CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
CP032309	Enterococcus faecium strain HY07 plasmid unnamed1, complete sequence	0 crisprs	NA	0	0
CP032307	Enterococcus faecium strain HY07 plasmid unnamed2, complete sequence	0 crisprs	cas14j,csa3	0	4
CP032308	Enterococcus faecium strain HY07 chromosome, complete genome	2 crisprs	cas9,cas1,cas2,csn2,DEDDh,cas3,csa3,DinG,cas14j	5	5

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

15753 : 58679

Streptococcus_phage(25.0%)

protease,holin,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYA32959.1\|15753_16713_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.0e-31	35.5
AYA32960.1\|16893_17589_+	hypothetical protein	NA	NA	NA	NA
AYA32961.1\|17625_18123_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AYA32962.1\|18178_19087_-\|transposase	IS982 family transposase	NA	NA	NA	NA
AYA32963.1\|19246_19558_-	hypothetical protein	NA	NA	NA	NA
AYA32964.1\|19547_19730_-	enterocin	NA	NA	NA	NA
AYA32965.1\|20071_20305_-	DUF2786 domain-containing protein	NA	NA	NA	NA
AYA32966.1\|20314_20581_-	hypothetical protein	NA	NA	NA	NA
AYA32967.1\|20562_20958_-	hypothetical protein	NA	NA	NA	NA
AYA32968.1\|21218_21419_-	hypothetical protein	NA	NA	NA	NA
AYA32969.1\|21638_22076_-	hypothetical protein	NA	NA	NA	NA
AYA32970.1\|22091_22343_-	hypothetical protein	NA	NA	NA	NA
AYA32971.1\|22342_22549_-	DNA helicase UvrA	NA	NA	NA	NA
AYA32972.1\|22997_23258_-	hypothetical protein	A0A0S2MYI8	Enterococcus_phage	1.2e-11	51.4
AYA32973.1\|23412_23535_+\|holin	putative holin-like toxin	NA	NA	NA	NA
AYA32974.1\|23693_23951_-	hypothetical protein	NA	NA	NA	NA
AYA32975.1\|23972_24458_-	single-stranded DNA-binding protein	Q938M7	Temperate_phage	7.5e-44	60.5
AYA32976.1\|24460_25360_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
AYA32977.1\|25372_25969_-	transcriptional regulator	NA	NA	NA	NA
AYA32978.1\|26214_28419_-	type IA DNA topoisomerase	A0A1X9I6W8	Streptococcus_phage	9.4e-118	51.3
AYA32979.1\|28429_29899_-	hypothetical protein	NA	NA	NA	NA
AYA32980.1\|29959_32332_-	hypothetical protein	B5SP25	Lactococcus_phage	2.3e-13	32.5
AYA32981.1\|32344_32539_-	hypothetical protein	NA	NA	NA	NA
AYA32982.1\|32678_33014_-	hypothetical protein	NA	NA	NA	NA
AYA32983.1\|33025_34618_-	hypothetical protein	NA	NA	NA	NA
AYA32984.1\|34636_35059_-	hypothetical protein	NA	NA	NA	NA
AYA32985.1\|35060_35357_-	hypothetical protein	NA	NA	NA	NA
AYA32986.1\|35871_36102_-	hypothetical protein	NA	NA	NA	NA
AYA32987.1\|36124_36931_-	hypothetical protein	NA	NA	NA	NA
AYA32988.1\|36941_37586_-	hypothetical protein	NA	NA	NA	NA
AYA32989.1\|37601_38807_-	peptidase M23	Q6SEC2	Lactobacillus_prophage	5.6e-32	42.4
AYA32990.1\|38806_40831_-	ATPase	NA	NA	NA	NA
AYA32991.1\|40993_41587_-	hypothetical protein	NA	NA	NA	NA
AYA32992.1\|41587_41920_-	hypothetical protein	NA	NA	NA	NA
AYA32993.1\|41971_44362_-	hypothetical protein	NA	NA	NA	NA
AYA32994.1\|44358_46968_-	type IV secretory protein	NA	NA	NA	NA
AYA32995.1\|46967_49022_-	hypothetical protein	NA	NA	NA	NA
AYA32996.1\|49091_49394_-	hypothetical protein	NA	NA	NA	NA
AYA32997.1\|49411_49654_-	hypothetical protein	NA	NA	NA	NA
AYA32998.1\|49650_50109_-	hypothetical protein	NA	NA	NA	NA
AYA32999.1\|50296_50506_+	hypothetical protein	NA	NA	NA	NA
AYA33000.1\|50625_52677_+\|protease	serine protease	NA	NA	NA	NA
AYA33001.1\|52712_54824_-	isopeptide-forming domain-containing fimbrial protein	NA	NA	NA	NA
AYA33002.1\|54854_55103_-	hypothetical protein	NA	NA	NA	NA
AYA33003.1\|55112_55940_-	hypothetical protein	NA	NA	NA	NA
AYA33004.1\|55936_56692_-	class C sortase	NA	NA	NA	NA
AYA33005.1\|56704_57082_-	peptidase	NA	NA	NA	NA
AYA33006.1\|57135_58254_-\|transposase	transposase	A0A286QMQ9	Streptococcus_phage	1.5e-95	50.8
AYA33007.1\|58277_58679_-\|transposase	IS200/IS605 family transposase	Q332K6	Clostridium_botulinum_C_phage	6.9e-43	62.4

DBSCAN-SWA_2

70273 : 128241

Streptococcus_phage(22.22%)

integrase,transposase

attL 75629:75651|attR 132825:132847

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYA33019.1\|70273_71182_+\|transposase	IS982 family transposase	NA	NA	NA	NA
AYA33020.1\|71268_72123_+	AraC family transcriptional regulator	NA	NA	NA	NA
AYA33021.1\|72219_74469_+	alpha-galactosidase	NA	NA	NA	NA
AYA33022.1\|74471_75647_+	MFS transporter	NA	NA	NA	NA
75629:75651	attL	NA	NA	NA	NA
AYA33023.1\|75649_76558_-\|transposase	IS982-like element ISEfm1 family transposase	NA	NA	NA	NA
AYA33024.1\|76791_77055_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
AYA33025.1\|77054_77327_+	Txe/YoeB family addiction module toxin	NA	NA	NA	NA
AYA33026.1\|77403_77733_+	AbrB family transcriptional regulator	NA	NA	NA	NA
AYA33027.1\|77722_78010_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
AYA33028.1\|78295_79153_+	ParA family protein	F0PIG8	Enterococcus_phage	8.1e-33	30.7
AYA33029.1\|79153_79702_+	hypothetical protein	NA	NA	NA	NA
AYA33030.1\|80331_81012_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	9.4e-109	83.2
AYA33031.1\|81776_82784_-	LacI family transcriptional regulator	NA	NA	NA	NA
AYA33032.1\|83250_84657_+	6-phospho-beta-galactosidase	A0A0B5JD41	Pandoravirus	3.4e-44	30.2
AYA33033.1\|84679_85003_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
AYA33034.1\|85013_86696_+	PTS lactose transporter subunit IIBC	NA	NA	NA	NA
AYA33035.1\|88320_89073_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-17	30.9
AYA33036.1\|89665_91123_-	PTS glucitol transporter subunit IIA	NA	NA	NA	NA
AYA33037.1\|91144_91447_-	PTS fructose transporter subunit IIB	NA	NA	NA	NA
AYA33038.1\|91503_91983_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
AYA33039.1\|92147_92921_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.3e-18	28.1
AYA33040.1\|92940_93369_+	galactose-6-phosphate isomerase subunit LacA	NA	NA	NA	NA
AYA33041.1\|93387_93903_+	galactose-6-phosphate isomerase subunit LacB	A0A222YX14	Synechococcus_phage	9.5e-05	29.0
AYA33042.1\|93915_94842_+	tagatose-6-phosphate kinase	NA	NA	NA	NA
AYA33043.1\|94854_95841_+	tagatose-bisphosphate aldolase	NA	NA	NA	NA
AYA33044.1\|96296_96965_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	8.8e-27	32.4
AYA33045.1\|96955_98089_+	ATP-binding protein	NA	NA	NA	NA
AYA33046.1\|99216_99459_-	hypothetical protein	NA	NA	NA	NA
AYA33047.1\|99451_100237_-	SinI family restriction endonuclease	NA	NA	NA	NA
AYA33048.1\|100360_101956_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.3e-126	51.1
AYA33049.1\|101945_102806_+	restriction endonuclease subunit S	NA	NA	NA	NA
AYA33050.1\|103976_105132_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.8e-75	51.3
AYA33051.1\|106612_107035_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
AYA33052.1\|107460_108291_-	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
AYA33053.1\|108290_109040_-	ABC transporter permease	NA	NA	NA	NA
AYA33054.1\|109032_109950_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	4.6e-42	43.2
AYA33055.1\|110132_110747_-	XRE family transcriptional regulator	A0A139ZPI6	Marinitoga_camini_virus	5.5e-07	46.8
AYA33056.1\|110736_110934_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AYA33057.1\|111099_111459_+	XRE family transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	4.4e-17	40.4
AYA33058.1\|111876_112143_+	hypothetical protein	A0A2H4PQP5	Staphylococcus_phage	6.2e-08	36.0
AYA33059.1\|112171_113149_+	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
AYA33060.1\|113329_114163_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
AYA33061.1\|114168_114759_+\|integrase	site-specific integrase	D2XR58	Bacillus_phage	8.3e-21	33.1
AYA33062.1\|115339_116479_+	MFS transporter	NA	NA	NA	NA
AYA33181.1\|116930_117323_+	recombinase family protein	NA	NA	NA	NA
AYA33063.1\|117322_118624_+	DNA topoisomerase	A0A1X9I6W8	Streptococcus_phage	1.9e-105	99.0
AYA33064.1\|118747_120538_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
AYA33065.1\|120891_122244_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	8.0e-43	30.2
AYA33066.1\|122260_123229_+	thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha	NA	NA	NA	NA
AYA33067.1\|123253_124285_+	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
AYA33068.1\|124302_125508_+	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
AYA33069.1\|125794_126859_+	2,3-butanediol dehydrogenase	E3SJ82	Synechococcus_phage	7.2e-15	27.7
AYA33070.1\|127554_128241_-\|transposase	IS6-like element ISEnfa1 family transposase	A0A1X9I6C6	Streptococcus_phage	4.8e-113	88.5
132825:132847	attR	NA	NA	NA	NA

DBSCAN-SWA_3

131826 : 195717

Streptococcus_phage(35.71%)

bacteriocin,integrase,transposase

attL 132430:132489|attR 182465:182881

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYA33073.1\|131826_132735_-\|transposase	IS982 family transposase	NA	NA	NA	NA
132430:132489	attL	NA	NA	NA	NA
AYA33074.1\|132861_133101_+	hypothetical protein	NA	NA	NA	NA
AYA33075.1\|133102_134401_+	hypothetical protein	NA	NA	NA	NA
AYA33076.1\|136356_137547_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	1.7e-28	24.6
AYA33077.1\|138081_138654_+	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	3.9e-23	42.6
AYA33078.1\|138798_139503_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
AYA33079.1\|139730_140069_+	hypothetical protein	NA	NA	NA	NA
AYA33080.1\|141055_141289_+	copper chaperone	NA	NA	NA	NA
AYA33081.1\|141486_143391_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	2.4e-101	35.8
AYA33082.1\|143739_144912_+\|transposase	IS256-like element IS1542 family transposase	A0A0N9STL0	Staphylococcus_phage	2.2e-121	88.4
AYA33083.1\|145188_145542_+	transcriptional regulator	E4ZFI8	Streptococcus_phage	4.4e-17	40.7
AYA33084.1\|145566_146184_+	cadmium resistance protein CadD	NA	NA	NA	NA
AYA33085.1\|147386_147809_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
AYA33086.1\|147842_148340_+	PTS mannose/fructose/sorbose transporter subunit IIB	NA	NA	NA	NA
AYA33087.1\|148360_149179_+	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
AYA33088.1\|149175_150006_+	PTS system mannose/fructose/sorbose family transporter subunit IID	NA	NA	NA	NA
AYA33089.1\|150182_152708_+	AAA family ATPase	NA	NA	NA	NA
AYA33090.1\|153121_153808_-\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	2.2e-126	99.1
AYA33091.1\|154383_155409_+	LacI family transcriptional regulator	NA	NA	NA	NA
AYA33092.1\|155702_156812_+	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
AYA33093.1\|157806_158631_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
AYA33094.1\|158662_159991_+	alpha-glucosidase/alpha-galactosidase	NA	NA	NA	NA
AYA33095.1\|160284_161544_+	extracellular solute-binding protein	NA	NA	NA	NA
AYA33096.1\|161553_162426_+	sugar ABC transporter permease	NA	NA	NA	NA
AYA33097.1\|162437_163268_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
AYA33098.1\|163307_165491_+	alpha-galactosidase	NA	NA	NA	NA
AYA33099.1\|165551_165707_+	oligo-1,6-glucosidase	NA	NA	NA	NA
AYA33100.1\|165802_166771_+	oligo-1,6-glucosidase	NA	NA	NA	NA
AYA33101.1\|166767_168228_+	sucrose phosphorylase	NA	NA	NA	NA
AYA33102.1\|169732_169942_+	DUF3173 domain-containing protein	NA	NA	NA	NA
AYA33103.1\|169934_170084_+\|integrase	integrase	NA	NA	NA	NA
AYA33104.1\|170118_170247_+\|integrase	integrase	NA	NA	NA	NA
AYA33105.1\|170237_170903_+\|integrase	site-specific integrase	A0A0S2MV79	Bacillus_phage	5.2e-19	31.1
AYA33106.1\|171186_172272_-	tyrosine recombinase XerS	NA	NA	NA	NA
AYA33107.1\|172605_172839_+	addiction module antitoxin	NA	NA	NA	NA
AYA33108.1\|172835_173243_+	type II toxin-antitoxin system death-on-curing family toxin	A0A0N9SKD8	Staphylococcus_phage	4.0e-14	38.9
AYA33109.1\|173681_174860_+\|transposase	IS256-like element ISEf1 family transposase	A0A220NQR7	Corynebacterium_phage	1.8e-30	25.6
AYA33110.1\|175041_175551_-	hypothetical protein	NA	NA	NA	NA
AYA33183.1\|175691_176042_-	hypothetical protein	NA	NA	NA	NA
AYA33111.1\|176034_177360_-	Y-family DNA polymerase	M1Q231	Streptococcus_phage	7.0e-100	44.5
AYA33184.1\|177697_177988_+	hypothetical protein	NA	NA	NA	NA
AYA33185.1\|178243_178555_-	hypothetical protein	NA	NA	NA	NA
AYA33112.1\|180344_180542_+	hypothetical protein	NA	NA	NA	NA
AYA33186.1\|180634_180799_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
AYA33113.1\|180803_181070_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
AYA33114.1\|181707_182396_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	2.7e-124	98.2
AYA33115.1\|182884_183229_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
182465:182881	attR	NA	NA	NA	NA
AYA33116.1\|183222_183486_-	PbsX family transcriptional regulator	NA	NA	NA	NA
AYA33117.1\|184633_184876_-	hypothetical protein	NA	NA	NA	NA
AYA33118.1\|186836_187790_-	ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	3.5e-29	27.5
AYA33119.1\|187799_189956_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	1.5e-240	58.2
AYA33120.1\|190105_190573_-	ribonucleotide reductase assembly protein NrdI	NA	NA	NA	NA
AYA33121.1\|190741_191413_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
AYA33122.1\|191510_192680_-\|transposase	IS256 family transposase	NA	NA	NA	NA
AYA33123.1\|192841_193930_+	hypothetical protein	NA	NA	NA	NA
AYA33124.1\|194070_195717_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	8.0e-146	49.7

DBSCAN-SWA_4

207696 : 217450

Leptospira_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYA33132.1\|207696_208989_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.9e-55	38.1
AYA33188.1\|209082_209181_+	hypothetical protein	NA	NA	NA	NA
AYA33189.1\|209177_209615_-	hypothetical protein	NA	NA	NA	NA
AYA33133.1\|211038_211233_+	hypothetical protein	NA	NA	NA	NA
AYA33134.1\|211222_211576_+	IS66 family insertion sequence hypothetical protein	S5VXZ8	Leptospira_phage	5.7e-17	38.7
AYA33135.1\|211677_213225_+\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	1.7e-44	28.9
AYA33136.1\|213867_214827_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	6.1e-37	37.0
AYA33137.1\|215046_216009_-	LacI family transcriptional regulator	C6ZCU4	Enterobacteria_phage	6.8e-20	25.5
AYA33138.1\|216010_217450_-	sucrose-6-phosphate hydrolase	S6ATV4	Bacillus_phage	1.8e-16	25.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP032308

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP032308_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP032308_2

428382-428473

TypeII

II-A

Consensus_repeat	Method
GGTTTTAGAGCTATGCTGATTTGAAT	CRISPRCasFinder

1 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of CP032308_2

>merge|CP032308|2|428382-428473|CRISPRCasFinder
GGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACAAAGGAGCAATTGAAAAAGGAAACGGCGCGGTTTTAGAGCTATGCTGATTTGAAT

>CP032308|2|1|428382-428473|CRISPRCasFinder
GGTTTTAGAGCTATGCTGATTTGAAT	GCTTCCAAAACAAAGGAGCAATTGAAAAAGGAAACGGCGC
GGTTTTAGAGCTATGCTGATTTGAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP032308.1\|AYA33574.1\|436366_437224_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
CP032308.1\|AYA33561.1\|419743_419935_-\|hypothetical-protein	unknown	unknown	unknown
CP032308.1\|AYA33577.1\|440009_440309_+\|malonate-decarboxylase-subunit-delta	unknown	unknown	gnl\|CDD\|188283
CP032308.1\|AYA33567.1\|427310_427640_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
CP032308.1\|AYA33564.1\|422203_422401_+\|hypothetical-protein	unknown	unknown	unknown
CP032308.1\|AYA33559.1\|417435_418569_-\|glutathione-dependent-formaldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|176243
CP032308.1\|AYA33566.1\|426432_427299_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
CP032308.1\|AYA33575.1\|437343_438255_+\|acyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|132175
CP032308.1\|AYA33568.1\|428654_429020_+\|DUF1622-domain-containing-protein	unknown	unknown	gnl\|CDD\|377914
CP032308.1\|AYA33570.1\|429542_430970_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|311953
CP032308.1\|AYA33565.1\|422409_426432_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
CP032308.1\|AYA33563.1\|421758_421887_-\|methanol-dehydrogenase	unknown	unknown	unknown
CP032308.1\|AYA33572.1\|434234_435674_-\|HTH-domain-containing-protein	unknown	unknown	gnl\|CDD\|375760
CP032308.1\|AYA33562.1\|420007_421702_-\|oleate-hydratase	unknown	unknown	gnl\|CDD\|237575
CP032308.1\|AYA33573.1\|435817_436180_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225197
CP032308.1\|AYA35484.1\|427629_428292_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
CP032308.1\|AYA33571.1\|431675_434228_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319775
CP032308.1\|AYA33569.1\|429016_429382_+\|DUF1622-domain-containing-protein	unknown	unknown	gnl\|CDD\|377914
CP032308.1\|AYA33576.1\|438261_439908_+\|malonate-decarboxylase-subunit-alpha	unknown	unknown	gnl\|CDD\|379906
CP032308.1\|AYA33560.1\|418858_419719_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP032308.1\|AYA33574.1\|436366_437224_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	5.03447e-40
CP032308.1\|AYA33577.1\|440009_440309_+\|malonate-decarboxylase-subunit-delta	gnl\|CDD\|188283	TIGR03130, malonate_delta, malonate decarboxylase acyl carrier protein. Members of this protein family are the acyl carrier protein, also called the delta subunit, of malonate decarboxylase. This subunit has the same covalently bound prosthetic group, derived from and similar to coenzyme A, as does citrate lyase, although this protein and the acyl carrier protein of citrate lyase do not show significant sequence similarity. Both malonyl and acetyl groups are transferred to the prosthetic group for catalysis.	5.72696e-47
CP032308.1\|AYA33567.1\|427310_427640_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.21799e-43
CP032308.1\|AYA33559.1\|417435_418569_-\|glutathione-dependent-formaldehyde-dehydrogenase	gnl\|CDD\|176243	cd08283, FDH_like_1, Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1. Members identified as glutathione-dependent formaldehyde dehydrogenase(FDH), a member of the zinc-dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. MDH family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes, or ketones. Like many zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), these FDHs form dimers, with 4 zinc ions per dimer. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit.	1.57106e-174
CP032308.1\|AYA33566.1\|426432_427299_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	1.3517e-120
CP032308.1\|AYA33575.1\|437343_438255_+\|acyltransferase-domain-containing-protein	gnl\|CDD\|132175	TIGR03131, malonate_mdcH, malonate decarboxylase, epsilon subunit. Members of this protein family are the epsilon subunit of malonate decarboxylase. This subunit has malonyl-CoA/dephospho-CoA acyltransferase activity. Malonate decarboxylase may be a soluble enzyme, or linked to membrane subunits and active as a sodium pump. The epsilon subunit is closely related to the malonyl CoA-acyl carrier protein (ACP) transacylase family described by TIGR00128, but acts on an ACP subunit of malonate decarboxylase that has an unusual coenzyme A derivative as its prothetic group.	7.81403e-66
CP032308.1\|AYA33568.1\|428654_429020_+\|DUF1622-domain-containing-protein	gnl\|CDD\|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	1.12042e-21
CP032308.1\|AYA33570.1\|429542_430970_-\|DNA-binding-protein	gnl\|CDD\|311953	pfam08280, HTH_Mga, M protein trans-acting positive regulator (MGA) HTH domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions.	0.00286035
CP032308.1\|AYA33565.1\|422409_426432_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
CP032308.1\|AYA33572.1\|434234_435674_-\|HTH-domain-containing-protein	gnl\|CDD\|375760	pfam18333, ssDNA_DBD, Non-canonical single-stranded DNA-binding domain. This domain is found in ThermoDBP, a non-canonical single-stranded DNA-binding protein in Thermoproteales. Single-stranded DNA-binding proteins are needed for DNA metabolism, sequestering and protecting transiently formed ssDNA during DNA replication and recombination, detecting DNA damage and recruiting repair proteins. The outer edge of the ssDNA-binding cleft, formed by this domain, has a strongly positive electrostatic surface potential because of the conserved basic residues R49, K54, R65, R80, R86, R90, K97, and R112.	5.17836e-38
CP032308.1\|AYA33562.1\|420007_421702_-\|oleate-hydratase	gnl\|CDD\|237575	PRK13977, PRK13977, myosin-cross-reactive antigen; Provisional.	0
CP032308.1\|AYA33573.1\|435817_436180_+\|hypothetical-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	2.53951e-18
CP032308.1\|AYA35484.1\|427629_428292_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.01282e-107
CP032308.1\|AYA33571.1\|431675_434228_+\|HAD-family-hydrolase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
CP032308.1\|AYA33569.1\|429016_429382_+\|DUF1622-domain-containing-protein	gnl\|CDD\|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	8.2154e-25
CP032308.1\|AYA33576.1\|438261_439908_+\|malonate-decarboxylase-subunit-alpha	gnl\|CDD\|379906	pfam16957, Mal_decarbox_Al, Malonate decarboxylase, alpha subunit, transporter. Mal_decarbox_Al is a family of Na+-transporting carboxylic acid decarboxylases.	0

>CP032308.1|AYA35484.1|427629_428292_+|type-II-A-CRISPR-associated-protein-Csn2
MNLNFPLLEQPLPLEKATFLIVEDVTVFAKVVKWFYQYSESHELKLFNDKYKELKESDLLIITDVLGFDINSASTLKLIYADLERQLNEKVEVKSMIDKLTATISELIGYELLDHELDLEGDEITVLELFKALGIKIETRSDTIFEKLLELLQVYKYLSKKKLLVLINVCSYLTEEEISEVQDYISLYHMEVLFVEPRSIKGIKQFVLDKDYFLNLENMV
>CP032308.1|AYA33567.1|427310_427640_+|CRISPR-associated-endonuclease-Cas2
MRMILMFDMPTETADERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNPTASQAMLKRLKSNNPKKGFVTLLTVTEKQFARMVYLSGERDTSVANSDKRVIYLGEDEDAES
>CP032308.1|AYA33566.1|426432_427299_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVNTHSKLAYVNNHLIFKNAEKTERLHLSEIDVLLLETTDITITTMLLKRLVDEKILVLFCDDKRLPVAKLLPFYSRHDSSLQLTRQLAWSPEKKGQVWTAIISQKIQNQSNFLQKQLFTEKAESIQELHEGLLEFDPTNREGHAARIYFQTLFGTKFTREENNEINAGLDYGYTLLLSMFAREIVKNGCMTQFGLKHANQFNDFNLASDFMEPFRPVIDEIVYRYRNCEFPVIKRRLFDLFTNKYSYGKKEMFLTNIVSDYTSNVIKVLNNETEGVPQFRI
>CP032308.1|AYA33565.1|422409_426432_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKEYTIGLDIGTNSVGWSVLTDDYRLVSKKMKVAGNTEKSSTKKNFWGVRLFDEGQTAEARRSKRTARRRLARRRQRILELQKIFAPEILKIDEHFFARLNESFLVLDEKKQSRHPVFATIKQEKSYHQTYPTIYHLRQALADSSEKADIRLVYLAMAHLLKYRGHFLIEGELNTENSSVTETFRQFLSTYNQQFSEADDKQTEKLDEAVDCSFVFTEKMSKTKKAETLLKYFPHEKSNGYLSQFIKLMVGNQGNFKNVFGLEEEAKLQFSKETYEEDLEELLEKIGDDYIDLFVQAKNVYDAVLLSEILSDSTKNTRAKLSAGMIRRYDAHKEDLVLLKRFVKENLPKKYRAFFGDNSVNGYAGYIEGHATQEDFYKFVKKELTGIRGSEVFLTKIEQENFLRKQRTFDNGVIPHQIHLTELRAIIANQKKHYPFLKEEQEKLESLLTFKIPYYVGPLAKKQENSPFAWLIRKSEEKIKPWNLPEIVDMEGSAVRFIERMINTDMYMPHNKVLPKNSLLYQKFSIYNELTKVRYQDERGQMNYFSSIEKKEIFHELFEKNRKVTKKDLQEFLYLKYDIKHAELSGIEKAFNASYTTYHDFLTMSENKREMKQWLEDPELASMFEEIIKTLTVFEDREMIKTRLSHHEATLGKHIIKKLTKKHYTGWGRLSKELIQGIRDKQSNKTILDYLINDDDFPHHRNRNFMQLINDDSLSFKKEIKKAQMITDTENLEEIVKELTGSPAIKKGILQSLKIVDEIVGIMGYEPANIVVEMARENQTTGRGLKSSRPRLKALEESLKDFGSQLLKEYPTDNSFLQKDRLYLYYLQNGRDMYTGAPLDIHRLSDYDIDHIIPRSFTTDNSIDNKVLVSSKENRLKKDDVPSEKVVKKMRSFWYDLYSSKLISKRKLDNLTKIKLTEEDKAGFIKRQLVETRQITKHVAGILHHRFNKAEDTNEPIRKVRIITLKSALVSQFRNRFGIYKVREINEYHHAHDAYLNGVVALALLKKYPQLAPEFVYGEYLKFNAHKANKATVKKEFYSNIMKFFESDTPVCDENGEIFWDKSKSIAQVKKVINHHHMNIVKKTEIQKGGFSKETVEPKKDSSKLLPRKNNWDPAKYGGLGSPNVAYTVAFTYEKGKARKRTNALEGITIMEREAFEQSPVLFLKNKGYEQAEIEMKLPKYALFELENGRKRMVASNKEAQKANSFLLPEHLVTLLYHAKQYDEISHKESFDYVNEHHKEFSEVFARVLEFAGKYTLAEKNIEKLEKIYKENQTDDLAKLASSFVNLMQFNAMGAPADFKFFDVTIPRKRYTSLTEIWQSTIIHQSITGLYETRIRMGK
>CP032308.1|AYA33564.1|422203_422401_+|hypothetical-protein
MILKSKAQKKRREQRCFKKADDGQSLILTCYIDLNATNIFIIAKITAFTIGVFVFSIMMSCWMKG
>CP032308.1|AYA33563.1|421758_421887_-|methanol-dehydrogenase
MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI
>CP032308.1|AYA33562.1|420007_421702_-|oleate-hydratase
MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSNDGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTAEEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDNITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVNRTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQEEEHVTVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGNPDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITSLGQKDVNMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSKVDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGEFVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE
>CP032308.1|AYA33561.1|419743_419935_-|hypothetical-protein
MHKFGLIPRNWLLNTVYQEVVSLPFSSESQGTISKNSFLCFMNIVTCDRGVGRGTPFIHNKRL
>CP032308.1|AYA33560.1|418858_419719_+|hypothetical-protein
MKQIQNKWNKRIIVMISSVCLFCLTVMLCLISTLANQHFMLEQNMQSDYAKKVAAEINQEIQSYHYEIGAPAEALEKIVSEELVQKNIELFIRNRYEKEPVELIGEKEVEEKLQEIINTYKQEEAEDDPFASEENNLLIYMTSGIFRRGIQSIYLMSFIDQILTIRERMVSFLPVISSILLVLLSGVFYLYRMSWKKVLWSFAVVIGGAGFQLLSLSVSLHLYDMTSQLDIRTQALQHLLDTYILSFIQFFSVVAIIEVVIAAGLWWIGKRVNTEKMVFSKRNEYK
>CP032308.1|AYA33559.1|417435_418569_-|glutathione-dependent-formaldehyde-dehydrogenase
MKAVTWQGKQKMEIRNVDDPRILEPTDAIIRITATAICGSDLHLYHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMESQCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNNLPDEKVLFLSDILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKAANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGTISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYEMIAEGLFDPTQIITHSLPLEEAAQAYEIFDKKEDKNIKVVLKP
>CP032308.1|AYA33568.1|428654_429020_+|DUF1622-domain-containing-protein
MFNTQLIGYLEWIIAILNICSIGILIAGIVLVLFKLFDWSHVKKNYAERNARNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVISYFLNQEIEDKEKQRRGEVG
>CP032308.1|AYA33569.1|429016_429382_+|DUF1622-domain-containing-protein
MTTELMQFLLPYFEKLVLGLDIFAICLLIWGVCLSIKDFLKYLFVHTEAKNDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIRTIISYFLNKEIGPVDVPNK
>CP032308.1|AYA33570.1|429542_430970_-|DNA-binding-protein
MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSYLLHVCKTTLLNDINNIKKEFEEQIVYTHREKDCYTLYFSEHIPRCKIMQQLTQNSLFLKTCLLYLEENEPDYLQLTECEFISVSKAYSLKKQVLAYFHDCGIEIDRYSPRFTEMERRLLLLNVAYRLGSFKSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQLCTVTIDPTFIEEIKKRPIYNYVESAWETTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDFQQLHQVFIDNTPEIKELVAIFETHFHQELFGNQPFERALIHLMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQTLFSSWAKRLPYDLRFNPNCMRAFVIELSGILRLTKERLTIYIVTNSDVHYLIYREALEAVTTFDFQVAPTIYASMSDIKKYAQQSSNRVLCERTLYTPEAVQYENIIPISINTIERAIVSAVQNK
>CP032308.1|AYA33571.1|431675_434228_+|HAD-family-hydrolase
MNWYKLTVEDTLKNHQTSTEGLSQEERQKRLTDQGYNEIEARQQTKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEESLNGLKQLMGQEAIVLSNGMQVKIPAKELVKGDVIVLRAGYVVPADVRLIEVHDLLVEESILTGESEASEKNHSVLAAEESIGDQKNMAFSGTLVQSGSAVGVVVETGNTTEIGKINQALQSVEQQTTPLIKKINRLNKQIFQGILCLILFLVVFTTFRYGMDWHILLSAMIALVVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNEMTVVDVAAKEETRVLSIMKNCQELKTKEEQKIENLSGNPTELALIRHTETANLPLKKIEAKIPFSSEYKYMATMHTEEKGTVIYVKGAPEVLLAKSTLSYSEQEAWGQTATAFAKKGQRVLGFAYKKVDSKQELTHESLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKMITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSEEELTRQVPKVDVFARTTPEHKLRIVKALQKNGEIVGMTGDGVNDAPALKRADIGIAMGIKGSEVSKQAADMVLGDDNFHTIAKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALILNRPLPLSPVQILWVNMVTTITLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVALLIMVPAYLLAMQFEGQSLQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKSLFLSLGILALLQGMVIFLPIGQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREFSR
>CP032308.1|AYA33572.1|434234_435674_-|HTH-domain-containing-protein
MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTERTIFSDLQSIRSHLPEGWDIFSDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLFTKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFYHRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKANCRLDSSIHINSTLSSLYDSALKKLYLKEGIYLKDTELSFASFCFLESWNYNNNYGQEIARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLVLKYHESPILIEPLERQYHRFLETYDQQYAHLYQQKENLLNDLKKEMEINEPNYFLQLLSLLIQQTIFSIKPNLFNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDSLDIPIVYISSIPTKNELNRLTELTFKTFL
>CP032308.1|AYA33573.1|435817_436180_+|hypothetical-protein
MLTEKELIDHIDETYNLSPEYIFKKFPDYCVFSHQKSKKWFGVLMSVPEEKIYDDASDHRIIDILDLKVDPELGGILRGKEVYFPAYHMNKEHWISVDLRKIEKLDELAGLIDESFKSTQ
>CP032308.1|AYA33574.1|436366_437224_-|LysR-family-transcriptional-regulator
MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELGVPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASVSIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAIPKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATLRSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAKTMREFYLGK
>CP032308.1|AYA33575.1|437343_438255_+|acyltransferase-domain-containing-protein
MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENYQDTVFIQLALLTKAVFYLDEMEKNGIQPDIVAGHSIGAFCAAVACRSLTFENAAELVYHRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSIEGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLFDARCLYIKNTDGRATQEAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKFGVDKGIRTINLDQHGIDDATFLYQKWR
>CP032308.1|AYA33576.1|438261_439908_+|malonate-decarboxylase-subunit-alpha
MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLIAPGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKIDFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNLYTGFNTEETPTIVEAAAFKDGIVIVQVNEVVDKLPRVDIPGDWVDVVVKADQPYQLEALFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLKGKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSNRTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPAWQSLRNNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSEDTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKKSLDRLRDVGIVKLPEDLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS
>CP032308.1|AYA33577.1|440009_440309_+|malonate-decarboxylase-subunit-delta
MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKKESTVKICTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK

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Crispr_ID: CP032308_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP032308_4

2293637-2293772

Orphan

Consensus_repeat	Method
CTTTGCTCAACCAGTATTGTTCATCATCTATTCTCTTCGTTCATAGTGATTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP032308_4

>merge|CP032308|4|2293637-2293772|CRISPRCasFinder
CTTTGCTCAACCAGTATTGTTCATCATCTATTCTCTTCGTTCATAGTGATTCTACTCGCTTTGCTCGAAAGGAAACTCCTTTCGCTTTGCTCAACCAGTATTGTTCATCATCTATTCTCTTCGTTCATAGTGATTC

>CP032308|4|3|2293637-2293772|CRISPRCasFinder
CTTTGCTCAACCAGTATTGTTCATCATCTATTCTCTTCGTTCATAGTGATTC	TACTCGCTTTGCTCGAAAGGAAACTCCTTTCG
CTTTGCTCAACCAGTATTGTTCATCATCTATTCTCTTCGTTCATAGTGATTC

Protein	Signature genes	Signature genes Name	Protein_function
CP032308.1\|AYA35228.1\|2292639_2293008_-\|50S-ribosomal-protein-L7/L12	unknown	unknown	gnl\|CDD\|234671
CP032308.1\|AYA35235.1\|2298370_2299252_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|283645
CP032308.1\|AYA35220.1\|2280908_2282696_+\|beta-galactosidase	unknown	unknown	gnl\|CDD\|366567
CP032308.1\|AYA35232.1\|2295531_2296200_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	unknown	unknown	gnl\|CDD\|224674
CP032308.1\|AYA35230.1\|2293973_2294663_-\|50S-ribosomal-protein-L1	unknown	unknown	gnl\|CDD\|180071
CP032308.1\|AYA35224.1\|2288048_2288750_-\|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|238693
CP032308.1\|AYA35231.1\|2294766_2295189_-\|50S-ribosomal-protein-L11	unknown	unknown	gnl\|CDD\|234661
CP032308.1\|AYA35233.1\|2296212_2297085_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|129801
CP032308.1\|AYA35227.1\|2291843_2292533_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
CP032308.1\|AYA35222.1\|2285758_2286898_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
CP032308.1\|AYA35234.1\|2297178_2298279_-\|lactate-oxidase	unknown	unknown	gnl\|CDD\|240088
CP032308.1\|AYA35225.1\|2288983_2290516_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223562
CP032308.1\|AYA35237.1\|2299974_2300145_-\|preprotein-translocase-subunit-SecE	unknown	unknown	gnl\|CDD\|376355
CP032308.1\|AYA35236.1\|2299328_2299874_-\|transcription-termination/antitermination-protein-NusG	unknown	unknown	gnl\|CDD\|180161
CP032308.1\|AYA35239.1\|2300479_2301124_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341358
CP032308.1\|AYA35238.1\|2300165_2300318_-\|50S-ribosomal-protein-L33	unknown	unknown	gnl\|CDD\|234783
CP032308.1\|AYA35221.1\|2283641_2285378_-\|DUF2264-domain-containing-protein	unknown	unknown	gnl\|CDD\|378358
CP032308.1\|AYA35226.1\|2290571_2291762_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340882
CP032308.1\|AYA35229.1\|2293060_2293564_-\|50S-ribosomal-protein-L10	unknown	unknown	gnl\|CDD\|234632
CP032308.1\|AYA35223.1\|2287076_2287790_-\|MgtC/SapB-family-protein	unknown	unknown	gnl\|CDD\|224204

Protein	Function_ID	Function_description	E-value
CP032308.1\|AYA35228.1\|2292639_2293008_-\|50S-ribosomal-protein-L7/L12	gnl\|CDD\|234671	PRK00157, rplL, 50S ribosomal protein L7/L12; Reviewed.	4.29798e-45
CP032308.1\|AYA35235.1\|2298370_2299252_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|283645	pfam06028, DUF915, Alpha/beta hydrolase of unknown function (DUF915). This family consists of several bacterial proteins of unknown function. Members of this family have an alpha/beta hydrolase fold.	3.2958e-76
CP032308.1\|AYA35220.1\|2280908_2282696_+\|beta-galactosidase	gnl\|CDD\|366567	pfam01301, Glyco_hydro_35, Glycosyl hydrolases family 35.	4.94058e-160
CP032308.1\|AYA35232.1\|2295531_2296200_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	gnl\|CDD\|224674	COG1760, SdaA, L-serine deaminase [Amino acid transport and metabolism].	4.37283e-73
CP032308.1\|AYA35230.1\|2293973_2294663_-\|50S-ribosomal-protein-L1	gnl\|CDD\|180071	PRK05424, rplA, 50S ribosomal protein L1; Validated.	2.1815e-146
CP032308.1\|AYA35224.1\|2288048_2288750_-\|glucosamine-6-phosphate-deaminase	gnl\|CDD\|238693	cd01399, GlcN6P_deaminase, GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.	8.8122e-119
CP032308.1\|AYA35231.1\|2294766_2295189_-\|50S-ribosomal-protein-L11	gnl\|CDD\|234661	PRK00140, rplK, 50S ribosomal protein L11; Validated.	9.059e-96
CP032308.1\|AYA35233.1\|2296212_2297085_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	5.46875e-102
CP032308.1\|AYA35227.1\|2291843_2292533_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	4.13975e-20
CP032308.1\|AYA35222.1\|2285758_2286898_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	2.74684e-61
CP032308.1\|AYA35234.1\|2297178_2298279_-\|lactate-oxidase	gnl\|CDD\|240088	cd04737, LOX_like_FMN, L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate dehydrogenase (MDH), and long chain hydroxyacid oxidase (LCHAO).	0
CP032308.1\|AYA35225.1\|2288983_2290516_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	3.40093e-169
CP032308.1\|AYA35237.1\|2299974_2300145_-\|preprotein-translocase-subunit-SecE	gnl\|CDD\|376355	pfam00584, SecE, SecE/Sec61-gamma subunits of protein translocation complex. SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.	1.6158e-13
CP032308.1\|AYA35236.1\|2299328_2299874_-\|transcription-termination/antitermination-protein-NusG	gnl\|CDD\|180161	PRK05609, nusG, transcription antitermination protein NusG; Validated.	1.97252e-86
CP032308.1\|AYA35239.1\|2300479_2301124_+\|CBS-domain-containing-protein	gnl\|CDD\|341358	cd02205, CBS_pair_SF, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains superfamily. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	4.83595e-14
CP032308.1\|AYA35238.1\|2300165_2300318_-\|50S-ribosomal-protein-L33	gnl\|CDD\|234783	PRK00504, rpmG, 50S ribosomal protein L33; Validated.	3.12722e-17
CP032308.1\|AYA35221.1\|2283641_2285378_-\|DUF2264-domain-containing-protein	gnl\|CDD\|378358	pfam10022, DUF2264, Uncharacterized protein conserved in bacteria (DUF2264). Members of this family of hypothetical bacterial proteins have no known function.	3.33288e-140
CP032308.1\|AYA35226.1\|2290571_2291762_-\|MFS-transporter	gnl\|CDD\|340882	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily. This family is composed of purine efflux pumps such as Escherichia coli NepI and Bacillus subtilis PbuE, sugar efflux transporters such as Corynebacterium glutamicum arabinose efflux permease, multidrug resistance (MDR) transporters such as Streptomyces lividans chloramphenicol resistance protein (CmlR), and similar proteins. NepI and PbuE are involved in the efflux of purine ribonucleosides such as guanosine, adenosine and inosine, as well as purine bases like guanine, adenine, and hypoxanthine, and purine base analogs. They play a role in the maintenance of cellular purine base pools, as well as in protecting the cells and conferring resistance against toxic purine base analogs such as 6-mercaptopurine. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The NepI-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.72795e-69
CP032308.1\|AYA35229.1\|2293060_2293564_-\|50S-ribosomal-protein-L10	gnl\|CDD\|234632	PRK00099, rplJ, 50S ribosomal protein L10; Reviewed.	3.03735e-67
CP032308.1\|AYA35223.1\|2287076_2287790_-\|MgtC/SapB-family-protein	gnl\|CDD\|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	1.06034e-48

>CP032308.1|AYA35229.1|2293060_2293564_-|50S-ribosomal-protein-L10
MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRKQLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAKEAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVADKEDGDAA
>CP032308.1|AYA35228.1|2292639_2293008_-|50S-ribosomal-protein-L7/L12
MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAAGGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSKEEADELKAKLEEVGASVTVK
>CP032308.1|AYA35227.1|2291843_2292533_-|TVP38/TMEM64-family-protein
MKKKKIRLILITLGIVLILMVGYRLYLEYQTDIQLFLNPRASKEELLAHIRSHGFSASLLLIVLTAVMCAVPGIPTSVIGVIAGLSFGPFIGAGINVLGNALGNISAVFLMHRLKFLDKKTEKNHWVQSIRQMRHPKIGVMLGYMIPVIPSSMVNFAADAMKLPLQQIVMSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKDRKKKQGKQRQK
>CP032308.1|AYA35226.1|2290571_2291762_-|MFS-transporter
MESKEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSVSTSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAISLLAAFFAPSFALFACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVASLFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTSVSYLDSLKSLPHLVASQRLLREAAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADSYSERKIVYMGLVMQTISFIALLVGGSHLVILLLAIILLDVGNQFGQVANQTRVQGLGEAASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQFVVFREKKEN
>CP032308.1|AYA35225.1|2288983_2290516_+|ABC-transporter-ATP-binding-protein
MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKSTLIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLSIEEFLKTAYAKEYEKEEKIAFLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNLSGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEFLDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKYKAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRPLLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDLYWGNPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQLTMNQGNLLILDEPTNHIDQETKESLQDGIRKFPGTVIIVSHEQEFYQDLVQRVIEIEPK
>CP032308.1|AYA35224.1|2288048_2288750_-|glucosamine-6-phosphate-deaminase
MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYKEMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDLEAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRFFDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNHDNVVVIIDEEAASKL
>CP032308.1|AYA35223.1|2287076_2287790_-|MgtC/SapB-family-protein
MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILVCMGACIIALIQVEIASGALRDALAYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVTKQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLEIQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVIEELSVHKNITKLHLVSIAQ
>CP032308.1|AYA35222.1|2285758_2286898_-|AI-2E-family-transporter
MQSRFKQSKLFFWTVELVLTIVGVYFILQMPNIFSPILKMLSAIFLPLLVAGFIYYMFDPIVVFLEKHRIPRVLGFLLTFLVVIILVVLAVMNVVPQLVEQTIQLTQSLPIYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASVTKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETLSAYISSTILDALIIGVMSFLAMRIFNQPYSLLLAVICGITNIIPYVGPFIGAVPAIIVGLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILGMLICIPVYAVIKTIILNIRKIYLLRKMEHVSEKLDSPKLLEETSE
>CP032308.1|AYA35221.1|2283641_2285378_-|DUF2264-domain-containing-protein
MNQLKQNLFLTRRDFEEALEEIILPLKQELFNSEKPGVRLGSSGAVYDEKRAEMEAFIRPLWGLAPYWMNHETKDELKDVYRKKILKGMNPKDSFYWGDINDYDQYIVEMAALSLNLLLNRNYFFDELSGTSKQQLIHWLKQALDKKIPKNNWTFFKILIRIALKHCGESLDKEKMEAELRFIDTMYVGKGWYIDGKSSQKDYYVPFAFHYYGLIFAKLMKDDFPEWSEKFIYRAKEFTKDYIYYFDSDGEALPYGRSLIYRFAQGAFFSALIFAEVEAIPWGQIKTLLSNHMKQWMTHDIFTYDGRLSIGYHYENLVMAEGYNAPGSPYWALKVFLLLATKKEHPYWEAKPEPVNTKEKRLIDNGNMLLCQAKEGKHVLGYPHGLMIDGQAHAPAKYSKFVYSTKFGFSVPKAGITYEEGAFDNTLALSRDGEYFRTKKKVRSSEATETFVMYEWQPFQEVLIQTEIYPFGEWHVRFHEIYTTIPLEIREGGFSLLVKEPEITLSKDCAKIKETHVSQIIAIEGYEEAGIQVLEPNTSVFFPRTNLPYLKKKIEPGTHRFICLVGGIINGGEKNDPN
>CP032308.1|AYA35220.1|2280908_2282696_+|beta-galactosidase
MQTFKIKDEFLVDGIPTKIISGAIHYFRIPPSQWEHSLYNLKALGANTVETYIPWNLHEPQEGSFDFSGFKNVVRFVKIAQELDLMVILRPCAYICAEWEFGGLPAWLLKEPNIRVRSTDPRFMEKLKNYYQVLLPKLAPLQITQGGPVIMMQLENEYGSYGMEKSYLRQTKELMLAHSIDVPLFTSDGAWLEVLDAGTLIDEDIFVTGNFGSHSKENAQVLKEFMQNHQKNWPIMCMEYWDGWFNRWGEPIITRDPEELATEVKEMLEIGSLNLYMFHGGTNFGFYNGCSARGNTDLPQITSYDYDALLNEAGQPTEKYYAVQRVIKEVCPSVWQAEPRTKTLKNLGTYPVNRSVSLFHIKEQICEEIKTDYPLTMEQASNGYGYLLYSLTLKNYGHKNKLRLIETNDRAQIYIDGKYDQTQTQETLGDEMMIEGQKNQPTIALDVLVENLGRVNYGAKLNSPSQSKGIRNGVMQDIHFHLGYRHYPLTFEQAQLDKIDYSAGKDPSQPSFYQFEFDLAEEADAYIDCSLYGKGIVIVNGFNLGRYWNHGPVLSLYCPKDVLKKGRNEVVIFETEGISIDTLIFSDQPIKKDLS
>CP032308.1|AYA35230.1|2293973_2294663_-|50S-ribosomal-protein-L1
MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEVAYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQKIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGKVTYRVDKAGNIHVPIGKVSFDDEKLVENFATIHDVLLKAKPSAAKGQYMKNVTITTTFGPGIHVDQASF
>CP032308.1|AYA35231.1|2294766_2295189_-|50S-ribosomal-protein-L11
MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSSDQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE
>CP032308.1|AYA35232.1|2295531_2296200_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta
MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPDSVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSEKAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVPGMIAKVTGILSETNTNIGTMTVTRESKGESAIMIIEVDNPQVEETVRRLKHLPNIDSVNYFD
>CP032308.1|AYA35233.1|2296212_2297085_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MFLSIEELVDQAKAYSSVAELMIAVEMEMSGRSRSQIIAIMEKNLSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVNAKMGLICATPTAGSAGVVPGVLMAVRDRLGLSHEQQLEFLFTAGAFGLVIANNASISGAEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPCVKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTPTAKRLTEEILNKRS
>CP032308.1|AYA35234.1|2297178_2298279_-|lactate-oxidase
MTYHTSNEEHPIDIVNIASLEGRVKERMEAGAFGYIRGGSEDEWTMKENTTSFNAKKIMPRILRGIDSADLHTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAADAAPGAPQFFQLYMSKDDGFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFPLPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITNLPVIVKGIQSPEDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEHVFKALASGADLVAIGRPIIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKSIDEVKNTKLMD
>CP032308.1|AYA35235.1|2298370_2299252_-|alpha/beta-fold-hydrolase
MTNRIKNVCKHAATAALVLISLFAISGCQTTKTTAVSDKEKTVESSKVIEKTTIPTLFFHGYSGTENSFKGMLQRLEKNQKAVKELVLIVEADGQIQAEGDLSGKADNPMVQVLFADNKNNEWNQAEWIKSCLLYLKENYSIDKVNIVGHSMGGVSALRYLGTYGQDTSLPQVQTFTAIGAPFNDFVDDSGQSLTEELAMGPAVVSSRYQDYQQIIGNMPTTTRFFLIAGQLDEADLSDGTVPLNSALAVYALLKQHGNEVEEKIVKGENAAHSMLHENQEVDQLVSRFVWNE
>CP032308.1|AYA35236.1|2299328_2299874_-|transcription-termination/antitermination-protein-NusG
MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVPEEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPAPLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVNIDMFGRETSTELDFDQVDKID
>CP032308.1|AYA35237.1|2299974_2300145_-|preprotein-translocase-subunit-SecE
MKFLKSVKDEIKQVTWPNRKQLRKDTLVVIETSILFGLMFYVMDTAIQSLFGWILK
>CP032308.1|AYA35238.1|2300165_2300318_-|50S-ribosomal-protein-L33
MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYTLHKETK
>CP032308.1|AYA35239.1|2300479_2301124_+|CBS-domain-containing-protein
MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSGNIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAVLDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKYSSIASCITLDIEKDEYIRRTLITLPANTEPKVCETIINHIEKKNYKVVEIENLQNQEA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP032308_1	1.3\|322282\|35\|CP032308\|CRT	322282-322316	35	AB711120	Bacillus phage PM1 DNA, complete genome	15177-15211	9	0.743
CP032308_1	1.5\|322420\|35\|CP032308\|CRT	322420-322454	35	NC_011413	Escherichia coli SE11 plasmid pSE11-2, complete sequence	3807-3841	9	0.743
CP032308_1	1.1\|322144\|35\|CP032308\|CRT	322144-322178	35	NC_011413	Escherichia coli SE11 plasmid pSE11-2, complete sequence	3807-3841	10	0.714
CP032308_1	1.2\|322213\|35\|CP032308\|CRT	322213-322247	35	NC_011413	Escherichia coli SE11 plasmid pSE11-2, complete sequence	3807-3841	10	0.714
CP032308_1	1.6\|322489\|35\|CP032308\|CRT	322489-322523	35	CP031730	Stenotrophomonas rhizophila strain GA1 plasmid unnamed1, complete sequence	136113-136147	10	0.714

1. spacer 1.3|322282|35|CP032308|CRT matches to AB711120 (Bacillus phage PM1 DNA, complete genome) position: , mismatch: 9, identity: 0.743

ttctcctgtaaattcagaataattaaaagcaccat	CRISPR spacer
atttcctgtaaattcataataattaaaaccgttta	Protospacer
 *.************* *********** *...

2. spacer 1.5|322420|35|CP032308|CRT matches to NC_011413 (Escherichia coli SE11 plasmid pSE11-2, complete sequence) position: , mismatch: 9, identity: 0.743

acttcctgtaaatttagaaccactgaaagcactat	CRISPR spacer
acttactgtaaatttagaaccattggatatatggt	Protospacer
**** *****************.**.* ..*. .*

3. spacer 1.1|322144|35|CP032308|CRT matches to NC_011413 (Escherichia coli SE11 plasmid pSE11-2, complete sequence) position: , mismatch: 10, identity: 0.714

acttcctgtaaatttagaaccactgaaagcactac	CRISPR spacer
acttactgtaaatttagaaccattggatatatggt	Protospacer
**** *****************.**.* ..*. ..

4. spacer 1.2|322213|35|CP032308|CRT matches to NC_011413 (Escherichia coli SE11 plasmid pSE11-2, complete sequence) position: , mismatch: 10, identity: 0.714

acttcctgtaaatttagaaccactgaaagcagaag	CRISPR spacer
acttactgtaaatttagaaccattggatatatggt	Protospacer
**** *****************.**.* ..* ..

5. spacer 1.6|322489|35|CP032308|CRT matches to CP031730 (Stenotrophomonas rhizophila strain GA1 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.714

ttctcctgaaaaattagggtattcaaaagcatgag	CRISPR spacer
tgctcttgaaaaattagggttttcaaatctttcta	Protospacer
* ***.************** ******  . *  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

316220 : 368425

Bacillus_phage(16.67%)

integrase,transposase

attL 315947:316006|attR 336919:337106

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
315947:316006	attL	NA	NA	NA	NA
AYA33471.1\|316220_317387_-\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	3.1e-59	36.3
AYA33472.1\|317576_318062_+	hypothetical protein	NA	NA	NA	NA
AYA33473.1\|318051_318678_+	hypothetical protein	NA	NA	NA	NA
AYA33474.1\|318695_319616_+	hypothetical protein	NA	NA	NA	NA
AYA33475.1\|319845_320421_+\|integrase	site-specific integrase	A0A1B0T6D2	Bacillus_phage	8.4e-26	39.4
AYA33476.1\|320437_321352_-	hypothetical protein	NA	NA	NA	NA
AYA33477.1\|321921_323112_-	leucine-rich repeat domain-containing protein	NA	NA	NA	NA
AYA33478.1\|323452_324022_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	2.8e-21	39.0
AYA33479.1\|324339_325758_+	hypothetical protein	NA	NA	NA	NA
AYA33480.1\|325750_325987_+	hypothetical protein	NA	NA	NA	NA
AYA33481.1\|326452_326722_+	hypothetical protein	NA	NA	NA	NA
AYA33482.1\|326702_328559_+	hypothetical protein	NA	NA	NA	NA
AYA33483.1\|329537_329705_-	peptidase	NA	NA	NA	NA
AYA33484.1\|330353_330533_+	hypothetical protein	NA	NA	NA	NA
AYA33485.1\|330771_330999_+	hypothetical protein	NA	NA	NA	NA
AYA33486.1\|331118_332312_+	DNA methyltransferase	A0A1B0XVT8	Campylobacter_phage	3.0e-25	32.9
AYA33487.1\|332308_333478_+	DUF262 domain-containing protein	NA	NA	NA	NA
AYA33488.1\|333743_335357_+	DUF2813 domain-containing protein	NA	NA	NA	NA
AYA33489.1\|335335_336454_+	hypothetical protein	NA	NA	NA	NA
AYA33490.1\|336455_336740_+	hypothetical protein	NA	NA	NA	NA
AYA33491.1\|337366_339187_+	hypothetical protein	NA	NA	NA	NA
336919:337106	attR	NA	NA	NA	NA
AYA33492.1\|339336_340763_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	2.3e-48	40.6
AYA33493.1\|341031_342369_+	citrate transporter	NA	NA	NA	NA
AYA33494.1\|342416_344546_+	hydantoinase/oxoprolinase family protein	NA	NA	NA	NA
AYA33495.1\|344520_345210_+	hypothetical protein	NA	NA	NA	NA
AYA33496.1\|345603_346290_-	GntR family transcriptional regulator	NA	NA	NA	NA
AYA33497.1\|346668_347109_-	acyl-CoA thioesterase	NA	NA	NA	NA
AYA33498.1\|347112_347958_-	NAD(P)H-hydrate dehydratase	NA	NA	NA	NA
AYA33499.1\|348106_349525_+	dipeptidase PepV	NA	NA	NA	NA
AYA33500.1\|349580_350528_-	glycosyltransferase	NA	NA	NA	NA
AYA33501.1\|350749_351100_-	peptidase	NA	NA	NA	NA
AYA33502.1\|351299_352379_+	glutamyl aminopeptidase	NA	NA	NA	NA
AYA33503.1\|352521_352842_+	thioredoxin	NA	NA	NA	NA
AYA33504.1\|352863_353328_+	universal stress protein	NA	NA	NA	NA
AYA33505.1\|353523_354129_+	DUF4479 domain-containing protein	NA	NA	NA	NA
AYA33506.1\|354167_355457_-	PDZ domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	5.7e-22	30.2
AYA33507.1\|355884_356364_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
AYA33508.1\|356413_357262_+	hypothetical protein	G9IA57	Pseudomonas_phage	5.8e-15	33.3
AYA35482.1\|357532_357916_-	hypothetical protein	NA	NA	NA	NA
AYA33509.1\|358142_359315_+\|transposase	IS256 family transposase IS1542	A0A0N9STL0	Staphylococcus_phage	1.3e-121	88.8
AYA33510.1\|360257_361217_-\|transposase	IS30 family transposase	H7BW61	unidentified_phage	2.2e-10	26.8
AYA33511.1\|361820_362192_+	hypothetical protein	NA	NA	NA	NA
AYA33512.1\|362184_363600_+	peptidase	A0A1B2AQ05	Phage_Wrath	3.3e-23	24.3
AYA33513.1\|364030_364270_+	hypothetical protein	NA	NA	NA	NA
AYA33514.1\|364285_365659_+	recombinase family protein	A0A2P1JU08	Anoxybacillus_phage	1.8e-13	21.7
AYA33515.1\|365662_367300_+	recombinase family protein	A0A2P1JU08	Anoxybacillus_phage	4.8e-42	28.1
AYA33516.1\|367516_368425_+\|transposase	IS982 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

643394 : 703887

Streptococcus_phage(18.75%)

transposase,lysis,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYA33758.1\|643394_644057_-\|lysis	5-bromo-4-chloroindolyl phosphate hydrolysis protein	NA	NA	NA	NA
AYA35492.1\|644284_644848_+	NUDIX hydrolase	NA	NA	NA	NA
AYA33759.1\|644860_645145_+	hypothetical protein	NA	NA	NA	NA
AYA33760.1\|645163_645856_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
AYA33761.1\|645867_646413_+	cysteine hydrolase	G3MA16	Bacillus_virus	4.4e-24	37.4
AYA33762.1\|646678_649948_+	DUF1565 domain-containing protein	NA	NA	NA	NA
AYA33763.1\|650367_652275_-	M13 family peptidase	E3T4I7	Cafeteria_roenbergensis_virus	8.8e-80	30.8
AYA33764.1\|652406_653282_+	dihydrolipoamide dehydrogenase	NA	NA	NA	NA
AYA33765.1\|653361_654336_+	ribose-phosphate diphosphokinase	A0A1V0SHF7	Hokovirus	3.5e-40	32.2
AYA35493.1\|654768_655905_+	cysteine desulfurase	NA	NA	NA	NA
AYA33766.1\|656041_656386_+	cysteine desulfurase	NA	NA	NA	NA
AYA33767.1\|656494_657277_-	hypothetical protein	NA	NA	NA	NA
AYA33768.1\|658874_659462_+	metallophosphatase	A0A288TXW7	Enterococcus_phage	1.3e-34	42.0
AYA35494.1\|659731_660157_-	hypothetical protein	NA	NA	NA	NA
AYA33769.1\|660848_661808_+\|transposase	IS30 family transposase	H7BW61	unidentified_phage	2.2e-10	26.8
AYA33770.1\|663148_663400_+	hypothetical protein	NA	NA	NA	NA
AYA33771.1\|663673_663931_+	hypothetical protein	NA	NA	NA	NA
AYA33772.1\|663985_664246_+	hypothetical protein	NA	NA	NA	NA
AYA33773.1\|664588_664855_+	hypothetical protein	NA	NA	NA	NA
AYA33774.1\|664895_665513_+	hypothetical protein	NA	NA	NA	NA
AYA33775.1\|665601_666207_+	hypothetical protein	NA	NA	NA	NA
AYA33776.1\|666413_667535_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
AYA33777.1\|667778_669200_+	arginine-ornithine antiporter	NA	NA	NA	NA
AYA33778.1\|669213_670332_+	aminotransferase	NA	NA	NA	NA
AYA33779.1\|670391_671684_-	MFS transporter	NA	NA	NA	NA
AYA35495.1\|671833_672394_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AYA33780.1\|672522_672900_+	DUF1033 family protein	NA	NA	NA	NA
AYA33781.1\|672832_674905_+	DNA topoisomerase III	NA	NA	NA	NA
AYA33782.1\|675240_676188_-	glycosyltransferase	V5USA4	Oenococcus_phage	5.0e-84	51.3
AYA33783.1\|676433_676898_+	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	4.0e-18	37.8
AYA33784.1\|676960_678004_-	putative sulfate exporter family transporter	NA	NA	NA	NA
AYA35496.1\|678104_678308_+	hypothetical protein	NA	NA	NA	NA
AYA33785.1\|678377_679346_-	C4-dicarboxylate ABC transporter	NA	NA	NA	NA
AYA33786.1\|679576_680419_+	LysR family transcriptional regulator	NA	NA	NA	NA
AYA33787.1\|680430_680628_+	hypothetical protein	NA	NA	NA	NA
AYA33788.1\|680612_681800_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
AYA33789.1\|681805_682162_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	9.1e-23	43.2
AYA33790.1\|682163_682502_+	glycine cleavage system protein H	NA	NA	NA	NA
AYA35497.1\|682896_683931_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	4.2e-28	35.1
AYA33791.1\|683923_684610_+	ABC transporter permease	NA	NA	NA	NA
AYA33792.1\|684633_685482_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AYA33793.1\|685678_686452_+	Fe-S cluster assembly ATPase SufC	A0A2R8FG22	Brazilian_cedratvirus	2.1e-08	28.8
AYA33794.1\|686464_687751_+	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
AYA33795.1\|687747_688983_+	cysteine desulfurase	Q2XUY6	environmental_halophage	1.1e-112	47.5
AYA33796.1\|688969_689440_+	SUF system NifU family Fe-S cluster assembly protein	NA	NA	NA	NA
AYA33797.1\|689444_690836_+	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
AYA33798.1\|690944_692000_-	LysR family transcriptional regulator	NA	NA	NA	NA
AYA33799.1\|692055_692415_+	RidA family protein	NA	NA	NA	NA
AYA35498.1\|692460_693609_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
AYA33800.1\|693615_694362_+	hypothetical protein	NA	NA	NA	NA
AYA33801.1\|694390_695569_-\|transposase	IS256-like element ISEf1 family transposase	NA	NA	NA	NA
AYA33802.1\|695726_696362_+	hypothetical protein	NA	NA	NA	NA
AYA33803.1\|696431_696671_+	hypothetical protein	NA	NA	NA	NA
AYA33804.1\|696718_697403_+\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	2.0e-127	99.6
AYA33805.1\|697630_698242_+	recombinase family protein	M9Q1K0	Clostridium_phage	4.0e-18	41.3
AYA33806.1\|698275_700300_+	hypothetical protein	NA	NA	NA	NA
AYA33807.1\|700312_700993_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	2.3e-107	83.5
AYA33808.1\|701300_701537_+	XRE family transcriptional regulator	A0A097PBE6	Streptococcus_pyogenes_phage	7.4e-13	52.1
AYA33809.1\|701772_703887_+\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	5.3e-118	39.3

DBSCAN-SWA_3

1309926 : 1363066

unidentified_phage(27.27%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYA34342.1\|1309926_1310886_+\|transposase	IS30-like element IS6770 family transposase	NA	NA	NA	NA
AYA34343.1\|1311200_1311482_+	hypothetical protein	NA	NA	NA	NA
AYA34344.1\|1311662_1311965_-	hypothetical protein	NA	NA	NA	NA
AYA34345.1\|1313071_1313269_+	cold-shock protein	Q9AZD3	Lactococcus_phage	2.3e-23	78.5
AYA34346.1\|1313556_1313910_+	ArsR family transcriptional regulator	NA	NA	NA	NA
AYA34347.1\|1314521_1315445_+	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
AYA34348.1\|1315525_1315918_-	VOC family protein	NA	NA	NA	NA
AYA34349.1\|1316027_1316819_-	hypothetical protein	NA	NA	NA	NA
AYA35515.1\|1317562_1317865_-	hypothetical protein	NA	NA	NA	NA
AYA34350.1\|1318046_1318460_-	Hsp20/alpha crystallin family protein	A0A1B2LRT2	Wolbachia_phage	2.1e-07	30.8
AYA34351.1\|1318651_1319272_+	hypothetical protein	NA	NA	NA	NA
AYA34352.1\|1319369_1319855_-	hypothetical protein	NA	NA	NA	NA
AYA34353.1\|1319992_1320208_-	DUF378 domain-containing protein	NA	NA	NA	NA
AYA34354.1\|1321892_1322807_-	rotamase	NA	NA	NA	NA
AYA34355.1\|1324025_1324973_+	peptidase	NA	NA	NA	NA
AYA34356.1\|1324939_1325551_-	Spx/MgsR family RNA polymerase-binding regulatory protein	NA	NA	NA	NA
AYA34357.1\|1325706_1326213_+	cysteine hydrolase	NA	NA	NA	NA
AYA34358.1\|1328298_1329300_+	alpha/beta hydrolase	A0A2P1EM31	Moumouvirus	3.9e-10	32.5
AYA34359.1\|1329543_1329750_-	DUF3955 domain-containing protein	NA	NA	NA	NA
AYA34360.1\|1330171_1331131_-\|transposase	IS30 family transposase	H7BW61	unidentified_phage	2.2e-10	26.8
AYA34361.1\|1331971_1332463_+	flavodoxin family protein	NA	NA	NA	NA
AYA34362.1\|1332705_1332906_+	cold-shock protein	Q9AZD3	Lactococcus_phage	3.9e-23	77.3
AYA34363.1\|1333472_1334018_+	hypothetical protein	NA	NA	NA	NA
AYA34364.1\|1334240_1334606_-	hypothetical protein	NA	NA	NA	NA
AYA34365.1\|1334683_1334929_-	XRE family transcriptional regulator	NA	NA	NA	NA
AYA34366.1\|1334998_1335253_-	hypothetical protein	NA	NA	NA	NA
AYA34367.1\|1336247_1336751_-	cysteine hydrolase	NA	NA	NA	NA
AYA34368.1\|1336790_1337600_-	HAD family phosphatase	NA	NA	NA	NA
AYA34369.1\|1337933_1338791_+	glycosyltransferase family 8 protein	A0ZYL4	Archaeal_BJ1_virus	1.3e-19	27.1
AYA34370.1\|1338783_1339686_+	glycosyltransferase family 8 protein	NA	NA	NA	NA
AYA34371.1\|1339718_1340069_+	iron-sulfur cluster biosynthesis family protein	NA	NA	NA	NA
AYA34372.1\|1340102_1341041_+	magnesium transporter CorA family protein	NA	NA	NA	NA
AYA34373.1\|1341120_1342014_+	SDR family oxidoreductase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	2.0e-58	45.7
AYA34374.1\|1342051_1342615_+	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
AYA34375.1\|1342626_1342815_+	DUF2273 domain-containing protein	NA	NA	NA	NA
AYA34376.1\|1342827_1343727_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
AYA34377.1\|1343758_1344001_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
AYA34378.1\|1344288_1344660_-	hypothetical protein	NA	NA	NA	NA
AYA34379.1\|1345269_1349733_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
AYA34380.1\|1349901_1351365_+	hypothetical protein	NA	NA	NA	NA
AYA34381.1\|1351486_1351720_-	transcriptional regulator	NA	NA	NA	NA
AYA34382.1\|1351728_1352202_-	DUF2975 domain-containing protein	NA	NA	NA	NA
AYA34383.1\|1352526_1353699_+\|transposase	IS256 family transposase IS1542	A0A0N9STL0	Staphylococcus_phage	1.3e-121	88.8
AYA34384.1\|1353822_1354782_-\|transposase	IS30 family transposase	H7BW61	unidentified_phage	2.2e-10	26.8
AYA34385.1\|1357222_1358473_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	2.7e-109	63.0
AYA34386.1\|1358879_1359461_+	copper ABC transporter permease	NA	NA	NA	NA
AYA34387.1\|1359457_1359613_+	cyclic lactone autoinducer peptide	NA	NA	NA	NA
AYA34388.1\|1359564_1359765_-	hypothetical protein	NA	NA	NA	NA
AYA34389.1\|1360280_1360847_+	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
AYA34390.1\|1360859_1361048_+	DUF2273 domain-containing protein	NA	NA	NA	NA
AYA34391.1\|1361060_1361618_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
AYA34392.1\|1361649_1361892_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
AYA34393.1\|1362106_1363066_+\|transposase	IS30 family transposase	H7BW61	unidentified_phage	7.5e-11	26.8

DBSCAN-SWA_4

1636002 : 1645041

Synechococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYA34634.1\|1636002_1636581_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.3e-26	36.9
AYA35525.1\|1636577_1637621_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	2.9e-61	43.9
AYA34635.1\|1637652_1639092_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.3e-53	33.1
AYA34636.1\|1639076_1641299_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-151	41.4
AYA34637.1\|1641299_1641971_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AYA34638.1\|1641972_1642227_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AYA34639.1\|1642226_1642955_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	1.1e-41	40.9
AYA34640.1\|1643210_1643588_+	hypothetical protein	NA	NA	NA	NA
AYA34641.1\|1643745_1645041_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.0e-18	33.1

DBSCAN-SWA_5

2015084 : 2023799

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYA34980.1\|2015084_2017274_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	6.8e-286	66.7
AYA35534.1\|2017477_2017657_-	hypothetical protein	NA	NA	NA	NA
AYA34981.1\|2017831_2018434_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A288TZV3	Enterococcus_phage	4.9e-53	58.0
AYA34982.1\|2018487_2019609_-	DNA polymerase IV	NA	NA	NA	NA
AYA34983.1\|2019717_2020590_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	2.1e-89	60.1
AYA34984.1\|2020658_2021006_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	5.1e-18	41.1
AYA34985.1\|2020998_2021823_-	signal peptidase	NA	NA	NA	NA
AYA34986.1\|2021858_2022797_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.1e-34	33.8
AYA34987.1\|2022810_2023140_-	hypothetical protein	NA	NA	NA	NA
AYA34988.1\|2023154_2023799_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.4e-58	52.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP032307

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP032308

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection