091020_-	protein YmfL	S5FXP0	Shigella_phage	2.2e-100	98.4
AXM03852.1\|3091063_3091264_-	transcriptional regulator	U5P445	Shigella_phage	7.9e-32	100.0
AXM03853.1\|3091354_3092029_+	LexA family transcriptional repressor	U5P0T5	Shigella_phage	1.2e-132	100.0
AXM03854.1\|3092247_3092469_+	hypothetical protein	NA	NA	NA	NA
AXM03855.1\|3092440_3092875_-	hypothetical protein	U5P096	Shigella_phage	8.4e-79	100.0
AXM03856.1\|3092793_3093138_-	hypothetical protein	U5P0J5	Shigella_phage	1.1e-60	97.4
AXM03857.1\|3095289_3095484_+	DNA-binding protein	A5LH59	Enterobacteria_phage	2.2e-31	95.3

DBSCAN-SWA_5

3374318 : 3414568

Burkholderia_phage(54.55%)

plate,tRNA,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXM03995.1\|3374318_3375314_-\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
AXM03996.1\|3376041_3376251_-	CsbD family protein	NA	NA	NA	NA
AXM03997.1\|3376382_3377708_-	MATE family efflux transporter DinF	NA	NA	NA	NA
AXM03998.1\|3377780_3378389_-	repressor LexA	U5P451	Shigella_phage	3.6e-11	43.3
AXM03999.1\|3378498_3378867_-	diacylglycerol kinase	NA	NA	NA	NA
AXM04000.1\|3379037_3381458_+	glycerol-3-phosphate 1-O-acyltransferase	NA	NA	NA	NA
AXM04001.1\|3381513_3382386_-	4-hydroxybenzoate octaprenyltransferase	NA	NA	NA	NA
AXM04002.1\|3383053_3384004_-	maltose operon protein MalM	NA	NA	NA	NA
AXM04003.1\|3384110_3385400_-	maltoporin LamB	NA	NA	NA	NA
AXM04004.1\|3387015_3388206_+	maltose/maltodextrin ABC transporter substrate-binding protein MalE	NA	NA	NA	NA
AXM04005.1\|3393329_3393608_+	hypothetical protein	NA	NA	NA	NA
AXM04620.1\|3393654_3395271_-	YjbH domain-containing protein	NA	NA	NA	NA
AXM04006.1\|3395249_3395750_-	hypothetical protein	NA	NA	NA	NA
AXM04007.1\|3396482_3397121_-	YjbF family lipoprotein	NA	NA	NA	NA
AXM04008.1\|3399772_3401122_+	lysine-sensitive aspartokinase 3	NA	NA	NA	NA
AXM04009.1\|3401266_3402196_+	zeta toxin	NA	NA	NA	NA
AXM04010.1\|3402367_3402712_-	DNA-binding protein	Q6QIE8	Burkholderia_phage	6.3e-21	47.6
AXM04011.1\|3403249_3403537_+	hypothetical protein	Q6QIC8	Burkholderia_phage	3.0e-16	48.6
AXM04012.1\|3403539_3404145_+	lytic transglycosylase domain-containing protein	Q5ZQZ1	Pseudomonas_phage	5.7e-57	56.6
AXM04013.1\|3404157_3404472_+	hypothetical protein	Q6QIC4	Burkholderia_phage	7.1e-19	47.2
AXM04014.1\|3405040_3405238_+	hypothetical protein	NA	NA	NA	NA
AXM04015.1\|3406650_3407175_+\|tail	phage major tail tube protein	Q6QIA9	Burkholderia_phage	7.3e-69	69.0
AXM04016.1\|3407224_3407542_+\|tail	phage tail assembly protein	NA	NA	NA	NA
AXM04017.1\|3407501_3407630_+\|tail	GpE family phage tail protein	NA	NA	NA	NA
AXM04018.1\|3407730_3410130_+\|tail	phage tail tape measure protein	A4JWL0	Burkholderia_virus	1.6e-54	27.8
AXM04019.1\|3410104_3411058_+	chemotaxis protein	A4JWL1	Burkholderia_virus	3.3e-35	50.8
AXM04020.1\|3412302_3413004_+\|plate	phage baseplate assembly protein V	A4JWL4	Burkholderia_virus	5.1e-17	32.8
AXM04021.1\|3413102_3413462_+\|plate	baseplate protein	Q6QIA0	Burkholderia_phage	5.2e-34	62.4
AXM04022.1\|3413452_3414568_+\|plate	baseplate protein	Q6QI99	Burkholderia_phage	2.0e-100	51.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP031282

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection