CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP032464	Lactobacillus plantarum strain ATG-K6 chromosome, complete genome	1 crisprs	RT,csa3,cas3,DEDDh,DinG,csn2,cas2,cas1,cas9,WYL	0	3	6	0
CP032465	Lactobacillus plantarum strain ATG-K6 plasmid pK6, complete sequence	0 crisprs	csa3	0	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP032464_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP032464_3

2812570-2813265

TypeII

Consensus_repeat	Method
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	CRT
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	PILER-CR
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	CRISPRCasFinder

10 spacers

csa3,csn2,cas2,cas1,cas9

The CRISPR arrays of CP032464_3

>merge|CP032464|3|2812570-2813265|CRT,PILER-CR,CRISPRCasFinder
CGTGAAACTGTTTTTGATGTGGCCGCTATTCAAGACAAACGTTCTATGCTTCGTTTCCTCAGCATCGTTCTAAACCTGTTTGATATGACTACTATTCAAGACCGTGTCTTGTTCCTTGTTGTACTCCATACCGTTCTAAACCTGTTTGATATGACTACTATTCAAGACGGGAGTGATAGACGTTGAGCGACACTGTACGTTCTAAACCTGTTTGATATGACTACTATTCAAGACGGACGCTCGCAAACAACGCTGCACTCAATAGTTCTAAACCTGTTTGATATGACTACTATTCAAGACAACTTGTTGGTGCCCCAGAAGAGTCATCAAGTTCTAAACCTGTTTGATATGACTACTATTCAAGACTAATCGGCGTGGTGAAGATTTCGCCGACGTGTTCTAAACCTGTTTGATATGACTACTATTCAAGACATCGACACGGTAAGACCGTTAACGGTGTTTGTTCTAAACCTGTTTGATATGACTACTATTCAAGACAGCCAATGAATGACTACGCTAAAGACGTTTGTTCTAAACCTGTTTGATATGACTACTATTCAAGACATCAATAACTGGGCGTCAGCATTAATTCGAGTTCTAAACCTGTTTGATATGACTACTATTCAAGACAACTGAGGCAACCCCAGCAGGAGTCTGTTGGTTCTAAACCTGTTTGATATGACTACTATTCAAGAC

>CP032464|3|1|2812570-2813265|CRT
CGTGAAACTGTTTTTGATGTGGCCGCTATTCAAGAC	AAACGTTCTATGCTTCGTTTCCTCAGCATC
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	CGTGTCTTGTTCCTTGTTGTACTCCATACC
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	GGGAGTGATAGACGTTGAGCGACACTGTAC
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	GGACGCTCGCAAACAACGCTGCACTCAATA
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	AACTTGTTGGTGCCCCAGAAGAGTCATCAA
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	TAATCGGCGTGGTGAAGATTTCGCCGACGT
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	ATCGACACGGTAAGACCGTTAACGGTGTTT
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	AGCCAATGAATGACTACGCTAAAGACGTTT
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	ATCAATAACTGGGCGTCAGCATTAATTCGA
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	AACTGAGGCAACCCCAGCAGGAGTCTGTTG
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC

>CP032464|3|1|2812636-2813265|PILER-CR
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	CGTGTCTTGTTCCTTGTTGTACTCCATACC
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	GGGAGTGATAGACGTTGAGCGACACTGTAC
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	GGACGCTCGCAAACAACGCTGCACTCAATA
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	AACTTGTTGGTGCCCCAGAAGAGTCATCAA
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	TAATCGGCGTGGTGAAGATTTCGCCGACGT
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	ATCGACACGGTAAGACCGTTAACGGTGTTT
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	AGCCAATGAATGACTACGCTAAAGACGTTT
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	ATCAATAACTGGGCGTCAGCATTAATTCGA
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	AACTGAGGCAACCCCAGCAGGAGTCTGTTG
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC

>CP032464|3|3|2812636-2813265|CRISPRCasFinder
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	CGTGTCTTGTTCCTTGTTGTACTCCATACC
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	GGGAGTGATAGACGTTGAGCGACACTGTAC
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	GGACGCTCGCAAACAACGCTGCACTCAATA
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	AACTTGTTGGTGCCCCAGAAGAGTCATCAA
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	TAATCGGCGTGGTGAAGATTTCGCCGACGT
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	ATCGACACGGTAAGACCGTTAACGGTGTTT
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	AGCCAATGAATGACTACGCTAAAGACGTTT
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	ATCAATAACTGGGCGTCAGCATTAATTCGA
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC	AACTGAGGCAACCCCAGCAGGAGTCTGTTG
GTTCTAAACCTGTTTGATATGACTACTATTCAAGAC

Protein	Signature genes	Signature genes Name	Protein_function
CP032464.1\|AYC75911.1\|2820518_2821226_-\|hypothetical-protein	unknown	unknown	unknown
CP032464.1\|AYC75899.1\|2806121_2806577_+\|DUF3021-domain-containing-protein	unknown	unknown	gnl\|CDD\|378668
CP032464.1\|AYC75901.1\|2807232_2807706_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
CP032464.1\|AYC75910.1\|2819711_2820494_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP032464.1\|AYC75912.1\|2821343_2822708_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182694
CP032464.1\|AYC75915.1\|2825362_2826103_-\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|224982
CP032464.1\|AYC75908.1\|2814246_2815152_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
CP032464.1\|AYC75905.1\|2809766_2812505_+\|cation-transporting-P-type-ATPase	unknown	unknown	gnl\|CDD\|319775
CP032464.1\|AYC75902.1\|2807818_2808421_+\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|377026
CP032464.1\|AYC75896.1\|2803829_2804195_-\|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
CP032464.1\|AYC75903.1\|2808486_2808681_+\|PspC-domain-containing-protein	unknown	unknown	gnl\|CDD\|377200
CP032464.1\|AYC75909.1\|2815346_2819423_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
CP032464.1\|AYC75897.1\|2804219_2805452_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340949
CP032464.1\|AYC75914.1\|2823526_2825119_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|214906
CP032464.1\|AYC75913.1\|2822940_2823411_+\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|240033
CP032464.1\|AYC75907.1\|2813963_2814269_-\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
CP032464.1\|AYC75906.1\|2813289_2813967_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
CP032464.1\|AYC75898.1\|2805618_2806125_+\|LytTR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197918
CP032464.1\|AYC75900.1\|2806664_2807087_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|107228
CP032464.1\|AYC75904.1\|2808723_2809482_-\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|350158

Protein	Function_ID	Function_description	E-value
CP032464.1\|AYC75915.1\|2825362_2826103_-\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	gnl\|CDD\|224982	COG2071, COG2071, Predicted glutamine amidotransferases [General function prediction only].	4.48973e-88
CP032464.1\|AYC75899.1\|2806121_2806577_+\|DUF3021-domain-containing-protein	gnl\|CDD\|378668	pfam11457, DUF3021, Protein of unknown function (DUF3021). This is a bacterial family of uncharacterized proteins.	1.50722e-25
CP032464.1\|AYC75901.1\|2807232_2807706_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	0.000255443
CP032464.1\|AYC75910.1\|2819711_2820494_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.18043e-25
CP032464.1\|AYC75912.1\|2821343_2822708_-\|amino-acid-permease	gnl\|CDD\|182694	PRK10746, PRK10746, putative transport protein YifK; Provisional.	0
CP032464.1\|AYC75908.1\|2814246_2815152_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	6.41428e-89
CP032464.1\|AYC75905.1\|2809766_2812505_+\|cation-transporting-P-type-ATPase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
CP032464.1\|AYC75902.1\|2807818_2808421_+\|NADPH-dependent-oxidoreductase	gnl\|CDD\|377026	pfam03358, FMN_red, NADPH-dependent FMN reductase.	3.68426e-30
CP032464.1\|AYC75896.1\|2803829_2804195_-\|ArsR-family-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	7.3086e-14
CP032464.1\|AYC75903.1\|2808486_2808681_+\|PspC-domain-containing-protein	gnl\|CDD\|377200	pfam04024, PspC, PspC domain. This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator. The presumed domain is 60 amino acid residues in length.	2.12668e-17
CP032464.1\|AYC75909.1\|2815346_2819423_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	2.66373e-128
CP032464.1\|AYC75897.1\|2804219_2805452_-\|MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.1962e-140
CP032464.1\|AYC75914.1\|2823526_2825119_-\|DNA-binding-protein	gnl\|CDD\|214906	smart00910, HIRAN, The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. HIRAN is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, such as a nuclease of the restriction endonuclease fold and TDP1-like DNA phosphoesterases, in the eukaryotes. It has been predicted that this protein functions as a DNA-binding domain that probably recognises features associated with damaged DNA or stalled replication forks.	4.86772e-17
CP032464.1\|AYC75913.1\|2822940_2823411_+\|NUDIX-domain-containing-protein	gnl\|CDD\|240033	cd04677, Nudix_Hydrolase_18, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	8.22877e-58
CP032464.1\|AYC75907.1\|2813963_2814269_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.01798e-25
CP032464.1\|AYC75906.1\|2813289_2813967_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.34637e-80
CP032464.1\|AYC75898.1\|2805618_2806125_+\|LytTR-family-transcriptional-regulator	gnl\|CDD\|197918	smart00850, LytTR, LytTr DNA-binding domain. This domain is found in a variety of bacterial transcriptional regulators. The domain binds to a specific DNA sequence pattern.	2.71307e-18
CP032464.1\|AYC75900.1\|2806664_2807087_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|107228	cd06471, ACD_LpsHSP_like, Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers consisting of multiple subunits. Transcription of the genes encoding Lp HSP 18.5, 18.55 and 19.3 is regulated by a variety of stresses including heat, cold and ethanol. Early growing L. plantarum cells contain elevated levels of these mRNAs which rapidly fall of as the cells enter stationary phase. Also belonging to this group is Bifidobacterium breve (Bb) HSP20 and Oenococcus oenis (syn. Leuconostoc oenos) (Oo) HSP18. Transcription of the gene encoding BbHSP20 is strongly induced following heat or osmotic shock, and that of the gene encoding OoHSP18 following heat, ethanol or acid shock. OoHSP18 is peripherally associated with the cytoplasmic membrane.	2.67238e-43
CP032464.1\|AYC75904.1\|2808723_2809482_-\|purine-nucleoside-phosphorylase	gnl\|CDD\|350158	cd09007, NP-I_spr0068, uncharacterized subfamily of the nucleoside phosphorylase-I family. This subfamily is composed of uncharacterized members including Streptococcus pneumoniae hypothetical protein spr0068. The nucleoside phosphorylase-I (NP-I) family members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases such as purine nucleoside phosphorylase (PNP, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases such as AMP nucleosidase (AMN, EC 3.2.2.4) and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). Members of the NP-I family display different physiologically relevant quaternary structures: hexameric (trimer-of-dimers arrangement of Shewanella oneidensis MR-1 UP); homotrimeric (human PNP and Escherichia coli PNPII or XapA); hexameric (with some evidence for co-existence of a trimeric form) such as E. coli PNPI (DeoD); or homodimeric such as human and Trypanosoma brucei UP. The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	7.05874e-91

>CP032464.1|AYC75905.1|2809766_2812505_+|cation-transporting-P-type-ATPase
MIKDDNQSLTSNEEQNDTQNPPDADNLWQLDESALAAKYTTDPENGLSTAEAAERLQHNGRNELETKRTSRFVQFIKQFNNSIIYILAAAAVLTFFMHHYSDSIVIGLVIIANAIIGYVQERQAGNALERIREMLISKNFVIRDGKKLEIDARELVVGDLVNLEAGDAVPADMRLISADNFNVQESVLTGETNPVEKQEEPMTETTLALADRKNMVYASTAVTSGSAVGIVTATAEDTEIGHIQQSVSDVKQTTTPLMRNLNSLGVGLSIAIVVAAVLLFLLGMVMDTYSLPTLLIAVITMVVGSMPEGLPASTSVVLAMGTRQMTKKNVIVKSLPAVETLGAVDIVNTDKTGTLTKNEMTVTKVVTPEHTFDVTGVGYDDNGGVNFDGHLKLNGNKVDWHQDNAMEWLVKIAGQTTDAELHFENNRWELTGEPTDGALTTLYRKMTGHDPEVEEVDSLPFDSAFRFSARLADLDGQRLLMVKGSPATVLRLTDQANQTAYWDDAMDDLTADGLRVVALAYQEVDDDVTTIDAQAIGGLHLAGLVGIIDPPREEAATAIAELRQAGVQVKMITGDHPDTAMAIANKLNLAANVKAITGPEIDAMDDQQLQAHIDDYNVFARATPNNKLRIVRAQQANNHVVSMTGDGVNDAPALKQADIGVAMGIKGTEVAKESADMVLADDDFADIVAAVREGRHVFDNIRKTIRFLLPTSFAEGLVVIISILMGHELPLYPTQLLWINMVSALTIQFAFIFEPPEAGIMARGPRNVKSGLLSKLDYFEIGYVSFLISGLGIFAYNYLTALGLPNVVGSTMSLNIIIFGKIFYLFNLRNDHPVISKYFFQNKMAFYIIGILILLQLGIIYLPFMQSVFHTTSINFWYGWGIPIICGIVVLIVTEVGKFIRFRWMGKDGVID
>CP032464.1|AYC75904.1|2808723_2809482_-|purine-nucleoside-phosphorylase
MTDKLTLLQYDPNPTAMVGPDVDGRFTVPAKLLYIFSGDDYFQQFVTRYHGHRLGQFNTITKVSWVYQIGYRGQKLAVAQAPLGSPAATMYLEMLIDFGARTVIAVGSCGALTALPEEQLLIPTVALRDEGTSFHYLAAADWVPLDPKVIQVLGTTLTKACLPWQMVKTWTTDAFFRETVSKVKAARQQGCQVVEMECSALAACSAFRQVSFGQLLYTADTLAQLEHYDPRHWGAGGVLAAIELAVESLAAY
>CP032464.1|AYC75903.1|2808486_2808681_+|PspC-domain-containing-protein
MKIDIHRSATDRVIAGVIGGIAEHFNWNTNVTRLLFVVLAITPMFPGIIAYLILWLLMKDPIKD
>CP032464.1|AYC75902.1|2807818_2808421_+|NADPH-dependent-oxidoreductase
MFKIAIILGSTRSQANGRALLNHLKLIIDQLPTHSPIHYQFLDLANYQLPFFDEPESPMANPHRELPANQQQWLTDMASADGYIILTPEYNHAMPAGLKNAFDFLAFEGARKPAKIISYSDNMRGGQFGAAALVPVLQRLGIVVLPKPTPIGNVPQTLQSNGHFIDNAPLSKRYDHTLHQALTEITYYTTVLTTTPFPTD
>CP032464.1|AYC75901.1|2807232_2807706_-|MarR-family-transcriptional-regulator
MTTPLVSQLMTELNQFLTQDSVDDQEKRWAMQQTTDPQLQAALKQLSTTDIKIMAYLGRRGASRAKSLPAPTELSQATISRGLTKLSRLKLATKYRDLTNNKEILVRLTTLGEAVADLHTQLDATIAAKAQAIADDYSDAELRRFVSLMRRIREIKI
>CP032464.1|AYC75900.1|2806664_2807087_-|Hsp20/alpha-crystallin-family-protein
MANTLMNRNDFGMLDPFERMARSFWAPLENMDQVLKTDINETDDQYQVKVDVPGIDKQDVKLDYRDNVLSIKVQKDSFVDHEDQDQNIVMNERHTGTLQRQYMLPNVAANKITASQADGVLTITLPKTQPSANDGQIEIQ
>CP032464.1|AYC75899.1|2806121_2806577_+|DUF3021-domain-containing-protein
MKRLWHTLLIGAIGGIVIGYLMALGFSTFFNTTYLFPSNPTFVSHWSSPLAATQLSTLLWILIGEVWAFSSWLFEIETWSITKQTIAHCLCSFLGMTPLAILCGWFPLNVRWFGFYTLVYTGAYIGLWLIEMALARIKVIQLNQQLTNQRS
>CP032464.1|AYC75898.1|2805618_2806125_+|LytTR-family-transcriptional-regulator
MSSRIFTTISLSKSLFKGESTRHVQLTISETIHQVFVTIHGPQLTPAIKELQRNIEALTNQQFINVFQDRSLIKLPLQSVSRFYTANKRLYCETTTGAYLVHSHLHTLMDQLPPHQFLRISSSEIVRIACVKNFTLTKWGSFQVNLTTGTTTYASRRYTQQIRKAAQL
>CP032464.1|AYC75897.1|2804219_2805452_-|MFS-transporter
MDDAERERGPWHRNLIVLWFCTFVAGMAFSEIMPFLSLFVSQLGDFTKAQITFYSGLAFAADYAISAISAPLWGIIADKKGRKIMLLRASLGMAVAMGLMGFVTNVWQLVALRALQGVFAGFISNAQALVASQTPRKYSGRALSTLITGAVSGQLFGPVIGGLLAQLFSIRNTFFITAGLLMVAFLLSLFFVQEHFKPVAHHREPGDSRNPLAAFQNPRLIIVMLCSTAIVQFGNASIAPIISLYVRELMHYRGPITVVAGIIAALPGISNIFSAPRLGRYGDQHGSGKVLLFGYIFAVIMYFPQGIVTSVVALGILRFAIGISDGALYPEIQTVLTKNTPVHLTSTIFSYNQSFQAIGNMFGALLGGLVAGWFNYNAVFIMTALLLLINLGLILWLVPDIWKNGKRAVS
>CP032464.1|AYC75896.1|2803829_2804195_-|ArsR-family-transcriptional-regulator
MASCLFCYLSLNMMLIQCIVSFMNIEISKQDQADQQRVAIFKALADANRLRIIRVLYQAQREMTCSEVGAQLNISKSTVSYHFKTLRLVGLTNTRRKAQTKYLSLQLATFDRFLPGFLATL
>CP032464.1|AYC75906.1|2813289_2813967_-|type-II-A-CRISPR-associated-protein-Csn2
MNITYYPFPPFKIDAGKVNVLDLGNSNMYAEVCQGFRDRIDSVRISNDDLELQTISSQCNWYGDLMLSVDLNRLFLKKVQTQIIKLMADDRQVAVLDENRKVVSQVMEASFLLDLPLDVDESPSLEQILKFTGVHFPTELMNDPRAILEALVQTHVELGLKQKLVLTNVSHYLNQKQWASFEQLVHDLGATVIVIEYSEINRMEKFKNSCYYYVDEDLVDWRDMN
>CP032464.1|AYC75907.1|2813963_2814269_-|CRISPR-associated-endonuclease-Cas2
MRLIVMFDVPMDTSEERRAYRHFHKALVREGFLMMQYSTYVRVCVNKKAAEFVEKRIAPLAPKGGKVQTMTVTEKQYQAMHYIQGTPSNDILNSAERTIVI
>CP032464.1|AYC75908.1|2814246_2815152_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRNVIITQHAKVSYSMNRILVQTSSDKYAVPISDIQLLLVGTTQAVITSAALCALAEAHVKVIFTDHQGEPISETNDYYPTRRTADLVRQQVTWPEARIATLWTKNVGSKILNQIQVIDFVGGDTQTLVDELDKLELNDVTNREAVVANKYFSLLFGAQFYRRDFSPINAALNYGYAVLLSMVNREIVLNGYLTCIGIHHENNENEFNLGSDLMEPFRPIVDQWVSQQRFKDFTPDIKIGLVSLLDLEIGFNGHQTIVSHAITEYVAACLHYLSGETEELKIEVKLPNEVSSDAINSHV
>CP032464.1|AYC75909.1|2815346_2819423_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKEPYGVGLDIGTNSVGWTVVDASGHVRKIKGQTGIGVRLFKEGAAAADRRGFRTTRRRLKRVKWRLRLLREFFDQPISKVDINFFARRKYSDISPRDPNYNGLEKTLFNDRSDQDFYHDYPTIYHLREALMTQHRKFDVREIYLAIHHIVKYRGNFLRNDAATAYRSGTLDLQQHFETLNHLFSQADLELNLNLTTDVALLDSIKQTLVRTDISRSDRQKLIMPLLAVLTGATTAEKKRQKAVVTEFAKALVGNKTKIDVLTLTDIDATEAKDWAFSLEENQDKLPGIEDRFSEVGQQIIDEVIRLYASVNLAQLIPEGKRFSQSMVEKYKRHGEDLKLLKAYIRSQSDAKRGRAIRATYDQYIDGVKSKQVTQEAFQKALGKFVDADVDLNSWAAQIKQAIDSEQFMPKLRIKQNGAIPYQVQQNELDQIISNQKEYYPWLGEENPVIKRRGKFPYKLDELVGFRVPYYVGPLITKEMQAATANAGFAWMVRKADGPITPWNFDDKVDRVASATAFIQRMQTTDTYLIGEEVLPARSLIYQRFMVLNELNNIRVDDGQLTPRQKQRLYNQVFKKHKRVTAKNIQDNLVAAGEFPTAPRITGLADPKVFNSSLSTYHDLKQVLPEAMSDVRKQADIEKIILWSTIFEDSTIFKQKLTEISWLTAAQLKQLGQLRYRGWGQLSRKLLTGLKDDNNRSIMDGLWETNANFMQLRSQPAIENQIKSANQANLTTADLQDTINELYTSPQNKKAIREVMVVLADIKDAMHGQTPNWIFVEAARGGGVAGRRTQSRSKQIVAAYQGTAQAIVSDQVQRELKEKIKNKANFNTRLVLYFLQNGRDLYTGDAINIDRLSEYDIDHILPQSLVKDDSLDNRVLTNARINREKNDTFASEKFGKKMGAKWKEMHRMGLMTKRKLDHLLMRPDEISKYATGFINRQLVETRQVIKLVEELINAEYPSTAIVSVKANLTHQFRQTFDFPKIREVNDYHHAFDAALTAFIGTYLLKRYPKLERFFVYGKFAKQPVNLTRFNVIRKLAKTDTPITDIDTGEVLWDKLTDIKYFETLYDYKRLLVTREVSENYGAMFDQTLLKASDNGKRLIRKKQSFDTAIYGGYTGKTLAYMAIVKVSTKKDVQYQVVGVPTTMVTQIEQLEQQGMTNKQAVTKVIEPLIAANNKKMLTYEVLLPKVRFEQVVRDRIKGQTHRFALGTDTYYHNIQELYLPLTLQRAFLGKQNESEVQLNQNLLTVFDATLAQVNRYFPLYEMNKFKKILNSARDQIELLEAKNQFVKNKLVLGKQGILTNMFIGLHANASYGDLKVLGVKTDFGKLQVPGGIKLTGDAEIIYQSPTGLFERKISLKDL
>CP032464.1|AYC75910.1|2819711_2820494_-|alpha/beta-hydrolase
MRFITSDHVQLDYTDEGQGQPIVILTGFGGAKDIWRAQIPVLIQAGYRVINLDGRCQGLSEHTAKGLRMSRRAVDAHELIEKLQLKQPILLGNSMGAATWFAYVSLYGDTGIKALIDVDQTPRMINTPHWQYGFKQVQWQDIPDYFRMPLGHSTFKHIDDATYARVKAVEAQAPFDAKLMFPLLVNHAVQDWRDVIRQLTVPFLIIAGAKSPFFNPDFAAVTAQMALRGQSVVIPEAGHIVMAEQSVAFNKALLEFLATC
>CP032464.1|AYC75911.1|2820518_2821226_-|hypothetical-protein
MVKQGHYAKVSKQKRLRQLKQRRQAQEKRAIMPEMVSEFLQVRYHLTQAAKQRPAMRQMMQRFMAQWLAAGQAELSDNGQTTWSVVALTKQTLQTFNRQLPWQGYALVDQEMARWTAFLNKEVPAVPLSERITLTEALSPATWQACLSEQLAINALLALTGDSRQLGQITTEQVRQLQTSIQTATGIDWEKVAQLLDLTVIAQNTLSKAGLDDKTRQWLEKLKKLTPQDFNDHVE
>CP032464.1|AYC75912.1|2821343_2822708_-|amino-acid-permease
MQRKLSTGQMQMIALGGTIGVGLFMGSSSTIKWTGPSVLIAYIVSGAFLYLIMRALGEMLYVDPNTGSFAKFASEYIHPVFGYLTAWSNIFQFVVVGMSEMIALGGYCRYWWPNLPDWIPGLIAIVFLCAANLISVKMFGTLETWFSLIKVVTIILMIIAGLGLIIFGIGNGGHPIGISNLWTHGGFFTGGVKGFVFALAIVLASYQGIELIGVTAGEAENPQSTIVKAIRSTVARILIFYVGAIFVIVSIYPWDKLSQIGSPFVQTFAKIGITAAASIINFVVITASLSGTNSGIYSASRMTYTLAESHQLPRKMTLLNRHGVPFYSVIAIATGILIGVVLNVVLPMFFKDASEIFVMVYSSSVLPGMVPWFVILVSQIAFRKQNAAKMANHPFKMPLSPYSNYLTLAFLALTLVFMFINPETRYSILVGVVFLVIMTLIYFRKYAGNKEETL
>CP032464.1|AYC75913.1|2822940_2823411_+|NUDIX-domain-containing-protein
MANYIKEIRALVGHKPIILNTAAGILVNDQQQVLLNLRTDTHNWSLPGGYLEYGETYATACVREYKEDSGIDVEVVDRIGIFDKGETAYPNGDVAQTISALFLVKPIGGHVLTQATDETLKLDYFDFDNLPPLLNQQNADMIHAAQEYLQTHSATK
>CP032464.1|AYC75914.1|2823526_2825119_-|DNA-binding-protein
MERIEAGMSVMTLKKQTYRVIAVINQGQELLVRAHEPETADIEIIPVTTVVQVTEQNSTGDAAVALDTVTVVGERYVDDIVATLTTLRVGMAVLLQRESGNQYDDNAISVWTLQHAKLGYIARYQNQPYAALMDQGQRLYGIVTVLDQQKQHLELMLWRTTAVPSPIEALQIRQRLAKPRTNLGAVPTHSLQTPLGTIVMMCNGHPIKYQQVPLSPWLTPADELHVTKRYLLTPDWSQVPPDSLITCQVTAKADVVQRWQNEHISAAVLTNASSFYVVVISAQTKTGLNDNLVDDAAQPAVIYRVGQVSAHMQAGFMVSWAPFGDPRVQPALKLALHFSSQPLVPYHPVTPSRTNATFTQQELAALLVSALPNYQGGQRLEPSVTAITVEKLRQTLGDQTYHALANYQRHVQLVAGSTEGVNETLLQALIHAVTYHELTTMHYYQPTVGMVDQVIYPIQLFSTTTKDEDDAQLVGCLALYNYETFEIQQVPLTAIARIAIIADPEHPQTTPETESPDWLRIFLHGWNDDF
>CP032464.1|AYC75915.1|2825362_2826103_-|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein
MVKPIIGIAPGVVTVNSQMFPGRVRDYVNRDYLKSVTDNGGVPLVLPVTTDATTIERYVGMIDGLLLCGGADVAPLTYGEEPQPKLGGVDPERDQYEIALIRATHAVGKPVLGICRGLQILNVCYGGNLYQDMSELPAGQGTLKHMQGQLAAYGMHHVKVVPGTTLAEYLGTTSDAITVNSFHHQAVKQVATGFQVVAQSADQVVEAIEATAGGLQLGVQWHPEMMQQVNSVQARLFAAFMRACVA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP032464_3	3.4\|2812804\|30\|CP032464\|CRT,PILER-CR,CRISPRCasFinder	2812804-2812833	30	NZ_CP025993	Lactobacillus plantarum subsp. plantarum strain LB1-2 plasmid pLB1-2B, complete sequence	51476-51505	0	1.0
CP032464_3	3.6\|2812936\|30\|CP032464\|CRT,PILER-CR,CRISPRCasFinder	2812936-2812965	30	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	284024-284053	4	0.867
CP032464_3	3.6\|2812936\|30\|CP032464\|CRT,PILER-CR,CRISPRCasFinder	2812936-2812965	30	AB981169	Ralstonia phage RSY1 DNA, complete genome	19536-19565	6	0.8
CP032464_3	3.6\|2812936\|30\|CP032464\|CRT,PILER-CR,CRISPRCasFinder	2812936-2812965	30	NC_049432	Ralstonia phage RsoM1USA, complete genome	13669-13698	6	0.8
CP032464_3	3.6\|2812936\|30\|CP032464\|CRT,PILER-CR,CRISPRCasFinder	2812936-2812965	30	NZ_CP039965	Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence	1133280-1133309	6	0.8
CP032464_3	3.4\|2812804\|30\|CP032464\|CRT,PILER-CR,CRISPRCasFinder	2812804-2812833	30	NC_017507	Marinobacter adhaerens HP15 plasmid pHP-187, complete sequence	134270-134299	7	0.767
CP032464_3	3.10\|2813200\|30\|CP032464\|CRT,PILER-CR,CRISPRCasFinder	2813200-2813229	30	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	477512-477541	7	0.767
CP032464_3	3.4\|2812804\|30\|CP032464\|CRT,PILER-CR,CRISPRCasFinder	2812804-2812833	30	KY296500	Xenohaliotis phage pCXc-HC2016, complete genome	22086-22115	8	0.733
CP032464_3	3.4\|2812804\|30\|CP032464\|CRT,PILER-CR,CRISPRCasFinder	2812804-2812833	30	KY296501	Xenohaliotis phage pCXc-HR2015, complete genome	22084-22113	8	0.733

1. spacer 3.4|2812804|30|CP032464|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP025993 (Lactobacillus plantarum subsp. plantarum strain LB1-2 plasmid pLB1-2B, complete sequence) position: , mismatch: 0, identity: 1.0

ggacgctcgcaaacaacgctgcactcaata	CRISPR spacer
ggacgctcgcaaacaacgctgcactcaata	Protospacer
******************************

2. spacer 3.6|2812936|30|CP032464|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 4, identity: 0.867

taatcggcg----tggtgaagatttcgccgacgt	CRISPR spacer
----cggcggtgttggtgaagatttcgccgacgt	Protospacer
    *****    *********************

3. spacer 3.6|2812936|30|CP032464|CRT,PILER-CR,CRISPRCasFinder matches to AB981169 (Ralstonia phage RSY1 DNA, complete genome) position: , mismatch: 6, identity: 0.8

taatcggcgtggtgaagatttcgccgacgt	CRISPR spacer
cgatcggcgtggtgaggatgtcgccgatgg	Protospacer
..*************.*** *******.*

4. spacer 3.6|2812936|30|CP032464|CRT,PILER-CR,CRISPRCasFinder matches to NC_049432 (Ralstonia phage RsoM1USA, complete genome) position: , mismatch: 6, identity: 0.8

taatcggcgtggtgaagatttcgccgacgt	CRISPR spacer
caatcggcgtggtgaggatgtcgcccatgg	Protospacer
.**************.*** ***** *.*

5. spacer 3.6|2812936|30|CP032464|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP039965 (Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

taatcggcgtggtgaagatttcg-ccgacgt	CRISPR spacer
ctatcggcgtggtgaatatttcgactgacc-	Protospacer
. ************** ****** *.***

6. spacer 3.4|2812804|30|CP032464|CRT,PILER-CR,CRISPRCasFinder matches to NC_017507 (Marinobacter adhaerens HP15 plasmid pHP-187, complete sequence) position: , mismatch: 7, identity: 0.767

ggacgctcgcaaacaacgctgcactcaata	CRISPR spacer
agagtctcgcaaacaacgttgcactcaggt	Protospacer
.**  *************.********.

7. spacer 3.10|2813200|30|CP032464|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

aactgaggcaaccccagcaggagtctgttg	CRISPR spacer
ggccggggcaaccccggcaggagtgtgttt	Protospacer
..*.*.*********.******** ****

8. spacer 3.4|2812804|30|CP032464|CRT,PILER-CR,CRISPRCasFinder matches to KY296500 (Xenohaliotis phage pCXc-HC2016, complete genome) position: , mismatch: 8, identity: 0.733

ggacgctcgcaaacaacgctgcactcaata	CRISPR spacer
ctgtgatctcaaacaacgctgcaatcaatg	Protospacer
  ..* ** ************** *****.

9. spacer 3.4|2812804|30|CP032464|CRT,PILER-CR,CRISPRCasFinder matches to KY296501 (Xenohaliotis phage pCXc-HR2015, complete genome) position: , mismatch: 8, identity: 0.733

ggacgctcgcaaacaacgctgcactcaata	CRISPR spacer
ctgtgatctcaaacaacgctgcaatcaatg	Protospacer
  ..* ** ************** *****.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

560856 : 569370

Synechococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYC73863.1\|560856_561342_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.3e-16	41.0
AYC73864.1\|561325_562456_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
AYC73865.1\|562458_563190_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4SM18	Cyanophage	2.1e-37	37.3
AYC73866.1\|563191_563446_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AYC73867.1\|563445_564126_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AYC73868.1\|564118_566338_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.5e-144	39.1
AYC73869.1\|566322_567777_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.3e-50	34.0
AYC73870.1\|567773_568799_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	9.3e-60	41.3
AYC73871.1\|568791_569370_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.3e-21	33.9

DBSCAN-SWA_2

763300 : 813369

Lactobacillus_phage(36.36%)

tail,capsid,portal,terminase,head,integrase

attL 763129:763143|attR 816311:816325

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
763129:763143	attL	NA	NA	NA	NA
AYC74047.1\|763300_764458_-\|integrase	site-specific integrase	Q938N9	Temperate_phage	5.0e-54	34.8
763129:763143	attL	NA	NA	NA	NA
AYC74048.1\|764508_765159_-	XRE family transcriptional regulator	A0A1W6JQE6	Staphylococcus_phage	3.6e-09	46.5
AYC74049.1\|765336_765519_+	DNA-binding protein	NA	NA	NA	NA
AYC74050.1\|765561_765669_+	hypothetical protein	NA	NA	NA	NA
AYC74051.1\|765789_766020_+	hypothetical protein	NA	NA	NA	NA
AYC74052.1\|766033_766834_+	DNA replication protein	NA	NA	NA	NA
AYC74053.1\|768373_768853_+	hypothetical protein	NA	NA	NA	NA
AYC74054.1\|768868_769060_+	hypothetical protein	NA	NA	NA	NA
AYC74055.1\|769046_769385_+\|head,tail	head-tail adaptor protein	A0A2P0ZLF0	Lactobacillus_phage	1.3e-07	34.7
AYC74056.1\|769377_769767_+	HNH endonuclease	A0A1J0MFT4	Staphylococcus_phage	3.0e-19	44.7
AYC74057.1\|770777_771251_+\|terminase	phage terminase small subunit P27 family	NA	NA	NA	NA
769813:769827	attR	NA	NA	NA	NA
AYC74058.1\|771247_772951_+\|terminase	terminase large subunit	A0A2H4JBN3	uncultured_Caudovirales_phage	2.2e-122	41.1
769813:769827	attR	NA	NA	NA	NA
AYC74059.1\|772904_773105_+	hypothetical protein	NA	NA	NA	NA
AYC74060.1\|773105_774206_+\|portal	phage portal protein	A0A2H4J9Q5	uncultured_Caudovirales_phage	1.4e-48	34.0
AYC74061.1\|774202_775747_+\|capsid	phage major capsid protein	B8R651	Lactobacillus_phage	8.2e-44	25.6
AYC74062.1\|775835_776105_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
AYC74063.1\|776255_776633_+	hypothetical protein	NA	NA	NA	NA
AYC74064.1\|776711_777185_+	DUF4065 domain-containing protein	NA	NA	NA	NA
AYC74065.1\|777190_777772_+	hypothetical protein	NA	NA	NA	NA
AYC74066.1\|778185_778392_+	hypothetical protein	NA	NA	NA	NA
AYC74067.1\|778742_779864_-\|integrase	site-specific integrase	D6PSS4	Lactobacillus_phage	2.0e-47	33.0
AYC74068.1\|780129_781749_-	hypothetical protein	A0A1S5SA14	Streptococcus_phage	3.1e-94	47.9
AYC74069.1\|782347_782536_-	hypothetical protein	E9LUS5	Lactobacillus_phage	2.1e-26	100.0
AYC76257.1\|782693_783146_-	hypothetical protein	A0A173G9H4	Propionibacterium_phage	5.2e-07	60.0
AYC74070.1\|783601_784024_-	ImmA/IrrE family metallo-endopeptidase	A0A0S2SXM3	Bacillus_phage	7.8e-13	35.1
AYC74071.1\|784038_784557_-	XRE family transcriptional regulator	S6C481	Thermus_phage	1.6e-15	34.1
AYC74072.1\|784698_784953_+	XRE family transcriptional regulator	A0A2H4JFN1	uncultured_Caudovirales_phage	1.5e-06	41.3
AYC74073.1\|785109_785391_-	hypothetical protein	NA	NA	NA	NA
AYC74074.1\|785449_785632_+	hypothetical protein	NA	NA	NA	NA
AYC74075.1\|785628_786027_-	DUF2513 domain-containing protein	A0A1P8L6H1	Staphylococcus_phage	5.1e-14	38.4
AYC74076.1\|786026_786257_-	XRE family transcriptional regulator	A0A0K2CNE2	Brevibacillus_phage	8.5e-06	36.8
AYC74077.1\|786398_786605_+	XRE family transcriptional regulator	NA	NA	NA	NA
AYC74078.1\|786604_786901_+	hypothetical protein	NA	NA	NA	NA
AYC74079.1\|787107_787413_+	DUF771 domain-containing protein	NA	NA	NA	NA
AYC74080.1\|787480_787993_+	transcriptional regulator	D6PST4	Lactobacillus_phage	1.8e-27	43.5
AYC74081.1\|788242_788530_-	hypothetical protein	A0A2H4JEH2	uncultured_Caudovirales_phage	1.3e-22	48.9
AYC74082.1\|788597_788726_+	hypothetical protein	NA	NA	NA	NA
AYC74083.1\|788858_789245_+	hypothetical protein	NA	NA	NA	NA
AYC74084.1\|789241_790141_+	recombinase RecT	E9LUM3	Lactobacillus_phage	1.0e-62	47.7
AYC74085.1\|790052_790925_+	hypothetical protein	A0A0P0IZH9	Lactobacillus_phage	1.8e-72	47.6
AYC74086.1\|791005_791794_+	DNA replication protein DnaD	NA	NA	NA	NA
AYC74087.1\|791774_792617_+	ATP-binding protein	O03914	Lactobacillus_phage	2.9e-152	96.1
AYC76258.1\|792773_793496_+	oxidoreductase	Q8SDM9	Staphylococcus_phage	4.2e-51	45.6
AYC74088.1\|793500_794019_+	hypothetical protein	O03915	Lactobacillus_phage	2.9e-54	68.4
AYC74089.1\|794015_794396_+	hypothetical protein	NA	NA	NA	NA
AYC74090.1\|794607_795069_+	transcriptional regulator	D6PSV8	Lactobacillus_phage	3.1e-39	56.3
AYC74091.1\|795478_796498_+	hypothetical protein	NA	NA	NA	NA
AYC74092.1\|796515_797019_+	hypothetical protein	NA	NA	NA	NA
AYC74093.1\|797097_797277_+	hypothetical protein	NA	NA	NA	NA
AYC74094.1\|797245_797518_+	hypothetical protein	A0A2D2W301	Escherichia_phage	4.0e-18	50.6
AYC74095.1\|797741_798062_+	hypothetical protein	A0A1J1J9Q7	Escherichia_phage	1.8e-17	45.6
AYC74096.1\|798119_798635_+\|terminase	terminase small subunit	O03926	Lactobacillus_phage	2.8e-65	88.8
AYC74097.1\|798627_799941_+\|terminase	PBSX family phage terminase large subunit	D2IYW1	Enterococcus_phage	8.6e-127	54.3
AYC74098.1\|799955_801692_+\|portal	phage portal protein	D2IZF6	Enterococcus_phage	7.0e-76	34.4
AYC74099.1\|801691_802603_+\|head	phage head morphogenesis protein	NA	NA	NA	NA
AYC74100.1\|802713_803373_+	DUF4355 domain-containing protein	NA	NA	NA	NA
AYC74101.1\|803386_803758_+	hypothetical protein	A0A0K2CNR0	Brevibacillus_phage	1.5e-07	33.6
AYC74102.1\|803773_804883_+\|capsid	minor capsid protein E	A0A2H4J022	uncultured_Caudovirales_phage	1.8e-61	40.1
AYC74103.1\|804900_805269_+	hypothetical protein	NA	NA	NA	NA
AYC74104.1\|805265_805598_+	hypothetical protein	NA	NA	NA	NA
AYC74105.1\|805598_806090_+	hypothetical protein	NA	NA	NA	NA
AYC74106.1\|806092_806488_+	hypothetical protein	NA	NA	NA	NA
AYC74107.1\|806536_807190_+	hypothetical protein	NA	NA	NA	NA
AYC74108.1\|807218_807737_+	hypothetical protein	NA	NA	NA	NA
AYC74109.1\|807811_808069_+	hypothetical protein	NA	NA	NA	NA
AYC76259.1\|808293_812082_+	tape measure protein	A0A0A7DMV4	Lactobacillus_phage	3.3e-38	57.2
AYC74110.1\|812106_812385_-	hypothetical protein	NA	NA	NA	NA
AYC74111.1\|812457_813369_+\|tail	phage tail family protein	Q9T1A6	Listeria_phage	1.6e-18	30.3
816311:816325	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1117680 : 1202905

Lactobacillus_phage(78.72%)

holin,tail,capsid,portal,terminase,protease,head,integrase,tRNA

attL 1110730:1110747|attR 1177306:1177323

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1110730:1110747	attL	NA	NA	NA	NA
AYC74390.1\|1117680_1118844_-\|integrase	site-specific integrase	B4XYR4	Lactobacillus_phage	1.2e-55	36.5
AYC74391.1\|1119060_1119699_+	hypothetical protein	NA	NA	NA	NA
AYC74392.1\|1119891_1120254_-	hypothetical protein	E9LUS2	Lactobacillus_phage	1.7e-56	91.7
AYC74393.1\|1120410_1120599_-	hypothetical protein	E9LUS5	Lactobacillus_phage	2.1e-26	100.0
AYC74394.1\|1120883_1121759_-	hypothetical protein	NA	NA	NA	NA
AYC74395.1\|1121888_1122572_-	LexA family transcriptional regulator	D7RWL5	Brochothrix_phage	6.2e-52	44.6
AYC74396.1\|1122731_1122980_+	transcriptional regulator	A0A0P0IX93	Lactobacillus_phage	4.0e-17	61.4
AYC74397.1\|1122986_1123703_+	phage regulatory protein	D2IYT0	Enterococcus_phage	5.1e-65	59.9
AYC74398.1\|1123714_1123924_+	hypothetical protein	NA	NA	NA	NA
AYC74399.1\|1124039_1124366_-	RNA polymerase III	E9LUT2	Lactobacillus_phage	2.7e-53	98.1
AYC74400.1\|1124423_1124684_+	hypothetical protein	NA	NA	NA	NA
AYC74401.1\|1124826_1125081_+	hypothetical protein	NA	NA	NA	NA
AYC74402.1\|1125083_1125284_+	hypothetical protein	E9LUT7	Lactobacillus_phage	1.0e-26	89.4
AYC74403.1\|1125737_1125995_+	hypothetical protein	NA	NA	NA	NA
AYC74404.1\|1126097_1126841_+	replisome organizer	E9LUM6	Lactobacillus_phage	2.7e-40	57.3
AYC74405.1\|1126840_1127626_+	ATP-binding protein	E9LUN6	Lactobacillus_phage	4.1e-132	91.2
AYC74406.1\|1127761_1128064_+	hypothetical protein	E9LUN7	Lactobacillus_phage	1.0e-46	93.0
AYC74407.1\|1128066_1128378_+	hypothetical protein	A0A2P0ZLB4	Lactobacillus_phage	1.1e-45	87.4
AYC74408.1\|1128381_1128576_+	hypothetical protein	A0A2P0ZLB7	Lactobacillus_phage	4.5e-16	71.4
AYC74409.1\|1128568_1128727_+	hypothetical protein	A0A2P0ZLB5	Lactobacillus_phage	3.9e-18	92.3
AYC74410.1\|1128731_1129802_+	DNA cytosine methyltransferase	A0A1I9KKE7	Lactobacillus_phage	5.6e-124	61.3
AYC74411.1\|1130243_1130669_+	transcriptional regulator	E9LUP5	Lactobacillus_phage	7.2e-67	87.2
AYC74412.1\|1131720_1132644_+	hypothetical protein	NA	NA	NA	NA
AYC74413.1\|1132726_1132906_+	hypothetical protein	E9LUP6	Lactobacillus_phage	3.6e-12	66.1
AYC74414.1\|1132874_1133387_+	HNH endonuclease	E9LUP7	Lactobacillus_phage	2.4e-80	91.7
AYC74415.1\|1133606_1134068_+\|terminase	phage terminase small subunit P27 family	A0A286QRF4	Streptococcus_phage	3.2e-44	57.5
AYC76268.1\|1134054_1135962_+\|terminase	terminase large subunit	E9LUP9	Lactobacillus_phage	2.6e-180	49.8
AYC74416.1\|1135951_1136146_+	DUF1056 family protein	E9LUQ0	Lactobacillus_phage	3.8e-23	89.1
AYC74417.1\|1136148_1137345_+\|portal	phage portal protein	E9LUQ1	Lactobacillus_phage	2.2e-206	90.2
AYC74418.1\|1137322_1138081_+\|protease	Clp protease ClpP	E9LUQ2	Lactobacillus_phage	5.5e-126	94.0
AYC74419.1\|1138080_1139313_+\|capsid	phage major capsid protein	E9LUQ3	Lactobacillus_phage	5.0e-209	91.9
AYC74420.1\|1139385_1139724_+\|head,tail	phage gp6-like head-tail connector protein	E9LUQ4	Lactobacillus_phage	7.0e-57	100.0
AYC74421.1\|1139707_1140070_+\|head,tail	head-tail adaptor protein	E9LUQ5	Lactobacillus_phage	5.2e-66	100.0
AYC74422.1\|1140059_1140500_+\|tail	phage tail protein	E9LUQ6	Lactobacillus_phage	5.0e-79	99.3
AYC74423.1\|1140496_1140880_+	hypothetical protein	E9LUQ7	Lactobacillus_phage	9.4e-66	98.4
AYC74424.1\|1140880_1141519_+\|tail	phage tail protein	E9LUQ8	Lactobacillus_phage	1.1e-116	99.5
AYC74425.1\|1141720_1142104_+	hypothetical protein	E9LUQ9	Lactobacillus_phage	7.4e-63	97.6
AYC74426.1\|1142100_1142292_+	hypothetical protein	E9LUR0	Lactobacillus_phage	1.5e-27	100.0
AYC74427.1\|1142304_1147473_+\|tail	phage tail protein	E9LUR1	Lactobacillus_phage	0.0e+00	98.0
AYC74428.1\|1147544_1149317_+\|tail	phage tail protein	E9LUR2	Lactobacillus_phage	0.0e+00	97.3
AYC74429.1\|1149380_1151750_+	hypothetical protein	E9LUR3	Lactobacillus_phage	0.0e+00	96.1
AYC74430.1\|1151766_1154532_+\|tail	phage tail protein	A0A2P0ZL34	Lactobacillus_phage	1.8e-195	50.4
AYC74431.1\|1154524_1154779_+	hypothetical protein	E9LUR5	Lactobacillus_phage	1.4e-30	100.0
AYC74432.1\|1154927_1155812_+	hypothetical protein	E9LUR7	Lactobacillus_phage	1.7e-139	99.7
AYC74433.1\|1155827_1157000_+	LysM peptidoglycan-binding domain-containing protein	E9LUR8	Lactobacillus_phage	3.1e-216	100.0
AYC74434.1\|1156999_1157263_+\|holin	holin	E9LUR9	Lactobacillus_phage	2.0e-38	100.0
AYC74435.1\|1157275_1157806_+\|holin	holin	E9LUS0	Lactobacillus_phage	2.9e-41	100.0
AYC74436.1\|1159046_1160258_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
AYC74437.1\|1160736_1162479_+	ABC transporter permease subunit	NA	NA	NA	NA
AYC74438.1\|1162497_1163289_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.5e-30	36.8
AYC74439.1\|1163269_1164454_+	LytR family transcriptional regulator	NA	NA	NA	NA
AYC74440.1\|1164605_1165178_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AYC74441.1\|1165929_1166871_-	glycosyltransferase	V9QJB1	Oenococcus_phage	2.4e-78	49.0
AYC74442.1\|1167316_1167709_-	hypothetical protein	NA	NA	NA	NA
AYC74443.1\|1167872_1168265_+	hypothetical protein	NA	NA	NA	NA
AYC74444.1\|1168300_1169470_+	hydroxymethylglutaryl-CoA synthase	NA	NA	NA	NA
AYC74445.1\|1169519_1170149_-	hypothetical protein	NA	NA	NA	NA
AYC74446.1\|1170543_1170684_+	hypothetical protein	NA	NA	NA	NA
AYC74447.1\|1170773_1171406_-	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	2.3e-16	56.2
AYC74448.1\|1171557_1171797_+	DUF896 domain-containing protein	NA	NA	NA	NA
AYC74449.1\|1171894_1172131_+	YneF family protein	NA	NA	NA	NA
AYC74450.1\|1172187_1172823_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
AYC74451.1\|1172934_1173693_+\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
AYC74452.1\|1173676_1173982_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
AYC74453.1\|1174066_1175065_+	D-2-hydroxyacid dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	2.3e-47	34.9
AYC74454.1\|1175353_1176076_-	HAD family hydrolase	NA	NA	NA	NA
AYC74455.1\|1176300_1177104_+	30S ribosomal protein S2	NA	NA	NA	NA
AYC74456.1\|1177206_1178085_+	elongation factor Ts	NA	NA	NA	NA
1177306:1177323	attR	NA	NA	NA	NA
AYC74457.1\|1178285_1179008_+	UMP kinase	NA	NA	NA	NA
AYC74458.1\|1179009_1179573_+	ribosome-recycling factor	NA	NA	NA	NA
AYC74459.1\|1179692_1180472_+	ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	R9W0U9	Flavobacterium_phage	1.1e-23	43.1
AYC74460.1\|1180487_1181273_+	CDP-archaeol synthase	NA	NA	NA	NA
AYC74461.1\|1181310_1182588_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
AYC74462.1\|1182627_1184337_+\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
AYC74463.1\|1184830_1189144_+	DNA polymerase III subunit alpha	A0A1X9SH08	Bradyrhizobium_phage	1.0e-14	34.0
AYC74464.1\|1189439_1189916_+	ribosome maturation factor RimP	NA	NA	NA	NA
AYC74465.1\|1189936_1191154_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
AYC74466.1\|1191198_1191498_+	YlxR family protein	NA	NA	NA	NA
AYC74467.1\|1191487_1191793_+	hypothetical protein	NA	NA	NA	NA
AYC74468.1\|1191807_1194384_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	9.6e-21	23.3
AYC74469.1\|1194406_1194760_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
AYC74470.1\|1195408_1196863_+	MFS transporter	NA	NA	NA	NA
AYC74471.1\|1196855_1198025_+	chorismate synthase	NA	NA	NA	NA
AYC74472.1\|1198033_1198561_+	amino acid biosynthesis protein	NA	NA	NA	NA
AYC74473.1\|1198574_1199873_+	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
AYC74474.1\|1199875_1200973_+	prephenate dehydrogenase	NA	NA	NA	NA
AYC74475.1\|1200975_1201497_+	shikimate kinase	NA	NA	NA	NA
AYC74476.1\|1201981_1202905_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA

DBSCAN-SWA_4

1695446 : 1708224

Lactobacillus_phage(70.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYC74940.1\|1695446_1696391_-	glycosyltransferase	V5USA4	Oenococcus_phage	2.0e-72	45.5
AYC74941.1\|1696415_1697081_-	phosphatase PAP2 family protein	NA	NA	NA	NA
AYC74942.1\|1697790_1698483_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	5.3e-35	37.6
AYC74943.1\|1698466_1699843_+	sensor histidine kinase	W8CYF6	Bacillus_phage	3.4e-25	31.0
AYC74944.1\|1700000_1700138_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
AYC74945.1\|1700233_1700674_+	nucleoside 2-deoxyribosyltransferase	A0A2P0ZL88	Lactobacillus_phage	1.2e-75	97.9
AYC74946.1\|1700744_1701305_-	hypothetical protein	A0A2P0ZL75	Lactobacillus_phage	6.5e-100	98.4
AYC74947.1\|1701392_1703831_-	flavocytochrome c	A0A2P0ZL82	Lactobacillus_phage	0.0e+00	99.6
AYC74948.1\|1703833_1704448_-	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	6.3e-112	100.0
AYC74949.1\|1704500_1704830_+	hypothetical protein	NA	NA	NA	NA
AYC74950.1\|1704790_1705738_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	2.7e-178	100.0
AYC74951.1\|1705923_1706895_+	peptidase S41	A0A2P0ZL68	Lactobacillus_phage	3.5e-181	98.5
AYC74952.1\|1706985_1708224_-	hypothetical protein	A0A2P0ZL72	Lactobacillus_phage	2.4e-219	98.7

DBSCAN-SWA_5

2354923 : 2363547

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYC75502.1\|2354923_2355919_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	2.0e-51	38.5
AYC75503.1\|2356057_2356843_-	acyl-ACP thioesterase	NA	NA	NA	NA
AYC75504.1\|2356846_2357743_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	4.4e-82	55.7
AYC75505.1\|2357841_2358189_-	initiation-control protein YabA	M1PFV3	Streptococcus_phage	2.4e-12	33.3
AYC75506.1\|2358213_2359233_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-32	33.5
AYC75507.1\|2359249_2359579_-	hypothetical protein	NA	NA	NA	NA
AYC75508.1\|2359575_2360241_-	dTMP kinase	M1PSC7	Streptococcus_phage	1.4e-53	52.7
AYC75509.1\|2360638_2360890_-	DUF2508 family protein	NA	NA	NA	NA
AYC75510.1\|2360904_2361504_-	recombination protein RecR	NA	NA	NA	NA
AYC75511.1\|2361519_2361828_-	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
AYC75512.1\|2361849_2363547_-	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	3.9e-55	37.0

DBSCAN-SWA_6

2497035 : 2550813

uncultured_Mediterranean_phage(22.22%)

protease,bacteriocin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYC75625.1\|2497035_2498307_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	4.5e-96	43.7
AYC75626.1\|2498773_2500387_-	CTP synthetase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.2e-143	49.9
AYC75627.1\|2500559_2501168_-	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
AYC75628.1\|2501212_2501653_-	DUF1934 domain-containing protein	NA	NA	NA	NA
AYC75629.1\|2502015_2502948_+	lipoate--protein ligase family protein	NA	NA	NA	NA
AYC75630.1\|2502962_2504315_+	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	5.2e-26	32.9
AYC75631.1\|2504334_2505144_+	sugar-phosphatase	NA	NA	NA	NA
AYC75632.1\|2505313_2506300_-	hypothetical protein	NA	NA	NA	NA
AYC75633.1\|2506382_2507405_-	YdcF family protein	NA	NA	NA	NA
AYC75634.1\|2507693_2508674_-	ribose-phosphate diphosphokinase	A0A2K9L8D8	Tupanvirus	4.9e-42	36.3
AYC75635.1\|2509039_2509864_-	serine hydrolase	NA	NA	NA	NA
AYC75636.1\|2510099_2511482_-	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase	A0A2K9L140	Tupanvirus	7.4e-28	33.2
AYC75637.1\|2511550_2512387_-	pur operon repressor	NA	NA	NA	NA
AYC75638.1\|2512742_2513546_-	metal ABC transporter permease	NA	NA	NA	NA
AYC75639.1\|2513532_2514231_-	ABC transporter ATP-binding protein	A0A1V0SGN0	Hokovirus	1.2e-15	27.8
AYC75640.1\|2514499_2515444_-	alpha/beta hydrolase	NA	NA	NA	NA
AYC75641.1\|2515489_2515672_+	hypothetical protein	NA	NA	NA	NA
AYC75642.1\|2515753_2516620_-	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	NA	NA	NA	NA
AYC75643.1\|2516752_2517004_-	hypothetical protein	NA	NA	NA	NA
AYC75644.1\|2517108_2517999_-	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
AYC75645.1\|2517995_2518559_-	ribonuclease M5	NA	NA	NA	NA
AYC75646.1\|2518545_2519322_-	TatD family deoxyribonuclease	NA	NA	NA	NA
AYC75647.1\|2519444_2520377_-	MFS transporter	NA	NA	NA	NA
AYC75648.1\|2520609_2522661_-\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	2.7e-90	35.8
AYC75649.1\|2522982_2523372_-	NUDIX domain-containing protein	NA	NA	NA	NA
AYC75650.1\|2523966_2524809_-	DUF72 domain-containing protein	NA	NA	NA	NA
AYC75651.1\|2524808_2525513_-	NAD-dependent protein deacetylase	NA	NA	NA	NA
AYC75652.1\|2525534_2526494_-	IpaB/EvcA family protein	NA	NA	NA	NA
AYC75653.1\|2526486_2527761_-	hydroxymethylglutaryl-CoA reductase, degradative	NA	NA	NA	NA
AYC75654.1\|2527806_2528724_-	Ppx/GppA family phosphatase	NA	NA	NA	NA
AYC75655.1\|2529165_2530179_-\|tRNA	tRNA-dihydrouridine synthase family protein	NA	NA	NA	NA
AYC75656.1\|2530291_2531038_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
AYC75657.1\|2531187_2532084_-	ROK family protein	NA	NA	NA	NA
AYC75658.1\|2532164_2533601_-	glycosyl hydrolase family protein	A0A0B5JD41	Pandoravirus	1.3e-30	25.5
AYC76292.1\|2533618_2534974_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
AYC75659.1\|2535196_2535619_-	DUF3284 domain-containing protein	NA	NA	NA	NA
AYC75660.1\|2535608_2535797_-	hypothetical protein	NA	NA	NA	NA
AYC75661.1\|2535803_2537165_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
AYC75662.1\|2537237_2537948_-	GntR family transcriptional regulator	NA	NA	NA	NA
AYC75663.1\|2538353_2539370_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
AYC75664.1\|2539808_2540585_-	carbon-nitrogen family hydrolase	NA	NA	NA	NA
AYC75665.1\|2540843_2543153_+	ATP-dependent DNA helicase	NA	NA	NA	NA
AYC75666.1\|2543247_2543451_-	hypothetical protein	NA	NA	NA	NA
AYC75667.1\|2543588_2544275_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AYC75668.1\|2544368_2545049_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AYC75669.1\|2545135_2545804_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AYC75670.1\|2545871_2546561_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AYC75671.1\|2546650_2548027_-	HlyD family secretion protein	NA	NA	NA	NA
AYC75672.1\|2548043_2550194_-	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	3.6e-45	27.9
AYC75673.1\|2550459_2550630_+\|bacteriocin	two-peptide bacteriocin plantaricin EF subunit PlnE	NA	NA	NA	NA
AYC75674.1\|2550654_2550813_+\|bacteriocin	two-peptide bacteriocin plantaricin EF subunit PlnF	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP032465

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2291 : 53081

Streptococcus_phage(20.0%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYC76306.1\|2291_2552_+\|transposase	transposase	A0A1P8CWP5	Bacillus_phage	4.2e-09	39.3
AYC76307.1\|2548_3367_+\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	1.1e-31	35.3
AYC76361.1\|3612_3774_+	LtrC-like protein	NA	NA	NA	NA
AYC76308.1\|3912_4017_-\|holin	putative holin-like toxin	NA	NA	NA	NA
AYC76309.1\|4556_5355_+\|transposase	IS5 family transposase	NA	NA	NA	NA
AYC76310.1\|5489_6017_+	hypothetical protein	NA	NA	NA	NA
AYC76311.1\|6124_6718_+	recombinase family protein	M4QQC6	Vibrio_phage	4.6e-19	42.4
AYC76312.1\|6814_7621_+	ParA family protein	A0A1V0DZZ0	Clostridioides_phage	2.3e-21	30.1
AYC76313.1\|7634_7883_+	hypothetical protein	NA	NA	NA	NA
AYC76314.1\|8485_9565_+	plasmid replication initiation protein	NA	NA	NA	NA
AYC76315.1\|9791_10073_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
AYC76316.1\|10119_10305_+	hypothetical protein	NA	NA	NA	NA
AYC76317.1\|10301_10982_+	ATPase	NA	NA	NA	NA
AYC76318.1\|10971_11250_-	hypothetical protein	NA	NA	NA	NA
AYC76319.1\|11272_11482_-	hypothetical protein	NA	NA	NA	NA
AYC76320.1\|11751_13812_+	nickase	NA	NA	NA	NA
AYC76362.1\|13840_15445_+	type IA DNA topoisomerase	A0A1X9I6W8	Streptococcus_phage	1.9e-107	46.0
AYC76321.1\|15567_15783_+	hypothetical protein	NA	NA	NA	NA
AYC76322.1\|15786_16911_+	hypothetical protein	NA	NA	NA	NA
AYC76323.1\|17184_18282_+	nucleotidyltransferase	NA	NA	NA	NA
AYC76324.1\|18291_18720_+	hypothetical protein	NA	NA	NA	NA
AYC76325.1\|18716_19559_+	hypothetical protein	NA	NA	NA	NA
AYC76326.1\|19707_19917_-	hypothetical protein	NA	NA	NA	NA
AYC76327.1\|20108_20213_-\|holin	putative holin-like toxin	NA	NA	NA	NA
AYC76328.1\|20555_21176_+	hypothetical protein	NA	NA	NA	NA
AYC76329.1\|21383_22183_-\|transposase	IS5 family transposase	NA	NA	NA	NA
AYC76330.1\|22726_23113_+	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
AYC76331.1\|23244_24609_+	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	1.5e-09	22.6
AYC76363.1\|26206_26284_-	hypothetical protein	NA	NA	NA	NA
AYC76364.1\|26386_26710_+	ArsR family transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	5.2e-17	42.7
AYC76332.1\|26758_28492_+	arsenical pump-driving ATPase	NA	NA	NA	NA
AYC76333.1\|28534_29830_+	arsenical efflux pump membrane protein ArsB	A0A2H4PQU3	Staphylococcus_phage	2.0e-144	61.9
AYC76334.1\|29866_30202_+	arsenical resistance operon transcriptional repressor ArsD	NA	NA	NA	NA
AYC76335.1\|30224_30641_+	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	3.9e-33	56.9
AYC76336.1\|30808_31024_+	hypothetical protein	NA	NA	NA	NA
AYC76337.1\|33001_34849_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.3e-59	28.9
AYC76338.1\|35167_35428_+\|transposase	transposase	A0A1P8CWP5	Bacillus_phage	4.2e-09	39.3
AYC76339.1\|35424_36243_+\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	1.1e-31	35.3
AYC76365.1\|36488_36650_+	LtrC-like protein	NA	NA	NA	NA
AYC76340.1\|36788_36893_-\|holin	putative holin-like toxin	NA	NA	NA	NA
AYC76341.1\|37432_38231_+\|transposase	IS5 family transposase	NA	NA	NA	NA
AYC76342.1\|38365_38893_+	hypothetical protein	NA	NA	NA	NA
AYC76343.1\|39000_39594_+	recombinase family protein	M4QQC6	Vibrio_phage	4.6e-19	42.4
AYC76344.1\|39690_40497_+	ParA family protein	A0A1V0DZZ0	Clostridioides_phage	2.3e-21	30.1
AYC76345.1\|40510_40759_+	hypothetical protein	NA	NA	NA	NA
AYC76346.1\|41361_42441_+	plasmid replication initiation protein	NA	NA	NA	NA
AYC76347.1\|42667_42949_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
AYC76348.1\|42995_43181_+	hypothetical protein	NA	NA	NA	NA
AYC76349.1\|43177_43858_+	ATPase	NA	NA	NA	NA
AYC76350.1\|43847_44126_-	hypothetical protein	NA	NA	NA	NA
AYC76351.1\|44148_44358_-	hypothetical protein	NA	NA	NA	NA
AYC76366.1\|46715_48320_+	type IA DNA topoisomerase	A0A1X9I6W8	Streptococcus_phage	1.9e-107	46.0
AYC76352.1\|48442_48658_+	hypothetical protein	NA	NA	NA	NA
AYC76353.1\|48661_49786_+	hypothetical protein	NA	NA	NA	NA
AYC76354.1\|50058_50646_+	nucleotidyltransferase	NA	NA	NA	NA
AYC76355.1\|50621_51155_+	hypothetical protein	NA	NA	NA	NA
AYC76356.1\|51164_51593_+	hypothetical protein	NA	NA	NA	NA
AYC76357.1\|51971_52376_+	hypothetical protein	NA	NA	NA	NA
AYC76358.1\|52567_52801_-	hypothetical protein	NA	NA	NA	NA
AYC76359.1\|52976_53081_-\|holin	putative holin-like toxin	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP032464

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP032465

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection