CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP012321	Clostridioides difficile strain DSM 28666 chromosome, complete genome	14 crisprs	RT,cas14k,csa3,cas14j,WYL,cas3,DEDDh,DinG,c2c9_V-U4,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	4	56	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP012321_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012321_1

17725-17814

Orphan

Consensus_repeat	Method
TGTGCGTTAGCACTTTAAGCAACAGAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP012321_1

>merge|CP012321|1|17725-17814|CRISPRCasFinder
TGTGCGTTAGCACTTTAAGCAACAGAATAAACTGAACGCATGTGAAGTTTGTTTGTTGGCGCTGTGCGTTAGCACTTTAAGCAACGGAAT

>CP012321|1|1|17725-17814|CRISPRCasFinder
TGTGCGTTAGCACTTTAAGCAACAGAAT	AAACTGAACGCATGTGAAGTTTGTTTGTTGGCGC
TGTGCGTTAGCACTTTAAGCAACGGAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP012321.1\|AXU59226.1\|28404_28626_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU59213.1\|6065_8492_+\|DNA-gyrase-subunit-A	unknown	unknown	gnl\|CDD\|235502
CP012321.1\|AXU59217.1\|9449_9857_+\|serine-protein-kinase	unknown	unknown	gnl\|CDD\|235217
CP012321.1\|AXU59225.1\|27664_28264_+\|recombination-protein	unknown	unknown	gnl\|CDD\|234616
CP012321.1\|AXU59218.1\|9856_10630_+\|RNA-polymerase-sigma-B-factor	unknown	unknown	gnl\|CDD\|274373
CP012321.1\|AXU59210.1\|2804_3011_+\|RNA-binding-mediating-protein	unknown	unknown	gnl\|CDD\|379097
CP012321.1\|AXU59215.1\|8856_9117_+\|membrane-protein	unknown	unknown	unknown
CP012321.1\|AXU59228.1\|39303_39717_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU59216.1\|9128_9446_+\|anti-sigma-B-factor-antagonist	unknown	unknown	gnl\|CDD\|132914
CP012321.1\|AXU59227.1\|28696_29902_-\|glycosyl-transferase	unknown	unknown	gnl\|CDD\|340861
CP012321.1\|AXU59223.1\|25605_27243_+\|DNA-polymerase-III-subunits-gamma/tau	unknown	unknown	gnl\|CDD\|235505
CP012321.1\|AXU59209.1\|1561_2668_+\|DNA-polymerase-III-subunit-beta	unknown	unknown	gnl\|CDD\|235541
CP012321.1\|AXU59221.1\|23087_24359_+\|seryl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|235461
CP012321.1\|AXU59212.1\|4144_6046_+\|DNA-gyrase-subunit-B	unknown	unknown	gnl\|CDD\|235542
CP012321.1\|AXU59211.1\|3028_4144_+\|DNA-replication-and-repair-protein	unknown	unknown	gnl\|CDD\|234608
CP012321.1\|AXU59214.1\|8560_8857_+\|Gas-vesicle-protein	unknown	unknown	gnl\|CDD\|378938
CP012321.1\|AXU59224.1\|27301_27652_+\|DNA-binding-protein,-YbaB/EbfC-family	unknown	unknown	gnl\|CDD\|234669
CP012321.1\|AXU59220.1\|21747_22629_+\|mechanosensitive-ion-channel-protein	unknown	unknown	gnl\|CDD\|182386
CP012321.1\|AXU59222.1\|24679_25135_+\|cytosine/adenosine-deaminase	unknown	unknown	gnl\|CDD\|223663
CP012321.1\|AXU59219.1\|21226_21736_+\|small-molecule-binding-protein	unknown	unknown	gnl\|CDD\|224740

Protein	Function_ID	Function_description	E-value
CP012321.1\|AXU59219.1\|21226_21736_+\|small-molecule-binding-protein	gnl\|CDD\|224740	COG1827, COG1827, Predicted small molecule binding protein (contains 3H domain) [General function prediction only].	7.18512e-44
CP012321.1\|AXU59213.1\|6065_8492_+\|DNA-gyrase-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
CP012321.1\|AXU59217.1\|9449_9857_+\|serine-protein-kinase	gnl\|CDD\|235217	PRK04069, PRK04069, serine-protein kinase RsbW; Provisional.	1.87755e-44
CP012321.1\|AXU59225.1\|27664_28264_+\|recombination-protein	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	6.04881e-129
CP012321.1\|AXU59218.1\|9856_10630_+\|RNA-polymerase-sigma-B-factor	gnl\|CDD\|274373	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily. This group of similar sigma-70 factors includes clades found in Bacilli (including the sporulation factors SigF:TIGR02885 and SigG:TIGR02850 as well as SigB:TIGR02941), and the high GC gram positive bacteria (Actinobacteria) where a variable number of them are found depending on the lineage.	6.4918e-87
CP012321.1\|AXU59210.1\|2804_3011_+\|RNA-binding-mediating-protein	gnl\|CDD\|379097	pfam13275, S4_2, S4 domain. The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4.	5.13778e-28
CP012321.1\|AXU59216.1\|9128_9446_+\|anti-sigma-B-factor-antagonist	gnl\|CDD\|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	1.08798e-25
CP012321.1\|AXU59223.1\|25605_27243_+\|DNA-polymerase-III-subunits-gamma/tau	gnl\|CDD\|235505	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated.	0
CP012321.1\|AXU59209.1\|1561_2668_+\|DNA-polymerase-III-subunit-beta	gnl\|CDD\|235541	PRK05643, PRK05643, DNA polymerase III subunit beta; Validated.	1.36085e-135
CP012321.1\|AXU59221.1\|23087_24359_+\|seryl-tRNA-synthetase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
CP012321.1\|AXU59212.1\|4144_6046_+\|DNA-gyrase-subunit-B	gnl\|CDD\|235542	PRK05644, gyrB, DNA gyrase subunit B; Validated.	0
CP012321.1\|AXU59211.1\|3028_4144_+\|DNA-replication-and-repair-protein	gnl\|CDD\|234608	PRK00064, recF, recombination protein F; Reviewed.	1.43571e-130
CP012321.1\|AXU59214.1\|8560_8857_+\|Gas-vesicle-protein	gnl\|CDD\|378938	pfam12732, YtxH, YtxH-like protein. This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 143 amino acids in length. The N-terminal region is the most conserved. Proteins is this family are functionally uncharacterized.	3.51616e-13
CP012321.1\|AXU59224.1\|27301_27652_+\|DNA-binding-protein,-YbaB/EbfC-family	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	1.04649e-45
CP012321.1\|AXU59227.1\|28696_29902_-\|glycosyl-transferase	gnl\|CDD\|340861	cd17507, GT28_Beta-DGS-like, beta-diglucosyldiacylglycerol synthase and similar proteins. beta-diglucosyldiacylglycerol synthase (processive diacylglycerol beta-glucosyltransferase EC 2.4.1.315) is involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. This family of glycosyltransferases also contains plant major galactolipid synthase (chloroplastic monogalactosyldiacylglycerol synthase 1 EC 2.4.1.46). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	1.60211e-148
CP012321.1\|AXU59222.1\|24679_25135_+\|cytosine/adenosine-deaminase	gnl\|CDD\|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	7.74044e-52
CP012321.1\|AXU59220.1\|21747_22629_+\|mechanosensitive-ion-channel-protein	gnl\|CDD\|182386	PRK10334, PRK10334, small-conductance mechanosensitive channel MscS.	1.72542e-62

>CP012321.1|AXU59218.1|9856_10630_+|RNA-polymerase-sigma-B-factor
MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARLLAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKVWTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQPMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRFFFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL
>CP012321.1|AXU59217.1|9449_9857_+|serine-protein-kinase
MACETIKMEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTNAIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTLMDDVDIESEHNQGTKIKMTKYLGVDI
>CP012321.1|AXU59216.1|9128_9446_+|anti-sigma-B-factor-antagonist
MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNMLDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFKVEG
>CP012321.1|AXU59215.1|8856_9117_+|membrane-protein
MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDYNERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK
>CP012321.1|AXU59214.1|8560_8857_+|Gas-vesicle-protein
MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFNDVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN
>CP012321.1|AXU59213.1|6065_8492_+|DNA-gyrase-subunit-A
MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVHRRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRVLLVDGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPARYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPTAAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIAELVKEKRIEGISDLRDESNRNGVRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLALVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVISLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKINRLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKLNAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKREEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTAMGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNISEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVVSIAKINIEEE
>CP012321.1|AXU59212.1|4144_6046_+|DNA-gyrase-subunit-B
MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVDNSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGKFGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQDKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHYTGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTHEGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEGQTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELTRRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKILNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTLLLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQRYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEENARFVRNLDI
>CP012321.1|AXU59211.1|3028_4144_+|DNA-replication-and-repair-protein
MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIYMLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQKIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQRSRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLSIRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDARLFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQMFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN
>CP012321.1|AXU59210.1|2804_3011_+|RNA-binding-mediating-protein
MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEIELRRGKKIKSGDIVEIEGTKIKVL
>CP012321.1|AXU59209.1|1561_2668_+|DNA-polymerase-III-subunit-beta
MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKLTGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVNSRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLEIVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNEKNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEKNNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEIFIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI
>CP012321.1|AXU59219.1|21226_21736_+|small-molecule-binding-protein
MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALIRARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNHPTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVKELKNNGILS
>CP012321.1|AXU59220.1|21747_22629_+|mechanosensitive-ion-channel-protein
MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVIGIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVAVLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLKTPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKRILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVPSSLLFNNTGNLNTMDKR
>CP012321.1|AXU59221.1|23087_24359_+|seryl-tRNA-synthetase
MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQEVEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLMRIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITGSRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDMFKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLVRQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFKYDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRCLAAILENYQQADGSVVVPEELRPYMGVDVIK
>CP012321.1|AXU59222.1|24679_25135_+|cytosine/adenosine-deaminase
METSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTETLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTRHVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD
>CP012321.1|AXU59223.1|25605_27243_+|DNA-polymerase-III-subunits-gamma/tau
MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCGTRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDDIRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHKIPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALSILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKDIRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILSITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGNNKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEVKSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKDINLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK
>CP012321.1|AXU59224.1|27301_27652_+|DNA-binding-protein,-YbaB/EbfC-family
MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVEASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQMSKVTGGMNIPGLF
>CP012321.1|AXU59225.1|27664_28264_+|recombination-protein
MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEALSKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFKGQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARLVKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI
>CP012321.1|AXU59226.1|28404_28626_+|hypothetical-protein
MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTKKNVRNKNAEFRNNYKNYQYDYEEDFYEPI
>CP012321.1|AXU59227.1|28696_29902_-|glycosyl-transferase
MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDSLKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFKKLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLISVLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKDIVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIEKKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPGQEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIANLILNIISG
>CP012321.1|AXU59228.1|39303_39717_+|hypothetical-protein
MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQLSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKLDEVYGIVKIILAVAYADLGHLKLSDVVKRLSRQVD

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Crispr_ID: CP012321_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012321_2

132941-133025

Orphan

Consensus_repeat	Method
TGTGTGTTAGCACTTTAAGCAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP012321_2

>merge|CP012321|2|132941-133025|CRISPRCasFinder
TGTGTGTTAGCACTTTAAGCAACAGAATAAACTGAACGCATGTGAAGTTTGTTTGTTGGCGCTGTGCGTTAGCACTTTAAGCAAC

>CP012321|2|2|132941-133025|CRISPRCasFinder
TGTGTGTTAGCACTTTAAGCAAC	AGAATAAACTGAACGCATGTGAAGTTTGTTTGTTGGCGC
TGTGCGTTAGCACTTTAAGCAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP012321.1\|AXU59314.1\|124083_125031_+\|DNA-directed-RNA-polymerase-subunit-alpha	unknown	unknown	gnl\|CDD\|235359
CP012321.1\|AXU59317.1\|126333_127200_+\|cobalt-transporter-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|237455
CP012321.1\|AXU59322.1\|130190_130943_+\|germination-specific-N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|274337
CP012321.1\|AXU59329.1\|164128_165208_+\|butyrate-kinase	unknown	unknown	gnl\|CDD\|235099
CP012321.1\|AXU59325.1\|147340_147880_+\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	unknown	unknown	gnl\|CDD\|274161
CP012321.1\|AXU59318.1\|127193_127997_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223692
CP012321.1\|AXU59324.1\|144967_147319_+\|anaerobic-ribonucleoside-triphosphate-reductase	unknown	unknown	gnl\|CDD\|235937
CP012321.1\|AXU59321.1\|129339_129732_+\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
CP012321.1\|AXU59316.1\|125512_126346_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|275313
CP012321.1\|AXU59313.1\|123382_124006_+\|30S-ribosomal-protein-S4	unknown	unknown	gnl\|CDD\|235411
CP012321.1\|AXU59332.1\|166161_167241_+\|2-ketoisovalerate-ferredoxin-reductase	unknown	unknown	gnl\|CDD\|235942
CP012321.1\|AXU59328.1\|163204_164107_+\|phosphate-butyryltransferase	unknown	unknown	gnl\|CDD\|180267
CP012321.1\|AXU59320.1\|128879_129311_+\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
CP012321.1\|AXU59315.1\|125051_125393_+\|50S-ribosomal-protein-L17	unknown	unknown	gnl\|CDD\|235522
CP012321.1\|AXU59319.1\|128028_128760_+\|tRNA-pseudouridine-synthase-1	unknown	unknown	gnl\|CDD\|234577
CP012321.1\|AXU59327.1\|161719_162901_+\|membrane-associated-protein	unknown	unknown	gnl\|CDD\|227193
CP012321.1\|AXU59330.1\|165197_165875_+\|ATP/GTP-binding-protein	unknown	unknown	unknown
CP012321.1\|AXU59323.1\|143410_144595_-\|aspartate-aminotransferase	unknown	unknown	gnl\|CDD\|235596
CP012321.1\|AXU59326.1\|160883_161723_+\|DNA-integrity-scanning-protein-DisA	unknown	unknown	gnl\|CDD\|224539
CP012321.1\|AXU59331.1\|165917_166133_+\|ferredoxin	unknown	unknown	gnl\|CDD\|225131

Protein	Function_ID	Function_description	E-value
CP012321.1\|AXU59314.1\|124083_125031_+\|DNA-directed-RNA-polymerase-subunit-alpha	gnl\|CDD\|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	0
CP012321.1\|AXU59317.1\|126333_127200_+\|cobalt-transporter-ATP-binding-subunit	gnl\|CDD\|237455	PRK13637, cbiO, energy-coupling factor transporter ATPase.	0
CP012321.1\|AXU59322.1\|130190_130943_+\|germination-specific-N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|274337	TIGR02883, spore_cwlD, N-acetylmuramoyl-L-alanine amidase CwlD. Members of this protein family are the CwlD family of N-acetylmuramoyl-L-alanine amidase. This family has been called the germination-specific N-acetylmuramoyl-L-alanine amidase. CwlD is required, along with the putative deactylase PdaA, to make muramic delta-lactam, a novel peptidoglycan constituent found only in spores. CwlD mutants show a germination defect. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Sporulation and germination].	1.1235e-78
CP012321.1\|AXU59329.1\|164128_165208_+\|butyrate-kinase	gnl\|CDD\|235099	PRK03011, PRK03011, butyrate kinase; Provisional.	0
CP012321.1\|AXU59325.1\|147340_147880_+\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	gnl\|CDD\|274161	TIGR02491, Anaerobic_ribonucleoside-triphosphate_reductase, anaerobic ribonucleoside-triphosphate reductase activating protein. This enzyme is a member of the radical-SAM family (pfam04055) and utilizes S-adenosyl methionine, an iron-sulfur cluster and a reductant (dihydroflavodoxin) to produce a glycine-centered radical in the class III (anaerobic) ribonucleotide triphosphate reductase (NrdD, TIGR02487). The two components form an alpha-2/beta-2 heterodimer. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism, Protein fate, Protein modification and repair].	3.78376e-50
CP012321.1\|AXU59318.1\|127193_127997_+\|ABC-transporter-permease	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.3503e-50
CP012321.1\|AXU59324.1\|144967_147319_+\|anaerobic-ribonucleoside-triphosphate-reductase	gnl\|CDD\|235937	PRK07111, PRK07111, anaerobic ribonucleoside triphosphate reductase; Provisional.	0
CP012321.1\|AXU59321.1\|129339_129732_+\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	3.31674e-84
CP012321.1\|AXU59316.1\|125512_126346_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|275313	TIGR04520, ECF_ATPase_1, energy-coupling factor transporter ATPase. Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate].	2.34653e-173
CP012321.1\|AXU59313.1\|123382_124006_+\|30S-ribosomal-protein-S4	gnl\|CDD\|235411	PRK05327, rpsD, 30S ribosomal protein S4; Validated.	1.14224e-119
CP012321.1\|AXU59332.1\|166161_167241_+\|2-ketoisovalerate-ferredoxin-reductase	gnl\|CDD\|235942	PRK07119, PRK07119, 2-ketoisovalerate ferredoxin reductase; Validated.	0
CP012321.1\|AXU59328.1\|163204_164107_+\|phosphate-butyryltransferase	gnl\|CDD\|180267	PRK05805, PRK05805, phosphate butyryltransferase; Validated.	1.26101e-179
CP012321.1\|AXU59320.1\|128879_129311_+\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	1.05591e-98
CP012321.1\|AXU59315.1\|125051_125393_+\|50S-ribosomal-protein-L17	gnl\|CDD\|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	6.12837e-66
CP012321.1\|AXU59319.1\|128028_128760_+\|tRNA-pseudouridine-synthase-1	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	6.63504e-129
CP012321.1\|AXU59327.1\|161719_162901_+\|membrane-associated-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	5.26538e-24
CP012321.1\|AXU59323.1\|143410_144595_-\|aspartate-aminotransferase	gnl\|CDD\|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	2.82682e-180
CP012321.1\|AXU59326.1\|160883_161723_+\|DNA-integrity-scanning-protein-DisA	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	1.4029e-80
CP012321.1\|AXU59331.1\|165917_166133_+\|ferredoxin	gnl\|CDD\|225131	COG2221, DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Energy production and conversion].	6.6539e-10

>CP012321.1|AXU59322.1|130190_130943_+|germination-specific-N-acetylmuramoyl-L-alanine-amidase
MEYYGVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNISEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGLVILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYGAQTFYPKDKQDSKALSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGFLSNEKECKLLTDETYQEKIAWAIYIGIQKYLS
>CP012321.1|AXU59321.1|129339_129732_+|30S-ribosomal-protein-S9
MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETLIRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEGFLTRDARMKERKKYGLKAARRAPQFSKR
>CP012321.1|AXU59320.1|128879_129311_+|50S-ribosomal-protein-L13
MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTFTPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVISHAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK
>CP012321.1|AXU59319.1|128028_128760_+|tRNA-pseudouridine-synthase-1
MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETSLIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSRYSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSGSSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDIIQSKTRSRCGHTAPAQGLFLKKVHY
>CP012321.1|AXU59318.1|127193_127997_+|ABC-transporter-permease
MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWPYIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAITKQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMMTIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADELAMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI
>CP012321.1|AXU59317.1|126333_127200_+|cobalt-transporter-ATP-binding-subunit
MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGSGKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETIDKDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIAMNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVMNHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQEILKVVRGRGLC
>CP012321.1|AXU59316.1|125512_126346_+|ABC-transporter-ATP-binding-protein
MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNGSGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVEEDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMRPKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKGKKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQL
>CP012321.1|AXU59315.1|125051_125393_+|50S-ribosomal-protein-L17
MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRMAEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKGDAAEMAFIELV
>CP012321.1|AXU59314.1|124083_125031_+|DNA-directed-RNA-polymerase-subunit-alpha
MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRILLSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQGPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVPIGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLVEHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEELANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE
>CP012321.1|AXU59313.1|123382_124006_+|30S-ribosomal-protein-S4
MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHGQGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDNVVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNLVEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK
>CP012321.1|AXU59323.1|143410_144595_-|aspartate-aminotransferase
MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVPNNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSITNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSITDKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIASLSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIAYGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFEYKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKIMA
>CP012321.1|AXU59324.1|144967_147319_+|anaerobic-ribonucleoside-triphosphate-reductase
MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLSEQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNSKTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEHSFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAAIAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNIVYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKTYQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETPIFPILIFKVKEGINLNPKDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPDTEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEELDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLTIGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATGKYKLNFSLMGTPAEGLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGHITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVCGRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR
>CP012321.1|AXU59325.1|147340_147880_+|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein
MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDLCGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGFTFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLKYKKVFLVEQYMKDDLSIAE
>CP012321.1|AXU59326.1|160883_161723_+|DNA-integrity-scanning-protein-DisA
MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTRAEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGRAKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTIIDAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGIGVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGGIFK
>CP012321.1|AXU59327.1|161719_162901_+|membrane-associated-protein
MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVSISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVYLKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSGPRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLKEKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKDDIDKISYIKTKPIDLADLANGEEKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDVDIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEVE
>CP012321.1|AXU59328.1|163204_164107_+|phosphate-butyryltransferase
MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANAILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTSIILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENACTVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNAVSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIILTSRADSEETKLNSIALGVLMAAKA
>CP012321.1|AXU59329.1|164128_165208_+|butyrate-kinase
MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYEKVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVGVLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALNQKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERSGGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLVYEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGEDEMIALAQGGLRVLTGEEEAQVYDN
>CP012321.1|AXU59330.1|165197_165875_+|ATP/GTP-binding-protein
MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLDVVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGGDNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLINNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKLYMREDWM
>CP012321.1|AXU59331.1|165917_166133_+|ferredoxin
MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPATVFEMEKCIGCASCATMCPDVVITVERD
>CP012321.1|AXU59332.1|166161_167241_+|2-ketoisovalerate-ferredoxin-reductase
MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELPKIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVLNVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYYRSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEVLEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKAGLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGMTPTPAEIVEKAKKIIAGELVAGGAR

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Crispr_ID: CP012321_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012321_3

139825-139909

Orphan

Consensus_repeat	Method
TGTGTGTTAGCACTTTAAGCAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP012321_3

>merge|CP012321|3|139825-139909|CRISPRCasFinder
TGTGTGTTAGCACTTTAAGCAACAGAATAAACTGAACGCATGTGAAGTTTGTTTGTTGGCGCTGTGCGTTAGCACTTTAAGCAAC

>CP012321|3|3|139825-139909|CRISPRCasFinder
TGTGTGTTAGCACTTTAAGCAAC	AGAATAAACTGAACGCATGTGAAGTTTGTTTGTTGGCGC
TGTGCGTTAGCACTTTAAGCAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP012321.1\|AXU59314.1\|124083_125031_+\|DNA-directed-RNA-polymerase-subunit-alpha	unknown	unknown	gnl\|CDD\|235359
CP012321.1\|AXU59317.1\|126333_127200_+\|cobalt-transporter-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|237455
CP012321.1\|AXU59322.1\|130190_130943_+\|germination-specific-N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|274337
CP012321.1\|AXU59329.1\|164128_165208_+\|butyrate-kinase	unknown	unknown	gnl\|CDD\|235099
CP012321.1\|AXU59325.1\|147340_147880_+\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	unknown	unknown	gnl\|CDD\|274161
CP012321.1\|AXU59318.1\|127193_127997_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223692
CP012321.1\|AXU59324.1\|144967_147319_+\|anaerobic-ribonucleoside-triphosphate-reductase	unknown	unknown	gnl\|CDD\|235937
CP012321.1\|AXU59321.1\|129339_129732_+\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
CP012321.1\|AXU59316.1\|125512_126346_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|275313
CP012321.1\|AXU59313.1\|123382_124006_+\|30S-ribosomal-protein-S4	unknown	unknown	gnl\|CDD\|235411
CP012321.1\|AXU59332.1\|166161_167241_+\|2-ketoisovalerate-ferredoxin-reductase	unknown	unknown	gnl\|CDD\|235942
CP012321.1\|AXU59328.1\|163204_164107_+\|phosphate-butyryltransferase	unknown	unknown	gnl\|CDD\|180267
CP012321.1\|AXU59320.1\|128879_129311_+\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
CP012321.1\|AXU59315.1\|125051_125393_+\|50S-ribosomal-protein-L17	unknown	unknown	gnl\|CDD\|235522
CP012321.1\|AXU59319.1\|128028_128760_+\|tRNA-pseudouridine-synthase-1	unknown	unknown	gnl\|CDD\|234577
CP012321.1\|AXU59327.1\|161719_162901_+\|membrane-associated-protein	unknown	unknown	gnl\|CDD\|227193
CP012321.1\|AXU59330.1\|165197_165875_+\|ATP/GTP-binding-protein	unknown	unknown	unknown
CP012321.1\|AXU59323.1\|143410_144595_-\|aspartate-aminotransferase	unknown	unknown	gnl\|CDD\|235596
CP012321.1\|AXU59326.1\|160883_161723_+\|DNA-integrity-scanning-protein-DisA	unknown	unknown	gnl\|CDD\|224539
CP012321.1\|AXU59331.1\|165917_166133_+\|ferredoxin	unknown	unknown	gnl\|CDD\|225131

Protein	Function_ID	Function_description	E-value
CP012321.1\|AXU59314.1\|124083_125031_+\|DNA-directed-RNA-polymerase-subunit-alpha	gnl\|CDD\|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	0
CP012321.1\|AXU59317.1\|126333_127200_+\|cobalt-transporter-ATP-binding-subunit	gnl\|CDD\|237455	PRK13637, cbiO, energy-coupling factor transporter ATPase.	0
CP012321.1\|AXU59322.1\|130190_130943_+\|germination-specific-N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|274337	TIGR02883, spore_cwlD, N-acetylmuramoyl-L-alanine amidase CwlD. Members of this protein family are the CwlD family of N-acetylmuramoyl-L-alanine amidase. This family has been called the germination-specific N-acetylmuramoyl-L-alanine amidase. CwlD is required, along with the putative deactylase PdaA, to make muramic delta-lactam, a novel peptidoglycan constituent found only in spores. CwlD mutants show a germination defect. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Sporulation and germination].	1.1235e-78
CP012321.1\|AXU59329.1\|164128_165208_+\|butyrate-kinase	gnl\|CDD\|235099	PRK03011, PRK03011, butyrate kinase; Provisional.	0
CP012321.1\|AXU59325.1\|147340_147880_+\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	gnl\|CDD\|274161	TIGR02491, Anaerobic_ribonucleoside-triphosphate_reductase, anaerobic ribonucleoside-triphosphate reductase activating protein. This enzyme is a member of the radical-SAM family (pfam04055) and utilizes S-adenosyl methionine, an iron-sulfur cluster and a reductant (dihydroflavodoxin) to produce a glycine-centered radical in the class III (anaerobic) ribonucleotide triphosphate reductase (NrdD, TIGR02487). The two components form an alpha-2/beta-2 heterodimer. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism, Protein fate, Protein modification and repair].	3.78376e-50
CP012321.1\|AXU59318.1\|127193_127997_+\|ABC-transporter-permease	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.3503e-50
CP012321.1\|AXU59324.1\|144967_147319_+\|anaerobic-ribonucleoside-triphosphate-reductase	gnl\|CDD\|235937	PRK07111, PRK07111, anaerobic ribonucleoside triphosphate reductase; Provisional.	0
CP012321.1\|AXU59321.1\|129339_129732_+\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	3.31674e-84
CP012321.1\|AXU59316.1\|125512_126346_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|275313	TIGR04520, ECF_ATPase_1, energy-coupling factor transporter ATPase. Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate].	2.34653e-173
CP012321.1\|AXU59313.1\|123382_124006_+\|30S-ribosomal-protein-S4	gnl\|CDD\|235411	PRK05327, rpsD, 30S ribosomal protein S4; Validated.	1.14224e-119
CP012321.1\|AXU59332.1\|166161_167241_+\|2-ketoisovalerate-ferredoxin-reductase	gnl\|CDD\|235942	PRK07119, PRK07119, 2-ketoisovalerate ferredoxin reductase; Validated.	0
CP012321.1\|AXU59328.1\|163204_164107_+\|phosphate-butyryltransferase	gnl\|CDD\|180267	PRK05805, PRK05805, phosphate butyryltransferase; Validated.	1.26101e-179
CP012321.1\|AXU59320.1\|128879_129311_+\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	1.05591e-98
CP012321.1\|AXU59315.1\|125051_125393_+\|50S-ribosomal-protein-L17	gnl\|CDD\|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	6.12837e-66
CP012321.1\|AXU59319.1\|128028_128760_+\|tRNA-pseudouridine-synthase-1	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	6.63504e-129
CP012321.1\|AXU59327.1\|161719_162901_+\|membrane-associated-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	5.26538e-24
CP012321.1\|AXU59323.1\|143410_144595_-\|aspartate-aminotransferase	gnl\|CDD\|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	2.82682e-180
CP012321.1\|AXU59326.1\|160883_161723_+\|DNA-integrity-scanning-protein-DisA	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	1.4029e-80
CP012321.1\|AXU59331.1\|165917_166133_+\|ferredoxin	gnl\|CDD\|225131	COG2221, DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Energy production and conversion].	6.6539e-10

>CP012321.1|AXU59322.1|130190_130943_+|germination-specific-N-acetylmuramoyl-L-alanine-amidase
MEYYGVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNISEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGLVILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYGAQTFYPKDKQDSKALSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGFLSNEKECKLLTDETYQEKIAWAIYIGIQKYLS
>CP012321.1|AXU59321.1|129339_129732_+|30S-ribosomal-protein-S9
MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETLIRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEGFLTRDARMKERKKYGLKAARRAPQFSKR
>CP012321.1|AXU59320.1|128879_129311_+|50S-ribosomal-protein-L13
MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTFTPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVISHAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK
>CP012321.1|AXU59319.1|128028_128760_+|tRNA-pseudouridine-synthase-1
MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETSLIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSRYSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSGSSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDIIQSKTRSRCGHTAPAQGLFLKKVHY
>CP012321.1|AXU59318.1|127193_127997_+|ABC-transporter-permease
MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWPYIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAITKQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMMTIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADELAMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI
>CP012321.1|AXU59317.1|126333_127200_+|cobalt-transporter-ATP-binding-subunit
MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGSGKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETIDKDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIAMNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVMNHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQEILKVVRGRGLC
>CP012321.1|AXU59316.1|125512_126346_+|ABC-transporter-ATP-binding-protein
MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNGSGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVEEDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMRPKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKGKKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQL
>CP012321.1|AXU59315.1|125051_125393_+|50S-ribosomal-protein-L17
MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRMAEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKGDAAEMAFIELV
>CP012321.1|AXU59314.1|124083_125031_+|DNA-directed-RNA-polymerase-subunit-alpha
MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRILLSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQGPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVPIGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLVEHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEELANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE
>CP012321.1|AXU59313.1|123382_124006_+|30S-ribosomal-protein-S4
MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHGQGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDNVVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNLVEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK
>CP012321.1|AXU59323.1|143410_144595_-|aspartate-aminotransferase
MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVPNNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSITNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSITDKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIASLSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIAYGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFEYKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKIMA
>CP012321.1|AXU59324.1|144967_147319_+|anaerobic-ribonucleoside-triphosphate-reductase
MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLSEQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNSKTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEHSFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAAIAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNIVYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKTYQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETPIFPILIFKVKEGINLNPKDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPDTEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEELDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLTIGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATGKYKLNFSLMGTPAEGLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGHITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVCGRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR
>CP012321.1|AXU59325.1|147340_147880_+|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein
MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDLCGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGFTFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLKYKKVFLVEQYMKDDLSIAE
>CP012321.1|AXU59326.1|160883_161723_+|DNA-integrity-scanning-protein-DisA
MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTRAEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGRAKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTIIDAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGIGVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGGIFK
>CP012321.1|AXU59327.1|161719_162901_+|membrane-associated-protein
MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVSISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVYLKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSGPRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLKEKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKDDIDKISYIKTKPIDLADLANGEEKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDVDIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEVE
>CP012321.1|AXU59328.1|163204_164107_+|phosphate-butyryltransferase
MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANAILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTSIILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENACTVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNAVSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIILTSRADSEETKLNSIALGVLMAAKA
>CP012321.1|AXU59329.1|164128_165208_+|butyrate-kinase
MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYEKVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVGVLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALNQKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERSGGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLVYEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGEDEMIALAQGGLRVLTGEEEAQVYDN
>CP012321.1|AXU59330.1|165197_165875_+|ATP/GTP-binding-protein
MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLDVVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGGDNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLINNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKLYMREDWM
>CP012321.1|AXU59331.1|165917_166133_+|ferredoxin
MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPATVFEMEKCIGCASCATMCPDVVITVERD
>CP012321.1|AXU59332.1|166161_167241_+|2-ketoisovalerate-ferredoxin-reductase
MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELPKIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVLNVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYYRSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEVLEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKAGLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGMTPTPAEIVEKAKKIIAGELVAGGAR

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Crispr_ID: CP012321_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012321_4

148361-148439

Orphan

Consensus_repeat	Method
TGTTTATAATGTGGATAATATTTAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP012321_4

>merge|CP012321|4|148361-148439|CRISPRCasFinder
TGTTTATAATGTGGATAATATTTAATGTAATAAGTTAAAGCAATATGAATCAACTGTTTATAATGTGGATAATATTATA

>CP012321|4|4|148361-148439|CRISPRCasFinder
TGTTTATAATGTGGATAATATTTAA	TGTAATAAGTTAAAGCAATATGAATCAAC
TGTTTATAATGTGGATAATATTATA

Protein	Signature genes	Signature genes Name	Protein_function
CP012321.1\|AXU59317.1\|126333_127200_+\|cobalt-transporter-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|237455
CP012321.1\|AXU59322.1\|130190_130943_+\|germination-specific-N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|274337
CP012321.1\|AXU59329.1\|164128_165208_+\|butyrate-kinase	unknown	unknown	gnl\|CDD\|235099
CP012321.1\|AXU59325.1\|147340_147880_+\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	unknown	unknown	gnl\|CDD\|274161
CP012321.1\|AXU59321.1\|129339_129732_+\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
CP012321.1\|AXU59324.1\|144967_147319_+\|anaerobic-ribonucleoside-triphosphate-reductase	unknown	unknown	gnl\|CDD\|235937
CP012321.1\|AXU59318.1\|127193_127997_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223692
CP012321.1\|AXU59316.1\|125512_126346_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|275313
CP012321.1\|AXU59328.1\|163204_164107_+\|phosphate-butyryltransferase	unknown	unknown	gnl\|CDD\|180267
CP012321.1\|AXU59334.1\|167993_168551_+\|subunit-of-oxidoreductase	unknown	unknown	gnl\|CDD\|376567
CP012321.1\|AXU59332.1\|166161_167241_+\|2-ketoisovalerate-ferredoxin-reductase	unknown	unknown	gnl\|CDD\|235942
CP012321.1\|AXU59320.1\|128879_129311_+\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
CP012321.1\|AXU59335.1\|168720_170067_+\|phosphoglucomutase/phosphomannomutase-mutase	unknown	unknown	gnl\|CDD\|237670
CP012321.1\|AXU59333.1\|167240_167993_+\|subunit-of-oxidoreductase	unknown	unknown	gnl\|CDD\|239470
CP012321.1\|AXU59319.1\|128028_128760_+\|tRNA-pseudouridine-synthase-1	unknown	unknown	gnl\|CDD\|234577
CP012321.1\|AXU59327.1\|161719_162901_+\|membrane-associated-protein	unknown	unknown	gnl\|CDD\|227193
CP012321.1\|AXU59330.1\|165197_165875_+\|ATP/GTP-binding-protein	unknown	unknown	unknown
CP012321.1\|AXU59323.1\|143410_144595_-\|aspartate-aminotransferase	unknown	unknown	gnl\|CDD\|235596
CP012321.1\|AXU59326.1\|160883_161723_+\|DNA-integrity-scanning-protein-DisA	unknown	unknown	gnl\|CDD\|224539
CP012321.1\|AXU59331.1\|165917_166133_+\|ferredoxin	unknown	unknown	gnl\|CDD\|225131

Protein	Function_ID	Function_description	E-value
CP012321.1\|AXU59317.1\|126333_127200_+\|cobalt-transporter-ATP-binding-subunit	gnl\|CDD\|237455	PRK13637, cbiO, energy-coupling factor transporter ATPase.	0
CP012321.1\|AXU59322.1\|130190_130943_+\|germination-specific-N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|274337	TIGR02883, spore_cwlD, N-acetylmuramoyl-L-alanine amidase CwlD. Members of this protein family are the CwlD family of N-acetylmuramoyl-L-alanine amidase. This family has been called the germination-specific N-acetylmuramoyl-L-alanine amidase. CwlD is required, along with the putative deactylase PdaA, to make muramic delta-lactam, a novel peptidoglycan constituent found only in spores. CwlD mutants show a germination defect. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Sporulation and germination].	1.1235e-78
CP012321.1\|AXU59329.1\|164128_165208_+\|butyrate-kinase	gnl\|CDD\|235099	PRK03011, PRK03011, butyrate kinase; Provisional.	0
CP012321.1\|AXU59325.1\|147340_147880_+\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	gnl\|CDD\|274161	TIGR02491, Anaerobic_ribonucleoside-triphosphate_reductase, anaerobic ribonucleoside-triphosphate reductase activating protein. This enzyme is a member of the radical-SAM family (pfam04055) and utilizes S-adenosyl methionine, an iron-sulfur cluster and a reductant (dihydroflavodoxin) to produce a glycine-centered radical in the class III (anaerobic) ribonucleotide triphosphate reductase (NrdD, TIGR02487). The two components form an alpha-2/beta-2 heterodimer. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism, Protein fate, Protein modification and repair].	3.78376e-50
CP012321.1\|AXU59321.1\|129339_129732_+\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	3.31674e-84
CP012321.1\|AXU59324.1\|144967_147319_+\|anaerobic-ribonucleoside-triphosphate-reductase	gnl\|CDD\|235937	PRK07111, PRK07111, anaerobic ribonucleoside triphosphate reductase; Provisional.	0
CP012321.1\|AXU59318.1\|127193_127997_+\|ABC-transporter-permease	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.3503e-50
CP012321.1\|AXU59316.1\|125512_126346_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|275313	TIGR04520, ECF_ATPase_1, energy-coupling factor transporter ATPase. Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate].	2.34653e-173
CP012321.1\|AXU59328.1\|163204_164107_+\|phosphate-butyryltransferase	gnl\|CDD\|180267	PRK05805, PRK05805, phosphate butyryltransferase; Validated.	1.26101e-179
CP012321.1\|AXU59334.1\|167993_168551_+\|subunit-of-oxidoreductase	gnl\|CDD\|376567	pfam01558, POR, Pyruvate ferredoxin/flavodoxin oxidoreductase. This family includes a region of the large protein pyruvate-flavodoxin oxidoreductase and the whole pyruvate ferredoxin oxidoreductase gamma subunit protein. It is not known whether the gamma subunit has a catalytic or regulatory role. Pyruvate oxidoreductase (POR) catalyzes the final step in the fermentation of carbohydrates in anaerobic microorganisms. This involves the oxidative decarboxylation of pyruvate with the participation of thiamine followed by the transfer of an acetyl moiety to coenzyme A for the synthesis of acetyl-CoA. The family also includes pyruvate flavodoxin oxidoreductase as encoded by the nifJ gene in cyanobacterium which is required for growth on molecular nitrogen when iron is limited.	1.49735e-43
CP012321.1\|AXU59332.1\|166161_167241_+\|2-ketoisovalerate-ferredoxin-reductase	gnl\|CDD\|235942	PRK07119, PRK07119, 2-ketoisovalerate ferredoxin reductase; Validated.	0
CP012321.1\|AXU59320.1\|128879_129311_+\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	1.05591e-98
CP012321.1\|AXU59335.1\|168720_170067_+\|phosphoglucomutase/phosphomannomutase-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
CP012321.1\|AXU59333.1\|167240_167993_+\|subunit-of-oxidoreductase	gnl\|CDD\|239470	cd03375, TPP_OGFOR, Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR catalyzes the oxidative decarboxylation of 2-oxoglutarate to succinyl-CoA. In the reductive tricarboxylic acid cycle found in the anaerobic autotroph Hydrogenobacter thermophilus, OGFOR catalyzes the reductive carboxylation of succinyl-CoA to produce 2-oxoglutarate. Thauera aromatica OGFOR has been shown to provide reduced ferredoxin to benzoyl-CoA reductase, a key enzyme in the anaerobic metabolism of aromatic compounds. OGFOR is dependent on TPP and a divalent metal cation for activity.	1.15077e-77
CP012321.1\|AXU59319.1\|128028_128760_+\|tRNA-pseudouridine-synthase-1	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	6.63504e-129
CP012321.1\|AXU59327.1\|161719_162901_+\|membrane-associated-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	5.26538e-24
CP012321.1\|AXU59323.1\|143410_144595_-\|aspartate-aminotransferase	gnl\|CDD\|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	2.82682e-180
CP012321.1\|AXU59326.1\|160883_161723_+\|DNA-integrity-scanning-protein-DisA	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	1.4029e-80
CP012321.1\|AXU59331.1\|165917_166133_+\|ferredoxin	gnl\|CDD\|225131	COG2221, DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Energy production and conversion].	6.6539e-10

>CP012321.1|AXU59325.1|147340_147880_+|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein
MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDLCGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGFTFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLKYKKVFLVEQYMKDDLSIAE
>CP012321.1|AXU59324.1|144967_147319_+|anaerobic-ribonucleoside-triphosphate-reductase
MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLSEQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNSKTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEHSFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAAIAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNIVYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKTYQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETPIFPILIFKVKEGINLNPKDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPDTEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEELDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLTIGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATGKYKLNFSLMGTPAEGLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGHITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVCGRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR
>CP012321.1|AXU59323.1|143410_144595_-|aspartate-aminotransferase
MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVPNNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSITNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSITDKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIASLSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIAYGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFEYKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKIMA
>CP012321.1|AXU59322.1|130190_130943_+|germination-specific-N-acetylmuramoyl-L-alanine-amidase
MEYYGVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNISEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGLVILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYGAQTFYPKDKQDSKALSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGFLSNEKECKLLTDETYQEKIAWAIYIGIQKYLS
>CP012321.1|AXU59321.1|129339_129732_+|30S-ribosomal-protein-S9
MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETLIRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEGFLTRDARMKERKKYGLKAARRAPQFSKR
>CP012321.1|AXU59320.1|128879_129311_+|50S-ribosomal-protein-L13
MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTFTPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVISHAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK
>CP012321.1|AXU59319.1|128028_128760_+|tRNA-pseudouridine-synthase-1
MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETSLIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSRYSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSGSSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDIIQSKTRSRCGHTAPAQGLFLKKVHY
>CP012321.1|AXU59318.1|127193_127997_+|ABC-transporter-permease
MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWPYIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAITKQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMMTIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADELAMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI
>CP012321.1|AXU59317.1|126333_127200_+|cobalt-transporter-ATP-binding-subunit
MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGSGKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETIDKDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIAMNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVMNHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQEILKVVRGRGLC
>CP012321.1|AXU59316.1|125512_126346_+|ABC-transporter-ATP-binding-protein
MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNGSGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVEEDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMRPKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKGKKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQL
>CP012321.1|AXU59326.1|160883_161723_+|DNA-integrity-scanning-protein-DisA
MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTRAEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGRAKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTIIDAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGIGVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGGIFK
>CP012321.1|AXU59327.1|161719_162901_+|membrane-associated-protein
MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVSISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVYLKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSGPRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLKEKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKDDIDKISYIKTKPIDLADLANGEEKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDVDIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEVE
>CP012321.1|AXU59328.1|163204_164107_+|phosphate-butyryltransferase
MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANAILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTSIILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENACTVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNAVSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIILTSRADSEETKLNSIALGVLMAAKA
>CP012321.1|AXU59329.1|164128_165208_+|butyrate-kinase
MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYEKVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVGVLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALNQKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERSGGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLVYEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGEDEMIALAQGGLRVLTGEEEAQVYDN
>CP012321.1|AXU59330.1|165197_165875_+|ATP/GTP-binding-protein
MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLDVVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGGDNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLINNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKLYMREDWM
>CP012321.1|AXU59331.1|165917_166133_+|ferredoxin
MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPATVFEMEKCIGCASCATMCPDVVITVERD
>CP012321.1|AXU59332.1|166161_167241_+|2-ketoisovalerate-ferredoxin-reductase
MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELPKIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVLNVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYYRSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEVLEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKAGLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGMTPTPAEIVEKAKKIIAGELVAGGAR
>CP012321.1|AXU59333.1|167240_167993_+|subunit-of-oxidoreductase
MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDAVGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGTAEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRVSEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWGLAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK
>CP012321.1|AXU59334.1|167993_168551_+|subunit-of-oxidoreductase
MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEMRGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKEKVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPRKEKFVPLNREALQKGMDATCSKATN
>CP012321.1|AXU59335.1|168720_170067_+|phosphoglucomutase/phosphomannomutase-mutase
MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVVVGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHNPVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYVDYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGSTHPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLAQDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLDYNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEIKTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS

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Crispr_ID: CP012321_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012321_5

150373-150462

Orphan

Consensus_repeat	Method
TGTGCGTTAGCACTTTAAGCAACAGAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP012321_5

>merge|CP012321|5|150373-150462|CRISPRCasFinder
TGTGCGTTAGCACTTTAAGCAACAGAATAAACTGAACGCATGTGAAGTTTGTTTGTTGGCGCTGTGCGTTAGCACTTTAAGCAACGGAAT

>CP012321|5|5|150373-150462|CRISPRCasFinder
TGTGCGTTAGCACTTTAAGCAACAGAAT	AAACTGAACGCATGTGAAGTTTGTTTGTTGGCGC
TGTGCGTTAGCACTTTAAGCAACGGAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP012321.1\|AXU59317.1\|126333_127200_+\|cobalt-transporter-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|237455
CP012321.1\|AXU59322.1\|130190_130943_+\|germination-specific-N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|274337
CP012321.1\|AXU59329.1\|164128_165208_+\|butyrate-kinase	unknown	unknown	gnl\|CDD\|235099
CP012321.1\|AXU59325.1\|147340_147880_+\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	unknown	unknown	gnl\|CDD\|274161
CP012321.1\|AXU59321.1\|129339_129732_+\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
CP012321.1\|AXU59324.1\|144967_147319_+\|anaerobic-ribonucleoside-triphosphate-reductase	unknown	unknown	gnl\|CDD\|235937
CP012321.1\|AXU59318.1\|127193_127997_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223692
CP012321.1\|AXU59316.1\|125512_126346_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|275313
CP012321.1\|AXU59328.1\|163204_164107_+\|phosphate-butyryltransferase	unknown	unknown	gnl\|CDD\|180267
CP012321.1\|AXU59334.1\|167993_168551_+\|subunit-of-oxidoreductase	unknown	unknown	gnl\|CDD\|376567
CP012321.1\|AXU59332.1\|166161_167241_+\|2-ketoisovalerate-ferredoxin-reductase	unknown	unknown	gnl\|CDD\|235942
CP012321.1\|AXU59320.1\|128879_129311_+\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
CP012321.1\|AXU59335.1\|168720_170067_+\|phosphoglucomutase/phosphomannomutase-mutase	unknown	unknown	gnl\|CDD\|237670
CP012321.1\|AXU59333.1\|167240_167993_+\|subunit-of-oxidoreductase	unknown	unknown	gnl\|CDD\|239470
CP012321.1\|AXU59319.1\|128028_128760_+\|tRNA-pseudouridine-synthase-1	unknown	unknown	gnl\|CDD\|234577
CP012321.1\|AXU59327.1\|161719_162901_+\|membrane-associated-protein	unknown	unknown	gnl\|CDD\|227193
CP012321.1\|AXU59330.1\|165197_165875_+\|ATP/GTP-binding-protein	unknown	unknown	unknown
CP012321.1\|AXU59323.1\|143410_144595_-\|aspartate-aminotransferase	unknown	unknown	gnl\|CDD\|235596
CP012321.1\|AXU59326.1\|160883_161723_+\|DNA-integrity-scanning-protein-DisA	unknown	unknown	gnl\|CDD\|224539
CP012321.1\|AXU59331.1\|165917_166133_+\|ferredoxin	unknown	unknown	gnl\|CDD\|225131

Protein	Function_ID	Function_description	E-value
CP012321.1\|AXU59317.1\|126333_127200_+\|cobalt-transporter-ATP-binding-subunit	gnl\|CDD\|237455	PRK13637, cbiO, energy-coupling factor transporter ATPase.	0
CP012321.1\|AXU59322.1\|130190_130943_+\|germination-specific-N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|274337	TIGR02883, spore_cwlD, N-acetylmuramoyl-L-alanine amidase CwlD. Members of this protein family are the CwlD family of N-acetylmuramoyl-L-alanine amidase. This family has been called the germination-specific N-acetylmuramoyl-L-alanine amidase. CwlD is required, along with the putative deactylase PdaA, to make muramic delta-lactam, a novel peptidoglycan constituent found only in spores. CwlD mutants show a germination defect. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Sporulation and germination].	1.1235e-78
CP012321.1\|AXU59329.1\|164128_165208_+\|butyrate-kinase	gnl\|CDD\|235099	PRK03011, PRK03011, butyrate kinase; Provisional.	0
CP012321.1\|AXU59325.1\|147340_147880_+\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	gnl\|CDD\|274161	TIGR02491, Anaerobic_ribonucleoside-triphosphate_reductase, anaerobic ribonucleoside-triphosphate reductase activating protein. This enzyme is a member of the radical-SAM family (pfam04055) and utilizes S-adenosyl methionine, an iron-sulfur cluster and a reductant (dihydroflavodoxin) to produce a glycine-centered radical in the class III (anaerobic) ribonucleotide triphosphate reductase (NrdD, TIGR02487). The two components form an alpha-2/beta-2 heterodimer. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism, Protein fate, Protein modification and repair].	3.78376e-50
CP012321.1\|AXU59321.1\|129339_129732_+\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	3.31674e-84
CP012321.1\|AXU59324.1\|144967_147319_+\|anaerobic-ribonucleoside-triphosphate-reductase	gnl\|CDD\|235937	PRK07111, PRK07111, anaerobic ribonucleoside triphosphate reductase; Provisional.	0
CP012321.1\|AXU59318.1\|127193_127997_+\|ABC-transporter-permease	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.3503e-50
CP012321.1\|AXU59316.1\|125512_126346_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|275313	TIGR04520, ECF_ATPase_1, energy-coupling factor transporter ATPase. Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate].	2.34653e-173
CP012321.1\|AXU59328.1\|163204_164107_+\|phosphate-butyryltransferase	gnl\|CDD\|180267	PRK05805, PRK05805, phosphate butyryltransferase; Validated.	1.26101e-179
CP012321.1\|AXU59334.1\|167993_168551_+\|subunit-of-oxidoreductase	gnl\|CDD\|376567	pfam01558, POR, Pyruvate ferredoxin/flavodoxin oxidoreductase. This family includes a region of the large protein pyruvate-flavodoxin oxidoreductase and the whole pyruvate ferredoxin oxidoreductase gamma subunit protein. It is not known whether the gamma subunit has a catalytic or regulatory role. Pyruvate oxidoreductase (POR) catalyzes the final step in the fermentation of carbohydrates in anaerobic microorganisms. This involves the oxidative decarboxylation of pyruvate with the participation of thiamine followed by the transfer of an acetyl moiety to coenzyme A for the synthesis of acetyl-CoA. The family also includes pyruvate flavodoxin oxidoreductase as encoded by the nifJ gene in cyanobacterium which is required for growth on molecular nitrogen when iron is limited.	1.49735e-43
CP012321.1\|AXU59332.1\|166161_167241_+\|2-ketoisovalerate-ferredoxin-reductase	gnl\|CDD\|235942	PRK07119, PRK07119, 2-ketoisovalerate ferredoxin reductase; Validated.	0
CP012321.1\|AXU59320.1\|128879_129311_+\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	1.05591e-98
CP012321.1\|AXU59335.1\|168720_170067_+\|phosphoglucomutase/phosphomannomutase-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
CP012321.1\|AXU59333.1\|167240_167993_+\|subunit-of-oxidoreductase	gnl\|CDD\|239470	cd03375, TPP_OGFOR, Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR catalyzes the oxidative decarboxylation of 2-oxoglutarate to succinyl-CoA. In the reductive tricarboxylic acid cycle found in the anaerobic autotroph Hydrogenobacter thermophilus, OGFOR catalyzes the reductive carboxylation of succinyl-CoA to produce 2-oxoglutarate. Thauera aromatica OGFOR has been shown to provide reduced ferredoxin to benzoyl-CoA reductase, a key enzyme in the anaerobic metabolism of aromatic compounds. OGFOR is dependent on TPP and a divalent metal cation for activity.	1.15077e-77
CP012321.1\|AXU59319.1\|128028_128760_+\|tRNA-pseudouridine-synthase-1	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	6.63504e-129
CP012321.1\|AXU59327.1\|161719_162901_+\|membrane-associated-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	5.26538e-24
CP012321.1\|AXU59323.1\|143410_144595_-\|aspartate-aminotransferase	gnl\|CDD\|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	2.82682e-180
CP012321.1\|AXU59326.1\|160883_161723_+\|DNA-integrity-scanning-protein-DisA	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	1.4029e-80
CP012321.1\|AXU59331.1\|165917_166133_+\|ferredoxin	gnl\|CDD\|225131	COG2221, DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Energy production and conversion].	6.6539e-10

>CP012321.1|AXU59325.1|147340_147880_+|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein
MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDLCGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGFTFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLKYKKVFLVEQYMKDDLSIAE
>CP012321.1|AXU59324.1|144967_147319_+|anaerobic-ribonucleoside-triphosphate-reductase
MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLSEQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNSKTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEHSFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAAIAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNIVYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKTYQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETPIFPILIFKVKEGINLNPKDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPDTEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEELDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLTIGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATGKYKLNFSLMGTPAEGLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGHITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVCGRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR
>CP012321.1|AXU59323.1|143410_144595_-|aspartate-aminotransferase
MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVPNNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSITNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSITDKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIASLSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIAYGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFEYKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKIMA
>CP012321.1|AXU59322.1|130190_130943_+|germination-specific-N-acetylmuramoyl-L-alanine-amidase
MEYYGVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNISEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGLVILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYGAQTFYPKDKQDSKALSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGFLSNEKECKLLTDETYQEKIAWAIYIGIQKYLS
>CP012321.1|AXU59321.1|129339_129732_+|30S-ribosomal-protein-S9
MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETLIRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEGFLTRDARMKERKKYGLKAARRAPQFSKR
>CP012321.1|AXU59320.1|128879_129311_+|50S-ribosomal-protein-L13
MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTFTPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVISHAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK
>CP012321.1|AXU59319.1|128028_128760_+|tRNA-pseudouridine-synthase-1
MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETSLIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSRYSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSGSSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDIIQSKTRSRCGHTAPAQGLFLKKVHY
>CP012321.1|AXU59318.1|127193_127997_+|ABC-transporter-permease
MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWPYIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAITKQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMMTIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADELAMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI
>CP012321.1|AXU59317.1|126333_127200_+|cobalt-transporter-ATP-binding-subunit
MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGSGKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETIDKDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIAMNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVMNHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQEILKVVRGRGLC
>CP012321.1|AXU59316.1|125512_126346_+|ABC-transporter-ATP-binding-protein
MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNGSGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVEEDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMRPKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKGKKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQL
>CP012321.1|AXU59326.1|160883_161723_+|DNA-integrity-scanning-protein-DisA
MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTRAEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGRAKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTIIDAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGIGVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGGIFK
>CP012321.1|AXU59327.1|161719_162901_+|membrane-associated-protein
MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVSISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVYLKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSGPRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLKEKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKDDIDKISYIKTKPIDLADLANGEEKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDVDIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEVE
>CP012321.1|AXU59328.1|163204_164107_+|phosphate-butyryltransferase
MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANAILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTSIILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENACTVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNAVSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIILTSRADSEETKLNSIALGVLMAAKA
>CP012321.1|AXU59329.1|164128_165208_+|butyrate-kinase
MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYEKVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVGVLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALNQKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERSGGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLVYEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGEDEMIALAQGGLRVLTGEEEAQVYDN
>CP012321.1|AXU59330.1|165197_165875_+|ATP/GTP-binding-protein
MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLDVVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGGDNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLINNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKLYMREDWM
>CP012321.1|AXU59331.1|165917_166133_+|ferredoxin
MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPATVFEMEKCIGCASCATMCPDVVITVERD
>CP012321.1|AXU59332.1|166161_167241_+|2-ketoisovalerate-ferredoxin-reductase
MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELPKIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVLNVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYYRSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEVLEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKAGLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGMTPTPAEIVEKAKKIIAGELVAGGAR
>CP012321.1|AXU59333.1|167240_167993_+|subunit-of-oxidoreductase
MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDAVGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGTAEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRVSEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWGLAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK
>CP012321.1|AXU59334.1|167993_168551_+|subunit-of-oxidoreductase
MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEMRGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKEKVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPRKEKFVPLNREALQKGMDATCSKATN
>CP012321.1|AXU59335.1|168720_170067_+|phosphoglucomutase/phosphomannomutase-mutase
MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVVVGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHNPVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYVDYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGSTHPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLAQDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLDYNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEIKTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS

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Crispr_ID: CP012321_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012321_6

1076554-1076631

Orphan

Consensus_repeat	Method
AAAAAATAAGAAAGTTTATAAATA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP012321_6

>merge|CP012321|6|1076554-1076631|CRISPRCasFinder
AAAAAATAAGAAAGTTTATAAATACTAAGTTTTAAAAAAATTAATATAAACAACAAAAAAATAAAAAGTTTATAAATA

>CP012321|6|6|1076554-1076631|CRISPRCasFinder
AAAAAATAAGAAAGTTTATAAATA	CTAAGTTTTAAAAAAATTAATATAAACAAC
AAAAAAATAAAAAGTTTATAAATA

Protein	Signature genes	Signature genes Name	Protein_function
CP012321.1\|AXU60118.1\|1078367_1078781_+\|S-adenosylmethionine-decarboxylase-proenzyme	unknown	unknown	gnl\|CDD\|274523
CP012321.1\|AXU60117.1\|1076805_1078281_+\|arginine-decarboxylase	unknown	unknown	gnl\|CDD\|224893
CP012321.1\|AXU60122.1\|1081376_1082867_+\|iron-dependent-hydrogenase	unknown	unknown	gnl\|CDD\|274983
CP012321.1\|AXU60126.1\|1086245_1086596_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU60115.1\|1073404_1075270_+\|alpha-amylase	unknown	unknown	gnl\|CDD\|200477
CP012321.1\|AXU60116.1\|1075514_1076168_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
CP012321.1\|AXU60124.1\|1084787_1085714_+\|metallo-beta-lactamase-superfamily-exported-protein	unknown	unknown	gnl\|CDD\|225212
CP012321.1\|AXU60114.1\|1070979_1073400_+\|glycogen-phosphorylase	unknown	unknown	gnl\|CDD\|340853
CP012321.1\|AXU60123.1\|1083146_1084643_+\|iron-dependent-hydrogenase	unknown	unknown	gnl\|CDD\|274983
CP012321.1\|AXU60120.1\|1079651_1080530_+\|agmatinase	unknown	unknown	gnl\|CDD\|212539
CP012321.1\|AXU60121.1\|1080709_1080910_-\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
CP012321.1\|AXU60108.1\|1063163_1064744_+\|carbohydrate-kinase	unknown	unknown	gnl\|CDD\|223141
CP012321.1\|AXU60119.1\|1078810_1079662_+\|spermidine-synthase	unknown	unknown	gnl\|CDD\|234843
CP012321.1\|AXU60107.1\|1061477_1062365_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226605
CP012321.1\|AXU60112.1\|1068364_1069495_+\|glycogen-biosynthesis-protein	unknown	unknown	gnl\|CDD\|273966
CP012321.1\|AXU60113.1\|1069523_1070966_+\|glycogen-synthase	unknown	unknown	gnl\|CDD\|340822
CP012321.1\|AXU60109.1\|1064921_1065368_+\|membrane-protease-activity-regulatory-membrane-protein	unknown	unknown	gnl\|CDD\|224501
CP012321.1\|AXU60110.1\|1065388_1066432_+\|SPFH-domain/Band-7-family-protein	unknown	unknown	gnl\|CDD\|223407
CP012321.1\|AXU60125.1\|1085831_1086023_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU60111.1\|1067202_1068363_+\|glucose-1-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|179997

Protein	Function_ID	Function_description	E-value
CP012321.1\|AXU60118.1\|1078367_1078781_+\|S-adenosylmethionine-decarboxylase-proenzyme	gnl\|CDD\|274523	TIGR03330, SAM_DCase_Bsu, S-adenosylmethionine decarboxylase proenzyme, Bacillus form. Members of this protein family are the single chain precursor of the two chains of the mature S-adenosylmethionine decarboxylase as found in Methanocaldococcus jannaschii, Bacillus subtilis, and a wide range of other species. It differs substantially in architecture from the form as found in Escherichia coli, and lacks any extended homology to the eukaryotic form (TIGR00535). [Central intermediary metabolism, Polyamine biosynthesis].	5.95064e-61
CP012321.1\|AXU60117.1\|1076805_1078281_+\|arginine-decarboxylase	gnl\|CDD\|224893	COG1982, LdcC, Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism].	4.94751e-127
CP012321.1\|AXU60122.1\|1081376_1082867_+\|iron-dependent-hydrogenase	gnl\|CDD\|274983	TIGR04105, hypothetical_protein, [FeFe] hydrogenase, group B1/B3. See for descriptions of different groups.	0
CP012321.1\|AXU60115.1\|1073404_1075270_+\|alpha-amylase	gnl\|CDD\|200477	cd11338, AmyAc_CMD, Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins. Cyclomaltodextrinase (CDase; EC3.2.1.54), neopullulanase (NPase; EC 3.2.1.135), and maltogenic amylase (MA; EC 3.2.1.133) catalyze the hydrolysis of alpha-(1,4) glycosidic linkages on a number of substrates including cyclomaltodextrins (CDs), pullulan, and starch. These enzymes hydrolyze CDs and starch to maltose and pullulan to panose by cleavage of alpha-1,4 glycosidic bonds whereas alpha-amylases essentially lack activity on CDs and pullulan. They also catalyze transglycosylation of oligosaccharides to the C3-, C4- or C6-hydroxyl groups of various acceptor sugar molecules. Since these proteins are nearly indistinguishable from each other, they are referred to as cyclomaltodextrinases (CMDs). The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
CP012321.1\|AXU60116.1\|1075514_1076168_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	2.97579e-42
CP012321.1\|AXU60124.1\|1084787_1085714_+\|metallo-beta-lactamase-superfamily-exported-protein	gnl\|CDD\|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	1.68007e-47
CP012321.1\|AXU60114.1\|1070979_1073400_+\|glycogen-phosphorylase	gnl\|CDD\|340853	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	0
CP012321.1\|AXU60123.1\|1083146_1084643_+\|iron-dependent-hydrogenase	gnl\|CDD\|274983	TIGR04105, hypothetical_protein, [FeFe] hydrogenase, group B1/B3. See for descriptions of different groups.	0
CP012321.1\|AXU60120.1\|1079651_1080530_+\|agmatinase	gnl\|CDD\|212539	cd11593, Agmatinase-like_2, Agmatinase and related proteins. This family includes known and predicted bacterial and archaeal agmatinase (agmatine ureohydrolase; AUH; SpeB; EC=3.5.3.11), a binuclear manganese metalloenzyme that belongs to the ureohydrolase superfamily. It is a key enzyme in the synthesis of polyamine putrescine; it catalyzes hydrolysis of agmatine to yield urea and putrescine, the precursor for biosynthesis of higher polyamines, spermidine, and spermine. As compared to E. coli where two paths to putrescine exist, via decarboxylation of an amino acid, ornithine or arginine, a single path is found in Bacillus subtilis, where polyamine synthesis starts with agmatine; the speE and speB encode spermidine synthase and agmatinase, respectively. The level of agmatinase synthesis is very low, allowing strict control on the synthesis of putrescine and therefore, of all polyamines, consistent with polyamine levels in the cell. This subfamily belongs to the ureohydrolase superfamily, which includes arginase, agmatinase, proclavaminate amidinohydrolase, and formiminoglutamase.	8.34069e-130
CP012321.1\|AXU60121.1\|1080709_1080910_-\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.73549e-31
CP012321.1\|AXU60108.1\|1063163_1064744_+\|carbohydrate-kinase	gnl\|CDD\|223141	COG0063, COG0063, Predicted sugar kinase [Carbohydrate transport and metabolism].	9.33053e-83
CP012321.1\|AXU60119.1\|1078810_1079662_+\|spermidine-synthase	gnl\|CDD\|234843	PRK00811, PRK00811, polyamine aminopropyltransferase.	2.20299e-166
CP012321.1\|AXU60107.1\|1061477_1062365_-\|ABC-transporter-permease	gnl\|CDD\|226605	COG4120, COG4120, ABC-type uncharacterized transport system, permease component [General function prediction only].	7.23666e-82
CP012321.1\|AXU60112.1\|1068364_1069495_+\|glycogen-biosynthesis-protein	gnl\|CDD\|273966	TIGR02092, Glycogen_biosynthesis_protein_GlgD, glucose-1-phosphate adenylyltransferase, GlgD subunit. This family is GlgD, an apparent regulatory protein that appears in an alpha2/beta2 heterotetramer with GlgC (glucose-1-phosphate adenylyltransferase, TIGR02091) in a subset of bacteria that use GlgC for glycogen biosynthesis. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	4.11714e-123
CP012321.1\|AXU60113.1\|1069523_1070966_+\|glycogen-synthase	gnl\|CDD\|340822	cd03791, GT5_Glycogen_synthase_DULL1-like, Glycogen synthase GlgA and similar proteins. This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.	0
CP012321.1\|AXU60109.1\|1064921_1065368_+\|membrane-protease-activity-regulatory-membrane-protein	gnl\|CDD\|224501	COG1585, COG1585, Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	6.55918e-19
CP012321.1\|AXU60110.1\|1065388_1066432_+\|SPFH-domain/Band-7-family-protein	gnl\|CDD\|223407	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones].	2.04722e-61
CP012321.1\|AXU60111.1\|1067202_1068363_+\|glucose-1-phosphate-adenylyltransferase	gnl\|CDD\|179997	PRK05293, glgC, glucose-1-phosphate adenylyltransferase; Provisional.	0

>CP012321.1|AXU60116.1|1075514_1076168_+|GntR-family-transcriptional-regulator
MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTPAREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESDLVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKSYTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERVLREHWKTIPIAEMKKEKLL
>CP012321.1|AXU60115.1|1073404_1075270_+|alpha-amylase
MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISLEINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFYGKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDNPKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPIFEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFNMYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDNDSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISYGQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLNLIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYPWKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVNRSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN
>CP012321.1|AXU60114.1|1070979_1073400_+|glycogen-phosphorylase
MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDEIAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIEAEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNWLTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQNQCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAGKLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILLDEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVEELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQDEPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQRLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHELLDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENYGVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKENMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNSLTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYAKDIWFKRV
>CP012321.1|AXU60113.1|1069523_1070966_+|glycogen-synthase
MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKYSTIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSIYGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNIKTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITVSPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSIDKKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGTGEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAMRYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKWIKLVENAMKTDNSWKKSAKEYIETYRDICD
>CP012321.1|AXU60112.1|1068364_1069495_+|glycogen-biosynthesis-protein
MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFALSNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHREGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNNANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGNYCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKIFTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQNCVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI
>CP012321.1|AXU60111.1|1067202_1068363_+|glucose-1-phosphate-adenylyltransferase
MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLSNCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGTAHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEASRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDDFGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIYTNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNVVIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL
>CP012321.1|AXU60110.1|1065388_1066432_+|SPFH-domain/Band-7-family-protein
MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVAETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVFEIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRVELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKKEAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAMKEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLDIKEVLNDNESLKK
>CP012321.1|AXU60109.1|1064921_1065368_+|membrane-protease-activity-regulatory-membrane-protein
MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESIFLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVVVEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ
>CP012321.1|AXU60108.1|1063163_1064744_+|carbohydrate-kinase
MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIGMYNSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGINIININKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTGLKRDITGIFKEVIEIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRGFLNYDTSTLIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGKVSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERLNKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWKNRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTYINPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVNATDLISNISLTMKELLDI
>CP012321.1|AXU60107.1|1061477_1062365_-|ABC-transporter-permease
MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGASIVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLRIMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVFLDLFLKTGLGYTLKGVGDNSQMIKSLGINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGITLFKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGNLNISLKKTNAKLVPKINQKKEVL
>CP012321.1|AXU60117.1|1076805_1078281_+|arginine-decarboxylase
MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGVAILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQAIHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKVRTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLPPSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMASIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKLCINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIAKIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIPIIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK
>CP012321.1|AXU60118.1|1078367_1078781_+|S-adenosylmethionine-decarboxylase-proenzyme
MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIVDSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLKSERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV
>CP012321.1|AXU60119.1|1078810_1079662_+|spermidine-synthase
MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKFLTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKIDMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDPIGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEVYQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYVKEMLDEE
>CP012321.1|AXU60120.1|1079651_1080530_+|agmatinase
MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFASSSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSKVPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDIVGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDVLDASVFPGTGTPEPGGVNYKEFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIACKILRELCLIISDKIK
>CP012321.1|AXU60121.1|1080709_1080910_-|cold-shock-protein
MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEGEKVSFDITQGNRGPQAENVNRI
>CP012321.1|AXU60122.1|1081376_1082867_+|iron-dependent-hydrogenase
MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGEKPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPINEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEVVRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLVQKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAERMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFIGPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFGAAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGGCINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK
>CP012321.1|AXU60123.1|1083146_1084643_+|iron-dependent-hydrogenase
MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGEKARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRCPINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAISEVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKKLAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNELIERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVVFIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRGFGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCEEGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER
>CP012321.1|AXU60124.1|1084787_1085714_+|metallo-beta-lactamase-superfamily-exported-protein
MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKSDKNSVRQNGIQRSTKSSTKNTAFKTTILNTGKSDCILVEIGNKVIMIDTGEDKNGKQIVDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDSLKKADIEPVLLKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGDAEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGVLKILERLNIKTFLTSNGEVVINSDGKTLSVNQ
>CP012321.1|AXU60125.1|1085831_1086023_+|hypothetical-protein
MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFLILLLILCECGDVFDGGCGC
>CP012321.1|AXU60126.1|1086245_1086596_+|hypothetical-protein
MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILITLKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEVYQGIEDIRKVLNLE

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Crispr_ID: CP012321_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012321_7

1548822-1550109

Orphan

I-A

Consensus_repeat	Method
GTTTTATATTAACTAAGTGGTATGTAAAT	PILER-CR
GTTTTATATTAACTAAGTGGTATGTAAAT	CRISPRCasFinder
GTTTTATATTAACTAAGTGGTATGTAAAT	CRT

19 spacers

The CRISPR arrays of CP012321_7

>merge|CP012321|7|1548822-1550109|PILER-CR,CRISPRCasFinder,CRT
GTTTTATATTAACTAAGTGGTATGTAAATTATTTTCATTTTTGAGAGTTACAAAACATCTCAATGAGTTTTATATTAACTAAGTGGTATGTAAATTAAATTCGTCTAACTTAAATTAATAATAGGAGCTTTTTGTTTTATATTAACTAAGTGGTATGTAAATACAGTTGTATTAGCAACTTTAAAAGATATACAAGACTGTTTTATATTAACTAAGTGGTATGTAAATTTATTTTTAAGTCAACACTCTTTTGAGTTGGTGTATGTTTTATATTAACTAAGTGGTATGTAAATCTATGACGTAAATAGTCTATACCCTTATGTAATGAAGGTTTTATATTAACTAAGTGGTATGTAAATCTTTTTGCACGTAGTAAGAAATCTAATTAATTTTTAAAAGTTTTATATTAACTAAGTGGTATGTAAATCCACTTGTTCTTCAATTATTTTATCTACGCAGCCTAAGTTTTATATTAACTAAGTGGTATGTAAATTAGTTTAATCTATAAATTATTCCGTTGTGGCTGTTTTGTTTTATATTAACTAAGTGGTATGTAAATAGTTTCAACGAAGACCTTTTATCTAATAAAGAAAAACGTTTTATATTAACTAAGTGGTATGTAAATAAAAAAGTCTCAATAACACCAGTCGAAGCAGAAAAATCGTTTTATATTAACTAAGTGGTATGTAAATCATTGTCAACATCATCTAATTTTTTTGTTACTGTAAGTTTTATATTAACTAAGTGGTATGTAAATTAGATTTTTTCACAAATAAACTTAACGAGTACAATGAGTTTTATATTAACTAAGTGGTATGTAAATTAGTTTTAAACTTTTTTTCTGGACATATTACAACATCAAGTTTTATATTAACTAAGTGGTATGTAAATTATCTTTAGCATTATATTTTTTAGTATCAGATGTGTGGTTTTATATTAACTAAGTGGTATGTAAATATCTTTTAATTTTTATAACTAACTATTTACAAATTCAAGTTTTATATTAACTAAGTGGTATGTAAATTCTATCCACCCCCTTTTTTATAAATTTGCATTAAAAAAGTTTTATATTAACTAAGTGGTATGTAAATAAAAATATTATAGATACAAAAAAAGATTCAGAAAACAGTTTTATATTAACTAAGTGGTATGTAAATAAGTCACACCGCCCTCCACACGACACTATAATAATAGTTTTATATTAACCAAGTGGTATATAAATAGTATAATGTTGAAAAGTTAGAGAGTACAATCAAGAAATTTTACATTAACTAAAATGTATAGAATA

>CP012321|7|1|1548822-1549978|PILER-CR
GTTTTATATTAACTAAGTGGTATGTAAAT	TATTTTCATTTTTGAGAGTTACAAAACATCTCAATGA
GTTTTATATTAACTAAGTGGTATGTAAAT	TAAATTCGTCTAACTTAAATTAATAATAGGAGCTTTTT
GTTTTATATTAACTAAGTGGTATGTAAAT	ACAGTTGTATTAGCAACTTTAAAAGATATACAAGACT
GTTTTATATTAACTAAGTGGTATGTAAAT	TTATTTTTAAGTCAACACTCTTTTGAGTTGGTGTAT
GTTTTATATTAACTAAGTGGTATGTAAAT	CTATGACGTAAATAGTCTATACCCTTATGTAATGAAG
GTTTTATATTAACTAAGTGGTATGTAAAT	CTTTTTGCACGTAGTAAGAAATCTAATTAATTTTTAAAA
GTTTTATATTAACTAAGTGGTATGTAAAT	CCACTTGTTCTTCAATTATTTTATCTACGCAGCCTAA
GTTTTATATTAACTAAGTGGTATGTAAAT	TAGTTTAATCTATAAATTATTCCGTTGTGGCTGTTTT
GTTTTATATTAACTAAGTGGTATGTAAAT	AGTTTCAACGAAGACCTTTTATCTAATAAAGAAAAAC
GTTTTATATTAACTAAGTGGTATGTAAAT	AAAAAAGTCTCAATAACACCAGTCGAAGCAGAAAAATC
GTTTTATATTAACTAAGTGGTATGTAAAT	CATTGTCAACATCATCTAATTTTTTTGTTACTGTAA
GTTTTATATTAACTAAGTGGTATGTAAAT	TAGATTTTTTCACAAATAAACTTAACGAGTACAATGA
GTTTTATATTAACTAAGTGGTATGTAAAT	TAGTTTTAAACTTTTTTTCTGGACATATTACAACATCAA
GTTTTATATTAACTAAGTGGTATGTAAAT	TATCTTTAGCATTATATTTTTTAGTATCAGATGTGTG
GTTTTATATTAACTAAGTGGTATGTAAAT	ATCTTTTAATTTTTATAACTAACTATTTACAAATTCAA
GTTTTATATTAACTAAGTGGTATGTAAAT	TCTATCCACCCCCTTTTTTATAAATTTGCATTAAAAAA
GTTTTATATTAACTAAGTGGTATGTAAAT	AAAAATATTATAGATACAAAAAAAGATTCAGAAAACA
GTTTTATATTAACTAAGTGGTATGTAAAT

>CP012321|7|7|1548822-1550109|CRISPRCasFinder
GTTTTATATTAACTAAGTGGTATGTAAAT	TATTTTCATTTTTGAGAGTTACAAAACATCTCAATGA
GTTTTATATTAACTAAGTGGTATGTAAAT	TAAATTCGTCTAACTTAAATTAATAATAGGAGCTTTTT
GTTTTATATTAACTAAGTGGTATGTAAAT	ACAGTTGTATTAGCAACTTTAAAAGATATACAAGACT
GTTTTATATTAACTAAGTGGTATGTAAAT	TTATTTTTAAGTCAACACTCTTTTGAGTTGGTGTAT
GTTTTATATTAACTAAGTGGTATGTAAAT	CTATGACGTAAATAGTCTATACCCTTATGTAATGAAG
GTTTTATATTAACTAAGTGGTATGTAAAT	CTTTTTGCACGTAGTAAGAAATCTAATTAATTTTTAAAA
GTTTTATATTAACTAAGTGGTATGTAAAT	CCACTTGTTCTTCAATTATTTTATCTACGCAGCCTAA
GTTTTATATTAACTAAGTGGTATGTAAAT	TAGTTTAATCTATAAATTATTCCGTTGTGGCTGTTTT
GTTTTATATTAACTAAGTGGTATGTAAAT	AGTTTCAACGAAGACCTTTTATCTAATAAAGAAAAAC
GTTTTATATTAACTAAGTGGTATGTAAAT	AAAAAAGTCTCAATAACACCAGTCGAAGCAGAAAAATC
GTTTTATATTAACTAAGTGGTATGTAAAT	CATTGTCAACATCATCTAATTTTTTTGTTACTGTAA
GTTTTATATTAACTAAGTGGTATGTAAAT	TAGATTTTTTCACAAATAAACTTAACGAGTACAATGA
GTTTTATATTAACTAAGTGGTATGTAAAT	TAGTTTTAAACTTTTTTTCTGGACATATTACAACATCAA
GTTTTATATTAACTAAGTGGTATGTAAAT	TATCTTTAGCATTATATTTTTTAGTATCAGATGTGTG
GTTTTATATTAACTAAGTGGTATGTAAAT	ATCTTTTAATTTTTATAACTAACTATTTACAAATTCAA
GTTTTATATTAACTAAGTGGTATGTAAAT	TCTATCCACCCCCTTTTTTATAAATTTGCATTAAAAAA
GTTTTATATTAACTAAGTGGTATGTAAAT	AAAAATATTATAGATACAAAAAAAGATTCAGAAAACA
GTTTTATATTAACTAAGTGGTATGTAAAT	AAGTCACACCGCCCTCCACACGACACTATAATAATA
GTTTTATATTAACCAAGTGGTATATAAAT	AGTATAATGTTGAAAAGTTAGAGAGTACAATCAAGAA
ATTTTACATTAACTAAAATGTATAGAATA

>CP012321|7|1|1548822-1550043|CRT
GTTTTATATTAACTAAGTGGTATGTAAAT	TATTTTCATTTTTGAGAGTTACAAAACATCTCAATGA
GTTTTATATTAACTAAGTGGTATGTAAAT	TAAATTCGTCTAACTTAAATTAATAATAGGAGCTTTTT
GTTTTATATTAACTAAGTGGTATGTAAAT	ACAGTTGTATTAGCAACTTTAAAAGATATACAAGACT
GTTTTATATTAACTAAGTGGTATGTAAAT	TTATTTTTAAGTCAACACTCTTTTGAGTTGGTGTAT
GTTTTATATTAACTAAGTGGTATGTAAAT	CTATGACGTAAATAGTCTATACCCTTATGTAATGAAG
GTTTTATATTAACTAAGTGGTATGTAAAT	CTTTTTGCACGTAGTAAGAAATCTAATTAATTTTTAAAA
GTTTTATATTAACTAAGTGGTATGTAAAT	CCACTTGTTCTTCAATTATTTTATCTACGCAGCCTAA
GTTTTATATTAACTAAGTGGTATGTAAAT	TAGTTTAATCTATAAATTATTCCGTTGTGGCTGTTTT
GTTTTATATTAACTAAGTGGTATGTAAAT	AGTTTCAACGAAGACCTTTTATCTAATAAAGAAAAAC
GTTTTATATTAACTAAGTGGTATGTAAAT	AAAAAAGTCTCAATAACACCAGTCGAAGCAGAAAAATC
GTTTTATATTAACTAAGTGGTATGTAAAT	CATTGTCAACATCATCTAATTTTTTTGTTACTGTAA
GTTTTATATTAACTAAGTGGTATGTAAAT	TAGATTTTTTCACAAATAAACTTAACGAGTACAATGA
GTTTTATATTAACTAAGTGGTATGTAAAT	TAGTTTTAAACTTTTTTTCTGGACATATTACAACATCAA
GTTTTATATTAACTAAGTGGTATGTAAAT	TATCTTTAGCATTATATTTTTTAGTATCAGATGTGTG
GTTTTATATTAACTAAGTGGTATGTAAAT	ATCTTTTAATTTTTATAACTAACTATTTACAAATTCAA
GTTTTATATTAACTAAGTGGTATGTAAAT	TCTATCCACCCCCTTTTTTATAAATTTGCATTAAAAAA
GTTTTATATTAACTAAGTGGTATGTAAAT	AAAAATATTATAGATACAAAAAAAGATTCAGAAAACA
GTTTTATATTAACTAAGTGGTATGTAAAT	AAGTCACACCGCCCTCCACACGACACTATAATAATA
GTTTTATATTAACCAAGTGGTATATAAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP012321.1\|AXU60542.1\|1544629_1545058_+\|EamA-like-transporter-family-protein	unknown	unknown	gnl\|CDD\|377396
CP012321.1\|AXU60546.1\|1550434_1552168_-\|signaling-protein	unknown	unknown	gnl\|CDD\|143635
CP012321.1\|AXU60544.1\|1545910_1547266_-\|drug/sodium-antiporter	unknown	unknown	gnl\|CDD\|240548
CP012321.1\|AXU60552.1\|1558362_1559037_-\|MgtC/SapB-transporter	unknown	unknown	gnl\|CDD\|224204
CP012321.1\|AXU60539.1\|1541660_1542605_+\|membrane-protein	unknown	unknown	gnl\|CDD\|273359
CP012321.1\|AXU60545.1\|1548389_1548542_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU60541.1\|1543929_1544478_-\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU60537.1\|1539128_1539713_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376406
CP012321.1\|AXU60536.1\|1538245_1539025_+\|hydrolase	unknown	unknown	gnl\|CDD\|369792
CP012321.1\|AXU60540.1\|1542875_1543862_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|224163
CP012321.1\|AXU60551.1\|1557681_1557858_-\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU60548.1\|1553283_1555518_-\|signaling-protein	unknown	unknown	gnl\|CDD\|238923
CP012321.1\|AXU60547.1\|1552407_1553253_-\|signaling-protein	unknown	unknown	gnl\|CDD\|143635
CP012321.1\|AXU60555.1\|1560484_1560619_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU60550.1\|1557255_1557495_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU60553.1\|1559256_1559811_-\|isochorismatase	unknown	unknown	gnl\|CDD\|238496
CP012321.1\|AXU60549.1\|1556301_1557111_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133378
CP012321.1\|AXU60543.1\|1545142_1545793_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|238952
CP012321.1\|AXU60554.1\|1559888_1560254_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
CP012321.1\|AXU60538.1\|1539912_1541343_-\|sigma-54-dependent-regulatory-protein	unknown	unknown	gnl\|CDD\|226350

Protein	Function_ID	Function_description	E-value
CP012321.1\|AXU60542.1\|1544629_1545058_+\|EamA-like-transporter-family-protein	gnl\|CDD\|377396	pfam04657, DMT_YdcZ, Putative inner membrane exporter, YdcZ. DMT_YdcZ is a family of putative inner membrane exporters from both Gram-positive and Gram-negative bacteria.	2.2504e-17
CP012321.1\|AXU60546.1\|1550434_1552168_-\|signaling-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.34022e-46
CP012321.1\|AXU60544.1\|1545910_1547266_-\|drug/sodium-antiporter	gnl\|CDD\|240548	cd13143, MATE_MepA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.	6.88958e-115
CP012321.1\|AXU60552.1\|1558362_1559037_-\|MgtC/SapB-transporter	gnl\|CDD\|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	1.38574e-53
CP012321.1\|AXU60539.1\|1541660_1542605_+\|membrane-protein	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.1092e-26
CP012321.1\|AXU60548.1\|1553283_1555518_-\|signaling-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	5.33398e-92
CP012321.1\|AXU60549.1\|1556301_1557111_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	4.54289e-25
CP012321.1\|AXU60536.1\|1538245_1539025_+\|hydrolase	gnl\|CDD\|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	1.15163e-50
CP012321.1\|AXU60540.1\|1542875_1543862_-\|radical-SAM-protein	gnl\|CDD\|224163	COG1242, COG1242, Predicted Fe-S oxidoreductase [General function prediction only].	9.4852e-180
CP012321.1\|AXU60537.1\|1539128_1539713_-\|hypothetical-protein	gnl\|CDD\|376406	pfam00882, Zn_dep_PLPC, Zinc dependent phospholipase C.	9.21275e-20
CP012321.1\|AXU60547.1\|1552407_1553253_-\|signaling-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.16166e-29
CP012321.1\|AXU60553.1\|1559256_1559811_-\|isochorismatase	gnl\|CDD\|238496	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia.	3.59583e-56
CP012321.1\|AXU60543.1\|1545142_1545793_+\|ATP-binding-protein	gnl\|CDD\|238952	cd01994, Alpha_ANH_like_IV, This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily of proteins is predicted to bind ATP. This domainhas a strongly conserved motif SGGKD at the N terminus.	1.81528e-55
CP012321.1\|AXU60554.1\|1559888_1560254_-\|transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	4.48025e-25
CP012321.1\|AXU60538.1\|1539912_1541343_-\|sigma-54-dependent-regulatory-protein	gnl\|CDD\|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	8.17105e-137

>CP012321.1|AXU60545.1|1548389_1548542_+|hypothetical-protein
MDNFLQGVLASLVASLIVYLNSKLFKKVKSHSGRSDFSFELKIKFKKNKH
>CP012321.1|AXU60544.1|1545910_1547266_-|drug/sodium-antiporter
MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSKGVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSIIILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKTDGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRKNSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSVINYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICMAFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVISLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKVA
>CP012321.1|AXU60543.1|1545142_1545793_+|ATP-binding-protein
MADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTISEEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAYGDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGEEFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKNPVEYEVKGTLIKDGYGYLEIK
>CP012321.1|AXU60542.1|1544629_1545058_+|EamA-like-transporter-family-protein
MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVGAIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTLVSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN
>CP012321.1|AXU60541.1|1543929_1544478_-|hypothetical-protein
MYTNFNIDFNNFNKKENAIKFMLMGVLLIILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVLIIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGICLILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY
>CP012321.1|AXU60540.1|1542875_1543862_-|radical-SAM-protein
MFFVQAQRTILLEIGDFLDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDGSLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYAPLEVLKEKYETILELEDVIGLSISTRPDCLPDDIVEYLSELNKRTNLWVELGLQTIHDSTSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVDGIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKRDELVGPIWSLKKWEILNKIDDTLKARNSYQGCKFV
>CP012321.1|AXU60539.1|1541660_1542605_+|membrane-protein
MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLFFGFIVLGVYSSIRTPQILKINKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVLLYTSPLFLAIFSKLCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGVLSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSCMLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLFGVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI
>CP012321.1|AXU60538.1|1539912_1541343_-|sigma-54-dependent-regulatory-protein
MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKEDILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGHLEFTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPIINTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESELFGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGSLKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKYYFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPNILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFGSSYKVAKHLEISQSKANRLIRKYTNT
>CP012321.1|AXU60537.1|1539128_1539713_-|hypothetical-protein
MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYKLKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSERWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMNDLKFSAYTCNSVINYILDSILSNTIKSYHIANCG
>CP012321.1|AXU60536.1|1538245_1539025_+|hydrolase
MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRIFKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQLYFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIELYLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDICMLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS
>CP012321.1|AXU60546.1|1550434_1552168_-|signaling-protein
MSILLKKAPKLAKHIITSFYINRDINEVLKYLCENVTWIGPGEQEFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENAQMILEVNQRCTFEIIEDRGKLLIKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTEVIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPDLPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDITQLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKNYSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSDHNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNNDALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSLTKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSKADGKNCYSTYE
>CP012321.1|AXU60547.1|1552407_1553253_-|signaling-protein
MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLGMTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYKVDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVLIDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKNYVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKFDKNDY
>CP012321.1|AXU60548.1|1553283_1555518_-|signaling-protein
MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNREFMYQHIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKGIVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIRLPNEKEIYSNVTFSIGSTIWNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHVLQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDLHLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIEITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLSHNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPMECKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDFYNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQKYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQFYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFVYKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKNLTKI
>CP012321.1|AXU60549.1|1556301_1557111_+|MerR-family-transcriptional-regulator
MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNISDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKENIIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRFNILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNSNNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK
>CP012321.1|AXU60550.1|1557255_1557495_+|hypothetical-protein
MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTFPVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK
>CP012321.1|AXU60551.1|1557681_1557858_-|hypothetical-protein
MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVESCLHQVMVLVSKYN
>CP012321.1|AXU60552.1|1558362_1559037_-|MgtC/SapB-transporter
MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIVALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLTTAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISNSTDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPLIETLEI
>CP012321.1|AXU60553.1|1559256_1559811_-|isochorismatase
MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNLPVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEKKNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQVFMASLQNSFADVKNTDKFLSNYHK
>CP012321.1|AXU60554.1|1559888_1560254_-|transcriptional-regulator
MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNIYGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEYMLEHGQQEILDNKGICYNK
>CP012321.1|AXU60555.1|1560484_1560619_+|hypothetical-protein
MNISRKAMKIIELAQKIANKRGISVEEAWSEAVTEYKNKYEHIA

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Crispr_ID: CP012321_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012321_8

1660336-1661025

TypeV

I-A

Consensus_repeat	Method
GTTTTATATTAACTATATGGAATGTAAAT	PILER-CR
GTTTTATATTAACTATATGGAATGTAAAT	CRISPRCasFinder
GTTTTATATTAACTATATGGAATGTAAAT	CRT

10 spacers

The CRISPR arrays of CP012321_8

>merge|CP012321|8|1660336-1661025|PILER-CR,CRISPRCasFinder,CRT
GTTTTATATTAACTATATGGAATGTAAATTGGAATTTAAAGGCAGAAGGAACAGCTACAGTGACGGTTTTATATTAACTATATGGAATGTAAATACATTAACATTAGCAACACAATTAATAACGATTTGTGTTTTATATTAACTATATGGAATGTAAATAGAGCAGATGTCTGGTGTTTTGGATTCCCATGTCAAGGTTTTATATTAACTATATGGAATGTAAATTGAAAATCAATAGATATTCTTATATCATTGGTATCTGTTTTATATTAACTATATGGAATGTAAATATAAGAGTGGTTTAAGAAAATAAGTTATTTTTCAAAAGTTTTATATTAACTATATGGAATGTAAATTCGAATGCTATAATTTTAATATATAAAATAAATGGAGGGTTTTATATTAACTATATGGAATGTAAATACTGTTATTTTAGCAACACTTAAAAATTTACAGGACTTGTTTTATATTAACTATATGGAATGTAAATACGCTTCCTACTTTTGAAGTTCATAAAGATGATTTAAAGTTTTATATTAACTATATGGAATATAAATAGCAATTCTGATATTTTTATTCTAATCATTTGAAATCGTTTTATATTAACTATATGGAATGTAAATCCATCTTTTGTTGCTTTACATAAATTTATATTACTTATGTTTTATATTAACTATACAGAATGTAAGT

>CP012321|8|2|1660336-1660958|PILER-CR
GTTTTATATTAACTATATGGAATGTAAAT	TGGAATTTAAAGGCAGAAGGAACAGCTACAGTGACG
GTTTTATATTAACTATATGGAATGTAAAT	ACATTAACATTAGCAACACAATTAATAACGATTTGT
GTTTTATATTAACTATATGGAATGTAAAT	AGAGCAGATGTCTGGTGTTTTGGATTCCCATGTCAAG
GTTTTATATTAACTATATGGAATGTAAAT	TGAAAATCAATAGATATTCTTATATCATTGGTATCT
GTTTTATATTAACTATATGGAATGTAAAT	ATAAGAGTGGTTTAAGAAAATAAGTTATTTTTCAAAA
GTTTTATATTAACTATATGGAATGTAAAT	TCGAATGCTATAATTTTAATATATAAAATAAATGGAGG
GTTTTATATTAACTATATGGAATGTAAAT	ACTGTTATTTTAGCAACACTTAAAAATTTACAGGACTT
GTTTTATATTAACTATATGGAATGTAAAT	ACGCTTCCTACTTTTGAAGTTCATAAAGATGATTTAAA
GTTTTATATTAACTATATGGAATATAAAT	AGCAATTCTGATATTTTTATTCTAATCATTTGAAATC
GTTTTATATTAACTATATGGAATGTAAAT

>CP012321|8|8|1660336-1661025|CRISPRCasFinder
GTTTTATATTAACTATATGGAATGTAAAT	TGGAATTTAAAGGCAGAAGGAACAGCTACAGTGACG
GTTTTATATTAACTATATGGAATGTAAAT	ACATTAACATTAGCAACACAATTAATAACGATTTGT
GTTTTATATTAACTATATGGAATGTAAAT	AGAGCAGATGTCTGGTGTTTTGGATTCCCATGTCAAG
GTTTTATATTAACTATATGGAATGTAAAT	TGAAAATCAATAGATATTCTTATATCATTGGTATCT
GTTTTATATTAACTATATGGAATGTAAAT	ATAAGAGTGGTTTAAGAAAATAAGTTATTTTTCAAAA
GTTTTATATTAACTATATGGAATGTAAAT	TCGAATGCTATAATTTTAATATATAAAATAAATGGAGG
GTTTTATATTAACTATATGGAATGTAAAT	ACTGTTATTTTAGCAACACTTAAAAATTTACAGGACTT
GTTTTATATTAACTATATGGAATGTAAAT	ACGCTTCCTACTTTTGAAGTTCATAAAGATGATTTAAA
GTTTTATATTAACTATATGGAATATAAAT	AGCAATTCTGATATTTTTATTCTAATCATTTGAAATC
GTTTTATATTAACTATATGGAATGTAAAT	CCATCTTTTGTTGCTTTACATAAATTTATATTACTTAT
GTTTTATATTAACTATACAGAATGTAAGT

>CP012321|8|2|1660336-1661025|CRT
GTTTTATATTAACTATATGGAATGTAAAT	TGGAATTTAAAGGCAGAAGGAACAGCTACAGTGACG
GTTTTATATTAACTATATGGAATGTAAAT	ACATTAACATTAGCAACACAATTAATAACGATTTGT
GTTTTATATTAACTATATGGAATGTAAAT	AGAGCAGATGTCTGGTGTTTTGGATTCCCATGTCAAG
GTTTTATATTAACTATATGGAATGTAAAT	TGAAAATCAATAGATATTCTTATATCATTGGTATCT
GTTTTATATTAACTATATGGAATGTAAAT	ATAAGAGTGGTTTAAGAAAATAAGTTATTTTTCAAAA
GTTTTATATTAACTATATGGAATGTAAAT	TCGAATGCTATAATTTTAATATATAAAATAAATGGAGG
GTTTTATATTAACTATATGGAATGTAAAT	ACTGTTATTTTAGCAACACTTAAAAATTTACAGGACTT
GTTTTATATTAACTATATGGAATGTAAAT	ACGCTTCCTACTTTTGAAGTTCATAAAGATGATTTAAA
GTTTTATATTAACTATATGGAATATAAAT	AGCAATTCTGATATTTTTATTCTAATCATTTGAAATC
GTTTTATATTAACTATATGGAATGTAAAT	CCATCTTTTGTTGCTTTACATAAATTTATATTACTTAT
GTTTTATATTAACTATACAGAATGTAAGT

Protein	Signature genes	Signature genes Name	Protein_function
CP012321.1\|AXU60645.1\|1661683_1662502_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133409
CP012321.1\|AXU60643.1\|1657583_1659677_+\|signaling-protein	unknown	unknown	gnl\|CDD\|238923
CP012321.1\|AXU60650.1\|1667392_1668601_+\|tyrosyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|237360
CP012321.1\|AXU60642.1\|1656007_1656904_-\|NADP-oxidoreductase,-coenzyme-F420-dependent	unknown	unknown	gnl\|CDD\|378484
CP012321.1\|AXU60644.1\|1661192_1661465_-\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU60641.1\|1655205_1656033_-\|3-methyl-2-oxobutanoate-hydroxymethyltransferase	unknown	unknown	gnl\|CDD\|234723
CP012321.1\|AXU60652.1\|1669958_1670873_+\|transporter	unknown	unknown	gnl\|CDD\|223769
CP012321.1\|AXU60653.1\|1671095_1671641_+\|ruberythrin	unknown	unknown	gnl\|CDD\|153105
CP012321.1\|AXU60636.1\|1650234_1650804_+\|lipoprotein	unknown	unknown	unknown
CP012321.1\|AXU60651.1\|1668661_1669543_-\|polysaccharide-deacetylase	unknown	unknown	gnl\|CDD\|200569
CP012321.1\|AXU60647.1\|1664780_1665008_-\|ferrous-ion-transport-protein	unknown	unknown	gnl\|CDD\|377199
CP012321.1\|AXU60639.1\|1653745_1653928_-\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU60640.1\|1654338_1655187_-\|pantoate--beta-alanine-ligase	unknown	unknown	gnl\|CDD\|234741
CP012321.1\|AXU60638.1\|1652007_1652922_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378573
CP012321.1\|AXU60637.1\|1650970_1651618_-\|lactate-utilization-protein-B/C	unknown	unknown	gnl\|CDD\|376839
CP012321.1\|AXU60646.1\|1662634_1664755_-\|ferrous-ion-transport-protein	unknown	unknown	gnl\|CDD\|223447
CP012321.1\|AXU60635.1\|1649330_1650230_+\|iron-sulfur-cluster-binding-protein	unknown	unknown	gnl\|CDD\|274004
CP012321.1\|AXU60648.1\|1665334_1665775_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|225064
CP012321.1\|AXU60649.1\|1665947_1666916_+\|putative-membrane-protein	unknown	unknown	unknown
CP012321.1\|AXU60634.1\|1648593_1649178_+\|thioredoxin	unknown	unknown	gnl\|CDD\|239264

Protein	Function_ID	Function_description	E-value
CP012321.1\|AXU60643.1\|1657583_1659677_+\|signaling-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.29015e-88
CP012321.1\|AXU60650.1\|1667392_1668601_+\|tyrosyl-tRNA-synthetase	gnl\|CDD\|237360	PRK13354, PRK13354, tyrosyl-tRNA synthetase; Provisional.	0
CP012321.1\|AXU60642.1\|1656007_1656904_-\|NADP-oxidoreductase,-coenzyme-F420-dependent	gnl\|CDD\|378484	pfam10728, DUF2520, Domain of unknown function (DUF2520). This presumed domain is found C-terminal to a Rossmann-like domain suggesting that these proteins are oxidoreductases.	1.13018e-41
CP012321.1\|AXU60645.1\|1661683_1662502_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133409	cd04782, HTH_BltR, Helix-Turn-Helix DNA binding domain of the BltR transcription regulator. Helix-turn-helix (HTH) multidrug-efflux transporter transcription regulator, BltR (BmrR-like transporter) of Bacillus subtilis, and related proteins; N-terminal domain. Blt, like Bmr, is a membrane protein which causes the efflux of a variety of toxic substances and antibiotics. These regulators are comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the C-terminal domains are often unrelated and bind specific coactivator molecules. They share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	2.39187e-41
CP012321.1\|AXU60641.1\|1655205_1656033_-\|3-methyl-2-oxobutanoate-hydroxymethyltransferase	gnl\|CDD\|234723	PRK00311, panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase; Reviewed.	5.69992e-171
CP012321.1\|AXU60652.1\|1669958_1670873_+\|transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	5.13478e-11
CP012321.1\|AXU60653.1\|1671095_1671641_+\|ruberythrin	gnl\|CDD\|153105	cd01046, Rubrerythrin_like, rubrerythrin-like, diiron-binding domain. Rubrerythrin-like domain, similar to rubrerythrin, a nonheme iron binding domain found in many air-sensitive bacteria and archaea, and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system. The rubrerythrin protein has two domains, a binuclear metal center located within a four-helix bundle of the rubrerythrin domain, and a rubredoxin domain. The Rubrerythrin-like domains in this CD are singular domains (no C-terminus rubredoxin domain) and are phylogenetically distinct from rubrerythrin domains of rubrerythrin-rubredoxin proteins.	1.43332e-53
CP012321.1\|AXU60651.1\|1668661_1669543_-\|polysaccharide-deacetylase	gnl\|CDD\|200569	cd10944, CE4_SmPgdA_like, Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins. This family is represented by a putative polysaccharide deacetylase PgdA from the oral pathogen Streptococcus mutans (SmPgdA) and Bacillus subtilis YheN (BsYheN), which are members of the carbohydrate esterase 4 (CE4) superfamily. SmPgdA is an extracellular metal-dependent polysaccharide deacetylase with a typical CE4 fold, with metal bound to a His-His-Asp triad. It possesses de-N-acetylase activity toward a hexamer of chitooligosaccharide N-acetylglucosamine, but not shorter chitooligosaccharides or a synthetic peptidoglycan tetrasaccharide. SmPgdA plays a role in tuning cell surface properties and in interactions with (salivary) agglutinin, an essential component of the innate immune system, most likely through deacetylation of an as-yet-unidentified polysaccharide. SmPgdA shows significant homology to the catalytic domains of peptidoglycan deacetylases from Streptococcus pneumoniae (SpPgdA) and Listeria monocytogenes (LmPgdA), both of which are involved in the bacterial defense mechanism against human mucosal lysozyme. The Bacillus subtilis genome contains six polysaccharide deacetylase gene homologs: pdaA, pdaB (previously known as ybaN), yheN, yjeA, yxkH and ylxY. The biological function of BsYheN is still unknown. This family also includes many uncharacterized polysaccharide deacetylases mainly found in bacteria.	3.30794e-75
CP012321.1\|AXU60638.1\|1652007_1652922_-\|hypothetical-protein	gnl\|CDD\|378573	pfam11155, DUF2935, Domain of unknown function (DUF2935). This family of proteins with unknown function appears to be restricted to Firmicutes. The structure of this protein has been solved and each domain is composed of four alpha helices. A metal cluster composed of iron and magnesium lies between the two domains.	2.79953e-33
CP012321.1\|AXU60640.1\|1654338_1655187_-\|pantoate--beta-alanine-ligase	gnl\|CDD\|234741	PRK00380, panC, pantoate--beta-alanine ligase; Reviewed.	4.56463e-164
CP012321.1\|AXU60647.1\|1664780_1665008_-\|ferrous-ion-transport-protein	gnl\|CDD\|377199	pfam04023, FeoA, FeoA domain. This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.	1.57039e-13
CP012321.1\|AXU60637.1\|1650970_1651618_-\|lactate-utilization-protein-B/C	gnl\|CDD\|376839	pfam02589, LUD_dom, LUD domain. This entry represents a domain found in lactate utilization proteins B (LutB) and C (LutC), as well as several uncharacterized proteins. LutB and LutC are encoded by th conserved LutABC operon in bacteria. They are involved in lactate utilization and is implicated in the oxidative conversion of L-lactate into pyruvate.	3.25008e-55
CP012321.1\|AXU60635.1\|1649330_1650230_+\|iron-sulfur-cluster-binding-protein	gnl\|CDD\|274004	TIGR02163, Ferredoxin-type_protein_NapH_homolog, ferredoxin-type protein, NapH/MauN family. Most members of this family are the NapH protein, found next to NapG,in operons that encode the periplasmic nitrate reductase. Some species with this reductase lack NapC but accomplish electron transfer to NapAB in some other manner, likely to involve NapH, NapG, and/or some other protein. A few members of this protein are designated MauN and are found in methylamine utilization operons in species that appear to lack a periplasmic nitrate reductase.	3.69407e-25
CP012321.1\|AXU60646.1\|1662634_1664755_-\|ferrous-ion-transport-protein	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	4.13489e-151
CP012321.1\|AXU60648.1\|1665334_1665775_-\|acetyltransferase	gnl\|CDD\|225064	COG2153, ElaA, Predicted acyltransferase [General function prediction only].	2.07453e-35
CP012321.1\|AXU60634.1\|1648593_1649178_+\|thioredoxin	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.12409e-17

>CP012321.1|AXU60643.1|1657583_1659677_+|signaling-protein
MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPEGKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQDGTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDALIRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLVYWKKIVHPEDWNRFYKSNTEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKIDSLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLNIDDFKNVNEMYDRDFGDNIIKTLAQSIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITISAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLKASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMINIVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEEIVKIIDDENFPYQNLVLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRVFVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGKPQTATEIFDLLKLDN
>CP012321.1|AXU60642.1|1656007_1656904_-|NADP-oxidoreductase,-coenzyme-F420-dependent
MANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIYSNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAGALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRDKDTSSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTKALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNITIENAIENLISKSEKYKEIYKLLGGKNDEKYHTDF
>CP012321.1|AXU60641.1|1655205_1656033_-|3-methyl-2-oxobutanoate-hydroxymethyltransferase
MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGDSLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGRLIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSETARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQDMLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY
>CP012321.1|AXU60640.1|1654338_1655187_-|pantoate--beta-alanine-ligase
MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAVKENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGNCTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMVKDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLNPENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNFTFELNI
>CP012321.1|AXU60639.1|1653745_1653928_-|hypothetical-protein
MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVELCLHRVMILLCECGLA
>CP012321.1|AXU60638.1|1652007_1652922_-|hypothetical-protein
MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEADHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITTRELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPLLLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGELINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIKSIILPLLADHVLREANHYIRILESYKNM
>CP012321.1|AXU60637.1|1650970_1651618_-|lactate-utilization-protein-B/C
MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILDLIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFLMSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASPAVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL
>CP012321.1|AXU60636.1|1650234_1650804_+|lipoprotein
MKKFIICIIIFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDADTVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSILKKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITGGGIDYLADYNKDYYKQLDEEQKNYENKNS
>CP012321.1|AXU60635.1|1649330_1650230_+|iron-sulfur-cluster-binding-protein
MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLCVPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPFGLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKWICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGAIYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQNAITTTFSKDKKENNICAKKYRGI
>CP012321.1|AXU60634.1|1648593_1649178_+|thioredoxin
MKRFFIVVLGCIFVLGMISGCSKKESKPVEKNKNNSEWFSNLDTEDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLVVEVDKTDMITGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVDKKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE
>CP012321.1|AXU60644.1|1661192_1661465_-|hypothetical-protein
MKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKAVKLEIFYQYLIEFEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV
>CP012321.1|AXU60645.1|1661683_1662502_+|MerR-family-transcriptional-regulator
MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYYSVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKISSKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCKSKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIGKYEDSYKSYEKLKKYIYENEYKIVGNSYEESILDFFCESNEDNYMTEISIQVSR
>CP012321.1|AXU60646.1|1662634_1664755_-|ferrous-ion-transport-protein
MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNHLTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFGNPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLGIPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIPGINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDDFTKINYDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYPSTLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLFTLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLIAILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVSYTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITWIFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLATGSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTALGFLMPTILAFVVCFLTTTVYNLFI
>CP012321.1|AXU60647.1|1664780_1665008_-|ferrous-ion-transport-protein
MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRKGPKNNLTVYKIRGSKIALRQEESSLILVSDI
>CP012321.1|AXU60648.1|1665334_1665775_-|acetyltransferase
MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKNSYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIKINLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL
>CP012321.1|AXU60649.1|1665947_1666916_+|putative-membrane-protein
MNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDFIVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINKPTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLMIALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRNLNQFLCCSKKAFYICVSYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYARILFLIIILLLFFIFDVTVIGLIIINAFLNKKINIRLSQSNIVNKQINLLIEK
>CP012321.1|AXU60650.1|1667392_1668601_+|tyrosyl-tRNA-synthetase
MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGLDPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVLANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRYEGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIMMPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVNKIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQVKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGKKKFVKIELVK
>CP012321.1|AXU60651.1|1668661_1669543_-|polysaccharide-deacetylase
MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLKAERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDDGPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDYKKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLKEKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALDQIITYFKDNGYQFKILI
>CP012321.1|AXU60652.1|1669958_1670873_+|transporter
MKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTPLQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTPSKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFLTLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGYMGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLVIGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI
>CP012321.1|AXU60653.1|1671095_1671641_+|ruberythrin
MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADEHRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEAEHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEMCKDEARHGKAFLGLLNRHFGK

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Crispr_ID: CP012321_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012321_9

1722538-1722630

Orphan

Consensus_repeat	Method
GATAATTATGAAGTGTACAAACTTTACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP012321_9

>merge|CP012321|9|1722538-1722630|CRISPRCasFinder
GATAATTATGAAGTGTACAAACTTTACTCTTTAAAATAGTTGAAAGAAATGAAGCAATTAAAGTAGATAATTATGAAGTGTACAAACTTTACT

>CP012321|9|9|1722538-1722630|CRISPRCasFinder
GATAATTATGAAGTGTACAAACTTTACT	CTTTAAAATAGTTGAAAGAAATGAAGCAATTAAAGTA
GATAATTATGAAGTGTACAAACTTTACT

Protein	Signature genes	Signature genes Name	Protein_function
CP012321.1\|AXU60708.1\|1733914_1735132_+\|homoserine-dehydrogenase	unknown	unknown	gnl\|CDD\|235783
CP012321.1\|AXU60690.1\|1711295_1712165_+\|anti-sigma(v)-factor	unknown	unknown	gnl\|CDD\|378702
CP012321.1\|AXU60695.1\|1715671_1716661_+\|ketol-acid-reductoisomerase	unknown	unknown	gnl\|CDD\|235491
CP012321.1\|AXU60694.1\|1715122_1715362_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379343
CP012321.1\|AXU60710.1\|1735995_1737261_+\|histidinol-dehydrogenase	unknown	unknown	gnl\|CDD\|376389
CP012321.1\|AXU60702.1\|1725642_1726164_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|173926
CP012321.1\|AXU60691.1\|1712207_1712963_+\|anti-sigma(v)-factor	unknown	unknown	gnl\|CDD\|378702
CP012321.1\|AXU60697.1\|1718612_1719290_+\|manganese-containing-catalase	unknown	unknown	gnl\|CDD\|226076
CP012321.1\|AXU60703.1\|1726519_1727317_+\|3D/G5-domain-containing-protein	unknown	unknown	gnl\|CDD\|270620
CP012321.1\|AXU60706.1\|1729993_1730833_+\|membrane-associated-ribonuclease	unknown	unknown	gnl\|CDD\|377085
CP012321.1\|AXU60693.1\|1713830_1714592_+\|putative-metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|307807
CP012321.1\|AXU60696.1\|1716713_1718402_+\|acetolactate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|272915
CP012321.1\|AXU60704.1\|1727426_1728017_+\|arylesterase	unknown	unknown	gnl\|CDD\|239945
CP012321.1\|AXU60701.1\|1724009_1725224_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP012321.1\|AXU60698.1\|1719463_1721500_+\|thymidylate-kinase	unknown	unknown	gnl\|CDD\|224250
CP012321.1\|AXU60705.1\|1728082_1729780_+\|phosphoglucomutase	unknown	unknown	gnl\|CDD\|100092
CP012321.1\|AXU60692.1\|1713004_1713826_+\|dehydrogenase-accessory-protein	unknown	unknown	gnl\|CDD\|379212
CP012321.1\|AXU60707.1\|1731349_1733206_+\|two-component-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
CP012321.1\|AXU60709.1\|1735248_1735731_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU60699.1\|1721690_1722257_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670

Protein	Function_ID	Function_description	E-value
CP012321.1\|AXU60708.1\|1733914_1735132_+\|homoserine-dehydrogenase	gnl\|CDD\|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	5.54356e-145
CP012321.1\|AXU60690.1\|1711295_1712165_+\|anti-sigma(v)-factor	gnl\|CDD\|378702	pfam11738, DUF3298, Protein of unknown function (DUF3298). This family of bacterial protein C-terminal regions is highly conserved but the function is not known. Several members are annotated as being endo-1,4-beta-xylanase-like, but this could not be confirmed, and the structure can be defined as a heat-shock cognate 70kd protein 44kd ATPase.	3.2134e-19
CP012321.1\|AXU60695.1\|1715671_1716661_+\|ketol-acid-reductoisomerase	gnl\|CDD\|235491	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional.	0
CP012321.1\|AXU60694.1\|1715122_1715362_+\|hypothetical-protein	gnl\|CDD\|379343	pfam13710, ACT_5, ACT domain. ACT domains bind to amino acids and regulate associated enzyme domains. These ACT domains are found at the C-terminus of the RelA protein.	3.08028e-07
CP012321.1\|AXU60710.1\|1735995_1737261_+\|histidinol-dehydrogenase	gnl\|CDD\|376389	pfam00815, Histidinol_dh, Histidinol dehydrogenase.	0
CP012321.1\|AXU60702.1\|1725642_1726164_-\|acetyltransferase	gnl\|CDD\|173926	cd04301, NAT_SF, N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate. NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.	0.00940728
CP012321.1\|AXU60691.1\|1712207_1712963_+\|anti-sigma(v)-factor	gnl\|CDD\|378702	pfam11738, DUF3298, Protein of unknown function (DUF3298). This family of bacterial protein C-terminal regions is highly conserved but the function is not known. Several members are annotated as being endo-1,4-beta-xylanase-like, but this could not be confirmed, and the structure can be defined as a heat-shock cognate 70kd protein 44kd ATPase.	2.49493e-18
CP012321.1\|AXU60697.1\|1718612_1719290_+\|manganese-containing-catalase	gnl\|CDD\|226076	COG3546, COG3546, Mn-containing catalase [Inorganic ion transport and metabolism].	7.91673e-86
CP012321.1\|AXU60703.1\|1726519_1727317_+\|3D/G5-domain-containing-protein	gnl\|CDD\|270620	cd14667, 3D_containing_proteins, Non-mltA associated 3D domain containing proteins, named for 3 conserved aspartate residues. This family contains the 3D domain, named for its 3 conserved aspartates, including similar uncharacterized proteins. These proteins contain the critical active site aspartate of mltA-like lytic transglycosylases where the 3D domain forms a larger domain with the N-terminal region. This domain is also found in conjunction with numerous other domains such as the Escherichia coli MltA, a membrane-bound lytic transglycosylase comprised of 2 domains separated by a large groove, where the peptidoglycan strand binds. Domain A is made up of an N-terminal and a C-terminal portion, corresponding to the 3D domain and Domain B is inserted within the linear sequence of domain A. MltA is distinct from other bacterial LTs, which are similar to each other. Escherichia coli peptidoglycan lytic transglycosylase (LT) initiates cell wall recycling in response to damage, during bacterial fission, and cleaves peptidoglycan (PG) to create functional spaces in its wall. PG chains (also known as murein), the major components of the bacterial cell wall, are comprised of alternating beta-1-4-linked N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), and lytic transglycosylases cleave this beta-1-4 bond.	6.2905e-35
CP012321.1\|AXU60706.1\|1729993_1730833_+\|membrane-associated-ribonuclease	gnl\|CDD\|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	2.07219e-54
CP012321.1\|AXU60693.1\|1713830_1714592_+\|putative-metal-dependent-hydrolase	gnl\|CDD\|307807	pfam01863, DUF45, Protein of unknown function DUF45. This protein has no known function. Members are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C-terminus being the most conserved region, containing three conserved histidines. This motif is similar to that found in Zinc proteases, suggesting that this family may also be proteases.	4.38648e-56
CP012321.1\|AXU60696.1\|1716713_1718402_+\|acetolactate-synthase-large-subunit	gnl\|CDD\|272915	TIGR00118, Probable_acetolactate_synthase_large_subunit, acetolactate synthase, large subunit, biosynthetic type. Two groups of proteins form acetolactate from two molecules of pyruvate. The type of acetolactate synthase described in this model also catalyzes the formation of acetohydroxybutyrate from pyruvate and 2-oxobutyrate, an early step in the branched chain amino acid biosynthesis; it is therefore also termed acetohydroxyacid synthase. In bacteria, this catalytic chain is associated with a smaller regulatory chain in an alpha2/beta2 heterotetramer. Acetolactate synthase is a thiamine pyrophosphate enzyme. In this type, FAD and Mg++ are also found. Several isozymes of this enzyme are found in E. coli K12, one of which contains a frameshift in the large subunit gene and is not expressed. [Amino acid biosynthesis, Pyruvate family].	0
CP012321.1\|AXU60704.1\|1727426_1728017_+\|arylesterase	gnl\|CDD\|239945	cd04501, SGNH_hydrolase_like_4, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid.	1.53042e-86
CP012321.1\|AXU60701.1\|1724009_1725224_+\|transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	9.85248e-15
CP012321.1\|AXU60698.1\|1719463_1721500_+\|thymidylate-kinase	gnl\|CDD\|224250	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones].	0
CP012321.1\|AXU60705.1\|1728082_1729780_+\|phosphoglucomutase	gnl\|CDD\|100092	cd05799, PGM2, This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. PGM2L1 is thought to catalyze the 1,3-bisphosphoglycerate-dependent synthesis of glucose 1,6-bisphosphate and other aldose-bisphosphates that serve as cofactors for several sugar phosphomutases and possibly also as regulators of glycolytic enzymes. PGM2 and PGM2L1 belong to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
CP012321.1\|AXU60692.1\|1713004_1713826_+\|dehydrogenase-accessory-protein	gnl\|CDD\|379212	pfam13478, XdhC_C, XdhC Rossmann domain. This entry is the rossmann domain found in the Xanthine dehydrogenase accessory protein.	7.08464e-57
CP012321.1\|AXU60707.1\|1731349_1733206_+\|two-component-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.02382e-49
CP012321.1\|AXU60699.1\|1721690_1722257_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.86961e-14

>CP012321.1|AXU60699.1|1721690_1722257_-|MarR-family-transcriptional-regulator
MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYMTILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKVTDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANFMEYEEIDKIKSEALEEFAKRRNRVNKND
>CP012321.1|AXU60698.1|1719463_1721500_+|thymidylate-kinase
MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDKPIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQAMTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKSGDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMFLMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDNAMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYTFNPLEIIEVLGEEDGTFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKVFEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNESGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWDYEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQLKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNATFLAKKYNEENTIIGFLNNYILKDDKTSYYVCQSNSCSQPINDLQKLKDMILGVE
>CP012321.1|AXU60697.1|1718612_1719290_+|manganese-containing-catalase
MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLSQSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNSVNTGEIETHVLTGLSPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETIDFLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPSFEKPLKK
>CP012321.1|AXU60696.1|1716713_1718402_+|acetolactate-synthase-large-subunit
MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHIRTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVPTSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVPKDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPVIYAGGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALSNSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLSLLIERVESKNNSNWKEEIKRFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDVGQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRMNCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLANAYNIDGYKVSSIEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN
>CP012321.1|AXU60695.1|1715671_1716661_+|ketol-acid-reductoisomerase
MARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVHVVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKEGQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYTKKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVDAGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQGMQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK
>CP012321.1|AXU60694.1|1715122_1715362_+|hypothetical-protein
MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSGIKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH
>CP012321.1|AXU60693.1|1713830_1714592_+|putative-metal-dependent-hydrolase
MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITVMSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVIKELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLKLNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLVHMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII
>CP012321.1|AXU60692.1|1713004_1713826_+|dehydrogenase-accessory-protein
MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDSTIFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFIDSKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHERFPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRTKIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK
>CP012321.1|AXU60691.1|1712207_1712963_+|anti-sigma(v)-factor
MTTYKKLKKSIFKIAIFSICLLVSLVDTNPIFAGSSSNETSNSDTIKVLNAKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEFQNKMKKENNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPIFFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKNGNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR
>CP012321.1|AXU60690.1|1711295_1712165_+|anti-sigma(v)-factor
MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVNRLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEIDIPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNNSKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQMREQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGAVEFVIPYKVIKDL
>CP012321.1|AXU60701.1|1724009_1725224_+|transcriptional-regulator
MQIKIGKVIQRLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYPDIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEFRQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDIVRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRLEEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIKNKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEILEKYPIHENLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEKILDMEKMLKNKE
>CP012321.1|AXU60702.1|1725642_1726164_-|acetyltransferase
MKFERLRTSENKLYYKAMELYKISFPFHEQRKSSLQEEILKNKEYQFNLIYDKNQFVGIILCWETDDFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIILEIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYDKFNQYLRNNVMSF
>CP012321.1|AXU60703.1|1726519_1727317_+|3D/G5-domain-containing-protein
MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQKVSSFKKTVEELLDEQGIKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFDTKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIKYGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTKVYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH
>CP012321.1|AXU60704.1|1727426_1728017_+|arylesterase
MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTTSGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIGIPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMELEGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL
>CP012321.1|AXU60705.1|1728082_1729780_+|phosphoglucomutase
MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEFGTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQFCIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYWEDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQIIRKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYPNPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTHYIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQNKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKKYGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKSDVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK
>CP012321.1|AXU60706.1|1729993_1730833_+|membrane-associated-ribonuclease
MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTISSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFSRAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIFNLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWFLVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHEMLK
>CP012321.1|AXU60707.1|1731349_1733206_+|two-component-histidine-kinase
MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKVLQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSYIILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFGKNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTIGIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKEELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFDSYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKEADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEICMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFLYVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELHEGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL
>CP012321.1|AXU60708.1|1733914_1735132_+|homoserine-dehydrogenase
MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEKHKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLAECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILSKMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYLEGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNAVIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVREKCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDKGYCEKMNKMLKIS
>CP012321.1|AXU60709.1|1735248_1735731_+|hypothetical-protein
MENKKCYSEDWYERGESTAKWFQNDREEYEREAYDEDRERRGSNCGCSDSGENRPRNCERFRREAEIREREAREAFCESSEKKKEALAYECEARKLWEEAEKYWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCNCCRK
>CP012321.1|AXU60710.1|1735995_1737261_+|histidinol-dehydrogenase
MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKFDRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYPGVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKINPKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQVGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNIESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRLTNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAIQSLAPVAEKLAKEEGLYAHAKAAEVRFKK

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Crispr_ID: CP012321_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012321_10

1834656-1835998

Orphan

I-A

Consensus_repeat	Method
GTTTTATATTAACTAAGTGGTATGTAAAT	PILER-CR
GTTTTATATTAACTAAGTGGTATGTAAAT	CRISPRCasFinder
GTTTTATATTAACTAAGTGGTATGTAAAT	CRT

20 spacers

The CRISPR arrays of CP012321_10

>merge|CP012321|10|1834656-1835998|PILER-CR,CRISPRCasFinder,CRT
GTTTTATATTAACTAAGTGGTATGTAAATTCGTTATAAGTAAGACGTGAAGCATGAATATCTGTCAGTTTTATATTAACTAAGTGGTATGTAAATCTTGAAAATCCTCAGAAGCTAAAATCCCGAAAAACTGGTTTTATATTAACTAAGTGGTATGTAAATCCACTATTACTTTCTATGTCAGCTTTGTTAACTTCGGTTTTATATTAACTAAGTGGTATGTAAATAAATTCACAGAGCTTTGGTGGGAATATACAAAACGTTTTATATTAACTAAGTGGTATGTAAATATTAAAAGAATTACTATTACAACGACTACTATATTACGTTTTATATTAACTAAGTGGTATGTAAATTTCGAAAGCGGTAAAACAGCATTATCACTTTCAAAATGTTTTATATTAACTAAGTGGTATGTAAATCTGCTAATCCTGCTATTTTAACTATAGTTTCTACCGTGTTTTATATTAACTAAGTGGTATGTAAATTCAAGACTTGTTCCAAAATTTTTCACTCCAGCGCCAGGTTTTATATTAACTAAGTGGTATGTAAATAATAAAAATTACACTAATGTAGACTTAATTCCTTCCGAGTTTTATATTAACTAAGTGGTATGTAAATTTTTTAAAGTAATGGTTACTTTTTAAAATAGAAAAGTGTTTTATATTAACTAAGTGGTATGTAAATATTTTTAAAAATGTTGGTGATACATTAAAATCTATGGGTTTTATATTAACTAAGTGGTATGTAAATTTTAGTATAGATTCTAATGTATACTATTCAACTAAAGTTTTATATTAACTAAGTGGTATGTAAATAGAGTTGAGGTTGAGTTGGAGGATATTATTTAAGGGTTTTATATTAACTAAGTGGTATGTAAATTTTGAAAGTTGTAATATAATAGATTAAAAAACTAATTGTTTTATATTAACTAAGTGGTATGTAAATCAACATGTCAGTAATATTGAAACAGGAAATTCGAGTGTTTTATATTAACTAAGTGGTATGTAAATAACACTTTAAAAACTAATGTATTCAGTATAAGAGATTGTTTTATATTAACTATGTGGTATGTAAATCTTGTTAATGCAAATAAACAACATAGCACTATTAATAGTTTTATATTAACTATGTGGTATGTAAATAGGGTTTCTGATAAAATCTTCAAACATGTAAAATATGTGTTTTATATTAACTATGAGGTATGTAAATCTTATACTTAGTTAGAACTATATATCGACACAAATATGCTTTATATTAACTATATGGTATATAAATTGCAATTTTTATTCGTTGTCCAATCGCTTTGAAATTTGTTTTATGTTAACTATGTGGTATGTAAAT

>CP012321|10|3|1834656-1835799|PILER-CR
GTTTTATATTAACTAAGTGGTATGTAAAT	TCGTTATAAGTAAGACGTGAAGCATGAATATCTGTCA
GTTTTATATTAACTAAGTGGTATGTAAAT	CTTGAAAATCCTCAGAAGCTAAAATCCCGAAAAACTG
GTTTTATATTAACTAAGTGGTATGTAAAT	CCACTATTACTTTCTATGTCAGCTTTGTTAACTTCG
GTTTTATATTAACTAAGTGGTATGTAAAT	AAATTCACAGAGCTTTGGTGGGAATATACAAAAC
GTTTTATATTAACTAAGTGGTATGTAAAT	ATTAAAAGAATTACTATTACAACGACTACTATATTAC
GTTTTATATTAACTAAGTGGTATGTAAAT	TTCGAAAGCGGTAAAACAGCATTATCACTTTCAAAAT
GTTTTATATTAACTAAGTGGTATGTAAAT	CTGCTAATCCTGCTATTTTAACTATAGTTTCTACCGT
GTTTTATATTAACTAAGTGGTATGTAAAT	TCAAGACTTGTTCCAAAATTTTTCACTCCAGCGCCAG
GTTTTATATTAACTAAGTGGTATGTAAAT	AATAAAAATTACACTAATGTAGACTTAATTCCTTCCGA
GTTTTATATTAACTAAGTGGTATGTAAAT	TTTTTAAAGTAATGGTTACTTTTTAAAATAGAAAAGT
GTTTTATATTAACTAAGTGGTATGTAAAT	ATTTTTAAAAATGTTGGTGATACATTAAAATCTATGG
GTTTTATATTAACTAAGTGGTATGTAAAT	TTTAGTATAGATTCTAATGTATACTATTCAACTAAA
GTTTTATATTAACTAAGTGGTATGTAAAT	AGAGTTGAGGTTGAGTTGGAGGATATTATTTAAGG
GTTTTATATTAACTAAGTGGTATGTAAAT	TTTGAAAGTTGTAATATAATAGATTAAAAAACTAATT
GTTTTATATTAACTAAGTGGTATGTAAAT	CAACATGTCAGTAATATTGAAACAGGAAATTCGAGT
GTTTTATATTAACTAAGTGGTATGTAAAT	AACACTTTAAAAACTAATGTATTCAGTATAAGAGATT
GTTTTATATTAACTATGTGGTATGTAAAT	CTTGTTAATGCAAATAAACAACATAGCACTATTAATA
GTTTTATATTAACTATGTGGTATGTAAAT

>CP012321|10|10|1834656-1835998|CRISPRCasFinder
GTTTTATATTAACTAAGTGGTATGTAAAT	TCGTTATAAGTAAGACGTGAAGCATGAATATCTGTCA
GTTTTATATTAACTAAGTGGTATGTAAAT	CTTGAAAATCCTCAGAAGCTAAAATCCCGAAAAACTG
GTTTTATATTAACTAAGTGGTATGTAAAT	CCACTATTACTTTCTATGTCAGCTTTGTTAACTTCG
GTTTTATATTAACTAAGTGGTATGTAAAT	AAATTCACAGAGCTTTGGTGGGAATATACAAAAC
GTTTTATATTAACTAAGTGGTATGTAAAT	ATTAAAAGAATTACTATTACAACGACTACTATATTAC
GTTTTATATTAACTAAGTGGTATGTAAAT	TTCGAAAGCGGTAAAACAGCATTATCACTTTCAAAAT
GTTTTATATTAACTAAGTGGTATGTAAAT	CTGCTAATCCTGCTATTTTAACTATAGTTTCTACCGT
GTTTTATATTAACTAAGTGGTATGTAAAT	TCAAGACTTGTTCCAAAATTTTTCACTCCAGCGCCAG
GTTTTATATTAACTAAGTGGTATGTAAAT	AATAAAAATTACACTAATGTAGACTTAATTCCTTCCGA
GTTTTATATTAACTAAGTGGTATGTAAAT	TTTTTAAAGTAATGGTTACTTTTTAAAATAGAAAAGT
GTTTTATATTAACTAAGTGGTATGTAAAT	ATTTTTAAAAATGTTGGTGATACATTAAAATCTATGG
GTTTTATATTAACTAAGTGGTATGTAAAT	TTTAGTATAGATTCTAATGTATACTATTCAACTAAA
GTTTTATATTAACTAAGTGGTATGTAAAT	AGAGTTGAGGTTGAGTTGGAGGATATTATTTAAGG
GTTTTATATTAACTAAGTGGTATGTAAAT	TTTGAAAGTTGTAATATAATAGATTAAAAAACTAATT
GTTTTATATTAACTAAGTGGTATGTAAAT	CAACATGTCAGTAATATTGAAACAGGAAATTCGAGT
GTTTTATATTAACTAAGTGGTATGTAAAT	AACACTTTAAAAACTAATGTATTCAGTATAAGAGATT
GTTTTATATTAACTATGTGGTATGTAAAT	CTTGTTAATGCAAATAAACAACATAGCACTATTAATA
GTTTTATATTAACTATGTGGTATGTAAAT	AGGGTTTCTGATAAAATCTTCAAACATGTAAAATATGT
GTTTTATATTAACTATGAGGTATGTAAAT	CTTATACTTAGTTAGAACTATATATCGACACAAATAT
GCTTTATATTAACTATATGGTATATAAAT	TGCAATTTTTATTCGTTGTCCAATCGCTTTGAAATTT
GTTTTATGTTAACTATGTGGTATGTAAAT

>CP012321|10|3|1834656-1835998|CRT
GTTTTATATTAACTAAGTGGTATGTAAAT	TCGTTATAAGTAAGACGTGAAGCATGAATATCTGTCA
GTTTTATATTAACTAAGTGGTATGTAAAT	CTTGAAAATCCTCAGAAGCTAAAATCCCGAAAAACTG
GTTTTATATTAACTAAGTGGTATGTAAAT	CCACTATTACTTTCTATGTCAGCTTTGTTAACTTCG
GTTTTATATTAACTAAGTGGTATGTAAAT	AAATTCACAGAGCTTTGGTGGGAATATACAAAAC
GTTTTATATTAACTAAGTGGTATGTAAAT	ATTAAAAGAATTACTATTACAACGACTACTATATTAC
GTTTTATATTAACTAAGTGGTATGTAAAT	TTCGAAAGCGGTAAAACAGCATTATCACTTTCAAAAT
GTTTTATATTAACTAAGTGGTATGTAAAT	CTGCTAATCCTGCTATTTTAACTATAGTTTCTACCGT
GTTTTATATTAACTAAGTGGTATGTAAAT	TCAAGACTTGTTCCAAAATTTTTCACTCCAGCGCCAG
GTTTTATATTAACTAAGTGGTATGTAAAT	AATAAAAATTACACTAATGTAGACTTAATTCCTTCCGA
GTTTTATATTAACTAAGTGGTATGTAAAT	TTTTTAAAGTAATGGTTACTTTTTAAAATAGAAAAGT
GTTTTATATTAACTAAGTGGTATGTAAAT	ATTTTTAAAAATGTTGGTGATACATTAAAATCTATGG
GTTTTATATTAACTAAGTGGTATGTAAAT	TTTAGTATAGATTCTAATGTATACTATTCAACTAAA
GTTTTATATTAACTAAGTGGTATGTAAAT	AGAGTTGAGGTTGAGTTGGAGGATATTATTTAAGG
GTTTTATATTAACTAAGTGGTATGTAAAT	TTTGAAAGTTGTAATATAATAGATTAAAAAACTAATT
GTTTTATATTAACTAAGTGGTATGTAAAT	CAACATGTCAGTAATATTGAAACAGGAAATTCGAGT
GTTTTATATTAACTAAGTGGTATGTAAAT	AACACTTTAAAAACTAATGTATTCAGTATAAGAGATT
GTTTTATATTAACTATGTGGTATGTAAAT	CTTGTTAATGCAAATAAACAACATAGCACTATTAATA
GTTTTATATTAACTATGTGGTATGTAAAT	AGGGTTTCTGATAAAATCTTCAAACATGTAAAATATGT
GTTTTATATTAACTATGAGGTATGTAAAT	CTTATACTTAGTTAGAACTATATATCGACACAAATAT
GCTTTATATTAACTATATGGTATATAAAT	TGCAATTTTTATTCGTTGTCCAATCGCTTTGAAATTT
GTTTTATGTTAACTATGTGGTATGTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP012321.1\|AXU60796.1\|1836718_1836817_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU60804.1\|1845763_1846537_+\|ABC-transporter-permease	unknown	unknown	unknown
CP012321.1\|AXU60792.1\|1829393_1831751_+\|cation-transporting-ATPase	unknown	unknown	gnl\|CDD\|319795
CP012321.1\|AXU60786.1\|1818886_1819684_-\|lipoprotein	unknown	unknown	gnl\|CDD\|224381
CP012321.1\|AXU60788.1\|1821463_1823194_+\|Na+/H+-antiporter	unknown	unknown	gnl\|CDD\|224671
CP012321.1\|AXU60799.1\|1839230_1841075_+\|glycerophosphoryl-diester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176521
CP012321.1\|AXU60803.1\|1844870_1845758_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213231
CP012321.1\|AXU60787.1\|1819993_1820980_-\|lipoate-protein-ligase	unknown	unknown	gnl\|CDD\|161920
CP012321.1\|AXU60800.1\|1841396_1841981_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
CP012321.1\|AXU60801.1\|1843083_1843260_-\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU60797.1\|1837232_1837784_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|380339
CP012321.1\|AXU60794.1\|1832737_1834009_-\|guanine-deaminase	unknown	unknown	gnl\|CDD\|238628
CP012321.1\|AXU60789.1\|1823718_1824234_+\|CF-9-family-membrane-protein	unknown	unknown	gnl\|CDD\|379370
CP012321.1\|AXU60790.1\|1825039_1827514_+\|bifunctional-glycine-dehydrogenase/aminomethyl-transferase-protein	unknown	unknown	gnl\|CDD\|234769
CP012321.1\|AXU60791.1\|1827513_1828971_+\|glycine-dehydrogenase-subunit-2	unknown	unknown	gnl\|CDD\|235292
CP012321.1\|AXU60795.1\|1836406_1836694_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU60785.1\|1818184_1818784_-\|tellurium-resistance-protein	unknown	unknown	gnl\|CDD\|226595
CP012321.1\|AXU60798.1\|1837974_1838937_+\|cysteine-synthase-A	unknown	unknown	gnl\|CDD\|107204
CP012321.1\|AXU60793.1\|1831836_1832154_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377724
CP012321.1\|AXU60802.1\|1843834_1844857_+\|ABC-2-family-transporter-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP012321.1\|AXU60792.1\|1829393_1831751_+\|cation-transporting-ATPase	gnl\|CDD\|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0
CP012321.1\|AXU60786.1\|1818886_1819684_-\|lipoprotein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	3.07907e-94
CP012321.1\|AXU60788.1\|1821463_1823194_+\|Na+/H+-antiporter	gnl\|CDD\|224671	COG1757, NhaC, Na+/H+ antiporter [Energy production and conversion].	2.00354e-58
CP012321.1\|AXU60799.1\|1839230_1841075_+\|glycerophosphoryl-diester-phosphodiesterase	gnl\|CDD\|176521	cd08579, GDPD_memb_like, Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized bacterial glycerophosphodiester phosphodiesterases. In addition to a C-terminal GDPD domain, most members in this family have an N-terminus that functions as a membrane anchor.	7.29876e-94
CP012321.1\|AXU60787.1\|1819993_1820980_-\|lipoate-protein-ligase	gnl\|CDD\|161920	TIGR00545, Probable_lipoate-protein_ligase_A, lipoyltransferase and lipoate-protein ligase. One member of this group of proteins is bovine lipoyltransferase, which transfers the lipoyl group from lipoyl-AMP to the specific Lys of lipoate-dependent enzymes. However, it does not first activate lipoic acid with ATP to create lipoyl-AMP and pyrophosphate. Another member of this group, lipoate-protein ligase A from E. coli, catalyzes both the activation and the transfer of lipoate. Homology between the two is full-length, except for the bovine mitochondrial targeting signal, but is strongest toward the N-terminus. [Protein fate, Protein modification and repair].	1.55414e-92
CP012321.1\|AXU60800.1\|1841396_1841981_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	6.50127e-94
CP012321.1\|AXU60797.1\|1837232_1837784_-\|transcriptional-regulator	gnl\|CDD\|380339	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain. This family contains transcriptional regulators containing an N-terminal XRE (Xenobiotic Response Element) family helix-turn-helix (HTH) DNA-binding domain and a C-terminal cupin domain. Included in this family is Escherichia coli transcription factor SutR (YdcN) that plays a regulatory role in sulfur utilization; it regulates a set of genes involved in the generation of sulfate and its reduction, the synthesis of cysteine, the synthesis of enzymes containing Fe-S as cofactors, and the modification of tRNA with use of sulfur-containing substrates. This family belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	4.10679e-17
CP012321.1\|AXU60794.1\|1832737_1834009_-\|guanine-deaminase	gnl\|CDD\|238628	cd01303, GDEase, Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and therefore can play a role in the regulation of cellular GTP and the guanylate nucleotide pool.	1.18822e-168
CP012321.1\|AXU60789.1\|1823718_1824234_+\|CF-9-family-membrane-protein	gnl\|CDD\|379370	pfam13787, HXXEE, Protein of unknown function with HXXEE motif. This domain contains an HXXEE motif, another conserved histidine and a YXPG motif. Its function is unknown.	1.24055e-21
CP012321.1\|AXU60790.1\|1825039_1827514_+\|bifunctional-glycine-dehydrogenase/aminomethyl-transferase-protein	gnl\|CDD\|234769	PRK00451, PRK00451, aminomethyl-transferring glycine dehydrogenase subunit GcvPA.	0
CP012321.1\|AXU60803.1\|1844870_1845758_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213231	cd03264, ABC_drug_resistance_like, ABC-type multidrug transport system, ATPase component. The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	9.45424e-105
CP012321.1\|AXU60791.1\|1827513_1828971_+\|glycine-dehydrogenase-subunit-2	gnl\|CDD\|235292	PRK04366, PRK04366, aminomethyl-transferring glycine dehydrogenase subunit GcvPB.	0
CP012321.1\|AXU60785.1\|1818184_1818784_-\|tellurium-resistance-protein	gnl\|CDD\|226595	COG4110, COG4110, Uncharacterized protein involved in stress response [General function prediction only].	2.42153e-79
CP012321.1\|AXU60798.1\|1837974_1838937_+\|cysteine-synthase-A	gnl\|CDD\|107204	cd01561, CBS_like, CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.	3.00924e-108
CP012321.1\|AXU60793.1\|1831836_1832154_-\|hypothetical-protein	gnl\|CDD\|377724	pfam06865, DUF1255, Protein of unknown function (DUF1255). This family consists of several conserved hypothetical bacterial proteins of around 95 residues in length. The function of this family is unknown.	2.92347e-53

>CP012321.1|AXU60794.1|1832737_1834009_-|guanine-deaminase
MLKVLKGNIIFTKTSETFTVFENSYIMLEKGKVKGIFKEIPKEYKNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEYATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPDTLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPIQSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMRENNVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKLYWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSILERLERFIYVGDDRNIIHRYVCGKLIEEPNI
>CP012321.1|AXU60793.1|1831836_1832154_-|hypothetical-protein
MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEYTFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSYIAD
>CP012321.1|AXU60792.1|1829393_1831751_+|cation-transporting-ATPase
MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQIFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLSVIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGESDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLNAILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAVGTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMGNICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEFIFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEAKETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDKYSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNVSNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPFVPIQLSLIGAVTVGIPSFFLALEANKSRISENFLLNILKNALPGALCVTVNVIIVYNIVEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGGLFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN
>CP012321.1|AXU60791.1|1827513_1828971_+|glycine-dehydrogenase-subunit-2
MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIENMIDQDMARQSELNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHPYQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDHKRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNPSTLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFSTPHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLVRAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEANIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEAKEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR
>CP012321.1|AXU60790.1|1825039_1827514_+|bifunctional-glycine-dehydrogenase/aminomethyl-transferase-protein
MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRKSAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISTLKINDIIYTPMCYENGGVVDDLLIYKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQKITDIDLNSIKFYKSIPSTIVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVGGEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSKEKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSEYAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKMLKVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLGAGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANASMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSILRTYLQYKDCEIVEIDFCNEYGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLGVLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGKIAYVLTLQTREQHVRREKATSNICSNQALNALVASIYIATMGKEGFKEVGMQSMKKAHYTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELKNSTLLCVTEKRSKEEIDKLVGIMEGL
>CP012321.1|AXU60789.1|1823718_1824234_+|CF-9-family-membrane-protein
MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKVYENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSIIIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSLIGKFTKWMSNI
>CP012321.1|AXU60788.1|1821463_1823194_+|Na+/H+-antiporter
MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILTLIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSLADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFFDDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDAFESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISIDLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQLFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDGMKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFATGTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMGAGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKKVDEAEIELVE
>CP012321.1|AXU60787.1|1819993_1820980_-|lipoate-protein-ligase
MLLIYNEKTNSYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKNQNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPIIDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALKVKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHDIKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDFFGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK
>CP012321.1|AXU60786.1|1818886_1819684_-|lipoprotein
MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELLEELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMAGKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGLVSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPINDEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF
>CP012321.1|AXU60785.1|1818184_1818784_-|tellurium-resistance-protein
MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLRSSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRINGNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIALIENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK
>CP012321.1|AXU60795.1|1836406_1836694_+|hypothetical-protein
MKKFLYALYSFIVIIANFRLKEKNYNFILLAIFFILLLIQNGVLKTGYQNRATFYQDNYFNREDKNDKIKFMTIKIFIFLSLPLCFNILFNYLTS
>CP012321.1|AXU60796.1|1836718_1836817_+|hypothetical-protein
MIKVSLCVICSKYKVHIVIKQKFHINEEKNIK
>CP012321.1|AXU60797.1|1837232_1837784_-|transcriptional-regulator
MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDSNPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPTRNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAESIHTYHNQGEKTLKAVIINYYPV
>CP012321.1|AXU60798.1|1837974_1838937_+|cysteine-synthase-A
MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFSKKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSMERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEACNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETAAIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFAGFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL
>CP012321.1|AXU60799.1|1839230_1841075_+|glycerophosphoryl-diester-phosphodiesterase
MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALFFIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSVIICFNKSIKYEKIGLFELFKISFENSIKLLYPKNILLFIFVILIIPLVNTVLISGFIGKIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESVNLIKGKIIRTIIYSLILSLVVAIIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCIAFEEYFRLILSIFIFILDIGFISATYYQYKGVSISKNNIKKEKKSISKIVFNLVLILLISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASHAKADYAEIDVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVGEKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKTILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFVWTVNSDSLIEKMLDLNVDSIITDNPYLIESVIYWKKNGFISQVSDYLF
>CP012321.1|AXU60800.1|1841396_1841981_+|sugar-O-acetyltransferase
MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSSDLEKKEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALIAPNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTIGDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK
>CP012321.1|AXU60801.1|1843083_1843260_-|hypothetical-protein
MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVETCLHQVLLLVSRYN
>CP012321.1|AXU60802.1|1843834_1844857_+|ABC-2-family-transporter-protein
MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETESYYIDKEKGRIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNEYKDISFWKVFNYRVTNSLINVGMLIIISIIISNTYVDEVVTSVKDIILSSKEKKKALKSKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKYVILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLSVVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIKSDYISR
>CP012321.1|AXU60803.1|1844870_1845758_+|ABC-transporter-ATP-binding-protein
MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTLMKQITTLIKPDEGQILYNGENIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGALKGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEPTAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKDILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSVVLRIVSEDIPSGDNIQSVQAKFEDVYMFYFDLEDAREV
>CP012321.1|AXU60804.1|1845763_1846537_+|ABC-transporter-permease
MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYADIFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLILSIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFASFIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQMVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF

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Crispr_ID: CP012321_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012321_11

2528632-2529448

TypeV-U4

I-A

Consensus_repeat	Method
ATTTACATTCCATATAGTTAATCTAAAAC	CRISPRCasFinder
ATTTACATTCCATATAGTTAATCTAAAAC	CRT
GTTTTAGATTAACTATATGGAATGTAAAT	PILER-CR

12 spacers

c2c9_V-U4

The CRISPR arrays of CP012321_11

>merge|CP012321|11|2528632-2529448|CRISPRCasFinder,CRT,PILER-CR
ATTTTGAATCCACATAGTTAATCTAAAACACAATTATTAATTGTTTTATTAGTGAAATCACAGCAATTTACATTCCATATAGTTAATCTAAAACTCTATGTTTTCTTTTAAATAGTTATATCCTGATTCGAGATTTACATTCCATATAGTTAATCTAAAACAAGTATAAGCTTTAGAAGTGGAGTGCCTGTCCTAGTGATTTACATTCCATATAGTTAATCTAAAACCCTTAATTGGAGGTGTATATATGTTAGATTCTATTCTATTTACATTCCATATAGTTAATCTAAAACAAATGGAGGAATAGAAGTGAAAGAGAAAGTTAAGCGCATTTACATTCCATATAGTTAATCTAAAACTGTTCCTATTTTAGAACAAGATAAATTGTATAATTTGATTTACATTCCATATAGTTAATCTAAAACCAAATCTGGACTCGGGTCTGGGTCAATAGGAGGATTATTTACATTCCATATAGTTAATCTAAAACTAGATGGAATTTATTGTAATTTTTAAATTAAAAACAATTTACATTCCATATAGTTAATCTAAAACCAATCAAGTTATAAGACTCTTTTGCGCTAACCCCAAACATTTACATTCCATATAGTTAATCTAAAACGGAATAAGCAAAAATGGACTTAGATTTTAGAGCGATATTTACATTCCATATAGTTAATCTAAAACTATTTTTACTGTTCTAGTTACTTTAGTGCTTCCATCATTTACATTCCATATAGTTAATCTAAAACGAGATATTACTAGATTGAAAAAACTGAAAAAAGATAATTTACATTCCATATAGTTAATCTAAAAC

>CP012321|11|11|2528632-2529448|CRISPRCasFinder
ATTTTGAATCCACATAGTTAATCTAAAAC	ACAATTATTAATTGTTTTATTAGTGAAATCACAGCA
ATTTACATTCCATATAGTTAATCTAAAAC	TCTATGTTTTCTTTTAAATAGTTATATCCTGATTCGAG
ATTTACATTCCATATAGTTAATCTAAAAC	AAGTATAAGCTTTAGAAGTGGAGTGCCTGTCCTAGTG
ATTTACATTCCATATAGTTAATCTAAAAC	CCTTAATTGGAGGTGTATATATGTTAGATTCTATTCT
ATTTACATTCCATATAGTTAATCTAAAAC	AAATGGAGGAATAGAAGTGAAAGAGAAAGTTAAGCGC
ATTTACATTCCATATAGTTAATCTAAAAC	TGTTCCTATTTTAGAACAAGATAAATTGTATAATTTG
ATTTACATTCCATATAGTTAATCTAAAAC	CAAATCTGGACTCGGGTCTGGGTCAATAGGAGGATT
ATTTACATTCCATATAGTTAATCTAAAAC	TAGATGGAATTTATTGTAATTTTTAAATTAAAAACA
ATTTACATTCCATATAGTTAATCTAAAAC	CAATCAAGTTATAAGACTCTTTTGCGCTAACCCCAAAC
ATTTACATTCCATATAGTTAATCTAAAAC	GGAATAAGCAAAAATGGACTTAGATTTTAGAGCGAT
ATTTACATTCCATATAGTTAATCTAAAAC	TATTTTTACTGTTCTAGTTACTTTAGTGCTTCCATC
ATTTACATTCCATATAGTTAATCTAAAAC	GAGATATTACTAGATTGAAAAAACTGAAAAAAGATA
ATTTACATTCCATATAGTTAATCTAAAAC

>CP012321|11|4|2528632-2529448|CRT
ATTTTGAATCCACATAGTTAATCTAAAAC	ACAATTATTAATTGTTTTATTAGTGAAATCACAGCA
ATTTACATTCCATATAGTTAATCTAAAAC	TCTATGTTTTCTTTTAAATAGTTATATCCTGATTCGAG
ATTTACATTCCATATAGTTAATCTAAAAC	AAGTATAAGCTTTAGAAGTGGAGTGCCTGTCCTAGTG
ATTTACATTCCATATAGTTAATCTAAAAC	CCTTAATTGGAGGTGTATATATGTTAGATTCTATTCT
ATTTACATTCCATATAGTTAATCTAAAAC	AAATGGAGGAATAGAAGTGAAAGAGAAAGTTAAGCGC
ATTTACATTCCATATAGTTAATCTAAAAC	TGTTCCTATTTTAGAACAAGATAAATTGTATAATTTG
ATTTACATTCCATATAGTTAATCTAAAAC	CAAATCTGGACTCGGGTCTGGGTCAATAGGAGGATT
ATTTACATTCCATATAGTTAATCTAAAAC	TAGATGGAATTTATTGTAATTTTTAAATTAAAAACA
ATTTACATTCCATATAGTTAATCTAAAAC	CAATCAAGTTATAAGACTCTTTTGCGCTAACCCCAAAC
ATTTACATTCCATATAGTTAATCTAAAAC	GGAATAAGCAAAAATGGACTTAGATTTTAGAGCGAT
ATTTACATTCCATATAGTTAATCTAAAAC	TATTTTTACTGTTCTAGTTACTTTAGTGCTTCCATC
ATTTACATTCCATATAGTTAATCTAAAAC	GAGATATTACTAGATTGAAAAAACTGAAAAAAGATA
ATTTACATTCCATATAGTTAATCTAAAAC

>CP012321|11|4|2528697-2529448|PILER-CR
ATTTACATTCCATATAGTTAATCTAAAAC	TCTATGTTTTCTTTTAAATAGTTATATCCTGATTCGAG
ATTTACATTCCATATAGTTAATCTAAAAC	AAGTATAAGCTTTAGAAGTGGAGTGCCTGTCCTAGTG
ATTTACATTCCATATAGTTAATCTAAAAC	CCTTAATTGGAGGTGTATATATGTTAGATTCTATTCT
ATTTACATTCCATATAGTTAATCTAAAAC	AAATGGAGGAATAGAAGTGAAAGAGAAAGTTAAGCGC
ATTTACATTCCATATAGTTAATCTAAAAC	TGTTCCTATTTTAGAACAAGATAAATTGTATAATTTG
ATTTACATTCCATATAGTTAATCTAAAAC	CAAATCTGGACTCGGGTCTGGGTCAATAGGAGGATT
ATTTACATTCCATATAGTTAATCTAAAAC	TAGATGGAATTTATTGTAATTTTTAAATTAAAAACA
ATTTACATTCCATATAGTTAATCTAAAAC	CAATCAAGTTATAAGACTCTTTTGCGCTAACCCCAAAC
ATTTACATTCCATATAGTTAATCTAAAAC	GGAATAAGCAAAAATGGACTTAGATTTTAGAGCGAT
ATTTACATTCCATATAGTTAATCTAAAAC	TATTTTTACTGTTCTAGTTACTTTAGTGCTTCCATC
ATTTACATTCCATATAGTTAATCTAAAAC	GAGATATTACTAGATTGAAAAAACTGAAAAAAGATA
ATTTACATTCCATATAGTTAATCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP012321.1\|AXU61432.1\|2532021_2532453_-\|transposase-like-protein-B	c2c9_V-U4	-	gnl\|CDD\|284650
CP012321.1\|AXU61435.1\|2534629_2535124_+\|pilin-protein	unknown	unknown	gnl\|CDD\|130771
CP012321.1\|AXU61433.1\|2533151_2533343_-\|repressor	unknown	unknown	gnl\|CDD\|367747
CP012321.1\|AXU61424.1\|2527141_2527303_-\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU61425.1\|2527354_2527807_-\|prophage-antirepressor-related-protein	unknown	unknown	unknown
CP012321.1\|AXU61418.1\|2524074_2524449_-\|regulatory-protein	unknown	unknown	gnl\|CDD\|367747
CP012321.1\|AXU61419.1\|2524667_2524901_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|224393
CP012321.1\|AXU61437.1\|2536505_2536856_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372251
CP012321.1\|AXU61427.1\|2528288_2528441_-\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU61429.1\|2530833_2530986_-\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU61430.1\|2531259_2531592_-\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU61434.1\|2533447_2533825_-\|regulatory-protein	unknown	unknown	gnl\|CDD\|367747
CP012321.1\|AXU61422.1\|2525895_2526213_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU61426.1\|2527803_2528169_-\|phage-related-regulatory-protein	unknown	unknown	gnl\|CDD\|214989
CP012321.1\|AXU61423.1\|2526348_2526813_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU61421.1\|2525316_2525613_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU61420.1\|2524884_2525298_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU61428.1\|2529755_2530640_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225786
CP012321.1\|AXU61431.1\|2531618_2531873_-\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU61436.1\|2536155_2536344_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225511

Protein	Function_ID	Function_description	E-value
CP012321.1\|AXU61432.1\|2532021_2532453_-\|transposase-like-protein-B	gnl\|CDD\|284650	pfam07282, OrfB_Zn_ribbon, Putative transposase DNA-binding domain. This putative domain is found at the C-terminus of a large number of transposase proteins. This domain contains four conserved cysteines suggestive of a zinc binding domain. Given the need for transposases to bind DNA as well as the large number of DNA-binding zinc fingers we hypothesize this domain is DNA-binding.	1.03291e-23
CP012321.1\|AXU61435.1\|2534629_2535124_+\|pilin-protein	gnl\|CDD\|130771	TIGR01710, Type_II_secretion_system_protein_G, type II secretion system protein G. This model represents GspG, protein G of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	3.8278e-14
CP012321.1\|AXU61433.1\|2533151_2533343_-\|repressor	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	3.07874e-09
CP012321.1\|AXU61428.1\|2529755_2530640_-\|hypothetical-protein	gnl\|CDD\|225786	COG3247, HdeD, Uncharacterized conserved protein [Function unknown].	0.0061555
CP012321.1\|AXU61434.1\|2533447_2533825_-\|regulatory-protein	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	4.56308e-08
CP012321.1\|AXU61426.1\|2527803_2528169_-\|phage-related-regulatory-protein	gnl\|CDD\|214989	smart01040, Bro-N, BRO family, N-terminal domain. This family includes the N-terminus of baculovirus BRO and ALI motif proteins. The function of BRO proteins is unknown. It has been suggested that BRO-A and BRO-C are DNA binding proteins that influence host DNA replication and/or transcription. This Pfam domain does not include the characteristic invariant alanine, leucine, isoleucine motif of the ALI proteins.	1.14232e-22
CP012321.1\|AXU61418.1\|2524074_2524449_-\|regulatory-protein	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	4.66936e-20
CP012321.1\|AXU61437.1\|2536505_2536856_+\|hypothetical-protein	gnl\|CDD\|372251	pfam12676, DUF3796, Protein of unknown function (DUF3796). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 120 amino acids in length.	2.99688e-34
CP012321.1\|AXU61419.1\|2524667_2524901_+\|transcriptional-regulator	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	1.08383e-19
CP012321.1\|AXU61436.1\|2536155_2536344_-\|hypothetical-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.00993054

>CP012321.1|AXU61427.1|2528288_2528441_-|hypothetical-protein
MKNRRKDKRGFSVLLDKEKLDKFDEVLEEKNLTKKEWLEEKIDEELEQKE
>CP012321.1|AXU61426.1|2527803_2528169_-|phage-related-regulatory-protein
MKNELMMFEGKEIEVFEFEGRILFNSKDVANCLDIKNVNENIRLMNEKQVVKLRNSDISNTDIRKLNNAGENFLTESGVYKLIFKSRKEEAERFQGWISDEVLPSIRQTGAYINNNAIPKS
>CP012321.1|AXU61425.1|2527354_2527807_-|prophage-antirepressor-related-protein
MREKASEIEKLQLVYNSTSMLKELLDDAGFDNKSKLLTAKTLYKKAGIDLPIEINEEEHYFDTKQIASKLKIYSKSNKPAQMAVCEIIKKIDLEDGEVKGVWETNGSWTGTVNKYTKSVIDKVRTWIEENNRPTKIAGEKKNYHVFYKIE
>CP012321.1|AXU61424.1|2527141_2527303_-|hypothetical-protein
MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLSEKKLEKNNK
>CP012321.1|AXU61423.1|2526348_2526813_+|hypothetical-protein
MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKSIQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTLLFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKKKILRERKYKKRR
>CP012321.1|AXU61422.1|2525895_2526213_+|hypothetical-protein
MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIYGNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKYITI
>CP012321.1|AXU61421.1|2525316_2525613_+|hypothetical-protein
MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLIITNEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKSYLNRF
>CP012321.1|AXU61420.1|2524884_2525298_+|hypothetical-protein
MKVKSKRSFIVGIIVCMLCCASLVIYCILKDKRFLISSFLLIVIAIFNFCNAFSRKGIVEELHDSADERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSAWKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE
>CP012321.1|AXU61419.1|2524667_2524901_+|transcriptional-regulator
MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLMLAYRMAQVFGTTIEELCCLKENKEMEDKKHESKE
>CP012321.1|AXU61418.1|2524074_2524449_-|regulatory-protein
MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTTFTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALHGEDDEVDEDKLSELEEYFKNLK
>CP012321.1|AXU61428.1|2529755_2530640_-|hypothetical-protein
MVGAFVLPNYAITLSEMSNLWGNFIMWILVPIITIVLLIIAVSSMQYILVMIAFLLIIYSFIEKKIVMGLVSVLFFTYSIYLCATWEDKSLIADNKVETVKAQRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEVLVPQEYKGKKYELKVGKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIYNSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVDPLDRIKKLKELLDSGAIT
>CP012321.1|AXU61429.1|2530833_2530986_-|hypothetical-protein
MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINFKYHRKK
>CP012321.1|AXU61430.1|2531259_2531592_-|hypothetical-protein
MNDMARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVTIFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKILIDYII
>CP012321.1|AXU61431.1|2531618_2531873_-|hypothetical-protein
MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSIATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY
>CP012321.1|AXU61432.1|2532021_2532453_-|transposase-like-protein-B
MIRNRKLSRSISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWIYPSCNETHDRDINASINILKEGLRLNCIQKLKWKPSEYMNLEVNERALADDSILIKIEDEEEAMKEAEREKKRGRRR
>CP012321.1|AXU61433.1|2533151_2533343_-|repressor
MKISKLPEAELKVMRYIWESEKVLISREITKSMEQKYEWKDTTIFTVLKRLLKKRVFRNGENR
>CP012321.1|AXU61434.1|2533447_2533825_-|regulatory-protein
MKEEILIEKLLRAELIVMEYLWKKDTLMPKKEIVKEIKQIYGWHKSTIKILLKRLVDKRYLARYIINFQSYYKIIIDNKEYYTFKKKVLKSSKSIKIMHSLTTIHKNVSKEKLDLLDEYYRNLKE
>CP012321.1|AXU61435.1|2534629_2535124_+|pilin-protein
MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEADISAIKSASLSYYADESKYTDGGMISWVKKDGKIIINGGFKDDPLADKIENLGMPYNGSYLLMSSPGHEKYLELSILPEGEISKSGLDKLKSDYGSSIDIKNDQNKIDIVIKLLNDKSNT
>CP012321.1|AXU61436.1|2536155_2536344_-|hypothetical-protein
MTKYDFNFKLKVAKFYLNREGRDILIVKQYGVYDHSQVERWVNILGESELKIKKFSILYGSS
>CP012321.1|AXU61437.1|2536505_2536856_+|hypothetical-protein
MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFIIAKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAITLNVYAIKLYILEEK

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Crispr_ID: CP012321_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012321_12

2691558-2691715

Unclear

Consensus_repeat	Method
AGGTTTAAGATTAACTAAGTGGATTTCA	PILER-CR

2 spacers

cas3,cas5,cas7,cas6

The CRISPR arrays of CP012321_12

>merge|CP012321|12|2691558-2691715|PILER-CR
AAATCCGATTAGTTAATTTTAAACCTAATAATAAAACTTCTATTATATCTACTATATCAATATTTGAAATCCACTTAGTTAATCTTAAACATACAAAATCTCCAACTTATAATTATTTTCGCGATGTACCTGAAACCCACTTAGTTAATCTTAAACCT

>CP012321|12|5|2691558-2691715|PILER-CR
AAATCCGATTAGTTAATTTTAAACCTAA	TAATAAAACTTCTATTATATCTACTATATCAATATTTG
AAATCCACTTAGTTAATCTTAAACATAC	AAAATCTCCAACTTATAATTATTTTCGCGATGTACCTG
AAACCCACTTAGTTAATCTTAAACCT

Protein	Signature genes	Signature genes Name	Protein_function
CP012321.1\|AXU61579.1\|2687183_2687627_-\|tRNA-binding-protein	unknown	unknown	gnl\|CDD\|370480
CP012321.1\|AXU61587.1\|2695104_2696118_-\|CRISPR-associated-autoregulator,-Cst2-family	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
CP012321.1\|AXU61585.1\|2691856_2694265_-\|ATP-dependent-helicase	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224124
CP012321.1\|AXU61594.1\|2702568_2703504_-\|glucokinase	unknown	unknown	gnl\|CDD\|224851
CP012321.1\|AXU61580.1\|2687656_2687836_-\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
CP012321.1\|AXU61577.1\|2685819_2686383_-\|sigma-54-modulation-protein	unknown	unknown	gnl\|CDD\|238308
CP012321.1\|AXU61592.1\|2700204_2700972_+\|sugar-diacid-utilization-regulator	unknown	unknown	gnl\|CDD\|379258
CP012321.1\|AXU61581.1\|2687998_2688349_-\|histidine-triad-nucleotide-binding-protein	unknown	unknown	gnl\|CDD\|238607
CP012321.1\|AXU61582.1\|2688391_2689690_-\|radical-SAM-superfamily-protein	unknown	unknown	gnl\|CDD\|223694
CP012321.1\|AXU61586.1\|2694291_2695089_-\|CRISPR-associated-protein,-Cas5t-family	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|187789
CP012321.1\|AXU61589.1\|2697617_2698355_-\|CRISPR-associated-Cas-family-protein	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
CP012321.1\|AXU61575.1\|2684014_2685358_-\|stage-IV-sporulation-protein	unknown	unknown	gnl\|CDD\|377731
CP012321.1\|AXU61590.1\|2698455_2698632_-\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU61578.1\|2686575_2687073_-\|sensory-protein	unknown	unknown	gnl\|CDD\|320706
CP012321.1\|AXU61588.1\|2696137_2697613_-\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU61591.1\|2699065_2700175_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|236947
CP012321.1\|AXU61583.1\|2689691_2690450_-\|16S-ribosomal-RNA-methyltransferase-RsmE	unknown	unknown	gnl\|CDD\|236959
CP012321.1\|AXU61584.1\|2690468_2691416_-\|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|283886
CP012321.1\|AXU61593.1\|2701159_2702533_-\|transporter	unknown	unknown	gnl\|CDD\|129794
CP012321.1\|AXU61576.1\|2685370_2685607_-\|sporulation-protein-YqfC	unknown	unknown	gnl\|CDD\|377934

Protein	Function_ID	Function_description	E-value
CP012321.1\|AXU61579.1\|2687183_2687627_-\|tRNA-binding-protein	gnl\|CDD\|370480	pfam09424, YqeY, Yqey-like protein. The function of this domain found in the YqeY protein is uncertain.	3.14843e-57
CP012321.1\|AXU61587.1\|2695104_2696118_-\|CRISPR-associated-autoregulator,-Cst2-family	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	8.07726e-19
CP012321.1\|AXU61585.1\|2691856_2694265_-\|ATP-dependent-helicase	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	4.65429e-42
CP012321.1\|AXU61594.1\|2702568_2703504_-\|glucokinase	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	2.58887e-66
CP012321.1\|AXU61580.1\|2687656_2687836_-\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	1.30053e-12
CP012321.1\|AXU61577.1\|2685819_2686383_-\|sigma-54-modulation-protein	gnl\|CDD\|238308	cd00552, RaiA, RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY, is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal A site. RaiA is also thought to counteract miscoding at the A site thus reducing translation errors. The RaiA fold structurally resembles the double-stranded RNA-binding domain (dsRBD).	1.43831e-27
CP012321.1\|AXU61592.1\|2700204_2700972_+\|sugar-diacid-utilization-regulator	gnl\|CDD\|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	3.71654e-15
CP012321.1\|AXU61581.1\|2687998_2688349_-\|histidine-triad-nucleotide-binding-protein	gnl\|CDD\|238607	cd01276, PKCI_related, Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a hydrophobic residue) that is a signature for this family. No enzymatic activity has been reported however, for PKCI and its related members.	1.77543e-54
CP012321.1\|AXU61582.1\|2688391_2689690_-\|radical-SAM-superfamily-protein	gnl\|CDD\|223694	COG0621, MiaB, 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis].	3.75463e-179
CP012321.1\|AXU61586.1\|2694291_2695089_-\|CRISPR-associated-protein,-Cas5t-family	gnl\|CDD\|187789	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.58343e-10
CP012321.1\|AXU61589.1\|2697617_2698355_-\|CRISPR-associated-Cas-family-protein	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	3.1359e-16
CP012321.1\|AXU61575.1\|2684014_2685358_-\|stage-IV-sporulation-protein	gnl\|CDD\|377731	pfam06898, YqfD, Putative stage IV sporulation protein YqfD. This family consists of several putative bacterial stage IV sporulation (SpoIV) proteins. YqfD of Bacillus subtilis is known to be essential for efficient sporulation although its exact function is unknown.	2.02846e-106
CP012321.1\|AXU61578.1\|2686575_2687073_-\|sensory-protein	gnl\|CDD\|320706	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family. This family contains tryptophan-rich translocator protein (TSPO), an integral membrane protein that is highly conserved from bacteria to mammals. In eukaryotes, it is mainly found in the outer mitochondrial membranes of steroid-synthesizing cells of the nervous system where it transports cholesterol into mitochondria. It is known to be highly expressed in metastatic cancer, steriodogenic tissues, as well as inflammatory and neurological diseases such as Alzheimer's and Parkinson's. TSPO is also known as the peripheral benzodiazepine receptor (MBR) and its ligands include benzodiazepine drugs, implicated in regulating apoptosis. In human, a single polymorphism A147T is associated with psychiatric disorders; the mutation causes structural changes in a region implicated in cholesterol binding. TSPO is homologous to bacterial tryptophan-rich sensory proteins, and their tryptophan residues are believed to be functionally important. In bacteria, TSPO acts as a negative regulator of expression of specific photosynthesis genes in response to oxygen/light; it catalyzes a photooxidative degradation of Proto porphyrine (PpIX). R. sphaeroides TSPO (RsTSPO) is involved in porphyrin transport, similar to human, while Arabidopsis translocator protein (AtTSPO) is regulated at multiple levels in response to salt stress and perturbations in tetrapyrrole metabolism.	1.41313e-43
CP012321.1\|AXU61591.1\|2699065_2700175_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	0
CP012321.1\|AXU61583.1\|2689691_2690450_-\|16S-ribosomal-RNA-methyltransferase-RsmE	gnl\|CDD\|236959	PRK11713, PRK11713, 16S ribosomal RNA methyltransferase RsmE; Provisional.	7.40285e-85
CP012321.1\|AXU61584.1\|2690468_2691416_-\|50S-ribosomal-protein-L11-methyltransferase	gnl\|CDD\|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	5.76698e-110
CP012321.1\|AXU61593.1\|2701159_2702533_-\|transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.94143e-34
CP012321.1\|AXU61576.1\|2685370_2685607_-\|sporulation-protein-YqfC	gnl\|CDD\|377934	pfam07873, YabP, YabP family. This family of proteins is involved in spore coat assembly during the process of sporulation.	1.14572e-12

>CP012321.1|AXU61584.1|2690468_2691416_-|50S-ribosomal-protein-L11-methyltransferase
MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKKNELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGSVSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQDGDLIIELDPGMAFGTGTHETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKENVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISSGIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK
>CP012321.1|AXU61583.1|2689691_2690450_-|16S-ribosomal-RNA-methyltransferase-RsmE
MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICDKNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEVGVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEALEDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNCNVVSLGPRILRTETASVVASTIALYELSDLGGEK
>CP012321.1|AXU61582.1|2688391_2689690_-|radical-SAM-superfamily-protein
MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVINTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDRRKIVEEIKNINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCIIPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQINQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYTTLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSPRKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKYEGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL
>CP012321.1|AXU61581.1|2687998_2688349_-|histidine-triad-nucleotide-binding-protein
MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKKHYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHILAGKKLPNYEAGQN
>CP012321.1|AXU61580.1|2687656_2687836_-|30S-ribosomal-protein-S21
MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVKRKKKAEAARRKNAKK
>CP012321.1|AXU61579.1|2687183_2687627_-|tRNA-binding-protein
MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVELDEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEIVKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ
>CP012321.1|AXU61578.1|2686575_2687073_-|sensory-protein
MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQLTKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWSILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFIWFINK
>CP012321.1|AXU61577.1|2685819_2686383_-|sigma-54-modulation-protein
MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAKKDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKSIRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFYMFRNQDNFEINIVYKRKAGGYGLIEQD
>CP012321.1|AXU61576.1|2685370_2685607_-|sporulation-protein-YqfC
MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTKVKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD
>CP012321.1|AXU61575.1|2684014_2685358_-|stage-IV-sporulation-protein
MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKMEFHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTSQFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSINVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKGDVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKNIKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKELEYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPDEGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN
>CP012321.1|AXU61585.1|2691856_2694265_-|ATP-dependent-helicase
MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNLYSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIARHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSTSKVQKEIYDYIEKGILEKEDFNLEDIEDYIKEILDVDFKFNEDVLDYDYIDKLSESMFIDSDYNNGQIDDSVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLEKNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYRKNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCVIATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDVDFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVSFIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRFKFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNNKYEYGNFYILPSEDKIYDNKLKNTTKSILKDILKTNSIFTMGIRKTILDDYYDNSVVKKYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSYKIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVGLILK
>CP012321.1|AXU61586.1|2694291_2695089_-|CRISPR-associated-protein,-Cas5t-family
MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYLCDRRLKSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLKGNYYDYYKEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPSEKGCFVKEVALKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPHKYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL
>CP012321.1|AXU61587.1|2695104_2696118_-|CRISPR-associated-autoregulator,-Cst2-family
MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHAKTSIATITYDLRRMLHQEYGWNLSNIIFGKKGNIYPSIKKNVGCVDENGLETDVFGYLIPLKDKGSISKASPLRIIPFRSLNPYIGSTQLITNRGFLSSEFGRKYYDEKEENEVPRDENFPTTQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKAVKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGVIETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWYLKE
>CP012321.1|AXU61588.1|2696137_2697613_-|hypothetical-protein
MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFTCELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFVEELDKSSATEKQKEGIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDTVIKSNIEIDEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKRSGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKSFYKKLLHEKISSIRLYRFDIVKNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREPVNTKNLGKKMIDNGNLSNLKELLLDNISFLKQSTGTSREMDFVSSSYNIGLYIKLCWIVDGGEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQTIMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK
>CP012321.1|AXU61589.1|2697617_2698355_-|CRISPR-associated-Cas-family-protein
MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFNYGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKVKELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLNYIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKVREYYYINAYAGTFFLKGDMEDLNALYKMGIGYRRTENAGMVDILK
>CP012321.1|AXU61590.1|2698455_2698632_-|hypothetical-protein
MNLKKKEKIVKPVLKKLTEIVLNILSKKILNYAIYAISVLIVTKVVINIDLYISILYY
>CP012321.1|AXU61591.1|2699065_2700175_+|ABC-transporter-ATP-binding-protein
MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKSTTLRMIAGLEEISEGELYIGDKLVNNIEPKDRDIAMVFQNYALYPHLSVYENMAFALKLRKLPKDEIDKKVKEAAKILDLLPFLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDEPLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIATPQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKDNYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITIRFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR
>CP012321.1|AXU61592.1|2700204_2700972_+|sugar-diacid-utilization-regulator
MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDFLDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINVTTQNIIETETYQSTYIFYLGKLDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLIRYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTLVYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI
>CP012321.1|AXU61593.1|2701159_2702533_-|transporter
MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISFTTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILIFIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLGGWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMIFILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQFIILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRFPLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDSIGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILKKELRKVE
>CP012321.1|AXU61594.1|2702568_2703504_-|glucokinase
MYYIGVDIGGTGIQAGVVDNHGKIIFRAECKTVIEKGFEGILNDIKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPDVEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEIGHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNAKMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGIEDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL

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Crispr_ID: CP012321_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012321_13

2775325-2775880

Orphan

I-A

Consensus_repeat	Method
GTTTTATATTAACTATATGGAATGTAAAT	PILER-CR
ATTTACATTCCATATAGTTAATATAAAAC	CRISPRCasFinder
ATTTACATTCCATATAGTTAATATAAAAC	CRT

8 spacers

The CRISPR arrays of CP012321_13

>merge|CP012321|13|2775325-2775880|PILER-CR,CRISPRCasFinder,CRT
ATTTACATTCCATATAGTTAATATAAAACTTGTGTTTATTGTGATAGTGCCGAACAGGTGTTAATACGATTTACATTCCATATAGTTAATATAAAACTATACTTTAATACGTCAAATTAGACTTGACCTAAACAAATTTACATTCCATATAGTTAATATAAAACTTTTTCTGATGTTCCTAAGTCTGCTACTTCTATAGCATTTACATTCCATATAGTTAATATAAAACTTTTTGCTCTATATCGCGTTAGGCAAATACAAGGATAATTTACATTCCATATAGTTAATATAAAACAACAATAAAAGTCAATTAGAAATGTTTATGGAAAACAATTTACATTCCATATAGTTAATATAAAACTATTCCCGAAACTGAAAGAAATCAATGGACACCTTTATTTACATTCCATATAGTTAATATAAAACAAGTCAAAAGGTTAAATTTAAATAAAATTATACTTCTATTTACATTCCATATAGTTAATATAAAACCCAATAGTAAATATAAATCAAGTTGTTGATGCTTTATTTACATTCCATATAGTTAATATAAAAC

>CP012321|13|6|2775325-2775880|PILER-CR
ATTTACATTCCATATAGTTAATATAAAAC	TTGTGTTTATTGTGATAGTGCCGAACAGGTGTTAATACG
ATTTACATTCCATATAGTTAATATAAAAC	TATACTTTAATACGTCAAATTAGACTTGACCTAAACAA
ATTTACATTCCATATAGTTAATATAAAAC	TTTTTCTGATGTTCCTAAGTCTGCTACTTCTATAGC
ATTTACATTCCATATAGTTAATATAAAAC	TTTTTGCTCTATATCGCGTTAGGCAAATACAAGGATA
ATTTACATTCCATATAGTTAATATAAAAC	AACAATAAAAGTCAATTAGAAATGTTTATGGAAAACA
ATTTACATTCCATATAGTTAATATAAAAC	TATTCCCGAAACTGAAAGAAATCAATGGACACCTTT
ATTTACATTCCATATAGTTAATATAAAAC	AAGTCAAAAGGTTAAATTTAAATAAAATTATACTTCT
ATTTACATTCCATATAGTTAATATAAAAC	CCAATAGTAAATATAAATCAAGTTGTTGATGCTTT
ATTTACATTCCATATAGTTAATATAAAAC

>CP012321|13|12|2775325-2775880|CRISPRCasFinder
ATTTACATTCCATATAGTTAATATAAAAC	TTGTGTTTATTGTGATAGTGCCGAACAGGTGTTAATACG
ATTTACATTCCATATAGTTAATATAAAAC	TATACTTTAATACGTCAAATTAGACTTGACCTAAACAA
ATTTACATTCCATATAGTTAATATAAAAC	TTTTTCTGATGTTCCTAAGTCTGCTACTTCTATAGC
ATTTACATTCCATATAGTTAATATAAAAC	TTTTTGCTCTATATCGCGTTAGGCAAATACAAGGATA
ATTTACATTCCATATAGTTAATATAAAAC	AACAATAAAAGTCAATTAGAAATGTTTATGGAAAACA
ATTTACATTCCATATAGTTAATATAAAAC	TATTCCCGAAACTGAAAGAAATCAATGGACACCTTT
ATTTACATTCCATATAGTTAATATAAAAC	AAGTCAAAAGGTTAAATTTAAATAAAATTATACTTCT
ATTTACATTCCATATAGTTAATATAAAAC	CCAATAGTAAATATAAATCAAGTTGTTGATGCTTT
ATTTACATTCCATATAGTTAATATAAAAC

>CP012321|13|5|2775325-2775880|CRT
ATTTACATTCCATATAGTTAATATAAAAC	TTGTGTTTATTGTGATAGTGCCGAACAGGTGTTAATACG
ATTTACATTCCATATAGTTAATATAAAAC	TATACTTTAATACGTCAAATTAGACTTGACCTAAACAA
ATTTACATTCCATATAGTTAATATAAAAC	TTTTTCTGATGTTCCTAAGTCTGCTACTTCTATAGC
ATTTACATTCCATATAGTTAATATAAAAC	TTTTTGCTCTATATCGCGTTAGGCAAATACAAGGATA
ATTTACATTCCATATAGTTAATATAAAAC	AACAATAAAAGTCAATTAGAAATGTTTATGGAAAACA
ATTTACATTCCATATAGTTAATATAAAAC	TATTCCCGAAACTGAAAGAAATCAATGGACACCTTT
ATTTACATTCCATATAGTTAATATAAAAC	AAGTCAAAAGGTTAAATTTAAATAAAATTATACTTCT
ATTTACATTCCATATAGTTAATATAAAAC	CCAATAGTAAATATAAATCAAGTTGTTGATGCTTT
ATTTACATTCCATATAGTTAATATAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP012321.1\|AXU61657.1\|2781223_2783644_-\|leucyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|234743
CP012321.1\|AXU61658.1\|2783997_2784348_-\|iojap-family-protein	unknown	unknown	gnl\|CDD\|376779
CP012321.1\|AXU61647.1\|2768437_2768920_-\|PTS-system-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|376324
CP012321.1\|AXU61655.1\|2778266_2779385_+\|integrase	unknown	unknown	gnl\|CDD\|271189
CP012321.1\|AXU61652.1\|2774476_2774860_-\|regulatory-protein	unknown	unknown	gnl\|CDD\|367747
CP012321.1\|AXU61653.1\|2776165_2776324_-\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU61645.1\|2766000_2767551_-\|PTS-system-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|273925
CP012321.1\|AXU61650.1\|2771554_2773183_+\|aspartate-aminotransferase	unknown	unknown	gnl\|CDD\|163513
CP012321.1\|AXU61644.1\|2764551_2765904_-\|6-phospho-alpha-glucosidase	unknown	unknown	gnl\|CDD\|133434
CP012321.1\|AXU61649.1\|2769678_2770896_-\|threonine-dehydratase-catabolic	unknown	unknown	gnl\|CDD\|236182
CP012321.1\|AXU61651.1\|2773303_2774299_+\|L-asparaginase	unknown	unknown	gnl\|CDD\|199208
CP012321.1\|AXU61654.1\|2776682_2778053_-\|cell-surface-protein	unknown	unknown	gnl\|CDD\|380277
CP012321.1\|AXU61643.1\|2763662_2764376_-\|AraC-family-transcription-regulator	unknown	unknown	gnl\|CDD\|225080
CP012321.1\|AXU61662.1\|2786793_2788797_+\|glycogen-branching-protein	unknown	unknown	gnl\|CDD\|215246
CP012321.1\|AXU61660.1\|2785037_2785727_-\|nicotinate-nucleotide-adenylyltransferase	unknown	unknown	gnl\|CDD\|234611
CP012321.1\|AXU61646.1\|2767601_2768417_-\|transcriptional-antiterminator	unknown	unknown	gnl\|CDD\|170086
CP012321.1\|AXU61661.1\|2786002_2786641_+\|recombination-regulator-RecX	unknown	unknown	gnl\|CDD\|234646
CP012321.1\|AXU61656.1\|2779701_2780370_-\|vanZF-protein	unknown	unknown	gnl\|CDD\|377417
CP012321.1\|AXU61659.1\|2784464_2785037_-\|metal-dependent-phosphohydrolase	unknown	unknown	gnl\|CDD\|224627
CP012321.1\|AXU61648.1\|2769203_2769584_-\|translation-inhibitor-endoribonuclease	unknown	unknown	gnl\|CDD\|129116

Protein	Function_ID	Function_description	E-value
CP012321.1\|AXU61649.1\|2769678_2770896_-\|threonine-dehydratase-catabolic	gnl\|CDD\|236182	PRK08198, PRK08198, threonine dehydratase; Provisional.	0
CP012321.1\|AXU61657.1\|2781223_2783644_-\|leucyl-tRNA-synthetase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
CP012321.1\|AXU61647.1\|2768437_2768920_-\|PTS-system-transporter-subunit-IIA	gnl\|CDD\|376324	pfam00358, PTS_EIIA_1, phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1.	7.48839e-57
CP012321.1\|AXU61655.1\|2778266_2779385_+\|integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	8.44818e-44
CP012321.1\|AXU61652.1\|2774476_2774860_-\|regulatory-protein	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	6.20032e-19
CP012321.1\|AXU61645.1\|2766000_2767551_-\|PTS-system-transporter-subunit-IIBC	gnl\|CDD\|273925	TIGR02005, PTS-IIBC-alpha, PTS system, alpha-glucoside-specific IIBC component. This model represents a family of fused PTS enzyme II B and C domains. A gene from Clostridium has been partially characterized as a maltose transporter, while genes from Fusobacterium and Klebsiella have been proposed to transport the five non-standard isomers of sucrose. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.41453e-101
CP012321.1\|AXU61650.1\|2771554_2773183_+\|aspartate-aminotransferase	gnl\|CDD\|163513	TIGR03801, For_A_Pyridoxal-5-_Phosphate, aspartate 4-decarboxylase. This enzyme, aspartate 4-decarboxylase (EC 4.1.1.12), removes the side-chain carboxylate from L-aspartate, converting it to L-alanine plus carbon dioxide. It is a PLP-dependent enzyme, homologous to aspartate aminotransferase (EC 2.6.1.1). [Energy metabolism, Amino acids and amines].	0
CP012321.1\|AXU61644.1\|2764551_2765904_-\|6-phospho-alpha-glucosidase	gnl\|CDD\|133434	cd05298, GH4_GlvA_pagL_like, Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases. Bacillus subtilis GlvA and Clostridium acetobutylicum pagL are 6-phospho-alpha-glucosidase, catalyzing the hydrolysis of alpha-glucopyranoside bonds to release glucose from oligosaccharides. The substrate specificities of other members of this subgroup are unknown. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP_PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases, which include 6-phospho-beta-glucosidases, 6-phospho-alpha-glucosidases, alpha-glucosidases/alpha-glucuronidases (only from Thermotoga), and alpha-galactosidases. Members of this subfamily are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
CP012321.1\|AXU61654.1\|2776682_2778053_-\|cell-surface-protein	gnl\|CDD\|380277	NF033435, S-layer_Clost, S-layer protein SlpA. In Clostridiodes difficile, the S-layer protein precursor, SlpA, is one member of a large paralogous family of protein that share several cell wall-binding repeats. SlpA is cleaved into a larger and smaller protein. The S-layer protein itself is important to adhesion, and portions of it are highly variable, and then N-terminal and C-terminal are well-conserved.	1.87117e-19
CP012321.1\|AXU61658.1\|2783997_2784348_-\|iojap-family-protein	gnl\|CDD\|376779	pfam02410, RsfS, Ribosomal silencing factor during starvation. This family is expressed by almost all bacterial and eukaryotic genomes but not by archaea. Its function is to down-regulate protein synthesis under conditions of nutrient shortage, and it does this by binding to protein L14 of the large ribosomal subunit, thus acting as a ribosomal silencing factor (RsfS) by blocking the joining of the ribosomal subunits. This family is structurally homologous to nucleotidyltransferases.	7.43119e-49
CP012321.1\|AXU61651.1\|2773303_2774299_+\|L-asparaginase	gnl\|CDD\|199208	cd08964, L-asparaginase_II, Type II (periplasmic) bacterial L-asparaginase. Asparaginases (amidohydrolases, E.C. 3.5.1.1) are enzymes that catalyze the hydrolysis of asparagine to aspartic acid and ammonia. In bacteria, there are two classes of amidohydrolases. This model represents type II L-asparaginases, which tend to be highly specific for asparagine and localized to the periplasm. They are potent antileukemic agents and have been used in the treatment of acute lymphoblastic leukemia (ALL), but not without severe side effects. Tumor cells appear to have a heightened dependence on exogenous L-aspartate, and depleting their surroundings of L-aspartate may starve cancerous ALL cells. Type II L-asparaginase acts as a tetramer, which is actually a dimer of two tightly bound dimers. A conserved threonine residue is thought to supply the nucleophile hydroxy-group that attacks the amide bond. Many bacterial L-asparaginases have both L-asparagine and L-glutamine hydrolysis activities, to a different degree, and some of them are annotated as asparaginase/glutaminase.	8.27962e-141
CP012321.1\|AXU61661.1\|2786002_2786641_+\|recombination-regulator-RecX	gnl\|CDD\|234646	PRK00117, recX, recombination regulator RecX; Reviewed.	3.67554e-47
CP012321.1\|AXU61643.1\|2763662_2764376_-\|AraC-family-transcription-regulator	gnl\|CDD\|225080	COG2169, Ada, Adenosine deaminase [Nucleotide transport and metabolism].	5.57984e-15
CP012321.1\|AXU61662.1\|2786793_2788797_+\|glycogen-branching-protein	gnl\|CDD\|215246	PLN02447, PLN02447, 1,4-alpha-glucan-branching enzyme.	0
CP012321.1\|AXU61660.1\|2785037_2785727_-\|nicotinate-nucleotide-adenylyltransferase	gnl\|CDD\|234611	PRK00071, nadD, nicotinate-nucleotide adenylyltransferase.	9.36329e-79
CP012321.1\|AXU61646.1\|2767601_2768417_-\|transcriptional-antiterminator	gnl\|CDD\|170086	PRK09772, PRK09772, transcriptional antiterminator BglG; Provisional.	2.51602e-51
CP012321.1\|AXU61656.1\|2779701_2780370_-\|vanZF-protein	gnl\|CDD\|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	3.2707e-18
CP012321.1\|AXU61659.1\|2784464_2785037_-\|metal-dependent-phosphohydrolase	gnl\|CDD\|224627	COG1713, COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism].	4.17724e-52
CP012321.1\|AXU61648.1\|2769203_2769584_-\|translation-inhibitor-endoribonuclease	gnl\|CDD\|129116	TIGR00004, RutC_family_protein, reactive intermediate/imine deaminase. This protein was described initially as an inhibitor of protein synthesis intiation, then as an endoribonuclease active on single-stranded mRNA, endoribonuclease L-PSP. Members of this family, conserved in all domains of life and often with several members per bacterial genome, appear to catalyze a reaction that minimizes toxic by-products from reactions catalyzed by pyridoxal phosphate-dependent enzymes. [Cellular processes, Other].	6.43782e-69

>CP012321.1|AXU61652.1|2774476_2774860_-|regulatory-protein
MLNKKLPDAELKIMKYIWNTGYKTVISKDVADEIEKTYAWKHTTTITLLARLTKKGFFISQRIGKHVHYRVLIKEKEYLKIEGKRIFGGLHKNPLSELISKLHDGEEITEEKIIEIGNWIKSWKDED
>CP012321.1|AXU61651.1|2773303_2774299_+|L-asparaginase
MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNIDKVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFLDLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLASEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYVGENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVFDSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC
>CP012321.1|AXU61650.1|2771554_2773183_+|aspartate-aminotransferase
MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAGRGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDMPGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQEMKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPNLPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDETSCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWRLGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNHTAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAAYYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIRISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK
>CP012321.1|AXU61649.1|2769678_2770896_-|threonine-dehydratase-catabolic
MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCENLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPATAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTISLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKNGKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIVSEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFSTIMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIKKAIEEKGFKIIEL
>CP012321.1|AXU61648.1|2769203_2769584_-|translation-inhibitor-endoribonuclease
MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVVEGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKPARACVEVARLPKDVKVEIEVIAVL
>CP012321.1|AXU61647.1|2768437_2768920_-|PTS-system-transporter-subunit-IIA
MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAIIPNSDVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGDTVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
>CP012321.1|AXU61646.1|2767601_2768417_-|transcriptional-antiterminator
MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKIEKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFAIDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVNLQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQDDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL
>CP012321.1|AXU61645.1|2766000_2767551_-|PTS-system-transporter-subunit-IIBC
MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGVLPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIYLTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRTSNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFGLFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERFSDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDFMFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMMILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGGKENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRAVEDFLEAY
>CP012321.1|AXU61644.1|2764551_2765904_-|6-phospho-alpha-glucosidase
MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDKVAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYGCVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRPNARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIKEYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTYYLLSKETVEHSNINCTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISDLAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGLMMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
>CP012321.1|AXU61643.1|2763662_2764376_-|AraC-family-transcription-regulator
MITNNLEADTHSHCMLQLFLGIEDSIEITVNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDNNGLEKLRQQGTFLIDNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCDNHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMTAGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY
>CP012321.1|AXU61653.1|2776165_2776324_-|hypothetical-protein
MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDLKIRFHKTK
>CP012321.1|AXU61654.1|2776682_2778053_-|cell-surface-protein
MKLKKLLSLGLVSMFVAGFPISANALETIYTIQGKDKYETAALIADEQNYTTAILINADSTMADGLSASGLAGATNAPIFLTKKNNIPNATLKRVEKAKKVYIIGGESSIDKATETLLKDKGIEAKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAFKGEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMSDKLVNDTNSTRLGGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDILKNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSNHIIWQDKGSYLECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDFNSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGEDFFEYK
>CP012321.1|AXU61655.1|2778266_2779385_+|integrase
MNIKSAFIRKRGEKFYVYVEYIEETTGKIKQKSYGSYEKKKDAEKHLIEIKSTINNNKFVAPKDITFVERCYKYIDMNKNNWSPYTVTSTKSWVKNYIEPFFKNLKLTEVNPSSVQAFVNYNFNNSTFTSAKVRYSFLSSVIREAYRLREIQENSCDFIKLPSKEKYSTNEIYNREEVLLLIEKLLGNNIEIPILLMLLLGLRMGEATGLRWSDVDLDNNLINVNQILVYSNGKISFKEPKTPKSKRALSAPKELIEKLKIEKLRQSKLKLQGILENKNNLVCLNTNLNPFLPSSLRKTFHNFTKKNNLKKIRIHDLRHTSATLLLLGGTNMKVVSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK
>CP012321.1|AXU61656.1|2779701_2780370_-|vanZF-protein
METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVVIFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFGEYIRLSQLGETFFNPNINLIPFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHRATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKPHSDDDSMEQDYTVCIPIAIIIVALILGFFS
>CP012321.1|AXU61657.1|2781223_2783644_-|leucyl-tRNA-synthetase
MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYPSGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTMENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCPSCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKTMQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTEYEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYGTGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLEKEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTGKGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKELVNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSKMSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLVDELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDMYKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKALVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPKKLVNIVVK
>CP012321.1|AXU61658.1|2783997_2784348_-|iojap-family-protein
MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASSQRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEKLWKDAPYIDIDTLA
>CP012321.1|AXU61659.1|2784464_2785037_-|metal-dependent-phosphohydrolase
MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAYLAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDEDIINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFNNTLMFVINKKEEIHPRTVMARNYLIKEKLL
>CP012321.1|AXU61660.1|2785037_2785727_-|nicotinate-nucleotide-adenylyltransferase
MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAHLATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEIERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPGISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYLYENKLYQYGDD
>CP012321.1|AXU61661.1|2786002_2786641_+|recombination-regulator-RecX
MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNEINEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKSYNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENAMYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI
>CP012321.1|AXU61662.1|2786793_2788797_+|glycogen-branching-protein
MKSEKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDFSSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIFIPGQNSLPHKSEIKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDNNFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPYYASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEFDGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTSMLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGMCIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCESHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLNFMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSDIFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDMVEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDNGI

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Crispr_ID: CP012321_18

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012321_18

3274851-3276987

Unclear

I-A

Consensus_repeat	Method
ATTTACATACCACTTAGTTAATATAAAAC	CRISPRCasFinder
ATTTACATACCACTTAGTTAATATAAAAC	CRT
GTTTTATATTAACTAAGTGGTATGTAAAT	PILER-CR

32 spacers

cas2,cas1,cas4,cas3,cas5,cas7,cas8b2,cas6,WYL

The CRISPR arrays of CP012321_18

>merge|CP012321|18|3274851-3276987|CRISPRCasFinder,CRT,PILER-CR
ATTTAGATATGATTTAGTTAATATAAGGTGGATGTTTTAGTATATGCTATTGTTGATTCTACAATTTTATATACTGCTTTATTAATATAAAATAAGTTTCTAAATACTCGTTGATATTGCTAATATTCTACTTATCTACCACTTAGTTGATATAAAACCTGACACTGTATCTTGTGTGAGTCTTTTCTTTATCCTATTTACATACCACTTAGTTAATATAAAACAATATTATTATAAATGGCACAGGCAACGGACAACCAAATTTACATACCACTTAGTTAATATAAAACTATCCTCCCAACAATTTTGAGGGGAGGTGATGAAGTAATTTACATACCACTTAGTTAATATAAAACAGTTTTTCAACTCTATACTTAGTCGGAATGATTGCAGATTTACATACCACTTAGTTAATATAAAACAAGCAAATGAGATTATAAAAGCTAATTCAAACAATCTTATTTACATACCACTTAGTTAATATAAAACTTCTCCGTTATATTTATCTTATTACCCTGTAATTCCTATTTACATACCACTTAGTTAATATAAAACTTTAAAAAACACTAAAATCCATAAGGGGGTGCTATTTATTTACATACCACTTAGTTAATATAAAACGCTTTTTCTTTATTAAAAAATGTTTCTAGAATATATTTATTTACATACCACTTAGTTAATATAAAACCTTGTTTTGCTGCTGAAGAGGGTGTTGCTACTGCTGTATTTACATACCACTTAGTTAATATAAAACCAGTTCCTCACCTCTTAATACACCAGAACCCAACCCTATTTACATACCACTTAGTTAATATAAAACACCAAAAGGAATGTTTATTTTTGACTTTGCTTATCAATTTACATACCACTTAGTTAATATAAAACAATAAAGCTGTAGTAAATGCCATAGATTATACACCAATTTACATACCACTTAGTTAATATAAAACTTACACTTCAAAAATTAAACTTTAGCGTACCAGATGAATTTACATACCACTTAGTTAATATAAAACTCAGAAAACTTATCACCCATAGACATCTGCATTACCAATTTACATACCACTTAGTTAATATAAAACTACACTCCCTGAGTCAGCAGTTGGTTTGTATGTTTCATTTACATACCACTTAGTTAATATAAAACCCATAGATTTTAATGTATCACCAACATTTTTAAAAATATTTACATACCACTTAGTTAATATAAAACAAGACACTACTATATCACAGCTAATAAAAAGAAAAAGGATTTACATACCACTTAGTTAATATAAAACGAAAGAACTGTTATGTATAAAAATAACTAAAAAATGGATTTACATACCACTTAGTTAATATAAAACTTAATCATAGTTCTGCAACGATAACTTTACGTTACATATTTACATACCACTTAGTTAATATAAAACTTTTAAGAATATTTTTATGCTATTTAACATAAACTAATTTACATACCACTTAGTTAATATAAAACGGAGAAGGCTTTGATAGTAATACTTTTGCCGTACCACTATTTACATACCACTTAGTTAATATAAAACTTTGAATCATTTTTATACTACTAGAATAGAAAATTAAATTTACATACCACTTAGTTAATATAAAACATTTAAAGTTCCGCACAAATAATGCTAAGTCAAAGGAATTTACATACCACTTAGTTAATATAAAACTCTCAATGAGATATAAAATAATCTTAAAGAGATTGTATTTACATACCACTTAGTTAATATAAAACCGATTTTAAATCCGGATTTGAAAGGAGGGGCTAACAAATTTACATACCACTTAGTTAATATAAAACTTCTAGTAATAAATATGAAAAATTTACATTTAATGGATTTACATACCACTTAGTTAATATAAAACCTAAGTCAAACATTATTATATAGAGCATTCTTCATTAATTTACATACCACTTAGTTAATATAAAACAAAAGAAAACAGAATCCTAACTGATTTAATAGTAAAAATTTACATACCACTTAGTTAATATAAAACTCTGTTACTGTATAAGTTTTACCATCAATTTTAGTTCCATTTACATACCACTTAGTTAATATAAAACTGGTGTGGAAAATTATTTTATCTTGAAGAAAAATCTAATTTACATACCACTTAGTTAATATAAAAC

>CP012321|18|17|3274851-3276987|CRISPRCasFinder
ATTTAGATATGATTTAGTTAATATAAGGT	GGATGTTTTAGTATATGCTATTGTTGATTCTACAA
TTTTATATACTGCTTTATTAATATAAAAT	AAGTTTCTAAATACTCGTTGATATTGCTAATATTCT
ACTTATCTACCACTTAGTTGATATAAAAC	CTGACACTGTATCTTGTGTGAGTCTTTTCTTTATCCT
ATTTACATACCACTTAGTTAATATAAAAC	AATATTATTATAAATGGCACAGGCAACGGACAACCAA
ATTTACATACCACTTAGTTAATATAAAAC	TATCCTCCCAACAATTTTGAGGGGAGGTGATGAAGTA
ATTTACATACCACTTAGTTAATATAAAAC	AGTTTTTCAACTCTATACTTAGTCGGAATGATTGCAG
ATTTACATACCACTTAGTTAATATAAAAC	AAGCAAATGAGATTATAAAAGCTAATTCAAACAATCTT
ATTTACATACCACTTAGTTAATATAAAAC	TTCTCCGTTATATTTATCTTATTACCCTGTAATTCCT
ATTTACATACCACTTAGTTAATATAAAAC	TTTAAAAAACACTAAAATCCATAAGGGGGTGCTATTT
ATTTACATACCACTTAGTTAATATAAAAC	GCTTTTTCTTTATTAAAAAATGTTTCTAGAATATATTT
ATTTACATACCACTTAGTTAATATAAAAC	CTTGTTTTGCTGCTGAAGAGGGTGTTGCTACTGCTGT
ATTTACATACCACTTAGTTAATATAAAAC	CAGTTCCTCACCTCTTAATACACCAGAACCCAACCCT
ATTTACATACCACTTAGTTAATATAAAAC	ACCAAAAGGAATGTTTATTTTTGACTTTGCTTATCA
ATTTACATACCACTTAGTTAATATAAAAC	AATAAAGCTGTAGTAAATGCCATAGATTATACACCA
ATTTACATACCACTTAGTTAATATAAAAC	TTACACTTCAAAAATTAAACTTTAGCGTACCAGATGA
ATTTACATACCACTTAGTTAATATAAAAC	TCAGAAAACTTATCACCCATAGACATCTGCATTACCA
ATTTACATACCACTTAGTTAATATAAAAC	TACACTCCCTGAGTCAGCAGTTGGTTTGTATGTTTC
ATTTACATACCACTTAGTTAATATAAAAC	CCATAGATTTTAATGTATCACCAACATTTTTAAAAAT
ATTTACATACCACTTAGTTAATATAAAAC	AAGACACTACTATATCACAGCTAATAAAAAGAAAAAGG
ATTTACATACCACTTAGTTAATATAAAAC	GAAAGAACTGTTATGTATAAAAATAACTAAAAAATGG
ATTTACATACCACTTAGTTAATATAAAAC	TTAATCATAGTTCTGCAACGATAACTTTACGTTACAT
ATTTACATACCACTTAGTTAATATAAAAC	TTTTAAGAATATTTTTATGCTATTTAACATAAACTA
ATTTACATACCACTTAGTTAATATAAAAC	GGAGAAGGCTTTGATAGTAATACTTTTGCCGTACCACT
ATTTACATACCACTTAGTTAATATAAAAC	TTTGAATCATTTTTATACTACTAGAATAGAAAATTAA
ATTTACATACCACTTAGTTAATATAAAAC	ATTTAAAGTTCCGCACAAATAATGCTAAGTCAAAGGA
ATTTACATACCACTTAGTTAATATAAAAC	TCTCAATGAGATATAAAATAATCTTAAAGAGATTGT
ATTTACATACCACTTAGTTAATATAAAAC	CGATTTTAAATCCGGATTTGAAAGGAGGGGCTAACAA
ATTTACATACCACTTAGTTAATATAAAAC	TTCTAGTAATAAATATGAAAAATTTACATTTAATGG
ATTTACATACCACTTAGTTAATATAAAAC	CTAAGTCAAACATTATTATATAGAGCATTCTTCATTA
ATTTACATACCACTTAGTTAATATAAAAC	AAAAGAAAACAGAATCCTAACTGATTTAATAGTAAAA
ATTTACATACCACTTAGTTAATATAAAAC	TCTGTTACTGTATAAGTTTTACCATCAATTTTAGTTCC
ATTTACATACCACTTAGTTAATATAAAAC	TGGTGTGGAAAATTATTTTATCTTGAAGAAAAATCTA
ATTTACATACCACTTAGTTAATATAAAAC

>CP012321|18|6|3274980-3276987|CRT
ACTTATCTACCACTTAGTTGATATAAAAC	CTGACACTGTATCTTGTGTGAGTCTTTTCTTTATCCT
ATTTACATACCACTTAGTTAATATAAAAC	AATATTATTATAAATGGCACAGGCAACGGACAACCAA
ATTTACATACCACTTAGTTAATATAAAAC	TATCCTCCCAACAATTTTGAGGGGAGGTGATGAAGTA
ATTTACATACCACTTAGTTAATATAAAAC	AGTTTTTCAACTCTATACTTAGTCGGAATGATTGCAG
ATTTACATACCACTTAGTTAATATAAAAC	AAGCAAATGAGATTATAAAAGCTAATTCAAACAATCTT
ATTTACATACCACTTAGTTAATATAAAAC	TTCTCCGTTATATTTATCTTATTACCCTGTAATTCCT
ATTTACATACCACTTAGTTAATATAAAAC	TTTAAAAAACACTAAAATCCATAAGGGGGTGCTATTT
ATTTACATACCACTTAGTTAATATAAAAC	GCTTTTTCTTTATTAAAAAATGTTTCTAGAATATATTT
ATTTACATACCACTTAGTTAATATAAAAC	CTTGTTTTGCTGCTGAAGAGGGTGTTGCTACTGCTGT
ATTTACATACCACTTAGTTAATATAAAAC	CAGTTCCTCACCTCTTAATACACCAGAACCCAACCCT
ATTTACATACCACTTAGTTAATATAAAAC	ACCAAAAGGAATGTTTATTTTTGACTTTGCTTATCA
ATTTACATACCACTTAGTTAATATAAAAC	AATAAAGCTGTAGTAAATGCCATAGATTATACACCA
ATTTACATACCACTTAGTTAATATAAAAC	TTACACTTCAAAAATTAAACTTTAGCGTACCAGATGA
ATTTACATACCACTTAGTTAATATAAAAC	TCAGAAAACTTATCACCCATAGACATCTGCATTACCA
ATTTACATACCACTTAGTTAATATAAAAC	TACACTCCCTGAGTCAGCAGTTGGTTTGTATGTTTC
ATTTACATACCACTTAGTTAATATAAAAC	CCATAGATTTTAATGTATCACCAACATTTTTAAAAAT
ATTTACATACCACTTAGTTAATATAAAAC	AAGACACTACTATATCACAGCTAATAAAAAGAAAAAGG
ATTTACATACCACTTAGTTAATATAAAAC	GAAAGAACTGTTATGTATAAAAATAACTAAAAAATGG
ATTTACATACCACTTAGTTAATATAAAAC	TTAATCATAGTTCTGCAACGATAACTTTACGTTACAT
ATTTACATACCACTTAGTTAATATAAAAC	TTTTAAGAATATTTTTATGCTATTTAACATAAACTA
ATTTACATACCACTTAGTTAATATAAAAC	GGAGAAGGCTTTGATAGTAATACTTTTGCCGTACCACT
ATTTACATACCACTTAGTTAATATAAAAC	TTTGAATCATTTTTATACTACTAGAATAGAAAATTAA
ATTTACATACCACTTAGTTAATATAAAAC	ATTTAAAGTTCCGCACAAATAATGCTAAGTCAAAGGA
ATTTACATACCACTTAGTTAATATAAAAC	TCTCAATGAGATATAAAATAATCTTAAAGAGATTGT
ATTTACATACCACTTAGTTAATATAAAAC	CGATTTTAAATCCGGATTTGAAAGGAGGGGCTAACAA
ATTTACATACCACTTAGTTAATATAAAAC	TTCTAGTAATAAATATGAAAAATTTACATTTAATGG
ATTTACATACCACTTAGTTAATATAAAAC	CTAAGTCAAACATTATTATATAGAGCATTCTTCATTA
ATTTACATACCACTTAGTTAATATAAAAC	AAAAGAAAACAGAATCCTAACTGATTTAATAGTAAAA
ATTTACATACCACTTAGTTAATATAAAAC	TCTGTTACTGTATAAGTTTTACCATCAATTTTAGTTCC
ATTTACATACCACTTAGTTAATATAAAAC	TGGTGTGGAAAATTATTTTATCTTGAAGAAAAATCTA
ATTTACATACCACTTAGTTAATATAAAAC

>CP012321|18|7|3275046-3276987|PILER-CR
ATTTACATACCACTTAGTTAATATAAAAC	AATATTATTATAAATGGCACAGGCAACGGACAACCAA
ATTTACATACCACTTAGTTAATATAAAAC	TATCCTCCCAACAATTTTGAGGGGAGGTGATGAAGTA
ATTTACATACCACTTAGTTAATATAAAAC	AGTTTTTCAACTCTATACTTAGTCGGAATGATTGCAG
ATTTACATACCACTTAGTTAATATAAAAC	AAGCAAATGAGATTATAAAAGCTAATTCAAACAATCTT
ATTTACATACCACTTAGTTAATATAAAAC	TTCTCCGTTATATTTATCTTATTACCCTGTAATTCCT
ATTTACATACCACTTAGTTAATATAAAAC	TTTAAAAAACACTAAAATCCATAAGGGGGTGCTATTT
ATTTACATACCACTTAGTTAATATAAAAC	GCTTTTTCTTTATTAAAAAATGTTTCTAGAATATATTT
ATTTACATACCACTTAGTTAATATAAAAC	CTTGTTTTGCTGCTGAAGAGGGTGTTGCTACTGCTGT
ATTTACATACCACTTAGTTAATATAAAAC	CAGTTCCTCACCTCTTAATACACCAGAACCCAACCCT
ATTTACATACCACTTAGTTAATATAAAAC	ACCAAAAGGAATGTTTATTTTTGACTTTGCTTATCA
ATTTACATACCACTTAGTTAATATAAAAC	AATAAAGCTGTAGTAAATGCCATAGATTATACACCA
ATTTACATACCACTTAGTTAATATAAAAC	TTACACTTCAAAAATTAAACTTTAGCGTACCAGATGA
ATTTACATACCACTTAGTTAATATAAAAC	TCAGAAAACTTATCACCCATAGACATCTGCATTACCA
ATTTACATACCACTTAGTTAATATAAAAC	TACACTCCCTGAGTCAGCAGTTGGTTTGTATGTTTC
ATTTACATACCACTTAGTTAATATAAAAC	CCATAGATTTTAATGTATCACCAACATTTTTAAAAAT
ATTTACATACCACTTAGTTAATATAAAAC	AAGACACTACTATATCACAGCTAATAAAAAGAAAAAGG
ATTTACATACCACTTAGTTAATATAAAAC	GAAAGAACTGTTATGTATAAAAATAACTAAAAAATGG
ATTTACATACCACTTAGTTAATATAAAAC	TTAATCATAGTTCTGCAACGATAACTTTACGTTACAT
ATTTACATACCACTTAGTTAATATAAAAC	TTTTAAGAATATTTTTATGCTATTTAACATAAACTA
ATTTACATACCACTTAGTTAATATAAAAC	GGAGAAGGCTTTGATAGTAATACTTTTGCCGTACCACT
ATTTACATACCACTTAGTTAATATAAAAC	TTTGAATCATTTTTATACTACTAGAATAGAAAATTAA
ATTTACATACCACTTAGTTAATATAAAAC	ATTTAAAGTTCCGCACAAATAATGCTAAGTCAAAGGA
ATTTACATACCACTTAGTTAATATAAAAC	TCTCAATGAGATATAAAATAATCTTAAAGAGATTGT
ATTTACATACCACTTAGTTAATATAAAAC	CGATTTTAAATCCGGATTTGAAAGGAGGGGCTAACAA
ATTTACATACCACTTAGTTAATATAAAAC	TTCTAGTAATAAATATGAAAAATTTACATTTAATGG
ATTTACATACCACTTAGTTAATATAAAAC	CTAAGTCAAACATTATTATATAGAGCATTCTTCATTA
ATTTACATACCACTTAGTTAATATAAAAC	AAAAGAAAACAGAATCCTAACTGATTTAATAGTAAAA
ATTTACATACCACTTAGTTAATATAAAAC	TCTGTTACTGTATAAGTTTTACCATCAATTTTAGTTCC
ATTTACATACCACTTAGTTAATATAAAAC	TGGTGTGGAAAATTATTTTATCTTGAAGAAAAATCTA
ATTTACATACCACTTAGTTAATATAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP012321.1\|AXU62045.1\|3268745_3269621_-\|dipicolinate-synthase-subunit-A	unknown	unknown	gnl\|CDD\|181371
CP012321.1\|AXU62044.1\|3268152_3268743_-\|dipicolinate-synthase-subunit-B	unknown	unknown	gnl\|CDD\|181370
CP012321.1\|AXU62043.1\|3267745_3267946_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU62048.1\|3272259_3272805_-\|biotin-synthase	unknown	unknown	gnl\|CDD\|376871
CP012321.1\|AXU62042.1\|3264587_3267242_-\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|237515
CP012321.1\|AXU62059.1\|3285610_3286498_-\|putative-transcriptional-regulator	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
CP012321.1\|AXU62054.1\|3278988_3281310_-\|CRISPR-associated-helicase,-Cas3-family	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|273707
CP012321.1\|AXU62053.1\|3278422_3278992_-\|CRISPR-associated-Cas4-family-protein	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
CP012321.1\|AXU62041.1\|3262091_3264311_-\|signaling-protein	unknown	unknown	gnl\|CDD\|238923
CP012321.1\|AXU62052.1\|3277439_3278420_-\|maturase-related-protein	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
CP012321.1\|AXU62047.1\|3271091_3272228_-\|thiolase	unknown	unknown	gnl\|CDD\|238383
CP012321.1\|AXU62056.1\|3282023_3282938_-\|CRISPR-associated-autoregulator,-Cst2-family	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
CP012321.1\|AXU62055.1\|3281320_3282022_-\|CRISPR-associated-protein,-Cas5t-family	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|187789
CP012321.1\|AXU62049.1\|3273128_3273908_+\|hypothetical-protein	unknown	unknown	unknown
CP012321.1\|AXU62058.1\|3284795_3285533_-\|CRISPR-associated-Cas-family-protein	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
CP012321.1\|AXU62051.1\|3277170_3277437_-\|CRISPR-associated-Cas2-family-protein	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
CP012321.1\|AXU62060.1\|3286806_3288723_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
CP012321.1\|AXU62057.1\|3282939_3284790_-\|CRISPR-associated-protein-Cas8a1/Cst1,-subtype-I-B/TNEAP	cas8b2	cd09665_cas8b2_CAS-I-B	gnl\|CDD\|313005
CP012321.1\|AXU62050.1\|3274361_3274790_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|236715
CP012321.1\|AXU62046.1\|3269696_3271088_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|341288

Protein	Function_ID	Function_description	E-value
CP012321.1\|AXU62045.1\|3268745_3269621_-\|dipicolinate-synthase-subunit-A	gnl\|CDD\|181371	PRK08306, PRK08306, dipicolinate synthase subunit DpsA.	7.6011e-131
CP012321.1\|AXU62044.1\|3268152_3268743_-\|dipicolinate-synthase-subunit-B	gnl\|CDD\|181370	PRK08305, spoVFB, dipicolinate synthase subunit B; Reviewed.	6.40655e-126
CP012321.1\|AXU62048.1\|3272259_3272805_-\|biotin-synthase	gnl\|CDD\|376871	pfam02632, BioY, BioY family. A number of bacterial genes are involved in bioconversion of pimelate into dethiobiotin. BioY is a component of the BioMNY transport system involved in biotin uptake in prokaryotes.	3.86728e-36
CP012321.1\|AXU62042.1\|3264587_3267242_-\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	gnl\|CDD\|237515	PRK13805, PRK13805, bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional.	0
CP012321.1\|AXU62059.1\|3285610_3286498_-\|putative-transcriptional-regulator	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.26937e-39
CP012321.1\|AXU62054.1\|3278988_3281310_-\|CRISPR-associated-helicase,-Cas3-family	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	3.81575e-55
CP012321.1\|AXU62041.1\|3262091_3264311_-\|signaling-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.87712e-107
CP012321.1\|AXU62052.1\|3277439_3278420_-\|maturase-related-protein	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	9.94583e-175
CP012321.1\|AXU62047.1\|3271091_3272228_-\|thiolase	gnl\|CDD\|238383	cd00751, thiolase, Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.	1.2644e-108
CP012321.1\|AXU62056.1\|3282023_3282938_-\|CRISPR-associated-autoregulator,-Cst2-family	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	2.58647e-53
CP012321.1\|AXU62055.1\|3281320_3282022_-\|CRISPR-associated-protein,-Cas5t-family	gnl\|CDD\|187789	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	4.28951e-66
CP012321.1\|AXU62051.1\|3277170_3277437_-\|CRISPR-associated-Cas2-family-protein	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.64696e-28
CP012321.1\|AXU62058.1\|3284795_3285533_-\|CRISPR-associated-Cas-family-protein	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	1.2634e-19
CP012321.1\|AXU62053.1\|3278422_3278992_-\|CRISPR-associated-Cas4-family-protein	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	4.10058e-61
CP012321.1\|AXU62060.1\|3286806_3288723_-\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	3.77497e-09
CP012321.1\|AXU62057.1\|3282939_3284790_-\|CRISPR-associated-protein-Cas8a1/Cst1,-subtype-I-B/TNEAP	gnl\|CDD\|313005	pfam09706, Cas_CXXC_CXXC, CRISPR-associated protein (Cas_CXXC_CXXC). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry describes a conserved region of about 65 amino acids from an otherwise highly divergent protein found in a minority of CRISPR-associated protein regions. This region features two motifs of CXXC.	3.11496e-21
CP012321.1\|AXU62050.1\|3274361_3274790_-\|acetyltransferase	gnl\|CDD\|236715	PRK10562, PRK10562, putative acetyltransferase; Provisional.	2.44433e-47
CP012321.1\|AXU62046.1\|3269696_3271088_-\|AMP-binding-protein	gnl\|CDD\|341288	cd17633, AFD_YhfT-like, fatty acid-CoA ligase VraA. This family of acyl-CoA ligases includes Bacillus subtilis YhfT, as well as long-chain fatty acid-CoA ligase VraA, all of which are as yet to be characterized. These proteins belong to the adenylate-forming enzymes which catalyze an ATP-dependent two-step reaction to first activate a carboxylate substrate as an adenylate and then transfer the carboxylate to the pantetheine group of either coenzyme A or an acyl-carrier protein. The active site of the domain is located at the interface of a large N-terminal subdomain and a smaller C-terminal subdomain	2.3784e-145

>CP012321.1|AXU62050.1|3274361_3274790_-|acetyltransferase
MIKKLNSKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEYIPISDTFVYDDGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATKKYKNLSLAVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK
>CP012321.1|AXU62049.1|3273128_3273908_+|hypothetical-protein
MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDEMLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYLLSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDITYKFSSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGIIAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI
>CP012321.1|AXU62048.1|3272259_3272805_-|biotin-synthase
MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIMINLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALIISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAAIFAAVVPFLIGDTIKSVIASFLGTKLNNVLRRNL
>CP012321.1|AXU62047.1|3271091_3272228_-|thiolase
MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEIDKIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQCDLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAELYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMPSILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPTSAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGHPYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV
>CP012321.1|AXU62046.1|3269696_3271088_-|AMP-binding-protein
MNYYELLRIKKERHKNKNFLIIDGEKYTYENLLSYSEELGKQISLGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISDESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKKLINYLDKSICMGALSSGSTSVPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVISSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTARNLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNTEYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDILNIGGFKVSSTKIENEVKKIPQIEDAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTSSEKIDRLALLKML
>CP012321.1|AXU62045.1|3268745_3269621_-|dipicolinate-synthase-subunit-A
MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIVGKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNIPTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGYGRCAQILAKKLYTLDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTIPECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGEILVNAIENIINERRD
>CP012321.1|AXU62044.1|3268152_3268743_-|dipicolinate-synthase-subunit-B
MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVSQNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLANGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNCKAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ
>CP012321.1|AXU62043.1|3267745_3267946_+|hypothetical-protein
MKKLKTISVFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLIMSSSFVSTTVRLIFEESKRYKF
>CP012321.1|AXU62042.1|3264587_3267242_-|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase
MAHKEQVIIENKKENEVISVGLDTVNNVESLVKKLAKIREAQKIFATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAYKETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSPHPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGMVKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLENIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPVDTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLYIDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTDTFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGGGSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKIGEKANFVAIPTSAGTGSEVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEAYVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFLGVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYVEIASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAFDDQCTGANPRYPLMNEIKDMYLNSYYGR
>CP012321.1|AXU62041.1|3262091_3264311_-|signaling-protein
MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIKEVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIVDINGNAENTKGDKFSVKDREFFKNSIKGKKYVSRPYVDEVNKSIKKIAISVPLLNNDKVVGVLYCTYNINTLMKLINISFYENNSISYVVKNDGTIILHPQGDSLSKNIYKLLEQDNDIHEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPETVVFSNSKQIINRAVYAVLSIVLIFVAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQNKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTEGEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEGEVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVYYQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCNDLSEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIQMYNLSSDFIEIEITETVAINELNILKNVLNELRKHGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSRNIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL
>CP012321.1|AXU62051.1|3277170_3277437_-|CRISPR-associated-Cas2-family-protein
MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITEGKLHKCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI
>CP012321.1|AXU62052.1|3277439_3278420_-|maturase-related-protein
MYKDYYIISNGDIKRKENTIYYYNLEGEKKILPVEQVDDIHIYGEVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERLYLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTYYKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLHEPSTKRFSLSLDIAEIFKPIIVDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFLQEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW
>CP012321.1|AXU62053.1|3278422_3278992_-|CRISPR-associated-Cas4-family-protein
MIFILTMWLKFTKEGDFVPIDLEVLKVQGVKINYYYVCKRKLWLFSKGITMEQNSSRVLSGKIVHEDSYKRMKNKEMLIDDILKLDIIKDEYVKEVKISSKMKEADEMQLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKERIIENTLININEINMQLSPPKIEKKHYCTKCAYYEFCFVKEE
>CP012321.1|AXU62054.1|3278988_3281310_-|CRISPR-associated-helicase,-Cas3-family
MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEIFWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTHLENNVGHNYLSPAFIDYSYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKVRYPIKTERLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVINIGEQTENYLMKEFGSLREAQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTLPLRVSINALFDRAKNIVGVGESNDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSCKLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKIGGRFMIMTATMSTIYIDELKKRGVMNSNLADLTCNTEKIRHCVSIVENSIDENLGKIIQSGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIKEFADSDSNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNIFIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEGTAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEELGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDLKILLYKYDIHENKHTKQIFGKGVLISNEIDQFI
>CP012321.1|AXU62055.1|3281320_3282022_-|CRISPR-associated-protein,-Cas5t-family
MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILNATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDLLEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNIRMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIGDILLDNEGDLLYFNNIN
>CP012321.1|AXU62056.1|3282023_3282938_-|CRISPR-associated-autoregulator,-Cst2-family
MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRDDGNIYTFASRQCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKDKKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGFADRIGEHPNLANIEQHLSYYTYTVTIDLSKIGKDGDIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEIANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFKGLFEDNFLSVDKFFGQLVKEVKEYYGVN
>CP012321.1|AXU62057.1|3282939_3284790_-|CRISPR-associated-protein-Cas8a1/Cst1,-subtype-I-B/TNEAP
MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSLFLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDKIKKFDEEKFNLIKEKLDSMSKIKSYDEFDSLEALVDETIDIFKIKSINDRLTANLYKYVVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNYLNDRLNSIAKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKKYMDSLEVCEMCGLYKGILDEYSESNFAPLGVSTNNARNMFWNQAYVPSICDICKLILFCTPAGATYTRKNYLINEENEFYLFVNMDTCINELFERNNSLKAQKSEYSDSKDENPFNQLIKSIVEENTLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFVKENKKIQSIYDYKLKSNVLDLILKSKDLKHLINNTLRNIVKSNLESNNKSNISGLSCFNVVQLRTILNNYKRGVYKMDYKKLRKIYESGCEIHDYYIDKNAKNKIEGITYKILNLIKVGNKNDFMQTILRIFSPSEKTPPEEILQIFVEEDLDFESVGYAFVTGLISGKYEGKDKLPNEKEEK
>CP012321.1|AXU62058.1|3284795_3285533_-|CRISPR-associated-Cas-family-protein
MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKEKNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLYKDYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNEVVKNYRGNGLKRKLEFENIGLKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDIDDLNLIYNLGIGFRRAQGFGDVDILEWR
>CP012321.1|AXU62059.1|3285610_3286498_-|putative-transcriptional-regulator
MKCKELSEELEVSERQIKSYKMYLEQAGIFINSTPGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLNTGEKSDTYMDYFTVQAQRNCDYESEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIVHPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSIGIYKGEEISVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWILSMGAYVEVVEPDRLRNDILLEIEKMKKIY
>CP012321.1|AXU62060.1|3286806_3288723_-|ABC-transporter-permease
MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDLDVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMKLIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFMILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITSTDQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKVKDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKHDSKEKDKERMMFIENNLKKENVNYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIGVKPISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVKDNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGTGKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKASTIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVRNNYLKEIRLNLVNF

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Identity
CP012321_1	1.1\|17753\|34\|CP012321\|CRISPRCasFinder	17753-17786	34	CP012321.1	32029-32062	1.0
CP012321_1	1.1\|17753\|34\|CP012321\|CRISPRCasFinder	17753-17786	34	CP012321.1	3020426-3020459	1.0
CP012321_1	1.1\|17753\|34\|CP012321\|CRISPRCasFinder	17753-17786	34	CP012321.1	3828281-3828314	1.0
CP012321_2	2.1\|132964\|39\|CP012321\|CRISPRCasFinder	132964-133002	39	CP012321.1	32024-32062	1.0
CP012321_2	2.1\|132964\|39\|CP012321\|CRISPRCasFinder	132964-133002	39	CP012321.1	3020426-3020464	1.0
CP012321_2	2.1\|132964\|39\|CP012321\|CRISPRCasFinder	132964-133002	39	CP012321.1	3828281-3828319	1.0
CP012321_3	3.1\|139848\|39\|CP012321\|CRISPRCasFinder	139848-139886	39	CP012321.1	32024-32062	1.0
CP012321_3	3.1\|139848\|39\|CP012321\|CRISPRCasFinder	139848-139886	39	CP012321.1	3020426-3020464	1.0
CP012321_3	3.1\|139848\|39\|CP012321\|CRISPRCasFinder	139848-139886	39	CP012321.1	3828281-3828319	1.0
CP012321_5	5.1\|150401\|34\|CP012321\|CRISPRCasFinder	150401-150434	34	CP012321.1	32029-32062	1.0
CP012321_5	5.1\|150401\|34\|CP012321\|CRISPRCasFinder	150401-150434	34	CP012321.1	3020426-3020459	1.0
CP012321_5	5.1\|150401\|34\|CP012321\|CRISPRCasFinder	150401-150434	34	CP012321.1	3828281-3828314	1.0

1. spacer 1.1|17753|34|CP012321|CRISPRCasFinder matches to position: 32029-32062, mismatch: 0, identity: 1.0

aaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
aaactgaacgcatgtgaagtttgtttgttggcgc	Protospacer
**********************************

2. spacer 1.1|17753|34|CP012321|CRISPRCasFinder matches to position: 3020426-3020459, mismatch: 0, identity: 1.0

aaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
aaactgaacgcatgtgaagtttgtttgttggcgc	Protospacer
**********************************

3. spacer 1.1|17753|34|CP012321|CRISPRCasFinder matches to position: 3828281-3828314, mismatch: 0, identity: 1.0

aaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
aaactgaacgcatgtgaagtttgtttgttggcgc	Protospacer
**********************************

4. spacer 2.1|132964|39|CP012321|CRISPRCasFinder matches to position: 32024-32062, mismatch: 0, identity: 1.0

agaataaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
agaataaactgaacgcatgtgaagtttgtttgttggcgc	Protospacer
***************************************

5. spacer 2.1|132964|39|CP012321|CRISPRCasFinder matches to position: 3020426-3020464, mismatch: 0, identity: 1.0

agaataaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
agaataaactgaacgcatgtgaagtttgtttgttggcgc	Protospacer
***************************************

6. spacer 2.1|132964|39|CP012321|CRISPRCasFinder matches to position: 3828281-3828319, mismatch: 0, identity: 1.0

agaataaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
agaataaactgaacgcatgtgaagtttgtttgttggcgc	Protospacer
***************************************

7. spacer 3.1|139848|39|CP012321|CRISPRCasFinder matches to position: 32024-32062, mismatch: 0, identity: 1.0

agaataaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
agaataaactgaacgcatgtgaagtttgtttgttggcgc	Protospacer
***************************************

8. spacer 3.1|139848|39|CP012321|CRISPRCasFinder matches to position: 3020426-3020464, mismatch: 0, identity: 1.0

agaataaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
agaataaactgaacgcatgtgaagtttgtttgttggcgc	Protospacer
***************************************

9. spacer 3.1|139848|39|CP012321|CRISPRCasFinder matches to position: 3828281-3828319, mismatch: 0, identity: 1.0

agaataaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
agaataaactgaacgcatgtgaagtttgtttgttggcgc	Protospacer
***************************************

10. spacer 5.1|150401|34|CP012321|CRISPRCasFinder matches to position: 32029-32062, mismatch: 0, identity: 1.0

aaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
aaactgaacgcatgtgaagtttgtttgttggcgc	Protospacer
**********************************

11. spacer 5.1|150401|34|CP012321|CRISPRCasFinder matches to position: 3020426-3020459, mismatch: 0, identity: 1.0

aaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
aaactgaacgcatgtgaagtttgtttgttggcgc	Protospacer
**********************************

12. spacer 5.1|150401|34|CP012321|CRISPRCasFinder matches to position: 3828281-3828314, mismatch: 0, identity: 1.0

aaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
aaactgaacgcatgtgaagtttgtttgttggcgc	Protospacer
**********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP012321_4	4.1\|148386\|29\|CP012321\|CRISPRCasFinder	148386-148414	29	NZ_CP033215	Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence	5105-5133	0	1.0
CP012321_7	7.1\|1548851\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548851-1548887	37	NC_028996	Clostridium phage phiCDHM19, complete genome	44931-44967	0	1.0
CP012321_7	7.1\|1548851\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548851-1548887	37	LN681542	Clostridium phage phiMMP03, complete genome	43890-43926	0	1.0
CP012321_7	7.1\|1548851\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548851-1548887	37	NC_009231	Clostridium phage phiC2, complete genome	47427-47463	0	1.0
CP012321_7	7.1\|1548851\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548851-1548887	37	NC_011398	Clostridium phage phiCD27, complete genome	42979-43015	0	1.0
CP012321_7	7.1\|1548851\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548851-1548887	37	KX228400	Clostridium phage CDKM15, complete genome	44412-44448	0	1.0
CP012321_7	7.2\|1548917\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548917-1548954	38	LN681542	Clostridium phage phiMMP03, complete genome	30418-30455	0	1.0
CP012321_7	7.2\|1548917\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548917-1548954	38	LN681541	Clostridium phage phiMMP01, complete genome	27710-27747	0	1.0
CP012321_7	7.2\|1548917\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548917-1548954	38	KX228400	Clostridium phage CDKM15, complete genome	32819-32856	0	1.0
CP012321_7	7.3\|1548984\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548984-1549020	37	MK473382	Clostridium phage JD032, complete genome	19171-19207	0	1.0
CP012321_7	7.4\|1549050\|36\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549050-1549085	36	LN681541	Clostridium phage phiMMP01, complete genome	34182-34217	0	1.0
CP012321_7	7.15\|1549779\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549779-1549816	38	NZ_MF547664	Clostridioides difficile strain LIBA-6289 plasmid LIBA6289, complete sequence	68718-68755	0	1.0
CP012321_8	8.1\|1660365\|36\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660365-1660400	36	NC_028996	Clostridium phage phiCDHM19, complete genome	43649-43684	0	1.0
CP012321_8	8.1\|1660365\|36\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660365-1660400	36	NC_011398	Clostridium phage phiCD27, complete genome	41697-41732	0	1.0
CP012321_8	8.1\|1660365\|36\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660365-1660400	36	NC_048642	Clostridium phage CDKM9, complete genome	42973-43008	0	1.0
CP012321_8	8.2\|1660430\|36\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660430-1660465	36	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	5778-5813	0	1.0
CP012321_8	8.2\|1660430\|36\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660430-1660465	36	NC_007917	Clostridium phage phi CD119, complete genome	5778-5813	0	1.0
CP012321_8	8.2\|1660430\|36\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660430-1660465	36	NC_028996	Clostridium phage phiCDHM19, complete genome	6025-6060	0	1.0
CP012321_8	8.3\|1660495\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660495-1660531	37	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	42160-42196	0	1.0
CP012321_8	8.3\|1660495\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660495-1660531	37	NC_007917	Clostridium phage phi CD119, complete genome	42160-42196	0	1.0
CP012321_8	8.3\|1660495\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660495-1660531	37	LN681539	Clostridium phage phiCD505, complete genome	42343-42379	0	1.0
CP012321_8	8.3\|1660495\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660495-1660531	37	NC_028996	Clostridium phage phiCDHM19, complete genome	45173-45209	0	1.0
CP012321_8	8.3\|1660495\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660495-1660531	37	LN681542	Clostridium phage phiMMP03, complete genome	44132-44168	0	1.0
CP012321_8	8.3\|1660495\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660495-1660531	37	HG531805	Clostridium phage CDMH1 complete genome	45495-45531	0	1.0
CP012321_8	8.3\|1660495\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660495-1660531	37	NC_009231	Clostridium phage phiC2, complete genome	47669-47705	0	1.0
CP012321_8	8.3\|1660495\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660495-1660531	37	JX145341	Clostridium phage phiMMP02, complete genome	42410-42446	0	1.0
CP012321_8	8.3\|1660495\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660495-1660531	37	NC_011398	Clostridium phage phiCD27, complete genome	43221-43257	0	1.0
CP012321_8	8.3\|1660495\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660495-1660531	37	NC_048642	Clostridium phage CDKM9, complete genome	44498-44534	0	1.0
CP012321_8	8.3\|1660495\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660495-1660531	37	KX228400	Clostridium phage CDKM15, complete genome	44654-44690	0	1.0
CP012321_8	8.5\|1660626\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660626-1660662	37	KU057941	Clostridium phage CDSH1, complete genome	30534-30570	0	1.0
CP012321_8	8.5\|1660626\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660626-1660662	37	HM568888	Clostridium phage phiCD38-2, complete genome	30026-30062	0	1.0
CP012321_8	8.5\|1660626\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660626-1660662	37	NC_028958	Clostridium phage phiCD146, complete genome	29787-29823	0	1.0
CP012321_8	8.5\|1660626\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660626-1660662	37	LN881738	Escherichia phage slur17, complete genome	31486-31522	0	1.0
CP012321_8	8.6\|1660692\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660692-1660729	38	KU057941	Clostridium phage CDSH1, complete genome	26613-26650	0	1.0
CP012321_8	8.6\|1660692\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660692-1660729	38	NC_028905	Clostridium phage phiCD111, complete genome	26387-26424	0	1.0
CP012321_8	8.6\|1660692\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660692-1660729	38	HM568888	Clostridium phage phiCD38-2, complete genome	26109-26146	0	1.0
CP012321_8	8.6\|1660692\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660692-1660729	38	NC_028958	Clostridium phage phiCD146, complete genome	25671-25708	0	1.0
CP012321_8	8.6\|1660692\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660692-1660729	38	LN881738	Escherichia phage slur17, complete genome	35406-35443	0	1.0
CP012321_9	9.1\|1722566\|37\|CP012321\|CRISPRCasFinder	1722566-1722602	37	NZ_CP029156	Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence	33197-33233	0	1.0
CP012321_9	9.1\|1722566\|37\|CP012321\|CRISPRCasFinder	1722566-1722602	37	NZ_CP029153	Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence	27241-27277	0	1.0
CP012321_9	9.1\|1722566\|37\|CP012321\|CRISPRCasFinder	1722566-1722602	37	NZ_CP020425	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence	14426-14462	0	1.0
CP012321_9	9.1\|1722566\|37\|CP012321\|CRISPRCasFinder	1722566-1722602	37	FN668942	Clostridium difficile BI1 plasmid pCDBI1, complete sequence	13071-13107	0	1.0
CP012321_9	9.1\|1722566\|37\|CP012321\|CRISPRCasFinder	1722566-1722602	37	NZ_CP011969	Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence	9748-9784	0	1.0
CP012321_10	10.1\|1834685\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834685-1834721	37	NZ_CP020425	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence	17248-17284	0	1.0
CP012321_10	10.1\|1834685\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834685-1834721	37	FN668942	Clostridium difficile BI1 plasmid pCDBI1, complete sequence	15893-15929	0	1.0
CP012321_10	10.1\|1834685\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834685-1834721	37	NZ_CP011969	Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence	12570-12606	0	1.0
CP012321_10	10.2\|1834751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834751-1834787	37	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	38446-38482	0	1.0
CP012321_10	10.2\|1834751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834751-1834787	37	NC_007917	Clostridium phage phi CD119, complete genome	38446-38482	0	1.0
CP012321_10	10.2\|1834751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834751-1834787	37	LN681542	Clostridium phage phiMMP03, complete genome	41188-41224	0	1.0
CP012321_10	10.2\|1834751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834751-1834787	37	NC_009231	Clostridium phage phiC2, complete genome	44725-44761	0	1.0
CP012321_10	10.2\|1834751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834751-1834787	37	JX145341	Clostridium phage phiMMP02, complete genome	39370-39406	0	1.0
CP012321_10	10.2\|1834751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834751-1834787	37	LN681541	Clostridium phage phiMMP01, complete genome	37487-37523	0	1.0
CP012321_10	10.2\|1834751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834751-1834787	37	KX228400	Clostridium phage CDKM15, complete genome	41710-41746	0	1.0
CP012321_10	10.3\|1834817\|36\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834817-1834852	36	NC_028996	Clostridium phage phiCDHM19, complete genome	1519-1554	0	1.0
CP012321_10	10.4\|1834882\|34\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834882-1834915	34	NC_009231	Clostridium phage phiC2, complete genome	19508-19541	0	1.0
CP012321_10	10.6\|1835011\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1835011-1835047	37	GU949551	Clostridium phage phiCD6356, complete genome	2777-2813	0	1.0
CP012321_10	10.7\|1835077\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1835077-1835113	37	GU949551	Clostridium phage phiCD6356, complete genome	10234-10270	0	1.0
CP012321_10	10.8\|1835143\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1835143-1835179	37	GU949551	Clostridium phage phiCD6356, complete genome	8720-8756	0	1.0
CP012321_10	10.11\|1835342\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1835342-1835378	37	JX145342	Clostridium phage phiMMP04, complete genome	9755-9791	0	1.0
CP012321_11	11.5\|2528925\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	2528925-2528961	37	NC_028958	Clostridium phage phiCD146, complete genome	39709-39745	0	1.0
CP012321_11	11.9\|2529187\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	2529187-2529224	38	HM568888	Clostridium phage phiCD38-2, complete genome	11366-11403	0	1.0
CP012321_11	11.9\|2529187\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	2529187-2529224	38	NC_028958	Clostridium phage phiCD146, complete genome	11375-11412	0	1.0
CP012321_11	11.12\|2529384\|36\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	2529384-2529419	36	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	49002-49037	0	1.0
CP012321_11	11.12\|2529384\|36\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	2529384-2529419	36	NC_007917	Clostridium phage phi CD119, complete genome	49002-49037	0	1.0
CP012321_11	11.12\|2529384\|36\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	2529384-2529419	36	NC_028996	Clostridium phage phiCDHM19, complete genome	50207-50242	0	1.0
CP012321_11	11.12\|2529384\|36\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	2529384-2529419	36	LN681542	Clostridium phage phiMMP03, complete genome	49546-49581	0	1.0
CP012321_11	11.12\|2529384\|36\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	2529384-2529419	36	HG531805	Clostridium phage CDMH1 complete genome	50529-50564	0	1.0
CP012321_11	11.12\|2529384\|36\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	2529384-2529419	36	NC_009231	Clostridium phage phiC2, complete genome	53084-53119	0	1.0
CP012321_13	13.7\|2775751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	2775751-2775787	37	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	39000-39036	0	1.0
CP012321_13	13.7\|2775751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	2775751-2775787	37	NC_007917	Clostridium phage phi CD119, complete genome	39000-39036	0	1.0
CP012321_13	13.8\|2775817\|35\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	2775817-2775851	35	NC_028996	Clostridium phage phiCDHM19, complete genome	31577-31611	0	1.0
CP012321_13	13.8\|2775817\|35\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	2775817-2775851	35	NC_009231	Clostridium phage phiC2, complete genome	32097-32131	0	1.0
CP012321_13	13.8\|2775817\|35\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	2775817-2775851	35	NC_011398	Clostridium phage phiCD27, complete genome	31359-31393	0	1.0
CP012321_13	13.8\|2775817\|35\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	2775817-2775851	35	NC_048642	Clostridium phage CDKM9, complete genome	30046-30080	0	1.0
CP012321_18	18.5\|3275141\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3275141-3275177	37	NC_028905	Clostridium phage phiCD111, complete genome	30693-30729	0	1.0
CP012321_18	18.18\|3275998\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3275998-3276034	37	JX145342	Clostridium phage phiMMP04, complete genome	9755-9791	0	1.0
CP012321_18	18.23\|3276328\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276328-3276365	38	GU949551	Clostridium phage phiCD6356, complete genome	17627-17664	0	1.0
CP012321_18	18.25\|3276461\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276461-3276497	37	GU949551	Clostridium phage phiCD6356, complete genome	1004-1040	0	1.0
CP012321_18	18.27\|3276592\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276592-3276628	37	GU949551	Clostridium phage phiCD6356, complete genome	3248-3284	0	1.0
CP012321_18	18.29\|3276723\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276723-3276759	37	LN681539	Clostridium phage phiCD505, complete genome	30344-30380	0	1.0
CP012321_18	18.29\|3276723\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276723-3276759	37	NC_028996	Clostridium phage phiCDHM19, complete genome	32334-32370	0	1.0
CP012321_18	18.29\|3276723\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276723-3276759	37	LN681542	Clostridium phage phiMMP03, complete genome	29323-29359	0	1.0
CP012321_18	18.29\|3276723\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276723-3276759	37	NC_009231	Clostridium phage phiC2, complete genome	32854-32890	0	1.0
CP012321_18	18.29\|3276723\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276723-3276759	37	JX145341	Clostridium phage phiMMP02, complete genome	29575-29611	0	1.0
CP012321_18	18.29\|3276723\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276723-3276759	37	LN681541	Clostridium phage phiMMP01, complete genome	26585-26621	0	1.0
CP012321_18	18.29\|3276723\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276723-3276759	37	NC_011398	Clostridium phage phiCD27, complete genome	32116-32152	0	1.0
CP012321_18	18.29\|3276723\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276723-3276759	37	NC_048642	Clostridium phage CDKM9, complete genome	30803-30839	0	1.0
CP012321_18	18.29\|3276723\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276723-3276759	37	KX228400	Clostridium phage CDKM15, complete genome	31724-31760	0	1.0
CP012321_18	18.31\|3276855\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276855-3276892	38	MK473382	Clostridium phage JD032, complete genome	22583-22620	0	1.0
CP012321_18	18.31\|3276855\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276855-3276892	38	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	18934-18971	0	1.0
CP012321_18	18.31\|3276855\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276855-3276892	38	NC_048665	Clostridium phage phiCDHM14, complete genome	12092-12129	0	1.0
CP012321_18	18.31\|3276855\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276855-3276892	38	NC_007917	Clostridium phage phi CD119, complete genome	18934-18971	0	1.0
CP012321_18	18.31\|3276855\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276855-3276892	38	NC_028996	Clostridium phage phiCDHM19, complete genome	19187-19224	0	1.0
CP012321_18	18.31\|3276855\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276855-3276892	38	JX145342	Clostridium phage phiMMP04, complete genome	12073-12110	0	1.0
CP012321_18	18.31\|3276855\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276855-3276892	38	NC_028838	Clostridium phage phiCD506, complete genome	12518-12555	0	1.0
CP012321_18	18.31\|3276855\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276855-3276892	38	HG796225	Clostridium phage phiCDHM13 complete genome	12060-12097	0	1.0
CP012321_18	18.31\|3276855\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276855-3276892	38	LN681538	Clostridium phage phiCD481-1, complete genome	12545-12582	0	1.0
CP012321_18	18.31\|3276855\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276855-3276892	38	HG798901	Clostridium phage phiCDHM11 complete genome	12059-12096	0	1.0
CP012321_18	18.32\|3276922\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276922-3276958	37	NC_011398	Clostridium phage phiCD27, complete genome	45279-45315	0	1.0
CP012321_1	1.1\|17753\|34\|CP012321\|CRISPRCasFinder	17753-17786	34	NZ_CP033215	Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence	3086-3119	1	0.971
CP012321_2	2.1\|132964\|39\|CP012321\|CRISPRCasFinder	132964-133002	39	NZ_CP033215	Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence	3086-3124	1	0.974
CP012321_3	3.1\|139848\|39\|CP012321\|CRISPRCasFinder	139848-139886	39	NZ_CP033215	Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence	3086-3124	1	0.974
CP012321_5	5.1\|150401\|34\|CP012321\|CRISPRCasFinder	150401-150434	34	NZ_CP033215	Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence	3086-3119	1	0.971
CP012321_7	7.1\|1548851\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548851-1548887	37	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	41919-41955	1	0.973
CP012321_7	7.1\|1548851\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548851-1548887	37	NC_007917	Clostridium phage phi CD119, complete genome	41919-41955	1	0.973
CP012321_7	7.2\|1548917\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548917-1548954	38	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	29403-29440	1	0.974
CP012321_7	7.2\|1548917\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548917-1548954	38	NC_007917	Clostridium phage phi CD119, complete genome	29403-29440	1	0.974
CP012321_7	7.3\|1548984\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548984-1549020	37	NC_048665	Clostridium phage phiCDHM14, complete genome	15502-15538	1	0.973
CP012321_7	7.3\|1548984\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548984-1549020	37	HG796225	Clostridium phage phiCDHM13 complete genome	15470-15506	1	0.973
CP012321_7	7.3\|1548984\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548984-1549020	37	HG798901	Clostridium phage phiCDHM11 complete genome	15469-15505	1	0.973
CP012321_7	7.14\|1549713\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549713-1549749	37	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	98082-98118	1	0.973
CP012321_7	7.14\|1549713\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549713-1549749	37	MF547662	Clostridioides phage LIBA6276, complete genome	51935-51971	1	0.973
CP012321_7	7.14\|1549713\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549713-1549749	37	MF547663	Clostridioides phage LIBA2945, complete genome	51785-51821	1	0.973
CP012321_8	8.5\|1660626\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660626-1660662	37	NC_028838	Clostridium phage phiCD506, complete genome	23956-23992	1	0.973
CP012321_8	8.5\|1660626\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660626-1660662	37	MK473382	Clostridium phage JD032, complete genome	10295-10331	1	0.973
CP012321_10	10.9\|1835209\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1835209-1835246	38	HM568888	Clostridium phage phiCD38-2, complete genome	28677-28714	1	0.974
CP012321_18	18.7\|3275273\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3275273-3275310	38	NZ_CP029156	Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence	1229-1266	1	0.974
CP012321_18	18.7\|3275273\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3275273-3275310	38	NZ_CP029153	Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence	43866-43903	1	0.974
CP012321_18	18.7\|3275273\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3275273-3275310	38	NZ_CP020425	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence	42973-43010	1	0.974
CP012321_18	18.7\|3275273\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3275273-3275310	38	FN668942	Clostridium difficile BI1 plasmid pCDBI1, complete sequence	41707-41744	1	0.974
CP012321_18	18.7\|3275273\|38\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3275273-3275310	38	NZ_CP011969	Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence	38295-38332	1	0.974
CP012321_18	18.20\|3276131\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276131-3276167	37	KU057941	Clostridium phage CDSH1, complete genome	27136-27172	1	0.973
CP012321_18	18.20\|3276131\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276131-3276167	37	NC_028905	Clostridium phage phiCD111, complete genome	26910-26946	1	0.973
CP012321_18	18.20\|3276131\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276131-3276167	37	HM568888	Clostridium phage phiCD38-2, complete genome	26632-26668	1	0.973
CP012321_18	18.20\|3276131\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276131-3276167	37	NC_028958	Clostridium phage phiCD146, complete genome	26194-26230	1	0.973
CP012321_18	18.20\|3276131\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276131-3276167	37	LN881738	Escherichia phage slur17, complete genome	34884-34920	1	0.973
CP012321_18	18.28\|3276658\|36\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276658-3276693	36	NZ_CP029156	Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence	30017-30052	1	0.972
CP012321_18	18.28\|3276658\|36\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276658-3276693	36	NZ_CP029153	Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence	24061-24096	1	0.972
CP012321_7	7.14\|1549713\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549713-1549749	37	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	76089-76125	2	0.946
CP012321_7	7.14\|1549713\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549713-1549749	37	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	45875-45911	2	0.946
CP012321_7	7.14\|1549713\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549713-1549749	37	LN681537	Clostridium phage phiCD211, complete genome	54737-54773	2	0.946
CP012321_7	7.16\|1549846\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549846-1549883	38	NC_028958	Clostridium phage phiCD146, complete genome	10891-10928	2	0.947
CP012321_8	8.3\|1660495\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660495-1660531	37	NZ_CP029156	Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence	25835-25871	2	0.946
CP012321_8	8.3\|1660495\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660495-1660531	37	NZ_CP029153	Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence	19879-19915	2	0.946
CP012321_8	8.5\|1660626\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660626-1660662	37	NC_048665	Clostridium phage phiCDHM14, complete genome	23383-23419	2	0.946
CP012321_8	8.5\|1660626\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660626-1660662	37	HG796225	Clostridium phage phiCDHM13 complete genome	22884-22920	2	0.946
CP012321_8	8.5\|1660626\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660626-1660662	37	LN681538	Clostridium phage phiCD481-1, complete genome	22623-22659	2	0.946
CP012321_8	8.5\|1660626\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660626-1660662	37	HG798901	Clostridium phage phiCDHM11 complete genome	22883-22919	2	0.946
CP012321_8	8.9\|1660893\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660893-1660929	37	NZ_MG973074	Clostridioides difficile strain HSJD-312 plasmid pHSJD-312, complete sequence	102058-102094	2	0.946
CP012321_9	9.1\|1722566\|37\|CP012321\|CRISPRCasFinder	1722566-1722602	37	KX905163	Clostridioides phage phiSemix9P1, complete genome	15609-15645	2	0.946
CP012321_10	10.3\|1834817\|36\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834817-1834852	36	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	1272-1307	2	0.944
CP012321_10	10.3\|1834817\|36\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834817-1834852	36	NC_007917	Clostridium phage phi CD119, complete genome	1272-1307	2	0.944
CP012321_11	11.1\|2528661\|36\|CP012321\|CRISPRCasFinder,CRT	2528661-2528696	36	NZ_MG973074	Clostridioides difficile strain HSJD-312 plasmid pHSJD-312, complete sequence	22132-22167	2	0.944
CP012321_11	11.12\|2529384\|36\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	2529384-2529419	36	LN681539	Clostridium phage phiCD505, complete genome	47786-47821	2	0.944
CP012321_11	11.12\|2529384\|36\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	2529384-2529419	36	NC_048642	Clostridium phage CDKM9, complete genome	48230-48265	2	0.944
CP012321_13	13.7\|2775751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	2775751-2775787	37	NC_028996	Clostridium phage phiCDHM19, complete genome	42762-42798	2	0.946
CP012321_18	18.12\|3275605\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3275605-3275641	37	LN681542	Clostridium phage phiMMP03, complete genome	14004-14040	2	0.946
CP012321_18	18.12\|3275605\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3275605-3275641	37	NC_009231	Clostridium phage phiC2, complete genome	14035-14071	2	0.946
CP012321_18	18.12\|3275605\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3275605-3275641	37	LN681541	Clostridium phage phiMMP01, complete genome	14004-14040	2	0.946
CP012321_18	18.32\|3276922\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276922-3276958	37	LN681539	Clostridium phage phiCD505, complete genome	45980-46016	2	0.946
CP012321_18	18.32\|3276922\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276922-3276958	37	LN681542	Clostridium phage phiMMP03, complete genome	47780-47816	2	0.946
CP012321_18	18.32\|3276922\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276922-3276958	37	NC_009231	Clostridium phage phiC2, complete genome	51318-51354	2	0.946
CP012321_7	7.3\|1548984\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548984-1549020	37	NZ_CP029156	Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence	30800-30836	3	0.919
CP012321_7	7.3\|1548984\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548984-1549020	37	NZ_CP029153	Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence	24844-24880	3	0.919
CP012321_7	7.16\|1549846\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549846-1549883	38	LN881738	Escherichia phage slur17, complete genome	9165-9202	3	0.921
CP012321_7	7.16\|1549846\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549846-1549883	38	KU057941	Clostridium phage CDSH1, complete genome	11235-11272	3	0.921
CP012321_7	7.16\|1549846\|38\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549846-1549883	38	NC_028905	Clostridium phage phiCD111, complete genome	11262-11299	3	0.921
CP012321_8	8.10\|1660959\|38\|CP012321\|CRISPRCasFinder,CRT	1660959-1660996	38	NZ_MG973074	Clostridioides difficile strain HSJD-312 plasmid pHSJD-312, complete sequence	94861-94898	3	0.921
CP012321_10	10.4\|1834882\|34\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1834882-1834915	34	LN681542	Clostridium phage phiMMP03, complete genome	19555-19588	3	0.912
CP012321_10	10.10\|1835276\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1835276-1835312	37	GU949551	Clostridium phage phiCD6356, complete genome	18419-18455	3	0.919
CP012321_18	18.29\|3276723\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276723-3276759	37	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	28305-28341	3	0.919
CP012321_18	18.29\|3276723\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276723-3276759	37	NC_007917	Clostridium phage phi CD119, complete genome	28305-28341	3	0.919
CP012321_18	18.29\|3276723\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276723-3276759	37	HG531805	Clostridium phage CDMH1 complete genome	28692-28728	3	0.919
CP012321_19	19.5\|3604249\|25\|CP012321\|CRT	3604249-3604273	25	MG592614	Vibrio phage 1.248.O._10N.261.54.F1, partial genome	11993-12017	3	0.88
CP012321_19	19.5\|3604249\|25\|CP012321\|CRT	3604249-3604273	25	MN693124	Marine virus AFVG_25M44, complete genome	16498-16522	3	0.88
CP012321_19	19.7\|3604348\|25\|CP012321\|CRT	3604348-3604372	25	MN693124	Marine virus AFVG_25M44, complete genome	16498-16522	3	0.88
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	KC821618	Cellulophaga phage phi10:1, complete genome	1207-1236	4	0.867
CP012321_7	7.1\|1548851\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548851-1548887	37	LN681542	Clostridium phage phiMMP03, complete genome	45043-45079	4	0.892
CP012321_7	7.1\|1548851\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548851-1548887	37	NC_009231	Clostridium phage phiC2, complete genome	48581-48617	4	0.892
CP012321_7	7.1\|1548851\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548851-1548887	37	KX228400	Clostridium phage CDKM15, complete genome	45565-45601	4	0.892
CP012321_7	7.1\|1548851\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548851-1548887	37	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	43072-43108	4	0.892
CP012321_7	7.1\|1548851\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548851-1548887	37	NC_007917	Clostridium phage phi CD119, complete genome	43072-43108	4	0.892
CP012321_7	7.1\|1548851\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548851-1548887	37	LN681539	Clostridium phage phiCD505, complete genome	43254-43290	4	0.892
CP012321_7	7.1\|1548851\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548851-1548887	37	JX145341	Clostridium phage phiMMP02, complete genome	43321-43357	4	0.892
CP012321_8	8.5\|1660626\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1660626-1660662	37	NC_028905	Clostridium phage phiCD111, complete genome	30329-30365	4	0.892
CP012321_19	19.5\|3604249\|25\|CP012321\|CRT	3604249-3604273	25	MG592608	Vibrio phage 1.243.O._10N.261.54.B5, partial genome	11272-11296	4	0.84
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP045692	Klebsiella pneumoniae strain TK421 plasmid pTK421_2, complete sequence	78485-78514	5	0.833
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP042421	Leuconostoc lactis strain CBA3622 plasmid unnamed1, complete sequence	41155-41184	5	0.833
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	30253-30282	5	0.833
CP012321_4	4.1\|148386\|29\|CP012321\|CRISPRCasFinder	148386-148414	29	KY971610	Pseudomonas phage PspYZU05, complete genome	134239-134267	6	0.793
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP009068	Borreliella afzelii K78 plasmid cp32-9, complete sequence	17310-17339	6	0.8
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP009069	Borreliella afzelii K78 plasmid cp32-4, complete sequence	17206-17235	6	0.8
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NC_015917	Borreliella bissettii DN127 plasmid lp28-4, complete sequence	20571-20600	6	0.8
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	1306356-1306385	6	0.8
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	72809-72838	6	0.8
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP030264	Ensifer adhaerens strain Corn53 plasmid AB, complete sequence	1114535-1114564	6	0.8
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP042215	Enterococcus faecalis strain L15 plasmid pL15-A, complete sequence	17519-17548	6	0.8
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	CP040041	Acinetobacter baumannii strain VB958 plasmid unnamed1, complete sequence	30325-30354	6	0.8
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	CP016195	Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-1, complete sequence	182637-182666	7	0.767
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	MN693725	Marine virus AFVG_250M494, complete genome	7495-7524	7	0.767
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP017230	Campylobacter jejuni strain FORC_046 isolate Not reported plasmid pFORC46.1, complete sequence	20957-20986	7	0.767
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NC_017577	Shewanella baltica OS117 plasmid pSBAL11701, complete sequence	108731-108760	7	0.767
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	357630-357659	7	0.767
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP014203	Clostridium baratii strain CDC51267 plasmid pNPD11_1, complete sequence	111331-111360	7	0.767
CP012321_7	7.7\|1549249\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549249-1549285	37	MN694790	Marine virus AFVG_250M551, complete genome	17976-18012	7	0.811
CP012321_13	13.7\|2775751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	2775751-2775787	37	NC_048642	Clostridium phage CDKM9, complete genome	42091-42127	7	0.811
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP006906	Clostridium baratii str. Sullivan plasmid pCBJ, complete sequence	75812-75841	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	MN693547	Marine virus AFVG_25M424, complete genome	13091-13120	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	MN693297	Marine virus AFVG_25M423, complete genome	9184-9213	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP006570	Sodalis praecaptivus strain HS1 plasmid pHS1, complete sequence	274006-274035	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	AP014396	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S46-C203, * SEQUENCING IN PROGRESS *	2835-2864	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	MN693353	Marine virus AFVG_25M425, complete genome	17638-17667	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP028373	Campylobacter jejuni subsp. jejuni strain huA17 plasmid unnamed1, complete sequence	71028-71057	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP028373	Campylobacter jejuni subsp. jejuni strain huA17 plasmid unnamed1, complete sequence	72280-72309	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	AP022644	Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence	88412-88441	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_LR214999	Mycoplasma conjunctivae strain NCTC10147 plasmid 3	47192-47221	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	LR214965	Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 11	36784-36813	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP014745	Campylobacter jejuni strain OD267 plasmid pCJDM67 L, complete sequence	113566-113595	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	CP024686	Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-2-313K, complete sequence	34948-34977	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP014345	Campylobacter jejuni strain RM3194 plasmid unnamed, complete sequence	54090-54119	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP014345	Campylobacter jejuni strain RM3194 plasmid unnamed, complete sequence	55342-55371	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP014743	Campylobacter jejuni strain WP2202 plasmid pCJDM202, complete sequence	116226-116255	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP017417	Campylobacter jejuni strain MTVDSCj13 plasmid pMTVDSCj13-2, complete sequence	28139-28168	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_LR134420	Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 11	60920-60949	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP044174	Campylobacter jejuni strain AR-0412 plasmid pAR-0412, complete sequence	10352-10381	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	MK448965	Streptococcus phage Javan506, complete genome	13313-13342	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NC_007581	Clostridium phage c-st, complete genome	13365-13394	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	MK448959	Streptococcus phage Javan488, complete genome	13313-13342	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	MK448686	Streptococcus phage Javan157, complete genome	12914-12943	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	MK448949	Streptococcus phage Javan460, complete genome	13313-13342	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	MK448951	Streptococcus phage Javan470, complete genome	12914-12943	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	MK448676	Streptococcus phage Javan131, complete genome	14779-14808	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	AP008983	Clostridium phage c-st genomic DNA, complete genome	13365-13394	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP043762	Paenibacillus sp. 37 plasmid pART37, complete sequence	6554-6583	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP019232	Bacillus thuringiensis strain YGd22-03 plasmid pYGD36, complete sequence	3173-3202	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP010112	Bacillus thuringiensis serovar indiana strain HD521 plasmid pBTHD521-6, complete sequence	199881-199910	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	134417-134446	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	CP012553	Campylobacter sp. RM16192 plasmid p16192, complete sequence	15672-15701	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	KY554775	Lactococcus phage AM11, complete genome	20566-20595	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	KY554773	Lactococcus phage AM8, complete genome	20565-20594	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	KY554768	Lactococcus phage AM1, complete genome	20565-20594	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	KY554769	Lactococcus phage AM2, complete genome	20565-20594	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	KY554770	Lactococcus phage AM3, complete genome	20567-20596	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	MN694408	Marine virus AFVG_250M293, complete genome	5785-5814	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	KY554776	Lactococcus phage AM12, complete genome	20547-20576	8	0.733
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	KY554774	Lactococcus phage AM9, complete genome	20565-20594	8	0.733
CP012321_7	7.3\|1548984\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548984-1549020	37	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	22355-22391	8	0.784
CP012321_7	7.3\|1548984\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1548984-1549020	37	NC_007917	Clostridium phage phi CD119, complete genome	22355-22391	8	0.784
CP012321_11	11.3\|2528793\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	2528793-2528829	37	CP000313	Clostridium perfringens SM101 plasmid pSM101A, complete sequence	9758-9794	8	0.784
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP004877	Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMB431, complete sequence	64826-64855	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP004860	Bacillus thuringiensis serovar kurstaki str. YBT-1520 plasmid pBMB422, complete sequence	85077-85106	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP011156	Bacillus cereus strain HN001 plasmid pRML01, complete sequence	234555-234584	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP010090	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB426, complete sequence	68597-68626	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	AP013426	Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C57-MedDCM-OCT-S27-C24	23413-23442	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	KJ535721	Listeria phage List-36, complete genome	131839-131868	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP014283	Bacillus thuringiensis strain Bt185 plasmid pBT1850636, complete sequence	430237-430266	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP033461	Brevibacillus laterosporus strain 1821L plasmid p1821L01, complete sequence	7252-7281	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP011350	Bacillus thuringiensis strain YC-10 plasmid pYC1, complete sequence	190785-190814	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP032614	Bacillus thuringiensis strain QZL38 plasmid p.1, complete sequence	119421-119450	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP007616	Bacillus thuringiensis serovar kurstaki str. YBT-1520 plasmid pBMB400, complete sequence	293348-293377	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NC_002253	Buchnera aphidicola str. APS (Acyrthosiphon pisum) plasmid pLeu, complete sequence	2039-2068	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP023246	Bacillus cereus strain HBL-AI plasmid unnamed1, complete sequence	252793-252822	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP048772	Campylobacter jejuni strain ZS007 plasmid pCJ145K, complete sequence	129793-129822	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP048772	Campylobacter jejuni strain ZS007 plasmid pCJ145K, complete sequence	131046-131075	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	MN172529	Listeria phage LP-039, complete genome	130877-130906	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	DQ003638	Listeria phage A511, complete genome	132156-132185	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	KJ591604	Listeria phage LMTA-148, complete genome	7271-7300	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	KJ094033	Listeria phage LP-048, complete genome	305-334	9	0.7
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	JQ797329	Listeria phage vB_LmoM_AG20, complete genome	130913-130942	9	0.7
CP012321_7	7.7\|1549249\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549249-1549285	37	GU949551	Clostridium phage phiCD6356, complete genome	33206-33242	9	0.757
CP012321_9	9.1\|1722566\|37\|CP012321\|CRISPRCasFinder	1722566-1722602	37	NZ_CP011156	Bacillus cereus strain HN001 plasmid pRML01, complete sequence	286293-286329	9	0.757
CP012321_18	18.28\|3276658\|36\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276658-3276693	36	NZ_CP013044	Clostridium perfringens strain JP55 plasmid pJFP55J, complete sequence	37904-37939	9	0.75
CP012321_18	18.28\|3276658\|36\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276658-3276693	36	NZ_MK275624	Clostridium perfringens strain JXJA17 plasmid p6, complete sequence	1000-1035	9	0.75
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	KJ018210	Flavobacterium sp. phage 1/32, complete genome	7455-7484	10	0.667
CP012321_7	7.12\|1549579\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	1549579-1549615	37	MN855790	Bacteriophage sp. isolate 76, complete genome	20852-20888	10	0.73
CP012321_11	11.1\|2528661\|36\|CP012321\|CRISPRCasFinder,CRT	2528661-2528696	36	NZ_CP045274	Bacillus megaterium strain FDU301 plasmid pFDU301B, complete sequence	47033-47068	10	0.722
CP012321_13	13.7\|2775751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	2775751-2775787	37	GU949551	Clostridium phage phiCD6356, complete genome	31136-31172	10	0.73
CP012321_13	13.7\|2775751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	2775751-2775787	37	NZ_CP019601	Brachyspira hyodysenteriae strain BH718 plasmid pBH718, complete sequence	15929-15965	10	0.73
CP012321_13	13.7\|2775751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	2775751-2775787	37	NC_012226	Brachyspira hyodysenteriae WA1 plasmid pBHWA1, complete sequence	21941-21977	10	0.73
CP012321_13	13.7\|2775751\|37\|CP012321\|PILER-CR,CRISPRCasFinder,CRT	2775751-2775787	37	NZ_CP016085	Brachyspira hyodysenteriae ATCC 27164 strain B-78 plasmid pBhyoB78, complete sequence	4001-4037	10	0.73
CP012321_14	14.1\|3007474\|34\|CP012321\|CRISPRCasFinder	3007474-3007507	34	MN856057	Bacteriophage sp. isolate 161, complete genome	9470-9503	10	0.706
CP012321_14	14.1\|3007474\|34\|CP012321\|CRISPRCasFinder	3007474-3007507	34	MN855979	Bacteriophage sp. isolate 144, complete genome	12547-12580	10	0.706
CP012321_18	18.28\|3276658\|36\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276658-3276693	36	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	247502-247537	10	0.722
CP012321_19	19.9\|3604438\|34\|CP012321\|CRT	3604438-3604471	34	KT151959	Brevibacillus phage Sundance, complete genome	46329-46362	10	0.706
CP012321_14	14.1\|3007474\|34\|CP012321\|CRISPRCasFinder	3007474-3007507	34	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	547093-547126	11	0.676
CP012321_18	18.32\|3276922\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276922-3276958	37	CP016281	Clostridium tyrobutyricum strain W428 plasmid pW428, complete sequence	57520-57556	13	0.649
CP012321_18	18.32\|3276922\|37\|CP012321\|CRISPRCasFinder,CRT,PILER-CR	3276922-3276958	37	NZ_CP014171	Clostridium tyrobutyricum strain KCTC 5387 plasmid pCTK01, complete sequence	42044-42080	13	0.649
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP011156	Bacillus cereus strain HN001 plasmid pRML01, complete sequence	429045-429074	16	0.467
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP040783	Bacillus thuringiensis strain HM-311 plasmid p1, complete sequence	410674-410703	16	0.467
CP012321_6	6.1\|1076578\|30\|CP012321\|CRISPRCasFinder	1076578-1076607	30	NZ_CP014283	Bacillus thuringiensis strain Bt185 plasmid pBT1850636, complete sequence	141205-141234	16	0.467

1. spacer 4.1|148386|29|CP012321|CRISPRCasFinder matches to NZ_CP033215 (Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

tgtaataagttaaagcaatatgaatcaac	CRISPR spacer
tgtaataagttaaagcaatatgaatcaac	Protospacer
*****************************

2. spacer 7.1|1548851|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 0, identity: 1.0

tattttcatttttgagagttacaaaacatctcaatga	CRISPR spacer
tattttcatttttgagagttacaaaacatctcaatga	Protospacer
*************************************

3. spacer 7.1|1548851|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 0, identity: 1.0

tattttcatttttgagagttacaaaacatctcaatga	CRISPR spacer
tattttcatttttgagagttacaaaacatctcaatga	Protospacer
*************************************

4. spacer 7.1|1548851|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 0, identity: 1.0

tattttcatttttgagagttacaaaacatctcaatga	CRISPR spacer
tattttcatttttgagagttacaaaacatctcaatga	Protospacer
*************************************

5. spacer 7.1|1548851|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 0, identity: 1.0

tattttcatttttgagagttacaaaacatctcaatga	CRISPR spacer
tattttcatttttgagagttacaaaacatctcaatga	Protospacer
*************************************

6. spacer 7.1|1548851|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to KX228400 (Clostridium phage CDKM15, complete genome) position: , mismatch: 0, identity: 1.0

tattttcatttttgagagttacaaaacatctcaatga	CRISPR spacer
tattttcatttttgagagttacaaaacatctcaatga	Protospacer
*************************************

7. spacer 7.2|1548917|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 0, identity: 1.0

taaattcgtctaacttaaattaataataggagcttttt	CRISPR spacer
taaattcgtctaacttaaattaataataggagcttttt	Protospacer
**************************************

8. spacer 7.2|1548917|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 0, identity: 1.0

taaattcgtctaacttaaattaataataggagcttttt	CRISPR spacer
taaattcgtctaacttaaattaataataggagcttttt	Protospacer
**************************************

9. spacer 7.2|1548917|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to KX228400 (Clostridium phage CDKM15, complete genome) position: , mismatch: 0, identity: 1.0

taaattcgtctaacttaaattaataataggagcttttt	CRISPR spacer
taaattcgtctaacttaaattaataataggagcttttt	Protospacer
**************************************

10. spacer 7.3|1548984|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 0, identity: 1.0

acagttgtattagcaactttaaaagatatacaagact	CRISPR spacer
acagttgtattagcaactttaaaagatatacaagact	Protospacer
*************************************

11. spacer 7.4|1549050|36|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 0, identity: 1.0

ttatttttaagtcaacactcttttgagttggtgtat	CRISPR spacer
ttatttttaagtcaacactcttttgagttggtgtat	Protospacer
************************************

12. spacer 7.15|1549779|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MF547664 (Clostridioides difficile strain LIBA-6289 plasmid LIBA6289, complete sequence) position: , mismatch: 0, identity: 1.0

atcttttaatttttataactaactatttacaaattcaa	CRISPR spacer
atcttttaatttttataactaactatttacaaattcaa	Protospacer
**************************************

13. spacer 8.1|1660365|36|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 0, identity: 1.0

tggaatttaaaggcagaaggaacagctacagtgacg	CRISPR spacer
tggaatttaaaggcagaaggaacagctacagtgacg	Protospacer
************************************

14. spacer 8.1|1660365|36|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 0, identity: 1.0

tggaatttaaaggcagaaggaacagctacagtgacg	CRISPR spacer
tggaatttaaaggcagaaggaacagctacagtgacg	Protospacer
************************************

15. spacer 8.1|1660365|36|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 0, identity: 1.0

tggaatttaaaggcagaaggaacagctacagtgacg	CRISPR spacer
tggaatttaaaggcagaaggaacagctacagtgacg	Protospacer
************************************

16. spacer 8.2|1660430|36|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

acattaacattagcaacacaattaataacgatttgt	CRISPR spacer
acattaacattagcaacacaattaataacgatttgt	Protospacer
************************************

17. spacer 8.2|1660430|36|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

acattaacattagcaacacaattaataacgatttgt	CRISPR spacer
acattaacattagcaacacaattaataacgatttgt	Protospacer
************************************

18. spacer 8.2|1660430|36|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 0, identity: 1.0

acattaacattagcaacacaattaataacgatttgt	CRISPR spacer
acattaacattagcaacacaattaataacgatttgt	Protospacer
************************************

19. spacer 8.3|1660495|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

agagcagatgtctggtgttttggattcccatgtcaag	CRISPR spacer
agagcagatgtctggtgttttggattcccatgtcaag	Protospacer
*************************************

20. spacer 8.3|1660495|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

agagcagatgtctggtgttttggattcccatgtcaag	CRISPR spacer
agagcagatgtctggtgttttggattcccatgtcaag	Protospacer
*************************************

21. spacer 8.3|1660495|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 0, identity: 1.0

agagcagatgtctggtgttttggattcccatgtcaag	CRISPR spacer
agagcagatgtctggtgttttggattcccatgtcaag	Protospacer
*************************************

22. spacer 8.3|1660495|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 0, identity: 1.0

agagcagatgtctggtgttttggattcccatgtcaag	CRISPR spacer
agagcagatgtctggtgttttggattcccatgtcaag	Protospacer
*************************************

23. spacer 8.3|1660495|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 0, identity: 1.0

agagcagatgtctggtgttttggattcccatgtcaag	CRISPR spacer
agagcagatgtctggtgttttggattcccatgtcaag	Protospacer
*************************************

24. spacer 8.3|1660495|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 0, identity: 1.0

agagcagatgtctggtgttttggattcccatgtcaag	CRISPR spacer
agagcagatgtctggtgttttggattcccatgtcaag	Protospacer
*************************************

25. spacer 8.3|1660495|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 0, identity: 1.0

agagcagatgtctggtgttttggattcccatgtcaag	CRISPR spacer
agagcagatgtctggtgttttggattcccatgtcaag	Protospacer
*************************************

26. spacer 8.3|1660495|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 0, identity: 1.0

agagcagatgtctggtgttttggattcccatgtcaag	CRISPR spacer
agagcagatgtctggtgttttggattcccatgtcaag	Protospacer
*************************************

27. spacer 8.3|1660495|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 0, identity: 1.0

agagcagatgtctggtgttttggattcccatgtcaag	CRISPR spacer
agagcagatgtctggtgttttggattcccatgtcaag	Protospacer
*************************************

28. spacer 8.3|1660495|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 0, identity: 1.0

agagcagatgtctggtgttttggattcccatgtcaag	CRISPR spacer
agagcagatgtctggtgttttggattcccatgtcaag	Protospacer
*************************************

29. spacer 8.3|1660495|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to KX228400 (Clostridium phage CDKM15, complete genome) position: , mismatch: 0, identity: 1.0

agagcagatgtctggtgttttggattcccatgtcaag	CRISPR spacer
agagcagatgtctggtgttttggattcccatgtcaag	Protospacer
*************************************

30. spacer 8.5|1660626|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to KU057941 (Clostridium phage CDSH1, complete genome) position: , mismatch: 0, identity: 1.0

ataagagtggtttaagaaaataagttatttttcaaaa	CRISPR spacer
ataagagtggtttaagaaaataagttatttttcaaaa	Protospacer
*************************************

31. spacer 8.5|1660626|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to HM568888 (Clostridium phage phiCD38-2, complete genome) position: , mismatch: 0, identity: 1.0

ataagagtggtttaagaaaataagttatttttcaaaa	CRISPR spacer
ataagagtggtttaagaaaataagttatttttcaaaa	Protospacer
*************************************

32. spacer 8.5|1660626|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_028958 (Clostridium phage phiCD146, complete genome) position: , mismatch: 0, identity: 1.0

ataagagtggtttaagaaaataagttatttttcaaaa	CRISPR spacer
ataagagtggtttaagaaaataagttatttttcaaaa	Protospacer
*************************************

33. spacer 8.5|1660626|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN881738 (Escherichia phage slur17, complete genome) position: , mismatch: 0, identity: 1.0

ataagagtggtttaagaaaataagttatttttcaaaa	CRISPR spacer
ataagagtggtttaagaaaataagttatttttcaaaa	Protospacer
*************************************

34. spacer 8.6|1660692|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to KU057941 (Clostridium phage CDSH1, complete genome) position: , mismatch: 0, identity: 1.0

tcgaatgctataattttaatatataaaataaatggagg	CRISPR spacer
tcgaatgctataattttaatatataaaataaatggagg	Protospacer
**************************************

35. spacer 8.6|1660692|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_028905 (Clostridium phage phiCD111, complete genome) position: , mismatch: 0, identity: 1.0

tcgaatgctataattttaatatataaaataaatggagg	CRISPR spacer
tcgaatgctataattttaatatataaaataaatggagg	Protospacer
**************************************

36. spacer 8.6|1660692|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to HM568888 (Clostridium phage phiCD38-2, complete genome) position: , mismatch: 0, identity: 1.0

tcgaatgctataattttaatatataaaataaatggagg	CRISPR spacer
tcgaatgctataattttaatatataaaataaatggagg	Protospacer
**************************************

37. spacer 8.6|1660692|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_028958 (Clostridium phage phiCD146, complete genome) position: , mismatch: 0, identity: 1.0

tcgaatgctataattttaatatataaaataaatggagg	CRISPR spacer
tcgaatgctataattttaatatataaaataaatggagg	Protospacer
**************************************

38. spacer 8.6|1660692|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN881738 (Escherichia phage slur17, complete genome) position: , mismatch: 0, identity: 1.0

tcgaatgctataattttaatatataaaataaatggagg	CRISPR spacer
tcgaatgctataattttaatatataaaataaatggagg	Protospacer
**************************************

39. spacer 9.1|1722566|37|CP012321|CRISPRCasFinder matches to NZ_CP029156 (Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

ctttaaaatagttgaaagaaatgaagcaattaaagta	CRISPR spacer
ctttaaaatagttgaaagaaatgaagcaattaaagta	Protospacer
*************************************

40. spacer 9.1|1722566|37|CP012321|CRISPRCasFinder matches to NZ_CP029153 (Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ctttaaaatagttgaaagaaatgaagcaattaaagta	CRISPR spacer
ctttaaaatagttgaaagaaatgaagcaattaaagta	Protospacer
*************************************

41. spacer 9.1|1722566|37|CP012321|CRISPRCasFinder matches to NZ_CP020425 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ctttaaaatagttgaaagaaatgaagcaattaaagta	CRISPR spacer
ctttaaaatagttgaaagaaatgaagcaattaaagta	Protospacer
*************************************

42. spacer 9.1|1722566|37|CP012321|CRISPRCasFinder matches to FN668942 (Clostridium difficile BI1 plasmid pCDBI1, complete sequence) position: , mismatch: 0, identity: 1.0

ctttaaaatagttgaaagaaatgaagcaattaaagta	CRISPR spacer
ctttaaaatagttgaaagaaatgaagcaattaaagta	Protospacer
*************************************

43. spacer 9.1|1722566|37|CP012321|CRISPRCasFinder matches to NZ_CP011969 (Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

ctttaaaatagttgaaagaaatgaagcaattaaagta	CRISPR spacer
ctttaaaatagttgaaagaaatgaagcaattaaagta	Protospacer
*************************************

44. spacer 10.1|1834685|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020425 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

tcgttataagtaagacgtgaagcatgaatatctgtca	CRISPR spacer
tcgttataagtaagacgtgaagcatgaatatctgtca	Protospacer
*************************************

45. spacer 10.1|1834685|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to FN668942 (Clostridium difficile BI1 plasmid pCDBI1, complete sequence) position: , mismatch: 0, identity: 1.0

tcgttataagtaagacgtgaagcatgaatatctgtca	CRISPR spacer
tcgttataagtaagacgtgaagcatgaatatctgtca	Protospacer
*************************************

46. spacer 10.1|1834685|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011969 (Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

tcgttataagtaagacgtgaagcatgaatatctgtca	CRISPR spacer
tcgttataagtaagacgtgaagcatgaatatctgtca	Protospacer
*************************************

47. spacer 10.2|1834751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

cttgaaaatcctcagaagctaaaatcccgaaaaactg	CRISPR spacer
cttgaaaatcctcagaagctaaaatcccgaaaaactg	Protospacer
*************************************

48. spacer 10.2|1834751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

cttgaaaatcctcagaagctaaaatcccgaaaaactg	CRISPR spacer
cttgaaaatcctcagaagctaaaatcccgaaaaactg	Protospacer
*************************************

49. spacer 10.2|1834751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 0, identity: 1.0

cttgaaaatcctcagaagctaaaatcccgaaaaactg	CRISPR spacer
cttgaaaatcctcagaagctaaaatcccgaaaaactg	Protospacer
*************************************

50. spacer 10.2|1834751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 0, identity: 1.0

cttgaaaatcctcagaagctaaaatcccgaaaaactg	CRISPR spacer
cttgaaaatcctcagaagctaaaatcccgaaaaactg	Protospacer
*************************************

51. spacer 10.2|1834751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 0, identity: 1.0

cttgaaaatcctcagaagctaaaatcccgaaaaactg	CRISPR spacer
cttgaaaatcctcagaagctaaaatcccgaaaaactg	Protospacer
*************************************

52. spacer 10.2|1834751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 0, identity: 1.0

cttgaaaatcctcagaagctaaaatcccgaaaaactg	CRISPR spacer
cttgaaaatcctcagaagctaaaatcccgaaaaactg	Protospacer
*************************************

53. spacer 10.2|1834751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to KX228400 (Clostridium phage CDKM15, complete genome) position: , mismatch: 0, identity: 1.0

cttgaaaatcctcagaagctaaaatcccgaaaaactg	CRISPR spacer
cttgaaaatcctcagaagctaaaatcccgaaaaactg	Protospacer
*************************************

54. spacer 10.3|1834817|36|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 0, identity: 1.0

ccactattactttctatgtcagctttgttaacttcg	CRISPR spacer
ccactattactttctatgtcagctttgttaacttcg	Protospacer
************************************

55. spacer 10.4|1834882|34|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 0, identity: 1.0

aaattcacagagctttggtgggaatatacaaaac	CRISPR spacer
aaattcacagagctttggtgggaatatacaaaac	Protospacer
**********************************

56. spacer 10.6|1835011|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to GU949551 (Clostridium phage phiCD6356, complete genome) position: , mismatch: 0, identity: 1.0

ttcgaaagcggtaaaacagcattatcactttcaaaat	CRISPR spacer
ttcgaaagcggtaaaacagcattatcactttcaaaat	Protospacer
*************************************

57. spacer 10.7|1835077|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to GU949551 (Clostridium phage phiCD6356, complete genome) position: , mismatch: 0, identity: 1.0

ctgctaatcctgctattttaactatagtttctaccgt	CRISPR spacer
ctgctaatcctgctattttaactatagtttctaccgt	Protospacer
*************************************

58. spacer 10.8|1835143|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to GU949551 (Clostridium phage phiCD6356, complete genome) position: , mismatch: 0, identity: 1.0

tcaagacttgttccaaaatttttcactccagcgccag	CRISPR spacer
tcaagacttgttccaaaatttttcactccagcgccag	Protospacer
*************************************

59. spacer 10.11|1835342|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to JX145342 (Clostridium phage phiMMP04, complete genome) position: , mismatch: 0, identity: 1.0

atttttaaaaatgttggtgatacattaaaatctatgg	CRISPR spacer
atttttaaaaatgttggtgatacattaaaatctatgg	Protospacer
*************************************

60. spacer 11.5|2528925|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_028958 (Clostridium phage phiCD146, complete genome) position: , mismatch: 0, identity: 1.0

aaatggaggaatagaagtgaaagagaaagttaagcgc	CRISPR spacer
aaatggaggaatagaagtgaaagagaaagttaagcgc	Protospacer
*************************************

61. spacer 11.9|2529187|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to HM568888 (Clostridium phage phiCD38-2, complete genome) position: , mismatch: 0, identity: 1.0

caatcaagttataagactcttttgcgctaaccccaaac	CRISPR spacer
caatcaagttataagactcttttgcgctaaccccaaac	Protospacer
**************************************

62. spacer 11.9|2529187|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_028958 (Clostridium phage phiCD146, complete genome) position: , mismatch: 0, identity: 1.0

caatcaagttataagactcttttgcgctaaccccaaac	CRISPR spacer
caatcaagttataagactcttttgcgctaaccccaaac	Protospacer
**************************************

63. spacer 11.12|2529384|36|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

gagatattactagattgaaaaaactgaaaaaagata	CRISPR spacer
gagatattactagattgaaaaaactgaaaaaagata	Protospacer
************************************

64. spacer 11.12|2529384|36|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

gagatattactagattgaaaaaactgaaaaaagata	CRISPR spacer
gagatattactagattgaaaaaactgaaaaaagata	Protospacer
************************************

65. spacer 11.12|2529384|36|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 0, identity: 1.0

gagatattactagattgaaaaaactgaaaaaagata	CRISPR spacer
gagatattactagattgaaaaaactgaaaaaagata	Protospacer
************************************

66. spacer 11.12|2529384|36|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 0, identity: 1.0

gagatattactagattgaaaaaactgaaaaaagata	CRISPR spacer
gagatattactagattgaaaaaactgaaaaaagata	Protospacer
************************************

67. spacer 11.12|2529384|36|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 0, identity: 1.0

gagatattactagattgaaaaaactgaaaaaagata	CRISPR spacer
gagatattactagattgaaaaaactgaaaaaagata	Protospacer
************************************

68. spacer 11.12|2529384|36|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 0, identity: 1.0

gagatattactagattgaaaaaactgaaaaaagata	CRISPR spacer
gagatattactagattgaaaaaactgaaaaaagata	Protospacer
************************************

69. spacer 13.7|2775751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

aagtcaaaaggttaaatttaaataaaattatacttct	CRISPR spacer
aagtcaaaaggttaaatttaaataaaattatacttct	Protospacer
*************************************

70. spacer 13.7|2775751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

aagtcaaaaggttaaatttaaataaaattatacttct	CRISPR spacer
aagtcaaaaggttaaatttaaataaaattatacttct	Protospacer
*************************************

71. spacer 13.8|2775817|35|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 0, identity: 1.0

ccaatagtaaatataaatcaagttgttgatgcttt	CRISPR spacer
ccaatagtaaatataaatcaagttgttgatgcttt	Protospacer
***********************************

72. spacer 13.8|2775817|35|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 0, identity: 1.0

ccaatagtaaatataaatcaagttgttgatgcttt	CRISPR spacer
ccaatagtaaatataaatcaagttgttgatgcttt	Protospacer
***********************************

73. spacer 13.8|2775817|35|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 0, identity: 1.0

ccaatagtaaatataaatcaagttgttgatgcttt	CRISPR spacer
ccaatagtaaatataaatcaagttgttgatgcttt	Protospacer
***********************************

74. spacer 13.8|2775817|35|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 0, identity: 1.0

ccaatagtaaatataaatcaagttgttgatgcttt	CRISPR spacer
ccaatagtaaatataaatcaagttgttgatgcttt	Protospacer
***********************************

75. spacer 18.5|3275141|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_028905 (Clostridium phage phiCD111, complete genome) position: , mismatch: 0, identity: 1.0

tatcctcccaacaattttgaggggaggtgatgaagta	CRISPR spacer
tatcctcccaacaattttgaggggaggtgatgaagta	Protospacer
*************************************

76. spacer 18.18|3275998|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to JX145342 (Clostridium phage phiMMP04, complete genome) position: , mismatch: 0, identity: 1.0

ccatagattttaatgtatcaccaacatttttaaaaat	CRISPR spacer
ccatagattttaatgtatcaccaacatttttaaaaat	Protospacer
*************************************

77. spacer 18.23|3276328|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to GU949551 (Clostridium phage phiCD6356, complete genome) position: , mismatch: 0, identity: 1.0

ggagaaggctttgatagtaatacttttgccgtaccact	CRISPR spacer
ggagaaggctttgatagtaatacttttgccgtaccact	Protospacer
**************************************

78. spacer 18.25|3276461|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to GU949551 (Clostridium phage phiCD6356, complete genome) position: , mismatch: 0, identity: 1.0

atttaaagttccgcacaaataatgctaagtcaaagga	CRISPR spacer
atttaaagttccgcacaaataatgctaagtcaaagga	Protospacer
*************************************

79. spacer 18.27|3276592|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to GU949551 (Clostridium phage phiCD6356, complete genome) position: , mismatch: 0, identity: 1.0

cgattttaaatccggatttgaaaggaggggctaacaa	CRISPR spacer
cgattttaaatccggatttgaaaggaggggctaacaa	Protospacer
*************************************

80. spacer 18.29|3276723|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 0, identity: 1.0

ctaagtcaaacattattatatagagcattcttcatta	CRISPR spacer
ctaagtcaaacattattatatagagcattcttcatta	Protospacer
*************************************

81. spacer 18.29|3276723|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 0, identity: 1.0

ctaagtcaaacattattatatagagcattcttcatta	CRISPR spacer
ctaagtcaaacattattatatagagcattcttcatta	Protospacer
*************************************

82. spacer 18.29|3276723|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 0, identity: 1.0

ctaagtcaaacattattatatagagcattcttcatta	CRISPR spacer
ctaagtcaaacattattatatagagcattcttcatta	Protospacer
*************************************

83. spacer 18.29|3276723|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 0, identity: 1.0

ctaagtcaaacattattatatagagcattcttcatta	CRISPR spacer
ctaagtcaaacattattatatagagcattcttcatta	Protospacer
*************************************

84. spacer 18.29|3276723|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 0, identity: 1.0

ctaagtcaaacattattatatagagcattcttcatta	CRISPR spacer
ctaagtcaaacattattatatagagcattcttcatta	Protospacer
*************************************

85. spacer 18.29|3276723|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 0, identity: 1.0

ctaagtcaaacattattatatagagcattcttcatta	CRISPR spacer
ctaagtcaaacattattatatagagcattcttcatta	Protospacer
*************************************

86. spacer 18.29|3276723|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 0, identity: 1.0

ctaagtcaaacattattatatagagcattcttcatta	CRISPR spacer
ctaagtcaaacattattatatagagcattcttcatta	Protospacer
*************************************

87. spacer 18.29|3276723|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 0, identity: 1.0

ctaagtcaaacattattatatagagcattcttcatta	CRISPR spacer
ctaagtcaaacattattatatagagcattcttcatta	Protospacer
*************************************

88. spacer 18.29|3276723|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to KX228400 (Clostridium phage CDKM15, complete genome) position: , mismatch: 0, identity: 1.0

ctaagtcaaacattattatatagagcattcttcatta	CRISPR spacer
ctaagtcaaacattattatatagagcattcttcatta	Protospacer
*************************************

89. spacer 18.31|3276855|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 0, identity: 1.0

tctgttactgtataagttttaccatcaattttagttcc	CRISPR spacer
tctgttactgtataagttttaccatcaattttagttcc	Protospacer
**************************************

90. spacer 18.31|3276855|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

tctgttactgtataagttttaccatcaattttagttcc	CRISPR spacer
tctgttactgtataagttttaccatcaattttagttcc	Protospacer
**************************************

91. spacer 18.31|3276855|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 0, identity: 1.0

tctgttactgtataagttttaccatcaattttagttcc	CRISPR spacer
tctgttactgtataagttttaccatcaattttagttcc	Protospacer
**************************************

92. spacer 18.31|3276855|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

tctgttactgtataagttttaccatcaattttagttcc	CRISPR spacer
tctgttactgtataagttttaccatcaattttagttcc	Protospacer
**************************************

93. spacer 18.31|3276855|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 0, identity: 1.0

tctgttactgtataagttttaccatcaattttagttcc	CRISPR spacer
tctgttactgtataagttttaccatcaattttagttcc	Protospacer
**************************************

94. spacer 18.31|3276855|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to JX145342 (Clostridium phage phiMMP04, complete genome) position: , mismatch: 0, identity: 1.0

tctgttactgtataagttttaccatcaattttagttcc	CRISPR spacer
tctgttactgtataagttttaccatcaattttagttcc	Protospacer
**************************************

95. spacer 18.31|3276855|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_028838 (Clostridium phage phiCD506, complete genome) position: , mismatch: 0, identity: 1.0

tctgttactgtataagttttaccatcaattttagttcc	CRISPR spacer
tctgttactgtataagttttaccatcaattttagttcc	Protospacer
**************************************

96. spacer 18.31|3276855|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 0, identity: 1.0

tctgttactgtataagttttaccatcaattttagttcc	CRISPR spacer
tctgttactgtataagttttaccatcaattttagttcc	Protospacer
**************************************

97. spacer 18.31|3276855|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to LN681538 (Clostridium phage phiCD481-1, complete genome) position: , mismatch: 0, identity: 1.0

tctgttactgtataagttttaccatcaattttagttcc	CRISPR spacer
tctgttactgtataagttttaccatcaattttagttcc	Protospacer
**************************************

98. spacer 18.31|3276855|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 0, identity: 1.0

tctgttactgtataagttttaccatcaattttagttcc	CRISPR spacer
tctgttactgtataagttttaccatcaattttagttcc	Protospacer
**************************************

99. spacer 18.32|3276922|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 0, identity: 1.0

tggtgtggaaaattattttatcttgaagaaaaatcta	CRISPR spacer
tggtgtggaaaattattttatcttgaagaaaaatcta	Protospacer
*************************************

100. spacer 1.1|17753|34|CP012321|CRISPRCasFinder matches to NZ_CP033215 (Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.971

aaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
aaactgaacacatgtgaagtttgtttgttggcgc	Protospacer
*********.************************

101. spacer 2.1|132964|39|CP012321|CRISPRCasFinder matches to NZ_CP033215 (Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.974

agaataaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
agaataaactgaacacatgtgaagtttgtttgttggcgc	Protospacer
**************.************************

102. spacer 3.1|139848|39|CP012321|CRISPRCasFinder matches to NZ_CP033215 (Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.974

agaataaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
agaataaactgaacacatgtgaagtttgtttgttggcgc	Protospacer
**************.************************

103. spacer 5.1|150401|34|CP012321|CRISPRCasFinder matches to NZ_CP033215 (Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.971

aaactgaacgcatgtgaagtttgtttgttggcgc	CRISPR spacer
aaactgaacacatgtgaagtttgtttgttggcgc	Protospacer
*********.************************

104. spacer 7.1|1548851|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 1, identity: 0.973

tattttcatttttgagagttacaaaacatctcaatga-	CRISPR spacer
tattttcatttttgagagttacaaaacatct-aatgat	Protospacer
******************************* *****

105. spacer 7.1|1548851|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 1, identity: 0.973

tattttcatttttgagagttacaaaacatctcaatga-	CRISPR spacer
tattttcatttttgagagttacaaaacatct-aatgat	Protospacer
******************************* *****

106. spacer 7.2|1548917|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 1, identity: 0.974

taaattcgtctaacttaaattaataataggagcttttt	CRISPR spacer
ttaattcgtctaacttaaattaataataggagcttttt	Protospacer
* ************************************

107. spacer 7.2|1548917|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 1, identity: 0.974

taaattcgtctaacttaaattaataataggagcttttt	CRISPR spacer
ttaattcgtctaacttaaattaataataggagcttttt	Protospacer
* ************************************

108. spacer 7.3|1548984|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 1, identity: 0.973

acagttgtattagcaactttaaaagatatacaagact	CRISPR spacer
acagttgtattagcaactttaaaagatatacaagatt	Protospacer
***********************************.*

109. spacer 7.3|1548984|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 1, identity: 0.973

acagttgtattagcaactttaaaagatatacaagact	CRISPR spacer
acagttgtattagcaactttaaaagatatacaagatt	Protospacer
***********************************.*

110. spacer 7.3|1548984|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 1, identity: 0.973

acagttgtattagcaactttaaaagatatacaagact	CRISPR spacer
acagttgtattagcaactttaaaagatatacaagatt	Protospacer
***********************************.*

111. spacer 7.14|1549713|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.973

tatctttagcattatattttttagtatcagatgtgtg	CRISPR spacer
tatctttagcattatattttttagtatcagatgtgtc	Protospacer
************************************

112. spacer 7.14|1549713|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to MF547662 (Clostridioides phage LIBA6276, complete genome) position: , mismatch: 1, identity: 0.973

tatctttagcattatattttttagtatcagatgtgtg	CRISPR spacer
tatctttagcattatattttttagtatcagatgtgtc	Protospacer
************************************

113. spacer 7.14|1549713|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to MF547663 (Clostridioides phage LIBA2945, complete genome) position: , mismatch: 1, identity: 0.973

tatctttagcattatattttttagtatcagatgtgtg	CRISPR spacer
tatctttagcattatattttttagtatcagatgtgtc	Protospacer
************************************

114. spacer 8.5|1660626|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_028838 (Clostridium phage phiCD506, complete genome) position: , mismatch: 1, identity: 0.973

ataagagtggtttaagaaaataagttatttttcaaaa	CRISPR spacer
ataagagtggttaaagaaaataagttatttttcaaaa	Protospacer
************ ************************

115. spacer 8.5|1660626|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 1, identity: 0.973

ataagagtggtttaagaaaataagttatttttcaaaa	CRISPR spacer
ataagagtggttaaagaaaataagttatttttcaaaa	Protospacer
************ ************************

116. spacer 10.9|1835209|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to HM568888 (Clostridium phage phiCD38-2, complete genome) position: , mismatch: 1, identity: 0.974

aataaaaattacactaatgtagacttaattccttccga	CRISPR spacer
aataaaaattacactaatgtagacttaattccttctga	Protospacer
***********************************.**

117. spacer 18.7|3275273|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029156 (Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.974

aagcaaatgagattataaaagctaattcaaacaatctt	CRISPR spacer
aagcaaatgagattataaaagccaattcaaacaatctt	Protospacer
**********************.***************

118. spacer 18.7|3275273|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029153 (Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.974

aagcaaatgagattataaaagctaattcaaacaatctt	CRISPR spacer
aagcaaatgagattataaaagccaattcaaacaatctt	Protospacer
**********************.***************

119. spacer 18.7|3275273|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020425 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.974

aagcaaatgagattataaaagctaattcaaacaatctt	CRISPR spacer
aagcaaatgagattataaaagccaattcaaacaatctt	Protospacer
**********************.***************

120. spacer 18.7|3275273|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to FN668942 (Clostridium difficile BI1 plasmid pCDBI1, complete sequence) position: , mismatch: 1, identity: 0.974

aagcaaatgagattataaaagctaattcaaacaatctt	CRISPR spacer
aagcaaatgagattataaaagccaattcaaacaatctt	Protospacer
**********************.***************

121. spacer 18.7|3275273|38|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP011969 (Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.974

aagcaaatgagattataaaagctaattcaaacaatctt	CRISPR spacer
aagcaaatgagattataaaagccaattcaaacaatctt	Protospacer
**********************.***************

122. spacer 18.20|3276131|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to KU057941 (Clostridium phage CDSH1, complete genome) position: , mismatch: 1, identity: 0.973

gaaagaactgttatgtataaaaataactaaaaaatgg	CRISPR spacer
gaaagaactgttatgtataaaaacaactaaaaaatgg	Protospacer
***********************.*************

123. spacer 18.20|3276131|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_028905 (Clostridium phage phiCD111, complete genome) position: , mismatch: 1, identity: 0.973

gaaagaactgttatgtataaaaataactaaaaaatgg	CRISPR spacer
gaaagaactgttatgtataaaaacaactaaaaaatgg	Protospacer
***********************.*************

124. spacer 18.20|3276131|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to HM568888 (Clostridium phage phiCD38-2, complete genome) position: , mismatch: 1, identity: 0.973

gaaagaactgttatgtataaaaataactaaaaaatgg	CRISPR spacer
gaaagaactgttatgtataaaaacaactaaaaaatgg	Protospacer
***********************.*************

125. spacer 18.20|3276131|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_028958 (Clostridium phage phiCD146, complete genome) position: , mismatch: 1, identity: 0.973

gaaagaactgttatgtataaaaataactaaaaaatgg	CRISPR spacer
gaaagaactgttatgtataaaaacaactaaaaaatgg	Protospacer
***********************.*************

126. spacer 18.20|3276131|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to LN881738 (Escherichia phage slur17, complete genome) position: , mismatch: 1, identity: 0.973

gaaagaactgttatgtataaaaataactaaaaaatgg	CRISPR spacer
gaaagaactgttatgtataaaaacaactaaaaaatgg	Protospacer
***********************.*************

127. spacer 18.28|3276658|36|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029156 (Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.972

ttctagtaataaatatgaaaaatttacatttaatgg	CRISPR spacer
ttctagtaataaatatgaagaatttacatttaatgg	Protospacer
*******************.****************

128. spacer 18.28|3276658|36|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029153 (Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.972

ttctagtaataaatatgaaaaatttacatttaatgg	CRISPR spacer
ttctagtaataaatatgaagaatttacatttaatgg	Protospacer
*******************.****************

129. spacer 7.14|1549713|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.946

tatctttagcattatattttttagtatcagatgtgtg	CRISPR spacer
tatctttagcattatattttttagtgtcagatgtgtc	Protospacer
*************************.**********

130. spacer 7.14|1549713|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 2, identity: 0.946

tatctttagcattatattttttagtatcagatgtgtg	CRISPR spacer
tatctttagcattatattttttagtgtcagatgtgtc	Protospacer
*************************.**********

131. spacer 7.14|1549713|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 2, identity: 0.946

tatctttagcattatattttttagtatcagatgtgtg	CRISPR spacer
tatctttagcattatattttttagtgtcagatgtgtc	Protospacer
*************************.**********

132. spacer 7.16|1549846|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_028958 (Clostridium phage phiCD146, complete genome) position: , mismatch: 2, identity: 0.947

tctatccaccccc-ttttttataaatttgcattaaaaaa	CRISPR spacer
-ctatccaccccctttttttatgaatttgcattaaaaaa	Protospacer
 ************ ********.****************

133. spacer 8.3|1660495|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029156 (Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.946

agagcagatgtctggtgttttggattcccatgtcaag	CRISPR spacer
aaagcagatgtgtggtgttttggattcccatgtcaag	Protospacer
*.********* *************************

134. spacer 8.3|1660495|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029153 (Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.946

agagcagatgtctggtgttttggattcccatgtcaag	CRISPR spacer
aaagcagatgtgtggtgttttggattcccatgtcaag	Protospacer
*.********* *************************

135. spacer 8.5|1660626|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 2, identity: 0.946

ataagagtggtttaagaaaataagttatttttcaaaa	CRISPR spacer
ctaagagtggtttaagaaaataagttatttttcaaag	Protospacer
 ***********************************.

136. spacer 8.5|1660626|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 2, identity: 0.946

ataagagtggtttaagaaaataagttatttttcaaaa	CRISPR spacer
ctaagagtggtttaagaaaataagttatttttcaaag	Protospacer
 ***********************************.

137. spacer 8.5|1660626|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN681538 (Clostridium phage phiCD481-1, complete genome) position: , mismatch: 2, identity: 0.946

ataagagtggtttaagaaaataagttatttttcaaaa	CRISPR spacer
ctaagagtggtttaagaaaataagttatttttcaaag	Protospacer
 ***********************************.

138. spacer 8.5|1660626|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 2, identity: 0.946

ataagagtggtttaagaaaataagttatttttcaaaa	CRISPR spacer
ctaagagtggtttaagaaaataagttatttttcaaag	Protospacer
 ***********************************.

139. spacer 8.9|1660893|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MG973074 (Clostridioides difficile strain HSJD-312 plasmid pHSJD-312, complete sequence) position: , mismatch: 2, identity: 0.946

agcaattctgatatttttattctaatcatttgaaatc	CRISPR spacer
agcaattctgatatttttattctgatcatttaaaatc	Protospacer
***********************.*******.*****

140. spacer 9.1|1722566|37|CP012321|CRISPRCasFinder matches to KX905163 (Clostridioides phage phiSemix9P1, complete genome) position: , mismatch: 2, identity: 0.946

ctttaaaatagttgaaagaaatgaagcaattaaagta	CRISPR spacer
ctttaaagtagttgaaagaaatgaagcaatcaaagta	Protospacer
*******.**********************.******

141. spacer 10.3|1834817|36|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 2, identity: 0.944

ccactattactttctatgtcagctttgttaacttcg	CRISPR spacer
ccactattactttctatatcagctttgttaacttca	Protospacer
*****************.*****************.

142. spacer 10.3|1834817|36|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 2, identity: 0.944

ccactattactttctatgtcagctttgttaacttcg	CRISPR spacer
ccactattactttctatatcagctttgttaacttca	Protospacer
*****************.*****************.

143. spacer 11.1|2528661|36|CP012321|CRISPRCasFinder,CRT matches to NZ_MG973074 (Clostridioides difficile strain HSJD-312 plasmid pHSJD-312, complete sequence) position: , mismatch: 2, identity: 0.944

acaattattaattgttttattagtgaaatcacagca	CRISPR spacer
acaattattaattgttttattaataaaatcacagca	Protospacer
**********************.*.***********

144. spacer 11.12|2529384|36|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 2, identity: 0.944

gagatattactagattgaaaaaactgaaaaaagata	CRISPR spacer
gagatattgctagattaaaaaaactgaaaaaagata	Protospacer
********.*******.*******************

145. spacer 11.12|2529384|36|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 2, identity: 0.944

gagatattactagattgaaaaaactgaaaaaagata	CRISPR spacer
gagatattgctagattaaaaaaactgaaaaaagata	Protospacer
********.*******.*******************

146. spacer 13.7|2775751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 2, identity: 0.946

aagtcaaaaggttaaatttaaataaaattatacttct	CRISPR spacer
aagccaaaaggttaaatttaaataaaattaaacttct	Protospacer
***.************************** ******

147. spacer 18.12|3275605|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 2, identity: 0.946

cagttcctcacctcttaatacaccagaacccaaccct	CRISPR spacer
cagttcctcacctcttaatacgccagaactcaaccct	Protospacer
*********************.*******.*******

148. spacer 18.12|3275605|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 2, identity: 0.946

cagttcctcacctcttaatacaccagaacccaaccct	CRISPR spacer
cagttcctcacctcttaatacgccagaactcaaccct	Protospacer
*********************.*******.*******

149. spacer 18.12|3275605|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 2, identity: 0.946

cagttcctcacctcttaatacaccagaacccaaccct	CRISPR spacer
cagttcctcacctcttaatacgccagaactcaaccct	Protospacer
*********************.*******.*******

150. spacer 18.32|3276922|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 2, identity: 0.946

tggtgtggaaaattattttatcttgaagaaaaatcta	CRISPR spacer
tggtgtggtaagttattttatcttgaagaaaaatcta	Protospacer
******** **.*************************

151. spacer 18.32|3276922|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 2, identity: 0.946

tggtgtggaaaattattttatcttgaagaaaaatcta	CRISPR spacer
tggtgtggtaagttattttatcttgaagaaaaatcta	Protospacer
******** **.*************************

152. spacer 18.32|3276922|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 2, identity: 0.946

tggtgtggaaaattattttatcttgaagaaaaatcta	CRISPR spacer
tggtgtggtaagttattttatcttgaagaaaaatcta	Protospacer
******** **.*************************

153. spacer 7.3|1548984|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029156 (Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.919

acagttgtattagcaactttaaaagatatacaagact	CRISPR spacer
acagttgtattagcaactttaaaagacatacaggacc	Protospacer
**************************.*****.***.

154. spacer 7.3|1548984|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029153 (Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.919

acagttgtattagcaactttaaaagatatacaagact	CRISPR spacer
acagttgtattagcaactttaaaagacatacaggacc	Protospacer
**************************.*****.***.

155. spacer 7.16|1549846|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN881738 (Escherichia phage slur17, complete genome) position: , mismatch: 3, identity: 0.921

-tctatccacccccttttttataaatttgcattaaaaaa	CRISPR spacer
atttattcaccccc-tttttataaatttgcattaaaaaa	Protospacer
 *.***.******* ************************

156. spacer 7.16|1549846|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to KU057941 (Clostridium phage CDSH1, complete genome) position: , mismatch: 3, identity: 0.921

-tctatccacccccttttttataaatttgcattaaaaaa	CRISPR spacer
atttattcaccccc-tttttataaatttgcattaaaaaa	Protospacer
 *.***.******* ************************

157. spacer 7.16|1549846|38|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_028905 (Clostridium phage phiCD111, complete genome) position: , mismatch: 3, identity: 0.921

-tctatccacccccttttttataaatttgcattaaaaaa	CRISPR spacer
atctattcaccccc-tttttataaatttgcattaaaaag	Protospacer
 *****.******* ***********************.

158. spacer 8.10|1660959|38|CP012321|CRISPRCasFinder,CRT matches to NZ_MG973074 (Clostridioides difficile strain HSJD-312 plasmid pHSJD-312, complete sequence) position: , mismatch: 3, identity: 0.921

ccatcttttgttgctttacataaatttatattacttat	CRISPR spacer
ccatcttttgttgctttgcatagatttatattacttac	Protospacer
*****************.****.**************.

159. spacer 10.4|1834882|34|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 3, identity: 0.912

aaattcacagagctttggtgggaatatacaaaac	CRISPR spacer
aaattcacagagctttggtggaaatatgcaaaat	Protospacer
*********************.*****.*****.

160. spacer 10.10|1835276|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to GU949551 (Clostridium phage phiCD6356, complete genome) position: , mismatch: 3, identity: 0.919

tttttaaagtaatggttactttttaaaatagaaaagt	CRISPR spacer
tttgtcaagtaatggttactttttaaaatagaaaagc	Protospacer
*** * ******************************.

161. spacer 18.29|3276723|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 3, identity: 0.919

ctaagtcaaacattattatatagagcattcttcatta	CRISPR spacer
ctgagtcaaacattattatatagagcattcttcgttg	Protospacer
**.******************************.**.

162. spacer 18.29|3276723|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 3, identity: 0.919

ctaagtcaaacattattatatagagcattcttcatta	CRISPR spacer
ctgagtcaaacattattatatagagcattcttcgttg	Protospacer
**.******************************.**.

163. spacer 18.29|3276723|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 3, identity: 0.919

ctaagtcaaacattattatatagagcattcttcatta	CRISPR spacer
ctgagtcaaacattattatatagagcattcttcgttg	Protospacer
**.******************************.**.

164. spacer 19.5|3604249|25|CP012321|CRT matches to MG592614 (Vibrio phage 1.248.O._10N.261.54.F1, partial genome) position: , mismatch: 3, identity: 0.88

tcctgttattccatttgctccagtc	CRISPR spacer
tgatgatattccatttgctccagtc	Protospacer
*  ** *******************

165. spacer 19.5|3604249|25|CP012321|CRT matches to MN693124 (Marine virus AFVG_25M44, complete genome) position: , mismatch: 3, identity: 0.88

tcctgttattccatttgctccagtc	CRISPR spacer
tcctgttattccatttactccattt	Protospacer
****************.***** *.

166. spacer 19.7|3604348|25|CP012321|CRT matches to MN693124 (Marine virus AFVG_25M44, complete genome) position: , mismatch: 3, identity: 0.88

tcctgttattccatttgctccggtt	CRISPR spacer
tcctgttattccatttactccattt	Protospacer
****************.****. **

167. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to KC821618 (Cellulophaga phage phi10:1, complete genome) position: , mismatch: 4, identity: 0.867

ctaagtt-ttaaaaaaattaatataaacaac	CRISPR spacer
-taatttatttaaaaaactaatataaacaac	Protospacer
 *** ** ** ******.*************

168. spacer 7.1|1548851|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 4, identity: 0.892

tattttcatttttgagagttacaaaacatctcaatga	CRISPR spacer
tattttcatttttgagagttacaaaacacttcaaaaa	Protospacer
****************************..**** .*

169. spacer 7.1|1548851|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 4, identity: 0.892

tattttcatttttgagagttacaaaacatctcaatga	CRISPR spacer
tattttcatttttgagagttacaaaacacttcaaaaa	Protospacer
****************************..**** .*

170. spacer 7.1|1548851|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to KX228400 (Clostridium phage CDKM15, complete genome) position: , mismatch: 4, identity: 0.892

tattttcatttttgagagttacaaaacatctcaatga	CRISPR spacer
tattttcatttttgagagttacaaaacacttcaaaaa	Protospacer
****************************..**** .*

171. spacer 7.1|1548851|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 4, identity: 0.892

tattttcatttttgagagttacaaaacatctcaatga	CRISPR spacer
tattttcatttttgagagttacaaaacacttcaaaaa	Protospacer
****************************..**** .*

172. spacer 7.1|1548851|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 4, identity: 0.892

tattttcatttttgagagttacaaaacatctcaatga	CRISPR spacer
tattttcatttttgagagttacaaaacacttcaaaaa	Protospacer
****************************..**** .*

173. spacer 7.1|1548851|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 4, identity: 0.892

tattttcatttttgagagttacaaaacatctcaatga	CRISPR spacer
tattttcatttttgagagttacaaaacacttcaacaa	Protospacer
****************************..****..*

174. spacer 7.1|1548851|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 4, identity: 0.892

tattttcatttttgagagttacaaaacatctcaatga	CRISPR spacer
tattttcatttttgagagttacaaaacacttcaaaaa	Protospacer
****************************..**** .*

175. spacer 8.5|1660626|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_028905 (Clostridium phage phiCD111, complete genome) position: , mismatch: 4, identity: 0.892

ataagagtggtttaagaaaataagttatttttcaaaa	CRISPR spacer
ataagagtggtttaagaaaataagttatttttaatct	Protospacer
******************************** *

176. spacer 19.5|3604249|25|CP012321|CRT matches to MG592608 (Vibrio phage 1.243.O._10N.261.54.B5, partial genome) position: , mismatch: 4, identity: 0.84

tcctgttattccatttgctccagtc	CRISPR spacer
tgacgatattccatttgctccagtc	Protospacer
*  .* *******************

177. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP045692 (Klebsiella pneumoniae strain TK421 plasmid pTK421_2, complete sequence) position: , mismatch: 5, identity: 0.833

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
tttagttttaaaaaaagtaataaaaacaaa	Protospacer
.* ************* ***** ******

178. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP042421 (Leuconostoc lactis strain CBA3622 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.833

ctaagt--tttaaaaaaattaatataaacaac	CRISPR spacer
--aactcgtttaaaaaaattaatataaataaa	Protospacer
  ** *  ********************.**

179. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 5, identity: 0.833

ctaagttttaaaaaaattaa-tataaacaac	CRISPR spacer
ctaagttctaaaaaaattaattatgatcga-	Protospacer
*******.************ ***.* *.*

180. spacer 4.1|148386|29|CP012321|CRISPRCasFinder matches to KY971610 (Pseudomonas phage PspYZU05, complete genome) position: , mismatch: 6, identity: 0.793

tgtaataagttaaagcaatatgaatcaac	CRISPR spacer
tacgataagttacagcaatacgaatcatc	Protospacer
*...******** *******.****** *

181. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP009068 (Borreliella afzelii K78 plasmid cp32-9, complete sequence) position: , mismatch: 6, identity: 0.8

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
gacacttttaagaaaaataatataaacaac	Protospacer
   * ******.**** *************

182. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP009069 (Borreliella afzelii K78 plasmid cp32-4, complete sequence) position: , mismatch: 6, identity: 0.8

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
gacacttttaagaaaaataatataaacaac	Protospacer
   * ******.**** *************

183. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NC_015917 (Borreliella bissettii DN127 plasmid lp28-4, complete sequence) position: , mismatch: 6, identity: 0.8

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
taatgatttaaaaaatttaatagaaacaac	Protospacer
. * * ********* ****** *******

184. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 6, identity: 0.8

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
gtgcgctttaaaagaattaatgtaaacaac	Protospacer
 *. *.*******.*******.********

185. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
caaacttttaaaaaaattaatttaaaaatt	Protospacer
* ** **************** **** * .

186. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP030264 (Ensifer adhaerens strain Corn53 plasmid AB, complete sequence) position: , mismatch: 6, identity: 0.8

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
gtgcgctttaaaagaattaatgtaaacaac	Protospacer
 *. *.*******.*******.********

187. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP042215 (Enterococcus faecalis strain L15 plasmid pL15-A, complete sequence) position: , mismatch: 6, identity: 0.8

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
caaacttttaaaaaaattaatttaaaaatt	Protospacer
* ** **************** **** * .

188. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to CP040041 (Acinetobacter baumannii strain VB958 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

---ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
accgtaa---ttaaaaaaattaataggaacaac	Protospacer
    ***   *************** .******

189. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to CP016195 (Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-1, complete sequence) position: , mismatch: 7, identity: 0.767

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
taaaattttaaaaaaattaatataataata	Protospacer
. **.********************  *

190. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to MN693725 (Marine virus AFVG_250M494, complete genome) position: , mismatch: 7, identity: 0.767

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
tttttttttaaaaaaattaaaacaaacaaa	Protospacer
.*   *************** *.******

191. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP017230 (Campylobacter jejuni strain FORC_046 isolate Not reported plasmid pFORC46.1, complete sequence) position: , mismatch: 7, identity: 0.767

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
ttagattttaaaaaaattaatatgaaaatt	Protospacer
.**..******************.** * .

192. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NC_017577 (Shewanella baltica OS117 plasmid pSBAL11701, complete sequence) position: , mismatch: 7, identity: 0.767

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
gaaaagtttaaaaaaataaataaaaacaaa	Protospacer
  **. *********** **** ******

193. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 7, identity: 0.767

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aaaagtttttaaaaaattcatataataaat	Protospacer
  ******* ******** ******  **.

194. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP014203 (Clostridium baratii strain CDC51267 plasmid pNPD11_1, complete sequence) position: , mismatch: 7, identity: 0.767

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
ctttaattttaaataattaatataaacaaa	Protospacer
**  . *** *** ***************

195. spacer 7.7|1549249|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to MN694790 (Marine virus AFVG_250M551, complete genome) position: , mismatch: 7, identity: 0.811

ccacttgttcttcaattattttatctacgcagcctaa---	CRISPR spacer
tcacttgttcttcaattaatttattta---atcctaaaac	Protospacer
.***************** *****.**   * *****

196. spacer 13.7|2775751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 7, identity: 0.811

aagtcaaaaggttaaatttaaataaaattatacttct	CRISPR spacer
aagtcaaaaagttaaattcaaataaaattaaattaaa	Protospacer
*********.********.*********** *.*

197. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP006906 (Clostridium baratii str. Sullivan plasmid pCBJ, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
tactattttaaccaaattaatataaacaat	Protospacer
.   .******  ****************.

198. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to MN693547 (Marine virus AFVG_25M424, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aaaagtttaaaaaaaaataatataaatttt	Protospacer
  ****** ******* *********.  .

199. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to MN693297 (Marine virus AFVG_25M423, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aaaagtttaaaaaaaaataatataaatttt	Protospacer
  ****** ******* *********.  .

200. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP006570 (Sodalis praecaptivus strain HS1 plasmid pHS1, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
gattgttttaaaaaaaataatataaaatat	Protospacer
    ************ *********  *.

201. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to AP014396 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S46-C203, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aaaagtttaaaaaaaaataatataaattta	Protospacer
  ****** ******* *********.

202. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to MN693353 (Marine virus AFVG_25M425, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aaaagtttaaaaaaaaataatataaatttt	Protospacer
  ****** ******* *********.  .

203. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP028373 (Campylobacter jejuni subsp. jejuni strain huA17 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
cggttttttaaaaaaactaatataaatata	Protospacer
* .  ***********.*********.*

204. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP028373 (Campylobacter jejuni subsp. jejuni strain huA17 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
cggttttttaaaaaaactaatataaatata	Protospacer
* .  ***********.*********.*

205. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to AP022644 (Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
tcacattttaaaaaaattaataaaaaaaca	Protospacer
..* .***************** *** *

206. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_LR214999 (Mycoplasma conjunctivae strain NCTC10147 plasmid 3) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
atttattttaaaaaaattaatacaaaaatt	Protospacer
 *  .*****************.*** * .

207. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to LR214965 (Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 11) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
atttattttaaaaaaattaatacaaaaatt	Protospacer
 *  .*****************.*** * .

208. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP014745 (Campylobacter jejuni strain OD267 plasmid pCJDM67 L, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
cggttttttaaaaaaactaatataaatata	Protospacer
* .  ***********.*********.*

209. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to CP024686 (Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-2-313K, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
tcacattttaaaaaaattaataaaaaaaca	Protospacer
..* .***************** *** *

210. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP014345 (Campylobacter jejuni strain RM3194 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
cggttttttaaaaaaactaatataaatata	Protospacer
* .  ***********.*********.*

211. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP014345 (Campylobacter jejuni strain RM3194 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
cggttttttaaaaaaactaatataaatata	Protospacer
* .  ***********.*********.*

212. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP014743 (Campylobacter jejuni strain WP2202 plasmid pCJDM202, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
cggttttttaaaaaaactaatataaatata	Protospacer
* .  ***********.*********.*

213. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP017417 (Campylobacter jejuni strain MTVDSCj13 plasmid pMTVDSCj13-2, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
cggttttttaaaaaaactaatataaatata	Protospacer
* .  ***********.*********.*

214. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_LR134420 (Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 11) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
ctaacttttaaaaaaattagtatcgccgcg	Protospacer
**** **************.*** . *.

215. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP044174 (Campylobacter jejuni strain AR-0412 plasmid pAR-0412, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
cggttttttaaaaaaactaatataaaatat	Protospacer
* .  ***********.*********  *.

216. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to MK448965 (Streptococcus phage Javan506, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
cacttgttcaaaaaaattaatataatcaat	Protospacer
*     **.**************** ***.

217. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NC_007581 (Clostridium phage c-st, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aagaataagaaaaaaattaatataaccaac	Protospacer
  .*.*   **************** ****

218. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
cacttgttcaaaaaaattaatataatcaat	Protospacer
*     **.**************** ***.

219. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to MK448686 (Streptococcus phage Javan157, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
cactcgttcaaaaaaattaatataatcaat	Protospacer
*     **.**************** ***.

220. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to MK448949 (Streptococcus phage Javan460, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
cacttgttcaaaaaaattaatataatcaat	Protospacer
*     **.**************** ***.

221. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to MK448951 (Streptococcus phage Javan470, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
cactcgttcaaaaaaattaatataatcaat	Protospacer
*     **.**************** ***.

222. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to MK448676 (Streptococcus phage Javan131, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
cactcgttcaaaaaaattaatataatcaat	Protospacer
*     **.**************** ***.

223. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to AP008983 (Clostridium phage c-st genomic DNA, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aagaataagaaaaaaattaatataaccaac	Protospacer
  .*.*   **************** ****

224. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP043762 (Paenibacillus sp. 37 plasmid pART37, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
tcgggattcaaaaaaattaatataaccaag	Protospacer
....* **.**************** ***

225. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP019232 (Bacillus thuringiensis strain YGd22-03 plasmid pYGD36, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
gaaagttttaaaaaaatcattataataata	Protospacer
  ***************.* *****  *

226. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP010112 (Bacillus thuringiensis serovar indiana strain HD521 plasmid pBTHD521-6, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
tcacattttaaaaaaattaataaaaaaaca	Protospacer
..* .***************** *** *

227. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
tcacattttaaaaaaattaataaaaaaaca	Protospacer
..* .***************** *** *

228. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to CP012553 (Campylobacter sp. RM16192 plasmid p16192, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
tttgattttaaaaaaattaatgtaaaaatt	Protospacer
.* ..****************.**** * .

229. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to KY554775 (Lactococcus phage AM11, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aggaaatttaaaaacattaatataaataaa	Protospacer
  .*. ******** ***********.**

230. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to KY554773 (Lactococcus phage AM8, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aggaaatttaaaaacattaatataaataaa	Protospacer
  .*. ******** ***********.**

231. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to KY554768 (Lactococcus phage AM1, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aggaaatttaaaaacattaatataaataaa	Protospacer
  .*. ******** ***********.**

232. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to KY554769 (Lactococcus phage AM2, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aggaaatttaaaaacattaatataaataaa	Protospacer
  .*. ******** ***********.**

233. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to KY554770 (Lactococcus phage AM3, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aggaaatttaaaaacattaatataaataaa	Protospacer
  .*. ******** ***********.**

234. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to MN694408 (Marine virus AFVG_250M293, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aatagtttaaaaaaaattaatagaaaatgc	Protospacer
   ***** ************* ***  .*

235. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to KY554776 (Lactococcus phage AM12, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aggaaatttaaaaacattaatataaataaa	Protospacer
  .*. ******** ***********.**

236. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to KY554774 (Lactococcus phage AM9, complete genome) position: , mismatch: 8, identity: 0.733

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aggaaatttaaaaacattaatataaataaa	Protospacer
  .*. ******** ***********.**

237. spacer 7.3|1548984|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 8, identity: 0.784

acagttgtattagcaactttaaaagatatacaagact	CRISPR spacer
actgtcattctagcaactttaaaagatatgcaggacc	Protospacer
** **..* .*******************.**.***.

238. spacer 7.3|1548984|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 8, identity: 0.784

acagttgtattagcaactttaaaagatatacaagact	CRISPR spacer
actgtcattctagcaactttaaaagatatgcaggacc	Protospacer
** **..* .*******************.**.***.

239. spacer 11.3|2528793|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to CP000313 (Clostridium perfringens SM101 plasmid pSM101A, complete sequence) position: , mismatch: 8, identity: 0.784

aagtataagct--ttagaagtggagtgcctgtcctagtg	CRISPR spacer
--ataatagtttcttagtagtggagtgcctgtcctggtg	Protospacer
  .**  **.*  **** *****************.***

240. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP004877 (Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMB431, complete sequence) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
taatattttaaaaaaattcatataaaattt	Protospacer
. * .************* *******   .

241. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP004860 (Bacillus thuringiensis serovar kurstaki str. YBT-1520 plasmid pBMB422, complete sequence) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
taatattttaaaaaaattcatataaaattt	Protospacer
. * .************* *******   .

242. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP011156 (Bacillus cereus strain HN001 plasmid pRML01, complete sequence) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
atttattttaaaaatattaatataaatgga	Protospacer
 *  .********* ***********...

243. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP010090 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB426, complete sequence) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
taatattttaaaaaaattcatataaaattt	Protospacer
. * .************* *******   .

244. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to AP013426 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C57-MedDCM-OCT-S27-C24) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
tcttttgttaaaaaaattaatatgaacaga	Protospacer
..   * ****************.****.

245. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to KJ535721 (Listeria phage List-36, complete genome) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
gatagtaataaaaaaattaatataaagtgt	Protospacer
   ***  ******************  ..

246. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP014283 (Bacillus thuringiensis strain Bt185 plasmid pBT1850636, complete sequence) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
atttattttaaaaatattaatataaatgga	Protospacer
 *  .********* ***********...

247. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP033461 (Brevibacillus laterosporus strain 1821L plasmid p1821L01, complete sequence) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
taaagttttaaaaacattaatagaaggtct	Protospacer
. ************ ******* **.   .

248. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP011350 (Bacillus thuringiensis strain YC-10 plasmid pYC1, complete sequence) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
taatattttaaaaaaattcatataaaattt	Protospacer
. * .************* *******   .

249. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP032614 (Bacillus thuringiensis strain QZL38 plasmid p.1, complete sequence) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
atttattttaaaaatattaatataaatgga	Protospacer
 *  .********* ***********...

250. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP007616 (Bacillus thuringiensis serovar kurstaki str. YBT-1520 plasmid pBMB400, complete sequence) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
taatattttaaaaaaattcatataaaattt	Protospacer
. * .************* *******   .

251. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NC_002253 (Buchnera aphidicola str. APS (Acyrthosiphon pisum) plasmid pLeu, complete sequence) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
tttttttttaaaaaaactaatataaaagta	Protospacer
.*   ***********.********* .

252. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP023246 (Bacillus cereus strain HBL-AI plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
taatattttaaaaaaattcatataaaattt	Protospacer
. * .************* *******   .

253. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP048772 (Campylobacter jejuni strain ZS007 plasmid pCJ145K, complete sequence) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
ggtttttttaaaaaaactaatataaatata	Protospacer
     ***********.*********.*

254. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP048772 (Campylobacter jejuni strain ZS007 plasmid pCJ145K, complete sequence) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
ggtttttttaaaaaaactaatataaatata	Protospacer
     ***********.*********.*

255. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to MN172529 (Listeria phage LP-039, complete genome) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
gatagtaataaaaaaattaatataaagtgt	Protospacer
   ***  ******************  ..

256. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to DQ003638 (Listeria phage A511, complete genome) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
gatagtaataaaaaaattaatataaagtgt	Protospacer
   ***  ******************  ..

257. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to KJ591604 (Listeria phage LMTA-148, complete genome) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
gatagtaataaaaaaattaatataaagtgt	Protospacer
   ***  ******************  ..

258. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to KJ094033 (Listeria phage LP-048, complete genome) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
gatagtaataaaaaaattaatataaagtgt	Protospacer
   ***  ******************  ..

259. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to JQ797329 (Listeria phage vB_LmoM_AG20, complete genome) position: , mismatch: 9, identity: 0.7

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
gatagtaataaaaaaattaatataaagtgt	Protospacer
   ***  ******************  ..

260. spacer 7.7|1549249|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to GU949551 (Clostridium phage phiCD6356, complete genome) position: , mismatch: 9, identity: 0.757

ccacttgttcttcaattattttatctacgcagcctaa	CRISPR spacer
ttttagattgttcaattaatttatctacgcagcctaa	Protospacer
.. .  .** ******** ******************

261. spacer 9.1|1722566|37|CP012321|CRISPRCasFinder matches to NZ_CP011156 (Bacillus cereus strain HN001 plasmid pRML01, complete sequence) position: , mismatch: 9, identity: 0.757

ctttaaaatagttgaaagaaatgaagcaattaaagta	CRISPR spacer
tgtaaatgaaattgaaagaattgaagcaaataaagta	Protospacer
. * ** . *.********* ******** *******

262. spacer 18.28|3276658|36|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013044 (Clostridium perfringens strain JP55 plasmid pJFP55J, complete sequence) position: , mismatch: 9, identity: 0.75

ttctagtaataaatatgaaaaatttacatttaatgg	CRISPR spacer
aggaggtaatatatatgaaaaatttaaatttaaatg	Protospacer
    .****** ************** ******  *

263. spacer 18.28|3276658|36|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MK275624 (Clostridium perfringens strain JXJA17 plasmid p6, complete sequence) position: , mismatch: 9, identity: 0.75

ttctagtaataaatatgaaaaatttacatttaatgg	CRISPR spacer
aggaggtaatatatatgaaaaatttaaatttaaatg	Protospacer
    .****** ************** ******  *

264. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to KJ018210 (Flavobacterium sp. phage 1/32, complete genome) position: , mismatch: 10, identity: 0.667

ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
tagtaaattacaaaaattaatataaacatt	Protospacer
. . .  *** ***************** .

265. spacer 7.12|1549579|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to MN855790 (Bacteriophage sp. isolate 76, complete genome) position: , mismatch: 10, identity: 0.73

tagattttttcacaaataaacttaacgagtacaatga	CRISPR spacer
ttaacaccaccacaaataaacttaatgtgtacaatga	Protospacer
* .*. .. .***************.* *********

266. spacer 11.1|2528661|36|CP012321|CRISPRCasFinder,CRT matches to NZ_CP045274 (Bacillus megaterium strain FDU301 plasmid pFDU301B, complete sequence) position: , mismatch: 10, identity: 0.722

acaattattaattgttttattagtgaaatcacagca	CRISPR spacer
tgaattcttaattgttttattagagaaatacctttt	Protospacer
  **** **************** *****  *  .

267. spacer 13.7|2775751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to GU949551 (Clostridium phage phiCD6356, complete genome) position: , mismatch: 10, identity: 0.73

aagtcaaaaggttaaatttaaataaaattatacttct	CRISPR spacer
aagtcaaagtgttaaatttaaataaaatataaaaaag	Protospacer
********. ******************   *

268. spacer 13.7|2775751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019601 (Brachyspira hyodysenteriae strain BH718 plasmid pBH718, complete sequence) position: , mismatch: 10, identity: 0.73

aagtca--aaaggttaaatttaaataaaattatacttct	CRISPR spacer
--tttaataaatgttaaatttaaataaatttataataaa	Protospacer
   *.*  *** **************** ***** *

269. spacer 13.7|2775751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NC_012226 (Brachyspira hyodysenteriae WA1 plasmid pBHWA1, complete sequence) position: , mismatch: 10, identity: 0.73

aagtca--aaaggttaaatttaaataaaattatacttct	CRISPR spacer
--tttaataaatgttaaatttaaataaatttataataaa	Protospacer
   *.*  *** **************** ***** *

270. spacer 13.7|2775751|37|CP012321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016085 (Brachyspira hyodysenteriae ATCC 27164 strain B-78 plasmid pBhyoB78, complete sequence) position: , mismatch: 10, identity: 0.73

aagtca--aaaggttaaatttaaataaaattatacttct	CRISPR spacer
--tttaataaatgttaaatttaaataaatttataataaa	Protospacer
   *.*  *** **************** ***** *

271. spacer 14.1|3007474|34|CP012321|CRISPRCasFinder matches to MN856057 (Bacteriophage sp. isolate 161, complete genome) position: , mismatch: 10, identity: 0.706

tagcatctttccatatttgtctaaatagtaagac	CRISPR spacer
agacttcttaccatatttgtctacatagtcattt	Protospacer
 ..* **** ************* ***** *  .

272. spacer 14.1|3007474|34|CP012321|CRISPRCasFinder matches to MN855979 (Bacteriophage sp. isolate 144, complete genome) position: , mismatch: 10, identity: 0.706

tagcatctttccatatttgtctaaatagtaagac	CRISPR spacer
agacttcttaccatatttgtctacatagtcattt	Protospacer
 ..* **** ************* ***** *  .

273. spacer 18.28|3276658|36|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 10, identity: 0.722

ttctagtaataaatatgaaaaatttacatttaatgg	CRISPR spacer
atcatttaataaatatgaaacaattacatttacaat	Protospacer
 **   ************** * *********  .

274. spacer 19.9|3604438|34|CP012321|CRT matches to KT151959 (Brevibacillus phage Sundance, complete genome) position: , mismatch: 10, identity: 0.706

tcctgtagaacctgttgttccatttggtccagtt	CRISPR spacer
ctttgtagaacctgttgtaccaattggcttagag	Protospacer
...*************** *** ****...**

275. spacer 14.1|3007474|34|CP012321|CRISPRCasFinder matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 11, identity: 0.676

tagcatctttccatatttgtctaaatagtaagac	CRISPR spacer
cctcatatttccatatttgtcaaaatatggaaga	Protospacer
.  *** ************** *****  .*..

276. spacer 18.32|3276922|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to CP016281 (Clostridium tyrobutyricum strain W428 plasmid pW428, complete sequence) position: , mismatch: 13, identity: 0.649

tggtgtggaaaattattttatcttgaagaaaaatcta	CRISPR spacer
gataaaggaaaattattttattatgaagaaaataaag	Protospacer
 .  . ***************. *********    .

277. spacer 18.32|3276922|37|CP012321|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014171 (Clostridium tyrobutyricum strain KCTC 5387 plasmid pCTK01, complete sequence) position: , mismatch: 13, identity: 0.649

tggtgtggaaaattattttatcttgaagaaaaatcta	CRISPR spacer
gataaaggaaaattattttattatgaagaaaataaag	Protospacer
 .  . ***************. *********    .

278. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP011156 (Bacillus cereus strain HN001 plasmid pRML01, complete sequence) position: , mismatch: 16, identity: 0.467

----------ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aatatatatataaatttttttaaaaattat----------	Protospacer
          . ** ****  ********

279. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP040783 (Bacillus thuringiensis strain HM-311 plasmid p1, complete sequence) position: , mismatch: 16, identity: 0.467

----------ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aatatatatataaatttttttaaaaattat----------	Protospacer
          . ** ****  ********

280. spacer 6.1|1076578|30|CP012321|CRISPRCasFinder matches to NZ_CP014283 (Bacillus thuringiensis strain Bt185 plasmid pBT1850636, complete sequence) position: , mismatch: 16, identity: 0.467

----------ctaagttttaaaaaaattaatataaacaac	CRISPR spacer
aatatatatataaatttttttaaaaattat----------	Protospacer
          . ** ****  ********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

248336 : 327574

Streptococcus_phage(33.33%)

protease,transposase,coat,holin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXU59399.1\|248336_248927_+\|protease	membrane-associated metalloprotease	NA	NA	NA	NA
AXU59400.1\|249256_250390_+\|protease	membrane-associated metalloprotease	NA	NA	NA	NA
AXU59401.1\|251305_252328_+	cell wall hydrolase	A0A0A8WF62	Clostridium_phage	4.3e-33	55.8
AXU59402.1\|252623_253544_+	aspartate carbamoyltransferase catalytic chain	M1HWF9	Paramecium_bursaria_Chlorella_virus	7.1e-59	42.5
AXU59403.1\|253582_254275_+	dihydroorotate dehydrogenase electron transfer subunit	NA	NA	NA	NA
AXU59404.1\|254267_255170_+	dihydroorotate dehydrogenase 1B	NA	NA	NA	NA
AXU59405.1\|255254_255839_+	orotate phosphoribosyltransferase	Q58MW1	Prochlorococcus_phage	2.2e-05	28.1
AXU59406.1\|256053_256980_+	ketopantoate reductase	NA	NA	NA	NA
AXU59407.1\|257031_257922_-	LysR family transcriptional regulator	NA	NA	NA	NA
AXU59408.1\|258109_259141_+	membrane protein	NA	NA	NA	NA
AXU59409.1\|259434_260310_+	DNA glycosylase	NA	NA	NA	NA
AXU59410.1\|260327_261818_+	cardiolipin synthetase	NA	NA	NA	NA
AXU59411.1\|262010_262295_+	10 kDa chaperonin	A0A221S4A8	uncultured_virus	1.4e-13	42.6
AXU59412.1\|262327_263956_+	60 kDa chaperonin	A0A240F779	uncultured_virus	5.8e-157	55.7
AXU59413.1\|264217_264958_+	NCAIR mutase-like protein	A0A288TYA6	Enterococcus_phage	4.0e-20	44.8
AXU59414.1\|265041_265776_+	hypothetical protein	NA	NA	NA	NA
AXU59415.1\|265805_266225_+	hypothetical protein	NA	NA	NA	NA
AXU59416.1\|266606_268142_+	GMP synthase	A0A1V0SH76	Hokovirus	1.2e-23	33.7
AXU59417.1\|268680_270111_+	membrane-associated nucleotidase	NA	NA	NA	NA
AXU59418.1\|270258_270567_-	LysR family transcriptional regulator	NA	NA	NA	NA
AXU59419.1\|270603_271125_+	chromate transporter	NA	NA	NA	NA
AXU59420.1\|271244_272921_-	recombinase	A0A288WG52	Bacillus_phage	1.6e-29	32.0
AXU59421.1\|273015_273168_-	hypothetical protein	NA	NA	NA	NA
AXU59422.1\|273624_273864_-	conjugative transposon protein	A0A1S5SEX1	Streptococcus_phage	3.6e-23	69.7
AXU59423.1\|273860_274280_-	conjugative transposon regulatory protein	A0A1S5SEW0	Streptococcus_phage	1.2e-37	56.2
AXU59424.1\|274732_275194_-	hypothetical protein	NA	NA	NA	NA
AXU59425.1\|275202_275982_-	lantibiotic ABC transporter permease	NA	NA	NA	NA
AXU59426.1\|275984_276770_-	lantibiotic ABC transporter permease	NA	NA	NA	NA
AXU59427.1\|276762_277689_-	lantibiotic ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.1e-42	44.2
AXU59428.1\|277826_278744_-	two-component sensor histidine kinase	A0A2K9L114	Tupanvirus	8.7e-09	27.2
AXU59429.1\|278750_279443_-	two-component response regulator	W8CYM9	Bacillus_phage	2.4e-35	34.1
AXU59430.1\|279784_280162_+	conjugative transposon protein	A0A1S5SFA6	Streptococcus_phage	8.5e-19	46.7
AXU59431.1\|280220_281129_-	conjugative transposon exported protein	A0A1S5SF22	Streptococcus_phage	2.9e-113	66.8
AXU59432.1\|281145_282150_-	cell wall hydrolase	A0A1S5SEZ8	Streptococcus_phage	3.4e-139	80.2
AXU59433.1\|282146_284528_-	conjugative transposon membrane protein	A0A1S5SF30	Streptococcus_phage	2.1e-219	81.0
AXU59434.1\|284527_285364_-	conjugative transposon ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	1.6e-142	93.5
AXU59435.1\|285581_287408_-	group II intron reverse transcriptase/mutarase	H7BVW2	unidentified_phage	3.7e-11	26.8
AXU59436.1\|288104_289658_-	conjugative transposon ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	2.8e-241	83.7
AXU59437.1\|289641_290088_-	conjugative transposon membrane protein	A0A1S5SEX7	Streptococcus_phage	8.4e-58	77.7
AXU59438.1\|290084_290480_-	hypothetical protein	NA	NA	NA	NA
AXU59439.1\|291018_292425_-	conjugative transposon replication initiation factor	A0A1S5SEX3	Streptococcus_phage	1.8e-186	78.3
AXU59440.1\|292394_293792_-	conjugative transposon-related FtsK/SpoIII-relatd protein	A0A1S5SFB5	Streptococcus_phage	2.9e-205	77.7
AXU59441.1\|293830_294208_-	conjugative transposon protein	A0A1S5SF96	Streptococcus_phage	5.1e-48	79.7
AXU59442.1\|294389_294641_-	hypothetical protein	NA	NA	NA	NA
AXU59443.1\|294656_295724_-	DNA-cytosine methyltransferase	A0A2K9V3X0	Faecalibacterium_phage	2.1e-30	56.0
AXU59444.1\|296074_296908_-	Alpha/beta hydrolase family protein	NA	NA	NA	NA
AXU59445.1\|297092_300521_-	DNA repair protein	A0A1B1IVR3	uncultured_Mediterranean_phage	1.1e-176	37.4
AXU59446.1\|300839_303074_+	signaling protein	NA	NA	NA	NA
AXU59447.1\|303329_305360_+	transcription antiterminator	NA	NA	NA	NA
AXU59448.1\|305356_305809_+	PTS system transporter subunit IIA	NA	NA	NA	NA
AXU59449.1\|305810_306866_+	fructose-like permease EIIC subunit 2	NA	NA	NA	NA
AXU59450.1\|306932_307241_+	PTS system fructose-like transporter subunit EIIB	NA	NA	NA	NA
AXU59451.1\|307344_308610_+	sugar-phosphate kinase	NA	NA	NA	NA
AXU59452.1\|308697_309411_+	hydrolase	NA	NA	NA	NA
AXU59453.1\|309843_310569_+\|holin	CTP:phosphocholine cytidylyltransferase	NA	NA	NA	NA
AXU59454.1\|310586_312650_+\|holin	choline sulfatase	NA	NA	NA	NA
AXU59455.1\|312873_313167_-\|coat	spore coat protein	NA	NA	NA	NA
AXU59456.1\|313172_313388_-	hypothetical protein	NA	NA	NA	NA
AXU59457.1\|313836_314235_+\|transposase	transposase	A0A0A8WIU6	Clostridium_phage	2.5e-69	96.2
AXU59458.1\|314231_315395_+\|transposase	transposase	A0A0A8WI33	Clostridium_phage	1.7e-219	99.0
AXU59459.1\|315778_316291_-	nitroreductase	A0A1V0E011	Clostridioides_phage	3.5e-84	87.6
AXU59460.1\|316740_317217_+	phosphoribosylaminoimidazole carboxylase catalytic subunit	A0A2P0VNU7	Tetraselmis_virus	6.9e-26	45.8
AXU59461.1\|317222_317921_+	phosphoribosylaminoimidazole-succinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	1.5e-45	43.9
AXU59462.1\|317932_319300_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.6e-49	31.0
AXU59463.1\|319293_320370_+	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	2.2e-64	42.2
AXU59464.1\|320363_320957_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.3e-25	40.4
AXU59465.1\|320949_322482_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	2.3e-38	49.7
AXU59466.1\|322492_323743_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
AXU59467.1\|323767_327574_+	formylglycinamidine ribonucleotide synthetase	A6N228	Microbacterium_phage	1.0e-31	24.5

DBSCAN-SWA_2

502160 : 522622

Streptococcus_phage(94.12%)

integrase

attL 500701:500715|attR 527659:527673

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
500701:500715	attL	NA	NA	NA	NA
AXU59631.1\|502160_503429_-\|integrase	integrase	A0A1S5SEW7	Streptococcus_phage	1.5e-155	67.3
AXU59632.1\|503428_503632_-	excisionase	A0A1S5SF07	Streptococcus_phage	2.5e-25	82.1
AXU59633.1\|504006_504246_-	conjugative transposon excisionase	NA	NA	NA	NA
AXU59634.1\|504238_504919_-	conjugative transposon protein	A0A1S5SEW0	Streptococcus_phage	3.9e-22	43.1
AXU59635.1\|504946_505171_-	hypothetical protein	NA	NA	NA	NA
AXU59636.1\|505202_505628_-	hypothetical protein	NA	NA	NA	NA
AXU59637.1\|506026_506290_+	plasmid protein	A0A1X9I6D5	Streptococcus_phage	4.4e-22	83.1
AXU59638.1\|506518_507256_+	rRNA adenine N-6-methyltransferase	E4ZFQ0	Streptococcus_phage	7.0e-134	99.2
AXU59639.1\|507863_508280_-	hypothetical protein	NA	NA	NA	NA
AXU59640.1\|508276_508480_-	XRE family transcriptional regulator	NA	NA	NA	NA
AXU59641.1\|508580_509492_-	conjugative transposon protein	A0A1S5SF22	Streptococcus_phage	2.2e-84	53.6
AXU59642.1\|509509_510517_-	cell wall hydrolase	A0A1S5SEZ8	Streptococcus_phage	6.4e-130	67.6
AXU59643.1\|510513_512718_-	conjugative transposon protein	A0A1S5SF30	Streptococcus_phage	1.6e-181	51.1
AXU59644.1\|512717_515168_-	conjugative transposon protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	76.4
AXU59645.1\|515145_515544_-	conjugative transposon protein	A0A1S5SEX7	Streptococcus_phage	4.1e-48	73.0
AXU59646.1\|515660_516164_-	conjugative transposon protein	A0A1S5SF25	Streptococcus_phage	7.5e-55	60.8
AXU59647.1\|516181_516685_-	conjugative tansposon protein	NA	NA	NA	NA
AXU59648.1\|517009_517630_-	hypothetical protein	NA	NA	NA	NA
AXU59649.1\|517719_517941_-	conjugative transposon protein	A0A1S5SEY0	Streptococcus_phage	9.0e-29	87.7
AXU59650.1\|517941_518076_-	conjugative transposon protein	NA	NA	NA	NA
AXU59651.1\|518088_519285_-	conjugative transposon replication initiation factor	A0A1S5SEX3	Streptococcus_phage	4.7e-148	62.3
AXU59652.1\|519468_520863_-	conjugative transposon FtsK/SpoIIIE-like protein	A0A1S5SFB5	Streptococcus_phage	3.3e-177	65.7
AXU59653.1\|520931_521135_-	transcriptional regulator	A0A1V0E021	Clostridioides_phage	7.5e-06	45.8
AXU59654.1\|521138_521780_-	hypothetical protein	NA	NA	NA	NA
AXU59655.1\|521896_522280_-	conjugative transposon protein	A0A1S5SF96	Streptococcus_phage	2.3e-32	55.9
AXU59656.1\|522295_522622_-	conjugative transposon protein	A0A1S5SF38	Streptococcus_phage	1.5e-24	52.4
527659:527673	attR	NA	NA	NA	NA

DBSCAN-SWA_3

710070 : 759373

Streptococcus_phage(44.44%)

protease,transposase,coat,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXU59811.1\|710070_711990_+\|tRNA	threonyl-tRNA synthetase	A0A2K9L297	Tupanvirus	1.3e-144	39.9
AXU59812.1\|712757_713849_+\|transposase	PD-(D/E)XK nuclease family transposase	NA	NA	NA	NA
AXU59813.1\|714514_715855_+	two-component sensor histidine kinase	X5JAC0	Clostridium_phage	1.5e-78	38.6
AXU59814.1\|716567_717137_-	putative HD superfamily hydrolase	NA	NA	NA	NA
AXU59815.1\|717297_718548_-	efflux protein	NA	NA	NA	NA
AXU59816.1\|718838_719417_-	TetR family transcriptional regulator	NA	NA	NA	NA
AXU59817.1\|719754_721215_+	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
AXU59818.1\|721588_722194_+	TetR family transcriptional regulator	NA	NA	NA	NA
AXU59819.1\|722196_724764_+	PEP-utilizing kinase	A0A1V0SGR7	Hokovirus	9.2e-48	39.2
AXU59820.1\|725187_725334_-	hypothetical protein	NA	NA	NA	NA
AXU59821.1\|725381_726611_-	signaling protein	NA	NA	NA	NA
AXU59822.1\|726612_727791_-	signaling protein	G3MA91	Bacillus_virus	1.9e-08	27.3
AXU59823.1\|728948_730415_+	GntR family transcriptional regulator	NA	NA	NA	NA
AXU59824.1\|730699_730879_+	hypothetical protein	NA	NA	NA	NA
AXU59825.1\|731515_731791_+	hypothetical protein	NA	NA	NA	NA
AXU59826.1\|731810_732098_+	hypothetical protein	NA	NA	NA	NA
AXU59827.1\|732790_735286_+	hypothetical protein	NA	NA	NA	NA
AXU59828.1\|735300_740511_+	hypothetical protein	NA	NA	NA	NA
AXU59829.1\|740735_742835_-	cation transporting ATPase	E4ZFI9	Streptococcus_phage	1.7e-71	29.5
AXU59830.1\|742877_743273_-	hypothetical protein	NA	NA	NA	NA
AXU59831.1\|744287_744476_+	hypothetical protein	NA	NA	NA	NA
AXU59832.1\|744659_745100_-	hypothetical protein	NA	NA	NA	NA
AXU59833.1\|745454_746768_+	putative phosphoadenosine phosphosulfate sulfotransferase	A0A220GKF8	Streptococcus_phage	2.8e-93	40.8
AXU59834.1\|746785_747322_+	ParB-like nuclease domain protein	A0A220GKT8	Streptococcus_phage	1.2e-63	69.7
AXU59835.1\|747837_748059_+\|coat	Spore coat associated protein JA (CotJA)	NA	NA	NA	NA
AXU59836.1\|748058_748322_+\|coat	spore-coat protein	NA	NA	NA	NA
AXU59837.1\|748383_748956_+\|coat	spore-coat protein	NA	NA	NA	NA
AXU59838.1\|749832_750183_-	hypothetical protein	NA	NA	NA	NA
AXU59839.1\|750499_751033_+	methylated-DNA--protein-cysteine methyltransferase 1	M1PFU9	Streptococcus_phage	1.2e-34	49.4
AXU59840.1\|752045_752642_-	hypothetical protein	NA	NA	NA	NA
AXU59841.1\|753107_753521_+	hypothetical protein	NA	NA	NA	NA
AXU59842.1\|753593_754130_+	glutamate-rich protein GrpB	NA	NA	NA	NA
AXU59843.1\|754289_754955_+	chloride channel protein	NA	NA	NA	NA
AXU59844.1\|755609_756719_+\|transposase	transposase-like protein B	A0A0H3UZC2	Geobacillus_virus	9.6e-111	53.5
AXU59845.1\|756845_757748_+	Voltage gated chloride channel family protein	NA	NA	NA	NA
AXU59846.1\|758359_759373_+\|protease	membrane-associated metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_4

1475612 : 1499999

Clostridium_phage(54.55%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXU60475.1\|1475612_1475813_+	cold shock protein	A0A1W6JNX5	Morganella_phage	2.7e-16	66.2
AXU60476.1\|1476233_1476662_+	regulatory protein	NA	NA	NA	NA
AXU60477.1\|1476804_1477560_-	peptidyl-prolyl isomerase	NA	NA	NA	NA
AXU60478.1\|1477680_1478097_-	hypothetical protein	NA	NA	NA	NA
AXU60479.1\|1478260_1478767_-	phage protein	A0A0A8WEK1	Clostridium_phage	4.0e-56	67.1
AXU60480.1\|1478848_1479169_-	phage repressor	A0A0A8WE28	Clostridium_phage	3.7e-23	54.5
AXU60481.1\|1479337_1479535_+	phage regulatory protein	NA	NA	NA	NA
AXU60482.1\|1479639_1480080_+	DNA-binding protein	A0A090EUN5	Clostridium_phage	6.0e-32	51.4
AXU60483.1\|1480328_1480772_+	hypothetical protein	A0A1V0DZX9	Clostridioides_phage	2.2e-18	36.1
AXU60484.1\|1480776_1481841_+	phage-like element pbsx protein xkdK	A0A1V0DZX4	Clostridioides_phage	4.4e-97	53.1
AXU60485.1\|1481854_1482283_+	phage-like element pbsx protein XkdM	A0A1V0DZX1	Clostridioides_phage	2.8e-34	51.8
AXU60486.1\|1482396_1482843_+	Phage XkdN-like protein	A0A090EUD0	Clostridium_phage	8.2e-13	36.0
AXU60487.1\|1482869_1483037_+	hypothetical protein	NA	NA	NA	NA
AXU60488.1\|1483036_1485490_+	phage protein	A0A1V0DZX3	Clostridioides_phage	6.1e-17	55.7
AXU60489.1\|1485489_1485912_+	phage-like element pbsx protein xkdP	A0A090DBR9	Clostridium_phage	1.7e-52	71.1
AXU60490.1\|1486193_1487723_+	phage cell wall hydrolase	A0A1V0DZX6	Clostridioides_phage	2.9e-243	80.9
AXU60491.1\|1487738_1488065_+	hypothetical protein	J9QE86	Clostridium_phage	1.0e-52	94.4
AXU60492.1\|1488064_1488493_+	phage protein	A0A0A8WJ32	Clostridium_phage	5.8e-64	82.4
AXU60493.1\|1488485_1489538_+	phage protein	A0A0A8WFP3	Clostridium_phage	2.7e-139	71.0
AXU60494.1\|1489534_1490233_+	phage protein	A0A090D815	Clostridium_phage	5.5e-48	56.9
AXU60495.1\|1490233_1491220_+\|tail	phage tail fiber protein	A0A2H4J039	uncultured_Caudovirales_phage	3.4e-59	45.8
AXU60496.1\|1491241_1496419_+	RCC1 domain-containing protein, alpha-tubulin suppressor	A0A0A8WEY5	Clostridium_phage	6.5e-77	26.7
AXU60497.1\|1496435_1496789_+	hypothetical protein	A0A0A8WJF2	Clostridium_phage	7.2e-12	42.1
AXU60498.1\|1497051_1497312_+	hypothetical protein	E2ELK7	Clostridium_phage	9.9e-35	90.6
AXU60499.1\|1497532_1497988_-	hypothetical protein	NA	NA	NA	NA
AXU60500.1\|1498215_1498635_-	phage regulatory protein	S5MUV6	Brevibacillus_phage	5.4e-06	37.2
AXU60501.1\|1498933_1499143_+	phage regulatory protein	Q5YAA3	Bacillus_phage	5.9e-06	47.2
AXU60502.1\|1499174_1499384_+	hypothetical protein	NA	NA	NA	NA
AXU60503.1\|1499600_1499999_-	phage regulatory protein	A0A1L2JY18	Aeribacillus_phage	2.7e-07	29.7

DBSCAN-SWA_5

1580224 : 1589951

Pandoravirus(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXU60572.1\|1580224_1580809_+	para-aminobenzoate synthase glutamine amidotransferase component II	A0A0P0IKJ1	Acinetobacter_phage	1.4e-57	52.6
AXU60573.1\|1580810_1582160_+	para-aminobenzoate synthase component I	S4VNU7	Pandoravirus	2.2e-37	41.2
AXU60574.1\|1582149_1582893_+	aminodeoxychorismate lyase	NA	NA	NA	NA
AXU60575.1\|1582926_1583628_+	hypothetical protein	NA	NA	NA	NA
AXU60576.1\|1583653_1584226_+	GTP cyclohydrolase I	E7DN69	Pneumococcus_phage	3.0e-44	51.6
AXU60577.1\|1584289_1585081_+	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	1.1e-23	28.8
AXU60578.1\|1585091_1585457_+	dihydroneopterin aldolase	NA	NA	NA	NA
AXU60579.1\|1585449_1585956_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase	S4VNV0	Pandoravirus	2.7e-12	35.2
AXU60580.1\|1585936_1586722_+	chorismate biosynthesis-like protein	E3T537	Cafeteria_roenbergensis_virus	1.7e-13	27.9
AXU60581.1\|1586976_1588767_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.2e-51	32.6
AXU60582.1\|1588784_1589951_+	RNA polymerase sigma factor (sigma-43)	M4SMP8	Cyanophage	9.6e-37	36.8

DBSCAN-SWA_6

1893900 : 1913981

Streptococcus_phage(89.47%)

integrase

attL 1891465:1891478|attR 1903343:1903356

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1891465:1891478	attL	NA	NA	NA	NA
AXU60854.1\|1893900_1895118_-\|integrase	integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
AXU60855.1\|1895199_1895403_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
AXU60856.1\|1895863_1896094_-	conjugative transposon protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
AXU60857.1\|1896090_1896513_-	conjugative transposon regulatory protein	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
AXU60858.1\|1897017_1897371_+	conjugative transposon regulatory protein	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
AXU60859.1\|1897716_1899636_-	conjugative transposon tetracycline resistance protein	A0A2K5B2A5	Erysipelothrix_phage	0.0e+00	97.3
AXU60860.1\|1899887_1900823_-	conjugative transposon exported protein	A0A1S5SF22	Streptococcus_phage	7.7e-170	99.0
AXU60861.1\|1900819_1901821_-	cell wall hydrolase	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
AXU60862.1\|1901817_1903995_-	conjugative transposon membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
1903343:1903356	attR	NA	NA	NA	NA
AXU60863.1\|1903997_1904915_-	conjugative transposon ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	5.4e-168	99.7
AXU60864.1\|1905048_1906875_-	group II intron reverse transcriptase/mutarase	H7BVW2	unidentified_phage	3.7e-11	26.8
AXU60865.1\|1907571_1908678_-	conjugative transposon ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	6.3e-187	100.0
AXU60866.1\|1908726_1909125_-	conjugative transposon ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	4.2e-69	100.0
AXU60867.1\|1909589_1910087_-	conjugative transposon protein	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
AXU60868.1\|1910203_1910425_-	conjugative transposon protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
AXU60869.1\|1910467_1911673_-	conjugative transposon replication initiation factor	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
AXU60870.1\|1911850_1913236_-	conjugative transposon FtsK/SpoIIIE family protein	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
AXU60871.1\|1913264_1913648_-	conjugative transposon protein	A0A1S5SF96	Streptococcus_phage	2.3e-64	100.0
AXU60872.1\|1913666_1913981_-	conjugative transposon protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0

DBSCAN-SWA_7

2527803 : 2533825

Clostridium_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXU61426.1\|2527803_2528169_-	phage-related regulatory protein	A0A2R2ZGW3	Clostridioides_phage	3.2e-39	67.5
AXU61427.1\|2528288_2528441_-	hypothetical protein	X5JAJ2	Clostridium_phage	1.6e-05	59.2
AXU61428.1\|2529755_2530640_-	hypothetical protein	NA	NA	NA	NA
AXU61429.1\|2530833_2530986_-	hypothetical protein	J9QED5	Clostridium_phage	9.6e-06	52.0
AXU61430.1\|2531259_2531592_-	hypothetical protein	NA	NA	NA	NA
AXU61431.1\|2531618_2531873_-	hypothetical protein	NA	NA	NA	NA
AXU61432.1\|2532021_2532453_-\|transposase	transposase-like protein B	A0A0H3UZC2	Geobacillus_virus	3.4e-32	63.7
AXU61433.1\|2533151_2533343_-	repressor	A0A0A8WFF9	Clostridium_phage	1.9e-14	68.9
AXU61434.1\|2533447_2533825_-	regulatory protein	A0A0A8WJU1	Clostridium_phage	1.8e-53	90.4

DBSCAN-SWA_8

3086868 : 3095821

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXU61904.1\|3086868_3088782_-	capsular polysaccharide biosynthesis protein	A0A1V0SAI8	Catovirus	1.1e-26	29.8
AXU61905.1\|3088865_3089957_-	capsular polysaccharide biosynthesis glycosyl transferase	A0A1V0SL50	Klosneuvirus	1.8e-16	26.2
AXU61906.1\|3089962_3091258_-	UDP-glucose 6-dehydrogenase	A0A127AXI2	Bacillus_phage	2.9e-90	43.6
AXU61907.1\|3091283_3092036_-	teichuronic acid biosynthesis glycosyl transferase	A0A1V0SAH6	Catovirus	4.6e-16	40.5
AXU61908.1\|3092083_3092992_-	beta-glycosyltransferase	NA	NA	NA	NA
AXU61909.1\|3093013_3093763_-	teichuronic acid biosynthesis glycosyl transferase	A0A1V0SAH6	Catovirus	1.2e-16	38.8
AXU61910.1\|3093791_3094967_-	minor teichoic acid biosynthesis protein	NA	NA	NA	NA
AXU61911.1\|3094981_3095821_-	glycosyl transferase	A0A2P1ELT8	Moumouvirus	7.0e-05	26.3

DBSCAN-SWA_9

3668733 : 3728585

Agrobacterium_phage(15.38%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXU62373.1\|3668733_3669813_-\|protease	protease	A0A1B1IT49	uncultured_Mediterranean_phage	3.3e-15	25.7
AXU62374.1\|3669968_3671318_-	glucose-6-phosphate isomerase	NA	NA	NA	NA
AXU62375.1\|3671582_3673211_-	sodium-dependent phosphate transporter	NA	NA	NA	NA
AXU62376.1\|3673334_3674939_-	FAD-dependent dehydrogenase	NA	NA	NA	NA
AXU62377.1\|3674986_3675304_-	hypothetical protein	NA	NA	NA	NA
AXU62378.1\|3675308_3675674_-	hypothetical protein	NA	NA	NA	NA
AXU62379.1\|3675754_3676792_-	protein translocase	NA	NA	NA	NA
AXU62380.1\|3677044_3677629_-	hypothetical protein	NA	NA	NA	NA
AXU62381.1\|3677643_3678087_-	hypothetical protein	NA	NA	NA	NA
AXU62382.1\|3678087_3678960_-	fimbrial assembly protein	NA	NA	NA	NA
AXU62383.1\|3679012_3679372_-	type IV pilin	NA	NA	NA	NA
AXU62384.1\|3679425_3680511_-	type IV pilus-assembly protein	NA	NA	NA	NA
AXU62385.1\|3680681_3682031_-	type IV pilus-assembly protein	NA	NA	NA	NA
AXU62386.1\|3682053_3682734_-	membrane protein	NA	NA	NA	NA
AXU62387.1\|3683125_3684205_-	ATP/GTP-binding protein	NA	NA	NA	NA
AXU62388.1\|3684782_3686153_+	transporter	NA	NA	NA	NA
AXU62389.1\|3686417_3687029_-	ribosome biogenesis GTP-binding protein YsxC	NA	NA	NA	NA
AXU62390.1\|3687018_3689382_-\|protease	ATP-dependent protease La	A0A0R6PGP8	Moraxella_phage	4.0e-175	44.4
AXU62391.1\|3689561_3690074_+	chromate transport protein	NA	NA	NA	NA
AXU62392.1\|3690061_3690589_+	chromate transport protein	NA	NA	NA	NA
AXU62393.1\|3690659_3691910_-\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	6.1e-146	63.1
AXU62394.1\|3691928_3692513_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	9.3e-57	58.8
AXU62395.1\|3692662_3693949_-	trigger factor	NA	NA	NA	NA
AXU62396.1\|3694142_3694613_-	phosphoesterase	NA	NA	NA	NA
AXU62397.1\|3694612_3695962_-	ribonuclease PH	NA	NA	NA	NA
AXU62398.1\|3696121_3698146_-	DNA ligase	A0A0K2QQN8	Ralstonia_phage	3.8e-113	37.6
AXU62399.1\|3698331_3699270_-	D-isomer specific 2-hydroxyacid dehydrogenase	NA	NA	NA	NA
AXU62400.1\|3699371_3699794_-	hypothetical protein	NA	NA	NA	NA
AXU62401.1\|3699981_3701265_+	transporter	NA	NA	NA	NA
AXU62402.1\|3701342_3701858_-	electron transport protein	NA	NA	NA	NA
AXU62403.1\|3701857_3703234_-	hydrogenase	NA	NA	NA	NA
AXU62404.1\|3703258_3703810_-	electron transport protein	NA	NA	NA	NA
AXU62405.1\|3703867_3704083_-	hypothetical protein	NA	NA	NA	NA
AXU62406.1\|3704051_3704885_-	formate dehydrogenase accessory protein	NA	NA	NA	NA
AXU62407.1\|3707328_3708387_-	ABC transporter permease	NA	NA	NA	NA
AXU62408.1\|3708597_3709257_-	two-component response regulator	W8CYM9	Bacillus_phage	4.2e-29	33.6
AXU62409.1\|3709562_3710192_+	hypothetical protein	NA	NA	NA	NA
AXU62410.1\|3710218_3710587_+	hypothetical protein	NA	NA	NA	NA
AXU62411.1\|3710671_3711460_-	ABC-2 family transporter protein	NA	NA	NA	NA
AXU62412.1\|3711460_3712333_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.0e-27	34.8
AXU62413.1\|3712347_3714057_-	hypothetical protein	NA	NA	NA	NA
AXU62414.1\|3714203_3714785_-	accessory gene regulator protein	X5JB40	Clostridium_phage	2.9e-18	30.4
AXU62415.1\|3714843_3714984_-	autoinducer prepeptide	NA	NA	NA	NA
AXU62416.1\|3714995_3716312_-	sensor histidine kinase VirS	X5JAC0	Clostridium_phage	3.4e-54	33.2
AXU62417.1\|3716305_3717016_-	LytR family DNA-binding response regulator	A0A2R2ZGH8	Clostridioides_phage	2.2e-28	36.2
AXU62418.1\|3717454_3718030_-	hypothetical protein	NA	NA	NA	NA
AXU62419.1\|3718322_3718601_-	Mor transcription activator domain-containing protein	NA	NA	NA	NA
AXU62420.1\|3718909_3719671_-	iron-sulfur cluster-binding protein	NA	NA	NA	NA
AXU62421.1\|3719839_3721900_-	exosporium glycoprotein	A0A285PXU9	Cedratvirus	1.9e-40	65.5
AXU62422.1\|3721978_3723055_-	glycosyl transferase	A0A1V0SAJ8	Catovirus	1.3e-16	25.3
AXU62423.1\|3723366_3723951_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	3.6e-48	51.3
AXU62424.1\|3723947_3724430_-	AraC family transcription regulator	NA	NA	NA	NA
AXU62425.1\|3724628_3726044_-	GntR family transcriptional regulator	NA	NA	NA	NA
AXU62426.1\|3726158_3726827_+	B3/4 domain protein	NA	NA	NA	NA
AXU62427.1\|3727002_3727521_-	nitroreductase	NA	NA	NA	NA
AXU62428.1\|3727672_3727996_+	transcriptional regulator	NA	NA	NA	NA
AXU62429.1\|3728000_3728585_-\|protease	protease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP012321

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection