CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
CP031644	Bacillus anthracis strain MCCC 1A01412 plasmid p1, complete sequence	0 crisprs	NA	2
CP031643	Bacillus anthracis strain MCCC 1A01412 chromosome, complete genome	2 crisprs	cas3,c2c9_V-U4,csa3,WYL,RT,DinG,cas14k,DEDDh,Cas14u_CAS-V	5
CP031645	Bacillus anthracis strain MCCC 1A01412 plasmid p2, complete sequence	0 crisprs	NA	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

579 : 23047

Bacillus_phage(78.26%)

holin,portal,head,tail,terminase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXO96176.1\|579_1155_+	recombinase family protein	I1ZBD6	Salisaeta_icosahedral_phage	1.8e-28	40.3
AXO96177.1\|1261_1441_-	hypothetical protein	A0A1P8CWV7	Bacillus_phage	8.1e-12	57.6
AXO96178.1\|1922_2681_+	hypothetical protein	D2XPX8	Bacillus_virus	2.5e-54	59.8
AXO96179.1\|2677_3907_+\|terminase	PBSX family phage terminase large subunit	A0A059T7K2	Staphylococcus_phage	1.2e-146	62.7
AXO96180.1\|3919_5344_+\|portal	phage portal protein	A0A0S2MVB2	Bacillus_phage	1.3e-256	92.7
AXO96251.1\|5417_6185_+\|head	phage head protein	A0A0S2MVF0	Bacillus_phage	1.2e-136	94.1
AXO96181.1\|6259_6991_+	DUF4355 domain-containing protein	A0A0A7AQU8	Bacillus_phage	6.4e-71	63.1
AXO96182.1\|7107_7953_+	hypothetical protein	A0A0S2MVF8	Bacillus_phage	5.9e-137	87.9
AXO96183.1\|7996_8308_+	hypothetical protein	A0A0A7AQX9	Bacillus_phage	9.7e-45	89.0
AXO96184.1\|8304_8649_+\|head,tail	head-tail adaptor protein	A0A0A7AR32	Bacillus_phage	1.9e-57	92.1
AXO96185.1\|8623_9031_+	HK97 gp10 family phage protein	A0A0A7AQU9	Bacillus_phage	1.9e-64	92.6
AXO96186.1\|9036_9399_+	hypothetical protein	A0A0S2MV90	Bacillus_phage	9.2e-55	89.2
AXO96187.1\|9413_10007_+	hypothetical protein	A0A0S2MV81	Bacillus_phage	3.4e-107	97.5
AXO96188.1\|10053_10482_+	hypothetical protein	A0A0A7AQY2	Bacillus_phage	1.1e-67	93.7
AXO96189.1\|10586_10793_+	hypothetical protein	A0A0A7AQY2	Bacillus_phage	1.4e-31	97.1
AXO96190.1\|10793_13724_+\|tail	phage tail tape measure protein	A0A0A7AR36	Bacillus_phage	7.5e-272	81.4
AXO96191.1\|13734_14487_+\|tail	phage tail protein	A0A0A7RWN1	Clostridium_phage	1.9e-22	30.2
AXO96192.1\|14486_16643_+	hypothetical protein	Q8W5Z5	Listeria_phage	1.3e-82	38.7
AXO96193.1\|16790_17999_+	DUF2479 domain-containing protein	A0A1B1P768	Bacillus_phage	6.0e-66	39.5
AXO96194.1\|18011_18443_+	hypothetical protein	NA	NA	NA	NA
AXO96195.1\|18696_19137_+\|holin	holin	A0A1B1P7S2	Bacillus_phage	4.5e-64	83.6
AXO96196.1\|19136_20147_+	N-acetylmuramoyl-L-alanine amidase	D2XR33	Bacillus_phage	9.0e-100	66.0
AXO96252.1\|20254_20359_+	N-acetylmuramoyl-L-alanine amidase	A0A1B1P878	Bacillus_phage	7.7e-07	86.2
AXO96197.1\|20402_20909_-	protein phosphatase 2C	NA	NA	NA	NA
AXO96198.1\|21443_21785_-	YolD-like family protein	NA	NA	NA	NA
AXO96199.1\|21781_23047_-	Y-family DNA polymerase	O64031	Bacillus_phage	3.9e-108	48.6

DBSCAN-SWA_2

52840 : 67947

Bacillus_phage(76.47%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXO96227.1\|52840_53404_-	DUF4352 domain-containing protein	A0A0S2MVG4	Bacillus_phage	4.6e-37	48.2
AXO96228.1\|53537_53882_-	DUF4064 domain-containing protein	A0A0S2MVJ2	Bacillus_phage	3.2e-49	93.0
AXO96229.1\|53909_54440_-	DUF4352 domain-containing protein	A0A0S2MVG4	Bacillus_phage	2.0e-66	73.3
AXO96230.1\|54560_55262_-	class D sortase	NA	NA	NA	NA
AXO96231.1\|55319_55847_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
AXO96232.1\|56517_56868_-	XRE family transcriptional regulator	A0A0U3SD25	Bacillus_phage	4.9e-21	46.0
AXO96233.1\|56998_57220_+	XRE family transcriptional regulator	A0A0U3SLC2	Bacillus_phage	2.4e-05	55.6
AXO96234.1\|57260_58031_+	phage antirepressor Ant	A0A2H4PQV4	Staphylococcus_phage	1.3e-53	44.0
AXO96235.1\|58846_59521_+	recombinase	A0A0M3ULL1	Bacillus_phage	1.2e-60	57.4
AXO96236.1\|59709_59931_+	hypothetical protein	NA	NA	NA	NA
AXO96237.1\|59931_60768_+	replication protein	V5UQV4	Oenococcus_phage	7.4e-47	44.8
AXO96238.1\|60751_61510_+	AAA family ATPase	U5PVD6	Bacillus_phage	1.1e-36	38.8
AXO96239.1\|61524_61788_+	hypothetical protein	A0A1B1P8D7	Bacillus_phage	4.7e-16	63.8
AXO96240.1\|61744_61990_+	helix-turn-helix domain containing protein	A0A1B1P7W1	Bacillus_phage	4.5e-29	87.2
AXO96241.1\|61986_62250_+	hypothetical protein	A0A0S2GLK4	Bacillus_phage	1.8e-23	62.5
AXO96242.1\|62359_62899_+	hypothetical protein	A0A1I9S5V4	Bacillus_phage	2.8e-71	76.7
AXO96243.1\|63277_63550_-	hypothetical protein	NA	NA	NA	NA
AXO96244.1\|63933_64131_+	hypothetical protein	NA	NA	NA	NA
AXO96245.1\|64152_64338_-	hypothetical protein	A0A288WGN0	Bacillus_phage	3.3e-08	63.0
AXO96246.1\|64448_65078_+	Holliday junction resolvase RecU	A0A2H4J3A4	uncultured_Caudovirales_phage	7.7e-49	60.5
AXO96247.1\|65215_65599_+	ArpU family transcriptional regulator	D2XQ27	Bacillus_virus	2.2e-46	77.3
AXO96248.1\|65697_66549_+	DUF4393 domain-containing protein	NA	NA	NA	NA
AXO96249.1\|67725_67947_+	cell division protein FtsK	A0A1B1P7C1	Bacillus_phage	5.7e-07	48.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP031643

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CRISPR-Cas detection and classification

Crispr_ID: CP031643_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031643_1

452753-452831

Orphan

Consensus_repeat	Method
TTGAGAACTGCTATCACCTTTAACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP031643_1

>merge|CP031643|1|452753-452831|CRISPRCasFinder
TTGAGAACTGCTATCACCTTTAACATGGTTACCCCCTTGAGAGCCATTTCCCCCTTGAGAACTGCTATCGCCTTTAACA

>CP031643|1|1|452753-452831|CRISPRCasFinder
TTGAGAACTGCTATCACCTTTAACA	TGGTTACCCCCTTGAGAGCCATTTCCCCC
TTGAGAACTGCTATCGCCTTTAACA

Protein	Signature genes	Signature genes Name	Protein_function
CP031643.1\|AXO91344.1\|451047_452478_+\|proline--tRNA-ligase	unknown	unknown	gnl\|CDD\|236327
CP031643.1\|AXO91351.1\|461695_463327_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372988
CP031643.1\|AXO91353.1\|464462_467129_-\|cation-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319781
CP031643.1\|AXO91335.1\|444357_444612_+\|hypothetical-protein	unknown	unknown	unknown
CP031643.1\|AXO91336.1\|444692_444836_+\|histidine-kinase	unknown	unknown	unknown
CP031643.1\|AXO91348.1\|459478_460063_+\|TerD-family-protein	unknown	unknown	gnl\|CDD\|376767
CP031643.1\|AXO91340.1\|447117_447510_+\|hypothetical-protein	unknown	unknown	unknown
CP031643.1\|AXO91339.1\|446853_447105_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|224393
CP031643.1\|AXO91354.1\|467320_467545_-\|DUF1128-domain-containing-protein	unknown	unknown	gnl\|CDD\|377674
CP031643.1\|AXO91345.1\|453748_457789_+\|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase	unknown	unknown	gnl\|CDD\|226656
CP031643.1\|AXO91341.1\|447547_448831_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341035
CP031643.1\|AXO91342.1\|448939_450253_-\|alkaline-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|293742
CP031643.1\|AXO91352.1\|463345_464428_+\|toxic-anion-resistance-protein	unknown	unknown	gnl\|CDD\|377557
CP031643.1\|AXO91343.1\|450406_450700_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372929
CP031643.1\|AXO91346.1\|457851_458730_+\|ROK-family-protein	unknown	unknown	gnl\|CDD\|224851
CP031643.1\|AXO91338.1\|445564_446797_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
CP031643.1\|AXO91347.1\|458858_459455_+\|TerD-family-protein	unknown	unknown	gnl\|CDD\|376767
CP031643.1\|AXO91349.1\|460142_460721_+\|TerD-family-protein	unknown	unknown	gnl\|CDD\|376767
CP031643.1\|AXO91350.1\|460794_461586_+\|DUF475-domain-containing-protein	unknown	unknown	gnl\|CDD\|274742
CP031643.1\|AXO91337.1\|444916_445498_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|369830

Protein	Function_ID	Function_description	E-value
CP031643.1\|AXO91344.1\|451047_452478_+\|proline--tRNA-ligase	gnl\|CDD\|236327	PRK08661, PRK08661, prolyl-tRNA synthetase; Provisional.	0
CP031643.1\|AXO91351.1\|461695_463327_+\|hypothetical-protein	gnl\|CDD\|372988	pfam14266, YceG_bac, Putative component of 'biosynthetic module'. YceG is a family of proteins found in bacteria. Proteins in this family are approximately 540 amino acids in length. YceG is an additional gene-product encoded in the Ter operon and might thus be part of a 'biosynthetic module' encoding certain enzymes.	0
CP031643.1\|AXO91353.1\|464462_467129_-\|cation-translocating-P-type-ATPase	gnl\|CDD\|319781	cd02089, P-type_ATPase_Ca_prok, prokaryotic P-type Ca(2+)-ATPase similar to Synechococcus elongatus sp. strain PCC 7942 PacL and Listeria monocytogenes LMCA1. Ca(2+) transport ATPase is a plasma membrane protein which pumps Ca(2+) ion out of the cytoplasm. This prokaryotic subfamily includes the Ca(2+)-ATPase Synechococcus elongatus PacL, Listeria monocytogenes Ca(2+)-ATPase 1 (LMCA1) which has a low Ca(2+) affinity and a high pH optimum (pH about 9) and may remove Ca(2+) from the microorganism in environmental conditions when e.g. stressed by high Ca(2+) and alkaline pH, and the Bacillus subtilis putative P-type Ca(2+)-transport ATPase encoded by the yloB gene, which is expressed during sporulation. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
CP031643.1\|AXO91345.1\|453748_457789_+\|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase	gnl\|CDD\|226656	COG4193, LytD, Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism].	2.46944e-23
CP031643.1\|AXO91343.1\|450406_450700_+\|hypothetical-protein	gnl\|CDD\|372929	pfam14150, YesK, YesK-like protein. The YesK-like protein family includes the B. subtilis YesK protein, which is functionally uncharacterized. Its expression is regulated by the sporulation-specific sigma factor sigma-E. This family of proteins is found in bacteria. Proteins in this family are approximately 100 amino acids in length.	1.62707e-19
CP031643.1\|AXO91348.1\|459478_460063_+\|TerD-family-protein	gnl\|CDD\|376767	pfam02342, TerD, TerD domain. The TerD domain is found in TerD family proteins that include the paralogous TerD, TerA, TerE, TerF and TerZ proteins It is found in a stress response operon with TerB and TerC. TerD has a maximum of two calcium-binding sites depending on the conservation of aspartates. It has various fusions to nuclease domains, RNA binding domains, ubiquitin related domains, and metal binding domains. The ter gene products lie at the centre of membrane-linked metal recognition complexes with regulatory ramifications encompassing phosphorylation-dependent signal transduction, RNA-dependent regulation, biosynthesis of nucleoside-like metabolites and DNA processing linked to novel pathways.	4.87053e-115
CP031643.1\|AXO91339.1\|446853_447105_+\|transcriptional-regulator	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	1.58402e-19
CP031643.1\|AXO91354.1\|467320_467545_-\|DUF1128-domain-containing-protein	gnl\|CDD\|377674	pfam06569, DUF1128, Protein of unknown function (DUF1128). This family consists of several short, hypothetical bacterial proteins of unknown function.	2.58998e-28
CP031643.1\|AXO91341.1\|447547_448831_-\|MFS-transporter	gnl\|CDD\|341035	cd17482, MFS_YxiO_like, Bacillus subtilis YxiO, Listeria monocytogenes BtlA, and similar transporters of the Major Facilitator Superfamily. This family is composed of Bacillus subtilis MFS-type transporter YxiO, and similar proteins including Listeria monocytogenes BtlA. The function of B. subtilis YxiO is still unknown, and L. monocytogenes BtlA is a putative secondary transporter involved in bile tolerance and general stress resistance. This family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.04788e-157
CP031643.1\|AXO91342.1\|448939_450253_-\|alkaline-phosphatase-family-protein	gnl\|CDD\|293742	cd16018, Enpp, Ectonucleotide pyrophosphatase/phosphodiesterase, also called autotaxin. Ecto-nucleotide pyrophosphatases/phosphodiesterases (ENPPs) hydrolyze 5'-phosphodiester bonds in nucleotides and their derivatives, resulting in the release of 5'-nucleotide monophosphates. ENPPs have multiple physiological roles, including nucleotide recycling, modulation of purinergic receptor signaling, regulation of extracellular pyrophosphate levels, stimulation of cell motility, and possible roles in regulation of insulin receptor (IR) signaling and activity of ecto-kinases. The eukaryotic ENPP family contains at least five members that have different tissue distribution and physiological roles.	2.63558e-72
CP031643.1\|AXO91352.1\|463345_464428_+\|toxic-anion-resistance-protein	gnl\|CDD\|377557	pfam05816, TelA, Toxic anion resistance protein (TelA). This family consists of several prokaryotic TelA like proteins. TelA and KlA are associated with tellurite resistance and plasmid fertility inhibition.	2.85417e-112
CP031643.1\|AXO91346.1\|457851_458730_+\|ROK-family-protein	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	6.80328e-66
CP031643.1\|AXO91338.1\|445564_446797_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.00341e-63
CP031643.1\|AXO91347.1\|458858_459455_+\|TerD-family-protein	gnl\|CDD\|376767	pfam02342, TerD, TerD domain. The TerD domain is found in TerD family proteins that include the paralogous TerD, TerA, TerE, TerF and TerZ proteins It is found in a stress response operon with TerB and TerC. TerD has a maximum of two calcium-binding sites depending on the conservation of aspartates. It has various fusions to nuclease domains, RNA binding domains, ubiquitin related domains, and metal binding domains. The ter gene products lie at the centre of membrane-linked metal recognition complexes with regulatory ramifications encompassing phosphorylation-dependent signal transduction, RNA-dependent regulation, biosynthesis of nucleoside-like metabolites and DNA processing linked to novel pathways.	2.89829e-89
CP031643.1\|AXO91349.1\|460142_460721_+\|TerD-family-protein	gnl\|CDD\|376767	pfam02342, TerD, TerD domain. The TerD domain is found in TerD family proteins that include the paralogous TerD, TerA, TerE, TerF and TerZ proteins It is found in a stress response operon with TerB and TerC. TerD has a maximum of two calcium-binding sites depending on the conservation of aspartates. It has various fusions to nuclease domains, RNA binding domains, ubiquitin related domains, and metal binding domains. The ter gene products lie at the centre of membrane-linked metal recognition complexes with regulatory ramifications encompassing phosphorylation-dependent signal transduction, RNA-dependent regulation, biosynthesis of nucleoside-like metabolites and DNA processing linked to novel pathways.	3.65816e-118
CP031643.1\|AXO91350.1\|460794_461586_+\|DUF475-domain-containing-protein	gnl\|CDD\|274742	TIGR03716, R_switched_YkoY, integral membrane protein, YkoY family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family often are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains proteins YceF and YkoY from Bacillus subtilis. A transport function is proposed.	1.18501e-88
CP031643.1\|AXO91337.1\|444916_445498_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|369830	pfam08360, TetR_C_5, QacR-like protein, C-terminal region. This family features the C-terminal region of a number of proteins that bear similarity to the QacR protein, a transcriptional regulator of the TetR family. QacR is able to bind various environmental agents, which include a number of cationic lipophilic compounds, and thus regulate the transcription of QacA, a multidrug efflux pump. The C-terminal region contains the multifaceted, expansive drug-binding pocket, which is composed of several separate, but linked, binding sites.	6.56498e-59

>CP031643.1|AXO91344.1|451047_452478_+|proline--tRNA-ligase
MAKEQVQAITKMEEDFAQWYTDIVKKAELVDYSSVKGCMILRPYGYALWENMQKVMDEKLKATGHENVYMPMFIPESLLQKEKDHVEGFAPEVAWVTHGGDEKLAERLCIRPTSETLFCEHFSKIVQSYNDLPKLYNQWCSVVRWEKTTRPFLRTTEFLWQEGHTIHETAEESQAETLNILNLYASFCEDYLAIPVIKGQKTEKEKFAGAKATYTIESLMHDGKALQTGTSHNFGTNFSEAFDIKFLDRTGKWQYVHQTSWGVSTRMIGGLIMVHSDNNGLVMPPKVAPVQVVIVPIAQHKEGVLAKATELQGHIQKVARVKIDASNKTPGWKFNEYEMKGIPIRLEVGPKDIEKNQVVLVRRDTKEKEFISMDQLEERIPALLEEIHNSLFNKAKVFRDENTYSVTNFEEMKKLADEKQGFIKAMWCGELACEEKLKEEVGVSSRCMPFEQEHLADECVCCSKEAKQMVYWGKAY
>CP031643.1|AXO91343.1|450406_450700_+|hypothetical-protein
MDWLDGFGIFYIIGGITIILVFAISYLLKKRFPDKQFDIIFALSLILLCLASFPVTMMVIGGWEGMGYGFIGFFVLLGTLIGMIAHQLVKISRKSYV
>CP031643.1|AXO91342.1|448939_450253_-|alkaline-phosphatase-family-protein
MDKALTNRVIILSFDCLSALDFPILQKLPHFQSLIKKGTVVEKVEPIYPSVTYPSHSTIVTGNYPNKHGVVSNTLLQPGRQSPDWHWYRKSIKGTTLYDEAHKANLTTAALLWPVTGRANIDYNLPEIFPNRPWQNQVLVSLFSGSPLYQLDLNRRFGHIRNGLSQPELDDFVLASAVHTIQMKKPNVMFVHFTDLDTQRHYHGFESKETIAAIHRHDERLGQIIQALKDSDLYEESTIIALGDHSALSENKAIQLNVLFHQKGLISINSKGKLVDWNAYCQSCDGSAYVYVKDKNDTDTIREIQLLLEELLQNKQNGIEFILHDEDAKECGADGNCLFMLEAREGYYFTENYTGDFIKEITEKDVTPSKKYTFGTHGYSPTKPNYETIFIAAGKGIKSGITIPYMRLIDEGPTIARLLGLHLGETDGSIVEDLLQL
>CP031643.1|AXO91341.1|447547_448831_-|MFS-transporter
MKKMSRQEKSWILYDWANSVYSLVITTALFPIYFKAAAKEAGLSGATSTAYWGYANSFATLLISILAPILGTVADYKGFKKRFFTFFFGLGIVFTSMLAVVPTSQWYLLLGCYMLALVGFAGANIFYDAFLVDVTSEDRMDRISTRGFALGYIGSTIPFIGCIALIILAQKGTIPLSVGIASQISFAITALWWGLFTIPMLKNVEQTHYIERHPKPIAMSFKRLADTFKNIKEYKTVFMFLIAYFFYIDGVDTIITMSTAYGTDLGISATNLLIILFVTQIVACPFALLYGKLSTTFTGKKMLYVGIIIYIIICIYAYFLKTTLDFWILAMLVATSQGGIQALSRSYFAKLVPKESANEFFGFYNIFGKFAAIMGPVLVGVTTQLTGKTNAGVLSIIVLFIIGGFLLTRVPENNTSVTPPNPKTKTL
>CP031643.1|AXO91340.1|447117_447510_+|hypothetical-protein
MGKEKISLFVTILVAIGTLVYALYYWLTELQVNWYALFICSIALHYLFKSSASHSVEGETEENQDLEKHVLKTSANVTYYVLVVFIFGLFFASVGFNRWIDFHNIPLLFALCAAIVVKPAIEFLIVRRYR
>CP031643.1|AXO91339.1|446853_447105_+|transcriptional-regulator
MSQLYTDDVKTILQVRRNGVKNQIYELRTENNISQGALADKCKVSRQTINAIENNKYDPSLALAFRLAEVLGTTVDKLFLYKQ
>CP031643.1|AXO91338.1|445564_446797_+|MFS-transporter
MNALFKNRAFMLVMASDILQQFAIWIRNMALLYFIMERTNNDPVSVSLLSVMEYAPIFIFSFIGGALADRWNPKRTMVAGDVLSVLSIIGIVLLLKLDYWQAIFFATLISAIVGQFSQPSSSRIFKRYVKEEQVANAIAFNQTLQSLFMIFGPVVGSLVYTQLGLFTSLYSLIILFLLSAIALSFLPKWVEQEQVARDSLKNDIKEGWKYVLHTKNLRMITITFTIMGLAVGLTNPLEVFLVIERLGMEKEAVQYLAAADGIGMLIGGIVAAVFASKVNPKKMFVFGMSILAMSFLVEGLSTSFWITSFMRFGTGICLACVNIVIGTLMIQLVPENMVGRVNGTILPLFMGAMLIGTALAGGLKEMTSLVIVFCIAMALILLAIGPVLRMQIKKEDVTNKEELTNSLASK
>CP031643.1|AXO91337.1|444916_445498_+|TetR-family-transcriptional-regulator
MRRSAEEIKKEIAYKAEILFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQHTYDWLEKWNEKEKLYSTSTEKLYALAEYHVEDIQQPISNAIEEFSMSQVVSKETLDEMLALTRESYVMFETLIEAGIQSGEFREDNTRDLMYIVNGLLSGLGVLYYELDYKELKRIYKKAIDVLLKGMAAE
>CP031643.1|AXO91336.1|444692_444836_+|histidine-kinase
MKRESKVKNKGKVMLFLLAAGGVFLVKLGFKIGIIHMIRTWFESTFS
>CP031643.1|AXO91335.1|444357_444612_+|hypothetical-protein
MEFIIFILLFVVVGIIVTAVRSNKKKVNLTKQNNIHNSSNNSSPLFFFAGSDNDSSHDGGSHDCGGSFGGDSGGSCDGGGGGGD
>CP031643.1|AXO91345.1|453748_457789_+|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase
MKQTTKQIITGTFLATATSFISTHAFAESDNLATVNATNLNIREQPTTQGKVIGTVKKGTNVQVLSKEKEWAKISHDGKEGYVTLQFLGFSNGNPNVEQKQQLTINNGQKEEGIVTATRLNVRNSPALGSSMIGYVQKNEKVTVLGKANGWAKISYQGKEGYVSLEFVKLEAGKQEEKPSENITNGTREVGTINATSLRVRSAANTSSSILGNLKNGEKVTVLGKANGWAKISYQGKEGYVSLEFVKLGAGKQEEKPVENIKNGTQEVGTINATSLRVRSAANTSSSILGNLKNGEKVTVLGKANGWAKISYQGKEGYVSLEFVKLGAGKQEEKPVENIKNGTQEVGTINATSLRVRSAANTSSSVLGNLKNGEKVTVLGKANGWAKISYQGKEGYVSLEFVKLGAGKQEEKPVENIKNGTQEVGTINATSLRVRSAANTSSSILGNLKNGEKVTVLGKANGWAKINYQGKEGYVSLEFVKLEAGKQEEKPVENIKNGTQEVGTINATSLRVRSAANTSSSILGNLKNGEKVTVLGKANGWAKISYQGKEGYVSLEFVKLEAGKQEEKPVENIKNGTREVGTINATSLRVRSAANTSSSILGNLKNGEKVTVLGKANGWAKISYQGKEGYVSLEFVKLEAGKQEEKPAENITNGTQEVGTINATSLRVRSAANTNSSILGNLKNGEKVTVLGKANGWAKISYQGKEGYVSLEFVKLEAGKQEEKPAENITNGTQEVGTINATSLRVRSAANTSSSVLGNLKNGEKVTVLGKANGWAKISYQGKEGYVSLEFVKLEAGKQEEKPAENITNGTQEVGTINATSLRVRSAANTSSSVLGNLKNGEKVTVLGKANGWAKINYQGKEGYVSLEFITIGKDSIDPTNPGQVIEERAVVNASLLNVRKGPSTGAAAVGHLKNGETVTIIGKENGWAKIRFNGGEGYVSLQFLKVKQGSSSYEIVTSSQKVQKPNEAEATQIMQNMKEDAYIKSDGKVVNMKQGFVRANGVINIYDITTGKKLTYVKGGADLKFVKAVDDRIHVQIDGMTGYVNINDVTLHPTMTGEKTSYYATKNGKLYHYVYNPENGKHATYQIGNAPKHLKEGERYEAFDKKQIGGQDSYQYFEYMPLRATSTYTGDEIDNFLRKSNAKSPLIGLGKYFVSAAEKYKMNAGYLVSHAILESGWGTSRIAQDKKNLFGFRAVDSDPYNGATGFKTWEEGIDFCAAYIDKHYLNPSGNTYNGGNLGDKAQGMNVMYASDENWGQQIASLMYRIDAMNGSKDLNKYRLGTLTAGSPIFKSMAEGQTGMTSRNIMVAIKKTVNTPQGSYYEIVSDNKEYNSVYVKAGSVNLVNSY
>CP031643.1|AXO91346.1|457851_458730_+|ROK-family-protein
MKKYIAFDIGGTQIKSGIIAKSGILLNHETTLTEAHLGGEQIVQKIISLAVQLMNEHVVSGIGISTAGIVDIHRGIITGGVDHIPRYAGIPIIDRLQAVLKVPISIENDVNCALFGEMWQGVGRDENNCIMLTLGTGIGGAIVINKKLYRGHSFSAGEWGNMLIEGKQFEEVASISGLISLVRKYKGSGNWNGEKIFELYDQKDKEVIHAVRIFFKHLAIGISNLTYIFNPKIIIIGGGITNRGNRFLEEVKEEVRKYLNPEIYSNCEIKIAQNRNHAGMIGSIYHFLHQYK
>CP031643.1|AXO91347.1|458858_459455_+|TerD-family-protein
MPIILEKGQKIDLTKGQPKVAKLQVGLGWDPIGQSGGFLSSLFGSKPNVDCDASVVMLEGDRFLNKNDLVYFGNKLSTCGSIIHSGDNLTGEGAGDDETVFVELHKVPSRINRLVFVVNIYDCVNRRQDFGMIRNAYIRIQNPQTGEELARYNLSDNYAGKTTLIAGEMYRYGSEWKFSAVGEGTQDKNLSEIVSRYQ
>CP031643.1|AXO91348.1|459478_460063_+|TerD-family-protein
MASISLKKGQKVDLTKTNPGLSKVLVGLGWDTNRYDGQADFDLDVSIFLVGANGKVSGAEDFVFYNNPKGANGAVEHLGDNRTGEGEGDDESIKVDLKNVPAHIERICFTITIYDGEGRSQNFGQVSNSFVRILDEEKNAELIRYDLGEDFSIETAVVVGELYRHAGEWKFNAIGSGFQGGLASLCNNFGLDVE
>CP031643.1|AXO91349.1|460142_460721_+|TerD-family-protein
MAIQLQKGQKIDLGKTSPGLTKAVIGLGWDIKSYDGGSDFDLDASAFLLDTNGKCTKETDFIFYNNLQSPCGSVLHTGDNRTGEGEGDDEQLVVDLKKVPADVHKIAITVTIYDAEGRSQNFGQVGNAFVRLANEETNEEVLRFDLGEDFSIETAVVFCELYRHNGQWKFNAVGSGFQGGLGALVRAYGLDA
>CP031643.1|AXO91350.1|460794_461586_+|DUF475-domain-containing-protein
MSILQGILDTYAQFFDLDMWIKVLQDPVSWGLIGTLVVLEGLLSADNALVLAVMVKHLPEEKRKKALFYGLIGAYVFRFIAIGIGMFLIKLAWVKVLGALYLAWLSVKYFIDKRKGNAEEEEAHGMNQNSILFRMFGVFWGTVAMVELMDIAFSVDSVLAAFGVSNEVWILLLGGMLGILMMRGIAGVFLKLLERIPELETTAYILILIIAAKMLLSVIHIEISHTVFFIILVVAFGATFILHYMKNSGQAKEEIAATKEDNK
>CP031643.1|AXO91351.1|461695_463327_+|hypothetical-protein
MFSRFTLQPYALKDESDLKQFETLLEKRPQYELTENEMKFSYIACRILGVPNDVDEYFNELFDYSEAKGIEVLHEQNLNKVIDSEKLRHIQEVFGLHQEAPNGLTVNRLVAHLSGKQLLPKVDNPDLQHYIHTTFISVLKLYEKQHNQSLKTEGFRRFLIDMIKLSENYVAKWFSTINYKKQMPRIIWYGDAQESRIYFLYFLIMLGCDVLYYHPEGKDGFENIDEEARTFVVSHSSRISLDPFPDRRRERVATVAYQASKEIEQVLHHDNSLLYKPWQFRSYTPVARTLKTTYDELFLITKEKAFVRPTFFVENKHIYIPSLFAKISGVSKNDKEYFQRLKAVTSFDNSLLINTFPFTKEQKANFQYHYRDALDRGGKLHPDLIMNSHWWPHKRLPEGLQHGIAEAIIHTCESEMCKPIAKETKQDVALYVFAQLSQIPPNILEQLEKFDYSQDVPKIVIFNNEKSGELTRSDAVLLLFLNQIGVDVFHFNPTGRNDIEPYIEAGAFDSHWLEEVNFDLEFHGSSAYKNLSQTIKGLFRPFL
>CP031643.1|AXO91352.1|463345_464428_+|toxic-anion-resistance-protein
MNNPVVLDSKTELNEQTAQDVRLQLRQDADVQRIYNAVDIKDQLELIELGKEPSMEISRFADQILHTMSLSKIEDSGELLKQLGKIMDRFDSKDFAEEKSGFFSRMFKKADKMIEQIFSKYQTMGREIDKVYVEITKYQDEMKKSIGTLDGLYEQNLKYYLDLEKYVVAGEMLLERLNTELVPMYEERVRNNDQLAGIELESLKNSVEILEQRIDDLEKARMVALLTAPQIRMIQRGNNKLIGKINTAFITTIPIFKNGIIQAVNAKRQKLVADSMAELDRRTNELLKKNAQNIATQSVEVARLSGTSSIKMETLEETWNIISRGMQETQQIEEQNKREREESRKRMATLTENIKKELQG
>CP031643.1|AXO91353.1|464462_467129_-|cation-translocating-P-type-ATPase
MSNWYSKTKDQTLIDLETNEQHGLTEEIVNERLTQYGANELATKQKRSLWQRIFAQINDVLVYVLIIAALISAFVGEWADASIIALVVVLNAVIGVVQESKAEQALEALKKMATPKAIVKRDGELKEIPSEHVVPGDVVMLDAGRYIPCDLRLIETANLKVEESALTGESVPVDKDAIYHPSMQSDEQVPLGDQKNMAFMSTLVTYGRGVGIAVETGMNSQIGKIATLLHEADDDMTPLQKSLAQVGKYLGFVAVAICIVMFLIGFLQGRDTLEMFMTAISLAVAAIPEGLPAIVSIVLAIGVQRMIKQNVIIRKLPAVEALGSVTIICSDKTGTLTQNKMTVTHFYSDNTYDQLENLNVNNDVQRLLLENMMLCNDASYNNESQTGDPTEIALLVAGSTFNMQKDHLEKIHERVNELPFDSDRKMMSTVHTYDESYYSMTKGAIDKLLPLCTHIFKNGKIESLTEDDKNQILEAAGTMSQEALRVLSFAFKQYNSNDVDIDHLEENLIFIGLVGMIDPPRTEVKDSITECKKAGIRTVMITGDHKDTAFAIAKELGIAEDISEIMIGTELDNISDTELASKIDHLHVFARVSPEHKVKIVKALRAKGNIVSMTGDGVNDAPSLKQADVGVAMGITGTDVAKGAADVVLTDDNFSSIVKAVEEGRNIYRNIKKSILFLLSCNFGEIITLFLAILLGWATPLRPIHILWVNLITDTLPALSLGVDPEDPDVMKEKPRHAKESLFSGSVPFLIFNGVVIGLLTLIAFIAGAKFYTGDTNLFPLFPERIDEDALLHAQTMAFVVLSFSQLVHSFNLRSRTKSIFSIGIFTNKYLVFSLLIGVLMQVCIISIPPLANIFGVHALTMRDWGFVLLLSIIPLVVNEIIKLVKKN
>CP031643.1|AXO91354.1|467320_467545_-|DUF1128-domain-containing-protein
MDLSVKSEENVEYMVEAIKEKLRMVNAGAMRAASFNEEMYEDLRDIYEHVMKRETFSISEMQAITEELGTLIKK

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Crispr_ID: CP031643_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031643_3

2790626-2790800

Orphan

Consensus_repeat	Method
ATTTCGGAATGAATGTTCATTCCTCTC	PILER-CR

2 spacers

The CRISPR arrays of CP031643_3

>merge|CP031643|3|2790626-2790800|PILER-CR
ATTTTGAAAACACCTTTTCGGAATGAACGTTCATTCCTCTCGTTCTATTAATTTACTTTTTAGCTCTATTAAACTATGGATTTCGGAATGAATATTCATTCCTTTAATTGTACAGATTGATCATCTCCTGCTTTTCTTTTTCACACCCTCATCGGAATGAATGTTCATTCCTGTC

>CP031643|3|1|2790626-2790800|PILER-CR
ATTTTGAAAACACCTTTTCGGAATGAACGTTCATTCCTCTC	GTTCTATTAATTTACTTTTTAGCTCTATTAAACTATGG
ATTTCGGAATGAATATTCATTCCTTTAATTGTACAGATTGA	TCATCTCCTGCTTTTCTTTTTCACACCCTCATCGGAATGAATGTTCA
TTCCTGTC

Protein	Signature genes	Signature genes Name	Protein_function
CP031643.1\|AXO93587.1\|2791693_2792851_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|226925
CP031643.1\|AXO93578.1\|2776944_2778216_-\|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|236502
CP031643.1\|AXO93586.1\|2790817_2791384_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|292911
CP031643.1\|AXO93589.1\|2794443_2795544_-\|prephenate-dehydrogenase	unknown	unknown	gnl\|CDD\|235824
CP031643.1\|AXO93577.1\|2776066_2776894_+\|polysaccharide-deacetylase	unknown	unknown	gnl\|CDD\|200569
CP031643.1\|AXO93595.1\|2804308_2805388_-\|isochorismatase-family-protein	unknown	unknown	gnl\|CDD\|238496
CP031643.1\|AXO93581.1\|2780934_2781606_+\|TerC-family-protein	unknown	unknown	gnl\|CDD\|163429
CP031643.1\|AXO93583.1\|2784156_2785782_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|237894
CP031643.1\|AXO93592.1\|2798112_2799189_-\|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl\|CDD\|183614
CP031643.1\|AXO93591.1\|2796655_2797828_-\|chorismate-synthase	unknown	unknown	gnl\|CDD\|171518
CP031643.1\|AXO93588.1\|2793137_2794427_-\|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|235037
CP031643.1\|AXO93584.1\|2786160_2787009_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|180682
CP031643.1\|AXO93593.1\|2800020_2803533_-\|DUF4020-domain-containing-protein	unknown	unknown	gnl\|CDD\|238697
CP031643.1\|AXO93590.1\|2795536_2796637_-\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|134568
CP031643.1\|AXO93594.1\|2803683_2804121_+\|DUF2512-family-protein	unknown	unknown	gnl\|CDD\|371204
CP031643.1\|AXO93579.1\|2778240_2778510_-\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99905
CP031643.1\|AXO93582.1\|2781665_2783639_-\|LTA-synthase-family-protein	unknown	unknown	gnl\|CDD\|224287
CP031643.1\|AXO93580.1\|2778523_2780629_-\|PRD-domain-containing-protein	unknown	unknown	gnl\|CDD\|226234
CP031643.1\|AXO93585.1\|2787447_2790564_-\|MMPL-family-transporter	unknown	unknown	gnl\|CDD\|225272
CP031643.1\|AXO93576.1\|2775003_2775687_-\|DNA-alkylation-repair-protein	unknown	unknown	gnl\|CDD\|132880

Protein	Function_ID	Function_description	E-value
CP031643.1\|AXO93587.1\|2791693_2792851_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|226925	COG4552, Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only].	2.49112e-71
CP031643.1\|AXO93578.1\|2776944_2778216_-\|PTS-ascorbate-transporter-subunit-IIC	gnl\|CDD\|236502	PRK09410, ulaA, PTS system ascorbate-specific transporter subunit IIC; Reviewed.	0
CP031643.1\|AXO93586.1\|2790817_2791384_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|292911	pfam16295, TetR_C_10, Tetracycline repressor, C-terminal all-alpha domain.	1.12259e-71
CP031643.1\|AXO93589.1\|2794443_2795544_-\|prephenate-dehydrogenase	gnl\|CDD\|235824	PRK06545, PRK06545, prephenate dehydrogenase; Validated.	7.73707e-161
CP031643.1\|AXO93577.1\|2776066_2776894_+\|polysaccharide-deacetylase	gnl\|CDD\|200569	cd10944, CE4_SmPgdA_like, Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins. This family is represented by a putative polysaccharide deacetylase PgdA from the oral pathogen Streptococcus mutans (SmPgdA) and Bacillus subtilis YheN (BsYheN), which are members of the carbohydrate esterase 4 (CE4) superfamily. SmPgdA is an extracellular metal-dependent polysaccharide deacetylase with a typical CE4 fold, with metal bound to a His-His-Asp triad. It possesses de-N-acetylase activity toward a hexamer of chitooligosaccharide N-acetylglucosamine, but not shorter chitooligosaccharides or a synthetic peptidoglycan tetrasaccharide. SmPgdA plays a role in tuning cell surface properties and in interactions with (salivary) agglutinin, an essential component of the innate immune system, most likely through deacetylation of an as-yet-unidentified polysaccharide. SmPgdA shows significant homology to the catalytic domains of peptidoglycan deacetylases from Streptococcus pneumoniae (SpPgdA) and Listeria monocytogenes (LmPgdA), both of which are involved in the bacterial defense mechanism against human mucosal lysozyme. The Bacillus subtilis genome contains six polysaccharide deacetylase gene homologs: pdaA, pdaB (previously known as ybaN), yheN, yjeA, yxkH and ylxY. The biological function of BsYheN is still unknown. This family also includes many uncharacterized polysaccharide deacetylases mainly found in bacteria.	3.31576e-85
CP031643.1\|AXO93595.1\|2804308_2805388_-\|isochorismatase-family-protein	gnl\|CDD\|238496	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia.	1.45627e-67
CP031643.1\|AXO93581.1\|2780934_2781606_+\|TerC-family-protein	gnl\|CDD\|163429	TIGR03717, R_switched_YjbE, integral membrane protein, YjbE family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family commonly are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains protein YjbE from Bacillus subtilis. A transport function is proposed.	3.60657e-74
CP031643.1\|AXO93583.1\|2784156_2785782_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|237894	PRK15064, PRK15064, ABC transporter ATP-binding protein; Provisional.	0
CP031643.1\|AXO93592.1\|2798112_2799189_-\|3-deoxy-7-phosphoheptulonate-synthase	gnl\|CDD\|183614	PRK12595, PRK12595, bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; Reviewed.	0
CP031643.1\|AXO93591.1\|2796655_2797828_-\|chorismate-synthase	gnl\|CDD\|171518	PRK12463, PRK12463, chorismate synthase; Reviewed.	0
CP031643.1\|AXO93588.1\|2793137_2794427_-\|3-phosphoshikimate-1-carboxyvinyltransferase	gnl\|CDD\|235037	PRK02427, PRK02427, 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	0
CP031643.1\|AXO93584.1\|2786160_2787009_-\|hypothetical-protein	gnl\|CDD\|180682	PRK06761, PRK06761, hypothetical protein; Provisional.	3.61634e-147
CP031643.1\|AXO93593.1\|2800020_2803533_-\|DUF4020-domain-containing-protein	gnl\|CDD\|238697	cd01406, SIR2-like, Sir2-like: Prokaryotic group of uncharacterized Sir2-like proteins which lack certain key catalytic residues and conserved zinc binding cysteines; and are members of the SIR2 superfamily of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation.	2.32737e-56
CP031643.1\|AXO93590.1\|2795536_2796637_-\|histidinol-phosphate-transaminase	gnl\|CDD\|134568	PRK01533, PRK01533, histidinol-phosphate aminotransferase; Validated.	0
CP031643.1\|AXO93594.1\|2803683_2804121_+\|DUF2512-family-protein	gnl\|CDD\|371204	pfam10710, DUF2512, Protein of unknown function (DUF2512). Proteins in this family are predicted to be integral membrane proteins, and many of them are annotated as being YndM protein. They are all found in Firmicutes. The true function is not known.	4.48148e-45
CP031643.1\|AXO93579.1\|2778240_2778510_-\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	6.49571e-34
CP031643.1\|AXO93582.1\|2781665_2783639_-\|LTA-synthase-family-protein	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
CP031643.1\|AXO93580.1\|2778523_2780629_-\|PRD-domain-containing-protein	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	9.36949e-57
CP031643.1\|AXO93585.1\|2787447_2790564_-\|MMPL-family-transporter	gnl\|CDD\|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	1.09005e-77
CP031643.1\|AXO93576.1\|2775003_2775687_-\|DNA-alkylation-repair-protein	gnl\|CDD\|132880	cd06561, AlkD_like, A new structural DNA glycosylase. This domain represents a new and uncharacterized structural superfamily of DNA glycosylases that form an alpha-alpha superhelix fold that are not belong to the identified five structural DNA glycosylase superfamilies (UDG, AAG/MNPG, MutM/Fpg and helix-hairpin-helix). DNA glycosylases removing alkylated base residues have been identified in all organisms investigated and may be universally present in nature. DNA glycosylases catalyze the first step in Base Excision Repair (BER) pathway by cleaving damaged DNA bases within double strand DNA to produce an abasic site. The resulting abasic site is further processed by AP endonuclease, phosphodiesterase, DNA polymerases, and DNA ligase functions to restore the DNA to an undamaged state. All glycosylase examined to date utilize a similar strategy for binding DNA and base flipping despite their structural diversity.	1.7994e-25

>CP031643.1|AXO93585.1|2787447_2790564_-|MMPL-family-transporter
MSKLKNWRSLSFLLWIVITITMIVTMPNMDKLVKEKGHITIPNTEQSSIADKMVKEMNKDGTEKYDIIAVFNSGSKTALTTEQKEEITKTINALQNEKEQLGIKEVVSHLDNKELENQFVSKDNTTILTQISIDKKHGEISKVTNNLHKKVQTKGLKTYLTGSDLVAGDFLKSSQEGVKKTEVISIIFILVVLIIVFRSPVVPIISLLTVGVSYLVSMGAIAHLVDQFNFPFSNFTQVFVVVVLFGVGTDYNILLFTRFKEELSKQENAFLATKETFKSAGKTVLYSGIAVLIGFASLALASFKLYQSTSAVAIGVAVLLLVLTTLNPFFMVLLGKGMFYPVKTFKGHEDSRLWGFFAKNSVARPFVALIIVCVISIPFVLKYSNTLNYNDLFEVDNKYESKMGINVIEEHFPPGFSSPSTLVIQSNKKLDEGTSLQTLDELTDKISKVKGVSEVYAPTRPTGDKIKELYINKQAGELNTGLGDANGGLKEINDGLTDAKNKMGGNDSDGLANVQKLIDGTNEAKNGVSALGTALNQLSNGINDGAQGAQQIESGLTSVNENISVLSYATSQLHAGYTQLEKGLSFYDQYFGSISQAIDGAKKGYEQIEMLMTNFIQTKPELANDPNILQTIGIAKEAQKQLSVLSKELNELATQHKAVMGSFKEANQSLLKVDNGLKEMSNGVTKLQKGAADLKNGLNEGATGSKQIANKSSELQTGLTKINDGQGQLLTGLKDLQEQMGQLQSGLSKSTEGLEKVSNGLGDAQKYLGELNESKSSEKFYIPKEVLEGEDFQKALNTYMSHDRKTAKMTIILDVNPYSKEAMPIIQEINKTINGTLKGTELNNAKIAIGGTTARNVDLKEVTGQDFLRTATIMLIGIAIVLILITRSLLNTIFIIGSLLLAYFASLGISEQISTHILHVDSLSWNVPFFSFIMIVALGVDYSIFVMMRYNELEGDPATKILTASRHIGGVVLSAALILGGTFAALIPSGVLTLIQVASVVGVALLLLAIIVMPILLPALIGLTSKIKNYAKKLSERK
>CP031643.1|AXO93584.1|2786160_2787009_-|hypothetical-protein
MNTKLIIVEGLPGFGKSTAAKLINEILSQNKIEVELFLEGNLNHPADYDGVSCFNKFEFDRLLSRSGDFKEVLLKRVIKKGSNYLLPYRKIKNEFGDQFSDELFNPISKNDIYELPFDKNVELIADKWNDFAEIALEDNKVYIFECCFIQNPLTIGMIKYGEQKEKIINYVMKVAKIIENLNPMLLYVEQDNLELSFRKALKERTPEWSAGFVDYYTNQGYGKEHNHSGVEGAIKVLEARRNLELEIFDMLKMKKEKINNTKYEIDSYRSMLKDKLTIQMVK
>CP031643.1|AXO93583.1|2784156_2785782_-|ATP-binding-cassette-domain-containing-protein
MITVSNVSLRFADRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKILSGEIEPSTGDIHITPGERLAVLKQNHFEYEEFPVLETVIMGHTQLYKVMQEKNAIYMKEDFSDEDGMRAAELEGEFAELNGWEAESEAAILLKGLGIGEDLHDKKLSELTGAEKVKVLLAQALFGKPDILLLDEPTNHLDLKAIQWLENFLMNFENTVIVVSHDRHFLNKVCTHMADLDFGKIQLYVGNYDFWYESSQLALKLTQDANKKKEEKVKELQNFIARFSSNASKAKQATSRKKLLDKITLDDLKPSSRRYPFVGFTPEREVGNDLLTVEGLSKTIDGEKVLDNVYFTLNKGDKVAFIGRNDIAMTTLFKILMGEMEPDSGSFKWGVTTSQSYFPRDNSKYFENSDYNLVEWLRQFSPQDESESFLRGFLGRMLFSGEEVKKNVSVLSGGEKVRCMLSKMMLSGANVITLDDPTNHLDLESITALNNGLIAFKGTILFTSHDHQFVQTIANRIIEVTPNGVIDKEATYDEFLENEELQKQVDAMYKGQ
>CP031643.1|AXO93582.1|2781665_2783639_-|LTA-synthase-family-protein
MKQFLLKSKSVLSNHFGFFLFAVILFWLKTYAAYVTEFNLGISNTIQKFLLFFNPLSSAVLFLGLALFAKGKRSYIWLIVINLLLSILLYANVVYYRFFSDFITFPTLTQTNNFGDLGGSIVALLHLYDPLYFLDTIILIVLVATKFANPKPIRVAKHKLSLVFVAGILLFSVNLGLAESDRPELLTRTFDRNYIVKYLGAYNYTIYDGIQSAKASTERALADGDNMTEVRNYLTSTYASPNPEYFGKGKGMNVIYIHLESFQNFLIDYKLNGQEVTPFLNSFTKDANTLYFDNFFHQTGQGKTSDAEFMLENSMFGLPQGSVFTTKSHNTYQSAPAILGQQGYTSAVFHGNYKTFWNRDDIYKSFGFNKFFDASYYDMNEKDVVNYGLKDKPFFNESIPLLETLKQPFYTKFITLSNHFPYPIDKEEATIEPANTGDSSVDTYFQTARYLDESVKGFIDYLKQSGLYDNSIIVMYGDHYGISDNHNAAMSKVMGKEINSFENAQLQRVPLIVRVPGVKGGVQHQYGGEIDVLPTLLHLLGTDTKNYVQFGSDLLSPDHKQVVAFRNGNFVSPTVTALNGKYYDTTTGKPVEFTDEIKQNEQMVQNSLKYSDQVVNGDLLRFYTPEGFTPIDRSKYNYNNRDKNKTKVKTAPEGEAK
>CP031643.1|AXO93581.1|2780934_2781606_+|TerC-family-protein
MDFLSAEYLSALLAIIVIDLVLAGDNAIVIGLAARRLPKDQQKKVIIWGTIGAIAIRALATLVVVWLLKIPGLLLIGGVLLIWIAYKLIAEGKDHDIKAEEGFWSAIKTIIIADALMGIDNVLAVAGAAHGNFSLVIIGLLVSIPVVVWGSTLILKWVDRYPIIITIGAAVLAYTAAKMIVDEKWFAAFFESNPFIKWAFIIIIIAGVVFFGKTKQKATDGSI
>CP031643.1|AXO93580.1|2778523_2780629_-|PRD-domain-containing-protein
MILDTRSINILQQIIQAEDYVSINQLIDMIQVSKRTLYYDIKKIDDWLQEEGLHSIEYIRHLGYCLNKETKQMIVKKLNECINNQYEYSPKERKIWLILYLLIQEKRILLKDLINLLEVSRNTVLADLKKLKVELNKYNLSLHSFRKEGYQIVGNEQSKRNLLILSLSQIISQNGWEYLISQVNYIMSDMGSETDTLARETLYTIKKILANCEEFLGVQYTDEVLENLSVYMYLFHRRILKGKCVEMEEAEKNVLKDSKQFEAAKYIAKQFERAFVVKFPIDEIYYITTHLLGAKVNYQENVYEKNNMDEIHSIVDCMIKDFQHYACVLFQDFNGLFTDLYLHMKPTFYRVKYGIEIENPLRNTIQENYEEVYFLTKKVIHHFEEYVRKSVSDDEIAYVTMHFGAWMRKEGIVPNPRKTALLVCPNGIGTSRMLQYQLEKLFSNIDILNAISKREYESNTFDVDCIITTTEIEKGNVPVFKVNPILSDSEKAALLRKVNGVLYGENQKDSVDLVMGIIQKYADVVDEKSLKRELIEFMSGPAYFEKEEKYKPMLNELLTREFIHLEDRVDNWKDAIRLAADPLLQNQYILEEYINEMIVNVEKLGPYIVIAPKIAIPHARPEAGVKKLGMSLLQLKESVLFSEKQEHAVNLIIVLAAIDNETHLKALAQLSEMLSDPKNVEMLIHSNSIDEMLKMIAKYSN
>CP031643.1|AXO93579.1|2778240_2778510_-|PTS-sugar-transporter-subunit-IIB
MKKVLVVCGNGLGSSFIVEMNVKKILSELGLQAEVSHTDLASSKSEQADLYLGSKDIICNLEDGNRIVAGLTNILDLNEIREALQKHLM
>CP031643.1|AXO93578.1|2776944_2778216_-|PTS-ascorbate-transporter-subunit-IIC
MFDIIMKDILGQPAILVGLFAMCGLLLQKKNFADTVSGTLKTIMGFVVLGGGATILIGALDVFGKIFDKAFHIKGIIPNNEAVVAIAQQTLGKETALIMVFGMIVNLLIARFTKFKYVFLTGHHTLFMACLISAVFSTTGMKGATLVIAGSIILGSLMVIFPALLQPYVRKITGMDDIAIGHFGSVGYLAAGFVGSKFGNKDKSTEQIKVPKSLSFLRDTSVSMSLTMAVLFFIVAPFAGKEFIETELSNGQNYLVYSFMQAITFAAGVYIILAGVRMLIAEIVPAFKGIADKLVPNAKPALDCPTIFPFAPNAVIIGFLTSFIAGLLSMFILPFIGLSVIVPGLIPHFFTGATAAVFGNATGGRRGAVLGAFVNGLLISFLPAILLPILGGLGFENTTFGDSDFAIVGILISEIVKLVGYIF
>CP031643.1|AXO93577.1|2776066_2776894_+|polysaccharide-deacetylase
MHNGIRMTTLVKRAMLICAGVLFTYEAALGSTHTALASTEDEAKSVQLVSEIQSSLAPKEAPKQYNGQVRKVAYLTFDDGPGKYTAELLDMLKKENAKATFFLIGSNVKAFPDLVKREDAEGHYVGMHSMTHNYKKLYTEGHYVDEMKEDQGLIAGVLGKSPVLTRPSYGSMPGLNEALRNKVVENGLKVWDWTIDSLDWRYNKMPVDAASAKIVENVINGANKPTEVILMHDIHPQSVKAVPSIIKGLKEKGYELEAYSENEHFPLNFWHDNRM
>CP031643.1|AXO93576.1|2775003_2775687_-|DNA-alkylation-repair-protein
MLLEEVMQQLEEYGTEQNRKTYKTHGAKEPLFGVSFANLKLLKKKIKKDHDLAISLWATKNMDAMTFATMILDPKKVTTELLNKWVQEVDYYCLMDVLMTAICTSPIAIERMEEWTNSDDEWIGRAGWSLLANIAIKNKTLQDDFFSPYLEEIKENIHNEKNRKREAMNRALIAIGIRNEDLEQTAIEIAREIGKVQVDHGATSCKTPDAESYIKKARERAEKKKMK
>CP031643.1|AXO93586.1|2790817_2791384_-|TetR-family-transcriptional-regulator
MAKNKQEDIFDAAIQLFAERGYDGTTIPMIAEKAKVGAGTIYRYFENKEALVNSLFTKSVLQLSELIKTDFPVNANIREQFSHTYNRLFEFARQNADAFLFTNSHCDSYFLDEHSNEIFEDFMGFFMDLIEDGIEKGFLRPLPPIALIIIVYQPIEKLIKVMETGQLEYTEELVKELEESCWNAIRII
>CP031643.1|AXO93587.1|2791693_2792851_-|GNAT-family-N-acetyltransferase
MNVIRLKEDKFREALRLSEYAFQYKVDEDRLQQQITKMKESHEVYGIMEGENLAAKLHLIPFHIYIGKEKFKMGGVAGVATYPEYRRSGYVKELLQHSLQTMKKDGYTVSMLHPFAVSFYRKYGWELCANLLVCHMTKSDLVMTKQVNGTVKRFNKENHPEEVEKLYETFAERFSGMLVRNEKWWLQAVYDDLTLAIYYDENKTAAGYMLYKIEKSKMTVEEFVPLHNEARNGLWNFICQHDSMIKELEMTVSENEQLLYTLQEPRVKTEIKPYFMGRIVDVEQFLKQYELNWNNVQQEVILHITDSFAQWNNITVRLANHEITIIEEPMDKGIKLDINALSTILFGYRRPLELNELELISGSEEEIRAFENVVPVRKPFIYDFF
>CP031643.1|AXO93588.1|2793137_2794427_-|3-phosphoshikimate-1-carboxyvinyltransferase
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGAIAEGKTTIKGFLPGADCLSTISCFKEMGVDIVQNGDEVTVVGKGLEGLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDASIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAIEYTSPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAFFLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPVIALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCIAEGKTIIEDAEAVGVSYPTFFEELQKLAK
>CP031643.1|AXO93589.1|2794443_2795544_-|prephenate-dehydrogenase
MCKKVVLIGTGLIGGSLALAIKKEHDVTITGYDIFQEQVERAKKLHIVDEIAVDLQHACEEAHLIVFASPVEETKKLLHKLASFHLREDVIVTDVGSTKGSIMNEAEALFSKEISFIGGHPMAGSHKTGVESAKAHLFENAFYILTPMHHVPNEHVEELKDWLKGTGSHFLVLNTEEHDYVTGIVSHFPHLIAAGLVKQVEKHAGDNPLIHQLAAGGFKDITRIASSSPKMWSDIVKQNREHLMVLLKEWISEMEDLYDTVSSGDAGEIQNYFADAKEYRDSLPVRKRGAIPAYHDLYVDVLDKVGALAHITSILAREEISITNLQILEAREGLLGVLRISFQREEDRMKAKLALGEEKYQTYETI
>CP031643.1|AXO93590.1|2795536_2796637_-|histidinol-phosphate-transaminase
MQVKDQLSSLQPYKPGKSPEQMKEVYGDHSFVKLASNENPFGCSPRVLDELQKSWLDHALYPDGGATTLRQTIANKLHVQMEQVLCGSGLDEVIQIISRAVLKAGDNIVTAGATFPQYRHHAIIEGCEVKEVALNNGVYDLDEISSVVDNNTKIVWICNPNNPTGTYVNDRKLTQFIEGISENTLIVIDEAYYEYVTAKDFPETLPLLEKHKNILVLRTFSKAYGLASFRVGYAVGHEELIEKLNVVRLPFNVSSLAQKAATIAFGDDEFIEEIVRVNTEGLRQYESFCKENEIPFYQSQTNFIFLPVENGGEIYEACAHAGFIIRPFPNGVRITVGTREQNEGVISVLQQHFENKKRKSRDEANV
>CP031643.1|AXO93591.1|2796655_2797828_-|chorismate-synthase
MRYITAGESHGPQLTVILEGVPAGLTLTAEHINKELLRRQKGHGRGRRMQIETDTVEIVSGVRHGMTLGSPITLIVKNDDFKHWTKVMGAEPISEKESKEMKRTITKPRPGHADLNGAIKYGHRDIRNVLERSSARETTVRVAAGAVAKQILKELGVEIAGHVLEIGGVKAKHISNLSIEEIQTITENSPVRCLDKTVEQEMMDAIDNAKSSGDSIGGIVEVIAEGMPIGVGSYVHYDRKLDAKLAGAIMSINAFKGAEIGVGFEAARQPGSKVHDEILWDEEQGYTRKTNNAGGLEGGMTTGMPIVVRGVMKPIPTLYKPLASVDIDTKEAFQASIERSDSCAVPAAGVVAESVVAWELAHALVEQFGKDRMELIQQNITQHNKYAKEF
>CP031643.1|AXO93592.1|2798112_2799189_-|3-deoxy-7-phosphoheptulonate-synthase
MANHELDQLRKQVDEINLQLLHLLNKRGEIVQKIGEQKQVQGTKRFDPVREREVLDMIAENNEGPFETSTVQHIFKTIFKASLELQEDDNRKALLVSRKKKQENTIVDVKGELIGNGKQTFIMGPCAVESLEQVRQVGQAMKDQGLKLMRGGAFKPRTSPYDFQGLGVEGLQILRQVADEFDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDEFINAAEYIIAQGNDQIILCERGIRTYERATRNTLDISAVPILKKETHLPVVVDVTHSTGRRDLLLPTAKAALAIGADAVMAEVHPDPAVALSDSAQQMDIPEFHRFMEELKGFKNKLS
>CP031643.1|AXO93593.1|2800020_2803533_-|DUF4020-domain-containing-protein
MTFLGKGESWVWITSEVEIPDELIDHLEQGKLVLFVGAGVSMKGKSNLPNFDDLVDEIAKTLYVEKREITEPHDYYLGKIAKSKDVHQVARDLVHIEKSKPNPLHYAIPRLFPLDTEVRIVTTNFDRHFTTAIKEMNRELNVYYAPALPTGRAFKGLAYIHGNIEQEKEALILTDGDFGRAYLTEGWARRFLVDLFSNYTVLFIGYSHNDPVMKYLATGLPPSTRRYAFVAQGENTYHWEHLGIRPIVYPNKGNNHQSLVKAVKRWAELMGDNYITKRMRIRDIVTVPPSVEQEQLSYIKQSIKKIETVRYFVEFAHDYEWVEWLEAEGKLKNLFLITSNYNEVDELLAKWLVEQFLFSHQKELFQLIFKNHSKLSPLLWRTICSYLNETKMKMDPLLFARWTLLLLETAEKDSKSIETISYLLQKCSFPEHKEIALLLLTFILDGKLKLKRERKWGNDTGESIELEESSRLPVSTFSFVEQIWNEKMKPHISYYAVPIMMMGIEKMRMLSLRQAALKKRDKENVEKEFQQNDLAFLIQIVKECLAYLCKNNEKKANYYITEMIEANSVLQNRIAIDAMNKNVFVSADEKMKWLLQEGILLDVTYKHEVFQLIKNHFALSLEKTKEEVIQIVLKDLVEGRAFDVCFVLDLLFTCDSNSPSTAKAYELMKQKHPHFHSERFSVQKKEAAEQSITCNVTADGLLQLKDDEIMKQVQQFSQDGVFEQRHFLEMLSKACKLNTEWSISFAYQLVGMHEISNEVWFVCIREWRNNRGLTNEQIQKVIPLLQKFVRNTAFHWLISSFLYEISNRLEELEENSIRNVKRFAFSVFPQVMKSDTDFKLAKQDFYNESIQHPVGKMTAVLLKLLSYDHLYDRNVYEYLFLFEEQIRISTERTNFMIARLVADITFLYHIEKQWCRKYLLPYLELKKENEITKYAWAGLCYTQINLPLFTEMKRFIKYAVEHLEVLHPHTREAFLKWLSFVFIKCVLYWEQKTDWLYPLLIRENEENKIKFMQFLCYYVKTLSTKEQQKFWAAWLSIFLRERPKMGGITAREYVMLLRIILFMDEIVERGLLIICKSFSDVGGKGNQTELKQLFHEILEKTESIKMYKELYANVFFTLLQTLQEANLLETEIIQIKELLIGYRVEKCVINAIDNEIIRIGIVLENLQEEM
>CP031643.1|AXO93594.1|2803683_2804121_+|DUF2512-family-protein
MNDFTVVLIKFISCIIAFSIGLALFFPATFVQIISFSLFVTIVSYMFVDKIILNRIGNTGAIMSDFLLTYLSVWIFGNILLDNYMQIAWGSFLSAIVFTLSEVIVHRFSGSHTRHHNDNIRINRRFAYGTEFAEEQNILDKDKKK
>CP031643.1|AXO93595.1|2804308_2805388_-|isochorismatase-family-protein
MLFQKDNVSVRYVVEEDAPIISKWLTDPEVLQYYEGRDNPQSVEMVLNHFIHNPNSHEKRCLIEFDDVPIGYIQMYPVDSEWKTLYGYEASQNVWGMDQFIGEPAYWEKGIGTKLVQSAITYIMENMGAEAIAMDPKVNNERAIKCYEKCGFKKVKILKEHELHEGVLEDCWMMEYKPRELRDMKKALLVIDVQAGMYTAGMTVHNGEKFLEILQELIGECRSNDIPVIYVQHNGPKDHPLEKGTDGWKVHEAIAPLEGDCVVEKTTPDSFHKTNLKEVLQDKGIDHVIISGMQTQYCVDTTTRRACSEGYKVTLVSDAHSTFDTEVLRAEDIVKHHNVVFGAFADVIPLKDLKVTASK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

333021 : 341397

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXO91238.1\|333021_334329_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	8.3e-21	25.5
AXO91239.1\|334417_335137_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	1.2e-48	44.3
AXO91240.1\|335129_335384_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AXO91241.1\|335380_336064_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AXO91242.1\|336047_338267_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.7e-162	41.2
AXO91243.1\|338251_339667_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	7.3e-55	35.4
AXO91244.1\|339772_340813_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	9.4e-68	46.4
AXO91245.1\|340809_341397_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.0e-27	36.6

DBSCAN-SWA_2

1835852 : 1844056

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXO92653.1\|1835852_1837115_+	peptidoglycan endopeptidase	A0A1V0DZX6	Clostridioides_phage	8.9e-12	32.0
AXO92654.1\|1837213_1837978_-	alpha/beta hydrolase	NA	NA	NA	NA
AXO92655.1\|1838218_1839979_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.2e-268	95.9
AXO96068.1\|1840058_1840745_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	5.0e-118	93.4
AXO92656.1\|1840741_1841812_+	sensor histidine kinase	W8CYF6	Bacillus_phage	7.0e-167	87.3
AXO92657.1\|1841929_1843342_-	sensor histidine kinase	A0A1V0SGX0	Hokovirus	2.1e-09	25.6
AXO92658.1\|1843342_1844056_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	5.0e-36	39.0

DBSCAN-SWA_3

1979784 : 2023396

Bacillus_phage(80.0%)

tail,terminase,holin,integrase,protease,capsid,head,portal

attL 2011096:2011112|attR 2023571:2023587

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXO92803.1\|1979784_1980954_+	DEAD/DEAH box family ATP-dependent RNA helicase	A0A1V0SBR7	Catovirus	2.2e-41	29.6
AXO92804.1\|1981172_1981982_+	sugar phosphate isomerase/epimerase	NA	NA	NA	NA
AXO92805.1\|1982037_1982223_+	lactoylglutathione lyase	NA	NA	NA	NA
AXO92806.1\|1982296_1983406_-\|integrase	site-specific integrase	A0A0U3U8Y8	Bacillus_phage	1.8e-178	98.4
AXO92807.1\|1983856_1984210_-	XRE family transcriptional regulator	A0A1B1P888	Bacillus_phage	1.8e-18	41.8
AXO92808.1\|1984709_1985924_+	hypothetical protein	D2XQ10	Bacillus_virus	8.7e-81	44.6
AXO92809.1\|1986386_1986728_-	XRE family transcriptional regulator	A0A1B0T6A7	Bacillus_phage	6.1e-16	40.9
AXO92810.1\|1986902_1987124_+	XRE family transcriptional regulator	NA	NA	NA	NA
AXO92811.1\|1987142_1987853_+	hypothetical protein	A0A1B1P7T7	Bacillus_phage	5.1e-57	52.9
AXO92812.1\|1987893_1988160_+	DNA-binding protein	A0A0U3ULL9	Bacillus_phage	9.2e-36	89.4
AXO92813.1\|1988534_1989425_+	chromosomal replication initiator DnaA	A0A0U3TZZ4	Bacillus_phage	2.7e-92	66.2
AXO92814.1\|1989439_1990354_+	AAA family ATPase	A0A0U3U1U1	Bacillus_phage	7.0e-168	98.0
AXO92815.1\|1990366_1990561_+	hypothetical protein	A0A1B1P7U7	Bacillus_phage	6.3e-26	85.9
AXO92816.1\|1990586_1990760_+	DUF3954 domain-containing protein	A0A1B1P7U5	Bacillus_phage	1.1e-24	94.7
AXO92817.1\|1990774_1991029_+	hypothetical protein	A0A0U3SU43	Bacillus_phage	1.8e-36	88.1
AXO92818.1\|1991040_1991460_+	hypothetical protein	A0A1B1P8B9	Bacillus_phage	9.1e-14	40.7
AXO96078.1\|1991475_1991970_+	nucleotide pyrophosphohydrolase	A0A0U4IBD0	Bacillus_phage	4.1e-21	50.5
AXO92819.1\|1991997_1992195_+	hypothetical protein	NA	NA	NA	NA
AXO92820.1\|1992229_1992421_+	hypothetical protein	NA	NA	NA	NA
AXO92821.1\|1992440_1992986_+	hypothetical protein	A0A2I6UHP6	Bacillus_phage	1.8e-38	48.4
AXO92822.1\|1993347_1993620_-	hypothetical protein	NA	NA	NA	NA
AXO92823.1\|1993947_1994211_+	hypothetical protein	A0A0U3K3K8	Bacillus_phage	1.7e-37	95.4
AXO92824.1\|1994146_1994329_+	hypothetical protein	NA	NA	NA	NA
AXO92825.1\|1994306_1994486_+	hypothetical protein	A0A0S2MVH2	Bacillus_phage	2.3e-22	83.1
AXO92826.1\|1994515_1994845_+	permease	NA	NA	NA	NA
AXO92827.1\|1994862_1994985_+	DUF3983 domain-containing protein	NA	NA	NA	NA
AXO92828.1\|1995298_1995781_+	ArpU family transcriptional regulator	H0USV3	Bacillus_phage	1.2e-73	84.4
AXO92829.1\|1995780_1996323_+\|integrase	site-specific integrase	W8CYP1	Bacillus_phage	1.9e-88	91.7
AXO92830.1\|1996563_1997295_+	hypothetical protein	Q0H269	Geobacillus_phage	8.3e-71	51.9
AXO92831.1\|1997297_1998047_+	DUF4065 domain-containing protein	Q0H268	Geobacillus_phage	1.5e-99	69.8
AXO92832.1\|1998494_1998755_+	hypothetical protein	A0A1B1P7Q2	Bacillus_phage	3.5e-16	62.7
AXO92833.1\|1998738_1999029_+	hypothetical protein	NA	NA	NA	NA
AXO92834.1\|1999035_1999290_+	hypothetical protein	H0USW0	Bacillus_phage	5.9e-40	91.7
AXO92835.1\|1999279_1999657_+	HNH endonuclease	A0A2H4J3B4	uncultured_Caudovirales_phage	1.6e-65	93.6
AXO92836.1\|1999786_2000290_+\|terminase	phage terminase small subunit P27 family	A0A2H4J8E3	uncultured_Caudovirales_phage	3.0e-88	99.4
AXO92837.1\|2000291_2001986_+\|terminase	terminase large subunit	H0USW3	Bacillus_phage	6.2e-312	97.9
AXO92838.1\|2002174_2003428_+\|portal	phage portal protein	A0A2H4J371	uncultured_Caudovirales_phage	2.2e-236	97.4
AXO92839.1\|2003414_2004125_+\|protease	Clp protease ClpP	W8CYT5	Bacillus_phage	6.3e-124	94.9
AXO92840.1\|2004162_2005335_+\|capsid	phage major capsid protein	A0A2H4J387	uncultured_Caudovirales_phage	1.4e-197	92.6
AXO92841.1\|2005355_2005643_+\|head,tail	phage gp6-like head-tail connector protein	H0USW7	Bacillus_phage	6.8e-45	98.9
AXO92842.1\|2005629_2005953_+\|head,tail	head-tail adaptor protein	H0USW8	Bacillus_phage	2.4e-54	94.4
AXO92843.1\|2005945_2006380_+	HK97 gp10 family phage protein	H0USW9	Bacillus_phage	3.1e-73	94.4
AXO92844.1\|2006376_2006736_+	DUF3168 domain-containing protein	H0USX0	Bacillus_phage	1.1e-60	98.3
AXO92845.1\|2006736_2007342_+\|tail	phage tail protein	A0A0S2GLI0	Bacillus_phage	4.0e-95	91.0
AXO92846.1\|2007391_2007709_+	hypothetical protein	W8CYN3	Bacillus_phage	6.6e-49	91.4
AXO92847.1\|2007924_2011743_+\|tail	phage tail tape measure protein	Q2I8F0	Bacillus_phage	0.0e+00	92.0
2011096:2011112	attL	NA	NA	NA	NA
AXO96079.1\|2011817_2012531_+\|tail	phage tail family protein	A0A2H4JBY6	uncultured_Caudovirales_phage	4.9e-60	49.8
AXO92848.1\|2012546_2014637_+	hypothetical protein	A0A0U4JID8	Exiguobacterium_phage	1.1e-80	33.3
AXO92849.1\|2014648_2014858_+	hypothetical protein	NA	NA	NA	NA
AXO92850.1\|2014826_2016023_+	DUF2479 domain-containing protein	A0A1B1P768	Bacillus_phage	6.4e-60	38.3
AXO92851.1\|2016037_2016487_+	hypothetical protein	I1TLF7	Bacillus_phage	4.9e-05	40.2
AXO92852.1\|2016758_2017448_+	hypothetical protein	D2XR29	Bacillus_phage	6.6e-102	84.1
AXO92853.1\|2017814_2018774_+\|integrase	site-specific integrase	D2XR30	Bacillus_phage	9.9e-173	94.0
AXO92854.1\|2018789_2019230_+\|holin	holin	A0A1B1P7S2	Bacillus_phage	3.8e-71	92.5
AXO92855.1\|2019229_2020183_+	N-acetylmuramoyl-L-alanine amidase	A0A0S2MVR5	Bacillus_phage	1.2e-90	56.7
AXO92856.1\|2020288_2020618_-	hypothetical protein	A0A0S2GLG3	Bacillus_phage	1.7e-52	97.2
AXO92857.1\|2020688_2020886_-	helix-turn-helix domain-containing protein	A0A288WG80	Bacillus_phage	2.4e-09	50.0
AXO92858.1\|2021049_2021352_+	hypothetical protein	A0A288WG38	Bacillus_phage	5.5e-45	85.9
AXO92859.1\|2021354_2021537_+	hypothetical protein	Q2I8E2	Bacillus_phage	1.6e-23	93.3
AXO92860.1\|2021652_2022834_+	cell division protein FtsK	H0USY1	Bacillus_phage	3.9e-187	81.7
AXO92861.1\|2022775_2023396_+	hypothetical protein	H0USY2	Bacillus_phage	6.1e-99	83.5
2023571:2023587	attR	NA	NA	NA	NA

DBSCAN-SWA_4

3497074 : 3575431

Bacillus_phage(84.0%)

tail,terminase,tRNA,holin,integrase,protease,capsid,head,portal

attL 3513479:3513493|attR 3574149:3574163

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXO94242.1\|3497074_3497440_+\|holin	CidA/LrgA family holin-like protein	NA	NA	NA	NA
AXO94243.1\|3497436_3498114_+	LrgB family protein	NA	NA	NA	NA
AXO94244.1\|3498127_3498541_-	NUDIX hydrolase	NA	NA	NA	NA
AXO94245.1\|3498682_3498883_+	DUF3903 domain-containing protein	NA	NA	NA	NA
AXO94246.1\|3499198_3499954_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
AXO94247.1\|3500052_3500199_-	BC1881 family protein	NA	NA	NA	NA
AXO94248.1\|3502266_3502770_-	hypothetical protein	NA	NA	NA	NA
AXO94249.1\|3502839_3503859_-	NERD domain-containing protein	A0A1L2JY40	Aeribacillus_phage	4.8e-24	27.5
AXO94250.1\|3503977_3505741_-	ABC transporter ATP-binding protein	A0A1V0SD74	Indivirus	3.2e-15	23.2
AXO94251.1\|3505740_3507492_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.8e-47	28.3
AXO94252.1\|3507615_3507837_-	YneF family protein	NA	NA	NA	NA
AXO94253.1\|3507915_3508356_-	sporulation inhibitor of replication protein SirA	NA	NA	NA	NA
AXO94254.1\|3508512_3510513_-	transketolase	NA	NA	NA	NA
AXO94255.1\|3510617_3510845_+	hypothetical protein	NA	NA	NA	NA
AXO94256.1\|3510815_3511619_-	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
AXO94257.1\|3511618_3512413_-	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
AXO94258.1\|3512409_3513183_-	phosphonate ABC transporter ATP-binding protein	W5SAS9	Pithovirus	2.7e-11	27.5
AXO94259.1\|3513266_3514205_-	phosphate/phosphite/phosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
3513479:3513493	attL	NA	NA	NA	NA
AXO94260.1\|3514390_3515974_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
AXO94261.1\|3516013_3516253_-	DUF896 domain-containing protein	NA	NA	NA	NA
AXO94262.1\|3516298_3516955_-	recombinase family protein	NA	NA	NA	NA
AXO96123.1\|3517096_3517717_+	LexA repressor	A0A1B2APZ1	Phage_Wrath	8.2e-19	62.2
AXO94263.1\|3517818_3518622_-	GNAT family acetyltransferase	NA	NA	NA	NA
AXO94264.1\|3518622_3519165_-	DUF1700 domain-containing protein	NA	NA	NA	NA
AXO94265.1\|3519157_3519481_-	PadR family transcriptional regulator	NA	NA	NA	NA
AXO94266.1\|3520165_3520762_+	hypothetical protein	A0A0U3TZ58	Bacillus_phage	2.7e-88	91.2
AXO94267.1\|3520794_3521418_-	hypothetical protein	H0USY2	Bacillus_phage	1.4e-98	82.9
AXO94268.1\|3521359_3522541_-	cell division protein FtsK	H0USY1	Bacillus_phage	6.5e-190	82.2
AXO94269.1\|3522656_3522839_-	hypothetical protein	Q2I8E2	Bacillus_phage	4.4e-21	86.7
AXO94270.1\|3522841_3523144_-	hypothetical protein	A0A288WG38	Bacillus_phage	5.0e-46	88.9
AXO94271.1\|3523283_3523487_+	helix-turn-helix domain-containing protein	A0A1B1P7S8	Bacillus_phage	5.0e-10	54.4
AXO94272.1\|3523701_3524211_+	protein phosphatase 2C	NA	NA	NA	NA
AXO94273.1\|3524486_3524984_+	protein phosphatase 2C	NA	NA	NA	NA
AXO94274.1\|3525123_3525615_+	protein phosphatase 2C	NA	NA	NA	NA
AXO94275.1\|3525666_3526731_-	N-acetylmuramoyl-L-alanine amidase	A0A1B1P878	Bacillus_phage	4.4e-198	95.2
AXO94276.1\|3526727_3526931_-	hypothetical protein	A0A1B1P886	Bacillus_phage	1.2e-32	97.0
AXO94277.1\|3526932_3527166_-	hypothetical protein	A0A1B1P887	Bacillus_phage	1.7e-30	97.4
AXO94278.1\|3527426_3527858_-	hypothetical protein	A0A1B1P882	Bacillus_phage	1.7e-10	33.6
AXO94279.1\|3527872_3529201_-	DUF2479 domain-containing protein	A0A1C8E978	Bacillus_phage	7.3e-57	34.8
AXO94280.1\|3529127_3529337_-	hypothetical protein	NA	NA	NA	NA
AXO94281.1\|3529348_3531385_-	hypothetical protein	A0A0U4JID8	Exiguobacterium_phage	1.6e-79	33.5
AXO94282.1\|3531400_3532192_-\|tail	phage tail family protein	A0A2H4JBY6	uncultured_Caudovirales_phage	9.0e-71	54.5
AXO94283.1\|3532191_3537219_-\|tail	phage tail tape measure protein	A0A1B1P7S6	Bacillus_phage	0.0e+00	81.7
AXO96124.1\|3537234_3537375_-	LysR family transcriptional regulator	A0A1B1P7R9	Bacillus_phage	1.6e-15	87.0
AXO94284.1\|3537392_3537788_-	hypothetical protein	A0A1B1P7S9	Bacillus_phage	6.5e-46	74.0
AXO94285.1\|3537859_3538429_-\|tail	phage tail protein	A0A1B1P7S4	Bacillus_phage	4.3e-83	77.4
AXO94286.1\|3538440_3538800_-	structural protein	A0A1B1P7S7	Bacillus_phage	8.8e-58	89.9
AXO94287.1\|3538796_3539234_-	HK97 gp10 family phage protein	A0A1B1P7R6	Bacillus_phage	4.8e-74	96.6
AXO94288.1\|3539221_3539569_-\|head,tail	head-tail adaptor protein	A0A1B1P7T4	Bacillus_phage	6.3e-61	99.1
AXO94289.1\|3539555_3539831_-\|head,tail	phage gp6-like head-tail connector protein	A0A1B1P7Q8	Bacillus_phage	1.6e-38	92.3
AXO94290.1\|3539839_3540139_-	fibronectin type III domain-containing protein	NA	NA	NA	NA
AXO94291.1\|3540116_3541304_-\|capsid	phage major capsid protein	A0A1B1P7R4	Bacillus_phage	6.1e-204	92.9
AXO94292.1\|3541300_3542056_-\|protease	Clp protease ClpP	A0A0U3U021	Bacillus_phage	1.4e-129	94.0
AXO94293.1\|3542033_3543248_-\|portal	phage portal protein	A0A0U3SQF0	Bacillus_phage	8.0e-228	95.5
AXO94294.1\|3543263_3545036_-\|terminase	terminase large subunit	A0A1B1P7R3	Bacillus_phage	0.0e+00	96.4
AXO94295.1\|3545016_3545397_-\|terminase	phage terminase small subunit P27 family	A0A1B1P7R2	Bacillus_phage	2.7e-65	97.6
AXO94296.1\|3545558_3545921_-	HNH endonuclease	A0A1B1P8D2	Bacillus_phage	3.1e-50	80.0
AXO94297.1\|3545913_3546129_-	hypothetical protein	NA	NA	NA	NA
AXO94298.1\|3546204_3546390_-	hypothetical protein	NA	NA	NA	NA
AXO94299.1\|3546565_3548017_+	hypothetical protein	NA	NA	NA	NA
AXO94300.1\|3548290_3548833_-\|integrase	site-specific integrase	A0A1B1P746	Bacillus_phage	4.2e-96	99.4
AXO94301.1\|3548829_3549300_-	ArpU family transcriptional regulator	A0A1B1P744	Bacillus_phage	1.3e-77	93.6
AXO94302.1\|3549606_3549729_-	DUF3983 domain-containing protein	NA	NA	NA	NA
AXO94303.1\|3549746_3549983_-	hypothetical protein	NA	NA	NA	NA
AXO94304.1\|3550015_3550276_-	PadR family transcriptional regulator	NA	NA	NA	NA
AXO94305.1\|3550305_3550722_-	hypothetical protein	A0A1B1P7W5	Bacillus_phage	6.1e-10	33.1
AXO94306.1\|3551863_3552169_-	hypothetical protein	NA	NA	NA	NA
AXO94307.1\|3552198_3552732_-	hypothetical protein	U5PUK4	Bacillus_phage	1.3e-57	63.8
AXO96125.1\|3553131_3553587_-	nucleotide pyrophosphohydrolase	A0A1Q1PVV9	Staphylococcus_phage	5.4e-20	46.6
AXO94308.1\|3553602_3554022_-	hypothetical protein	A0A1B1P8B9	Bacillus_phage	1.2e-16	45.3
AXO94309.1\|3554033_3554288_-	hypothetical protein	A0A0U3SU43	Bacillus_phage	4.5e-40	95.2
AXO94310.1\|3554302_3554476_-	DUF3954 domain-containing protein	A0A1B1P7U5	Bacillus_phage	1.2e-25	100.0
AXO94311.1\|3554501_3554696_-	hypothetical protein	A0A1B1P7U7	Bacillus_phage	1.3e-26	89.1
AXO94312.1\|3554711_3555515_-	AAA family ATPase	A0A1B1P7U2	Bacillus_phage	4.3e-145	98.9
AXO94313.1\|3555483_3556218_-	DnaD domain protein	A0A1B1P7T6	Bacillus_phage	4.6e-93	87.1
AXO94314.1\|3556605_3556866_-	group-specific protein	A0A1B1P7U4	Bacillus_phage	2.9e-34	79.1
AXO94315.1\|3556897_3557629_-	Rha family transcriptional regulator	A0A1B1P7T7	Bacillus_phage	1.5e-125	92.6
AXO94316.1\|3557689_3557899_-	XRE family transcriptional regulator	NA	NA	NA	NA
AXO94317.1\|3558084_3558417_+	XRE family transcriptional regulator	H0UST7	Bacillus_phage	1.2e-19	48.1
AXO94318.1\|3558706_3558856_-	complement C1q protein	NA	NA	NA	NA
AXO94319.1\|3558895_3560044_-	hypothetical protein	A0A0S2MVK2	Bacillus_phage	5.3e-56	35.1
AXO94320.1\|3560515_3560860_+	XRE family transcriptional regulator	A0A1B1P888	Bacillus_phage	1.8e-20	45.5
AXO94321.1\|3561091_3561397_+	hypothetical protein	NA	NA	NA	NA
AXO94322.1\|3561393_3561993_+	hypothetical protein	NA	NA	NA	NA
AXO94323.1\|3562045_3562393_+	hypothetical protein	NA	NA	NA	NA
AXO94324.1\|3562546_3563692_+\|integrase	site-specific integrase	A0A0M5M609	Bacillus_phage	5.7e-66	37.9
AXO94325.1\|3563815_3565150_-	type I glutamate--ammonia ligase	NA	NA	NA	NA
AXO94326.1\|3565198_3565588_-	MerR family transcriptional regulator	NA	NA	NA	NA
AXO94327.1\|3565763_3567035_-	hypothetical protein	NA	NA	NA	NA
AXO94328.1\|3567027_3568302_-	GTPase HflX	NA	NA	NA	NA
AXO94329.1\|3568394_3569018_+	trimeric intracellular cation channel family protein	NA	NA	NA	NA
AXO94330.1\|3569287_3570244_-	stage V sporulation protein K	G3MAX6	Bacillus_virus	6.0e-53	44.0
AXO94331.1\|3570357_3571323_+\|integrase	integrase	NA	NA	NA	NA
AXO94332.1\|3571436_3574151_+	collagen-like protein	NA	NA	NA	NA
AXO94333.1\|3574231_3574456_-	RNA-binding protein Hfq	NA	NA	NA	NA
3574149:3574163	attR	NA	NA	NA	NA
AXO94334.1\|3574477_3575431_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA

DBSCAN-SWA_5

3638035 : 3715198

Bacillus_phage(52.63%)

coat,tail,tRNA,terminase,holin,integrase,protease,capsid,head,portal

attL 3663524:3663539|attR 3704259:3704274

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXO94390.1\|3638035_3638578_-\|coat	outer spore coat protein CotE	NA	NA	NA	NA
AXO94391.1\|3638703_3639135_-	master regulator for biofilm formation	NA	NA	NA	NA
AXO94392.1\|3639138_3640668_-\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
AXO94393.1\|3641096_3641963_-	2-oxoacid:ferredoxin oxidoreductase subunit beta	NA	NA	NA	NA
AXO94394.1\|3641949_3643707_-	2-oxoacid:acceptor oxidoreductase subunit alpha	NA	NA	NA	NA
AXO94395.1\|3643934_3644858_-	membrane dipeptidase	NA	NA	NA	NA
AXO94396.1\|3644917_3645178_-	stage V sporulation protein S	J9PTX7	Bacillus_phage	8.4e-10	43.8
AXO94397.1\|3646285_3647848_-	ribonuclease Y	NA	NA	NA	NA
AXO94398.1\|3648329_3648755_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	2.7e-45	70.5
AXO94399.1\|3649832_3651071_-	competence/damage-inducible protein A	NA	NA	NA	NA
AXO94400.1\|3651091_3651670_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
AXO94401.1\|3651733_3652645_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AXO94402.1\|3652666_3653452_-	DUF3388 domain-containing protein	NA	NA	NA	NA
AXO94403.1\|3653591_3653840_-	DUF3243 domain-containing protein	NA	NA	NA	NA
AXO94404.1\|3653915_3654629_-	SDR family oxidoreductase	NA	NA	NA	NA
AXO94405.1\|3654732_3656019_-	insulinase family protein	A0A2H4UVM3	Bodo_saltans_virus	1.7e-10	28.9
AXO94406.1\|3656019_3657294_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	3.8e-55	29.6
AXO94407.1\|3657492_3658452_-	ABC transporter permease	NA	NA	NA	NA
AXO94408.1\|3658452_3659511_-	ABC transporter permease	NA	NA	NA	NA
AXO94409.1\|3659503_3661036_-	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	3.1e-11	26.6
AXO94410.1\|3661144_3662212_-	BMP family ABC transporter substrate-binding protein	A0A0A7DN02	Lactobacillus_phage	1.1e-50	35.1
AXO94411.1\|3662301_3663027_-	GntR family transcriptional regulator	NA	NA	NA	NA
AXO94412.1\|3663474_3663624_-	cell division protein FtsK	NA	NA	NA	NA
3663524:3663539	attL	NA	NA	NA	NA
AXO94413.1\|3663565_3665947_-	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	2.0e-89	51.4
AXO94414.1\|3666158_3666362_-	ribonuclease	NA	NA	NA	NA
AXO94415.1\|3666358_3667108_-	translocation-enhancing protein TepA	NA	NA	NA	NA
AXO94416.1\|3667211_3668882_-	ribonuclease J	NA	NA	NA	NA
AXO94417.1\|3669386_3669614_+	hypothetical protein	NA	NA	NA	NA
AXO94418.1\|3669648_3670527_-	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
AXO94419.1\|3670538_3671771_-	aspartate kinase	NA	NA	NA	NA
AXO94420.1\|3671794_3672841_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
AXO94421.1\|3672991_3673168_-	dipicolinate synthase	NA	NA	NA	NA
AXO94422.1\|3673384_3673822_+	hypothetical protein	NA	NA	NA	NA
AXO94423.1\|3674249_3675338_-	acyltransferase	NA	NA	NA	NA
AXO94424.1\|3675791_3676751_-	N-acetylmuramoyl-L-alanine amidase	S5M842	Bacillus_phage	8.1e-74	58.7
AXO94425.1\|3676750_3677191_-\|holin	holin	A0A1B1P7S2	Bacillus_phage	2.9e-63	82.9
AXO94426.1\|3677294_3681539_-	hypothetical protein	Q3HL60	Bacillus_phage	1.7e-131	45.9
AXO94427.1\|3681542_3683474_-	hypothetical protein	NA	NA	NA	NA
AXO94428.1\|3683485_3684313_-\|tail	phage tail family protein	NA	NA	NA	NA
AXO94429.1\|3684315_3687927_-	DUF2207 domain-containing protein	A0A2H4JAI2	uncultured_Caudovirales_phage	1.5e-197	91.6
AXO94430.1\|3688158_3688521_-	hypothetical protein	A0A2H4JAG8	uncultured_Caudovirales_phage	2.0e-41	68.3
AXO94431.1\|3688525_3689113_-\|tail	phage tail protein	A0A2H4JDV4	uncultured_Caudovirales_phage	1.6e-85	80.0
AXO94432.1\|3689113_3689449_-	hypothetical protein	D2XR22	Bacillus_phage	1.2e-53	95.4
AXO94433.1\|3689445_3689790_-	HK97 gp10 family phage protein	A0A2H4JAH8	uncultured_Caudovirales_phage	9.1e-52	89.4
AXO94434.1\|3689791_3690145_-\|head,tail	head-tail adaptor protein	A0A2H4JGG7	uncultured_Caudovirales_phage	4.3e-57	93.1
AXO94435.1\|3690146_3690440_-	hypothetical protein	D2XR19	Bacillus_phage	5.0e-43	87.6
AXO94436.1\|3690452_3691616_-\|capsid	phage major capsid protein	A0A2H4JH29	uncultured_Caudovirales_phage	7.8e-188	85.5
AXO94437.1\|3691651_3692407_-\|protease	Clp protease ClpP	A0A2H4JC91	uncultured_Caudovirales_phage	7.4e-131	94.4
AXO96127.1\|3692387_3693497_-\|portal	phage portal protein	A0A2H4JAJ1	uncultured_Caudovirales_phage	7.7e-185	88.0
AXO94438.1\|3693562_3695221_-\|terminase	terminase large subunit	A0A2H4JHE9	uncultured_Caudovirales_phage	1.5e-256	79.0
AXO94439.1\|3695217_3695553_-	hypothetical protein	A0A1B1P762	Bacillus_phage	3.0e-07	31.2
AXO94440.1\|3695704_3696040_-	HNH endonuclease	D2XR61	Bacillus_phage	1.9e-54	92.8
AXO94441.1\|3696005_3696377_-	hypothetical protein	NA	NA	NA	NA
AXO94442.1\|3696571_3697000_+	hypothetical protein	A0A2H4JBE7	uncultured_Caudovirales_phage	1.1e-09	42.5
AXO94443.1\|3699036_3699579_-\|integrase	site-specific integrase	W8CYP1	Bacillus_phage	2.8e-87	90.0
AXO94444.1\|3699578_3700043_-	ArpU family transcriptional regulator	D2XR57	Bacillus_phage	1.3e-72	91.6
AXO94445.1\|3700307_3700691_-	hypothetical protein	NA	NA	NA	NA
AXO94446.1\|3700811_3703778_-	DUF3238 domain-containing protein	A0A2I7SDE4	Paenibacillus_phage	9.7e-25	30.7
AXO94447.1\|3704005_3704197_-	DUF3954 domain-containing protein	D2XR48	Bacillus_phage	9.2e-22	82.5
AXO94448.1\|3704273_3704636_-	cell division protein SepF	D2XR47	Bacillus_phage	2.7e-54	87.5
3704259:3704274	attR	NA	NA	NA	NA
AXO94449.1\|3704610_3704799_-	hypothetical protein	D2XR45	Bacillus_phage	1.3e-15	85.5
AXO94450.1\|3704801_3706124_-	replicative DNA helicase	D2XR44	Bacillus_phage	4.1e-233	93.9
AXO94451.1\|3706120_3707056_-	DnaD domain protein	D2XR43	Bacillus_phage	2.4e-147	88.1
AXO94452.1\|3707335_3707620_-	hypothetical protein	D2XR42	Bacillus_phage	1.1e-23	55.3
AXO94453.1\|3707809_3708034_+	hypothetical protein	Q9T1I9	Lactobacillus_phage	4.0e-16	63.2
AXO94454.1\|3708025_3708235_-	hypothetical protein	NA	NA	NA	NA
AXO94455.1\|3708419_3708641_-	RNA polymerase subunit sigma	NA	NA	NA	NA
AXO94456.1\|3708654_3709242_-	sporulation sigma factor-processing peptidase	D2XR41	Bacillus_phage	2.2e-74	69.7
AXO94457.1\|3709332_3709581_-	hypothetical protein	NA	NA	NA	NA
AXO94458.1\|3709619_3709811_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AXO94459.1\|3709944_3710403_+	XRE family transcriptional regulator	D2XR39	Bacillus_phage	1.6e-24	49.3
AXO94460.1\|3710415_3710850_+	ImmA/IrrE family metallo-endopeptidase	D2XR38	Bacillus_phage	1.8e-60	80.4
AXO94461.1\|3710893_3711619_+	hypothetical protein	NA	NA	NA	NA
AXO96128.1\|3711644_3712286_+	hypothetical protein	NA	NA	NA	NA
AXO94462.1\|3712332_3713328_+	hypothetical protein	NA	NA	NA	NA
AXO94463.1\|3713650_3715198_+	recombinase family protein	I3VYZ3	Thermoanaerobacterium_phage	3.0e-142	52.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP031644

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP031643

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection