CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP032099	Arcobacter skirrowii CCUG 10374 chromosome, complete genome	2 crisprs	cas4,PrimPol,RT,cas9,csx20,csx23,cas6,cas10,csm3gr7,csx10gr5,csx19,csx1,cas2,cas1,WYL,DEDDh,cas3	0	4	2	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP032099_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP032099_1

833189-833712

TypeIII

Consensus_repeat	Method
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	CRISPRCasFinder
ATTACAACATTGACCCGATTNNTAGGGGATTGAAAC	CRT
AAATTACAACATTGACCCGATTTATAGGGGATTGAAACTT	PILER-CR

7 spacers

cas2,cas1,csx1,csm3gr7,csx19,csx10gr5,cas10,WYL

The CRISPR arrays of CP032099_1

>merge|CP032099|1|833189-833712|CRISPRCasFinder,CRT,PILER-CR
ATTACAACATTGACCCGATTTATAGGGGATTGAAACATAGCTTTTTCGTTATTTATTACTATCATTTAAATTACAACATTGACCCGATTTATAGGGGATTGAAACGTATTCTCGACATTGGAATCCTCCTTGATTATAATTACAACATTGACCCGATTTATAGGGGATTGAAACTTTCCTCCCTTTTTGAATAGGGCACATTTTTAAATTACAACATTGACCCGATTTATAGGGGATTGAAACTTCACAACTTGACCACTTCTTCTAGCTAAATCAATTACAACATTGACCCGATTATTAGGGGATTGAAACAACTTGTCCTAAACCCCTTTTGGGTATGGTTAGCCTATTACAACATTGACCCGATTATTAGGGGATTGAAACTAGTATCTGCTACTCCACCTACAGGGCTTTCACATTACAACATTGACCCGATTATTAGGGGATTGAAACAATATTCTTTAAAGGCTCTACTGATAAGAACTTTATTACAACATTGACCCGATTATTTTTGCCTTTGGCAA

>CP032099|1|1|833189-833712|CRISPRCasFinder
ATTACAACATTGACCCGATTTATAGGGGATTGAAAC	ATAGCTTTTTCGTTATTTATTACTATCATTTAA
ATTACAACATTGACCCGATTTATAGGGGATTGAAAC	GTATTCTCGACATTGGAATCCTCCTTGATTATA
ATTACAACATTGACCCGATTTATAGGGGATTGAAAC	TTTCCTCCCTTTTTGAATAGGGCACATTTTTAA
ATTACAACATTGACCCGATTTATAGGGGATTGAAAC	TTCACAACTTGACCACTTCTTCTAGCTAAATCA
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	AACTTGTCCTAAACCCCTTTTGGGTATGGTTAGCCT
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	TAGTATCTGCTACTCCACCTACAGGGCTTTCAC
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	AATATTCTTTAAAGGCTCTACTGATAAGAACTTT
ATTACAACATTGACCCGATTATTTTTGCCTTTGGCAA

>CP032099|1|1|833189-833711|CRT
ATTACAACATTGACCCGATTTATAGGGGATTGAAAC	ATAGCTTTTTCGTTATTTATTACTATCATTTAA
ATTACAACATTGACCCGATTTATAGGGGATTGAAAC	GTATTCTCGACATTGGAATCCTCCTTGATTATA
ATTACAACATTGACCCGATTTATAGGGGATTGAAAC	TTTCCTCCCTTTTTGAATAGGGCACATTTTTAA
ATTACAACATTGACCCGATTTATAGGGGATTGAAAC	TTCACAACTTGACCACTTCTTCTAGCTAAATCA
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	AACTTGTCCTAAACCCCTTTTGGGTATGGTTAGCCT
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	TAGTATCTGCTACTCCACCTACAGGGCTTTCAC
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	AATATTCTTTAAAGGCTCTACTGATAAGAACTTT
ATTACAACATTGACCCGATTATTTTTGCCTTTGGCA

>CP032099|1|1|833256-833433|PILER-CR
AAATTACAACATTGACCCGATTTATAGGGGATTGAAACGT	ATTCTCGACATTGGAATCCTCCTTGATTA
TAATTACAACATTGACCCGATTTATAGGGGATTGAAACTT	TCCTCCCTTTTTGAATAGGGCACATTTTT
AAATTACAACATTGACCCGATTTATAGGGGATTGAAACTT

Protein	Signature genes	Signature genes Name	Protein_function
CP032099.1\|AXX84696.1\|828130_828544_+\|CRISPR/Cas-system-associated-RAMP-protein,-type-III	csx19	mkCas0122_csx19_CAS-III-D	gnl\|CDD\|275216
CP032099.1\|AXX84705.1\|836407_836809_+\|putative-membrane-protein	unknown	unknown	unknown
CP032099.1\|AXX84693.1\|824952_825468_+\|CRISPR/Cas-system-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|377130
CP032099.1\|AXX84697.1\|828540_830331_+\|CRISPR/Cas-system-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274902
CP032099.1\|AXX84700.1\|832110_832719_+\|CRISPR/Cas-system-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
CP032099.1\|AXX84709.1\|839209_840736_+\|radical-SAM-domain/B12-binding-domain-containing-protein-(DUF4080-domain)	unknown	unknown	gnl\|CDD\|223963
CP032099.1\|AXX84692.1\|823534_824956_+\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl\|CDD\|187810
CP032099.1\|AXX84707.1\|837832_838762_+\|paraslipin-family-protein,-SPFH-superfamily	unknown	unknown	gnl\|CDD\|223407
CP032099.1\|AXX84704.1\|835996_836284_+\|hypothetical-protein	unknown	unknown	unknown
CP032099.1\|AXX84708.1\|838754_839189_+\|putative-membrane-protein	unknown	unknown	gnl\|CDD\|224501
CP032099.1\|AXX84706.1\|836858_837782_+\|transcriptional-regulator,-YafY-family	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
CP032099.1\|AXX84701.1\|832705_832978_+\|CRISPR/Cas-system-associated-endoribonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
CP032099.1\|AXX84703.1\|835451_835973_+\|porin-family-protein	unknown	unknown	gnl\|CDD\|379226
CP032099.1\|AXX84694.1\|825470_826850_+\|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	gnl\|CDD\|224256
CP032099.1\|AXX84710.1\|840728_841430_+\|DUF481-domain-containing-protein	unknown	unknown	gnl\|CDD\|377313
CP032099.1\|AXX84699.1\|831830_832097_+\|Cas2-family-CRISPR/Cas-system-associated-protein	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256
CP032099.1\|AXX84695.1\|826851_828144_+\|CRISPR/Cas-system-associated-RAMP-protein-Cas7/Csm3,-type-III	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|377130
CP032099.1\|AXX84711.1\|841577_842369_+\|RhuM-family-protein	unknown	unknown	gnl\|CDD\|379118
CP032099.1\|AXX84698.1\|830341_831592_+\|CRISPR/Cas-system-associated-protein-Csx1,-type-III	csx1	pfam09455_csx1_CAS-III	gnl\|CDD\|187863
CP032099.1\|AXX84702.1\|835117_835342_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP032099.1\|AXX84706.1\|836858_837782_+\|transcriptional-regulator,-YafY-family	WYL	pfam13280_WYL_CAS-I:CAS-III	1.1e-23	78.9	0.3
CP032099.1\|AXX84701.1\|832705_832978_+\|CRISPR/Cas-system-associated-endoribonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	8.1e-20	65.7	3.4
CP032099.1\|AXX84694.1\|825470_826850_+\|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	7.8e-65	213.7	1.6
CP032099.1\|AXX84697.1\|828540_830331_+\|CRISPR/Cas-system-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	3.9e-101	334.6	25.7
CP032099.1\|AXX84693.1\|824952_825468_+\|CRISPR/Cas-system-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	1.5e-18	61.7	0.0
CP032099.1\|AXX84700.1\|832110_832719_+\|CRISPR/Cas-system-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	4.2e-44	145.5	1.2
CP032099.1\|AXX84699.1\|831830_832097_+\|Cas2-family-CRISPR/Cas-system-associated-protein	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.6e-11	37.4	0.7
CP032099.1\|AXX84692.1\|823534_824956_+\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	1.8e-79	262.4	7.3
CP032099.1\|AXX84696.1\|828130_828544_+\|CRISPR/Cas-system-associated-RAMP-protein,-type-III	csx19	mkCas0122_csx19_CAS-III-D	9.9e-36	118.0	6.5
CP032099.1\|AXX84698.1\|830341_831592_+\|CRISPR/Cas-system-associated-protein-Csx1,-type-III	csx1	pfam09455_csx1_CAS-III	3.5e-51	169.2	18.7
CP032099.1\|AXX84695.1\|826851_828144_+\|CRISPR/Cas-system-associated-RAMP-protein-Cas7/Csm3,-type-III	csm3gr7	cd09726_csm3gr7_CAS-III-D	7.1e-36	119.0	9.8

Protein	Function_ID	Function_description	E-value
CP032099.1\|AXX84696.1\|828130_828544_+\|CRISPR/Cas-system-associated-RAMP-protein,-type-III	gnl\|CDD\|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	1.56458e-24
CP032099.1\|AXX84693.1\|824952_825468_+\|CRISPR/Cas-system-associated-RAMP-protein	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	8.37768e-09
CP032099.1\|AXX84697.1\|828540_830331_+\|CRISPR/Cas-system-associated-RAMP-protein	gnl\|CDD\|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	1.09039e-92
CP032099.1\|AXX84700.1\|832110_832719_+\|CRISPR/Cas-system-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	8.56387e-43
CP032099.1\|AXX84709.1\|839209_840736_+\|radical-SAM-domain/B12-binding-domain-containing-protein-(DUF4080-domain)	gnl\|CDD\|223963	COG1032, COG1032, Fe-S oxidoreductase [Energy production and conversion].	7.01782e-27
CP032099.1\|AXX84692.1\|823534_824956_+\|hypothetical-protein	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	8.93321e-09
CP032099.1\|AXX84707.1\|837832_838762_+\|paraslipin-family-protein,-SPFH-superfamily	gnl\|CDD\|223407	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones].	6.77029e-52
CP032099.1\|AXX84708.1\|838754_839189_+\|putative-membrane-protein	gnl\|CDD\|224501	COG1585, COG1585, Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	1.28236e-10
CP032099.1\|AXX84706.1\|836858_837782_+\|transcriptional-regulator,-YafY-family	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	5.16111e-18
CP032099.1\|AXX84701.1\|832705_832978_+\|CRISPR/Cas-system-associated-endoribonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.28049e-14
CP032099.1\|AXX84698.1\|830341_831592_+\|CRISPR/Cas-system-associated-protein-Csx1,-type-III	gnl\|CDD\|187863	cd09732, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as TM1812 family.	1.38796e-39
CP032099.1\|AXX84694.1\|825470_826850_+\|hypothetical-protein	gnl\|CDD\|224256	COG1337, COG1337, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	0.00815818
CP032099.1\|AXX84710.1\|840728_841430_+\|DUF481-domain-containing-protein	gnl\|CDD\|377313	pfam04338, DUF481, Protein of unknown function, DUF481. This family includes several proteins of uncharacterized function.	1.5037e-53
CP032099.1\|AXX84699.1\|831830_832097_+\|Cas2-family-CRISPR/Cas-system-associated-protein	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	0.000923357
CP032099.1\|AXX84711.1\|841577_842369_+\|RhuM-family-protein	gnl\|CDD\|379118	pfam13310, Virulence_RhuM, Virulence protein RhuM family. There are currently no experimental data for members of this group or their homologs. However, these proteins are implicated in virulence/pathogenicity because RhuM is encoded in the SPI-3 pathogenicity island in Salmonella typhimurium.	2.33212e-65
CP032099.1\|AXX84703.1\|835451_835973_+\|porin-family-protein	gnl\|CDD\|379226	pfam13505, OMP_b-brl, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	1.93763e-10
CP032099.1\|AXX84695.1\|826851_828144_+\|CRISPR/Cas-system-associated-RAMP-protein-Cas7/Csm3,-type-III	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	8.3242e-16

>CP032099.1|AXX84701.1|832705_832978_+|CRISPR/Cas-system-associated-endoribonuclease-Cas2
MKLHDYIICYDISDKKRLVKISKLLEKTAARIQYSIYFYPKVAKECIDDLVEKLNKLINQEEDDIRIYKIDIKNSIHLKSGIDLQNPFVI
>CP032099.1|AXX84700.1|832110_832719_+|CRISPR/Cas-system-associated-endonuclease-Cas1
MIAKDILLDKVKLHKLHLEKYEIDLNIKLILKKIEKAQNIDELMGIEGSFAKTYFKEFFSLLPKNMHKNKRSKNPPQDPANAVLSLFYTLYYNIISIKLLTHGFEPSIGYLHTPFREHNALASDLMELFRADINEEVIQIFKENLLSLDDFTKKGGVYLKYEARSKIWKRFLELEARLKSKLDKEVANIRAKISKDILDEVA
>CP032099.1|AXX84699.1|831830_832097_+|Cas2-family-CRISPR/Cas-system-associated-protein
MKNYLVLYDIFNTKRAYKIRKYLYKHTTGGQKSALEIPLDEKLSDKLIFKLNSYTKDIDKINIVKIYKNPILLGKASQLNIISNGVIV
>CP032099.1|AXX84698.1|830341_831592_+|CRISPR/Cas-system-associated-protein-Csx1,-type-III
MAKILITLLGTGSKAKGDNTNNNYELADYIIDDKIYEKRAFISSAIAEHYEVDKIFTIGTKQSMWDNLCEFYNTNEEYHFEVLNLKEKELLDEDKLEGLSSAIDKKLQNSGSKCFIIENSESSEEIWQMFEKMLHILDDVDDKDELYFDITHLFRSVSVFSMIIAEFAQITRDIKISGMFYGLLKKGKPSVVVDLSLYFEFLAWTRAIKSLKDYGNASELLKLLESSNQSKEIVNSFKSFAYSLSISDMGELQNSIEILKGKIDKFVLSNNPIVRLISKDLLEFINRFGKIKKDELAKFQFELTKWYSQNNNHAMAYITLAEASVTAVCEANNLDVASMEDRKKAQNILFEYSKWSNDYPKELQKIGETYSKINNIRNNIAHKLSGNSKRSKSTPTNSVENLSNYINILESLLKTK
>CP032099.1|AXX84697.1|828540_830331_+|CRISPR/Cas-system-associated-RAMP-protein
MITAPYNFVPLNKEIFYPSWADDVSHDVPFKDGESGEIDITITAKSPIFIRNHSKDKEKPTDEFCHHINQNGAKEFYIPSSSIKGMVRNVLEILSFSKITINENYKDIFGVRDMSNQKELVGGANGCGFLIKKDDEFYIEDCGQILTISHTNLEEKFKNLKKLESAKEKYNKFGLLKELKFSTYKKIMDIRGRKIPKNMAKFDNNSSLFGKLVFTGNIGNKKHEFIFKTNGKILELDKKVFNNFSNVYFKDENSVDGQFWKQNFPKTLKIPVFYIKDKDSNKIKHIGLTQLFKIAYNKSIFEASKQNIKENKLDLAQTIFGYVSKEKALKGRVQFSHFKSTIQRYEKEVEQVLGTPNPTYYPNYIRQTNTNRDKVNKYITLMDSNAQISGWKRYPLHSSIKNPPLIKKKDGSINHDITTHFKPLSKDTVFKGKLRFHNLKKIEIGALLSAITFHGQSDKYMHNIGMAKSLGYGKIDIKLEPRNLKYTQNEYLKEFENEISKHIPNWRNSEQLKELFAMANRDINIDKNKNLVYQLLENPKPKYKDKNDFTGAKKDKDYLLPYSGIIPNNANKAKQEPNRGDNKMNGIRIVSKVNKK
>CP032099.1|AXX84696.1|828130_828544_+|CRISPR/Cas-system-associated-RAMP-protein,-type-III
MKTYEEIKNFYINLEGKFEGYFQMSDEKLNKVYQEKQTLPSWEDLHEDKNFILEACLFDGNRSITIRNIGNSFVLIDKNISDFKEENITKQSFITNGYKEVIISQIWEEKEDENCLNIKVLKPTIQLFSGFKKGETK
>CP032099.1|AXX84695.1|826851_828144_+|CRISPR/Cas-system-associated-RAMP-protein-Cas7/Csm3,-type-III
MEKYRHIAHIIIEARTALKIGSNSIDALQDSPIQKDWNGLPMILGTSLAGVLRKEFDKTKVNDVFGDEDSKKKESKGSRVIFSNALLLNEDKKVTETLLLEKSDFLKNFEILPIRDHNSMNDKGVTNKHGKFDEEIIYKGTRFKFSIELISNKDDKEEFKSILDELYKNSFRVGAGSSKGYGQIEVLEITYDTFDITSKEYIEFSSSLNKTLKEKYENKSIIDDKYIKYELKLTPDDFFMFGSGYGDEQVDMTPVVEKVIDYENKTLSEEKIVIPASSVKGAISHRTTYHYNLKKGNFIENGVKAQIVEDIFGAKKDKKIDGFKGNILISDLYLEKNDTKIFDHVSIDRFTGGAIEGALFQEKTVASCESFILEILLNKEKIKDEVAIEAFENALKDITTGMLSLGGATTKGHGVFGGIVLKMEKNYENL
>CP032099.1|AXX84694.1|825470_826850_+|hypothetical-protein
MKKIYYKLTFLSDIVLQGSSNTLGKVETLDYITGSSILGIVAKNYDKFENPIDIFHSKKVRFGEATLLSENKECYKAPLCFFAPKEDFDKQEVKNNHFIDYKNQEELDKQYKQIRTGYINSNLDYLNLDFTYTQKAAYDKKNRKSEDGKMYGYNSIQKGTSWIFSLKIDDTINQNDKKLLEDSLVGVRYLGKSKSSSYGKVKIEELKDYKLENIENPITTGVNYIYVKSSLALFDENGMSTFIPTKESLALENAKIVWEETQIKTKTFTPYNSIRECFDFSRNIIQRGSVIALKNISPKDIETLKKGIGAYLNEGYGEVLINPSFLLKEDKFCLNKKDIVYEKIENETSKIDDDLVAFLNNKSEISKKTLTLVEEVEKYIEENKNSFKGVSKSQWGQIRAYTQFHKESYREKIKDFISHGISEKQWKDAKEKLEKLLDEKSLEFIKLFSMTMPKKDLEK
>CP032099.1|AXX84693.1|824952_825468_+|CRISPR/Cas-system-associated-RAMP-protein
MRYKITFLDYWHLSSGLSSGAKADSTVLKDKDGLPYFSGKTIKGLTREMAELTMDEKFINICFGNEGNSAGACYFSDVILDDSTRKIIVDKSLQSNLYTELASTKIDENGIAKTGSLREIEVVIPITLYGTIENIPKEYQTSMINALKSIKRAGLNRNRGLGRCKIEIVGE
>CP032099.1|AXX84692.1|823534_824956_+|hypothetical-protein
MSEYLYGASLQGLQEFIFKTNKLKEIIGASEIIKNFDKLELKKEFDLKEDATIILQAAGNLRVIFKNKEDLEKVVLKLPQYMMLKAYGVTISQAVVEYKNYKDSSQELEKLLKIQRNKSNISLDTHFNIIQQNPRTALPLIDSENDKATAQKIVEFKKFAKEIKKDDKDSIFDISYLSNKKNKIAIIHIDGNGLGNIVKDLTEADIKMFSKKLDDATNEAFKECVEKVFKSEDSKLKKRDVILGGDDVTLICDANQALDFTKYFLELFEEKTKNIYTNKEKNISYDLTACAGVVFCNEKYPFHYAVKLAEDLCSFTKKDSKKYAKEKKLNLAPSSLMFHNIQSSNVESFSKFIEDELTINGIRCDFGPYYLKEIENKISIKKFQALVDDFKKENSPIAKLRDWLTTLSHDKNLAKLQLERINQISKDKWDSKNLYEGTSLKNLIVKKDGLDKTPVYDVLQILSVTDEKEGDIK
>CP032099.1|AXX84702.1|835117_835342_+|hypothetical-protein
MGMLFILGVGFVIFALFKVYTRNDEPIDVGSQENDYERVLFYDALDREEEKNKDTSSFFDYLDNDNSFFSSDDD
>CP032099.1|AXX84703.1|835451_835973_+|porin-family-protein
MKKITKIALAATILTSALNADVVKHFGVTAINSDVKLENADKFTEYGVNFGLTKYFDSNILLGVDASITFGNMDFSSNGQTESILMTGVAGDVKAGYSFFDRKVDLYATIGFAGQGFDNGESDSIGFGYGAGVQYNFAQHWAVAADYKKYDMDFEGLVDYDLNRVGVTVKYLF
>CP032099.1|AXX84704.1|835996_836284_+|hypothetical-protein
MKKKLFLSLGLLFTILAFTGCNEDTNQSKICIYANEEEASKCKAGELSFFAPNSWGSERLPLIAIATYCDTNHQIIMNNSGVICRFINKREGIDK
>CP032099.1|AXX84705.1|836407_836809_+|putative-membrane-protein
MNRNFEPVWAVNSSEVGLIFLGTLLIMAFPILPILDIPTFFVKTELKDFPLIVKIAAYAFFIWFYIYVVIRLEMKLLSIFFNNFVRKHYVKIVYIQTIPLAFLISSFRSESFEAHFSFVITLLLELLFKWLFT
>CP032099.1|AXX84706.1|836858_837782_+|transcriptional-regulator,-YafY-family
MQTKKSILQLQLLKELLEGKKVCLKTFSSKFDISLRSAQRYMQDLIEVFGDNILKDSELYSFVSHSILDKNILNFNKKELENFVDLYSLLDFDFSTKLDDKNRTILQKMEKKYSSTYLIKQNPFENFLQKKELLFQIKDAIKNRRYAKIEYTSDKKYIFDQAKILKIVFAEGNFYIAALTPDEINSGFKFLRLSFVDKIDLYATTFKKEYEAEDFLKKFQTLFSNYKKEPFEVVLKIDESVKRFFINKKFLSSQTILENKDDLIVSFKVTNSMEILPLVKKWLPNIKIVSPKEIKEQFEEELREYLK
>CP032099.1|AXX84707.1|837832_838762_+|paraslipin-family-protein,-SPFH-superfamily
MEATITFAIAIIFFAIVIITRGVKIVSQSDLYVVERLGKFHKVLHGGFHIIIPIIDNVRSILTSREQLVDINRQAVITKDNVNISIDGIVFCKVDDATMATYNVMNFKDAIANLAMTTLRAEIGAMVLDDTLSNRETLNAKLQTELGSAAANWGIKVTRVEIADISVPASIEKAMNMQMEAEREKRAIQTRAEAQKEAQIREAEAFKQSEILKAEAIERMADAKKYEQEKVAAGQKEAMNLINEAMNQNEKAAEFLLAKDRVAAFKALAESSSTDKMILPYEVTQMIGSTSVLGDAFFKGASNTKANNA
>CP032099.1|AXX84708.1|838754_839189_+|putative-membrane-protein
MPSAMEFYTLIALGILLLAFEVFVTSFVIVWFALGFILVGFISLFYGFENILWQLILISVLSMFLLILFRKKALKRFSKSEKDISDNFFNEKGIGEFKLGQIFYKGTFWQIEPSFDIKNLSENEKVKVLKIENNLIYIEKLDKR
>CP032099.1|AXX84709.1|839209_840736_+|radical-SAM-domain/B12-binding-domain-containing-protein-(DUF4080-domain)
MNRQKEIILTTLNSRFSHSSLSLRYLFANLKELKDEAKILEFVINSQTQTIVEEILEYKPKIVLISTYIWNAQDVAEIVKYIKLISPNTIVALGGPEISHLPHRVDFEMADYFMFGEGEISVYNLCKNILGGIRPKDKIIHAKPVEFDKIALPYDYYTDFDIKNRHIYIESSRGCPFTCEFCLSSIDSSMRYLPIDVFLNEIDKLWNRGARNYKFIDRTFNLKISYAKAILDYFLEKDEDYFLHFEVIPDNFPLELRQRLKKFKAGSLQLEVGIQTLNLDVAKNINRNLKIDKIKENLAFLSSETKAHMHIDLIVGLPTETIESFEANLDLLYTLSSGEIQIGILKKLSGTTLNRHDELHGMVYNPNPPYDILKNNLVSFTLMQDMKRFARFWDIVYNSGNFVKTSKLLFKDGKVFKNFFDFSKWLYKRSESTFKISLDRVAEYLFEYLSRDWEEEILVKTILDDVMMIEGRKIPPFLKKYKKYEKDFIQIEQSRANKRQILRIENND
>CP032099.1|AXX84710.1|840728_841430_+|DUF481-domain-containing-protein
MIKNHKKLLILPILLNFATAVENEGKVELSYVNTSGNTQTTTLAADAEVKSKIDDIELKFKGSIIKSKDNNEESANKYELELQSSYMFTDNFYTYLGVNYVKDEFSDYDSRLNIGPGLGYKFINTDDHLLDIKSGVDYSLDKYENGKKNEYAASKSELNYKYKIKEDIEFKQMVNYLVSMEDSEKYFVTSESSVNVKMVGNLSLGVSYKVDYINQTQKEKTDKKFLTSLIYDF
>CP032099.1|AXX84711.1|841577_842369_+|RhuM-family-protein
MSEILIYQNENGNIKVDVMFEDGSIWLSQAQICELFGKAKSTISEHIKAIFEEEELNPISTVRNYRTVQKEGNREVERDIEYYNLDMIIAIGFRVRSSTGTKFRIWANDKLKEYITKGFVLNDERFKNGNSMGYFDELQKRLRDIRISEKFFYQKIKDIYMTSIDYDPKDEKTILGLLVEQYLAFAETMAIQRTPMYMKDWIARLDAVISLNGRELLTHAGKISHEMAIAKSGLEYKKFKDEQKKIEKIQSLKELEEDIKRLK

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Crispr_ID: CP032099_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP032099_2

834111-834648

TypeIII

Consensus_repeat	Method
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	CRISPRCasFinder
ATTACAACATTGACCCGATTATNAGGGGATTGAAAC	CRT
ATTACAACATTGACCCGATTATAAGGGGATTGAAAC	PILER-CR

7 spacers

cas2,cas1,csx1,csm3gr7,csx19,csx10gr5,cas10,WYL

The CRISPR arrays of CP032099_2

>merge|CP032099|2|834111-834648|CRISPRCasFinder,CRT,PILER-CR
ATTACAACATTGACCCGATTATTAGGGGATTGAAACGTAAAAGAAGTATCAGAATGAAATAATTTTTCATTTATTACAACATTGACCCGATTATTAGGGGATTGAAACAATAACTCTTCTTCATCACAATCATCTTTATCATAGATTACAACATTGACCCGATTATTAGGGGATTGAAACAAGATGGAAAAATTCTATCGTGTTGATTTCCTTAAATTACAACATTGACCCGATTATAAGGGGATTGAAACTGAACATCGGCAAATATAGTGATATTAAAAGTGTTATTACAACATTGACCCGATTATAAGGGGATTGAAACCATCTTTTCAAAGATGTCTTTGTTTGTTATTATAAGATTACAACATTGACCCGATTATAAGGGGATTGAAACATCTGAACCAGTCTCTAAAGCTCTTTGAAAGTCTAGGATTACAACATTGACCCGATTATAAGGGGATTGAAACTCTTGTATCCTTTTTTTTGGTTTTTTCTATTCTATATTACAACATTGACCCGATTATTTTTGCCTTTGGCA

>CP032099|2|2|834111-834648|CRISPRCasFinder
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	GTAAAAGAAGTATCAGAATGAAATAATTTTTCATTT
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	AATAACTCTTCTTCATCACAATCATCTTTATCATAG
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	AAGATGGAAAAATTCTATCGTGTTGATTTCCTTAA
ATTACAACATTGACCCGATTATAAGGGGATTGAAAC	TGAACATCGGCAAATATAGTGATATTAAAAGTGTT
ATTACAACATTGACCCGATTATAAGGGGATTGAAAC	CATCTTTTCAAAGATGTCTTTGTTTGTTATTATAAG
ATTACAACATTGACCCGATTATAAGGGGATTGAAAC	ATCTGAACCAGTCTCTAAAGCTCTTTGAAAGTCTAGG
ATTACAACATTGACCCGATTATAAGGGGATTGAAAC	TCTTGTATCCTTTTTTTTGGTTTTTTCTATTCTAT
ATTACAACATTGACCCGATTATTTTTGCCTTTGGCA

>CP032099|2|2|834111-834648|CRT
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	GTAAAAGAAGTATCAGAATGAAATAATTTTTCATTT
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	AATAACTCTTCTTCATCACAATCATCTTTATCATAG
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	AAGATGGAAAAATTCTATCGTGTTGATTTCCTTAA
ATTACAACATTGACCCGATTATAAGGGGATTGAAAC	TGAACATCGGCAAATATAGTGATATTAAAAGTGTT
ATTACAACATTGACCCGATTATAAGGGGATTGAAAC	CATCTTTTCAAAGATGTCTTTGTTTGTTATTATAAG
ATTACAACATTGACCCGATTATAAGGGGATTGAAAC	ATCTGAACCAGTCTCTAAAGCTCTTTGAAAGTCTAGG
ATTACAACATTGACCCGATTATAAGGGGATTGAAAC	TCTTGTATCCTTTTTTTTGGTTTTTTCTATTCTAT
ATTACAACATTGACCCGATTATTTTTGCCTTTGGCA

>CP032099|2|2|834183-834577|PILER-CR
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	AATAACTCTTCTTCATCACAATCATCTTTATCATAG
ATTACAACATTGACCCGATTATTAGGGGATTGAAAC	AAGATGGAAAAATTCTATCGTGTTGATTTCCTTAA
ATTACAACATTGACCCGATTATAAGGGGATTGAAAC	TGAACATCGGCAAATATAGTGATATTAAAAGTGTT
ATTACAACATTGACCCGATTATAAGGGGATTGAAAC	CATCTTTTCAAAGATGTCTTTGTTTGTTATTATAAG
ATTACAACATTGACCCGATTATAAGGGGATTGAAAC	ATCTGAACCAGTCTCTAAAGCTCTTTGAAAGTCTAGG
ATTACAACATTGACCCGATTATAAGGGGATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP032099.1\|AXX84696.1\|828130_828544_+\|CRISPR/Cas-system-associated-RAMP-protein,-type-III	csx19	mkCas0122_csx19_CAS-III-D	gnl\|CDD\|275216
CP032099.1\|AXX84705.1\|836407_836809_+\|putative-membrane-protein	unknown	unknown	unknown
CP032099.1\|AXX84693.1\|824952_825468_+\|CRISPR/Cas-system-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|377130
CP032099.1\|AXX84697.1\|828540_830331_+\|CRISPR/Cas-system-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274902
CP032099.1\|AXX84700.1\|832110_832719_+\|CRISPR/Cas-system-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
CP032099.1\|AXX84709.1\|839209_840736_+\|radical-SAM-domain/B12-binding-domain-containing-protein-(DUF4080-domain)	unknown	unknown	gnl\|CDD\|223963
CP032099.1\|AXX84692.1\|823534_824956_+\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl\|CDD\|187810
CP032099.1\|AXX84707.1\|837832_838762_+\|paraslipin-family-protein,-SPFH-superfamily	unknown	unknown	gnl\|CDD\|223407
CP032099.1\|AXX84704.1\|835996_836284_+\|hypothetical-protein	unknown	unknown	unknown
CP032099.1\|AXX84708.1\|838754_839189_+\|putative-membrane-protein	unknown	unknown	gnl\|CDD\|224501
CP032099.1\|AXX84706.1\|836858_837782_+\|transcriptional-regulator,-YafY-family	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
CP032099.1\|AXX84701.1\|832705_832978_+\|CRISPR/Cas-system-associated-endoribonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
CP032099.1\|AXX84703.1\|835451_835973_+\|porin-family-protein	unknown	unknown	gnl\|CDD\|379226
CP032099.1\|AXX84694.1\|825470_826850_+\|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	gnl\|CDD\|224256
CP032099.1\|AXX84710.1\|840728_841430_+\|DUF481-domain-containing-protein	unknown	unknown	gnl\|CDD\|377313
CP032099.1\|AXX84699.1\|831830_832097_+\|Cas2-family-CRISPR/Cas-system-associated-protein	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256
CP032099.1\|AXX84695.1\|826851_828144_+\|CRISPR/Cas-system-associated-RAMP-protein-Cas7/Csm3,-type-III	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|377130
CP032099.1\|AXX84711.1\|841577_842369_+\|RhuM-family-protein	unknown	unknown	gnl\|CDD\|379118
CP032099.1\|AXX84698.1\|830341_831592_+\|CRISPR/Cas-system-associated-protein-Csx1,-type-III	csx1	pfam09455_csx1_CAS-III	gnl\|CDD\|187863
CP032099.1\|AXX84702.1\|835117_835342_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP032099.1\|AXX84706.1\|836858_837782_+\|transcriptional-regulator,-YafY-family	WYL	pfam13280_WYL_CAS-I:CAS-III	1.1e-23	78.9	0.3
CP032099.1\|AXX84701.1\|832705_832978_+\|CRISPR/Cas-system-associated-endoribonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	8.1e-20	65.7	3.4
CP032099.1\|AXX84694.1\|825470_826850_+\|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	7.8e-65	213.7	1.6
CP032099.1\|AXX84697.1\|828540_830331_+\|CRISPR/Cas-system-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	3.9e-101	334.6	25.7
CP032099.1\|AXX84693.1\|824952_825468_+\|CRISPR/Cas-system-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	1.5e-18	61.7	0.0
CP032099.1\|AXX84700.1\|832110_832719_+\|CRISPR/Cas-system-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	4.2e-44	145.5	1.2
CP032099.1\|AXX84699.1\|831830_832097_+\|Cas2-family-CRISPR/Cas-system-associated-protein	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.6e-11	37.4	0.7
CP032099.1\|AXX84692.1\|823534_824956_+\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	1.8e-79	262.4	7.3
CP032099.1\|AXX84696.1\|828130_828544_+\|CRISPR/Cas-system-associated-RAMP-protein,-type-III	csx19	mkCas0122_csx19_CAS-III-D	9.9e-36	118.0	6.5
CP032099.1\|AXX84698.1\|830341_831592_+\|CRISPR/Cas-system-associated-protein-Csx1,-type-III	csx1	pfam09455_csx1_CAS-III	3.5e-51	169.2	18.7
CP032099.1\|AXX84695.1\|826851_828144_+\|CRISPR/Cas-system-associated-RAMP-protein-Cas7/Csm3,-type-III	csm3gr7	cd09726_csm3gr7_CAS-III-D	7.1e-36	119.0	9.8

Protein	Function_ID	Function_description	E-value
CP032099.1\|AXX84696.1\|828130_828544_+\|CRISPR/Cas-system-associated-RAMP-protein,-type-III	gnl\|CDD\|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	1.56458e-24
CP032099.1\|AXX84693.1\|824952_825468_+\|CRISPR/Cas-system-associated-RAMP-protein	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	8.37768e-09
CP032099.1\|AXX84697.1\|828540_830331_+\|CRISPR/Cas-system-associated-RAMP-protein	gnl\|CDD\|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	1.09039e-92
CP032099.1\|AXX84700.1\|832110_832719_+\|CRISPR/Cas-system-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	8.56387e-43
CP032099.1\|AXX84709.1\|839209_840736_+\|radical-SAM-domain/B12-binding-domain-containing-protein-(DUF4080-domain)	gnl\|CDD\|223963	COG1032, COG1032, Fe-S oxidoreductase [Energy production and conversion].	7.01782e-27
CP032099.1\|AXX84692.1\|823534_824956_+\|hypothetical-protein	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	8.93321e-09
CP032099.1\|AXX84707.1\|837832_838762_+\|paraslipin-family-protein,-SPFH-superfamily	gnl\|CDD\|223407	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones].	6.77029e-52
CP032099.1\|AXX84708.1\|838754_839189_+\|putative-membrane-protein	gnl\|CDD\|224501	COG1585, COG1585, Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	1.28236e-10
CP032099.1\|AXX84706.1\|836858_837782_+\|transcriptional-regulator,-YafY-family	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	5.16111e-18
CP032099.1\|AXX84701.1\|832705_832978_+\|CRISPR/Cas-system-associated-endoribonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.28049e-14
CP032099.1\|AXX84698.1\|830341_831592_+\|CRISPR/Cas-system-associated-protein-Csx1,-type-III	gnl\|CDD\|187863	cd09732, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as TM1812 family.	1.38796e-39
CP032099.1\|AXX84694.1\|825470_826850_+\|hypothetical-protein	gnl\|CDD\|224256	COG1337, COG1337, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	0.00815818
CP032099.1\|AXX84710.1\|840728_841430_+\|DUF481-domain-containing-protein	gnl\|CDD\|377313	pfam04338, DUF481, Protein of unknown function, DUF481. This family includes several proteins of uncharacterized function.	1.5037e-53
CP032099.1\|AXX84699.1\|831830_832097_+\|Cas2-family-CRISPR/Cas-system-associated-protein	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	0.000923357
CP032099.1\|AXX84711.1\|841577_842369_+\|RhuM-family-protein	gnl\|CDD\|379118	pfam13310, Virulence_RhuM, Virulence protein RhuM family. There are currently no experimental data for members of this group or their homologs. However, these proteins are implicated in virulence/pathogenicity because RhuM is encoded in the SPI-3 pathogenicity island in Salmonella typhimurium.	2.33212e-65
CP032099.1\|AXX84703.1\|835451_835973_+\|porin-family-protein	gnl\|CDD\|379226	pfam13505, OMP_b-brl, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	1.93763e-10
CP032099.1\|AXX84695.1\|826851_828144_+\|CRISPR/Cas-system-associated-RAMP-protein-Cas7/Csm3,-type-III	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	8.3242e-16

>CP032099.1|AXX84701.1|832705_832978_+|CRISPR/Cas-system-associated-endoribonuclease-Cas2
MKLHDYIICYDISDKKRLVKISKLLEKTAARIQYSIYFYPKVAKECIDDLVEKLNKLINQEEDDIRIYKIDIKNSIHLKSGIDLQNPFVI
>CP032099.1|AXX84700.1|832110_832719_+|CRISPR/Cas-system-associated-endonuclease-Cas1
MIAKDILLDKVKLHKLHLEKYEIDLNIKLILKKIEKAQNIDELMGIEGSFAKTYFKEFFSLLPKNMHKNKRSKNPPQDPANAVLSLFYTLYYNIISIKLLTHGFEPSIGYLHTPFREHNALASDLMELFRADINEEVIQIFKENLLSLDDFTKKGGVYLKYEARSKIWKRFLELEARLKSKLDKEVANIRAKISKDILDEVA
>CP032099.1|AXX84699.1|831830_832097_+|Cas2-family-CRISPR/Cas-system-associated-protein
MKNYLVLYDIFNTKRAYKIRKYLYKHTTGGQKSALEIPLDEKLSDKLIFKLNSYTKDIDKINIVKIYKNPILLGKASQLNIISNGVIV
>CP032099.1|AXX84698.1|830341_831592_+|CRISPR/Cas-system-associated-protein-Csx1,-type-III
MAKILITLLGTGSKAKGDNTNNNYELADYIIDDKIYEKRAFISSAIAEHYEVDKIFTIGTKQSMWDNLCEFYNTNEEYHFEVLNLKEKELLDEDKLEGLSSAIDKKLQNSGSKCFIIENSESSEEIWQMFEKMLHILDDVDDKDELYFDITHLFRSVSVFSMIIAEFAQITRDIKISGMFYGLLKKGKPSVVVDLSLYFEFLAWTRAIKSLKDYGNASELLKLLESSNQSKEIVNSFKSFAYSLSISDMGELQNSIEILKGKIDKFVLSNNPIVRLISKDLLEFINRFGKIKKDELAKFQFELTKWYSQNNNHAMAYITLAEASVTAVCEANNLDVASMEDRKKAQNILFEYSKWSNDYPKELQKIGETYSKINNIRNNIAHKLSGNSKRSKSTPTNSVENLSNYINILESLLKTK
>CP032099.1|AXX84697.1|828540_830331_+|CRISPR/Cas-system-associated-RAMP-protein
MITAPYNFVPLNKEIFYPSWADDVSHDVPFKDGESGEIDITITAKSPIFIRNHSKDKEKPTDEFCHHINQNGAKEFYIPSSSIKGMVRNVLEILSFSKITINENYKDIFGVRDMSNQKELVGGANGCGFLIKKDDEFYIEDCGQILTISHTNLEEKFKNLKKLESAKEKYNKFGLLKELKFSTYKKIMDIRGRKIPKNMAKFDNNSSLFGKLVFTGNIGNKKHEFIFKTNGKILELDKKVFNNFSNVYFKDENSVDGQFWKQNFPKTLKIPVFYIKDKDSNKIKHIGLTQLFKIAYNKSIFEASKQNIKENKLDLAQTIFGYVSKEKALKGRVQFSHFKSTIQRYEKEVEQVLGTPNPTYYPNYIRQTNTNRDKVNKYITLMDSNAQISGWKRYPLHSSIKNPPLIKKKDGSINHDITTHFKPLSKDTVFKGKLRFHNLKKIEIGALLSAITFHGQSDKYMHNIGMAKSLGYGKIDIKLEPRNLKYTQNEYLKEFENEISKHIPNWRNSEQLKELFAMANRDINIDKNKNLVYQLLENPKPKYKDKNDFTGAKKDKDYLLPYSGIIPNNANKAKQEPNRGDNKMNGIRIVSKVNKK
>CP032099.1|AXX84696.1|828130_828544_+|CRISPR/Cas-system-associated-RAMP-protein,-type-III
MKTYEEIKNFYINLEGKFEGYFQMSDEKLNKVYQEKQTLPSWEDLHEDKNFILEACLFDGNRSITIRNIGNSFVLIDKNISDFKEENITKQSFITNGYKEVIISQIWEEKEDENCLNIKVLKPTIQLFSGFKKGETK
>CP032099.1|AXX84695.1|826851_828144_+|CRISPR/Cas-system-associated-RAMP-protein-Cas7/Csm3,-type-III
MEKYRHIAHIIIEARTALKIGSNSIDALQDSPIQKDWNGLPMILGTSLAGVLRKEFDKTKVNDVFGDEDSKKKESKGSRVIFSNALLLNEDKKVTETLLLEKSDFLKNFEILPIRDHNSMNDKGVTNKHGKFDEEIIYKGTRFKFSIELISNKDDKEEFKSILDELYKNSFRVGAGSSKGYGQIEVLEITYDTFDITSKEYIEFSSSLNKTLKEKYENKSIIDDKYIKYELKLTPDDFFMFGSGYGDEQVDMTPVVEKVIDYENKTLSEEKIVIPASSVKGAISHRTTYHYNLKKGNFIENGVKAQIVEDIFGAKKDKKIDGFKGNILISDLYLEKNDTKIFDHVSIDRFTGGAIEGALFQEKTVASCESFILEILLNKEKIKDEVAIEAFENALKDITTGMLSLGGATTKGHGVFGGIVLKMEKNYENL
>CP032099.1|AXX84694.1|825470_826850_+|hypothetical-protein
MKKIYYKLTFLSDIVLQGSSNTLGKVETLDYITGSSILGIVAKNYDKFENPIDIFHSKKVRFGEATLLSENKECYKAPLCFFAPKEDFDKQEVKNNHFIDYKNQEELDKQYKQIRTGYINSNLDYLNLDFTYTQKAAYDKKNRKSEDGKMYGYNSIQKGTSWIFSLKIDDTINQNDKKLLEDSLVGVRYLGKSKSSSYGKVKIEELKDYKLENIENPITTGVNYIYVKSSLALFDENGMSTFIPTKESLALENAKIVWEETQIKTKTFTPYNSIRECFDFSRNIIQRGSVIALKNISPKDIETLKKGIGAYLNEGYGEVLINPSFLLKEDKFCLNKKDIVYEKIENETSKIDDDLVAFLNNKSEISKKTLTLVEEVEKYIEENKNSFKGVSKSQWGQIRAYTQFHKESYREKIKDFISHGISEKQWKDAKEKLEKLLDEKSLEFIKLFSMTMPKKDLEK
>CP032099.1|AXX84693.1|824952_825468_+|CRISPR/Cas-system-associated-RAMP-protein
MRYKITFLDYWHLSSGLSSGAKADSTVLKDKDGLPYFSGKTIKGLTREMAELTMDEKFINICFGNEGNSAGACYFSDVILDDSTRKIIVDKSLQSNLYTELASTKIDENGIAKTGSLREIEVVIPITLYGTIENIPKEYQTSMINALKSIKRAGLNRNRGLGRCKIEIVGE
>CP032099.1|AXX84692.1|823534_824956_+|hypothetical-protein
MSEYLYGASLQGLQEFIFKTNKLKEIIGASEIIKNFDKLELKKEFDLKEDATIILQAAGNLRVIFKNKEDLEKVVLKLPQYMMLKAYGVTISQAVVEYKNYKDSSQELEKLLKIQRNKSNISLDTHFNIIQQNPRTALPLIDSENDKATAQKIVEFKKFAKEIKKDDKDSIFDISYLSNKKNKIAIIHIDGNGLGNIVKDLTEADIKMFSKKLDDATNEAFKECVEKVFKSEDSKLKKRDVILGGDDVTLICDANQALDFTKYFLELFEEKTKNIYTNKEKNISYDLTACAGVVFCNEKYPFHYAVKLAEDLCSFTKKDSKKYAKEKKLNLAPSSLMFHNIQSSNVESFSKFIEDELTINGIRCDFGPYYLKEIENKISIKKFQALVDDFKKENSPIAKLRDWLTTLSHDKNLAKLQLERINQISKDKWDSKNLYEGTSLKNLIVKKDGLDKTPVYDVLQILSVTDEKEGDIK
>CP032099.1|AXX84702.1|835117_835342_+|hypothetical-protein
MGMLFILGVGFVIFALFKVYTRNDEPIDVGSQENDYERVLFYDALDREEEKNKDTSSFFDYLDNDNSFFSSDDD
>CP032099.1|AXX84703.1|835451_835973_+|porin-family-protein
MKKITKIALAATILTSALNADVVKHFGVTAINSDVKLENADKFTEYGVNFGLTKYFDSNILLGVDASITFGNMDFSSNGQTESILMTGVAGDVKAGYSFFDRKVDLYATIGFAGQGFDNGESDSIGFGYGAGVQYNFAQHWAVAADYKKYDMDFEGLVDYDLNRVGVTVKYLF
>CP032099.1|AXX84704.1|835996_836284_+|hypothetical-protein
MKKKLFLSLGLLFTILAFTGCNEDTNQSKICIYANEEEASKCKAGELSFFAPNSWGSERLPLIAIATYCDTNHQIIMNNSGVICRFINKREGIDK
>CP032099.1|AXX84705.1|836407_836809_+|putative-membrane-protein
MNRNFEPVWAVNSSEVGLIFLGTLLIMAFPILPILDIPTFFVKTELKDFPLIVKIAAYAFFIWFYIYVVIRLEMKLLSIFFNNFVRKHYVKIVYIQTIPLAFLISSFRSESFEAHFSFVITLLLELLFKWLFT
>CP032099.1|AXX84706.1|836858_837782_+|transcriptional-regulator,-YafY-family
MQTKKSILQLQLLKELLEGKKVCLKTFSSKFDISLRSAQRYMQDLIEVFGDNILKDSELYSFVSHSILDKNILNFNKKELENFVDLYSLLDFDFSTKLDDKNRTILQKMEKKYSSTYLIKQNPFENFLQKKELLFQIKDAIKNRRYAKIEYTSDKKYIFDQAKILKIVFAEGNFYIAALTPDEINSGFKFLRLSFVDKIDLYATTFKKEYEAEDFLKKFQTLFSNYKKEPFEVVLKIDESVKRFFINKKFLSSQTILENKDDLIVSFKVTNSMEILPLVKKWLPNIKIVSPKEIKEQFEEELREYLK
>CP032099.1|AXX84707.1|837832_838762_+|paraslipin-family-protein,-SPFH-superfamily
MEATITFAIAIIFFAIVIITRGVKIVSQSDLYVVERLGKFHKVLHGGFHIIIPIIDNVRSILTSREQLVDINRQAVITKDNVNISIDGIVFCKVDDATMATYNVMNFKDAIANLAMTTLRAEIGAMVLDDTLSNRETLNAKLQTELGSAAANWGIKVTRVEIADISVPASIEKAMNMQMEAEREKRAIQTRAEAQKEAQIREAEAFKQSEILKAEAIERMADAKKYEQEKVAAGQKEAMNLINEAMNQNEKAAEFLLAKDRVAAFKALAESSSTDKMILPYEVTQMIGSTSVLGDAFFKGASNTKANNA
>CP032099.1|AXX84708.1|838754_839189_+|putative-membrane-protein
MPSAMEFYTLIALGILLLAFEVFVTSFVIVWFALGFILVGFISLFYGFENILWQLILISVLSMFLLILFRKKALKRFSKSEKDISDNFFNEKGIGEFKLGQIFYKGTFWQIEPSFDIKNLSENEKVKVLKIENNLIYIEKLDKR
>CP032099.1|AXX84709.1|839209_840736_+|radical-SAM-domain/B12-binding-domain-containing-protein-(DUF4080-domain)
MNRQKEIILTTLNSRFSHSSLSLRYLFANLKELKDEAKILEFVINSQTQTIVEEILEYKPKIVLISTYIWNAQDVAEIVKYIKLISPNTIVALGGPEISHLPHRVDFEMADYFMFGEGEISVYNLCKNILGGIRPKDKIIHAKPVEFDKIALPYDYYTDFDIKNRHIYIESSRGCPFTCEFCLSSIDSSMRYLPIDVFLNEIDKLWNRGARNYKFIDRTFNLKISYAKAILDYFLEKDEDYFLHFEVIPDNFPLELRQRLKKFKAGSLQLEVGIQTLNLDVAKNINRNLKIDKIKENLAFLSSETKAHMHIDLIVGLPTETIESFEANLDLLYTLSSGEIQIGILKKLSGTTLNRHDELHGMVYNPNPPYDILKNNLVSFTLMQDMKRFARFWDIVYNSGNFVKTSKLLFKDGKVFKNFFDFSKWLYKRSESTFKISLDRVAEYLFEYLSRDWEEEILVKTILDDVMMIEGRKIPPFLKKYKKYEKDFIQIEQSRANKRQILRIENND
>CP032099.1|AXX84710.1|840728_841430_+|DUF481-domain-containing-protein
MIKNHKKLLILPILLNFATAVENEGKVELSYVNTSGNTQTTTLAADAEVKSKIDDIELKFKGSIIKSKDNNEESANKYELELQSSYMFTDNFYTYLGVNYVKDEFSDYDSRLNIGPGLGYKFINTDDHLLDIKSGVDYSLDKYENGKKNEYAASKSELNYKYKIKEDIEFKQMVNYLVSMEDSEKYFVTSESSVNVKMVGNLSLGVSYKVDYINQTQKEKTDKKFLTSLIYDF
>CP032099.1|AXX84711.1|841577_842369_+|RhuM-family-protein
MSEILIYQNENGNIKVDVMFEDGSIWLSQAQICELFGKAKSTISEHIKAIFEEEELNPISTVRNYRTVQKEGNREVERDIEYYNLDMIIAIGFRVRSSTGTKFRIWANDKLKEYITKGFVLNDERFKNGNSMGYFDELQKRLRDIRISEKFFYQKIKDIYMTSIDYDPKDEKTILGLLVEQYLAFAETMAIQRTPMYMKDWIARLDAVISLNGRELLTHAGKISHEMAIAKSGLEYKKFKDEQKKIEKIQSLKELEEDIKRLK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP032099_1	1.7\|833642\|34\|CP032099\|CRISPRCasFinder,CRT	833642-833675	34	MN694805	Marine virus AFVG_250M201, complete genome	14306-14339	7	0.794
CP032099_2	2.2\|834219\|36\|CP032099\|CRISPRCasFinder,CRT,PILER-CR	834219-834254	36	NZ_CP015634	Borrelia turicatae strain BTE5EL plasmid lp40	36983-37018	7	0.806
CP032099_1	1.1\|833225\|33\|CP032099\|CRISPRCasFinder,CRT	833225-833257	33	MN692961	Marine virus AFVG_117M41, complete genome	24320-24352	8	0.758
CP032099_2	2.2\|834219\|36\|CP032099\|CRISPRCasFinder,CRT,PILER-CR	834219-834254	36	NC_011255	Borrelia recurrentis A1 plasmid pl35, complete sequence	34113-34148	8	0.778
CP032099_2	2.2\|834219\|36\|CP032099\|CRISPRCasFinder,CRT,PILER-CR	834219-834254	36	NC_011255	Borrelia recurrentis A1 plasmid pl35, complete sequence	1245-1280	8	0.778
CP032099_2	2.7\|834578\|35\|CP032099\|CRISPRCasFinder,CRT	834578-834612	35	MN694719	Marine virus AFVG_250M42, complete genome	20345-20379	8	0.771
CP032099_2	2.7\|834578\|35\|CP032099\|CRISPRCasFinder,CRT	834578-834612	35	MN694070	Marine virus AFVG_250M43, complete genome	19397-19431	8	0.771
CP032099_2	2.7\|834578\|35\|CP032099\|CRISPRCasFinder,CRT	834578-834612	35	MN693285	Marine virus AFVG_25M368, complete genome	51160-51194	8	0.771
CP032099_2	2.7\|834578\|35\|CP032099\|CRISPRCasFinder,CRT	834578-834612	35	NZ_CP043635	Empedobacter brevis strain SE1-3 plasmid pSE1-3-9kb, complete sequence	4060-4094	9	0.743
CP032099_2	2.7\|834578\|35\|CP032099\|CRISPRCasFinder,CRT	834578-834612	35	NZ_CP043636	Empedobacter brevis strain SE1-3 plasmid pSE1-3-20kb, complete sequence	13079-13113	9	0.743
CP032099_2	2.7\|834578\|35\|CP032099\|CRISPRCasFinder,CRT	834578-834612	35	MN694386	Marine virus AFVG_250M1120, complete genome	6057-6091	10	0.714

1. spacer 1.7|833642|34|CP032099|CRISPRCasFinder,CRT matches to MN694805 (Marine virus AFVG_250M201, complete genome) position: , mismatch: 7, identity: 0.794

aatattctttaaaggctctactgataagaacttt	CRISPR spacer
aatattctttaaagtctcttctgatatatcctta	Protospacer
************** **** ****** .  ***

2. spacer 2.2|834219|36|CP032099|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015634 (Borrelia turicatae strain BTE5EL plasmid lp40) position: , mismatch: 7, identity: 0.806

aataactcttcttcatcacaatcatctttatcatag	CRISPR spacer
ttttcctcttcttcatcataatcatcattatcatat	Protospacer
  *  *************.******* ********

3. spacer 1.1|833225|33|CP032099|CRISPRCasFinder,CRT matches to MN692961 (Marine virus AFVG_117M41, complete genome) position: , mismatch: 8, identity: 0.758

atagctttttcgttatttattactatcatttaa	CRISPR spacer
atagcttttacgttatttattgcttggtctgaa	Protospacer
********* ***********.**    .* **

4. spacer 2.2|834219|36|CP032099|CRISPRCasFinder,CRT,PILER-CR matches to NC_011255 (Borrelia recurrentis A1 plasmid pl35, complete sequence) position: , mismatch: 8, identity: 0.778

aataactcttcttcatcacaatcatctttatcatag	CRISPR spacer
ctctcctcttcttcatcatattcatctttatcatat	Protospacer
  .  *************.* **************

5. spacer 2.2|834219|36|CP032099|CRISPRCasFinder,CRT,PILER-CR matches to NC_011255 (Borrelia recurrentis A1 plasmid pl35, complete sequence) position: , mismatch: 8, identity: 0.778

aataactcttcttcatcacaatcatctttatcatag	CRISPR spacer
ctctcctcttcttcatcatattcatctttatcatat	Protospacer
  .  *************.* **************

6. spacer 2.7|834578|35|CP032099|CRISPRCasFinder,CRT matches to MN694719 (Marine virus AFVG_250M42, complete genome) position: , mismatch: 8, identity: 0.771

tcttgtatccttttttttggttttttctattctat	CRISPR spacer
gttcgtatccctttttttggtttgttctagtgttt	Protospacer
 .*.******.************ ***** * * *

7. spacer 2.7|834578|35|CP032099|CRISPRCasFinder,CRT matches to MN694070 (Marine virus AFVG_250M43, complete genome) position: , mismatch: 8, identity: 0.771

tcttgtatccttttttttggttttttctattctat	CRISPR spacer
gttcgtatccctttttttggtttgttctagtgttt	Protospacer
 .*.******.************ ***** * * *

8. spacer 2.7|834578|35|CP032099|CRISPRCasFinder,CRT matches to MN693285 (Marine virus AFVG_25M368, complete genome) position: , mismatch: 8, identity: 0.771

tcttgtatccttttttttggttttttctattctat	CRISPR spacer
tcttgtatccttttctttggtctttctctatcttt	Protospacer
**************.******.***...  *** *

9. spacer 2.7|834578|35|CP032099|CRISPRCasFinder,CRT matches to NZ_CP043635 (Empedobacter brevis strain SE1-3 plasmid pSE1-3-9kb, complete sequence) position: , mismatch: 9, identity: 0.743

tcttgtatccttttttttggttttttctattctat	CRISPR spacer
aatggctttcttttttttcgttttttcttttctaa	Protospacer
  * *. *.********* ********* *****

10. spacer 2.7|834578|35|CP032099|CRISPRCasFinder,CRT matches to NZ_CP043636 (Empedobacter brevis strain SE1-3 plasmid pSE1-3-20kb, complete sequence) position: , mismatch: 9, identity: 0.743

tcttgtatccttttttttggttttttctattctat	CRISPR spacer
aatggctttcttttttttcgttttttcttttctaa	Protospacer
  * *. *.********* ********* *****

11. spacer 2.7|834578|35|CP032099|CRISPRCasFinder,CRT matches to MN694386 (Marine virus AFVG_250M1120, complete genome) position: , mismatch: 10, identity: 0.714

tcttgtatccttttttttggttttttctattctat	CRISPR spacer
gcttgtatcctttctcttggttttttaaatatagg	Protospacer
 ************.*.**********  ** . .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

702150 : 760723

Escherichia_phage(33.33%)

transposase,plate,integrase

attL 694951:694968|attR 741507:741524

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
694951:694968	attL	NA	NA	NA	NA
AXX84576.1\|702150_703236_+\|integrase	site-specific tyrosine recombinase, phage integrase family (INT_Rci_Hp1_C domain)	A0A067ZJC0	Vibrio_phage	3.0e-40	34.6
AXX84577.1\|703964_704201_+	hypothetical protein	NA	NA	NA	NA
AXX84578.1\|704422_705940_-	hypothetical protein	NA	NA	NA	NA
AXX84579.1\|706117_706930_-	hypothetical protein	NA	NA	NA	NA
AXX84580.1\|707551_707902_-	hypothetical protein	NA	NA	NA	NA
AXX84581.1\|708204_709818_+	hypothetical protein	NA	NA	NA	NA
AXX84582.1\|710302_714400_+	hypothetical protein	NA	NA	NA	NA
AXX84583.1\|714643_715669_-	hypothetical protein	NA	NA	NA	NA
AXX84584.1\|715690_716653_-	hypothetical protein	NA	NA	NA	NA
AXX84585.1\|716731_717379_-	hypothetical protein	NA	NA	NA	NA
AXX84586.1\|717400_717757_-	hypothetical protein	NA	NA	NA	NA
AXX84587.1\|718606_719455_-	hypothetical protein	NA	NA	NA	NA
AXX84588.1\|719514_720465_-	type IIP restriction/modification system, restriction endonuclease, PstI family	A0A0P0ZG22	Escherichia_phage	6.6e-60	38.9
AXX84589.1\|720382_721867_-	type IIP restriction/modification system, DNA methyltransferase	A0A2R2Z316	Escherichia_phage	5.3e-40	29.7
AXX84590.1\|722430_722994_+	resolvase	M9Q1K0	Clostridium_phage	1.2e-29	42.9
AXX84591.1\|723494_723707_+	hypothetical protein	NA	NA	NA	NA
AXX84592.1\|723852_724032_+	hypothetical protein	NA	NA	NA	NA
AXX84593.1\|724084_724333_+	transcriptional regulator, XRE family	NA	NA	NA	NA
AXX84594.1\|724350_724569_-	hypothetical protein	NA	NA	NA	NA
AXX84595.1\|724709_724991_+	hypothetical protein	NA	NA	NA	NA
AXX84596.1\|725003_725282_+	putative membrane protein	NA	NA	NA	NA
AXX84597.1\|725284_725569_+	hypothetical protein	NA	NA	NA	NA
AXX84598.1\|725571_725844_+	putative membrane protein	NA	NA	NA	NA
AXX84599.1\|727213_727468_+	hypothetical protein	NA	NA	NA	NA
AXX84600.1\|727539_728193_+	zeta toxin domain-containing protein	NA	NA	NA	NA
AXX84601.1\|728189_728408_+	hypothetical protein	NA	NA	NA	NA
AXX84602.1\|729448_731293_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.4e-34	29.0
AXX84603.1\|731682_732246_+	transcriptional regulator, XRE family	NA	NA	NA	NA
AXX84604.1\|732246_733014_+	hypothetical protein	NA	NA	NA	NA
AXX84605.1\|733035_733221_-	putative membrane protein	NA	NA	NA	NA
AXX84606.1\|734434_735739_+	putative membrane protein	NA	NA	NA	NA
AXX84607.1\|735761_738116_+	hypothetical protein	NA	NA	NA	NA
AXX84608.1\|738188_738428_+	hypothetical protein	NA	NA	NA	NA
AXX84609.1\|738427_739639_+	putative membrane protein	NA	NA	NA	NA
AXX84610.1\|739694_740915_+\|transposase	transposase, IS256 family	A0A218MNI5	uncultured_virus	1.1e-70	67.9
AXX84611.1\|741032_741395_-	putative membrane protein	NA	NA	NA	NA
AXX84612.1\|741396_742254_-	hypothetical protein	NA	NA	NA	NA
741507:741524	attR	NA	NA	NA	NA
AXX84613.1\|742962_743220_-	putative membrane protein	NA	NA	NA	NA
AXX84614.1\|743229_743550_-	putative membrane protein	NA	NA	NA	NA
AXX84615.1\|743539_744400_-	hypothetical protein	NA	NA	NA	NA
AXX84616.1\|744386_747284_-	type VI secretion system, syringe needle protein	NA	NA	NA	NA
AXX84617.1\|747385_747910_-	type VI secretion system, inner tube protein	NA	NA	NA	NA
AXX84618.1\|748073_749357_-	hypothetical protein	NA	NA	NA	NA
AXX84619.1\|749375_750248_-	tetratricopeptide repeat protein	NA	NA	NA	NA
AXX84620.1\|750260_753857_-	putative membrane protein	NA	NA	NA	NA
AXX84621.1\|754047_755550_+\|plate	type VI secretion system, baseplate protein	NA	NA	NA	NA
AXX84622.1\|755562_756051_+	type VI secretion system, tubular sheath protein	NA	NA	NA	NA
AXX84623.1\|756061_757534_+	type VI secretion system, tubular sheath protein	NA	NA	NA	NA
AXX84624.1\|757536_757947_+\|plate	type VI secretion system, baseplate protein	NA	NA	NA	NA
AXX84625.1\|757947_759720_+\|plate	type VI secretion system, baseplate protein	NA	NA	NA	NA
AXX84626.1\|759721_760723_+\|plate	type VI secretion system, baseplate protein	NA	NA	NA	NA

DBSCAN-SWA_2

1098205 : 1104432

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXX84956.1\|1098205_1099309_-	dTDP-4-amino-4,6-dideoxygalactose transaminase	A0A2K9L0G1	Tupanvirus	1.0e-32	32.0
AXX84957.1\|1099308_1099821_-	WxcM-like sugar acyltransferase	NA	NA	NA	NA
AXX84958.1\|1099810_1100218_-	WxcM-like domain-containing protein	NA	NA	NA	NA
AXX84959.1\|1100214_1101258_-	dTDP-D-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.9e-76	46.8
AXX84960.1\|1101259_1102081_-	KilA-N domain-containing protein	Q4ZC41	Staphylococcus_virus	1.6e-86	57.8
AXX84961.1\|1102077_1102971_-	dTDP-4-dehydrorhamnose reductase	I7HXC9	Enterobacteria_phage	6.7e-38	39.4
AXX84962.1\|1102963_1103539_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A1D8EQH2	Escherichia_phage	3.2e-33	46.5
AXX84963.1\|1103541_1104432_-	glucose-1-phosphate thymidylyltransferase, short form	I7I009	Enterobacteria_phage	3.8e-102	60.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP032099

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection