CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
CP022965	Salmonella enterica subsp. enterica serovar Pullorum strain QJ-2D-Sal plasmid pQJDsal2, complete sequence	0 crisprs	cas14j	0	1
CP022963	Salmonella enterica subsp. enterica serovar Pullorum strain QJ-2D-Sal chromosome, complete genome	2 crisprs	DEDDh,cas3,DinG,WYL,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	3	6
CP022964	Salmonella enterica subsp. enterica serovar Pullorum strain QJ-2D-Sal plasmid pQJDsal1, complete sequence	0 crisprs	csa3	0	4

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

77585 : 85291

Vibrio_phage(16.67%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYE25985.1\|77585_78266_-	DNA methylase	A0A2I7RE86	Vibrio_phage	2.4e-27	36.0
AYE25986.1\|78647_79004_-	hypothetical protein	NA	NA	NA	NA
AYE25987.1\|78996_79467_-	hypothetical protein	NA	NA	NA	NA
AYE25988.1\|79977_80400_+	protein SamA	A0A1W6JNS2	Morganella_phage	1.0e-28	51.6
AYE25989.1\|80399_81674_+	DNA polymerase V subunit UmuC	F1C5A5	Cronobacter_phage	8.6e-156	64.2
AYE25990.1\|81755_82733_-	chromosome partitioning protein ParB	A0A1B0V750	Salmonella_phage	1.5e-83	53.2
AYE25991.1\|82729_83935_-	ParA family protein	A0A077SL49	Escherichia_phage	1.5e-162	69.3
AYE25992.1\|84349_85291_+\|transposase	ISNCY family transposase	Q2A0A7	Sodalis_phage	2.0e-72	54.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP022963

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CRISPR-Cas detection and classification

Crispr_ID: CP022963_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022963_1

4048046-4048258

TypeI-E

I-E

Consensus_repeat	Method
CCGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CCGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
CCGGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR

3 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of CP022963_1

>merge|CP022963|1|4048046-4048258|CRISPRCasFinder,CRT,PILER-CR
CGTGTTTATCCCCGCTGACGCGGGGAACACTATTTATAAGCGTGTCATCTATGCAACCCAACCGGTTTATCCCCGCTGGCGCGGGGAACACGGCCGCTGGTCAAATTCCCAATCTGAGCAATCCGGTTTATCCCCGCTGGCGCGGGGAACACATAGCCCCGGCAGCGATAGCTAAACCAGTTCCCGGTTTATCCCCGCTGGCGCGGGGAACAC

>CP022963|1|1|4048046-4048258|CRISPRCasFinder
CGTGTTTATCCCCGCTGACGCGGGGAACAC	TATTTATAAGCGTGTCATCTATGCAACCCAA
CCGGTTTATCCCCGCTGGCGCGGGGAACAC	GGCCGCTGGTCAAATTCCCAATCTGAGCAAT
CCGGTTTATCCCCGCTGGCGCGGGGAACAC	ATAGCCCCGGCAGCGATAGCTAAACCAGTTC
CCGGTTTATCCCCGCTGGCGCGGGGAACAC

>CP022963|1|1|4048046-4048258|CRT
CGTGTTTATCCCCGCTGACGCGGGGAACAC	TATTTATAAGCGTGTCATCTATGCAACCCAA
CCGGTTTATCCCCGCTGGCGCGGGGAACAC	GGCCGCTGGTCAAATTCCCAATCTGAGCAAT
CCGGTTTATCCCCGCTGGCGCGGGGAACAC	ATAGCCCCGGCAGCGATAGCTAAACCAGTTC
CCGGTTTATCCCCGCTGGCGCGGGGAACAC

>CP022963|1|1|4048107-4048258|PILER-CR
CCGGTTTATCCCCGCTGGCGCGGGGAACAC	GGCCGCTGGTCAAATTCCCAATCTGAGCAAT
CCGGTTTATCCCCGCTGGCGCGGGGAACAC	ATAGCCCCGGCAGCGATAGCTAAACCAGTTC
CCGGTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
CP022963.1\|AYE25800.1\|4056929_4057136_+\|hypothetical-protein	unknown	unknown	unknown
CP022963.1\|AYE25049.1\|4052576_4054133_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
CP022963.1\|AYE25047.1\|4050953_4052012_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
CP022963.1\|AYE25039.1\|4043785_4044391_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
CP022963.1\|AYE25037.1\|4042909_4043221_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
CP022963.1\|AYE25046.1\|4050196_4050943_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
CP022963.1\|AYE25044.1\|4048647_4049568_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
CP022963.1\|AYE25040.1\|4044377_4045817_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
CP022963.1\|AYE25042.1\|4046985_4048032_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
CP022963.1\|AYE25034.1\|4040655_4041705_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
CP022963.1\|AYE25050.1\|4054144_4056808_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
CP022963.1\|AYE25048.1\|4052025_4052580_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
CP022963.1\|AYE25043.1\|4048354_4048648_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
CP022963.1\|AYE25035.1\|4041701_4042181_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
CP022963.1\|AYE25045.1\|4049564_4050215_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
CP022963.1\|AYE25041.1\|4045826_4046735_-\|sulfate-adenylyltransferase-subunit-2	unknown	unknown	gnl\|CDD\|235375
CP022963.1\|AYE25051.1\|4058283_4059018_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
CP022963.1\|AYE25036.1\|4042180_4042891_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
CP022963.1\|AYE25038.1\|4043411_4043768_-\|DUF3561-domain-containing-protein	unknown	unknown	gnl\|CDD\|371891
CP022963.1\|AYE25033.1\|4039913_4040675_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732

Protein	Function_ID	Function_description	E-value
CP022963.1\|AYE25049.1\|4052576_4054133_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
CP022963.1\|AYE25047.1\|4050953_4052012_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	4.28543e-133
CP022963.1\|AYE25039.1\|4043785_4044391_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	5.05843e-145
CP022963.1\|AYE25037.1\|4042909_4043221_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	1.08865e-64
CP022963.1\|AYE25046.1\|4050196_4050943_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	5.23137e-48
CP022963.1\|AYE25044.1\|4048647_4049568_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.63116e-157
CP022963.1\|AYE25040.1\|4044377_4045817_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
CP022963.1\|AYE25042.1\|4046985_4048032_+\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
CP022963.1\|AYE25034.1\|4040655_4041705_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
CP022963.1\|AYE25050.1\|4054144_4056808_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
CP022963.1\|AYE25048.1\|4052025_4052580_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.26497e-33
CP022963.1\|AYE25043.1\|4048354_4048648_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	1.1867e-62
CP022963.1\|AYE25035.1\|4041701_4042181_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	3.84083e-103
CP022963.1\|AYE25045.1\|4049564_4050215_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	6.63277e-74
CP022963.1\|AYE25041.1\|4045826_4046735_-\|sulfate-adenylyltransferase-subunit-2	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
CP022963.1\|AYE25051.1\|4058283_4059018_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.31774e-138
CP022963.1\|AYE25036.1\|4042180_4042891_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	4.09575e-119
CP022963.1\|AYE25038.1\|4043411_4043768_-\|DUF3561-domain-containing-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	3.34072e-48
CP022963.1\|AYE25033.1\|4039913_4040675_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.7078e-146

>CP022963.1|AYE25042.1|4046985_4048032_+|aminopeptidase
MFSATRRFAVILALGVGFILPAQAASPGPGEIANTQARHIATFFPGRMTDSPAEMLSADYLRQQFTQMGYQSDIRTFNSLFIYTTKDNRKNWHNVTGSTVIAAHEGRVPQQIIIMAHLDTYAPQSDADVDANLGGLTLQGMDDNAAGLGVMLELAARLKDIPTHYGIRFIATSGEEEGKLGAENLLKRMSDAEKKNTLLVINLDNLIVGDKLYFNSGKNTPEAVRTLTRDRALAIARRYGIAANTNPGRNPSYPKGTGCCNDAEVFDKAGISVLSVEATNWNLGKKDGYQQRVKNASFPNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIMLPLVKELAKAEKTS
>CP022963.1|AYE25041.1|4045826_4046735_-|sulfate-adenylyltransferase-subunit-2
MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
>CP022963.1|AYE25040.1|4044377_4045817_-|sulfate-adenylyltransferase-subunit-CysN
MNTILAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYCEETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSSPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
>CP022963.1|AYE25039.1|4043785_4044391_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRYGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
>CP022963.1|AYE25038.1|4043411_4043768_-|DUF3561-domain-containing-protein
MPGMVKVTGFNMRNSHNITFTRSDAFMVDDDATSAFPGAVVGFVSWLLALGSPFLLYGPNTLFFFLYTWPFFLALMPVSVIIGIALHLLVKGKILFSIMFTLLAVGALFGALFIWLLG
>CP022963.1|AYE25037.1|4042909_4043221_-|cell-division-protein-FtsB
MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
>CP022963.1|AYE25036.1|4042180_4042891_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAKAQWVLVHDAARPCLHQDDLARLLTISENSRVGGILASPVRDTMKRGEPGKNAIAHTVERADLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPALVEGRADNIKVTRPEDLALAEFYLTRTIHQEKA
>CP022963.1|AYE25035.1|4041701_4042181_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRISYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
>CP022963.1|AYE25034.1|4040655_4041705_-|tRNA-pseudouridine(13)-synthase-TruD
MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFDGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQEAVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
>CP022963.1|AYE25033.1|4039913_4040675_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW
>CP022963.1|AYE25043.1|4048354_4048648_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAVWLLEVRAGVYVGDTSKRIREMIWQQITQLGGVGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVENQ
>CP022963.1|AYE25044.1|4048647_4049568_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLNPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLASTVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALDDDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRATYALLAKQYGVKWHGRNYDPKDWEKGDVVNRCISAATSCLYGISEAAILAAGYAPAIGFIHSGKPLSFVYDIADIIKFESVVPKAFEIAARHPAEPDKEVRLACRDIFRSSKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPESLGDSGHRGHG
>CP022963.1|AYE25045.1|4049564_4050215_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTSELSPAQLLHLVERGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQEQPAASTIFDVQTRPFAPMLSAGQTLRFNLRANPTICKNGKRHDLLMEAKRQRKTQGDSQDIWSYQQQAALEWLARQGEQNGFTLREASVDAYRQQQIRREKSRQMIQFSSVDYTGVLVINEPALFLQRLAQGYGKSWAFGCGMMMIKPGDDA
>CP022963.1|AYE25046.1|4050196_4050943_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDEEERLNTFNRHYQFLLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRDYYTDAWWMIAVSATPDAPYTLAQLQAALQHPVFPLYLGRKSHPLALPLAPQLLEGNAADVLREAYRWYQDQFNALKLTLPGLQNECWWEGEHDGLTANKILRRRDMPLSRQQWLFGERSVNQGPWLRKEDACISQE
>CP022963.1|AYE25047.1|4050953_4052012_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRISSQSLKRAWRTSELFEQALAGHIGIRTGRIAREAAQILVDSGIDAKKAVEYVKNIANCFGKVKEDKKPKDELTNAETEQLVHISPAEFEAVKALARRLAEEKRPATEEEAELLRHDRMAVDIAMFGRMLAKKTDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNGNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITALHENMNEVYAQETAFKNFNVMNQQGSMKDVLDFICA
>CP022963.1|AYE25048.1|4052025_4052580_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSVVTKDDKATLRQWHDELQEKRGLRASLRRSKTVNDACLAEGLHSLLMQTHSLWKNKAPWNVTALAITAALAAHIKFIDEQKSFAAQLGQKKGGDTPVMSKLRFSHLLAVKTPDELLRQLRRAVKLLDGSVNLFSLADDIFCWCQEQNDLLNHHRRQQRPTEFLRIRWALEYYQAGDTDNEQD
>CP022963.1|AYE25049.1|4052576_4054133_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVDLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKRYKNWEDIWFDGLHADVLHKALAPLEHAFQFGAESPSFMQDFEPLSGEKVSIASLLPEIPGAQTTKFNKDHFVKRGVTERFCPHCAALALFSLQLNAPAGGKGYRTGLRGGGPLTTLVELQEYQGERQTPIWRKLWLNVMPQDTADLPLSDQCDATVFPWLAATRTSEQANAVTTPEQVNKLQAYWGMPRRIRLDFATLQSGCCDICGAESDELLGFMTVKNYGVNYDGWRHPLTPYRAPVKDQNAFFSVKPQPGGLIWRDWLGLSQNNQTEANYESPAQVVKVFNARSLTDVKAGIRGFGADFDNMKIRCWYEHHFPLLMTEGLIPDLRKAVQTAARLLSLLRSALKEAWFTNAKDARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>CP022963.1|AYE25050.1|4054144_4056808_-|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPYSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERCVDIGWLHSEEACLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQEGKFYCDRAFAGQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDSVVTPYASGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDFAACGYSANEGLIGMMGE
>CP022963.1|AYE25800.1|4056929_4057136_+|hypothetical-protein
MFFINIYPTNNYYKFFRLFLLEEALKEASSNAFCINQNLKKTTICGESSTFCLNYRHHKGLPTINVLY
>CP022963.1|AYE25051.1|4058283_4059018_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRVLALAETNAQLKTLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG

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Crispr_ID: CP022963_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022963_2

4064401-4064734

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
GTTTATCCCCGCTGGCGCGGGGAACAC	CRT
GTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR

5 spacers

cas3,cas8e

The CRISPR arrays of CP022963_2

>merge|CP022963|2|4064401-4064734|CRISPRCasFinder,CRT,PILER-CR
ACGGCTATCCTTGTTGGCGCGGGGAACACGGCTACACGCAAAAATTCCAGTCGTTGGCGCACGGTTTATCCCCGCTGGCGCGGGGAACACGTGGCCGGGTTGAGTACCGATCGCATTTTTTTCGGTTTATCCCCGCTGGCGCGGGGAACACTTCCCCTCCGGATGGCGGGGATGCTCTTATGGCGGTTTATCCCCGCTGGCGCGGGGAACACAATAATCGGCAATTTGTCCTGGACAGGCACGGCAGTTTATCCCCGCTGGCGCGGGGAACACGAATCAGGAGGCCAACAGCGCGGCGAAATCCTCAGTTTATCCCCGCTGGCGCGGGGAACAC

>CP022963|2|2|4064401-4064734|CRISPRCasFinder
ACGGCTATCCTTGTTGGCGCGGGGAACAC	GGCTACACGCAAAAATTCCAGTCGTTGGCGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTGGCCGGGTTGAGTACCGATCGCATTTTTTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTCCCCTCCGGATGGCGGGGATGCTCTTATGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AATAATCGGCAATTTGTCCTGGACAGGCACGG
CAGTTTATCCCCGCTGGCGCGGGGAACAC	GAATCAGGAGGCCAACAGCGCGGCGAAATCCT
CAGTTTATCCCCGCTGGCGCGGGGAACAC

>CP022963|2|2|4064403-4064734|CRT
GGCTATCCTTGTTGGCGCGGGGAACAC	GGCTACACGCAAAAATTCCAGTCGTTGGCGCACG
GTTTATCCCCGCTGGCGCGGGGAACAC	GTGGCCGGGTTGAGTACCGATCGCATTTTTTTCG
GTTTATCCCCGCTGGCGCGGGGAACAC	TTCCCCTCCGGATGGCGGGGATGCTCTTATGGCG
GTTTATCCCCGCTGGCGCGGGGAACAC	AATAATCGGCAATTTGTCCTGGACAGGCACGGCA
GTTTATCCCCGCTGGCGCGGGGAACAC	GAATCAGGAGGCCAACAGCGCGGCGAAATCCTCA
GTTTATCCCCGCTGGCGCGGGGAACAC

>CP022963|2|2|4064464-4064734|PILER-CR
GTTTATCCCCGCTGGCGCGGGGAACAC	GTGGCCGGGTTGAGTACCGATCGCATTTTTTTCG
GTTTATCCCCGCTGGCGCGGGGAACAC	TTCCCCTCCGGATGGCGGGGATGCTCTTATGGCG
GTTTATCCCCGCTGGCGCGGGGAACAC	AATAATCGGCAATTTGTCCTGGACAGGCACGGCA
GTTTATCCCCGCTGGCGCGGGGAACAC	GAATCAGGAGGCCAACAGCGCGGCGAAATCCTCA
GTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
CP022963.1\|AYE25059.1\|4069083_4069884_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
CP022963.1\|AYE25052.1\|4059119_4060832_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
CP022963.1\|AYE25049.1\|4052576_4054133_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
CP022963.1\|AYE25057.1\|4065837_4067136_-\|enolase	unknown	unknown	gnl\|CDD\|234617
CP022963.1\|AYE25053.1\|4060831_4062631_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
CP022963.1\|AYE25054.1\|4063054_4063417_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
CP022963.1\|AYE25051.1\|4058283_4059018_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
CP022963.1\|AYE25063.1\|4075177_4075648_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185179
CP022963.1\|AYE25062.1\|4074659_4075163_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185178
CP022963.1\|AYE25050.1\|4054144_4056808_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
CP022963.1\|AYE25802.1\|4062955_4063126_-\|6-pyruvoyl-tetrahydrobiopterin-synthase	unknown	unknown	unknown
CP022963.1\|AYE25064.1\|4075644_4076181_+\|fimbrial-protein-SteF	unknown	unknown	gnl\|CDD\|185168
CP022963.1\|AYE25058.1\|4067218_4068856_-\|CTP-synthetase	unknown	unknown	gnl\|CDD\|235437
CP022963.1\|AYE25065.1\|4076235_4077267_+\|hypothetical-protein	unknown	unknown	unknown
CP022963.1\|AYE25061.1\|4073866_4074640_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185177
CP022963.1\|AYE25800.1\|4056929_4057136_+\|hypothetical-protein	unknown	unknown	unknown
CP022963.1\|AYE25055.1\|4063504_4064302_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224158
CP022963.1\|AYE25060.1\|4070491_4071079_+\|fimbrial-protein-SteA	unknown	unknown	gnl\|CDD\|185169
CP022963.1\|AYE25056.1\|4065030_4065702_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
CP022963.1\|AYE25801.1\|4058944_4059163_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP022963.1\|AYE25059.1\|4069083_4069884_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	3.42454e-158
CP022963.1\|AYE25053.1\|4060831_4062631_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
CP022963.1\|AYE25049.1\|4052576_4054133_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
CP022963.1\|AYE25057.1\|4065837_4067136_-\|enolase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
CP022963.1\|AYE25052.1\|4059119_4060832_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
CP022963.1\|AYE25054.1\|4063054_4063417_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	2.78454e-58
CP022963.1\|AYE25051.1\|4058283_4059018_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.31774e-138
CP022963.1\|AYE25063.1\|4075177_4075648_+\|fimbrial-protein	gnl\|CDD\|185179	PRK15276, PRK15276, putative fimbrial subunit SteE; Provisional.	2.10162e-98
CP022963.1\|AYE25062.1\|4074659_4075163_+\|fimbrial-protein	gnl\|CDD\|185178	PRK15275, PRK15275, putative fimbrial protein SteD; Provisional.	3.31433e-103
CP022963.1\|AYE25050.1\|4054144_4056808_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
CP022963.1\|AYE25064.1\|4075644_4076181_+\|fimbrial-protein-SteF	gnl\|CDD\|185168	PRK15260, PRK15260, fimbrial protein SteF; Provisional.	7.785e-121
CP022963.1\|AYE25061.1\|4073866_4074640_+\|fimbrial-protein	gnl\|CDD\|185177	PRK15274, PRK15274, putative periplasmic fimbrial chaperone protein SteC; Provisional.	0
CP022963.1\|AYE25055.1\|4063504_4064302_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224158	COG1237, COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only].	1.00381e-102
CP022963.1\|AYE25060.1\|4070491_4071079_+\|fimbrial-protein-SteA	gnl\|CDD\|185169	PRK15261, PRK15261, fimbrial protein SteA; Provisional.	5.36845e-100
CP022963.1\|AYE25056.1\|4065030_4065702_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	1.43874e-155
CP022963.1\|AYE25058.1\|4067218_4068856_-\|CTP-synthetase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0

>CP022963.1|AYE25055.1|4063504_4064302_-|MBL-fold-metallo-hydrolase
MALRIRVLLENHKGAGADKSLKARPGLSLLVEDESTSILFDTGPDGSFMQNALAMGIDLSDVSAVVLSHGHYDHCGGVPWLPDNSRIICHPDIARERYAAMTFLGITRKIKKLSCEVDYSRYRMMYTRDPLPIGKNFIWSGEIPVVAPEAYGIFGGHDAEPDSILDEGVLIYQSTKGLVIITGCGHRGIANIVRHCQNITGIKRIYALVGGFHLRCASPFTLWRVRRFLQEQKPEKLCGCHCTGAWGRLWLPEITAPATGDVLRF
>CP022963.1|AYE25054.1|4063054_4063417_+|6-carboxytetrahydropterin-synthase-QueD
MSTTLYKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIMDFADLKAAFKPTYDRLDHYYLNDIPGLSNPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCVYRGE
>CP022963.1|AYE25802.1|4062955_4063126_-|6-pyruvoyl-tetrahydrobiopterin-synthase
MPFRHVRQAVSGFKGEIFIQRGGHDELSGNKKTAVGYRKAHFLSLTKTILRLVTGN
>CP022963.1|AYE25053.1|4060831_4062631_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGYFWGVLNPRSGVVAVTPVPERKMPGVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGAVNDIHTSPYTKDAPLIATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDGKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAEALIGLLRPLTPRLYSIASAQAEVESEVHVTVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPQTPVIMIGPGTGIAPFRAFMQQRAADGAEGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLSRIALAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDARSMAADVEKALLEVIAEFGGMDLESADEYLSELRVERRYQRDVY
>CP022963.1|AYE25052.1|4059119_4060832_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIETLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPLMYQENITEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
>CP022963.1|AYE25801.1|4058944_4059163_+|hypothetical-protein
MVSANASTRSTFGSSFRAFRSSLDISSSRYTLPDGASLIRPTRAVGRIRHLCRHPAIQVIPRNHARDRAPGE
>CP022963.1|AYE25051.1|4058283_4059018_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRVLALAETNAQLKTLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>CP022963.1|AYE25800.1|4056929_4057136_+|hypothetical-protein
MFFINIYPTNNYYKFFRLFLLEEALKEASSNAFCINQNLKKTTICGESSTFCLNYRHHKGLPTINVLY
>CP022963.1|AYE25050.1|4054144_4056808_-|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPYSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERCVDIGWLHSEEACLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQEGKFYCDRAFAGQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDSVVTPYASGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDFAACGYSANEGLIGMMGE
>CP022963.1|AYE25049.1|4052576_4054133_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVDLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKRYKNWEDIWFDGLHADVLHKALAPLEHAFQFGAESPSFMQDFEPLSGEKVSIASLLPEIPGAQTTKFNKDHFVKRGVTERFCPHCAALALFSLQLNAPAGGKGYRTGLRGGGPLTTLVELQEYQGERQTPIWRKLWLNVMPQDTADLPLSDQCDATVFPWLAATRTSEQANAVTTPEQVNKLQAYWGMPRRIRLDFATLQSGCCDICGAESDELLGFMTVKNYGVNYDGWRHPLTPYRAPVKDQNAFFSVKPQPGGLIWRDWLGLSQNNQTEANYESPAQVVKVFNARSLTDVKAGIRGFGADFDNMKIRCWYEHHFPLLMTEGLIPDLRKAVQTAARLLSLLRSALKEAWFTNAKDARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>CP022963.1|AYE25056.1|4065030_4065702_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWDKLSDREVSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGGEPCIHDLMPLTDLLEKSGFSCQIETSGTHEVRCTPNTWVTVSPKVNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLSDDKPRVIALQPISQKEDATRLCIETCIARNWRLSMQTHKYLNIA
>CP022963.1|AYE25057.1|4065837_4067136_-|enolase
MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>CP022963.1|AYE25058.1|4067218_4068856_-|CTP-synthetase
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
>CP022963.1|AYE25059.1|4069083_4069884_-|nucleoside-triphosphate-pyrophosphohydrolase
MTTNHQIDRLLTLMQRLRDPENGCPWDKEQTFASIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFGELSADNSEEALVRWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCSNVGFDWTTLGPVVDKVYEEIDEVMFEARQAVVDQAKLEEEMGDLLFATVNMARHLGTKAELALQKANDKFERRFREVERIVAARGLEMTGVDLETMEEVWQEVKRQEIDL
>CP022963.1|AYE25060.1|4070491_4071079_+|fimbrial-protein-SteA
MKSSHFCKLAVTASLVMGIVSGAQAAGSNTAKVTFLGNIVDSPCSVTLDTEDQTVNMGSSIGNGTLSNGKTTINNARTFHIDLEGCTWATEKNMNVVFTTGSGTTAATGATDNLALMKTDGTGAISNVSLAIGDAGKNNIKLGDTYTQAIADLDGDTILDEKQSLNFTAWLVGAATGTVGTGEFSSAANVTISYL
>CP022963.1|AYE25061.1|4073866_4074640_+|fimbrial-protein
MNKTNHFKRQALIASVLLAAPLVSHSAIVPDRTRVIFNGNENSITVTLKNGNATLPYLAQAWLEDDKFAKDTRYFTALPPLQRIEPKSDGQVKVQPLPTAASLPQDRESLFYFNVREIPPKSDKPNTLQLALQTRIKFFYRPVAVARQVDKTHPWQTKLTLTYQGDGVIFDNPTPFYLVISNAGSKENETASGFKNLLIAPREKVTSPIKGASLGSSPVVGYVDDYGGHRLLVFTCSGNTCKVNEEKTRDAEKKANK
>CP022963.1|AYE25062.1|4074659_4075163_+|fimbrial-protein
MTMLTRWKMLVLLCGGFVTGTEAAGTKTVQLELHLVVTQPPPCTVGGASVEFGDVLTTKVGDASQTKPVGYSLNCDGRASDYLKLQIQGTTTISGEQVLQTSVQGLGIRIQQAGNKQLVPVGITDWLNFTLSGSNGPELEAVPVKEPTTQLAGGDFNASATLVVDYQ
>CP022963.1|AYE25063.1|4075177_4075648_+|fimbrial-protein
MKRVLILTLLITQFACADNLTFHGKLINPPACTINNGEMLEVSFGSVIIDNIDGVNYLTEIPWTLTCDSSFRDDALTFTLSYLGTATPYSAKALTTSVPELGIELQQNGTVFPPGTSLTINESSLPTLKAVPVKQPGKEPAEGDFEAFATLQVDYQ
>CP022963.1|AYE25064.1|4075644_4076181_+|fimbrial-protein-SteF
MNRIFQTAGHLIGGVMLWAVCNTLPAATPNVHYSGKLVAGACNLVVDNDTMATVDFHTIGSDNFDASGQTTPVPFTLSLQDCKTALANGVLVTFQGVEDSTLPGLLALEPSSEASGFAIGVETAAQQPVSINATVGTAFVLKEGITTINLQARLQKYAGEEVMPGEFSGSATVSFEYQ
>CP022963.1|AYE25065.1|4076235_4077267_+|hypothetical-protein
MNQKVLFFLSIIAYPGITQAINQNVMIEPLVIRDSTNYLVLPQAQQAEFSQCKSWPHDSTVIPAKYEATLLNGSLISMFIGGITVNLYTTADVKVNTDAQCTLLNGNFPGYYGITCFVTGYDTDKAVPVRTDNGMSIIESKLYATGTMRYITEIPMDGSGFQGMAIGGAVVINTGAITPTPNTGVISNITMPPLYDPGFIFTVPGCGQYKYHSGTGSVFTNNNSTYTVASPIGFITASLDKNSVLNYNELHYNDKAENIELGKIYLMYKEKNVTWGEGFDYTLENSTINVVCADSRIKTNVDYQCRNGDMGACNNGELGRIIGNWERINVDTNCSVTVILPWQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP022963_1	1.2\|4048137\|31\|CP022963\|CRISPRCasFinder,CRT,PILER-CR	4048137-4048167	31	MK449011	Streptococcus phage Javan92, complete genome	36158-36188	8	0.742
CP022963_1	1.2\|4048137\|31\|CP022963\|CRISPRCasFinder,CRT,PILER-CR	4048137-4048167	31	MK448835	Streptococcus phage Javan93, complete genome	36158-36188	8	0.742
CP022963_1	1.2\|4048137\|31\|CP022963\|CRISPRCasFinder,CRT,PILER-CR	4048137-4048167	31	MK448836	Streptococcus phage Javan95, complete genome	37401-37431	8	0.742
CP022963_1	1.2\|4048137\|31\|CP022963\|CRISPRCasFinder,CRT,PILER-CR	4048137-4048167	31	MK448825	Streptococcus phage Javan639, complete genome	37401-37431	8	0.742
CP022963_1	1.1\|4048076\|31\|CP022963\|CRISPRCasFinder,CRT	4048076-4048106	31	NZ_MG266000	Clostridioides difficile strain 7032985 plasmid pCD-ISS1, complete sequence	5501-5531	9	0.71
CP022963_2	2.5\|4064674\|32\|CP022963\|CRISPRCasFinder	4064674-4064705	32	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	699963-699994	10	0.688

1. spacer 1.2|4048137|31|CP022963|CRISPRCasFinder,CRT,PILER-CR matches to MK449011 (Streptococcus phage Javan92, complete genome) position: , mismatch: 8, identity: 0.742

ggccgctggtcaaattcccaatctgagcaat	CRISPR spacer
tacatcttgacaaattcccaatctgagcgac	Protospacer
 .*  ** * ******************.*.

2. spacer 1.2|4048137|31|CP022963|CRISPRCasFinder,CRT,PILER-CR matches to MK448835 (Streptococcus phage Javan93, complete genome) position: , mismatch: 8, identity: 0.742

ggccgctggtcaaattcccaatctgagcaat	CRISPR spacer
tacatcttgacaaattcccaatctgagcgac	Protospacer
 .*  ** * ******************.*.

3. spacer 1.2|4048137|31|CP022963|CRISPRCasFinder,CRT,PILER-CR matches to MK448836 (Streptococcus phage Javan95, complete genome) position: , mismatch: 8, identity: 0.742

ggccgctggtcaaattcccaatctgagcaat	CRISPR spacer
tacatcttgacaaattcccaatctgagcgac	Protospacer
 .*  ** * ******************.*.

4. spacer 1.2|4048137|31|CP022963|CRISPRCasFinder,CRT,PILER-CR matches to MK448825 (Streptococcus phage Javan639, complete genome) position: , mismatch: 8, identity: 0.742

ggccgctggtcaaattcccaatctgagcaat	CRISPR spacer
tacatcttgacaaattcccaatctgagcgac	Protospacer
 .*  ** * ******************.*.

5. spacer 1.1|4048076|31|CP022963|CRISPRCasFinder,CRT matches to NZ_MG266000 (Clostridioides difficile strain 7032985 plasmid pCD-ISS1, complete sequence) position: , mismatch: 9, identity: 0.71

tatttataagcgtgtcatctatgcaacccaa	CRISPR spacer
aatttataatcatgtcatctatgccataatt	Protospacer
 ******** *.************ *.

6. spacer 2.5|4064674|32|CP022963|CRISPRCasFinder matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.688

gaatcaggaggccaacagcgcggcgaaatcct	CRISPR spacer
gtggtcataggccatcagcgcggcgatatccc	Protospacer
* . . . ****** *********** ****.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

503048 : 564998

Escherichia_phage(57.5%)

portal,integrase,holin,plate,head,lysis,capsid,terminase,tRNA,tail

attL 536264:536306|attR 565863:565905

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYE21910.1\|503048_503486_+\|tRNA	D-aminoacyl-tRNA deacylase	NA	NA	NA	NA
AYE21911.1\|503482_504472_+	acetyltransferase	NA	NA	NA	NA
AYE21912.1\|504486_504933_-	type II toxin-antitoxin system HigA family antitoxin	NA	NA	NA	NA
AYE21913.1\|504929_505241_-	type II toxin-antitoxin system HigB family toxin	NA	NA	NA	NA
AYE21914.1\|505326_506256_-	alpha/beta hydrolase	NA	NA	NA	NA
AYE21915.1\|506473_506785_+	toxin HigB-2	NA	NA	NA	NA
AYE25666.1\|506821_507076_+	transcriptional regulator	NA	NA	NA	NA
AYE21916.1\|507122_508052_-	formate dehydrogenase accessory protein FdhE	NA	NA	NA	NA
AYE21917.1\|508048_508681_-	formate dehydrogenase cytochrome b556 subunit	NA	NA	NA	NA
AYE21918.1\|508677_509580_-	formate dehydrogenase subunit beta	NA	NA	NA	NA
AYE21919.1\|509592_512643_-	formate dehydrogenase-N subunit alpha	A0A077SK27	Escherichia_phage	2.7e-06	24.1
AYE21920.1\|512837_513674_+	sulfurtransferase FdhD	NA	NA	NA	NA
AYE21921.1\|515144_516245_+	DUF3829 domain-containing protein	NA	NA	NA	NA
AYE21922.1\|516600_516924_-	AzlD domain-containing protein	NA	NA	NA	NA
AYE21923.1\|516923_517583_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
AYE25667.1\|517665_518232_+	XRE family transcriptional regulator	NA	NA	NA	NA
AYE21924.1\|518320_518635_-	L-rhamnose mutarotase	NA	NA	NA	NA
AYE21925.1\|518631_519780_-	lactaldehyde reductase	NA	NA	NA	NA
AYE21926.1\|519906_520734_-	rhamnulose-1-phosphate aldolase	NA	NA	NA	NA
AYE21927.1\|520876_522136_-	L-rhamnose isomerase	NA	NA	NA	NA
AYE21928.1\|522132_523602_-	rhamnulokinase	NA	NA	NA	NA
AYE21929.1\|523889_524726_+	HTH-type transcriptional activator RhaS	NA	NA	NA	NA
AYE21930.1\|524878_525727_+	HTH-type transcriptional activator RhaR	NA	NA	NA	NA
AYE21931.1\|525723_526758_-	rhamnose/proton symporter RhaT	NA	NA	NA	NA
AYE21932.1\|527376_528060_+	hypothetical protein	NA	NA	NA	NA
AYE21933.1\|528217_529525_-	TRAP transporter large permease	NA	NA	NA	NA
AYE21934.1\|529517_530033_-	TRAP transporter small permease	NA	NA	NA	NA
AYE21935.1\|530051_531035_-	hypothetical protein	NA	NA	NA	NA
AYE21936.1\|531363_531984_+	superoxide dismutase [Mn]	Q56AR7	Bacillus_thuringiensis_phage	7.1e-63	58.4
AYE21937.1\|531990_532743_+	MOSC domain-containing protein	NA	NA	NA	NA
AYE21938.1\|532754_533150_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
AYE21939.1\|533270_533474_+	hypothetical protein	NA	NA	NA	NA
AYE21940.1\|533521_534895_-	two-component system sensor histidine kinase CpxA	W8CYF6	Bacillus_phage	7.2e-15	25.6
AYE21941.1\|534891_535590_-	DNA-binding response regulator	Q6XM27	Feldmannia_irregularis_virus	5.3e-06	30.3
AYE21942.1\|535740_536241_+	stress adaptor protein CpxP	NA	NA	NA	NA
536264:536306	attL	NA	NA	NA	NA
AYE21943.1\|536426_537407_-\|integrase	integrase	S4TP66	Salmonella_phage	8.0e-186	99.7
AYE21944.1\|537476_537770_-	transcriptional regulator	Q1JS37	Enterobacteria_phage	1.0e-48	99.0
AYE21945.1\|537906_538179_+	hypothetical protein	Q1JS36	Enterobacteria_phage	1.4e-47	100.0
AYE21946.1\|538348_538849_+	replication protein B	M1SV55	Escherichia_phage	2.6e-92	100.0
AYE21947.1\|538912_539137_+	DUF2732 domain-containing protein	S4TP68	Salmonella_phage	4.7e-33	100.0
AYE21948.1\|539438_539663_+	hypothetical protein	S4TRY6	Salmonella_phage	6.5e-35	98.6
AYE21949.1\|539659_539935_+	hypothetical protein	U5N3W1	Enterobacteria_phage	1.9e-44	97.8
AYE21950.1\|539924_542201_+	replication protein A	A0A0F7LBQ2	Escherichia_phage	0.0e+00	97.9
AYE21951.1\|543283_544318_-\|portal	phage portal protein	M1SV64	Escherichia_phage	4.2e-201	99.7
AYE21952.1\|544317_546090_-	oxidoreductase	A0A0F7LCK3	Escherichia_phage	0.0e+00	99.8
AYE21953.1\|546263_547118_+\|capsid	capsid scaffolding protein	Q778Z1	Enterobacteria_phage	8.6e-136	99.3
AYE21954.1\|547172_548246_+\|capsid	phage major capsid protein, P2 family	Q778Y7	Enterobacteria_phage	1.1e-201	99.7
AYE21955.1\|548249_548993_+\|terminase	terminase	A0A0F7LBP7	Escherichia_phage	1.7e-124	98.8
AYE21956.1\|549091_549601_+\|head	head completion/stabilization protein	U5N0S3	Enterobacteria_phage	1.1e-90	100.0
AYE21957.1\|549600_549804_+\|tail	phage tail protein	A0A0F7LCN2	Escherichia_phage	3.0e-31	100.0
AYE21958.1\|549807_550089_+\|holin	holin	A0A0F7LA12	Escherichia_phage	1.3e-43	100.0
AYE21959.1\|550088_550586_+	lysozyme	A0A0F7LBS0	Escherichia_phage	3.1e-93	100.0
AYE21960.1\|550600_551026_+	protein lysA	A0A0F7LDU9	Escherichia_phage	3.5e-61	98.6
AYE21961.1\|551013_551439_+	protein lysB	Q7Y4E2	Escherichia_virus	6.1e-66	95.7
AYE21962.1\|551410_551584_+\|lysis	phage lysis protein	Q7Y4E1	Escherichia_virus	2.3e-24	96.5
AYE21963.1\|551546_552014_+\|tail	phage tail protein	Q7Y4E0	Escherichia_virus	1.9e-81	99.4
AYE21964.1\|552006_552459_+	phage virion morphogenesis protein	A0A0F7LBV9	Escherichia_phage	4.1e-76	99.3
AYE21965.1\|552525_553161_+\|plate	phage baseplate assembly protein V	A0A0F7LBP2	Escherichia_phage	1.6e-110	97.6
AYE21966.1\|553157_553505_+\|plate	baseplate assembly protein	A0A0F7L9X3	Escherichia_phage	1.7e-58	100.0
AYE21967.1\|553509_554418_+\|plate	baseplate assembly protein	A0A0F7LCJ3	Escherichia_phage	1.2e-162	100.0
AYE21968.1\|554410_555022_+\|tail	phage tail protein I	A0A0F7LA36	Escherichia_phage	2.4e-116	99.5
AYE21969.1\|555018_556203_+\|tail	phage tail protein	A0A0F7LBW5	Escherichia_phage	1.0e-163	78.5
AYE21970.1\|557741_558335_+	DNA-invertase	A0A0F7LA37	Escherichia_phage	1.2e-104	98.0
AYE21971.1\|558394_559585_+\|tail	phage tail protein	A0A0F7LBW9	Escherichia_phage	1.6e-225	100.0
AYE21972.1\|559597_560116_+\|tail	phage major tail tube protein	A0A0F7LDZ1	Escherichia_phage	1.4e-93	100.0
AYE21973.1\|560173_560449_+\|tail	phage tail assembly protein	A0A0F7LDQ8	Escherichia_phage	5.7e-41	100.0
AYE25668.1\|560481_560601_+\|tail	GpE family phage tail protein	A0A0F7LCR6	Escherichia_phage	1.0e-15	100.0
AYE21974.1\|560593_563041_+\|tail	phage tail tape measure protein	Q858U7	Yersinia_virus	0.0e+00	98.4
AYE21975.1\|563055_563535_+\|tail	phage tail protein	A0A0F7LBX3	Escherichia_phage	4.3e-84	98.1
AYE21976.1\|563534_564698_+	hypothetical protein	U5N3V4	Enterobacteria_phage	4.1e-205	99.0
AYE21977.1\|564743_564998_+	transcriptional regulator	A0A0F7LDQ9	Escherichia_phage	6.1e-45	100.0
565863:565905	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1840503 : 1849674

Enterobacteria_phage(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYE23028.1\|1840503_1841451_+	ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	1.6e-10	27.8
AYE23029.1\|1841434_1842166_+	ABC transporter permease	NA	NA	NA	NA
AYE23030.1\|1842146_1842254_-	hypothetical protein	NA	NA	NA	NA
AYE23031.1\|1842313_1843045_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	1.3e-100	87.9
AYE23032.1\|1843267_1844953_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	6.2e-279	91.1
AYE23033.1\|1844949_1845669_+	two-component system response regulator YehT	NA	NA	NA	NA
AYE23034.1\|1845715_1846183_+	DUF1456 domain-containing protein	Q9EYF4	Enterobacteria_phage	4.3e-73	89.7
AYE23035.1\|1846239_1846770_-	lipoprotein	NA	NA	NA	NA
AYE23036.1\|1846941_1847400_-	hypothetical protein	Q9EYF5	Enterobacteria_phage	6.4e-53	72.5
AYE23037.1\|1847640_1849674_-\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	1.0e-54	26.9

DBSCAN-SWA_3

1916871 : 1927378

Enterobacteria_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYE23086.1\|1916871_1918275_+	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	4.0e-21	26.5
AYE23087.1\|1918452_1919346_+	UTP--glucose-1-phosphate uridylyltransferase	A0A127AW70	Bacillus_phage	4.8e-44	42.2
AYE23088.1\|1919722_1920808_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.6e-102	53.9
AYE23089.1\|1920807_1921707_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	5.1e-30	36.0
AYE23090.1\|1921754_1922633_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.1e-108	65.5
AYE23091.1\|1922633_1923185_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.3e-52	58.0
AYE23092.1\|1923190_1924165_+	CDP-6-deoxy-delta-3,4-glucoseen reductase	NA	NA	NA	NA
AYE23093.1\|1924180_1924954_+	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
AYE23094.1\|1924958_1926038_+	CDP-glucose 4,6-dehydratase	A0A222YY99	Synechococcus_phage	1.7e-16	24.5
AYE23095.1\|1926064_1927378_+	LPS biosynthesis protein	H8ZJ36	Ostreococcus_tauri_virus	7.0e-52	35.1

DBSCAN-SWA_4

2570212 : 2577146

Escherichia_phage(33.33%)

integrase,tRNA

attL 2566101:2566113|attR 2572559:2572571

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2566101:2566113	attL	NA	NA	NA	NA
AYE23684.1\|2570212_2570647_+	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	1.2e-29	52.1
AYE23685.1\|2570696_2571035_-	QacE family quaternary ammonium compound efflux SMR transporter	NA	NA	NA	NA
AYE23686.1\|2571027_2571180_-	multidrug transporter	NA	NA	NA	NA
AYE23687.1\|2571147_2571339_+\|integrase	integrase	A0A0U2JGI6	Escherichia_phage	1.6e-29	96.8
AYE23688.1\|2571390_2572326_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	7.2e-144	97.3
AYE23689.1\|2572369_2573743_-	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	3.6e-51	32.0
2572559:2572571	attR	NA	NA	NA	NA
AYE23690.1\|2574244_2575399_-	chemoreceptor protein	A0A2H4J162	uncultured_Caudovirales_phage	1.5e-10	27.7
AYE23691.1\|2575649_2575829_-	hypothetical protein	NA	NA	NA	NA
AYE23692.1\|2575809_2576373_-	DNA endonuclease SmrA	NA	NA	NA	NA
AYE23693.1\|2576630_2577146_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	6.6e-22	53.5

DBSCAN-SWA_5

2730218 : 2829696

106

Enterobacteria_phage(28.0%)

portal,protease,integrase,holin,lysis,tRNA,tail

attL 2782291:2782320|attR 2829832:2829861

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYE23833.1\|2730218_2730914_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
AYE23834.1\|2730971_2732882_-	ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	1.1e-90	32.4
AYE23835.1\|2733012_2733357_+	RidA family protein	NA	NA	NA	NA
AYE23836.1\|2733362_2733542_-	YoaH family protein	NA	NA	NA	NA
AYE23837.1\|2733622_2734987_+	aminodeoxychorismate synthase component 1	A0A0B5J984	Pandoravirus	3.6e-43	34.5
AYE23838.1\|2734990_2735569_+	coenzyme A pyrophosphatase	NA	NA	NA	NA
AYE23839.1\|2735832_2737197_+	L-serine ammonia-lyase	NA	NA	NA	NA
AYE23840.1\|2737334_2738936_+	cyclic diguanylate phosphodiesterase	NA	NA	NA	NA
AYE23841.1\|2738957_2740517_-	TerC family protein	A0A0R6PEZ3	Moraxella_phage	9.5e-40	44.4
AYE23842.1\|2740504_2740840_-	hypothetical protein	NA	NA	NA	NA
AYE23843.1\|2740989_2741958_+	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
AYE23844.1\|2742010_2742811_+	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
AYE23845.1\|2742823_2743675_+	PTS mannose transporter subunit IID	NA	NA	NA	NA
AYE25748.1\|2744547_2745168_+	hypothetical protein	NA	NA	NA	NA
AYE23846.1\|2745164_2745974_-	23S rRNA (guanine(745)-N(1))-methyltransferase	NA	NA	NA	NA
AYE23847.1\|2746039_2747785_-	peptidoglycan glycosyltransferase FtsI	NA	NA	NA	NA
AYE23848.1\|2748004_2748214_-	cold-shock protein CspC	A0A1W6JNX5	Morganella_phage	1.6e-22	78.1
AYE23849.1\|2748226_2748370_-	DUF2627 domain-containing protein	NA	NA	NA	NA
AYE23850.1\|2749018_2749306_-	hypothetical protein	NA	NA	NA	NA
AYE23851.1\|2749376_2749520_-	PhoP regulon feedback inhibition membrane protein MgrB	NA	NA	NA	NA
AYE23852.1\|2749677_2749917_+	hypothetical protein	NA	NA	NA	NA
AYE23853.1\|2750128_2750920_-	DNA-binding transcriptional regulator KdgR	NA	NA	NA	NA
AYE23854.1\|2751095_2752469_+	MFS transporter	NA	NA	NA	NA
AYE23855.1\|2752516_2753398_-\|protease	protease HtpX	NA	NA	NA	NA
AYE23856.1\|2753590_2755639_-\|tail,protease	tail-specific protease	A0A0R6PIZ1	Moraxella_phage	8.0e-87	33.5
AYE23857.1\|2755658_2756345_-	RNA chaperone ProQ	NA	NA	NA	NA
AYE23858.1\|2756442_2757027_-	Free methionine-R-sulfoxide reductase	NA	NA	NA	NA
AYE23859.1\|2757068_2758352_+	paraquat-inducible protein A	NA	NA	NA	NA
AYE23860.1\|2758320_2760954_+	MCE family protein	NA	NA	NA	NA
AYE25749.1\|2761031_2762471_+	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	NA	NA	NA	NA
AYE23861.1\|2762585_2762825_+	DUF1480 domain-containing protein	NA	NA	NA	NA
AYE23862.1\|2762935_2763127_+	DUF1482 domain-containing protein	NA	NA	NA	NA
AYE23863.1\|2763145_2763796_-	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	1.1e-58	51.4
AYE23864.1\|2764019_2764184_-	hypothetical protein	NA	NA	NA	NA
AYE23865.1\|2764469_2765192_-	guanine nucleotide exchange factor sopE2	NA	NA	NA	NA
AYE23866.1\|2765875_2766271_+	DUF1398 domain-containing protein	C6ZCX4	Enterobacteria_phage	9.2e-16	32.8
AYE23867.1\|2766600_2767077_+	hypothetical protein	NA	NA	NA	NA
AYE23868.1\|2767448_2767868_-	N-acetyltransferase	NA	NA	NA	NA
AYE23869.1\|2767999_2768194_-	hypothetical protein	NA	NA	NA	NA
AYE23870.1\|2768240_2768510_+	hypothetical protein	B6SCX2	Bacteriophage	3.1e-07	47.9
AYE23871.1\|2768675_2768816_+	hypothetical protein	NA	NA	NA	NA
AYE25750.1\|2771136_2771337_-	hypothetical protein	NA	NA	NA	NA
AYE23872.1\|2771954_2772869_+	protein PagO	NA	NA	NA	NA
AYE23873.1\|2773001_2773160_+	hypothetical protein	NA	NA	NA	NA
AYE23874.1\|2773169_2773784_+	disulfide bond formation protein B	NA	NA	NA	NA
AYE23875.1\|2774536_2774803_-	hypothetical protein	NA	NA	NA	NA
AYE23876.1\|2774931_2775057_-	arsenic transporter	NA	NA	NA	NA
AYE23877.1\|2775625_2775826_+	phage virulence factor	NA	NA	NA	NA
AYE23878.1\|2778527_2779019_-	DUF1441 domain-containing protein	Q9EYD0	Enterobacteria_phage	3.5e-41	55.6
AYE23879.1\|2779073_2779262_+	hypothetical protein	NA	NA	NA	NA
AYE23880.1\|2779326_2779494_+	lytic enzyme	NA	NA	NA	NA
AYE23881.1\|2780336_2780624_-	lytic enzyme	Q8HA86	Salmonella_phage	9.9e-28	93.7
AYE23882.1\|2780756_2781251_+	RecE	A0A0U2I1R6	Escherichia_phage	4.8e-22	70.3
2782291:2782320	attL	NA	NA	NA	NA
AYE23883.1\|2783108_2783909_+	hypothetical protein	NA	NA	NA	NA
AYE23884.1\|2784388_2785111_+	guanine nucleotide exchange factor SopE	NA	NA	NA	NA
AYE23885.1\|2785312_2785882_-\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	1.5e-96	91.0
AYE23886.1\|2788132_2788375_-	hypothetical protein	NA	NA	NA	NA
AYE23887.1\|2788413_2789277_-\|tail	phage tail protein	K7PKJ2	Enterobacteria_phage	9.0e-48	78.9
AYE23888.1\|2791836_2792541_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	2.4e-67	63.1
AYE23889.1\|2792444_2793176_-\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	1.0e-113	75.6
AYE23890.1\|2793185_2793881_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	1.0e-89	66.7
AYE23891.1\|2793970_2794504_+	superoxide dismutase [Cu-Zn] SodC1	Q9MC02	Salmonella_phage	1.8e-46	54.0
AYE23892.1\|2794620_2795118_-	Ail/OmpX	A0A1B0VBR9	Salmonella_phage	1.4e-16	36.6
AYE23893.1\|2795216_2795549_-\|tail	phage tail protein	A5LH39	Enterobacteria_phage	2.6e-35	61.5
AYE25751.1\|2795545_2798533_-\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	1.7e-266	62.1
AYE23894.1\|2798612_2798942_-\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	5.0e-23	50.9
AYE23895.1\|2798938_2799337_-\|tail	phage minor tail protein G	K7PLV8	Enterobacteria_phage	7.3e-29	56.1
AYE23896.1\|2799382_2800132_-\|tail	phage tail protein	A0A291AWU6	Escherichia_phage	3.1e-89	68.2
AYE23897.1\|2800143_2800545_-\|tail	phage tail protein	K7PHM6	Enterobacterial_phage	5.8e-42	60.2
AYE23898.1\|2800541_2801108_-\|tail	phage tail protein	Q9G063	Phage_Gifsy-2	2.1e-13	95.7
AYE23899.1\|2801088_2801388_-	ATP-binding protein	K7PH43	Enterobacteria_phage	4.5e-15	45.1
AYE23900.1\|2801380_2801704_-	recombinase RecA	K7PLV6	Enterobacteria_phage	7.7e-29	61.3
AYE25753.1\|2801794_2803876_-	peptidase S14	A0A291AWT6	Escherichia_phage	4.8e-265	69.5
AYE25752.1\|2803799_2805317_-\|portal	phage portal protein	A0A291AWU2	Escherichia_phage	7.1e-173	64.5
AYE23901.1\|2805343_2805550_-	primosomal replication protein PriB/PriC domain protein	A0A1W6JT66	Pseudomonas_phage	2.9e-05	53.3
AYE23902.1\|2805546_2807685_-	DNA packaging protein	A5LH27	Enterobacteria_phage	3.4e-290	72.6
AYE23903.1\|2807641_2808175_-	DNA breaking-rejoining protein	A0A291AWV8	Escherichia_phage	1.0e-33	48.1
AYE25755.1\|2808382_2808862_-\|lysis	lysis protein	Q56118	Enterobacteria_phage	1.4e-55	77.0
AYE23904.1\|2808879_2809332_-	lysozyme	A0A0M4R365	Salmonella_phage	2.3e-79	97.3
AYE25754.1\|2809315_2809645_-\|holin	phage holin, lambda family	A0A0M3ULK9	Salmonella_phage	5.8e-56	100.0
AYE23905.1\|2809920_2810607_+	PipA/GogA/GtgA family type III secretion system effector	Q9MBM0	Phage_Gifsy-2	1.8e-131	99.6
AYE23906.1\|2810967_2811417_+	hypothetical protein	NA	NA	NA	NA
AYE25756.1\|2811790_2812315_-	hypothetical protein	NA	NA	NA	NA
AYE23907.1\|2812411_2813101_-	antiterminator	I6PDF8	Cronobacter_phage	2.1e-60	54.9
AYE23908.1\|2813230_2813458_-	DNA breaking-rejoining protein	A0A0M4RU10	Salmonella_phage	2.2e-14	66.7
AYE23909.1\|2813454_2814054_-	DUF1367 domain-containing protein	A0A0U2RT94	Escherichia_phage	4.7e-96	82.9
AYE23910.1\|2814117_2814423_-	hypothetical protein	NA	NA	NA	NA
AYE23911.1\|2814845_2815037_+	hypothetical protein	NA	NA	NA	NA
AYE23912.1\|2815054_2817034_-	hypothetical protein	A0A2P0VMX1	Tetraselmis_virus	1.9e-162	46.3
AYE23913.1\|2817430_2818561_+	GGDEF domain-containing protein	NA	NA	NA	NA
AYE23914.1\|2818847_2819243_-	DUF977 domain-containing protein	A0A088CBK9	Shigella_phage	9.8e-18	38.8
AYE23915.1\|2819255_2819717_-	replication protein	A0A0U2JGJ0	Escherichia_phage	3.5e-67	75.5
AYE23916.1\|2819709_2820708_-	DUF1376 domain-containing protein	A0A0U2RT81	Escherichia_phage	4.1e-121	67.3
AYE23917.1\|2820754_2821249_-	hypothetical protein	NA	NA	NA	NA
AYE23918.1\|2821235_2821490_-	XRE family transcriptional regulator	K7PKH4	Enterobacteria_phage	5.3e-17	60.9
AYE23919.1\|2821588_2821987_+	transcriptional regulator	K7PH19	Enterobacteria_phage	1.2e-18	56.0
AYE23920.1\|2822389_2822656_+	hypothetical protein	NA	NA	NA	NA
AYE23921.1\|2822993_2823269_+	hypothetical protein	NA	NA	NA	NA
AYE23922.1\|2823272_2823479_+	cell division inhibitor protein	I6PBM9	Cronobacter_phage	3.0e-10	45.6
AYE23923.1\|2823554_2823890_+	hypothetical protein	NA	NA	NA	NA
AYE23924.1\|2824030_2826721_+	exonuclease VIII	Q9QF34	Lambdoid_phage	4.0e-118	72.8
AYE23925.1\|2826713_2827544_+	recombination and repair protein RecT	A0A1P8DTF2	Proteus_phage	1.1e-103	71.6
AYE23926.1\|2827590_2827776_+	hypothetical protein	NA	NA	NA	NA
AYE25757.1\|2828066_2828303_+	hypothetical protein	NA	NA	NA	NA
AYE23927.1\|2828363_2828642_+	excisionase	A0A2H4J5E1	uncultured_Caudovirales_phage	1.4e-10	37.5
AYE23928.1\|2828616_2829696_+\|integrase	integrase	A0A2H4IYC8	uncultured_Caudovirales_phage	3.0e-101	52.5
2829832:2829861	attR	NA	NA	NA	NA

DBSCAN-SWA_6

3723181 : 3767558

Enterobacteria_phage(77.61%)

portal,protease,integrase,coat,lysis,terminase,tail

attL 3723615:3723660|attR 3765005:3765050

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYE24721.1\|3723181_3723451_-	DUF4102 domain-containing protein	Q7M297	Enterobacteria_phage	1.4e-20	63.8
3723615:3723660	attL	NA	NA	NA	NA
AYE24722.1\|3723948_3724311_+	GtrA family protein	A0A192Y6N5	Salmonella_phage	5.0e-61	100.0
AYE24723.1\|3724307_3725240_+	glycosyltransferase	A8CG95	Salmonella_phage	5.5e-176	100.0
AYE24724.1\|3725229_3726687_+	hypothetical protein	A8CG94	Salmonella_phage	1.3e-240	100.0
AYE24725.1\|3726745_3728749_-	endorhamnosidase	Q76H47	Enterobacteria_phage	0.0e+00	99.9
AYE24726.1\|3728884_3729133_+	toxin-antitoxin system HicB family antitoxin	Q76H48	Enterobacteria_phage	1.8e-38	100.0
AYE24727.1\|3729153_3729453_-	hypothetical protein	Q76H12	Enterobacteria_phage	5.1e-51	100.0
AYE24728.1\|3729585_3731562_-	DNA transfer protein	Q76H13	Enterobacteria_phage	0.0e+00	100.0
AYE24729.1\|3731561_3732998_-	DNA transfer protein	Q76H14	Enterobacteria_phage	7.7e-246	100.0
AYE24730.1\|3733008_3733698_-	DNA transfer protein	A0A2H5BFK5	Salmonella_phage	2.9e-118	100.0
AYE24731.1\|3733700_3734156_-	hypothetical protein	Q76H16	Enterobacteria_phage	1.8e-87	100.0
AYE24732.1\|3734155_3734857_-\|tail	phage tail protein	Q76H17	Enterobacteria_phage	1.7e-76	100.0
AYE24733.1\|3734860_3736279_-	hypothetical protein	Q76H18	Enterobacteria_phage	6.4e-277	100.0
AYE24734.1\|3736238_3736739_-	hypothetical protein	Q76H19	Enterobacteria_phage	4.2e-90	100.0
AYE24735.1\|3736722_3737283_-	hypothetical protein	C6ZR11	Salmonella_phage	9.8e-104	100.0
AYE24736.1\|3737323_3738616_-\|coat	coat protein	Q76H21	Enterobacteria_phage	1.1e-243	100.0
AYE24737.1\|3738615_3739527_-	scaffolding protein	Q76H22	Enterobacteria_phage	1.5e-162	100.0
AYE24738.1\|3739540_3741718_-\|portal	portal protein	Q76H23	Enterobacteria_phage	0.0e+00	99.9
AYE24739.1\|3741717_3743217_-\|terminase	terminase	Q76H24	Enterobacteria_phage	2.8e-307	100.0
AYE24740.1\|3743194_3743683_-	DNA-packaging protein	Q76H25	Enterobacteria_phage	1.0e-88	100.0
AYE24741.1\|3743686_3744091_-	Decoration protein	Q76H26	Enterobacteria_phage	1.1e-67	100.0
AYE24742.1\|3744090_3744480_-	hypothetical protein	Q76H27	Enterobacteria_phage	3.9e-75	100.0
AYE24743.1\|3744483_3744726_-	hypothetical protein	Q76H60	Enterobacteria_phage	1.7e-33	100.0
AYE24744.1\|3744948_3745479_-	hypothetical protein	Q76H61	Enterobacteria_phage	1.3e-94	100.0
AYE24745.1\|3745432_3745657_-	hypothetical protein	A0A1V0E5I0	Salmonella_phage	3.6e-25	88.7
AYE24746.1\|3745691_3746159_-\|lysis	lysis protein	Q76H63	Enterobacteria_phage	1.7e-77	100.0
AYE25791.1\|3746155_3746653_-	lysozyme	B8K1G9	Salmonella_phage	4.5e-92	100.0
AYE24747.1\|3746630_3746834_-	hypothetical protein	I6R0S9	Salmonella_phage	1.1e-33	100.0
AYE24748.1\|3746918_3747152_-	hypothetical protein	M1E3N9	Enterobacteria_phage	1.1e-21	87.0
AYE24749.1\|3747264_3748038_-	antitermination protein	Q76H66	Enterobacteria_phage	8.1e-133	100.0
AYE24750.1\|3748034_3748214_-	hypothetical protein	Q76H67	Enterobacteria_phage	1.9e-24	100.0
AYE24751.1\|3748194_3748398_-	protein ninH	I6RSQ6	Salmonella_phage	7.2e-33	100.0
AYE24752.1\|3748394_3748619_-	protein ninY	Q76H69	Enterobacteria_phage	6.3e-38	100.0
AYE24753.1\|3748615_3749227_-	recombination protein NinG	Q76H70	Enterobacteria_phage	7.9e-99	100.0
AYE24754.1\|3749219_3749396_-	protein ninF	Q76H71	Enterobacteria_phage	6.7e-27	100.0
AYE24755.1\|3749388_3749730_-	protein ninX	Q76H72	Enterobacteria_phage	2.1e-64	100.0
AYE24756.1\|3749732_3749909_-	NinE family protein	Q76H73	Enterobacteria_phage	1.0e-27	100.0
AYE24757.1\|3749875_3750049_-	protein ninD	Q76H74	Enterobacteria_phage	2.3e-32	100.0
AYE24758.1\|3750045_3750501_-	recombination protein NinB	Q76H49	Enterobacteria_phage	4.7e-80	100.0
AYE24759.1\|3750556_3750826_-	hypothetical protein	Q76H50	Enterobacteria_phage	4.9e-45	100.0
AYE24760.1\|3750822_3752199_-	replicative DNA helicase	Q76H51	Enterobacteria_phage	1.9e-254	100.0
AYE24761.1\|3752195_3753017_-	replication of DNA	Q76H52	Enterobacteria_phage	5.2e-154	100.0
AYE24762.1\|3753199_3753481_-	hypothetical protein	Q76H54	Enterobacteria_phage	4.3e-44	100.0
AYE24763.1\|3753591_3753807_-	transcriptional regulator	Q76H55	Enterobacteria_phage	1.3e-32	100.0
AYE24764.1\|3753917_3754607_+	hypothetical protein	Q76H56	Enterobacteria_phage	1.3e-126	100.0
AYE24765.1\|3754771_3755851_+	hypothetical protein	A0A192Y6S0	Salmonella_phage	1.5e-193	100.0
AYE24766.1\|3755889_3756093_-	hypothetical protein	A0A2H5BFH9	Salmonella_phage	2.0e-27	100.0
AYE24767.1\|3756456_3756759_+	regulator	Q76H58	Enterobacteria_phage	9.7e-50	100.0
AYE24768.1\|3756771_3757359_-	superinfection exclusion protein B	Q76H59	Enterobacteria_phage	1.4e-100	100.0
AYE24769.1\|3757572_3757767_+	restriction endonuclease	Q76H34	Enterobacteria_phage	1.9e-30	100.0
AYE24770.1\|3757850_3758495_+	pentapeptide repeat-containing protein	Q76H35	Enterobacteria_phage	6.5e-51	100.0
AYE24771.1\|3758528_3758816_+	hypothetical protein	Q76H36	Enterobacteria_phage	2.7e-49	100.0
AYE24772.1\|3759091_3759406_+	superinfection exclusion protein	Q76H37	Enterobacteria_phage	1.5e-56	100.0
AYE24773.1\|3759490_3759649_+\|protease	protease FtsH-inhibitory lysogeny factor CIII	Q76H38	Enterobacteria_phage	2.4e-23	100.0
AYE24774.1\|3759629_3759818_+	protein kil	I6S647	Salmonella_phage	3.7e-31	100.0
AYE24775.1\|3759947_3760655_+	recombinase	Q76H40	Enterobacteria_phage	3.1e-139	100.0
AYE24776.1\|3760654_3760939_+	sigma-70 family RNA polymerase sigma factor	Q76H41	Enterobacteria_phage	1.4e-45	100.0
AYE24777.1\|3760985_3761279_+	RecBCD nuclease inhibitor	Q76H42	Enterobacteria_phage	1.4e-48	100.0
AYE24778.1\|3761289_3761460_+	DUF2737 domain-containing protein	Q76H43	Enterobacteria_phage	1.6e-25	100.0
AYE24779.1\|3761456_3761966_+	hypothetical protein	Q76H44	Enterobacteria_phage	2.8e-89	100.0
AYE24780.1\|3761962_3762196_+	hypothetical protein	NA	NA	NA	NA
AYE24781.1\|3762182_3762827_+	hypothetical protein	Q76H45	Enterobacteria_phage	1.4e-122	99.5
AYE24782.1\|3762826_3763111_+	DUF4752 domain-containing protein	Q76H46	Enterobacteria_phage	1.6e-49	100.0
AYE24783.1\|3763103_3763388_+	ASCH domain-containing protein	Q76H28	Enterobacteria_phage	1.4e-50	100.0
AYE24784.1\|3763599_3763950_+	DNA-binding protein	Q76H29	Enterobacteria_phage	3.7e-61	100.0
AYE25792.1\|3764321_3764990_+\|integrase	site-specific integrase	A0A2H5BFK7	Salmonella_phage	8.0e-129	100.0
AYE24785.1\|3765195_3766443_-	gamma-glutamyl-phosphate reductase	A0A1X9I5D4	Streptococcus_phage	5.5e-99	47.9
3765005:3765050	attR	NA	NA	NA	NA
AYE24786.1\|3766454_3767558_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	6.9e-61	39.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP022964

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 2430

Salmonella_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYE25828.1\|242_710_+	hypothetical protein	A0A1B0V7H9	Salmonella_phage	2.7e-38	63.9
AYE25829.1\|817_1069_-	hypothetical protein	NA	NA	NA	NA
AYE25830.1\|1131_1539_+	hypothetical protein	A0A1B0V7H9	Salmonella_phage	1.8e-22	96.4
AYE25831.1\|1566_1929_+	hypothetical protein	A0A1B0V7H9	Salmonella_phage	1.1e-47	82.4
AYE25904.1\|2076_2430_+	hypothetical protein	A0A1B0V7H9	Salmonella_phage	3.7e-40	100.0

DBSCAN-SWA_2

7285 : 35878

uncultured_Caudovirales_phage(40.0%)

coat,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYE25836.1\|7285_7996_-	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	2.1e-95	73.4
AYE25837.1\|8096_8420_-	ArsR family transcriptional regulator	NA	NA	NA	NA
AYE25838.1\|8525_9659_+	permease	NA	NA	NA	NA
AYE25839.1\|10358_13346_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.7e-295	53.5
AYE25840.1\|13388_14033_-	resolvase	A0A1V0E035	Clostridioides_phage	9.8e-07	28.3
AYE25841.1\|14413_15076_+	peptidyl-arginine deiminase	E5FFJ3	Burkholderia_phage	2.6e-07	25.2
AYE25842.1\|15175_15460_+	CopG family transcriptional regulator	NA	NA	NA	NA
AYE25843.1\|15499_16590_-\|transposase	IS4 family transposase	NA	NA	NA	NA
AYE25844.1\|16668_17694_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	6.6e-74	44.1
AYE25905.1\|17737_17845_+	hypothetical protein	NA	NA	NA	NA
AYE25845.1\|17881_18085_-	hypothetical protein	NA	NA	NA	NA
AYE25846.1\|18199_19267_-	arsenical-resistance protein	NA	NA	NA	NA
AYE25847.1\|19263_19770_-	arsenate reductase ArsC	A0A2H4J8A6	uncultured_Caudovirales_phage	3.0e-27	42.6
AYE25848.1\|19766_20534_-	FMN reductase	A0A2H4J5V6	uncultured_Caudovirales_phage	1.4e-76	63.3
AYE25849.1\|20530_20863_-	transcriptional regulator	NA	NA	NA	NA
AYE25850.1\|21010_21748_+	resolvase	NA	NA	NA	NA
AYE25851.1\|21744_21969_+	hypothetical protein	NA	NA	NA	NA
AYE25852.1\|22179_23673_+\|transposase	IS91 family transposase	NA	NA	NA	NA
AYE25853.1\|23703_23955_+	hypothetical protein	NA	NA	NA	NA
AYE25854.1\|23848_24151_-	phosphoglucosamine mutase	NA	NA	NA	NA
AYE25855.1\|24237_25053_-	sulfonamide-resistant dihydropteroate synthase Sul2	A0A0B5J4J5	Pandoravirus	5.9e-09	27.6
AYE25856.1\|25145_26235_+\|transposase	IS4 family transposase	NA	NA	NA	NA
AYE25857.1\|26377_26653_+	hypothetical protein	NA	NA	NA	NA
AYE25858.1\|26676_27273_+	aminopeptidase	NA	NA	NA	NA
AYE25906.1\|27324_27681_-	DNA distortion polypeptide 3	NA	NA	NA	NA
AYE25859.1\|27817_28264_-	hypothetical protein	NA	NA	NA	NA
AYE25860.1\|28267_29110_-	RepB family plasmid replication initiator protein	NA	NA	NA	NA
AYE25861.1\|29130_29970_-	replication initiation protein	NA	NA	NA	NA
AYE25862.1\|31204_31456_+	plasmid stabilization protein	NA	NA	NA	NA
AYE25863.1\|31445_31727_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A2H4JBF4	uncultured_Caudovirales_phage	3.8e-24	62.4
AYE25864.1\|31872_32196_+	hypothetical protein	A0A0K1LL53	Rhodobacter_phage	9.2e-14	46.1
AYE25865.1\|32240_32486_+	hypothetical protein	NA	NA	NA	NA
AYE25866.1\|32475_32718_+	hypothetical protein	NA	NA	NA	NA
AYE25867.1\|32782_33112_+	hypothetical protein	NA	NA	NA	NA
AYE25868.1\|33154_33334_+	hypothetical protein	NA	NA	NA	NA
AYE25869.1\|33355_33553_+	hypothetical protein	NA	NA	NA	NA
AYE25870.1\|33565_33838_+	hypothetical protein	NA	NA	NA	NA
AYE25907.1\|34163_34709_+	DNA distortion polypeptide 1	NA	NA	NA	NA
AYE25871.1\|34705_35878_+\|coat	spore coat protein CotH	NA	NA	NA	NA

DBSCAN-SWA_3

50883 : 51700

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYE25887.1\|50883_51111_+	hypothetical protein	A0A0E3JIZ4	Enterobacteria_phage	3.2e-13	49.0
AYE25888.1\|51190_51700_+	hypothetical protein	A0A0R6PHV6	Moraxella_phage	2.8e-17	38.5

DBSCAN-SWA_4

60502 : 67146

Enterobacteria_phage(40.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYE25898.1\|60502_60673_+	pilus assembly protein	A0A2L1IV26	Escherichia_phage	2.6e-07	83.9
AYE25899.1\|61398_62259_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
AYE25900.1\|62441_62999_-	recombinase	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
AYE25901.1\|64698_66276_-	chemotaxis protein	A0A1B0V854	Salmonella_phage	1.2e-95	99.4
AYE25902.1\|66585_67146_+\|transposase	transposase	A0A1B0V7I5	Salmonella_phage	1.1e-59	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP022965

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP022963

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. CP022964

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection