CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP026672	Leptospira borgpetersenii serovar Ceylonica strain Piyasena chromosome 2, complete sequence	0 crisprs	csa3	0	0	0	0
CP026671	Leptospira borgpetersenii serovar Ceylonica strain Piyasena chromosome 1, complete sequence	4 crisprs	cas3,WYL,cas2,cas1,cas6e,cas7,cse2gr11,cas8e,Cas9_archaeal,csa3,DinG	0	9	0	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP026671_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026671_1

631476-631572

Orphan

Consensus_repeat	Method
CCGCGACGACCATAGAGAGTCGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026671_1

>merge|CP026671|1|631476-631572|CRISPRCasFinder
CCGCGACGACCATAGAGAGTCGTGGCGCTGAGTTTCCCCGCGACGACCATAGGAGTCGTGGCGCTGAGTTTCCCCGCGACGACCATAGAGAGTCGGC

>CP026671|1|1|631476-631572|CRISPRCasFinder
CCGCGACGACCATAGAGAGTCGTG	GCGCTGAGTTTCCCCGCGACGACCATAGGAGTCGTGGCGCTGAGTTTCC
CCGCGACGACCATAGAGAGTCGGC

Protein	Signature genes	Signature genes Name	Protein_function
CP026671.1\|AXX14680.1\|631637_632855_-\|aspartate-kinase	unknown	unknown	gnl\|CDD\|235843
CP026671.1\|AXX14686.1\|639702_641511_-\|WGR-domain-containing-protein	unknown	unknown	gnl\|CDD\|275380
CP026671.1\|AXX17119.1\|642621_643482_+\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|238329
CP026671.1\|AXX14681.1\|633033_634848_+\|sodium-transporter	unknown	unknown	gnl\|CDD\|271371
CP026671.1\|AXX14684.1\|637820_638738_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|366166
CP026671.1\|AXX17117.1\|621979_623554_-\|spore-coat-biosynthesis-protein-F	unknown	unknown	gnl\|CDD\|133011
CP026671.1\|AXX14672.1\|618455_621104_-\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
CP026671.1\|AXX14685.1\|638935_639436_-\|peptide-methionine-(R)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|234692
CP026671.1\|AXX14676.1\|625116_626151_-\|putative-peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|200393
CP026671.1\|AXX14673.1\|621213_621438_+\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX14677.1\|626211_628287_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
CP026671.1\|AXX14683.1\|636310_637060_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|234640
CP026671.1\|AXX14679.1\|630879_631281_+\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX17118.1\|637138_637660_+\|endonuclease	unknown	unknown	gnl\|CDD\|340813
CP026671.1\|AXX14687.1\|641775_642390_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
CP026671.1\|AXX14678.1\|628471_630556_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
CP026671.1\|AXX14675.1\|623528_625067_-\|spiro-SPASM-protein	unknown	unknown	gnl\|CDD\|275125
CP026671.1\|AXX14671.1\|617185_618466_-\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|184327
CP026671.1\|AXX14674.1\|621710_621902_+\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX14682.1\|635484_636105_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378734

Protein	Function_ID	Function_description	E-value
CP026671.1\|AXX14680.1\|631637_632855_-\|aspartate-kinase	gnl\|CDD\|235843	PRK06635, PRK06635, aspartate kinase; Reviewed.	0
CP026671.1\|AXX14686.1\|639702_641511_-\|WGR-domain-containing-protein	gnl\|CDD\|275380	sd00033, LRR_RI, leucine-rich repeats, ribonuclease inhibitor (RI)-like subfamily. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	2.92734e-28
CP026671.1\|AXX14685.1\|638935_639436_-\|peptide-methionine-(R)-S-oxide-reductase	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	1.52557e-89
CP026671.1\|AXX14675.1\|623528_625067_-\|spiro-SPASM-protein	gnl\|CDD\|275125	TIGR04321, hypothetical_protein_TresaDRAFT_0163, spiro-SPASM protein. This three-domain protein is restricted to the spirochetes and widely distributed (excepting Borrelia). It has a conserved C-terminal SPASM domain, a 4Fe-4S binding domain shared by a number of peptide-modifying and heme-modifying radical SAM proteins. It has a central radical SAM domain, although half the members have lost the signature 4Fe-4S-binding Cys residues, fail to register with the radical SAM domain definition of pfam04055, and must be considered pseudo-SAM proteins. PSI-BLAST shows a relationship between the N-terminal domain and various predicted glycosyltransferases (e.g. Bacillus subtilis SpsF) and cytidyltransferases. In some Treponema species, this protein appears to split into two tandem genes.	0
CP026671.1\|AXX14684.1\|637820_638738_-\|alpha/beta-hydrolase	gnl\|CDD\|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	1.45875e-11
CP026671.1\|AXX17117.1\|621979_623554_-\|spore-coat-biosynthesis-protein-F	gnl\|CDD\|133011	cd02518, GT2_SpsF, SpsF is a glycosyltrnasferase implicated in the synthesis of the spore coat. Spore coat polysaccharide biosynthesis protein F (spsF) is a glycosyltransferase implicated in the synthesis of the spore coat in a variety of bacteria challenged by stress as starvation. The spsF gene is expressed in the late stage of coat development responsible for a terminal step in coat formation that involves the glycosylation of the coat. SpsF gene mutation resulted in spores that appeared normal. But, the spores tended to aggregate and had abnormal adsorption properties, indicating a surface alteration.	4.03011e-68
CP026671.1\|AXX14672.1\|618455_621104_-\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
CP026671.1\|AXX17119.1\|642621_643482_+\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|238329	cd00586, 4HBT, 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites. There is no evidence to suggest that 4HBT is related to the type I thioesterases functioning in primary or secondary metabolic pathways. Each subunit of the 4HBT tetramer adopts a so-called hot-dog fold similar to those of beta-hydroxydecanoyl-ACP dehydratase, (R)-specific enoyl-CoA hydratase, and type II, thioesterase (TEII).	1.93573e-09
CP026671.1\|AXX14676.1\|625116_626151_-\|putative-peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|200393	TIGR04142, PCisTranLspir, putative peptidyl-prolyl cis-trans isomerase, LIC12922 family. Members of this protein family have a known crystal structure (3NRK) showing similarity to the peptidyl-prolyl cis-trans isomerase SurA. Members are found in Leptospira species next to an uncharacterized radical SAM enzyme and a cytidylyltransferase family protein.	8.85711e-105
CP026671.1\|AXX14677.1\|626211_628287_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.52227e-57
CP026671.1\|AXX14683.1\|636310_637060_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|234640	PRK00110, PRK00110, YebC/PmpR family DNA-binding transcriptional regulator.	7.27398e-130
CP026671.1\|AXX17118.1\|637138_637660_+\|endonuclease	gnl\|CDD\|340813	cd16962, RuvC, Crossover junction endodeoxyribonuclease RuvC. Crossover junction endodeoxyribonuclease RuvC is also called Holliday junction resolvase RuvC. It is part of the RuvABC pathway in Escherichia coli and other Gram-negative bacteria that is involved in processing Holliday junctions, which are formed by the reciprocal exchange of strands between two DNA duplexes. Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. RuvC is thought to bind either on the open, DNA exposed face of a single RuvA tetramer, or to replace one of the two tetramers. Binding is proposed to be mediated by an unstructured loop on RuvC, which becomes structured on binding RuvA. RuvC can be bound to the complex in either orientation, therefore resolving Holliday junctions in either a horizontal or vertical manner. HJRs occur in archaea, bacteria, and in the mitochondria of certain fungi. These are referred to as the RuvC family of Holliday junction resolvases, RuvC being the Escherichia coli HJR. RuvC and its orthologs are homodimers and display structural similarity to RNase H and Hsp70.	2.29059e-48
CP026671.1\|AXX14687.1\|641775_642390_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	7.68087e-12
CP026671.1\|AXX14678.1\|628471_630556_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	3.84591e-59
CP026671.1\|AXX14681.1\|633033_634848_+\|sodium-transporter	gnl\|CDD\|271371	cd11477, SLC5sbd_u1, Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain. SLC5 (also called the sodium/glucose cotransporter family or solute sodium symporter family) is a family of proteins that co-transports Na+ with sugars, amino acids, inorganic ions or vitamins. Prokaryotic members of this family include Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. One member of the SLC5 family, human SGLT3, has been characterized as a glucose sensor and not a transporter. This subfamily belongs to the solute carrier 5 (SLC5) transporter family.	9.59714e-152
CP026671.1\|AXX14671.1\|617185_618466_-\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|184327	PRK13789, PRK13789, phosphoribosylamine--glycine ligase; Provisional.	0
CP026671.1\|AXX14682.1\|635484_636105_-\|hypothetical-protein	gnl\|CDD\|378734	pfam11845, DUF3365, Protein of unknown function (DUF3365). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 198 to 657 amino acids in length.	3.01378e-26

>CP026671.1|AXX14679.1|630879_631281_+|hypothetical-protein
MSLSARKLLLQINGIALILASTVAFFALDILGIFFGKGPARFIFEGQEFVGIGFFEAHGLAFILGVLLFRAEPKRSWHIVAVAIHALLGTANILMWGIFIAVNSLPMGYGTTAMHWIFVFFQLLAVFHSTKED
>CP026671.1|AXX14678.1|628471_630556_-|methyl-accepting-chemotaxis-protein
MSIRFRISLYLSIVLFIGFGILATVNSYTAYKKLEQEVVNGSEVTAERWTMEIKDYLNTGMGIIRGFRFPLLFDSPPRNKVILALQEILKVNESYFGARVAYEPNGFDGQDSQFESTPGHDASGRFIPYLHRGKTDEEIVLEAAKYYDNPGPEGEWYQVPKKTLTQFVTDPYYYELDGKVKILMISLIAPFRVGNQFYGVGGLDYRLEELQKLIGGKKPFQGQGYLSLISPKGIYAVNGFDGNLVGKQIPDAQELAFYLKESQEETGKKFTTDSNGYTHYFFPFHIGKDKRFWTLQVSIPNSIYRAAIMSILFQSFVATILILLSVLLCVNFIFQRLISAGLLKAVGFSEEIASGNLVAQSSHDKKDEIGTLLGSMNQMRENLLKVLREIGGSAYTLRDTSEKMADSSRNFSDVAQTQASAAEESSAAVEELAASAQNVGKSMEKAVLSMKEIDGNVVRLKEQIVNINREMQDLVELAALSKEQGVTGENAMIESTSAMAAIGDSASRITEILSIITEISEKTNLLALNAAIEAARAGEAGKGFAVVAEEIGKLASQTSSSVQEIGSLVNSTNTAVLNGNTKVAEASNVLKKLREQVEEFDRYAKNVLASVKTQEENTKEISQSANELMTFSLQIEEAVLEQKRATDEITKTIMSISDGTQEIASGADDLTSFSGNIHGQAQNLGQLIGKFKTN
>CP026671.1|AXX14677.1|626211_628287_-|methyl-accepting-chemotaxis-protein
MSIRFRISLYLSIVLFIGFSILAAINSITTYKNLKSEVENNSTITSERWSLEVKDILDSAMFYARGFRSPLIFTSPPREAVITSIKEVIERNPNFFALWLVYEPDLYDGKDAQYRNTFGHDSTGRFVPYAFQSGEKGKARIRPNVGYENQDGTGDFYQIPKKNNTYYVSEPYRYKSDSVDTMMISIVAPISKDGFFRGACGIDLKAEELQKKFGEVKPFRNQGYMTLISPSGLYTVNGKDPSLIGNKIPDAQELEFYLKKSQEGKNFTYSSEAHTHYFFPFHVGKDKRFWTLQVSIPDSIYTDEMFNTIFSRALTAILILVSVLLCVNFIFQRLISAGLLKAVGFSEEIASGNLVAQSSHDKKDEIGTLLGSMNQMRESLLKVLREIGGSAKMLRDTSEKMADSSRNFSDVAQTQASAAEESSAAVEELAASAQNVGKSMEKAVLSMKEIDGNVVRLKEQIVNINREMQDLVELAALSKEQGVTGENAMIESTSAMAAIGDSASRITEILSIITEISEKTNLLALNAAIEAARAGEAGKGFAVVAEEIGKLASQTSSSVQEIGSLVNSTNTAVLNGNTKVAEASNVLKKLREQVEEFDRYAKNVLASVKTQEENTKEISQNANELMTFSLQIEEAVLEQKRATDEITKTIMSISDGTQEIASGAEDLTSFSGNMYGQAQNLGQLIGKFKTD
>CP026671.1|AXX14676.1|625116_626151_-|putative-peptidyl-prolyl-cis-trans-isomerase
MNSKQTYAKNFFFTGTFVFLFLQNPIQTAESLNRVIATVGTISISELDLDDASEKYTKLQKHLKHEDFRKSLRTRIIDFLIDRAIVDVVAEEESIQVNEQRVDAEIEKRMEVMGITNRKQFEKAMETSSGMPFELWVTELPYQIKKGQLLQLKIAVPPPSEQEIKSWYNQNRDKVGFEIRYRIISIAPENDSIQEENRLYKELSDIRKSVLADPSSFALIAGSPRNDPTLRSRRGMVEWISSFDLYKYSKITATIAAPLPNGGVSEVFRDERKRYSILKIEGKRPTPMENLRGGIQNILYRDKEEDTFYRWLKESRAEIPIQIFDEAYRKENKIPLKEETFHLD
>CP026671.1|AXX14675.1|623528_625067_-|spiro-SPASM-protein
MKFPIFHSAVFLSPETTSLLESASEGENLLFLSLRKLSKVLPESTVFFNAWPFPKRINTYNFLNIRILEDPSEISFVKKISSELPQSRTGDPDWDDASFFYFTGLFPCLDENLSLEIYRRHDLYLSQYSYSENLPSGIIPTILSREFTNGIPETANTSVQEYLGKNINHYDVEIFYHDPDLRQYRLDFSLKNKRSLSLVRGFLKSKEEWNYSDIHPWIQKHPEVFRTGPSYLELEVYRGCELSCSFCPRQFSSNDQDGSFLSPAFLENLLKQQEESFSNEYGVCFGGLGEPLLHPEFTKLLSTVFQISSPLLQELFIETALYTDLNSTLDFLNTLDSSFRQKITWIVNLTTRNQEKYNSLYGKKVLSRVFSNLEQLGNIFPKNRIYLQFLKIQETENEVEVWVDETEKQGYGVILQKYNRYAGLMPEKRVTDLTPIQREFCWHLNRDLYVNSDGTVSICKQTPGKVFGNLHKETLMQIWQKGLPSFADSLNGKHETTGAPCLNCDEWYTFNA
>CP026671.1|AXX17117.1|621979_623554_-|spore-coat-biosynthesis-protein-F
MSGIRSTRNIYAFIQARTGSARLPGKVLRELPSGSGKTLIDRIQDRIRVVLPEEQIVYLIPEADQELRSFLENRKYRFFTGDPLDVRLRYIKAAEFFKAEAILRLTGDNPFYDTLHLDQLLQSFQFTKPDLAYVTELPLGMGGEIFTRKALEWRPQVLEERHKEHVSLSIKENPHRFRITKLSSLLTEKEKQVLPKLRLTVDEPKDFETVSRIFNLLNDRNPFFGAKECIQLFEKEPNVFVGNQDVEQIRFQTQSTKITNQFRVGILVGDPKKFGSGHFERSRILFALLSAASYKTFWLEDFPADGELDLLVVDSRDIPIPEYSKTRIFLLDHFGPDRKKYGHYDLLPHPTISDRFSLDRILISPGLLNVDPISNSFLLCYAGSIHSSKELDFFLSSLLSKDKSLSQIVRVGGAPPVGNSIEFIPRVSRFQFQNLLASCSGFVSYFGQSLFEAVFLKKRICSYSISPIHSSLARFCEQKFGIPFAGELSSGGLDSNTELSVAFQSVSGEGYSLLLREIEEFLHS
>CP026671.1|AXX14674.1|621710_621902_+|hypothetical-protein
MKFVNLFLKCENYNKSRFDEQILKVRPLLIENSFSFFDAEFTLFKSVPNKTLKEISCNHSISP
>CP026671.1|AXX14673.1|621213_621438_+|hypothetical-protein
MNLHSKKVRKVRMKILLLRVRRLYGRHSCKLSETVFGCGDGPGNVFLKTDWPGSIQLIGGILYRIDARILGKDS
>CP026671.1|AXX14672.1|618455_621104_-|valine--tRNA-ligase
MKKQIGDRYEPKEVENKWISLWEEKKSFAPNSNSKESFSMVIPPPNVTGSLHIGHALNHTIQDILIRIERKKGKSTLWLPGMDHAGIATQMVVERELAKEGKKRTDFTREEFVNRIWEWKDHSGGMITRQQKLLGESVDWSRERFTLDEGLSKAVFKVFKSLYDEGLIYRGERIINWCPTSRTAISDLEVEFRETKGKLYHIKYPIHGKKNQFLVVATTRPETMFGDVAVCANPEDKRYVSFKDVVLDLPLTNRQIPLLFDSFVDQEFGSGLVKITPAHDANDFEAGQRLGLKPLLVMNPDGTMNVNAGPYQSLDRFEARRKVVADLEVKGLIEKIEDHVHSVGHNSRGGTVIEPYLSTQWFVKIKPLADLAVEAVQTGQVEFIPKMWEKTFFEWMHNIRDWCISRQLWWGHRIPAYHCKTCKHVEVSETPVTACPSCNSKDVEPDPDVLDTWFSSQLWPFSTMGWPEQTPDLKKYYPTSVLVTGFDIIFFWVSRMIMMGMKFLKAPPFHKVLIHGLVRDKDGKKFSKSVGNVIDPLVMMEKYGTDSFRFFLAATLPEGKDILFDESRLGGYRSFCNKIWNSSRFILMNLEESFVPTGITSEIEKDLEPMDQWILSRFNRCLEEYNKAHSRFHFYEMAAAIYEFIWGDFCDWYIELVKPRAYGKVSPRSTEVAKQVLSDVLIRALGLLHPFMPFLTEEVHSVFSNQYIVTTPFPEAYPISYDAAGVQKLNLLQEIVTKIRVMRSENGVTPDKKCKAIVKSEDDITRLTISENEVSLLQLARLESIRIEATYEIQKTDSVSHFTKGEIILPLEGLIDIEKEKARLNKELQKSEVEKEKLEAKLSNPGFLSKAAPDVVEKEREKLKIFTDKVEVLKKGIQNLAS
>CP026671.1|AXX14671.1|617185_618466_-|phosphoribosylamine--glycine-ligase
MQVKLKVLLIGSGGRESAIAFHLRKSSLLSELKVFPGNGGFPDNEILPSDSFNILSKESVQSFLKLNPFDFIVVGPEDPLVAGFADWAAELEIPTFGPDSYCAQIEGSKNFAKSLMVEANIPTAGYKTFTEYSASLNYLESQTVPIVIKADGLAAGKGVTVATTKKMAMNALKEIFEDKKFGESGNQVVIEEFMEGQEASIFAVSDGDSYFLLPAAQDHKRAFDGDQGPNTGGMGAYCPAPVITETILQKVKEKIFDRMFETFRKKGHPYRGLLYAGLMISPDGEPKVVEFNCRFGDPETQCVLAMFDGDLLELLYIASTGKIKEVRTSIKSGAATVVVLAAQGYPDSYEKNIPLNLPETSGQNVYLFHAGTSKKDGKVFSSGGRILGVVAQGTDLRNSVDQAYSFLEKIQVPKTFYRKDIGHKAL
>CP026671.1|AXX14680.1|631637_632855_-|aspartate-kinase
MPNIIVQKYGGTSVGTPERIQNVARRIKSYHDKGQQIAVVVSAMGHTTDDLVELAAKISANPPKREMDMLLSTGEQISTALLAMALWEIGVPATSFTGSQIKLLTDGNFSNAKIKMIDRSRIDTALNEGKVAIIAGFQGIDEEENITTLGRGGSDTSAVAVAAVLGAKECEIYTDVDGVYTADPRIVPNAKKHTQITYEEMLELASLGAGVLHSRSVELGMNYDVVIHVRSSFNENQGTLVMSEDKIMEKLKVSGVTAKSDQARITIAEVPDKPGLAARLFGELNSKHILVDMIVQSSPHNGINTISFTISKKDVLQAKPILQGFSKTHNAKEPEINESIAIVSAVGVGMKSHVGVAAGMFQALADNGINIEMISTSEIKISCVIPEDQAKIAINKIHDVFGLSG
>CP026671.1|AXX14681.1|633033_634848_+|sodium-transporter
MFSVLDWFFILLYLLFAFAAGILLSPKAGKSLVSYFVADRKLPWWWLGTSMVATTFAADTPLVITGFVAADGISANWFWWSWAIGYMAMTVFFAGKWRKMEVLTDVEFVELRYGGKPATILRMVKAFYLSILVNSIVLGWVFKAMSKITGPFLDWTDILGVDGFAIVRNLWPSFLIFDSLNNTITVLILFLIVVVYSSMGGIQGVILTDLVQFALGMGGAILFAVYAVSSQGGISGLLMGMKEIYPDKHESILSFWPDFQGASLPFNVFLIFISVQWWAQYYSDGSGYLAQRIHTAKSPEEAEKGSLWFNVANFIVRTWPWILTALVTLVVFPLHDPTRYFSEGQIVGGDREMGYPILMKLILPSGVLGIVFASLMAAFMSTADTHINWGASYLVNDFYLRFLHPGADDKTLVRVSRIAVVLMAIVAVLVATQIQSIASAWKFLLAFASGMGLPQILRWIWWRTNAWTELSGMITALTLSMILYPFFPEVRSEYLLFWVAIGSVVVSILVTLTTPPVPKDTLDAFVKRADPFGFWKGQGSKKRLEDFQEKIVLWILGTVSLFFGMFSLGCFFLLKFWQGACCLIGFVAFGFFYWKKEFGNNGVD
>CP026671.1|AXX14682.1|635484_636105_-|hypothetical-protein
MDFMNAFFKFSQKQFRVLSSYKNNPVKLLSFLLFIQFFAVCDSGRNSEKKEILLRLISEFQIDLQKNLESAIRTKGIVGAINVCRTISPKKEADLKAEFPGVLIRRVSEKPRNPSHRSEIWETEIFNQWKESQKAGMAPYTIVLSKDKEVRILQPIILQNATCLQCHGGPQDINPAVSKKIAELYPNDQAKGYKLGELRGAFSATW
>CP026671.1|AXX14683.1|636310_637060_+|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MSGHSKWATIKRKKDAIDSKRGAIFTRVGKEITVAAKMGGGDPEGNPRLRLAILKAKSVNMPKDNIERAIKKGTGELEGVVYEECLYECFGPAGIAIMVSAVTDKKSRTTPEIKSILTKLGGSLATSGSVSRLFEKKGVIVLESSQIGEDKLVDIAVGGGAEDVINEGEVYRVITTPDDYESVLHALNEKGLKSEESEIRYIALVSSEIADKEVAEKVMKLIEQLDGHDDVTSVMSNFELAASLEKEFE
>CP026671.1|AXX17118.1|637138_637660_+|endonuclease
MRSGIFNLRIIGIDPGSHRAGYAVLEKTASKIRILAYGTVEVPSGTPSPNNLLVLRKGLTEILKEFKPSIASVEEMFFAKNKKTASRVFESRGVLLVTLAEMNIQILEPTVSQIKKGTTGSGTADKKQIRQALKLLLDIDLLKGHDDSWDAVAAAYVGLSMSSSPLFAARFKV
>CP026671.1|AXX14684.1|637820_638738_-|alpha/beta-hydrolase
MNDYLTYVSDNRSVRNPILQFLAEKWYTILCIWHMIIGMFIELENSPEGDKRPVVLVPGFLGRTLSWEPMLKHLSANGHPVYVVPLGFQVGNIRTKSKILENFLIEKGIKDCYIVGHSMGGLIASGLTYKGRDRVKKIFIAGTPVRGTYLSYFLPMFICSWQMMPNSKFIREVGEVFGKLPNVQSVFTKKDQVILPSENSRLGHFDDVELPEAGHMNLFMGPLGIECLFDLITAEEKKDPKPIIRKVESTKQPEDVEFSKTPSKSPAPASKKKPAPKKNSSPLKPAKSKSIPKKKSAPVKKKKKR
>CP026671.1|AXX14685.1|638935_639436_-|peptide-methionine-(R)-S-oxide-reductase
MKNMFLFPVILVSLVFSGCCKVGGDSNRTNQKGESMSYEINKSEDEWKKELTPEQYKILRQKGTEMAFTGALYKNQDKGTYVCAACGAVLFSSETKYESGSGWPSFYQPTKEGAVNEEKDNTHGMVRTEILCAKCGGHLGHVFNDGPSPTGLRYCINSASLKFRKE
>CP026671.1|AXX14686.1|639702_641511_-|WGR-domain-containing-protein
MKKYLIYQDEGSKKFWSIQVSGSTFTVTFGKIGSSGQSSTKTFSDEKECLKEAEKLFREKLKKGYVEAELTEQRSETELPEQNSEPIQKLLSDSFHQFLKVKVKDFEESKYAKTFQKINWEKEAEKVFQSVCSYWKKLKEKNIEPIGIFDIRWDDAATQYSIEFDYDTESNDPKNAMEEGAVDNESVIDFSDLIRKNLKEEPDDIWETMGEDYTVMQNILCKMSKEIILQTLKENSFLQIEKQTPYYLIFAYYHDDEESEVIFDSSGKIKNSPYPELTKKGIDLSKLYNSKDKSMLIEDRNLEEIPDEIGDYQDLETLSCWNTKIAKLPNTITALQNLKDLSIISKKLTEFPIEICKLSNLRYLYIRTEKINKLPEDVGALVNLNHLNLCGNKLKDLPKNLQKLTLLKRLNLGENKFEKIPTALYGMNSIEELDLRHNPFKSLDGIGKITGLITIHTYAVGIKELTPEIGQLKNCKYFHLSDVDIEEIPKEIGDMDSMYTLEISKTKIRFLPDTIGKLKNCKSLDIQKNQIEFLPETIGTMENLEELSAGNNKLTDLPESIYQLKKLKEIGLWGNSFSQDQKAKIVSRLKENIPGIKINIDK
>CP026671.1|AXX14687.1|641775_642390_-|TetR/AcrR-family-transcriptional-regulator
MKTRPNKKKESGTGVRERILDTVTSLFYKQGFSNTGMRQIIQESNSVAASLYDHYPSKKELGLAYLSRQEEKTLSDLQDLMDRYPDLGEFLRAWVILKEKQIRHGEFVGCPFAGFASQVMDSDPEYTEFLKDIVTKWTRIISDYLQKAIGSGQLKRNMDIQYVARRILMAYHGSVTMWRMTRELRFIREMDNSLREIVEEYRIF
>CP026671.1|AXX17119.1|642621_643482_+|acyl-[acyl-carrier-protein]-thioesterase
MIANEIQLVTRISDLDTQRHVTSRTYENFCLEGRFRTLEENGFSLREILSQEIAIHPLESQIRFLAQQMEGTNLKTETKAFPLGSGKIFWDQKVLSDVETLAAEIKTLTFSEKGGKSIDLLPLEKTEMSGFDQFPQIPDFRGTCKTVDTEMVTLYSERNIFGEYNPAYFWRIIEDSRWFFSTETGLTLNRFVEMDTTMFFMGGVFKFFHPVPAGRRIKVSTWIHSFEKIRSYMRHEVTDAETGLRYFAVQDEQLVVSFSKVRPKKAPEEFQRLVGEYVEHFEYSKI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP026671_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026671_2

1088257-1088727

TypeI-E

I-E,II-B

Consensus_repeat	Method
CGGTTCAACCCCACGCATGTGGGGAATAG	CRISPRCasFinder
CGGTTCAACCCCACGCATGTGGGGAATAG	CRT
CGGTTCAACCCCACGCATGTGGGGAATAG	PILER-CR

7 spacers

cas2,cas1,cas6e,cas7,cse2gr11,cas8e

The CRISPR arrays of CP026671_2

>merge|CP026671|2|1088257-1088727|CRISPRCasFinder,CRT,PILER-CR
GGGTTCAACCCCACGCATGTGGGGAAAAGGAAATCAGGTGATCTTGAAGTGAGTGGAATTTCGTATAACGATAACGGTTCAACCCCACGCATGTGGGGAAAAGCGCAACACTCGCCGGTTCCCATCTCGCACAAAACGGTTCAACCCCACGCATGTGGGGAATAGTTAATCTATCCGAGTTCGAAAGCATCGAGCGTCGGTTCAACCCCACGCATGTGGGGAATAGTGTTCGAAGATTTTTGTTCAAAGAACCAAATGCGGTTCAACCCCACGCATGTGGGGAATAGCAGGACGAATGCGTTCTCGTTTCTGCGACTGACGGTTCAACCCCACGCATGTGGGGAATAGTATGGCATCACTATAAAGGCCGTACAGGATAGGCGGTTCAACCCCACGCATGTGGGGAATAGTAAGTCACTTTCCAGGATCATCCAAATGTCTCCGGTTCAACCCCACGCATGTGGGGAATAG

>CP026671|2|2|1088257-1088727|CRISPRCasFinder
GGGTTCAACCCCACGCATGTGGGGAAAAG	GAAATCAGGTGATCTTGAAGTGAGTGGAATTTCGTATAACGATAA
CGGTTCAACCCCACGCATGTGGGGAAAAG	CGCAACACTCGCCGGTTCCCATCTCGCACAAAA
CGGTTCAACCCCACGCATGTGGGGAATAG	TTAATCTATCCGAGTTCGAAAGCATCGAGCGT
CGGTTCAACCCCACGCATGTGGGGAATAG	TGTTCGAAGATTTTTGTTCAAAGAACCAAATG
CGGTTCAACCCCACGCATGTGGGGAATAG	CAGGACGAATGCGTTCTCGTTTCTGCGACTGA
CGGTTCAACCCCACGCATGTGGGGAATAG	TATGGCATCACTATAAAGGCCGTACAGGATAGG
CGGTTCAACCCCACGCATGTGGGGAATAG	TAAGTCACTTTCCAGGATCATCCAAATGTCTC
CGGTTCAACCCCACGCATGTGGGGAATAG

>CP026671|2|1|1088257-1088727|CRT
GGGTTCAACCCCACGCATGTGGGGAAAAG	GAAATCAGGTGATCTTGAAGTGAGTGGAATTTCGTATAACGATAA
CGGTTCAACCCCACGCATGTGGGGAAAAG	CGCAACACTCGCCGGTTCCCATCTCGCACAAAA
CGGTTCAACCCCACGCATGTGGGGAATAG	TTAATCTATCCGAGTTCGAAAGCATCGAGCGT
CGGTTCAACCCCACGCATGTGGGGAATAG	TGTTCGAAGATTTTTGTTCAAAGAACCAAATG
CGGTTCAACCCCACGCATGTGGGGAATAG	CAGGACGAATGCGTTCTCGTTTCTGCGACTGA
CGGTTCAACCCCACGCATGTGGGGAATAG	TATGGCATCACTATAAAGGCCGTACAGGATAGG
CGGTTCAACCCCACGCATGTGGGGAATAG	TAAGTCACTTTCCAGGATCATCCAAATGTCTC
CGGTTCAACCCCACGCATGTGGGGAATAG

>CP026671|2|1|1088331-1088727|PILER-CR
CGGTTCAACCCCACGCATGTGGGGAAAAG	CGCAACACTCGCCGGTTCCCATCTCGCACAAAACGG
TTCAACCCCACGCATGTGGGGAATAGTTA	ATCTATCCGAGTTCGAAAGCATCGAGCGTCGG
TTCAACCCCACGCATGTGGGGAATAGTGT	TCGAAGATTTTTGTTCAAAGAACCAAATGCGG
TTCAACCCCACGCATGTGGGGAATAGCAG	GACGAATGCGTTCTCGTTTCTGCGACTGACGG
TTCAACCCCACGCATGTGGGGAATAGTAT	GGCATCACTATAAAGGCCGTACAGGATAGGCGG
TTCAACCCCACGCATGTGGGGAATAGTAA	GTCACTTTCCAGGATCATCCAAATGTCTCCGG
TTCAACCCCACGCATGTGGGGAATAG

Protein	Signature genes	Signature genes Name	Protein_function
CP026671.1\|AXX15051.1\|1095202_1096804_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl\|CDD\|187860
CP026671.1\|AXX15036.1\|1083892_1085257_-\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
CP026671.1\|AXX15042.1\|1088768_1089188_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|378244
CP026671.1\|AXX17165.1\|1086742_1086937_-\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15048.1\|1091774_1092575_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09727_cas6e_CAS-I-E	gnl\|CDD\|215025
CP026671.1\|AXX15040.1\|1086398_1086719_+\|QacE-family-quaternary-ammonium-compound-efflux-SMR-transporter	unknown	unknown	gnl\|CDD\|224987
CP026671.1\|AXX15041.1\|1087009_1088161_+\|DUF5009-domain-containing-protein	unknown	unknown	gnl\|CDD\|226749
CP026671.1\|AXX15037.1\|1085338_1085581_+\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15033.1\|1078929_1079586_-\|thiol:disulfide-oxidoreductase	unknown	unknown	gnl\|CDD\|183298
CP026671.1\|AXX15043.1\|1089120_1090005_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
CP026671.1\|AXX15038.1\|1085954_1086134_+\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15044.1\|1090081_1090282_-\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15045.1\|1090508_1090853_+\|DUF962-domain-containing-protein	unknown	unknown	gnl\|CDD\|377609
CP026671.1\|AXX15049.1\|1093590_1094664_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
CP026671.1\|AXX15034.1\|1079684_1082858_-\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	unknown	unknown	gnl\|CDD\|226220
CP026671.1\|AXX15039.1\|1086184_1086376_-\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15050.1\|1094660_1095197_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
CP026671.1\|AXX15046.1\|1090935_1091481_+\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15035.1\|1082861_1083896_-\|efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
CP026671.1\|AXX15047.1\|1091500_1091758_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP026671.1\|AXX15036.1\|1083892_1085257_-\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	4.74451e-19
CP026671.1\|AXX15042.1\|1088768_1089188_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	7.16526e-34
CP026671.1\|AXX15040.1\|1086398_1086719_+\|QacE-family-quaternary-ammonium-compound-efflux-SMR-transporter	gnl\|CDD\|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	9.99826e-27
CP026671.1\|AXX15041.1\|1087009_1088161_+\|DUF5009-domain-containing-protein	gnl\|CDD\|226749	COG4299, COG4299, Uncharacterized protein conserved in bacteria [Function unknown].	3.35041e-54
CP026671.1\|AXX15033.1\|1078929_1079586_-\|thiol:disulfide-oxidoreductase	gnl\|CDD\|183298	PRK11752, PRK11752, putative S-transferase; Provisional.	1.48245e-71
CP026671.1\|AXX15043.1\|1089120_1090005_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.67276e-141
CP026671.1\|AXX15045.1\|1090508_1090853_+\|DUF962-domain-containing-protein	gnl\|CDD\|377609	pfam06127, DUF962, Protein of unknown function (DUF962). This family consists of several eukaryotic and prokaryotic proteins of unknown function. The yeast protein YGL010W has been found to be non-essential for cell growth.	4.23805e-40
CP026671.1\|AXX15049.1\|1093590_1094664_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	2.86739e-117
CP026671.1\|AXX15034.1\|1079684_1082858_-\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	gnl\|CDD\|226220	COG3696, COG3696, Putative silver efflux pump [Inorganic ion transport and metabolism].	0
CP026671.1\|AXX15050.1\|1094660_1095197_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	2.06433e-29
CP026671.1\|AXX15048.1\|1091774_1092575_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|215025	smart01101, CRISPR_assoc, This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	7.80562e-65
CP026671.1\|AXX15035.1\|1082861_1083896_-\|efflux-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	7.98079e-25
CP026671.1\|AXX15051.1\|1095202_1096804_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|187860	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	3.03418e-148

>CP026671.1|AXX15041.1|1087009_1088161_+|DUF5009-domain-containing-protein
MEKKSTQNKDRILSLDLFRGMTVVGMILVNNPGSWSYVYSPLKHAEWNGCTPTDLVFPFFLFAVGASIPISLYSKNGINRIRVWIGICIRGISLILLGLFLNFFGEWTFSELRIPGVLQRIGFVYWVVATLFLIFPGKKVLVFLIPILLVHTWILTHIAPPGESMVSLEQGKDIGAWIDRTIFGEKHLWKFSKTWDPEGFLSGIASIATSLFGVICGFILFRREGRGKNRVLSIFGLGFLFTFVGLLWDRSLPMNKSLWTGSYAVYTTGLSFLCIGFFEYLDSLILLKKWNGLDLKIFFQPFFVFGKNAILVFVGSGILARTLNFWTIVLENGKSVGVKVWFFSKLVLFADPYLASLLYAVLHLSVWWGILSFLDKRKIYIKV
>CP026671.1|AXX17165.1|1086742_1086937_-|hypothetical-protein
MISRDHFSPNPLFEFQKIYSSSQNPSSDHRSEALSLREFGSNSTTLQSPLYLLTHVILRFWNRL
>CP026671.1|AXX15040.1|1086398_1086719_+|QacE-family-quaternary-ammonium-compound-efflux-SMR-transporter
MAWIYLIIASTFEIGFTTCLKLSDNFTKPTWIGGFVVSAVFSLAFLNKAVQTIPMGTAYAIWTGLGAAGTILVGIVIHGEPIDFWRGFFLSTLILSVLGLKFLVSE
>CP026671.1|AXX15039.1|1086184_1086376_-|hypothetical-protein
MDINSLSKNPDHCRPRKKSDKLEFLSNRPINGNESVVLRIRIESVLWIPQSRQTPAFAQEIRL
>CP026671.1|AXX15038.1|1085954_1086134_+|hypothetical-protein
MGYLSALLKGYFFSRKFQSQESYPRKIIIRTLDGTEFVVFAIFSWGFPKLEDMFRIDFL
>CP026671.1|AXX15037.1|1085338_1085581_+|hypothetical-protein
MIRKYESFLLNPIWRTENVFDSVVLDLIESSGQNRERSLYFPSKEREGGNFSFLIGNAPSFAQTFFGSAFSEGKGTDEKR
>CP026671.1|AXX15036.1|1083892_1085257_-|TolC-family-protein
MYGSTKCFFFIHIIQFIIIFFFSFEILSKNDGDSLAFFEEYLSKEKFDSPKRIKIDLKKAEETFLRNNLSLLAKRLEIEASKAEIIQTHLWDNPILSIDQNIYNQNTNRYLDTTRNGQTTIQIEQIFVLAGKRDKRIRIAQWNTNTKEQDFYDLLRALKLELRVTFYKLSFLKKSLEFFDENINSIRKTIKSSEAVYKNRDILLSEVLRLKSILFRLETDRSEIVSDIIEKENILKLLLNEPNYSEAILEIETTDLDEKRNSILAKSDQELLSIAFEKRPDLKALEFGIKAEQTNLALQRSLAIPDLTLGGSWDRAGNYINNYYGFTVSISIPTFDRNQGNIRESELILASKKAKYEEKKIKIKAEVLSAVGKAKEKERLLLEYKNSFTKDYQNLASLMVENYRKKYLTILEFSDFFEAYSDSFLKMLRLQSDRIGSLESVNYTLGSTVLEIGR
>CP026671.1|AXX15035.1|1082861_1083896_-|efflux-transporter-periplasmic-adaptor-subunit
MILKNIFSSLILFYQTRLKSILFVGFLILTLAIFLHNRNLSKKTQEHRKLEKATSPQVTEAGAKIEFPKDYPGLARLVYQKIRKGNADFSVMASARVIASINTSVNSGEKLILFDSGETTHLYSEYKRTRVVASKAFKDLTRVRDMYVNQAATRRDVTEAESNFAVAKAEGAEAESKLRTIGFNPKELDSVSGTSYWIICDVPESQLSEVENGEEVKIQFPSFPGKIFLGKAEAIGEVIDPVLRTVKVRVTLKNTKEKILPGMFARVDFGDPRSSILAIPNRAIVTVDEKNYVFLKENEHSFRRKQVVLGSSGEERTIIKEGLSEGDEIVIDGAFLLKGISFGF
>CP026671.1|AXX15034.1|1079684_1082858_-|CusA/CzcA-family-heavy-metal-efflux-RND-transporter
MVERLIEFSLKRRIPTILLALFVFGIGLWSWNTLKKEAYPDVGDTQVTVIALLPGKAALEVEKQVTLPLERELNTVPYVLTRRSKTIFGLSVLQLIFEDGVSDFTARELVLEKIRNADLPQHANLSLAPLTGPVGEIFRYTIEAGEEWSGMDLRTIQDWIVIPALRQVNGVADVINFGGLVKQYHIITSPNRIYRYNLSIRDVIETISSNNRNTGGHTLTRGDQSFAVRGLGAIQNTDDIRNTVIASSGGTPIYIGNLASVEEYPKQPDGIFSYALKDPHSSNIKLRESGVQGLIAMRRGENPSEVVERVKEKLEEINRNYLPKGVRLTTTYDRSDLVNFTVNTISRTLFEGISVVVLVLIFFIGSVRSALVVACTIPLSLLFAFSLMKVTNIPANLLSLGAIDFGIIVDGAVVVVDNISRKYKEAKGKKISGLSFKEIETLTIEGTKEVGIEIFFSISIIILAYMPIFTFQRIEGKLFSPMAFTLSYAISGSMLIALTFIPVLMTFLYRSKLEKNGNDSLEWQNPIFIKIQNFYSLFLAKRLVDPKKVVAFTWILVLGIGSFSYFRLGIEFLPELDEGSINIRCFFPVGISLKTSEKYVPIIRSTILKHEQVSSVLTQLGRNDEGSDPYGPNRLEILVGLKDYSVWKEKISKRQLLSKIKKELQENLPGIGFLFSQPILDNVTESVTGSVSDLAILINGEDLNILRNLGEQILTTISEIPGATESGIEQEGDQTQLTIEINRKQAARYGINTSEILDTMEAAIGGKKVGMLYDDFKRFEIVVRYTNDFRSSIDSVRTLLVTGPGGARIPLSELANINFKDGPTIIQRQDGKRQISVRTNIRGRDQGSFAAEAKELVAEKIKIPEGIEIHWGGQFENLHRAVSRLRFVIPLTLFAIFLILYVMFKTPQMVLLAMSGIPISISGGLLALLFRGTNFSVSAGVGLISLFGISTMTGVLFISRLLHMLEKNQNKDLKSSVIEAAVIQLRPRIMTVLLALLGLIPAAIASGIGSDIQKPLATVIVGGLTLELLVTLVYIPSLFYLTEKRKRIVPNSSNKNG
>CP026671.1|AXX15033.1|1078929_1079586_-|thiol:disulfide-oxidoreductase
MIELYSASTPNGRKVSIMLEELGIPYTIHPIDLDKLEQKQEWFLKINPNGRIPAIIDTDNGNFAVFESGAILIYLAEKTGKFLPKDPKEKSIALQWLMFQMGGVGPMQGQAGVFLKYAPEKIPFAISRYQNETKRLYSVLDRRLGESQFLAGKELSIADIATWPWVNIHDWVEISLDEFPNLKRWNEELAERPAFIKGKNIPNKTNHKNNTEEIKKKA
>CP026671.1|AXX15042.1|1088768_1089188_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MVVLILERVKTSQRGEMSRLAIELKPGVFVASINARVRDRIWKKISEEWKSDAIMLFSSNSEQGYGIRSHGDPSREIMDFDGLLLMSKPDPKRDQIEVMNDSDFSITTEDEVSPFSDLKGFFNEKANRLLLEADVPDES
>CP026671.1|AXX15043.1|1089120_1090005_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MPNRNLQELPKFEDNWSHLYFEKGRIDQFQKSIGFHYLDKVVPIPIETIGLLLLGPGTSITHEAIKRISDSRCLLAWTGEGGVRFYSAGYTGTYSARNLLRQVEAYGNPKERVSVIRKMYQFRFSDEIPADATIEQIRGLEGARVRKIYREWSENSGVPWKSRSYDQNSWDWSDPINRALSSANACLYGVVHAAILQSGFSPAIGFVHTGKQLSFVYDIADLYKAEITIPLAFEITAEDATNVERRVRFACRDKFKHSKLLKRIIPDIKELIYGGFDFGESEDFSEGRDVAVSH
>CP026671.1|AXX15044.1|1090081_1090282_-|hypothetical-protein
MQKSSVSNRLVCPYKIECPECLLQSLIQCKIYEPYRMIQTNLFQFSKKPTRKKIRQIAIAHYILNL
>CP026671.1|AXX15045.1|1090508_1090853_+|DUF962-domain-containing-protein
MTTEATPKTYATFKEFWPFYLGEHSHPVNRALHFIGTSFAIGWILAAIANFNPFYILTGLFFGYFFAWIGHFFVEKNRPATFTYPLKSFMGDWVMYFYILTGQIGKELEKIGKK
>CP026671.1|AXX15046.1|1090935_1091481_+|hypothetical-protein
MEKKFSFLLILLPVLFFTINSCSRVWNIGILNQKDNKVTLVLKLRIPVLQHHFQSWITGTEFHSGNLQLPFLDLRNWFRVKSGSITYWSNCWSNQSKFEEKIQLRNIRYNEDRGEVSLELSPKYAYFIDWSNNNNDPRSLIYSYSEIRVESSVGKIAYSGEEILNAFQYDEDCECFLMTLK
>CP026671.1|AXX15047.1|1091500_1091758_+|hypothetical-protein
MKKPTNFYTDLMRRRLKPVAIRVEEHKSIVCKIRGDSFVAIRHRLREIGRLLKKSTFASELTLLNTPIRVYESDTENKRTIFAKI
>CP026671.1|AXX15048.1|1091774_1092575_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MFLSQLKLDTHNTNNKIVFNWIQNPYNIHQRLWMAFSEYSSKDKPQNSPFLFQLDYNSDPGKISPRILVFSEKLPNWERAFQEFKVLTEIPVGNQIKQISPTFIQAGAVLRFSLTANPTKKLKDYRSLFQEELEGFPDKFDPSDRVSFLEGKSKLEDLKKTLTKDQIQKLKSKRVGIYHEKELLNWLSKKGNDNGFSLLNAVVEFQSDFSANKIKGSLSPSIPKIHTVSFSGILKIMDPALFKIAYTKGIGTGKAFGCGMLLLART
>CP026671.1|AXX15049.1|1093590_1094664_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MNRFIQFHFLTSYPPSNLNRDDLGRPKTAMLGGANRLRISSQSLKRAWRTSDLFRETLSGHIGTRTKEKGKEIYQKLLDGKIPEKNARTWSKSIAGRFGKLKNPSEKELEKNPLLDLEIQQLTHFSKEENEAISSLIQKLIDSKKEPSNEDLNLLKKENSSSDIAMFGRMLASDPAFNIEAAVQVAHAITVHKVAIEEDFFTAVDDLNSGIEDVGAGHLGEVEFGSGLFYLYICVNREQLLNNLNGNKDLAKRTIKALVETSSTISPTGKQNSFASRARALYCMAEKGNEQPRSLHTAFLNSVEDRGILNAAILKLESSRQNFEKVYGSCASGGFKTFNVDSGNGSLKEILEFAQED
>CP026671.1|AXX15050.1|1094660_1095197_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MKFYENKEKYKETIINWWIDLKSRTGDRAALRRCSNGLDTLLIPYTHRLISQLFQEGFQFFPDKIGPIAGILSHIEEDNPSVSFARSMARKEGENPVINEIRFRKILQYSDILSEELFYQNMVRIVKNLKKKANISDLSLSIYSWNQRTKKDWAYDYYGTPISENNLENSENLQGENQ
>CP026671.1|AXX15051.1|1095202_1096804_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNLIKDVWIPVQRFSEKLEEISPFEITSRIENDSDPIMSLNAPRPDFNGALLQFLVGLLQAVFPPENETEWEDLFVNPPSPEVLKEAMEKVKSAFELFGDGPRFMQDTNLNEEDTVFDISALFIESPGENTIKLKKDFFIKRNSISQICEKCAGIGLFSFQTNSPSGGQGHLTSIRGGGPLTTFVTSKLKNPKKNSLWSKLWLNVLPKSYFQVNGQKKIPFQSVFPWTNPKIEDLQSKGKTTTPKDLHPLSVYWSYPRRILLRKDVENGICDVCNRSSSVLVRSYHTKTYGLSYSEGGWIHPLSPYYKSKESWFPYHPQPGGILYHYWQTIALGKEQEDQAALVIRRFLNRKIPGEQTSILTFGYDMDNMKARCWYESEIPFFNIPSDKIEKFEEQVSQILNASTEVKKNLRQAVRNAWLDKKNDSKGDLTFLDVSFLKDTENSFYDLIRNVQENLISGVADFAALKETWLKLLNESACKLFDQYAESGSFEFENIERIVKARKNLKISNLGSKTRIILGLIVSEKTSKRNKK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP026671_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026671_3

1423560-1424015

Orphan

I-E,II-B

Consensus_repeat	Method
CGGTTCAACCCCACGCATGTGGGGAAAAG	PILER-CR
CGGTTCAACCCCACGCATGTGGGGAAAAG	CRISPRCasFinder
CGGTTCAACCCCACGCATGTGGGGAAAAG	CRT

7 spacers

csa3

The CRISPR arrays of CP026671_3

>merge|CP026671|3|1423560-1424015|PILER-CR,CRISPRCasFinder,CRT
CGGTTCAACCCCACGCATGTGGGGAAAAGGCGTCCGTAAAGACTCGACTCACGCCAAATCTCGGTTCAACCCCACGCATGTGGGGAAAAGAAATTGATGATGGTACTTGATGTTAAGTTTCTCGGTTCAACCCCACGCATGTGGGGAAAAGTGCTTTAGGACCTACATTCTTTAATCACATTGCGGTTCAACCCCACGCATGTGGGGAAAAGGCAGAGATGCTCGTAAAGATACATTCAGACGACGGTTCAACCCCACGCATGTGGGGAAAAGCTTTCATCACAGATAATCCAACAAAATACGGACGGTTCAACCCCACGCATGTGGGGAAAAGCTTTCATCACAGATAATCCAACAAAATACGGACGGTTCAACCCCACGCATGTGGGGAAAAGGAAGTTATTGGTTCTTTTTGTGCCTTCGGTCTCGGTTCAACCCCACGCATGTGGGGAAAAG

>CP026671|3|2|1423560-1424015|PILER-CR
CGGTTCAACCCCACGCATGTGGGGAAAAG	GCGTCCGTAAAGACTCGACTCACGCCAAATCT
CGGTTCAACCCCACGCATGTGGGGAAAAG	AAATTGATGATGGTACTTGATGTTAAGTTTCT
CGGTTCAACCCCACGCATGTGGGGAAAAG	TGCTTTAGGACCTACATTCTTTAATCACATTG
CGGTTCAACCCCACGCATGTGGGGAAAAG	GCAGAGATGCTCGTAAAGATACATTCAGACGA
CGGTTCAACCCCACGCATGTGGGGAAAAG	CTTTCATCACAGATAATCCAACAAAATACGGA
CGGTTCAACCCCACGCATGTGGGGAAAAG	CTTTCATCACAGATAATCCAACAAAATACGGA
CGGTTCAACCCCACGCATGTGGGGAAAAG	GAAGTTATTGGTTCTTTTTGTGCCTTCGGTCT
CGGTTCAACCCCACGCATGTGGGGAAAAG

>CP026671|3|3|1423560-1424015|CRISPRCasFinder
CGGTTCAACCCCACGCATGTGGGGAAAAG	GCGTCCGTAAAGACTCGACTCACGCCAAATCT
CGGTTCAACCCCACGCATGTGGGGAAAAG	AAATTGATGATGGTACTTGATGTTAAGTTTCT
CGGTTCAACCCCACGCATGTGGGGAAAAG	TGCTTTAGGACCTACATTCTTTAATCACATTG
CGGTTCAACCCCACGCATGTGGGGAAAAG	GCAGAGATGCTCGTAAAGATACATTCAGACGA
CGGTTCAACCCCACGCATGTGGGGAAAAG	CTTTCATCACAGATAATCCAACAAAATACGGA
CGGTTCAACCCCACGCATGTGGGGAAAAG	CTTTCATCACAGATAATCCAACAAAATACGGA
CGGTTCAACCCCACGCATGTGGGGAAAAG	GAAGTTATTGGTTCTTTTTGTGCCTTCGGTCT
CGGTTCAACCCCACGCATGTGGGGAAAAG

>CP026671|3|2|1423560-1424015|CRT
CGGTTCAACCCCACGCATGTGGGGAAAAG	GCGTCCGTAAAGACTCGACTCACGCCAAATCT
CGGTTCAACCCCACGCATGTGGGGAAAAG	AAATTGATGATGGTACTTGATGTTAAGTTTCT
CGGTTCAACCCCACGCATGTGGGGAAAAG	TGCTTTAGGACCTACATTCTTTAATCACATTG
CGGTTCAACCCCACGCATGTGGGGAAAAG	GCAGAGATGCTCGTAAAGATACATTCAGACGA
CGGTTCAACCCCACGCATGTGGGGAAAAG	CTTTCATCACAGATAATCCAACAAAATACGGA
CGGTTCAACCCCACGCATGTGGGGAAAAG	CTTTCATCACAGATAATCCAACAAAATACGGA
CGGTTCAACCCCACGCATGTGGGGAAAAG	GAAGTTATTGGTTCTTTTTGTGCCTTCGGTCT
CGGTTCAACCCCACGCATGTGGGGAAAAG

Protein	Signature genes	Signature genes Name	Protein_function
CP026671.1\|AXX15312.1\|1431219_1432101_-\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15307.1\|1421997_1422204_+\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15309.1\|1426548_1427295_-\|sphingomyelinase-C	unknown	unknown	unknown
CP026671.1\|AXX15300.1\|1415164_1416232_+\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15298.1\|1411313_1413338_+\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|223394
CP026671.1\|AXX15301.1\|1416962_1417142_+\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15308.1\|1424703_1425240_-\|sphingomyelinase-C	unknown	unknown	unknown
CP026671.1\|AXX15316.1\|1438493_1439579_+\|CARDB-domain-protein	unknown	unknown	gnl\|CDD\|369473
CP026671.1\|AXX15303.1\|1418382_1419162_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|187576
CP026671.1\|AXX15310.1\|1429596_1429857_-\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX17191.1\|1428257_1429484_+\|tetracycline-resistance-MFS-efflux-pump	unknown	unknown	gnl\|CDD\|340946
CP026671.1\|AXX15315.1\|1437100_1438036_-\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15313.1\|1432598_1434419_+\|translational-GTPase-TypA	unknown	unknown	gnl\|CDD\|224138
CP026671.1\|AXX15299.1\|1413351_1415154_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173862
CP026671.1\|AXX15311.1\|1430210_1431068_+\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
CP026671.1\|AXX15306.1\|1420752_1421247_+\|ATPase	unknown	unknown	gnl\|CDD\|176910
CP026671.1\|AXX15305.1\|1420362_1420701_-\|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
CP026671.1\|AXX15302.1\|1417080_1418382_+\|adenylosuccinate-lyase	unknown	unknown	gnl\|CDD\|176464
CP026671.1\|AXX15314.1\|1435272_1436487_+\|acyltransferase	unknown	unknown	gnl\|CDD\|224748
CP026671.1\|AXX15304.1\|1419458_1420265_+\|fatty-acid-hydroxylase-family-protein	unknown	unknown	gnl\|CDD\|377224

Protein	Function_ID	Function_description	E-value
CP026671.1\|AXX15298.1\|1411313_1413338_+\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	gnl\|CDD\|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
CP026671.1\|AXX15316.1\|1438493_1439579_+\|CARDB-domain-protein	gnl\|CDD\|369473	pfam07705, CARDB, CARDB. Cell adhesion related domain found in bacteria.	0.0094058
CP026671.1\|AXX15303.1\|1418382_1419162_+\|hypothetical-protein	gnl\|CDD\|187576	cd05266, SDR_a4, atypical (a) SDRs, subgroup 4. Atypical SDRs in this subgroup are poorly defined, one member is identified as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is related to, but is different from, the archetypical SDRs, GXGXXG. This subgroup also lacks most of the characteristic active site residues of the SDRs; however, the upstream Ser is present at the usual place, and some potential catalytic residues are present in place of the usual YXXXK active site motif. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.82339e-14
CP026671.1\|AXX17191.1\|1428257_1429484_+\|tetracycline-resistance-MFS-efflux-pump	gnl\|CDD\|340946	cd17388, MFS_TetA, Tetracycline resistance protein TetA and related proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of tetracycline resistance proteins similar to Escherichia coli TetA(A), TetA(B), and TetA(E), which are metal-tetracycline/H(+) antiporters that confer resistance to tetracycline by an active tetracycline efflux, which is an energy-dependent process that decreases the accumulation of the antibiotic in cells. TetA-like tetracycline resistance proteins belongs to the Eukaryotic Solute carrier 46 (SLC46)/Bacterial Tetracycline resistance (TetA) -like (SLC46/TetA-like) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.96179e-168
CP026671.1\|AXX15313.1\|1432598_1434419_+\|translational-GTPase-TypA	gnl\|CDD\|224138	COG1217, TypA, Predicted membrane GTPase involved in stress response [Signal transduction mechanisms].	0
CP026671.1\|AXX15299.1\|1413351_1415154_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173862	cd08497, PBP2_NikA_DppA_OppA_like_14, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	9.14447e-175
CP026671.1\|AXX15311.1\|1430210_1431068_+\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	4.92843e-70
CP026671.1\|AXX15306.1\|1420752_1421247_+\|ATPase	gnl\|CDD\|176910	cd08901, SRPBCC_CalC_Aha1-like_8, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins. SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of a functionally uncharacterized subgroup of CalC- and Aha1-like proteins. This group shows similarity to the SRPBCC domains of Micromonospora echinospora CalC (a protein which confers resistance to enediynes) and human Aha1 (one of several co-chaperones which regulate the dimeric chaperone Hsp90), and belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	1.48661e-49
CP026671.1\|AXX15305.1\|1420362_1420701_-\|ArsR-family-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.05572e-12
CP026671.1\|AXX15302.1\|1417080_1418382_+\|adenylosuccinate-lyase	gnl\|CDD\|176464	cd01360, Adenylsuccinate_lyase_1, Adenylsuccinate lyase (ASL)_subgroup 1. This subgroup contains bacterial and archeal proteins similar to ASL, a member of the Lyase class I family. Members of this family for the most part catalyze similar beta-elimination reactions in which a C-N or C-O bond is cleaved with the release of fumarate as one of the products. These proteins are active as tetramers. The four active sites of the homotetrameric enzyme are each formed by residues from three different subunits. ASL catalyzes two steps in the de novo purine biosynthesis: the conversion of 5-aminoimidazole-(N-succinylocarboxamide) ribotide (SAICAR) into 5-aminoimidazole-4-carboxamide ribotide (AICAR) and, the conversion of adenylsuccinate (SAMP) into adenosine monophosphate (AMP).	0
CP026671.1\|AXX15314.1\|1435272_1436487_+\|acyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	8.50897e-35
CP026671.1\|AXX15304.1\|1419458_1420265_+\|fatty-acid-hydroxylase-family-protein	gnl\|CDD\|377224	pfam04116, FA_hydroxylase, Fatty acid hydroxylase superfamily. This superfamily includes fatty acid and carotene hydroxylases and sterol desaturases. Beta-carotene hydroxylase is involved in zeaxanthin synthesis by hydroxylating beta-carotene, but the enzyme may be involved in other pathways. This family includes C-5 sterol desaturase and C-4 sterol methyl oxidase. Members of this family are involved in cholesterol biosynthesis and biosynthesis a plant cuticular wax. These enzymes contain two copies of a HXHH motif. Members of this family are integral membrane proteins.	5.96111e-29

>CP026671.1|AXX15307.1|1421997_1422204_+|hypothetical-protein
MFLRQLRAGLKTSKMWELPRKLDNNKTYSKADDRQRGENFSFYEKFKMNISVEVLRPALRTRIKTLGM
>CP026671.1|AXX15306.1|1420752_1421247_+|ATPase
MNLRFTVQTKIQKPLEAVFQAVYDPKHLSGYFTTGGASGPLVEGTKVIWKFADFPSMKGENEGVVVNVVEVVPDSKIVLEWDAHEGSYEGENELLTVGGYKTKTEMIFESLDPNNTLVKITESGWKVSQSALDGSYMNCQGWMNMSCCLKAYLEYGINLRKGFF
>CP026671.1|AXX15305.1|1420362_1420701_-|ArsR-family-transcriptional-regulator
MYKLDKQDLIFKALADSKRREILDLLRKKPKTTGEICSYFEPLDRCTVIQHLKILENAGLLIVKRKGRVRWNYLDNVPIQEIYDRWISKYAKPTLERLAVFKKQMDRDNRTK
>CP026671.1|AXX15304.1|1419458_1420265_+|fatty-acid-hydroxylase-family-protein
MGELLSRFGYSGFFGIIWGIFLIRYLVFSGIAFLVVWVFCGKKLSHKLIQSKKPEKEKIFYEIKYSMLTFFIFGLSGIFVVWAKVNGFNRIYNNVGDYGIVYLIFSSFVLVLLHDTYFYWTHRMMHHKLFFKYFHLVHHKSINPSPWAAFSFHPLEAIVESGIVPLVSFVLPLHPGAMIVFFVYMTSLNVLGHLSYEFFPSWFLKSRFTSWHNTTTHHNMHHKYFNCNYSLYFNFWDRIMGTNHEKYKEKFEEVASRVPEKAKLILGK
>CP026671.1|AXX15303.1|1418382_1419162_+|hypothetical-protein
MRVGIFGLGYTGIRIAKRLKLQAEVRLETFSAKTRVEGTEVFDFSNPFALKEFGEKFSREDFDLCVVTFPVQKLFDPISFINLLFSVGKRCILLGTTSIYKRVPDIVESTPLIEDHDRFAIENEWIGRSGKILRLCGIYGPLRNPGDWARKGLVKKCSKQLNLIHGDDVALTISLLIRKIRTTGWDTLPNVLNLSDNQWHTWKEIFSFLEEHEKISKTQVEESPKEDSFVDSGLIRSLLPDLQTKNFCMELEGLEGIGD
>CP026671.1|AXX15302.1|1417080_1418382_+|adenylosuccinate-lyase
MIDRYSNPEISKIWELENKFEIWKEIEILACEIRMKRGEIPPEEFQEIKTMAKFNVGEILEIESKVHHDVIAFLTNMNSYIGPAGRHVHYGLTSSDIGDTALCVQMVQAMDLILKKTDALISVVKEKAIQYRDLPCIGRSHGIHAEPMTLGLKFALFFEELNRNRKRMSEARNEIAVGKLSGAVGTYSNVDPEIEAYVCEKMGLKVDPISTQVVSRDRHAFYLSVLGVTASSLDRMATEIRLLQKTEGREVEEPFSAGQKGSSAMPHKRNPVICERISGLSRVIRANVNVGLQDVALWHERDISHSSAERVVLPDSTIALEYILDKMLFVVKNLHVYPDAIERTLGVTRGLIFSQKVLLALIERGKIAREEAYLIVQEHAMAVWANPSETLKTRLENDNRVSQVLTRKDLEDIFKIEPYLEKVGLIYRRLGLE
>CP026671.1|AXX15301.1|1416962_1417142_+|hypothetical-protein
MYKKTNDRVSNAFFTDFVFLFTEYTSVEEWMRIQKGTFRNDRSLFQSRNFQNLGIREQV
>CP026671.1|AXX15300.1|1415164_1416232_+|hypothetical-protein
MNKRNRFEELGGVIRDFLSSPKIPNFIEFLEKGLDKELFYDPEKTKPEIPIEDLPVDYRLRESGFARKTYERLFPVSHLFRITHRYEREYLDNFMPLSTGKYIGRGSYKFVYALPWNQVVKVGKSKLPSDPIFGSLYKHVQKNLDRYLKSEEIQLMEFLESKAWARSSKENIRFKFARLGLERLHYWKLKSLIPDLVLPTRYFMGLRARTTPFGVPIFTLTPCDNQNLLPGKHLKEFIRLNEKIRQNPLQDAFFPKWKLNFDTHKFGVVSRSRLKKIALDFHRVIEVTKHLAEEEKLIFDIHSENIIITFPDFSLKIFDYHVFDEHLYEPSKENPSPEIDHINTIREFVRSFELG
>CP026671.1|AXX15299.1|1413351_1415154_+|ABC-transporter-substrate-binding-protein
MKRYSIFCMFFVLSVFTFLACGDKEEFETSAVVETLPWNGNPNSIPVALRGQNPIVSPHAKKGGTFRIYSHQFPKSLNYYLDQFSTTAHIFSLMFEPLLDYHPITLEPIPHLASSWRVSPDKKKFTFTIDANAVWSDGKPVTANDVLFTYETLMNKNNNTAVFRIDLSRFEKPVVLSEREIEFTQKEIHWSNFNTIANSLYILPAHYYKDRNFDKENFDFPVVSGPYSMLSAKKGRYIKMRRRGDYWMRAYPFYKGLDNFDTILFKVYNEESIAFQAFKKGDIDIYPTYTASFWVKDAIGEKFDENYILKQKIYNSKPIGFQGLVFNMRREIFSDVKVRKAFAHLVDRKLLIEKLAYNEYEETNAFYQDLWPANSFPNPPLEFDVTKARELLAKAGWKINSKGILEKDGKEFRFSILERDKKSEKYLTLIQERAKEVGIIINLESTDLAEWSSRMDKYDFDMTWAAWGGGVFKDPEAMWYSKYAEEKGQPNLSGFKNVAVDKLIDQQRTEFNITKRNEILKKIDKILTAEVPYVLLWNTSATRVMYWNRFRAPKNPLGKFGSEREASSLWWFDEEQSSKLNDAILKKEKLSPVPGKVYFQ
>CP026671.1|AXX15298.1|1411313_1413338_+|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase
MGFVKTPATKDMLLEGVRETLGESAYESVQKAYDVSERAHQGQFRLSGEPYIVHPLQVGFILYELGLDEKVICAGLLHDVIEDTQYSRDDMIRDFGEDITDLVEGVTKISKIKSQSKETEAAENIRKIIVATIKDIRVILIKLADKTHNMRTLSFQLPEKQKRIAQETLSLYAPIAGRLGIYKIKSELEDLAFQVLNPEEYQEVKKNINSKKSEREGFIETLKIILLQRLSEIQIEADVDGRAKHFYSIYRKMKLKEKTFNEIFDLRAIRIITNEVKDCYGVLGIVHTLWNPVPGRFKDYIATPKTNMYQSLHTTVIGPDGKPLEVQIRTRDMNDIAEYGIAAHWMYKEGKPSLSEKNVKVRWLELLSSWQDSALDPKEFVEELKYDLHEDEVFVFTPKGEILQLPKGATILDFAFRIHTDVGLKAKGGRINGRMLPLRTELRSGDQIEIITDKRTKPSPIWLRIVRTPSARQKLRSYFRKLKEENKKDLQQEAEFAAEITLNVEVLEELKKKPLAKPAKQIDLGAGKVIVAGLRGIPARLSGCCSPLPGDGIIGFVTRGRGVSIHKKGCATAKQQEQEESMRIITVEWDYGQSESIPVLIEVKSKDRQGIFMEIVKSISNTQTNIRESKASTDQRGNLVANFEVDVEHLDQLKEILSNLKQIPDVYQAHRIKN
>CP026671.1|AXX15308.1|1424703_1425240_-|sphingomyelinase-C
MRKAKPRPRPKRKYDGVTFVSYATGKRIQANSKAPKGWLKVDASRDTYFTRFNLYQDGGDPNCIKSGRIRVETSANPKYYWNWWLRGGGGNYAYYPKYNDGSKRLGILVLSGGCLESGGKVAFEDHDIITNTHDYYITVWKGGSWNEYLFLWGKTINPGPREIFTAILSPTPPEAAAE
>CP026671.1|AXX15309.1|1426548_1427295_-|sphingomyelinase-C
MKMIQKIFRKEKKKKQNKFKISKFFGGYCVLLLLFFFNCLPDQQSHEDNLLLSLLSLPNDQSLELQQDRSMRKAKPRPRPKRKYDGVTFVSYATGKRIQANSKAPKGWLKVDASRDTYFTRFNLYQDGSDPNCIESGRIRVETSANPKYYWNWWAGGGGGNYAYYPKYNDGSNRLSILVMSGGCLESGGKVAFADHDTLGYGYDYYITNWKGGSWNEYLFLWVRTLNPGPREIFTAILSPTPPEAAAE
>CP026671.1|AXX17191.1|1428257_1429484_+|tetracycline-resistance-MFS-efflux-pump
MVEFMNPQRPAALGFIFVTVLIDVIGFGIIVPVLPKLIQELTHGSLSDVAWYGGLLMFAYSFVQFISAPFVGGLSDRYGRRPILLASLFGFTLDYLFLAFAPSIFWLFVGRVVSGIMGASFTTGYAYIADISPPEKRAQNFGILGAAFGLGFIIGPVIGGSLGQFGSRAPFLAAAALTLVNWLFGFFVLPESLTDENRRKFEWKKANPIGSLINLKRYPMIVGLIVAFFLMNTAAHAVQGTWNYYTMEKFQWNEAMIGYSLGVVGLVYAVTQGGLIRIILPVLGQNRSIYLGLALSALGYALFALATQSWMMFVFLIPYCLGGIAMPPLQGIMSSQVPPREQGELQGALTSLMSVTAIVGPILMTGLFSYFTARETPIYSPEAPLWMGTILTAASLWISVGSLRKHHS
>CP026671.1|AXX15310.1|1429596_1429857_-|hypothetical-protein
MLLGHTKIVPEINGRFLQRCRSSHKIASNYRPFLKKIYVLIFETNLSRSQNLRNVGAITILNDGRKPPMRRFLWELSRFLKTCRIV
>CP026671.1|AXX15311.1|1430210_1431068_+|pirin-family-protein
MKIISAVIKELGDNFRVRRILPSIEARHVGPFVFVDHMGPVPIQTGKELTVRSHPHIGLATITYLYDGVILHRDSIGSEMPIRPYEVNWMTAGSGIAHSERSQLDSQYSILEGIQTWVALPKESEEVSAEFFHLDQKDIPVIKGESWELRLIAGEFLGKRSPVKVYSSLFYADLDVEPGAKGEWNIPGDQESALYVARGSLEIRDQKIQVGQMAVFNSGETISFSSTQGGRSILLGGIPFPERRYLWWNFVSTSPERIEKAKLEWKEERFPKVPGETERIPLPEG
>CP026671.1|AXX15312.1|1431219_1432101_-|hypothetical-protein
MLHFIFYFLILISLIACNESKNKINSDLLLLLAISTPDRAENYDRDVQIITNLSTFTDSGKVEITCDLNYSSQQDIDYYVEQLKKEIARYPRGYWIKADVDKIVLCKSMTTADGRIKLAFSDINLLAISVTQPMATMRYGTTTCGGIPNFNSFECYDQPAIHHELTHSVDRSLTPAINFLLYFDPEWEKLNAPGFQYYGSENFLQIPVVWHPLPGIMGRYGASHFVEDRAVFGALIMGWPATYNILVQACQTDPFVAAKVRLTVSRWKQFWPFPGAENTEWKIRMAQAERDCD
>CP026671.1|AXX15313.1|1432598_1434419_+|translational-GTPase-TypA
MEIRNIAIIAHVDHGKTTLLDGILRQTGAVTAKEDGERIMDSNDLEKEKGITIKAKNTAVVYKGTRINVVDTPGHADFGGEVERVLATADSCLLLVDAFDGPMPQTRFVLGKSLQLGHKPILVINKIDRPGARPEAVVDMAFDLFSDLGATDEQLDFPIVYASAKQGWAVYNLSDSPGTNLDPLLDTVLKHVPPVQADTEAPLQFQVTSLDYNDYVGRIAVGKIYAGKMALGMNVIQLAAKKSDTTTPTDTALFRITKLYNFEGLKRNEVNNAEAGDIVAIAGLPDVFIGDTICEPGKPAPRPAIEVEEPTVSMFFMVNNSPFAGKEGKFVTTRNIRERLDRELETNVAMRLEETEDKDRFKVLGRGELHLSVLIETMRREGFEIQVSRPEVILKTNEQGQKLEPYEYLVMDIPDQFTGTIIAELNRRKGELQLMDAHPSGMTRVEFVIPTRGIIGFRGFFISETRGEGVMSSRFLRFDIYKGEIPGRKNGALISMDSGETTAYALWKIQERGELVIGPNTAVYPGMIIGIHSRENDLEVNPVKEKKLSNVRSSGADEAIRLVPPRKFSLEQNIEFLDDDELLEVTPANLRLRKKFLDATMRKRNK
>CP026671.1|AXX15314.1|1435272_1436487_+|acyltransferase
MKTFIKDLWFHRDNEIQSLNGLRAFAIILVILNHYALAWKKIGTLQSDSLFWSGVDLSFVLSGFLISKGLLSDWTRNGAINFQKFYLKRTFRIFPAYYFFITFSLVASSFVLKIAEKKGLEQEAYVLSFKLSNAWGDFVFLGNYFPGMNIHTWSLSIEEQFYLVFPLFCNLLLFKMNPKHRQPLLWSLLLIPTTFRVIVYMTTDIPLTPEYFNEIYFPFHTRFDSLVMGVIAMDLYVGHKNLVSRLKADNRLYYPLLFVFFSFLFVAHWVNLRTDSFFTHTFKYNLLNIGFAGILLFAVVRSEGFLSRFLSLKLFVPVARLSFTIYLWHLILIGISLSILKIRTEPSSTLVLFSQFIFVLVLVVILSIPFYALIEYPFQYLKTKILLKKRSSEKSLQVQSESPI
>CP026671.1|AXX15315.1|1437100_1438036_-|hypothetical-protein
MRIKIEYIIILLYIILFIGCGKNLRGKPTPPNPDLAGFYLSSETAEWTKDGKMKIEVLSIFPKSNGDLSFERKTIVRLSFITSDNREEWRIRTGGVVTSENEILLQESLYQEFHQPHMGTRESDPKRWKLSEMGAASKVREVGNVTLSGNLLGEISPDNKTLRFSKMTFTKIGGSFQGRITTHVNQKSVTIDNETAGVVFYKAAVNTAEQIVSVFSKSELIKPGMIFLVGKDQVPCKIVEIHQHSGILEPVENGKILSVSVGDPVILKGDIDTKAINKRATADELIRKLKSDPNVSKEELIREIEKLKNVR
>CP026671.1|AXX15316.1|1438493_1439579_+|CARDB-domain-protein
MKEFLRKIITGMSVILIFYVTWNCGGEKQVDPSSLLMLLNSEQFSGTSAYSFEVMDLQNTDVNQVGPEFEISESDNSSKPDLMVYVYFGGSRQVKPGEDISRKISLQVANFGSVLAVGNRSGSEGYMIDLILSKDKVVPEGYASYTFDFQEDVLLGGGRISNTPNLVPGALVSVSEGSNIIPKNVPSGDYFVCARVDVGSKVSESDENNNTNCFPISIGFEEPLPDLIIPRASIYPSGMKCKAHKPMMYITAEIKNIGQGASPAMPDVGLINALDPSGIYGNGTGISMIQPGETVTVTFPIYFPVNASSDIDISLVEKTHTLDLRLNRGSWIPESNVQNNGYTRKPLELTIPEGYCKNHSR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP026671_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026671_5

1940304-1940397

Orphan

Consensus_repeat	Method
AAACTCAACGCAGAGCTTTCCTGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026671_5

>merge|CP026671|5|1940304-1940397|CRISPRCasFinder
AAACTCAACGCAGAGCTTTCCTGAACTCAATGCATCGCTTCCTACGGGTCGCTCTGCAGGTCGCTCTGAAAAACTCAACGCAGAGCTTTCCTAT

>CP026671|5|5|1940304-1940397|CRISPRCasFinder
AAACTCAACGCAGAGCTTTCCTGA	ACTCAATGCATCGCTTCCTACGGGTCGCTCTGCAGGTCGCTCTGAA
AAACTCAACGCAGAGCTTTCCTAT

Protein	Signature genes	Signature genes Name	Protein_function
CP026671.1\|AXX15734.1\|1950273_1951800_+\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|240355
CP026671.1\|AXX15722.1\|1935722_1936460_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|180838
CP026671.1\|AXX15719.1\|1931566_1932700_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133022
CP026671.1\|AXX15731.1\|1944875_1946867_-\|ligase	unknown	unknown	gnl\|CDD\|377422
CP026671.1\|AXX15729.1\|1940815_1942474_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369446
CP026671.1\|AXX15735.1\|1951801_1952584_+\|outer-membrane-lipoprotein-sorting-protein	unknown	unknown	gnl\|CDD\|319986
CP026671.1\|AXX15725.1\|1937955_1938345_+\|ribonuclease-HI	unknown	unknown	gnl\|CDD\|260011
CP026671.1\|AXX15736.1\|1952593_1953283_+\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|367950
CP026671.1\|AXX15721.1\|1934196_1935693_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
CP026671.1\|AXX15727.1\|1938704_1940003_+\|[cytidine(C)-cytidine(C)-adenosine-(A)]-adding-enzyme	unknown	unknown	gnl\|CDD\|237339
CP026671.1\|AXX15733.1\|1949039_1950203_-\|DUF1577-domain-containing-protein	unknown	unknown	gnl\|CDD\|369443
CP026671.1\|AXX17227.1\|1942981_1943176_-\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15724.1\|1937641_1937959_+\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15723.1\|1936751_1937519_-\|arginyltransferase	unknown	unknown	gnl\|CDD\|234939
CP026671.1\|AXX15720.1\|1932718_1934188_-\|dolichyl-phosphate-mannose--protein-mannosyltransferase	unknown	unknown	gnl\|CDD\|227621
CP026671.1\|AXX17228.1\|1946977_1948678_-\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15730.1\|1943237_1944869_-\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15732.1\|1948768_1948948_+\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15726.1\|1938364_1938712_+\|hypothetical-protein	unknown	unknown	unknown
CP026671.1\|AXX15718.1\|1930034_1930343_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045

Protein	Function_ID	Function_description	E-value
CP026671.1\|AXX15734.1\|1950273_1951800_+\|IMP-dehydrogenase	gnl\|CDD\|240355	PTZ00314, PTZ00314, inosine-5'-monophosphate dehydrogenase; Provisional.	0
CP026671.1\|AXX15722.1\|1935722_1936460_-\|SDR-family-oxidoreductase	gnl\|CDD\|180838	PRK07102, PRK07102, SDR family oxidoreductase.	8.45532e-63
CP026671.1\|AXX15731.1\|1944875_1946867_-\|ligase	gnl\|CDD\|377422	pfam04932, Wzy_C, O-Antigen ligase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. This family includes O-antigen ligases such as E. coli RfaL.	8.34009e-07
CP026671.1\|AXX15729.1\|1940815_1942474_+\|hypothetical-protein	gnl\|CDD\|369446	pfam07642, BBP2, Putative beta-barrel porin-2, OmpL-like. bbp2. BBP2 is a family of putative porin proteins that are likely to be outer membrane beta barrel proteins porins.	4.19705e-41
CP026671.1\|AXX15735.1\|1951801_1952584_+\|outer-membrane-lipoprotein-sorting-protein	gnl\|CDD\|319986	cd16329, LolA_like, proteins similar to periplasmic molecular chaperone LolA, the outer membrane lipoprotein receptor LolB and the periplasmic protein RseB. This family contains uncharacterized proteins similar to the periplasmic molecular chaperone LolA, the outer membrane lipoprotein receptor LolB and the periplasmic protein RseB, all of which have similar unclosed beta-barrel structures that resemble a baseball glove-like scaffold consisting of an 11-stranded antiparallel sheet. There are five Lol proteins (LolA, LolB, LolC, LolD, and LolE) involved in the sorting and membrane localization of lipoprotein and are highly conserved in Gram-negative bacteria. LolA accepts outer membrane (OM)-specific lipoproteins that are released from the inner membrane by the LolCDE complex and transfers them to the OM receptor LolB. It is proposed that the LolA/LolB complex forms a tunnel-like structure, where the hydrophobic insides of LolA and LolB are connected, which enables lipoproteins to transfer from LolA to LolB. RseB exerts a crucial role in modulating the stability of RseA, the transmembrane anti-sigma-factor that is degraded during sigma-E-dependent transcription caused by bacterial envelope stress. Its structural similarity to LolA and LolB suggests that RseA may act as a sensor of periplasmic stress with a dual functionality, detecting mislocalized lipoproteins as well as propagating the signal to induce the sigma-E-response.	6.14766e-12
CP026671.1\|AXX15725.1\|1937955_1938345_+\|ribonuclease-HI	gnl\|CDD\|260011	cd09279, RNase_HI_like, RNAse HI family that includes archaeal, some bacterial as well as plant RNase HI. Ribonuclease H (RNase H) is classified into two evolutionarily unrelated families, type 1 (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type 2 (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. RNase H is involved in DNA replication, repair and transcription. RNase H is widely present in various organisms, including bacteria, archaea and eukaryotes and most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site (DEDD) residues and have the same catalytic mechanism and functions in cells. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. Most archaeal genomes contain only type 2 RNase H (RNase HII); however, a few contain RNase HI as well. Although archaeal RNase HI sequences conserve the DEDD active-site motif, they lack other common features important for catalytic function, such as the basic protrusion region. Archaeal RNase HI homologs are more closely related to retroviral RNase HI than bacterial and eukaryotic type I RNase H in enzymatic properties.	1.61942e-53
CP026671.1\|AXX15721.1\|1934196_1935693_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	2.54521e-45
CP026671.1\|AXX15727.1\|1938704_1940003_+\|[cytidine(C)-cytidine(C)-adenosine-(A)]-adding-enzyme	gnl\|CDD\|237339	PRK13299, PRK13299, tRNA CCA-pyrophosphorylase; Provisional.	2.12083e-86
CP026671.1\|AXX15733.1\|1949039_1950203_-\|DUF1577-domain-containing-protein	gnl\|CDD\|369443	pfam07614, DUF1577, Protein of unknown function (DUF1577). A family of hypothetical proteins in Leptospira interrogans.	3.41007e-92
CP026671.1\|AXX15719.1\|1931566_1932700_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|133022	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily. DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.	3.17174e-47
CP026671.1\|AXX15720.1\|1932718_1934188_-\|dolichyl-phosphate-mannose--protein-mannosyltransferase	gnl\|CDD\|227621	COG5305, COG5305, Predicted membrane protein [Function unknown].	4.35838e-12
CP026671.1\|AXX15736.1\|1952593_1953283_+\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|367950	pfam04452, Methyltrans_RNA, RNA methyltransferase. RNA methyltransferases modify nucleotides during ribosomal RNA maturation in a site-specific manner. The Escherichia coli member is specific for U1498 methylation.	3.67654e-51
CP026671.1\|AXX15718.1\|1930034_1930343_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.53843e-09
CP026671.1\|AXX15723.1\|1936751_1937519_-\|arginyltransferase	gnl\|CDD\|234939	PRK01305, PRK01305, arginyl-tRNA-protein transferase; Provisional.	1.48134e-86

>CP026671.1|AXX15727.1|1938704_1940003_+|[cytidine(C)-cytidine(C)-adenosine-(A)]-adding-enzyme
MTNVDPDELIKKIPENFREDIIRITQNIRKEGGECYLIGGSVRDLLLSKIPDEFDLTTSLLPDKILTLFKRTVPTGIKHGTVTVLIQDRSYEITTFRKDVDYIDGRRPEAVEFGVSLSEDLKRRDFTMNALALDLEAKRLIDEHSGLEDIQNKIIRTIGDPIERFTEDGLRPIRAIRFVSSLGFTLESETAKAIIQCRNITAKISKERVHDELNKTLKSKNPAPSLKLFKEFRILELFTNLKLYPTENTNVEKKIREVPVVPLSLRLSFLHAWLFGSFQDRNSAKQFMKDLRYSNQNTKDSLFFSDMLFMMLNRKDDVSLTDAEIRKAVLHPICVYAGRENLRILTEYILNLAYTYEPILKDIFDFRRILDLTERSQTLVVTELALRGEDILKACPNLPPKQIGSVLEKLLFHVLENPDENRKDFLFPLLFK
>CP026671.1|AXX15726.1|1938364_1938712_+|hypothetical-protein
MWRISFYVFLFYTASNCGRSLKDKLVVLQKEEKFEEMLLLCLSEKETQDTKELCRLAMEKTEAGIDRILSEKAELPYSQITVDPEWKKKIDIILENNRTLKNRYGNLWKKMIQND
>CP026671.1|AXX15725.1|1937955_1938345_+|ribonuclease-HI
MISIFCDGASKGNPGPSSIGVVAYKGDKEEFRISERIGETTNNVAEWTSLKKGLEECIRRKFDTIHAYMDSELVVKQVSGKYKVKHPNLLEYKKEVDKLVSSLQNFQITHVPREKNSVADKLANEAFQK
>CP026671.1|AXX15724.1|1937641_1937959_+|hypothetical-protein
MHNLFTNFEVKKRGLRVALFFTIVSLICFLTENTILQFIFLGLGFVSFVFTLVQPEIFYSFTNCSLEFVLVFLSGIVKVGLLLIYLIVFKPIRFMIGLFLGEKKS
>CP026671.1|AXX15723.1|1936751_1937519_-|arginyltransferase
MIRHKLQNFVNSLPISPERSCSYYPDRLSQIQYLPLQGKIEKDSLQFFFDSGFRRTGNILYRTSCNACRECLSYRVPLNQFVPSRNRKRLLKKNSDLVVRFGSPHLTVEKEILYLRYQRSRYQSFVIGESDQELLEGMRWNLFGYPENSLEMTLSLDEKILGFMILDSASDSLSAVYSVYDPDYPDRSLGSFAILYSILYAKELGMKYYHLGYFLPGHPDMDYKKYWVPSEIRELDTNDWIPFEEFQKKYADFSW
>CP026671.1|AXX15722.1|1935722_1936460_-|SDR-family-oxidoreductase
MAKKIVVGASSGIGKELAILLLEQGHTVTLVARRDKELKAIAAPFNSPGKTNAFVIKQDVTNFDQVDSAFQKAVKSMKGVDEIYYASGIMYDVKPDEFDVTKDIAMLNTNLLGCVAWLNPAAVLFQKQKSGKIIGISSIAGDRGRRGNPVYNTSKAGMNTYLEALRNRLSTLGVQVLTVKPGFIDTAMTRGMKGLFWLISAKEAATIIVKAADSGKECVYVPARWGLVGLIIRLIPSFLFKRLSI
>CP026671.1|AXX15721.1|1934196_1935693_-|FAD-binding-oxidoreductase
MARASKVSPKKKTSAKTSKTAKVKKSPIEITLPLPSKVETWGMNHYSLSPVFFPEKEEDFRDLFSYANNKGLKLTLRGGGCSYGDAATNTKGVVIDISRYNRILEFNSKTGIIKAESGVTIKQLWEFGIEKGYWPPVVSGTMFPTLGGALSMNIHGKNNFAVGSIGDHVLEFTFMTPNGKVFVCSRKKNQELFFAAISGFGMLGVFLNVTIQLKAIYAGKMKVWPVVSKNLQDMFDYFEREYKSADYLVGWIDAFASGNSLGRGQIHKAVHLKKGEDPDFPENCKLERQNLPSTFLGIIPKSWMWLFMIPFANNLGMRLVNFAKFVSGYLTNNKPYFQGHAEYAFLLDYVPNWKFMYKPGSMIQYQSFIPKENAVDAFCEILKICQKRRIVTWLAVFKKHKSDPFLLTHALDGYSMAMDFPVTFGNRKRLWELAGELDEIVLKFGGKFYFAKDSTLRPETVQRAFPKKNLEKFYSLKRKFDPKGILETDLYRRITGTW
>CP026671.1|AXX15720.1|1932718_1934188_-|dolichyl-phosphate-mannose--protein-mannosyltransferase
MNRLNALLIEIKKDKVFLFLLGLGAFFRFFRLDLQSPWEDELFSIRASSETSFGNLWDWMKNDPHPPLYQTLLYFWFQLFQPTVFVGRLFSAIVGILVPFSFYLLSPHNLSGRIKTSVVVFLSLSTGLIYYSQELRSYSLLVLFSTIQLAILLKSVYENRKEKNFRIYWSLLGISLLASYTHFFGFIWSASIFLGIFITKWIFTKKFPKVEFYFGILFGILFIPVLYLLFNSDKIGIASWIPEAGFTAFLVFFDLIFHSGILKKFIPGIVASLALLAGFVSIYFPKNQMKTLALEPDHKKFVILLGIVFLIFSVVLGILSLIQPLITARNLLVTAPALYFLITTGFSLFPIYKGKRLELILILISIVSLYYFTRFYYKPFKEQWRESSQYIISTIQDRPLEFTLLCSSHTYNMEYFLKTAKIQGIVPKIYTKKEANLFVQDPTRKDLVILETSWKYLNSEDLDSLFAQKIFDRKDQLFYGMRVITIRKR
>CP026671.1|AXX15719.1|1931566_1932700_-|glycosyltransferase-family-2-protein
MKKKNVTYVIPCLNEEKTLPLVLEKLARLKKELKQYNVEILVSDNGSEDKSISIAKKYGAKVVHCEERGYGAALNFGIKNASGEIVLFADADDTYDFLESPALLAEMEKGAEFVIGSRLDGSIHKGAMPFLHRYLGTPVINWIINLLYSKKGNRVKDANSGFRCFLKKKFLEWEIESTGMEFASEMLVKALRSGVKLSHVPISLYPDVEGRVPHLRTWRDGMRHLLQILIHSQQLFYYTGLILFWIGWAFTILGYFTGIVAIGPFHIFGIHSLTVFLLVATFGQTIWAIGLFLAARKTPELSFYSRLNLLSEDLLFWYSARMILFVILLFAFILFRWWKNSFQVLDLEKEILMISFLSVQILNLIGQTITAHLLKRT
>CP026671.1|AXX15718.1|1930034_1930343_-|XRE-family-transcriptional-regulator
MFKSLHSREAKIFCKNLIAARKNADLTQLEIAKRLGEPQSYISKIESGERRLDVIEFWRIYKILGKSFEFYFQFDEKPEGSEKKSKTLKAASGKRKKKRSKF
>CP026671.1|AXX15729.1|1940815_1942474_+|hypothetical-protein
MMRIKTINLIGPVLCFLVFSQVFAQAGKKSGADASVAPAPTSQMMEQEDKKWYDQVEFSGFADVYYMYNLNPKQGGDIDATRAFETSNKNFAVNAVALTIQKAAEKSSPWGFRIDLQNGQNNAFQEAPYSQSNGIYNYNMLKQAYLSLYFPVLKGMTLDAGKMATHIGYEVLESMSNPNYSIGAIFQNTIPFIHTGVRLTTQFTDKWAGTFYLYNSGGGTGYNSPAATTIAPLNVITDPTYSGNAAGKSYFVEGQTERKAIGTQIKGQLIEDRLSVTWNTLYSSDGAYARVDPSKAAMATELANISGDPNIGMYNVANPRRAKYNKDYWFMNHVILSITPSDRITIDLDYTWSEKSGALANNNLDQKRYNVDATGAEVFNKDTLFWGLNNKRDSKTTYKAYGIFAKFKINETWGVNVRFEYIDDKHNNGALTTFNPFMGPNAYISTYKKTTDLAIADTVATAFAADANLGSLGITKEQILEVMSDDYKNYSGVRNAGQYKTFTVTPVWNFTENLLIKLDLRRDWATGKQFVDQKGDKTDHQYGITLGAVAKF
>CP026671.1|AXX17227.1|1942981_1943176_-|hypothetical-protein
MAPPSGLEKRRLDANINHKTKKGIKSRSQNLKKNISRRSGKFLKNVKVPTETVVLKVFSRRLKL
>CP026671.1|AXX15730.1|1943237_1944869_-|hypothetical-protein
MFNRLIFSTYSRYFIYLFAVLFLIFNRFKLDDKVPFVSSDSEIKYYQTIMFFEKGFKAVAESECLYPGKIYDPEFRYFPFDYPWAFLKENENRKCIFQYPPLFALLNGIPAYFFGAKIITLLPLLYLFGCLLIFDKILSLFIDKTWVILIGTLVPFTLSFPALSSVEFSEVPLNNFLLLSFGYFLIRSLFADKITVQNKNLNSNFRIFSFISGFLAVTAFFLRTESAFPIFLFGFLAFFSQKTRNNLKEYLIFSVPGGVLSFGFIGVLNFFYSGHPMGIRFLVSSQDAMSQFSIGKQIVILEGYLLGDATKSGFLKASPYAILIFGIFSDLIRKKELSGGSILGLVGIGTLFSISFFSPYTAGVHHFGLRYLESGFIFLSAGILIFLYQRNIEFPNIGRILILLTFLSLYYNYKFTREGFKILFGSIAPYLQIQNEFQSKRIIVHKGQFTNYLIGFSYLNSLHFTVYTEKDAIQLEQTFKKNRVDSYSILEYEPEPPKDPNLPEKQFKEKIAVRFPDPNRYYRVKDQKKILNFSLRTYQLYKN
>CP026671.1|AXX15731.1|1944875_1946867_-|ligase
MSLLLNLKTVPLIVLTFSLALLFFFDPSNPSLSRDSVVFSFFVWFVSLGISFRKKKFRIHPLFLLACLLLIGLSTVNGINRAPVVYFSQKLNLKLLYVAALCLAIYLFLKNIHPIFLFVHTVAFACSPPLFSSIKSVPLLLFVAASLFYLSPKKIRLRKLYVVVSISFFVLLISSLLSYKSQAALLQLCLLFSGILIFFLVSSYPSRFIKKGLLLILSSNLLLNTINLFSAIHTIWPFDLLQPSLLLTYAGFPVSSIAVISAFSALVAFYTAYQYGRYSWFLIPGGLIAIYLTYFNHSRASLLAFGLATLCIFLFRWSKKKIFFRIFIPSFCLIVLLSVGSVFFFPQETVSQYFDPKTLLIRFSLWNFHFQSVLQNAPIFGIGLDADSLLAHLPGTHSQKIGYDDFYKFLHSFRSYPQAHNLYVETFTSLGILGSLFFLWIALYLSLLSYRMLVSKSKKISDIGIFISGVLVFVAVHEFFDYNLGEQHFFIPVTLALSLIRTRSSSTMKTFGQNSSFKAVYAISLILLGYLSFQLVWEQRLRNLIIISIQDEIELDNFLIYKEKKVSGNRKKFSHPIEEITSNQIWIRSEENLVLASLILRKSPGHSDLMESFLDRCVRKNPYSSVCWKEKVDVLRKKDPNLDIRKELEEGKKTDPFHIIFTE
>CP026671.1|AXX17228.1|1946977_1948678_-|hypothetical-protein
MKRIFYFIFMILLILFGIISAYRMRWISDDAFISLRYAKNFADGKGLVFNEGEFVEGYTNFLWTILFIPFHLSDHIDPVNASYFFGILSFLGTCIYLVLFRKEFSRTEFPFALSCFVLLHHNRVFATGGLETSLHGFLFLAASYYFTNSGAVTFCKMLPGIVFSSLSCLNRPDGLLFHLLVGIFLILKFFQEVRPNNARSILLKPSFGIFCITYLSPVFFYIWKLEYYGNLLPNTFYAKSGGNVNLLQGLVYLRSFLTMYYGMIPIVGFLFFSLFQTIRKYSFPTQKKKDFRWILFVLFPILYSGYYTWIGGDFMFSRFYLPILPIVFIWTEQEILSLRESLSKGKKNLNIIFYSIPILILLRWDIYKGLPLPVVSGIADENQIYKRESVEQIRNRILPWKKHFENSKVRVAFTGSECILIYYLNPILAIETEAGLTDPVIARMEFENRERVGHGKPAPLQYLRDRNVHLLLYSSGLPIKTEYDEFLTGDFSAPWRILMYSPSVMKELLKIPSFRAVDFESYLDAYKQEYKRLDPILRKKKFSEFDSYYFRSGEDKNRREWYLKNL
>CP026671.1|AXX15732.1|1948768_1948948_+|hypothetical-protein
MQLNDSIYKNIFENETGCLAPIREDYFLFSTDSVVKRDSIFGYKTPRRLRNQSGKIHSF
>CP026671.1|AXX15733.1|1949039_1950203_-|DUF1577-domain-containing-protein
METIQRKKREKETISDPTKKFHIISKFLVQTDIIARVPGSTIQIIKILQVSKDATKILIQTEIPNAFPLNSHITLTKLLAKYVELNCEVIDERPNNQLILSVSDISIASKERSLSRISPPEGAVWITNIRTSRTTIDANLFNIPTSVKVNFADYETKLKSKYDFLKIDVFGTIGDKLDLVKKTRKILFIPNTQKEESYAAYDQEGFIDYASELGDSEDIRKKIIEYANQKIKSELIVPVIYLSHEEQAIPIGFVHAQNRNREIDILEVMEIKTLTFEMVDRIRESNTILVKERFPIVNISTGGLKVKINHPDLNQDLTKRAGFTFDIFFKMQAPLTAFGLIRSITKDVEGNLYVGLSIEGNSSRPGERKKYIDNVNRLLAESGQIQP
>CP026671.1|AXX15734.1|1950273_1951800_+|IMP-dehydrogenase
MSNQTYRDSEYLDGLSGDELFSLQIGLTYRDFLVLPGFIDFHPSEVELETRLTRNIRLKRPFISSPMDTVTESQMAIAQALMGGIGIIHYNNTIEEQVALVEKVKRFENGFITDPVVLGPKNIIRDLDRIKEHKGFTGIPVTEDGTRNSKLIGIVTNRDIDFERNREITLDEVMTKNVITGKEGITLQDANDIIKKSKIGKLPIVDSDGKLVSLVSRSDLKKNKEFPDASKDEGKRLRCGAAVSTLLESRDRVAALYEAGVDVIIIDSAQGNSNYQIEMIQFIKKEFKNLDIVAGNVVTRAQAENLIRAGADGLRIGMGPGSICITQDTMAVGRAQATAVYQTAKHAAKYDVPVMADGGISNIGDIANSLAIGASTCMMGFMFAGTTEAPGEYFYENGIRLKKYRGMASIEAMKAGGDKRYFNEGQKVKVAQGVSGSVVDRGSILNFIPYLSQGLRLSFQDMGYKSIPEIHKALREGKLRFERRSESAQAQGSVHGLYSFSAPTMRAE
>CP026671.1|AXX15735.1|1951801_1952584_+|outer-membrane-lipoprotein-sorting-protein
MDRILAFMVGLFALTVLSKETNSQGSNVRIAQELVARLDQALVKSNQGLIKGNLILIRRSGETWSWDVNMFRKEEDTLYLFESRGRGLEYKILIKDEGELIYTFNVLSKKIFRKVDEEKYESHLATGFSFIDLSGASYQANYNPIVQSDLKIADQTFKRITLKPIIPYFYSKLILLLNLDSLKPTRLDFHDRDGVLFKTMNIKYGLIKVKQNQKTTKEEYASRLEMLDLNTGSISVLEYTEIDKEVKPDSSLFELANLNR
>CP026671.1|AXX15736.1|1952593_1953283_+|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MEEAILFRREFLCEPQFCLNKEEVSHLKALRIFSEDKNLRILNGIGSEWIYEVKGNSRQGILKKTEVHVKPESISAIATAIPKGNRLEWLLQKGTELGLSRFYFLNFEQSDRRDFNLSRAQKIVEEASIQSKRIFLPEVFVPVSLNEFLNLQENLNLSIYQFDPKGKSEPKPEFFQNSIWIVGPEGGFREKEIRLLREKNILGVKAGNAILKIETAGIFAASLFRYFND

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP026671_2	2.4\|1088483\|32\|CP026671\|CRISPRCasFinder,CRT	1088483-1088514	32	NZ_CP006727	Leptospira interrogans serovar Linhai str. 56609 plasmid lcp3, complete sequence	25414-25445	0	1.0
CP026671_2	2.10\|1088486\|32\|CP026671\|PILER-CR	1088486-1088517	32	NZ_CP006727	Leptospira interrogans serovar Linhai str. 56609 plasmid lcp3, complete sequence	25414-25445	0	1.0
CP026671_4	4.1\|1716963\|32\|CP026671\|CRISPRCasFinder	1716963-1716994	32	KJ608188	Enterococcus phage EFC-1, complete genome	23247-23278	7	0.781
CP026671_4	4.1\|1716963\|32\|CP026671\|CRISPRCasFinder	1716963-1716994	32	NC_028671	Enterococcus phage vB_EfaS_IME197, complete genome	5787-5818	7	0.781
CP026671_2	2.3\|1088422\|32\|CP026671\|CRISPRCasFinder,CRT	1088422-1088453	32	NZ_CP039909	Agrobacterium tumefaciens strain CFBP6624 plasmid pAtCFBP6624, complete sequence	310377-310408	8	0.75
CP026671_2	2.7\|1088667\|32\|CP026671\|CRISPRCasFinder,CRT	1088667-1088698	32	AP014353	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S39-C37, * SEQUENCING IN PROGRESS *	26422-26453	8	0.75
CP026671_2	2.9\|1088425\|32\|CP026671\|PILER-CR	1088425-1088456	32	NZ_CP039909	Agrobacterium tumefaciens strain CFBP6624 plasmid pAtCFBP6624, complete sequence	310377-310408	8	0.75
CP026671_2	2.13\|1088670\|32\|CP026671\|PILER-CR	1088670-1088701	32	AP014353	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S39-C37, * SEQUENCING IN PROGRESS *	26422-26453	8	0.75
CP026671_4	4.1\|1716963\|32\|CP026671\|CRISPRCasFinder	1716963-1716994	32	NC_042136	Vibrio phage VP4B, partial genome	151189-151220	9	0.719
CP026671_2	2.5\|1088544\|32\|CP026671\|CRISPRCasFinder,CRT	1088544-1088575	32	NZ_CP025980	Escherichia marmotae strain HT073016 plasmid pEM148, complete sequence	65585-65616	10	0.688
CP026671_2	2.11\|1088547\|32\|CP026671\|PILER-CR	1088547-1088578	32	NZ_CP025980	Escherichia marmotae strain HT073016 plasmid pEM148, complete sequence	65585-65616	10	0.688

1. spacer 2.4|1088483|32|CP026671|CRISPRCasFinder,CRT matches to NZ_CP006727 (Leptospira interrogans serovar Linhai str. 56609 plasmid lcp3, complete sequence) position: , mismatch: 0, identity: 1.0

tgttcgaagatttttgttcaaagaaccaaatg	CRISPR spacer
tgttcgaagatttttgttcaaagaaccaaatg	Protospacer
********************************

2. spacer 2.10|1088486|32|CP026671|PILER-CR matches to NZ_CP006727 (Leptospira interrogans serovar Linhai str. 56609 plasmid lcp3, complete sequence) position: , mismatch: 0, identity: 1.0

tgttcgaagatttttgttcaaagaaccaaatg	CRISPR spacer
tgttcgaagatttttgttcaaagaaccaaatg	Protospacer
********************************

3. spacer 4.1|1716963|32|CP026671|CRISPRCasFinder matches to KJ608188 (Enterococcus phage EFC-1, complete genome) position: , mismatch: 7, identity: 0.781

tgtttcgatgtaatcgaatttctttgctttgc	CRISPR spacer
ttctgcaaagtattcgaatttcttttctttgc	Protospacer
* .* *.* *** ************ ******

4. spacer 4.1|1716963|32|CP026671|CRISPRCasFinder matches to NC_028671 (Enterococcus phage vB_EfaS_IME197, complete genome) position: , mismatch: 7, identity: 0.781

tgtttcgatgtaatcgaatttctttgctttgc	CRISPR spacer
ttctgcaaagtattcgaatttcttttctttgc	Protospacer
* .* *.* *** ************ ******

5. spacer 2.3|1088422|32|CP026671|CRISPRCasFinder,CRT matches to NZ_CP039909 (Agrobacterium tumefaciens strain CFBP6624 plasmid pAtCFBP6624, complete sequence) position: , mismatch: 8, identity: 0.75

ttaatctatccgagttcgaaagcatcgagcgt-	CRISPR spacer
gcggtctgtccgagttcgaaagcctcg-gcatc	Protospacer
 ...***.*************** *** **.*

6. spacer 2.7|1088667|32|CP026671|CRISPRCasFinder,CRT matches to AP014353 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S39-C37, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.75

taagtcactttccaggatcatccaaatgtctc---	CRISPR spacer
aaagtcaatttccaggagcatcca---gtgccgaa	Protospacer
 ****** ********* ******   ** .*

7. spacer 2.9|1088425|32|CP026671|PILER-CR matches to NZ_CP039909 (Agrobacterium tumefaciens strain CFBP6624 plasmid pAtCFBP6624, complete sequence) position: , mismatch: 8, identity: 0.75

ttaatctatccgagttcgaaagcatcgagcgt-	CRISPR spacer
gcggtctgtccgagttcgaaagcctcg-gcatc	Protospacer
 ...***.*************** *** **.*

8. spacer 2.13|1088670|32|CP026671|PILER-CR matches to AP014353 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S39-C37, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.75

taagtcactttccaggatcatccaaatgtctc---	CRISPR spacer
aaagtcaatttccaggagcatcca---gtgccgaa	Protospacer
 ****** ********* ******   ** .*

9. spacer 4.1|1716963|32|CP026671|CRISPRCasFinder matches to NC_042136 (Vibrio phage VP4B, partial genome) position: , mismatch: 9, identity: 0.719

tgtttcgatgtaatcgaatttctttgctttgc	CRISPR spacer
taacacgatgtaatcgaacttcgttgctaaga	Protospacer
*. . *************.*** *****  *

10. spacer 2.5|1088544|32|CP026671|CRISPRCasFinder,CRT matches to NZ_CP025980 (Escherichia marmotae strain HT073016 plasmid pEM148, complete sequence) position: , mismatch: 10, identity: 0.688

caggacgaatgcgttctcgtttctgcgactga	CRISPR spacer
ggtaataaatgcgttcttgtttatgcgacttc	Protospacer
 . .*..**********.**** *******

11. spacer 2.11|1088547|32|CP026671|PILER-CR matches to NZ_CP025980 (Escherichia marmotae strain HT073016 plasmid pEM148, complete sequence) position: , mismatch: 10, identity: 0.688

caggacgaatgcgttctcgtttctgcgactga	CRISPR spacer
ggtaataaatgcgttcttgtttatgcgacttc	Protospacer
 . .*..**********.**** *******

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP026671

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection